Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= epV31235
(694 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AL513122-4|CAI14414.1| 228|Homo sapiens gelsolin (amyloidosis, ... 219 1e-56
X04412-1|CAA28000.1| 782|Homo sapiens plasma gelsolin protein. 218 2e-56
BC026033-1|AAH26033.1| 782|Homo sapiens gelsolin (amyloidosis, ... 218 2e-56
AL513122-6|CAM20459.1| 731|Homo sapiens gelsolin (amyloidosis, ... 218 2e-56
AL513122-5|CAI14415.1| 260|Homo sapiens gelsolin (amyloidosis, ... 218 2e-56
AL513122-3|CAI14413.1| 782|Homo sapiens gelsolin (amyloidosis, ... 218 2e-56
AF276507-1|AAK60494.1| 715|Homo sapiens scinderin protein. 195 1e-49
AC005281-1|AAD15423.1| 527|Homo sapiens WUGSC:H_DJ0722F20.1 pro... 195 1e-49
AB067492-1|BAB67798.1| 626|Homo sapiens KIAA1905 protein protein. 195 1e-49
BC021090-1|AAH21090.1| 715|Homo sapiens SCIN protein protein. 194 2e-49
AK075123-1|BAC11416.1| 715|Homo sapiens protein ( Homo sapiens ... 194 3e-49
AF041449-1|AAC25051.1| 819|Homo sapiens advillin protein. 190 3e-48
X12901-1|CAA31386.1| 827|Homo sapiens protein ( Human mRNA for ... 179 8e-45
BC017303-1|AAH17303.1| 421|Homo sapiens VIL1 protein protein. 179 8e-45
AK223398-1|BAD97118.1| 827|Homo sapiens villin 1 variant protein. 179 8e-45
BC111730-1|AAI11731.1| 812|Homo sapiens AVIL protein protein. 177 4e-44
M94345-1|AAA59570.1| 348|Homo sapiens macrophage capping protei... 160 4e-39
BC014549-1|AAH14549.1| 348|Homo sapiens capping protein (actin ... 160 4e-39
BC000728-1|AAH00728.1| 348|Homo sapiens capping protein (actin ... 160 4e-39
AC062037-3|AAY24128.1| 348|Homo sapiens unknown protein. 160 4e-39
U12026-1|AAA92670.1| 172|Homo sapiens Cap-G protein. 133 7e-31
U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein. 125 2e-28
U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog prot... 125 2e-28
BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog (D... 125 2e-28
AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog va... 125 2e-28
AL513122-7|CAI14416.1| 485|Homo sapiens gelsolin (amyloidosis, ... 93 9e-19
AK075198-1|BAC11465.1| 396|Homo sapiens protein ( Homo sapiens ... 81 4e-15
AK027778-1|BAB55361.1| 468|Homo sapiens protein ( Homo sapiens ... 81 4e-15
BC075797-1|AAH75797.1| 85|Homo sapiens Unknown (protein for MG... 73 1e-12
X07066-1|CAA30102.1| 69|Homo sapiens protein ( Human gene for ... 71 3e-12
D88154-1|BAA21668.1| 686|Homo sapiens villin-like protein protein. 62 1e-09
BC004300-1|AAH04300.1| 672|Homo sapiens VILL protein protein. 62 1e-09
BC000243-1|AAH00243.1| 686|Homo sapiens VILL protein protein. 62 1e-09
AL160060-2|CAH71300.1| 2214|Homo sapiens supervillin protein. 58 2e-08
AL158167-3|CAI15237.1| 2214|Homo sapiens supervillin protein. 58 2e-08
AF109135-1|AAD14682.1| 2214|Homo sapiens archvillin protein. 58 2e-08
AL160060-1|CAH71301.1| 1788|Homo sapiens supervillin protein. 58 2e-08
AL158167-2|CAI15236.1| 1788|Homo sapiens supervillin protein. 58 2e-08
AF051851-1|AAC64696.1| 1788|Homo sapiens supervillin protein. 58 2e-08
AF051850-1|AAC64695.1| 1788|Homo sapiens supervillin protein. 58 2e-08
BC017491-1|AAH17491.1| 285|Homo sapiens Similar to gelsolin (am... 56 1e-07
AK092426-1|BAC03887.1| 258|Homo sapiens protein ( Homo sapiens ... 36 0.14
BC117319-1|AAI17320.1| 257|Homo sapiens TPRXL protein protein. 33 0.73
AL513122-9|CAI14417.1| 207|Homo sapiens gelsolin (amyloidosis, ... 33 0.97
BC106877-1|AAI06878.1| 663|Homo sapiens chromosome 1 open readi... 32 2.2
AK001763-1|BAA91892.1| 663|Homo sapiens protein ( Homo sapiens ... 32 2.2
AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ ... 31 5.2
>AL513122-4|CAI14414.1| 228|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 228
Score = 219 bits (534), Expect = 1e-56
Identities = 105/217 (48%), Positives = 143/217 (65%), Gaps = 1/217 (0%)
Frame = +3
Query: 12 CTRPKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD- 188
C M H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++
Sbjct: 7 CFPNSMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNG 66
Query: 189 RLTWDIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAI 368
L +D+H+WLG+ SQDE+GAAAI TV LDD G AVQHREVQ +ES FL YF +
Sbjct: 67 NLQYDLHYWLGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYFKSGL 125
Query: 369 RYLKGGHASGFSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIF 548
+Y KGG ASGF HV NE +RLFQ+KG+R VR +V ++ES NNGDCFILD+ + I
Sbjct: 126 KYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIH 185
Query: 549 VFVGEKAKGVERMKALTVANQIKDQDHNGRADIEVGD 659
+ G + ER+KA V+ I+D + +GRA + V +
Sbjct: 186 QWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSE 222
>X04412-1|CAA28000.1| 782|Homo sapiens plasma gelsolin protein.
Length = 782
Score = 218 bits (532), Expect = 2e-56
Identities = 103/208 (49%), Positives = 141/208 (67%), Gaps = 1/208 (0%)
Frame = +3
Query: 39 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 215
H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++ L +D+H+W
Sbjct: 56 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 115
Query: 216 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHAS 395
LG+ SQDE+GAAAI TV LDD G AVQHREVQ +ES FL YF ++Y KGG AS
Sbjct: 116 LGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVAS 174
Query: 396 GFSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKG 575
GF HV NE +RLFQ+KG+R VR +V ++ES NNGDCFILD+ + I + G +
Sbjct: 175 GFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNR 234
Query: 576 VERMKALTVANQIKDQDHNGRADIEVGD 659
ER+KA V+ I+D + +GRA + V +
Sbjct: 235 YERLKATQVSKGIRDNERSGRARVHVSE 262
Score = 93.1 bits (221), Expect = 9e-19
Identities = 70/207 (33%), Positives = 99/207 (47%), Gaps = 4/207 (1%)
Frame = +3
Query: 78 EIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAAA 257
+IWRIE V V +G FY GDSYI+L R I+ W G++++QDE A+A
Sbjct: 448 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASA 507
Query: 258 ILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYLKGGHASGFSHVTINEGTE 431
ILT L DE+ G+ VQ R VQ E + F P I Y KGG S T T
Sbjct: 508 ILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIY-KGG-TSREGGQTAPAST- 563
Query: 432 KRLFQIKGKR--NVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVA 605
RLFQ++ R +V P +LN+ D F+L +++VG A E+ A +
Sbjct: 564 -RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELL 622
Query: 606 NQIKDQDHNGRADIEVGDSEAHDGSFE 686
++ Q ++V + DG +E
Sbjct: 623 RVLRAQ------PVQVAEGSEPDGFWE 643
Score = 42.3 bits (95), Expect = 0.002
Identities = 43/159 (27%), Positives = 71/159 (44%), Gaps = 8/159 (5%)
Frame = +3
Query: 201 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLK 380
+IH W GS +++ E A ++ + D + G A H + E + L+ P L
Sbjct: 223 NIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPK-PALP 281
Query: 381 GGHASGFSHVTINEGTEKRLFQIK---GKRNVRVKQVKPTFE--SLNNGDCFILD--VDH 539
G N K L+++ G +V + + F +L + DCFILD D
Sbjct: 282 AGTEDTAKEDAANRKLAK-LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDG 340
Query: 540 QIFVFVGEKAKGVERMKAL-TVANQIKDQDHNGRADIEV 653
+IFV+ G++A ER AL T ++ I D+ + + V
Sbjct: 341 KIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSV 379
Score = 33.1 bits (72), Expect = 0.97
Identities = 17/48 (35%), Positives = 27/48 (56%)
Frame = +3
Query: 495 ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVANQIKDQDHNGR 638
E L D +LD Q+FV+VG+ ++ E+ +ALT A + + D R
Sbjct: 691 EDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANR 738
>BC026033-1|AAH26033.1| 782|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 782
Score = 218 bits (532), Expect = 2e-56
Identities = 103/208 (49%), Positives = 141/208 (67%), Gaps = 1/208 (0%)
Frame = +3
Query: 39 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 215
H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++ L +D+H+W
Sbjct: 56 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 115
Query: 216 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHAS 395
LG+ SQDE+GAAAI TV LDD G AVQHREVQ +ES FL YF ++Y KGG AS
Sbjct: 116 LGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVAS 174
Query: 396 GFSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKG 575
GF HV NE +RLFQ+KG+R VR +V ++ES NNGDCFILD+ + I + G +
Sbjct: 175 GFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNR 234
Query: 576 VERMKALTVANQIKDQDHNGRADIEVGD 659
ER+KA V+ I+D + +GRA + V +
Sbjct: 235 YERLKATQVSKGIRDNERSGRARVHVSE 262
Score = 93.1 bits (221), Expect = 9e-19
Identities = 70/207 (33%), Positives = 99/207 (47%), Gaps = 4/207 (1%)
Frame = +3
Query: 78 EIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAAA 257
+IWRIE V V +G FY GDSYI+L R I+ W G++++QDE A+A
Sbjct: 448 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASA 507
Query: 258 ILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYLKGGHASGFSHVTINEGTE 431
ILT L DE+ G+ VQ R VQ E + F P I Y KGG S T T
Sbjct: 508 ILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIY-KGG-TSREGGQTAPAST- 563
Query: 432 KRLFQIKGKR--NVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVA 605
RLFQ++ R +V P +LN+ D F+L +++VG A E+ A +
Sbjct: 564 -RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELL 622
Query: 606 NQIKDQDHNGRADIEVGDSEAHDGSFE 686
++ Q ++V + DG +E
Sbjct: 623 RVLRAQ------PVQVAEGSEPDGFWE 643
Score = 42.3 bits (95), Expect = 0.002
Identities = 43/159 (27%), Positives = 71/159 (44%), Gaps = 8/159 (5%)
Frame = +3
Query: 201 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLK 380
+IH W GS +++ E A ++ + D + G A H + E + L+ P L
Sbjct: 223 NIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPK-PALP 281
Query: 381 GGHASGFSHVTINEGTEKRLFQIK---GKRNVRVKQVKPTFE--SLNNGDCFILD--VDH 539
G N K L+++ G +V + + F +L + DCFILD D
Sbjct: 282 AGTEDTAKEDAANRKLAK-LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDG 340
Query: 540 QIFVFVGEKAKGVERMKAL-TVANQIKDQDHNGRADIEV 653
+IFV+ G++A ER AL T ++ I D+ + + V
Sbjct: 341 KIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSV 379
Score = 33.1 bits (72), Expect = 0.97
Identities = 17/48 (35%), Positives = 27/48 (56%)
Frame = +3
Query: 495 ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVANQIKDQDHNGR 638
E L D +LD Q+FV+VG+ ++ E+ +ALT A + + D R
Sbjct: 691 EDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANR 738
>AL513122-6|CAM20459.1| 731|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 731
Score = 218 bits (532), Expect = 2e-56
Identities = 103/208 (49%), Positives = 141/208 (67%), Gaps = 1/208 (0%)
Frame = +3
Query: 39 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 215
H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++ L +D+H+W
Sbjct: 5 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 64
Query: 216 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHAS 395
LG+ SQDE+GAAAI TV LDD G AVQHREVQ +ES FL YF ++Y KGG AS
Sbjct: 65 LGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVAS 123
Query: 396 GFSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKG 575
GF HV NE +RLFQ+KG+R VR +V ++ES NNGDCFILD+ + I + G +
Sbjct: 124 GFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNR 183
Query: 576 VERMKALTVANQIKDQDHNGRADIEVGD 659
ER+KA V+ I+D + +GRA + V +
Sbjct: 184 YERLKATQVSKGIRDNERSGRARVHVSE 211
Score = 93.1 bits (221), Expect = 9e-19
Identities = 70/207 (33%), Positives = 99/207 (47%), Gaps = 4/207 (1%)
Frame = +3
Query: 78 EIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAAA 257
+IWRIE V V +G FY GDSYI+L R I+ W G++++QDE A+A
Sbjct: 397 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASA 456
Query: 258 ILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYLKGGHASGFSHVTINEGTE 431
ILT L DE+ G+ VQ R VQ E + F P I Y KGG S T T
Sbjct: 457 ILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIY-KGG-TSREGGQTAPAST- 512
Query: 432 KRLFQIKGKR--NVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVA 605
RLFQ++ R +V P +LN+ D F+L +++VG A E+ A +
Sbjct: 513 -RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELL 571
Query: 606 NQIKDQDHNGRADIEVGDSEAHDGSFE 686
++ Q ++V + DG +E
Sbjct: 572 RVLRAQ------PVQVAEGSEPDGFWE 592
Score = 42.3 bits (95), Expect = 0.002
Identities = 43/159 (27%), Positives = 71/159 (44%), Gaps = 8/159 (5%)
Frame = +3
Query: 201 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLK 380
+IH W GS +++ E A ++ + D + G A H + E + L+ P L
Sbjct: 172 NIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPK-PALP 230
Query: 381 GGHASGFSHVTINEGTEKRLFQIK---GKRNVRVKQVKPTFE--SLNNGDCFILD--VDH 539
G N K L+++ G +V + + F +L + DCFILD D
Sbjct: 231 AGTEDTAKEDAANRKLAK-LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDG 289
Query: 540 QIFVFVGEKAKGVERMKAL-TVANQIKDQDHNGRADIEV 653
+IFV+ G++A ER AL T ++ I D+ + + V
Sbjct: 290 KIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSV 328
Score = 33.1 bits (72), Expect = 0.97
Identities = 17/48 (35%), Positives = 27/48 (56%)
Frame = +3
Query: 495 ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVANQIKDQDHNGR 638
E L D +LD Q+FV+VG+ ++ E+ +ALT A + + D R
Sbjct: 640 EDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANR 687
>AL513122-5|CAI14415.1| 260|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 260
Score = 218 bits (532), Expect = 2e-56
Identities = 103/208 (49%), Positives = 141/208 (67%), Gaps = 1/208 (0%)
Frame = +3
Query: 39 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 215
H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++ L +D+H+W
Sbjct: 5 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 64
Query: 216 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHAS 395
LG+ SQDE+GAAAI TV LDD G AVQHREVQ +ES FL YF ++Y KGG AS
Sbjct: 65 LGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVAS 123
Query: 396 GFSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKG 575
GF HV NE +RLFQ+KG+R VR +V ++ES NNGDCFILD+ + I + G +
Sbjct: 124 GFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNR 183
Query: 576 VERMKALTVANQIKDQDHNGRADIEVGD 659
ER+KA V+ I+D + +GRA + V +
Sbjct: 184 YERLKATQVSKGIRDNERSGRARVHVSE 211
>AL513122-3|CAI14413.1| 782|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 782
Score = 218 bits (532), Expect = 2e-56
Identities = 103/208 (49%), Positives = 141/208 (67%), Gaps = 1/208 (0%)
Frame = +3
Query: 39 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 215
H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++ L +D+H+W
Sbjct: 56 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 115
Query: 216 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHAS 395
LG+ SQDE+GAAAI TV LDD G AVQHREVQ +ES FL YF ++Y KGG AS
Sbjct: 116 LGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVAS 174
Query: 396 GFSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKG 575
GF HV NE +RLFQ+KG+R VR +V ++ES NNGDCFILD+ + I + G +
Sbjct: 175 GFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNR 234
Query: 576 VERMKALTVANQIKDQDHNGRADIEVGD 659
ER+KA V+ I+D + +GRA + V +
Sbjct: 235 YERLKATQVSKGIRDNERSGRARVHVSE 262
Score = 93.1 bits (221), Expect = 9e-19
Identities = 70/207 (33%), Positives = 99/207 (47%), Gaps = 4/207 (1%)
Frame = +3
Query: 78 EIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAAA 257
+IWRIE V V +G FY GDSYI+L R I+ W G++++QDE A+A
Sbjct: 448 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASA 507
Query: 258 ILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYLKGGHASGFSHVTINEGTE 431
ILT L DE+ G+ VQ R VQ E + F P I Y KGG S T T
Sbjct: 508 ILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIY-KGG-TSREGGQTAPAST- 563
Query: 432 KRLFQIKGKR--NVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVA 605
RLFQ++ R +V P +LN+ D F+L +++VG A E+ A +
Sbjct: 564 -RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELL 622
Query: 606 NQIKDQDHNGRADIEVGDSEAHDGSFE 686
++ Q ++V + DG +E
Sbjct: 623 RVLRAQ------PVQVAEGSEPDGFWE 643
Score = 42.3 bits (95), Expect = 0.002
Identities = 43/159 (27%), Positives = 71/159 (44%), Gaps = 8/159 (5%)
Frame = +3
Query: 201 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLK 380
+IH W GS +++ E A ++ + D + G A H + E + L+ P L
Sbjct: 223 NIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPK-PALP 281
Query: 381 GGHASGFSHVTINEGTEKRLFQIK---GKRNVRVKQVKPTFE--SLNNGDCFILD--VDH 539
G N K L+++ G +V + + F +L + DCFILD D
Sbjct: 282 AGTEDTAKEDAANRKLAK-LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDG 340
Query: 540 QIFVFVGEKAKGVERMKAL-TVANQIKDQDHNGRADIEV 653
+IFV+ G++A ER AL T ++ I D+ + + V
Sbjct: 341 KIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSV 379
Score = 33.1 bits (72), Expect = 0.97
Identities = 17/48 (35%), Positives = 27/48 (56%)
Frame = +3
Query: 495 ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVANQIKDQDHNGR 638
E L D +LD Q+FV+VG+ ++ E+ +ALT A + + D R
Sbjct: 691 EDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANR 738
>AF276507-1|AAK60494.1| 715|Homo sapiens scinderin protein.
Length = 715
Score = 195 bits (475), Expect = 1e-49
Identities = 93/205 (45%), Positives = 132/205 (64%)
Frame = +3
Query: 39 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 218
H+ FA AG++ GL++WRIE E V VP++ G FY GD+Y+VL+T T+ +HFWL
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWL 66
Query: 219 GSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASG 398
G SQDE+ AAAI TV +DD G VQ+RE+Q YES +F+ YF ++Y GG ASG
Sbjct: 67 GKECSQDESTAAAIFTVQMDD-YLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125
Query: 399 FSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGV 578
+HV N+ T KRL +KG+R VR +V +++S N GDCFI+D+ +I+ + G
Sbjct: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185
Query: 579 ERMKALTVANQIKDQDHNGRADIEV 653
ER+KA VA I+ + GR+++ V
Sbjct: 186 ERLKANQVATGIRYNERKGRSELIV 210
Score = 81.4 bits (192), Expect = 3e-15
Identities = 68/206 (33%), Positives = 97/206 (47%), Gaps = 7/206 (3%)
Frame = +3
Query: 21 PKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTW 200
P+M H D K +EIWR+EN + V + +G FY GD YI+L T + ++
Sbjct: 382 PQMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI-- 436
Query: 201 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRY 374
I+ W G+ ++DE +A LTV L D G AVQ R Q E L F P I Y
Sbjct: 437 -IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQDKEPVHLLSLFKDKPLIIY 494
Query: 375 LKGGHASGFSHVTINEGTEKRLFQIKGKRNV----RVKQVKPTFESLNNGDCFILDVDHQ 542
G G RLFQ+ +RN+ R+ +V SLN+ D F+L +
Sbjct: 495 KNGTSKKGGQ----APAPPTRLFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLSQN 548
Query: 543 I-FVFVGEKAKGVERMKALTVANQIK 617
+++VG+ A E A VA+ +K
Sbjct: 549 SGYIWVGKGASQEEEKGAEYVASVLK 574
Score = 35.9 bits (79), Expect = 0.14
Identities = 17/50 (34%), Positives = 28/50 (56%)
Frame = +3
Query: 489 TFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVANQIKDQDHNGR 638
T + L D +LD QIF+++G+ A VE+ ++L A + D +GR
Sbjct: 636 TQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGR 685
>AC005281-1|AAD15423.1| 527|Homo sapiens WUGSC:H_DJ0722F20.1
protein.
Length = 527
Score = 195 bits (475), Expect = 1e-49
Identities = 93/205 (45%), Positives = 132/205 (64%)
Frame = +3
Query: 39 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 218
H+ FA AG++ GL++WRIE E V VP++ G FY GD+Y+VL+T T+ +HFWL
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWL 66
Query: 219 GSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASG 398
G SQDE+ AAAI TV +DD G VQ+RE+Q YES +F+ YF ++Y GG ASG
Sbjct: 67 GKECSQDESTAAAIFTVQMDD-YLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125
Query: 399 FSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGV 578
+HV N+ T KRL +KG+R VR +V +++S N GDCFI+D+ +I+ + G
Sbjct: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185
Query: 579 ERMKALTVANQIKDQDHNGRADIEV 653
ER+KA VA I+ + GR+++ V
Sbjct: 186 ERLKANQVATGIRYNERKGRSELIV 210
Score = 66.1 bits (154), Expect = 1e-10
Identities = 46/128 (35%), Positives = 61/128 (47%), Gaps = 2/128 (1%)
Frame = +3
Query: 21 PKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTW 200
P+M H D K +EIWR+EN + V + +G FY GD YI+L T + ++
Sbjct: 382 PQMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI-- 436
Query: 201 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRY 374
I+ W G+ ++DE +A LTV L D G AVQ R Q E L F P I Y
Sbjct: 437 -IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIY 494
Query: 375 LKGGHASG 398
G G
Sbjct: 495 KNGTSKKG 502
>AB067492-1|BAB67798.1| 626|Homo sapiens KIAA1905 protein protein.
Length = 626
Score = 195 bits (475), Expect = 1e-49
Identities = 93/205 (45%), Positives = 132/205 (64%)
Frame = +3
Query: 39 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 218
H+ FA AG++ GL++WRIE E V VP++ G FY GD+Y+VL+T T+ +HFWL
Sbjct: 53 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWL 112
Query: 219 GSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASG 398
G SQDE+ AAAI TV +DD G VQ+RE+Q YES +F+ YF ++Y GG ASG
Sbjct: 113 GKECSQDESTAAAIFTVQMDD-YLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 171
Query: 399 FSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGV 578
+HV N+ T KRL +KG+R VR +V +++S N GDCFI+D+ +I+ + G
Sbjct: 172 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 231
Query: 579 ERMKALTVANQIKDQDHNGRADIEV 653
ER+KA VA I+ + GR+++ V
Sbjct: 232 ERLKANQVATGIRYNERKGRSELIV 256
Score = 66.1 bits (154), Expect = 1e-10
Identities = 46/128 (35%), Positives = 61/128 (47%), Gaps = 2/128 (1%)
Frame = +3
Query: 21 PKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTW 200
P+M H D K +EIWR+EN + V + +G FY GD YI+L T + ++
Sbjct: 428 PQMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI-- 482
Query: 201 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRY 374
I+ W G+ ++DE +A LTV L D G AVQ R Q E L F P I Y
Sbjct: 483 -IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIY 540
Query: 375 LKGGHASG 398
G G
Sbjct: 541 KNGTSKKG 548
>BC021090-1|AAH21090.1| 715|Homo sapiens SCIN protein protein.
Length = 715
Score = 194 bits (474), Expect = 2e-49
Identities = 93/205 (45%), Positives = 132/205 (64%)
Frame = +3
Query: 39 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 218
H+ FA AG++ GL++WRIE E V VP++ G FY GD+Y+VL+T T+ +HFWL
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYRLHFWL 66
Query: 219 GSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASG 398
G SQDE+ AAAI TV +DD G VQ+RE+Q YES +F+ YF ++Y GG ASG
Sbjct: 67 GKECSQDESTAAAIFTVQMDD-YLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125
Query: 399 FSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGV 578
+HV N+ T KRL +KG+R VR +V +++S N GDCFI+D+ +I+ + G
Sbjct: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185
Query: 579 ERMKALTVANQIKDQDHNGRADIEV 653
ER+KA VA I+ + GR+++ V
Sbjct: 186 ERLKANQVATGIRYNERKGRSELIV 210
Score = 81.0 bits (191), Expect = 4e-15
Identities = 68/206 (33%), Positives = 98/206 (47%), Gaps = 7/206 (3%)
Frame = +3
Query: 21 PKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTW 200
P+M H D K +EIWR+EN + V + +G FY GD YI+L T + ++
Sbjct: 382 PQMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI-- 436
Query: 201 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRY 374
I+ W G+ ++DE +A LTV L D G AVQ R Q E L F P I Y
Sbjct: 437 -IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIY 494
Query: 375 LKGGHASGFSHVTINEGTEKRLFQIKGKRNV----RVKQVKPTFESLNNGDCFILDV-DH 539
G G RLFQ+ +RN+ R+ +V SLN+ D F+L + +
Sbjct: 495 KNGTSKKGGQ----APAPPTRLFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLPQN 548
Query: 540 QIFVFVGEKAKGVERMKALTVANQIK 617
+++VG+ A E A VA+ +K
Sbjct: 549 SGYIWVGKGASQEEEKGAEYVASVLK 574
Score = 35.9 bits (79), Expect = 0.14
Identities = 17/50 (34%), Positives = 28/50 (56%)
Frame = +3
Query: 489 TFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVANQIKDQDHNGR 638
T + L D +LD QIF+++G+ A VE+ ++L A + D +GR
Sbjct: 636 TQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGR 685
>AK075123-1|BAC11416.1| 715|Homo sapiens protein ( Homo sapiens
cDNA FLJ90642 fis, clone PLACE1004078, highly similar to
Bovine mRNA for adseverin. ).
Length = 715
Score = 194 bits (472), Expect = 3e-49
Identities = 92/205 (44%), Positives = 132/205 (64%)
Frame = +3
Query: 39 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 218
H+ FA AG++ GL++WRIE E V VP++ G FY GD+Y++L+T T+ +HFWL
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLMLHTAKTSRGFTYHLHFWL 66
Query: 219 GSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASG 398
G SQDE+ AAAI TV +DD G VQ+RE+Q YES +F+ YF ++Y GG ASG
Sbjct: 67 GKECSQDESTAAAIFTVQMDD-YLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125
Query: 399 FSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGV 578
+HV N+ T KRL +KG+R VR +V +++S N GDCFI+D+ +I+ + G
Sbjct: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185
Query: 579 ERMKALTVANQIKDQDHNGRADIEV 653
ER+KA VA I+ + GR+++ V
Sbjct: 186 ERLKANQVATGIRYNERKGRSELIV 210
Score = 81.0 bits (191), Expect = 4e-15
Identities = 68/206 (33%), Positives = 98/206 (47%), Gaps = 7/206 (3%)
Frame = +3
Query: 21 PKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTW 200
P+M H D K +EIWR+EN + V + +G FY GD YI+L T + ++
Sbjct: 382 PQMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI-- 436
Query: 201 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRY 374
I+ W G+ ++DE +A LTV L D G AVQ R Q E L F P I Y
Sbjct: 437 -IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIY 494
Query: 375 LKGGHASGFSHVTINEGTEKRLFQIKGKRNV----RVKQVKPTFESLNNGDCFILDV-DH 539
G G RLFQ+ +RN+ R+ +V SLN+ D F+L + +
Sbjct: 495 KNGTSKKGGQ----APAPPTRLFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLPQN 548
Query: 540 QIFVFVGEKAKGVERMKALTVANQIK 617
+++VG+ A E A VA+ +K
Sbjct: 549 SGYIWVGKGASQEEEKGAEYVASVLK 574
Score = 35.9 bits (79), Expect = 0.14
Identities = 17/50 (34%), Positives = 28/50 (56%)
Frame = +3
Query: 489 TFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVANQIKDQDHNGR 638
T + L D +LD QIF+++G+ A VE+ ++L A + D +GR
Sbjct: 636 TQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGR 685
>AF041449-1|AAC25051.1| 819|Homo sapiens advillin protein.
Length = 819
Score = 190 bits (464), Expect = 3e-48
Identities = 97/210 (46%), Positives = 127/210 (60%), Gaps = 2/210 (0%)
Frame = +3
Query: 45 AFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGS 224
AF PG+ +WRIE E VP + G FY GD Y++L+T L+ DIHFW+G
Sbjct: 6 AFRAVDNDPGIIVWRIEKMELALVPVSAHGNFYEGDCYVILSTRRVASLLSQDIHFWIGK 65
Query: 225 RTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFS 404
+SQDE AAI T LDD GS VQHREVQY+ES F YF I Y +GG ASG
Sbjct: 66 DSSQDEQSCAAIYTTQLDD-YLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMK 124
Query: 405 HVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVER 584
HV N KRL +KGKRN+R +V+ +++S N GD F+LD+ I + G ++ ER
Sbjct: 125 HVETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGER 184
Query: 585 MKALTVANQIKDQDHNGRADIEV--GDSEA 668
+KA+ +A I+D++ GRA+I V GD EA
Sbjct: 185 LKAMLLAKDIRDRERGGRAEIGVIEGDKEA 214
Score = 97.1 bits (231), Expect = 5e-20
Identities = 67/212 (31%), Positives = 100/212 (47%), Gaps = 2/212 (0%)
Frame = +3
Query: 15 TRPKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRL 194
T+P++ + D K +E+WRIEN E V V +G FY GD Y+VL T +
Sbjct: 379 TKPEVAAQERMVDDGNGK--VEVWRIENLELVPVEYQWYGFFYGGDCYLVLYTYEVNGKP 436
Query: 195 TWDIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRY 374
++ W SQDE A+A V + D QF G+AVQ R E + F+ F +
Sbjct: 437 HHILYIWQDRHASQDELAASAYQAVEV-DRQFDGAAVQVRVRMGTEPRHFMAIFKGKLVI 495
Query: 375 LKGGHASGFSHVTINEGTEKRLFQIKG--KRNVRVKQVKPTFESLNNGDCFILDVDHQIF 548
+GG + RLFQI G K N + +V SLN+ D F+L + +
Sbjct: 496 FEGGTS---RKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAEHY 552
Query: 549 VFVGEKAKGVERMKALTVANQIKDQDHNGRAD 644
++ G+ + G ER A +A+ + D N A+
Sbjct: 553 LWYGKGSSGDERAMAKELASLLCDGSENTVAE 584
Score = 36.3 bits (80), Expect = 0.10
Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Frame = +3
Query: 429 EKRLFQIKGKRN--VRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTV 602
+ RLF+ K V + T + LN D +LD Q+F+++G +A E+ AL
Sbjct: 615 QSRLFECSNKTGQFVVTEITDFTQDDLNPTDVMLLDTWDQVFLWIGAEANATEKESALAT 674
Query: 603 ANQIKDQDHNGR 638
A Q +GR
Sbjct: 675 AQQYLHTHPSGR 686
Score = 30.7 bits (66), Expect = 5.2
Identities = 19/64 (29%), Positives = 34/64 (53%), Gaps = 2/64 (3%)
Frame = +3
Query: 501 LNNGDCFILDVD-HQIFVFVGEKAKGVERMKALTVA-NQIKDQDHNGRADIEVGDSEAHD 674
LN+ DC+ILD +I+V+ G+ A E+ A++ A IK + + ++E + A
Sbjct: 277 LNHDDCYILDQSGTKIYVWKGKGATKAEKQAAMSKALGFIKMKSYPSSTNVETVNDGAES 336
Query: 675 GSFE 686
F+
Sbjct: 337 AMFK 340
>X12901-1|CAA31386.1| 827|Homo sapiens protein ( Human mRNA for
villin. ).
Length = 827
Score = 179 bits (436), Expect = 8e-45
Identities = 89/199 (44%), Positives = 124/199 (62%)
Frame = +3
Query: 69 PGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAG 248
PGL+IWRIE + V VP + FG F+ GD YI+L L++DIH+W+G +S DE G
Sbjct: 17 PGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASSLSYDIHYWIGQDSSLDEQG 76
Query: 249 AAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFSHVTINEGT 428
AAAI T +DD +G AVQHREVQ ES+ F YF + KGG ASG HV N
Sbjct: 77 AAAIYTTQMDDF-LKGRAVQHREVQGNESEAFRGYFKQGLVIRKGGVASGMKHVETNSYD 135
Query: 429 EKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVAN 608
+RL +KGKRNV +V+ +++S N GD F+LD+ I + G ++ +ER++ +T+A
Sbjct: 136 VQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAK 195
Query: 609 QIKDQDHNGRADIEVGDSE 665
+I+DQ+ GR + V D E
Sbjct: 196 EIRDQERGGRTYVGVVDGE 214
Score = 87.4 bits (207), Expect = 4e-17
Identities = 57/182 (31%), Positives = 89/182 (48%), Gaps = 2/182 (1%)
Frame = +3
Query: 75 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAA 254
+++WRIEN E V V G FY GD Y++L T ++ + ++ W GS+ SQDE A+
Sbjct: 400 VQVWRIENLELVPVDSKWLGHFYGGDCYLLLYTYLIGEKQHYLLYVWQGSQASQDEITAS 459
Query: 255 AILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFSHVTINEGTEK 434
A V L D+++ G VQ R E + F + +GG + + + G
Sbjct: 460 AYQAVIL-DQKYNGEPVQIRVPMGKEPPHLMSIFKGRMVVYQGGTSRTNN---LETGPST 515
Query: 435 RLFQIK--GKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVAN 608
RLFQ++ G N + +V LN+ D F+L +++ G+ G ER A VA+
Sbjct: 516 RLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKTQSCCYLWCGKGCSGDEREMAKMVAD 575
Query: 609 QI 614
I
Sbjct: 576 TI 577
Score = 36.3 bits (80), Expect = 0.10
Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Frame = +3
Query: 435 RLFQIKGKRNVRVKQVKPTF--ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVAN 608
RLF+ K + P F + L D F+LDV Q+F ++G+ A E+ A T A
Sbjct: 620 RLFECSNKTGRFLATEIPDFNQDDLEEDDVFLLDVWDQVFFWIGKHANEEEKKAAATTAQ 679
Query: 609 QIKDQDHNGR 638
+ +GR
Sbjct: 680 EYLKTHPSGR 689
>BC017303-1|AAH17303.1| 421|Homo sapiens VIL1 protein protein.
Length = 421
Score = 179 bits (436), Expect = 8e-45
Identities = 89/199 (44%), Positives = 124/199 (62%)
Frame = +3
Query: 69 PGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAG 248
PGL+IWRIE + V VP + FG F+ GD YI+L L++DIH+W+G +S DE G
Sbjct: 17 PGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASSLSYDIHYWIGQDSSLDEQG 76
Query: 249 AAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFSHVTINEGT 428
AAAI T +DD +G AVQHREVQ ES+ F YF + KGG ASG HV N
Sbjct: 77 AAAIYTTQMDDF-LKGRAVQHREVQGNESEAFRGYFKQGLVIRKGGVASGMKHVETNSYD 135
Query: 429 EKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVAN 608
+RL +KGKRNV +V+ +++S N GD F+LD+ I + G ++ +ER++ +T+A
Sbjct: 136 VQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAK 195
Query: 609 QIKDQDHNGRADIEVGDSE 665
+I+DQ+ GR + V D E
Sbjct: 196 EIRDQERGGRTYVGVVDGE 214
>AK223398-1|BAD97118.1| 827|Homo sapiens villin 1 variant protein.
Length = 827
Score = 179 bits (436), Expect = 8e-45
Identities = 89/199 (44%), Positives = 124/199 (62%)
Frame = +3
Query: 69 PGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAG 248
PGL+IWRIE + V VP + FG F+ GD YI+L L++DIH+W+G +S DE G
Sbjct: 17 PGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASSLSYDIHYWIGQDSSLDEQG 76
Query: 249 AAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFSHVTINEGT 428
AAAI T +DD +G AVQHREVQ ES+ F YF + KGG ASG HV N
Sbjct: 77 AAAIYTTQMDDF-LKGRAVQHREVQGNESEAFRGYFKQGLVIRKGGVASGMKHVETNSYD 135
Query: 429 EKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVAN 608
+RL +KGKRNV +V+ +++S N GD F+LD+ I + G ++ +ER++ +T+A
Sbjct: 136 VQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAK 195
Query: 609 QIKDQDHNGRADIEVGDSE 665
+I+DQ+ GR + V D E
Sbjct: 196 EIRDQERGGRTYVGVVDGE 214
Score = 87.4 bits (207), Expect = 4e-17
Identities = 57/182 (31%), Positives = 89/182 (48%), Gaps = 2/182 (1%)
Frame = +3
Query: 75 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAA 254
+++WRIEN E V V G FY GD Y++L T ++ + ++ W GS+ SQDE A+
Sbjct: 400 VQVWRIENLELVPVDSKWLGHFYGGDCYLLLYTYLIGEKQHYLLYVWQGSQASQDEITAS 459
Query: 255 AILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFSHVTINEGTEK 434
A V L D+++ G VQ R E + F + +GG + + + G
Sbjct: 460 AYQAVIL-DQKYNGEPVQIRVPMGKEPPHLMSIFKGRMVVYQGGTSRTNN---LETGPST 515
Query: 435 RLFQIK--GKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVAN 608
RLFQ++ G N + +V LN+ D F+L +++ G+ G ER A VA+
Sbjct: 516 RLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKTQSCCYLWCGKGCSGDEREMAKMVAD 575
Query: 609 QI 614
I
Sbjct: 576 TI 577
Score = 36.3 bits (80), Expect = 0.10
Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Frame = +3
Query: 435 RLFQIKGKRNVRVKQVKPTF--ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVAN 608
RLF+ K + P F + L D F+LDV Q+F ++G+ A E+ A T A
Sbjct: 620 RLFECSNKTGRFLATEIPDFNQDDLEEDDVFLLDVWDQVFFWIGKHANEEEKKAAATTAQ 679
Query: 609 QIKDQDHNGR 638
+ +GR
Sbjct: 680 EYLKTHPSGR 689
>BC111730-1|AAI11731.1| 812|Homo sapiens AVIL protein protein.
Length = 812
Score = 177 bits (430), Expect = 4e-44
Identities = 93/208 (44%), Positives = 123/208 (59%), Gaps = 2/208 (0%)
Frame = +3
Query: 51 ADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRT 230
+ G +IW E E VP + G FY GD Y++L+T L+ DIHFW+G +
Sbjct: 2 SSTGHPGSYKIWG-EKMELALVPVSAHGNFYEGDCYVILSTRRVASLLSQDIHFWIGKDS 60
Query: 231 SQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFSHV 410
SQDE AAI T LDD GS VQHREVQY+ES F YF I Y +GG ASG HV
Sbjct: 61 SQDEQSCAAIYTTQLDD-YLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMKHV 119
Query: 411 TINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMK 590
N KRL +KGKRN+R +V+ +++S N GD F+LD+ I + G ++ ER+K
Sbjct: 120 ETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERLK 179
Query: 591 ALTVANQIKDQDHNGRADIEV--GDSEA 668
A+ +A I+D++ GRA+I V GD EA
Sbjct: 180 AMLLAKDIRDRERGGRAEIGVIEGDKEA 207
Score = 99 bits (238), Expect = 7e-21
Identities = 68/212 (32%), Positives = 101/212 (47%), Gaps = 2/212 (0%)
Frame = +3
Query: 15 TRPKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRL 194
T+P++ + D K +E+WRIEN E V V +G FY GD Y+VL T +
Sbjct: 372 TKPEVAAQERMVDDGNGK--VEVWRIENLELVPVEYQWYGFFYGGDCYLVLYTYEVNGKP 429
Query: 195 TWDIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRY 374
++ W G SQDE A+A V + D QF G+AVQ R E + F+ F +
Sbjct: 430 HHILYIWQGRHASQDELAASAYQAVEV-DRQFDGAAVQVRVRMGTEPRHFMAIFKGKLVI 488
Query: 375 LKGGHASGFSHVTINEGTEKRLFQIKG--KRNVRVKQVKPTFESLNNGDCFILDVDHQIF 548
+GG + RLFQI G K N + +V SLN+ D F+L + +
Sbjct: 489 FEGGTS---RKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAEHY 545
Query: 549 VFVGEKAKGVERMKALTVANQIKDQDHNGRAD 644
++ G+ + G ER A +A+ + D N A+
Sbjct: 546 LWYGKGSSGDERAMAKELASLLCDGSENTVAE 577
Score = 36.3 bits (80), Expect = 0.10
Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Frame = +3
Query: 429 EKRLFQIKGKRN--VRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTV 602
+ RLF+ K V + T + LN D +LD Q+F+++G +A E+ AL
Sbjct: 608 QSRLFECSNKTGQFVVTEITDFTQDDLNPTDVMLLDTWDQVFLWIGAEANATEKESALAT 667
Query: 603 ANQIKDQDHNGR 638
A Q +GR
Sbjct: 668 AQQYLHTHPSGR 679
Score = 30.7 bits (66), Expect = 5.2
Identities = 19/64 (29%), Positives = 34/64 (53%), Gaps = 2/64 (3%)
Frame = +3
Query: 501 LNNGDCFILDVD-HQIFVFVGEKAKGVERMKALTVA-NQIKDQDHNGRADIEVGDSEAHD 674
LN+ DC+ILD +I+V+ G+ A E+ A++ A IK + + ++E + A
Sbjct: 270 LNHDDCYILDQSGTKIYVWKGKGATKAEKQAAMSKALGFIKMKSYPSSTNVETVNDGAES 329
Query: 675 GSFE 686
F+
Sbjct: 330 AMFK 333
>M94345-1|AAA59570.1| 348|Homo sapiens macrophage capping protein
protein.
Length = 348
Score = 160 bits (389), Expect = 4e-39
Identities = 80/210 (38%), Positives = 126/210 (60%), Gaps = 1/210 (0%)
Frame = +3
Query: 27 MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 206
+P+ F + + PGL +WR+E +PV V + G+F+SGDSY+VL+ ++ +
Sbjct: 5 IPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEE---VSHL 61
Query: 207 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 386
H W+G ++S+DE GA A+L V+L+ + VQHREVQ ES F+ YF ++Y +GG
Sbjct: 62 HLWIGQQSSRDEQGACAVLAVHLNTLLGE-RPVQHREVQGNESDLFMSYFPRGLKYQEGG 120
Query: 387 HASGFSHVTINEGTE-KRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGE 563
S F + K+L+Q+KGK+N+R + ++S N GDCFILD+ IF + G
Sbjct: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGG 180
Query: 564 KAKGVERMKALTVANQIKDQDHNGRADIEV 653
K+ +ER KA +A I+D + G+A +E+
Sbjct: 181 KSNILERNKARDLALAIRDSERQGKAQVEI 210
>BC014549-1|AAH14549.1| 348|Homo sapiens capping protein (actin
filament), gelsolin-like protein.
Length = 348
Score = 160 bits (389), Expect = 4e-39
Identities = 80/210 (38%), Positives = 126/210 (60%), Gaps = 1/210 (0%)
Frame = +3
Query: 27 MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 206
+P+ F + + PGL +WR+E +PV V + G+F+SGDSY+VL+ ++ +
Sbjct: 5 IPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEE---VSHL 61
Query: 207 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 386
H W+G ++S+DE GA A+L V+L+ + VQHREVQ ES F+ YF ++Y +GG
Sbjct: 62 HLWIGQQSSRDEQGACAVLAVHLNTLLGE-RPVQHREVQGNESDLFMSYFPRGLKYQEGG 120
Query: 387 HASGFSHVTINEGTE-KRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGE 563
S F + K+L+Q+KGK+N+R + ++S N GDCFILD+ IF + G
Sbjct: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGG 180
Query: 564 KAKGVERMKALTVANQIKDQDHNGRADIEV 653
K+ +ER KA +A I+D + G+A +E+
Sbjct: 181 KSNILERNKARDLALAIRDSERQGKAQVEI 210
>BC000728-1|AAH00728.1| 348|Homo sapiens capping protein (actin
filament), gelsolin-like protein.
Length = 348
Score = 160 bits (389), Expect = 4e-39
Identities = 80/210 (38%), Positives = 126/210 (60%), Gaps = 1/210 (0%)
Frame = +3
Query: 27 MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 206
+P+ F + + PGL +WR+E +PV V + G+F+SGDSY+VL+ ++ +
Sbjct: 5 IPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEE---VSHL 61
Query: 207 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 386
H W+G ++S+DE GA A+L V+L+ + VQHREVQ ES F+ YF ++Y +GG
Sbjct: 62 HLWIGQQSSRDEQGACAVLAVHLNTLLGE-RPVQHREVQGNESDLFMSYFPRGLKYQEGG 120
Query: 387 HASGFSHVTINEGTE-KRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGE 563
S F + K+L+Q+KGK+N+R + ++S N GDCFILD+ IF + G
Sbjct: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGG 180
Query: 564 KAKGVERMKALTVANQIKDQDHNGRADIEV 653
K+ +ER KA +A I+D + G+A +E+
Sbjct: 181 KSNILERNKARDLALAIRDSERQGKAQVEI 210
>AC062037-3|AAY24128.1| 348|Homo sapiens unknown protein.
Length = 348
Score = 160 bits (389), Expect = 4e-39
Identities = 80/210 (38%), Positives = 126/210 (60%), Gaps = 1/210 (0%)
Frame = +3
Query: 27 MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 206
+P+ F + + PGL +WR+E +PV V + G+F+SGDSY+VL+ ++ +
Sbjct: 5 IPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEE---VSHL 61
Query: 207 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 386
H W+G ++S+DE GA A+L V+L+ + VQHREVQ ES F+ YF ++Y +GG
Sbjct: 62 HLWIGQQSSRDEQGACAVLAVHLNTLLGE-RPVQHREVQGNESDLFMSYFPRGLKYQEGG 120
Query: 387 HASGFSHVTINEGTE-KRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGE 563
S F + K+L+Q+KGK+N+R + ++S N GDCFILD+ IF + G
Sbjct: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGG 180
Query: 564 KAKGVERMKALTVANQIKDQDHNGRADIEV 653
K+ +ER KA +A I+D + G+A +E+
Sbjct: 181 KSNILERNKARDLALAIRDSERQGKAQVEI 210
>U12026-1|AAA92670.1| 172|Homo sapiens Cap-G protein.
Length = 172
Score = 133 bits (321), Expect = 7e-31
Identities = 66/170 (38%), Positives = 102/170 (60%), Gaps = 1/170 (0%)
Frame = +3
Query: 27 MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 206
+P+ F + + PGL +WR+E +PV V + G+F+SGDSY+VL+ ++ +
Sbjct: 5 IPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEE---VSHL 61
Query: 207 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 386
H W+G ++S+DE GA A+L V+L + VQHREVQ ES F+ YF ++Y +GG
Sbjct: 62 HLWIGQQSSRDEQGACAVLAVHL-NTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG 120
Query: 387 HASGFSHVTIN-EGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDV 533
S F + K+L+Q+KGK+N+R + ++S N GDCFILD+
Sbjct: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDL 170
>U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein.
Length = 1269
Score = 125 bits (301), Expect = 2e-28
Identities = 73/200 (36%), Positives = 110/200 (55%), Gaps = 2/200 (1%)
Frame = +3
Query: 54 DAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNT-TGDKDRLTWDIHFWLGSRT 230
D G+ PGL IW+IENF PV V + G FY D YIVL T D L W+I++W+G
Sbjct: 494 DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 553
Query: 231 SQDEAGAAAILTVNLDDEQFQGSAVQH-REVQYYESKEFLEYFSPAIRYLKGGHASGFSH 407
+ D+ +AI VNL + G+ + RE ES+EFL+ F I Y++GG ASGF +
Sbjct: 554 TLDKKACSAIHAVNL--RNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGF-Y 610
Query: 408 VTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERM 587
+ R++++ GK+N++++ V SL+ F+LD I+V+ G +A
Sbjct: 611 TVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTT 670
Query: 588 KALTVANQIKDQDHNGRADI 647
KA A +I + G+A+I
Sbjct: 671 KARLFAEKINKNERKGKAEI 690
>U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog protein.
Length = 1268
Score = 125 bits (301), Expect = 2e-28
Identities = 73/200 (36%), Positives = 110/200 (55%), Gaps = 2/200 (1%)
Frame = +3
Query: 54 DAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNT-TGDKDRLTWDIHFWLGSRT 230
D G+ PGL IW+IENF PV V + G FY D YIVL T D L W+I++W+G
Sbjct: 493 DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 552
Query: 231 SQDEAGAAAILTVNLDDEQFQGSAVQH-REVQYYESKEFLEYFSPAIRYLKGGHASGFSH 407
+ D+ +AI VNL + G+ + RE ES+EFL+ F I Y++GG ASGF +
Sbjct: 553 TLDKKACSAIHAVNL--RNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGF-Y 609
Query: 408 VTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERM 587
+ R++++ GK+N++++ V SL+ F+LD I+V+ G +A
Sbjct: 610 TVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTT 669
Query: 588 KALTVANQIKDQDHNGRADI 647
KA A +I + G+A+I
Sbjct: 670 KARLFAEKINKNERKGKAEI 689
>BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog
(Drosophila) protein.
Length = 1269
Score = 125 bits (301), Expect = 2e-28
Identities = 73/200 (36%), Positives = 110/200 (55%), Gaps = 2/200 (1%)
Frame = +3
Query: 54 DAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNT-TGDKDRLTWDIHFWLGSRT 230
D G+ PGL IW+IENF PV V + G FY D YIVL T D L W+I++W+G
Sbjct: 494 DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 553
Query: 231 SQDEAGAAAILTVNLDDEQFQGSAVQH-REVQYYESKEFLEYFSPAIRYLKGGHASGFSH 407
+ D+ +AI VNL + G+ + RE ES+EFL+ F I Y++GG ASGF +
Sbjct: 554 TLDKKACSAIHAVNL--RNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGF-Y 610
Query: 408 VTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERM 587
+ R++++ GK+N++++ V SL+ F+LD I+V+ G +A
Sbjct: 611 TVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTT 670
Query: 588 KALTVANQIKDQDHNGRADI 647
KA A +I + G+A+I
Sbjct: 671 KARLFAEKINKNERKGKAEI 690
>AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog variant
protein.
Length = 1101
Score = 125 bits (301), Expect = 2e-28
Identities = 73/200 (36%), Positives = 110/200 (55%), Gaps = 2/200 (1%)
Frame = +3
Query: 54 DAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNT-TGDKDRLTWDIHFWLGSRT 230
D G+ PGL IW+IENF PV V + G FY D YIVL T D L W+I++W+G
Sbjct: 481 DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 540
Query: 231 SQDEAGAAAILTVNLDDEQFQGSAVQH-REVQYYESKEFLEYFSPAIRYLKGGHASGFSH 407
+ D+ +AI VNL + G+ + RE ES+EFL+ F I Y++GG ASGF +
Sbjct: 541 TLDKKACSAIHAVNL--RNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGF-Y 597
Query: 408 VTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERM 587
+ R++++ GK+N++++ V SL+ F+LD I+V+ G +A
Sbjct: 598 TVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTT 657
Query: 588 KALTVANQIKDQDHNGRADI 647
KA A +I + G+A+I
Sbjct: 658 KARLFAEKINKNERKGKAEI 677
>AL513122-7|CAI14416.1| 485|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 485
Score = 93.1 bits (221), Expect = 9e-19
Identities = 70/207 (33%), Positives = 99/207 (47%), Gaps = 4/207 (1%)
Frame = +3
Query: 78 EIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAAA 257
+IWRIE V V +G FY GDSYI+L R I+ W G++++QDE A+A
Sbjct: 179 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASA 238
Query: 258 ILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYLKGGHASGFSHVTINEGTE 431
ILT L DE+ G+ VQ R VQ E + F P I Y KGG S T T
Sbjct: 239 ILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIY-KGG-TSREGGQTAPAST- 294
Query: 432 KRLFQIKGKR--NVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVA 605
RLFQ++ R +V P +LN+ D F+L +++VG A E+ A +
Sbjct: 295 -RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELL 353
Query: 606 NQIKDQDHNGRADIEVGDSEAHDGSFE 686
++ Q ++V + DG +E
Sbjct: 354 RVLRAQ------PVQVAEGSEPDGFWE 374
Score = 30.3 bits (65), Expect = 6.8
Identities = 14/35 (40%), Positives = 22/35 (62%)
Frame = +3
Query: 495 ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALT 599
E L D +LD Q+FV+VG+ ++ E+ +ALT
Sbjct: 422 EDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALT 456
>AK075198-1|BAC11465.1| 396|Homo sapiens protein ( Homo sapiens
cDNA FLJ90717 fis, clone PLACE1008657, highly similar to
Bovine mRNA for adseverin. ).
Length = 396
Score = 81.0 bits (191), Expect = 4e-15
Identities = 68/206 (33%), Positives = 98/206 (47%), Gaps = 7/206 (3%)
Frame = +3
Query: 21 PKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTW 200
P+M H D K +EIWR+EN + V + +G FY GD YI+L T + ++
Sbjct: 63 PQMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI-- 117
Query: 201 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRY 374
I+ W G+ ++DE +A LTV L D G AVQ R Q E L F P I Y
Sbjct: 118 -IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIY 175
Query: 375 LKGGHASGFSHVTINEGTEKRLFQIKGKRNV----RVKQVKPTFESLNNGDCFILDV-DH 539
G G RLFQ+ +RN+ R+ +V SLN+ D F+L + +
Sbjct: 176 KNGTSKKGGQ----APAPPTRLFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLPQN 229
Query: 540 QIFVFVGEKAKGVERMKALTVANQIK 617
+++VG+ A E A VA+ +K
Sbjct: 230 SGYIWVGKGASQEEEKGAEYVASVLK 255
Score = 35.9 bits (79), Expect = 0.14
Identities = 17/50 (34%), Positives = 28/50 (56%)
Frame = +3
Query: 489 TFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVANQIKDQDHNGR 638
T + L D +LD QIF+++G+ A VE+ ++L A + D +GR
Sbjct: 317 TQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGR 366
>AK027778-1|BAB55361.1| 468|Homo sapiens protein ( Homo sapiens
cDNA FLJ14872 fis, clone PLACE1002655, highly similar to
ADSEVERIN. ).
Length = 468
Score = 81.0 bits (191), Expect = 4e-15
Identities = 68/206 (33%), Positives = 98/206 (47%), Gaps = 7/206 (3%)
Frame = +3
Query: 21 PKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTW 200
P+M H D K +EIWR+EN + V + +G FY GD YI+L T + ++
Sbjct: 135 PQMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI-- 189
Query: 201 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRY 374
I+ W G+ ++DE +A LTV L D G AVQ R Q E L F P I Y
Sbjct: 190 -IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIY 247
Query: 375 LKGGHASGFSHVTINEGTEKRLFQIKGKRNV----RVKQVKPTFESLNNGDCFILDV-DH 539
G G RLFQ+ +RN+ R+ +V SLN+ D F+L + +
Sbjct: 248 KNGTSKKGGQ----APAPPTRLFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLPQN 301
Query: 540 QIFVFVGEKAKGVERMKALTVANQIK 617
+++VG+ A E A VA+ +K
Sbjct: 302 SGYIWVGKGASQEEEKGAEYVASVLK 327
Score = 35.9 bits (79), Expect = 0.14
Identities = 17/50 (34%), Positives = 28/50 (56%)
Frame = +3
Query: 489 TFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVANQIKDQDHNGR 638
T + L D +LD QIF+++G+ A VE+ ++L A + D +GR
Sbjct: 389 TQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGR 438
>BC075797-1|AAH75797.1| 85|Homo sapiens Unknown (protein for
MGC:87550) protein.
Length = 85
Score = 72.5 bits (170), Expect = 1e-12
Identities = 30/61 (49%), Positives = 42/61 (68%)
Frame = +3
Query: 39 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 218
H+ FA AG++ GL++WRIE E V VP++ G FY GD+Y+VL+T T+ +HFWL
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWL 66
Query: 219 G 221
G
Sbjct: 67 G 67
>X07066-1|CAA30102.1| 69|Homo sapiens protein ( Human gene for
gelsolin exon 4. ).
Length = 69
Score = 71.3 bits (167), Expect = 3e-12
Identities = 28/62 (45%), Positives = 44/62 (70%), Gaps = 1/62 (1%)
Frame = +3
Query: 39 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 215
H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++ L +D+H+W
Sbjct: 8 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 67
Query: 216 LG 221
LG
Sbjct: 68 LG 69
>D88154-1|BAA21668.1| 686|Homo sapiens villin-like protein protein.
Length = 686
Score = 62.5 bits (145), Expect = 1e-09
Identities = 55/205 (26%), Positives = 85/205 (41%), Gaps = 5/205 (2%)
Frame = +3
Query: 15 TRPKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRL 194
T+PK+ + D K +E+W I++ V + G +G+ Y+VL T R+
Sbjct: 205 TQPKLAAQLRMVDDGSGK--VEVWCIQDLHRQPVDPKRHGQLCAGNCYLVLYTYQRLGRV 262
Query: 195 TWDIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRY 374
+ ++ W G + + DE A L D + G VQ E FL F +
Sbjct: 263 QYILYLWQGHQATADEIEALNSNAEEL-DVMYGGVLVQEHVTMGSEPPHFLAIFQGQLVI 321
Query: 375 LK---GGHASGFSHVTINEGTEKRLFQIKG--KRNVRVKQVKPTFESLNNGDCFILDVDH 539
+ G H G S T RLFQ++G N R +V SLN+ D F+L
Sbjct: 322 FQERAGHHGKGQSAST------TRLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTAS 375
Query: 540 QIFVFVGEKAKGVERMKALTVANQI 614
+++ G+ G +R A V I
Sbjct: 376 VCYLWFGKGCNGDQREMARVVVTVI 400
>BC004300-1|AAH04300.1| 672|Homo sapiens VILL protein protein.
Length = 672
Score = 62.5 bits (145), Expect = 1e-09
Identities = 55/205 (26%), Positives = 85/205 (41%), Gaps = 5/205 (2%)
Frame = +3
Query: 15 TRPKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRL 194
T+PK+ + D K +E+W I++ V + G +G+ Y+VL T R+
Sbjct: 191 TQPKLAAQLRMVDDGSGK--VEVWCIQDLHRQPVDPKRHGQLCAGNCYLVLYTYQRLGRV 248
Query: 195 TWDIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRY 374
+ ++ W G + + DE A L D + G VQ E FL F +
Sbjct: 249 QYILYLWQGHQATADEIEALNSNAEEL-DVMYGGVLVQEHVTMGSEPPHFLAIFQGQLVI 307
Query: 375 LK---GGHASGFSHVTINEGTEKRLFQIKG--KRNVRVKQVKPTFESLNNGDCFILDVDH 539
+ G H G S T RLFQ++G N R +V SLN+ D F+L
Sbjct: 308 FQERAGHHGKGQSAST------TRLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTAS 361
Query: 540 QIFVFVGEKAKGVERMKALTVANQI 614
+++ G+ G +R A V I
Sbjct: 362 VCYLWFGKGCNGDQREMARVVVTVI 386
>BC000243-1|AAH00243.1| 686|Homo sapiens VILL protein protein.
Length = 686
Score = 62.5 bits (145), Expect = 1e-09
Identities = 55/205 (26%), Positives = 85/205 (41%), Gaps = 5/205 (2%)
Frame = +3
Query: 15 TRPKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRL 194
T+PK+ + D K +E+W I++ V + G +G+ Y+VL T R+
Sbjct: 205 TQPKLAAQLRMVDDGSGK--VEVWCIQDLHRQPVDPKRHGQLCAGNCYLVLYTYQRLGRV 262
Query: 195 TWDIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRY 374
+ ++ W G + + DE A L D + G VQ E FL F +
Sbjct: 263 QYILYLWQGHQATADEIEALNSNAEEL-DVMYGGVLVQEHVTMGSEPPHFLAIFQGQLVI 321
Query: 375 LK---GGHASGFSHVTINEGTEKRLFQIKG--KRNVRVKQVKPTFESLNNGDCFILDVDH 539
+ G H G S T RLFQ++G N R +V SLN+ D F+L
Sbjct: 322 FQERAGHHGKGQSAST------TRLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTAS 375
Query: 540 QIFVFVGEKAKGVERMKALTVANQI 614
+++ G+ G +R A V I
Sbjct: 376 VCYLWFGKGCNGDQREMARVVVTVI 400
>AL160060-2|CAH71300.1| 2214|Homo sapiens supervillin protein.
Length = 2214
Score = 57.6 bits (133), Expect(2) = 2e-08
Identities = 28/66 (42%), Positives = 43/66 (65%)
Frame = +3
Query: 438 LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVANQIK 617
L QIKG+R+V+ + V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
Query: 618 DQDHNG 635
+ G
Sbjct: 1505 TKRELG 1510
Score = 50.4 bits (115), Expect = 6e-06
Identities = 53/203 (26%), Positives = 94/203 (46%), Gaps = 20/203 (9%)
Frame = +3
Query: 75 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 209
+++W I F+ +PK G F+ GD+Y+V G + + +
Sbjct: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813
Query: 210 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 386
FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F +
Sbjct: 1814 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1865
Query: 387 HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 554
H+ N +E RL+ ++G+ V + +V SL + +L+V+ I+++
Sbjct: 1866 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1925
Query: 555 VGEKAKGVERMKALTVANQIKDQ 623
G KA+ + T AN+IK+Q
Sbjct: 1926 HGCKAQAHTKEVGRTAANKIKEQ 1948
Score = 20.6 bits (41), Expect(2) = 2e-08
Identities = 9/41 (21%), Positives = 20/41 (48%)
Frame = +3
Query: 216 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 338
L S++ ++ +VNL ++ SAV ++ + + K
Sbjct: 1409 LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1449
>AL158167-3|CAI15237.1| 2214|Homo sapiens supervillin protein.
Length = 2214
Score = 57.6 bits (133), Expect(2) = 2e-08
Identities = 28/66 (42%), Positives = 43/66 (65%)
Frame = +3
Query: 438 LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVANQIK 617
L QIKG+R+V+ + V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
Query: 618 DQDHNG 635
+ G
Sbjct: 1505 TKRELG 1510
Score = 50.4 bits (115), Expect = 6e-06
Identities = 53/203 (26%), Positives = 94/203 (46%), Gaps = 20/203 (9%)
Frame = +3
Query: 75 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 209
+++W I F+ +PK G F+ GD+Y+V G + + +
Sbjct: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813
Query: 210 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 386
FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F +
Sbjct: 1814 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1865
Query: 387 HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 554
H+ N +E RL+ ++G+ V + +V SL + +L+V+ I+++
Sbjct: 1866 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1925
Query: 555 VGEKAKGVERMKALTVANQIKDQ 623
G KA+ + T AN+IK+Q
Sbjct: 1926 HGCKAQAHTKEVGRTAANKIKEQ 1948
Score = 20.6 bits (41), Expect(2) = 2e-08
Identities = 9/41 (21%), Positives = 20/41 (48%)
Frame = +3
Query: 216 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 338
L S++ ++ +VNL ++ SAV ++ + + K
Sbjct: 1409 LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1449
>AF109135-1|AAD14682.1| 2214|Homo sapiens archvillin protein.
Length = 2214
Score = 57.6 bits (133), Expect(2) = 2e-08
Identities = 28/66 (42%), Positives = 43/66 (65%)
Frame = +3
Query: 438 LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVANQIK 617
L QIKG+R+V+ + V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
Query: 618 DQDHNG 635
+ G
Sbjct: 1505 TKRELG 1510
Score = 50.4 bits (115), Expect = 6e-06
Identities = 53/203 (26%), Positives = 94/203 (46%), Gaps = 20/203 (9%)
Frame = +3
Query: 75 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 209
+++W I F+ +PK G F+ GD+Y+V G + + +
Sbjct: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813
Query: 210 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 386
FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F +
Sbjct: 1814 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1865
Query: 387 HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 554
H+ N +E RL+ ++G+ V + +V SL + +L+V+ I+++
Sbjct: 1866 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1925
Query: 555 VGEKAKGVERMKALTVANQIKDQ 623
G KA+ + T AN+IK+Q
Sbjct: 1926 HGCKAQAHTKEVGRTAANKIKEQ 1948
Score = 20.6 bits (41), Expect(2) = 2e-08
Identities = 9/41 (21%), Positives = 20/41 (48%)
Frame = +3
Query: 216 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 338
L S++ ++ +VNL ++ SAV ++ + + K
Sbjct: 1409 LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1449
>AL160060-1|CAH71301.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 57.6 bits (133), Expect(2) = 2e-08
Identities = 28/66 (42%), Positives = 43/66 (65%)
Frame = +3
Query: 438 LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVANQIK 617
L QIKG+R+V+ + V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 618 DQDHNG 635
+ G
Sbjct: 1079 TKRELG 1084
Score = 50.4 bits (115), Expect = 6e-06
Identities = 53/203 (26%), Positives = 94/203 (46%), Gaps = 20/203 (9%)
Frame = +3
Query: 75 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 209
+++W I F+ +PK G F+ GD+Y+V G + + +
Sbjct: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387
Query: 210 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 386
FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F +
Sbjct: 1388 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1439
Query: 387 HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 554
H+ N +E RL+ ++G+ V + +V SL + +L+V+ I+++
Sbjct: 1440 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1499
Query: 555 VGEKAKGVERMKALTVANQIKDQ 623
G KA+ + T AN+IK+Q
Sbjct: 1500 HGCKAQAHTKEVGRTAANKIKEQ 1522
Score = 20.6 bits (41), Expect(2) = 2e-08
Identities = 9/41 (21%), Positives = 20/41 (48%)
Frame = +3
Query: 216 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 338
L S++ ++ +VNL ++ SAV ++ + + K
Sbjct: 983 LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1023
>AL158167-2|CAI15236.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 57.6 bits (133), Expect(2) = 2e-08
Identities = 28/66 (42%), Positives = 43/66 (65%)
Frame = +3
Query: 438 LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVANQIK 617
L QIKG+R+V+ + V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 618 DQDHNG 635
+ G
Sbjct: 1079 TKRELG 1084
Score = 50.4 bits (115), Expect = 6e-06
Identities = 53/203 (26%), Positives = 94/203 (46%), Gaps = 20/203 (9%)
Frame = +3
Query: 75 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 209
+++W I F+ +PK G F+ GD+Y+V G + + +
Sbjct: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387
Query: 210 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 386
FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F +
Sbjct: 1388 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1439
Query: 387 HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 554
H+ N +E RL+ ++G+ V + +V SL + +L+V+ I+++
Sbjct: 1440 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1499
Query: 555 VGEKAKGVERMKALTVANQIKDQ 623
G KA+ + T AN+IK+Q
Sbjct: 1500 HGCKAQAHTKEVGRTAANKIKEQ 1522
Score = 20.6 bits (41), Expect(2) = 2e-08
Identities = 9/41 (21%), Positives = 20/41 (48%)
Frame = +3
Query: 216 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 338
L S++ ++ +VNL ++ SAV ++ + + K
Sbjct: 983 LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1023
>AF051851-1|AAC64696.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 57.6 bits (133), Expect(2) = 2e-08
Identities = 28/66 (42%), Positives = 43/66 (65%)
Frame = +3
Query: 438 LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVANQIK 617
L QIKG+R+V+ + V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 618 DQDHNG 635
+ G
Sbjct: 1079 TKRELG 1084
Score = 50.4 bits (115), Expect = 6e-06
Identities = 53/203 (26%), Positives = 94/203 (46%), Gaps = 20/203 (9%)
Frame = +3
Query: 75 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 209
+++W I F+ +PK G F+ GD+Y+V G + + +
Sbjct: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387
Query: 210 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 386
FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F +
Sbjct: 1388 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1439
Query: 387 HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 554
H+ N +E RL+ ++G+ V + +V SL + +L+V+ I+++
Sbjct: 1440 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1499
Query: 555 VGEKAKGVERMKALTVANQIKDQ 623
G KA+ + T AN+IK+Q
Sbjct: 1500 HGCKAQAHTKEVGRTAANKIKEQ 1522
Score = 20.6 bits (41), Expect(2) = 2e-08
Identities = 9/41 (21%), Positives = 20/41 (48%)
Frame = +3
Query: 216 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 338
L S++ ++ +VNL ++ SAV ++ + + K
Sbjct: 983 LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1023
>AF051850-1|AAC64695.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 57.6 bits (133), Expect(2) = 2e-08
Identities = 28/66 (42%), Positives = 43/66 (65%)
Frame = +3
Query: 438 LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVANQIK 617
L QIKG+R+V+ + V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 618 DQDHNG 635
+ G
Sbjct: 1079 TKRELG 1084
Score = 50.4 bits (115), Expect = 6e-06
Identities = 53/203 (26%), Positives = 94/203 (46%), Gaps = 20/203 (9%)
Frame = +3
Query: 75 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 209
+++W I F+ +PK G F+ GD+Y+V G + + +
Sbjct: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387
Query: 210 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 386
FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F +
Sbjct: 1388 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1439
Query: 387 HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 554
H+ N +E RL+ ++G+ V + +V SL + +L+V+ I+++
Sbjct: 1440 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1499
Query: 555 VGEKAKGVERMKALTVANQIKDQ 623
G KA+ + T AN+IK+Q
Sbjct: 1500 HGCKAQAHTKEVGRTAANKIKEQ 1522
Score = 20.6 bits (41), Expect(2) = 2e-08
Identities = 9/41 (21%), Positives = 20/41 (48%)
Frame = +3
Query: 216 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 338
L S++ ++ +VNL ++ SAV ++ + + K
Sbjct: 983 LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1023
>BC017491-1|AAH17491.1| 285|Homo sapiens Similar to gelsolin
(amyloidosis, Finnish type) protein.
Length = 285
Score = 56.0 bits (129), Expect = 1e-07
Identities = 50/157 (31%), Positives = 73/157 (46%), Gaps = 4/157 (2%)
Frame = +3
Query: 228 TSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYLKGGHASGF 401
++QDE A+AILT L DE+ G+ VQ R VQ E + F P I Y KGG S
Sbjct: 1 STQDEVAASAILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIY-KGG-TSRE 57
Query: 402 SHVTINEGTEKRLFQIKGKR--NVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKG 575
T T RLFQ++ R +V P +LN+ D F+L +++VG A
Sbjct: 58 GGQTAPAST--RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASE 115
Query: 576 VERMKALTVANQIKDQDHNGRADIEVGDSEAHDGSFE 686
E+ A + ++ Q ++V + DG +E
Sbjct: 116 AEKTGAQELLRVLRAQ------PVQVAEGSEPDGFWE 146
Score = 33.1 bits (72), Expect = 0.97
Identities = 17/48 (35%), Positives = 27/48 (56%)
Frame = +3
Query: 495 ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVANQIKDQDHNGR 638
E L D +LD Q+FV+VG+ ++ E+ +ALT A + + D R
Sbjct: 194 EDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANR 241
>AK092426-1|BAC03887.1| 258|Homo sapiens protein ( Homo sapiens
cDNA FLJ35107 fis, clone PLACE6006871, moderately
similar to SUPPRESSOR PROTEIN SRP40. ).
Length = 258
Score = 35.9 bits (79), Expect = 0.14
Identities = 38/142 (26%), Positives = 65/142 (45%), Gaps = 3/142 (2%)
Frame = +1
Query: 61 AGSRVSKYGGLRTSNRSPFRRLSSV---SSTPGTPTLY*TPQAIRTV*HGTSISGSARGP 231
AG GG R+S+ S LSS SS P + + +P + + S S S+ P
Sbjct: 25 AGPNALGSGGSRSSSSSSRSILSSSILSSSIPSSSSSSSSPSSSHSS-SSPSSSHSSSSP 83
Query: 232 ARTKPARRPSSR*TWTTNNSKDQRYSTERSNITSPRSS*NISHQPSAI*KADTPQASAT* 411
+ + PSS + ++++S S+ S+ +SP SS + S S + +P +S++
Sbjct: 84 SSSSSTSSPSSSSSSSSSSSPSSSNSSSSSSSSSPSSS-SSSSSSSPSSSSSSPSSSSSS 142
Query: 412 RSMREQRNDSSRSRVKETSALS 477
S + SS S +S+ S
Sbjct: 143 SSSSPSSSSSSPSSSSSSSSSS 164
>BC117319-1|AAI17320.1| 257|Homo sapiens TPRXL protein protein.
Length = 257
Score = 33.5 bits (73), Expect = 0.73
Identities = 36/142 (25%), Positives = 64/142 (45%), Gaps = 3/142 (2%)
Frame = +1
Query: 61 AGSRVSKYGGLRTSNRSPFRRLSSV---SSTPGTPTLY*TPQAIRTV*HGTSISGSARGP 231
AG GG R+S+ S LSS SS P + + +P + + S S S+ P
Sbjct: 25 AGPNALGSGGSRSSSSSSRSILSSSILSSSIPSSSSSSSSPSSSHSS-SSPSSSHSSSSP 83
Query: 232 ARTKPARRPSSR*TWTTNNSKDQRYSTERSNITSPRSS*NISHQPSAI*KADTPQASAT* 411
+ + PSS + ++++ S+ S+ + SS + S PS+ + +P +S++
Sbjct: 84 SSSSSTSSPSSSSSSSSSSPSSSNSSSSSSSSSPSSSSSSSSSSPSS--SSSSPSSSSSS 141
Query: 412 RSMREQRNDSSRSRVKETSALS 477
S + SS S +S+ S
Sbjct: 142 SSSSPSSSSSSPSSSSSSSSSS 163
>AL513122-9|CAI14417.1| 207|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 207
Score = 33.1 bits (72), Expect = 0.97
Identities = 17/48 (35%), Positives = 27/48 (56%)
Frame = +3
Query: 495 ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKALTVANQIKDQDHNGR 638
E L D +LD Q+FV+VG+ ++ E+ +ALT A + + D R
Sbjct: 116 EDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANR 163
>BC106877-1|AAI06878.1| 663|Homo sapiens chromosome 1 open reading
frame 106 protein.
Length = 663
Score = 31.9 bits (69), Expect = 2.2
Identities = 22/69 (31%), Positives = 33/69 (47%)
Frame = -1
Query: 397 PEACPPFK*RMAGEKYSRNSLDS*YWTSRCCTADPWNCSSSKFTVRMAAAPASSWLVLEP 218
PEA P + + + SLD Y R +++PW+ SSS T ASS +LEP
Sbjct: 309 PEAGSPERAPVQNSPWKETSLDHPYEKPRK-SSEPWSESSSPATTPQDGPSASSLWLLEP 367
Query: 217 SQKWMSHVR 191
+ + +R
Sbjct: 368 ASYHVVPIR 376
>AK001763-1|BAA91892.1| 663|Homo sapiens protein ( Homo sapiens
cDNA FLJ10901 fis, clone NT2RP5003524. ).
Length = 663
Score = 31.9 bits (69), Expect = 2.2
Identities = 22/69 (31%), Positives = 33/69 (47%)
Frame = -1
Query: 397 PEACPPFK*RMAGEKYSRNSLDS*YWTSRCCTADPWNCSSSKFTVRMAAAPASSWLVLEP 218
PEA P + + + SLD Y R +++PW+ SSS T ASS +LEP
Sbjct: 309 PEAGSPERAPVQNSPWKETSLDHPYEKPRK-SSEPWSESSSPATTPQDGPSASSLWLLEP 367
Query: 217 SQKWMSHVR 191
+ + +R
Sbjct: 368 ASYHVVPIR 376
>AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ
protein protein.
Length = 3222
Score = 30.7 bits (66), Expect = 5.2
Identities = 21/61 (34%), Positives = 29/61 (47%), Gaps = 5/61 (8%)
Frame = +3
Query: 486 PTFESLNNGDCFILDVDHQ--IFV---FVGEKAKGVERMKALTVANQIKDQDHNGRADIE 650
P F S D +LDV+ IF F+ E + + K LTV+ KD NG+ D E
Sbjct: 945 PPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPRKILTVSAMDKDSGPNGQLDYE 1004
Query: 651 V 653
+
Sbjct: 1005 I 1005
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 107,331,566
Number of Sequences: 237096
Number of extensions: 2334613
Number of successful extensions: 5837
Number of sequences better than 10.0: 47
Number of HSP's better than 10.0 without gapping: 5416
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5764
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7951235188
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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