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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= epV31389
         (718 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q13630 Cluster: GDP-L-fucose synthetase (EC 1.1.1.271) ...   288   8e-77
UniRef50_A5PHP4 Cluster: GDP-4-dehydro-6-deoxy-D-mannose epimera...   263   3e-69
UniRef50_Q00XZ4 Cluster: GDP-4-keto-6-deoxy-D-mannose epimerase-...   233   2e-60
UniRef50_Q8IJQ5 Cluster: GDP-fucose synthase, putative; n=5; Pla...   176   5e-43
UniRef50_Q74FI1 Cluster: GDP-fucose synthetase; n=7; Bacteria|Re...   150   3e-35
UniRef50_Q0BHR7 Cluster: NAD-dependent epimerase/dehydratase; n=...   136   4e-31
UniRef50_Q2RXT6 Cluster: NAD-dependent epimerase/dehydratase; n=...   134   2e-30
UniRef50_Q3B1R9 Cluster: GDP-L-fucose synthetase; n=3; Bacteria|...   133   4e-30
UniRef50_Q2IZX2 Cluster: NAD-dependent epimerase/dehydratase; n=...   132   6e-30
UniRef50_Q0M6J4 Cluster: NAD-dependent epimerase/dehydratase:3-b...   132   1e-29
UniRef50_Q93N55 Cluster: GDP-4-keto-6 deoxymannose epimerase/red...   130   4e-29
UniRef50_Q5V3C6 Cluster: DTDP-glucose dehydratase; n=23; cellula...   130   4e-29
UniRef50_A4YQ54 Cluster: Bifunctional GDP-fucose synthetase: GDP...   129   8e-29
UniRef50_Q124Z8 Cluster: NAD-dependent epimerase/dehydratase; n=...   125   1e-27
UniRef50_A7IWS0 Cluster: Putative uncharacterized protein B395L;...   124   2e-27
UniRef50_O49213 Cluster: GDP-L-fucose synthase 1; n=181; root|Re...   123   5e-27
UniRef50_A6VG32 Cluster: NAD-dependent epimerase/dehydratase; n=...   121   2e-26
UniRef50_Q0EXY2 Cluster: GDP-fucose synthetase; n=4; Proteobacte...   120   5e-26
UniRef50_Q7BR89 Cluster: GDP-6-deoxy-4-keto-D-mannose-3, 5-epime...   119   6e-26
UniRef50_Q4AI76 Cluster: GDP-L-fucose synthase; n=6; Bacteria|Re...   118   1e-25
UniRef50_Q1VHC4 Cluster: GDP-fucose synthetase chain A; n=1; Psy...   117   3e-25
UniRef50_A5ZJL9 Cluster: Putative uncharacterized protein; n=1; ...   111   4e-25
UniRef50_Q8VU14 Cluster: GDP-4-keto-6-deoxy-D-mannose-3, 5-epime...   110   5e-25
UniRef50_A5GHX4 Cluster: GDP-L fucose synthetase; n=25; Bacteria...   115   1e-24
UniRef50_O84974 Cluster: O-antigen biosynthesis protein; n=5; He...   114   2e-24
UniRef50_A1B1K8 Cluster: NAD-dependent epimerase/dehydratase; n=...   112   9e-24
UniRef50_Q9AQ09 Cluster: Putative nodulation NAD-dependent nucle...   110   3e-23
UniRef50_A2BXU6 Cluster: Putative fucose synthetase; n=1; Prochl...   108   1e-22
UniRef50_Q8VQ41 Cluster: WbdJ; n=13; Bacteria|Rep: WbdJ - Escher...   108   2e-22
UniRef50_Q8L2G9 Cluster: Fcl; n=2; Enterobacteriaceae|Rep: Fcl -...   108   2e-22
UniRef50_Q9XDD7 Cluster: Bme10; n=1; Brucella melitensis|Rep: Bm...   105   8e-22
UniRef50_Q7MV22 Cluster: GDP-fucose synthetase; n=5; Bacteria|Re...   104   2e-21
UniRef50_Q2BI22 Cluster: DTDP-glucose dehydratase; n=1; Neptunii...   103   3e-21
UniRef50_P33217 Cluster: Nodulation protein nolK; n=2; Alphaprot...   103   6e-21
UniRef50_Q67WR5 Cluster: Putative GDP-L-fucose synthase 2; n=4; ...   101   1e-20
UniRef50_A0R4U4 Cluster: NAD dependent epimerase/dehydratase fam...    79   1e-13
UniRef50_Q18EM2 Cluster: Nucleoside-diphosphate-sugar epimerase;...    70   7e-11
UniRef50_Q30CR4 Cluster: LipDig4; n=3; Streptomyces|Rep: LipDig4...    68   3e-10
UniRef50_Q1J353 Cluster: GDP-L-fucose synthase; n=1; Deinococcus...    64   3e-09
UniRef50_A5GEL7 Cluster: NAD-dependent epimerase/dehydratase pre...    64   4e-09
UniRef50_A6GLY7 Cluster: Putative uncharacterized protein; n=1; ...    63   6e-09
UniRef50_Q55412 Cluster: Slr0583 protein; n=3; Chroococcales|Rep...    62   2e-08
UniRef50_Q0W7F9 Cluster: Putative UDP-glucose 4-epimerase; n=1; ...    61   2e-08
UniRef50_Q83DA9 Cluster: NAD dependent epimerase/dehydratase fam...    60   4e-08
UniRef50_Q9K7I2 Cluster: UDP-glucose 4-epimerase; n=17; cellular...    60   5e-08
UniRef50_A1SL10 Cluster: NAD-dependent epimerase/dehydratase; n=...    59   1e-07
UniRef50_Q9ZHQ3 Cluster: 4-ketoreductase; n=2; Actinomycetales|R...    58   2e-07
UniRef50_Q9YCT1 Cluster: DTDP-glucose 4,6-dehydratase; n=2; Ther...    58   2e-07
UniRef50_Q2NIA3 Cluster: Putative UDP-glucose 4-epimerase; n=1; ...    58   2e-07
UniRef50_Q2S4X2 Cluster: Sugar epimerase BlmG; n=2; Bacteroidete...    57   4e-07
UniRef50_Q832Q5 Cluster: NAD-dependent epimerase/dehydratase fam...    56   7e-07
UniRef50_Q5SKQ2 Cluster: UDP-glucose 4-epimerase; n=4; Thermus|R...    56   7e-07
UniRef50_A6CLM3 Cluster: UDP-glucose 4-epimerase; n=1; Bacillus ...    56   7e-07
UniRef50_Q1GN57 Cluster: NAD-dependent epimerase/dehydratase; n=...    55   2e-06
UniRef50_A5GIA6 Cluster: NAD dependent epimerase/dehydratase; n=...    55   2e-06
UniRef50_A0L5P6 Cluster: UDP-glucose 4-epimerase; n=4; Bacteria|...    55   2e-06
UniRef50_Q18EM3 Cluster: Nucleoside-diphosphate-sugar epimerase;...    55   2e-06
UniRef50_Q8TXF0 Cluster: Nucleoside-diphosphate-sugar epimerase;...    54   5e-06
UniRef50_A7HI28 Cluster: NAD-dependent epimerase/dehydratase; n=...    53   6e-06
UniRef50_A2SRX5 Cluster: NAD-dependent epimerase/dehydratase; n=...    53   6e-06
UniRef50_Q8R8R8 Cluster: UDP-glucose 4-epimerase; n=15; Bacteria...    52   1e-05
UniRef50_Q83W21 Cluster: Ata17 protein; n=9; Bacteria|Rep: Ata17...    52   1e-05
UniRef50_A5UK04 Cluster: UDP-glucose 4-epimerase; n=2; Euryarcha...    52   1e-05
UniRef50_Q9RWF7 Cluster: UDP-glucose 4-epimerase, putative; n=63...    51   2e-05
UniRef50_Q9WYX9 Cluster: UDP-glucose 4-epimerase, putative; n=5;...    51   3e-05
UniRef50_A5WE41 Cluster: NAD-dependent epimerase/dehydratase; n=...    51   3e-05
UniRef50_Q70PA0 Cluster: Putative uncharacterized protein; n=1; ...    50   4e-05
UniRef50_A7GZ40 Cluster: dTDP-glucose 4,6-dehydratase; n=1; Camp...    50   4e-05
UniRef50_A6PV21 Cluster: UDP-glucose 4-epimerase; n=1; Victivall...    50   4e-05
UniRef50_Q12UG3 Cluster: NAD-dependent epimerase/dehydratase; n=...    50   4e-05
UniRef50_A3ERU6 Cluster: Nucleoside-diphosphate-sugar epimerase;...    50   6e-05
UniRef50_A0B5G2 Cluster: NAD-dependent epimerase/dehydratase; n=...    50   6e-05
UniRef50_Q8DJM2 Cluster: Nucleotide sugar epimerase; n=61; cellu...    50   8e-05
UniRef50_P72903 Cluster: UDP-glucose-4-epimerase; n=20; Bacteria...    50   8e-05
UniRef50_Q9KDV3 Cluster: UDP-glucose 4-epimerase; n=124; cellula...    50   8e-05
UniRef50_Q5KWG9 Cluster: Nucleotide sugar epimerase; n=1; Geobac...    49   1e-04
UniRef50_Q5KUQ5 Cluster: UDP-glucose 4-epimerase; n=5; Bacteria|...    49   1e-04
UniRef50_Q9FB21 Cluster: Sugar epimerase BlmG; n=1; Streptomyces...    49   1e-04
UniRef50_Q9ABX8 Cluster: UDP-glucose 4-epimerase; n=1; Caulobact...    49   1e-04
UniRef50_Q1VUQ5 Cluster: Sugar epimerase BlmG; n=2; Bacteria|Rep...    49   1e-04
UniRef50_Q0AZA7 Cluster: Nucleoside-diphosphate-sugar epimerase ...    49   1e-04
UniRef50_Q5V6W4 Cluster: UDP-glucose 4-epimerase; n=1; Haloarcul...    48   2e-04
UniRef50_A7DQX9 Cluster: NAD-dependent epimerase/dehydratase; n=...    48   2e-04
UniRef50_Q2FKD1 Cluster: NAD-dependent epimerase/dehydratase fam...    48   2e-04
UniRef50_Q1IM02 Cluster: NAD-dependent epimerase/dehydratase; n=...    48   2e-04
UniRef50_A3PE63 Cluster: UDP-glucose 4-epimerase; n=1; Prochloro...    48   2e-04
UniRef50_O28263 Cluster: UDP-glucose 4-epimerase; n=1; Archaeogl...    48   2e-04
UniRef50_Q661H6 Cluster: Nucleotide sugar epimerase; n=3; Borrel...    48   3e-04
UniRef50_O06485 Cluster: YfnG; n=3; Bacteria|Rep: YfnG - Bacillu...    48   3e-04
UniRef50_Q3ESA4 Cluster: DTDP-glucose 4,6-dehydratase; n=3; Firm...    48   3e-04
UniRef50_Q0C2X5 Cluster: UDP-glucose 4-epimerase; n=1; Hyphomona...    48   3e-04
UniRef50_A3I4Y7 Cluster: Nucleoside-diphosphate-sugar epimerase ...    48   3e-04
UniRef50_Q8THP9 Cluster: DTDP-glucose 4,6-dehydratase; n=3; Meth...    48   3e-04
UniRef50_A0LGE9 Cluster: NAD-dependent epimerase/dehydratase; n=...    47   4e-04
UniRef50_A3ERM8 Cluster: UDP-glucose 4-epimerase; n=1; Leptospir...    47   5e-04
UniRef50_Q2FN70 Cluster: NAD-dependent epimerase/dehydratase pre...    47   5e-04
UniRef50_A7CY79 Cluster: NAD-dependent epimerase/dehydratase; n=...    46   7e-04
UniRef50_Q57664 Cluster: Putative UDP-glucose 4-epimerase; n=3; ...    46   7e-04
UniRef50_Q8KNN2 Cluster: DTDP-D-glucose-4,6-dehydratase; n=4; Ba...    46   0.001
UniRef50_A3HAA1 Cluster: NAD-dependent epimerase/dehydratase; n=...    46   0.001
UniRef50_Q9K6S7 Cluster: UDP-glucose 4-epimerase; n=1; Bacillus ...    45   0.002
UniRef50_Q65E95 Cluster: Putative uncharacterized protein; n=1; ...    45   0.002
UniRef50_A1HMB7 Cluster: NAD-dependent epimerase/dehydratase; n=...    45   0.002
UniRef50_Q5UXR0 Cluster: UDP-glucose 4-epimerase; n=3; Halobacte...    45   0.002
UniRef50_Q2FS05 Cluster: NAD-dependent epimerase/dehydratase; n=...    45   0.002
UniRef50_Q12VP0 Cluster: NAD-dependent epimerase/dehydratase; n=...    45   0.002
UniRef50_Q982P5 Cluster: UDP-glucose 4-epimerase; n=1; Mesorhizo...    45   0.002
UniRef50_Q2SII8 Cluster: Nucleoside-diphosphate-sugar epimerase;...    44   0.003
UniRef50_Q1VGF9 Cluster: Putative uncharacterized protein; n=1; ...    44   0.003
UniRef50_A4CBV8 Cluster: NAD dependent epimerase/dehydratase fam...    44   0.003
UniRef50_Q93N66 Cluster: Dehydratase-like protein; n=14; cellula...    44   0.004
UniRef50_Q6MF46 Cluster: Probable UDP-glucuronat epimerase; n=2;...    44   0.004
UniRef50_Q0LJ11 Cluster: NAD-dependent epimerase/dehydratase; n=...    44   0.004
UniRef50_A0K2B4 Cluster: NAD-dependent epimerase/dehydratase; n=...    44   0.004
UniRef50_Q01T66 Cluster: DTDP-glucose 4,6-dehydratase precursor;...    43   0.007
UniRef50_A6GG02 Cluster: Putative uncharacterized protein; n=1; ...    43   0.007
UniRef50_Q5FQW6 Cluster: UDP-glucose 4-epimerase; n=3; Bacteria|...    43   0.009
UniRef50_O54385 Cluster: UDP-glucose epimerase; n=11; cellular o...    43   0.009
UniRef50_Q4BX31 Cluster: Similar to Nucleoside-diphosphate-sugar...    43   0.009
UniRef50_A6PTX1 Cluster: NAD-dependent epimerase/dehydratase; n=...    43   0.009
UniRef50_Q93VR3 Cluster: GDP-mannose 3,5-epimerase; n=21; cellul...    43   0.009
UniRef50_Q868I5 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=...    42   0.011
UniRef50_Q97KX2 Cluster: Nucleoside-diphosphate-sugar epimerase;...    42   0.015
UniRef50_Q67KU6 Cluster: UDP-glucose 4-epimerase; n=1; Symbiobac...    42   0.015
UniRef50_Q9JRN7 Cluster: Putative uncharacterized protein; n=1; ...    42   0.015
UniRef50_A1Y020 Cluster: UDP-glucose 4-epimerase; n=1; Spironucl...    42   0.015
UniRef50_Q9LIS3 Cluster: UDP-glucuronate 4-epimerase 6; n=40; Vi...    42   0.015
UniRef50_Q2WB63 Cluster: Nucleoside-diphosphate-sugar epimerase;...    42   0.020
UniRef50_Q7D561 Cluster: NAD-dependent epimerase/dehydratase fam...    42   0.020
UniRef50_Q1FJC1 Cluster: DTDP-glucose 4,6-dehydratase; n=1; Clos...    42   0.020
UniRef50_Q11WU7 Cluster: UDP-galactose-4-epimerase; n=1; Cytopha...    42   0.020
UniRef50_Q0YI68 Cluster: NAD-dependent epimerase/dehydratase:Sho...    42   0.020
UniRef50_Q0BRM8 Cluster: UDP-glucose 4-epimerase; n=2; Rhodospir...    42   0.020
UniRef50_Q2MFR9 Cluster: Putative NDP-(Heptose/hexose) epimerase...    41   0.027
UniRef50_A1VG42 Cluster: NAD-dependent epimerase/dehydratase; n=...    41   0.027
UniRef50_A0UW76 Cluster: NAD-dependent epimerase/dehydratase; n=...    41   0.027
UniRef50_Q88XK0 Cluster: UDP-glucose 4-epimerase; n=2; Lactobaci...    41   0.035
UniRef50_Q5FRS4 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=...    41   0.035
UniRef50_Q9F8M7 Cluster: DTDP-glucose 4,6-dehydratase; n=2; Clos...    41   0.035
UniRef50_A6QAJ4 Cluster: dTDP-glucose 4,6-dehydratase; n=1; Sulf...    41   0.035
UniRef50_Q7UVP4 Cluster: DTDP-glucose-4,6-dehydratase; n=1; Pire...    40   0.046
UniRef50_Q6EB26 Cluster: Tgh114; n=10; Bacteria|Rep: Tgh114 - Ca...    40   0.046
UniRef50_Q1Q482 Cluster: Similar to dTDP-glucose 4,6-dehydratase...    40   0.061
UniRef50_Q81AP5 Cluster: CDP-abequose synthase; n=2; Bacillus ce...    40   0.081
UniRef50_Q1YMT2 Cluster: UDP-glucose 4-epimerase; n=3; Alphaprot...    40   0.081
UniRef50_A6GE58 Cluster: NAD-dependent epimerase/dehydratase fam...    40   0.081
UniRef50_A6DF55 Cluster: Putative uncharacterized protein; n=1; ...    40   0.081
UniRef50_A5M424 Cluster: UDP-glucose 4-epimerase; n=1; Streptoco...    40   0.081
UniRef50_Q8ECF4 Cluster: DTDP-glucose 4,6-dehydratase; n=18; Gam...    39   0.11 
UniRef50_Q2WB32 Cluster: Nucleoside-diphosphate-sugar epimerase;...    39   0.11 
UniRef50_Q54WS6 Cluster: Putative dTDP-D-glucose 4,6-dehydratase...    39   0.11 
UniRef50_Q93KX6 Cluster: Putative UDP-glucose 4-epimerase; n=1; ...    39   0.14 
UniRef50_Q3E561 Cluster: NAD-dependent epimerase/dehydratase:Sho...    39   0.14 
UniRef50_Q1GKR7 Cluster: UDP-glucose 4-epimerase; n=17; Bacteria...    39   0.14 
UniRef50_Q42605 Cluster: UDP-glucose 4-epimerase; n=20; Viridipl...    39   0.14 
UniRef50_UPI0000DAE763 Cluster: hypothetical protein Rgryl_01001...    38   0.19 
UniRef50_Q9RSC3 Cluster: UDP-glucose 4-epimerase; n=1; Deinococc...    38   0.19 
UniRef50_Q8GP51 Cluster: Eps11G; n=11; Bacteria|Rep: Eps11G - St...    38   0.19 
UniRef50_A0UVI4 Cluster: NAD-dependent epimerase/dehydratase; n=...    38   0.19 
UniRef50_Q8WUS8 Cluster: HSPC105 protein; n=21; Euteleostomi|Rep...    38   0.19 
UniRef50_A5DWB0 Cluster: Putative uncharacterized protein; n=2; ...    38   0.19 
UniRef50_Q984R2 Cluster: DTDP-glucose 4-6-dehydratase; n=8; Prot...    38   0.25 
UniRef50_Q7WNH4 Cluster: Putative NAD dependent epimerase/dehydr...    38   0.25 
UniRef50_Q93KW6 Cluster: Putative NDP-glucose 4-epimerase; n=1; ...    38   0.25 
UniRef50_Q4HQ86 Cluster: UDP-glucose 4-epimerase, putative; n=2;...    38   0.25 
UniRef50_Q1QD53 Cluster: NAD-dependent epimerase/dehydratase; n=...    38   0.25 
UniRef50_Q58M85 Cluster: Nucleotide-sugar epimerase; n=1; Cyanop...    38   0.25 
UniRef50_Q8PXQ4 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=...    38   0.25 
UniRef50_O26473 Cluster: DTDP-glucose 4,6-dehydratase related pr...    38   0.25 
UniRef50_Q4K1T9 Cluster: Putative dehydratase/epimerase (Arabini...    38   0.33 
UniRef50_A7HBK8 Cluster: NAD-dependent epimerase/dehydratase; n=...    38   0.33 
UniRef50_A4BBD6 Cluster: Putative uncharacterized protein; n=1; ...    38   0.33 
UniRef50_Q96VM0 Cluster: Putative dTDP-glucose 4,6-dehydratase; ...    38   0.33 
UniRef50_A3H6D1 Cluster: NAD-dependent epimerase/dehydratase; n=...    38   0.33 
UniRef50_O95455 Cluster: dTDP-D-glucose 4,6-dehydratase; n=24; E...    38   0.33 
UniRef50_Q814Z6 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=...    37   0.43 
UniRef50_Q2JCE7 Cluster: DTDP-glucose 4,6-dehydratase; n=5; Bact...    37   0.43 
UniRef50_A6Q4T4 Cluster: NAD-dependent epimerase/dehydratase; n=...    37   0.43 
UniRef50_A4QBQ0 Cluster: Putative uncharacterized protein; n=1; ...    37   0.43 
UniRef50_P55295 Cluster: dTDP-glucose 4,6-dehydratase; n=185; Ba...    37   0.43 
UniRef50_Q59083 Cluster: UDP-glucose 4-epimerase; n=14; Bacteria...    37   0.43 
UniRef50_Q7CS52 Cluster: AGR_L_3011p; n=3; Alphaproteobacteria|R...    37   0.57 
UniRef50_Q2FA40 Cluster: DTDP-glucose 4-6-dehydratase; n=4; Bact...    37   0.57 
UniRef50_A6FPS1 Cluster: NAD-dependent epimerase/dehydratase; n=...    37   0.57 
UniRef50_A6SIX9 Cluster: Putative uncharacterized protein; n=1; ...    37   0.57 
UniRef50_O26480 Cluster: UDP-glucose 4-epimerase homolog; n=3; c...    37   0.57 
UniRef50_P14169 Cluster: CDP-paratose 2-epimerase; n=12; cellula...    37   0.57 
UniRef50_Q4AGU6 Cluster: NAD-dependent epimerase/dehydratase; n=...    36   0.76 
UniRef50_A3Q712 Cluster: UDP-glucose 4-epimerase; n=6; Actinobac...    36   0.76 
UniRef50_Q4CYB9 Cluster: GDP-mannose 4,6 dehydratase, putative; ...    36   0.76 
UniRef50_A2R6J0 Cluster: Catalytic activity: dTDPglucose = dTDP-...    36   0.76 
UniRef50_A1CX38 Cluster: Dtdp-glucose 4,6-dehydratase; n=6; Pezi...    36   0.76 
UniRef50_Q7UXZ2 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=...    36   1.00 
UniRef50_Q8U170 Cluster: UDP-or dTTP-glucose 4-epimerase or 4-6-...    36   1.00 
UniRef50_Q2NFA4 Cluster: Predicted dTDP-4-dehydrorhamnose reduct...    36   1.00 
UniRef50_Q4FRJ1 Cluster: LPS-assembly protein precursor; n=2; Ps...    36   1.00 
UniRef50_UPI0001597850 Cluster: hypothetical protein RBAM_031220...    36   1.3  
UniRef50_Q97L35 Cluster: FUSION: Nucleoside-diphosphate-sugar ep...    36   1.3  
UniRef50_A6BZU3 Cluster: Putative uncharacterized protein; n=1; ...    36   1.3  
UniRef50_Q0C425 Cluster: DTDP-glucose 4,6-dehydratase; n=4; Prot...    35   1.7  
UniRef50_A7HN54 Cluster: Polysaccharide biosynthesis protein Cap...    35   1.7  
UniRef50_A4FLF3 Cluster: NAD-dependent epimerase/dehydratase; n=...    35   1.7  
UniRef50_A3LR65 Cluster: Putative dtdp-glucose 4,6-dehydratase; ...    35   1.7  
UniRef50_Q6D795 Cluster: Putative dTDP-glucose 4-6-dehydratase; ...    35   2.3  
UniRef50_Q2JDH1 Cluster: NAD-dependent epimerase/dehydratase; n=...    35   2.3  
UniRef50_Q980W1 Cluster: UDP-glucose 4-epimerase; n=4; Sulfoloba...    35   2.3  
UniRef50_Q97A88 Cluster: DTDP-glucose 4,6-dehydratase; n=2; cell...    35   2.3  
UniRef50_Q8ZW82 Cluster: UDP-glucose 4-epimerase; n=6; Thermopro...    35   2.3  
UniRef50_Q5UYL1 Cluster: UDP-glucose 4-epimerase; n=5; Halobacte...    35   2.3  
UniRef50_P18645 Cluster: UDP-glucose 4-epimerase; n=353; cellula...    35   2.3  
UniRef50_Q1YQ08 Cluster: Oxidoreductase; n=1; gamma proteobacter...    34   3.0  
UniRef50_A7I3Y2 Cluster: Putative zinc protease; n=1; Campylobac...    34   3.0  
UniRef50_A0BCG5 Cluster: Chromosome undetermined scaffold_10, wh...    34   3.0  
UniRef50_Q9UXL5 Cluster: DTDP-glucose 4,6-dehydratase; n=1; Sulf...    34   3.0  
UniRef50_P44914 Cluster: dTDP-glucose 4,6-dehydratase; n=117; Ba...    34   3.0  
UniRef50_UPI00015BAE89 Cluster: NAD-dependent epimerase/dehydrat...    34   4.0  
UniRef50_Q8A3S4 Cluster: Putative nucleotide-sugar dehydratase; ...    34   4.0  
UniRef50_Q65D61 Cluster: Putative uncharacterized protein; n=1; ...    34   4.0  
UniRef50_Q1K169 Cluster: NAD-dependent epimerase/dehydratase; n=...    34   4.0  
UniRef50_A7HHX8 Cluster: NAD-dependent epimerase/dehydratase; n=...    34   4.0  
UniRef50_A3DIS0 Cluster: Polysaccharide biosynthesis protein Cap...    34   4.0  
UniRef50_A0L9M4 Cluster: NAD-dependent epimerase/dehydratase; n=...    34   4.0  
UniRef50_Q5DAK3 Cluster: SJCHGC01535 protein; n=2; Schistosoma j...    34   4.0  
UniRef50_Q7VRZ4 Cluster: Thymidine diphosphoglucose 4,6-dehydrat...    33   5.3  
UniRef50_Q7NRA0 Cluster: UDP-glucose 4-epimerase; n=1; Chromobac...    33   5.3  
UniRef50_Q1MP11 Cluster: Nucleoside-diphosphate-sugar epimerases...    33   5.3  
UniRef50_A3ZSY0 Cluster: CDP glucose 4,6-dehydratase; n=1; Blast...    33   5.3  
UniRef50_Q5UWG0 Cluster: UDP-glucose 4-epimerase; n=1; Haloarcul...    33   5.3  
UniRef50_Q8DGV6 Cluster: UDP-glucose 4-epimerase; n=1; Synechoco...    33   7.0  
UniRef50_Q2J7B4 Cluster: NAD-dependent epimerase/dehydratase; n=...    33   7.0  
UniRef50_Q2CH75 Cluster: DTDP-glucose 4,6-dehydratase; n=1; Ocea...    33   7.0  
UniRef50_Q1NXD3 Cluster: NAD-dependent epimerase/dehydratase:dTD...    33   7.0  
UniRef50_Q1MNV8 Cluster: Nucleoside-diphosphate-sugar epimerases...    33   7.0  
UniRef50_Q124Y5 Cluster: NAD-dependent epimerase/dehydratase; n=...    33   7.0  
UniRef50_Q0F315 Cluster: DTDP-D-glucose 4,6-dehydratase; n=3; Pr...    33   7.0  
UniRef50_A6H035 Cluster: GDP-4-dehydro-D-rhamnose reductase; n=1...    33   7.0  
UniRef50_A3CKR6 Cluster: Nucleoside-diphosphate-sugar epimerase,...    33   7.0  
UniRef50_Q2UMZ8 Cluster: Nucleoside-diphosphate-sugar epimerases...    33   7.0  
UniRef50_Q9HSU9 Cluster: GDP-D-mannose dehydratase; n=2; Halobac...    33   7.0  
UniRef50_Q18Z69 Cluster: CDP-glucose 4,6-dehydratase; n=1; Desul...    33   9.3  
UniRef50_Q9SGX0 Cluster: F1N19.2; n=1; Arabidopsis thaliana|Rep:...    33   9.3  
UniRef50_A7QYR5 Cluster: Chromosome chr5 scaffold_253, whole gen...    33   9.3  
UniRef50_A1RW61 Cluster: NAD-dependent epimerase/dehydratase; n=...    33   9.3  

>UniRef50_Q13630 Cluster: GDP-L-fucose synthetase (EC 1.1.1.271)
           (Protein FX) (Red cell NADP(H)- binding protein); n=59;
           Eukaryota|Rep: GDP-L-fucose synthetase (EC 1.1.1.271)
           (Protein FX) (Red cell NADP(H)- binding protein) - Homo
           sapiens (Human)
          Length = 321

 Score =  288 bits (707), Expect = 8e-77
 Identities = 134/216 (62%), Positives = 162/216 (75%)
 Frame = +3

Query: 3   SGLVGQAIKTVIERDRQKRNSDYDSETWIFSGSKDGDLRDKTQTEALFAKHKPTHVIHLA 182
           SGLVG+AI+ V+        +    E W+F  SKD DL D  QT ALF K +PTHVIHLA
Sbjct: 16  SGLVGKAIQKVVAD-----GAGLPGEDWVFVSSKDADLTDTAQTRALFEKVQPTHVIHLA 70

Query: 183 AMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETM 362
           AMVGGLF N+ +NLDF+R+N+ +NDN+L +  +   +KVVSCLSTCIFPDKTTYPIDETM
Sbjct: 71  AMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPIDETM 130

Query: 363 VHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESSHVIPA 542
           +HNGPPH+SNFGYSYAKRMIDV NR Y + YGC FT+VIP NVFGP+DNF++E  HV+P 
Sbjct: 131 IHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGPHDNFNIEDGHVLPG 190

Query: 543 LIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLAR 650
           LI ++  A   G    TV G+G P RQFIYSLDLA+
Sbjct: 191 LIHKVHLAKSSGS-ALTVWGTGNPRRQFIYSLDLAQ 225


>UniRef50_A5PHP4 Cluster: GDP-4-dehydro-6-deoxy-D-mannose
           epimerase/reductase; n=2; Trypanosoma brucei|Rep:
           GDP-4-dehydro-6-deoxy-D-mannose epimerase/reductase -
           Trypanosoma brucei brucei
          Length = 358

 Score =  263 bits (644), Expect = 3e-69
 Identities = 122/218 (55%), Positives = 158/218 (72%)
 Frame = +3

Query: 3   SGLVGQAIKTVIERDRQKRNSDYDSETWIFSGSKDGDLRDKTQTEALFAKHKPTHVIHLA 182
           +GLVG+A++ V      KRN+  D E W+F    D DLR    T  +F +HKPTHV+HLA
Sbjct: 54  AGLVGRAVEVVT-----KRNACAD-ERWVFLSRHDADLRSMAATRCVFERHKPTHVLHLA 107

Query: 183 AMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETM 362
           A VGGLF NMA  ++ + +N+SIN+N+L+ C  Y V+K VSCLSTCIFP++ TYPI E  
Sbjct: 108 ARVGGLFKNMAAPVEMWIDNVSINNNVLECCRTYGVRKAVSCLSTCIFPERATYPIGEET 167

Query: 363 VHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESSHVIPA 542
           +H+GPPH SN  Y+YAKRMIDVLNR YN+ YGC FTSVIP NV+GP+DN++L+ SHVIP 
Sbjct: 168 LHDGPPHYSNEQYAYAKRMIDVLNRAYNKEYGCRFTSVIPTNVYGPHDNYNLQDSHVIPG 227

Query: 543 LIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAV 656
           LI +   A ++  P   VMG+G+PLRQF+YS DLA  +
Sbjct: 228 LIHKFYLAKRENKP-MVVMGTGRPLRQFVYSEDLAELI 264


>UniRef50_Q00XZ4 Cluster: GDP-4-keto-6-deoxy-D-mannose
           epimerase-reductase; n=1; Ostreococcus tauri|Rep:
           GDP-4-keto-6-deoxy-D-mannose epimerase-reductase -
           Ostreococcus tauri
          Length = 252

 Score =  233 bits (571), Expect = 2e-60
 Identities = 122/219 (55%), Positives = 146/219 (66%), Gaps = 35/219 (15%)
 Frame = +3

Query: 99  SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMA--------------------- 215
           S+D +L D   T A+F K+KPTHVIHLAA VGGLF NM                      
Sbjct: 14  SQDANLCDPESTAAMFDKYKPTHVIHLAAQVGGLFANMVRAKRRERSNRIATDIRAFVFP 73

Query: 216 ---HNLDFFRENMSINDNILQACHKYN-----------VKKVVSCLSTCIFPDKTTYPID 353
              + ++F+R N+++NDNI Q CHK             V+K+VSCLSTCIFPDKTT+PID
Sbjct: 74  PQKYKVEFWRNNIAMNDNIFQECHKRGTLAWIAINITRVQKLVSCLSTCIFPDKTTFPID 133

Query: 354 ETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESSHV 533
           ETM+HNGPPH SN GY+YAKRM+DV NR Y   +GC FT+VIP N+FG +DNF L+ SHV
Sbjct: 134 ETMIHNGPPHFSNEGYAYAKRMVDVQNRMYKAQHGCNFTAVIPTNIFGKHDNFHLDDSHV 193

Query: 534 IPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLAR 650
           IP LI R     QKG+P FT+ GSGKPLRQFIYS DLAR
Sbjct: 194 IPGLIHRGYLCKQKGEP-FTIWGSGKPLRQFIYSTDLAR 231


>UniRef50_Q8IJQ5 Cluster: GDP-fucose synthase, putative; n=5;
           Plasmodium|Rep: GDP-fucose synthase, putative -
           Plasmodium falciparum (isolate 3D7)
          Length = 329

 Score =  176 bits (428), Expect = 5e-43
 Identities = 84/215 (39%), Positives = 138/215 (64%), Gaps = 4/215 (1%)
 Frame = +3

Query: 27  KTVIERDRQ---KRNSDYDSET-WIFSGSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVG 194
           K +IE++ +     N + +  T +IF  S+  DL+D  +++ +F K+  T +IH AA VG
Sbjct: 27  KNIIEKENEIIVNSNENKNIITKYIFLSSEMCDLKDYDKSKLVFEKYNFTDIIHFAAHVG 86

Query: 195 GLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNG 374
           GL+ N  +NLDF   N+ I+ N+++ CHKY++ + +  LSTCIFP   + P+ E  +H+G
Sbjct: 87  GLYANKNNNLDFLINNLEISMNVIKLCHKYSISRGIFTLSTCIFPVNCSLPLTEEKIHDG 146

Query: 375 PPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRR 554
             H SN GYS +KR+++VL R Y E Y   +  +IP N++G YDNF+LE++HVIP++I +
Sbjct: 147 KCHQSNEGYSVSKRVLEVLVRFYREKYNYEWICIIPTNIYGKYDNFNLENAHVIPSIIHK 206

Query: 555 MDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAVH 659
           M  A       + ++G G  +RQFIY++D+ + ++
Sbjct: 207 MYLAKVNNTNVY-LLGDGSAVRQFIYNIDVNKILY 240


>UniRef50_Q74FI1 Cluster: GDP-fucose synthetase; n=7; Bacteria|Rep:
           GDP-fucose synthetase - Geobacter sulfurreducens
          Length = 314

 Score =  150 bits (364), Expect = 3e-35
 Identities = 75/181 (41%), Positives = 106/181 (58%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           DLRD+    A FA  +P +V   AA VGG+  N  +  +F  +N+ I  N++ + ++  V
Sbjct: 41  DLRDQAAVAAFFAAEQPDYVFLAAAKVGGIVANNTYPAEFIYDNLMIEANVIHSSYRTGV 100

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 470
            K++   STCI+P   + PI E  +  GP   +N  Y+ AK     L R YN  YG  F 
Sbjct: 101 SKLLFLGSTCIYPKMASQPIREEYLLTGPLEPTNEAYAIAKIAGISLCRSYNRQYGTRFI 160

Query: 471 SVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLAR 650
           + +P N++GP DNF LE SHV+PALIR+  +A   G PT TV G+G PLR+FI+  D+A 
Sbjct: 161 AAMPTNLYGPNDNFDLEKSHVLPALIRKFHEAKIAGAPTVTVWGTGAPLREFIHVDDVAD 220

Query: 651 A 653
           A
Sbjct: 221 A 221


>UniRef50_Q0BHR7 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Burkholderia ambifaria AMMD|Rep: NAD-dependent
           epimerase/dehydratase - Burkholderia cepacia (strain
           ATCC 53795 / AMMD)
          Length = 311

 Score =  136 bits (330), Expect = 4e-31
 Identities = 80/234 (34%), Positives = 127/234 (54%)
 Frame = +3

Query: 6   GLVGQAIKTVIERDRQKRNSDYDSETWIFSGSKDGDLRDKTQTEALFAKHKPTHVIHLAA 185
           G++G A+K      ++  +S Y +   I S   D DLRD++ TE +F + +PT V H+AA
Sbjct: 15  GVIGHALK------QELADSGYSNVVAITSS--DIDLRDQSATEKMFDELRPTIVFHMAA 66

Query: 186 MVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMV 365
            V G+  NM++    + +N+ IN N+++A  +   KK V+  ST I+ D+   P+ E  +
Sbjct: 67  RVYGIMGNMSNRGIAYLDNVRINTNVVEAARQTGCKKFVAMGSTAIYSDQVRLPMSEEQI 126

Query: 366 HNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESSHVIPAL 545
             G PH S   Y+++KR +      Y + YG  +   +  N+FGP+D F  +  HVIP+L
Sbjct: 127 WVGAPHHSEAPYAHSKRGMLAQLEAYKDQYGMDYAFCVSTNLFGPHDKFDEKFGHVIPSL 186

Query: 546 IRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAVHLGSSGTTTVSNLLSYQ 707
           + +   A   G P  +V GSGK  R F++S D A A+ L +   T   NL + Q
Sbjct: 187 VSKFYRASVLGQP-ISVWGSGKAERDFLFSGDAAYALRLIAENHTGAINLATGQ 239


>UniRef50_Q2RXT6 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           Proteobacteria|Rep: NAD-dependent epimerase/dehydratase
           - Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255)
          Length = 329

 Score =  134 bits (324), Expect = 2e-30
 Identities = 67/187 (35%), Positives = 107/187 (57%)
 Frame = +3

Query: 96  GSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQAC 275
           G +D DL  +   EA    ++P  V+  AA+VGG+  N   + +F  +N+++  NI+ A 
Sbjct: 52  GREDLDLTRQQAVEAWMEANRPDAVVMAAALVGGIKANDRRSAEFIHQNLAVQTNIIHAA 111

Query: 276 HKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESY 455
            +  V KV+   S+CI+P     P+ E  + +GP   +N  Y+ AK     + + Y   Y
Sbjct: 112 WQAGVGKVLFLGSSCIYPRDVAQPMREDALLSGPLEPTNQWYAIAKIAGIRMAQAYRRQY 171

Query: 456 GCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYS 635
           GC + S +P N++GP DNF L+  HV+PAL+R++ +A  +G     + GSG PLR+F+Y 
Sbjct: 172 GCDYISAMPTNLYGPGDNFDLDGGHVLPALLRKIHEAKVEGRGEVVLWGSGAPLREFLYV 231

Query: 636 LDLARAV 656
            DLA A+
Sbjct: 232 DDLADAL 238


>UniRef50_Q3B1R9 Cluster: GDP-L-fucose synthetase; n=3;
           Bacteria|Rep: GDP-L-fucose synthetase - Pelodictyon
           luteolum (strain DSM 273) (Chlorobium luteolum (strain
           DSM273))
          Length = 319

 Score =  133 bits (322), Expect = 4e-30
 Identities = 69/185 (37%), Positives = 105/185 (56%), Gaps = 1/185 (0%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           DL ++   +  F+  KP  V   AA VGG+  N  +  +F  +N+ +  N++ A ++  V
Sbjct: 41  DLTNQAAVQDFFSTEKPDQVYLAAAKVGGIHANNTYPAEFIYQNLMVECNVIDAAYRNGV 100

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 470
           +K++   S+CI+P +   P+ E  +  G    +N  Y+ AK     L   YN  YG  + 
Sbjct: 101 EKLLFLGSSCIYPKQAPQPMRENALLTGVLEPTNEPYAIAKIAGIKLCESYNRQYGTDYR 160

Query: 471 SVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLAR 650
           SV+P N++GP DN+  E+SHVIPALIRR  +A     PT T+ GSG P R+F+Y  D+A 
Sbjct: 161 SVMPTNLYGPGDNYHPENSHVIPALIRRFHEATVGNAPTVTIWGSGTPRREFLYVDDMAA 220

Query: 651 A-VHL 662
           A VH+
Sbjct: 221 ASVHV 225


>UniRef50_Q2IZX2 Cluster: NAD-dependent epimerase/dehydratase; n=4;
           Alphaproteobacteria|Rep: NAD-dependent
           epimerase/dehydratase - Rhodopseudomonas palustris
           (strain HaA2)
          Length = 337

 Score =  132 bits (320), Expect = 6e-30
 Identities = 68/187 (36%), Positives = 103/187 (55%)
 Frame = +3

Query: 96  GSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQAC 275
           G  + DLR +T+ +  F+  +P  VI  AA VGG+  N  +   F  +N+SI DN++Q+ 
Sbjct: 41  GRDELDLRHQTKVQEWFSSERPDVVILAAARVGGVLANSKYPASFLSDNLSIQDNVIQSA 100

Query: 276 HKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESY 455
               VKK++   S+C++P   + PI+E  +  G    +N  Y  AK    +    Y E Y
Sbjct: 101 AAAGVKKLLFVSSSCVYPRLASQPIEEDALLTGALEPTNRWYGVAKIAGMMQCAAYREQY 160

Query: 456 GCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYS 635
           GC F + +P N++GP D F  E+SHVIPA +RR  DA+  G     V GSG   R+F++ 
Sbjct: 161 GCDFIAAVPGNLYGPGDYFDKENSHVIPAFLRRFHDAVTTGADEVAVWGSGTARREFVFV 220

Query: 636 LDLARAV 656
            + A A+
Sbjct: 221 DECADAL 227


>UniRef50_Q0M6J4 Cluster: NAD-dependent epimerase/dehydratase:3-beta
           hydroxysteroid
           dehydrogenase/isomerase:dTDP-4-dehydrorhamnose
           reductase:Male sterility-like; n=1; Caulobacter sp.
           K31|Rep: NAD-dependent epimerase/dehydratase:3-beta
           hydroxysteroid
           dehydrogenase/isomerase:dTDP-4-dehydrorhamnose
           reductase:Male sterility-like - Caulobacter sp. K31
          Length = 316

 Score =  132 bits (318), Expect = 1e-29
 Identities = 68/186 (36%), Positives = 100/186 (53%)
 Frame = +3

Query: 99  SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACH 278
           S DGDL     T AL  + +P  VIHLAA  GG+  N +   DF+  N+++  N+ +A  
Sbjct: 36  SADGDLTSFDVTRALLERVRPDAVIHLAAYSGGIGANRSWPADFYWRNITLVSNMYEAAA 95

Query: 279 KYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 458
           +  VK++V  +  C +P   T PI E  +  G P   +  YS AK+M  V  + Y   +G
Sbjct: 96  QTGVKRIVYTMGGCSYPGTATSPISEDQMWEGYPQGDSAAYSAAKKMGIVAAKAYEAQHG 155

Query: 459 CMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSL 638
              T ++P N+FG +DN+    SHVIPA +RR  +A   G    T  G G   R F+Y+ 
Sbjct: 156 ISSTVLVPGNLFGEFDNYRNGESHVIPAFLRRFHEAKLNGVTEVTCWGRGIAQRDFVYAE 215

Query: 639 DLARAV 656
           D+A+A+
Sbjct: 216 DVAKAI 221


>UniRef50_Q93N55 Cluster: GDP-4-keto-6 deoxymannose
           epimerase/reductase; n=2; Coxiella burnetii|Rep:
           GDP-4-keto-6 deoxymannose epimerase/reductase - Coxiella
           burnetii
          Length = 332

 Score =  130 bits (313), Expect = 4e-29
 Identities = 65/181 (35%), Positives = 103/181 (56%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           DL +K +    FA + P +V   AA VGG+  +  H +DF R+N++I  N+++A  +Y V
Sbjct: 41  DLTNKEKVFEFFANNCPEYVFLAAARVGGINDSNLHPVDFIRDNLAIQWNVIEASFRYKV 100

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 470
           K+++   S+CI+ +    P+ E   ++G    +N  YS AK         YN  Y   + 
Sbjct: 101 KRLLFLGSSCIYSNDAPRPLKEIYFNSGKLEPTNRAYSTAKIAGIEHCWAYNRQYKTQYL 160

Query: 471 SVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLAR 650
             +P N+FGP DN+ LE+ HV+ +LI ++  A ++  P F + GSGK  R+F+YS DLA 
Sbjct: 161 CAMPTNLFGPNDNYDLENGHVVASLISKIHQAKEQKKPNFVLWGSGKAKREFLYSDDLAE 220

Query: 651 A 653
           A
Sbjct: 221 A 221


>UniRef50_Q5V3C6 Cluster: DTDP-glucose dehydratase; n=23; cellular
           organisms|Rep: DTDP-glucose dehydratase - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 333

 Score =  130 bits (313), Expect = 4e-29
 Identities = 62/186 (33%), Positives = 104/186 (55%)
 Frame = +3

Query: 99  SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACH 278
           S + DLR++T     F +     V+HLAA VGG+  N  +   +F +N  +   +L+   
Sbjct: 49  SNEYDLRERTDIRRAFTQSGADVVVHLAATVGGIGANRENPGRYFYDNAIMGIELLEMAR 108

Query: 279 KYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 458
           +++V K     + C +P+ T  P  E  + +G P  +N  Y  AK+ +   +R Y + Y 
Sbjct: 109 QFDVDKFTILGTICSYPNHTEVPFSEDDLFDGYPEETNAPYGIAKKALLTQSRAYRKQYD 168

Query: 459 CMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSL 638
                ++P N++GP D+F L S+HVIPA+IR+  +A ++GD + T  G+G+P R+F+Y  
Sbjct: 169 FNSIYLMPVNLYGPRDDFDLHSAHVIPAIIRKCIEARERGDDSITAWGTGEPTREFLYVK 228

Query: 639 DLARAV 656
           D AR +
Sbjct: 229 DAARGI 234


>UniRef50_A4YQ54 Cluster: Bifunctional GDP-fucose synthetase:
           GDP-4-dehydro-6-deoxy-D-mannose epimerase;
           GDP-4-dehydro-6-L-deoxygalactose reductase; n=17;
           root|Rep: Bifunctional GDP-fucose synthetase:
           GDP-4-dehydro-6-deoxy-D-mannose epimerase;
           GDP-4-dehydro-6-L-deoxygalactose reductase -
           Bradyrhizobium sp. (strain ORS278)
          Length = 318

 Score =  129 bits (311), Expect = 8e-29
 Identities = 71/185 (38%), Positives = 101/185 (54%), Gaps = 1/185 (0%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           DL D+    A FA+ KP  V   AA VGG+  N     +F  +N++I  N++ A H   V
Sbjct: 46  DLSDQAAVFAWFARAKPQVVFLAAAKVGGIVANNTLRAEFIYDNIAIATNVIHAAHVNGV 105

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 470
           +K++   S+CI+P     P+ E  +  GP   +N  Y+ AK     +   Y   YG  F 
Sbjct: 106 EKLMFLGSSCIYPKLAAQPLREDAMLTGPLEPTNEPYAIAKIAGIKMVEAYRSQYGADFI 165

Query: 471 SVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLAR 650
           +V+P N++GP DN+  E SHV+ ALIRR  +A     P   V G+GKP R+F+Y  D+A 
Sbjct: 166 NVMPTNLYGPGDNYHPEYSHVVAALIRRFHEAKLADAPEVIVWGTGKPRREFLYVDDMAD 225

Query: 651 A-VHL 662
           A VHL
Sbjct: 226 ACVHL 230


>UniRef50_Q124Z8 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           Betaproteobacteria|Rep: NAD-dependent
           epimerase/dehydratase - Polaromonas sp. (strain JS666 /
           ATCC BAA-500)
          Length = 331

 Score =  125 bits (302), Expect = 1e-27
 Identities = 63/190 (33%), Positives = 99/190 (52%)
 Frame = +3

Query: 87  IFSGSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNIL 266
           + +  ++ DL D++       +++P  + H+ A VGG+  N     DF   N+ I  N++
Sbjct: 47  LLTSRQELDLSDQSAVFNWVDENRPELIFHVGAKVGGIHANSTLPADFLYSNLMIQSNVI 106

Query: 267 QACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYN 446
            A H +  KK+V   S C +P KT  PI E  +  GP   +   Y+ +K     + R Y 
Sbjct: 107 NAAHLFGAKKLVFVASNCTYPTKTAQPIPEEALMTGPLDENIRAYAISKIAGIEMCRAYR 166

Query: 447 ESYGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQF 626
           + YG  F SVIP N++GP DN+  + SHV+  ++RR  +A   G   F V G G P R+ 
Sbjct: 167 KQYGSNFISVIPPNLYGPGDNYHPQHSHVVAGILRRTHEAKLAGKSEFVVWGDGTPRREL 226

Query: 627 IYSLDLARAV 656
           ++  DLA A+
Sbjct: 227 LHVDDLADAM 236


>UniRef50_A7IWS0 Cluster: Putative uncharacterized protein B395L;
           n=3; Chlorovirus|Rep: Putative uncharacterized protein
           B395L - Paramecium bursaria Chlorella virus NY2A
           (PBCV-NY2A)
          Length = 320

 Score =  124 bits (300), Expect = 2e-27
 Identities = 66/186 (35%), Positives = 99/186 (53%)
 Frame = +3

Query: 99  SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACH 278
           SKD DL ++ +  A F    P +V   AA VGG+  N +   DF  +N+ I  N++ A  
Sbjct: 37  SKDLDLTNQREVNAFFEIELPEYVFLAAAKVGGIHANNSFGGDFIHDNLMIQTNVIHASK 96

Query: 279 KYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 458
            + VKK+V   S+CI+P +   PI E  +  G    +N  Y+ AK     +   Y + YG
Sbjct: 97  MFGVKKLVFLGSSCIYPKEAQNPIKEEYLMTGFLEPTNKPYAIAKIAGIEMCDAYRKQYG 156

Query: 459 CMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSL 638
           C F SV+P N+ GP D + L + HV P LIR+  +A     P+  + G+G   R+F++  
Sbjct: 157 CNFVSVMPTNLSGPNDRYDLNNGHVFPVLIRKFCEAKVHNVPSVKLWGTGIARREFLHVD 216

Query: 639 DLARAV 656
           DLAR +
Sbjct: 217 DLARGI 222


>UniRef50_O49213 Cluster: GDP-L-fucose synthase 1; n=181; root|Rep:
           GDP-L-fucose synthase 1 - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 312

 Score =  123 bits (296), Expect = 5e-27
 Identities = 65/181 (35%), Positives = 100/181 (55%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           DL  +   E+ F++ KP +VI  AA VGG+  N  +  DF   N+ I  N++ + +++ V
Sbjct: 42  DLTRQADVESFFSQEKPVYVILAAAKVGGIHANNTYPADFIGVNLQIQTNVIHSAYEHGV 101

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 470
           KK++   S+CI+P     PI E+ +       +N  Y+ AK       + Y   +G    
Sbjct: 102 KKLLFLGSSCIYPKFAPQPIPESALLTASLEPTNEWYAIAKIAGIKTCQAYRIQHGWDAI 161

Query: 471 SVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLAR 650
           S +P N++GP DNF  E+SHV+PAL+RR  +A   G     V G+G PLR+F++  DLA 
Sbjct: 162 SGMPTNLYGPNDNFHPENSHVLPALMRRFHEAKVNGAEEVVVWGTGSPLREFLHVDDLAD 221

Query: 651 A 653
           A
Sbjct: 222 A 222


>UniRef50_A6VG32 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Methanococcus maripaludis C7|Rep: NAD-dependent
           epimerase/dehydratase - Methanococcus maripaludis C7
          Length = 307

 Score =  121 bits (291), Expect = 2e-26
 Identities = 75/218 (34%), Positives = 109/218 (50%), Gaps = 1/218 (0%)
 Frame = +3

Query: 3   SGLVGQAIKTVIERDRQKRNSDYDSETWIFSGSKDGDLRDKTQTEALFAKHKPTHVIHLA 182
           SGLVG +I       RQ     Y +    +  SK  +L DK Q E      KP ++  +A
Sbjct: 13  SGLVGSSIF------RQLSKKGYSNVN--YPSSKSVNLLDKNQVEEYIKSEKPEYLFMVA 64

Query: 183 AMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVK-KVVSCLSTCIFPDKTTYPIDET 359
            +VGG++ NM  N DF  +N  +  N+L++    +   K++   STCI+P +   PI E 
Sbjct: 65  GLVGGIYGNMKRNADFLYQNSIMILNVLESIKNCSKDTKILYTGSTCIYPKENPQPISEN 124

Query: 360 MVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESSHVIP 539
            + NG    SN GY+ AK +  V    Y + YG     V+P N++GP D + LE  H IP
Sbjct: 125 RLLNGLLEESNKGYALAKILGIVGCELYKKQYGINSICVMPTNMYGPNDTYDLEDGHFIP 184

Query: 540 ALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARA 653
           +LI++  DA        T  G+G P R+ +Y  D A A
Sbjct: 185 SLIKKFVDAKNNNLKELTFWGTGIPRREALYVDDCADA 222


>UniRef50_Q0EXY2 Cluster: GDP-fucose synthetase; n=4;
           Proteobacteria|Rep: GDP-fucose synthetase -
           Mariprofundus ferrooxydans PV-1
          Length = 371

 Score =  120 bits (288), Expect = 5e-26
 Identities = 68/194 (35%), Positives = 106/194 (54%), Gaps = 2/194 (1%)
 Frame = +3

Query: 6   GLVGQAIKTVIERDRQKRNSDYDSETWIFSGSKDGDLRDKTQTEALFAKHKPTHVIHLAA 185
           GLVG AI       R+   + +  E+ +   S + DLR++   +A FA  +P +V   AA
Sbjct: 28  GLVGSAIV------RKLLAAGHSPESLVLRTSSELDLRNQAAVDAFFALERPEYVFLAAA 81

Query: 186 MVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMV 365
            VGG++ N  +  DF R+N+ I  N++ A +   VK+++   S+CI+P     P+ E+ +
Sbjct: 82  KVGGIYANDTYPADFIRDNLQIQTNVIDAAYSNGVKRLLFLGSSCIYPKLAPQPMPESCL 141

Query: 366 HNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESSHVIPAL 545
             G    +N  Y+ AK     + + Y++ YG    S +P N++GP DNF LE SHV+PAL
Sbjct: 142 LTGELEPTNEWYAIAKIAGIKMCQAYHKQYGFDAISAMPTNLYGPNDNFDLEKSHVLPAL 201

Query: 546 IRRMDDA--MQKGD 581
           IR+   A   Q GD
Sbjct: 202 IRKFHLAKLAQAGD 215


>UniRef50_Q7BR89 Cluster: GDP-6-deoxy-4-keto-D-mannose-3,
           5-epimerase-4-reductase merA; n=4; Mycobacterium
           avium|Rep: GDP-6-deoxy-4-keto-D-mannose-3,
           5-epimerase-4-reductase merA - Mycobacterium avium
          Length = 339

 Score =  119 bits (287), Expect = 6e-26
 Identities = 64/181 (35%), Positives = 96/181 (53%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           DL D+  T    ++ +P  +I  AA VGG+  N  +  DF  EN+ I  N+L A     V
Sbjct: 67  DLTDRAATFDFVSETRPQVIIDAAARVGGIMANNTYPADFLSENLRIQTNLLDAAVAVRV 126

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 470
            +++   S+CI+P     PI E+ +  GP   +N  Y+ AK    +  +     YG  + 
Sbjct: 127 PRLLFLGSSCIYPKYAPQPIHESALLTGPLEPTNDAYAIAKIAGILQVQAVRRQYGLAWI 186

Query: 471 SVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLAR 650
           S +P N++GP DNFS   SH++PALIRR ++A   G    T  G+G P R+ ++  DLA 
Sbjct: 187 SAMPTNLYGPGDNFSPSGSHLLPALIRRYEEAKAGGAEEVTNWGTGTPRRELLHVDDLAS 246

Query: 651 A 653
           A
Sbjct: 247 A 247


>UniRef50_Q4AI76 Cluster: GDP-L-fucose synthase; n=6; Bacteria|Rep:
           GDP-L-fucose synthase - Chlorobium phaeobacteroides BS1
          Length = 402

 Score =  118 bits (284), Expect = 1e-25
 Identities = 59/149 (39%), Positives = 86/149 (57%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           DLR+    +  F + KP +VI  AA VGG+  N  +  DF  EN+ I  N++   +   V
Sbjct: 41  DLRNTMAVKTFFEREKPEYVILAAAKVGGIVANNTYRADFIYENLMIQSNVIHQSYLSGV 100

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 470
           KK++   STCI+P +   P+ E  +   P   +N  Y+ AK     +   YN  YG  F 
Sbjct: 101 KKLLFLGSTCIYPKECPQPMKEEHLLTSPLEYTNEPYAIAKIAGIKMCESYNIQYGTNFI 160

Query: 471 SVIPCNVFGPYDNFSLESSHVIPALIRRM 557
           SV+P N++GP DNF+LE+SHV+PALIR++
Sbjct: 161 SVMPTNLYGPNDNFNLETSHVLPALIRKI 189


>UniRef50_Q1VHC4 Cluster: GDP-fucose synthetase chain A; n=1;
           Psychroflexus torquis ATCC 700755|Rep: GDP-fucose
           synthetase chain A - Psychroflexus torquis ATCC 700755
          Length = 311

 Score =  117 bits (282), Expect = 3e-25
 Identities = 63/190 (33%), Positives = 100/190 (52%)
 Frame = +3

Query: 87  IFSGSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNIL 266
           I    K  +L D+ +T     K KP  VI  AA VGG+  NM     F  EN+ I +NI+
Sbjct: 35  IIEDKKKLNLLDQNKTFKFLEKKKPDFVIIAAARVGGIVANMKFKSKFIYENLQIQNNII 94

Query: 267 QACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYN 446
              +   VK +    S+CI+P  +  P+ E  + +GP   +N  Y+ AK     +   Y+
Sbjct: 95  HGSYLAGVKNLFLLGSSCIYPKFSKQPMKEKYLLSGPLEETNDAYAIAKIAGIKMCENYS 154

Query: 447 ESYGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQF 626
           +++   F S++P N++GP DN+ L +SH  PAL++++  A  +    F + GSGK  R+ 
Sbjct: 155 KNFNLNFKSLMPPNLYGPNDNYDLSNSHFYPALLKKIHTAKIQNKKNFLIWGSGKAKREL 214

Query: 627 IYSLDLARAV 656
           ++  D A AV
Sbjct: 215 MFVDDFADAV 224


>UniRef50_A5ZJL9 Cluster: Putative uncharacterized protein; n=1;
           Bacteroides caccae ATCC 43185|Rep: Putative
           uncharacterized protein - Bacteroides caccae ATCC 43185
          Length = 358

 Score =  111 bits (266), Expect(2) = 4e-25
 Identities = 57/162 (35%), Positives = 91/162 (56%), Gaps = 2/162 (1%)
 Frame = +3

Query: 102 KDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHK 281
           K+ DL D    +  F +  P  V+  AA VGG+  N+ +  DF  +N+ I  N++    +
Sbjct: 38  KELDLLDGVAVKQFFDEELPDAVVLAAAHVGGIMANLQYRADFIYQNLQIQQNVIGESFR 97

Query: 282 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 461
           +NVKK++   STCI+P     P+ E  +   P   +N  Y+ AK     +   +N  YG 
Sbjct: 98  HNVKKLLFLGSTCIYPRDVAQPMKEDALLTSPLEYTNEPYAIAKIAGLKMCESFNLQYGT 157

Query: 462 MFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDA--MQKGD 581
            + +V+P N++GP DNF LE+SHV+PA+IR++  A  + +GD
Sbjct: 158 NYIAVMPTNLYGPNDNFHLENSHVLPAMIRKIHLAKCLNEGD 199



 Score = 26.6 bits (56), Expect(2) = 4e-25
 Identities = 11/25 (44%), Positives = 20/25 (80%), Gaps = 1/25 (4%)
 Frame = +3

Query: 591 TVMGSGKPLRQFIYSLDLARA-VHL 662
           T+ G+G P+R+F++S ++A A VH+
Sbjct: 239 TLWGTGTPMREFLWSEEMADASVHV 263


>UniRef50_Q8VU14 Cluster: GDP-4-keto-6-deoxy-D-mannose-3,
           5-epimerase-4-reductase; n=32; Bacteria|Rep:
           GDP-4-keto-6-deoxy-D-mannose-3, 5-epimerase-4-reductase
           - Bacteroides fragilis
          Length = 360

 Score =  110 bits (265), Expect(2) = 5e-25
 Identities = 57/162 (35%), Positives = 90/162 (55%), Gaps = 2/162 (1%)
 Frame = +3

Query: 102 KDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHK 281
           K+ DL D    +  F +  P +V   AA VGG+  N  +  DF  +N+ I  N++    +
Sbjct: 42  KELDLLDGATVKQFFDEEMPEYVFLAAAFVGGIMANSIYRADFIYKNLQIQQNVIGESFR 101

Query: 282 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 461
           + VKK++   STCI+P     P+ E ++   P   +N  Y+ AK     +   +N  YG 
Sbjct: 102 HQVKKLLFLGSTCIYPRDAEQPMKEDVLLTSPLEYTNEPYAIAKIAGLKMCESFNLQYGT 161

Query: 462 MFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDA--MQKGD 581
            + +V+P N++GP DNF LE SHV+PA+IR++  A  ++KGD
Sbjct: 162 NYIAVMPTNLYGPNDNFDLERSHVLPAMIRKVHLAHCLKKGD 203



 Score = 26.6 bits (56), Expect(2) = 5e-25
 Identities = 10/21 (47%), Positives = 17/21 (80%)
 Frame = +3

Query: 591 TVMGSGKPLRQFIYSLDLARA 653
           T+ G+G PLR+F++S ++A A
Sbjct: 243 TLWGTGTPLREFLWSEEMADA 263


>UniRef50_A5GHX4 Cluster: GDP-L fucose synthetase; n=25;
           Bacteria|Rep: GDP-L fucose synthetase - Synechococcus
           sp. (strain WH7803)
          Length = 343

 Score =  115 bits (276), Expect = 1e-24
 Identities = 63/194 (32%), Positives = 101/194 (52%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           DL D +         +P  V+  AA VGG+  N +   DF  +N+ I   +++A  +  V
Sbjct: 53  DLLDDSAVRDWMEAQRPDVVVLAAATVGGIEANRSRPADFLLQNLRIETQVIEAAWRCGV 112

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 470
           ++++   S+CI+P     PI E  +  G    +N  Y+ AK     L       +G    
Sbjct: 113 RRLLFLGSSCIYPKFADQPIREEALLTGALEPTNAWYAIAKIAGIKLAEALRLQHGFDAI 172

Query: 471 SVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLAR 650
           S++P N++GP DN+    SHV+PALIRR  +A Q+GD + T  G+G PLR+F+++ DL  
Sbjct: 173 SLMPTNLYGPGDNYHPTGSHVLPALIRRFHEAKQRGDASVTCWGTGTPLREFLHADDLGE 232

Query: 651 AVHLGSSGTTTVSN 692
           A        +T+S+
Sbjct: 233 ACVFALEHWSTLSD 246


>UniRef50_O84974 Cluster: O-antigen biosynthesis protein; n=5;
           Helicobacter|Rep: O-antigen biosynthesis protein -
           Helicobacter pylori (Campylobacter pylori)
          Length = 310

 Score =  114 bits (275), Expect = 2e-24
 Identities = 57/196 (29%), Positives = 101/196 (51%)
 Frame = +3

Query: 114 LRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVK 293
           L DK   +A   ++KPT +IH A  VGG+  NM     +  EN+ +   +  +     VK
Sbjct: 41  LLDKDNVQAYLKEYKPTGIIHCAGRVGGIVANMNDLSTYMVENLLMGLYLFSSALDLGVK 100

Query: 294 KVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTS 473
           K ++  S+C +P     P+ E+ + NG    +N GY+ AK  +       +   G  + +
Sbjct: 101 KAINLASSCAYPKYAPNPLKESDLLNGSLEPTNEGYALAKLSVMKYCEYVSTEKGGFYKT 160

Query: 474 VIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARA 653
           ++PCN++G +D F  + +H+IP LI RM  A  K +  F + G G   R+++ + DLAR 
Sbjct: 161 LVPCNLYGEFDKFEEKIAHMIPGLIARMHTAKLKNEKNFAMWGDGTARREYLNAKDLARF 220

Query: 654 VHLGSSGTTTVSNLLS 701
           + L      ++ ++++
Sbjct: 221 IALAYENIASMPSVMN 236


>UniRef50_A1B1K8 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           Alphaproteobacteria|Rep: NAD-dependent
           epimerase/dehydratase - Paracoccus denitrificans (strain
           Pd 1222)
          Length = 307

 Score =  112 bits (269), Expect = 9e-24
 Identities = 57/183 (31%), Positives = 96/183 (52%), Gaps = 1/183 (0%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           DL D        A+ +P  V+H A  VGG+  NMA  + +   N  I  N++ AC    +
Sbjct: 37  DLCDARALRDWLARQRPDAVVHAAGAVGGIQANMAEPVRYLAGNALIGLNLITACRDAGI 96

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRM-IDVLNRGYNESYGCMF 467
             +++  S+C++P      + E  +  G    SN GY+ AK M + +++    E     +
Sbjct: 97  PVLINLSSSCVYPRDLGRDLSEEQILTGALEPSNEGYALAKIMAMRLVDYTCREDRSLQW 156

Query: 468 TSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLA 647
            ++IPCN++GP+D F    SH++PA+I ++  A  +G  T  + G G   R+F+Y+ DLA
Sbjct: 157 RTLIPCNLYGPHDKFDPRRSHLLPAIIHKIHRARVEGHETVEIWGDGTARREFMYAGDLA 216

Query: 648 RAV 656
            A+
Sbjct: 217 DAI 219


>UniRef50_Q9AQ09 Cluster: Putative nodulation NAD-dependent
           nucleotide sugar epimerase; n=1; Bradyrhizobium sp.
           WM9|Rep: Putative nodulation NAD-dependent nucleotide
           sugar epimerase - Bradyrhizobium sp. (strain WM9)
          Length = 289

 Score =  110 bits (265), Expect = 3e-23
 Identities = 66/188 (35%), Positives = 100/188 (53%), Gaps = 1/188 (0%)
 Frame = +3

Query: 102 KDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHK 281
           ++ DL ++      FAK +P  +   AA VGG+  N     +F  +N++I  N++QA H+
Sbjct: 23  REVDLCNQAAVFDWFAKVRPQVIFLAAAKVGGIVANATLRAEFIYDNIAIAANVIQAAHQ 82

Query: 282 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 461
              +K++   S+CI+P     P+ E  V  GP            +M++     Y   YG 
Sbjct: 83  NGAEKLMFLGSSCIYPKLAAQPLREDSVLTGPLEI---------KMVEA----YRSQYGS 129

Query: 462 MFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLD 641
            F SV+P N++GP DN+  E SHV+ ALIRR  +A   G  +  V G+G P R+F+Y  D
Sbjct: 130 DFISVMPTNLYGPGDNYHPEYSHVVAALIRRFHEAKVSGARSVVVWGTGTPRREFLYVDD 189

Query: 642 LARA-VHL 662
           +A A VHL
Sbjct: 190 MADACVHL 197


>UniRef50_A2BXU6 Cluster: Putative fucose synthetase; n=1;
           Prochlorococcus marinus str. MIT 9515|Rep: Putative
           fucose synthetase - Prochlorococcus marinus (strain MIT
           9515)
          Length = 320

 Score =  108 bits (260), Expect = 1e-22
 Identities = 63/187 (33%), Positives = 95/187 (50%)
 Frame = +3

Query: 102 KDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHK 281
           KD DLR++         HKP  +I  AA VGG+  N     +F  +N+ I  NI+ A  K
Sbjct: 40  KDLDLRNQIDVNNFIGIHKPDKIILSAAKVGGIQANQNFKCEFLYDNLMIQTNIIDAAAK 99

Query: 282 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 461
            N K +V   S+CI+P ++  PI E  +  G    +N  Y+ AK +   L + Y E Y  
Sbjct: 100 NNTKTLVFIGSSCIYPRESEQPIKENYLLTGLLEPTNEPYALAKIVGLKLAKLYAEKYNI 159

Query: 462 MFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLD 641
                + CN++G  DNF L +SHV+ +L+R+  DA+        + GSG+  R+F+   D
Sbjct: 160 QCICPMFCNLYGNNDNFDLINSHVLSSLVRKFVDAVDNSIGKVELWGSGEVFREFLNVED 219

Query: 642 LARAVHL 662
              A+ L
Sbjct: 220 AVDAIIL 226


>UniRef50_Q8VQ41 Cluster: WbdJ; n=13; Bacteria|Rep: WbdJ -
           Escherichia coli
          Length = 307

 Score =  108 bits (259), Expect = 2e-22
 Identities = 58/188 (30%), Positives = 93/188 (49%), Gaps = 1/188 (0%)
 Frame = +3

Query: 99  SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACH 278
           S + +L D          H P  +IH A +VGG+  N+   +DF   N+ +  NI+    
Sbjct: 32  SSELNLLDNKAVHDYITCHSPDLIIHAAGLVGGIQANIKRPVDFLVSNLKMGVNIVNEAK 91

Query: 279 KYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYN-ESY 455
              VK  ++  S+C++P      I E  +  G    +N GY+ AK  +  L      ES 
Sbjct: 92  NCGVKNFINLGSSCMYPKGIDTAISEDALLTGKLEHTNEGYALAKITVAKLCEYITKESE 151

Query: 456 GCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYS 635
           G  + ++IPCN++G YD F   SSH+IPA+I R+ +A         + G G+  R+F+Y+
Sbjct: 152 GYHYKTIIPCNLYGKYDKFDEHSSHMIPAVINRIHNAKVNNIKLIEIWGDGESRREFMYA 211

Query: 636 LDLARAVH 659
            D A  ++
Sbjct: 212 EDFANFIY 219


>UniRef50_Q8L2G9 Cluster: Fcl; n=2; Enterobacteriaceae|Rep: Fcl -
           Erwinia chrysanthemi
          Length = 312

 Score =  108 bits (259), Expect = 2e-22
 Identities = 59/187 (31%), Positives = 96/187 (51%), Gaps = 1/187 (0%)
 Frame = +3

Query: 144 FAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCI 323
           F +H+P +V HLA++V GL  N+ + L     N  IN N++ ACHK+NVKK+    +   
Sbjct: 52  FNQHQPDYVFHLASLVFGLKGNLDNQLKSISNNTIINQNVILACHKFNVKKIFFAGTVAS 111

Query: 324 FP-DKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGP 500
           +P      P+DE  +  G PH   +GY+ +KR      +  N+ +   +   +  N+FG 
Sbjct: 112 YPFPYVQLPLDEGDLMLGEPHGGEYGYAMSKRHALAYLKILNQYHNVDYCYALFTNLFGA 171

Query: 501 YDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAVHLGSSGTT 680
            D F   + HVIP+LI +  +++ +GD   TV G  +  R F+Y+     A     +  +
Sbjct: 172 NDKFDPINGHVIPSLIDKTYNSLLRGDNQLTVWGRPETTRDFLYNKQAGLAALHVMNNLS 231

Query: 681 TVSNLLS 701
            V N+ S
Sbjct: 232 GVVNIAS 238


>UniRef50_Q9XDD7 Cluster: Bme10; n=1; Brucella melitensis|Rep: Bme10
           - Brucella melitensis
          Length = 246

 Score =  105 bits (253), Expect = 8e-22
 Identities = 54/156 (34%), Positives = 84/156 (53%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           DL  +  TE   + H+P  +I  AA VGG+  N     DF   N++I  N++ A H+  V
Sbjct: 53  DLTRQGPTENFISGHRPDVIIIAAARVGGILANSRFPADFLYNNLAIGMNLIHAAHQIGV 112

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 470
           ++++   S+CI+P     P+ E  +  GP   +N  Y+ AK       +     +G  F 
Sbjct: 113 ERLLWLGSSCIYPRDAAQPLTEDALLTGPLEPTNEAYAIAKIAGLKYAQSCARQFGDRFI 172

Query: 471 SVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKG 578
           + +P N++GP DNF   SSHV+PALIRR+ +A  +G
Sbjct: 173 TAMPTNLYGPNDNFDPTSSHVLPALIRRVHEARMRG 208


>UniRef50_Q7MV22 Cluster: GDP-fucose synthetase; n=5; Bacteria|Rep:
           GDP-fucose synthetase - Porphyromonas gingivalis
           (Bacteroides gingivalis)
          Length = 357

 Score =  104 bits (250), Expect = 2e-21
 Identities = 53/149 (35%), Positives = 79/149 (53%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           DL D       F K +P +V   AA VGG+  N     DF   N+ I  NI+   +++ V
Sbjct: 41  DLLDAVAVREFFDKEEPQYVFLAAAYVGGIVANNRFRADFIYRNLGIQQNIIGESYRHRV 100

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 470
            K++   STCI+P     P+ E  +   P   +N  Y+ AK     +   +N  YG  + 
Sbjct: 101 SKLMFLGSTCIYPRDARQPMREEELLTAPLEYTNEPYAIAKIAGLKMCESFNLQYGTNYI 160

Query: 471 SVIPCNVFGPYDNFSLESSHVIPALIRRM 557
           +V+P N++GP DNF LE SHV+PA+IR++
Sbjct: 161 AVMPTNLYGPNDNFDLERSHVLPAMIRKI 189


>UniRef50_Q2BI22 Cluster: DTDP-glucose dehydratase; n=1;
           Neptuniibacter caesariensis|Rep: DTDP-glucose
           dehydratase - Neptuniibacter caesariensis
          Length = 312

 Score =  103 bits (248), Expect = 3e-21
 Identities = 58/186 (31%), Positives = 96/186 (51%)
 Frame = +3

Query: 99  SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACH 278
           S + DL    Q E          + HLAA VGG+ +  AH  + F  N+ +N  +L A  
Sbjct: 37  SSECDLLCYEQIEVSLQSESFDLIFHLAADVGGIGYMQAHGAEVFENNLLMNTQLLHAAR 96

Query: 279 KYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 458
           +  V K+V+  S   +P +   P  E+ + +G P     GY+YAKR + V +    + +G
Sbjct: 97  RNGVGKLVNIASINCYPAEAEAPYLESSLFDGQPALPVLGYAYAKRAMLVHSELARQQFG 156

Query: 459 CMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSL 638
               ++I  +V+GP ++FSL+++ V+PA + R  DA   G    T  G+G+P+R F++  
Sbjct: 157 FNSINLILDSVYGPGESFSLDTARVLPANVARFVDAAHSGVEEVTCWGTGEPVRDFLHVD 216

Query: 639 DLARAV 656
           D   A+
Sbjct: 217 DAVSAI 222


>UniRef50_P33217 Cluster: Nodulation protein nolK; n=2;
           Alphaproteobacteria|Rep: Nodulation protein nolK -
           Azorhizobium caulinodans
          Length = 312

 Score =  103 bits (246), Expect = 6e-21
 Identities = 52/186 (27%), Positives = 99/186 (53%)
 Frame = +3

Query: 99  SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACH 278
           S D DLR+    E    +  P  V+H A +VGG+  N+A  + F  +N ++  N++ +  
Sbjct: 36  SVDLDLRNAEAVEQYIRRQLPDVVVHAAGVVGGIHANIADPIHFLADNAAMALNVVMSSF 95

Query: 279 KYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 458
           +  V  +++  S+C++P     P+ E  +  GP   +N GY+ AK +   +    ++   
Sbjct: 96  RSEVVTLINLSSSCMYPACIEGPLKECDILRGPFEVTNEGYALAKTVGLKICEYIDKLPN 155

Query: 459 CMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSL 638
             + ++I CN++G  DNF    SH++PA+I ++  A Q G  + ++ G G   R+F+++ 
Sbjct: 156 FNYKTLIACNLYGVGDNFDPRRSHLLPAIIEKIHKASQCGSESVSIWGDGTARREFMFAY 215

Query: 639 DLARAV 656
           D A+ +
Sbjct: 216 DFAKII 221


>UniRef50_Q67WR5 Cluster: Putative GDP-L-fucose synthase 2; n=4;
           Oryza sativa|Rep: Putative GDP-L-fucose synthase 2 -
           Oryza sativa subsp. japonica (Rice)
          Length = 347

 Score =  101 bits (243), Expect = 1e-20
 Identities = 63/183 (34%), Positives = 91/183 (49%), Gaps = 1/183 (0%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY-N 287
           DL  +   EA FA   P +VI  AA VGG+  + A   ++  EN+ I  N++ A  +  +
Sbjct: 71  DLACQAAVEAFFAAELPRYVILAAAKVGGVHASSAAPAEYLTENLRITVNVVDAARRCGS 130

Query: 288 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 467
           V+K++   S+ I+P     P  E+ +  GPP   +  Y+  K     + +     YG   
Sbjct: 131 VRKLLVLASSTIYPADAPQPTPESALLTGPPAEGSEWYAIPKIAGIKMCQAVRAEYGLDA 190

Query: 468 TSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLA 647
            +  P N++GP   F  E SHVIPALIRR   A  +G     V GSG   R+F +  DLA
Sbjct: 191 IAAAPNNLYGPRHPFPPEHSHVIPALIRRFHRAKLEGAGEVAVWGSGAAAREFTHVDDLA 250

Query: 648 RAV 656
            AV
Sbjct: 251 EAV 253


>UniRef50_A0R4U4 Cluster: NAD dependent epimerase/dehydratase family
           protein; n=1; Mycobacterium smegmatis str. MC2 155|Rep:
           NAD dependent epimerase/dehydratase family protein -
           Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
          Length = 323

 Score = 79.0 bits (186), Expect = 1e-13
 Identities = 57/190 (30%), Positives = 92/190 (48%), Gaps = 5/190 (2%)
 Frame = +3

Query: 102 KDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGL--FHNMAHNLDFFRENMSINDNILQAC 275
           + GDLR   +  A  A    THVIHLAA+VGG+  FH + H L     N  + +++  A 
Sbjct: 48  RTGDLRSADEARA--AVDGCTHVIHLAAIVGGIANFHRLPHTL--LEMNTGLYNSVFSAA 103

Query: 276 HKYNVKKVVSCLSTCIFPDKTTYP-IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNES 452
            +  V+++V   S+ +F   T +P  +E ++   PP S+   Y ++K   ++  R  +E 
Sbjct: 104 LREGVERLVYVSSSMVFEQATQFPTTEEHLLDCRPPRSA---YGFSKLTGEIYCRAVHEE 160

Query: 453 YGCMFTSVIPCNVFGPYDNFSLES--SHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQF 626
           +G  FT   P N +GP +    E   +H +P LIR+       G     + GSG   R  
Sbjct: 161 HGLPFTICRPFNAYGPGELPDTEPGIAHAVPDLIRK----ALSGQHPLQIFGSGTQTRTL 216

Query: 627 IYSLDLARAV 656
            +  D+A  +
Sbjct: 217 THVDDIADGI 226


>UniRef50_Q18EM2 Cluster: Nucleoside-diphosphate-sugar epimerase;
           n=1; Haloquadratum walsbyi DSM 16790|Rep:
           Nucleoside-diphosphate-sugar epimerase - Haloquadratum
           walsbyi (strain DSM 16790)
          Length = 345

 Score = 69.7 bits (163), Expect = 7e-11
 Identities = 50/167 (29%), Positives = 83/167 (49%), Gaps = 4/167 (2%)
 Frame = +3

Query: 168 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDK---- 335
           V HLAA VGG+ +    N+     ++ +N ++L+A    +V + +   S C++  +    
Sbjct: 85  VYHLAASVGGIHYIQRENVHGLTPSVLMNQHMLEAARIQDVDRFLFASSACVYRQQHDEL 144

Query: 336 TTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFS 515
             +  D+ +  N  PHS+   Y +AK + +V    Y+        +V   N +GP +N  
Sbjct: 145 NRFSEDQAIPAN--PHST---YGWAKVLGEVACDAYHTDTTVDTGAVRIFNAYGPRENLD 199

Query: 516 LESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAV 656
            +SSHVIPAL R++ +A   GD +  + G G   R FIY  DL   +
Sbjct: 200 PDSSHVIPALCRKVIEA-DDGD-SIELFGDGTQERGFIYITDLVEGM 244


>UniRef50_Q30CR4 Cluster: LipDig4; n=3; Streptomyces|Rep: LipDig4 -
           Streptomyces aureofaciens
          Length = 355

 Score = 67.7 bits (158), Expect = 3e-10
 Identities = 50/183 (27%), Positives = 78/183 (42%), Gaps = 2/183 (1%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTH--VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 284
           DL D T   A      P    ++H AA+ G       +       NM +  N+L+A    
Sbjct: 85  DLLDDTALSAALRSVTPRVDLIVHCAALYGNADFKKRNPALILDANMRMASNVLRAARAC 144

Query: 285 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
           +V  VV   S  I+ +    P  E   +   P  +  GY+ AK   ++L   +   YG  
Sbjct: 145 DVGDVVMMGSAEIYSELAPSPAREDDDYRRYPVPTQNGYALAKIYTEMLAEFFRTQYGMR 204

Query: 465 FTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDL 644
                P NV+GP D+F    S V+P+L+ R    + +G+    + G G   R F++  D+
Sbjct: 205 IFVPRPTNVYGPRDDFDASVSRVVPSLMNR----IARGE-DIEIWGDGSQTRTFVHVRDV 259

Query: 645 ARA 653
            RA
Sbjct: 260 VRA 262


>UniRef50_Q1J353 Cluster: GDP-L-fucose synthase; n=1; Deinococcus
           geothermalis DSM 11300|Rep: GDP-L-fucose synthase -
           Deinococcus geothermalis (strain DSM 11300)
          Length = 316

 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 43/185 (23%), Positives = 79/185 (42%)
 Frame = +3

Query: 99  SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACH 278
           +++ DLR+K Q  A F K  P +V   +  V G   +  +   +  +N+ +  N + A +
Sbjct: 39  ARELDLREKDQVHAFFEKELPDYVFVSSVKVEGPVRDAIYPAQWLHDNLLVMANTIHAAY 98

Query: 279 KYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 458
            Y+V+K+V    +  + D    P   + +       +    +   +    L   Y   YG
Sbjct: 99  LYDVEKLVCIDCSSTYADLGALPRTMSYLQAELIEETQRVCTVVSQTTTELCDSYRRQYG 158

Query: 459 CMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSL 638
           C F S +  +++GP    S + S V+ AL+  M  A + G          +  R  +Y+ 
Sbjct: 159 CDFVSAVFSSLYGPPLGGSGQRSSVVLALLHDMQRAKETGQAAVRWPSDDRWCRDLLYAD 218

Query: 639 DLARA 653
           D+A A
Sbjct: 219 DMADA 223


>UniRef50_A5GEL7 Cluster: NAD-dependent epimerase/dehydratase
           precursor; n=1; Geobacter uraniumreducens Rf4|Rep:
           NAD-dependent epimerase/dehydratase precursor -
           Geobacter uraniumreducens Rf4
          Length = 336

 Score = 63.7 bits (148), Expect = 4e-09
 Identities = 46/172 (26%), Positives = 84/172 (48%), Gaps = 6/172 (3%)
 Frame = +3

Query: 165 HVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFP----- 329
           +V HLA +VGG+    ++ L  FR+N++I+ N++ AC    +   +   + C +P     
Sbjct: 82  YVFHLADIVGGIQFAFSNELFIFRQNITIDTNVVSACITNGIGNYIYVGTACSYPKYLQM 141

Query: 330 DKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPC-NVFGPYD 506
           +K    + E  V+   P SS +G+S   +++           G +   ++   NV+GP  
Sbjct: 142 NKGITALKEDQVYPAEPESS-YGWS---KLMGEYGADLALKSGRINVGILRFHNVYGPGV 197

Query: 507 NFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAVHL 662
            F   ++ V+P+L+R+   A++     F V GSG   R F+Y  D+   + L
Sbjct: 198 EFEGNTAQVLPSLMRK---AIRFPQEDFIVWGSGNQYRDFVYIDDIVEGLIL 246


>UniRef50_A6GLY7 Cluster: Putative uncharacterized protein; n=1;
           Limnobacter sp. MED105|Rep: Putative uncharacterized
           protein - Limnobacter sp. MED105
          Length = 294

 Score = 63.3 bits (147), Expect = 6e-09
 Identities = 57/210 (27%), Positives = 92/210 (43%), Gaps = 2/210 (0%)
 Frame = +3

Query: 33  VIERDRQKRNSDYDSETWIFSGS--KDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFH 206
           VI  D        + E W+   +   +GD+RD++  E L A+       HLAA+V  +  
Sbjct: 12  VIVLDNLSSGRRENIENWLGPNTCLVEGDIRDQSLVENLLAE--TAGAFHLAALVS-VPQ 68

Query: 207 NMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHS 386
           ++    + F  N+    N+L+A  K   KK+V   S  ++ ++ +YP+ ETM   G P S
Sbjct: 69  SIERPTESFSINLEGTLNLLEASRKQGNKKIVFASSAAVYGNRHSYPVSETMA--GQPIS 126

Query: 387 SNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDA 566
               Y   K M +     +   Y      +   NV+GP  + S   S VI   I R+   
Sbjct: 127 P---YGLHKLMCEQHAELFANLYNVNSVGMRFFNVYGPRQDPSSPYSGVISIFIDRLRRG 183

Query: 567 MQKGDPTFTVMGSGKPLRQFIYSLDLARAV 656
           +       T+ G G   R F+Y  D+ +A+
Sbjct: 184 LAP-----TIYGDGSQTRDFVYVGDVVQAL 208


>UniRef50_Q55412 Cluster: Slr0583 protein; n=3; Chroococcales|Rep:
           Slr0583 protein - Synechocystis sp. (strain PCC 6803)
          Length = 310

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 47/180 (26%), Positives = 80/180 (44%), Gaps = 3/180 (1%)
 Frame = +3

Query: 120 DKTQTEAL--FAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVK 293
           D TQ ++L  F K     + HLAA        ++H  + +  N  +N N+L   H    +
Sbjct: 36  DLTQPDSLHQFTKGSFDQIYHLAAWTQAGDFCLSHPGEQWLINQKLNTNVLDWWHSQQPQ 95

Query: 294 -KVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 470
            K++   ++C +      P++E     G P  S F Y+  KRM+        + YG  + 
Sbjct: 96  AKLIFMGTSCAYDPNL--PLEEEYYLTGLPIDSLFTYAMTKRMLYAGALALQKQYGLKYL 153

Query: 471 SVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLAR 650
            ++P  ++GP  +      H I  LIR++      G+ T T+ G G   R+ ++  D AR
Sbjct: 154 CLVPSTLYGPGYHTDGRQMHFIFDLIRKIIRGKLYGE-TVTLWGDGYQRRELVFVEDFAR 212


>UniRef50_Q0W7F9 Cluster: Putative UDP-glucose 4-epimerase; n=1;
           uncultured methanogenic archaeon RC-I|Rep: Putative
           UDP-glucose 4-epimerase - Uncultured methanogenic
           archaeon RC-I
          Length = 306

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 52/183 (28%), Positives = 85/183 (46%)
 Frame = +3

Query: 168 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 347
           V HLAA +  +  ++ + +  F  N     N+L+   K  VKK V   S  ++      P
Sbjct: 70  VYHLAA-ISNVDASIRNPIRTFETNAMGTANVLEEARKAGVKKFVYVSSAHVYGVPQYLP 128

Query: 348 IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESS 527
           IDE   H   P  +   Y+ +K   + + + Y  SYG  +  + P N+FGP      + S
Sbjct: 129 IDEK--HPVVPREA---YAASKIAAENIVQAYGNSYGIEYAILRPFNIFGP----GQDPS 179

Query: 528 HVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAVHLGSSGTTTVSNLLSYQ 707
            +IP +I++   A++ G      +G+ +P R F+Y  D  R + L     T + N+ S Q
Sbjct: 180 FLIPGVIKQ---ALENG---VIKVGNTEPTRDFLYIEDAVRVMLLAGEKGTGIFNIGSGQ 233

Query: 708 LTK 716
            TK
Sbjct: 234 QTK 236


>UniRef50_Q83DA9 Cluster: NAD dependent epimerase/dehydratase family
           protein; n=9; Bacteria|Rep: NAD dependent
           epimerase/dehydratase family protein - Coxiella burnetii
          Length = 330

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 51/179 (28%), Positives = 79/179 (44%), Gaps = 1/179 (0%)
 Frame = +3

Query: 120 DKTQTEALFAKHKPTH-VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKK 296
           D  QT+ L    K    V H AA+   L     +    F+ N+    N+L+ C    VK+
Sbjct: 64  DINQTDILNTALKGVDGVFHFAAL--WLLQCYEYPRSAFQTNIQGTFNVLETCVAQGVKR 121

Query: 297 VVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSV 476
           +V   S  ++ D    P+ E   H   P +S   Y   K   + +   Y+  YG  F  +
Sbjct: 122 LVFSSSASVYGDALEEPMTEA--H---PFNSRTFYGATKIAGEAMATAYHHRYGLPFVGL 176

Query: 477 IPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARA 653
              NV+GP  ++    +++  A+I +M DA+ KG P  T+ G G     F+Y  D A A
Sbjct: 177 RYMNVYGPRQDY--RGAYI--AVIMKMLDALDKGQP-MTLYGDGSQAYDFVYVEDCAAA 230


>UniRef50_Q9K7I2 Cluster: UDP-glucose 4-epimerase; n=17; cellular
           organisms|Rep: UDP-glucose 4-epimerase - Bacillus
           halodurans
          Length = 308

 Score = 60.1 bits (139), Expect = 5e-08
 Identities = 54/199 (27%), Positives = 93/199 (46%), Gaps = 3/199 (1%)
 Frame = +3

Query: 126 TQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSI--NDNILQACHKYNVKKV 299
           ++ + +F+K KP +VIH AA V       + NL  +    +I    N+L  C +Y V KV
Sbjct: 58  SELKDIFSKEKPNYVIHHAAQVD---VTKSINLPTYDAETNIIGTINLLSCCCQYEVDKV 114

Query: 300 VSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVI 479
           +   S  ++ D      D ++  + P    +F Y  +K + ++  R +++ YG  +T   
Sbjct: 115 IYASSCAVYGDTG----DSSITEDFPIQPISF-YGISKSVPEMYIRQFHDLYGLKYTIFR 169

Query: 480 PCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAVH 659
             NV+GP      E   VI     +   A+++  P   + G+G+  R FIY  D+A+A  
Sbjct: 170 YANVYGPRQTSKGEGG-VISIFTTK---ALKREQP--IIYGNGEQTRDFIYVEDIAKANA 223

Query: 660 LG-SSGTTTVSNLLSYQLT 713
           L    G   + N+ + Q T
Sbjct: 224 LALDIGDNEIFNIGTNQKT 242


>UniRef50_A1SL10 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           Actinomycetales|Rep: NAD-dependent epimerase/dehydratase
           - Nocardioides sp. (strain BAA-499 / JS614)
          Length = 346

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 54/200 (27%), Positives = 89/200 (44%), Gaps = 16/200 (8%)
 Frame = +3

Query: 105 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGL--FHNMAHNLDFFRENM--SINDNILQA 272
           +GD+RD      L A     H++  AA++GG+  FH   ++L    E +  +  D  ++A
Sbjct: 59  EGDVRDLELMADLVADCD--HLVAGAALIGGISYFHTYPYDLLATNERIIAATCDTAIRA 116

Query: 273 CHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNES 452
                ++KV    S+ +F     +P  E      PP  S++G+   K  ++   R   + 
Sbjct: 117 MPAGRLRKVTYLSSSMVFESTDRWPSKEGDERVIPPPLSSYGFQ--KLAVEYFARAAWDQ 174

Query: 453 YGCMFTSVIPCNVFG------------PYDNFSLESSHVIPALIRRMDDAMQKGDPTFTV 596
           Y   +T V P N  G            P  N  L  SHV+P LI+++   ++  DP   V
Sbjct: 175 YRVPYTIVRPFNCVGVGEGRALGDVEIPSGNIKLAMSHVVPDLIQKV---LRGQDPVH-V 230

Query: 597 MGSGKPLRQFIYSLDLARAV 656
           +G G  +R + Y  DLA  +
Sbjct: 231 LGDGSQVRHYTYGADLAEGI 250


>UniRef50_Q9ZHQ3 Cluster: 4-ketoreductase; n=2; Actinomycetales|Rep:
           4-ketoreductase - Streptomyces fradiae
          Length = 336

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 46/184 (25%), Positives = 74/184 (40%), Gaps = 3/184 (1%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTH--VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 284
           DL D+  T   F +  P    VIH A + G   +   H+      N+    ++L      
Sbjct: 65  DLCDEAATRRAFQEWAPGADVVIHCAGLDGNAQYKRDHSASVLDANVRGTAHVLNTARDT 124

Query: 285 NVKKVVSCLSTCIFPDKTTYPI-DETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 461
               VV   ST ++      P  ++  +    PH+ N GY  +K   +++   +   +G 
Sbjct: 125 GAGAVVLLSSTEVYCAPRDSPAREDEEIRRYVPHAGN-GYVLSKIFCEIMAELHGAEFGS 183

Query: 462 MFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLD 641
               V P NV+GP D      + VIP+++ R          T  + G G+  R FI+  D
Sbjct: 184 RIFRVRPGNVYGPRDGNGGTRTRVIPSMVAR-----AAAGETIEIWGDGRQTRSFIHVED 238

Query: 642 LARA 653
           L  A
Sbjct: 239 LVNA 242


>UniRef50_Q9YCT1 Cluster: DTDP-glucose 4,6-dehydratase; n=2;
           Thermoprotei|Rep: DTDP-glucose 4,6-dehydratase -
           Aeropyrum pernix
          Length = 330

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 52/190 (27%), Positives = 87/190 (45%), Gaps = 1/190 (0%)
 Frame = +3

Query: 96  GSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQAC 275
           G   GD+ D+ Q   +  + +P  V++ AA    +  ++     F R N+     IL+A 
Sbjct: 51  GFMRGDIADEEQFGRVLTEFEPDVVVNFAAETH-VDRSINEPAPFMRTNIIGVFTILEAI 109

Query: 276 HKYNVKKVVSCLSTC-IFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNES 452
            K   + V+  +ST  ++ D      + T      P + +  YS +K   D+L + Y  +
Sbjct: 110 RKRIDQIVLLHVSTDEVYGDLWNTGKEAT---ESDPLNPSSPYSASKASGDLLIKAYGRT 166

Query: 453 YGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIY 632
           YG  +  V PCN +GPY +       +IP  I R    +  G P   + G G  +R ++Y
Sbjct: 167 YGLKYRIVRPCNNYGPYQHV----EKLIPRTIIR----ILHGKPP-VIYGDGSQIRDWLY 217

Query: 633 SLDLARAVHL 662
             D ARA+H+
Sbjct: 218 VEDTARAIHV 227


>UniRef50_Q2NIA3 Cluster: Putative UDP-glucose 4-epimerase; n=1;
           Methanosphaera stadtmanae DSM 3091|Rep: Putative
           UDP-glucose 4-epimerase - Methanosphaera stadtmanae
           (strain DSM 3091)
          Length = 315

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 41/163 (25%), Positives = 78/163 (47%)
 Frame = +3

Query: 165 HVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTY 344
           ++ H AA++  +F ++       + N+  + N+LQA ++ N+KKV+S  S  ++ +    
Sbjct: 74  YLFHEAALIS-VFESIEQPKATNKTNIDGSFNVLQAAYESNIKKVISASSAAVYGETEVL 132

Query: 345 PIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLES 524
           P  ET+     P      Y+ +K ++++ +  + ++Y      +   NVFGP        
Sbjct: 133 PNVETL-----PLQPLSPYAVSKALLELYSYTFTQTYHLPTACLRYFNVFGPRQKADSPY 187

Query: 525 SHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARA 653
           S VIP  I  +       + T  + G G+  R FIY  ++A+A
Sbjct: 188 SGVIPKFISAL-----LNNETPVIYGDGEQTRDFIYVKNIAKA 225


>UniRef50_Q2S4X2 Cluster: Sugar epimerase BlmG; n=2;
           Bacteroidetes|Rep: Sugar epimerase BlmG - Salinibacter
           ruber (strain DSM 13855)
          Length = 380

 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 48/203 (23%), Positives = 84/203 (41%), Gaps = 3/203 (1%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           DLR+K       A     HV +LAA +GG+   + +N      +++IN ++L A    ++
Sbjct: 98  DLREKENCYR--ALENADHVYNLAADMGGMGF-IENNKALCMLSVTINTHLLMAARDMDI 154

Query: 291 KKVVSCLSTCIFPDKT--TYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
            +     S C++  +   T  ++     +  P  +  GY + K   + + R + E +G  
Sbjct: 155 DRYFYSSSACVYNQELQDTADVEPLSEEDAYPALAEDGYGWEKLFSERMCRHFREDFGVT 214

Query: 465 FTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDL 644
                  NV+GP+  +         AL R+  +A   G     + G G   R F+Y  D 
Sbjct: 215 TRVARYHNVYGPFGTYDGGREKAPAALTRKAIEAKLSGSDDIVIWGDGTQTRSFMYIDDC 274

Query: 645 ARAVH-LGSSGTTTVSNLLSYQL 710
            +    +  S  T   NL S +L
Sbjct: 275 VKGTQKIMHSDITEPINLGSDEL 297


>UniRef50_Q832Q5 Cluster: NAD-dependent epimerase/dehydratase family
           protein; n=6; Lactobacillales|Rep: NAD-dependent
           epimerase/dehydratase family protein - Enterococcus
           faecalis (Streptococcus faecalis)
          Length = 324

 Score = 56.4 bits (130), Expect = 7e-07
 Identities = 45/189 (23%), Positives = 93/189 (49%), Gaps = 3/189 (1%)
 Frame = +3

Query: 105 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 284
           +G + D+   E +  +++  ++ HLAA +  +  ++A  ++  + N      +L+   KY
Sbjct: 54  EGSVTDQQLMEKVLQEYQFDYIFHLAA-IASVADSVARPVETHQVNFESVLQLLELIRKY 112

Query: 285 --NVKKVVSCLSTCIFPDKTTYPI-DETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESY 455
             ++K++V   S  ++ D+ T P  +E+++    P++ +    +A     VLN  Y   Y
Sbjct: 113 QKDLKRLVFASSAAVYGDEPTLPKQEESVIRPLTPYAVD---KFASEKY-VLN--YCHLY 166

Query: 456 GCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYS 635
               ++V   NV+GP  N +   S VI  ++      +   + TF + G GK  R F++ 
Sbjct: 167 DVPTSAVRFFNVYGPNQNPNSPYSGVISIVMDSYKRLLANQEVTFNIFGDGKQSRDFVFV 226

Query: 636 LDLARAVHL 662
            D+ +A++L
Sbjct: 227 EDVVQALNL 235


>UniRef50_Q5SKQ2 Cluster: UDP-glucose 4-epimerase; n=4; Thermus|Rep:
           UDP-glucose 4-epimerase - Thermus thermophilus (strain
           HB8 / ATCC 27634 / DSM 579)
          Length = 311

 Score = 56.4 bits (130), Expect = 7e-07
 Identities = 51/182 (28%), Positives = 79/182 (43%), Gaps = 1/182 (0%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           DLRDK   E  F + +PTHV H AA            LD F  N+    N+L+AC +Y V
Sbjct: 51  DLRDKEGVERAFREFRPTHVSHQAAQASVKVSVEDPVLD-FEVNLLGGLNLLEACRQYGV 109

Query: 291 KKVV-SCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 467
           +K+V +     I+ +    P  E      PP   +  Y+ +K   +     Y +SYG  +
Sbjct: 110 EKLVFASTGGAIYGE---VPEGERAEETWPPRPKS-PYAASKAAFEHYLSVYGQSYGLKW 165

Query: 468 TSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLA 647
            S+   NV+GP  +   E+  V+     R+   +          G    +R ++Y  D+A
Sbjct: 166 VSLRYGNVYGPRQDPHGEAG-VVAIFAERVLKGLPVTLYARKTPGDEGCVRDYVYVGDVA 224

Query: 648 RA 653
            A
Sbjct: 225 EA 226


>UniRef50_A6CLM3 Cluster: UDP-glucose 4-epimerase; n=1; Bacillus sp.
           SG-1|Rep: UDP-glucose 4-epimerase - Bacillus sp. SG-1
          Length = 306

 Score = 56.4 bits (130), Expect = 7e-07
 Identities = 52/181 (28%), Positives = 81/181 (44%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           ++ DK  +  +F K +P  VIH+AA V      M   +D    N+    N+L  C KY V
Sbjct: 50  NITDKNLSN-VFDKERPDAVIHMAAQVDVSRSVMEPIMDA-EVNILGTINVLNECVKYKV 107

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 470
           KKVV   ++ ++ +     I E    N      +F Y  +K   ++    + + +G  +T
Sbjct: 108 KKVVYSSTSAVYGENVASEISE----NEKIMPISF-YGISKYTPELYLEAFFKIHGLKYT 162

Query: 471 SVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLAR 650
            +   NV+G       E   VIP  I  +   M+   P   + G GK  R FIY+ D+A 
Sbjct: 163 ILRYSNVYGERQGIKGEGG-VIPIFIHEL---MEDRSP--VIFGDGKQTRDFIYAGDVAE 216

Query: 651 A 653
           A
Sbjct: 217 A 217


>UniRef50_Q1GN57 Cluster: NAD-dependent epimerase/dehydratase; n=24;
           Alphaproteobacteria|Rep: NAD-dependent
           epimerase/dehydratase - Silicibacter sp. (strain TM1040)
          Length = 333

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 47/183 (25%), Positives = 76/183 (41%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           G L D  +   L A HKP  VIHLAA   G+ H++    D+   N+     +L+A   + 
Sbjct: 61  GKLEDPGRLMGLLADHKPNAVIHLAAQ-AGVRHSIDAPRDYLEANLIGTFEVLEAARAHP 119

Query: 288 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 467
            + ++   ++  +   T  P DE   H    H  +F Y+  K+  + +   Y   YG   
Sbjct: 120 PEHIMIASTSSAYGANTNIPFDE---HQKADHQMSF-YAATKKAGETMAHSYAHLYGLPT 175

Query: 468 TSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLA 647
           T      V+GP+    +       AL  +   A++ G+    V   G+  R F Y  DL 
Sbjct: 176 TMFRFFTVYGPWGRPDM-------ALF-KFTKAIEAGE-AIDVYNHGRMSRDFTYIDDLV 226

Query: 648 RAV 656
             +
Sbjct: 227 AGI 229


>UniRef50_A5GIA6 Cluster: NAD dependent epimerase/dehydratase; n=19;
           Bacteria|Rep: NAD dependent epimerase/dehydratase -
           Synechococcus sp. (strain WH7803)
          Length = 343

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 44/174 (25%), Positives = 78/174 (44%)
 Frame = +3

Query: 135 EALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLS 314
           + LFA+ KP  V++LAA   G+ +++ +   + + N+    NIL+ C  + V+ +V   S
Sbjct: 77  QELFAREKPRVVVNLAAQ-AGVRYSLENPAAYIQSNLVGFGNILEGCRHHGVENLVYASS 135

Query: 315 TCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVF 494
           + ++      P  E    N P       Y+ +K+  +++   Y+  YG   T +    V+
Sbjct: 136 SSVYGGNRNLPFHEQQPVNHPVSL----YAASKKANELMAHTYSHLYGLPATGLRFFTVY 191

Query: 495 GPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAV 656
           GP+         + P L  +   A+  G+P   V   GK  R F Y  D+   V
Sbjct: 192 GPWGR-----PDMAPMLFAK---AILAGEP-IKVFNHGKMQRDFTYIDDIVEGV 236


>UniRef50_A0L5P6 Cluster: UDP-glucose 4-epimerase; n=4;
           Bacteria|Rep: UDP-glucose 4-epimerase - Magnetococcus
           sp. (strain MC-1)
          Length = 337

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 56/194 (28%), Positives = 89/194 (45%), Gaps = 9/194 (4%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLA--AMVGGLFHNMAHNLDFFRENMSINDNILQACHK 281
           G L D  +   LFA+++P  VIHLA  A VG    +M     ++R N+     +L+   +
Sbjct: 50  GGLDDGAKLAGLFAQYQPQAVIHLAGRAYVG---ESMTDPALYYRNNVQAALVLLECMRQ 106

Query: 282 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 461
           Y  K ++   S   + +    PI E M      H  N  Y  +K M + + + Y + YG 
Sbjct: 107 YGCKNIIFSSSCATYGEHRQMPITEAM----SQHPIN-PYGRSKLMFEWMLQDY-QVYGL 160

Query: 462 MFTSVIPCNVFGPYDNFSLESSH-VIPALIRRMDDAMQKGDPTFTVMGS------GKPLR 620
              ++   N  G      +   H   P +I R+ +A +KG P FT+ G+      G  +R
Sbjct: 161 QSVALRYFNASGADLEGEIGEQHQPEPHIIPRLLEAARKGSP-FTIYGTDYESEDGTCVR 219

Query: 621 QFIYSLDLARAVHL 662
            +I+  DLA+A HL
Sbjct: 220 DYIHVSDLAQA-HL 232


>UniRef50_Q18EM3 Cluster: Nucleoside-diphosphate-sugar epimerase;
           n=1; Haloquadratum walsbyi DSM 16790|Rep:
           Nucleoside-diphosphate-sugar epimerase - Haloquadratum
           walsbyi (strain DSM 16790)
          Length = 339

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 49/177 (27%), Positives = 82/177 (46%), Gaps = 6/177 (3%)
 Frame = +3

Query: 168 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFP---DKT 338
           V HLAA  GG  +   +  +    NM++++ + +A  +  V+++    S C +P    + 
Sbjct: 77  VFHLAADHGGRGYISNYPANC-ATNMALDNIVYEAAAENGVERICFASSACTYPTDIQQE 135

Query: 339 TYPIDETMV---HNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDN 509
              + E MV     G  ++    Y +AK M +   + YNE Y    ++V     +GP +N
Sbjct: 136 RQRLHEEMVSFDERGGAYADEV-YGWAKLMGERSLQAYNEQYDIDTSAVRIFTAYGPREN 194

Query: 510 FSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAVHLGSSGTT 680
                +H   A+I  M  AM + DP F + G G+  R F Y  D+ RA+ L +   T
Sbjct: 195 ----ETH---AIIAFMAKAMARQDP-FQIWGDGEQTRNFTYVKDITRALRLAAEHIT 243


>UniRef50_Q8TXF0 Cluster: Nucleoside-diphosphate-sugar epimerase;
           n=1; Methanopyrus kandleri|Rep:
           Nucleoside-diphosphate-sugar epimerase - Methanopyrus
           kandleri
          Length = 309

 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 52/181 (28%), Positives = 85/181 (46%), Gaps = 1/181 (0%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           D+ D    E  F +++P  VIHLAA V  + ++M       R N     N++    +++V
Sbjct: 53  DVTDPRAVERTFREYRPEAVIHLAAQV-NVRYSMESPFVDARINALGTLNLVSLAAEHDV 111

Query: 291 KKVVSCLS-TCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 467
           ++ V   S   ++ +    P+DE   H   P  SN+G S  K   +   R Y E  G  +
Sbjct: 112 ERFVYASSGGAVYGEPEYLPVDEE--HPTRP-ISNYGVS--KLAGEYYVRVYAERDGFEY 166

Query: 468 TSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLA 647
             +   NV+GP  +   E+  VIP  + R      +G+P  T+ G G+  R F++  D+A
Sbjct: 167 VILRYANVYGPRQDPRGEAG-VIPIFLLR----AARGEP-LTIFGDGEQTRDFVFVEDVA 220

Query: 648 R 650
           R
Sbjct: 221 R 221


>UniRef50_A7HI28 Cluster: NAD-dependent epimerase/dehydratase; n=9;
           Bacteria|Rep: NAD-dependent epimerase/dehydratase -
           Anaeromyxobacter sp. Fw109-5
          Length = 373

 Score = 53.2 bits (122), Expect = 6e-06
 Identities = 46/183 (25%), Positives = 81/183 (44%), Gaps = 1/183 (0%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRE-NMSINDNILQACHKYN 287
           D+ D+   +A+  + +P +V+HLAA VG    N   N   + E N+    N+L  C +  
Sbjct: 103 DVADREALDAVLDEAEPEYVVHLAAQVG--VRNSVRNPRAYAETNLDGFFNVLDGCARRG 160

Query: 288 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 467
           V+ +V   S+ ++      P  E    +   H  +F Y+  K+  +++   Y+       
Sbjct: 161 VRHLVYASSSSVYGSNEKVPFSE---EDPVDHPISF-YAATKKANEIMAHAYSHLNRLPT 216

Query: 468 TSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLA 647
           T +    V+GP+         + P L  R   A+ +G+P  T+   G+ LR F Y  D+ 
Sbjct: 217 TGLRFFTVYGPWGR-----PDMAPILFGR---AILRGEP-ITLFNHGRMLRDFTYVDDVV 267

Query: 648 RAV 656
             V
Sbjct: 268 EVV 270


>UniRef50_A2SRX5 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Methanocorpusculum labreanum Z|Rep: NAD-dependent
           epimerase/dehydratase - Methanocorpusculum labreanum
           (strain ATCC 43576 / DSM 4855 / Z)
          Length = 307

 Score = 53.2 bits (122), Expect = 6e-06
 Identities = 48/191 (25%), Positives = 81/191 (42%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           G + D+     +   H    + HLAA V  +  ++   L     N +   NIL A  ++ 
Sbjct: 50  GSVTDRPLLAEICKTHSFEGIFHLAA-VASVQKSIEDPLLVHEVNATGTLNILNAAKEHG 108

Query: 288 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 467
           ++KVV   S   + D   +P  E M+    P S    Y+ +K   ++  R + + +G   
Sbjct: 109 IRKVVLSASAAAYGDNPVFPKREDMLPE--PLSP---YAVSKITAEMYCRNFADLFGVET 163

Query: 468 TSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLA 647
           T++   NVFGP  + + E + VIP    R+       D    + G G   R F++  D+ 
Sbjct: 164 TALRYFNVFGPRQDPNAEYAAVIPKFTERI-----VHDKKPVIFGDGNQTRDFVFVKDVV 218

Query: 648 RAVHLGSSGTT 680
            A  L  +  T
Sbjct: 219 LANMLAMNSHT 229


>UniRef50_Q8R8R8 Cluster: UDP-glucose 4-epimerase; n=15;
           Bacteria|Rep: UDP-glucose 4-epimerase -
           Thermoanaerobacter tengcongensis
          Length = 329

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 47/193 (24%), Positives = 92/193 (47%), Gaps = 11/193 (5%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAA--MVGGLFHNMAHNLDFFRENMSINDNILQACHK 281
           GDLRD+   + +F+++    V+H AA  +VG    ++ +   ++  N+    ++L+A  K
Sbjct: 49  GDLRDEDFLDKVFSENDIEAVMHFAASSLVG---ESVENPFKYYENNVCGTLSLLKAMKK 105

Query: 282 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 461
           + VKK+V   +  ++ +    PI+E          +N  Y   K  I+ + +  + +YG 
Sbjct: 106 HGVKKIVFSSTAAVYGEPERIPIEE----EDRTEPTN-PYGETKLAIEKMLKWADAAYGI 160

Query: 462 MFTSVIPCNVFGPYDNFSL-----ESSHVIPALIR----RMDDAMQKGDPTFTVMGSGKP 614
            + ++   NV G  +   +       +H+IP +++    + D  M  GD   T    G P
Sbjct: 161 KYVALRYFNVAGALETGEIGEDHSPETHLIPIILQVALGKRDKVMIYGDDYPT--KDGTP 218

Query: 615 LRQFIYSLDLARA 653
           +R +I+ +DL  A
Sbjct: 219 IRDYIHVMDLVDA 231


>UniRef50_Q83W21 Cluster: Ata17 protein; n=9; Bacteria|Rep: Ata17
           protein - Streptomyces capreolus
          Length = 384

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 41/166 (24%), Positives = 65/166 (39%), Gaps = 2/166 (1%)
 Frame = +3

Query: 168 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFP--DKTT 341
           V  LAA +GG+    A++    + N  I+ N L+A  K  V +     S C++P   +  
Sbjct: 115 VYSLAADMGGMGFISANHATIMKNNSLIDLNTLEAARKARVNRFFYASSACVYPAYRQNI 174

Query: 342 YPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLE 521
             +      +  P +   GY + K   + L   Y E YG         NV+GPY  +   
Sbjct: 175 TEVVGLREEDAYPAAPEDGYGWEKLNTEHLCSYYREEYGLPVRVARLHNVYGPYCTYDGG 234

Query: 522 SSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAVH 659
                 AL R+   A+ +      + G G   R + Y  D    +H
Sbjct: 235 REKSPAALARKA--ALAEPGGRMEIWGDGMQTRSYCYVDDCVEGIH 278


>UniRef50_A5UK04 Cluster: UDP-glucose 4-epimerase; n=2;
           Euryarchaeota|Rep: UDP-glucose 4-epimerase -
           Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM
           861)
          Length = 309

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 43/163 (26%), Positives = 77/163 (47%)
 Frame = +3

Query: 165 HVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTY 344
           ++ HLAAM      ++   +     N++    +L A    NVKKV+   S+ ++ +    
Sbjct: 72  YIFHLAAMASVPL-SVNDPIKCNDNNVNSTIKLLTAAKNQNVKKVIFSSSSAVYGNNANM 130

Query: 345 PIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLES 524
           P+ E+ +    P S    Y+ +K   ++  + + ESYG    ++   NVFGP  + + + 
Sbjct: 131 PLKESELMM--PTSP---YAASKANCELYLQAFEESYGLKSIALRYFNVFGPKQDKNSQY 185

Query: 525 SHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARA 653
           + VIP  I   D  +    P   + G G+  R FI+  D+A+A
Sbjct: 186 AAVIPNFI---DAILNNEHP--IIYGDGQQTRDFIFVKDVAKA 223


>UniRef50_Q9RWF7 Cluster: UDP-glucose 4-epimerase, putative; n=63;
           cellular organisms|Rep: UDP-glucose 4-epimerase,
           putative - Deinococcus radiodurans
          Length = 344

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 50/199 (25%), Positives = 83/199 (41%), Gaps = 1/199 (0%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           GD+RD     AL    +   V HLAA++   +  +A    +   N++   N+L+A     
Sbjct: 74  GDVRDAGSVRALMRDVQT--VYHLAALIAIPYSYVAPR-SYVETNITGTLNVLEAARDLG 130

Query: 288 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 467
             +V+   ++ ++    + PI     H   P      YS  K   D L   Y  S+G   
Sbjct: 131 TGRVIHTSTSEVYGTARSVPI-----HESHPLQGQSPYSATKIGADKLAESYFLSFGLPV 185

Query: 468 TSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLA 647
            ++ P N +GP  +    +  VIP +I ++         T   +G  +P R F Y  D A
Sbjct: 186 VTLRPFNTYGPRQS----ARAVIPTIISQL-----AAGRTEIKLGDLRPTRDFNYVADTA 236

Query: 648 RAVH-LGSSGTTTVSNLLS 701
           RA   +G +G   +   L+
Sbjct: 237 RAFRAVGEAGPEVLGRTLN 255


>UniRef50_Q9WYX9 Cluster: UDP-glucose 4-epimerase, putative; n=5;
           Thermotogaceae|Rep: UDP-glucose 4-epimerase, putative -
           Thermotoga maritima
          Length = 309

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 49/197 (24%), Positives = 86/197 (43%), Gaps = 3/197 (1%)
 Frame = +3

Query: 114 LRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVK 293
           + D+   E +F+ H+P +V HLAA             D  + N+  +  +L+   KY VK
Sbjct: 52  IEDEEMMERIFSLHRPEYVFHLAAQASVAISVREPARD-AKTNIIGSLVLLEKSIKYGVK 110

Query: 294 K-VVSCLSTCIFPDKT-TYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 467
           K + S     I+ +    +P  ET +    PH  +  Y  AK   ++    +   YG  +
Sbjct: 111 KFIFSSTGGAIYGENVKVFPTPETEI----PHPIS-PYGIAKYSTEMYLEFFAREYGLKY 165

Query: 468 TSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLA 647
           T +   NV+GP  +   E+      ++    + M +G+    + G G+ +R ++Y  D+ 
Sbjct: 166 TVLRYANVYGPRQDPYGEA-----GVVAIFTERMLRGEEVH-IFGDGEYVRDYVYVDDVV 219

Query: 648 RAVHLG-SSGTTTVSNL 695
           RA  L    G   V N+
Sbjct: 220 RANLLAMEKGDNEVFNI 236


>UniRef50_A5WE41 Cluster: NAD-dependent epimerase/dehydratase; n=5;
           Bacteria|Rep: NAD-dependent epimerase/dehydratase -
           Psychrobacter sp. PRwf-1
          Length = 357

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 46/182 (25%), Positives = 80/182 (43%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           D+ D+   E+LFA+H+   V HLAA   G+ +++ +   +   N+    NIL+ C ++NV
Sbjct: 79  DIADRAAMESLFAEHQFDAVCHLAAQ-AGVRYSIENPHVYVETNVVGFLNILEGCRQHNV 137

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 470
             +    S+ ++    + P  +T  H   P S    Y+  K+  +++   Y   +G   T
Sbjct: 138 DNLCFASSSSVYGLNQSQPF-KTSDHTDHPVSL---YAATKKSNEMMAHTYAHLFGIRCT 193

Query: 471 SVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLAR 650
            +    V+GP+         + P L     DA+    P   V   G   R F Y  D+A 
Sbjct: 194 GLRFFTVYGPWGR-----PDMAPMLFA---DAISNNRP-IKVFNHGDMSRDFTYVGDIAE 244

Query: 651 AV 656
            +
Sbjct: 245 GI 246


>UniRef50_Q70PA0 Cluster: Putative uncharacterized protein; n=1;
           Melittangium lichenicola|Rep: Putative uncharacterized
           protein - Melittangium lichenicola
          Length = 320

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 44/182 (24%), Positives = 80/182 (43%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           D+RD      LF   +P  V+HLAA VG    + + + ++   N++    +L+ C +  V
Sbjct: 61  DIRDAKACRELFDGARPERVVHLAARVGVRTLD-SESPEYAETNVTGFLQVLELCRRSRV 119

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 470
           + +V   S+ ++   +  P  E    + P       Y+  KR  +++   Y+  Y    T
Sbjct: 120 EHLVFASSSSVYGAGSDMPFSEDSAADRPLSL----YAATKRANEMMAHAYSHQYAMPIT 175

Query: 471 SVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLAR 650
            +   +V+GP+         + P +  R   AM +G  +  + G GK  R F Y  D+  
Sbjct: 176 GLRLFSVYGPWGR-----PDMAPMMFLR---AMLEG-RSLELHGEGKAQRDFTYIDDVVE 226

Query: 651 AV 656
           A+
Sbjct: 227 AL 228


>UniRef50_A7GZ40 Cluster: dTDP-glucose 4,6-dehydratase; n=1;
           Campylobacter curvus 525.92|Rep: dTDP-glucose
           4,6-dehydratase - Campylobacter curvus 525.92
          Length = 345

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 55/194 (28%), Positives = 91/194 (46%), Gaps = 10/194 (5%)
 Frame = +3

Query: 105 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRE-NMSINDNILQACHK 281
           +GD+ D+   E++F K+    VIH AA       N  +    F E N+    N+L     
Sbjct: 62  EGDICDRLLLESIFDKYSIKEVIHFAAETH--VDNSINKPGIFIETNVLGTFNVLDVAKS 119

Query: 282 YNVK---KVVSCLSTCIFPDKTTYPIDETMVHNG-----PPHSSNFGYSYAKRMIDVLNR 437
           + ++   +      TC F   +T  +  T+  +G       ++ N  YS +K   D++ R
Sbjct: 120 FWMEGPFRYKPQYETCKFYHISTDEVYGTLGDSGYFTEKSNYAPNSPYSASKASSDMIVR 179

Query: 438 GYNESYGCMFTSVIPC-NVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKP 614
            YN +YG M T +  C N +GP  N  +E    IP +I+   +A+ K  P   + G GK 
Sbjct: 180 SYNRTYG-MNTLITNCSNNYGP--NQHIEK--FIPTIIK---NAI-KNKP-IPIYGDGKN 229

Query: 615 LRQFIYSLDLARAV 656
           +R ++Y LD  +A+
Sbjct: 230 IRDWLYVLDHCKAI 243


>UniRef50_A6PV21 Cluster: UDP-glucose 4-epimerase; n=1; Victivallis
           vadensis ATCC BAA-548|Rep: UDP-glucose 4-epimerase -
           Victivallis vadensis ATCC BAA-548
          Length = 307

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 51/197 (25%), Positives = 90/197 (45%), Gaps = 9/197 (4%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAA--MVGGLFHNMAHNLDFFRENMSINDNILQACHK 281
           G+L D+ + +++  + K   ++H AA  +VG    +M     +FR N++   N+  A  +
Sbjct: 34  GNLSDREKIKSVCREGKFDAIMHFAAFSLVG---ESMKDPSKYFRNNIANGINLADAAVE 90

Query: 282 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 461
             VK  V   +   F    + PI E       P +    Y  +K   + + + Y+E YG 
Sbjct: 91  SGVKMFVFSSTAATFGQPESIPIKE--FDRQIPINP---YGESKLCFEKILKWYHEIYGI 145

Query: 462 MFTSVIPCNVFGPYDNFSLE---SSHVIPALIR----RMDDAMQKGDPTFTVMGSGKPLR 620
            + ++   N  G  +NF  +    +H+IP +++    + D  M  GD   T    G  +R
Sbjct: 146 NYAALRYFNAAGATENFGEDHRPETHLIPLILQTVRGKRDKLMLYGDDYDT--ADGTCVR 203

Query: 621 QFIYSLDLARAVHLGSS 671
            +I+ LDLA+A  L  S
Sbjct: 204 DYIHILDLAQAHELALS 220


>UniRef50_Q12UG3 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           Euryarchaeota|Rep: NAD-dependent epimerase/dehydratase -
           Methanococcoides burtonii (strain DSM 6242)
          Length = 299

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 45/173 (26%), Positives = 73/173 (42%)
 Frame = +3

Query: 168 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 347
           +IH AA +  +  +M       + N+    N+L+     N+++ V   S   + +    P
Sbjct: 66  IIHTAAQIS-VVRSMNEPFFDAQNNIMGTLNLLEEARHANIERFVYFSSAATYGNPLKVP 124

Query: 348 IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESS 527
           I ET  H   P S       A     ++   YN++YG   T + P N++ P  + S   S
Sbjct: 125 IGET--HPQEPLSPYGASKLAGEKYCIM---YNKAYGLPTTCIRPFNIYSPRQDPSNPYS 179

Query: 528 HVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAVHLGSSGTTTV 686
            VI   I ++      G  + T+ G G+  R FIY  D+   V L  S  T +
Sbjct: 180 GVISKFIDKV-----SGGASPTIFGDGEQTRDFIYVRDIVDLVDLMISKRTAI 227


>UniRef50_A3ERU6 Cluster: Nucleoside-diphosphate-sugar epimerase;
           n=2; Bacteria|Rep: Nucleoside-diphosphate-sugar
           epimerase - Leptospirillum sp. Group II UBA
          Length = 316

 Score = 50.0 bits (114), Expect = 6e-05
 Identities = 48/182 (26%), Positives = 89/182 (48%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           GD+R     E   A    T V H AA VG +  ++A   D    N++   N+L    ++ 
Sbjct: 53  GDVRSFADIEK--ALEGVTFVFHQAA-VGSVPRSIADPFDTQTANVNGTLNLLWKAKEFG 109

Query: 288 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 467
           V++VV   S+ ++ D    P  ET++ +  P S    Y+ +K   ++  + +++++G   
Sbjct: 110 VQRVVIAGSSSVYGDTPGMPRVETLLPS--PLSP---YALSKLSQELFGKIFSKTFGLDT 164

Query: 468 TSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLA 647
            ++   N+FGP  +   E + VIP  +R    A+ K D   T+ G+G+  R F +  ++ 
Sbjct: 165 VTLRYFNIFGPRQDPRSEYAAVIPRFVR----AILKKD-AVTINGTGEQSRDFTFIDNVV 219

Query: 648 RA 653
           +A
Sbjct: 220 QA 221


>UniRef50_A0B5G2 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           Methanomicrobia|Rep: NAD-dependent epimerase/dehydratase
           - Methanosaeta thermophila (strain DSM 6194 / PT)
           (Methanothrixthermophila (strain DSM 6194 / PT))
          Length = 310

 Score = 50.0 bits (114), Expect = 6e-05
 Identities = 47/163 (28%), Positives = 76/163 (46%)
 Frame = +3

Query: 165 HVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTY 344
           +V+H AA+   +  ++   +   R N+    ++L A     VK+VV   S+ ++ D    
Sbjct: 72  YVLHQAALPS-VQRSIMDPMATNRSNIDGTLSVLVAAMDCGVKRVVFASSSAVYGDSPEL 130

Query: 345 PIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLES 524
           P  E+++    P S    Y+  K + +   R + E YG    S+   NVFGP  + + E 
Sbjct: 131 PKRESLIPR--PMSP---YAVTKLVGEHYCRVFYEIYGIECVSLRYFNVFGPGQDPASEY 185

Query: 525 SHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARA 653
           + VIP  I    DA+  G     V G G+  R F+Y  D+ RA
Sbjct: 186 AAVIPKFI----DAVLSGSQP-VVYGDGEQTRDFVYVDDVVRA 223


>UniRef50_Q8DJM2 Cluster: Nucleotide sugar epimerase; n=61; cellular
           organisms|Rep: Nucleotide sugar epimerase -
           Synechococcus elongatus (Thermosynechococcus elongatus)
          Length = 338

 Score = 49.6 bits (113), Expect = 8e-05
 Identities = 45/182 (24%), Positives = 78/182 (42%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           DL D+     LFA   P  VIHLAA   G+ +++ +   +   N+    +IL+AC  + V
Sbjct: 64  DLVDRLGVNQLFADFSPQKVIHLAAQ-AGVRYSLENPFAYIDSNIVGFLHILEACRHHRV 122

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 470
           + +V   S+ ++      P     VH+   H  +  Y+  K+  +++   Y+  Y    T
Sbjct: 123 EHLVYASSSSVYGANKKLPFS---VHDNVDHPLSL-YAATKKANELMAHTYSHLYNIPTT 178

Query: 471 SVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLAR 650
            +    V+GP+    +       AL  +   A+   +P   V   GK  R F Y  D+  
Sbjct: 179 GLRFFTVYGPWGRPDM-------ALF-KFTRAILNNEP-LPVFNYGKHRRDFTYIDDIVE 229

Query: 651 AV 656
            +
Sbjct: 230 GI 231


>UniRef50_P72903 Cluster: UDP-glucose-4-epimerase; n=20;
           Bacteria|Rep: UDP-glucose-4-epimerase - Synechocystis
           sp. (strain PCC 6803)
          Length = 340

 Score = 49.6 bits (113), Expect = 8e-05
 Identities = 44/192 (22%), Positives = 89/192 (46%), Gaps = 7/192 (3%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           GDL D  +   +F +H+   V+H A  +  +  ++ H L+++  N S   ++++ C  + 
Sbjct: 55  GDLADTERLHQVFHEHEILAVMHFAGSL-IVPESLIHPLNYYANNTSNTLSLIRCCQIFG 113

Query: 288 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 467
           V +++   +  ++ + ++ PI E  +    P   N  Y  +K   + + + Y +S    +
Sbjct: 114 VNRLIFSSTAAVYGNSSSNPISEAEI----PCPIN-PYGRSKLASEWIIQDYAKSSALQY 168

Query: 468 TSVIPCNVFGPYDNFSL-ESSHVIPALIRRMDDAMQKGDPTFTVMGS------GKPLRQF 626
             +   NV G      L + S     L+R + DA+    P+  + G+      G  +R +
Sbjct: 169 VILRYFNVAGADPEGRLGQMSKTTTHLVRSVCDAILNLKPSLDIFGTDFPTRDGTAVRDY 228

Query: 627 IYSLDLARAVHL 662
           I+  DLA+A HL
Sbjct: 229 IHVEDLAKA-HL 239


>UniRef50_Q9KDV3 Cluster: UDP-glucose 4-epimerase; n=124; cellular
           organisms|Rep: UDP-glucose 4-epimerase - Bacillus
           halodurans
          Length = 334

 Score = 49.6 bits (113), Expect = 8e-05
 Identities = 49/196 (25%), Positives = 88/196 (44%), Gaps = 11/196 (5%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAA--MVGGLFHNMAHNLDFFRENMSINDNILQACHK 281
           GD+RD    + +F  H    VIH AA  +VG    ++   ++++  N+     +L+   +
Sbjct: 49  GDIRDDQLLDTIFTTHSIDTVIHFAANSLVG---ESVKQPIEYYENNVIGTHTLLKKMLE 105

Query: 282 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 461
           ++VKK+V   +   + +    PI E    + P   +N  Y   K  I+ +     E+YG 
Sbjct: 106 HDVKKIVFSSTAATYGEPVQIPIQE----SDPTIPTN-PYGETKLAIEKMFHWCQEAYGL 160

Query: 462 MFTSVIPCNVFGPYDNFSL-----ESSHVIPALIR----RMDDAMQKGDPTFTVMGSGKP 614
            +  +   N  G   N  +       SH+IP +++    + +     GD   T  GS   
Sbjct: 161 QYVCLRYFNAAGADPNGRIGEDHSPESHLIPIVLQVALGQRERVAIFGDDYQTEDGS--C 218

Query: 615 LRQFIYSLDLARAVHL 662
           +R +I+ +DLA A +L
Sbjct: 219 IRDYIHVMDLANAHYL 234


>UniRef50_Q5KWG9 Cluster: Nucleotide sugar epimerase; n=1;
           Geobacillus kaustophilus|Rep: Nucleotide sugar epimerase
           - Geobacillus kaustophilus
          Length = 314

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 37/131 (28%), Positives = 62/131 (47%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           DL D   T+  F++ +P  V HLAA+ G + +++AH L +   ++    N+L A  +  V
Sbjct: 60  DLLDGEATKRWFSQFRPDVVYHLAALPG-VPYSLAHPLAYIDYDIKATVNVLAAAGEAGV 118

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 470
             V+   S+ ++ D+   P+ E M  +G   S    Y+ AK   +     Y   YG   T
Sbjct: 119 AHVLFASSSSVYGDRGNVPLREEMA-DGRVVSP---YAAAKYGAESFCHAYAHLYGYQMT 174

Query: 471 SVIPCNVFGPY 503
                 V+GP+
Sbjct: 175 IFRYFTVYGPW 185


>UniRef50_Q5KUQ5 Cluster: UDP-glucose 4-epimerase; n=5;
           Bacteria|Rep: UDP-glucose 4-epimerase - Geobacillus
           kaustophilus
          Length = 323

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 45/191 (23%), Positives = 88/191 (46%), Gaps = 9/191 (4%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAA--MVGGLFHNMAHNLDFFRENMSINDNILQACHK 281
           GDL +K   E +F K+    V+H AA  +VG    ++ + L +++ N++    +L+   K
Sbjct: 48  GDLGNKADLEPIFGKYPIQAVMHFAANSLVG---ESVVNPLKYYQNNVAATLTLLETMLK 104

Query: 282 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 461
           YNVK  +   +   +      P  E +  + P +  N  Y  +K MI+ +   +  +YG 
Sbjct: 105 YNVKNFIFSSTAATY----GIPNVELITEDCPTNPIN-PYGRSKLMIEQILADFASAYGL 159

Query: 462 MFTSVIPCNVFGPYDNFSL-----ESSHVIPALIRRMDDAMQKGDPTFTVMGS--GKPLR 620
            +  +   N  G +++  +       +H+IP +++ +     K     T   +  G  +R
Sbjct: 160 NYVVLRYFNAAGAHESGEIGEDHNPETHLIPLVLQHLLGQRDKISVFGTDYDTPDGTCIR 219

Query: 621 QFIYSLDLARA 653
            +I+  DLA+A
Sbjct: 220 DYIHVTDLAKA 230


>UniRef50_Q9FB21 Cluster: Sugar epimerase BlmG; n=1; Streptomyces
           verticillus|Rep: Sugar epimerase BlmG - Streptomyces
           verticillus
          Length = 325

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 41/177 (23%), Positives = 69/177 (38%), Gaps = 3/177 (1%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           DLRD  Q     A      V  LAA +GG+        +   +N+ I+ + ++AC    V
Sbjct: 50  DLRDAAQAARAVAG--ADSVFALAANMGGIGWTHTAPAEILHDNLLISTHTIEACRAAGV 107

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNGP--PHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
           +  V   S C++P       D   +   P  P   +  Y + K   ++L   Y  S+G  
Sbjct: 108 RTTVYTSSACVYPASLQREPDAAPLAEDPVFPAEPDMEYGWEKLTTEILCGAYRRSHGMD 167

Query: 465 FTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDP-TFTVMGSGKPLRQFIY 632
             +     ++GP   ++   +  +  L  ++  A   GD     V G G   R + Y
Sbjct: 168 IKTARLHAIYGPLGTYTGPRAKSLSMLCDKV--ARIPGDEGEIEVWGDGTQTRSYCY 222


>UniRef50_Q9ABX8 Cluster: UDP-glucose 4-epimerase; n=1; Caulobacter
           vibrioides|Rep: UDP-glucose 4-epimerase - Caulobacter
           crescentus (Caulobacter vibrioides)
          Length = 327

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 47/193 (24%), Positives = 82/193 (42%), Gaps = 11/193 (5%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           GD+RD  + +A+FA + P  V+H AA +  +  ++ +   FF  N+     +++A  +  
Sbjct: 50  GDIRDAARLDAVFAAYAPVAVLHFAARI-EVGESVKNPGAFFDTNVGGTITLIEAARRAG 108

Query: 288 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG--- 458
           VK VV   +   F D    P+ ET  H   P +    Y  +K M++     Y+   G   
Sbjct: 109 VKVVVFSSTCATFGDPVDLPMKET--H---PQAPLNPYGRSKLMVEQALADYDRYVGLKS 163

Query: 459 --CMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMG------SGKP 614
               + +    +  G    +    +H +P  I+          P FT+ G       G  
Sbjct: 164 AVMRYFNAAGADPQGRIGEWHEPETHAVPLAIQ----VALGQRPRFTIFGDDYDTRDGTA 219

Query: 615 LRQFIYSLDLARA 653
           +R +++ LDLA A
Sbjct: 220 VRDYVHVLDLADA 232


>UniRef50_Q1VUQ5 Cluster: Sugar epimerase BlmG; n=2; Bacteria|Rep:
           Sugar epimerase BlmG - Psychroflexus torquis ATCC 700755
          Length = 359

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 47/208 (22%), Positives = 78/208 (37%), Gaps = 7/208 (3%)
 Frame = +3

Query: 54  KRNSDYDSETWIFSGSKDGDLRDKTQTEALFAKHKPT---HVIHLAAMVGGLFHNMA--H 218
           K N ++     I     +GDLRD    E  F   +      V  LAA +GG  +     +
Sbjct: 34  KPNHEFWDHQLICDEYMEGDLRDPRIVEKAFENKQNVSYDEVYQLAADMGGALYIFTGEN 93

Query: 219 NLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSN-- 392
           + +    +  IN N+   C K  + +V    S C++P+      D         + +N  
Sbjct: 94  DANVMHNSALINLNVAHECVKNKIGRVFYSSSACMYPEHNQLDADNPNCEESSAYPANPD 153

Query: 393 FGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQ 572
             Y + K   + L   ++ +Y          N+FGP   + +      PA + R      
Sbjct: 154 SEYGWEKLFSERLFLAFSRNYKLSVRVARFHNIFGPMGTW-IGGKEKAPAAMCRKAAETA 212

Query: 573 KGDPTFTVMGSGKPLRQFIYSLDLARAV 656
            G  +  V G GK  R F++  +   AV
Sbjct: 213 DGS-SIEVWGDGKQTRSFLHVDECVEAV 239


>UniRef50_Q0AZA7 Cluster: Nucleoside-diphosphate-sugar epimerase
           precursor; n=1; Syntrophomonas wolfei subsp. wolfei str.
           Goettingen|Rep: Nucleoside-diphosphate-sugar epimerase
           precursor - Syntrophomonas wolfei subsp. wolfei (strain
           Goettingen)
          Length = 328

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 48/190 (25%), Positives = 79/190 (41%), Gaps = 6/190 (3%)
 Frame = +3

Query: 105 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGG--LFHNMAHNLDFFRENMSINDNILQACH 278
           +GD+RD+ +  A  A      +IHLA + G    +H     LD     M    N++ AC 
Sbjct: 54  EGDIRDRERLIA--AARGMDSLIHLAYINGTELFYHQPELVLDVAIRGML---NVIDACR 108

Query: 279 KYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGP-PHSSNFGYSYAKRMIDVLNRGYNESY 455
              + +++   S+ ++ +    P  E +  + P P +  F Y   K   +++   Y    
Sbjct: 109 TEGIGELILASSSEVYQNPPQIPASEAVPLSIPDPLNPRFSYGGGKIACELMAINYGRKD 168

Query: 456 GCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQ---KGDPTFTVMGSGKPLRQF 626
                   P NV+GP     +   HV+P  I R   A++   +G   F + G G   R F
Sbjct: 169 FERVLIFRPHNVYGP----DMGWEHVLPQFILRAIKAIESKPQGPVPFPIQGDGSQTRAF 224

Query: 627 IYSLDLARAV 656
           IY  D   A+
Sbjct: 225 IYIDDFIDAL 234


>UniRef50_Q5V6W4 Cluster: UDP-glucose 4-epimerase; n=1; Haloarcula
           marismortui|Rep: UDP-glucose 4-epimerase - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 309

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 51/183 (27%), Positives = 77/183 (42%)
 Frame = +3

Query: 105 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 284
           +GD+RD+   +A  A      V H AAMV  +  ++   +D    N +   N+   C + 
Sbjct: 56  EGDVRDRETLDA--AIEGVDVVFHEAAMVS-VPESIEQPVDCHELNGTATVNVFD-CARR 111

Query: 285 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
              +VV   S  ++      PI E       P   N  Y + K + +   R Y E YG  
Sbjct: 112 QDTRVVFASSAAVYGVPDDVPIGEDA-----PTEPNSPYGFEKYLGEQYARFYTEEYGLP 166

Query: 465 FTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDL 644
              +   NV+GP      E + VI   +R+     Q G+P  TV G G   R F++  D+
Sbjct: 167 TVPLRYFNVYGP-RGLDGEYAGVIGTFVRQ----AQAGEP-LTVEGDGTQTRDFVHVDDV 220

Query: 645 ARA 653
            RA
Sbjct: 221 VRA 223


>UniRef50_A7DQX9 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Candidatus Nitrosopumilus maritimus SCM1|Rep:
           NAD-dependent epimerase/dehydratase - Candidatus
           Nitrosopumilus maritimus SCM1
          Length = 308

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 42/163 (25%), Positives = 74/163 (45%)
 Frame = +3

Query: 168 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 347
           VIHLAA +  +  ++ H     + N+  + N+L+AC K NVK  ++  S  ++ +    P
Sbjct: 71  VIHLAAKID-ILQSIEHPDQTHKINVEGSLNLLRACVKNNVKNFIAASSAAVYGNPKQIP 129

Query: 348 IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESS 527
           + E  + N  P S    Y   K  ++   R +  +YG    ++   NV+G      L  S
Sbjct: 130 VTEFTIPN--PVSP---YGADKIALEFYLRAFCNAYGINGIALRFFNVYG------LGQS 178

Query: 528 HVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAV 656
           +    +I +  + + +  P   + G GK  R FI+  DL   +
Sbjct: 179 NAYAGVITKFLNQIHQTKP-LRIFGDGKNTRDFIHIDDLVMGI 220


>UniRef50_Q2FKD1 Cluster: NAD-dependent epimerase/dehydratase family
           protein; n=13; Staphylococcus aureus|Rep: NAD-dependent
           epimerase/dehydratase family protein - Staphylococcus
           aureus (strain USA300)
          Length = 326

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 49/187 (26%), Positives = 85/187 (45%), Gaps = 3/187 (1%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN- 287
           D+R+    E +   ++  +VIHLAA+V  +  ++   +     N+     +L+   KYN 
Sbjct: 56  DIREYDAVEQIMKTYQFDYVIHLAALVS-VAESVEKPILSQEINVVATLRLLEIIKKYNN 114

Query: 288 -VKKVVSCLSTCIFPDKTTYP-IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 461
            +K+ +   S  ++ D    P  D++++    P++ +    Y +R    LN  Y   Y  
Sbjct: 115 HIKRFIFASSAAVYGDLPDLPKSDQSLILPLSPYAID--KYYGERT--TLN--YCSLYNI 168

Query: 462 MFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLD 641
               V   NVFGP  +   + S VI     +M D+ +   P FT  G G   R F+Y  D
Sbjct: 169 PTAVVKFFNVFGPRQDPKSQYSGVIS----KMFDSFEHNKP-FTFFGDGLQTRDFVYVYD 223

Query: 642 LARAVHL 662
           + ++V L
Sbjct: 224 VVQSVRL 230


>UniRef50_Q1IM02 Cluster: NAD-dependent epimerase/dehydratase; n=6;
           Bacteria|Rep: NAD-dependent epimerase/dehydratase -
           Acidobacteria bacterium (strain Ellin345)
          Length = 322

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 45/162 (27%), Positives = 77/162 (47%)
 Frame = +3

Query: 168 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 347
           V H AA+   +  ++A  L     N++    +LQA H+  V++V+   S+  + D  T P
Sbjct: 71  VFHEAALAS-VPRSVADPLATNHANVTGTLQLLQAAHRAGVRRVIYAGSSSAYGDTPTLP 129

Query: 348 IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESS 527
            +E M+ N  P S    Y+ +K   +   R     +G    ++   NVFGPY +   + S
Sbjct: 130 KNEEMLAN--PISP---YAVSKLTGEYYLRSMYAVHGMETVTIRYFNVFGPYQDPGSQYS 184

Query: 528 HVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARA 653
            V+   I +    M +G+ T T+ G G+  R F Y  ++ +A
Sbjct: 185 GVLAKFIPQ----MLRGE-TPTIHGDGEQSRDFTYIENVVKA 221


>UniRef50_A3PE63 Cluster: UDP-glucose 4-epimerase; n=1;
           Prochlorococcus marinus str. MIT 9301|Rep: UDP-glucose
           4-epimerase - Prochlorococcus marinus (strain MIT 9301)
          Length = 330

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 49/211 (23%), Positives = 94/211 (44%), Gaps = 16/211 (7%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           D+R+++  + L  K KP +++H AA    +  ++   LD+   N+    ++ + C +  +
Sbjct: 53  DIREESSFKELLLKIKPDYLVHFAAS-AYVSESIFKPLDYISNNIDGMRSVCKICSEIKI 111

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 470
             V S  S  ++ +    PI+E+   N  P S    Y   K   + + +  + +YG  + 
Sbjct: 112 PIVFSS-SCSVYGEAKNVPINESEPLN--PLSP---YGETKLFCEKILKWCSNAYGLRWV 165

Query: 471 SVIPCNVFGPYDNFSL-----ESSHVIPALIRRMDDAMQKGDPTFTVMG------SGKPL 617
           S+   N  G  ++  +       +H+IP  IR + D+ +    T  + G       G  +
Sbjct: 166 SLRYFNAAGADEDLEIGEKHDPETHIIPLAIRALGDSGE----TLKIFGRDYDTFDGTAV 221

Query: 618 RQFIYSLDLARA-----VHLGSSGTTTVSNL 695
           R FI+ +DLA A      +L   G + + NL
Sbjct: 222 RDFIHVMDLASAHLKAIEYLAEGGMSNIFNL 252


>UniRef50_O28263 Cluster: UDP-glucose 4-epimerase; n=1;
           Archaeoglobus fulgidus|Rep: UDP-glucose 4-epimerase -
           Archaeoglobus fulgidus
          Length = 307

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 46/152 (30%), Positives = 74/152 (48%)
 Frame = +3

Query: 141 LFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTC 320
           +F KH+   VIH AA +  +    +H +D FR N+    NIL+AC  ++V+KVV   S  
Sbjct: 50  VFRKHEIEGVIHAAAELS-VKAEKSH-VDAFRANVEGALNILEACRVFDVEKVVFTSSHS 107

Query: 321 IFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGP 500
           ++  + +YP  E   +  P   + F Y   K   ++L   Y+ +YG  F +V    + GP
Sbjct: 108 VYGPR-SYPFTE-FSYRDP---TTF-YGATKACSEILGTYYSYTYGIDFRAVRFPILVGP 161

Query: 501 YDNFSLESSHVIPALIRRMDDAMQKGDPTFTV 596
           +    + +S    +LI   DDA   G    T+
Sbjct: 162 FRR-GMGASVAFSSLI---DDAFFNGTSVITL 189


>UniRef50_Q661H6 Cluster: Nucleotide sugar epimerase; n=3; Borrelia
           burgdorferi group|Rep: Nucleotide sugar epimerase -
           Borrelia garinii
          Length = 355

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 42/185 (22%), Positives = 81/185 (43%), Gaps = 2/185 (1%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQAC--HKY 284
           D+ +K +   LF ++K THV HLAA   G+  ++ +   +   N+    N+L  C  +K 
Sbjct: 76  DILNKDKLLKLFKEYKFTHVCHLAAQ-AGIRDSLENPDSYVSINIVGFFNVLDVCRVYKE 134

Query: 285 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
           N+K  V   ++ ++      P  E  + +   H  N  Y+ +K+  +++   Y+ S+   
Sbjct: 135 NIKHFVYASTSSVYGINENIPSSEDSITD---HPLNL-YAASKKSNEMIAHAYSASFNIP 190

Query: 465 FTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDL 644
            T +    V+G Y    +         +    D ++  +P   +  +G   R F Y  D+
Sbjct: 191 TTGLRFFTVYGTYGRPDM--------ALYLFSDGIKNCEP-INIFNNGNMARDFTYVSDI 241

Query: 645 ARAVH 659
           A  V+
Sbjct: 242 ANGVY 246


>UniRef50_O06485 Cluster: YfnG; n=3; Bacteria|Rep: YfnG - Bacillus
           subtilis
          Length = 301

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 45/176 (25%), Positives = 75/176 (42%), Gaps = 2/176 (1%)
 Frame = +3

Query: 30  TVIERDRQKRNSDYDSETWIFSGSKDGDLRDKTQTEALFAKHKPTHVIHLAAM-VGGLFH 206
           T + RD   +++ Y  E         G L D    E    +++   V HLAA  + G+ +
Sbjct: 13  TGLVRDHVPQSNLYQGEHIKKMNIVRGSLEDLAVIERALGEYEIDTVFHLAAQAIVGVAN 72

Query: 207 NMAHNLDFFRENMSINDNILQACHKYN-VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPH 383
              + +  F  N+    NIL+AC K+  +K+V+   S   + D+   P DE M     P 
Sbjct: 73  R--NPISTFEANILGTWNILEACRKHPLIKRVIVASSDKAYGDQENLPYDENM-----PL 125

Query: 384 SSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESSHVIPALIR 551
                Y  +K   D+++  Y  +YG         N++G  D   L  + +IP  I+
Sbjct: 126 QGKHPYDVSKSCADLISHTYFHTYGLPVCITRCGNLYGGGD---LNFNRIIPQTIQ 178


>UniRef50_Q3ESA4 Cluster: DTDP-glucose 4,6-dehydratase; n=3;
           Firmicutes|Rep: DTDP-glucose 4,6-dehydratase - Bacillus
           thuringiensis serovar israelensis ATCC 35646
          Length = 320

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 48/184 (26%), Positives = 77/184 (41%), Gaps = 4/184 (2%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFR---ENMSIND-NILQAC 275
           GD++DK     LF  +      HLAA +     N+  ++D  R   EN +I   N+L+ C
Sbjct: 56  GDIKDKKLVAQLFENNSFDLCYHLAASI-----NVQDSIDDARATFENDTIGTFNLLEQC 110

Query: 276 HKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESY 455
             Y+VK V   +STC+  DK T   +   +    P      Y+ +K   + +   Y  +Y
Sbjct: 111 LNYDVKMVF--MSTCMVYDKAT---NIQGISELDPIKPASPYAGSKIAAENMVLSYYYAY 165

Query: 456 GCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYS 635
                 + P N +GP+     E   V   +  ++D+          + G GK  R  +Y 
Sbjct: 166 KLPVVVIRPFNTYGPFQKTGGEGGVVAIFINNKLDNV------PLNIYGDGKQTRDLLYV 219

Query: 636 LDLA 647
            D A
Sbjct: 220 EDCA 223


>UniRef50_Q0C2X5 Cluster: UDP-glucose 4-epimerase; n=1; Hyphomonas
           neptunium ATCC 15444|Rep: UDP-glucose 4-epimerase -
           Hyphomonas neptunium (strain ATCC 15444)
          Length = 335

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 51/196 (26%), Positives = 85/196 (43%), Gaps = 10/196 (5%)
 Frame = +3

Query: 105 DGDLRDKTQTEALFAKHKPTHVIHLAA--MVGGLFHNMAHNLDFFRENMSINDNILQACH 278
           +GDL      EA F+  KP  V H AA  +VG    ++     ++R N     N+L A  
Sbjct: 50  EGDLNSPGDIEAAFSAIKPDAVAHFAASTLVG---ESVTEPGKYYRNNTFTTLNVLDAMQ 106

Query: 279 KYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 458
           ++N + ++   +  IF    T    E +  + P +  N  Y  +K M++ +  G++ ++G
Sbjct: 107 RHNTRAIIFSSTCAIFGHAQT----EFLAEDHPKNPIN-PYGMSKLMVEQMLAGFDHAHG 161

Query: 459 CMFTSVIPCNVFGPYDNFSLE------SSHVIPALIRRMDDAMQKGDPTFTVMGS--GKP 614
                +   N  G  D  +L        +H+IP  ++   D       T T   +  G  
Sbjct: 162 IRSACLRYFNAAGA-DRQALTGERHACETHLIPLALKGAYDPGYSFTITGTDFDTPDGTA 220

Query: 615 LRQFIYSLDLARAVHL 662
           LR +I+  DLA A HL
Sbjct: 221 LRDYIHVEDLAEA-HL 235


>UniRef50_A3I4Y7 Cluster: Nucleoside-diphosphate-sugar epimerase and
           GAF domain fusion protein; n=1; Bacillus sp. B14905|Rep:
           Nucleoside-diphosphate-sugar epimerase and GAF domain
           fusion protein - Bacillus sp. B14905
          Length = 308

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 52/203 (25%), Positives = 90/203 (44%)
 Frame = +3

Query: 57  RNSDYDSETWIFSGSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFR 236
           RN D++ ++++ +      + D+   E LF +     VIH AA    +  ++   +    
Sbjct: 39  RNVDFEHKSYLLN------VEDEV-CEHLFKETHFDVVIHCAAQTS-VQQSLQEPVKDIL 90

Query: 237 ENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKR 416
            N+     +L    KY VK  V   S  ++ +    P++ET V    P S    Y   K 
Sbjct: 91  TNIVGLSQMLFLSSKYKVKHFVFASSAAVYGNSHYPPLEETDVCE--PISM---YGLNKS 145

Query: 417 MIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTV 596
           + +     + + Y          NVFGP      E++ VIP++++    +  +G P FT+
Sbjct: 146 IGETYCEKWQKDYRLPILIYRFANVFGPRQQMQGEAA-VIPSMLK----SSMEGKP-FTI 199

Query: 597 MGSGKPLRQFIYSLDLARAVHLG 665
            G G+  R FIY  D+A A++ G
Sbjct: 200 YGDGEQTRDFIYVDDIADAIYAG 222


>UniRef50_Q8THP9 Cluster: DTDP-glucose 4,6-dehydratase; n=3;
           Methanosarcina|Rep: DTDP-glucose 4,6-dehydratase -
           Methanosarcina acetivorans
          Length = 298

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 49/182 (26%), Positives = 77/182 (42%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           GD+ D +  E   A      V H AA+V     +    ++ FR N     N+LQAC +  
Sbjct: 52  GDICDPSSVEK--AVSGMDCVFHEAALVSVPL-SCEKPVEAFRINTLGTLNVLQACVRAG 108

Query: 288 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 467
           V+K V+  S  ++ +    P  E M    P  +S   Y+ +K   + L R + E +G   
Sbjct: 109 VEKFVTASSAAVYGNNPELPKRENMY---PEPAS--PYAISKLDGEYLARMFYEEHGLRT 163

Query: 468 TSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLA 647
           T +   NV+GP  +     + VIP  + R      K      + G G   R F++  D+ 
Sbjct: 164 TCLRYFNVYGPRQDPKSPYAAVIPIFLER-----AKAGKDLVIYGDGLQSRDFVHVKDVV 218

Query: 648 RA 653
            A
Sbjct: 219 MA 220


>UniRef50_A0LGE9 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Syntrophobacter fumaroxidans MPOB|Rep: NAD-dependent
           epimerase/dehydratase - Syntrophobacter fumaroxidans
           (strain DSM 10017 / MPOB)
          Length = 315

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 30/86 (34%), Positives = 43/86 (50%)
 Frame = +3

Query: 399 YSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKG 578
           Y  AK M++     ++  YG  +  V P N FGP  N+  E   VIP   R++ D     
Sbjct: 144 YGVAKLMMEKYLYMFSYLYGLEYIIVRPSNPFGPRQNYMGEQG-VIPIFFRKILD----- 197

Query: 579 DPTFTVMGSGKPLRQFIYSLDLARAV 656
           D T ++ G GK  + ++Y  DLA AV
Sbjct: 198 DETISIWGDGKGTKDYLYVEDLAGAV 223


>UniRef50_A3ERM8 Cluster: UDP-glucose 4-epimerase; n=1;
           Leptospirillum sp. Group II UBA|Rep: UDP-glucose
           4-epimerase - Leptospirillum sp. Group II UBA
          Length = 323

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 45/194 (23%), Positives = 89/194 (45%), Gaps = 9/194 (4%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           GD+RD     +LF+ +    VIH AA +  +  ++   L ++  N++    IL+    + 
Sbjct: 50  GDIRDPRALTSLFSHYPIEAVIHFAAAI-EVGESVQDPLKYWDNNLNGTLRILETMRSFG 108

Query: 288 VKKVVSCLSTCIFPDKTTYPI-DETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
           V+ ++   +  ++  K+  PI +E  +    P+      + A+R+++     +  S   +
Sbjct: 109 VRNLILSSTAAVYSPKSDGPITEEDRIDPQNPYGET--KAAAERLVEACRHAFGVS-SVI 165

Query: 465 FTSVIPCNVFGPYD--NFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKP------LR 620
           F       +   Y   + ++  SH+IPA++    DA+    P   V G+  P      +R
Sbjct: 166 FRYFNAAALEPSYGLVSHAIPRSHLIPAVL----DAISGRIPALRVFGNDYPTPDGTGVR 221

Query: 621 QFIYSLDLARAVHL 662
            +I+ +DLA A HL
Sbjct: 222 DYIHVMDLAEA-HL 234


>UniRef50_Q2FN70 Cluster: NAD-dependent epimerase/dehydratase
           precursor; n=1; Methanospirillum hungatei JF-1|Rep:
           NAD-dependent epimerase/dehydratase precursor -
           Methanospirillum hungatei (strain JF-1 / DSM 864)
          Length = 313

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 47/169 (27%), Positives = 77/169 (45%), Gaps = 4/169 (2%)
 Frame = +3

Query: 168 VIHLAAMVGGLFHNMAHNLDFFRENMSINDN----ILQACHKYNVKKVVSCLSTCIFPDK 335
           + HLAA+V     ++  ++D  R N  IN +    + +A     V K+V   S  ++ + 
Sbjct: 75  IFHLAALV-----SVQRSIDDPRLNHRINIDGLFEVFEAARLARVPKIVLASSAALYGND 129

Query: 336 TTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFS 515
              P  ET      P S    Y+  K + ++    Y + YG     +   NV+GP  + S
Sbjct: 130 YLPPHKETFA--SVPLSP---YAVGKCLSELYAAVYTDLYGVHSVCLRFFNVYGPKQDPS 184

Query: 516 LESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAVHL 662
              S VI   +    DA+ + D  FT+ G G+  R F+Y LD+ +A+ L
Sbjct: 185 SPYSGVISKFM----DAISRDDG-FTIFGDGEQTRDFVYVLDVVQALIL 228


>UniRef50_A7CY79 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Opitutaceae bacterium TAV2|Rep: NAD-dependent
           epimerase/dehydratase - Opitutaceae bacterium TAV2
          Length = 349

 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 43/192 (22%), Positives = 74/192 (38%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           D+RD    E  FA H P H ++  A   G+  ++     +   N+    N+L+AC  ++V
Sbjct: 79  DIRDPAAIERTFATHHPIHAVYHLAARAGVRPSIHSPRLYLSTNIDGTLNLLEACRAHHV 138

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 470
              +   S+ ++      P  ET     P   +   Y+ +K   + L   Y   +G    
Sbjct: 139 PDFILASSSSVYGANPKTPFAET----DPIQRTLSPYAASKLAAEQLCSNYAHLHGLRCL 194

Query: 471 SVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLAR 650
            +    V+GP     L         I R   A++ G P   + G G   R + Y  D+ +
Sbjct: 195 CLRLFTVYGPRQRPDL--------AIARFTAAIRDGRP-IDLYGDGTTARDYTYVDDIIQ 245

Query: 651 AVHLGSSGTTTV 686
            +      T T+
Sbjct: 246 GLLAAGRRTATL 257


>UniRef50_Q57664 Cluster: Putative UDP-glucose 4-epimerase; n=3;
           cellular organisms|Rep: Putative UDP-glucose 4-epimerase
           - Methanococcus jannaschii
          Length = 305

 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 51/185 (27%), Positives = 82/185 (44%), Gaps = 2/185 (1%)
 Frame = +3

Query: 105 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRE-NMSINDNILQACHK 281
           + D+RDK   E +  K     VIH AA +     N   N  +  + N+    NIL+   K
Sbjct: 48  NADIRDKDLDEKINFKDVEV-VIHQAAQIN--VRNSVENPVYDGDINVLGTINILEMMRK 104

Query: 282 YNVKKVVSCLST-CIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 458
           Y++ K+V   S   ++ +    P+DE   H   P S    Y  +K + +   + YN  YG
Sbjct: 105 YDIDKIVFASSGGAVYGEPNYLPVDEN--HPINPLSP---YGLSKYVGEEYIKLYNRLYG 159

Query: 459 CMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSL 638
             +  +   NV+G   +   E+  VI   I +M   ++   P   + G G   R F+Y  
Sbjct: 160 IEYAILRYSNVYGERQDPKGEAG-VISIFIDKM---LKNQSPI--IFGDGNQTRDFVYVG 213

Query: 639 DLARA 653
           D+A+A
Sbjct: 214 DVAKA 218


>UniRef50_Q8KNN2 Cluster: DTDP-D-glucose-4,6-dehydratase; n=4;
           Bacteria|Rep: DTDP-D-glucose-4,6-dehydratase - Aeromonas
           hydrophila
          Length = 379

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 54/198 (27%), Positives = 90/198 (45%), Gaps = 15/198 (7%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY-- 284
           D+ ++ + + +FA+H+P  V+HLAA    +  ++    DF   N+     +L+A   Y  
Sbjct: 76  DICNRAELDRVFAQHQPDAVMHLAAE-SHVDRSITGPADFIETNIVGTYMLLEAARAYWN 134

Query: 285 ---NVKKVV---SCLST------CIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDV 428
               V+K       +ST         PD+    +   +     P++ +  YS +K   D 
Sbjct: 135 GLDEVRKAAFRFHHISTDEVYGDLPHPDEVAPGVALPLFTETTPYAPSSPYSASKASSDH 194

Query: 429 LNRGYNESYGCMFTSVIPC-NVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGS 605
           L R +  +YG + T V  C N +GPY +F      +IP +I    D    G P   V G 
Sbjct: 195 LVRAWRRTYG-LPTIVTNCSNNYGPY-HF---PEKLIPLVILNALD----GKP-LPVYGK 244

Query: 606 GKPLRQFIYSLDLARAVH 659
           G  +R ++Y  D ARA++
Sbjct: 245 GDQIRDWLYVEDHARALY 262


>UniRef50_A3HAA1 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Caldivirga maquilingensis IC-167|Rep: NAD-dependent
           epimerase/dehydratase - Caldivirga maquilingensis IC-167
          Length = 301

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 44/163 (26%), Positives = 74/163 (45%)
 Frame = +3

Query: 168 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 347
           VIH AA +  +  +M    D+ R N+     +   C ++  K +V   S  ++ +    P
Sbjct: 72  VIHAAAYID-VHESMQRPADYVRNNVVGTTVVAHECLRHG-KPMVFISSAAVYGNPVRLP 129

Query: 348 IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESS 527
           I E   H   P S    Y  +K + + + R +    G  F  + P NV+GP  N    S+
Sbjct: 130 IPED--HPLRPISP---YGLSKVLSEEVVRFFG-GLGLRFVILRPFNVYGPGQN----SA 179

Query: 528 HVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAV 656
           +    +I R  + +++G P   + G G   R FI+ LD+AR +
Sbjct: 180 YA--GVIMRFIERVKRGLPP-VIYGDGNQARDFIHVLDVARVI 219


>UniRef50_Q9K6S7 Cluster: UDP-glucose 4-epimerase; n=1; Bacillus
           halodurans|Rep: UDP-glucose 4-epimerase - Bacillus
           halodurans
          Length = 311

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 48/185 (25%), Positives = 76/185 (41%), Gaps = 3/185 (1%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPT-HVIHLAAM--VGGLFHNMAHNLDFFRENMSINDNILQACHK 281
           D+ D+   + +F +H     ++HLAA   VG    N  ++      N+     +L+   K
Sbjct: 52  DILDERVAD-VFQEHPDIDRIVHLAAQSKVGPSVLNPTYDAQV---NIQGTIRLLEFSRK 107

Query: 282 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 461
           Y VK+ V   S  I+    T PI E       P      Y  +K   +   + Y   YG 
Sbjct: 108 YGVKQFVFASSAAIYGPSHTLPIREEF-----PALPLSPYGTSKYAAEAYVKTYGRLYGL 162

Query: 462 MFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLD 641
               +   NV+GP      E+  VI   I ++   ++   P   + G GK  R FI+ LD
Sbjct: 163 NVHVLRFANVYGPRQTAETEAG-VISIFIEKL---LKNEQPI--IFGDGKQTRDFIFVLD 216

Query: 642 LARAV 656
           +  A+
Sbjct: 217 VVNAI 221


>UniRef50_Q65E95 Cluster: Putative uncharacterized protein; n=1;
           Bacillus licheniformis ATCC 14580|Rep: Putative
           uncharacterized protein - Bacillus licheniformis (strain
           DSM 13 / ATCC 14580)
          Length = 309

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 41/165 (24%), Positives = 74/165 (44%)
 Frame = +3

Query: 159 PTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKT 338
           P +++HLAA V  +  +++  L+    N+  + +I++A  + NVKK+V   S  ++ +  
Sbjct: 68  PDYIVHLAAQVS-VAESVSDFLNDENINIRGSLHIIKAAGECNVKKIVFASSAAVYGNPD 126

Query: 339 TYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSL 518
             P+D    H   P S    Y   K  ++   +   + YG  +  +   NV+GP  +   
Sbjct: 127 YLPVDTR--HQTNPGSP---YGLTKLTVENYLKLAYDLYGTEYCILRYSNVYGPRQDAKG 181

Query: 519 ESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARA 653
           E       ++    D +  G     + G G+  R FIY  D+A A
Sbjct: 182 EG-----GVVSIFSDLLTSGKAP-VIFGDGEQSRDFIYVGDVACA 220


>UniRef50_A1HMB7 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           Thermosinus carboxydivorans Nor1|Rep: NAD-dependent
           epimerase/dehydratase - Thermosinus carboxydivorans Nor1
          Length = 307

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 46/171 (26%), Positives = 69/171 (40%)
 Frame = +3

Query: 141 LFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTC 320
           LFA  K   V+HLAA           + D  R N+    N+L+ C ++ V++VV   S  
Sbjct: 60  LFANVKFDGVVHLAAQTSVPVSMDKPDFDC-RVNVLGTVNVLEVCRRFGVRRVVLASSAA 118

Query: 321 IFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGP 500
           ++ D    P+ E       P S    Y  +K   +     Y   +G     +   NV+G 
Sbjct: 119 VYGDGVAVPVREDA--KMAPASV---YGLSKLTAETYLSMYTRLFGLEGVVLRYANVYGE 173

Query: 501 YDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARA 653
                 E   V+     RM     +G+   TV G G   R F+Y+ D+A A
Sbjct: 174 RQGDGGEGG-VVSIFTSRM----ARGE-ALTVYGDGYQTRDFVYAGDVANA 218


>UniRef50_Q5UXR0 Cluster: UDP-glucose 4-epimerase; n=3;
           Halobacteriaceae|Rep: UDP-glucose 4-epimerase -
           Haloarcula marismortui (Halobacterium marismortui)
          Length = 310

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 53/184 (28%), Positives = 78/184 (42%), Gaps = 2/184 (1%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           GD+R+    E+  A      VIHLAA+ G    +   + + F  N    +N+L A  K  
Sbjct: 56  GDIREYGDVES--AMRGVDRVIHLAAITGASSTHERRD-ETFAINYDGTENVLTAAGKLG 112

Query: 288 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 467
           V  VV   S  ++   T+  IDET+     P   N  Y+  K   + L + Y E +    
Sbjct: 113 VDHVVFASSCNVYGRATSTDIDETV----DPDPIN-PYAETKLQSETLLQEYCEEFDMTG 167

Query: 468 TSVIPCNVFG--PYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLD 641
           T++     FG  P   F+L  ++ +    R + D         TV G G   R FI+  D
Sbjct: 168 TALRMATNFGHSPGIRFNLVVNYFV---FRALTDR------PLTVYGDGSNWRPFIHVRD 218

Query: 642 LARA 653
            ARA
Sbjct: 219 AARA 222


>UniRef50_Q2FS05 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           cellular organisms|Rep: NAD-dependent
           epimerase/dehydratase - Methanospirillum hungatei
           (strain JF-1 / DSM 864)
          Length = 343

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 41/179 (22%), Positives = 72/179 (40%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           G + D      LF K+K  +V HL A       +     ++   N+  + N++    K  
Sbjct: 58  GSVSDANLITELFTKYKFEYVYHLGAYAAEGLSHFIRRFNY-TNNLIGSINLINEAVKVG 116

Query: 288 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 467
            K  V   S  ++       I+  M     PH  +  Y  +K  +++     +  +G  +
Sbjct: 117 TKCFVFTSSIAVYG-----AIEPPMTEEKTPHPED-PYGISKLAVELDLMAAHSMFGLNY 170

Query: 468 TSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDL 644
               P NV+G Y N S    +VI   ++++ +    G P  T+ G G+  R F Y  D+
Sbjct: 171 VIFRPHNVYGEYQNLSDPYRNVIGIFMKQIFE----GQP-MTIFGDGEQQRAFSYVGDI 224


>UniRef50_Q12VP0 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Methanococcoides burtonii DSM 6242|Rep: NAD-dependent
           epimerase/dehydratase - Methanococcoides burtonii
           (strain DSM 6242)
          Length = 303

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 41/150 (27%), Positives = 69/150 (46%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           D  D T  E +    K   ++HLA M   +  +  H  D +  N     N+L+ C   +V
Sbjct: 45  DSIDITNWEQVKTIPKRDVLVHLAGMTN-IPESFNHPRDVYTINTFGTLNMLEWCRLNDV 103

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 470
           K+ +   ST ++ +    P+DE   H   P   N  YS +K + + L   Y   YG    
Sbjct: 104 KRFIYA-STFVYGNPQYTPVDEK--H---PTLPNNPYSQSKLIGEELCNAYCRDYGIDVI 157

Query: 471 SVIPCNVFGPYDNFSLESSHVIPALIRRMD 560
           S+   NV+GP+     +  ++IP +IR+++
Sbjct: 158 SLRLFNVYGPHQ----KGDYLIPHIIRQLE 183


>UniRef50_Q982P5 Cluster: UDP-glucose 4-epimerase; n=1;
           Mesorhizobium loti|Rep: UDP-glucose 4-epimerase -
           Rhizobium loti (Mesorhizobium loti)
          Length = 310

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 49/186 (26%), Positives = 81/186 (43%), Gaps = 2/186 (1%)
 Frame = +3

Query: 105 DGDLRDKTQ-TEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHK 281
           +GD RD    T+AL +     H++H +        +MA ++   R+++  +  +L AC +
Sbjct: 49  EGDFRDNLAVTKALQSHDTVIHLVH-STWPSTADADMAADI---RDSVIPSVELLDACVR 104

Query: 282 YNVKKVVSCLSTCIFPDKTTY-PIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 458
             VK+++   S       T Y  +DE  +    P +    Y  +K MI+   R Y   YG
Sbjct: 105 SGVKRIIYFSS-----GGTVYGEVDEIPIREDSPTNPVGAYGVSKLMIEHYVRLYERKYG 159

Query: 459 CMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSL 638
                V   N FGP+    +E+ +    L+      +Q  D   TV G G   R ++Y  
Sbjct: 160 LNSFIVRLANPFGPW---QVEAHN--QGLVAFAGHLIQ-SDRQVTVYGDGSARRDYVYVE 213

Query: 639 DLARAV 656
           D+A  V
Sbjct: 214 DVANFV 219


>UniRef50_Q2SII8 Cluster: Nucleoside-diphosphate-sugar epimerase;
           n=3; Gammaproteobacteria|Rep:
           Nucleoside-diphosphate-sugar epimerase - Hahella
           chejuensis (strain KCTC 2396)
          Length = 319

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 45/173 (26%), Positives = 75/173 (43%), Gaps = 7/173 (4%)
 Frame = +3

Query: 3   SGLVGQAIKTVIERDRQK-RNSDYDSETWIFSGSKDGDLR---DKTQTEALFAKHKPTHV 170
           +G  G   + VI R R+K +    D    ++ G      R   +K   E +F KH  T V
Sbjct: 15  TGAAGALAQQVIARLREKYKVIAVDFREQVYLGDDVPSYRIDVNKRGFEDIFRKHNITGV 74

Query: 171 IHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYPI 350
           IHL  M+    + M      +  N+  +  +L  CHKY+++KV+  LST        Y  
Sbjct: 75  IHLGRMIASEENRMRR----YNSNVLGSHRLLDLCHKYHIQKVI-ILSTYHVYGANAY-- 127

Query: 351 DETMVHNGPP-HSSNFGYSYAKRM-IDVLNRGYNESYGCMFTSVI-PCNVFGP 500
           +  ++  G P  ++         + ++ L   Y   Y  +  +V+ PCN+ GP
Sbjct: 128 NPALIDEGAPLKAAELTMDLIDSVELENLANIYLWKYPDLNITVLRPCNIVGP 180


>UniRef50_Q1VGF9 Cluster: Putative uncharacterized protein; n=1;
           Psychroflexus torquis ATCC 700755|Rep: Putative
           uncharacterized protein - Psychroflexus torquis ATCC
           700755
          Length = 268

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 49/189 (25%), Positives = 84/189 (44%), Gaps = 4/189 (2%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSIN----DNILQAC 275
           GD+RD +   +  A  +   V+HLAA V     ++  +++F +E + IN    DN+L +C
Sbjct: 4   GDVRDASTVHSAVAGCQA--VVHLAAQV-----SVPQSMEFPKETLEINVGGTDNLLNSC 56

Query: 276 HKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESY 455
           +   V + V   S  ++     +P+DE+    G  HS  +  S  +    VL     +  
Sbjct: 57  NINGVSRFVLASSAAVYGTNDAFPLDES--DAGAFHSP-YADSKWQNEQQVLKA---KEA 110

Query: 456 GCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYS 635
           G    ++   NV+G         + VIP  I      +  G    T+ G G   R F++ 
Sbjct: 111 GMEAVALRFFNVYGTGQRADGAYAAVIPKFIE-----LAVGGRAPTIFGDGLQTRDFVHV 165

Query: 636 LDLARAVHL 662
            D+A+A+ L
Sbjct: 166 DDVAQALLL 174


>UniRef50_A4CBV8 Cluster: NAD dependent epimerase/dehydratase family
           protein; n=4; Proteobacteria|Rep: NAD dependent
           epimerase/dehydratase family protein - Pseudoalteromonas
           tunicata D2
          Length = 332

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 44/182 (24%), Positives = 75/182 (41%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           DL D+     LFA  +   VIHLAA   G+ +++ + + +   N+     IL+ C    V
Sbjct: 61  DLADREAIANLFATEQFERVIHLAAQ-AGVRYSIENPMAYIDSNLVGMATILEGCRHNKV 119

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 470
           + +V   S+ ++   T  P  E    + P       Y+  K+  +++   Y+  Y    T
Sbjct: 120 QHLVYASSSSVYGANTKIPFAEEDRVDYPVSL----YAATKKSNELMAHTYSHLYSLPTT 175

Query: 471 SVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLAR 650
            +    V+GP+         + P L     DA+    P   V  +GK  R F Y  D+  
Sbjct: 176 GLRFFTVYGPWGR-----PDMAPFL---FTDAIANDKP-IKVFNNGKMQRDFTYIDDIVE 226

Query: 651 AV 656
            +
Sbjct: 227 GI 228


>UniRef50_Q93N66 Cluster: Dehydratase-like protein; n=14; cellular
           organisms|Rep: Dehydratase-like protein - Coxiella
           burnetii
          Length = 344

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 36/163 (22%), Positives = 70/163 (42%)
 Frame = +3

Query: 165 HVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTY 344
           +V H A  +G +  ++ + +D+ + N+     +L+     NVKK+V   S+      + Y
Sbjct: 75  YVFHFAG-IGDIVPSIENPIDYLQTNVMGTVRVLECARAANVKKLVYAASS------SCY 127

Query: 345 PIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLES 524
            + +       P +  + Y+ +K + +     + + YG    S+   N +G     +   
Sbjct: 128 GLADVPTREDHPIAPQYPYALSKYLGEEAAFHWFQVYGLPVNSIRIFNAYGTRVRTTGVY 187

Query: 525 SHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARA 653
             V     ++     +  D  FTV+G G   R F+Y  D+ARA
Sbjct: 188 GAVFGVFFKQ-----KLADKPFTVVGDGTQRRDFLYVTDVARA 225


>UniRef50_Q6MF46 Cluster: Probable UDP-glucuronat epimerase; n=2;
           cellular organisms|Rep: Probable UDP-glucuronat
           epimerase - Protochlamydia amoebophila (strain UWE25)
          Length = 327

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 37/180 (20%), Positives = 80/180 (44%)
 Frame = +3

Query: 105 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 284
           +GD+++  + +     H+ TH+IHLAA   G+ +++     + + N+    NIL+ C  +
Sbjct: 69  EGDIQNYEKLQNSILLHQTTHLIHLAAQ-AGVRYSLQEPATYLKTNVDGFLNILEICRSH 127

Query: 285 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
              K++   S+ ++   T  P   ++       +S +G +  K+  +++ + Y+  +G  
Sbjct: 128 PHLKLIYASSSSVYGLNTKVPF--SLEDRTDQQASLYGVT--KKTNELMAKTYHHLFGIS 183

Query: 465 FTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDL 644
              +    V+GP+    +       A++        +G P   +   GK  R F Y  D+
Sbjct: 184 SIGLRFFTVYGPWGRPDMAYFSFANAIV--------QGKP-IEIFNEGKMQRDFTYVDDI 234


>UniRef50_Q0LJ11 Cluster: NAD-dependent epimerase/dehydratase; n=4;
           Bacteria|Rep: NAD-dependent epimerase/dehydratase -
           Herpetosiphon aurantiacus ATCC 23779
          Length = 317

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 50/170 (29%), Positives = 64/170 (37%)
 Frame = +3

Query: 156 KPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDK 335
           KP  V+HLAA      H +        EN+    N+L+ C    V  + S  S  ++ D 
Sbjct: 66  KPDVVVHLAA--NAKVHELVTYPHRALENVMTTYNVLEYCRHQQVPIIFSS-SREVYGDI 122

Query: 336 TTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFS 515
             Y  +E         S    YS +K   +     Y   Y   +      NV+G YDN  
Sbjct: 123 HRYLTEEAQADFVYTESP---YSASKISGEAFIYSYARCYNLPYLVFRFSNVYGRYDNDI 179

Query: 516 LESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAVHLG 665
                VIP  IRRM D    G P  TV G  K L  F Y  D    +  G
Sbjct: 180 ERMERVIPLFIRRMRD----GQPV-TVFGREKTL-DFTYVDDCVDGIVRG 223


>UniRef50_A0K2B4 Cluster: NAD-dependent epimerase/dehydratase; n=10;
           Bacteria|Rep: NAD-dependent epimerase/dehydratase -
           Arthrobacter sp. (strain FB24)
          Length = 331

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 38/154 (24%), Positives = 69/154 (44%), Gaps = 2/154 (1%)
 Frame = +3

Query: 258 NILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNR 437
           N+ +A  ++ V K+V+  S  ++     +P  E   H    H+++  Y  AK   + + R
Sbjct: 108 NVFEAAAEHGVGKLVAASSASVYGMAEEFPTSERHHH----HNNDTFYGAAKSFNEGMAR 163

Query: 438 GYNESYGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPL 617
            +    G  +  +   NV+GP  +     + V+   + R+ D    G P   + G G+  
Sbjct: 164 SFRAMTGLDYVLLRYFNVYGPRMDVHGLYTEVLVRWMERIAD----GQPPL-IFGDGRQT 218

Query: 618 RQFIYSLDLARA--VHLGSSGTTTVSNLLSYQLT 713
             FI++ D+ARA  +  GS     V N+ S + T
Sbjct: 219 MDFIHTRDVARANILAAGSGAREGVYNVASGEET 252


>UniRef50_Q01T66 Cluster: DTDP-glucose 4,6-dehydratase precursor;
           n=2; Bacteria|Rep: DTDP-glucose 4,6-dehydratase
           precursor - Solibacter usitatus (strain Ellin6076)
          Length = 339

 Score = 43.2 bits (97), Expect = 0.007
 Identities = 45/184 (24%), Positives = 74/184 (40%), Gaps = 1/184 (0%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           GD+ D    EA  A+ +P  ++H AA    +  ++       R N +    +L+A  +  
Sbjct: 57  GDICDAALVEATLAEERPDAIVHFAA-ESHVDRSILSPEPVVRTNYNGTFTLLEAARRQK 115

Query: 288 VKKVVSCLSTCIFPD-KTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
           + + V   +  ++   +     DE  V N  P S    YS +K   D+L R Y  +Y   
Sbjct: 116 IARFVHVSTDEVYGSLEAPAEADEAYVLN--PSSP---YSASKAASDLLARSYFVTYKLP 170

Query: 465 FTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDL 644
                  N +GPY         +IP +I    D     D    V G G+ +R ++Y  D 
Sbjct: 171 VLITRASNNYGPYQ----FPEKLIPLMIANALD-----DQPLPVYGDGQQVRDWLYVYDH 221

Query: 645 ARAV 656
            R +
Sbjct: 222 CRGI 225


>UniRef50_A6GG02 Cluster: Putative uncharacterized protein; n=1;
           Plesiocystis pacifica SIR-1|Rep: Putative
           uncharacterized protein - Plesiocystis pacifica SIR-1
          Length = 313

 Score = 43.2 bits (97), Expect = 0.007
 Identities = 47/183 (25%), Positives = 76/183 (41%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           GD+R+    E   A      VIHLAA  G +  ++       R N+    N+L AC +  
Sbjct: 53  GDIRELACCE--HAVRDVDAVIHLAAR-GSVPRSIDDPQATMRTNVMGTTNVLDACRRAG 109

Query: 288 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 467
           V++VV   S+ I+      P  E       P S    Y+ +K   + + + ++  +G   
Sbjct: 110 VRRVVQSSSSSIYGVVPGLPRREQ--QRPDPRSP---YAASKLAAEHVAQAWHACWGVEV 164

Query: 468 TSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLA 647
            ++   NV+GP        + V+P  I     A   G P   + G G+  R F Y  D+A
Sbjct: 165 VTLRLFNVYGPRQRSDSSYAAVVPLFIA----AALSGRPA-ELHGGGEQSRAFTYVEDVA 219

Query: 648 RAV 656
             +
Sbjct: 220 EGI 222


>UniRef50_Q5FQW6 Cluster: UDP-glucose 4-epimerase; n=3;
           Bacteria|Rep: UDP-glucose 4-epimerase - Gluconobacter
           oxydans (Gluconobacter suboxydans)
          Length = 328

 Score = 42.7 bits (96), Expect = 0.009
 Identities = 53/200 (26%), Positives = 88/200 (44%), Gaps = 12/200 (6%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAM--VGGLFHNMAHNLDFFRENMSINDNILQACHKY 284
           DL D   T A+ A+ K   V+H AA+  VG    +  H   + R+N     N++Q C ++
Sbjct: 51  DLLDYAATSAVVAQGKWDGVLHFAALSLVGDSMRDPFH---YLRQNYLTALNLVQICVEH 107

Query: 285 NVKKVVSCLSTCIF--PDKTTYPIDETM-VHNGPPHSSNFGYSYAKRMIDVLNRGYNESY 455
            VKK+V   +  +F  P++   PI ET  V  G P+  +      +R++   +  Y    
Sbjct: 108 GVKKIVFSSTAALFGGPERLD-PIPETAPVQPGSPYGES--KFMIERVLHWADAIYGLRS 164

Query: 456 GCM-FTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKP------ 614
            C+ + +    +  G         +H+IP  I    DA     P   + G+  P      
Sbjct: 165 ACLRYFNAAGADPQGRAGEDHRPETHLIPLTI----DAALGRRPALKLFGTDYPTRDGSC 220

Query: 615 LRQFIYSLDLARAVHLGSSG 674
           +R +I+  DLA A H+ + G
Sbjct: 221 VRDYIHVTDLADA-HVRALG 239


>UniRef50_O54385 Cluster: UDP-glucose epimerase; n=11; cellular
           organisms|Rep: UDP-glucose epimerase - Brucella abortus
          Length = 335

 Score = 42.7 bits (96), Expect = 0.009
 Identities = 35/114 (30%), Positives = 52/114 (45%), Gaps = 1/114 (0%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           GD+RD+   E +  +HK T VIH A +   +  +    L ++  N+     +LQA     
Sbjct: 57  GDIRDRALMEQVIKRHKCTAVIHFAGL-KAVGESSEKPLLYYDCNVLGTLRLLQAMEATG 115

Query: 288 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMI-DVLNRGYN 446
           VKK+V   S  ++ D    PI E       P S+   Y   K +I D+L   YN
Sbjct: 116 VKKLVFSSSATVYGDPDKLPITEDQ-----PLSATNPYGRTKLVIEDMLRDLYN 164


>UniRef50_Q4BX31 Cluster: Similar to Nucleoside-diphosphate-sugar
           epimerases; n=2; Chroococcales|Rep: Similar to
           Nucleoside-diphosphate-sugar epimerases - Crocosphaera
           watsonii
          Length = 301

 Score = 42.7 bits (96), Expect = 0.009
 Identities = 42/181 (23%), Positives = 75/181 (41%), Gaps = 2/181 (1%)
 Frame = +3

Query: 120 DKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKV 299
           D TQ   +F+            M   +   +   LD F +N+ +  N+ +   KY VK++
Sbjct: 49  DLTQESDVFSLASLCDQQTAIVMCSAIKRQLGDTLDAFSQNVQMVSNLCRLLEKYPVKRL 108

Query: 300 VSCLSTCIFPDK--TTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTS 473
           +   S  ++ +    T   + T VH   P S   G  Y    +  L + +++        
Sbjct: 109 IYFSSAAVYGEDIHNTNITETTPVH---PTSYYGGAKYTSEFL--LRKQFSKLPESSLVC 163

Query: 474 VIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARA 653
           + P  ++GP D+ S  S       IR    A+ +   T T+ G G  LR+F++  D+ + 
Sbjct: 164 LRPATIYGPGDSGSAYSPS---GFIR---SALNQD--TITLWGDGTELREFLFIEDVVKL 215

Query: 654 V 656
           V
Sbjct: 216 V 216


>UniRef50_A6PTX1 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Victivallis vadensis ATCC BAA-548|Rep: NAD-dependent
           epimerase/dehydratase - Victivallis vadensis ATCC
           BAA-548
          Length = 305

 Score = 42.7 bits (96), Expect = 0.009
 Identities = 46/183 (25%), Positives = 74/183 (40%)
 Frame = +3

Query: 105 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 284
           +GD+RD+       A     +V HLAAM+  +  +M   ++    N +    +L+   K 
Sbjct: 49  EGDIRDRITVAK--AMEDVDYVFHLAAMIS-VPESMTKIIECIDINNTGMLIVLEEAAKA 105

Query: 285 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
            VKK+    S  I+ D    P  ETM     P S    Y+  K   +   + +N++    
Sbjct: 106 GVKKLCFSTSAAIYGDNPVVPKVETMFPE--PKSP---YAITKLDGEYYCKMFNDTGKLK 160

Query: 465 FTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDL 644
              +   NVFGP  +     +  +P        A    +   T+ G G+  R FIY  D+
Sbjct: 161 TACLRYFNVFGPRQDPKSAYAAAVPIF-----TAKAVANEPLTIFGDGEQTRDFIYVKDI 215

Query: 645 ARA 653
             A
Sbjct: 216 VAA 218


>UniRef50_Q93VR3 Cluster: GDP-mannose 3,5-epimerase; n=21; cellular
           organisms|Rep: GDP-mannose 3,5-epimerase - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 377

 Score = 42.7 bits (96), Expect = 0.009
 Identities = 34/158 (21%), Positives = 60/158 (37%), Gaps = 2/158 (1%)
 Frame = +3

Query: 165 HVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTY 344
           HV +LAA +GG+    +++      N  I+ N+++A     +K+     S CI+P+    
Sbjct: 94  HVFNLAADMGGMGFIQSNHSVIMYNNTMISFNMIEAARINGIKRFFYASSACIYPEFKQL 153

Query: 345 PIDETMVHNGP--PHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSL 518
                 +      P      Y   K   + L + YN+ +G         N++GP+  +  
Sbjct: 154 ETTNVSLKESDAWPAEPQDAYGLEKLATEELCKHYNKDFGIECRIGRFHNIYGPFGTWKG 213

Query: 519 ESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIY 632
                  A  R+     Q     F + G G   R F +
Sbjct: 214 GREKAPAAFCRK----AQTSTDRFEMWGDGLQTRSFTF 247


>UniRef50_Q868I5 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=2;
           Giardia intestinalis|Rep: UDP-N-acetylglucosamine
           4-epimerase - Giardia lamblia (Giardia intestinalis)
          Length = 385

 Score = 42.3 bits (95), Expect = 0.011
 Identities = 45/181 (24%), Positives = 79/181 (43%), Gaps = 2/181 (1%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAK--HKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHK 281
           GD+RDK    A+F++   K   VIHLAA V  +  ++ +   +   N+  + N+ Q    
Sbjct: 63  GDIRDK----AIFSRLPQKIDFVIHLAAAVS-VAESVTNPQKYMLTNVEGSRNVFQYAVD 117

Query: 282 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 461
                V+S  +   + D     I E       P+     Y+ +K  ++ L   + ++  C
Sbjct: 118 AKASAVLSASTAAYYGDCGKSAITEAF-----PYGGISPYAESKMEMERLGAEFQKTSRC 172

Query: 462 MFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLD 641
            F      NV+GP  + S   + V+   + R   A +K     T+ G+G+  R F++  D
Sbjct: 173 RFIFCRFFNVYGPRQDPSSPYTGVMSIFMDRC--AARK---PITIFGTGEQTRDFVFIKD 227

Query: 642 L 644
           L
Sbjct: 228 L 228


>UniRef50_Q97KX2 Cluster: Nucleoside-diphosphate-sugar epimerase;
           n=2; Clostridium|Rep: Nucleoside-diphosphate-sugar
           epimerase - Clostridium acetobutylicum
          Length = 315

 Score = 41.9 bits (94), Expect = 0.015
 Identities = 46/173 (26%), Positives = 77/173 (44%), Gaps = 3/173 (1%)
 Frame = +3

Query: 153 HKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPD 332
           +K  ++IHLAA+VG     M   ++  + + +  DN+L+A H YN K +    S+ I+  
Sbjct: 64  NKCDYIIHLAAVVGVRLA-MLKGIEGLKVSCTGTDNMLEAAHLYN-KGIFISSSSAIYGK 121

Query: 333 KTTYPIDETMVH-NGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYD- 506
            +   +DE      G     ++ YS  K   + L   Y+   G         NV GPY  
Sbjct: 122 ISKKSVDEEDDSVLGTSKKPSWLYSVGKLTEEHLVLAYHRELGVKVKIGRFFNVIGPYQV 181

Query: 507 -NFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAVHL 662
            N+ +    V+P  I   + A++  +    V G+G+  R F Y  D+   + L
Sbjct: 182 GNYGM----VVPTFI---NVALE--EKPIQVYGNGQQTRTFGYIEDILNGLQL 225


>UniRef50_Q67KU6 Cluster: UDP-glucose 4-epimerase; n=1;
           Symbiobacterium thermophilum|Rep: UDP-glucose
           4-epimerase - Symbiobacterium thermophilum
          Length = 321

 Score = 41.9 bits (94), Expect = 0.015
 Identities = 48/186 (25%), Positives = 74/186 (39%), Gaps = 5/186 (2%)
 Frame = +3

Query: 138 ALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLST 317
           +L  K KP  ++HLAA V          LD    N+     +L+A  ++ V   V   S 
Sbjct: 64  SLVGKVKPDTIVHLAAQVSVAVSVRDPVLD-ADVNVGGTLRVLEAAREHQVPNFVFSSSA 122

Query: 318 CIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFG 497
            ++   ++ P+ E       P S    Y  AK   +   R Y   +G     +   NVFG
Sbjct: 123 AVYGIPSSLPVTE-----DAPFSPLSPYGIAKVAAEGYIRAYCFLHGLKAVVMRYSNVFG 177

Query: 498 PYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAV-----HL 662
           P    + +       ++    +A+ +G P     G G   R FIY  D+A A      +L
Sbjct: 178 PRQKAAGDG-----GVVANFVEAILRGHPP-VFFGDGGQTRDFIYVKDVADATLKAIDYL 231

Query: 663 GSSGTT 680
             SGT+
Sbjct: 232 DKSGTS 237


>UniRef50_Q9JRN7 Cluster: Putative uncharacterized protein; n=1;
           Aggregatibacter actinomycetemcomitans|Rep: Putative
           uncharacterized protein - Actinobacillus
           actinomycetemcomitans (Haemophilusactinomycetemcomitans)
          Length = 294

 Score = 41.9 bits (94), Expect = 0.015
 Identities = 49/195 (25%), Positives = 89/195 (45%), Gaps = 2/195 (1%)
 Frame = +3

Query: 3   SGLVGQAIKTVIERDRQKRNSDYDSETWIFSGSKDGDLRDKTQTEALFAKHKPTHVIHLA 182
           SG +G   K +I   R+KR    + E +  +  +  DL +    +++  K KP  ++HLA
Sbjct: 9   SGFIG---KNLIYLLREKR----EFEVFGATVEETMDLTNPCSVQSVLEKTKPDFIVHLA 61

Query: 183 AMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKV-VSCLSTC-IFPDKTTYPIDE 356
           A+    F    + + F+  N    +N+L++    NV K+ V C ST  I+  + T  + E
Sbjct: 62  ALT---FVPNNNPITFYLVNTIGTENLLRSIVDLNVAKLGVLCFSTAGIYGIQETKLLSE 118

Query: 357 TMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESSHVI 536
           ++      H     YS +K  ++ +   Y    G   T V P NV G   N +     ++
Sbjct: 119 SLTPKPVNH-----YSMSKHCMEHIVNKYRCFRG--ITVVRPFNVLGLGQNINFLVPKMV 171

Query: 537 PALIRRMDDAMQKGD 581
            A +++ D  ++ G+
Sbjct: 172 SAFVKK-DKTIELGN 185


>UniRef50_A1Y020 Cluster: UDP-glucose 4-epimerase; n=1; Spironucleus
           barkhanus|Rep: UDP-glucose 4-epimerase - Spironucleus
           barkhanus
          Length = 306

 Score = 41.9 bits (94), Expect = 0.015
 Identities = 49/193 (25%), Positives = 79/193 (40%), Gaps = 1/193 (0%)
 Frame = +3

Query: 120 DKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKV 299
           D T T A         V+HLAA +  +  +M +   + R  +  + N+     +   + V
Sbjct: 49  DVTDTSAFDTLSTFDFVVHLAAAIS-VAESMTNPAKYQRSIVEGSRNVFAYAVRTGARAV 107

Query: 300 VSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVI 479
           +S  S  ++ D  T  I E   + G        Y+ AK  ++ +  G   +   +F    
Sbjct: 108 LSASSAAVYGDCGTDAITEAYRYGGISP-----YAQAKYDMEGIPAGDTSATRFIFCRFF 162

Query: 480 PCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDL-ARAV 656
             NVFGP  + S   + V+   I    D   +G P  T+ G G+  R F+Y  DL   A 
Sbjct: 163 --NVFGPRQDPSSPYTGVMSIFI----DRALRGIP-ITIFGDGEQTRDFVYVKDLVCGAF 215

Query: 657 HLGSSGTTTVSNL 695
            L   G + V N+
Sbjct: 216 ALLDGGASGVFNI 228


>UniRef50_Q9LIS3 Cluster: UDP-glucuronate 4-epimerase 6; n=40;
           Viridiplantae|Rep: UDP-glucuronate 4-epimerase 6 -
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 460

 Score = 41.9 bits (94), Expect = 0.015
 Identities = 34/134 (25%), Positives = 58/134 (43%), Gaps = 1/134 (0%)
 Frame = +3

Query: 105 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 284
           +GDL D      LF     TH++HLAA   G+ + M +   +   N++   N+L+     
Sbjct: 169 EGDLNDGPLLRKLFDVVPFTHILHLAAQ-AGVRYAMKNPQSYIASNIAGFVNLLEVAKAA 227

Query: 285 NVK-KVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 461
           N +  +V   S+ ++   T  P  E    + P       Y+  K+  + +   YN  YG 
Sbjct: 228 NPQPAIVWASSSSVYGLNTENPFSEEHRTDQPASL----YAATKKAGEEIAHTYNHIYGL 283

Query: 462 MFTSVIPCNVFGPY 503
             T +    V+GP+
Sbjct: 284 SLTGLRFFTVYGPW 297


>UniRef50_Q2WB63 Cluster: Nucleoside-diphosphate-sugar epimerase;
           n=2; Alphaproteobacteria|Rep:
           Nucleoside-diphosphate-sugar epimerase -
           Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
          Length = 333

 Score = 41.5 bits (93), Expect = 0.020
 Identities = 31/136 (22%), Positives = 60/136 (44%)
 Frame = +3

Query: 261 ILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRG 440
           +L+   K  V + V C S+ ++ +     ++E      P       Y  AK   ++  + 
Sbjct: 104 LLEEARKRQVSRFVYCSSSEVYGNGRDSLLNEDRTVCEPVTV----YGAAKLAGELYAKA 159

Query: 441 YNESYGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLR 620
           Y+ +YG     V P N +GP +++  + + VIP  + R+ + +       T+ G G   R
Sbjct: 160 YHRTYGLPTVVVRPFNSYGPREHYKGQRAEVIPRFLIRVLNGLPP-----TIFGDGSAGR 214

Query: 621 QFIYSLDLARAVHLGS 668
            F Y  + AR + + +
Sbjct: 215 DFTYVTETARGLAMAA 230


>UniRef50_Q7D561 Cluster: NAD-dependent epimerase/dehydratase family
           protein; n=20; Bacteria|Rep: NAD-dependent
           epimerase/dehydratase family protein - Mycobacterium
           tuberculosis
          Length = 322

 Score = 41.5 bits (93), Expect = 0.020
 Identities = 41/173 (23%), Positives = 70/173 (40%), Gaps = 1/173 (0%)
 Frame = +3

Query: 138 ALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLS- 314
           A+  +H+P  V HLAA +  +  ++A        N+     + +A  +  V+K+V   S 
Sbjct: 72  AILEQHRPEVVFHLAAQI-DVRRSVADPQFDAAVNVIGTVRLAEAARQTGVRKIVHTSSG 130

Query: 315 TCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVF 494
             I+     YP  ET      P      Y+  K   ++    +   YG   + + P NV+
Sbjct: 131 GSIYGTPPEYPTPET-----APTDPASPYAAGKVAGEIYLNTFRHLYGLDCSHIAPANVY 185

Query: 495 GPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARA 653
           GP      +  H    ++     A+  G PT  V G G   R +++  D+  A
Sbjct: 186 GP-----RQDPHGEAGVVAIFAQALLSGKPT-RVFGDGTNTRDYVFVDDVVDA 232


>UniRef50_Q1FJC1 Cluster: DTDP-glucose 4,6-dehydratase; n=1;
           Clostridium phytofermentans ISDg|Rep: DTDP-glucose
           4,6-dehydratase - Clostridium phytofermentans ISDg
          Length = 330

 Score = 41.5 bits (93), Expect = 0.020
 Identities = 41/180 (22%), Positives = 78/180 (43%), Gaps = 2/180 (1%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           GD+ DK     +F +     V+HLAA    +  ++  +++FF+ N+     + Q  H   
Sbjct: 60  GDILDKELLTTIFKEEGIDFVVHLAAE-SHVDRSLQSDIEFFQTNVIGTRMLYQVIHNVW 118

Query: 288 VKKVVSCLSTCIFPDKTTYPIDET--MVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 461
              +       +  D+    ++E+   + + P H +N  YS +K   +++   Y ++YG 
Sbjct: 119 KDDISDKRILHVSTDEVYGELEESGQFIEHMPLHPNN-PYSASKAGGEMVAIAYRKTYGL 177

Query: 462 MFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLD 641
                   N FGPY +       +IP  I+       K  P   V G G+ +R++++  D
Sbjct: 178 PIVRTRCSNNFGPYQH----EEKLIPKCIKNC--LNHKKIP---VYGDGENIREWLFVKD 228


>UniRef50_Q11WU7 Cluster: UDP-galactose-4-epimerase; n=1; Cytophaga
           hutchinsonii ATCC 33406|Rep: UDP-galactose-4-epimerase -
           Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
          Length = 319

 Score = 41.5 bits (93), Expect = 0.020
 Identities = 40/176 (22%), Positives = 74/176 (42%)
 Frame = +3

Query: 105 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 284
           +GD+R+    E +    +   VI   A +G +  ++   +     N+  + N+  A  + 
Sbjct: 57  EGDIRNY---EDVVKAVEGIEVISHQAALGSVPRSLKDPMTSNNANVLGSMNVFHAAKES 113

Query: 285 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
              +VV   S+ ++ D    P +E  + N         Y+ +KR I++  + ++  Y   
Sbjct: 114 GADRVVYASSSSVYGDDPGSPKEEDRLGNVLSP-----YAASKRSIELYAKAFSNVYPFR 168

Query: 465 FTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIY 632
           F ++   NVFGP  N     + VIP  I  + +  Q      T+ G G   R F +
Sbjct: 169 FIAMRYFNVFGPRQNAQGAYAAVIPQFITALLNGQQA-----TIFGDGSQTRDFTF 219


>UniRef50_Q0YI68 Cluster: NAD-dependent
           epimerase/dehydratase:Short-chain
           dehydrogenase/reductase SDR:3-beta hydroxysteroid
           dehydrogenase/isomerase:Polysaccharide biosynthesis
           protein CapD:dTDP- 4-dehydrorhamnose
           reductase:Nucleotide sugar epimerase; n=3; cellular
           organisms|Rep: NAD-dependent
           epimerase/dehydratase:Short-chain
           dehydrogenase/reductase SDR:3-beta hydroxysteroid
           dehydrogenase/isomerase:Polysaccharide biosynthesis
           protein CapD:dTDP- 4-dehydrorhamnose
           reductase:Nucleotide sugar epimerase - Geobacter sp.
           FRC-32
          Length = 328

 Score = 41.5 bits (93), Expect = 0.020
 Identities = 41/184 (22%), Positives = 76/184 (41%)
 Frame = +3

Query: 105 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 284
           +GD+RD+    A+F +  P  VIHLAA   G+  ++ + L +   N+    N+L+A    
Sbjct: 64  EGDIRDEEFIRAIFTQELPDAVIHLAA-AAGVRPSIDNPLLYEEVNVRGTMNLLEAAKAI 122

Query: 285 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
            V+  +   S+ ++ +    P  E      P  +    Y+  K+  +++   Y+  Y   
Sbjct: 123 GVRLFLFASSSSVYGNNPKVPFAEA----DPVDNPISPYAATKKAGELICHTYHHLYDIN 178

Query: 465 FTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDL 644
              +    V+GP     L     I   +R     +++G P     G G   R + Y  D+
Sbjct: 179 IACLRFFTVYGPRQRPDL----AISKFVR----LIEQGKP-IPFYGDGSTSRDYTYIGDI 229

Query: 645 ARAV 656
              +
Sbjct: 230 VAGI 233


>UniRef50_Q0BRM8 Cluster: UDP-glucose 4-epimerase; n=2;
           Rhodospirillales|Rep: UDP-glucose 4-epimerase -
           Granulobacter bethesdensis (strain ATCC BAA-1260 /
           CGDNIH1)
          Length = 342

 Score = 41.5 bits (93), Expect = 0.020
 Identities = 47/196 (23%), Positives = 85/196 (43%), Gaps = 10/196 (5%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAA--MVGGLFHNMAHNLDFFRENMSINDNILQACHKY 284
           DL D+T   A  A+ +   V+H AA  +VG    +M   + +  +N ++   ++ AC ++
Sbjct: 65  DLADETTLHATLAEGQWDGVMHFAARSLVG---ESMVDPMLYMNQNAALGFKLIAACVQH 121

Query: 285 NVKKVVSCLSTCIFPDKTTYPIDE-TMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 461
            V + +   +  +F      PIDE   +  G P+  +      +R +   +R +   Y C
Sbjct: 122 KVPRFLLSSTAALFGHHDDTPIDENAAIQPGSPYGES--KLMIERALSWADRIHGLRYAC 179

Query: 462 M-FTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKP------LR 620
           + + +    +  G         +H+IP +I    DA     P   V G   P      +R
Sbjct: 180 LRYFNAAGADPQGRSGEDHDPETHLIPLVI----DAALGLRPEIKVFGHDYPTRDGTCIR 235

Query: 621 QFIYSLDLARAVHLGS 668
            +I+  DLA+A HL +
Sbjct: 236 DYIHVSDLAQA-HLAA 250


>UniRef50_Q2MFR9 Cluster: Putative NDP-(Heptose/hexose) epimerase/
           dehydrogenase; n=1; Streptomyces hygroscopicus subsp.
           hygroscopicus|Rep: Putative NDP-(Heptose/hexose)
           epimerase/ dehydrogenase - Streptomyces hygroscopicus
           subsp. hygroscopicus
          Length = 308

 Score = 41.1 bits (92), Expect = 0.027
 Identities = 49/182 (26%), Positives = 76/182 (41%), Gaps = 2/182 (1%)
 Frame = +3

Query: 120 DKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKV 299
           D+ +   LFA  +P  V HLA M       +A  +     N++    +L A     V +V
Sbjct: 49  DERRLRELFADWRPDVVAHLAGMADARAV-LAEPVAAMDANVTGTAAVLAAAAASGVSRV 107

Query: 300 VSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMI--DVLNRGYNESYGCMFTS 473
           V   S  ++       +DE    + P   S  G+ Y   MI  ++L R +   +G   T 
Sbjct: 108 VIAGSCWVYNAMPVNAVDE----DEPFLPSGAGHFYTTTMIAKELLARDFARLHGLESTV 163

Query: 474 VIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARA 653
           +    V+GP     +    V+ A +R    A   G P  TV G G+  R F++  DLA A
Sbjct: 164 LRYSPVYGP----GMWPGLVVSAFLR----AAAAGGP-LTVFGDGEERRAFLHVHDLAEA 214

Query: 654 VH 659
            +
Sbjct: 215 FY 216


>UniRef50_A1VG42 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           Desulfovibrio vulgaris subsp. vulgaris|Rep:
           NAD-dependent epimerase/dehydratase - Desulfovibrio
           vulgaris subsp. vulgaris (strain DP4)
          Length = 316

 Score = 41.1 bits (92), Expect = 0.027
 Identities = 39/145 (26%), Positives = 61/145 (42%)
 Frame = +3

Query: 234 RENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAK 413
           REN+S   ++L+   +  V+KVV   S      K   P     +    P      Y   K
Sbjct: 95  RENLSGALDLLECVRRTGVRKVVYTSSGGAIYGKHLMP----RISESHPTDPLCSYGIVK 150

Query: 414 RMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFT 593
             ++     Y+E YG  + ++   N FGP      E   VI   + R+     + +P   
Sbjct: 151 LAVEKYLALYHELYGIDYAALRISNPFGPLQRAGAEQG-VIGVFLGRI----LRNEPLH- 204

Query: 594 VMGSGKPLRQFIYSLDLARAVHLGS 668
           V G G  +R +IY  D+ARA+ L +
Sbjct: 205 VWGDGSVVRDYIYVEDVARALVLAA 229


>UniRef50_A0UW76 Cluster: NAD-dependent epimerase/dehydratase; n=3;
           cellular organisms|Rep: NAD-dependent
           epimerase/dehydratase - Clostridium cellulolyticum H10
          Length = 337

 Score = 41.1 bits (92), Expect = 0.027
 Identities = 44/188 (23%), Positives = 78/188 (41%), Gaps = 4/188 (2%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHK-YN 287
           D+ DK + E +F  HK  +V++ AA    +  +M +  +F   N++   N++ A  K + 
Sbjct: 61  DICDKDKIEEIFKLHKIDYVVNFAAE-SHVDRSMTNTKEFIETNITGTVNLMNAAKKAWE 119

Query: 288 VKK---VVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 458
           +++   +       I  D+      E      P +  N  YS +K   D   + Y ++Y 
Sbjct: 120 IREDEYINGVKFLQISTDEVYGSCTECCSEESPLNPHN-PYSCSKAAADFYVKFYWDAYK 178

Query: 459 CMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSL 638
              +     N +GPY         +IP +I    + +        V G G  +R +IY  
Sbjct: 179 FPVSITRSSNNYGPYQY----PEKLIPLMIHNTIENLM-----LPVYGDGMQMRDWIYVE 229

Query: 639 DLARAVHL 662
           D  RA+ L
Sbjct: 230 DNCRAIDL 237


>UniRef50_Q88XK0 Cluster: UDP-glucose 4-epimerase; n=2;
           Lactobacillus plantarum|Rep: UDP-glucose 4-epimerase -
           Lactobacillus plantarum
          Length = 315

 Score = 40.7 bits (91), Expect = 0.035
 Identities = 47/192 (24%), Positives = 79/192 (41%), Gaps = 2/192 (1%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN- 287
           D+R++   + L  + +P ++  LAA V  +  ++    +    N +   N+L+   K N 
Sbjct: 53  DVRNEKFMQQLLQEERPDYIYFLAA-VASVADSIERPAETHSVNQTAVFNMLEYIRKTNL 111

Query: 288 -VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
            +K+ +   S  ++ +    P  E       P S    Y+  K   +     Y E Y   
Sbjct: 112 PIKQFLFTSSAAVYGNLPELPKKEDS--RVDPLSP---YAIDKYATERFVLAYGELYDLP 166

Query: 465 FTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDL 644
              V   NV+GP  N S   S V+  L     D +    P FT+ G G   R F+Y  D+
Sbjct: 167 TVCVRFFNVYGPGQNPSSPYSGVLSILT----DCLNNKKP-FTLYGDGSQTRDFVYVEDV 221

Query: 645 ARAVHLGSSGTT 680
            +A+ L +   T
Sbjct: 222 IQALWLITKSDT 233


>UniRef50_Q5FRS4 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=1;
           Gluconobacter oxydans|Rep: UDP-N-acetylglucosamine
           4-epimerase - Gluconobacter oxydans (Gluconobacter
           suboxydans)
          Length = 322

 Score = 40.7 bits (91), Expect = 0.035
 Identities = 34/133 (25%), Positives = 58/133 (43%), Gaps = 2/133 (1%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTH-VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQAC-HKY 284
           D+      + L A+H     VIHLAA  G + H+M     +   N+     +L+AC H  
Sbjct: 61  DVASPAAMQDLVARHSDLEGVIHLAAQAG-VRHSMVDPYSYVTSNVMGQVALLEACRHLK 119

Query: 285 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
            +  VV   S+ ++    + P  ET     P    +  Y+  KR  ++++  Y   +G  
Sbjct: 120 KLTHVVYASSSSVYGRNQSVPFRETDRVERP----SSVYAVTKRAAELMSESYAYLHGIP 175

Query: 465 FTSVIPCNVFGPY 503
            T +    V+GP+
Sbjct: 176 QTGLRFFTVYGPW 188


>UniRef50_Q9F8M7 Cluster: DTDP-glucose 4,6-dehydratase; n=2;
           Clostridia|Rep: DTDP-glucose 4,6-dehydratase -
           Carboxydothermus hydrogenoformans
          Length = 161

 Score = 40.7 bits (91), Expect = 0.035
 Identities = 26/86 (30%), Positives = 42/86 (48%)
 Frame = +3

Query: 405 YAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDP 584
           Y+K   D+L R Y+ +YG       PCN +GP+         +IP +I++        +P
Sbjct: 6   YSKAAADMLARAYHRTYGFRXIVARPCNNYGPWQ----YPEKLIPVVIKK----ALNNEP 57

Query: 585 TFTVMGSGKPLRQFIYSLDLARAVHL 662
              V G G  +R+++Y  D   AV+L
Sbjct: 58  -IPVYGQGLNVREWLYVDDCIEAVYL 82


>UniRef50_A6QAJ4 Cluster: dTDP-glucose 4,6-dehydratase; n=1;
           Sulfurovum sp. NBC37-1|Rep: dTDP-glucose 4,6-dehydratase
           - Sulfurovum sp. (strain NBC37-1)
          Length = 469

 Score = 40.7 bits (91), Expect = 0.035
 Identities = 29/97 (29%), Positives = 50/97 (51%), Gaps = 2/97 (2%)
 Frame = +3

Query: 378 PHSSNFGYSYAKRMIDVLNRGYNESYG--CMFTSVIPCNVFGPYDNFSLESSHVIPALIR 551
           P++ N  YS +K   D++ R Y E+YG  C+ T+    N +GP  +       +IP +IR
Sbjct: 255 PYAPNSPYSASKASSDMIVRSYVETYGMDCVITNC--SNNYGPKQH----DEKLIPTIIR 308

Query: 552 RMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAVHL 662
           +       G+ +  + G GK +R ++Y LD  + + L
Sbjct: 309 K----ALVGE-SIPIYGDGKNIRDWLYVLDHCKGIDL 340


>UniRef50_Q7UVP4 Cluster: DTDP-glucose-4,6-dehydratase; n=1;
           Pirellula sp.|Rep: DTDP-glucose-4,6-dehydratase -
           Rhodopirellula baltica
          Length = 392

 Score = 40.3 bits (90), Expect = 0.046
 Identities = 44/187 (23%), Positives = 79/187 (42%), Gaps = 5/187 (2%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           D+ D    +A  A ++P  ++HLAA    +  ++     F + N+    N+LQ+  K+  
Sbjct: 69  DITDAAAIDATIADYQPDAIMHLAAE-SHVDRSIDGPGQFIQTNVIGTFNLLQSSLKHYR 127

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNG-----PPHSSNFGYSYAKRMIDVLNRGYNESY 455
                      F   +T  +  ++   G      P++ +  YS +K   D L R + ++Y
Sbjct: 128 SLEADAKDRFRFLHVSTDEVYGSLGDTGLFTETTPYAPHSPYSASKASSDHLARAWQDTY 187

Query: 456 GCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYS 635
           G         N +GPY         +IP  I +      +G+P   V G G+ +R ++Y 
Sbjct: 188 GLPVLVTNCSNNYGPYQ----FPEKLIPVAILK----CLQGEP-IPVYGKGENIRDWLYV 238

Query: 636 LDLARAV 656
            D  RA+
Sbjct: 239 EDHCRAL 245


>UniRef50_Q6EB26 Cluster: Tgh114; n=10; Bacteria|Rep: Tgh114 -
           Campylobacter jejuni
          Length = 343

 Score = 40.3 bits (90), Expect = 0.046
 Identities = 47/192 (24%), Positives = 82/192 (42%), Gaps = 9/192 (4%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFF-RENMSINDNILQACHK- 281
           GD+ D      +F+K+K   VI+ AA       N   N D F + N+    N+L + +K 
Sbjct: 58  GDISDVFLVNEIFSKYKINAVINFAAE--SHVDNSIKNPDIFIKTNIYGTWNLLNSAYKT 115

Query: 282 YNVKKVVSC--LSTCIFPDKTTYPIDETMVHNGP-----PHSSNFGYSYAKRMIDVLNRG 440
           + ++  +         F   +T  +  ++  NG       ++ N  YS +K   D+L R 
Sbjct: 116 WFLEPFLKKDEFKQSFFYQISTDEVYGSLGENGKFTEDNAYAPNSPYSASKASADMLVRS 175

Query: 441 YNESYGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLR 620
           Y+ +YG         N +GP+ +       +IP +IR   +  Q       + G GK +R
Sbjct: 176 YHHTYGLNAVISNCSNNYGPFQH----DEKLIPTIIRNALNNAQ-----IPIYGDGKNIR 226

Query: 621 QFIYSLDLARAV 656
            ++Y  D   A+
Sbjct: 227 DWLYVKDHCVAI 238


>UniRef50_Q1Q482 Cluster: Similar to dTDP-glucose 4,6-dehydratase;
           n=2; Candidatus Kuenenia stuttgartiensis|Rep: Similar to
           dTDP-glucose 4,6-dehydratase - Candidatus Kuenenia
           stuttgartiensis
          Length = 319

 Score = 39.9 bits (89), Expect = 0.061
 Identities = 48/201 (23%), Positives = 84/201 (41%), Gaps = 6/201 (2%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSI--NDNILQACHKY 284
           D+ D    E +F + KP  V H AA         +     +  N++I  + N+ Q  +KY
Sbjct: 51  DICDAKSLEEVFKQIKPEIVNHHAAHANV---RKSVETPVYDANINILGSLNLCQLSNKY 107

Query: 285 NVKKVV-SCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 461
            VKK + +     ++ +    P +E+     PP   +  Y  +K  ++     +++ Y  
Sbjct: 108 RVKKFIYASTGGAVYGEPKQLPANEST----PPEPLSH-YGVSKHTVEHYLHVFHKLYDL 162

Query: 462 MFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAM-QKGDPTFTVMGSGKPLRQFIYSL 638
             T +   NV+GP      +S H    ++    + M Q   PT  + G G   R ++Y  
Sbjct: 163 NVTILRYPNVYGPR-----QSPHGEAGVVAIFSELMLQNKQPT--IFGDGSKTRDYVYVD 215

Query: 639 DLARA--VHLGSSGTTTVSNL 695
           D+ +A    LG  G   + NL
Sbjct: 216 DIVKANIAVLGDIGNGEIYNL 236


>UniRef50_Q81AP5 Cluster: CDP-abequose synthase; n=2; Bacillus
           cereus group|Rep: CDP-abequose synthase - Bacillus
           cereus (strain ATCC 14579 / DSM 31)
          Length = 319

 Score = 39.5 bits (88), Expect = 0.081
 Identities = 29/87 (33%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHN--LDFFRENMSINDNILQACHKY 284
           D+RDK Q +    K  P ++ HLAA   G+  N AH   +     N+    NI+QA    
Sbjct: 60  DIRDKKQVQDAIKKINPDYIFHLAAY--GV--NSAHTDYIHAIETNVIGTCNIIQAAKLV 115

Query: 285 NVKKVVSCLSTCIFPDKTTYPIDETMV 365
           N KK+++  S+  + +K   PI E M+
Sbjct: 116 NCKKIINFGSSSEYGNKME-PIHENML 141


>UniRef50_Q1YMT2 Cluster: UDP-glucose 4-epimerase; n=3;
           Alphaproteobacteria|Rep: UDP-glucose 4-epimerase -
           Aurantimonas sp. SI85-9A1
          Length = 341

 Score = 39.5 bits (88), Expect = 0.081
 Identities = 49/215 (22%), Positives = 97/215 (45%), Gaps = 17/215 (7%)
 Frame = +3

Query: 102 KDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHK 281
           + GD+RD  +  ++F++++P  +IH A ++  +  ++   L F+  N+S   +++ A   
Sbjct: 55  EQGDIRDTNRLRSVFSQYQPDAIIHFAGLI-EVAQSVRDPLAFYDNNVSGTLSLITAAEA 113

Query: 282 YNVKKVVSCLSTCIFPDKTTYPIDE-TMVHNGPPHSSNFGYSYAKRMIDVLNRGYN--ES 452
             V K+V   STC      TY I + T +      +    Y ++K +++ + R  +  + 
Sbjct: 114 AGVDKIVFS-STC-----ATYGIPQFTPLTEDHVQAPISPYGWSKLLVEHILRDLSGLDR 167

Query: 453 YGCMFTSVIPCNVFGP---YDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMG------S 605
             C            P      +    +H +P +I   + A+ + D  FT+ G       
Sbjct: 168 IRCAILRYFNAAGADPEARIGEWHTPETHAVPLVI---ETALGQRD-CFTIFGDDYDTAD 223

Query: 606 GKPLRQFIYSLDLA----RAV-HLGSSGTTTVSNL 695
           G  +R +++ +DLA    RAV +L + G +   NL
Sbjct: 224 GTCIRDYVHVIDLADAHVRAVEYLLNDGASVALNL 258


>UniRef50_A6GE58 Cluster: NAD-dependent epimerase/dehydratase family
           protein; n=1; Plesiocystis pacifica SIR-1|Rep:
           NAD-dependent epimerase/dehydratase family protein -
           Plesiocystis pacifica SIR-1
          Length = 360

 Score = 39.5 bits (88), Expect = 0.081
 Identities = 47/190 (24%), Positives = 80/190 (42%), Gaps = 3/190 (1%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPT-HVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           D+RD        A+     HV+H AA V  +   +A        N+    N+L+A     
Sbjct: 81  DVRDPEALRQACARFDGVEHVLHHAA-VASVPRTLAEPETAHSVNVDGMFNLLEAARACG 139

Query: 288 VKKVVSCLSTCIFPDKTTYPID--ETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 461
            K VV   S+ ++ D    P    ++    G P S    Y+  KR+ +VL + ++ ++G 
Sbjct: 140 AKSVVHATSSAVYGDCPGAPETGAQSEAIIGRPLSP---YAGQKRIAEVLGQTWSTTHGM 196

Query: 462 MFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLD 641
               +   N+ GP  + +   + VIP  I    D + +G+    + G G   R F    D
Sbjct: 197 SVVGLRYFNIVGPRQDPNGAYAAVIPKWI----DTLARGEQP-VIFGDGLTTRDFCPVED 251

Query: 642 LARAVHLGSS 671
           + +A  L S+
Sbjct: 252 VVQANLLAST 261


>UniRef50_A6DF55 Cluster: Putative uncharacterized protein; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Putative
           uncharacterized protein - Lentisphaera araneosa HTCC2155
          Length = 298

 Score = 39.5 bits (88), Expect = 0.081
 Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 3/136 (2%)
 Frame = +3

Query: 102 KDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHK 281
           + GD+ DK     L  K+  TH++H AA+        A+     + N+    N+L+A  +
Sbjct: 48  EQGDILDKESILRLLQKYAVTHLLHTAAL--RTSQCKANPEQAVQVNIIGTANVLEAIRE 105

Query: 282 Y-NVKKVVSCLSTCIF--PDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNES 452
           Y  ++ VV   +  ++  P   T P DE    N P  + N  Y+  K   + L   Y  S
Sbjct: 106 YAKLEHVVFISTAAVYKVPKDGTRP-DE----NSPVEALNL-YTSTKLAGEALVESYAHS 159

Query: 453 YGCMFTSVIPCNVFGP 500
           YG   + + P  ++GP
Sbjct: 160 YGLQCSVLRPQIIYGP 175


>UniRef50_A5M424 Cluster: UDP-glucose 4-epimerase; n=1;
           Streptococcus pneumoniae SP11-BS70|Rep: UDP-glucose
           4-epimerase - Streptococcus pneumoniae SP11-BS70
          Length = 342

 Score = 39.5 bits (88), Expect = 0.081
 Identities = 30/107 (28%), Positives = 48/107 (44%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           DL+++ + E +F +H    VIH A     +  ++   L ++  N+    NIL+   KY V
Sbjct: 61  DLKNEEKLENVFKRHNFDGVIHFAGYKA-VGESVVEPLKYYENNLLSTINILKLMKKYKV 119

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVL 431
              V   S  ++      P  ET     P  +SN  Y   K+ I+VL
Sbjct: 120 FNFVFSSSATVYESTPIMPFYET----NPLKASN-PYGRTKQYIEVL 161


>UniRef50_Q8ECF4 Cluster: DTDP-glucose 4,6-dehydratase; n=18;
           Gammaproteobacteria|Rep: DTDP-glucose 4,6-dehydratase -
           Shewanella oneidensis
          Length = 375

 Score = 39.1 bits (87), Expect = 0.11
 Identities = 36/148 (24%), Positives = 60/148 (40%), Gaps = 1/148 (0%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           D+ D+T+ E +F+ H+P  V+HLAA    +  ++  + DF + N+     +L+A   Y +
Sbjct: 58  DICDRTELERVFSLHQPDAVMHLAA-ESHVDRSITGSADFIQTNIVGTYTLLEAARHYWM 116

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAK-RMIDVLNRGYNESYGCMF 467
           +      S   F   +T  +   + H   P   N   S       D        S   +F
Sbjct: 117 QLNTERKSAFRFHHISTDEVYGDLPH---PDEINVECSMLNDECKDHSTLNIQHSTLPLF 173

Query: 468 TSVIPCNVFGPYDNFSLESSHVIPALIR 551
           T   P     PY      S H++ A +R
Sbjct: 174 TETTPYTPSSPYSASKASSDHLVRAWLR 201


>UniRef50_Q2WB32 Cluster: Nucleoside-diphosphate-sugar epimerase;
           n=3; Magnetospirillum|Rep: Nucleoside-diphosphate-sugar
           epimerase - Magnetospirillum magneticum (strain AMB-1 /
           ATCC 700264)
          Length = 353

 Score = 39.1 bits (87), Expect = 0.11
 Identities = 40/160 (25%), Positives = 62/160 (38%), Gaps = 1/160 (0%)
 Frame = +3

Query: 165 HVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIF-PDKTT 341
           +VIH AA +   F+  AH L      ++    +L+   ++N +      S     PD   
Sbjct: 101 YVIH-AAGIASPFYYRAHPLATLEVAITGTRRMLELAQEHNARFTFFSSSEIYGDPDPKH 159

Query: 342 YPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLE 521
            P  E+   +         Y  +KR+ + L   ++  +G    ++ P NVFGP       
Sbjct: 160 VPTPESYRGHVSCQGPRACYDESKRVGETLCYIFHGEHGTKTNTIRPFNVFGP--GMQET 217

Query: 522 SSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLD 641
              V+P    R+     KG     V GSG   R F Y  D
Sbjct: 218 DYRVLPNFANRI-----KGGHPLNVYGSGNQTRTFCYITD 252


>UniRef50_Q54WS6 Cluster: Putative dTDP-D-glucose 4,6-dehydratase;
           n=1; Dictyostelium discoideum AX4|Rep: Putative
           dTDP-D-glucose 4,6-dehydratase - Dictyostelium
           discoideum AX4
          Length = 434

 Score = 39.1 bits (87), Expect = 0.11
 Identities = 44/190 (23%), Positives = 77/190 (40%), Gaps = 8/190 (4%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           G++ D    E +F K K   VIHLAA    + ++   ++ F   N+     +L+ C  Y 
Sbjct: 67  GNILDSELLENIFEKEKIDIVIHLAAYT-HVDNSFKQSIKFTENNILGTHYLLETCKNYK 125

Query: 288 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSN--------FGYSYAKRMIDVLNRGY 443
           +KK +   +  ++        D+   +N    SSN          YS +K   + L + Y
Sbjct: 126 LKKFIYVSTDEVYGSGLIEDNDDN--NNSINQSSNEKSILNPTNPYSASKAGAEHLVQSY 183

Query: 444 NESYGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQ 623
            +S+          N++GP          +IP  I      +   +   T+ G+GK  R 
Sbjct: 184 YKSFKLPVIITRANNIYGP----KQYPEKIIPKFIN-----LLLNNKKCTIHGTGKNTRN 234

Query: 624 FIYSLDLARA 653
           ++Y  D+  A
Sbjct: 235 YLYIDDIVSA 244


>UniRef50_Q93KX6 Cluster: Putative UDP-glucose 4-epimerase; n=1;
           Streptomyces viridochromogenes|Rep: Putative UDP-glucose
           4-epimerase - Streptomyces viridochromogenes
          Length = 322

 Score = 38.7 bits (86), Expect = 0.14
 Identities = 42/182 (23%), Positives = 76/182 (41%), Gaps = 1/182 (0%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           D+ D    +      +P  + HLAA +          +D  R N+    N+L+A H    
Sbjct: 61  DVTDAAALDEAVRSARPDVICHLAAQIDVRVSVATPAVDA-RVNVEGTINVLEAAHAVGA 119

Query: 291 KKVVSCLSTCIFPDKTTYPIDE-TMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 467
           + V +     ++ +    P +E T+   G P+ +      A++ I + NR +   +  + 
Sbjct: 120 RVVFASTGGALYGEGVPVPTNEDTLPRPGAPYGT--AKYCAEKYIGLFNRLHGTEHSVLR 177

Query: 468 TSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLA 647
                 NV+GP  +   E+  +  A+   +  A + G PT  V G G   R ++Y  D+A
Sbjct: 178 LG----NVYGPRQSPGGEAGVI--AIYCGL--ASEGGVPT--VFGDGSQTRDYVYVGDVA 227

Query: 648 RA 653
            A
Sbjct: 228 AA 229


>UniRef50_Q3E561 Cluster: NAD-dependent
           epimerase/dehydratase:Short-chain
           dehydrogenase/reductase SDR:3-beta hydroxysteroid
           dehydrogenase/isomerase:Polysaccharide biosynthesis
           protein CapD:dTDP- 4-dehydrorhamnose
           reductase:NmrA-like:Nucleotide sugar epimerase; n=1;
           Chloroflexus aurantiacus J-10-fl|Rep: NAD-dependent
           epimerase/dehydratase:Short-chain
           dehydrogenase/reductase SDR:3-beta hydroxysteroid
           dehydrogenase/isomerase:Polysaccharide biosynthesis
           protein CapD:dTDP- 4-dehydrorhamnose
           reductase:NmrA-like:Nucleotide sugar epimerase -
           Chloroflexus aurantiacus J-10-fl
          Length = 337

 Score = 38.7 bits (86), Expect = 0.14
 Identities = 45/165 (27%), Positives = 67/165 (40%)
 Frame = +3

Query: 168 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 347
           V HLA +  G+ H++    +    N +    +L    + +V + V   S+ ++      P
Sbjct: 75  VYHLACL--GVRHSLHDPFENHDVNATGTLILLDLARRADVPRFVYVSSSEVYGTARWVP 132

Query: 348 IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESS 527
           + E   H   P +    Y   K   +   R + ESY      V P N FGP  +   +S 
Sbjct: 133 MTEE--HPTYPMTV---YGGGKLAGECYTRAFWESYRYPTVVVRPFNSFGPRSHHEGDSG 187

Query: 528 HVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAVHL 662
            VIP  + R   AM  G P   + G G   R F Y  D AR + L
Sbjct: 188 EVIPKFMLR---AM-AGLP-MVIFGDGTQTRDFTYVSDTARGIML 227


>UniRef50_Q1GKR7 Cluster: UDP-glucose 4-epimerase; n=17;
           Bacteria|Rep: UDP-glucose 4-epimerase - Silicibacter sp.
           (strain TM1040)
          Length = 327

 Score = 38.7 bits (86), Expect = 0.14
 Identities = 44/204 (21%), Positives = 84/204 (41%), Gaps = 12/204 (5%)
 Frame = +3

Query: 90  FSGSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQ 269
           F   + GDL D+ + + +FA++KP  V+H AA+   +   M+    ++  N+  +  +++
Sbjct: 44  FGPFEQGDLTDRGRLDEVFAQYKPVAVMHFAAL-SQVGEAMSEPGRYWANNVGGSLCLIE 102

Query: 270 ACHKYNVKKVVSCLSTCIFPDKTTY-PIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYN 446
           A           CL         TY   D  ++    P      Y  +KR ++ + + + 
Sbjct: 103 AA------VAAGCLDFVFSSTCATYGEHDNVVLDENTPQQPLNAYGASKRAVEDILKDFE 156

Query: 447 ESYGCMFTSVIPCNVFG-----PYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGS-- 605
            ++G         NV G         F    +H++P +I+    A++      TV G+  
Sbjct: 157 AAHGLRSVIFRYFNVAGADPEAEVGEFHQPETHLVPLMIQ----AIKGERAALTVFGTDY 212

Query: 606 ----GKPLRQFIYSLDLARAVHLG 665
               G  +R +++  DL  A  LG
Sbjct: 213 DTPDGTCIRDYVHVCDLVDAHILG 236


>UniRef50_Q42605 Cluster: UDP-glucose 4-epimerase; n=20;
           Viridiplantae|Rep: UDP-glucose 4-epimerase - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 351

 Score = 38.7 bits (86), Expect = 0.14
 Identities = 24/83 (28%), Positives = 39/83 (46%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           GDLR+K   E LF+K +   VIH A +   +  ++ +   +F  N+    N+ +   KYN
Sbjct: 67  GDLRNKGDIEKLFSKQRFDAVIHFAGL-KAVGESVENPRRYFDNNLVGTINLYETMAKYN 125

Query: 288 VKKVVSCLSTCIFPDKTTYPIDE 356
            K +V   S  ++      P  E
Sbjct: 126 CKMMVFSSSATVYGQPEKIPCME 148


>UniRef50_UPI0000DAE763 Cluster: hypothetical protein
           Rgryl_01001156; n=1; Rickettsiella grylli|Rep:
           hypothetical protein Rgryl_01001156 - Rickettsiella
           grylli
          Length = 341

 Score = 38.3 bits (85), Expect = 0.19
 Identities = 21/84 (25%), Positives = 42/84 (50%)
 Frame = +3

Query: 105 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 284
           +GD+ D    + +F ++  + VIHLA +   +  ++ + L  +  N+     ++ A  K 
Sbjct: 58  EGDILDSNLLDHIFFENNISAVIHLAGL-KAVSESIKNPLKCYNNNVEGTLTLINAMRKS 116

Query: 285 NVKKVVSCLSTCIFPDKTTYPIDE 356
           NVKK++   S  ++ +    PI E
Sbjct: 117 NVKKLIFSSSAAVYGEPKCVPIRE 140


>UniRef50_Q9RSC3 Cluster: UDP-glucose 4-epimerase; n=1; Deinococcus
           radiodurans|Rep: UDP-glucose 4-epimerase - Deinococcus
           radiodurans
          Length = 394

 Score = 38.3 bits (85), Expect = 0.19
 Identities = 33/141 (23%), Positives = 58/141 (41%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           GDL D     A     KP  +IH AA++  +  +M     ++R N+    N+LQ+  +  
Sbjct: 50  GDLLDAASIRAALEAQKPDAIIHFAALI-EVGESMRAPGRYYRNNVVGTLNLLQSIVETR 108

Query: 288 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 467
              +V   +  ++      PI E       P S    Y   KRM + +   ++ ++G  +
Sbjct: 109 KVPLVFSSTAAVYGTTDAVPIPEDAAMQ--PESV---YGETKRMSEQMIHAFHVAHGLPY 163

Query: 468 TSVIPCNVFGPYDNFSLESSH 530
           T +   NV G      +  +H
Sbjct: 164 TVLRYFNVCGAAPGGDIGEAH 184


>UniRef50_Q8GP51 Cluster: Eps11G; n=11; Bacteria|Rep: Eps11G -
           Streptococcus thermophilus
          Length = 357

 Score = 38.3 bits (85), Expect = 0.19
 Identities = 30/132 (22%), Positives = 61/132 (46%), Gaps = 1/132 (0%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQAC-HKY 284
           G++ D      LF K+KP+ V++LAA    + +++ +   +   N+    NIL+AC H  
Sbjct: 78  GNIADTELITELFEKYKPSVVVNLAAQ-ADVRYSITNPDAYVESNLVSFFNILEACRHCE 136

Query: 285 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
           +++ +V   S+ ++      P       + P       Y+  K+  +++   Y++ Y   
Sbjct: 137 SLEHLVYASSSSVYGSNKKVPYSTDDKVDNPVSL----YAATKKSNELMAHAYSKLYNIP 192

Query: 465 FTSVIPCNVFGP 500
            T +    V+GP
Sbjct: 193 STGLRFFTVYGP 204


>UniRef50_A0UVI4 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Clostridium cellulolyticum H10|Rep: NAD-dependent
           epimerase/dehydratase - Clostridium cellulolyticum H10
          Length = 309

 Score = 38.3 bits (85), Expect = 0.19
 Identities = 44/187 (23%), Positives = 79/187 (42%), Gaps = 4/187 (2%)
 Frame = +3

Query: 105 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSIN----DNILQA 272
           +GD+RD  + E +        V H AA V     ++ ++    +E M IN     NIL+ 
Sbjct: 50  EGDIRDSKKIEEVL--EGVDVVFHNAAFV-----SIRNSYTMLKEEMDINCYGTQNILEG 102

Query: 273 CHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNES 452
             K  V+K+V   S   +      PI E    +  P S    Y ++K   ++  + + + 
Sbjct: 103 MVKQRVRKIVFASSMAAYGWPRQIPITEDC--DLAPISP---YGFSKARCELYCKIFAKR 157

Query: 453 YGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIY 632
           +G  +  +  CN++G         S  +  L   ++ A+       TV G G+ ++ F+ 
Sbjct: 158 FGISYVILRYCNIYG----IKQTLSPYVGVLTTFINQAL--SSQPITVNGDGEQIKDFVN 211

Query: 633 SLDLARA 653
             D+A A
Sbjct: 212 VEDIAHA 218


>UniRef50_Q8WUS8 Cluster: HSPC105 protein; n=21; Euteleostomi|Rep:
           HSPC105 protein - Homo sapiens (Human)
          Length = 383

 Score = 38.3 bits (85), Expect = 0.19
 Identities = 46/194 (23%), Positives = 84/194 (43%), Gaps = 7/194 (3%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRE-NMSINDNILQACHKY 284
           GD+R  +  E  F     T V H+A+   G+      N +  +E N+   DNILQ C + 
Sbjct: 56  GDIRHLSDVEKAFQDADVTCVFHIASY--GMSGREQLNRNLIKEVNVRGTDNILQVCQRR 113

Query: 285 NVKKVV-SCLSTCIFPDKTTYPIDETM----VHNGPPHSSNFGYSYAKRMIDVLNRGYNE 449
            V ++V +     IF  +     DE++    +H  P H S       +++++      + 
Sbjct: 114 RVPRLVYTSTFNVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDR 173

Query: 450 SYGCMFTSVI-PCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQF 626
             G + T  + P  ++GP      E  H +P ++  ++  + K      V G  + L +F
Sbjct: 174 GDGVLRTCALRPAGIYGPG-----EQRH-LPRIVSYIEKGLFK-----FVYGDPRSLVEF 222

Query: 627 IYSLDLARAVHLGS 668
           ++  +L +A  L S
Sbjct: 223 VHVDNLVQAHILAS 236


>UniRef50_A5DWB0 Cluster: Putative uncharacterized protein; n=2;
           Saccharomycetales|Rep: Putative uncharacterized protein
           - Lodderomyces elongisporus (Yeast) (Saccharomyces
           elongisporus)
          Length = 328

 Score = 38.3 bits (85), Expect = 0.19
 Identities = 28/88 (31%), Positives = 45/88 (51%)
 Frame = +3

Query: 399 YSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKG 578
           YS +K + D+L + Y +S+    T + P NVFGP + F      +IP +++      Q G
Sbjct: 157 YSASKALADLLIQAYKQSFQLPITIIRPNNVFGP-NQFP---EKLIPLVMQ----CGQTG 208

Query: 579 DPTFTVMGSGKPLRQFIYSLDLARAVHL 662
                + G+GK  R F+Y  DL  A+ +
Sbjct: 209 KKV-PIHGTGKNKRLFLYISDLLDAIEM 235


>UniRef50_Q984R2 Cluster: DTDP-glucose 4-6-dehydratase; n=8;
           Proteobacteria|Rep: DTDP-glucose 4-6-dehydratase -
           Rhizobium loti (Mesorhizobium loti)
          Length = 346

 Score = 37.9 bits (84), Expect = 0.25
 Identities = 37/150 (24%), Positives = 63/150 (42%), Gaps = 3/150 (2%)
 Frame = +3

Query: 204 HNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPH 383
           H  A  +  F+ ++  + N+L+   + N K +    ++ ++ D   +P  E+   N   H
Sbjct: 104 HYQADPIHTFKTSVLGSLNLLELARRSNAK-IFQASTSEVYGDPLVHPQPESYFGNVNTH 162

Query: 384 SSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPY---DNFSLESSHVIPALIRR 554
                Y   KR  + L   Y+ +YG         N +G     D+  + S+ ++ AL  R
Sbjct: 163 GPRSCYDEGKRSAETLFFDYSRTYGLDIRVARIFNTYGRRMQPDDGRVVSNFIVQAL--R 220

Query: 555 MDDAMQKGDPTFTVMGSGKPLRQFIYSLDL 644
            +D         TV GSG   R F Y+ DL
Sbjct: 221 GED--------LTVYGSGLQTRSFCYADDL 242


>UniRef50_Q7WNH4 Cluster: Putative NAD dependent
           epimerase/dehydratase; n=1; Bordetella
           bronchiseptica|Rep: Putative NAD dependent
           epimerase/dehydratase - Bordetella bronchiseptica
           (Alcaligenes bronchisepticus)
          Length = 335

 Score = 37.9 bits (84), Expect = 0.25
 Identities = 21/65 (32%), Positives = 32/65 (49%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           GD+RD  +  A+FA+H  T V+H AA+  GL    A        N+     +L A     
Sbjct: 55  GDVRDGARLRAVFAQHGITDVVHGAAITAGLERERAQPHAVIEVNLLGTLEVLAAAASCG 114

Query: 288 VKKVV 302
           +++VV
Sbjct: 115 IRRVV 119


>UniRef50_Q93KW6 Cluster: Putative NDP-glucose 4-epimerase; n=1;
           Streptomyces viridochromogenes|Rep: Putative NDP-glucose
           4-epimerase - Streptomyces viridochromogenes
          Length = 342

 Score = 37.9 bits (84), Expect = 0.25
 Identities = 39/183 (21%), Positives = 76/183 (41%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           G + D    + LFA+ +  HV H AA       +   +L+ +  N+  + N++ A  +  
Sbjct: 51  GSVTDVELVDRLFAEQRFDHVFHFAAFAAEAISHSVKSLN-YGTNVMGSVNLINAALRTG 109

Query: 288 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 467
           V       S  ++    T P+ E+ +   P  + ++G   AK  ++        + G  F
Sbjct: 110 VSFFCFASSVAVYGHGET-PMRESSI---PVPADSYG--NAKLTVERELETTMRTQGLPF 163

Query: 468 TSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLA 647
           T+    NV+G + N      + +     +    + +G+P  +V G G  +R F Y  D+ 
Sbjct: 164 TAFRMHNVYGEWQNMRDPYRNAVAIFFNQ----ILRGEP-ISVYGDGGQVRAFSYVKDIV 218

Query: 648 RAV 656
             +
Sbjct: 219 DVI 221


>UniRef50_Q4HQ86 Cluster: UDP-glucose 4-epimerase, putative; n=2;
           Proteobacteria|Rep: UDP-glucose 4-epimerase, putative -
           Campylobacter upsaliensis RM3195
          Length = 323

 Score = 37.9 bits (84), Expect = 0.25
 Identities = 35/131 (26%), Positives = 57/131 (43%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           GDLRD    ++L        V+HL A++   +   A    +   N+    N+L+A  ++ 
Sbjct: 57  GDLRDSFFCDSLVKGVDA--VLHLGALIAIPYSYTAPQ-SYVDTNIQGTLNLLEASKRHG 113

Query: 288 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 467
           VK+ +   ++ ++      PIDE   H   P S    YS +K   D+L   Y  S+    
Sbjct: 114 VKRFIHTSTSEVYGSAIYTPIDEK--HPLQPQSP---YSASKIGADMLALSYFYSFNLPV 168

Query: 468 TSVIPCNVFGP 500
               P N +GP
Sbjct: 169 IVARPFNAYGP 179


>UniRef50_Q1QD53 Cluster: NAD-dependent epimerase/dehydratase; n=3;
           Bacteria|Rep: NAD-dependent epimerase/dehydratase -
           Psychrobacter cryohalolentis (strain K5)
          Length = 333

 Score = 37.9 bits (84), Expect = 0.25
 Identities = 39/176 (22%), Positives = 73/176 (41%), Gaps = 2/176 (1%)
 Frame = +3

Query: 135 EALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN-VKKVVSCL 311
           E +    K + +   AA + G+ + +   +     NM    N L+A H+   V++ +   
Sbjct: 65  EKIIEAAKGSEIFIHAAAIAGIDNTVKSPVRTMTVNMIGTANALEAAHQAGTVQRFLEFS 124

Query: 312 STCIFPDKTTYPIDE-TMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCN 488
           ++ +F  +  Y +DE      G    + + Y+ +K   + L   YN  +G    +  P N
Sbjct: 125 TSEVFGSRA-YRVDELNSTTTGAVGEARWTYAVSKLAGEHLTHAYNREHGLPTVTFRPFN 183

Query: 489 VFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAV 656
           V+GP           I  +IR+   A+   D    + G G  +R + Y  D+  A+
Sbjct: 184 VYGP----GQIGEGAISIMIRK---ALNNED--IYIFGDGSQIRAWCYVDDMIDAL 230


>UniRef50_Q58M85 Cluster: Nucleotide-sugar epimerase; n=1;
           Cyanophage P-SSM2|Rep: Nucleotide-sugar epimerase -
           Cyanophage P-SSM2
          Length = 301

 Score = 37.9 bits (84), Expect = 0.25
 Identities = 52/205 (25%), Positives = 84/205 (40%), Gaps = 1/205 (0%)
 Frame = +3

Query: 57  RNSDYDSETWIFSG-SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFF 233
           +++D D   W     + D D+ D    + +F  +K  +V HLAA    +   + + +   
Sbjct: 36  KSADNDKFHWNDKAWNVDCDITDYKAMKNVF--NKVDYVFHLAAE-SRIQSAIDNPIQAV 92

Query: 234 RENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAK 413
           + N      +LQ   +  VK+ V   ST        +P  ET      P      YS  K
Sbjct: 93  QRNCVGTATVLQCAREAGVKRFVYS-STSSGYGNNPFPNVETQ-----PDDCLNPYSATK 146

Query: 414 RMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFT 593
              + L + Y   YG     +   NVFG       + + VI    R++D      +P  T
Sbjct: 147 VAGEKLCKMYTNLYGLETVVLRYFNVFGQRSPTKGQYAPVIGIFRRQLDSK----EP-LT 201

Query: 594 VMGSGKPLRQFIYSLDLARAVHLGS 668
           ++G G   R F++  D+ARA +L S
Sbjct: 202 IVGDGSQRRDFVHVNDVARANYLAS 226


>UniRef50_Q8PXQ4 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=3;
           Methanomicrobia|Rep: UDP-N-acetylglucosamine 4-epimerase
           - Methanosarcina mazei (Methanosarcina frisia)
          Length = 334

 Score = 37.9 bits (84), Expect = 0.25
 Identities = 37/132 (28%), Positives = 54/132 (40%)
 Frame = +3

Query: 258 NILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNR 437
           N+L+A     VKKV++  S+ ++      P DE   H   P S    Y  +K   +   R
Sbjct: 109 NVLKASLDAGVKKVINASSSSVYGKVKYLPFDEQ--HPTEPVSP---YGVSKLAAEHYCR 163

Query: 438 GYNESYGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPL 617
            + E YG   TS+    V+GP     +     I    R+M       +   TV G G+  
Sbjct: 164 VFYEVYGLPTTSLRYFTVYGP----RMRPDLAISIFTRKM-----LANEPITVFGDGEQT 214

Query: 618 RQFIYSLDLARA 653
           R F Y  D+  A
Sbjct: 215 RDFTYIEDVVEA 226


>UniRef50_O26473 Cluster: DTDP-glucose 4,6-dehydratase related
           protein; n=2; Methanobacteriaceae|Rep: DTDP-glucose
           4,6-dehydratase related protein - Methanobacterium
           thermoautotrophicum
          Length = 334

 Score = 37.9 bits (84), Expect = 0.25
 Identities = 32/138 (23%), Positives = 65/138 (47%), Gaps = 3/138 (2%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           D+R+  Q E +F + K  +V HLAA   G ++   +  + ++ N+    ++L+   K   
Sbjct: 68  DVREYRQVERIFEEDKFDYVYHLAAEY-GRWNGEDYYENLWKTNVIGTKHMLRMQEKLGF 126

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNF---GYSYAKRMIDVLNRGYNESYGC 461
            +++   S  ++ D +    ++ MV N  P S  +    Y+  K   +++     E +G 
Sbjct: 127 -RMIFFSSAEVYGDYSGLMSEDVMVKN--PISDTYQMNDYAITKWAGELMCMNSAEMFGT 183

Query: 462 MFTSVIPCNVFGPYDNFS 515
               V P N +GP++ +S
Sbjct: 184 ETVRVRPVNCYGPHEKYS 201


>UniRef50_Q4K1T9 Cluster: Putative dehydratase/epimerase
           (Arabinitol) Abp2; n=6; Streptococcus pneumoniae|Rep:
           Putative dehydratase/epimerase (Arabinitol) Abp2 -
           Streptococcus pneumoniae
          Length = 362

 Score = 37.5 bits (83), Expect = 0.33
 Identities = 40/167 (23%), Positives = 74/167 (44%), Gaps = 3/167 (1%)
 Frame = +3

Query: 165 HVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIF---PDK 335
           ++IH A+      + +++ +D    N     N+L    K +V  +V   S+ ++    + 
Sbjct: 103 YIIHGASNASPDLY-ISNPVDTMLSNFLGMKNLLDYALKKSVSSIVYVSSSEVYGKTENH 161

Query: 336 TTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFS 515
           T Y  DE    N     ++  YS +KR  + L + Y+E Y      V P +++GP  +  
Sbjct: 162 TPYQEDEYGYVNILDVRAS--YSSSKRATETLCKSYSEQYDVSIKIVRPGHIYGP--SLK 217

Query: 516 LESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAV 656
           +    +  A    M DA++       +   G+ LR + +SLD A A+
Sbjct: 218 ITDKRISSAF---MYDAIR--GQNLVMKSKGEQLRSYCHSLDCASAI 259


>UniRef50_A7HBK8 Cluster: NAD-dependent epimerase/dehydratase; n=4;
           Bacteria|Rep: NAD-dependent epimerase/dehydratase -
           Anaeromyxobacter sp. Fw109-5
          Length = 312

 Score = 37.5 bits (83), Expect = 0.33
 Identities = 47/183 (25%), Positives = 77/183 (42%), Gaps = 2/183 (1%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQ-ACHKYN 287
           D+R     E L  K +P  + H AA +  +  +MA        N+    N++Q A    +
Sbjct: 53  DVRSAAALEVL-KKERPQVICHQAAQID-VRRSMAEPRFDADVNVGGLLNLMQGAVEAKS 110

Query: 288 VKKVVSCLST-CIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
           V+ V+   S    + D    P  E   H   P S    Y  AK   ++    Y  +YG  
Sbjct: 111 VEHVLFASSGGATYGDTDRVPTPED--HPQLPVSH---YGAAKAASELYLNVYRANYGIP 165

Query: 465 FTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDL 644
           FT++   NV+GP      +  H    ++      + +G P  T+ G G   R ++++ D+
Sbjct: 166 FTALRYSNVYGP-----RQDPHGEAGVVAIFCGRLLEGRPC-TIFGDGSQTRDYVFAGDV 219

Query: 645 ARA 653
           ARA
Sbjct: 220 ARA 222


>UniRef50_A4BBD6 Cluster: Putative uncharacterized protein; n=1;
           Reinekea sp. MED297|Rep: Putative uncharacterized
           protein - Reinekea sp. MED297
          Length = 314

 Score = 37.5 bits (83), Expect = 0.33
 Identities = 34/154 (22%), Positives = 70/154 (45%), Gaps = 3/154 (1%)
 Frame = +3

Query: 3   SGLVGQAIKTVIERDRQKRNSDYDSETWIFSGSKDGDLRDKTQTEALFAKHKPTHVIHLA 182
           +G +G  +   + ++ Q    D  + +      K  D+ D+T  + L  +H+ THV+HLA
Sbjct: 13  AGYIGHQVGNALAKEHQVLGCDIRACSAAQFEIKHLDINDETLAD-LMREHRITHVVHLA 71

Query: 183 AMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYPIDET- 359
           +++     + A +   +R ++    N+++AC    V+ +    S   +     Y  D   
Sbjct: 72  SVLEA-SEDRARD---YRIDVDGTRNVIEACLAAGVEHLTVSSSGAAY----GYHADNAE 123

Query: 360 MVHNGPPHSSN--FGYSYAKRMIDVLNRGYNESY 455
            +    P   N  F YS+ KR+++ +   Y +S+
Sbjct: 124 WLSEADPLRGNYEFAYSWHKRLVEDMLAEYRQSH 157


>UniRef50_Q96VM0 Cluster: Putative dTDP-glucose 4,6-dehydratase;
           n=1; Yarrowia lipolytica|Rep: Putative dTDP-glucose
           4,6-dehydratase - Yarrowia lipolytica (Candida
           lipolytica)
          Length = 327

 Score = 37.5 bits (83), Expect = 0.33
 Identities = 36/126 (28%), Positives = 57/126 (45%)
 Frame = +3

Query: 285 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
           N+ K++   +  I+ D+      E +    P   SN  Y+ +K   ++    Y +SYG  
Sbjct: 121 NLPKLIYISTDEIYGDQADLTGTEDL-ETSPLCPSN-PYAASKAAAEMFISAYTKSYGLE 178

Query: 465 FTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDL 644
             ++   NV+G Y         +IPA       AM KGD    + GSG+  R++IY+ D 
Sbjct: 179 CVTLRFNNVYGEYQY----PEKIIPAFCL----AMLKGDKCM-LQGSGEHRRRYIYADDC 229

Query: 645 ARAVHL 662
             AV L
Sbjct: 230 VNAVQL 235


>UniRef50_A3H6D1 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Caldivirga maquilingensis IC-167|Rep: NAD-dependent
           epimerase/dehydratase - Caldivirga maquilingensis IC-167
          Length = 326

 Score = 37.5 bits (83), Expect = 0.33
 Identities = 41/189 (21%), Positives = 80/189 (42%), Gaps = 3/189 (1%)
 Frame = +3

Query: 105 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 284
           + DL D  +  ++  +     +IHLAAM+  L  +    L   + N+    N+ +A    
Sbjct: 52  NADLSDFDELISIIKRFNVRRIIHLAAMI--LLESRNRPLKAAKVNIIGTLNVFEAARLM 109

Query: 285 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
           ++++VV   S  ++     Y    ++  +  PH+    Y   K   ++    Y+E+YG  
Sbjct: 110 DLERVVYASSESVYGSPLVYG-KGSVNEDDYPHTPPDPYHITKLADELFGSYYSEAYGLS 168

Query: 465 FTSVIPCNVFGP--YDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSL 638
                    +GP  Y  ++ + +  +  +I +      K  P F   G+     +++Y  
Sbjct: 169 VIGGRLTTAWGPGRYSGYTGQFNSFLRDVIIK---GYGKVPPDFAYSGA---KYRWLYVK 222

Query: 639 DLARA-VHL 662
           D ARA +HL
Sbjct: 223 DAARAFIHL 231


>UniRef50_O95455 Cluster: dTDP-D-glucose 4,6-dehydratase; n=24;
           Eumetazoa|Rep: dTDP-D-glucose 4,6-dehydratase - Homo
           sapiens (Human)
          Length = 350

 Score = 37.5 bits (83), Expect = 0.33
 Identities = 41/182 (22%), Positives = 72/182 (39%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           GD+ D    + LF   K   V+H AA    +  +     +F   N+     ++ A H+  
Sbjct: 75  GDICDSHFVKLLFETEKIDIVLHFAAQTH-VDLSFVRAFEFTYVNVYGTHVLVSAAHEAR 133

Query: 288 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 467
           V+K +   +  ++        DE+     P   +N  Y+ +K   +   + Y E Y    
Sbjct: 134 VEKFIYVSTDEVYGGSLDKEFDES----SPKQPTN-PYASSKAAAECFVQSYWEQYKFPV 188

Query: 468 TSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLA 647
                 NV+GP+         VIP  I     ++ + +    + GSG   R F+Y+ D+ 
Sbjct: 189 VITRSSNVYGPHQY----PEKVIPKFI-----SLLQHNRKCCIHGSGLQTRNFLYATDVV 239

Query: 648 RA 653
            A
Sbjct: 240 EA 241


>UniRef50_Q814Z6 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=1;
           Bacillus cereus ATCC 14579|Rep: UDP-N-acetylglucosamine
           4-epimerase - Bacillus cereus (strain ATCC 14579 / DSM
           31)
          Length = 301

 Score = 37.1 bits (82), Expect = 0.43
 Identities = 35/163 (21%), Positives = 73/163 (44%)
 Frame = +3

Query: 168 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 347
           V+HLAA  G         +  F +N  +  N+  AC++ N+  +V   +   + D+T+ P
Sbjct: 64  VVHLAATRGS-----QGKISEFHDNEILTQNLYDACYENNISNIVYASTISAYSDETSLP 118

Query: 348 IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESS 527
            +E  +   P     +G S  K   + +   Y+   G    ++   +++G    F+ +++
Sbjct: 119 WNEKEL---PLPDLMYGVS--KLACEHIGNIYSRKKGLCIKNLRFAHLYG----FNEKNN 169

Query: 528 HVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAV 656
           ++I    R+     Q      T+  +    R+F+Y+ D A++V
Sbjct: 170 YMINRFFRQAFHGEQ-----LTLHANSVAKREFLYAKDAAKSV 207


>UniRef50_Q2JCE7 Cluster: DTDP-glucose 4,6-dehydratase; n=5;
           Bacteria|Rep: DTDP-glucose 4,6-dehydratase - Frankia sp.
           (strain CcI3)
          Length = 357

 Score = 37.1 bits (82), Expect = 0.43
 Identities = 45/184 (24%), Positives = 76/184 (41%), Gaps = 1/184 (0%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           GD+RD+   E++  +H    V++ AA        +    +FF  N+     +L+A     
Sbjct: 80  GDIRDQELVESVLREHSVDVVVNFAAESHNSLAIIRPG-EFFATNVMGTQTLLEAARTVG 138

Query: 288 VKKVVSCLSTC-IFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
           V +    +STC ++ D      D        P+     Y+ AK   D   R Y  +Y   
Sbjct: 139 VARFHQ-ISTCEVYGDMDLN--DPGAFTEDSPYLPRTPYNAAKAGGDHAVRAYGFTYNLP 195

Query: 465 FTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDL 644
            T     N +GPY         VIP  + R   A+Q G+ +  +  S    R++++ +D 
Sbjct: 196 VTITNCSNNYGPYQ----FPEKVIPLFVTR---ALQ-GE-SLPMYASTTNRREWLHVMDH 246

Query: 645 ARAV 656
            RA+
Sbjct: 247 CRAI 250


>UniRef50_A6Q4T4 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Nitratiruptor sp. SB155-2|Rep: NAD-dependent
           epimerase/dehydratase - Nitratiruptor sp. (strain
           SB155-2)
          Length = 294

 Score = 37.1 bits (82), Expect = 0.43
 Identities = 38/162 (23%), Positives = 68/162 (41%), Gaps = 5/162 (3%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQAC--HKY 284
           D+  K Q   +F K    ++IHLAA+    F   A  +  +  N     N+L A    ++
Sbjct: 44  DITKKEQIRQIFQKKSFDYIIHLAAI---SFVGYADQVKMYEVNAFGVQNLLSALEEQEW 100

Query: 285 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
             KKV+   S  ++  + T  + E +  N   H     Y+Y+K + + + + Y +    +
Sbjct: 101 TAKKVIITSSATVYGMQRTNKLHEKLCPNPNNH-----YAYSKYISEQIAKTYFDKIPII 155

Query: 465 FTSVIPCNVFGPYDNFSLESSHVIPALIR---RMDDAMQKGD 581
            T   P N    Y         ++P L+R   R D  ++ G+
Sbjct: 156 ITR--PFN----YTGCGQREEFIVPKLVRAFQRKDSIIEIGN 191


>UniRef50_A4QBQ0 Cluster: Putative uncharacterized protein; n=1;
           Corynebacterium glutamicum R|Rep: Putative
           uncharacterized protein - Corynebacterium glutamicum
           (strain R)
          Length = 335

 Score = 37.1 bits (82), Expect = 0.43
 Identities = 20/83 (24%), Positives = 41/83 (49%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           GD+RD+   +++ A+++P+  IH AA    +  ++     +   N+     +L A H   
Sbjct: 62  GDIRDRAFVDSVLAQYQPSAAIHFAAK-KAVGESVEQPTMYLNINIGGTATLLDALHHAG 120

Query: 288 VKKVVSCLSTCIFPDKTTYPIDE 356
           V+ +V   S  +  + T  P++E
Sbjct: 121 VRDIVFSSSCSVHGETTHSPLNE 143


>UniRef50_P55295 Cluster: dTDP-glucose 4,6-dehydratase; n=185;
           Bacteria|Rep: dTDP-glucose 4,6-dehydratase - Xanthomonas
           campestris pv. campestris
          Length = 351

 Score = 37.1 bits (82), Expect = 0.43
 Identities = 45/188 (23%), Positives = 79/188 (42%), Gaps = 5/188 (2%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           GD+ D      L  +H+P  V++ AA    +  ++     F + N+     +L+A   Y 
Sbjct: 57  GDIGDGALVTRLLQEHQPDAVLNFAAE-SHVDRSIEGPGAFIQTNVVGTLALLEAVRDYW 115

Query: 288 VKKVVSCLSTCIFPDKTTYPIDETMVHNGP-----PHSSNFGYSYAKRMIDVLNRGYNES 452
                +      F   +T  +  T+   G      P++ N  YS +K   D L R ++ +
Sbjct: 116 KALPDTRRDAFRFLHVSTDEVYGTLGETGKFTETTPYAPNSPYSASKAASDHLVRAFHHT 175

Query: 453 YGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIY 632
           YG    +    N +GPY +F      +IP +I +       G+P   V G GK +R +++
Sbjct: 176 YGLPVLTTNCSNNYGPY-HF---PEKLIPLVIAK----ALAGEP-LPVYGDGKQVRDWLF 226

Query: 633 SLDLARAV 656
             D   A+
Sbjct: 227 VSDHCEAI 234


>UniRef50_Q59083 Cluster: UDP-glucose 4-epimerase; n=14;
           Bacteria|Rep: UDP-glucose 4-epimerase - Azospirillum
           brasilense
          Length = 348

 Score = 37.1 bits (82), Expect = 0.43
 Identities = 46/208 (22%), Positives = 88/208 (42%), Gaps = 12/208 (5%)
 Frame = +3

Query: 105 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 284
           +GD+      + +   H+   V+H A  +  +  ++   LD++R N + +  +L AC + 
Sbjct: 57  EGDIGSAELLDRVMRDHRVDAVMHFAGSIV-VPESVVKPLDYYRNNTANSLTLLGACLRA 115

Query: 285 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
            + KVV   +  ++    + PI E    + P    N  Y  +K M + + R    ++G  
Sbjct: 116 GIDKVVFSSTAAVYGAPESVPIRE----DAPTVPIN-PYGASKLMTEQMLRDAGAAHGLR 170

Query: 465 FTSVIPCNVFGPYD-NFSLESSHVIPALIRRMDDAMQKGDPTFTVMGS------GKPLRQ 623
              +   NV G      + +++ V   LI+    A+    P   + G+      G  +R 
Sbjct: 171 SVILRYFNVAGADPAGRTGQATPVATHLIKVACQALLGRRPPLAIFGTDYDTPDGTCIRD 230

Query: 624 FIYSLDLARA-----VHLGSSGTTTVSN 692
           +I+  DLA A     +HL   G + + N
Sbjct: 231 YIHVSDLADAHVLALLHLRRGGGSLLMN 258


>UniRef50_Q7CS52 Cluster: AGR_L_3011p; n=3; Alphaproteobacteria|Rep:
           AGR_L_3011p - Agrobacterium tumefaciens (strain C58 /
           ATCC 33970)
          Length = 356

 Score = 36.7 bits (81), Expect = 0.57
 Identities = 48/195 (24%), Positives = 77/195 (39%), Gaps = 7/195 (3%)
 Frame = +3

Query: 105 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 284
           +GD+ D    +A   +  P  VIH AA    +  ++     ++R N+  + ++L AC   
Sbjct: 79  EGDILDGVLLKATLREFSPAFVIHCAAN-AYVGESVEDPRKYYRNNVGGSLSLLDACLDQ 137

Query: 285 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
           N+  +V   S   +      PI E      P +     Y   K + ++    Y  +YG  
Sbjct: 138 NIGGLVFSSSCATYGVPQQLPIREETAQM-PVNP----YGRTKLIFEMALEDYAAAYGLR 192

Query: 465 FTSVIPCNVFGPYDNFSLESSHVIPA-LIRRMDDAMQKGDPTFTVMGS------GKPLRQ 623
           F ++   N  G   +  L   H     LI R   A     P   V G+      G  +R 
Sbjct: 193 FVALRYFNAAGADPDGELYERHEPETHLIPRALMAAAARLPQLDVFGADYDTSDGTCIRD 252

Query: 624 FIYSLDLARAVHLGS 668
           +I+  DLA A HL +
Sbjct: 253 YIHVSDLADA-HLAA 266


>UniRef50_Q2FA40 Cluster: DTDP-glucose 4-6-dehydratase; n=4;
           Bacteria|Rep: DTDP-glucose 4-6-dehydratase - Vibrio sp.
           DAT722
          Length = 357

 Score = 36.7 bits (81), Expect = 0.57
 Identities = 38/166 (22%), Positives = 65/166 (39%), Gaps = 1/166 (0%)
 Frame = +3

Query: 168 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 347
           VIH AA     +H     +   + N+    N+L+     +V   +   +  ++ +     
Sbjct: 115 VIH-AASSASPYHIKNDPVGIIKANVQGTSNLLELVKDMHVSNFLFLSTREVYGEVLDVE 173

Query: 348 -IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLES 524
            I+ET   +  P  +   Y  +KR+ + + + Y   YG  F SV   + +GP     L  
Sbjct: 174 YIEETDFGHFDPLDARSCYPESKRLAETMLQSYAVQYGLTFNSVRIAHSYGP--GMFLND 231

Query: 525 SHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAVHL 662
             V+  L   + D +   D    +   G  LR F Y  D   A+ L
Sbjct: 232 GRVMSDL---LGDVV--NDKPIVLKSDGSALRSFCYVTDAVSALLL 272


>UniRef50_A6FPS1 Cluster: NAD-dependent epimerase/dehydratase; n=5;
           Rhodobacterales|Rep: NAD-dependent epimerase/dehydratase
           - Roseobacter sp. AzwK-3b
          Length = 337

 Score = 36.7 bits (81), Expect = 0.57
 Identities = 38/183 (20%), Positives = 73/183 (39%)
 Frame = +3

Query: 114 LRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVK 293
           L DK   +    +  P  ++HLAA   G+ +++ +   +   N+    N++ A  ++ V+
Sbjct: 63  LEDKNAVDRAIDEFAPDVIVHLAAQ-AGVRYSLENPRAYLDANVIGTFNVMDAAKRHEVE 121

Query: 294 KVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTS 473
            ++   ++ ++   T  P  ET        +    Y+  K+  + +   Y   Y    T 
Sbjct: 122 HLLMASTSSVYGANTEMPFVET----EKADTQLTIYAATKKANESMAHAYAHLYDLPTTM 177

Query: 474 VIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARA 653
                V+GP+    L       AL + +D  ++ G P   +   G   R F Y  DL   
Sbjct: 178 FRFFTVYGPWGRPDL-------ALFKFVDTILE-GRP-IDIYNHGDMYRDFTYVDDLVHG 228

Query: 654 VHL 662
           + L
Sbjct: 229 IRL 231


>UniRef50_A6SIX9 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 348

 Score = 36.7 bits (81), Expect = 0.57
 Identities = 25/79 (31%), Positives = 36/79 (45%)
 Frame = +3

Query: 105 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 284
           DGD+       ++F   KP  VIH A+ V         N  F++ N+     +++AC K 
Sbjct: 58  DGDITSLESLLSIFNSIKPDVVIHTASPVA----ITGTNDLFYKVNVGGTKCVVEACQKT 113

Query: 285 NVKKVVSCLSTCIFPDKTT 341
            VK +V   S  I  D TT
Sbjct: 114 GVKALVFTSSASIISDNTT 132


>UniRef50_O26480 Cluster: UDP-glucose 4-epimerase homolog; n=3;
           cellular organisms|Rep: UDP-glucose 4-epimerase homolog
           - Methanobacterium thermoautotrophicum
          Length = 316

 Score = 36.7 bits (81), Expect = 0.57
 Identities = 46/178 (25%), Positives = 78/178 (43%), Gaps = 1/178 (0%)
 Frame = +3

Query: 165 HVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTY 344
           +V H AA+   +  ++   L   R N +    +L A  +  V+KVV+  ++ ++ +    
Sbjct: 73  YVFHQAALAS-VPESVRDPLRCHRVNATGTLRVLMASSRAGVRKVVNASTSAVYGNNPEI 131

Query: 345 PIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLES 524
           P+ E       P S    Y+ +K   +   + + E  G    S+   NV+GP      + 
Sbjct: 132 PLREDA--RPMPLSP---YAVSKVTGEYYCQVF-EDQGLETVSLRYFNVYGPRQRPDSQY 185

Query: 525 SHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARA-VHLGSSGTTTVSNL 695
           + VIP  I    DA+  G     + G G+  R FIY  D+ RA + L  S  + V N+
Sbjct: 186 AAVIPRFI----DALLSGRSP-EIYGDGEQSRDFIYVGDVVRANIFLAESRGSGVYNV 238


>UniRef50_P14169 Cluster: CDP-paratose 2-epimerase; n=12; cellular
           organisms|Rep: CDP-paratose 2-epimerase - Salmonella
           typhi
          Length = 338

 Score = 36.7 bits (81), Expect = 0.57
 Identities = 45/216 (20%), Positives = 85/216 (39%), Gaps = 16/216 (7%)
 Frame = +3

Query: 45  DRQKRNSDYDSETWIFS-GSKD---GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNM 212
           D   R    D+  W+ S G+ +   GD+R+K     L  K+ P    HLA  V  +  ++
Sbjct: 31  DNLSRKGATDNLHWLSSLGNFEFVHGDIRNKNDVTRLITKYMPDSCFHLAGQV-AMTTSI 89

Query: 213 AHNLDFFRENMSINDNILQACHKYNVK-KVVSCLSTCIFPDKTTYPIDETMVH------- 368
            +    F  N+    N+L+A  +YN    ++   +  ++ D   Y  +ET          
Sbjct: 90  DNPCMDFEINVGGTLNLLEAVRQYNSNCNIIYSSTNKVYGDLEQYKYNETETRYTCVDKP 149

Query: 369 NGPPHSSNFG----YSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESSHVI 536
           NG   S+       Y  +K   D     Y   +G         +++G    F+      +
Sbjct: 150 NGYDESTQLDFHSPYGCSKGAADQYMLDYARIFGLNTVVFRHSSMYGG-RQFATYDQGWV 208

Query: 537 PALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDL 644
               ++  +     +  FT+ G+GK +R  +++ D+
Sbjct: 209 GWFCQKAVEIKNGINKPFTISGNGKQVRDVLHAEDM 244


>UniRef50_Q4AGU6 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           Bacteria|Rep: NAD-dependent epimerase/dehydratase -
           Chlorobium phaeobacteroides BS1
          Length = 304

 Score = 36.3 bits (80), Expect = 0.76
 Identities = 33/134 (24%), Positives = 56/134 (41%), Gaps = 1/134 (0%)
 Frame = +3

Query: 261 ILQACHKYNVKKVVSCLSTCIFPDKTTYPID-ETMVHNGPPHSSNFGYSYAKRMIDVLNR 437
           +L+ C    ++KVV   S       T Y I  E  VH   P +    Y   K +I+    
Sbjct: 97  LLEQCVAKKIRKVVFISS-----GGTVYGIPTEIPVHENNPTNPECSYGITKLVIEKYLA 151

Query: 438 GYNESYGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPL 617
            +   YG  +  V P N +G   N +      IP  + +    + KG+ +  + G G+ +
Sbjct: 152 LFKHLYGLNYVIVRPSNPYGERQNPN-SIQGAIPVFLNK----VAKGE-SIDIWGDGEVV 205

Query: 618 RQFIYSLDLARAVH 659
           R +I+  DL   ++
Sbjct: 206 RDYIFIDDLVDGIY 219


>UniRef50_A3Q712 Cluster: UDP-glucose 4-epimerase; n=6;
           Actinobacteria (class)|Rep: UDP-glucose 4-epimerase -
           Mycobacterium sp. (strain JLS)
          Length = 329

 Score = 36.3 bits (80), Expect = 0.76
 Identities = 35/131 (26%), Positives = 53/131 (40%), Gaps = 1/131 (0%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAM-VGGLFHNMAHNLDFFRENMSINDNILQACHKY 284
           G L D    E    +H+ T VIH+A     G+  ++   L  + +N+S    +LQA    
Sbjct: 50  GTLLDGALVEQALREHEVTGVIHIAGFKYAGV--SVQRPLHTYEQNVSAMVTLLQAMETV 107

Query: 285 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
            V K+V   S   F       +DE+      P +    Y   K + + L R    + G  
Sbjct: 108 GVDKIVFSSSAATFGTPDVDQVDES-----TPTAPESPYGETKLIGEWLLRDAGRASGLR 162

Query: 465 FTSVIPCNVFG 497
            TS+   NV G
Sbjct: 163 HTSLRYFNVVG 173


>UniRef50_Q4CYB9 Cluster: GDP-mannose 4,6 dehydratase, putative;
           n=3; root|Rep: GDP-mannose 4,6 dehydratase, putative -
           Trypanosoma cruzi
          Length = 378

 Score = 36.3 bits (80), Expect = 0.76
 Identities = 39/168 (23%), Positives = 75/168 (44%), Gaps = 1/168 (0%)
 Frame = +3

Query: 153 HKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN-VKKVVSCLSTCIFP 329
           H    +I+ AA    + ++  ++L F   N+     +L+    Y  ++K +  +ST    
Sbjct: 93  HDIDTIINFAAQ-SHVDNSFGNSLSFTYNNVLGTHVLLECARTYGRIEKFIH-VST---- 146

Query: 330 DKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDN 509
           D+    + ++    G  + +N  Y+  K  ++ + + Y+ S+G         NV+GPY  
Sbjct: 147 DEVYGQVTDSKKEEGTLNPTN-PYAATKAAVEYIVKSYHISFGLPCIITRGNNVYGPYQY 205

Query: 510 FSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARA 653
                  +IP  I  M+   +      T+ G+G   R FI++ D+ARA
Sbjct: 206 ----PEKLIPRFIMLMNAGKK-----LTIQGNGSNKRTFIHASDVARA 244


>UniRef50_A2R6J0 Cluster: Catalytic activity: dTDPglucose =
           dTDP-4-dehydro-6-deoxy-D-glucose + H2O; n=1; Aspergillus
           niger|Rep: Catalytic activity: dTDPglucose =
           dTDP-4-dehydro-6-deoxy-D-glucose + H2O - Aspergillus
           niger
          Length = 362

 Score = 36.3 bits (80), Expect = 0.76
 Identities = 43/182 (23%), Positives = 72/182 (39%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           GDL D+ +  ALF + K   V+H AA    +  ++ + L F R N++    +L+A  +  
Sbjct: 81  GDLCDRDRVTALFQQFKVDAVVHFAAN-SHVDQSLVNPLSFTRSNVTGTHVLLEAARQAG 139

Query: 288 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 467
                  +ST           D         + +N  YS +K   +++   Y  S+    
Sbjct: 140 TVIRFIHISTDEVYGGNMPGQDYAFTEEDQLNPTN-PYSASKAAAEMIANSYRYSFHMPI 198

Query: 468 TSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLA 647
                 NVFGP          +IP    +M  + +      T+ G G+ +R F+Y  D  
Sbjct: 199 IITRCNNVFGPCQ----YPEKLIPKFAMQMLRSQR-----MTLHGQGEAVRGFVYVSDAM 249

Query: 648 RA 653
            A
Sbjct: 250 SA 251


>UniRef50_A1CX38 Cluster: Dtdp-glucose 4,6-dehydratase; n=6;
           Pezizomycotina|Rep: Dtdp-glucose 4,6-dehydratase -
           Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL
           181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
           3700 / NRRL 181))
          Length = 411

 Score = 36.3 bits (80), Expect = 0.76
 Identities = 45/197 (22%), Positives = 82/197 (41%), Gaps = 8/197 (4%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           GD+            HK   VIH AA    +  +  ++  F R+N+   + +L++  +  
Sbjct: 99  GDVTSADDVMRCLHAHKIDVVIHFAAQ-SHVDLSFRNSYSFIRDNIYGTNVLLESVRQSG 157

Query: 288 VKKVVSCLSTCIF----PDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESY 455
           +++ +   +  ++     D    P D  +    P       YS +K   +++   Y++S+
Sbjct: 158 IRRFIHVSTDEVYGEVPDDGEDLPEDSILAPTNP-------YSASKAAAEMMILAYSKSF 210

Query: 456 GCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYS 635
                 V   NV+GP+         VIP  I      +Q+G    TV G G   R+++++
Sbjct: 211 RLPAIVVRLNNVYGPHQ----FPEKVIPKFI----SLLQRGQ-KLTVYGDGTNSRRYLWA 261

Query: 636 LDLARA----VHLGSSG 674
            D A A    +H GS G
Sbjct: 262 GDAADAFDTILHKGSVG 278


>UniRef50_Q7UXZ2 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=2;
           Planctomycetaceae|Rep: 3-beta-hydroxysteroid
           dehydrogenase - Rhodopirellula baltica
          Length = 339

 Score = 35.9 bits (79), Expect = 1.00
 Identities = 33/130 (25%), Positives = 60/130 (46%), Gaps = 1/130 (0%)
 Frame = +3

Query: 168 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCI-FPDKTTY 344
           VIH AA V G++ +  H   +F  N+  + N+LQAC +  V +++   S  + F      
Sbjct: 67  VIHTAA-VAGVWGSWQH---YFDNNVVASRNVLQACQELGVSQLIYTSSPSVTFDGNDQR 122

Query: 345 PIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLES 524
            +DE   +   P +    Y + K + +      ++  G    S+ P  ++GP D      
Sbjct: 123 DVDEAEPY---PETWMCHYPHTKSIAEREILAADQPGGMRTVSLRPHLIWGPDD------ 173

Query: 525 SHVIPALIRR 554
            H+IP +++R
Sbjct: 174 PHLIPRVLQR 183


>UniRef50_Q8U170 Cluster: UDP-or dTTP-glucose 4-epimerase or
           4-6-dehydratase; n=5; Euryarchaeota|Rep: UDP-or
           dTTP-glucose 4-epimerase or 4-6-dehydratase - Pyrococcus
           furiosus
          Length = 336

 Score = 35.9 bits (79), Expect = 1.00
 Identities = 41/175 (23%), Positives = 64/175 (36%)
 Frame = +3

Query: 132 TEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCL 311
           ++ L  + K   + H A+     F    + L+    N     N+L+   K N + + +  
Sbjct: 81  SKPLEIREKLDFIFHFASRASP-FEFEHYPLEIIDANTLGTRNMLELAKKNNARFIFAST 139

Query: 312 STCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNV 491
           S  I+      P  ET      P      Y  +KR+ + L   Y   +      V   N 
Sbjct: 140 SE-IYGHPEVVPTPETYWGYVNPIGIRSCYDESKRLGEALTMAYYRQFNVDVRIVRIFNT 198

Query: 492 FGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAV 656
           +GP          V+P  I +   A+ + +P  TV G G   R F Y  DL   V
Sbjct: 199 YGPRMRADGVYGRVVPRFISQ---ALNE-EP-ITVFGDGSQTRSFCYVTDLITGV 248


>UniRef50_Q2NFA4 Cluster: Predicted dTDP-4-dehydrorhamnose
           reductase; n=1; Methanosphaera stadtmanae DSM 3091|Rep:
           Predicted dTDP-4-dehydrorhamnose reductase -
           Methanosphaera stadtmanae (strain DSM 3091)
          Length = 286

 Score = 35.9 bits (79), Expect = 1.00
 Identities = 30/119 (25%), Positives = 48/119 (40%), Gaps = 1/119 (0%)
 Frame = +3

Query: 3   SGLVGQAIKTVIERDRQKRNSDYDSETWIFSGSKDGDLRDKTQTEALFAKHKPTHVIHLA 182
           SGL+G+ + T+   D +   S   + T     +   D+ DK + E +  K+KP  ++H A
Sbjct: 9   SGLLGERLATIASNDDEIVLSHNSNPT---KNTIKCDITDKNEVEKVINKNKPDTIVHCA 65

Query: 183 AMVGGLFHNMAHNLDF-FRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYPIDE 356
           AM           +D  +R N     N+ QA      K +          DK  Y  D+
Sbjct: 66  AMTD--VDLCEDEIDIAYRINSDGTRNMAQAAENIGAKIIYVSTDFVFDGDKGYYSEDD 122


>UniRef50_Q4FRJ1 Cluster: LPS-assembly protein precursor; n=2;
           Psychrobacter|Rep: LPS-assembly protein precursor -
           Psychrobacter arcticum
          Length = 912

 Score = 35.9 bits (79), Expect = 1.00
 Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 2/135 (1%)
 Frame = +3

Query: 126 TQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFREN-MSINDNILQACHKYNVKKVV 302
           TQT+    K+  T +   AA  GGL   +A NL++  E   S   N+  A  +       
Sbjct: 225 TQTQDRVQKNGKTSLTDKAAQ-GGLI-GVADNLNYNTETGQSTATNVAFASVELQAHGYA 282

Query: 303 SCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDV-LNRGYNESYGCMFTSVI 479
             L+    P+++ Y +DE M    PP  +N  + +  + ID+    G  E+Y   F    
Sbjct: 283 KRLNR---PNESQYELDEVMYSTCPP--TNRKWQFDAKSIDLDTETGRGEAYNTTFRIAD 337

Query: 480 PCNVFGPYDNFSLES 524
               + PY NF ++S
Sbjct: 338 VPVFYLPYFNFPIDS 352


>UniRef50_UPI0001597850 Cluster: hypothetical protein RBAM_031220;
           n=1; Bacillus amyloliquefaciens FZB42|Rep: hypothetical
           protein RBAM_031220 - Bacillus amyloliquefaciens FZB42
          Length = 309

 Score = 35.5 bits (78), Expect = 1.3
 Identities = 19/64 (29%), Positives = 32/64 (50%)
 Frame = +3

Query: 168 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 347
           V+HLAAMV G+    ++  D  R N     N+ + C +  +  ++   S+ +F D   +P
Sbjct: 63  VVHLAAMV-GVDSCRSNEEDVIRVNFEGTKNVTEVCGELGISTLLFSSSSEVFGDSPDFP 121

Query: 348 IDET 359
             ET
Sbjct: 122 YTET 125


>UniRef50_Q97L35 Cluster: FUSION: Nucleoside-diphosphate-sugar
           epimerase and GAF domain; n=1; Clostridium
           acetobutylicum|Rep: FUSION: Nucleoside-diphosphate-sugar
           epimerase and GAF domain - Clostridium acetobutylicum
          Length = 725

 Score = 35.5 bits (78), Expect = 1.3
 Identities = 36/147 (24%), Positives = 63/147 (42%), Gaps = 1/147 (0%)
 Frame = +3

Query: 258 NILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNR 437
           N+L    KY VK+ +   S  ++ +      +E  ++   P++ N      K + +   +
Sbjct: 97  NLLNFSSKYGVKRFIFASSASVYGNNNLTIKEEAEINPLSPYAVN------KYVGEFYTQ 150

Query: 438 GYNESYGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPL 617
            + E YG    S+   NVFGP  +   E  +V+   I +   A++  +      G G   
Sbjct: 151 KWFEIYGLKTISLRISNVFGPRQSIKGE-GNVVALFINK---ALKSSE--IDRFGDGTQT 204

Query: 618 RQFIYSLDLARAVHLG-SSGTTTVSNL 695
           R FIY  D+  A++    S  T V N+
Sbjct: 205 RDFIYVEDVVDAIYKALESDYTGVLNI 231


>UniRef50_A6BZU3 Cluster: Putative uncharacterized protein; n=1;
           Planctomyces maris DSM 8797|Rep: Putative
           uncharacterized protein - Planctomyces maris DSM 8797
          Length = 324

 Score = 35.5 bits (78), Expect = 1.3
 Identities = 46/187 (24%), Positives = 77/187 (41%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           GDLRD    E   A  +   V H AA+   +  ++ H LD     ++   ++L A  +  
Sbjct: 54  GDLRDLAAVEQATAGVEI--VFHQAALAS-VPRSVEHPLDTHEACVTGTVHVLDAARRSG 110

Query: 288 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 467
           V++VV   S+  + ++   P      H G        Y+ AK   ++  + +  SY    
Sbjct: 111 VQRVVYAGSSSAYGNQEQMP-----KHEGQTPEVLSPYAAAKLAGELYCQAFANSYDLET 165

Query: 468 TSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLA 647
             +   NVFGP  + +   S VIP        A+ +G     + G G   R F +  ++ 
Sbjct: 166 VRIRYFNVFGPRQDPNSPYSAVIPL----FTSALLEGRRPM-IFGDGLQSRDFTFVDNVV 220

Query: 648 RAVHLGS 668
           +A  L S
Sbjct: 221 QANILAS 227


>UniRef50_Q0C425 Cluster: DTDP-glucose 4,6-dehydratase; n=4;
           Proteobacteria|Rep: DTDP-glucose 4,6-dehydratase -
           Hyphomonas neptunium (strain ATCC 15444)
          Length = 365

 Score = 35.1 bits (77), Expect = 1.7
 Identities = 39/177 (22%), Positives = 78/177 (44%), Gaps = 5/177 (2%)
 Frame = +3

Query: 141 LFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTC 320
           +F   +P +V+HLAA    +  +++ +  F + N++   N+L+A      ++     S  
Sbjct: 75  IFLAERPDYVLHLAAET-HVDRSISGSQQFIQTNINGTYNLLEAARALQAERSGDLRSRF 133

Query: 321 IFPDKTTYPIDETMVHNG-----PPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPC 485
            F   +T  +  ++  +G       +  +  YS +K   D L + ++ +YG         
Sbjct: 134 RFLHVSTDEVYGSLGPDGLFSETTAYDPSSPYSASKAASDHLAKAWHRTYGLPVIVSNCS 193

Query: 486 NVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAV 656
           N +GPY +F      +IP +I    +  +       V G G  +R +++  D ARA+
Sbjct: 194 NNYGPY-HF---PEKLIPLIILNALEGQR-----LPVYGDGSNIRDWLHVEDHARAL 241


>UniRef50_A7HN54 Cluster: Polysaccharide biosynthesis protein CapD;
           n=2; Thermotogaceae|Rep: Polysaccharide biosynthesis
           protein CapD - Fervidobacterium nodosum Rt17-B1
          Length = 606

 Score = 35.1 bits (77), Expect = 1.7
 Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNL-DFFRENMSINDNILQACHKYN 287
           D+ DK   E +F  H+P  V H AA     F  M +NL +  R N+    N+ +    YN
Sbjct: 341 DVTDKNMMEKIFKTHRPDIVFHAAAHKHVFF--MQNNLYEALRVNVLGTINLAKLSCNYN 398

Query: 288 VKKVVSCLSTCIFPDKTTYP 347
           V+K V  +ST    DK  +P
Sbjct: 399 VEKFV-FIST----DKAVHP 413


>UniRef50_A4FLF3 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Saccharopolyspora erythraea NRRL 2338|Rep: NAD-dependent
           epimerase/dehydratase - Saccharopolyspora erythraea
           (strain NRRL 23338)
          Length = 324

 Score = 35.1 bits (77), Expect = 1.7
 Identities = 42/183 (22%), Positives = 72/183 (39%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           GDL D    EA   +     ++HLAA+   L  ++    + +  N+++   +L+      
Sbjct: 65  GDLGDPAAREAAVTEGA-AGIVHLAAITSVL-RSVDRPAETYAANVAVTQELLELARLRG 122

Query: 288 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 467
           + + V   +  +  D     I E++     P      Y   K   ++L  GY  +YG   
Sbjct: 123 LGQFVLASTNAVVGDIGRGTISESL-----PLRPLTPYGATKAACEMLLSGYAGAYGLAT 177

Query: 468 TSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLA 647
            ++   N++GP           IP L+R    A   G     V G G   R F++  D+ 
Sbjct: 178 CALRFTNIYGPGMG---HKDSFIPRLMR----AALAG-AGVEVYGDGSQSRDFVHVDDVV 229

Query: 648 RAV 656
           R V
Sbjct: 230 RGV 232


>UniRef50_A3LR65 Cluster: Putative dtdp-glucose 4,6-dehydratase;
           n=1; Pichia stipitis|Rep: Putative dtdp-glucose
           4,6-dehydratase - Pichia stipitis (Yeast)
          Length = 332

 Score = 35.1 bits (77), Expect = 1.7
 Identities = 39/176 (22%), Positives = 78/176 (44%), Gaps = 3/176 (1%)
 Frame = +3

Query: 144 FAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCI 323
           F  ++ T +++ AA    +  + +  L F R N+ +  N+L+ C +  +K+  S +S  +
Sbjct: 83  FPINQITDIVNFAAE-SSVDKSFSDPLYFTRNNILVTQNLLE-CMRL-LKQQNSQISVRL 139

Query: 324 FPDKTTYPIDETMVHN---GPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVF 494
               T     ++ + N   G    +N  Y+  K  ID++   Y  SY    T + P N++
Sbjct: 140 LHISTDEVYGDSDILNDEQGRLLPTN-PYAATKASIDLIIHSYQCSYDLSVTIIRPNNIY 198

Query: 495 GPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAVHL 662
           GP+         ++P  I R+   ++       + G G   R++++  D   A+ L
Sbjct: 199 GPHQ----YPDKIVPVTIERLTKGIK-----IPIHGIGSNKRRYLHVQDFLDALEL 245


>UniRef50_Q6D795 Cluster: Putative dTDP-glucose 4-6-dehydratase;
           n=1; Pectobacterium atrosepticum|Rep: Putative
           dTDP-glucose 4-6-dehydratase - Erwinia carotovora subsp.
           atroseptica (Pectobacterium atrosepticum)
          Length = 351

 Score = 34.7 bits (76), Expect = 2.3
 Identities = 41/165 (24%), Positives = 67/165 (40%), Gaps = 5/165 (3%)
 Frame = +3

Query: 168 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIF---PDKT 338
           +IH A +     H+ +  L  +   ++   N L+A  K      +  +S+C+    PD++
Sbjct: 105 IIHAAGIPNTRVHS-SDPLRVYETTVTGTANCLEAATKLGSLIRMVNVSSCLVNGQPDRS 163

Query: 339 --TYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNF 512
             T   D  M  +G  H     Y+ AKR  + L   Y   +    ++V P  + GPY   
Sbjct: 164 GATAEDDAFMQRSGELHGV---YAEAKRASETLATIYRNQHRLPISTVRPFTLAGPYHEL 220

Query: 513 SLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLA 647
            L       A+   M DA+     T  + G G   R ++Y  D A
Sbjct: 221 DLPW-----AINNFMRDAL--NGSTVRIHGDGNVRRSYLYGSDAA 258


>UniRef50_Q2JDH1 Cluster: NAD-dependent epimerase/dehydratase; n=21;
           cellular organisms|Rep: NAD-dependent
           epimerase/dehydratase - Frankia sp. (strain CcI3)
          Length = 360

 Score = 34.7 bits (76), Expect = 2.3
 Identities = 30/133 (22%), Positives = 49/133 (36%)
 Frame = +3

Query: 258 NILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNR 437
           N+L   ++ N + +++  S  ++ D   +P  E    +  P      Y  AKR  + L  
Sbjct: 101 NLLDLAYRKNARFLLASTSE-VYGDPRVHPQPEEYWGHVNPIGPRSMYDEAKRFAEALTT 159

Query: 438 GYNESYGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPL 617
            +  ++G     +   N +GP      +    IP  I     A        TV G G+  
Sbjct: 160 AHRATHGTSTGIIRIFNTYGP--RMRADDGRAIPTFI-----AQALRGQAVTVAGEGRQT 212

Query: 618 RQFIYSLDLARAV 656
           R   Y  DL   V
Sbjct: 213 RSLCYVDDLVEGV 225


>UniRef50_Q980W1 Cluster: UDP-glucose 4-epimerase; n=4;
           Sulfolobaceae|Rep: UDP-glucose 4-epimerase - Sulfolobus
           solfataricus
          Length = 311

 Score = 34.7 bits (76), Expect = 2.3
 Identities = 39/181 (21%), Positives = 78/181 (43%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           DLR +   E +    K   + HLAA    +  +M +  + F  ++ +  N+++   + + 
Sbjct: 48  DLR-QNMGELVEKLEKNPIIYHLAANPD-VRTSMINVEEHFERDVKVTLNVMELARRVDA 105

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 470
           +KV+   S+ ++ + +  P  E+      P S+   Y   K + + + + Y E YG    
Sbjct: 106 EKVIFTSSSTVYGETSKIPTPES--EELKPISN---YGLFKLLCENIVKYYAEQYGIKSI 160

Query: 471 SVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLAR 650
           S    N+ G        S  V+   I+++ D          ++G+GK  + ++Y  DL  
Sbjct: 161 STRLANITG-----GRVSHGVVIDFIKKLKD----NPNLLEILGNGKQRKSYLYIDDLIE 211

Query: 651 A 653
           A
Sbjct: 212 A 212


>UniRef50_Q97A88 Cluster: DTDP-glucose 4,6-dehydratase; n=2;
           cellular organisms|Rep: DTDP-glucose 4,6-dehydratase -
           Thermoplasma volcanium
          Length = 318

 Score = 34.7 bits (76), Expect = 2.3
 Identities = 38/145 (26%), Positives = 63/145 (43%), Gaps = 2/145 (1%)
 Frame = +3

Query: 228 FFRENMSINDNILQACHKYNVKKVVSCLSTC-IFPDKTTYPIDETMVHNG-PPHSSNFGY 401
           F R N     NIL+A  KY+++     +ST  +F    + P+D +   +   P++    Y
Sbjct: 95  FIRSNYVGVYNILEAVRKYDIR--FHQISTDEVFG---SLPLDSSQKFDEHSPYAPRNPY 149

Query: 402 SYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGD 581
           S  K   D+L R Y  +YG   T     N +GP    +     +IP  +       +   
Sbjct: 150 SATKAAADMLVRSYINTYGIKATISNCSNNYGP----NQHREKLIPKTVYNAIHNFR--- 202

Query: 582 PTFTVMGSGKPLRQFIYSLDLARAV 656
               + GSG+ +R +I+ LD   A+
Sbjct: 203 --IPIYGSGRQIRDWIHVLDHCSAI 225


>UniRef50_Q8ZW82 Cluster: UDP-glucose 4-epimerase; n=6;
           Thermoprotei|Rep: UDP-glucose 4-epimerase - Pyrobaculum
           aerophilum
          Length = 314

 Score = 34.7 bits (76), Expect = 2.3
 Identities = 23/90 (25%), Positives = 37/90 (41%)
 Frame = +3

Query: 231 FRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYA 410
           F EN+    N+L+   +  VK V+   S+ ++ D    P  E       P+     Y  A
Sbjct: 86  FNENVLATFNVLEWARQTGVKSVIFASSSTVYGDAEVIPTPEE-----APYKPISVYGAA 140

Query: 411 KRMIDVLNRGYNESYGCMFTSVIPCNVFGP 500
           K   +V+   Y   YG    ++   N+ GP
Sbjct: 141 KAAGEVMCATYARLYGVKCLAIRYANIIGP 170


>UniRef50_Q5UYL1 Cluster: UDP-glucose 4-epimerase; n=5;
           Halobacteriaceae|Rep: UDP-glucose 4-epimerase -
           Haloarcula marismortui (Halobacterium marismortui)
          Length = 334

 Score = 34.7 bits (76), Expect = 2.3
 Identities = 43/183 (23%), Positives = 72/183 (39%)
 Frame = +3

Query: 105 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 284
           +GD+RD      L A     +V H AA  G +  ++ +   +   N++   N+L AC   
Sbjct: 70  EGDVRDAELVTDLVAD--ADYVYHQAAQAG-VRPSVKNPRKYDEVNVNGTLNLLDACRDE 126

Query: 285 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
            +++ V   S+ ++      P DE   H   P S    Y  +K   +     Y+E Y   
Sbjct: 127 GIERFVMASSSSVYGKPQYLPYDEQ--HPTTPVSP---YGASKLAAERYACAYSEVYDLS 181

Query: 465 FTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDL 644
             ++    V+GP     +  +  I   + R       G+P   + G G   R F Y  D+
Sbjct: 182 TVALRYFTVYGP----RMRPNMAISNFVSR----CHNGEPP-VIYGDGTQTRDFTYIEDV 232

Query: 645 ARA 653
             A
Sbjct: 233 IDA 235


>UniRef50_P18645 Cluster: UDP-glucose 4-epimerase; n=353; cellular
           organisms|Rep: UDP-glucose 4-epimerase - Rattus
           norvegicus (Rat)
          Length = 347

 Score = 34.7 bits (76), Expect = 2.3
 Identities = 24/91 (26%), Positives = 42/91 (46%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           D+ D+   + LF KH    VIH A +   +  ++   LD++R N++    +L+      V
Sbjct: 66  DILDQAALQHLFKKHNFKAVIHFAGL-KAVGESVQKPLDYYRVNLTGTIQLLEIMRAMGV 124

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPH 383
           K +V   S  ++      P+  +    GPPH
Sbjct: 125 KSLVFSSSATVYGK----PVPAS--GRGPPH 149


>UniRef50_Q1YQ08 Cluster: Oxidoreductase; n=1; gamma proteobacterium
           HTCC2207|Rep: Oxidoreductase - gamma proteobacterium
           HTCC2207
          Length = 336

 Score = 34.3 bits (75), Expect = 3.0
 Identities = 26/111 (23%), Positives = 45/111 (40%)
 Frame = +3

Query: 168 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 347
           +IH AA+V     N   + D +R N+    N++ A  KYNV++ V   S   + +     
Sbjct: 76  IIHTAALVS----NALSDADMWRVNVQATANLIAAAEKYNVRRFVQLSSIVAYGNSAAGE 131

Query: 348 IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGP 500
           + E    + P H+    Y   K   +      +         + P +V+GP
Sbjct: 132 LCE----DHPVHADGGSYVLTKLASEHAVLAAHAKGNIEIVIIRPGDVYGP 178


>UniRef50_A7I3Y2 Cluster: Putative zinc protease; n=1; Campylobacter
           hominis ATCC BAA-381|Rep: Putative zinc protease -
           Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 /
           NCTC 13146 /CH001A)
          Length = 915

 Score = 34.3 bits (75), Expect = 3.0
 Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 8/79 (10%)
 Frame = +3

Query: 144 FAKHKPTHVIHLAAMVG-----GLFHNMAHNLDFFRENMSINDNILQACHKYN---VKKV 299
           F+  + T +  LA M+      G F+N   N+    EN S+N ++   C +YN    KK 
Sbjct: 537 FSNFENTKIARLAVMISNESGLGGFNNYETNIITANENFSLNKSLNDICVEYNSLSSKKD 596

Query: 300 VSCLSTCIFPDKTTYPIDE 356
           VS     IF D     IDE
Sbjct: 597 VSNALKAIFADIKNAKIDE 615


>UniRef50_A0BCG5 Cluster: Chromosome undetermined scaffold_10, whole
           genome shotgun sequence; n=8; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_10,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 1051

 Score = 34.3 bits (75), Expect = 3.0
 Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
 Frame = +3

Query: 177 LAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCI--FPDKTTYPI 350
           L AM  G F  ++  LD F  +    DNI+    K+N K + S   T I  +PD+ T   
Sbjct: 96  LQAMTSGNFPPLSKLLDNFHASEIKEDNIMFQMKKFNKKTLFSGDDTWIGLYPDQFTLQF 155

Query: 351 DETMVHNGPPHSSNFGYSYAKRMIDVLNRGYN 446
            +   + G  HS +       ++++ L++GY+
Sbjct: 156 PQKSFNIGDMHSVD--QFNCDKILENLDKGYD 185


>UniRef50_Q9UXL5 Cluster: DTDP-glucose 4,6-dehydratase; n=1;
           Sulfolobus solfataricus|Rep: DTDP-glucose
           4,6-dehydratase - Sulfolobus solfataricus
          Length = 317

 Score = 34.3 bits (75), Expect = 3.0
 Identities = 48/182 (26%), Positives = 76/182 (41%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           D+R +   + +  ++ P  VI+ AA    +  ++    DF   N+    N+L+A  K+N 
Sbjct: 53  DVRSEKMHD-IIKEYSPDIVINFAAETH-VDRSIYKPQDFVTTNVLGTVNLLEASRKFNF 110

Query: 291 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 470
           K V   +ST        Y  +E    N P   S+  YS +K   D+  + Y  +YG    
Sbjct: 111 KYVH--IST-----DEVYG-EECGDENSPLKPSS-PYSASKASADLFVKAYVRTYGISAV 161

Query: 471 SVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLAR 650
            V P N +GP          +  A+IR +            V G GK  R +I+  D AR
Sbjct: 162 IVRPSNNYGPR---QFPEKLIPKAIIRTLLGI------HIPVYGDGKAERDWIFVEDTAR 212

Query: 651 AV 656
            +
Sbjct: 213 II 214


>UniRef50_P44914 Cluster: dTDP-glucose 4,6-dehydratase; n=117;
           Bacteria|Rep: dTDP-glucose 4,6-dehydratase - Haemophilus
           influenzae
          Length = 338

 Score = 34.3 bits (75), Expect = 3.0
 Identities = 42/190 (22%), Positives = 82/190 (43%), Gaps = 6/190 (3%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQAC----H 278
           D+ D    E +F K++P  V+HLAA    +  +++   DF + N+     +L+      H
Sbjct: 59  DICDLNVIENIFEKYQPDAVMHLAA-ESHVDRSISGAADFVQTNIVGTYTLLEVAKNYWH 117

Query: 279 KYNVKKVVSCLSTCIFPDKT--TYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNES 452
             +  K  +     I  D+      + E       P+  +  YS +K   + L + ++ +
Sbjct: 118 TLDEAKKTTFRFHHISTDEVYGDLSLSEPAFTEQSPYHPSSPYSASKAASNHLVQAWHRT 177

Query: 453 YGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIY 632
           YG         N +G Y +    +  +IP +I    +A+  G P   + G G+ +R +++
Sbjct: 178 YGLPVIITNSSNNYGAYQH----AEKLIPLMI---SNAVM-GKP-LPIYGDGQQIRDWLF 228

Query: 633 SLDLARAVHL 662
             D  +A +L
Sbjct: 229 VEDHVQASYL 238


>UniRef50_UPI00015BAE89 Cluster: NAD-dependent
           epimerase/dehydratase; n=1; Ignicoccus hospitalis
           KIN4/I|Rep: NAD-dependent epimerase/dehydratase -
           Ignicoccus hospitalis KIN4/I
          Length = 293

 Score = 33.9 bits (74), Expect = 4.0
 Identities = 40/165 (24%), Positives = 70/165 (42%)
 Frame = +3

Query: 168 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 347
           V HLAA +     ++       R N+    N+L+A    +   VV   +  ++ +    P
Sbjct: 61  VYHLAAEIKAE-ESLREPAKVVRVNVEGTLNVLEAARLADAS-VVFASTAAVYGEAKVVP 118

Query: 348 IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESS 527
           + E   H  P    N  Y   K   + L   Y +++G    ++   NV+GP  +    S 
Sbjct: 119 VPEE--H--PLEPVNV-YGATKVAGEALVNSYRKAFGLRAWTLRLFNVYGPSAS---PSR 170

Query: 528 HVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDLARAVHL 662
            V+   +RR      KG+P   + G G+ +R F++  D+ +A  L
Sbjct: 171 GVVGEFLRRA----LKGEP-LRIYGDGRQVRDFVFVDDVVKAFKL 210


>UniRef50_Q8A3S4 Cluster: Putative nucleotide-sugar dehydratase;
           n=1; Bacteroides thetaiotaomicron|Rep: Putative
           nucleotide-sugar dehydratase - Bacteroides
           thetaiotaomicron
          Length = 344

 Score = 33.9 bits (74), Expect = 4.0
 Identities = 25/114 (21%), Positives = 49/114 (42%), Gaps = 1/114 (0%)
 Frame = +3

Query: 165 HVIHLAAMVG-GLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTT 341
           ++IH A+  G   FHN    +   + N+   DN+     ++N+++++   S  ++ +   
Sbjct: 95  YIIHAASYAGPAAFHN--DPVGVMKANILGVDNLFSYGEQHNLRRLLYVSSGEVYGEGNG 152

Query: 342 YPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPY 503
            P  E    +    S    Y  AKR  + L   Y   +        PC+++GP+
Sbjct: 153 IPFREEDSGSLDWASLRACYPAAKRTAETLCIAYAAQFQIETVIARPCHIYGPF 206


>UniRef50_Q65D61 Cluster: Putative uncharacterized protein; n=1;
           Bacillus licheniformis ATCC 14580|Rep: Putative
           uncharacterized protein - Bacillus licheniformis (strain
           DSM 13 / ATCC 14580)
          Length = 331

 Score = 33.9 bits (74), Expect = 4.0
 Identities = 27/132 (20%), Positives = 55/132 (41%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           GD+RD+   + +F       V+H AA    +     +    F EN++  + +L    +Y+
Sbjct: 50  GDIRDRHFLKQVFENEDIEAVMHFAA--SPISSKSKNVFTSFNENITGMETLLDVMKEYD 107

Query: 288 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 467
           V ++V   S  ++      P+ E      P H+    +   K M++ +     ++YG  +
Sbjct: 108 VGRIVFASSAAVYGSPEDLPVTEE-TEPEPVHA----HGKVKWMMEKMLMEAEKAYGLKY 162

Query: 468 TSVIPCNVFGPY 503
             +   N  G +
Sbjct: 163 VILRSFNACGAH 174


>UniRef50_Q1K169 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Desulfuromonas acetoxidans DSM 684|Rep: NAD-dependent
           epimerase/dehydratase - Desulfuromonas acetoxidans DSM
           684
          Length = 310

 Score = 33.9 bits (74), Expect = 4.0
 Identities = 41/159 (25%), Positives = 65/159 (40%)
 Frame = +3

Query: 168 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 347
           ++HLAA +  +  ++    +    N+    N+L+    +++   V   S  I+ +    P
Sbjct: 71  IVHLAA-IASVQASVEAPRETHAINLDGTINMLEVARIHDISTFVFASSAAIYGNNQQLP 129

Query: 348 IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESS 527
           + E    + PP      Y+  K   +     Y   +    T+    NV+GP  + S   S
Sbjct: 130 LKE----DTPPAPLT-PYAVDKLGSEYYIDFYCRQFKLKTTTFRFFNVYGPRQDPSSPYS 184

Query: 528 HVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDL 644
            VI  L   MD A  K    FTV G G   R FI+  DL
Sbjct: 185 GVISIL---MDRAQNKRP--FTVFGDGLQSRDFIFVKDL 218


>UniRef50_A7HHX8 Cluster: NAD-dependent epimerase/dehydratase; n=4;
           Cystobacterineae|Rep: NAD-dependent
           epimerase/dehydratase - Anaeromyxobacter sp. Fw109-5
          Length = 317

 Score = 33.9 bits (74), Expect = 4.0
 Identities = 34/135 (25%), Positives = 60/135 (44%), Gaps = 5/135 (3%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAH-NLDFFRENMSINDNILQACHKYN 287
           DLR K + E +F +H+P  +IH+     G+ H+      +    N+     IL  C ++ 
Sbjct: 61  DLR-KARVEEVFRRHRPEALIHM-----GIMHDPRDPRSEAHSFNVLGTHKILDLCVRHG 114

Query: 288 VKKVVSCLSTCIF---PDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 458
           VKK V   S  ++   PD + +  +ET +  G      F        +D+  + +   + 
Sbjct: 115 VKKAVVLSSANVYGPRPDNSNFLPEETPLMAG----ERFSEMRDLIELDMYAQSFMWKHP 170

Query: 459 CMFTSVI-PCNVFGP 500
            + T V+ P N+ GP
Sbjct: 171 ELETVVLRPVNIIGP 185


>UniRef50_A3DIS0 Cluster: Polysaccharide biosynthesis protein CapD
           precursor; n=1; Clostridium thermocellum ATCC 27405|Rep:
           Polysaccharide biosynthesis protein CapD precursor -
           Clostridium thermocellum (strain ATCC 27405 / DSM 1237)
          Length = 607

 Score = 33.9 bits (74), Expect = 4.0
 Identities = 19/65 (29%), Positives = 33/65 (50%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           G +RDK + + +F+++KP  V H AA          +  +  + N+    N+ +  H+YN
Sbjct: 338 GSIRDKKRLDYVFSQYKPGIVFHAAAHKHVPLMEF-NPQEAVKNNVFGTLNVAECAHQYN 396

Query: 288 VKKVV 302
            KK V
Sbjct: 397 CKKFV 401


>UniRef50_A0L9M4 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Magnetococcus sp. MC-1|Rep: NAD-dependent
           epimerase/dehydratase - Magnetococcus sp. (strain MC-1)
          Length = 330

 Score = 33.9 bits (74), Expect = 4.0
 Identities = 23/71 (32%), Positives = 41/71 (57%), Gaps = 1/71 (1%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRE-NMSINDNILQACHKYN 287
           D+RD+   +ALFA+ +   VIHLAA+VG      A   +  ++ N   + ++L+A  ++ 
Sbjct: 56  DIRDREAMQALFAQTQFHGVIHLAAIVGD--PACARQSELAQQTNWQASIDLLEASKQHG 113

Query: 288 VKKVVSCLSTC 320
           V++ +   STC
Sbjct: 114 VERFIFA-STC 123


>UniRef50_Q5DAK3 Cluster: SJCHGC01535 protein; n=2; Schistosoma
           japonicum|Rep: SJCHGC01535 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 249

 Score = 33.9 bits (74), Expect = 4.0
 Identities = 16/45 (35%), Positives = 30/45 (66%), Gaps = 2/45 (4%)
 Frame = +3

Query: 243 MSINDN--ILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHN 371
           +SIND+  I Q+ + Y++ K++S  S C+ P++T +   E +V+N
Sbjct: 141 LSINDSEVIDQSNYVYDIYKMISSQSNCLLPEETIWCSTEDLVNN 185


>UniRef50_Q7VRZ4 Cluster: Thymidine diphosphoglucose
           4,6-dehydratase; n=2; Bordetella|Rep: Thymidine
           diphosphoglucose 4,6-dehydratase - Bordetella pertussis
          Length = 326

 Score = 33.5 bits (73), Expect = 5.3
 Identities = 19/73 (26%), Positives = 34/73 (46%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           GD+R     +A   +H    V+H AA+  GL        D F  N+     +++A  ++ 
Sbjct: 55  GDVRRGADLDAALREHAVDRVVHGAAVTAGLEREKNAAADIFTVNLLGAVKVMEAGLRHG 114

Query: 288 VKKVVSCLSTCIF 326
           V++VV   +  +F
Sbjct: 115 VRQVVQLGTGSVF 127


>UniRef50_Q7NRA0 Cluster: UDP-glucose 4-epimerase; n=1;
           Chromobacterium violaceum|Rep: UDP-glucose 4-epimerase -
           Chromobacterium violaceum
          Length = 326

 Score = 33.5 bits (73), Expect = 5.3
 Identities = 47/181 (25%), Positives = 69/181 (38%), Gaps = 2/181 (1%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 287
           GD+RD       F + + THV+H A        N    L  F   +S    +L    +  
Sbjct: 64  GDVRDFD-----FPRERFTHVLHAATTSAHETFNGESPLGKFDTLVSGTRRVLDFAAEAG 118

Query: 288 VKKVVSCLSTCIF-PDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
           V+  +   S   + P     P+ E  V              AKR  + L   Y   YG  
Sbjct: 119 VRHFLFTSSGAAYGPSPRGLPLREDDVCAPDTMDPMTALGQAKRAAEFLCAAYARQYG-W 177

Query: 465 FTSVIPCNVF-GPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLD 641
             S   C  F GP+    L+  + I   I+    A+Q G+P   + G G P+R ++Y  D
Sbjct: 178 HLSAARCFAFVGPF--MPLDIHYAIGNFIQC---ALQ-GEPII-INGDGSPVRSYLYMGD 230

Query: 642 L 644
           L
Sbjct: 231 L 231


>UniRef50_Q1MP11 Cluster: Nucleoside-diphosphate-sugar epimerases;
           n=1; Lawsonia intracellularis PHE/MN1-00|Rep:
           Nucleoside-diphosphate-sugar epimerases - Lawsonia
           intracellularis (strain PHE/MN1-00)
          Length = 339

 Score = 33.5 bits (73), Expect = 5.3
 Identities = 19/69 (27%), Positives = 35/69 (50%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           ++ D +  E LF+K+    VIH A     +  ++   L++++ N +    IL+ C KYN 
Sbjct: 59  NVEDTSMMEVLFSKYTFDAVIHFAG-YKSIAESLKIPLEYYQNNYNSTLTILRLCLKYNS 117

Query: 291 KKVVSCLST 317
             + S  +T
Sbjct: 118 TFIFSSSAT 126


>UniRef50_A3ZSY0 Cluster: CDP glucose 4,6-dehydratase; n=1;
           Blastopirellula marina DSM 3645|Rep: CDP glucose
           4,6-dehydratase - Blastopirellula marina DSM 3645
          Length = 368

 Score = 33.5 bits (73), Expect = 5.3
 Identities = 30/119 (25%), Positives = 53/119 (44%), Gaps = 3/119 (2%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAM-VGGLFHNMAHNLDFFRENMSINDNILQACHKY 284
           GD+RD ++ + +F    P  V+HLAA  +  L + +   L+ F  N+    N+L+AC   
Sbjct: 67  GDIRDLSKLKQVFQDFDPEIVLHLAAQPLVRLSYEIP--LETFDVNVLGTANVLEACRGL 124

Query: 285 NVKKVVSCLST--CIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESY 455
              +    ++T  C    +  +   ET      P      YS +K   +++   Y +SY
Sbjct: 125 QSLQAAVMVTTDKCYENREWDWSYRET-----DPLGGKDPYSASKACAEIVTSSYRDSY 178


>UniRef50_Q5UWG0 Cluster: UDP-glucose 4-epimerase; n=1; Haloarcula
           marismortui|Rep: UDP-glucose 4-epimerase - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 319

 Score = 33.5 bits (73), Expect = 5.3
 Identities = 31/135 (22%), Positives = 54/135 (40%), Gaps = 3/135 (2%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFH-NMAHNLDFFRENMSINDNILQACHKY 284
           GD+ + T       +   TH++HLAA++      N    LD    N+   +N+ +A    
Sbjct: 56  GDVSEATDVIHAVKETGTTHIVHLAALLTNTARDNPRAGLDV---NIKGTNNVFEAARTL 112

Query: 285 N--VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 458
           +  +++V    S  ++     Y   E +  N   +     Y   K   +   R Y+E YG
Sbjct: 113 DDQIERVTWASSAAVYAPPHNYA--EYVDENELVYPDTL-YGATKEYNEHQARVYHEDYG 169

Query: 459 CMFTSVIPCNVFGPY 503
                + P   +GPY
Sbjct: 170 VDHVGLRPTVAYGPY 184


>UniRef50_Q8DGV6 Cluster: UDP-glucose 4-epimerase; n=1;
           Synechococcus elongatus|Rep: UDP-glucose 4-epimerase -
           Synechococcus elongatus (Thermosynechococcus elongatus)
          Length = 308

 Score = 33.1 bits (72), Expect = 7.0
 Identities = 48/213 (22%), Positives = 87/213 (40%), Gaps = 17/213 (7%)
 Frame = +3

Query: 108 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLD-FFRENMSINDNILQACHKY 284
           GD+ D+   + LF  +  T V+H AA +        H+ D F++ N+     +LQA    
Sbjct: 26  GDIGDRPLLDWLFQTYPVTAVMHFAAYIE--VGESIHSPDRFYQNNVHGALTLLQAMVAA 83

Query: 285 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
            +   +   +  ++      PI ET      P +    Y  +K M++ +      +YG  
Sbjct: 84  KIPYFIFSSTAAVYGVPPEIPISETC-----PCAPINPYGRSKWMVEQMVADMGTAYGLK 138

Query: 465 FTSVIPCNVFG--PYDNFSLE---SSHVIPALIRRMDDAMQKGDPTFTVMGSGKP----- 614
                  N  G  P+     +    +H+IP +++    A     P   + G+  P     
Sbjct: 139 SVIFRYFNAAGADPHSRLGEDHRPETHLIPLVLQ----AAMGRRPHIAIYGTDYPTPDGT 194

Query: 615 -LRQFIYSLDLARA-----VHLGSSGTTTVSNL 695
            +R +I+ +DLA+A      +L S G + + NL
Sbjct: 195 CIRDYIHVVDLAQAHVRGLKYLLSGGNSQIFNL 227


>UniRef50_Q2J7B4 Cluster: NAD-dependent epimerase/dehydratase; n=3;
           Frankia|Rep: NAD-dependent epimerase/dehydratase -
           Frankia sp. (strain CcI3)
          Length = 347

 Score = 33.1 bits (72), Expect = 7.0
 Identities = 21/63 (33%), Positives = 30/63 (47%)
 Frame = +3

Query: 441 YNESYGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLR 620
           Y  S+G    +V   +VFGPY +    + H   A++    +A   G P  TV G G+  R
Sbjct: 166 YQASFGLPVLTVRLFDVFGPYQS----AGHAYAAVVPTFIEAALAGRP-LTVRGDGRQTR 220

Query: 621 QFI 629
            FI
Sbjct: 221 DFI 223


>UniRef50_Q2CH75 Cluster: DTDP-glucose 4,6-dehydratase; n=1;
           Oceanicola granulosus HTCC2516|Rep: DTDP-glucose
           4,6-dehydratase - Oceanicola granulosus HTCC2516
          Length = 303

 Score = 33.1 bits (72), Expect = 7.0
 Identities = 37/168 (22%), Positives = 66/168 (39%), Gaps = 1/168 (0%)
 Frame = +3

Query: 3   SGLVGQAIKTVIERD-RQKRNSDYDSETWIFSGSKDGDLRDKTQTEALFAKHKPTHVIHL 179
           +GL+G A++  + RD R    +D               L+D    E L  +     +IH 
Sbjct: 9   AGLIGMALRARLARDGRAVVATDMSRHGRDDPELVVLPLQDGEALERLARERGVEAIIHC 68

Query: 180 AAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYPIDET 359
            A + G  H     L+    N+  +  ++    +  +++ V C S  ++ +     I E 
Sbjct: 69  GA-ISGPMHAPGRPLEVVDVNIRASAVLMDIARRLEMRRFVMCSSIGVYGNAGPGRIGED 127

Query: 360 MVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPY 503
           +    P H ++  Y  +K   D L  G+   YG     +    V+GPY
Sbjct: 128 L----PLHPTSV-YGASKVAGDALLDGFAAEYGLDGVGLRIARVYGPY 170


>UniRef50_Q1NXD3 Cluster: NAD-dependent
           epimerase/dehydratase:dTDP-4-dehydrorhamnose reductase;
           n=1; delta proteobacterium MLMS-1|Rep: NAD-dependent
           epimerase/dehydratase:dTDP-4-dehydrorhamnose reductase -
           delta proteobacterium MLMS-1
          Length = 292

 Score = 33.1 bits (72), Expect = 7.0
 Identities = 26/94 (27%), Positives = 43/94 (45%)
 Frame = +3

Query: 381 HSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMD 560
           H   F YS  KR  + L   Y  ++G  +  +  CNV+GP D  +  +     AL + + 
Sbjct: 117 HPKGF-YSITKRAAEELLVSYCRTFGIDYRILRLCNVYGPGDGGAAAAPGKKNAL-QFII 174

Query: 561 DAMQKGDPTFTVMGSGKPLRQFIYSLDLARAVHL 662
           D +Q  +P     G G   R +++  D+  A+ L
Sbjct: 175 DRLQNNEPVDLYHG-GHFYRDYLHVDDVVTAIDL 207


>UniRef50_Q1MNV8 Cluster: Nucleoside-diphosphate-sugar epimerases;
           n=4; Bacteria|Rep: Nucleoside-diphosphate-sugar
           epimerases - Lawsonia intracellularis (strain
           PHE/MN1-00)
          Length = 321

 Score = 33.1 bits (72), Expect = 7.0
 Identities = 42/202 (20%), Positives = 78/202 (38%)
 Frame = +3

Query: 105 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 284
           +GDL D       FA  +   VIHL+A     F  + H      +N     N+L+A   +
Sbjct: 54  EGDLLDTKALSKAFATGE--QVIHLSANADVRF-GVEHPSKDLEQNAIATHNVLEAMRLH 110

Query: 285 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
           N+K++    +  ++ + +  P  E    + P       Y+ +K   +     Y ES+  +
Sbjct: 111 NIKRIAFASTGSVYGEASIIPTPE----DAPFPIQTSLYAASKLSGEGFIEAYCESFDFI 166

Query: 465 FTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDL 644
                  ++ GP         HV         + ++K     TV+G+G   + +++  D 
Sbjct: 167 GHIFRFVSILGP----RYTHGHVFD-----FCNQLRKDPSKLTVLGNGTQRKSYLHVDDC 217

Query: 645 ARAVHLGSSGTTTVSNLLSYQL 710
             A+ L      T + +  Y L
Sbjct: 218 IDAMLLAIEKAPTDTKVHIYNL 239


>UniRef50_Q124Y5 Cluster: NAD-dependent epimerase/dehydratase; n=5;
           Proteobacteria|Rep: NAD-dependent epimerase/dehydratase
           - Polaromonas sp. (strain JS666 / ATCC BAA-500)
          Length = 290

 Score = 33.1 bits (72), Expect = 7.0
 Identities = 39/160 (24%), Positives = 72/160 (45%), Gaps = 2/160 (1%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           DL D    +A  A  +P+HV+HLAA+    F   A    F+  N+    N+L A     +
Sbjct: 33  DLTDAEALKAEVASIQPSHVVHLAAI---SFVGHADVRAFYDVNLFGTLNLLNAIAALEI 89

Query: 291 --KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
             + V+   S  ++ +    PI E  +   P   +++G S  K  ++ L R Y++     
Sbjct: 90  SPRSVILTSSANVYGNCAASPIPEDQI---PAPLNHYGIS--KLAMEHLARTYSD----- 139

Query: 465 FTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDP 584
              ++P  +  P+ N++  S   +  +I ++ D   +G P
Sbjct: 140 ---ILPIVIVRPF-NYT-GSGQALTFVIPKLIDHFSRGAP 174


>UniRef50_Q0F315 Cluster: DTDP-D-glucose 4,6-dehydratase; n=3;
           Proteobacteria|Rep: DTDP-D-glucose 4,6-dehydratase -
           Mariprofundus ferrooxydans PV-1
          Length = 367

 Score = 33.1 bits (72), Expect = 7.0
 Identities = 26/87 (29%), Positives = 40/87 (45%)
 Frame = +3

Query: 381 HSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMD 560
           ++ N  YS +K   D L R +  +YG   T+    N +GPY +        IP +IR   
Sbjct: 184 YAPNSPYSASKAGSDHLVRAWFHTYGLPVTTTNCSNNYGPYQH----GEKFIPTVIR--- 236

Query: 561 DAMQKGDPTFTVMGSGKPLRQFIYSLD 641
            +  +G P   V G G  +R ++Y  D
Sbjct: 237 -SCLEGKP-IPVYGDGSNIRDWLYVED 261


>UniRef50_A6H035 Cluster: GDP-4-dehydro-D-rhamnose reductase; n=1;
           Flavobacterium psychrophilum JIP02/86|Rep:
           GDP-4-dehydro-D-rhamnose reductase - Flavobacterium
           psychrophilum (strain JIP02/86 / ATCC 49511)
          Length = 297

 Score = 33.1 bits (72), Expect = 7.0
 Identities = 30/136 (22%), Positives = 64/136 (47%), Gaps = 3/136 (2%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQAC---HK 281
           +L +K +  A+  + +P+ VIHLAA +  + H   +  + +  N+    N+L+A     K
Sbjct: 50  NLLEKEKLSAIIKEIQPSIVIHLAA-ISFVGHENLN--EMYDVNVIGTQNLLEAIKNESK 106

Query: 282 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 461
            +++K++   S  ++ ++T   + E +  N   H     Y  +K  ++ + + Y ++   
Sbjct: 107 DSIRKIIIASSATVYGNQTETVLSEALCPNPVNH-----YGISKLAMEFVAKTYFDTLPI 161

Query: 462 MFTSVIPCNVFGPYDN 509
           + T   P N   P  N
Sbjct: 162 IITR--PFNYTAPEQN 175


>UniRef50_A3CKR6 Cluster: Nucleoside-diphosphate-sugar epimerase,
           putative; n=2; Streptococcus|Rep:
           Nucleoside-diphosphate-sugar epimerase, putative -
           Streptococcus sanguinis (strain SK36)
          Length = 350

 Score = 33.1 bits (72), Expect = 7.0
 Identities = 25/124 (20%), Positives = 54/124 (43%), Gaps = 1/124 (0%)
 Frame = +3

Query: 168 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 347
           + H AA     +    H  + +  N+   +N+L+A ++  +++ V   S  +   +    
Sbjct: 83  LFHTAAFFRDNYKGGKHWQELYDTNIIGTNNLLEAAYEAGIRQFVHTSSCVVLEGEANQL 142

Query: 348 IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF-TSVIPCNVFGPYDNFSLES 524
           IDE+M  +     + F Y  +K + +   R + + +  +F   ++P  + GP D     S
Sbjct: 143 IDESMSRS---KDTPFDYYRSKILSEEAVRDFLDKHSDVFGCFILPSVMLGPRDLGPTSS 199

Query: 525 SHVI 536
             +I
Sbjct: 200 GQMI 203


>UniRef50_Q2UMZ8 Cluster: Nucleoside-diphosphate-sugar epimerases;
           n=2; Aspergillus|Rep: Nucleoside-diphosphate-sugar
           epimerases - Aspergillus oryzae
          Length = 339

 Score = 33.1 bits (72), Expect = 7.0
 Identities = 39/154 (25%), Positives = 61/154 (39%), Gaps = 8/154 (5%)
 Frame = +3

Query: 258 NILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNR 437
           N+L      N + V+   ++ ++ D   +P  ET   N  P      Y   KR+ + L  
Sbjct: 120 NVLDLAISKNAR-VLHTSTSEVYGDPLVHPQPETYWGNVNPFGMRSCYDEGKRVAEALCY 178

Query: 438 GYNESYGCMFTSVIPCNVFGPYDNFS---LESSHVIPALIRRMDDAMQKGDPTFT----- 593
            Y E  G         N +GP  N S   + S+ ++ AL    +D    GD T T     
Sbjct: 179 AYREQQGADIRIARIFNTYGPRMNGSDGRVVSNFIVAAL--SGEDLKITGDGTATRSFQY 236

Query: 594 VMGSGKPLRQFIYSLDLARAVHLGSSGTTTVSNL 695
           V    K L + + S      V++G+ G  T+  L
Sbjct: 237 VTDCMKGLYRLMNSDYSEGPVNIGNDGEFTIQQL 270


>UniRef50_Q9HSU9 Cluster: GDP-D-mannose dehydratase; n=2;
           Halobacterium salinarum|Rep: GDP-D-mannose dehydratase -
           Halobacterium salinarium (Halobacterium halobium)
          Length = 309

 Score = 33.1 bits (72), Expect = 7.0
 Identities = 33/141 (23%), Positives = 59/141 (41%)
 Frame = +3

Query: 261 ILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRG 440
           ++ A  + +V  VV   S  I+    T+P  E+M     P S    Y+ +K   + L   
Sbjct: 104 VIDAAREADVDTVVVASSAAIYGSTETFPKVESMTEQ--PESP---YALSKHYTEKLALQ 158

Query: 441 YNESYGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLR 620
            +E Y     ++   N++GP  + + + + VIP  I  M D  +       + G G+  R
Sbjct: 159 ASELYDIDTAALRYFNIYGPRQDPNGDYAAVIPKFISLMLDGERP-----VIYGDGEQSR 213

Query: 621 QFIYSLDLARAVHLGSSGTTT 683
            F +  +  +A    + G  T
Sbjct: 214 DFTFIDNAIQANIRAAEGDVT 234


>UniRef50_Q18Z69 Cluster: CDP-glucose 4,6-dehydratase; n=1;
           Desulfitobacterium hafniense DCB-2|Rep: CDP-glucose
           4,6-dehydratase - Desulfitobacterium hafniense (strain
           DCB-2)
          Length = 139

 Score = 32.7 bits (71), Expect = 9.3
 Identities = 20/77 (25%), Positives = 34/77 (44%)
 Frame = +3

Query: 99  SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACH 278
           S + D+RD+    A F  +KP  V HLAA    + ++     + F  N+    N+L+A  
Sbjct: 64  SIEDDVRDEAALMAAFRTYKPDIVFHLAAQ-PLVRYSYLEPKETFETNVMGTVNVLEAAR 122

Query: 279 KYNVKKVVSCLSTCIFP 329
                + +  +  C  P
Sbjct: 123 STETVQSIVVIRACFIP 139


>UniRef50_Q9SGX0 Cluster: F1N19.2; n=1; Arabidopsis thaliana|Rep:
           F1N19.2 - Arabidopsis thaliana (Mouse-ear cress)
          Length = 447

 Score = 32.7 bits (71), Expect = 9.3
 Identities = 19/72 (26%), Positives = 36/72 (50%)
 Frame = +3

Query: 111 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 290
           DLRDK   E +F++ K   V+H A +   +  ++A  L ++  N+     +L+    +  
Sbjct: 126 DLRDKPALEKVFSETKFDAVMHFAGL-KAVGESVAKPLLYYNNNLIATITLLEVMAAHGC 184

Query: 291 KKVVSCLSTCIF 326
           KK+V   S  ++
Sbjct: 185 KKLVFSSSATVY 196


>UniRef50_A7QYR5 Cluster: Chromosome chr5 scaffold_253, whole genome
           shotgun sequence; n=7; core eudicotyledons|Rep:
           Chromosome chr5 scaffold_253, whole genome shotgun
           sequence - Vitis vinifera (Grape)
          Length = 581

 Score = 32.7 bits (71), Expect = 9.3
 Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 2/134 (1%)
 Frame = +3

Query: 258 NILQACHKYNVKKVVSCLSTCIFPDKT--TYPIDETMVHNGPPHSSNFGYSYAKRMIDVL 431
           N++ AC +  VK+++   S  +  D +   Y  DE++     P       +  K   + L
Sbjct: 113 NVINACQECKVKRLIYNSSADVVFDGSHDIYNGDESLPC---PWKFEDMLTDIKAQAEGL 169

Query: 432 NRGYNESYGCMFTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGK 611
               N   G +  ++ PCNVFGP D        ++P L+ +     + G   F V+GSG+
Sbjct: 170 VLIANNIDGLVTCALRPCNVFGPGD------KQLVPFLVNK----AKSGHAKF-VIGSGE 218

Query: 612 PLRQFIYSLDLARA 653
            +  F Y  ++A A
Sbjct: 219 NMSDFTYVENVAHA 232


>UniRef50_A1RW61 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Thermofilum pendens Hrk 5|Rep: NAD-dependent
           epimerase/dehydratase - Thermofilum pendens (strain Hrk
           5)
          Length = 308

 Score = 32.7 bits (71), Expect = 9.3
 Identities = 48/183 (26%), Positives = 76/183 (41%)
 Frame = +3

Query: 105 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 284
           +GD+RD        +      VIHLAA+V  +  +     +++  N+     +L    + 
Sbjct: 52  EGDVRDAEALRRFLSGVDA--VIHLAALVD-VRESEERPEEYWSVNVEGTRALLAEASRA 108

Query: 285 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 464
            V+KVV   S  ++ D       E +  +  P S    Y   KR+ + L R ++   G +
Sbjct: 109 GVRKVVFASSAAVYGDLGGLTAGEEV--DARPKSF---YGLTKRVGEELCRFFS-GRGVV 162

Query: 465 FTSVIPCNVFGPYDNFSLESSHVIPALIRRMDDAMQKGDPTFTVMGSGKPLRQFIYSLDL 644
             ++   NV+G Y         VI    RR+      G P   V G G   R F+Y  D+
Sbjct: 163 CVALRIFNVYGEYSRRG-----VIYEFARRV----LSGLPV-KVYGDGNQTRDFVYVGDV 212

Query: 645 ARA 653
           ARA
Sbjct: 213 ARA 215


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 754,881,226
Number of Sequences: 1657284
Number of extensions: 16020480
Number of successful extensions: 36917
Number of sequences better than 10.0: 243
Number of HSP's better than 10.0 without gapping: 35556
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 36789
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 57851245060
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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