BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= epV31373 (704 letters) Database: human 237,096 sequences; 76,859,062 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value X04412-1|CAA28000.1| 782|Homo sapiens plasma gelsolin protein. 219 6e-57 BC026033-1|AAH26033.1| 782|Homo sapiens gelsolin (amyloidosis, ... 219 6e-57 AL513122-6|CAM20459.1| 731|Homo sapiens gelsolin (amyloidosis, ... 219 6e-57 AL513122-5|CAI14415.1| 260|Homo sapiens gelsolin (amyloidosis, ... 219 6e-57 AL513122-3|CAI14413.1| 782|Homo sapiens gelsolin (amyloidosis, ... 219 6e-57 AL513122-4|CAI14414.1| 228|Homo sapiens gelsolin (amyloidosis, ... 218 2e-56 AF276507-1|AAK60494.1| 715|Homo sapiens scinderin protein. 200 3e-51 AC005281-1|AAD15423.1| 527|Homo sapiens WUGSC:H_DJ0722F20.1 pro... 200 3e-51 AB067492-1|BAB67798.1| 626|Homo sapiens KIAA1905 protein protein. 200 3e-51 BC021090-1|AAH21090.1| 715|Homo sapiens SCIN protein protein. 200 4e-51 AK075123-1|BAC11416.1| 715|Homo sapiens protein ( Homo sapiens ... 199 7e-51 AF041449-1|AAC25051.1| 819|Homo sapiens advillin protein. 192 8e-49 X12901-1|CAA31386.1| 827|Homo sapiens protein ( Human mRNA for ... 182 1e-45 BC017303-1|AAH17303.1| 421|Homo sapiens VIL1 protein protein. 182 1e-45 AK223398-1|BAD97118.1| 827|Homo sapiens villin 1 variant protein. 182 1e-45 BC111730-1|AAI11731.1| 812|Homo sapiens AVIL protein protein. 179 1e-44 M94345-1|AAA59570.1| 348|Homo sapiens macrophage capping protei... 164 2e-40 BC014549-1|AAH14549.1| 348|Homo sapiens capping protein (actin ... 164 2e-40 BC000728-1|AAH00728.1| 348|Homo sapiens capping protein (actin ... 164 2e-40 AC062037-3|AAY24128.1| 348|Homo sapiens unknown protein. 164 2e-40 U12026-1|AAA92670.1| 172|Homo sapiens Cap-G protein. 133 7e-31 U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein. 125 2e-28 U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog prot... 125 2e-28 BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog (D... 125 2e-28 AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog va... 125 2e-28 AL513122-7|CAI14416.1| 485|Homo sapiens gelsolin (amyloidosis, ... 92 2e-18 AK075198-1|BAC11465.1| 396|Homo sapiens protein ( Homo sapiens ... 81 4e-15 AK027778-1|BAB55361.1| 468|Homo sapiens protein ( Homo sapiens ... 81 4e-15 BC075797-1|AAH75797.1| 85|Homo sapiens Unknown (protein for MG... 73 1e-12 X07066-1|CAA30102.1| 69|Homo sapiens protein ( Human gene for ... 71 3e-12 D88154-1|BAA21668.1| 686|Homo sapiens villin-like protein protein. 62 2e-09 BC004300-1|AAH04300.1| 672|Homo sapiens VILL protein protein. 62 2e-09 BC000243-1|AAH00243.1| 686|Homo sapiens VILL protein protein. 62 2e-09 AL160060-2|CAH71300.1| 2214|Homo sapiens supervillin protein. 58 2e-08 AL158167-3|CAI15237.1| 2214|Homo sapiens supervillin protein. 58 2e-08 AF109135-1|AAD14682.1| 2214|Homo sapiens archvillin protein. 58 2e-08 AL160060-1|CAH71301.1| 1788|Homo sapiens supervillin protein. 58 2e-08 AL158167-2|CAI15236.1| 1788|Homo sapiens supervillin protein. 58 2e-08 AF051851-1|AAC64696.1| 1788|Homo sapiens supervillin protein. 58 2e-08 AF051850-1|AAC64695.1| 1788|Homo sapiens supervillin protein. 58 2e-08 BC017491-1|AAH17491.1| 285|Homo sapiens Similar to gelsolin (am... 55 3e-07 AK092426-1|BAC03887.1| 258|Homo sapiens protein ( Homo sapiens ... 36 0.19 BC117319-1|AAI17320.1| 257|Homo sapiens TPRXL protein protein. 33 0.99 AL513122-9|CAI14417.1| 207|Homo sapiens gelsolin (amyloidosis, ... 32 1.7 BC106877-1|AAI06878.1| 663|Homo sapiens chromosome 1 open readi... 32 2.3 AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ ... 32 2.3 AK001763-1|BAA91892.1| 663|Homo sapiens protein ( Homo sapiens ... 32 2.3 D31661-1|BAA06506.1| 981|Homo sapiens tyrosine kinase precursor... 30 7.0 >X04412-1|CAA28000.1| 782|Homo sapiens plasma gelsolin protein. Length = 782 Score = 219 bits (536), Expect = 6e-57 Identities = 106/220 (48%), Positives = 145/220 (65%), Gaps = 1/220 (0%) Frame = +1 Query: 34 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 210 H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++ L +D+H+W Sbjct: 56 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 115 Query: 211 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHAS 390 LG+ SQDE+GAAAI TV LDD G AVQHREVQ +ES FL YF ++Y KGG AS Sbjct: 116 LGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVAS 174 Query: 391 GFSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKG 570 GF HV NE +RLFQ+KG+R VR +V ++ES NNGDCFILD+ + I + G + Sbjct: 175 GFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNR 234 Query: 571 VERMKAITVANQIKDQDHNGRADIEVVDSEAHDGNLRQVL 690 ER+KA V+ I+D + +GRA + V + + QVL Sbjct: 235 YERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVL 274 Score = 91.9 bits (218), Expect = 2e-18 Identities = 66/186 (35%), Positives = 91/186 (48%), Gaps = 4/186 (2%) Frame = +1 Query: 73 EIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAAA 252 +IWRIE V V +G FY GDSYI+L R I+ W G++++QDE A+A Sbjct: 448 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASA 507 Query: 253 ILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYLKGGHASGFSHVTINEGTE 426 ILT L DE+ G+ VQ R VQ E + F P I Y KGG S T T Sbjct: 508 ILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIY-KGG-TSREGGQTAPAST- 563 Query: 427 KRLFQIKGKR--NVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVA 600 RLFQ++ R +V P +LN+ D F+L +++VG A E+ A + Sbjct: 564 -RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELL 622 Query: 601 NQIKDQ 618 ++ Q Sbjct: 623 RVLRAQ 628 Score = 41.9 bits (94), Expect = 0.002 Identities = 42/160 (26%), Positives = 72/160 (45%), Gaps = 8/160 (5%) Frame = +1 Query: 196 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLK 375 +IH W GS +++ E A ++ + D + G A H + E + L+ P L Sbjct: 223 NIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPK-PALP 281 Query: 376 GGHASGFSHVTINEGTEKRLFQIK---GKRNVRVKQVKPTFE--SLNNGDCFILD--VDH 534 G N K L+++ G +V + + F +L + DCFILD D Sbjct: 282 AGTEDTAKEDAANRKLAK-LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDG 340 Query: 535 QIFVFVGEKAKGVERMKAI-TVANQIKDQDHNGRADIEVV 651 +IFV+ G++A ER A+ T ++ I D+ + + V+ Sbjct: 341 KIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVL 380 Score = 32.3 bits (70), Expect = 1.7 Identities = 16/48 (33%), Positives = 27/48 (56%) Frame = +1 Query: 490 ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 633 E L D +LD Q+FV+VG+ ++ E+ +A+T A + + D R Sbjct: 691 EDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANR 738 >BC026033-1|AAH26033.1| 782|Homo sapiens gelsolin (amyloidosis, Finnish type) protein. Length = 782 Score = 219 bits (536), Expect = 6e-57 Identities = 106/220 (48%), Positives = 145/220 (65%), Gaps = 1/220 (0%) Frame = +1 Query: 34 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 210 H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++ L +D+H+W Sbjct: 56 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 115 Query: 211 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHAS 390 LG+ SQDE+GAAAI TV LDD G AVQHREVQ +ES FL YF ++Y KGG AS Sbjct: 116 LGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVAS 174 Query: 391 GFSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKG 570 GF HV NE +RLFQ+KG+R VR +V ++ES NNGDCFILD+ + I + G + Sbjct: 175 GFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNR 234 Query: 571 VERMKAITVANQIKDQDHNGRADIEVVDSEAHDGNLRQVL 690 ER+KA V+ I+D + +GRA + V + + QVL Sbjct: 235 YERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVL 274 Score = 91.9 bits (218), Expect = 2e-18 Identities = 66/186 (35%), Positives = 91/186 (48%), Gaps = 4/186 (2%) Frame = +1 Query: 73 EIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAAA 252 +IWRIE V V +G FY GDSYI+L R I+ W G++++QDE A+A Sbjct: 448 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASA 507 Query: 253 ILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYLKGGHASGFSHVTINEGTE 426 ILT L DE+ G+ VQ R VQ E + F P I Y KGG S T T Sbjct: 508 ILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIY-KGG-TSREGGQTAPAST- 563 Query: 427 KRLFQIKGKR--NVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVA 600 RLFQ++ R +V P +LN+ D F+L +++VG A E+ A + Sbjct: 564 -RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELL 622 Query: 601 NQIKDQ 618 ++ Q Sbjct: 623 RVLRAQ 628 Score = 41.9 bits (94), Expect = 0.002 Identities = 42/160 (26%), Positives = 72/160 (45%), Gaps = 8/160 (5%) Frame = +1 Query: 196 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLK 375 +IH W GS +++ E A ++ + D + G A H + E + L+ P L Sbjct: 223 NIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPK-PALP 281 Query: 376 GGHASGFSHVTINEGTEKRLFQIK---GKRNVRVKQVKPTFE--SLNNGDCFILD--VDH 534 G N K L+++ G +V + + F +L + DCFILD D Sbjct: 282 AGTEDTAKEDAANRKLAK-LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDG 340 Query: 535 QIFVFVGEKAKGVERMKAI-TVANQIKDQDHNGRADIEVV 651 +IFV+ G++A ER A+ T ++ I D+ + + V+ Sbjct: 341 KIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVL 380 Score = 32.3 bits (70), Expect = 1.7 Identities = 16/48 (33%), Positives = 27/48 (56%) Frame = +1 Query: 490 ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 633 E L D +LD Q+FV+VG+ ++ E+ +A+T A + + D R Sbjct: 691 EDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANR 738 >AL513122-6|CAM20459.1| 731|Homo sapiens gelsolin (amyloidosis, Finnish type) protein. Length = 731 Score = 219 bits (536), Expect = 6e-57 Identities = 106/220 (48%), Positives = 145/220 (65%), Gaps = 1/220 (0%) Frame = +1 Query: 34 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 210 H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++ L +D+H+W Sbjct: 5 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 64 Query: 211 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHAS 390 LG+ SQDE+GAAAI TV LDD G AVQHREVQ +ES FL YF ++Y KGG AS Sbjct: 65 LGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVAS 123 Query: 391 GFSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKG 570 GF HV NE +RLFQ+KG+R VR +V ++ES NNGDCFILD+ + I + G + Sbjct: 124 GFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNR 183 Query: 571 VERMKAITVANQIKDQDHNGRADIEVVDSEAHDGNLRQVL 690 ER+KA V+ I+D + +GRA + V + + QVL Sbjct: 184 YERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVL 223 Score = 91.9 bits (218), Expect = 2e-18 Identities = 66/186 (35%), Positives = 91/186 (48%), Gaps = 4/186 (2%) Frame = +1 Query: 73 EIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAAA 252 +IWRIE V V +G FY GDSYI+L R I+ W G++++QDE A+A Sbjct: 397 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASA 456 Query: 253 ILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYLKGGHASGFSHVTINEGTE 426 ILT L DE+ G+ VQ R VQ E + F P I Y KGG S T T Sbjct: 457 ILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIY-KGG-TSREGGQTAPAST- 512 Query: 427 KRLFQIKGKR--NVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVA 600 RLFQ++ R +V P +LN+ D F+L +++VG A E+ A + Sbjct: 513 -RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELL 571 Query: 601 NQIKDQ 618 ++ Q Sbjct: 572 RVLRAQ 577 Score = 41.9 bits (94), Expect = 0.002 Identities = 42/160 (26%), Positives = 72/160 (45%), Gaps = 8/160 (5%) Frame = +1 Query: 196 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLK 375 +IH W GS +++ E A ++ + D + G A H + E + L+ P L Sbjct: 172 NIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPK-PALP 230 Query: 376 GGHASGFSHVTINEGTEKRLFQIK---GKRNVRVKQVKPTFE--SLNNGDCFILD--VDH 534 G N K L+++ G +V + + F +L + DCFILD D Sbjct: 231 AGTEDTAKEDAANRKLAK-LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDG 289 Query: 535 QIFVFVGEKAKGVERMKAI-TVANQIKDQDHNGRADIEVV 651 +IFV+ G++A ER A+ T ++ I D+ + + V+ Sbjct: 290 KIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVL 329 Score = 32.3 bits (70), Expect = 1.7 Identities = 16/48 (33%), Positives = 27/48 (56%) Frame = +1 Query: 490 ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 633 E L D +LD Q+FV+VG+ ++ E+ +A+T A + + D R Sbjct: 640 EDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANR 687 >AL513122-5|CAI14415.1| 260|Homo sapiens gelsolin (amyloidosis, Finnish type) protein. Length = 260 Score = 219 bits (536), Expect = 6e-57 Identities = 106/220 (48%), Positives = 145/220 (65%), Gaps = 1/220 (0%) Frame = +1 Query: 34 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 210 H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++ L +D+H+W Sbjct: 5 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 64 Query: 211 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHAS 390 LG+ SQDE+GAAAI TV LDD G AVQHREVQ +ES FL YF ++Y KGG AS Sbjct: 65 LGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVAS 123 Query: 391 GFSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKG 570 GF HV NE +RLFQ+KG+R VR +V ++ES NNGDCFILD+ + I + G + Sbjct: 124 GFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNR 183 Query: 571 VERMKAITVANQIKDQDHNGRADIEVVDSEAHDGNLRQVL 690 ER+KA V+ I+D + +GRA + V + + QVL Sbjct: 184 YERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVL 223 >AL513122-3|CAI14413.1| 782|Homo sapiens gelsolin (amyloidosis, Finnish type) protein. Length = 782 Score = 219 bits (536), Expect = 6e-57 Identities = 106/220 (48%), Positives = 145/220 (65%), Gaps = 1/220 (0%) Frame = +1 Query: 34 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 210 H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++ L +D+H+W Sbjct: 56 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 115 Query: 211 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHAS 390 LG+ SQDE+GAAAI TV LDD G AVQHREVQ +ES FL YF ++Y KGG AS Sbjct: 116 LGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVAS 174 Query: 391 GFSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKG 570 GF HV NE +RLFQ+KG+R VR +V ++ES NNGDCFILD+ + I + G + Sbjct: 175 GFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNR 234 Query: 571 VERMKAITVANQIKDQDHNGRADIEVVDSEAHDGNLRQVL 690 ER+KA V+ I+D + +GRA + V + + QVL Sbjct: 235 YERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVL 274 Score = 91.9 bits (218), Expect = 2e-18 Identities = 66/186 (35%), Positives = 91/186 (48%), Gaps = 4/186 (2%) Frame = +1 Query: 73 EIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAAA 252 +IWRIE V V +G FY GDSYI+L R I+ W G++++QDE A+A Sbjct: 448 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASA 507 Query: 253 ILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYLKGGHASGFSHVTINEGTE 426 ILT L DE+ G+ VQ R VQ E + F P I Y KGG S T T Sbjct: 508 ILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIY-KGG-TSREGGQTAPAST- 563 Query: 427 KRLFQIKGKR--NVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVA 600 RLFQ++ R +V P +LN+ D F+L +++VG A E+ A + Sbjct: 564 -RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELL 622 Query: 601 NQIKDQ 618 ++ Q Sbjct: 623 RVLRAQ 628 Score = 41.9 bits (94), Expect = 0.002 Identities = 42/160 (26%), Positives = 72/160 (45%), Gaps = 8/160 (5%) Frame = +1 Query: 196 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLK 375 +IH W GS +++ E A ++ + D + G A H + E + L+ P L Sbjct: 223 NIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPK-PALP 281 Query: 376 GGHASGFSHVTINEGTEKRLFQIK---GKRNVRVKQVKPTFE--SLNNGDCFILD--VDH 534 G N K L+++ G +V + + F +L + DCFILD D Sbjct: 282 AGTEDTAKEDAANRKLAK-LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDG 340 Query: 535 QIFVFVGEKAKGVERMKAI-TVANQIKDQDHNGRADIEVV 651 +IFV+ G++A ER A+ T ++ I D+ + + V+ Sbjct: 341 KIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVL 380 Score = 32.3 bits (70), Expect = 1.7 Identities = 16/48 (33%), Positives = 27/48 (56%) Frame = +1 Query: 490 ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 633 E L D +LD Q+FV+VG+ ++ E+ +A+T A + + D R Sbjct: 691 EDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANR 738 >AL513122-4|CAI14414.1| 228|Homo sapiens gelsolin (amyloidosis, Finnish type) protein. Length = 228 Score = 218 bits (532), Expect = 2e-56 Identities = 105/215 (48%), Positives = 142/215 (66%), Gaps = 1/215 (0%) Frame = +1 Query: 7 CTRPKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD- 183 C M H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++ Sbjct: 7 CFPNSMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNG 66 Query: 184 RLTWDIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAI 363 L +D+H+WLG+ SQDE+GAAAI TV LDD G AVQHREVQ +ES FL YF + Sbjct: 67 NLQYDLHYWLGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYFKSGL 125 Query: 364 RYLKGGHASGFSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIF 543 +Y KGG ASGF HV NE +RLFQ+KG+R VR +V ++ES NNGDCFILD+ + I Sbjct: 126 KYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIH 185 Query: 544 VFVGEKAKGVERMKAITVANQIKDQDHNGRADIEV 648 + G + ER+KA V+ I+D + +GRA + V Sbjct: 186 QWCGSNSNRYERLKATQVSKGIRDNERSGRARVHV 220 >AF276507-1|AAK60494.1| 715|Homo sapiens scinderin protein. Length = 715 Score = 200 bits (489), Expect = 3e-51 Identities = 97/219 (44%), Positives = 139/219 (63%) Frame = +1 Query: 34 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 213 H+ FA AG++ GL++WRIE E V VP++ G FY GD+Y+VL+T T+ +HFWL Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWL 66 Query: 214 GSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASG 393 G SQDE+ AAAI TV +DD G VQ+RE+Q YES +F+ YF ++Y GG ASG Sbjct: 67 GKECSQDESTAAAIFTVQMDD-YLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125 Query: 394 FSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGV 573 +HV N+ T KRL +KG+R VR +V +++S N GDCFI+D+ +I+ + G Sbjct: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185 Query: 574 ERMKAITVANQIKDQDHNGRADIEVVDSEAHDGNLRQVL 690 ER+KA VA I+ + GR+++ VV+ + L +VL Sbjct: 186 ERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVL 224 Score = 81.4 bits (192), Expect = 3e-15 Identities = 68/206 (33%), Positives = 97/206 (47%), Gaps = 7/206 (3%) Frame = +1 Query: 16 PKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTW 195 P+M H D K +EIWR+EN + V + +G FY GD YI+L T + ++ Sbjct: 382 PQMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI-- 436 Query: 196 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRY 369 I+ W G+ ++DE +A LTV L D G AVQ R Q E L F P I Y Sbjct: 437 -IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQDKEPVHLLSLFKDKPLIIY 494 Query: 370 LKGGHASGFSHVTINEGTEKRLFQIKGKRNV----RVKQVKPTFESLNNGDCFILDVDHQ 537 G G RLFQ+ +RN+ R+ +V SLN+ D F+L + Sbjct: 495 KNGTSKKGGQ----APAPPTRLFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLSQN 548 Query: 538 I-FVFVGEKAKGVERMKAITVANQIK 612 +++VG+ A E A VA+ +K Sbjct: 549 SGYIWVGKGASQEEEKGAEYVASVLK 574 Score = 35.1 bits (77), Expect = 0.25 Identities = 16/50 (32%), Positives = 28/50 (56%) Frame = +1 Query: 484 TFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 633 T + L D +LD QIF+++G+ A VE+ +++ A + D +GR Sbjct: 636 TQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGR 685 >AC005281-1|AAD15423.1| 527|Homo sapiens WUGSC:H_DJ0722F20.1 protein. Length = 527 Score = 200 bits (489), Expect = 3e-51 Identities = 97/219 (44%), Positives = 139/219 (63%) Frame = +1 Query: 34 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 213 H+ FA AG++ GL++WRIE E V VP++ G FY GD+Y+VL+T T+ +HFWL Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWL 66 Query: 214 GSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASG 393 G SQDE+ AAAI TV +DD G VQ+RE+Q YES +F+ YF ++Y GG ASG Sbjct: 67 GKECSQDESTAAAIFTVQMDD-YLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125 Query: 394 FSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGV 573 +HV N+ T KRL +KG+R VR +V +++S N GDCFI+D+ +I+ + G Sbjct: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185 Query: 574 ERMKAITVANQIKDQDHNGRADIEVVDSEAHDGNLRQVL 690 ER+KA VA I+ + GR+++ VV+ + L +VL Sbjct: 186 ERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVL 224 Score = 66.1 bits (154), Expect = 1e-10 Identities = 46/128 (35%), Positives = 61/128 (47%), Gaps = 2/128 (1%) Frame = +1 Query: 16 PKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTW 195 P+M H D K +EIWR+EN + V + +G FY GD YI+L T + ++ Sbjct: 382 PQMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI-- 436 Query: 196 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRY 369 I+ W G+ ++DE +A LTV L D G AVQ R Q E L F P I Y Sbjct: 437 -IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIY 494 Query: 370 LKGGHASG 393 G G Sbjct: 495 KNGTSKKG 502 >AB067492-1|BAB67798.1| 626|Homo sapiens KIAA1905 protein protein. Length = 626 Score = 200 bits (489), Expect = 3e-51 Identities = 97/219 (44%), Positives = 139/219 (63%) Frame = +1 Query: 34 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 213 H+ FA AG++ GL++WRIE E V VP++ G FY GD+Y+VL+T T+ +HFWL Sbjct: 53 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWL 112 Query: 214 GSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASG 393 G SQDE+ AAAI TV +DD G VQ+RE+Q YES +F+ YF ++Y GG ASG Sbjct: 113 GKECSQDESTAAAIFTVQMDD-YLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 171 Query: 394 FSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGV 573 +HV N+ T KRL +KG+R VR +V +++S N GDCFI+D+ +I+ + G Sbjct: 172 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 231 Query: 574 ERMKAITVANQIKDQDHNGRADIEVVDSEAHDGNLRQVL 690 ER+KA VA I+ + GR+++ VV+ + L +VL Sbjct: 232 ERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVL 270 Score = 66.1 bits (154), Expect = 1e-10 Identities = 46/128 (35%), Positives = 61/128 (47%), Gaps = 2/128 (1%) Frame = +1 Query: 16 PKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTW 195 P+M H D K +EIWR+EN + V + +G FY GD YI+L T + ++ Sbjct: 428 PQMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI-- 482 Query: 196 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRY 369 I+ W G+ ++DE +A LTV L D G AVQ R Q E L F P I Y Sbjct: 483 -IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIY 540 Query: 370 LKGGHASG 393 G G Sbjct: 541 KNGTSKKG 548 >BC021090-1|AAH21090.1| 715|Homo sapiens SCIN protein protein. Length = 715 Score = 200 bits (488), Expect = 4e-51 Identities = 97/219 (44%), Positives = 139/219 (63%) Frame = +1 Query: 34 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 213 H+ FA AG++ GL++WRIE E V VP++ G FY GD+Y+VL+T T+ +HFWL Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYRLHFWL 66 Query: 214 GSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASG 393 G SQDE+ AAAI TV +DD G VQ+RE+Q YES +F+ YF ++Y GG ASG Sbjct: 67 GKECSQDESTAAAIFTVQMDD-YLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125 Query: 394 FSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGV 573 +HV N+ T KRL +KG+R VR +V +++S N GDCFI+D+ +I+ + G Sbjct: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185 Query: 574 ERMKAITVANQIKDQDHNGRADIEVVDSEAHDGNLRQVL 690 ER+KA VA I+ + GR+++ VV+ + L +VL Sbjct: 186 ERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVL 224 Score = 81.0 bits (191), Expect = 4e-15 Identities = 68/206 (33%), Positives = 98/206 (47%), Gaps = 7/206 (3%) Frame = +1 Query: 16 PKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTW 195 P+M H D K +EIWR+EN + V + +G FY GD YI+L T + ++ Sbjct: 382 PQMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI-- 436 Query: 196 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRY 369 I+ W G+ ++DE +A LTV L D G AVQ R Q E L F P I Y Sbjct: 437 -IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIY 494 Query: 370 LKGGHASGFSHVTINEGTEKRLFQIKGKRNV----RVKQVKPTFESLNNGDCFILDV-DH 534 G G RLFQ+ +RN+ R+ +V SLN+ D F+L + + Sbjct: 495 KNGTSKKGGQ----APAPPTRLFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLPQN 548 Query: 535 QIFVFVGEKAKGVERMKAITVANQIK 612 +++VG+ A E A VA+ +K Sbjct: 549 SGYIWVGKGASQEEEKGAEYVASVLK 574 Score = 35.1 bits (77), Expect = 0.25 Identities = 16/50 (32%), Positives = 28/50 (56%) Frame = +1 Query: 484 TFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 633 T + L D +LD QIF+++G+ A VE+ +++ A + D +GR Sbjct: 636 TQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGR 685 >AK075123-1|BAC11416.1| 715|Homo sapiens protein ( Homo sapiens cDNA FLJ90642 fis, clone PLACE1004078, highly similar to Bovine mRNA for adseverin. ). Length = 715 Score = 199 bits (486), Expect = 7e-51 Identities = 96/219 (43%), Positives = 139/219 (63%) Frame = +1 Query: 34 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 213 H+ FA AG++ GL++WRIE E V VP++ G FY GD+Y++L+T T+ +HFWL Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLMLHTAKTSRGFTYHLHFWL 66 Query: 214 GSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASG 393 G SQDE+ AAAI TV +DD G VQ+RE+Q YES +F+ YF ++Y GG ASG Sbjct: 67 GKECSQDESTAAAIFTVQMDD-YLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125 Query: 394 FSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGV 573 +HV N+ T KRL +KG+R VR +V +++S N GDCFI+D+ +I+ + G Sbjct: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185 Query: 574 ERMKAITVANQIKDQDHNGRADIEVVDSEAHDGNLRQVL 690 ER+KA VA I+ + GR+++ VV+ + L +VL Sbjct: 186 ERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVL 224 Score = 81.0 bits (191), Expect = 4e-15 Identities = 68/206 (33%), Positives = 98/206 (47%), Gaps = 7/206 (3%) Frame = +1 Query: 16 PKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTW 195 P+M H D K +EIWR+EN + V + +G FY GD YI+L T + ++ Sbjct: 382 PQMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI-- 436 Query: 196 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRY 369 I+ W G+ ++DE +A LTV L D G AVQ R Q E L F P I Y Sbjct: 437 -IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIY 494 Query: 370 LKGGHASGFSHVTINEGTEKRLFQIKGKRNV----RVKQVKPTFESLNNGDCFILDV-DH 534 G G RLFQ+ +RN+ R+ +V SLN+ D F+L + + Sbjct: 495 KNGTSKKGGQ----APAPPTRLFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLPQN 548 Query: 535 QIFVFVGEKAKGVERMKAITVANQIK 612 +++VG+ A E A VA+ +K Sbjct: 549 SGYIWVGKGASQEEEKGAEYVASVLK 574 Score = 35.1 bits (77), Expect = 0.25 Identities = 16/50 (32%), Positives = 28/50 (56%) Frame = +1 Query: 484 TFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 633 T + L D +LD QIF+++G+ A VE+ +++ A + D +GR Sbjct: 636 TQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGR 685 >AF041449-1|AAC25051.1| 819|Homo sapiens advillin protein. Length = 819 Score = 192 bits (469), Expect = 8e-49 Identities = 99/220 (45%), Positives = 132/220 (60%), Gaps = 2/220 (0%) Frame = +1 Query: 40 AFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGS 219 AF PG+ +WRIE E VP + G FY GD Y++L+T L+ DIHFW+G Sbjct: 6 AFRAVDNDPGIIVWRIEKMELALVPVSAHGNFYEGDCYVILSTRRVASLLSQDIHFWIGK 65 Query: 220 RTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFS 399 +SQDE AAI T LDD GS VQHREVQY+ES F YF I Y +GG ASG Sbjct: 66 DSSQDEQSCAAIYTTQLDD-YLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMK 124 Query: 400 HVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVER 579 HV N KRL +KGKRN+R +V+ +++S N GD F+LD+ I + G ++ ER Sbjct: 125 HVETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGER 184 Query: 580 MKAITVANQIKDQDHNGRADIEVV--DSEAHDGNLRQVLR 693 +KA+ +A I+D++ GRA+I V+ D EA L +VL+ Sbjct: 185 LKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQ 224 Score = 96.7 bits (230), Expect = 7e-20 Identities = 67/212 (31%), Positives = 100/212 (47%), Gaps = 2/212 (0%) Frame = +1 Query: 10 TRPKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRL 189 T+P++ + D K +E+WRIEN E V V +G FY GD Y+VL T + Sbjct: 379 TKPEVAAQERMVDDGNGK--VEVWRIENLELVPVEYQWYGFFYGGDCYLVLYTYEVNGKP 436 Query: 190 TWDIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRY 369 ++ W SQDE A+A V + D QF G+AVQ R E + F+ F + Sbjct: 437 HHILYIWQDRHASQDELAASAYQAVEV-DRQFDGAAVQVRVRMGTEPRHFMAIFKGKLVI 495 Query: 370 LKGGHASGFSHVTINEGTEKRLFQIKG--KRNVRVKQVKPTFESLNNGDCFILDVDHQIF 543 +GG + RLFQI G K N + +V SLN+ D F+L + + Sbjct: 496 FEGGTS---RKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAEHY 552 Query: 544 VFVGEKAKGVERMKAITVANQIKDQDHNGRAD 639 ++ G+ + G ER A +A+ + D N A+ Sbjct: 553 LWYGKGSSGDERAMAKELASLLCDGSENTVAE 584 Score = 35.5 bits (78), Expect = 0.19 Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 2/72 (2%) Frame = +1 Query: 424 EKRLFQIKGKRN--VRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITV 597 + RLF+ K V + T + LN D +LD Q+F+++G +A E+ A+ Sbjct: 615 QSRLFECSNKTGQFVVTEITDFTQDDLNPTDVMLLDTWDQVFLWIGAEANATEKESALAT 674 Query: 598 ANQIKDQDHNGR 633 A Q +GR Sbjct: 675 AQQYLHTHPSGR 686 Score = 33.5 bits (73), Expect = 0.75 Identities = 20/68 (29%), Positives = 37/68 (54%), Gaps = 2/68 (2%) Frame = +1 Query: 496 LNNGDCFILDVD-HQIFVFVGEKAKGVERMKAITVA-NQIKDQDHNGRADIEVVDSEAHD 669 LN+ DC+ILD +I+V+ G+ A E+ A++ A IK + + ++E V+ A Sbjct: 277 LNHDDCYILDQSGTKIYVWKGKGATKAEKQAAMSKALGFIKMKSYPSSTNVETVNDGAES 336 Query: 670 GNLRQVLR 693 +Q+ + Sbjct: 337 AMFKQLFQ 344 >X12901-1|CAA31386.1| 827|Homo sapiens protein ( Human mRNA for villin. ). Length = 827 Score = 182 bits (442), Expect = 1e-45 Identities = 90/199 (45%), Positives = 125/199 (62%) Frame = +1 Query: 64 PGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAG 243 PGL+IWRIE + V VP + FG F+ GD YI+L L++DIH+W+G +S DE G Sbjct: 17 PGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASSLSYDIHYWIGQDSSLDEQG 76 Query: 244 AAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFSHVTINEGT 423 AAAI T +DD +G AVQHREVQ ES+ F YF + KGG ASG HV N Sbjct: 77 AAAIYTTQMDDF-LKGRAVQHREVQGNESEAFRGYFKQGLVIRKGGVASGMKHVETNSYD 135 Query: 424 EKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVAN 603 +RL +KGKRNV +V+ +++S N GD F+LD+ I + G ++ +ER++ +T+A Sbjct: 136 VQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAK 195 Query: 604 QIKDQDHNGRADIEVVDSE 660 +I+DQ+ GR + VVD E Sbjct: 196 EIRDQERGGRTYVGVVDGE 214 Score = 87.0 bits (206), Expect = 6e-17 Identities = 57/182 (31%), Positives = 89/182 (48%), Gaps = 2/182 (1%) Frame = +1 Query: 70 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAA 249 +++WRIEN E V V G FY GD Y++L T ++ + ++ W GS+ SQDE A+ Sbjct: 400 VQVWRIENLELVPVDSKWLGHFYGGDCYLLLYTYLIGEKQHYLLYVWQGSQASQDEITAS 459 Query: 250 AILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFSHVTINEGTEK 429 A V L D+++ G VQ R E + F + +GG + + + G Sbjct: 460 AYQAVIL-DQKYNGEPVQIRVPMGKEPPHLMSIFKGRMVVYQGGTSRTNN---LETGPST 515 Query: 430 RLFQIK--GKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVAN 603 RLFQ++ G N + +V LN+ D F+L +++ G+ G ER A VA+ Sbjct: 516 RLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKTQSCCYLWCGKGCSGDEREMAKMVAD 575 Query: 604 QI 609 I Sbjct: 576 TI 577 Score = 36.3 bits (80), Expect = 0.11 Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 2/70 (2%) Frame = +1 Query: 430 RLFQIKGKRNVRVKQVKPTF--ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVAN 603 RLF+ K + P F + L D F+LDV Q+F ++G+ A E+ A T A Sbjct: 620 RLFECSNKTGRFLATEIPDFNQDDLEEDDVFLLDVWDQVFFWIGKHANEEEKKAAATTAQ 679 Query: 604 QIKDQDHNGR 633 + +GR Sbjct: 680 EYLKTHPSGR 689 >BC017303-1|AAH17303.1| 421|Homo sapiens VIL1 protein protein. Length = 421 Score = 182 bits (442), Expect = 1e-45 Identities = 90/199 (45%), Positives = 125/199 (62%) Frame = +1 Query: 64 PGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAG 243 PGL+IWRIE + V VP + FG F+ GD YI+L L++DIH+W+G +S DE G Sbjct: 17 PGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASSLSYDIHYWIGQDSSLDEQG 76 Query: 244 AAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFSHVTINEGT 423 AAAI T +DD +G AVQHREVQ ES+ F YF + KGG ASG HV N Sbjct: 77 AAAIYTTQMDDF-LKGRAVQHREVQGNESEAFRGYFKQGLVIRKGGVASGMKHVETNSYD 135 Query: 424 EKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVAN 603 +RL +KGKRNV +V+ +++S N GD F+LD+ I + G ++ +ER++ +T+A Sbjct: 136 VQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAK 195 Query: 604 QIKDQDHNGRADIEVVDSE 660 +I+DQ+ GR + VVD E Sbjct: 196 EIRDQERGGRTYVGVVDGE 214 >AK223398-1|BAD97118.1| 827|Homo sapiens villin 1 variant protein. Length = 827 Score = 182 bits (442), Expect = 1e-45 Identities = 90/199 (45%), Positives = 125/199 (62%) Frame = +1 Query: 64 PGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAG 243 PGL+IWRIE + V VP + FG F+ GD YI+L L++DIH+W+G +S DE G Sbjct: 17 PGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASSLSYDIHYWIGQDSSLDEQG 76 Query: 244 AAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFSHVTINEGT 423 AAAI T +DD +G AVQHREVQ ES+ F YF + KGG ASG HV N Sbjct: 77 AAAIYTTQMDDF-LKGRAVQHREVQGNESEAFRGYFKQGLVIRKGGVASGMKHVETNSYD 135 Query: 424 EKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVAN 603 +RL +KGKRNV +V+ +++S N GD F+LD+ I + G ++ +ER++ +T+A Sbjct: 136 VQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAK 195 Query: 604 QIKDQDHNGRADIEVVDSE 660 +I+DQ+ GR + VVD E Sbjct: 196 EIRDQERGGRTYVGVVDGE 214 Score = 87.0 bits (206), Expect = 6e-17 Identities = 57/182 (31%), Positives = 89/182 (48%), Gaps = 2/182 (1%) Frame = +1 Query: 70 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAA 249 +++WRIEN E V V G FY GD Y++L T ++ + ++ W GS+ SQDE A+ Sbjct: 400 VQVWRIENLELVPVDSKWLGHFYGGDCYLLLYTYLIGEKQHYLLYVWQGSQASQDEITAS 459 Query: 250 AILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFSHVTINEGTEK 429 A V L D+++ G VQ R E + F + +GG + + + G Sbjct: 460 AYQAVIL-DQKYNGEPVQIRVPMGKEPPHLMSIFKGRMVVYQGGTSRTNN---LETGPST 515 Query: 430 RLFQIK--GKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVAN 603 RLFQ++ G N + +V LN+ D F+L +++ G+ G ER A VA+ Sbjct: 516 RLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKTQSCCYLWCGKGCSGDEREMAKMVAD 575 Query: 604 QI 609 I Sbjct: 576 TI 577 Score = 36.3 bits (80), Expect = 0.11 Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 2/70 (2%) Frame = +1 Query: 430 RLFQIKGKRNVRVKQVKPTF--ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVAN 603 RLF+ K + P F + L D F+LDV Q+F ++G+ A E+ A T A Sbjct: 620 RLFECSNKTGRFLATEIPDFNQDDLEEDDVFLLDVWDQVFFWIGKHANEEEKKAAATTAQ 679 Query: 604 QIKDQDHNGR 633 + +GR Sbjct: 680 EYLKTHPSGR 689 >BC111730-1|AAI11731.1| 812|Homo sapiens AVIL protein protein. Length = 812 Score = 179 bits (435), Expect = 1e-44 Identities = 95/218 (43%), Positives = 128/218 (58%), Gaps = 2/218 (0%) Frame = +1 Query: 46 ADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRT 225 + G +IW E E VP + G FY GD Y++L+T L+ DIHFW+G + Sbjct: 2 SSTGHPGSYKIWG-EKMELALVPVSAHGNFYEGDCYVILSTRRVASLLSQDIHFWIGKDS 60 Query: 226 SQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFSHV 405 SQDE AAI T LDD GS VQHREVQY+ES F YF I Y +GG ASG HV Sbjct: 61 SQDEQSCAAIYTTQLDD-YLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMKHV 119 Query: 406 TINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMK 585 N KRL +KGKRN+R +V+ +++S N GD F+LD+ I + G ++ ER+K Sbjct: 120 ETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERLK 179 Query: 586 AITVANQIKDQDHNGRADIEVV--DSEAHDGNLRQVLR 693 A+ +A I+D++ GRA+I V+ D EA L +VL+ Sbjct: 180 AMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQ 217 Score = 99.5 bits (237), Expect = 1e-20 Identities = 68/212 (32%), Positives = 101/212 (47%), Gaps = 2/212 (0%) Frame = +1 Query: 10 TRPKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRL 189 T+P++ + D K +E+WRIEN E V V +G FY GD Y+VL T + Sbjct: 372 TKPEVAAQERMVDDGNGK--VEVWRIENLELVPVEYQWYGFFYGGDCYLVLYTYEVNGKP 429 Query: 190 TWDIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRY 369 ++ W G SQDE A+A V + D QF G+AVQ R E + F+ F + Sbjct: 430 HHILYIWQGRHASQDELAASAYQAVEV-DRQFDGAAVQVRVRMGTEPRHFMAIFKGKLVI 488 Query: 370 LKGGHASGFSHVTINEGTEKRLFQIKG--KRNVRVKQVKPTFESLNNGDCFILDVDHQIF 543 +GG + RLFQI G K N + +V SLN+ D F+L + + Sbjct: 489 FEGGTS---RKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAEHY 545 Query: 544 VFVGEKAKGVERMKAITVANQIKDQDHNGRAD 639 ++ G+ + G ER A +A+ + D N A+ Sbjct: 546 LWYGKGSSGDERAMAKELASLLCDGSENTVAE 577 Score = 35.5 bits (78), Expect = 0.19 Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 2/72 (2%) Frame = +1 Query: 424 EKRLFQIKGKRN--VRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITV 597 + RLF+ K V + T + LN D +LD Q+F+++G +A E+ A+ Sbjct: 608 QSRLFECSNKTGQFVVTEITDFTQDDLNPTDVMLLDTWDQVFLWIGAEANATEKESALAT 667 Query: 598 ANQIKDQDHNGR 633 A Q +GR Sbjct: 668 AQQYLHTHPSGR 679 Score = 33.5 bits (73), Expect = 0.75 Identities = 20/68 (29%), Positives = 37/68 (54%), Gaps = 2/68 (2%) Frame = +1 Query: 496 LNNGDCFILDVD-HQIFVFVGEKAKGVERMKAITVA-NQIKDQDHNGRADIEVVDSEAHD 669 LN+ DC+ILD +I+V+ G+ A E+ A++ A IK + + ++E V+ A Sbjct: 270 LNHDDCYILDQSGTKIYVWKGKGATKAEKQAAMSKALGFIKMKSYPSSTNVETVNDGAES 329 Query: 670 GNLRQVLR 693 +Q+ + Sbjct: 330 AMFKQLFQ 337 >M94345-1|AAA59570.1| 348|Homo sapiens macrophage capping protein protein. Length = 348 Score = 164 bits (399), Expect = 2e-40 Identities = 84/224 (37%), Positives = 131/224 (58%), Gaps = 1/224 (0%) Frame = +1 Query: 22 MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 201 +P+ F + + PGL +WR+E +PV V + G+F+SGDSY+VL+ ++ + Sbjct: 5 IPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEE---VSHL 61 Query: 202 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 381 H W+G ++S+DE GA A+L V+L+ + VQHREVQ ES F+ YF ++Y +GG Sbjct: 62 HLWIGQQSSRDEQGACAVLAVHLNTLLGE-RPVQHREVQGNESDLFMSYFPRGLKYQEGG 120 Query: 382 HASGFSHVTINEGTE-KRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGE 558 S F + K+L+Q+KGK+N+R + ++S N GDCFILD+ IF + G Sbjct: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGG 180 Query: 559 KAKGVERMKAITVANQIKDQDHNGRADIEVVDSEAHDGNLRQVL 690 K+ +ER KA +A I+D + G+A +E+V + QVL Sbjct: 181 KSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVL 224 >BC014549-1|AAH14549.1| 348|Homo sapiens capping protein (actin filament), gelsolin-like protein. Length = 348 Score = 164 bits (399), Expect = 2e-40 Identities = 84/224 (37%), Positives = 131/224 (58%), Gaps = 1/224 (0%) Frame = +1 Query: 22 MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 201 +P+ F + + PGL +WR+E +PV V + G+F+SGDSY+VL+ ++ + Sbjct: 5 IPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEE---VSHL 61 Query: 202 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 381 H W+G ++S+DE GA A+L V+L+ + VQHREVQ ES F+ YF ++Y +GG Sbjct: 62 HLWIGQQSSRDEQGACAVLAVHLNTLLGE-RPVQHREVQGNESDLFMSYFPRGLKYQEGG 120 Query: 382 HASGFSHVTINEGTE-KRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGE 558 S F + K+L+Q+KGK+N+R + ++S N GDCFILD+ IF + G Sbjct: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGG 180 Query: 559 KAKGVERMKAITVANQIKDQDHNGRADIEVVDSEAHDGNLRQVL 690 K+ +ER KA +A I+D + G+A +E+V + QVL Sbjct: 181 KSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVL 224 >BC000728-1|AAH00728.1| 348|Homo sapiens capping protein (actin filament), gelsolin-like protein. Length = 348 Score = 164 bits (399), Expect = 2e-40 Identities = 84/224 (37%), Positives = 131/224 (58%), Gaps = 1/224 (0%) Frame = +1 Query: 22 MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 201 +P+ F + + PGL +WR+E +PV V + G+F+SGDSY+VL+ ++ + Sbjct: 5 IPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEE---VSHL 61 Query: 202 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 381 H W+G ++S+DE GA A+L V+L+ + VQHREVQ ES F+ YF ++Y +GG Sbjct: 62 HLWIGQQSSRDEQGACAVLAVHLNTLLGE-RPVQHREVQGNESDLFMSYFPRGLKYQEGG 120 Query: 382 HASGFSHVTINEGTE-KRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGE 558 S F + K+L+Q+KGK+N+R + ++S N GDCFILD+ IF + G Sbjct: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGG 180 Query: 559 KAKGVERMKAITVANQIKDQDHNGRADIEVVDSEAHDGNLRQVL 690 K+ +ER KA +A I+D + G+A +E+V + QVL Sbjct: 181 KSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVL 224 >AC062037-3|AAY24128.1| 348|Homo sapiens unknown protein. Length = 348 Score = 164 bits (399), Expect = 2e-40 Identities = 84/224 (37%), Positives = 131/224 (58%), Gaps = 1/224 (0%) Frame = +1 Query: 22 MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 201 +P+ F + + PGL +WR+E +PV V + G+F+SGDSY+VL+ ++ + Sbjct: 5 IPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEE---VSHL 61 Query: 202 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 381 H W+G ++S+DE GA A+L V+L+ + VQHREVQ ES F+ YF ++Y +GG Sbjct: 62 HLWIGQQSSRDEQGACAVLAVHLNTLLGE-RPVQHREVQGNESDLFMSYFPRGLKYQEGG 120 Query: 382 HASGFSHVTINEGTE-KRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGE 558 S F + K+L+Q+KGK+N+R + ++S N GDCFILD+ IF + G Sbjct: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGG 180 Query: 559 KAKGVERMKAITVANQIKDQDHNGRADIEVVDSEAHDGNLRQVL 690 K+ +ER KA +A I+D + G+A +E+V + QVL Sbjct: 181 KSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVL 224 >U12026-1|AAA92670.1| 172|Homo sapiens Cap-G protein. Length = 172 Score = 133 bits (321), Expect = 7e-31 Identities = 66/170 (38%), Positives = 102/170 (60%), Gaps = 1/170 (0%) Frame = +1 Query: 22 MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 201 +P+ F + + PGL +WR+E +PV V + G+F+SGDSY+VL+ ++ + Sbjct: 5 IPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEE---VSHL 61 Query: 202 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 381 H W+G ++S+DE GA A+L V+L + VQHREVQ ES F+ YF ++Y +GG Sbjct: 62 HLWIGQQSSRDEQGACAVLAVHL-NTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG 120 Query: 382 HASGFSHVTIN-EGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDV 528 S F + K+L+Q+KGK+N+R + ++S N GDCFILD+ Sbjct: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDL 170 >U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein. Length = 1269 Score = 125 bits (301), Expect = 2e-28 Identities = 73/203 (35%), Positives = 112/203 (55%), Gaps = 2/203 (0%) Frame = +1 Query: 49 DAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNT-TGDKDRLTWDIHFWLGSRT 225 D G+ PGL IW+IENF PV V + G FY D YIVL T D L W+I++W+G Sbjct: 494 DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 553 Query: 226 SQDEAGAAAILTVNLDDEQFQGSAVQH-REVQYYESKEFLEYFSPAIRYLKGGHASGFSH 402 + D+ +AI VNL + G+ + RE ES+EFL+ F I Y++GG ASGF + Sbjct: 554 TLDKKACSAIHAVNL--RNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGF-Y 610 Query: 403 VTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERM 582 + R++++ GK+N++++ V SL+ F+LD I+V+ G +A Sbjct: 611 TVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTT 670 Query: 583 KAITVANQIKDQDHNGRADIEVV 651 KA A +I + G+A+I ++ Sbjct: 671 KARLFAEKINKNERKGKAEITLL 693 >U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog protein. Length = 1268 Score = 125 bits (301), Expect = 2e-28 Identities = 73/203 (35%), Positives = 112/203 (55%), Gaps = 2/203 (0%) Frame = +1 Query: 49 DAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNT-TGDKDRLTWDIHFWLGSRT 225 D G+ PGL IW+IENF PV V + G FY D YIVL T D L W+I++W+G Sbjct: 493 DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 552 Query: 226 SQDEAGAAAILTVNLDDEQFQGSAVQH-REVQYYESKEFLEYFSPAIRYLKGGHASGFSH 402 + D+ +AI VNL + G+ + RE ES+EFL+ F I Y++GG ASGF + Sbjct: 553 TLDKKACSAIHAVNL--RNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGF-Y 609 Query: 403 VTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERM 582 + R++++ GK+N++++ V SL+ F+LD I+V+ G +A Sbjct: 610 TVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTT 669 Query: 583 KAITVANQIKDQDHNGRADIEVV 651 KA A +I + G+A+I ++ Sbjct: 670 KARLFAEKINKNERKGKAEITLL 692 >BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog (Drosophila) protein. Length = 1269 Score = 125 bits (301), Expect = 2e-28 Identities = 73/203 (35%), Positives = 112/203 (55%), Gaps = 2/203 (0%) Frame = +1 Query: 49 DAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNT-TGDKDRLTWDIHFWLGSRT 225 D G+ PGL IW+IENF PV V + G FY D YIVL T D L W+I++W+G Sbjct: 494 DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 553 Query: 226 SQDEAGAAAILTVNLDDEQFQGSAVQH-REVQYYESKEFLEYFSPAIRYLKGGHASGFSH 402 + D+ +AI VNL + G+ + RE ES+EFL+ F I Y++GG ASGF + Sbjct: 554 TLDKKACSAIHAVNL--RNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGF-Y 610 Query: 403 VTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERM 582 + R++++ GK+N++++ V SL+ F+LD I+V+ G +A Sbjct: 611 TVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTT 670 Query: 583 KAITVANQIKDQDHNGRADIEVV 651 KA A +I + G+A+I ++ Sbjct: 671 KARLFAEKINKNERKGKAEITLL 693 >AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog variant protein. Length = 1101 Score = 125 bits (301), Expect = 2e-28 Identities = 73/203 (35%), Positives = 112/203 (55%), Gaps = 2/203 (0%) Frame = +1 Query: 49 DAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNT-TGDKDRLTWDIHFWLGSRT 225 D G+ PGL IW+IENF PV V + G FY D YIVL T D L W+I++W+G Sbjct: 481 DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 540 Query: 226 SQDEAGAAAILTVNLDDEQFQGSAVQH-REVQYYESKEFLEYFSPAIRYLKGGHASGFSH 402 + D+ +AI VNL + G+ + RE ES+EFL+ F I Y++GG ASGF + Sbjct: 541 TLDKKACSAIHAVNL--RNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGF-Y 597 Query: 403 VTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERM 582 + R++++ GK+N++++ V SL+ F+LD I+V+ G +A Sbjct: 598 TVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTT 657 Query: 583 KAITVANQIKDQDHNGRADIEVV 651 KA A +I + G+A+I ++ Sbjct: 658 KARLFAEKINKNERKGKAEITLL 680 >AL513122-7|CAI14416.1| 485|Homo sapiens gelsolin (amyloidosis, Finnish type) protein. Length = 485 Score = 91.9 bits (218), Expect = 2e-18 Identities = 66/186 (35%), Positives = 91/186 (48%), Gaps = 4/186 (2%) Frame = +1 Query: 73 EIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAAA 252 +IWRIE V V +G FY GDSYI+L R I+ W G++++QDE A+A Sbjct: 179 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASA 238 Query: 253 ILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYLKGGHASGFSHVTINEGTE 426 ILT L DE+ G+ VQ R VQ E + F P I Y KGG S T T Sbjct: 239 ILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIY-KGG-TSREGGQTAPAST- 294 Query: 427 KRLFQIKGKR--NVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVA 600 RLFQ++ R +V P +LN+ D F+L +++VG A E+ A + Sbjct: 295 -RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELL 353 Query: 601 NQIKDQ 618 ++ Q Sbjct: 354 RVLRAQ 359 >AK075198-1|BAC11465.1| 396|Homo sapiens protein ( Homo sapiens cDNA FLJ90717 fis, clone PLACE1008657, highly similar to Bovine mRNA for adseverin. ). Length = 396 Score = 81.0 bits (191), Expect = 4e-15 Identities = 68/206 (33%), Positives = 98/206 (47%), Gaps = 7/206 (3%) Frame = +1 Query: 16 PKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTW 195 P+M H D K +EIWR+EN + V + +G FY GD YI+L T + ++ Sbjct: 63 PQMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI-- 117 Query: 196 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRY 369 I+ W G+ ++DE +A LTV L D G AVQ R Q E L F P I Y Sbjct: 118 -IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIY 175 Query: 370 LKGGHASGFSHVTINEGTEKRLFQIKGKRNV----RVKQVKPTFESLNNGDCFILDV-DH 534 G G RLFQ+ +RN+ R+ +V SLN+ D F+L + + Sbjct: 176 KNGTSKKGGQ----APAPPTRLFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLPQN 229 Query: 535 QIFVFVGEKAKGVERMKAITVANQIK 612 +++VG+ A E A VA+ +K Sbjct: 230 SGYIWVGKGASQEEEKGAEYVASVLK 255 Score = 35.1 bits (77), Expect = 0.25 Identities = 16/50 (32%), Positives = 28/50 (56%) Frame = +1 Query: 484 TFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 633 T + L D +LD QIF+++G+ A VE+ +++ A + D +GR Sbjct: 317 TQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGR 366 >AK027778-1|BAB55361.1| 468|Homo sapiens protein ( Homo sapiens cDNA FLJ14872 fis, clone PLACE1002655, highly similar to ADSEVERIN. ). Length = 468 Score = 81.0 bits (191), Expect = 4e-15 Identities = 68/206 (33%), Positives = 98/206 (47%), Gaps = 7/206 (3%) Frame = +1 Query: 16 PKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTW 195 P+M H D K +EIWR+EN + V + +G FY GD YI+L T + ++ Sbjct: 135 PQMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI-- 189 Query: 196 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRY 369 I+ W G+ ++DE +A LTV L D G AVQ R Q E L F P I Y Sbjct: 190 -IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIY 247 Query: 370 LKGGHASGFSHVTINEGTEKRLFQIKGKRNV----RVKQVKPTFESLNNGDCFILDV-DH 534 G G RLFQ+ +RN+ R+ +V SLN+ D F+L + + Sbjct: 248 KNGTSKKGGQ----APAPPTRLFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLPQN 301 Query: 535 QIFVFVGEKAKGVERMKAITVANQIK 612 +++VG+ A E A VA+ +K Sbjct: 302 SGYIWVGKGASQEEEKGAEYVASVLK 327 Score = 35.1 bits (77), Expect = 0.25 Identities = 16/50 (32%), Positives = 28/50 (56%) Frame = +1 Query: 484 TFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 633 T + L D +LD QIF+++G+ A VE+ +++ A + D +GR Sbjct: 389 TQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGR 438 >BC075797-1|AAH75797.1| 85|Homo sapiens Unknown (protein for MGC:87550) protein. Length = 85 Score = 72.5 bits (170), Expect = 1e-12 Identities = 30/61 (49%), Positives = 42/61 (68%) Frame = +1 Query: 34 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 213 H+ FA AG++ GL++WRIE E V VP++ G FY GD+Y+VL+T T+ +HFWL Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWL 66 Query: 214 G 216 G Sbjct: 67 G 67 >X07066-1|CAA30102.1| 69|Homo sapiens protein ( Human gene for gelsolin exon 4. ). Length = 69 Score = 71.3 bits (167), Expect = 3e-12 Identities = 28/62 (45%), Positives = 44/62 (70%), Gaps = 1/62 (1%) Frame = +1 Query: 34 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 210 H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++ L +D+H+W Sbjct: 8 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 67 Query: 211 LG 216 LG Sbjct: 68 LG 69 >D88154-1|BAA21668.1| 686|Homo sapiens villin-like protein protein. Length = 686 Score = 62.1 bits (144), Expect = 2e-09 Identities = 55/205 (26%), Positives = 85/205 (41%), Gaps = 5/205 (2%) Frame = +1 Query: 10 TRPKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRL 189 T+PK+ + D K +E+W I++ V + G +G+ Y+VL T R+ Sbjct: 205 TQPKLAAQLRMVDDGSGK--VEVWCIQDLHRQPVDPKRHGQLCAGNCYLVLYTYQRLGRV 262 Query: 190 TWDIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRY 369 + ++ W G + + DE A L D + G VQ E FL F + Sbjct: 263 QYILYLWQGHQATADEIEALNSNAEEL-DVMYGGVLVQEHVTMGSEPPHFLAIFQGQLVI 321 Query: 370 LK---GGHASGFSHVTINEGTEKRLFQIKG--KRNVRVKQVKPTFESLNNGDCFILDVDH 534 + G H G S T RLFQ++G N R +V SLN+ D F+L Sbjct: 322 FQERAGHHGKGQSAST------TRLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTAS 375 Query: 535 QIFVFVGEKAKGVERMKAITVANQI 609 +++ G+ G +R A V I Sbjct: 376 VCYLWFGKGCNGDQREMARVVVTVI 400 Score = 29.9 bits (64), Expect = 9.3 Identities = 15/47 (31%), Positives = 26/47 (55%), Gaps = 1/47 (2%) Frame = +1 Query: 553 GEKAKGVERMKAITVANQIKDQDHNG-RADIEVVDSEAHDGNLRQVL 690 G K E+ + + + ++D++ G RA I VVD EA +L Q++ Sbjct: 7 GPKTSISEKARGLALTYSLRDRERGGGRAQIGVVDDEAKAPDLMQIM 53 >BC004300-1|AAH04300.1| 672|Homo sapiens VILL protein protein. Length = 672 Score = 62.1 bits (144), Expect = 2e-09 Identities = 55/205 (26%), Positives = 85/205 (41%), Gaps = 5/205 (2%) Frame = +1 Query: 10 TRPKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRL 189 T+PK+ + D K +E+W I++ V + G +G+ Y+VL T R+ Sbjct: 191 TQPKLAAQLRMVDDGSGK--VEVWCIQDLHRQPVDPKRHGQLCAGNCYLVLYTYQRLGRV 248 Query: 190 TWDIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRY 369 + ++ W G + + DE A L D + G VQ E FL F + Sbjct: 249 QYILYLWQGHQATADEIEALNSNAEEL-DVMYGGVLVQEHVTMGSEPPHFLAIFQGQLVI 307 Query: 370 LK---GGHASGFSHVTINEGTEKRLFQIKG--KRNVRVKQVKPTFESLNNGDCFILDVDH 534 + G H G S T RLFQ++G N R +V SLN+ D F+L Sbjct: 308 FQERAGHHGKGQSAST------TRLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTAS 361 Query: 535 QIFVFVGEKAKGVERMKAITVANQI 609 +++ G+ G +R A V I Sbjct: 362 VCYLWFGKGCNGDQREMARVVVTVI 386 Score = 29.9 bits (64), Expect = 9.3 Identities = 15/47 (31%), Positives = 26/47 (55%), Gaps = 1/47 (2%) Frame = +1 Query: 553 GEKAKGVERMKAITVANQIKDQDHNG-RADIEVVDSEAHDGNLRQVL 690 G K E+ + + + ++D++ G RA I VVD EA +L Q++ Sbjct: 7 GPKTSISEKARGLALTYSLRDRERGGGRAQIGVVDDEAKAPDLMQIM 53 >BC000243-1|AAH00243.1| 686|Homo sapiens VILL protein protein. Length = 686 Score = 62.1 bits (144), Expect = 2e-09 Identities = 55/205 (26%), Positives = 85/205 (41%), Gaps = 5/205 (2%) Frame = +1 Query: 10 TRPKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRL 189 T+PK+ + D K +E+W I++ V + G +G+ Y+VL T R+ Sbjct: 205 TQPKLAAQLRMVDDGSGK--VEVWCIQDLHRQPVDPKRHGQLCAGNCYLVLYTYQRLGRV 262 Query: 190 TWDIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRY 369 + ++ W G + + DE A L D + G VQ E FL F + Sbjct: 263 QYILYLWQGHQATADEIEALNSNAEEL-DVMYGGVLVQEHVTMGSEPPHFLAIFQGQLVI 321 Query: 370 LK---GGHASGFSHVTINEGTEKRLFQIKG--KRNVRVKQVKPTFESLNNGDCFILDVDH 534 + G H G S T RLFQ++G N R +V SLN+ D F+L Sbjct: 322 FQERAGHHGKGQSAST------TRLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTAS 375 Query: 535 QIFVFVGEKAKGVERMKAITVANQI 609 +++ G+ G +R A V I Sbjct: 376 VCYLWFGKGCNGDQREMARVVVTVI 400 Score = 29.9 bits (64), Expect = 9.3 Identities = 15/47 (31%), Positives = 26/47 (55%), Gaps = 1/47 (2%) Frame = +1 Query: 553 GEKAKGVERMKAITVANQIKDQDHNG-RADIEVVDSEAHDGNLRQVL 690 G K E+ + + + ++D++ G RA I VVD EA +L Q++ Sbjct: 7 GPKTSISEKARGLALTYSLRDRERGGGRAQIGVVDDEAKAPDLMQIM 53 >AL160060-2|CAH71300.1| 2214|Homo sapiens supervillin protein. Length = 2214 Score = 57.6 bits (133), Expect(2) = 2e-08 Identities = 28/66 (42%), Positives = 43/66 (65%) Frame = +1 Query: 433 LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIK 612 L QIKG+R+V+ + V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+ Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504 Query: 613 DQDHNG 630 + G Sbjct: 1505 TKRELG 1510 Score = 50.0 bits (114), Expect = 8e-06 Identities = 53/203 (26%), Positives = 94/203 (46%), Gaps = 20/203 (9%) Frame = +1 Query: 70 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 204 +++W I F+ +PK G F+ GD+Y+V G + + + Sbjct: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813 Query: 205 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 381 FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F + Sbjct: 1814 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1865 Query: 382 HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 549 H+ N +E RL+ ++G+ V + +V SL + +L+V+ I+++ Sbjct: 1866 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1925 Query: 550 VGEKAKGVERMKAITVANQIKDQ 618 G KA+ + T AN+IK+Q Sbjct: 1926 HGCKAQAHTKEVGRTAANKIKEQ 1948 Score = 20.6 bits (41), Expect(2) = 2e-08 Identities = 9/41 (21%), Positives = 20/41 (48%) Frame = +1 Query: 211 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 333 L S++ ++ +VNL ++ SAV ++ + + K Sbjct: 1409 LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1449 >AL158167-3|CAI15237.1| 2214|Homo sapiens supervillin protein. Length = 2214 Score = 57.6 bits (133), Expect(2) = 2e-08 Identities = 28/66 (42%), Positives = 43/66 (65%) Frame = +1 Query: 433 LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIK 612 L QIKG+R+V+ + V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+ Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504 Query: 613 DQDHNG 630 + G Sbjct: 1505 TKRELG 1510 Score = 50.0 bits (114), Expect = 8e-06 Identities = 53/203 (26%), Positives = 94/203 (46%), Gaps = 20/203 (9%) Frame = +1 Query: 70 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 204 +++W I F+ +PK G F+ GD+Y+V G + + + Sbjct: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813 Query: 205 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 381 FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F + Sbjct: 1814 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1865 Query: 382 HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 549 H+ N +E RL+ ++G+ V + +V SL + +L+V+ I+++ Sbjct: 1866 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1925 Query: 550 VGEKAKGVERMKAITVANQIKDQ 618 G KA+ + T AN+IK+Q Sbjct: 1926 HGCKAQAHTKEVGRTAANKIKEQ 1948 Score = 20.6 bits (41), Expect(2) = 2e-08 Identities = 9/41 (21%), Positives = 20/41 (48%) Frame = +1 Query: 211 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 333 L S++ ++ +VNL ++ SAV ++ + + K Sbjct: 1409 LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1449 >AF109135-1|AAD14682.1| 2214|Homo sapiens archvillin protein. Length = 2214 Score = 57.6 bits (133), Expect(2) = 2e-08 Identities = 28/66 (42%), Positives = 43/66 (65%) Frame = +1 Query: 433 LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIK 612 L QIKG+R+V+ + V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+ Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504 Query: 613 DQDHNG 630 + G Sbjct: 1505 TKRELG 1510 Score = 50.0 bits (114), Expect = 8e-06 Identities = 53/203 (26%), Positives = 94/203 (46%), Gaps = 20/203 (9%) Frame = +1 Query: 70 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 204 +++W I F+ +PK G F+ GD+Y+V G + + + Sbjct: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813 Query: 205 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 381 FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F + Sbjct: 1814 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1865 Query: 382 HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 549 H+ N +E RL+ ++G+ V + +V SL + +L+V+ I+++ Sbjct: 1866 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1925 Query: 550 VGEKAKGVERMKAITVANQIKDQ 618 G KA+ + T AN+IK+Q Sbjct: 1926 HGCKAQAHTKEVGRTAANKIKEQ 1948 Score = 20.6 bits (41), Expect(2) = 2e-08 Identities = 9/41 (21%), Positives = 20/41 (48%) Frame = +1 Query: 211 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 333 L S++ ++ +VNL ++ SAV ++ + + K Sbjct: 1409 LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1449 >AL160060-1|CAH71301.1| 1788|Homo sapiens supervillin protein. Length = 1788 Score = 57.6 bits (133), Expect(2) = 2e-08 Identities = 28/66 (42%), Positives = 43/66 (65%) Frame = +1 Query: 433 LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIK 612 L QIKG+R+V+ + V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+ Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078 Query: 613 DQDHNG 630 + G Sbjct: 1079 TKRELG 1084 Score = 50.0 bits (114), Expect = 8e-06 Identities = 53/203 (26%), Positives = 94/203 (46%), Gaps = 20/203 (9%) Frame = +1 Query: 70 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 204 +++W I F+ +PK G F+ GD+Y+V G + + + Sbjct: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387 Query: 205 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 381 FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F + Sbjct: 1388 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1439 Query: 382 HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 549 H+ N +E RL+ ++G+ V + +V SL + +L+V+ I+++ Sbjct: 1440 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1499 Query: 550 VGEKAKGVERMKAITVANQIKDQ 618 G KA+ + T AN+IK+Q Sbjct: 1500 HGCKAQAHTKEVGRTAANKIKEQ 1522 Score = 20.6 bits (41), Expect(2) = 2e-08 Identities = 9/41 (21%), Positives = 20/41 (48%) Frame = +1 Query: 211 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 333 L S++ ++ +VNL ++ SAV ++ + + K Sbjct: 983 LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1023 >AL158167-2|CAI15236.1| 1788|Homo sapiens supervillin protein. Length = 1788 Score = 57.6 bits (133), Expect(2) = 2e-08 Identities = 28/66 (42%), Positives = 43/66 (65%) Frame = +1 Query: 433 LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIK 612 L QIKG+R+V+ + V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+ Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078 Query: 613 DQDHNG 630 + G Sbjct: 1079 TKRELG 1084 Score = 50.0 bits (114), Expect = 8e-06 Identities = 53/203 (26%), Positives = 94/203 (46%), Gaps = 20/203 (9%) Frame = +1 Query: 70 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 204 +++W I F+ +PK G F+ GD+Y+V G + + + Sbjct: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387 Query: 205 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 381 FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F + Sbjct: 1388 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1439 Query: 382 HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 549 H+ N +E RL+ ++G+ V + +V SL + +L+V+ I+++ Sbjct: 1440 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1499 Query: 550 VGEKAKGVERMKAITVANQIKDQ 618 G KA+ + T AN+IK+Q Sbjct: 1500 HGCKAQAHTKEVGRTAANKIKEQ 1522 Score = 20.6 bits (41), Expect(2) = 2e-08 Identities = 9/41 (21%), Positives = 20/41 (48%) Frame = +1 Query: 211 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 333 L S++ ++ +VNL ++ SAV ++ + + K Sbjct: 983 LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1023 >AF051851-1|AAC64696.1| 1788|Homo sapiens supervillin protein. Length = 1788 Score = 57.6 bits (133), Expect(2) = 2e-08 Identities = 28/66 (42%), Positives = 43/66 (65%) Frame = +1 Query: 433 LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIK 612 L QIKG+R+V+ + V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+ Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078 Query: 613 DQDHNG 630 + G Sbjct: 1079 TKRELG 1084 Score = 50.0 bits (114), Expect = 8e-06 Identities = 53/203 (26%), Positives = 94/203 (46%), Gaps = 20/203 (9%) Frame = +1 Query: 70 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 204 +++W I F+ +PK G F+ GD+Y+V G + + + Sbjct: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387 Query: 205 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 381 FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F + Sbjct: 1388 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1439 Query: 382 HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 549 H+ N +E RL+ ++G+ V + +V SL + +L+V+ I+++ Sbjct: 1440 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1499 Query: 550 VGEKAKGVERMKAITVANQIKDQ 618 G KA+ + T AN+IK+Q Sbjct: 1500 HGCKAQAHTKEVGRTAANKIKEQ 1522 Score = 20.6 bits (41), Expect(2) = 2e-08 Identities = 9/41 (21%), Positives = 20/41 (48%) Frame = +1 Query: 211 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 333 L S++ ++ +VNL ++ SAV ++ + + K Sbjct: 983 LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1023 >AF051850-1|AAC64695.1| 1788|Homo sapiens supervillin protein. Length = 1788 Score = 57.6 bits (133), Expect(2) = 2e-08 Identities = 28/66 (42%), Positives = 43/66 (65%) Frame = +1 Query: 433 LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIK 612 L QIKG+R+V+ + V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+ Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078 Query: 613 DQDHNG 630 + G Sbjct: 1079 TKRELG 1084 Score = 50.0 bits (114), Expect = 8e-06 Identities = 53/203 (26%), Positives = 94/203 (46%), Gaps = 20/203 (9%) Frame = +1 Query: 70 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 204 +++W I F+ +PK G F+ GD+Y+V G + + + Sbjct: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387 Query: 205 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 381 FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F + Sbjct: 1388 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1439 Query: 382 HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 549 H+ N +E RL+ ++G+ V + +V SL + +L+V+ I+++ Sbjct: 1440 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1499 Query: 550 VGEKAKGVERMKAITVANQIKDQ 618 G KA+ + T AN+IK+Q Sbjct: 1500 HGCKAQAHTKEVGRTAANKIKEQ 1522 Score = 20.6 bits (41), Expect(2) = 2e-08 Identities = 9/41 (21%), Positives = 20/41 (48%) Frame = +1 Query: 211 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 333 L S++ ++ +VNL ++ SAV ++ + + K Sbjct: 983 LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1023 >BC017491-1|AAH17491.1| 285|Homo sapiens Similar to gelsolin (amyloidosis, Finnish type) protein. Length = 285 Score = 54.8 bits (126), Expect = 3e-07 Identities = 46/136 (33%), Positives = 65/136 (47%), Gaps = 4/136 (2%) Frame = +1 Query: 223 TSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYLKGGHASGF 396 ++QDE A+AILT L DE+ G+ VQ R VQ E + F P I Y KGG S Sbjct: 1 STQDEVAASAILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIY-KGG-TSRE 57 Query: 397 SHVTINEGTEKRLFQIKGKR--NVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKG 570 T T RLFQ++ R +V P +LN+ D F+L +++VG A Sbjct: 58 GGQTAPAST--RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASE 115 Query: 571 VERMKAITVANQIKDQ 618 E+ A + ++ Q Sbjct: 116 AEKTGAQELLRVLRAQ 131 Score = 32.3 bits (70), Expect = 1.7 Identities = 16/48 (33%), Positives = 27/48 (56%) Frame = +1 Query: 490 ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 633 E L D +LD Q+FV+VG+ ++ E+ +A+T A + + D R Sbjct: 194 EDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANR 241 >AK092426-1|BAC03887.1| 258|Homo sapiens protein ( Homo sapiens cDNA FLJ35107 fis, clone PLACE6006871, moderately similar to SUPPRESSOR PROTEIN SRP40. ). Length = 258 Score = 35.5 bits (78), Expect = 0.19 Identities = 38/142 (26%), Positives = 65/142 (45%), Gaps = 3/142 (2%) Frame = +2 Query: 56 AGSRVSKYGGLRTSNRSPFRRLSSV---SSTPGTPTLY*TPQAIRTV*HGTSISGSARGP 226 AG GG R+S+ S LSS SS P + + +P + + S S S+ P Sbjct: 25 AGPNALGSGGSRSSSSSSRSILSSSILSSSIPSSSSSSSSPSSSHSS-SSPSSSHSSSSP 83 Query: 227 ARTKPARRPSSR*TWTTNNSRDQRYSTERSNITSPRSS*NISHQPSAI*KADTPQASAT* 406 + + PSS + ++++S S+ S+ +SP SS + S S + +P +S++ Sbjct: 84 SSSSSTSSPSSSSSSSSSSSPSSSNSSSSSSSSSPSSS-SSSSSSSPSSSSSSPSSSSSS 142 Query: 407 RSMREQRNDSSRSRVKETSALS 472 S + SS S +S+ S Sbjct: 143 SSSSPSSSSSSPSSSSSSSSSS 164 >BC117319-1|AAI17320.1| 257|Homo sapiens TPRXL protein protein. Length = 257 Score = 33.1 bits (72), Expect = 0.99 Identities = 36/142 (25%), Positives = 64/142 (45%), Gaps = 3/142 (2%) Frame = +2 Query: 56 AGSRVSKYGGLRTSNRSPFRRLSSV---SSTPGTPTLY*TPQAIRTV*HGTSISGSARGP 226 AG GG R+S+ S LSS SS P + + +P + + S S S+ P Sbjct: 25 AGPNALGSGGSRSSSSSSRSILSSSILSSSIPSSSSSSSSPSSSHSS-SSPSSSHSSSSP 83 Query: 227 ARTKPARRPSSR*TWTTNNSRDQRYSTERSNITSPRSS*NISHQPSAI*KADTPQASAT* 406 + + PSS + ++++ S+ S+ + SS + S PS+ + +P +S++ Sbjct: 84 SSSSSTSSPSSSSSSSSSSPSSSNSSSSSSSSSPSSSSSSSSSSPSS--SSSSPSSSSSS 141 Query: 407 RSMREQRNDSSRSRVKETSALS 472 S + SS S +S+ S Sbjct: 142 SSSSPSSSSSSPSSSSSSSSSS 163 >AL513122-9|CAI14417.1| 207|Homo sapiens gelsolin (amyloidosis, Finnish type) protein. Length = 207 Score = 32.3 bits (70), Expect = 1.7 Identities = 16/48 (33%), Positives = 27/48 (56%) Frame = +1 Query: 490 ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 633 E L D +LD Q+FV+VG+ ++ E+ +A+T A + + D R Sbjct: 116 EDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANR 163 >BC106877-1|AAI06878.1| 663|Homo sapiens chromosome 1 open reading frame 106 protein. Length = 663 Score = 31.9 bits (69), Expect = 2.3 Identities = 22/69 (31%), Positives = 33/69 (47%) Frame = -1 Query: 392 PEACPPFK*RMAGEKYSRNSLDS*YWTSRCCTADPWNCSSSKFTVRMAAAPASSWLVLEP 213 PEA P + + + SLD Y R +++PW+ SSS T ASS +LEP Sbjct: 309 PEAGSPERAPVQNSPWKETSLDHPYEKPRK-SSEPWSESSSPATTPQDGPSASSLWLLEP 367 Query: 212 SQKWMSHVR 186 + + +R Sbjct: 368 ASYHVVPIR 376 >AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ protein protein. Length = 3222 Score = 31.9 bits (69), Expect = 2.3 Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 5/63 (7%) Frame = +1 Query: 481 PTFESLNNGDCFILDVDHQ--IFV---FVGEKAKGVERMKAITVANQIKDQDHNGRADIE 645 P F S D +LDV+ IF F+ E + + K +TV+ KD NG+ D E Sbjct: 945 PPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPRKILTVSAMDKDSGPNGQLDYE 1004 Query: 646 VVD 654 +V+ Sbjct: 1005 IVN 1007 >AK001763-1|BAA91892.1| 663|Homo sapiens protein ( Homo sapiens cDNA FLJ10901 fis, clone NT2RP5003524. ). Length = 663 Score = 31.9 bits (69), Expect = 2.3 Identities = 22/69 (31%), Positives = 33/69 (47%) Frame = -1 Query: 392 PEACPPFK*RMAGEKYSRNSLDS*YWTSRCCTADPWNCSSSKFTVRMAAAPASSWLVLEP 213 PEA P + + + SLD Y R +++PW+ SSS T ASS +LEP Sbjct: 309 PEAGSPERAPVQNSPWKETSLDHPYEKPRK-SSEPWSESSSPATTPQDGPSASSLWLLEP 367 Query: 212 SQKWMSHVR 186 + + +R Sbjct: 368 ASYHVVPIR 376 >D31661-1|BAA06506.1| 981|Homo sapiens tyrosine kinase precursor protein. Length = 981 Score = 30.3 bits (65), Expect = 7.0 Identities = 29/123 (23%), Positives = 56/123 (45%), Gaps = 4/123 (3%) Frame = +1 Query: 310 EVQYYESKEFLEYFSPAIRYLKGGHASGFSHVTIN--EGTEKRLFQIKGKRNVRVKQV-- 477 E+QYYE +E EY + AI+ S + VT+ + +FQ++ + + Sbjct: 464 ELQYYEKQELSEYNATAIK-------SPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSG 516 Query: 478 KPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRADIEVVDS 657 K F+++ D + + ++ + +G A G+ + A+ V + ++ RAD E D Sbjct: 517 KMYFQTMTEAD-YQTSIQEKLPLIIGSSAAGLVFLIAVVVIAIVCNRRGFERADSEYTDK 575 Query: 658 EAH 666 H Sbjct: 576 LQH 578 Database: human Posted date: Oct 23, 2007 1:18 PM Number of letters in database: 76,859,062 Number of sequences in database: 237,096 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 108,507,976 Number of Sequences: 237096 Number of extensions: 2360633 Number of successful extensions: 9559 Number of sequences better than 10.0: 48 Number of HSP's better than 10.0 without gapping: 9123 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 9486 length of database: 76,859,062 effective HSP length: 88 effective length of database: 55,994,614 effective search space used: 8175213644 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
- SilkBase 1999-2023 -