Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= epV31326
(628 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein. 118 2e-26
M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein. 118 2e-26
M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein. 118 2e-26
CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein. 118 2e-26
BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal ... 118 2e-26
BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal ... 118 2e-26
BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein. 118 2e-26
BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic pepti... 109 6e-24
AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4 pro... 109 6e-24
AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor prot... 109 6e-24
AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein. 109 6e-24
BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein. 95 2e-19
AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3 pro... 95 2e-19
M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein. 94 3e-19
J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein. 94 3e-19
BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein. 94 3e-19
BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein. 94 3e-19
BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein. 94 3e-19
AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein. 94 3e-19
AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternativ... 94 3e-19
X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mR... 93 6e-19
M26901-1|AAA60364.1| 403|Homo sapiens renin protein. 93 6e-19
M10152-1|AAD03461.1| 406|Homo sapiens renin protein. 93 6e-19
L00073-1|AAA60363.1| 406|Homo sapiens renin protein. 93 6e-19
CR536498-1|CAG38737.1| 406|Homo sapiens REN protein. 93 6e-19
BC047752-1|AAH47752.1| 406|Homo sapiens renin protein. 93 6e-19
BC033474-1|AAH33474.1| 406|Homo sapiens renin protein. 93 6e-19
AY436324-1|AAR03502.1| 403|Homo sapiens renin protein. 93 6e-19
AL592146-1|CAI16594.1| 406|Homo sapiens renin protein. 93 6e-19
AL592114-1|CAH71224.1| 406|Homo sapiens renin protein. 93 6e-19
U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein. 89 9e-18
M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein. 89 9e-18
M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein. 89 9e-18
J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein. 89 9e-18
BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinog... 89 9e-18
AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinog... 89 9e-18
M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein. 78 2e-14
J00287-1|AAA98529.1| 388|Homo sapiens PEP protein. 78 2e-14
BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I (... 78 2e-14
BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein. 60 6e-09
AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens ... 40 0.010
AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinog... 39 0.017
BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving ... 38 0.029
AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein. 38 0.029
AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving ... 38 0.029
AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein. 38 0.029
AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic ... 38 0.029
AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1 pro... 38 0.029
AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein. 38 0.029
AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein. 38 0.029
AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein. 38 0.029
AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein. 38 0.029
AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease ... 38 0.029
AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein. 38 0.029
AL365205-2|CAI95135.1| 140|Homo sapiens progastricsin (pepsinog... 37 0.067
DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving ... 36 0.089
BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving ... 36 0.089
BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving ... 36 0.089
AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving ... 36 0.089
AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving ... 36 0.089
AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic ... 36 0.089
AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase prot... 36 0.089
AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2 pro... 36 0.089
AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein. 36 0.089
AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving ... 36 0.089
AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving ... 36 0.089
AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving ... 36 0.089
AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving ... 36 0.089
AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving ... 36 0.089
AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein. 36 0.089
AF141344-1|AAG49447.1| 119|Homo sapiens LYST-interacting protei... 32 1.4
AK055141-1|BAB70862.1| 260|Homo sapiens protein ( Homo sapiens ... 32 1.9
BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain cont... 31 4.4
BC133035-1|AAI33036.1| 129|Homo sapiens keratin associated prot... 30 5.8
BC130399-1|AAI30400.1| 129|Homo sapiens keratin associated prot... 30 5.8
AB126075-1|BAD20202.1| 129|Homo sapiens keratin associated prot... 30 5.8
X85133-1|CAA59445.1| 948|Homo sapiens RB protein binding protei... 30 7.7
AY072922-1|AAL68925.1| 1625|Homo sapiens p53-associated cellular... 30 7.7
AF352051-1|AAL05625.1| 1616|Homo sapiens proliferation potential... 30 7.7
AB112075-1|BAC77637.1| 1758|Homo sapiens retinoblastoma binding ... 30 7.7
AB112074-1|BAC77636.1| 1792|Homo sapiens retinoblastoma binding ... 30 7.7
BC146666-1|AAI46667.1| 689|Homo sapiens SLC34A2 protein protein. 24 9.4
BC142704-1|AAI42705.1| 689|Homo sapiens SLC34A2 protein protein. 24 9.4
AF146796-1|AAF31328.1| 689|Homo sapiens sodium dependent phosph... 24 9.4
AK075015-1|BAC11354.1| 397|Homo sapiens protein ( Homo sapiens ... 24 9.9
>X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 118 bits (283), Expect = 2e-26
Identities = 58/100 (58%), Positives = 69/100 (69%), Gaps = 11/100 (11%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV----- 525
WVPS C +IAC +H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V
Sbjct: 104 WVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSA 163
Query: 526 ------GGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
GG+KV RQ F EA +PG+ F+AAKFDGILGMA+
Sbjct: 164 SSASALGGVKVERQVFGEATKQPGITFIAAKFDGILGMAY 203
Score = 85.8 bits (203), Expect = 1e-16
Identities = 48/93 (51%), Positives = 56/93 (60%), Gaps = 11/93 (11%)
Frame = +3
Query: 114 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 260
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 261 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNL 359
L NY+DAQYYG I IGTPPQ F VVFDTGSSNL
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNL 103
>M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 118 bits (283), Expect = 2e-26
Identities = 58/100 (58%), Positives = 69/100 (69%), Gaps = 11/100 (11%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV----- 525
WVPS C +IAC +H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V
Sbjct: 104 WVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSA 163
Query: 526 ------GGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
GG+KV RQ F EA +PG+ F+AAKFDGILGMA+
Sbjct: 164 SSASALGGVKVERQVFGEATKQPGITFIAAKFDGILGMAY 203
Score = 85.8 bits (203), Expect = 1e-16
Identities = 48/93 (51%), Positives = 56/93 (60%), Gaps = 11/93 (11%)
Frame = +3
Query: 114 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 260
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 261 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNL 359
L NY+DAQYYG I IGTPPQ F VVFDTGSSNL
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNL 103
>M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 118 bits (283), Expect = 2e-26
Identities = 58/100 (58%), Positives = 69/100 (69%), Gaps = 11/100 (11%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV----- 525
WVPS C +IAC +H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V
Sbjct: 104 WVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSA 163
Query: 526 ------GGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
GG+KV RQ F EA +PG+ F+AAKFDGILGMA+
Sbjct: 164 SSASALGGVKVERQVFGEATKQPGITFIAAKFDGILGMAY 203
Score = 85.8 bits (203), Expect = 1e-16
Identities = 48/93 (51%), Positives = 56/93 (60%), Gaps = 11/93 (11%)
Frame = +3
Query: 114 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 260
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 261 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNL 359
L NY+DAQYYG I IGTPPQ F VVFDTGSSNL
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNL 103
>CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 118 bits (283), Expect = 2e-26
Identities = 58/100 (58%), Positives = 69/100 (69%), Gaps = 11/100 (11%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV----- 525
WVPS C +IAC +H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V
Sbjct: 104 WVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSA 163
Query: 526 ------GGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
GG+KV RQ F EA +PG+ F+AAKFDGILGMA+
Sbjct: 164 SSASALGGVKVERQVFGEATKQPGITFIAAKFDGILGMAY 203
Score = 85.8 bits (203), Expect = 1e-16
Identities = 48/93 (51%), Positives = 56/93 (60%), Gaps = 11/93 (11%)
Frame = +3
Query: 114 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 260
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 261 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNL 359
L NY+DAQYYG I IGTPPQ F VVFDTGSSNL
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNL 103
>BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 118 bits (283), Expect = 2e-26
Identities = 58/100 (58%), Positives = 69/100 (69%), Gaps = 11/100 (11%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV----- 525
WVPS C +IAC +H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V
Sbjct: 104 WVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSA 163
Query: 526 ------GGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
GG+KV RQ F EA +PG+ F+AAKFDGILGMA+
Sbjct: 164 SSASALGGVKVERQVFGEATKQPGITFIAAKFDGILGMAY 203
Score = 85.8 bits (203), Expect = 1e-16
Identities = 48/93 (51%), Positives = 56/93 (60%), Gaps = 11/93 (11%)
Frame = +3
Query: 114 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 260
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 261 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNL 359
L NY+DAQYYG I IGTPPQ F VVFDTGSSNL
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNL 103
>BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 118 bits (283), Expect = 2e-26
Identities = 58/100 (58%), Positives = 69/100 (69%), Gaps = 11/100 (11%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV----- 525
WVPS C +IAC +H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V
Sbjct: 104 WVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSA 163
Query: 526 ------GGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
GG+KV RQ F EA +PG+ F+AAKFDGILGMA+
Sbjct: 164 SSASALGGVKVERQVFGEATKQPGITFIAAKFDGILGMAY 203
Score = 85.8 bits (203), Expect = 1e-16
Identities = 48/93 (51%), Positives = 56/93 (60%), Gaps = 11/93 (11%)
Frame = +3
Query: 114 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 260
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 261 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNL 359
L NY+DAQYYG I IGTPPQ F VVFDTGSSNL
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNL 103
>BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 118 bits (283), Expect = 2e-26
Identities = 58/100 (58%), Positives = 69/100 (69%), Gaps = 11/100 (11%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV----- 525
WVPS C +IAC +H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V
Sbjct: 104 WVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSA 163
Query: 526 ------GGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
GG+KV RQ F EA +PG+ F+AAKFDGILGMA+
Sbjct: 164 SSASALGGVKVERQVFGEATKQPGITFIAAKFDGILGMAY 203
Score = 85.8 bits (203), Expect = 1e-16
Identities = 48/93 (51%), Positives = 56/93 (60%), Gaps = 11/93 (11%)
Frame = +3
Query: 114 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 260
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 261 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNL 359
L NY+DAQYYG I IGTPPQ F VVFDTGSSNL
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNL 103
>BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic
peptidase protein.
Length = 420
Score = 109 bits (263), Expect = 6e-24
Identities = 45/89 (50%), Positives = 64/89 (71%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS++CH+ ++ C LH+++D + S ++ ANGT+FAIQYG+G + G LS D +T+GG+K
Sbjct: 103 WVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKG 162
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
F EA+ EP L F A FDGILG+ F
Sbjct: 163 ASVIFGEALWEPSLVFAFAHFDGILGLGF 191
Score = 67.3 bits (157), Expect = 4e-11
Identities = 38/84 (45%), Positives = 48/84 (57%), Gaps = 5/84 (5%)
Frame = +3
Query: 123 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 287
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRTLNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 288 YGVISIGTPPQSFKVVFDTGSSNL 359
+G I +GTPPQ+F V FDTGSSNL
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNL 102
>AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4
protein.
Length = 420
Score = 109 bits (263), Expect = 6e-24
Identities = 45/89 (50%), Positives = 64/89 (71%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS++CH+ ++ C LH+++D + S ++ ANGT+FAIQYG+G + G LS D +T+GG+K
Sbjct: 103 WVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKG 162
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
F EA+ EP L F A FDGILG+ F
Sbjct: 163 ASVIFGEALWEPSLVFAFAHFDGILGLGF 191
Score = 66.9 bits (156), Expect = 5e-11
Identities = 38/84 (45%), Positives = 48/84 (57%), Gaps = 5/84 (5%)
Frame = +3
Query: 123 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 287
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 288 YGVISIGTPPQSFKVVFDTGSSNL 359
+G I +GTPPQ+F V FDTGSSNL
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNL 102
>AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor
protein.
Length = 420
Score = 109 bits (263), Expect = 6e-24
Identities = 45/89 (50%), Positives = 64/89 (71%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS++CH+ ++ C LH+++D + S ++ ANGT+FAIQYG+G + G LS D +T+GG+K
Sbjct: 103 WVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKG 162
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
F EA+ EP L F A FDGILG+ F
Sbjct: 163 ASVIFGEALWEPSLVFAFAHFDGILGLGF 191
Score = 66.9 bits (156), Expect = 5e-11
Identities = 38/84 (45%), Positives = 48/84 (57%), Gaps = 5/84 (5%)
Frame = +3
Query: 123 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 287
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 288 YGVISIGTPPQSFKVVFDTGSSNL 359
+G I +GTPPQ+F V FDTGSSNL
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNL 102
>AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein.
Length = 420
Score = 109 bits (263), Expect = 6e-24
Identities = 45/89 (50%), Positives = 64/89 (71%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS++CH+ ++ C LH+++D + S ++ ANGT+FAIQYG+G + G LS D +T+GG+K
Sbjct: 103 WVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKG 162
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
F EA+ EP L F A FDGILG+ F
Sbjct: 163 ASVIFGEALWEPSLVFAFAHFDGILGLGF 191
Score = 66.9 bits (156), Expect = 5e-11
Identities = 38/84 (45%), Positives = 48/84 (57%), Gaps = 5/84 (5%)
Frame = +3
Query: 123 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 287
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 288 YGVISIGTPPQSFKVVFDTGSSNL 359
+G I +GTPPQ+F V FDTGSSNL
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNL 102
>BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein.
Length = 464
Score = 95.1 bits (226), Expect = 2e-19
Identities = 38/89 (42%), Positives = 60/89 (67%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS++CH+ ++ C H++++ S ++ +GT+FAIQYG+G + G LS D +T+GG+K
Sbjct: 99 WVPSRRCHFFSVPCWFHHRFNPNASSSFKPSGTKFAIQYGTGRVDGILSEDKLTIGGIKG 158
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
F EA+ E L F ++ DGILG+ F
Sbjct: 159 ASVIFGEALWESSLVFTVSRPDGILGLGF 187
Score = 64.9 bits (151), Expect = 2e-10
Identities = 36/77 (46%), Positives = 46/77 (59%), Gaps = 5/77 (6%)
Frame = +3
Query: 144 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 308
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 22 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 81
Query: 309 TPPQSFKVVFDTGSSNL 359
TPPQ+F V FDTGSSNL
Sbjct: 82 TPPQNFTVAFDTGSSNL 98
>AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3
protein.
Length = 450
Score = 95.1 bits (226), Expect = 2e-19
Identities = 38/89 (42%), Positives = 60/89 (67%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS++CH+ ++ C H++++ S ++ +GT+FAIQYG+G + G LS D +T+GG+K
Sbjct: 103 WVPSRRCHFFSVPCWFHHRFNPNASSSFKPSGTKFAIQYGTGRVDGILSEDKLTIGGIKG 162
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
F EA+ E L F ++ DGILG+ F
Sbjct: 163 ASVIFGEALWESSLVFTVSRPDGILGLGF 191
Score = 64.9 bits (151), Expect = 2e-10
Identities = 36/77 (46%), Positives = 46/77 (59%), Gaps = 5/77 (6%)
Frame = +3
Query: 144 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 308
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 26 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 85
Query: 309 TPPQSFKVVFDTGSSNL 359
TPPQ+F V FDTGSSNL
Sbjct: 86 TPPQNFTVAFDTGSSNL 102
>M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 94.3 bits (224), Expect = 3e-19
Identities = 45/89 (50%), Positives = 59/89 (66%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS C T+ AC H+++ +S TY G F+IQYG+GSLSG + D V+V GL V
Sbjct: 103 WVPSVYC--TSPACKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTV 160
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
Q F E+V+EPG FV A+FDGILG+ +
Sbjct: 161 VGQQFGESVTEPGQTFVDAEFDGILGLGY 189
Score = 63.7 bits (148), Expect = 5e-10
Identities = 38/95 (40%), Positives = 54/95 (56%), Gaps = 10/95 (10%)
Frame = +3
Query: 105 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 254
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 255 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNL 359
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNL
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNL 102
>J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein.
Length = 396
Score = 94.3 bits (224), Expect = 3e-19
Identities = 45/89 (50%), Positives = 59/89 (66%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS C T+ AC H+++ +S TY G F+IQYG+GSLSG + D V+V GL V
Sbjct: 103 WVPSVYC--TSPACKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTV 160
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
Q F E+V+EPG FV A+FDGILG+ +
Sbjct: 161 VGQQFGESVTEPGQTFVDAEFDGILGLGY 189
Score = 63.7 bits (148), Expect = 5e-10
Identities = 38/95 (40%), Positives = 54/95 (56%), Gaps = 10/95 (10%)
Frame = +3
Query: 105 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 254
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 255 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNL 359
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNL
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNL 102
>BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein.
Length = 363
Score = 94.3 bits (224), Expect = 3e-19
Identities = 45/89 (50%), Positives = 59/89 (66%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS C T+ AC H+++ +S TY G F+IQYG+GSLSG + D V+V GL V
Sbjct: 103 WVPSVYC--TSPACKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTV 160
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
Q F E+V+EPG FV A+FDGILG+ +
Sbjct: 161 VGQQFGESVTEPGQTFVDAEFDGILGLGY 189
Score = 63.7 bits (148), Expect = 5e-10
Identities = 38/95 (40%), Positives = 54/95 (56%), Gaps = 10/95 (10%)
Frame = +3
Query: 105 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 254
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 255 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNL 359
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNL
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNL 102
>BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 94.3 bits (224), Expect = 3e-19
Identities = 45/89 (50%), Positives = 59/89 (66%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS C T+ AC H+++ +S TY G F+IQYG+GSLSG + D V+V GL V
Sbjct: 103 WVPSVYC--TSPACKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTV 160
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
Q F E+V+EPG FV A+FDGILG+ +
Sbjct: 161 VGQQFGESVTEPGQTFVDAEFDGILGLGY 189
Score = 63.7 bits (148), Expect = 5e-10
Identities = 38/95 (40%), Positives = 54/95 (56%), Gaps = 10/95 (10%)
Frame = +3
Query: 105 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 254
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 255 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNL 359
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNL
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNL 102
>BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 94.3 bits (224), Expect = 3e-19
Identities = 45/89 (50%), Positives = 59/89 (66%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS C T+ AC H+++ +S TY G F+IQYG+GSLSG + D V+V GL V
Sbjct: 103 WVPSVYC--TSPACKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTV 160
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
Q F E+V+EPG FV A+FDGILG+ +
Sbjct: 161 VGQQFGESVTEPGQTFVDAEFDGILGLGY 189
Score = 63.7 bits (148), Expect = 5e-10
Identities = 38/95 (40%), Positives = 54/95 (56%), Gaps = 10/95 (10%)
Frame = +3
Query: 105 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 254
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 255 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNL 359
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNL
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNL 102
>AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein.
Length = 396
Score = 94.3 bits (224), Expect = 3e-19
Identities = 45/89 (50%), Positives = 59/89 (66%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS C T+ AC H+++ +S TY G F+IQYG+GSLSG + D V+V GL V
Sbjct: 103 WVPSVYC--TSPACKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTV 160
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
Q F E+V+EPG FV A+FDGILG+ +
Sbjct: 161 VGQQFGESVTEPGQTFVDAEFDGILGLGY 189
Score = 63.7 bits (148), Expect = 5e-10
Identities = 38/95 (40%), Positives = 54/95 (56%), Gaps = 10/95 (10%)
Frame = +3
Query: 105 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 254
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 255 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNL 359
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNL
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNL 102
>AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternative
protein.
Length = 363
Score = 94.3 bits (224), Expect = 3e-19
Identities = 45/89 (50%), Positives = 59/89 (66%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS C T+ AC H+++ +S TY G F+IQYG+GSLSG + D V+V GL V
Sbjct: 103 WVPSVYC--TSPACKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTV 160
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
Q F E+V+EPG FV A+FDGILG+ +
Sbjct: 161 VGQQFGESVTEPGQTFVDAEFDGILGLGY 189
Score = 63.7 bits (148), Expect = 5e-10
Identities = 38/95 (40%), Positives = 54/95 (56%), Gaps = 10/95 (10%)
Frame = +3
Query: 105 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 254
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 255 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNL 359
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNL
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNL 102
>X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mRNA
fragment for renin (aa 105-401). ).
Length = 300
Score = 93.5 bits (222), Expect = 6e-19
Identities = 41/89 (46%), Positives = 57/89 (64%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS KC AC+ H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V
Sbjct: 4 WVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV 63
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
Q F E P L F+ A+FDG++GM F
Sbjct: 64 -TQMFGEVTEMPALPFMLAEFDGVVGMGF 91
>M26901-1|AAA60364.1| 403|Homo sapiens renin protein.
Length = 403
Score = 93.5 bits (222), Expect = 6e-19
Identities = 41/89 (46%), Positives = 57/89 (64%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS KC AC+ H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V
Sbjct: 111 WVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV 170
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
Q F E P L F+ A+FDG++GM F
Sbjct: 171 -TQMFGEVTEMPALPFMLAQFDGVVGMGF 198
Score = 62.5 bits (145), Expect = 1e-09
Identities = 26/33 (78%), Positives = 30/33 (90%)
Frame = +3
Query: 261 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNL 359
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNV 110
>M10152-1|AAD03461.1| 406|Homo sapiens renin protein.
Length = 406
Score = 93.5 bits (222), Expect = 6e-19
Identities = 41/89 (46%), Positives = 57/89 (64%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS KC AC+ H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V
Sbjct: 111 WVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV 170
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
Q F E P L F+ A+FDG++GM F
Sbjct: 171 -TQMFGEVTEMPALPFMLAEFDGVVGMGF 198
Score = 62.5 bits (145), Expect = 1e-09
Identities = 26/33 (78%), Positives = 30/33 (90%)
Frame = +3
Query: 261 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNL 359
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNV 110
>L00073-1|AAA60363.1| 406|Homo sapiens renin protein.
Length = 406
Score = 93.5 bits (222), Expect = 6e-19
Identities = 41/89 (46%), Positives = 57/89 (64%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS KC AC+ H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V
Sbjct: 111 WVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV 170
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
Q F E P L F+ A+FDG++GM F
Sbjct: 171 -TQMFGEVTEMPALPFMLAEFDGVVGMGF 198
Score = 62.5 bits (145), Expect = 1e-09
Identities = 26/33 (78%), Positives = 30/33 (90%)
Frame = +3
Query: 261 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNL 359
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNV 110
>CR536498-1|CAG38737.1| 406|Homo sapiens REN protein.
Length = 406
Score = 93.5 bits (222), Expect = 6e-19
Identities = 41/89 (46%), Positives = 57/89 (64%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS KC AC+ H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V
Sbjct: 111 WVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV 170
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
Q F E P L F+ A+FDG++GM F
Sbjct: 171 -TQMFGEVTEMPALPFMLAEFDGVVGMGF 198
Score = 62.5 bits (145), Expect = 1e-09
Identities = 26/33 (78%), Positives = 30/33 (90%)
Frame = +3
Query: 261 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNL 359
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNV 110
>BC047752-1|AAH47752.1| 406|Homo sapiens renin protein.
Length = 406
Score = 93.5 bits (222), Expect = 6e-19
Identities = 41/89 (46%), Positives = 57/89 (64%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS KC AC+ H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V
Sbjct: 111 WVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV 170
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
Q F E P L F+ A+FDG++GM F
Sbjct: 171 -TQMFGEVTEMPALPFMLAEFDGVVGMGF 198
Score = 62.5 bits (145), Expect = 1e-09
Identities = 26/33 (78%), Positives = 30/33 (90%)
Frame = +3
Query: 261 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNL 359
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNV 110
>BC033474-1|AAH33474.1| 406|Homo sapiens renin protein.
Length = 406
Score = 93.5 bits (222), Expect = 6e-19
Identities = 41/89 (46%), Positives = 57/89 (64%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS KC AC+ H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V
Sbjct: 111 WVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV 170
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
Q F E P L F+ A+FDG++GM F
Sbjct: 171 -TQMFGEVTEMPALPFMLAEFDGVVGMGF 198
Score = 62.5 bits (145), Expect = 1e-09
Identities = 26/33 (78%), Positives = 30/33 (90%)
Frame = +3
Query: 261 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNL 359
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNV 110
>AY436324-1|AAR03502.1| 403|Homo sapiens renin protein.
Length = 403
Score = 93.5 bits (222), Expect = 6e-19
Identities = 41/89 (46%), Positives = 57/89 (64%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS KC AC+ H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V
Sbjct: 111 WVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV 170
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
Q F E P L F+ A+FDG++GM F
Sbjct: 171 -TQMFGEVTEMPALPFMLAEFDGVVGMGF 198
Score = 62.5 bits (145), Expect = 1e-09
Identities = 26/33 (78%), Positives = 30/33 (90%)
Frame = +3
Query: 261 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNL 359
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNV 110
>AL592146-1|CAI16594.1| 406|Homo sapiens renin protein.
Length = 406
Score = 93.5 bits (222), Expect = 6e-19
Identities = 41/89 (46%), Positives = 57/89 (64%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS KC AC+ H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V
Sbjct: 111 WVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV 170
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
Q F E P L F+ A+FDG++GM F
Sbjct: 171 -TQMFGEVTEMPALPFMLAEFDGVVGMGF 198
Score = 62.5 bits (145), Expect = 1e-09
Identities = 26/33 (78%), Positives = 30/33 (90%)
Frame = +3
Query: 261 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNL 359
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNV 110
>AL592114-1|CAH71224.1| 406|Homo sapiens renin protein.
Length = 406
Score = 93.5 bits (222), Expect = 6e-19
Identities = 41/89 (46%), Positives = 57/89 (64%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS KC AC+ H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V
Sbjct: 111 WVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV 170
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
Q F E P L F+ A+FDG++GM F
Sbjct: 171 -TQMFGEVTEMPALPFMLAEFDGVVGMGF 198
Score = 62.5 bits (145), Expect = 1e-09
Identities = 26/33 (78%), Positives = 30/33 (90%)
Frame = +3
Query: 261 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNL 359
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNV 110
>U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein.
Length = 388
Score = 89.4 bits (212), Expect = 9e-18
Identities = 41/89 (46%), Positives = 59/89 (66%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS C + AC H++++ +S TY NG F++QYGSGSL+GF D +TV ++V
Sbjct: 98 WVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQV 155
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
Q F + +EPG FV A+FDGI+G+A+
Sbjct: 156 PNQEFGLSENEPGTNFVYAQFDGIMGLAY 184
Score = 63.3 bits (147), Expect = 7e-10
Identities = 39/82 (47%), Positives = 50/82 (60%), Gaps = 9/82 (10%)
Frame = +3
Query: 141 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 293
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 294 VISIGTPPQSFKVVFDTGSSNL 359
ISIGTPPQ+F V+FDTGSSNL
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNL 97
>M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein.
Length = 388
Score = 89.4 bits (212), Expect = 9e-18
Identities = 41/89 (46%), Positives = 59/89 (66%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS C + AC H++++ +S TY NG F++QYGSGSL+GF D +TV ++V
Sbjct: 98 WVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQV 155
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
Q F + +EPG FV A+FDGI+G+A+
Sbjct: 156 PNQEFGLSENEPGTNFVYAQFDGIMGLAY 184
Score = 63.3 bits (147), Expect = 7e-10
Identities = 39/82 (47%), Positives = 50/82 (60%), Gaps = 9/82 (10%)
Frame = +3
Query: 141 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 293
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 294 VISIGTPPQSFKVVFDTGSSNL 359
ISIGTPPQ+F V+FDTGSSNL
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNL 97
>M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein.
Length = 385
Score = 89.4 bits (212), Expect = 9e-18
Identities = 41/89 (46%), Positives = 59/89 (66%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS C + AC H++++ +S TY NG F++QYGSGSL+GF D +TV ++V
Sbjct: 95 WVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQV 152
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
Q F + +EPG FV A+FDGI+G+A+
Sbjct: 153 PNQEFGLSENEPGTNFVYAQFDGIMGLAY 181
Score = 63.3 bits (147), Expect = 7e-10
Identities = 39/82 (47%), Positives = 50/82 (60%), Gaps = 9/82 (10%)
Frame = +3
Query: 141 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 293
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 14 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 72
Query: 294 VISIGTPPQSFKVVFDTGSSNL 359
ISIGTPPQ+F V+FDTGSSNL
Sbjct: 73 EISIGTPPQNFLVLFDTGSSNL 94
>J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein.
Length = 388
Score = 89.4 bits (212), Expect = 9e-18
Identities = 41/89 (46%), Positives = 59/89 (66%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS C + AC H++++ +S TY NG F++QYGSGSL+GF D +TV ++V
Sbjct: 98 WVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQV 155
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
Q F + +EPG FV A+FDGI+G+A+
Sbjct: 156 PNQEFGLSENEPGTNFVYAQFDGIMGLAY 184
Score = 63.3 bits (147), Expect = 7e-10
Identities = 39/82 (47%), Positives = 50/82 (60%), Gaps = 9/82 (10%)
Frame = +3
Query: 141 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 293
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 294 VISIGTPPQSFKVVFDTGSSNL 359
ISIGTPPQ+F V+FDTGSSNL
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNL 97
>BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 89.4 bits (212), Expect = 9e-18
Identities = 41/89 (46%), Positives = 59/89 (66%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS C + AC H++++ +S TY NG F++QYGSGSL+GF D +TV ++V
Sbjct: 98 WVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQV 155
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
Q F + +EPG FV A+FDGI+G+A+
Sbjct: 156 PNQEFGLSENEPGTNFVYAQFDGIMGLAY 184
Score = 63.3 bits (147), Expect = 7e-10
Identities = 39/82 (47%), Positives = 50/82 (60%), Gaps = 9/82 (10%)
Frame = +3
Query: 141 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 293
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 294 VISIGTPPQSFKVVFDTGSSNL 359
ISIGTPPQ+F V+FDTGSSNL
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNL 97
>AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 89.4 bits (212), Expect = 9e-18
Identities = 41/89 (46%), Positives = 59/89 (66%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS C + AC H++++ +S TY NG F++QYGSGSL+GF D +TV ++V
Sbjct: 98 WVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQV 155
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
Q F + +EPG FV A+FDGI+G+A+
Sbjct: 156 PNQEFGLSENEPGTNFVYAQFDGIMGLAY 184
Score = 63.3 bits (147), Expect = 7e-10
Identities = 39/82 (47%), Positives = 50/82 (60%), Gaps = 9/82 (10%)
Frame = +3
Query: 141 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 293
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 294 VISIGTPPQSFKVVFDTGSSNL 359
ISIGTPPQ+F V+FDTGSSNL
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNL 97
>M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein.
Length = 388
Score = 78.2 bits (184), Expect = 2e-14
Identities = 37/89 (41%), Positives = 53/89 (59%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS C +++AC HN+++ S TY + +I YG+GS++G L D V VGG+
Sbjct: 101 WVPSVYC--SSLACTNHNRFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISD 158
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
Q F + +EPG A FDGILG+A+
Sbjct: 159 TNQIFGLSETEPGSFLYYAPFDGILGLAY 187
Score = 68.5 bits (160), Expect = 2e-11
Identities = 42/97 (43%), Positives = 53/97 (54%), Gaps = 12/97 (12%)
Frame = +3
Query: 105 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 254
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSFRRTLSERGLLKDFLKKHNLNPARKYFPQWKAPTLV 63
Query: 255 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNL 359
+PL NYLD +Y+G I IGTP Q F V+FDTGSSNL
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVLFDTGSSNL 100
>J00287-1|AAA98529.1| 388|Homo sapiens PEP protein.
Length = 388
Score = 78.2 bits (184), Expect = 2e-14
Identities = 37/89 (41%), Positives = 53/89 (59%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS C +++AC HN+++ S TY + +I YG+GS++G L D V VGG+
Sbjct: 101 WVPSVYC--SSLACTNHNRFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISD 158
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
Q F + +EPG A FDGILG+A+
Sbjct: 159 TNQIFGLSETEPGSFLYYAPFDGILGLAY 187
Score = 70.1 bits (164), Expect = 6e-12
Identities = 43/97 (44%), Positives = 53/97 (54%), Gaps = 12/97 (12%)
Frame = +3
Query: 105 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 254
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 255 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNL 359
+PL NYLD +Y+G I IGTP Q F VVFDTGSSNL
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNL 100
>BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I
(pepsinogen A) protein.
Length = 388
Score = 78.2 bits (184), Expect = 2e-14
Identities = 37/89 (41%), Positives = 53/89 (59%)
Frame = +1
Query: 361 WVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 540
WVPS C +++AC HN+++ S TY + +I YG+GS++G L D V VGG+
Sbjct: 101 WVPSVYC--SSLACTNHNRFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISD 158
Query: 541 RRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
Q F + +EPG A FDGILG+A+
Sbjct: 159 TNQIFGLSETEPGSFLYYAPFDGILGLAY 187
Score = 70.1 bits (164), Expect = 6e-12
Identities = 43/97 (44%), Positives = 53/97 (54%), Gaps = 12/97 (12%)
Frame = +3
Query: 105 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 254
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 255 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNL 359
+PL NYLD +Y+G I IGTP Q F VVFDTGSSNL
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNL 100
>BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein.
Length = 104
Score = 60.1 bits (139), Expect = 6e-09
Identities = 38/82 (46%), Positives = 49/82 (59%), Gaps = 9/82 (10%)
Frame = +3
Query: 141 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 293
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 294 VISIGTPPQSFKVVFDTGSSNL 359
ISIGTPPQ+F V+FDTGSS L
Sbjct: 76 EISIGTPPQNFLVLFDTGSSPL 97
>AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens
cDNA PSEC0239 fis, clone OVARC1000363, highly similar to
Homo sapiens aspartyl protease mRNA. ).
Length = 423
Score = 39.5 bits (88), Expect = 0.010
Identities = 22/72 (30%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Frame = +1
Query: 418 YDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV- 591
+D+ +S TY + G ++Y GS +GF+ D VT+ G + E G F+
Sbjct: 35 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESGNFFLP 94
Query: 592 AAKFDGILGMAF 627
+++GILG+A+
Sbjct: 95 GIQWNGILGLAY 106
Score = 31.9 bits (69), Expect = 1.9
Identities = 12/18 (66%), Positives = 15/18 (83%)
Frame = +3
Query: 303 IGTPPQSFKVVFDTGSSN 356
IGTPPQ +++ DTGSSN
Sbjct: 3 IGTPPQKLQILVDTGSSN 20
>AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 86
Score = 38.7 bits (86), Expect = 0.017
Identities = 28/70 (40%), Positives = 37/70 (52%), Gaps = 9/70 (12%)
Frame = +3
Query: 132 SVMALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 284
+V+ RVPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 18 AVICKQRVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 76
Query: 285 YYGVISIGTP 314
Y+G ISIGTP
Sbjct: 77 YFGEISIGTP 86
>BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving
enzyme 2 protein.
Length = 518
Score = 37.9 bits (84), Expect = 0.029
Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Frame = +1
Query: 418 YDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV- 591
+D+ +S TY + G ++Y GS +GF+ D VT+ G + E F+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLP 189
Query: 592 AAKFDGILGMAF 627
K++GILG+A+
Sbjct: 190 GIKWNGILGLAY 201
Score = 34.7 bits (76), Expect = 0.27
Identities = 14/24 (58%), Positives = 18/24 (75%)
Frame = +3
Query: 285 YYGVISIGTPPQSFKVVFDTGSSN 356
YY + IGTPPQ +++ DTGSSN
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSN 115
>AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein.
Length = 518
Score = 37.9 bits (84), Expect = 0.029
Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Frame = +1
Query: 418 YDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV- 591
+D+ +S TY + G ++Y GS +GF+ D VT+ G + E F+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLP 189
Query: 592 AAKFDGILGMAF 627
K++GILG+A+
Sbjct: 190 GIKWNGILGLAY 201
Score = 34.7 bits (76), Expect = 0.27
Identities = 14/24 (58%), Positives = 18/24 (75%)
Frame = +3
Query: 285 YYGVISIGTPPQSFKVVFDTGSSN 356
YY + IGTPPQ +++ DTGSSN
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSN 115
>AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving
enzyme 2, EC 3.4.23. protein.
Length = 415
Score = 37.9 bits (84), Expect = 0.029
Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Frame = +1
Query: 418 YDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV- 591
+D+ +S TY + G ++Y GS +GF+ D VT+ G + E F+
Sbjct: 27 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLP 86
Query: 592 AAKFDGILGMAF 627
K++GILG+A+
Sbjct: 87 GIKWNGILGLAY 98
>AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein.
Length = 439
Score = 37.9 bits (84), Expect = 0.029
Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Frame = +1
Query: 418 YDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV- 591
+D+ +S TY + G ++Y GS +GF+ D VT+ G + E F+
Sbjct: 51 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLP 110
Query: 592 AAKFDGILGMAF 627
K++GILG+A+
Sbjct: 111 GIKWNGILGLAY 122
Score = 34.7 bits (76), Expect = 0.27
Identities = 14/24 (58%), Positives = 18/24 (75%)
Frame = +3
Query: 285 YYGVISIGTPPQSFKVVFDTGSSN 356
YY + IGTPPQ +++ DTGSSN
Sbjct: 13 YYLEMLIGTPPQKLQILVDTGSSN 36
>AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic
proteinase Asp 1 protein.
Length = 518
Score = 37.9 bits (84), Expect = 0.029
Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Frame = +1
Query: 418 YDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV- 591
+D+ +S TY + G ++Y GS +GF+ D VT+ G + E F+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLP 189
Query: 592 AAKFDGILGMAF 627
K++GILG+A+
Sbjct: 190 GIKWNGILGLAY 201
Score = 34.7 bits (76), Expect = 0.27
Identities = 14/24 (58%), Positives = 18/24 (75%)
Frame = +3
Query: 285 YYGVISIGTPPQSFKVVFDTGSSN 356
YY + IGTPPQ +++ DTGSSN
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSN 115
>AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1
protein.
Length = 518
Score = 37.9 bits (84), Expect = 0.029
Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Frame = +1
Query: 418 YDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV- 591
+D+ +S TY + G ++Y GS +GF+ D VT+ G + E F+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLP 189
Query: 592 AAKFDGILGMAF 627
K++GILG+A+
Sbjct: 190 GIKWNGILGLAY 201
Score = 34.7 bits (76), Expect = 0.27
Identities = 14/24 (58%), Positives = 18/24 (75%)
Frame = +3
Query: 285 YYGVISIGTPPQSFKVVFDTGSSN 356
YY + IGTPPQ +++ DTGSSN
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSN 115
>AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein.
Length = 518
Score = 37.9 bits (84), Expect = 0.029
Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Frame = +1
Query: 418 YDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV- 591
+D+ +S TY + G ++Y GS +GF+ D VT+ G + E F+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLP 189
Query: 592 AAKFDGILGMAF 627
K++GILG+A+
Sbjct: 190 GIKWNGILGLAY 201
Score = 34.7 bits (76), Expect = 0.27
Identities = 14/24 (58%), Positives = 18/24 (75%)
Frame = +3
Query: 285 YYGVISIGTPPQSFKVVFDTGSSN 356
YY + IGTPPQ +++ DTGSSN
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSN 115
>AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein.
Length = 396
Score = 37.9 bits (84), Expect = 0.029
Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Frame = +1
Query: 418 YDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV- 591
+D+ +S TY + G ++Y GS +GF+ D VT+ G + E F+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLP 189
Query: 592 AAKFDGILGMAF 627
K++GILG+A+
Sbjct: 190 GIKWNGILGLAY 201
Score = 34.7 bits (76), Expect = 0.27
Identities = 14/24 (58%), Positives = 18/24 (75%)
Frame = +3
Query: 285 YYGVISIGTPPQSFKVVFDTGSSN 356
YY + IGTPPQ +++ DTGSSN
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSN 115
>AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein.
Length = 468
Score = 37.9 bits (84), Expect = 0.029
Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Frame = +1
Query: 418 YDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV- 591
+D+ +S TY + G ++Y GS +GF+ D VT+ G + E F+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLP 189
Query: 592 AAKFDGILGMAF 627
K++GILG+A+
Sbjct: 190 GIKWNGILGLAY 201
Score = 34.7 bits (76), Expect = 0.27
Identities = 14/24 (58%), Positives = 18/24 (75%)
Frame = +3
Query: 285 YYGVISIGTPPQSFKVVFDTGSSN 356
YY + IGTPPQ +++ DTGSSN
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSN 115
>AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 37.9 bits (84), Expect = 0.029
Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Frame = +1
Query: 418 YDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV- 591
+D+ +S TY + G ++Y GS +GF+ D VT+ G + E F+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLP 189
Query: 592 AAKFDGILGMAF 627
K++GILG+A+
Sbjct: 190 GIKWNGILGLAY 201
Score = 34.7 bits (76), Expect = 0.27
Identities = 14/24 (58%), Positives = 18/24 (75%)
Frame = +3
Query: 285 YYGVISIGTPPQSFKVVFDTGSSN 356
YY + IGTPPQ +++ DTGSSN
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSN 115
>AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease
protein.
Length = 518
Score = 37.9 bits (84), Expect = 0.029
Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Frame = +1
Query: 418 YDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV- 591
+D+ +S TY + G ++Y GS +GF+ D VT+ G + E F+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLP 189
Query: 592 AAKFDGILGMAF 627
K++GILG+A+
Sbjct: 190 GIKWNGILGLAY 201
Score = 34.7 bits (76), Expect = 0.27
Identities = 14/24 (58%), Positives = 18/24 (75%)
Frame = +3
Query: 285 YYGVISIGTPPQSFKVVFDTGSSN 356
YY + IGTPPQ +++ DTGSSN
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSN 115
>AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 37.9 bits (84), Expect = 0.029
Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Frame = +1
Query: 418 YDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV- 591
+D+ +S TY + G ++Y GS +GF+ D VT+ G + E F+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLP 189
Query: 592 AAKFDGILGMAF 627
K++GILG+A+
Sbjct: 190 GIKWNGILGLAY 201
Score = 34.7 bits (76), Expect = 0.27
Identities = 14/24 (58%), Positives = 18/24 (75%)
Frame = +3
Query: 285 YYGVISIGTPPQSFKVVFDTGSSN 356
YY + IGTPPQ +++ DTGSSN
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSN 115
>AL365205-2|CAI95135.1| 140|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 140
Score = 36.7 bits (81), Expect = 0.067
Identities = 16/35 (45%), Positives = 24/35 (68%)
Frame = +1
Query: 523 VGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAF 627
V ++V Q F + +EPG FV A+FDGI+G+A+
Sbjct: 71 VQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAY 105
>DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 36.3 bits (80), Expect = 0.089
Identities = 16/38 (42%), Positives = 26/38 (68%), Gaps = 1/38 (2%)
Frame = +3
Query: 285 YYGVISIGTPPQSFKVVFDTGSSNL-LGAFQKVPLHQH 395
YY +++G+PPQ+ ++ DTGSSN +GA LH++
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 112
>BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 36.3 bits (80), Expect = 0.089
Identities = 16/38 (42%), Positives = 26/38 (68%), Gaps = 1/38 (2%)
Frame = +3
Query: 285 YYGVISIGTPPQSFKVVFDTGSSNL-LGAFQKVPLHQH 395
YY +++G+PPQ+ ++ DTGSSN +GA LH++
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 112
>BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 36.3 bits (80), Expect = 0.089
Identities = 16/38 (42%), Positives = 26/38 (68%), Gaps = 1/38 (2%)
Frame = +3
Query: 285 YYGVISIGTPPQSFKVVFDTGSSNL-LGAFQKVPLHQH 395
YY +++G+PPQ+ ++ DTGSSN +GA LH++
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 112
>AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving
enzyme type C protein.
Length = 457
Score = 36.3 bits (80), Expect = 0.089
Identities = 16/38 (42%), Positives = 26/38 (68%), Gaps = 1/38 (2%)
Frame = +3
Query: 285 YYGVISIGTPPQSFKVVFDTGSSNL-LGAFQKVPLHQH 395
YY +++G+PPQ+ ++ DTGSSN +GA LH++
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 112
>AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving
enzyme type B protein.
Length = 476
Score = 36.3 bits (80), Expect = 0.089
Identities = 16/38 (42%), Positives = 26/38 (68%), Gaps = 1/38 (2%)
Frame = +3
Query: 285 YYGVISIGTPPQSFKVVFDTGSSNL-LGAFQKVPLHQH 395
YY +++G+PPQ+ ++ DTGSSN +GA LH++
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 112
>AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic
proteinase Asp 2 protein.
Length = 501
Score = 36.3 bits (80), Expect = 0.089
Identities = 16/38 (42%), Positives = 26/38 (68%), Gaps = 1/38 (2%)
Frame = +3
Query: 285 YYGVISIGTPPQSFKVVFDTGSSNL-LGAFQKVPLHQH 395
YY +++G+PPQ+ ++ DTGSSN +GA LH++
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 112
>AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase
protein.
Length = 501
Score = 36.3 bits (80), Expect = 0.089
Identities = 16/38 (42%), Positives = 26/38 (68%), Gaps = 1/38 (2%)
Frame = +3
Query: 285 YYGVISIGTPPQSFKVVFDTGSSNL-LGAFQKVPLHQH 395
YY +++G+PPQ+ ++ DTGSSN +GA LH++
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 112
>AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2
protein.
Length = 501
Score = 36.3 bits (80), Expect = 0.089
Identities = 16/38 (42%), Positives = 26/38 (68%), Gaps = 1/38 (2%)
Frame = +3
Query: 285 YYGVISIGTPPQSFKVVFDTGSSNL-LGAFQKVPLHQH 395
YY +++G+PPQ+ ++ DTGSSN +GA LH++
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 112
>AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein.
Length = 488
Score = 36.3 bits (80), Expect = 0.089
Identities = 16/38 (42%), Positives = 26/38 (68%), Gaps = 1/38 (2%)
Frame = +3
Query: 285 YYGVISIGTPPQSFKVVFDTGSSNL-LGAFQKVPLHQH 395
YY +++G+PPQ+ ++ DTGSSN +GA LH++
Sbjct: 62 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 99
>AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving
enzyme protein.
Length = 501
Score = 36.3 bits (80), Expect = 0.089
Identities = 16/38 (42%), Positives = 26/38 (68%), Gaps = 1/38 (2%)
Frame = +3
Query: 285 YYGVISIGTPPQSFKVVFDTGSSNL-LGAFQKVPLHQH 395
YY +++G+PPQ+ ++ DTGSSN +GA LH++
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 112
>AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving
enzyme isoform I-127 protein.
Length = 127
Score = 36.3 bits (80), Expect = 0.089
Identities = 16/38 (42%), Positives = 26/38 (68%), Gaps = 1/38 (2%)
Frame = +3
Query: 285 YYGVISIGTPPQSFKVVFDTGSSNL-LGAFQKVPLHQH 395
YY +++G+PPQ+ ++ DTGSSN +GA LH++
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 112
>AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving
enzyme I-432 protein.
Length = 432
Score = 36.3 bits (80), Expect = 0.089
Identities = 16/38 (42%), Positives = 26/38 (68%), Gaps = 1/38 (2%)
Frame = +3
Query: 285 YYGVISIGTPPQSFKVVFDTGSSNL-LGAFQKVPLHQH 395
YY +++G+PPQ+ ++ DTGSSN +GA LH++
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 112
>AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving
enzyme I-457 protein.
Length = 457
Score = 36.3 bits (80), Expect = 0.089
Identities = 16/38 (42%), Positives = 26/38 (68%), Gaps = 1/38 (2%)
Frame = +3
Query: 285 YYGVISIGTPPQSFKVVFDTGSSNL-LGAFQKVPLHQH 395
YY +++G+PPQ+ ++ DTGSSN +GA LH++
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 112
>AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving
enzyme I-476 protein.
Length = 476
Score = 36.3 bits (80), Expect = 0.089
Identities = 16/38 (42%), Positives = 26/38 (68%), Gaps = 1/38 (2%)
Frame = +3
Query: 285 YYGVISIGTPPQSFKVVFDTGSSNL-LGAFQKVPLHQH 395
YY +++G+PPQ+ ++ DTGSSN +GA LH++
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 112
>AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein.
Length = 532
Score = 36.3 bits (80), Expect = 0.089
Identities = 16/38 (42%), Positives = 26/38 (68%), Gaps = 1/38 (2%)
Frame = +3
Query: 285 YYGVISIGTPPQSFKVVFDTGSSNL-LGAFQKVPLHQH 395
YY +++G+PPQ+ ++ DTGSSN +GA LH++
Sbjct: 106 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 143
>AF141344-1|AAG49447.1| 119|Homo sapiens LYST-interacting protein
LIP8 protein.
Length = 119
Score = 32.3 bits (70), Expect = 1.4
Identities = 13/33 (39%), Positives = 16/33 (48%)
Frame = -1
Query: 508 WRGSRRGCRSRTVSRTGCHSRRTSWTCGCRTCC 410
W GS+R C + V + S SW CR CC
Sbjct: 8 WPGSKRECANCRVGTSSWRSSGWSWWKDCRPCC 40
>AK055141-1|BAB70862.1| 260|Homo sapiens protein ( Homo sapiens
cDNA FLJ30579 fis, clone BRAWH2006989, weakly similar to
DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (EC
2.7.7.6). ).
Length = 260
Score = 31.9 bits (69), Expect = 1.9
Identities = 17/35 (48%), Positives = 18/35 (51%)
Frame = -1
Query: 517 HHQWRGSRRGCRSRTVSRTGCHSRRTSWTCGCRTC 413
H+ W GS R C S T S G HS SWT R C
Sbjct: 26 HNSWTGSNRACSSWTGSTRG-HS---SWTGSSRAC 56
>BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain
containing 11 protein.
Length = 514
Score = 30.7 bits (66), Expect = 4.4
Identities = 12/26 (46%), Positives = 18/26 (69%)
Frame = -3
Query: 350 GSGVEYHLERLRRRADTDHSVVLSIK 273
G G E+HLER+RR ++++ SIK
Sbjct: 30 GQGAEHHLERIRRSHQKHNAILASIK 55
>BC133035-1|AAI33036.1| 129|Homo sapiens keratin associated protein
5-6 protein.
Length = 129
Score = 30.3 bits (65), Expect = 5.8
Identities = 17/40 (42%), Positives = 20/40 (50%)
Frame = -1
Query: 502 GSRRGCRSRTVSRTGCHSRRTSWTCGCRTCCAANKRCWCS 383
GS+ GC S S+ GC S CGC C K C+CS
Sbjct: 65 GSKGGCGSCGGSKGGCGS------CGCSQCSCC-KPCYCS 97
>BC130399-1|AAI30400.1| 129|Homo sapiens keratin associated protein
5-6 protein.
Length = 129
Score = 30.3 bits (65), Expect = 5.8
Identities = 17/40 (42%), Positives = 20/40 (50%)
Frame = -1
Query: 502 GSRRGCRSRTVSRTGCHSRRTSWTCGCRTCCAANKRCWCS 383
GS+ GC S S+ GC S CGC C K C+CS
Sbjct: 65 GSKGGCGSCGGSKGGCGS------CGCSQCSCC-KPCYCS 97
>AB126075-1|BAD20202.1| 129|Homo sapiens keratin associated protein
protein.
Length = 129
Score = 30.3 bits (65), Expect = 5.8
Identities = 17/40 (42%), Positives = 20/40 (50%)
Frame = -1
Query: 502 GSRRGCRSRTVSRTGCHSRRTSWTCGCRTCCAANKRCWCS 383
GS+ GC S S+ GC S CGC C K C+CS
Sbjct: 65 GSKGGCGSCGGSKGGCGS------CGCSQCSCC-KPCYCS 97
>X85133-1|CAA59445.1| 948|Homo sapiens RB protein binding protein
protein.
Length = 948
Score = 29.9 bits (64), Expect = 7.7
Identities = 16/46 (34%), Positives = 21/46 (45%)
Frame = -3
Query: 617 PRIPSNLAATKASPGSDTASANVWRRTLSPPTVTSSVERKPERLPE 480
P P+NL+ S G TA +N T +PP R+ RL E
Sbjct: 429 PPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKE 474
>AY072922-1|AAL68925.1| 1625|Homo sapiens p53-associated cellular
protein PACT protein.
Length = 1625
Score = 29.9 bits (64), Expect = 7.7
Identities = 16/46 (34%), Positives = 21/46 (45%)
Frame = -3
Query: 617 PRIPSNLAATKASPGSDTASANVWRRTLSPPTVTSSVERKPERLPE 480
P P+NL+ S G TA +N T +PP R+ RL E
Sbjct: 472 PPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKE 517
>AF352051-1|AAL05625.1| 1616|Homo sapiens proliferation
potential-related protein protein.
Length = 1616
Score = 29.9 bits (64), Expect = 7.7
Identities = 16/46 (34%), Positives = 21/46 (45%)
Frame = -3
Query: 617 PRIPSNLAATKASPGSDTASANVWRRTLSPPTVTSSVERKPERLPE 480
P P+NL+ S G TA +N T +PP R+ RL E
Sbjct: 429 PPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKE 474
>AB112075-1|BAC77637.1| 1758|Homo sapiens retinoblastoma binding
protein 6 isoform 2 protein.
Length = 1758
Score = 29.9 bits (64), Expect = 7.7
Identities = 16/46 (34%), Positives = 21/46 (45%)
Frame = -3
Query: 617 PRIPSNLAATKASPGSDTASANVWRRTLSPPTVTSSVERKPERLPE 480
P P+NL+ S G TA +N T +PP R+ RL E
Sbjct: 605 PPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKE 650
>AB112074-1|BAC77636.1| 1792|Homo sapiens retinoblastoma binding
protein 6 isoform 1 protein.
Length = 1792
Score = 29.9 bits (64), Expect = 7.7
Identities = 16/46 (34%), Positives = 21/46 (45%)
Frame = -3
Query: 617 PRIPSNLAATKASPGSDTASANVWRRTLSPPTVTSSVERKPERLPE 480
P P+NL+ S G TA +N T +PP R+ RL E
Sbjct: 605 PPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKE 650
>BC146666-1|AAI46667.1| 689|Homo sapiens SLC34A2 protein protein.
Length = 689
Score = 24.2 bits (50), Expect(2) = 9.4
Identities = 7/13 (53%), Positives = 8/13 (61%)
Frame = -1
Query: 430 CGCRTCCAANKRC 392
CGC CC +K C
Sbjct: 632 CGCPKCCRCSKCC 644
Score = 23.8 bits (49), Expect(2) = 9.4
Identities = 10/20 (50%), Positives = 10/20 (50%)
Frame = -1
Query: 463 TGCHSRRTSWTCGCRTCCAA 404
TGC R C CR CC A
Sbjct: 610 TGCFQMRCC--CCCRVCCRA 627
>BC142704-1|AAI42705.1| 689|Homo sapiens SLC34A2 protein protein.
Length = 689
Score = 24.2 bits (50), Expect(2) = 9.4
Identities = 7/13 (53%), Positives = 8/13 (61%)
Frame = -1
Query: 430 CGCRTCCAANKRC 392
CGC CC +K C
Sbjct: 632 CGCPKCCRCSKCC 644
Score = 23.8 bits (49), Expect(2) = 9.4
Identities = 10/20 (50%), Positives = 10/20 (50%)
Frame = -1
Query: 463 TGCHSRRTSWTCGCRTCCAA 404
TGC R C CR CC A
Sbjct: 610 TGCFQMRCC--CCCRVCCRA 627
>AF146796-1|AAF31328.1| 689|Homo sapiens sodium dependent phosphate
transporter isoform NaPi-IIb protein.
Length = 689
Score = 24.2 bits (50), Expect(2) = 9.4
Identities = 7/13 (53%), Positives = 8/13 (61%)
Frame = -1
Query: 430 CGCRTCCAANKRC 392
CGC CC +K C
Sbjct: 632 CGCPKCCRCSKCC 644
Score = 23.8 bits (49), Expect(2) = 9.4
Identities = 10/20 (50%), Positives = 10/20 (50%)
Frame = -1
Query: 463 TGCHSRRTSWTCGCRTCCAA 404
TGC R C CR CC A
Sbjct: 610 TGCFQMRCC--CCCRVCCRA 627
>AK075015-1|BAC11354.1| 397|Homo sapiens protein ( Homo sapiens
cDNA FLJ90534 fis, clone OVARC1000003, highly similar to
Homo sapiens sodium dependent phosphate transporter
isoform ).
Length = 397
Score = 24.2 bits (50), Expect(2) = 9.9
Identities = 7/13 (53%), Positives = 8/13 (61%)
Frame = -1
Query: 430 CGCRTCCAANKRC 392
CGC CC +K C
Sbjct: 340 CGCPKCCRCSKCC 352
Score = 23.8 bits (49), Expect(2) = 9.9
Identities = 10/20 (50%), Positives = 10/20 (50%)
Frame = -1
Query: 463 TGCHSRRTSWTCGCRTCCAA 404
TGC R C CR CC A
Sbjct: 318 TGCFQMRCC--CCCRVCCRA 335
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 92,677,749
Number of Sequences: 237096
Number of extensions: 2040018
Number of successful extensions: 6079
Number of sequences better than 10.0: 85
Number of HSP's better than 10.0 without gapping: 5504
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6041
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6804036910
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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