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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= epV31104
         (606 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri...   230   2e-59
UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA...   180   2e-44
UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ...   179   4e-44
UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu...   171   1e-41
UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p...   162   7e-39
UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13...   155   6e-37
UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R...   155   1e-36
UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ...   153   4e-36
UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1...   153   4e-36
UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|...   151   9e-36
UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep...   151   9e-36
UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18...   151   1e-35
UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal...   151   2e-35
UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve...   150   2e-35
UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ...   146   3e-34
UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct...   146   5e-34
UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons...   146   5e-34
UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ...   145   6e-34
UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi...   145   8e-34
UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ...   144   1e-33
UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|...   143   3e-33
UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep...   143   3e-33
UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;...   143   3e-33
UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r...   142   4e-33
UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ...   142   6e-33
UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta...   142   6e-33
UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:...   141   1e-32
UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor...   141   1e-32
UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica...   140   2e-32
UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n...   140   2e-32
UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R...   139   5e-32
UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta...   139   5e-32
UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio...   138   7e-32
UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt...   138   7e-32
UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ...   138   9e-32
UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ...   138   9e-32
UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb...   138   1e-31
UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac...   137   2e-31
UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ...   136   3e-31
UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ...   136   3e-31
UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi...   136   5e-31
UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti...   136   5e-31
UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E...   136   5e-31
UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;...   135   9e-31
UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ...   134   1e-30
UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;...   134   2e-30
UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+...   134   2e-30
UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d...   133   3e-30
UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ...   133   4e-30
UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;...   133   4e-30
UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin...   132   5e-30
UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ...   132   5e-30
UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7...   132   6e-30
UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste...   132   8e-30
UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac...   131   1e-29
UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re...   131   1e-29
UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;...   130   2e-29
UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A...   130   2e-29
UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium...   130   2e-29
UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7...   130   3e-29
UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ...   129   4e-29
UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ...   129   6e-29
UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org...   129   6e-29
UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re...   128   1e-28
UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|...   128   1e-28
UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or...   128   1e-28
UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r...   127   2e-28
UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota...   127   2e-28
UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam...   127   2e-28
UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:...   127   2e-28
UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled...   127   2e-28
UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ...   127   2e-28
UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam...   127   2e-28
UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+...   127   2e-28
UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam...   126   3e-28
UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ...   126   4e-28
UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R...   126   5e-28
UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str...   125   7e-28
UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc...   125   9e-28
UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re...   125   9e-28
UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam...   124   1e-27
UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di...   124   1e-27
UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald...   124   1e-27
UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA...   124   2e-27
UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=...   124   2e-27
UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ...   124   2e-27
UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27...   124   2e-27
UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep...   123   3e-27
UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb...   123   4e-27
UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ...   122   7e-27
UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=...   122   7e-27
UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt...   122   7e-27
UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li...   121   1e-26
UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n...   121   1e-26
UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria...   121   1e-26
UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ...   120   3e-26
UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ...   120   4e-26
UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm...   119   5e-26
UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;...   119   5e-26
UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB...   119   5e-26
UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve...   119   5e-26
UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:...   119   6e-26
UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac...   119   6e-26
UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ...   119   6e-26
UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ...   118   8e-26
UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy...   118   8e-26
UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam...   118   1e-25
UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ...   118   1e-25
UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E...   118   1e-25
UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=...   118   1e-25
UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ...   118   1e-25
UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ...   117   2e-25
UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str...   117   2e-25
UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=...   117   2e-25
UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ...   117   2e-25
UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;...   117   2e-25
UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea...   117   2e-25
UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ...   116   3e-25
UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop...   116   4e-25
UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;...   116   4e-25
UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re...   116   6e-25
UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct...   115   8e-25
UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l...   115   8e-25
UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:...   115   1e-24
UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ...   115   1e-24
UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase...   115   1e-24
UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct...   114   1e-24
UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct...   114   2e-24
UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;...   114   2e-24
UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r...   114   2e-24
UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom...   114   2e-24
UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam...   114   2e-24
UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct...   113   3e-24
UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:...   113   4e-24
UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red...   113   4e-24
UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba...   113   4e-24
UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ...   112   5e-24
UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami...   112   5e-24
UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r...   112   5e-24
UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re...   112   5e-24
UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r...   112   7e-24
UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam...   112   7e-24
UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li...   111   1e-23
UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4...   111   1e-23
UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ...   111   1e-23
UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium...   111   1e-23
UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=...   111   1e-23
UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;...   111   2e-23
UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter...   111   2e-23
UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh...   111   2e-23
UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri...   102   2e-23
UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta...   110   2e-23
UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy...   110   2e-23
UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal...   110   3e-23
UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10...   110   3e-23
UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several...   110   3e-23
UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam...   109   4e-23
UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|...   109   4e-23
UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red...   109   7e-23
UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li...   109   7e-23
UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti...   109   7e-23
UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil...   109   7e-23
UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ...   109   7e-23
UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ...   108   9e-23
UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ...   108   1e-22
UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;...   107   3e-22
UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop...   107   3e-22
UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno...   107   3e-22
UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S...   107   3e-22
UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep...   106   5e-22
UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ...   106   5e-22
UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba...   106   5e-22
UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ...   106   5e-22
UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag...   106   5e-22
UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ...   106   5e-22
UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep...   105   6e-22
UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ...   105   6e-22
UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ...   105   8e-22
UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;...   105   8e-22
UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ...   104   1e-21
UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ...   104   1e-21
UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea...   104   2e-21
UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n...   103   3e-21
UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ...   103   3e-21
UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1...   103   4e-21
UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci...   103   4e-21
UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ...   103   4e-21
UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3...   103   4e-21
UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar...   102   6e-21
UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl...   102   8e-21
UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ...   102   8e-21
UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ...   101   1e-20
UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ...   101   1e-20
UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;...   101   2e-20
UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ...   100   2e-20
UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ...   100   3e-20
UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ...   100   3e-20
UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re...    99   4e-20
UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ...    86   4e-20
UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ...   100   5e-20
UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str...   100   5e-20
UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:...    99   7e-20
UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas...    99   9e-20
UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba...    99   9e-20
UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam...    98   1e-19
UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101...    98   2e-19
UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob...    97   2e-19
UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini...    97   3e-19
UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte...    97   3e-19
UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l...    97   3e-19
UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ...    97   4e-19
UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n...    97   4e-19
UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O...    96   5e-19
UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam...    96   7e-19
UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri...    96   7e-19
UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami...    96   7e-19
UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1...    95   1e-18
UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra...    95   2e-18
UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ...    95   2e-18
UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct...    94   2e-18
UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n...    94   3e-18
UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=...    94   3e-18
UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter...    93   4e-18
UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve...    93   4e-18
UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re...    93   4e-18
UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ...    93   4e-18
UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la...    93   4e-18
UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec...    92   8e-18
UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,...    91   2e-17
UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ...    91   2e-17
UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ...    91   2e-17
UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ...    91   2e-17
UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ...    91   2e-17
UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ...    90   4e-17
UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ...    89   6e-17
UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam...    89   8e-17
UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r...    89   8e-17
UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ...    89   8e-17
UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ...    89   1e-16
UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace...    89   1e-16
UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ...    89   1e-16
UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi...    88   1e-16
UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc...    88   1e-16
UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra...    88   2e-16
UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba...    88   2e-16
UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam...    88   2e-16
UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ...    87   2e-16
UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act...    87   3e-16
UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;...    86   7e-16
UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ...    86   7e-16
UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ...    86   7e-16
UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la...    86   7e-16
UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc...    85   9e-16
UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ...    85   1e-15
UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ...    85   2e-15
UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami...    84   2e-15
UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc...    84   3e-15
UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la...    84   3e-15
UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try...    83   4e-15
UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo...    83   5e-15
UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=...    82   9e-15
UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac...    82   9e-15
UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1...    82   1e-14
UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez...    82   1e-14
UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl...    81   2e-14
UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc...    81   2e-14
UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik...    81   2e-14
UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet...    81   3e-14
UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami...    79   6e-14
UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ...    79   6e-14
UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ...    79   6e-14
UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve...    79   8e-14
UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v...    79   1e-13
UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep...    79   1e-13
UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,...    78   1e-13
UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac...    78   2e-13
UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri...    78   2e-13
UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe...    77   2e-13
UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac...    77   2e-13
UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei...    77   3e-13
UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil...    77   3e-13
UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ...    77   3e-13
UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ...    76   8e-13
UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium...    75   1e-12
UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;...    75   1e-12
UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ...    75   2e-12
UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica...    63   2e-12
UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;...    74   3e-12
UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc...    74   3e-12
UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta...    73   4e-12
UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ...    73   4e-12
UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami...    73   4e-12
UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ...    73   5e-12
UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto...    73   7e-12
UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere...    71   2e-11
UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez...    71   3e-11
UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ...    70   4e-11
UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n...    70   4e-11
UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054...    69   7e-11
UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ...    69   1e-10
UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella...    68   2e-10
UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The...    68   2e-10
UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep...    68   2e-10
UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc...    67   3e-10
UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ...    66   5e-10
UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam...    66   5e-10
UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ...    66   6e-10
UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D...    66   6e-10
UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ...    66   8e-10
UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ...    65   1e-09
UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017...    65   1e-09
UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom...    64   2e-09
UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc...    64   2e-09
UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta...    64   2e-09
UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ...    64   2e-09
UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam...    64   2e-09
UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|...    64   2e-09
UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata...    64   2e-09
UniRef50_Q9C2J8 Cluster: Related to D-xylose reductase II, III p...    64   3e-09
UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter...    63   4e-09
UniRef50_P80874 Cluster: General stress protein 69; n=16; cellul...    63   6e-09
UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap...    62   7e-09
UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ...    62   1e-08
UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|...    62   1e-08
UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma...    62   1e-08
UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria...    61   2e-08
UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3....    61   2e-08
UniRef50_Q67NQ1 Cluster: Oxidoreductase; n=1; Symbiobacterium th...    60   3e-08
UniRef50_Q88TP1 Cluster: Oxidoreductase; n=3; Bacteria|Rep: Oxid...    60   4e-08
UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga...    59   7e-08
UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ...    59   7e-08
UniRef50_A6X3I0 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:...    59   9e-08
UniRef50_A4RPC9 Cluster: Putative uncharacterized protein; n=1; ...    59   9e-08
UniRef50_Q5KPU6 Cluster: Putative uncharacterized protein; n=2; ...    58   1e-07
UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep...    58   2e-07
UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:...    58   2e-07
UniRef50_A6WAE5 Cluster: Aldo/keto reductase; n=1; Kineococcus r...    58   2e-07
UniRef50_A5VEK4 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:...    58   2e-07
UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob...    58   2e-07
UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact...    58   2e-07
UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ...    58   2e-07
UniRef50_A1CHK2 Cluster: Aldose 1-epimerase, putative; n=11; Pez...    58   2e-07
UniRef50_Q3I1P2 Cluster: Aldo-keto oxidoreductase; n=6; Bacteria...    57   4e-07
UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel...    57   4e-07
UniRef50_P0A9T5 Cluster: Protein tas; n=88; Bacteria|Rep: Protei...    57   4e-07
UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n...    56   5e-07
UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia...    56   5e-07
UniRef50_A7AFQ7 Cluster: Putative uncharacterized protein; n=1; ...    56   5e-07
UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap...    56   5e-07
UniRef50_Q8TTK4 Cluster: Aldo/keto reductase; n=28; cellular org...    56   9e-07
UniRef50_Q89JX0 Cluster: Oxidoreductase; n=26; Bacteria|Rep: Oxi...    55   1e-06
UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac...    55   1e-06
UniRef50_Q0TYC7 Cluster: Predicted protein; n=1; Phaeosphaeria n...    55   2e-06
UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri...    54   2e-06
UniRef50_Q60BI7 Cluster: Oxidoreductase, aldo/keto reductase fam...    54   2e-06
UniRef50_Q08NK7 Cluster: Aldo/keto reductase; n=1; Stigmatella a...    54   2e-06
UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ...    54   2e-06
UniRef50_P77735 Cluster: Uncharacterized oxidoreductase yajO; n=...    54   2e-06
UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r...    54   3e-06
UniRef50_Q88SS2 Cluster: Oxidoreductase; n=13; Firmicutes|Rep: O...    54   3e-06
UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola...    54   3e-06
UniRef50_Q034L5 Cluster: Aryl-alcohol dehydrogenase related enzy...    54   3e-06
UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ...    54   3e-06
UniRef50_UPI0001556575 Cluster: PREDICTED: similar to Aldo-keto ...    54   3e-06
UniRef50_Q3WEJ4 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:...    54   3e-06
UniRef50_Q0RGM0 Cluster: Putative aldoketoreductase; n=2; Franki...    53   5e-06
UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep...    53   5e-06
UniRef50_A0GDL6 Cluster: Aldo/keto reductase; n=1; Burkholderia ...    53   5e-06
UniRef50_UPI000023DAA9 Cluster: hypothetical protein FG00321.1; ...    52   8e-06
UniRef50_Q7NCE7 Cluster: Glr3032 protein; n=5; Cyanobacteria|Rep...    52   1e-05
UniRef50_Q1FGT0 Cluster: Aldo/keto reductase; n=1; Clostridium p...    52   1e-05
UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;...    52   1e-05
UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno...    52   1e-05
UniRef50_A1SJZ0 Cluster: Aldo/keto reductase; n=11; Actinomyceta...    52   1e-05
UniRef50_A0K203 Cluster: Aldo/keto reductase; n=2; Arthrobacter|...    52   1e-05
UniRef50_Q97UG6 Cluster: Oxidoreductase; n=5; Archaea|Rep: Oxido...    52   1e-05
UniRef50_Q983C8 Cluster: Oxido-reductase, and dehydratase; MocA;...    51   2e-05
UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular...    51   2e-05
UniRef50_Q2FGN2 Cluster: Oxidoreductase, aldo/keto reductase fam...    51   2e-05
UniRef50_Q0LKQ4 Cluster: Aldo/keto reductase; n=1; Herpetosiphon...    51   2e-05
UniRef50_A6LWU9 Cluster: Aldo/keto reductase; n=3; Clostridium|R...    51   2e-05
UniRef50_P49261 Cluster: Rho beta-crystallin; n=1; Lepidodactylu...    51   2e-05
UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|...    51   2e-05
UniRef50_Q2J7H2 Cluster: Aldo/keto reductase; n=16; Bacteria|Rep...    51   2e-05
UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy...    51   2e-05
UniRef50_Q1EZH4 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ...    51   2e-05
UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n...    51   2e-05
UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|...    51   2e-05
UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu...    50   3e-05
UniRef50_Q1GSJ8 Cluster: Aldo/keto reductase; n=3; Sphingomonada...    50   3e-05
UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=...    50   3e-05
UniRef50_A7HL79 Cluster: Aldo/keto reductase; n=1; Fervidobacter...    50   4e-05
UniRef50_A5FAZ9 Cluster: Aldo/keto reductase; n=1; Flavobacteriu...    50   4e-05
UniRef50_A3I0G0 Cluster: Oxidoreductase; n=1; Algoriphagus sp. P...    50   4e-05
UniRef50_A0JVH3 Cluster: Aldo/keto reductase; n=17; Bacteria|Rep...    50   4e-05
UniRef50_A7RXR1 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ...    50   4e-05
UniRef50_P54569 Cluster: Uncharacterized oxidoreductase yqkF; n=...    50   4e-05
UniRef50_Q8YAN3 Cluster: Lmo0084 protein; n=11; Listeria monocyt...    50   6e-05
UniRef50_Q7NJD8 Cluster: Gll1894 protein; n=5; Bacteria|Rep: Gll...    50   6e-05
UniRef50_Q74DE6 Cluster: Oxidoreductase, aldo/keto reductase fam...    50   6e-05
UniRef50_A6CMV7 Cluster: Putative uncharacterized protein; n=2; ...    50   6e-05
UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ...    50   6e-05
UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep...    49   7e-05
UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase...    49   7e-05
UniRef50_Q7UL88 Cluster: DTDP-4-keto-L-6-deoxy-hexose 2,3-reduct...    49   7e-05
UniRef50_Q49V75 Cluster: Putative oxidoreductase; n=1; Staphyloc...    49   7e-05
UniRef50_Q1FGT1 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ...    49   7e-05
UniRef50_A1ZPI5 Cluster: Oxidoreductase; n=1; Microscilla marina...    49   7e-05
UniRef50_Q40648 Cluster: Probable voltage-gated potassium channe...    49   7e-05
UniRef50_UPI00003C85A8 Cluster: hypothetical protein Faci_030001...    49   1e-04
UniRef50_Q81RN9 Cluster: Oxidoreductase, aldo/keto reductase fam...    49   1e-04
UniRef50_Q7D3N9 Cluster: AGR_pAT_274p; n=3; Proteobacteria|Rep: ...    49   1e-04
UniRef50_Q1GHE2 Cluster: Aldo/keto reductase; n=8; Alphaproteoba...    49   1e-04
UniRef50_A0YSM3 Cluster: Probable oxidoreductase; n=1; Lyngbya s...    49   1e-04
UniRef50_Q6NKP1 Cluster: At5g53580; n=18; cellular organisms|Rep...    49   1e-04
UniRef50_A6S357 Cluster: Putative uncharacterized protein; n=2; ...    49   1e-04
UniRef50_Q98EU0 Cluster: Oxidoreductase; MocA; n=27; Bacteria|Re...    48   1e-04
UniRef50_A3IX63 Cluster: Putative oxidoreductase; n=1; Cyanothec...    48   1e-04
UniRef50_Q8ZXA1 Cluster: Aldo-keto reductase family protein; n=3...    48   1e-04
UniRef50_A3H9H5 Cluster: Aldo/keto reductase; n=2; Archaea|Rep: ...    48   1e-04
UniRef50_Q94A68 Cluster: Uncharacterized oxidoreductase At1g0669...    48   1e-04
UniRef50_A3TNI0 Cluster: Oxidoreductase, aldo/keto reductase fam...    48   2e-04
UniRef50_A1RJL6 Cluster: Aldo/keto reductase; n=37; Bacteria|Rep...    48   2e-04
UniRef50_Q2H7Q3 Cluster: Putative uncharacterized protein; n=1; ...    48   2e-04
UniRef50_Q39MY8 Cluster: Aldo/keto reductase; n=10; Bacteria|Rep...    48   2e-04
UniRef50_Q6XUT6 Cluster: Oxido-reductase/dehydratase; n=3; Bacte...    48   2e-04
UniRef50_A4QYG8 Cluster: Putative uncharacterized protein; n=1; ...    48   2e-04
UniRef50_A4QYA4 Cluster: Putative uncharacterized protein; n=1; ...    48   2e-04
UniRef50_Q8YXI8 Cluster: All1225 protein; n=9; Cyanobacteria|Rep...    47   3e-04
UniRef50_Q11BU4 Cluster: Aldo/keto reductase; n=11; Proteobacter...    47   3e-04
UniRef50_Q0FFB1 Cluster: Aldo/keto reductase; n=1; alpha proteob...    47   3e-04
UniRef50_A6C9W8 Cluster: Aldo/keto reductase; n=2; Planctomyceta...    47   3e-04
UniRef50_Q8VV02 Cluster: Putative oxidoreductase; n=1; Streptomy...    47   4e-04
UniRef50_Q0LP88 Cluster: Aldo/keto reductase; n=4; Bacteria|Rep:...    47   4e-04
UniRef50_Q9VGF3 Cluster: CG18547-PA; n=7; Endopterygota|Rep: CG1...    47   4e-04
UniRef50_Q4WE64 Cluster: Aldo-keto reductase (AKR), putative; n=...    47   4e-04
UniRef50_Q46851 Cluster: Uncharacterized protein yghZ; n=126; Ba...    47   4e-04
UniRef50_Q8G7F7 Cluster: Possible oxidoreductase of the aldo/ket...    46   5e-04
UniRef50_Q04TM6 Cluster: Aryl-alcohol dehydrogenase-related oxid...    46   5e-04
UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy...    46   5e-04
UniRef50_A7AFU4 Cluster: Putative uncharacterized protein; n=1; ...    46   5e-04
UniRef50_A1SLH1 Cluster: Aldo/keto reductase; n=27; Bacteria|Rep...    46   5e-04
UniRef50_A0VAL7 Cluster: Aldo/keto reductase; n=2; Proteobacteri...    46   5e-04
UniRef50_Q9X0R5 Cluster: Oxidoreductase, aldo/keto reductase fam...    46   7e-04
UniRef50_Q98IA6 Cluster: Aryl-alcohol dehydrogenase; n=1; Mesorh...    46   7e-04
UniRef50_Q1GJE2 Cluster: Aldo/keto reductase; n=12; Alphaproteob...    46   7e-04
UniRef50_A6DNQ2 Cluster: YqkF; n=1; Lentisphaera araneosa HTCC21...    46   7e-04
UniRef50_A7E982 Cluster: Putative uncharacterized protein; n=1; ...    46   7e-04
UniRef50_UPI0000611A01 Cluster: PREDICTED: similar to MGC80525 p...    46   0.001
UniRef50_A7B5J6 Cluster: Putative uncharacterized protein; n=1; ...    46   0.001
UniRef50_A0K1H5 Cluster: Aldo/keto reductase; n=6; Actinomycetal...    46   0.001
UniRef50_Q27ST7 Cluster: Oxidoreductase; n=2; Eukaryota|Rep: Oxi...    46   0.001
UniRef50_A1CLD1 Cluster: Gamma-cysteine synthetase regulatory su...    46   0.001
UniRef50_Q7NH41 Cluster: Gll2696 protein; n=1; Gloeobacter viola...    45   0.001
UniRef50_Q6A7U3 Cluster: Putative oxidoreductase; n=1; Propionib...    45   0.001
UniRef50_A6VXU3 Cluster: Aldo/keto reductase; n=14; Proteobacter...    45   0.001
UniRef50_A5CYR4 Cluster: Predicted oxidoreductases; n=2; Clostri...    45   0.001
UniRef50_A0JZE6 Cluster: Aldo/keto reductase; n=1; Arthrobacter ...    45   0.001
UniRef50_UPI0000D9C1BD Cluster: PREDICTED: similar to aldo-keto ...    45   0.002
UniRef50_Q9X123 Cluster: Oxidoreductase, putative; n=4; Bacteria...    45   0.002
UniRef50_Q0BAM8 Cluster: Aldo/keto reductase; n=1; Burkholderia ...    45   0.002
UniRef50_A6FYX9 Cluster: Oxidoreductase; n=1; Plesiocystis pacif...    45   0.002
UniRef50_A4XIJ0 Cluster: Aldo/keto reductase; n=1; Caldicellulos...    45   0.002
UniRef50_A0LHW7 Cluster: Aldo/keto reductase precursor; n=1; Syn...    45   0.002
UniRef50_A0RYR0 Cluster: Oxidoreductase; n=2; cellular organisms...    45   0.002
UniRef50_Q38Z15 Cluster: Putative aldo/keto reductase; n=2; Bact...    44   0.002
UniRef50_Q45RB1 Cluster: Possible oxidoreductase; n=3; Actinomyc...    44   0.002
UniRef50_A7HER9 Cluster: Aldo/keto reductase; n=2; Anaeromyxobac...    44   0.002
UniRef50_A6E9U0 Cluster: Oxidoreductase; n=1; Pedobacter sp. BAL...    44   0.002
UniRef50_A6DVW2 Cluster: Oxidoreductase, aldo/keto reductase fam...    44   0.002
UniRef50_A0ZZJ3 Cluster: Oxidoreductase; n=2; Bifidobacterium ad...    44   0.002
UniRef50_A0Y7Y8 Cluster: Aldo/keto reductase; n=1; marine gamma ...    44   0.002
UniRef50_Q39151 Cluster: K+ channel protein; n=29; cellular orga...    44   0.002
UniRef50_Q5ASJ7 Cluster: Putative uncharacterized protein; n=1; ...    44   0.002
UniRef50_Q97UJ7 Cluster: Oxidoreductase; n=4; Archaea|Rep: Oxido...    44   0.002
UniRef50_O43488 Cluster: Aflatoxin B1 aldehyde reductase member ...    44   0.002
UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel...    44   0.003
UniRef50_Q3WFK9 Cluster: Aldo/keto reductase precursor; n=1; Fra...    44   0.003
UniRef50_A0K0K8 Cluster: Aryl-alcohol dehydrogenase (NADP(+)); n...    44   0.003
UniRef50_Q4WE75 Cluster: Aldehyde reductase (GliO), putative; n=...    44   0.003
UniRef50_Q2NFN7 Cluster: Predicted oxidoreductase; n=1; Methanos...    44   0.003
UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular organis...    44   0.004
UniRef50_Q88T82 Cluster: Oxidoreductase; n=18; Bacteria|Rep: Oxi...    44   0.004
UniRef50_Q6MHN8 Cluster: Potassium voltage-gated channel, shaker...    44   0.004
UniRef50_Q2J8X9 Cluster: Aldo/keto reductase; n=3; Frankia|Rep: ...    44   0.004
UniRef50_Q0SJ60 Cluster: Possible aldo/keto reductase; n=50; Bac...    44   0.004
UniRef50_A7GIW7 Cluster: Oxidoreductase, aldo/keto reductase fam...    44   0.004
UniRef50_A6EEC4 Cluster: Putative Norsolorinic acid reductase; n...    44   0.004
UniRef50_A0YC40 Cluster: Putative uncharacterized protein; n=1; ...    44   0.004
UniRef50_A0UVR1 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:...    44   0.004
UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa...    44   0.004
UniRef50_P76187 Cluster: Oxidoreductase ydhF; n=51; Gammaproteob...    44   0.004
UniRef50_Q4TC86 Cluster: Chromosome undetermined SCAF7044, whole...    43   0.005
UniRef50_Q0LSA5 Cluster: Aldo/keto reductase; n=2; Proteobacteri...    43   0.005
UniRef50_Q01U06 Cluster: Aldo/keto reductase; n=1; Solibacter us...    43   0.005
UniRef50_Q2NGB6 Cluster: Predicted oxidoreductase; n=1; Methanos...    43   0.005
UniRef50_Q0W0V6 Cluster: Predicted aldo/keto reductase; n=2; Eur...    43   0.005
UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose red...    43   0.006
UniRef50_Q9PCQ5 Cluster: Sugar-phosphate dehydrogenase; n=23; Ba...    43   0.006
UniRef50_Q09D95 Cluster: Ydhf chain A; n=1; Stigmatella aurantia...    43   0.006

>UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1;
           Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase -
           Trichoplusia ni (Cabbage looper)
          Length = 308

 Score =  230 bits (563), Expect = 2e-59
 Identities = 119/195 (61%), Positives = 143/195 (73%), Gaps = 3/195 (1%)
 Frame = +2

Query: 26  ITLTCLLNAAMAV--QAPCIQLNDGNTIPIVALGT-GRGTAKESDSIDEVRQAVYWAIEA 196
           + L  L+NA      +AP  QLNDGN IP +ALGT G G       I +VRQAV WAI+A
Sbjct: 8   VALWALVNAISGEPGKAPLKQLNDGNAIPSLALGTFGFG------DIPKVRQAVLWAIQA 61

Query: 197 GYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLK 376
           GYRHIDTAA+Y +EE+VG+GIA+AI  GLV REELFVTTKLWNDKH R QVVPAL+ESL 
Sbjct: 62  GYRHIDTAALYGNEEEVGKGIADAIQQGLVKREELFVTTKLWNDKHGRHQVVPALRESLT 121

Query: 377 KLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITR 556
           KLGL Y+DLYLIH P AT  +  P +ID L TW GM++A++LGLA+SIGVSNF+   + R
Sbjct: 122 KLGLSYVDLYLIHSPEATNENGDPVDIDVLNTWNGMEEAKKLGLAKSIGVSNFDTALLDR 181

Query: 557 LVSNSYIRPGXNQIE 601
           L++ S   P  NQIE
Sbjct: 182 LIAGSNTVPAVNQIE 196


>UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA;
           n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
           GA10458-PA - Nasonia vitripennis
          Length = 569

 Score =  180 bits (439), Expect = 2e-44
 Identities = 90/188 (47%), Positives = 127/188 (67%), Gaps = 11/188 (5%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P +  NDG  +P++ LGT            EV +AV +AIE GYRH+DTA  Y++E+++G
Sbjct: 4   PTVTFNDGYKMPMIGLGTFLSKP------GEVAEAVKYAIEVGYRHVDTAFFYENEKEIG 57

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430
             I E I +G + RE++FVTTKLW + H  D+VVPA ++SL+ LG DYIDL+L+H+P A 
Sbjct: 58  SAIREKINDGTIKREDIFVTTKLWCNSHKEDEVVPACKKSLENLGFDYIDLFLVHWPFAF 117

Query: 431 K------PDDSPDNI-----DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 577
           K      P D+   I     DYLETW+GM++ ++ GLARSIG+SNFN+ QI RL+S++ I
Sbjct: 118 KSGDALTPRDAAGKIEFSDTDYLETWKGMEECKRQGLARSIGLSNFNSEQIARLLSSAKI 177

Query: 578 RPGXNQIE 601
           +P  NQ+E
Sbjct: 178 KPVNNQVE 185



 Score =  148 bits (359), Expect = 9e-35
 Identities = 80/165 (48%), Positives = 108/165 (65%), Gaps = 9/165 (5%)
 Frame = +2

Query: 134 TAKESDSIDEV-RQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 310
           T +E  +I+++ +   Y  +   YRHIDTA +Y +E+ +G  I E I +G V RE+LFVT
Sbjct: 278 TPEEVSTIEKMGKHNKYLILLYRYRHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVT 337

Query: 311 TKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA-----TKPDDSP---DNIDYL 466
           TKL    H   +VVPA ++SL  LGLDYIDLYLIH+PI       K         + DYL
Sbjct: 338 TKLSYYAHKESEVVPACKQSLNDLGLDYIDLYLIHWPIRRYFRHNKNASGKLLLSDTDYL 397

Query: 467 ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
           ETW+GM++ ++ GLARSIGVSNFN+ QITRL+  + I+P  NQ+E
Sbjct: 398 ETWKGMEECKRQGLARSIGVSNFNSEQITRLLEAAKIKPVNNQVE 442


>UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto
           reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to aldo-keto reductase - Nasonia vitripennis
          Length = 321

 Score =  179 bits (436), Expect = 4e-44
 Identities = 91/186 (48%), Positives = 126/186 (67%), Gaps = 11/186 (5%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           I L+DGN +P++ LGT +G     +  DEV  AV  AI+AGYRH D A+ Y +E ++G+ 
Sbjct: 8   ITLSDGNKVPVLGLGTWQG----GNDPDEVENAVKLAIDAGYRHFDCASFYGNEAEIGKA 63

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP----- 421
           I E I  G+V RE+LFV TK+WND+  ++ VV A + SLKKLGL YIDLYL+H+P     
Sbjct: 64  IQEKIDQGVVKREDLFVVTKVWNDERKQELVVAACKRSLKKLGLGYIDLYLVHWPFSYPI 123

Query: 422 ------IATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRP 583
                 + T    + D +DY+ETW+GM++  +LGL RSIGVSNFN+ Q+TRL+ ++ I+P
Sbjct: 124 LYQYIVLPTYNAVTLDEVDYIETWRGMEECIKLGLTRSIGVSNFNSQQLTRLLESASIKP 183

Query: 584 GXNQIE 601
             NQIE
Sbjct: 184 VMNQIE 189


>UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase
           precursor; n=1; Spodoptera littoralis|Rep:
           3-dehydroecdysone 3beta-reductase precursor - Spodoptera
           littoralis (Egyptian cotton leafworm)
          Length = 345

 Score =  171 bits (415), Expect = 1e-41
 Identities = 84/196 (42%), Positives = 122/196 (62%), Gaps = 3/196 (1%)
 Frame = +2

Query: 23  IITLTCLLNAAMAVQAPCIQLNDGNTIPIVALGTGRGTAKES--DSID-EVRQAVYWAIE 193
           I+ L C    +  +  P +++ +   +P +ALGT  G  K     S D ++R  V  AI+
Sbjct: 7   ILLLACCGAMSATIDVPMLKMLNDREMPAIALGTYLGFDKGGAVTSKDKQLRNVVMQAID 66

Query: 194 AGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESL 373
            GYRH DTAA+Y  E +VG+ I   I  G++ RE++F+TTKLWN  H R+QV  A++E+L
Sbjct: 67  LGYRHFDTAAIYNTEAEVGEAIRMKIDEGVIKREDVFLTTKLWNTHHKREQVAVAMKETL 126

Query: 374 KKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQIT 553
            K GLDY+DL+L+H+PIA   D S  N DYLETW+  ++  +LG  +SIG+SNFN  Q+ 
Sbjct: 127 NKTGLDYVDLFLMHWPIALNEDYSHSNTDYLETWRATEEMVKLGYTKSIGLSNFNKLQVA 186

Query: 554 RLVSNSYIRPGXNQIE 601
            ++    I+P   QIE
Sbjct: 187 TVLQECTIKPVALQIE 202


>UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p -
           Drosophila melanogaster (Fruit fly)
          Length = 311

 Score =  162 bits (393), Expect = 7e-39
 Identities = 89/186 (47%), Positives = 120/186 (64%), Gaps = 8/186 (4%)
 Frame = +2

Query: 68  APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247
           AP I+LN+G  +P + LGT +    ESD+    R A    ++ GYRH+DTA VY++E +V
Sbjct: 5   APTIRLNNGREMPTLGLGTWKSF--ESDAYHSTRHA----LDVGYRHLDTAFVYENEAEV 58

Query: 248 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427
           GQ I+E IA G+VTREE+FVTTKL    H    V  A + SL  LGL+Y+DLYL+H P+ 
Sbjct: 59  GQAISEKIAEGVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMPVG 118

Query: 428 TK-PDDSP-------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRP 583
            K  +DS         ++DYL+TW+ M+    LGL RSIG+SNFNA Q  R+++N  IRP
Sbjct: 119 QKFHNDSNVHGTLELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVLANCRIRP 178

Query: 584 GXNQIE 601
             NQ+E
Sbjct: 179 VVNQVE 184


>UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13;
           n=11; Theria|Rep: Aldo-keto reductase family 1 member
           C13 - Mus musculus (Mouse)
          Length = 323

 Score =  155 bits (377), Expect = 6e-37
 Identities = 81/195 (41%), Positives = 121/195 (62%), Gaps = 13/195 (6%)
 Frame = +2

Query: 56  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235
           M+ +  C++LNDG+ IP  ALG G    KE      + +A   A++ GYRH+DTA  YQ 
Sbjct: 1   MSSKQHCVKLNDGHLIP--ALGFGTYKPKEVPKSKSL-EAACLALDVGYRHVDTAYAYQV 57

Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415
           EE++GQ I   I  G+V RE+LF+TTKLW      + V PAL++SLKKL LDY+DLY++H
Sbjct: 58  EEEIGQAIQSKIKAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMH 117

Query: 416 FPIATKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 562
           +P+  K  D+            D +D+ +TW+ +++ +  GL +SIGVSNFN  Q+ R++
Sbjct: 118 YPVPMKSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERIL 177

Query: 563 SNSYI--RPGXNQIE 601
           +   +  +P  NQ+E
Sbjct: 178 NKPGLKYKPVCNQVE 192


>UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep:
           Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea)
          Length = 321

 Score =  155 bits (375), Expect = 1e-36
 Identities = 78/192 (40%), Positives = 126/192 (65%), Gaps = 10/192 (5%)
 Frame = +2

Query: 56  MAVQAPCIQLNDGNT-IPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQ 232
           MA   P + L+ G   +P++ LGT      + ++   VR+AV  A++ GYRH DTAA+Y 
Sbjct: 1   MAFTIPEVPLSSGGRKMPVLGLGTAADPPVDPET---VRKAVTEALKLGYRHFDTAALYN 57

Query: 233 DEEQVGQGIAEAIANGLV-TREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYL 409
            E+ +G  IAEA+  GL+ +R+ELF+T+KLW     R+ V PALQ++LK L L+YID+YL
Sbjct: 58  SEQPLGDAIAEALGEGLIKSRDELFITSKLWCSDAHRENVEPALQKTLKNLKLEYIDMYL 117

Query: 410 IHFPIATKPDD------SPD--NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVS 565
           IH+P+++KP +        D   +DY   W+ M++ ++LGL ++IGVSNF+  +++ +++
Sbjct: 118 IHWPVSSKPGNYEYPIKKEDFLQMDYKSVWEAMEECQKLGLTKAIGVSNFSCKKLSDVLA 177

Query: 566 NSYIRPGXNQIE 601
           N+ + P  NQ+E
Sbjct: 178 NAKVPPAVNQVE 189


>UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein;
           n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9
           protein - Oryza sativa (Rice)
          Length = 337

 Score =  153 bits (370), Expect = 4e-36
 Identities = 86/198 (43%), Positives = 121/198 (61%), Gaps = 14/198 (7%)
 Frame = +2

Query: 50  AAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVY 229
           AA A   PC+ LN G+ +P++  GTG  T        ++   +  A+  GYRH+DTAAVY
Sbjct: 14  AAAATAVPCVTLNSGHAMPVLGFGTGSSTPPA-----DLAATIAHAVRLGYRHLDTAAVY 68

Query: 230 QDEEQVGQGIAEAIANGLV-TREELFVTTKL-WNDKHARDQVVPALQESLKKLGLDYIDL 403
             E  VG  +AEA+  G V +R ELFVTTKL   D H   +VV AL+ESL +LGLDY+DL
Sbjct: 69  GTEGAVGAAVAEAVRCGAVASRGELFVTTKLSMADAHP-PRVVAALRESLSRLGLDYVDL 127

Query: 404 YLIHFPIATKPDDSPDNI------------DYLETWQGMQDARQLGLARSIGVSNFNATQ 547
           +LIH+P+A    D+   +            D    W+GM++  +LGLARSIGVSNF+A +
Sbjct: 128 FLIHWPVAIGKKDAAGELTWDDLSRGLVPFDMEGVWRGMEECHRLGLARSIGVSNFSAAK 187

Query: 548 ITRLVSNSYIRPGXNQIE 601
           ++RL++ + + P  NQ+E
Sbjct: 188 MSRLLALAAVPPAVNQVE 205


>UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep:
           GA19341-PA - Drosophila pseudoobscura (Fruit fly)
          Length = 315

 Score =  153 bits (370), Expect = 4e-36
 Identities = 86/192 (44%), Positives = 115/192 (59%), Gaps = 12/192 (6%)
 Frame = +2

Query: 62  VQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEE 241
           +  P   L+ G  +P+V LGT R         + V QAV  AI+ GYRH D A +Y +E 
Sbjct: 1   MSTPSFLLSSGRNMPMVGLGTWRSPP------EVVAQAVKDAIDIGYRHFDCAHIYGNEL 54

Query: 242 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 421
            VG  I E I  GLVTR+ELF+T+KLWN  H  + V  A + SL+ LG+DY+DLYL+H+P
Sbjct: 55  HVGVAIREKIQEGLVTRDELFITSKLWNTFHKPELVRAACETSLRNLGIDYLDLYLMHWP 114

Query: 422 IATKPDDS-----PD-------NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVS 565
           +A K  D+     PD       +IDYL+TW+ M+D    GL  +IGVSNFN  QI RL+ 
Sbjct: 115 MAYKSGDNLYPTCPDTGKAVFEDIDYLDTWKAMEDLVDSGLVNAIGVSNFNEKQINRLLC 174

Query: 566 NSYIRPGXNQIE 601
            + ++P   QIE
Sbjct: 175 LAKLKPVMLQIE 186


>UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9;
           Endopterygota|Rep: ENSANGP00000031808 - Anopheles
           gambiae str. PEST
          Length = 316

 Score =  151 bits (367), Expect = 9e-36
 Identities = 85/183 (46%), Positives = 112/183 (61%), Gaps = 12/183 (6%)
 Frame = +2

Query: 89  DGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEA 268
           +GN+IP+  LGT            +V QAV  AI+ GYRHID A VYQ+E +VG+GIA  
Sbjct: 13  NGNSIPMFGLGTWNSPP------GQVAQAVKDAIDVGYRHIDCAHVYQNEHEVGEGIAAK 66

Query: 269 IANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK----- 433
           IA G+V RE+LFVT+KLWN  H  D V  A + +L+ L LDY+DLYLIH+P+  +     
Sbjct: 67  IAEGVVKREDLFVTSKLWNTFHRPDLVEGACKTTLQNLKLDYLDLYLIHWPVGYQEGTEL 126

Query: 434 ----PDDSP---DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXN 592
               PD       + DY++TW  M+     GL R+IGVSNFNA Q+ R++  + I P  N
Sbjct: 127 FPMGPDGKTFLFSDADYVDTWPEMEKLVDAGLVRNIGVSNFNAKQVQRVLDVARIPPATN 186

Query: 593 QIE 601
           QIE
Sbjct: 187 QIE 189


>UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep:
           Aldo-keto reductase - Aedes aegypti (Yellowfever
           mosquito)
          Length = 324

 Score =  151 bits (367), Expect = 9e-36
 Identities = 83/192 (43%), Positives = 115/192 (59%), Gaps = 15/192 (7%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P ++LN+G  +P + LGT           DE  +AV  AI+ G+RHIDTA  Y++E+ VG
Sbjct: 7   PTVKLNNGLEMPAIGLGTSMSKG------DECCKAVMTAIDEGFRHIDTAYNYRNEDVVG 60

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430
           + I   I  G+VTREELFVTTKLWN  H  D V  A  +SL+ LGLDY+DL+LIH P   
Sbjct: 61  RAIRAKIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSLEHLGLDYVDLFLIHMPFGY 120

Query: 431 K----------PDDSPDNI-----DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVS 565
           +          P D   N+     DY++TW+ M+   + G   SIGVSNFN+ Q+ R+++
Sbjct: 121 EFNGWDPEKRTPLDDNGNVLCSDDDYVDTWKAMEKLLESGRVHSIGVSNFNSEQLERILA 180

Query: 566 NSYIRPGXNQIE 601
           N  ++P  NQ+E
Sbjct: 181 NCRVKPVTNQVE 192


>UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18;
           n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member
           C18 - Mus musculus (Mouse)
          Length = 323

 Score =  151 bits (366), Expect = 1e-35
 Identities = 77/188 (40%), Positives = 118/188 (62%), Gaps = 13/188 (6%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           I+LNDG++IP++  GT    A E     +  ++   AI+ G+ HID + +YQ+EE++GQ 
Sbjct: 8   IELNDGHSIPVLGFGT---YATEEHLKKKSMESTKIAIDVGFCHIDCSHLYQNEEEIGQA 64

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
           I   I +G V RE++F T+KLW+  H  + V P+L+ SL+KL LDY+DLYLIHFP++ KP
Sbjct: 65  ILSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKP 124

Query: 437 DDS--P---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 577
            +   P         D +D  +TW+ M+  +  GLA+SIGVSNFN  Q+  +++   +  
Sbjct: 125 GNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184

Query: 578 RPGXNQIE 601
           +P  NQ+E
Sbjct: 185 KPVCNQVE 192


>UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2;
           Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus
           sp. (strain CC9311)
          Length = 336

 Score =  151 bits (365), Expect = 2e-35
 Identities = 75/183 (40%), Positives = 120/183 (65%), Gaps = 10/183 (5%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
           L++G+ +P++ LGTG+  +++      V ++V  AI+ GYRHID A++Y +EE+VG  I 
Sbjct: 24  LSNGDRMPLLGLGTGKSESRQ------VYKSVREAIKIGYRHIDCASIYGNEEEVGDAIR 77

Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 436
           +AI N  +TR EL++T+KLW++ H ++ V  AL +SL+ LG+DY++LYLIH+P+  +P  
Sbjct: 78  DAIQNHEITRSELWITSKLWSNCHGKNHVEAALSQSLQNLGVDYLNLYLIHWPVGIRPEK 137

Query: 437 ------DD--SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXN 592
                 DD  +P+     ETW+ M+  R  GL + IGVSNF   ++ +LVS+   +P  N
Sbjct: 138 TFAESVDDLLTPEESPISETWEAMESTRDKGLTKHIGVSNFTVKKLQQLVSHCKQKPEVN 197

Query: 593 QIE 601
           Q+E
Sbjct: 198 QVE 200


>UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 323

 Score =  150 bits (364), Expect = 2e-35
 Identities = 84/193 (43%), Positives = 115/193 (59%), Gaps = 11/193 (5%)
 Frame = +2

Query: 56  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235
           MA++    +LN G +IP +ALGT +       S +EV  AV  AIE GYRHID A +Y +
Sbjct: 1   MAMKQIFCKLNTGASIPAMALGTWQS------SKEEVGNAVRLAIELGYRHIDCAEIYGN 54

Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415
           E ++G+ ++E +  G V REELFVT+KLW D H  D V+PA Q +LK L LDY+DLYLIH
Sbjct: 55  EGEIGEALSEVLTEGKVKREELFVTSKLWCDSHHPDDVLPACQATLKNLQLDYLDLYLIH 114

Query: 416 FPIATK-----PDDSPDNI------DYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 562
            P+A K     P    + I          TWQ M+     GL ++IGVSNF+  ++ +L+
Sbjct: 115 IPVAFKKGVRLPHSIAEGIIGYTPEGVQNTWQAMEGLVAKGLCKAIGVSNFSVKRLNKLL 174

Query: 563 SNSYIRPGXNQIE 601
             + I P  NQ+E
Sbjct: 175 ETASIVPACNQVE 187


>UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 320

 Score =  147 bits (355), Expect = 3e-34
 Identities = 76/183 (41%), Positives = 116/183 (63%), Gaps = 1/183 (0%)
 Frame = +2

Query: 56  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235
           M+ + P   L++G  +P + LGT + T +E  ++  +R AV     AGYRHIDTA +YQ+
Sbjct: 1   MSSKVPIFTLSNGVLMPSIGLGTWQMTGEEGKTV--IRNAVL----AGYRHIDTATLYQN 54

Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415
           E Q+G  +AE  A G++ RE++F+TTK +  + A D V  AL+ SLK+L LDY+DLYL H
Sbjct: 55  EHQIGDALAELFAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAH 114

Query: 416 FPIATKPDDS-PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXN 592
            P +TK D S   ++   + W+G +    LGL ++IGVSNFN +QI R+++   +    +
Sbjct: 115 IPASTKDDGSFRSDVKVEDIWRGFEKVYGLGLTKAIGVSNFNESQIVRIMNIQKVPIHAS 174

Query: 593 QIE 601
           Q+E
Sbjct: 175 QLE 177


>UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase
           family; n=2; Entamoeba histolytica HM-1:IMSS|Rep:
           oxidoreductase, aldo/keto reductase family - Entamoeba
           histolytica HM-1:IMSS
          Length = 305

 Score =  146 bits (353), Expect = 5e-34
 Identities = 85/177 (48%), Positives = 110/177 (62%), Gaps = 4/177 (2%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
           LN+G  IP + LGT            EV +AV  AI+ GYRHID A  Y +E++VG GI 
Sbjct: 7   LNNGYKIPKLGLGTWMSAN------GEVGKAVEIAIKNGYRHIDCAKAYGNEKEVGDGIK 60

Query: 263 EAIANGLVTREELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP- 436
            AIA G V REELFVTTKLW+ DKH  D V PA  ESLKKL L+Y+DLY+IH P+     
Sbjct: 61  SAIAKGYVKREELFVTTKLWSTDKHKED-VRPACLESLKKLQLEYLDLYIIHIPLTADKK 119

Query: 437 --DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
             + + + I   ETW+ M+   + GL +SIGVSNFN  ++  L++ + I+P  NQ E
Sbjct: 120 TGEFTEEIIPIEETWREMEKLVEEGLVKSIGVSNFNIKKLEELLAIAKIQPAVNQFE 176


>UniRef50_Q41399 Cluster: Chalcone reductase; n=4;
           eudicotyledons|Rep: Chalcone reductase - Sesbania
           rostrata
          Length = 322

 Score =  146 bits (353), Expect = 5e-34
 Identities = 74/188 (39%), Positives = 125/188 (66%), Gaps = 11/188 (5%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYW-AIEAGYRHIDTAAVYQDEEQV 247
           P + LN G+ +P++    G GT+ ES   ++V  +++  AI+ GYRH D+A+VY  EE +
Sbjct: 7   PEVLLNSGHKMPVI----GMGTSVESRPSNDVLASIFVDAIQVGYRHFDSASVYGTEEAI 62

Query: 248 GQGIAEAIANGLV-TREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424
           G  +++AI  GL+ +R+E+F+T+K WN     D +VPAL+ +LKKLG++Y+DLYLIH+P+
Sbjct: 63  GMAVSKAIEQGLIKSRDEVFITSKPWNTDAHHDLIVPALKTTLKKLGMEYVDLYLIHWPV 122

Query: 425 ATKPD-DSP-----DNI---DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 577
             + D ++P     +++   D   TW+ M++  +LGLA+SIG+ N+   ++T+L+  + I
Sbjct: 123 RLRHDLENPVIFSKEDLLPFDIEGTWKAMEECYRLGLAKSIGICNYGTKKLTKLLEIATI 182

Query: 578 RPGXNQIE 601
            P  NQ+E
Sbjct: 183 PPAVNQVE 190


>UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA -
           Drosophila melanogaster (Fruit fly)
          Length = 322

 Score =  145 bits (352), Expect = 6e-34
 Identities = 79/193 (40%), Positives = 119/193 (61%), Gaps = 13/193 (6%)
 Frame = +2

Query: 62  VQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEE 241
           +  P   L++G  +P++ LGT R         + V QAV  AI+ GYRH D A +Y +E 
Sbjct: 1   MSTPNFLLSNGKNMPMLGLGTWRSPP------EVVTQAVKDAIDIGYRHFDCAHIYGNEA 54

Query: 242 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 421
           QVG  + E +  G+VTR+ELF+T+KLWN  H  D V PA + S++ LG+ Y++LYL+H+P
Sbjct: 55  QVGAALREKMDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWP 114

Query: 422 IATK----------PDDSP---DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 562
           +A K          PD +    ++IDY++TW+ M++    GL ++IGVSNFN  Q+ RL+
Sbjct: 115 MAYKSGSDNLYPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLL 174

Query: 563 SNSYIRPGXNQIE 601
           S + ++P   QIE
Sbjct: 175 SVAKLKPVVLQIE 187


>UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44;
           Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo
           sapiens (Human)
          Length = 325

 Score =  145 bits (351), Expect = 8e-34
 Identities = 75/190 (39%), Positives = 117/190 (61%), Gaps = 12/190 (6%)
 Frame = +2

Query: 68  APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247
           A C+ L+ G  +P++ LGT +          +V+ AV +A+  GYRHID AA+Y +E ++
Sbjct: 3   ASCVLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEI 56

Query: 248 GQGIAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424
           G+ + E +  G  V REELFVT+KLWN KH  + V PAL+++L  L L+Y+DLYL+H+P 
Sbjct: 57  GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116

Query: 425 ATKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 571
           A +  D+P           D+  Y ETW+ ++     GL +++G+SNFN+ QI  ++S +
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176

Query: 572 YIRPGXNQIE 601
            +RP   Q+E
Sbjct: 177 SVRPAVLQVE 186


>UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep:
           Aldehyde reductase - gamma proteobacterium HTCC2207
          Length = 330

 Score =  144 bits (350), Expect = 1e-33
 Identities = 85/201 (42%), Positives = 116/201 (57%), Gaps = 20/201 (9%)
 Frame = +2

Query: 59  AVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDE 238
           A+Q P ++++   ++P V LG  + T       D   QAVY AI+ GYRH+D+AA Y +E
Sbjct: 4   AIQVPGVKVSS-KSMPAVGLGLWKITQ------DSAAQAVYEAIKVGYRHLDSAADYGNE 56

Query: 239 EQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 418
           +QVG+GIA AIA GL +REEL++TTKLWN  H  + V  A + S+  LGLDYIDLYL+HF
Sbjct: 57  QQVGEGIARAIAEGLCSREELWITTKLWNTYHRAEHVEAACRRSMDDLGLDYIDLYLVHF 116

Query: 419 PIATK--------------------PDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFN 538
           PIA +                    P    D +   ETW  M+   + GL R IGV N++
Sbjct: 117 PIALRYVDFNDRYPAEWIFDHSAEDPAMELDQVPLSETWGAMEQLVESGLVRQIGVCNYS 176

Query: 539 ATQITRLVSNSYIRPGXNQIE 601
           A  +  L+S + I+P   QIE
Sbjct: 177 AVLLHDLMSYARIKPAMLQIE 197


>UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5;
           Bacteroidetes|Rep: Aldehyde reductase - Croceibacter
           atlanticus HTCC2559
          Length = 316

 Score =  143 bits (347), Expect = 3e-33
 Identities = 77/186 (41%), Positives = 120/186 (64%), Gaps = 11/186 (5%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           ++  DG++IP + LGT +     SD  ++V++AV  A+E GY+HID AA Y +E+ VG+ 
Sbjct: 4   LKFRDGDSIPSIGLGTWK-----SDP-EDVKKAVKIALENGYKHIDCAAAYDNEDAVGEA 57

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
             E+  +G V RE++FVT+KLWN+ H ++ V+PAL+++LK L LDY+DLYL+H+P+A KP
Sbjct: 58  FKESFESGNVKREDIFVTSKLWNNAHKKEDVIPALKKTLKDLNLDYLDLYLMHWPVAFKP 117

Query: 437 --DDSPD-NIDYL--------ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRP 583
             +  P+ + DYL        ET   M +A++ GL + +GVSNF+  ++  L       P
Sbjct: 118 SVNGFPEKDEDYLSLEEAPLHETLNAMIEAKKQGLIKHVGVSNFSKEKLESLKGKVEEMP 177

Query: 584 GXNQIE 601
             NQ+E
Sbjct: 178 EMNQVE 183


>UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep:
           GCY protein - Lodderomyces elongisporus (Yeast)
           (Saccharomyces elongisporus)
          Length = 295

 Score =  143 bits (347), Expect = 3e-33
 Identities = 80/191 (41%), Positives = 124/191 (64%), Gaps = 5/191 (2%)
 Frame = +2

Query: 44  LNAAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAA 223
           +++ +++      LN+G  IP + LGT       +D  D   +A   A++ GY+HIDTAA
Sbjct: 1   MSSQLSINTKTYTLNNGLKIPAIGLGTWL-----ADEEDAAYKATLTALKNGYKHIDTAA 55

Query: 224 VYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDL 403
            Y +E+QVG+    AIA+  V+R+E+FVTTKLWND+H   +   AL ESLKKLGL+Y+DL
Sbjct: 56  AYGNEDQVGR----AIADSGVSRDEIFVTTKLWNDQHKDPE--GALDESLKKLGLEYVDL 109

Query: 404 YLIHFPIATKP-DDSP-DNIDYLETWQGMQDARQLG-LARSIGVSNFNATQITRLVSNSY 574
           YLIH+P++  P  + P D+ D+++TW+ +Q   + G   ++IGVSNFN  ++ +L+++  
Sbjct: 110 YLIHWPLSVDPKTEKPYDDYDFVDTWRNLQKIYKEGKKVKAIGVSNFNKKKLDKLLNSEG 169

Query: 575 IR--PGXNQIE 601
           +   P  NQIE
Sbjct: 170 VNVVPVINQIE 180


>UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;
           n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
           reductase A - Corynebacterium sp. (strain ATCC 31090)
          Length = 278

 Score =  143 bits (347), Expect = 3e-33
 Identities = 82/177 (46%), Positives = 111/177 (62%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P I LNDGN+IP   LG G      +D+    ++AV  A+E GYRHIDTAA+Y +EE VG
Sbjct: 4   PSIVLNDGNSIP--QLGYGVFKVPPADT----QRAVEEALEVGYRHIDTAAIYGNEEGVG 57

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430
             IA   A+G + R++LF+TTKLWND+H  D+   A+ ESL KL LD +DLYL+H+P   
Sbjct: 58  AAIA---ASG-IARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWP--- 110

Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
               +P   +Y+  W+ M + R  GL RSIGVSN     + R+V+ + + P  NQIE
Sbjct: 111 ----TPAADNYVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVPAVNQIE 163


>UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=1; Lactobacillus brevis ATCC
           367|Rep: Aldo/keto reductase of diketogulonate reductase
           family - Lactobacillus brevis (strain ATCC 367 / JCM
           1170)
          Length = 293

 Score =  142 bits (345), Expect = 4e-33
 Identities = 74/177 (41%), Positives = 114/177 (64%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P + +N+G+ IP + LG       + D+ ++ + A+ WA+ AGYRHIDTAA Y +E+ VG
Sbjct: 12  PDLPMNNGHQIPQLGLGVF-----QVDNAEDTKNAIKWALAAGYRHIDTAAYYGNEQWVG 66

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430
           + I E+     V R+++FVT+KLWN     D+   A QE+L KLGLDY+DLYLIH+P   
Sbjct: 67  EAIRESD----VPRDQIFVTSKLWNSVRGYDETQAAFQETLDKLGLDYLDLYLIHWP--- 119

Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
               +P    YL++W+ M+D  + G  ++IGVSNFN TQ+  ++++  ++P  +QIE
Sbjct: 120 ----AP---GYLDSWRAMEDLYKAGKIKNIGVSNFNQTQMADILAHGTVKPVVDQIE 169


>UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2;
           Oryza sativa (japonica cultivar-group)|Rep: Putative
           uncharacterized protein - Oryza sativa subsp. japonica
           (Rice)
          Length = 288

 Score =  142 bits (344), Expect = 6e-33
 Identities = 74/188 (39%), Positives = 117/188 (62%), Gaps = 11/188 (5%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P   L+ G  +P V +GT       +D    V+  V  AIEAGYRH DTAAVYQ E  +G
Sbjct: 2   PEAALSSGKPMPRVGMGTASFPLGATDP-STVKDVVLRAIEAGYRHFDTAAVYQTEAILG 60

Query: 251 QGIAEAIANGLV-TREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427
             +AEA+  GLV +R+EL++T+KLW        V+P+L+ +L+K+ ++Y+DLYLIHFP++
Sbjct: 61  DAVAEAVRAGLVASRDELYITSKLWVAHAHPGHVLPSLRRALRKMQMEYLDLYLIHFPVS 120

Query: 428 TKPDDSPDNIDYLE----------TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 577
            +  + P+++ Y +           W+ M++ ++LGL ++IGVSNF+  ++  L+S + I
Sbjct: 121 MRLAEDPESMTYSKDDLVMMDMEGVWKEMEECQRLGLTKAIGVSNFSCKKLETLLSFATI 180

Query: 578 RPGXNQIE 601
            P  NQ+E
Sbjct: 181 SPAANQVE 188


>UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase
           1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent
           oxidoreductase 1 - Oryza sativa subsp. japonica (Rice)
          Length = 321

 Score =  142 bits (344), Expect = 6e-33
 Identities = 77/179 (43%), Positives = 117/179 (65%), Gaps = 11/179 (6%)
 Frame = +2

Query: 98  TIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIAN 277
           T+P V +GT    A    S ++   A+  AIE GYRH DTA +Y  E  VG+ +AEA+  
Sbjct: 15  TMPRVGMGTA---AFPFTSSEDTTAAMLRAIELGYRHFDTARIYATEGCVGEAVAEAVRR 71

Query: 278 GLV-TREELFVTTKLW-NDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD--DS 445
           GL+ +R ++FVT+K+W +D HA  +VVPA +E+L+ LG+DY+DL L+H+P++  P   D 
Sbjct: 72  GLIASRADVFVTSKIWCSDLHA-GRVVPAARETLRNLGMDYVDLLLVHWPVSLTPGNYDF 130

Query: 446 P-------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
           P        + D    W+GM++  +LGLAR+IGVSNF+A ++ +L+S + +RP  NQ+E
Sbjct: 131 PFPKEVILPSFDMEGVWRGMEECHRLGLARAIGVSNFSAKKLEQLLSLAAVRPAVNQVE 189


>UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:
           Aldehyde reductase - Salinibacter ruber (strain DSM
           13855)
          Length = 321

 Score =  141 bits (342), Expect = 1e-32
 Identities = 72/185 (38%), Positives = 114/185 (61%), Gaps = 10/185 (5%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           I   +G+ +P++ LGT +          EV +AV  A+EAGYRH+D A +Y++E +VG  
Sbjct: 4   ISFENGDEMPMIGLGTWKSPP------GEVYEAVTTALEAGYRHVDCAPIYKNETEVGAA 57

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK- 433
           ++++   G + R++++VT+KLWN+ H  D V PAL+++L  L LD +DLYLIH+P+A + 
Sbjct: 58  LSDSFDAGGIRRDDVWVTSKLWNNAHHPDDVRPALEQTLSDLRLDALDLYLIHWPVALQP 117

Query: 434 -------PDD--SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPG 586
                  PDD  SP+ +   ETW  M+  ++ GL R IGVSNF+   +  ++    +RP 
Sbjct: 118 EVDFPESPDDFVSPEAVPLTETWAAMEALKKDGLVRHIGVSNFSVPNLQMILDAGEVRPE 177

Query: 587 XNQIE 601
            NQ+E
Sbjct: 178 MNQVE 182


>UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core
           eudicotyledons|Rep: Aldose reductase-like protein -
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 316

 Score =  141 bits (341), Expect = 1e-32
 Identities = 75/183 (40%), Positives = 110/183 (60%), Gaps = 9/183 (4%)
 Frame = +2

Query: 80  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259
           +L  G TIP++ +GT         +I  V QA    I+ GYRH DTA +Y  EE +G  +
Sbjct: 7   RLRCGETIPLLGMGTYCPQKDRESTISAVHQA----IKIGYRHFDTAKIYGSEEALGTAL 62

Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP- 436
            +AI+ G V R++LFVT+KLW+  H     + AL ++LK +GLDY+D YL+H+PI  KP 
Sbjct: 63  GQAISYGTVQRDDLFVTSKLWSSDH--HDPISALIQTLKTMGLDYLDNYLVHWPIKLKPG 120

Query: 437 --------DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXN 592
                   D+   ++   ETWQGM+   ++GL RSIGVSNF++ +I  L+  + + P  N
Sbjct: 121 VSEPIPKEDEFEKDLGIEETWQGMERCLEMGLCRSIGVSNFSSKKIFDLLDFASVSPSVN 180

Query: 593 QIE 601
           Q+E
Sbjct: 181 QVE 183


>UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus
           tropicalis|Rep: LOC594893 protein - Xenopus tropicalis
           (Western clawed frog) (Silurana tropicalis)
          Length = 345

 Score =  140 bits (340), Expect = 2e-32
 Identities = 84/210 (40%), Positives = 115/210 (54%), Gaps = 31/210 (14%)
 Frame = +2

Query: 65  QAPCIQLNDGNTIPIVALGT------------------GRGTAKESDSIDEVRQAVYWAI 190
           Q   IQL+DG  +P+VA GT                  G     E   ID+VR A   A+
Sbjct: 5   QGASIQLHDGRWMPVVAFGTFYPFTFPGDSQANPGHCAGTKHGTEKSFIDDVRVATKMAL 64

Query: 191 EAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQES 370
           + GYRH+D A +Y  E  VGQ   E  A+G + RE+LF T+KLWN  H    V PAL+++
Sbjct: 65  DLGYRHVDGAFLYSSETGVGQAFREKFADGTLKREDLFYTSKLWNTFHQPHLVRPALEKT 124

Query: 371 LKKLGLDYIDLYLIHFPIATKPDDS--P---------DNIDYLETWQGMQDARQLGLARS 517
           L  L +DY+DLYLIH P++ KP +   P         D  D L+TWQ +++ R  GL +S
Sbjct: 125 LSFLQMDYVDLYLIHMPMSFKPAEELFPKNEDGTCAFDQPDLLQTWQALEECRDAGLVKS 184

Query: 518 IGVSNFNATQITRLVSNSYI--RPGXNQIE 601
           IGVSNFN  Q+  +++   +  +P  NQIE
Sbjct: 185 IGVSNFNRRQLEMILNKPGLKYKPVCNQIE 214


>UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase;
           n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid
           dehydrogenase - Xenopus tropicalis (Western clawed frog)
           (Silurana tropicalis)
          Length = 324

 Score =  140 bits (340), Expect = 2e-32
 Identities = 78/188 (41%), Positives = 114/188 (60%), Gaps = 13/188 (6%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           ++LNDG+ +P++  GT     K   S+ E    V  AI+ GYRHID A +Y +EE+VG+ 
Sbjct: 9   VELNDGHKMPVIGFGT-YAPPKFPKSLAEEGTKV--AIDVGYRHIDCAFLYGNEEEVGRA 65

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
           I   IA+G V RE++F T KLW+  H  ++V PAL++SLK L LDY+DL++IH P+  KP
Sbjct: 66  IRAKIADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPMEFKP 125

Query: 437 DDS--P---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 577
            D   P          N D  +TW+ ++  +  GL RSIGVSNFN  Q+  +++   +  
Sbjct: 126 GDDLFPADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIGVSNFNHKQLELILNMPGLKY 185

Query: 578 RPGXNQIE 601
           +P  NQ+E
Sbjct: 186 KPVCNQVE 193


>UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep:
           Oxidoreductase - Lactobacillus plantarum
          Length = 286

 Score =  139 bits (336), Expect = 5e-32
 Identities = 80/172 (46%), Positives = 104/172 (60%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
           LN+G  IPIV  GT + T     + D V  A    ++AGYRHIDTAA Y +EE VG+   
Sbjct: 13  LNNGTKIPIVGFGTWQ-TPDGQVAYDSVLAA----LKAGYRHIDTAAAYGNEESVGK--- 64

Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 442
            AIA+  V RE+LFVTTKLWN  H  D    AL  SL KLGLDY+DLYLIH+P      D
Sbjct: 65  -AIADSGVAREDLFVTTKLWNADHGYDAAKKALDTSLAKLGLDYVDLYLIHWPNPAAMRD 123

Query: 443 SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598
           + + ++  +TW+ M++A     AR+IGVSNF    +  L+  + + P  NQI
Sbjct: 124 NWEQLN-ADTWRAMEEAYTARKARAIGVSNFRPKHLDALLKTAKVVPAVNQI 174


>UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase
           2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent
           oxidoreductase 2 - Oryza sativa subsp. japonica (Rice)
          Length = 322

 Score =  139 bits (336), Expect = 5e-32
 Identities = 76/179 (42%), Positives = 113/179 (63%), Gaps = 11/179 (6%)
 Frame = +2

Query: 98  TIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIAN 277
           T+P + +GT    A    S +E   A+  AIE GYRH DTA +Y  E  V + +AEA+  
Sbjct: 17  TMPRIGMGTA---AFPFTSSEETTAALLRAIELGYRHFDTARLYATEGCVSEAVAEAVRR 73

Query: 278 GLV-TREELFVTTKLW-NDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP----- 436
           GLV +R ++FVT+KLW +D HA  +VVPA +E+L+ LG+DY+DL L+H+P    P     
Sbjct: 74  GLVASRADVFVTSKLWCSDLHA-GRVVPAARETLRNLGMDYVDLLLVHWPATVAPGSYDF 132

Query: 437 ----DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
               ++     D    W+GM++  +LGLAR+IGVSNF+A ++ +L+S + +RP  NQ+E
Sbjct: 133 PFPKEEMAPAFDMEGVWRGMEECHRLGLARAIGVSNFSAKKLEQLLSFAVVRPAANQVE 191


>UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28;
           Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza
           sativa (Rice)
          Length = 323

 Score =  138 bits (335), Expect = 7e-32
 Identities = 75/186 (40%), Positives = 113/186 (60%), Gaps = 9/186 (4%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P + L  G   P+ A+G G   +  + S +  R A   A+E G+RH DTAA+Y  E  +G
Sbjct: 5   PEVALRHGAGRPMPAVGVGTADSAAT-SPETKRGAALAALEVGFRHFDTAALYGTEAPLG 63

Query: 251 QGIAEAIANGLV-TREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427
           + IAEA   GLV +REE+FVTTKLW  +     V+P+L+ESL+ L ++Y+DLYL+H+PI+
Sbjct: 64  EAIAEATRRGLVASREEVFVTTKLWCTQCHPGLVLPSLRESLRNLQMEYVDLYLVHWPIS 123

Query: 428 TKPD--------DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRP 583
            KP         +     D+   W+ M++  +LGLA++IGVSNF    + +L++ + I P
Sbjct: 124 VKPGPPMLPVKREDAVPFDFEGVWRAMEECHRLGLAKAIGVSNFTTKHLDKLLAVATIPP 183

Query: 584 GXNQIE 601
             NQ+E
Sbjct: 184 AVNQVE 189


>UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone
           synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent
           6'-deoxychalcone synthase - Glycine max (Soybean)
          Length = 315

 Score =  138 bits (335), Expect = 7e-32
 Identities = 72/191 (37%), Positives = 121/191 (63%), Gaps = 8/191 (4%)
 Frame = +2

Query: 53  AMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQ 232
           A A++ P I   + +    + +  G G+A +     + ++A+  A++ GYRH DTAA Y 
Sbjct: 2   AAAIEIPTIVFPNSSAQQRMPV-VGMGSAPDFTCKKDTKEAIIEAVKQGYRHFDTAAAYG 60

Query: 233 DEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLI 412
            E+ +G+ + EAI  GLV+R++LFVT+KLW  ++    V+PAL++SLK L L+Y+DLYLI
Sbjct: 61  SEQALGEALKEAIHLGLVSRQDLFVTSKLWVTENHPHLVLPALRKSLKTLQLEYLDLYLI 120

Query: 413 HFPIATKPD--DSPDNI------DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSN 568
           H+P++++P     P  +      D    W+ M++ ++LGL ++IGVSNF+  ++  L+S 
Sbjct: 121 HWPLSSQPGKFSFPIEVEDLLPFDVKGVWESMEECQKLGLTKAIGVSNFSVKKLQNLLSV 180

Query: 569 SYIRPGXNQIE 601
           + IRP  +Q+E
Sbjct: 181 ATIRPVVDQVE 191


>UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3;
           Lactobacillus|Rep: 2,5-didehydrogluconate reductase -
           Lactobacillus reuteri 100-23
          Length = 288

 Score =  138 bits (334), Expect = 9e-32
 Identities = 82/174 (47%), Positives = 104/174 (59%), Gaps = 1/174 (0%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
           LN+G  IP V  GT R  A      D   QAV  AIE GYRHIDTAAVY +EE VG+GI 
Sbjct: 13  LNNGVKIPCVGYGTFRTPA------DVAEQAVKEAIETGYRHIDTAAVYGNEEAVGKGIK 66

Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-D 439
           ++   G + RE+LFVT+KLWN     +Q   A QE+L +L +DY+DLYLIH+P   K   
Sbjct: 67  DS---G-IKREDLFVTSKLWNTNRGYEQTKKAFQETLDRLQMDYLDLYLIHWPANEKQFG 122

Query: 440 DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
           D    I+  ETW+ M+D    G  R+IGVSNF    I  L+  + + P  +QIE
Sbjct: 123 DDAAKIN-AETWRAMEDLYNEGKIRAIGVSNFMPHHIAELMKTAKVAPAVDQIE 175


>UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium
           discoideum|Rep: Aldehyde reductase - Dictyostelium
           discoideum AX4
          Length = 297

 Score =  138 bits (334), Expect = 9e-32
 Identities = 75/186 (40%), Positives = 114/186 (61%), Gaps = 9/186 (4%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P  +L+ G+ IP+V    G GT K   ++  V +AV  A++AGYRHID AAVY +E++VG
Sbjct: 3   PSFKLSSGHKIPLV----GFGTWKAETTL--VGKAVEVALDAGYRHIDCAAVYLNEKEVG 56

Query: 251 QGIAEAIAN-GLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427
           +   +       V RE++F+T+KLWN  H ++ V PAL+ +L  LGL Y+DLYL+H+P+A
Sbjct: 57  EAFTKKFTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVHWPVA 116

Query: 428 ---TKPD-----DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRP 583
              T  D      + + +   ETW+ M+     GL +SIG+SNFN   +  ++S + I+P
Sbjct: 117 FEYTSNDIQTSGSTQEFVSIRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYARIKP 176

Query: 584 GXNQIE 601
             NQ+E
Sbjct: 177 AANQVE 182


>UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae
           str. PEST
          Length = 319

 Score =  138 bits (333), Expect = 1e-31
 Identities = 76/198 (38%), Positives = 118/198 (59%), Gaps = 16/198 (8%)
 Frame = +2

Query: 56  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235
           M+ Q P ++ ++G  IP+  LG G   A++   ++ V++A    I+ GYRHIDTA +Y++
Sbjct: 1   MSTQVPTVRFSNGYEIPV--LGYGTYLAQKGQCVELVKKA----IDLGYRHIDTAFLYEN 54

Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415
           E ++GQ I + IA G++ RE++FVTTKLWN  H    V  A + S   L + YIDL+L+H
Sbjct: 55  EVEIGQAIRDKIAEGVIRREDVFVTTKLWNTFHDPQHVEEAFRRSFDMLDIGYIDLFLMH 114

Query: 416 FPIAT----------KPDDSPDN-----IDYLETWQGMQD-ARQLGLARSIGVSNFNATQ 547
            P+            +P D+  N     +DY+ETW+ M+      G  RSIG+SNFN+ Q
Sbjct: 115 SPMGVQFSGYEYADMQPKDAAGNMLFSDVDYVETWKAMEKLVTAGGRVRSIGLSNFNSEQ 174

Query: 548 ITRLVSNSYIRPGXNQIE 601
           I R++  + ++P  NQ+E
Sbjct: 175 IERILQIATVKPVNNQVE 192


>UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2;
           Corynebacterium|Rep: Putative oxidoreductase -
           Corynebacterium diphtheriae
          Length = 290

 Score =  137 bits (332), Expect = 2e-31
 Identities = 73/177 (41%), Positives = 107/177 (60%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P I LNDG  +P +  GT +   +E D+   VR A    IE GYRHIDTA++Y++EE+VG
Sbjct: 12  PTITLNDGTEMPAIGFGTYK--LREQDAYRAVRSA----IEVGYRHIDTASLYKNEEEVG 65

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430
           + +A+AI  G V R+ELF+TTK+WND H       + QESL +LGLDYID  ++H+P   
Sbjct: 66  RAVADAITAGEVARDELFITTKVWNDMHGDQLTQRSFQESLHRLGLDYIDCCMVHWP--- 122

Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                P    Y+E++  +   + LG  +S+ V+NF    +  +V+ + I P  NQ+E
Sbjct: 123 ----WPQKGLYVESFAALAKIQGLGQLQSVAVANFYPEVLREIVAETGIAPVLNQVE 175


>UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep:
           Aldehyde reductase - Leptospira interrogans
          Length = 278

 Score =  136 bits (330), Expect = 3e-31
 Identities = 75/175 (42%), Positives = 108/175 (61%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           I LN+G ++PI+ LG  +     + S  E ++AV  A+EAGYRHIDTA +Y +E  VGQ 
Sbjct: 12  IMLNNGISMPILGLGVWK-----TKSGKECKEAVLNALEAGYRHIDTARIYDNEVDVGQA 66

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
           I E+   G + R+E+F+TTKLWN     D+   AL+ SL +LG+D++DLYLIHFP+ +K 
Sbjct: 67  IRES---G-IPRKEIFITTKLWNADQGSDKTRKALENSLDRLGIDFVDLYLIHFPVTSKR 122

Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
            DS         W+ ++      L ++IGVSN+    +T L+ NS I P  NQ+E
Sbjct: 123 MDS---------WKELEKLYHDKLCKAIGVSNYTIIHLTELLKNSQITPAVNQVE 168


>UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 322

 Score =  136 bits (330), Expect = 3e-31
 Identities = 75/192 (39%), Positives = 116/192 (60%)
 Frame = +2

Query: 26  ITLTCLLNAAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYR 205
           +T + +++  ++ Q   I+LN+G  IP VALG  +     +D   E   A  WA +AGYR
Sbjct: 4   VTASGIISGNISTQR--IKLNNGQEIPQVALGVYKAP---NDGSTE--NACKWAFDAGYR 56

Query: 206 HIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLG 385
           HID+AA Y +EE VG+ +AE      V R E+F+T+KLW+  H  D+   A+++SLKKL 
Sbjct: 57  HIDSAARYMNEESVGRALAEWTKENNVPRSEIFITSKLWDADH--DKAAAAIEDSLKKLN 114

Query: 386 LDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVS 565
           +DY+D+YL+H P     +        LE W+ +++A   G  ++IGVSNF+  ++  L++
Sbjct: 115 VDYMDMYLMHSPGTMGAEKR------LEAWKALEEAVDAGKIKTIGVSNFDVEELDHLLA 168

Query: 566 NSYIRPGXNQIE 601
           N  I+P  NQIE
Sbjct: 169 NCRIKPAVNQIE 180


>UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate
           division TM7 genomosp. GTL1|Rep: Aldehyde reductase -
           candidate division TM7 genomosp. GTL1
          Length = 299

 Score =  136 bits (328), Expect = 5e-31
 Identities = 75/187 (40%), Positives = 114/187 (60%), Gaps = 12/187 (6%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGR-GTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
           + L +  T+P++  GT    T   +D ++        AI+AGYRHID A +Y +E++VG+
Sbjct: 4   LTLRNKQTLPLLGYGTWELPTGTTADLVET-------AIKAGYRHIDCAMIYGNEKEVGE 56

Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
           GI   I  G+V RE+LFVT+KLWN  HA+  V  A +++L  LGLDY+DLYLIH+ +A +
Sbjct: 57  GIRRTIDQGVVKREDLFVTSKLWNTDHAQVDVGVACRKTLNDLGLDYLDLYLIHWGVAFE 116

Query: 434 PDDSPDNID-----------YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 580
             D+ + +D             ETWQ M++  + GL +S+GV+NF A  +  L+S + I+
Sbjct: 117 HGDNLEPLDDDGVAKFSFISMKETWQAMEELVEQGLVKSMGVANFTAPMLLDLLSYAKIK 176

Query: 581 PGXNQIE 601
           P  +QIE
Sbjct: 177 PAVHQIE 183


>UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes
           aegypti|Rep: Aldo-keto reductase - Aedes aegypti
           (Yellowfever mosquito)
          Length = 303

 Score =  136 bits (328), Expect = 5e-31
 Identities = 74/183 (40%), Positives = 113/183 (61%), Gaps = 8/183 (4%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           + LN+G++IP + LGT + T   SD +  ++ AV    E GYR IDTA VY +E+ VGQ 
Sbjct: 2   LALNNGHSIPPIGLGTYKITG--SDGVAAIKSAV----EFGYRLIDTAFVYNNEQVVGQA 55

Query: 257 IAEAIANGL-VTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
           + E  + G  + RE++F+ +KL    H  + V    + SL++LGLDY+DLYL+H P+A +
Sbjct: 56  LREIFSQGNDINREDVFIVSKLGPTFHRPEAVEKGCRLSLERLGLDYVDLYLMHTPVAAR 115

Query: 434 PD-------DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXN 592
                    +  D +  LETW+ +++ ++ GL RSIGVSNFN  Q+  +V++  IRP  N
Sbjct: 116 DSGDGNDRSEIDDEVTPLETWKALEECQRKGLVRSIGVSNFNEEQLMEIVTHGSIRPVVN 175

Query: 593 QIE 601
           Q+E
Sbjct: 176 QVE 178


>UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC
           1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase);
           n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid
           4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid
           5-beta-reductase) - Homo sapiens (Human)
          Length = 326

 Score =  136 bits (328), Expect = 5e-31
 Identities = 76/188 (40%), Positives = 110/188 (58%), Gaps = 13/188 (6%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           I L+DGN+IPI+ LGT   +  +S        +V  AI+ GYRHID A +YQ+E +VG+ 
Sbjct: 10  IPLSDGNSIPIIGLGTY--SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEA 67

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
           I E IA G V RE++F   KLW   H  + V P L+ +L+ L LDY+DLY+I  P+A KP
Sbjct: 68  IREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKP 127

Query: 437 DDS----PDNIDYL-------ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 577
            D      +N  +L        TW+ M+  +  GL +S+GVSNFN  Q+  +++   +  
Sbjct: 128 GDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKH 187

Query: 578 RPGXNQIE 601
           +P  NQ+E
Sbjct: 188 KPVSNQVE 195


>UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;
           Corynebacterineae|Rep: 2,5-didehydrogluconate reductase
           - Mycobacterium sp. (strain KMS)
          Length = 283

 Score =  135 bits (326), Expect = 9e-31
 Identities = 77/181 (42%), Positives = 112/181 (61%)
 Frame = +2

Query: 59  AVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDE 238
           A   P + LNDG++IP++ LG G  +  E++      ++V  A+EAGYR IDTAAVY +E
Sbjct: 8   AAGIPSVSLNDGHSIPVLGLGVGELSEAEAE------RSVAAALEAGYRLIDTAAVYGNE 61

Query: 239 EQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 418
             VG+ +    A+G + REE++VTTKL            A + SL++LGLDY+DLYLIH+
Sbjct: 62  AAVGRAVN---ASG-IPREEIYVTTKLAVADQGFGTSQDAARASLERLGLDYVDLYLIHW 117

Query: 419 PIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598
           P         D+  Y+++W G+  A+Q G+ARSIGV NFNA  ++ ++  S+  P  NQI
Sbjct: 118 PAG-------DHGKYIDSWGGLMKAKQDGVARSIGVCNFNAEHLSNIIDLSFFTPAINQI 170

Query: 599 E 601
           E
Sbjct: 171 E 171


>UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep:
           Aldose reductase - Mus musculus (Mouse)
          Length = 316

 Score =  134 bits (325), Expect = 1e-30
 Identities = 75/188 (39%), Positives = 111/188 (59%), Gaps = 13/188 (6%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           ++LN+G  +P + LGT +          +V +AV  AI+ GYRHID A VYQ+E++VG  
Sbjct: 5   LELNNGTKMPTLGLGTWKSPP------GQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVA 58

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
           + E +   +V R++LF+ +KLW   H +  V  A Q++L  L LDY+DLYLIH+P   KP
Sbjct: 59  LQEKLKEQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKP 118

Query: 437 -------DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 577
                  D S    P + D+++TW  M+     GL ++IGVSNFN  QI R+++   +  
Sbjct: 119 GPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKY 178

Query: 578 RPGXNQIE 601
           +P  NQIE
Sbjct: 179 KPAVNQIE 186


>UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;
           n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
           A - Photorhabdus luminescens subsp. laumondii
          Length = 292

 Score =  134 bits (324), Expect = 2e-30
 Identities = 76/177 (42%), Positives = 109/177 (61%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P I+L DGN +P + LG+       SD   ++ + ++ A++ GYR IDTAA+Y +E+ VG
Sbjct: 5   PIIRLADGNHMPQLGLGSWA-----SDD-QQIAETIHAALDIGYRAIDTAAIYNNEKGVG 58

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430
             + E      + RE++FVTTKLWND+H   +   AL ESL+KL LDY+DLYLIH+P   
Sbjct: 59  NALQETD----IPREDIFVTTKLWNDRHLDARA--ALTESLEKLQLDYVDLYLIHWP--- 109

Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
               +P    Y+  WQ + + ++ GL RSIGVSNF    I RL++ + + P  NQIE
Sbjct: 110 ----APPQDQYVGAWQQLIELQKEGLIRSIGVSNFQPEHIQRLINETGVHPVINQIE 162


>UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+)
           <=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep:
           Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
           + NADPH - Aspergillus niger
          Length = 323

 Score =  134 bits (323), Expect = 2e-30
 Identities = 81/184 (44%), Positives = 110/184 (59%), Gaps = 11/184 (5%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
           +N G  IP V  GT +  AK      EV  AV  A+  GYRHID AA+Y++E +VG GI 
Sbjct: 9   INTGAKIPAVGFGTWQ--AKPL----EVENAVEVALREGYRHIDCAAIYRNETEVGNGIR 62

Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 442
           ++   G V REE+F+T KLWN KHA + V PAL ++L+ LG+ Y+DLYL+H+P A K  D
Sbjct: 63  KS---G-VPREEIFITGKLWNTKHAPEDVEPALDKTLQDLGVAYLDLYLMHWPCAFKGGD 118

Query: 443 -----SPD------NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGX 589
                + D      NIDY+ T++ M+     G  R+IGVSNFN  ++  L+    + P  
Sbjct: 119 KWFPLNDDGVFDLANIDYITTYRAMEKLLATGKVRAIGVSNFNIRRLEELLGQVSVVPAV 178

Query: 590 NQIE 601
           NQIE
Sbjct: 179 NQIE 182


>UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate
           dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent
           D-sorbitol-6-phosphate dehydrogenase - Malus domestica
           (Apple) (Malus sylvestris)
          Length = 310

 Score =  133 bits (322), Expect = 3e-30
 Identities = 75/190 (39%), Positives = 107/190 (56%), Gaps = 15/190 (7%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           + L+ G  +P++ LG  R         DE+++ +  AI+ GYRH D AA Y+ E  VG+ 
Sbjct: 4   VTLSSGYEMPVIGLGLWRLEK------DELKEVILNAIKIGYRHFDCAAHYKSEADVGEA 57

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
           +AEA   GLV REELF+TTK+WN  H    VV A + SL+KL +DY+DLYL+H+P+ TK 
Sbjct: 58  LAEAFKTGLVKREELFITTKIWNSDHG--HVVEACKNSLEKLQIDYLDLYLVHYPMPTKH 115

Query: 437 D---------------DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 571
           +               D    I   +TW+GM+    LGL RSIG+SN+        ++ S
Sbjct: 116 NAIGKTASLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSNYELFLTRDCLAYS 175

Query: 572 YIRPGXNQIE 601
            I+P  +Q E
Sbjct: 176 KIKPAVSQFE 185


>UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
           Aldehyde reductase - Opitutaceae bacterium TAV2
          Length = 347

 Score =  133 bits (321), Expect = 4e-30
 Identities = 73/204 (35%), Positives = 113/204 (55%), Gaps = 13/204 (6%)
 Frame = +2

Query: 29  TLTCLLNAAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRH 208
           T T  L      + P   L  G  +P + +GT      +  +  EV  +VY A E GYRH
Sbjct: 3   TETATLAPIDPAKIPQRTLASGARMPAIGMGT---FGSDHAAPGEVAASVYAAAELGYRH 59

Query: 209 IDTAAVYQDEEQVGQGIAEAI-ANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLG 385
            D AAVY +E ++G      + +N  + RE+L++T+KLWNDKHA   V+PA ++SL+ LG
Sbjct: 60  FDCAAVYSNEREIGATFRRILTSNTGIRREDLWITSKLWNDKHAEADVIPAFEKSLRDLG 119

Query: 386 LDYIDLYLIHFPI-----------ATKPDDSP-DNIDYLETWQGMQDARQLGLARSIGVS 529
           LDY+DLYLIH+P            +  PD  P  + ++++TW+ ++     GL R IG S
Sbjct: 120 LDYLDLYLIHWPFPNFHPPGCDVSSRSPDARPYIHAEFMKTWRQLETLHDRGLVRHIGTS 179

Query: 530 NFNATQITRLVSNSYIRPGXNQIE 601
           N    ++  L+ ++ +RP  N++E
Sbjct: 180 NMTIAKLQLLLRDARVRPAVNEME 203


>UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;
           n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
           A - Yersinia pestis
          Length = 277

 Score =  133 bits (321), Expect = 4e-30
 Identities = 77/177 (43%), Positives = 103/177 (58%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P I+L DG  +P + LG  +       SI E   AV  A+E GYR IDTAA+Y++EE   
Sbjct: 5   PLIKLYDGRLMPQLGLGVWQA------SIQETELAVSKALEVGYRSIDTAAIYKNEE--- 55

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430
            G+ +A+    V R+ELF+TTKLWND     Q   AL+ SL+KL LDY+DLYLIH+P   
Sbjct: 56  -GVGKALKAAAVARDELFITTKLWNDDQHNPQ--QALETSLQKLQLDYVDLYLIHWP--- 109

Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                P    Y+  W+ +   ++ GL RSIGV NF+   + RL+  + I P  NQIE
Sbjct: 110 ----DPKQDHYVSAWRELVTLKEQGLIRSIGVCNFHIPHLQRLIDETGIAPTVNQIE 162


>UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13;
           Pezizomycotina|Rep: Aldehyde reductase - Coccidioides
           posadasii
          Length = 314

 Score =  132 bits (320), Expect = 5e-30
 Identities = 76/193 (39%), Positives = 114/193 (59%), Gaps = 11/193 (5%)
 Frame = +2

Query: 56  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235
           MA +    +LN G  IP +  GT +    + D       AV  A+ AGYRHIDTAAVY  
Sbjct: 1   MASRHTTFRLNTGEDIPAIGFGTWQDENAQED-------AVLTALSAGYRHIDTAAVYGT 53

Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415
           E+ +G+    A+A   ++R+ELF+T+KLWN+KH  + V  A+ +SLK L +DY+DLYL+H
Sbjct: 54  EKAIGR----ALARSRLSRDELFITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMH 109

Query: 416 FPIATK------PDDSPDN-----IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 562
           +P A        P DS  N     IDY++T++ M+   + G  ++IG+SNF+  ++ RL+
Sbjct: 110 WPAAFAPGDDMFPKDSQGNSKTVDIDYVDTYKAMEKLVKSGKTKAIGISNFSKGEMERLL 169

Query: 563 SNSYIRPGXNQIE 601
            +  I P   Q+E
Sbjct: 170 ESCSIVPAVMQME 182


>UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep:
           Aldose reductase - Homo sapiens (Human)
          Length = 316

 Score =  132 bits (320), Expect = 5e-30
 Identities = 76/186 (40%), Positives = 109/186 (58%), Gaps = 13/186 (6%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
           LN+G  +PI+ LGT +          +V +AV  AI+ GYRHID A VYQ+E +VG  I 
Sbjct: 7   LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60

Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 436
           E +   +V REELF+ +KLW   H +  V  A Q++L  L LDY+DLYLIH+P   KP  
Sbjct: 61  EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120

Query: 437 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 583
                D+S    P + + L+TW  M++    GL ++IG+SNFN  Q+  +++   +  +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180

Query: 584 GXNQIE 601
             NQIE
Sbjct: 181 AVNQIE 186


>UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7;
           cellular organisms|Rep: Prostaglandin f synthase,
           putative - Leishmania major
          Length = 279

 Score =  132 bits (319), Expect = 6e-30
 Identities = 72/182 (39%), Positives = 110/182 (60%)
 Frame = +2

Query: 56  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235
           MAV+   + L++G  +P   LG G   AK+ + +  ++    WA+ AGYRH+DTA  Y++
Sbjct: 1   MAVKCTHVTLSNGVQVP--QLGIGTWEAKDGNEVVNIK----WAVNAGYRHVDTAHYYKN 54

Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415
           E+ VGQGI+E    G V R ++FVTTKLWN  H  +  + A ++S + LG++Y+DLYLIH
Sbjct: 55  EKGVGQGISEC---G-VPRSDIFVTTKLWNYDHGYESALAAFEQSRQALGVEYVDLYLIH 110

Query: 416 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQ 595
           +P        P N  Y+ETW+  +   ++   R+IGVSNF    +  L++N  + P  NQ
Sbjct: 111 WP-------GP-NRSYIETWRAFEKLYEMKKVRAIGVSNFEPHHLDDLLANCTVPPMVNQ 162

Query: 596 IE 601
           +E
Sbjct: 163 VE 164


>UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila
           melanogaster|Rep: CG40064-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 361

 Score =  132 bits (318), Expect = 8e-30
 Identities = 66/155 (42%), Positives = 96/155 (61%), Gaps = 12/155 (7%)
 Frame = +2

Query: 173 AVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVV 352
           AV+ AIE G+RH DTA  Y++E+++G+ +   I  G ++RE +F+TTKLWN  H    V 
Sbjct: 49  AVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMGNISRENIFLTTKLWNTHHDPRDVR 108

Query: 353 PALQESLKKLGLDYIDLYLIHFPIATK--------PDDSPD----NIDYLETWQGMQDAR 496
              ++ L+ LG  YIDLYL+HFP+  K        P    +     IDYL+TW+ M++  
Sbjct: 109 RICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMSGDELQTVEIDYLDTWRAMENLV 168

Query: 497 QLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
           +LG+ RSIG+SNFN  QI R++  S  +P  NQ+E
Sbjct: 169 KLGMVRSIGLSNFNMEQIQRIIQCSSSKPVVNQVE 203


>UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1;
           Corynebacterium jeikeium K411|Rep: Putative
           oxidoreductase - Corynebacterium jeikeium (strain K411)
          Length = 285

 Score =  131 bits (317), Expect = 1e-29
 Identities = 77/177 (43%), Positives = 102/177 (57%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P +++NDG T P   LG G     + D+   VR A    IE GYRHIDTAA+Y +EE VG
Sbjct: 9   PTLEMNDGKTTP--QLGLGVWQLSDEDTYTSVRAA----IETGYRHIDTAAIYGNEEAVG 62

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430
           + +A+A+  G V REELF+TTKLWN   A  +   A  ES KKLG+DY+DLYL+H+P   
Sbjct: 63  RAVADAVKAGDVQREELFITTKLWNADQACGK--EAFAESQKKLGMDYVDLYLLHWP--- 117

Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                P    +++ +  M + +Q G A SIGV NF    +  L    +  P  NQIE
Sbjct: 118 ----CPQADSFVQAYDSMAEIQQSGGATSIGVCNFYPEALDALKQAGH-TPAVNQIE 169


>UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 337

 Score =  131 bits (317), Expect = 1e-29
 Identities = 76/180 (42%), Positives = 102/180 (56%), Gaps = 5/180 (2%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           I +ND N + I  +G G   A+ +    EVR AV  A+ AGY H+D AA Y +E +VG+ 
Sbjct: 6   ILVNDANGLRIPRVGLGTWKARPN----EVRDAVRDALGAGYAHVDCAAAYANESEVGEA 61

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
           + EA   G   RE++FVT+KLWND+     V  AL  +L  LG+ Y+DLYLIH+P+A K 
Sbjct: 62  LREAFERGDAKREDVFVTSKLWNDRRRPRDVREALMTTLNDLGVGYLDLYLIHWPVAWKR 121

Query: 437 DD--SPD-NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSN--SYIRPGXNQIE 601
                PD      E W  ++     GL R IGVSNFN  Q+  L  +  + I+P  NQIE
Sbjct: 122 GTVLQPDAEASIAECWSELERCVADGLVRHIGVSNFNEAQLAALCDDPRTKIQPACNQIE 181


>UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 333

 Score =  130 bits (315), Expect = 2e-29
 Identities = 70/188 (37%), Positives = 110/188 (58%), Gaps = 13/188 (6%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           + L  G+ +P+V LGT +  A      DEV  A+  A++AGYRH D A +Y +E++VG  
Sbjct: 5   VTLPSGHAMPLVGLGTWKLKA------DEVAGAIGAAVDAGYRHFDCALIYGNEKEVGVA 58

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA--- 427
           + EA+    + RE++F+TTK+WN  HA++ V      SL  L LDYIDLY++H+P+    
Sbjct: 59  LREAMQRLGLKREDVFITTKVWNTFHAKEDVAECFNRSLTDLQLDYIDLYIMHWPLGFQN 118

Query: 428 ---------TKPDDSP-DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 577
                    T+  D    ++ YLETW  M+D  + G  +S+G+SNFN+ Q+  ++ +S +
Sbjct: 119 LGPTVMFPRTETGDIVYSDVHYLETWSAMEDLVKTGKCKSLGLSNFNSKQLDDVLQHSTV 178

Query: 578 RPGXNQIE 601
            P   Q+E
Sbjct: 179 PPSVLQVE 186


>UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep:
           Aldehyde reductase 1 - Sporobolomyces salmonicolor
          Length = 323

 Score =  130 bits (315), Expect = 2e-29
 Identities = 76/189 (40%), Positives = 109/189 (57%), Gaps = 16/189 (8%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
           LN G ++ +V  GT +          EV Q V  AIE GYRH+D A VY ++ +VG  I 
Sbjct: 7   LNTGASLELVGYGTWQAAP------GEVGQGVKVAIETGYRHLDLAKVYSNQPEVGAAIK 60

Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD- 439
           EA   G V RE+LF+T+KLWN+ H  +QV PAL ++LK+LGL+Y+DLYLIH+P+A  P+ 
Sbjct: 61  EA---G-VKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHWPVAFPPEG 116

Query: 440 DSPDN---------------IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 574
           D   N               +  ++TW+ M      G  ++IGVSNF+A  +  ++  + 
Sbjct: 117 DITQNLFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKAIGVSNFDAKMVDAIIEATG 176

Query: 575 IRPGXNQIE 601
           + P  NQIE
Sbjct: 177 VTPSVNQIE 185


>UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium
           discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
           discoideum AX4
          Length = 321

 Score =  130 bits (314), Expect = 2e-29
 Identities = 76/190 (40%), Positives = 110/190 (57%), Gaps = 16/190 (8%)
 Frame = +2

Query: 80  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259
           +LNDGN IP + LGT       S++  EV  A+  A++ GYRHID AA Y +E+ +G  +
Sbjct: 18  KLNDGNQIPSIGLGT-----YYSENPGEVGDAINNALKNGYRHIDGAAFYGNEKVIGNSL 72

Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA---T 430
            E    G + RE++F T+KLWN  H  + VV    ++++ LG+ Y+DLYLIH+PIA   +
Sbjct: 73  KEIFKEGEIKREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPIAFENS 132

Query: 431 KP--------DDSPDN-----IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 571
            P         D   N     +   ETWQ M+   +LGL +SIGVSNFN   +  L++ +
Sbjct: 133 NPLGLTIEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVDLLTYA 192

Query: 572 YIRPGXNQIE 601
            I+P  NQ+E
Sbjct: 193 KIKPVVNQVE 202


>UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC
           700755|Rep: YvgN - Psychroflexus torquis ATCC 700755
          Length = 280

 Score =  130 bits (313), Expect = 3e-29
 Identities = 79/175 (45%), Positives = 103/175 (58%), Gaps = 2/175 (1%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
           LNDGN IPIV  GT +  A E + I  ++++   A+  GYR IDT A+YQ+EE VG+ I 
Sbjct: 5   LNDGNRIPIVGFGTYK--ANEEEGIKSIQKS---ALTLGYRLIDTVAIYQNEEAVGKAIK 59

Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP--IATKP 436
              A G V REE+FVTTKLW +     Q   AL ESL+KL L+YIDLYLIH+P       
Sbjct: 60  ---ARG-VLREEIFVTTKLWRENLGYKQTRIALDESLRKLDLNYIDLYLIHWPANAINYK 115

Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
           D    N D   TW+ M++ +  G  +S+GVSNF    +  L   + + P  NQIE
Sbjct: 116 DWQKTNAD---TWRAMEELQAEGKIKSLGVSNFWPEHLEALFQTAKVSPSVNQIE 167


>UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG03517.1 - Gibberella zeae PH-1
          Length = 364

 Score =  129 bits (312), Expect = 4e-29
 Identities = 73/196 (37%), Positives = 118/196 (60%), Gaps = 3/196 (1%)
 Frame = +2

Query: 23  IITLTCLLNAAMAVQAPCIQLNDGNTI-PIVALGTGRGTAKESDSIDEVRQAVYWAIEAG 199
           ++T T L  A     A   + N   T+  I A G G   A +      V  AV +A++ G
Sbjct: 31  LVTYTILSIATSFGPAEMPEFNKNETVRDIPAFGLGTWLAGKG----VVVPAVEYALKGG 86

Query: 200 YRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKK 379
           YRHIDTA ++++E++VG+GI    A+G V+R+E++VT KLWN  H  + V  A++ S+  
Sbjct: 87  YRHIDTALIWRNEDEVGKGIK---ASG-VSRDEIWVTGKLWNTDHRPELVRKAIETSIAN 142

Query: 380 LGLDYIDLYLIHFPIATKPD--DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQIT 553
           LG++Y+DLYLIH+P+A  P+  D  +N   ++TW+ M++  + GL R+IG SNF    I 
Sbjct: 143 LGVEYLDLYLIHYPVAWVPETRDVDNNTSLIDTWKAMEELVRAGLTRNIGFSNFAPKDIN 202

Query: 554 RLVSNSYIRPGXNQIE 601
           +++  + I+P  ++ E
Sbjct: 203 KILKIASIQPYAHEFE 218


>UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2;
           Schizosaccharomyces pombe|Rep: Probable oxidoreductase
           C26F1.07 - Schizosaccharomyces pombe (Fission yeast)
          Length = 321

 Score =  129 bits (311), Expect = 6e-29
 Identities = 74/184 (40%), Positives = 113/184 (61%), Gaps = 11/184 (5%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
           L DG+ IP + LGT R    ++      + AV  A++ GYRHID AA+Y +E++VG GI 
Sbjct: 18  LADGSKIPGLGLGTWRSEPNQT------KNAVKTALQYGYRHIDAAAIYGNEDEVGDGIK 71

Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK--- 433
           E+   G V R++++VT+KLW + HA + V  AL+++LK L LDY+D YLIH+P++ K   
Sbjct: 72  ES---G-VPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGE 127

Query: 434 ---PDDSPDNIDY-----LETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGX 589
              P D   N+ Y      ETW+ M+   + G  R IG+SNFN T + R++  + ++P  
Sbjct: 128 DKFPKDKDGNLIYEKNPIEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAKVKPAV 187

Query: 590 NQIE 601
           +Q+E
Sbjct: 188 HQME 191


>UniRef50_P22045 Cluster: Probable reductase; n=101; cellular
           organisms|Rep: Probable reductase - Leishmania major
          Length = 284

 Score =  129 bits (311), Expect = 6e-29
 Identities = 72/180 (40%), Positives = 107/180 (59%)
 Frame = +2

Query: 62  VQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEE 241
           V    + L++G  +P   LG  +  A E         AV WA+ AGYRHIDTAA+Y++EE
Sbjct: 4   VDKAMVTLSNGVKMPQFGLGVWQSPAGEV-----TENAVNWALCAGYRHIDTAAIYKNEE 58

Query: 242 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 421
            VG G+    A+G V RE++F+TTKLWN +   +  + A +ES +KLG+DYIDLYLIH+P
Sbjct: 59  SVGAGLR---ASG-VPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWP 114

Query: 422 IATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
              K   S +   YL++W+  +   +    R+IGVSNF+   +  +++   + P  NQ+E
Sbjct: 115 -RGKDILSKEGKKYLDSWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTPMVNQVE 173


>UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep:
           Protein GCY - Saccharomyces cerevisiae (Baker's yeast)
          Length = 312

 Score =  128 bits (309), Expect = 1e-28
 Identities = 80/196 (40%), Positives = 121/196 (61%), Gaps = 21/196 (10%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           + LN G  IP + LGT +  +KE+D+     +AV  A++ GYRHIDTAA+Y++E+QVGQ 
Sbjct: 12  LSLNTGAQIPQIGLGTWQ--SKENDAY----KAVLTALKDGYRHIDTAAIYRNEDQVGQ- 64

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP----- 421
              AI +  V REE+FVTTKLW  +H   +V  AL +SLK+LGLDY+DLYL+H+P     
Sbjct: 65  ---AIKDSGVPREEIFVTTKLWCTQHHEPEV--ALDQSLKRLGLDYVDLYLMHWPARLDP 119

Query: 422 ----------IATKPDDSP----DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRL 559
                     + TK D S      N ++++TW+ MQ+  + G  +++GVSNF+   +  L
Sbjct: 120 AYIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDL 179

Query: 560 VSN--SYIRPGXNQIE 601
           +++  + + P  NQ+E
Sbjct: 180 LASQGNKLTPAANQVE 195


>UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30;
           Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus
           (Mouse)
          Length = 316

 Score =  128 bits (308), Expect = 1e-28
 Identities = 77/191 (40%), Positives = 109/191 (57%), Gaps = 13/191 (6%)
 Frame = +2

Query: 68  APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247
           A  + L  G  +PIV LGT +    +      VR+AV  AI+AGYRHID A VYQ+E +V
Sbjct: 2   AAFVTLLTGAKMPIVGLGTWKSPPAK------VREAVKVAIDAGYRHIDCAYVYQNESEV 55

Query: 248 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427
           G+ I E I    V RE+LF+ +KLW+    +  V  A Q +L  L LDY+DLYLIH+P  
Sbjct: 56  GEAIQEKIQEKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQG 115

Query: 428 TK------PDDSPDNI-----DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 574
            +      P D   +I      +L+ W+ M++    GL +++GVSNFN  QI RL++   
Sbjct: 116 FQSGNVFLPTDDKGSILSSKYTFLDAWEAMEELVDQGLVKALGVSNFNHFQIERLLNKPG 175

Query: 575 I--RPGXNQIE 601
           +  +P  NQ+E
Sbjct: 176 LKHKPVTNQVE 186


>UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1;
           Orconectes limosus|Rep: Aldoketoreductase-like protein -
           Orconectes limosus (Spinycheek crayfish)
          Length = 336

 Score =  128 bits (308), Expect = 1e-28
 Identities = 73/194 (37%), Positives = 102/194 (52%), Gaps = 10/194 (5%)
 Frame = +2

Query: 50  AAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVY 229
           A    + P I LN G+ IP++ LGTG        S + V   +  A+E GYRH D+AA Y
Sbjct: 5   AGAMTKIPTILLNSGSHIPVMGLGTGSLGRNGKMSEEAVTAVLETALECGYRHFDSAAYY 64

Query: 230 QDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYL 409
            +E  +GQ +   I+ G V REELF+TTKL    +    V   LQ+SL  L L Y+DLYL
Sbjct: 65  GNEAIIGQVLRRWISEGKVKREELFITTKLPTRGNREKDVARFLQKSLDNLRLPYVDLYL 124

Query: 410 IHFPIATKPDD----SPDNI------DYLETWQGMQDARQLGLARSIGVSNFNATQITRL 559
           +H+P      D    S D +      D    W+ M+     G  ++IG+SNFNA Q+ R+
Sbjct: 125 VHYPCGILDTDRERLSADEVTVDPTTDIHAIWRAMEAQLAAGKTKNIGLSNFNADQVQRI 184

Query: 560 VSNSYIRPGXNQIE 601
           +    +RP   Q+E
Sbjct: 185 IKGCQVRPAVLQVE 198


>UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=3; Lactobacillales|Rep: Aldo/keto
           reductase of diketogulonate reductase family -
           Leuconostoc mesenteroides subsp. mesenteroides (strain
           ATCC 8293 /NCDO 523)
          Length = 292

 Score =  127 bits (307), Expect = 2e-28
 Identities = 69/145 (47%), Positives = 90/145 (62%)
 Frame = +2

Query: 167 RQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQ 346
           +QAV  AI+ GYR IDTAA Y +E +VG+ I EAI  G+V REELFVT+K+W    +  Q
Sbjct: 29  KQAVLDAIKTGYRLIDTAASYGNEREVGEAILEAINQGIVKREELFVTSKMWVQDVSAQQ 88

Query: 347 VVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGV 526
              A+Q SL++L LDY+DLYLIH P            D    W+ M+ A + G  ++IGV
Sbjct: 89  ATAAIQSSLQRLNLDYLDLYLIHQPYN----------DVFGAWRAMESAYRSGQLKAIGV 138

Query: 527 SNFNATQITRLVSNSYIRPGXNQIE 601
           SNF+  Q+T L   S I+P  NQIE
Sbjct: 139 SNFDIAQLTNLAEFSDIKPMLNQIE 163


>UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9;
           Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti
           (Yellowfever mosquito)
          Length = 316

 Score =  127 bits (307), Expect = 2e-28
 Identities = 76/186 (40%), Positives = 105/186 (56%), Gaps = 11/186 (5%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           I   +G T+P +  GT R       S +EV +A+  A+EAGYRHIDTA VY +E+ +G+ 
Sbjct: 7   ITFENGTTMPALGFGTWRA------SDEEVEKALNEALEAGYRHIDTAPVYLNEKTIGKV 60

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
           + E +  G VTR+ELF+ TKL         V   L+ SL  L L+Y+DLY +H P     
Sbjct: 61  LKEWMDAGKVTRDELFIVTKLPPHGTRASTVEKFLKNSLDDLQLEYVDLYHVHVPFTVPE 120

Query: 437 DDSP----DNIDYLET-------WQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRP 583
            D P    D +  LET       W+ M++  + GLAR+IG+SNFN  QI R++ N  I+P
Sbjct: 121 VDGPFLVEDGLIVLETTTDHVALWKAMEEVYEAGLARNIGLSNFNQRQIQRILDNCQIKP 180

Query: 584 GXNQIE 601
              QIE
Sbjct: 181 ANLQIE 186


>UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family
           protein; n=10; Trichomonas vaginalis|Rep:
           Oxidoreductase, aldo/keto reductase family protein -
           Trichomonas vaginalis G3
          Length = 312

 Score =  127 bits (307), Expect = 2e-28
 Identities = 72/175 (41%), Positives = 104/175 (59%), Gaps = 16/175 (9%)
 Frame = +2

Query: 125 GRGTAKESDSIDEVRQAVYWAIE-AGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREEL 301
           G GT   +D   +++ A+++AIE  G RHIDTA  Y ++  +G+ + E  A G + RE++
Sbjct: 7   GFGTYLANDPA-KLKAALHYAIEECGVRHIDTAFAYYNQNVIGETLKEIFAKGKIKREDM 65

Query: 302 FVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK----------PDDSP- 448
           F+TTKLW   H +D V P L E+L +L L Y+DL+LIH PIA K          P D   
Sbjct: 66  FITTKLWCTHHRKDLVEPELHENLAQLQLSYVDLFLIHQPIAFKSLPAKDGTMMPKDEKG 125

Query: 449 ----DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
               + ID LET+  M++ ++ GL R IGVSNF+  Q+ R+  N  I+P  NQ+E
Sbjct: 126 KIQYEQIDILETYHAMEECQKKGLTRHIGVSNFSIEQLERIWFNCEIKPYANQVE 180


>UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:
           Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 289

 Score =  127 bits (306), Expect = 2e-28
 Identities = 63/150 (42%), Positives = 89/150 (59%), Gaps = 11/150 (7%)
 Frame = +2

Query: 185 AIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQ 364
           AI AGYRHIDTA  Y++E  VG  I   I  G++ R+++F+ +KLW   HA + +     
Sbjct: 9   AIAAGYRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPEDIPVCFN 68

Query: 365 ESLKKLGLDYIDLYLIHFPIATK-------PDDS----PDNIDYLETWQGMQDARQLGLA 511
           +SL  L LDY+D YL+HFP+  K       P+        +IDY++ W+GM+  +  G  
Sbjct: 69  KSLSDLQLDYLDQYLVHFPVGLKKVGDELFPERDGKILTTDIDYVDVWRGMEALKATGKV 128

Query: 512 RSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
           +SIGVSNF   QI RL+S + I P  NQ+E
Sbjct: 129 KSIGVSNFTMEQIDRLLSVAKIPPAVNQVE 158


>UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core
           eudicotyledons|Rep: T2K10.1 protein - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 176

 Score =  127 bits (306), Expect = 2e-28
 Identities = 69/162 (42%), Positives = 102/162 (62%), Gaps = 10/162 (6%)
 Frame = +2

Query: 95  NTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIA 274
           +++P++  GT      E   + E    V  AI+ GYRH DT+  YQ EE +G+ +AEA++
Sbjct: 19  HSMPVLGFGTAASPLPEPTMLKET---VIEAIKLGYRHFDTSPRYQTEEPIGEALAEAVS 75

Query: 275 NGLV-TREELFVTTKLW-NDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP---- 436
            GLV +R E FVTTKLW  D H    VVPA++ SLK L LDY+DLY+IH+P+++KP    
Sbjct: 76  LGLVRSRSEFFVTTKLWCADAHG-GLVVPAIKRSLKNLKLDYLDLYIIHWPVSSKPGKYK 134

Query: 437 ----DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 550
               +D    +D+   W  M++ ++LGLA+ IGVSNF+  ++
Sbjct: 135 FPIDEDDFMPMDFEVVWSEMEECQRLGLAKCIGVSNFSCKKL 176


>UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 316

 Score =  127 bits (306), Expect = 2e-28
 Identities = 71/186 (38%), Positives = 107/186 (57%), Gaps = 11/186 (5%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           ++LN G +IP + LGT +          EV  A+  A+ AGYRHID A VYQ++++VG+ 
Sbjct: 5   LKLNSGYSIPAIGLGTWQSKP------GEVAAAIKTAVAAGYRHIDCAHVYQNQKEVGEA 58

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP--IAT 430
           + E +  G V REELF+T+K+WN  H+  +    +   L  L L Y+DL LIH+P   A 
Sbjct: 59  LKEILDEGKVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHWPQGYAE 118

Query: 431 KPDDSP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRP 583
             +  P          ++DYLETW+  + A++ G  RSIG+SNF  +QI R+   + ++P
Sbjct: 119 GAELFPAGENGKMRYSDVDYLETWKAFEAAQKAGKCRSIGLSNFTHSQIQRVWDAAEVKP 178

Query: 584 GXNQIE 601
              Q+E
Sbjct: 179 ACLQVE 184


>UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family
           protein; n=3; Trichomonas vaginalis G3|Rep:
           Oxidoreductase, aldo/keto reductase family protein -
           Trichomonas vaginalis G3
          Length = 309

 Score =  127 bits (306), Expect = 2e-28
 Identities = 71/175 (40%), Positives = 111/175 (63%), Gaps = 16/175 (9%)
 Frame = +2

Query: 125 GRGTAKESDSIDEVRQAVYWAIE-AGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREEL 301
           G GT    D    ++ AV+ AIE +GYRH+D AA Y+++E +G+ ++E  A G V REE+
Sbjct: 8   GLGTFLAEDPA-ALKAAVHSAIEDSGYRHVDCAAYYKNQEIIGEALSEIFAKGQVKREEV 66

Query: 302 FVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA--TKPDDS---------- 445
           ++T+K+WN KH  D +V  ++++LK+L L+Y+DL L+H+  A  ++ DD           
Sbjct: 67  WITSKVWNTKHRPDLLVKDVKKTLKELKLEYLDLVLVHWACAFQSREDDEYLPRDETGKI 126

Query: 446 -PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS--YIRPGXNQIE 601
             +NID LETW+ M++   LGLA+ IGVSNF+  Q+ R+  +    I+P  NQ+E
Sbjct: 127 ITENIDILETWKAMEECYNLGLAKHIGVSNFSIEQLERMRYDPGVKIQPYCNQVE 181


>UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+)
           <=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep:
           Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
           + NADPH - Aspergillus niger
          Length = 345

 Score =  127 bits (306), Expect = 2e-28
 Identities = 80/187 (42%), Positives = 108/187 (57%), Gaps = 13/187 (6%)
 Frame = +2

Query: 80  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259
           +LN G  +P V LGT +         DEVR AV  A++ GYRHID AAVY +E++VG G+
Sbjct: 8   KLNTGYDMPAVGLGTWQSKK------DEVRDAVIAALKCGYRHIDAAAVYGNEQEVGDGM 61

Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 439
                +G V REE+F+T+KLWN  H  + V  A+ +SL  L  DY+DLYLIH+P+A +  
Sbjct: 62  R---LSG-VPREEIFLTSKLWNTHHHPENVEEAVDKSLADLQTDYLDLYLIHWPVAFRYS 117

Query: 440 DS---PDN-----IDYL-----ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 580
            +   P N     ID +     +TW  M+   + G  RSIGVSNF   +I  L+  + I 
Sbjct: 118 TTTIQPVNEQTGLIDVVDVPIKDTWAAMEKLVEKGKVRSIGVSNFTREKIEELLKTAKIT 177

Query: 581 PGXNQIE 601
           P  NQIE
Sbjct: 178 PAVNQIE 184


>UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto
           reductase family - Thermotoga maritima
          Length = 286

 Score =  126 bits (305), Expect = 3e-28
 Identities = 76/180 (42%), Positives = 104/180 (57%)
 Frame = +2

Query: 62  VQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEE 241
           +Q P + LN+G  +PI+  G  +   ++++      + VY AI+ GYR IDTAA Y +EE
Sbjct: 1   MQVPKVTLNNGVEMPILGYGVFQIPPEKTE------ECVYEAIKVGYRLIDTAASYMNEE 54

Query: 242 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 421
            VG+ I  AI  G+V REELFVTTKLW      +    A ++SLKKL L+YIDLYLIH P
Sbjct: 55  GVGRAIKRAIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQP 114

Query: 422 IATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                       D    W+ M++  + GL R+IGVSNF   ++  L+ +  I P  NQIE
Sbjct: 115 FG----------DVHCAWKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVHHEIVPAVNQIE 164


>UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3;
           Actinobacteria (class)|Rep: 2,5-didehydrogluconate
           reductase - Arthrobacter sp. (strain FB24)
          Length = 276

 Score =  126 bits (304), Expect = 4e-28
 Identities = 76/178 (42%), Positives = 105/178 (58%)
 Frame = +2

Query: 68  APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247
           +P I+LNDG+ IP + LGT        D   +V  AV  A+E GYRHIDTA  Y +E+ V
Sbjct: 4   SPVIELNDGHRIPQIGLGTW-----PLDD-HQVAAAVVNAVEGGYRHIDTAVKYGNEKGV 57

Query: 248 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427
           G GI    ++GL  R ELF+TTKL  +   +D+ V  L  SLK+LGLDY+DL LIH+P+ 
Sbjct: 58  GNGIR---SSGL-DRSELFITTKLDGEFQGQDRAVAGLDGSLKRLGLDYVDLLLIHWPL- 112

Query: 428 TKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                 P   +++ TW+  +  +  G  RSIGVSNF    + RL++   + P  NQI+
Sbjct: 113 ------PRRDEFISTWKTFERLQADGKVRSIGVSNFKPAHLERLMAACDVVPAVNQIQ 164


>UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep:
           Aldose reductase - Magnaporthe grisea (Rice blast
           fungus) (Pyricularia grisea)
          Length = 312

 Score =  126 bits (303), Expect = 5e-28
 Identities = 75/187 (40%), Positives = 111/187 (59%), Gaps = 14/187 (7%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
           LN G  IP   LGT +G          +++AV  AI++GYR ID A VY +EE+VGQGI 
Sbjct: 8   LNTGAKIPAFGLGTWQGDK------GVIKEAVLTAIKSGYRLIDGAYVYGNEEEVGQGIR 61

Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 436
           EAI++G+V RE+LFV +K W     R ++   L +SLK LGLDY+DLYL+H+PI   P  
Sbjct: 62  EAISSGIVKREDLFVVSKCWATYTTRCEL--GLDQSLKLLGLDYVDLYLVHWPILMNPEG 119

Query: 437 ---------DDSPDNI---DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 580
                    D S D I   ++++TW+ M+     G  +++GVSN++   + +L+ ++   
Sbjct: 120 NDEKFPKHADGSRDIIHTHNHVDTWKLMEKLPATGKTKAVGVSNYSKAWLEQLLPHATTV 179

Query: 581 PGXNQIE 601
           P  NQ+E
Sbjct: 180 PAVNQVE 186


>UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain
           CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep:
           Yarrowia lipolytica chromosome B of strain CLIB122 of
           Yarrowia lipolytica - Yarrowia lipolytica (Candida
           lipolytica)
          Length = 337

 Score =  125 bits (302), Expect = 7e-28
 Identities = 78/188 (41%), Positives = 111/188 (59%), Gaps = 15/188 (7%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAI-EAGYRHIDTAAVYQDEEQVGQGI 259
           LN+G TIP + LGT + T       +EV  AV  A+ E GYRHIDTA  Y++E+ VG GI
Sbjct: 36  LNNGKTIPAIGLGTWKSTT------EEVAGAVECALTEGGYRHIDTAFNYRNEDAVGLGI 89

Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 439
             A+  G V RE++FVTTK+W   H  D+V   L  SL++LGLDY+D+ LIH+P+   P+
Sbjct: 90  KRAMEKG-VKREDIFVTTKIWVTYH--DRVEENLDMSLERLGLDYVDMLLIHWPVPLNPN 146

Query: 440 DS-------PD---NID----YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 577
            +       PD   +ID      +TW+ M+   + G  +SIGVSNF+   +  L+  + +
Sbjct: 147 GNDPVYPLRPDGSRDIDESGSQPKTWKQMEAVLKTGKTKSIGVSNFSIPYLEELLKEAEV 206

Query: 578 RPGXNQIE 601
            P  NQ+E
Sbjct: 207 VPAVNQVE 214


>UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2;
           Actinomycetales|Rep: Putative oxidoreductase -
           Streptomyces coelicolor
          Length = 277

 Score =  125 bits (301), Expect = 9e-28
 Identities = 77/182 (42%), Positives = 107/182 (58%)
 Frame = +2

Query: 56  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235
           M+ + P I LN+G  +P +    G G  +  D  D+ + AV  A+EAGYR IDTAA+Y +
Sbjct: 1   MSSKVPPIILNNGVEMPQL----GFGVWQVPD--DDAQTAVALALEAGYRSIDTAAIYGN 54

Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415
           EE  G+ IA   A+GL  RE+LFVTTKLWN     D  + A   S+ KLGL+Y+DLYLIH
Sbjct: 55  EEGTGRAIA---ASGLA-REDLFVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYLDLYLIH 110

Query: 416 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQ 595
           +P+  K         Y++T++  +     G  R+IGVSNF    + RL + + + P  NQ
Sbjct: 111 WPMPAKE-------RYVDTYKAFEKLLADGRVRAIGVSNFLPEHLERLTAETSVIPAVNQ 163

Query: 596 IE 601
           IE
Sbjct: 164 IE 165


>UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep:
           Oxidoreductase - Lactobacillus acidophilus
          Length = 285

 Score =  125 bits (301), Expect = 9e-28
 Identities = 68/172 (39%), Positives = 102/172 (59%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
           LN+G  IPI+  GT      ++   +   ++V  A+  GYRHIDTA+ Y +E+ VG+ I 
Sbjct: 12  LNNGVKIPIIGFGTW-----QTPDGEVAEESVLAALNCGYRHIDTASAYGNEDSVGRAIQ 66

Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 442
           ++  N    R ELF+TTKLWN  H  ++   A+ +SL  L LDY+D+YLIH+P  +   D
Sbjct: 67  KSGIN----RHELFITTKLWNSDHGYEKTKKAIDQSLLDLKLDYLDMYLIHWPNPSSMRD 122

Query: 443 SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598
               I+  E+W+ M++A + G  R+IGVSNF    +  L+  + I+P  NQI
Sbjct: 123 HWAEIN-AESWRAMEEAVRAGKIRAIGVSNFRKHHLDALMETAEIKPVVNQI 173


>UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family
           protein; n=2; Tetrahymena thermophila SB210|Rep:
           Oxidoreductase, aldo/keto reductase family protein -
           Tetrahymena thermophila SB210
          Length = 332

 Score =  124 bits (300), Expect = 1e-27
 Identities = 64/175 (36%), Positives = 109/175 (62%), Gaps = 1/175 (0%)
 Frame = +2

Query: 80  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259
           +LN+G  +P+V LGT    +KE     E+   +  A++AGYRHIDTA  YQ+E  +G+ +
Sbjct: 9   KLNNGQIMPLVGLGTYLLNSKE-----EMTNLLRTALDAGYRHIDTAVNYQNEAMIGESL 63

Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA-TKP 436
                 G  +R++LF+ +K++ +K     ++ ++++SLK+L LDY+DLY +HFP+     
Sbjct: 64  KTIFKEGKYSRKDLFIVSKVFPNKGI--NMLESVKKSLKELQLDYVDLYYLHFPLGFLSE 121

Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
            +   ++     W  +++A +LGLA+SIGVSNFN   +  L+S + ++P  NQ+E
Sbjct: 122 KEEFVHLPVHVAWAQLEEAHRLGLAKSIGVSNFNVMALADLLSYAKVKPVSNQVE 176


>UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14;
           Dikarya|Rep: Aldo-keto reductase, putative -
           Cryptococcus neoformans (Filobasidiella neoformans)
          Length = 353

 Score =  124 bits (300), Expect = 1e-27
 Identities = 77/205 (37%), Positives = 116/205 (56%), Gaps = 14/205 (6%)
 Frame = +2

Query: 29  TLTCLLNAAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRH 208
           T+  + N+ +       +LN G +IP + LGT +  A       EVRQAV  A++AGYRH
Sbjct: 23  TILPIFNSLIMSAPTSFKLNTGASIPAIGLGTWQAKA------GEVRQAVAHALKAGYRH 76

Query: 209 IDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGL 388
           ID A  YQ+E++VG GI +   +G V R E+F+T+K+W+  H  D+V   L  +LK L  
Sbjct: 77  IDGALCYQNEDEVGLGIKD---SG-VPRSEIFLTSKVWSSYH--DRVEECLDTTLKSLQT 130

Query: 389 DYIDLYLIHFPIATKPDDS-------PD---NIDY----LETWQGMQDARQLGLARSIGV 526
           DY+DLYLIH+P+   P+ +       PD   N+D+     +TW  M+D  + G A++IG+
Sbjct: 131 DYLDLYLIHWPVRLAPNGTHPLFPVKPDGSRNLDWDWDQAKTWAQMEDVLKKGKAKAIGL 190

Query: 527 SNFNATQITRLVSNSYIRPGXNQIE 601
           SN     I  ++    + P  NQ+E
Sbjct: 191 SNAGIPIIEHIIKTGKVTPAVNQVE 215


>UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose
           reductase - Hordeum vulgare (Barley)
          Length = 320

 Score =  124 bits (300), Expect = 1e-27
 Identities = 73/180 (40%), Positives = 112/180 (62%), Gaps = 7/180 (3%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
           L  G+ +P V LGT R     SD+   VR A+    EAGYRH+DTAA Y  E++VG+G+ 
Sbjct: 18  LKSGHAMPAVGLGTWRAG---SDTAHSVRTAI---TEAGYRHVDTAAEYGVEKEVGKGLK 71

Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK--- 433
            A+  G + R++LFVT+K+W    A ++V PAL+ +LK L LDYIDLY IH+P   K   
Sbjct: 72  AAMEAG-IDRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLKDGA 130

Query: 434 --PDDSPDNIDY-LE-TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
             P ++ + +++ +E  W+ M++  + GL + IGV N+  T++ RL+ ++ I P   Q+E
Sbjct: 131 HMPPEAGEVLEFDMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAKIPPAVCQME 190


>UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           GA15457-PA - Nasonia vitripennis
          Length = 388

 Score =  124 bits (299), Expect = 2e-27
 Identities = 76/205 (37%), Positives = 118/205 (57%), Gaps = 12/205 (5%)
 Frame = +2

Query: 23  IITLTCLLNAAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGY 202
           ++ L  +L  A AV+   ++L+ G+ IP V LGT   T K    +DE+  A+  A+E GY
Sbjct: 10  LVVLAVVLPGAQAVEK--LKLSSGHEIPAVGLGTS--TIK----LDEMDNAISSALENGY 61

Query: 203 RHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKL 382
           RHIDTA  Y +E  +G+ + +    G   RE++F+T+KL +  +    V   L+ SLK L
Sbjct: 62  RHIDTAFSYDNEAAIGKILKKWFDKG-GKREDIFITSKLPSQGNRPQSVETYLKRSLKDL 120

Query: 383 GLDYIDLYLIHFPIATKP------------DDSPDNIDYLETWQGMQDARQLGLARSIGV 526
           GLDY+D+YLIH P A K             +D  D++D+   W+ M+   + G A+SIG+
Sbjct: 121 GLDYVDMYLIHTPFAVKEGENLSSKQDKDGNDLFDDVDHKALWKAMERQVKEGRAKSIGL 180

Query: 527 SNFNATQITRLVSNSYIRPGXNQIE 601
           SNFN +Q+  + +N+ I+P   Q+E
Sbjct: 181 SNFNQSQVLNIYNNAEIKPSNLQVE 205


>UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5;
           Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative
           - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 /
           NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 /
           DSM 3700 / NRRL 181))
          Length = 321

 Score =  124 bits (299), Expect = 2e-27
 Identities = 75/193 (38%), Positives = 101/193 (52%), Gaps = 16/193 (8%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P  +LN G  +P+V  G  +         D++    Y AI+AGYR  D A  Y +E + G
Sbjct: 4   PSTKLNSGYDMPLVGFGLWK--VNNETCADQI----YHAIKAGYRLFDGACDYGNEVEAG 57

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430
           +G+A AI  G+V RE+LF+ +KLWN  H  D+V P  ++ L   GLDY DL+++HFPIA 
Sbjct: 58  KGVARAIQEGIVKREDLFIVSKLWNSFHDGDRVEPICRKQLADWGLDYFDLFIVHFPIAL 117

Query: 431 KPDDSP----------------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 562
           K  D                   N    ETW  M+      LARSIGVSNF+A  +  L+
Sbjct: 118 KYVDPAVRYPPGWLSENNKLEFSNASIQETWTAMESLVDKKLARSIGVSNFSAQLLMDLL 177

Query: 563 SNSYIRPGXNQIE 601
             + IRP   QIE
Sbjct: 178 RYARIRPATLQIE 190


>UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2;
           Bacteria|Rep: 2,5-didehydrogluconate reductase -
           Exiguobacterium sibiricum 255-15
          Length = 274

 Score =  124 bits (298), Expect = 2e-27
 Identities = 67/175 (38%), Positives = 107/175 (61%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           + LN+G  +P +    G G  K  +   EV +AV  A+  GYR IDTA +Y++E  VG+ 
Sbjct: 4   VTLNNGLVMPQL----GYGVFKVPEQ--EVYEAVREALRVGYRSIDTAMIYENEAGVGR- 56

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
              A+ +  + RE++F+TTK+WN     ++ + A + SL+KLG+DY+DLYLIH+P+    
Sbjct: 57  ---ALKDSGIPREDIFLTTKVWNKDQGYERTLAAFETSLQKLGVDYVDLYLIHWPM---- 109

Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
              PD   Y++TW+ ++   + G A++IGVSNF+   +TR++    + P  NQIE
Sbjct: 110 ---PDEDLYMDTWRALEQLYRDGKAKAIGVSNFHIPHLTRVLEEGTVVPAVNQIE 161


>UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep:
           CG2767-PA - Drosophila melanogaster (Fruit fly)
          Length = 329

 Score =  124 bits (298), Expect = 2e-27
 Identities = 71/193 (36%), Positives = 107/193 (55%), Gaps = 13/193 (6%)
 Frame = +2

Query: 62  VQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEE 241
           V    +  N+G  +P++ +GT +       S +E+  A+  A+EAGYRHIDTA VY +E+
Sbjct: 2   VNTKFLTFNNGEKMPVIGIGTWQA------SDEEIETAIDAALEAGYRHIDTAPVYGNEK 55

Query: 242 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 421
            +G+ +   +  G V REELF+ TK+    +   +V P +++SL+ L LDY+DLYL+H P
Sbjct: 56  AIGRVLKRWLDAGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTP 115

Query: 422 IATK-PDDSPDNID------------YLETWQGMQDARQLGLARSIGVSNFNATQITRLV 562
                 +D    +D            +   W  M+   + GL +SIGVSNF+  Q+ RL+
Sbjct: 116 FTININEDGSFKLDKEGLMEVDVTTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLL 175

Query: 563 SNSYIRPGXNQIE 601
            N  IRP  NQIE
Sbjct: 176 KNCKIRPANNQIE 188


>UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep:
           Oxidoreductase - Xanthomonas campestris pv. campestris
           (strain 8004)
          Length = 267

 Score =  123 bits (297), Expect = 3e-27
 Identities = 74/146 (50%), Positives = 94/146 (64%)
 Frame = +2

Query: 98  TIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIAN 277
           T+P   LGT R   K+   ID VR A    +  GYR IDTA +Y +E QVGQ IA+A   
Sbjct: 2   TVPAFGLGTFR--LKDQVVIDSVRNA----LALGYRAIDTAQIYDNEAQVGQAIADA--- 52

Query: 278 GLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNI 457
           G V R++LFVTTK+W D+ +RD + P+LQESL+KLG DY+DL LIH+P    P D     
Sbjct: 53  G-VPRDQLFVTTKIWVDRFSRDTLQPSLQESLRKLGTDYVDLTLIHWP---SPKDQVPMR 108

Query: 458 DYLETWQGMQDARQLGLARSIGVSNF 535
           +YLE    + DA+  GL R+IGVSNF
Sbjct: 109 EYLE---ALADAKAQGLTRAIGVSNF 131


>UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae
           str. PEST
          Length = 310

 Score =  123 bits (296), Expect = 4e-27
 Identities = 73/188 (38%), Positives = 106/188 (56%), Gaps = 12/188 (6%)
 Frame = +2

Query: 74  CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
           CI L+D ++I +  +G G  +   +D     ++A+  AI+ GYR  DTA  Y +E  VG+
Sbjct: 6   CINLSDQHSIALPTIGLGTYSILGADG----KEAIRTAIDVGYRMFDTAVAYGNEAIVGE 61

Query: 254 GIAEAIAN-GLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA- 427
            I E I     +TR++ F+ +KL    H +D V    + +L +LG+DY+DLYL+H P+A 
Sbjct: 62  AIREKIRECNNLTRDDFFIISKLSGSYHRQDLVEKCCRMTLDRLGMDYVDLYLMHTPVAL 121

Query: 428 ----------TKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 577
                     TK +   D+I   E W G++   Q GL RSIGVSNFN  QI  L+S++ I
Sbjct: 122 QSEKKCARNGTKLNAIDDSIAPTEAWIGLEQCYQEGLCRSIGVSNFNEHQINALLSDASI 181

Query: 578 RPGXNQIE 601
            P  NQIE
Sbjct: 182 VPAVNQIE 189


>UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6;
           Bacteria|Rep: 2,5-didehydrogluconate reductase -
           Opitutaceae bacterium TAV2
          Length = 334

 Score =  122 bits (294), Expect = 7e-27
 Identities = 74/177 (41%), Positives = 103/177 (58%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P + L+DG +IP + LG  +      D      QA   A  AGYR IDTA +Y +EE VG
Sbjct: 60  PTLPLSDGTSIPQLGLGVWQ---MPDDGAGVPIQA---AFNAGYRAIDTAPIYGNEEGVG 113

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430
           + I    A+GL  R+EL++TTK+WN     D  + A++ESL +L L+Y+DLYLIH+P+  
Sbjct: 114 RAIR---ASGL-PRKELYITTKVWNSAQGYDSTLRAVRESLGRLQLEYVDLYLIHWPV-- 167

Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                P    Y++TW+ +   +  GLARSIGVSNF    + RL   + I P  NQ+E
Sbjct: 168 -----PKIDRYVDTWKALAKIKADGLARSIGVSNFTPVYLQRLFDETGIVPVVNQVE 219


>UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1;
           Arabidopsis thaliana|Rep: Uncharacterized protein
           At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress)
          Length = 283

 Score =  122 bits (294), Expect = 7e-27
 Identities = 71/188 (37%), Positives = 103/188 (54%), Gaps = 6/188 (3%)
 Frame = +2

Query: 56  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235
           MA      +LN G   P V LGT +       S   V  AV  A++ GYRHID A +Y +
Sbjct: 1   MANAITFFKLNTGAKFPSVGLGTWQA------SPGLVGDAVAAAVKIGYRHIDCAQIYGN 54

Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415
           E+++G  + +   + +V RE+LF+T+KLW   H    V  AL  +LK L L+Y+DLYLIH
Sbjct: 55  EKEIGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIH 114

Query: 416 FPIATKPDD---SPDN---IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 577
           +P   K       P+N   +D   TW+ M+     G AR+IGVSNF+  ++  L+  + +
Sbjct: 115 WPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARV 174

Query: 578 RPGXNQIE 601
            P  NQ+E
Sbjct: 175 PPAVNQVE 182


>UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32;
           Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 315

 Score =  122 bits (294), Expect = 7e-27
 Identities = 71/188 (37%), Positives = 103/188 (54%), Gaps = 6/188 (3%)
 Frame = +2

Query: 56  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235
           MA      +LN G   P V LGT +       S   V  AV  A++ GYRHID A +Y +
Sbjct: 1   MANAITFFKLNTGAKFPSVGLGTWQA------SPGLVGDAVAAAVKIGYRHIDCAQIYGN 54

Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415
           E+++G  + +   + +V RE+LF+T+KLW   H    V  AL  +LK L L+Y+DLYLIH
Sbjct: 55  EKEIGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIH 114

Query: 416 FPIATKPDD---SPDN---IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 577
           +P   K       P+N   +D   TW+ M+     G AR+IGVSNF+  ++  L+  + +
Sbjct: 115 WPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARV 174

Query: 578 RPGXNQIE 601
            P  NQ+E
Sbjct: 175 PPAVNQVE 182


>UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep:
           Lin2739 protein - Listeria innocua
          Length = 283

 Score =  121 bits (292), Expect = 1e-26
 Identities = 75/175 (42%), Positives = 101/175 (57%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           ++LN+G  +PI+  GT + T        E  QAV  AI AGYRHIDTA  Y +EE VG+G
Sbjct: 4   VKLNNGIEVPILGFGTYQIT-----DAGEAEQAVKEAIAAGYRHIDTAQSYMNEEAVGRG 58

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
           IA   A+G V R+ELF+TTK+W +  +   V+ +   SLK+LGLDYIDL LIH P     
Sbjct: 59  IA---ASG-VDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYIDLLLIHQPYN--- 111

Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                  D    W  M++ +  G  ++IGVSNF   ++  L + + I P  NQIE
Sbjct: 112 -------DVYGAWMAMEELQAQGKIKAIGVSNFGVDRVVDLAAFNDITPQVNQIE 159


>UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2;
           Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid
           reductase - Tropheryma whipplei (strain Twist)
           (Whipple's bacillus)
          Length = 283

 Score =  121 bits (292), Expect = 1e-26
 Identities = 72/177 (40%), Positives = 101/177 (57%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P + L DG +IP   LGT      E+ S+      V  AIE GYRHIDTA++Y +E +VG
Sbjct: 10  PSVLLGDGVSIPQFGLGTYELPPNEASSV------VQSAIELGYRHIDTASLYANEREVG 63

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430
           +    AIA+  + REE FVTTKLWN    + +   A + SL  L LDY+DLYLIH+P   
Sbjct: 64  R----AIASSGIKREEFFVTTKLWNSDQPKPR--EAFERSLDLLSLDYVDLYLIHWP--- 114

Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                P +  Y+  W+ + + ++ G A+S+GVSNF +  I ++    +  P  NQIE
Sbjct: 115 ----CPPSELYINVWEVLLELKESGRAKSVGVSNFLSEHIDKIKEAGFPLPSVNQIE 167


>UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5;
           Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas
           putida
          Length = 296

 Score =  121 bits (292), Expect = 1e-26
 Identities = 75/182 (41%), Positives = 109/182 (59%)
 Frame = +2

Query: 56  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235
           MA ++P I LN+G  +P + LG    +A+E+ S      A+  AI +GYR IDTA  Y +
Sbjct: 1   MAGKSPLINLNNGVKMPALGLGVFAASAEETAS------AIASAISSGYRLIDTARSYNN 54

Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415
           E QVG+GI     N  V R E+FVTTKL+N  +  ++ + A  ESL +LGLDY+DLYL+H
Sbjct: 55  EAQVGEGIR----NSGVDRAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLH 110

Query: 416 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQ 595
           +P  TK  ++      +++W+  +     G AR+IGV NF   Q+  L++ S + P  NQ
Sbjct: 111 WP--TKDWNAT-----IQSWKAAEKILGDGRARAIGVCNFLEDQLDELIAASDVVPAVNQ 163

Query: 596 IE 601
           IE
Sbjct: 164 IE 165


>UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3;
           Actinomycetales|Rep: 2,5-didehydrogluconate reductase -
           Kineococcus radiotolerans SRS30216
          Length = 289

 Score =  120 bits (289), Expect = 3e-26
 Identities = 77/181 (42%), Positives = 106/181 (58%)
 Frame = +2

Query: 59  AVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDE 238
           A+  P I LNDG  IP   LG G    +  D+     QAV  A++ GYRHIDTA +Y +E
Sbjct: 9   AMTVPTILLNDGREIP--QLGFGVFQIEPGDTA----QAVKTALDLGYRHIDTAQMYGNE 62

Query: 239 EQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 418
            +V QGIA++   G V R+E++VT+KL N  H  D    A+ +S++KL    IDLYLIH+
Sbjct: 63  AEVAQGIADS---G-VPRDEIWVTSKLNNGFHEPDAARKAVDDSVEKLR-GPIDLYLIHW 117

Query: 419 PIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598
           P+ T         D++ TW+ +++AR  G  RSIGVSNF    + RL   + + P  NQI
Sbjct: 118 PLPTLYGG-----DFVSTWKVLEEARAAGKLRSIGVSNFQVNHLQRLAQEATVVPAVNQI 172

Query: 599 E 601
           E
Sbjct: 173 E 173


>UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452
           protein; n=6; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to LOC553452 protein -
           Strongylocentrotus purpuratus
          Length = 321

 Score =  120 bits (288), Expect = 4e-26
 Identities = 72/182 (39%), Positives = 102/182 (56%), Gaps = 13/182 (7%)
 Frame = +2

Query: 56  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235
           MA     I L  G  +P++  GT +         +EV + +  AI+ GYRHID A++Y +
Sbjct: 1   MASSNTHIVLPGGRKLPLLGFGTWQIKP------EEVGRVIETAIDCGYRHIDEASLYGN 54

Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLW-NDKHARDQVVPALQESLKKLGLDYIDLYLI 412
           E+ VG GI   I +G + RE+LFVT+KLW  D H   +V P+ ++SL  LGL Y+DL+LI
Sbjct: 55  EKGVGDGIKAKIDDGTIKREDLFVTSKLWVTDSHP-SRVEPSCRQSLSDLGLAYLDLFLI 113

Query: 413 HFPIATKPDDSP------------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITR 556
           H P +      P            D IDY++TW+ M+     GL R+IGVSNF   QI R
Sbjct: 114 HCPTSAVGGKGPFPMDDNGLFIGDDTIDYVDTWRIMESLVDKGLVRAIGVSNFTVAQIQR 173

Query: 557 LV 562
           ++
Sbjct: 174 VL 175


>UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep:
           Lmo2592 protein - Listeria monocytogenes
          Length = 283

 Score =  119 bits (287), Expect = 5e-26
 Identities = 74/175 (42%), Positives = 105/175 (60%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           ++LN+G  +PI+    G GT + +D+  E   AV  AI+AGYRHIDTA  Y +EE VG+G
Sbjct: 4   VKLNNGVEVPIL----GFGTYQITDAA-EAEHAVKDAIKAGYRHIDTAQSYMNEEAVGRG 58

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
           IA   A+G V R+ELF+TTK+W +  +   V+ +   SLK+LGLDY+DL LIH P     
Sbjct: 59  IA---ASG-VDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYVDLLLIHQPFN--- 111

Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                  D    W  M++ +  G  R+IGVSNF+  ++  L + + + P  NQIE
Sbjct: 112 -------DVYGAWIAMEELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQIE 159


>UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;
           n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
           A - Escherichia coli (strain UTI89 / UPEC)
          Length = 294

 Score =  119 bits (287), Expect = 5e-26
 Identities = 66/160 (41%), Positives = 93/160 (58%), Gaps = 1/160 (0%)
 Frame = +2

Query: 125 GRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 304
           G G  + +D  D  +Q+V  AI  GYR IDTAAVY +E+ VG+ + EAI+ GL TREELF
Sbjct: 21  GFGVFQVTDK-DVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGEAVREAISEGLCTREELF 79

Query: 305 VTTKLW-NDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQG 481
           +T+KLW  D   +D     ++ SLKK GL+Y DLYL+H  +           DY   W+ 
Sbjct: 80  ITSKLWVQDMLNQDIAAAGIEASLKKSGLEYFDLYLLHQAMR----------DYFSAWRA 129

Query: 482 MQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
           ++DA + G  ++IGVSNF    +        ++P  NQ+E
Sbjct: 130 LEDAYEEGKLKAIGVSNFYPHVLANFCETVRVKPMVNQVE 169


>UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium
           SCB49|Rep: ARA1 - unidentified eubacterium SCB49
          Length = 280

 Score =  119 bits (287), Expect = 5e-26
 Identities = 64/174 (36%), Positives = 106/174 (60%)
 Frame = +2

Query: 80  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259
           +LN+   IP +  GT + T     +I+ ++ A    I+AGY+HID AA+Y++E+ VG GI
Sbjct: 6   KLNNNINIPAIGFGTWQ-TPDGQTAINAIKTA----IDAGYKHIDAAAIYKNEKGVGLGI 60

Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 439
            EA     + R++LFVT+K+WN++   +  + A   ++  L LDY+DLYLIH+P A    
Sbjct: 61  KEAN----IDRKDLFVTSKVWNEQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAAHQF 116

Query: 440 DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
           ++   ++  +TW  M+   + G  +++GVSNF    +T L+ ++ I+P  NQIE
Sbjct: 117 ENWKQLNN-DTWSAMEKLYKDGKIKALGVSNFMEHHLTPLLQHATIKPTVNQIE 169


>UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 275

 Score =  119 bits (287), Expect = 5e-26
 Identities = 71/173 (41%), Positives = 99/173 (57%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
           L+DG  IP   LG      K +      +QAV WA+E GYR IDTAA Y +E++VG    
Sbjct: 9   LSDGYKIPRFGLGLYDLDEKHT------KQAVLWALENGYRMIDTAASYNNEKRVG---- 58

Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 442
           EA+    V R E+++ TK+++  H  ++ + A   SL  LG+DY+DLYLIHFP+      
Sbjct: 59  EALRESAVPRSEVYLVTKVYHTDHGYEKTMKAYDRSLSALGVDYVDLYLIHFPV------ 112

Query: 443 SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
            P  +  + +W+ M + +  GL RSIGVSNFN   +  L  +S I P  NQIE
Sbjct: 113 -PAGV--VGSWEAMAELQGKGLTRSIGVSNFNIHHLEALQKHSVIPPVVNQIE 162


>UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep:
           Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 289

 Score =  119 bits (286), Expect = 6e-26
 Identities = 69/181 (38%), Positives = 101/181 (55%)
 Frame = +2

Query: 59  AVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDE 238
           A+  P + L++G  IPI+ LGT        +++      +Y   E G RHIDTA  Y  E
Sbjct: 10  ALSCPAVPLHNGLNIPILGLGTSHYGGYSHEAV------LYALQECGIRHIDTAKRYGCE 63

Query: 239 EQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 418
           E +G+ + E+   G V REEL+VTTKLW   +       A ++S  +LG+DY+DLYL+H+
Sbjct: 64  EALGKAVTES---G-VQREELWVTTKLWPGDYGYQSTKQACRDSRARLGVDYLDLYLMHW 119

Query: 419 PIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598
           P +  P  S   +  LETW+ +++    GL R+IGVSNF    +  L  +  I P  NQ+
Sbjct: 120 PDSMVPGRSSQEV-RLETWRALEELYDEGLCRAIGVSNFLIPHLNELKDSGGIVPHVNQV 178

Query: 599 E 601
           E
Sbjct: 179 E 179


>UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4;
           Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia
           sp. (strain CCS1)
          Length = 276

 Score =  119 bits (286), Expect = 6e-26
 Identities = 71/177 (40%), Positives = 102/177 (57%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P I+ +DG  IP V  G  +         D   + V  AIE GYR ID A +Y +E  +G
Sbjct: 5   PVIKFHDGAQIPQVGFGIWQVPQ------DIAGETVRSAIEIGYRMIDGAYLYMNEAGLG 58

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430
           +G+    A+GL  R+E+FVTTK+WN++    +   +++ SLK +G++ +DL LIH+P+  
Sbjct: 59  EGLR---ASGL-PRDEVFVTTKVWNNEQGAAKARASVERSLKTIGVEQLDLVLIHWPV-- 112

Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                P    YLETW+  QD R  GL RSIG SNFNA  + R+++ +   P  NQIE
Sbjct: 113 -----PSQDLYLETWKAFQDMRDEGLMRSIGTSNFNADHLERIIAETGEAPVLNQIE 164


>UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 339

 Score =  119 bits (286), Expect = 6e-26
 Identities = 65/194 (33%), Positives = 110/194 (56%), Gaps = 16/194 (8%)
 Frame = +2

Query: 68  APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247
           A  + LN G  +P++  GT +    ++ + + VR A    +EAGYRHID+A  ++++E+V
Sbjct: 4   ADTVTLNSGYEMPVIGYGTWQ--LPKNLAAERVRDA----LEAGYRHIDSALSFKNQEEV 57

Query: 248 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427
             GI +      V REELF+++K+WN  H+R++ +  + E L+     Y+DL +IH+P  
Sbjct: 58  AAGIKDWCKIRKVRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIHWPFG 117

Query: 428 TKPDDSP----------------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRL 559
              D+ P                 ++DYLETW+ ++DA + G  RSIG++NFN  Q+ ++
Sbjct: 118 WAEDEPPGERGLWPRGANGKMRYSDVDYLETWKALEDAHRSGKIRSIGLANFNIGQVEQV 177

Query: 560 VSNSYIRPGXNQIE 601
            +   I+P   Q+E
Sbjct: 178 WTKGLIKPAVLQVE 191


>UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep:
           Aldehyde reductase - Acidobacteria bacterium (strain
           Ellin345)
          Length = 313

 Score =  118 bits (285), Expect = 8e-26
 Identities = 66/177 (37%), Positives = 97/177 (54%), Gaps = 12/177 (6%)
 Frame = +2

Query: 107 IVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLV 286
           I ALG G   A  + +I   R A    + AG+RH D A  Y++E +VG+ +    A G +
Sbjct: 20  IPALGFGTLIADPALTITATRDA----LAAGFRHFDCAERYRNEREVGEALRAGRAAGNI 75

Query: 287 TREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPD----- 451
            REE+FVTTKLWN  H  ++V PA + SL +LGLDY+DLYLIH P A +P D  D     
Sbjct: 76  AREEIFVTTKLWNTNHRPERVEPAFEASLDRLGLDYLDLYLIHTPFAFQPGDEQDPRDQN 135

Query: 452 -------NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                   +   ETW  +++    G  R+IG+S+ +  ++  +   + I+P   Q+E
Sbjct: 136 GSVIYDEGVTLRETWSALENLVDRGRCRAIGLSDISMDRLAPIYEAARIKPAVVQVE 192


>UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8;
           Saccharomycetaceae|Rep: Glycerol dehydrogenase -
           Zygosaccharomyces rouxii (Candida mogii)
          Length = 310

 Score =  118 bits (285), Expect = 8e-26
 Identities = 78/195 (40%), Positives = 114/195 (58%), Gaps = 20/195 (10%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           ++LN G TIP V LGT R  +KE++      +AV  A++AGYRHID AAVY +E +VG+ 
Sbjct: 11  LKLNTGQTIPQVGLGTWR--SKENEGY----KAVIEALKAGYRHIDGAAVYGNEGEVGK- 63

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI---- 424
              AI +  V R E+F+TTKLW       Q   AL +SL++LGLDY+ LYL+H+P+    
Sbjct: 64  ---AIQDSGVPRNEIFLTTKLWCTHQRNPQ--EALDQSLQRLGLDYVGLYLVHWPVPLRT 118

Query: 425 -----------ATKPDDSPD---NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 562
                      A KPD S D     ++++TW+ MQ   + G  ++IGVSNF+   +  L+
Sbjct: 119 ENIKDGNLFQFAEKPDGSKDVDLEWNFIKTWELMQKLLESGKTKAIGVSNFSVNNLKDLL 178

Query: 563 S--NSYIRPGXNQIE 601
           +   + + P  NQ+E
Sbjct: 179 AAPTTKVTPAVNQVE 193


>UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto
           reductase family - Enterococcus faecalis (Streptococcus
           faecalis)
          Length = 279

 Score =  118 bits (284), Expect = 1e-25
 Identities = 69/178 (38%), Positives = 99/178 (55%)
 Frame = +2

Query: 68  APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247
           A  + LN+G  IP    G G G  +  D  +E  + V   I  GYR IDTA +Y +E   
Sbjct: 6   ADTVTLNNGTKIP----GMGLGVFQIPD--EETAKVVEEGIINGYRLIDTAQIYGNESGT 59

Query: 248 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427
           G GI   +A   + RE+LFVT+K+WN   + D+ + A  +SL++LGLDY+DLYLIH+   
Sbjct: 60  GAGIKAGLAATGLNREDLFVTSKVWNAHISYDETIQAFNDSLERLGLDYLDLYLIHW--- 116

Query: 428 TKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                 P N  Y E+WQ ++     G  ++IGVSNF    +  L+S + + P  NQ+E
Sbjct: 117 ------PGNNSYKESWQALETLYAEGKVKAIGVSNFQVHHLEDLLSYAKVVPVINQVE 168


>UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep:
           Benzil reductase - Bacillus subtilis
          Length = 276

 Score =  118 bits (284), Expect = 1e-25
 Identities = 68/175 (38%), Positives = 108/175 (61%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           ++L++G  +P   LG  +      ++ +E  ++V  AI+ GYR IDTAA+Y++EE VG G
Sbjct: 9   VKLHNGVEMPWFGLGVFK-----VENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIG 63

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
           I E+   G V REELF+T+K+WN+    +  + A ++SL++L LDY+DLYLIH+P   K 
Sbjct: 64  IKES---G-VAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWPGKDK- 118

Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                   Y +TW+ ++   + G  R+IGVSNF    +  L+ ++ I+P  NQ+E
Sbjct: 119 --------YKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQVE 165


>UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1;
           Erythrobacter sp. SD-21|Rep: Putative oxidoreductase
           protein - Erythrobacter sp. SD-21
          Length = 272

 Score =  118 bits (283), Expect = 1e-25
 Identities = 65/177 (36%), Positives = 102/177 (57%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P + LNDG  IP   LG G    +E D+     QAV  AI+ GY  IDTAA+Y +E+ VG
Sbjct: 5   PTLNLNDGRQIP--QLGFGTWQMEEEDA----PQAVSTAIDVGYWLIDTAAIYGNEKGVG 58

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430
           +G+ E          ++F+ TK+WND    D+ + A ++ L++LG +++D+ LIH+P   
Sbjct: 59  KGVGEW--------SDIFLQTKIWNDSQGYDRTLRAAEKCLERLGREHVDMLLIHWP--- 107

Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                P+   +++TW+ + + R  G A+SIGVSNF    + R++  + + P  NQIE
Sbjct: 108 ----CPEKDQFVDTWKALIELRDAGKAKSIGVSNFREEDLKRIIDETGVTPALNQIE 160


>UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6;
           Pezizomycotina|Rep: Aldo/keto reductase family proteins
           - Aspergillus oryzae
          Length = 294

 Score =  118 bits (283), Expect = 1e-25
 Identities = 71/180 (39%), Positives = 107/180 (59%), Gaps = 3/180 (1%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKES--DSID-EVRQAVYWAIEAGYRHIDTAAVYQDEE 241
           P ++LND  +IPI+  GTG    K++  DS++ E+ +A+  AI  GYRH+D A VY  E 
Sbjct: 10  PRVKLNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGAEVYGTEA 69

Query: 242 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 421
           ++G  I E+   G + REELFVTTK+  +      +  A+ +SL+KL L+Y+DLYLIH P
Sbjct: 70  ELGVAIKES---G-IPREELFVTTKVITNIA---DIPSAIDQSLRKLQLNYVDLYLIHSP 122

Query: 422 IATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
              K D      +  + W  M+  +Q G A++IGVSN++ + +   +  + I P  NQIE
Sbjct: 123 FFAKSDG-----ELQQAWAAMEKVQQAGKAKAIGVSNYHQSHLEATLKTAVIAPVINQIE 177


>UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3;
           Sclerotiniaceae|Rep: Putative uncharacterized protein -
           Botryotinia fuckeliana B05.10
          Length = 360

 Score =  118 bits (283), Expect = 1e-25
 Identities = 66/160 (41%), Positives = 99/160 (61%), Gaps = 1/160 (0%)
 Frame = +2

Query: 125 GRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 304
           G GT     S +   +AV +AIE GYR ID AAVY +E  VG+GI E +    + RE+++
Sbjct: 43  GFGTWNLKVSPENTTEAVAYAIEIGYRQIDCAAVYGNEVAVGRGIEEGLKRAGLKREDIW 102

Query: 305 VTTKLWNDKH-ARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQG 481
           VT+KLWND H + + V   L ++L+ LGL+Y+DLYLIH+PI     +   N+D+++T++ 
Sbjct: 103 VTSKLWNDHHGSYENVEKGLNQTLQDLGLEYLDLYLIHWPIGFS-SNGAKNLDHVQTYKS 161

Query: 482 MQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
           M    +     +IGVSNF+  Q+  +VS   I P  +Q+E
Sbjct: 162 MISLPK-SRVLNIGVSNFSPLQLKNVVSTGTI-PYMHQME 199


>UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto
           reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to aldo-keto reductase - Nasonia vitripennis
          Length = 310

 Score =  117 bits (282), Expect = 2e-25
 Identities = 66/190 (34%), Positives = 115/190 (60%), Gaps = 4/190 (2%)
 Frame = +2

Query: 44  LNAAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAA 223
           L AA+      ++LN+G  +P+V +GT +   +E      +++ +  +   G+R IDTA 
Sbjct: 15  LEAALTPTIRDLRLNNGYDMPLVGIGTYKVRGREV-----IKRVIDESFAVGFRSIDTAV 69

Query: 224 VYQDEEQVGQGIAEAIANGLVTREELFVTTKLW-NDKHARDQVVPALQESLKKLGLDYID 400
           VY++EE +G  + E +    + RE++F+T+KL  +D    D++  ++++SLK L   Y+D
Sbjct: 70  VYRNEEDIGLALKELLPKYNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALDTSYLD 129

Query: 401 LYLIHFPIATK-PDDSPDNIDY-LETWQGMQDARQLGLARSIGVSNFNATQITRLVSN-S 571
           LYLIH+P A++  ++SPDN    + TW  + + +Q GL RSIGVSN+    +  L+ + S
Sbjct: 130 LYLIHWPGASRILENSPDNPKLRVTTWATLVELQQKGLLRSIGVSNYTVGHLEHLLEHCS 189

Query: 572 YIRPGXNQIE 601
            ++P  NQ+E
Sbjct: 190 GVKPDVNQVE 199


>UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain
           CLIB122 of Yarrowia lipolytica; n=3; Yarrowia
           lipolytica|Rep: Yarrowia lipolytica chromosome F of
           strain CLIB122 of Yarrowia lipolytica - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 324

 Score =  117 bits (282), Expect = 2e-25
 Identities = 77/191 (40%), Positives = 105/191 (54%), Gaps = 17/191 (8%)
 Frame = +2

Query: 80  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259
           +LNDG++IP + LGT       SD    V + VY AI+ GYRHIDTA +Y  E  VG+GI
Sbjct: 8   KLNDGHSIPALGLGTA------SDG--NVEEVVYAAIKNGYRHIDTAFIYGSEVDVGKGI 59

Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 439
             AI   LV RE LFVTTK+W   + R  V  +L  SLK L LDY+DL L+H+P++   D
Sbjct: 60  KRAIDEELVKRENLFVTTKVWPTFYNR--VSESLDISLKDLSLDYVDLLLVHWPVSLLAD 117

Query: 440 -DSPDNI----------------DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSN 568
            D P  I                D++ T++ +++ +  G  +SIGVSN +   + RL+  
Sbjct: 118 SDDPRAIYLVNTDGSVRYSDSLDDWITTYKQIEEEKLSGRTKSIGVSNVSEVYLKRLLDQ 177

Query: 569 SYIRPGXNQIE 601
               P  NQ E
Sbjct: 178 VKTVPAVNQFE 188


>UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2;
           Ascomycota|Rep: Aldo/keto reductase family proteins -
           Aspergillus oryzae
          Length = 323

 Score =  117 bits (282), Expect = 2e-25
 Identities = 73/187 (39%), Positives = 102/187 (54%), Gaps = 13/187 (6%)
 Frame = +2

Query: 80  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259
           +LN G  IP + LGT      E      V  AV  A+ AGYRHID AA YQ+E +VG G 
Sbjct: 8   KLNSGYNIPAIGLGTWLSKPHE------VENAVEAALRAGYRHIDAAACYQNENEVGNGW 61

Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA---T 430
            ++   G V R+++F+T+KLWN  H  + V  A+ ++LK L  DY+DLYLIH+P+A   T
Sbjct: 62  KKS---G-VPRDQIFITSKLWNTHHHPEHVEEAVNKTLKDLQTDYLDLYLIHWPVAFEHT 117

Query: 431 KPDDSP----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 580
               +P           N+   +TW  ++   +    RSIG+SNF   +I  L+  + I 
Sbjct: 118 NETLTPIDPVTKRFRLANVPIADTWAALEKLVEAKKIRSIGISNFTQDKIDDLLKTAKIP 177

Query: 581 PGXNQIE 601
           P  NQIE
Sbjct: 178 PAVNQIE 184


>UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3;
           n=39; cellular organisms|Rep: NADPH-dependent aldose
           reductase GRE3 - Saccharomyces cerevisiae (Baker's
           yeast)
          Length = 327

 Score =  117 bits (282), Expect = 2e-25
 Identities = 73/196 (37%), Positives = 112/196 (57%), Gaps = 21/196 (10%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           + LN+G  +P+V LG  +   K   +       +Y AI+ GYR  D A  Y +E++VG+G
Sbjct: 5   VTLNNGLKMPLVGLGCWKIDKKVCAN------QIYEAIKLGYRLFDGACDYGNEKEVGEG 58

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA--- 427
           I +AI+ GLV+R+++FV +KLWN+ H  D V  AL+++L  +GLDY+DLY IHFPIA   
Sbjct: 59  IRKAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKY 118

Query: 428 ------------TKPDD------SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQIT 553
                       T  DD      +  ++  ++T++ +++    GL +SIGVSNF  + I 
Sbjct: 119 VPFEEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLIQ 178

Query: 554 RLVSNSYIRPGXNQIE 601
            L+    I+P   QIE
Sbjct: 179 DLLRGCRIKPVALQIE 194


>UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;
           n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
           reductase B - Corynebacterium sp. (strain SHS752001)
          Length = 277

 Score =  117 bits (282), Expect = 2e-25
 Identities = 71/177 (40%), Positives = 100/177 (56%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P I LNDG       LGT           DE   A+  AI++GYR +DTA  Y++E +VG
Sbjct: 5   PTISLNDGRPFAEPGLGTYNLRG------DEGVAAMVAAIDSGYRLLDTAVNYENESEVG 58

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430
           +    A+    V R+EL V +K+   +H R + V +++ SL +LGLD IDL LIH+P   
Sbjct: 59  R----AVRASSVDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHWP--- 111

Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
               +P    +L+TW+GM DAR+ GL RSIGVSNF    +  L+  + + P  NQ+E
Sbjct: 112 ----NPSVGRWLDTWRGMIDAREAGLVRSIGVSNFTEPMLKTLIDETGVTPAVNQVE 164


>UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy
           chain; n=3; Saccharomycetaceae|Rep: D-arabinose
           dehydrogenase [NAD(P)+] heavy chain - Saccharomyces
           cerevisiae (Baker's yeast)
          Length = 344

 Score =  117 bits (281), Expect = 2e-25
 Identities = 77/196 (39%), Positives = 109/196 (55%), Gaps = 23/196 (11%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
           LN+G  IP + LGT    A   + + E +QAV  AI+AGYRHIDTA  Y+ E  VG+ I 
Sbjct: 27  LNNGVRIPALGLGT----ANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIK 82

Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP------- 421
           E + +G + RE+LF+TTK+W      D+V  +L ESLK LGL+Y+DL L H+P       
Sbjct: 83  ELLEDGSIKREDLFITTKVW--PVLWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIK 140

Query: 422 --------IATKPDDSPDNI-----DYLETWQGMQDA---RQLGLARSIGVSNFNATQIT 553
                   + T  DDS   +     DYLET++ ++           R+IGVSNF+   + 
Sbjct: 141 DPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLE 200

Query: 554 RLVSNSYIRPGXNQIE 601
           RL+    ++P  NQ+E
Sbjct: 201 RLIKECRVKPTVNQVE 216


>UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus obeum ATCC 29174|Rep: Putative
           uncharacterized protein - Ruminococcus obeum ATCC 29174
          Length = 263

 Score =  116 bits (280), Expect = 3e-25
 Identities = 70/159 (44%), Positives = 94/159 (59%)
 Frame = +2

Query: 125 GRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 304
           G G  K +D++ E   A+  A++ GYR +DTA+ Y++EE VG GIA+    G V R++LF
Sbjct: 5   GLGLYKTTDAV-EAEDAIAAAVQNGYRLLDTASAYKNEEFVGCGIAKC---G-VPRKDLF 59

Query: 305 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 484
           +TTK+WN+      V  A Q SL +LGLDYIDLYLIH+P+            +L TW+ M
Sbjct: 60  ITTKIWNNAQRLGDVEGAFQRSLDRLGLDYIDLYLIHWPVPG---------CFLNTWKDM 110

Query: 485 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
           +   + G A SIGVSNF    +  L   S I P  NQIE
Sbjct: 111 EKILESGRALSIGVSNFEIRHLEELRRVSGIVPAVNQIE 149


>UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1;
           Propionibacterium freudenreichii subsp. shermanii|Rep:
           Putative aldo-keto reductase - Propionibacterium
           freudenreichii subsp. shermanii
          Length = 280

 Score =  116 bits (279), Expect = 4e-25
 Identities = 68/177 (38%), Positives = 105/177 (59%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P ++L+ G  +P++ +GT           +E R AV  AIE GYR +DTA  Y +EE VG
Sbjct: 9   PTVELSGGTRMPMLGMGTWPLKG------EECRAAVASAIEQGYRLVDTAEAYGNEEAVG 62

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430
           + + EA  +    R E+FVTTK     H+R  V  AL+ SL++LGLDY+DL+L+H+P+  
Sbjct: 63  KAVREAGPD----RAEIFVTTKFSKQWHSRKGVHEALEHSLERLGLDYVDLFLMHWPM-- 116

Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                P    Y++ ++GM + ++ GLA++IGVSNF    +  L++   + P  NQI+
Sbjct: 117 -----PGEGSYVDAYRGMVELKEQGLAKAIGVSNFKVHHLDDLITEG-MTPEVNQIQ 167


>UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;
           n=1; Rhodobacterales bacterium HTCC2150|Rep:
           2,5-diketo-D-gluconic acid reductase A - Rhodobacterales
           bacterium HTCC2150
          Length = 334

 Score =  116 bits (279), Expect = 4e-25
 Identities = 74/189 (39%), Positives = 98/189 (51%), Gaps = 7/189 (3%)
 Frame = +2

Query: 56  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235
           M   A    LN   TIP V  GT         S D+ +  +  AI+AGYRHIDTA+ YQ+
Sbjct: 33  MTNTATTFTLNTTTTIPAVGFGT------YLISNDDAKSTISAAIQAGYRHIDTASGYQN 86

Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHA-------RDQVVPALQESLKKLGLDY 394
           E+ VG GI   + +  +TR++LFVT KLW    A       + Q +     SL +LGLDY
Sbjct: 87  EKTVGAGIKAGLQSAGITRKDLFVTAKLWPGNPAWGDAPKTKAQTLDECDASLARLGLDY 146

Query: 395 IDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 574
           +DLYLIH P              LE W+ + + +  G ARSIGVSNFN + +  + +   
Sbjct: 147 VDLYLIHAPYGGDM--------RLEQWRALLELQANGKARSIGVSNFNESHLNEIKAAGL 198

Query: 575 IRPGXNQIE 601
             P  NQIE
Sbjct: 199 PMPDANQIE 207


>UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep:
           Oxidoreductase - Lactobacillus plantarum
          Length = 282

 Score =  116 bits (278), Expect = 6e-25
 Identities = 73/182 (40%), Positives = 98/182 (53%)
 Frame = +2

Query: 56  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235
           M V     QL +G  IP VA GT +    E+       QAV  A+ AGYRHIDTA  YQ+
Sbjct: 1   MTVLTTMYQLANGVNIPKVAFGTWQIPGGEA-----TYQAVRAALAAGYRHIDTALAYQN 55

Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415
           E  VGQ    AI +  + RE++FVTTKL  +  +    +     SLK LGLDY+DLYL+H
Sbjct: 56  EASVGQ----AIRDSGIPREQIFVTTKLPAETKSYQGALNDFDRSLKNLGLDYVDLYLVH 111

Query: 416 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQ 595
            P          +   L+ WQ M+   Q G A++IGVSNF    +  +++ + I P  NQ
Sbjct: 112 APWPWGQVGRVYDEANLDVWQAMEAIYQSGRAKAIGVSNFAVRDLKNILNQATIPPMVNQ 171

Query: 596 IE 601
           I+
Sbjct: 172 IQ 173


>UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase
           family protein; n=1; Tetrahymena thermophila SB210|Rep:
           oxidoreductase, aldo/keto reductase family protein -
           Tetrahymena thermophila SB210
          Length = 295

 Score =  115 bits (277), Expect = 8e-25
 Identities = 63/175 (36%), Positives = 103/175 (58%), Gaps = 1/175 (0%)
 Frame = +2

Query: 80  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259
           +L +G+ +P+  LGT +  +KE     E+   +  A++ GYRHIDTA +Y++E+Q+G  +
Sbjct: 9   ELCNGSKLPVFGLGTYKVVSKE-----EMVTFLRTALDLGYRHIDTAIMYENEKQIGDAL 63

Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 439
            E    G   RE+LF+ TKL+++K+ +  V   +++SL+ L  +YIDLYL+H+  +   D
Sbjct: 64  QEIYKEGKYKREDLFLVTKLFSNKNTK--VEDQVRQSLQNLQTNYIDLYLLHYASSPPTD 121

Query: 440 D-SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                +    + W   ++  Q GL R+IG+SNFN   +  L S   I+P  NQIE
Sbjct: 122 QFELTHKPVFQVWAEFEELVQKGLIRNIGISNFNVQMLLDLYSYCKIKPVVNQIE 176


>UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like
           protein 1; n=14; Eutheria|Rep: Aldo-keto reductase
           family 1 member C-like protein 1 - Homo sapiens (Human)
          Length = 302

 Score =  115 bits (277), Expect = 8e-25
 Identities = 58/123 (47%), Positives = 80/123 (65%)
 Frame = +2

Query: 65  QAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 244
           Q+  ++LNDG  +P++  GT    A +     +  +A   AI+ G+RHID+A +YQ+EE+
Sbjct: 7   QSHSVRLNDGPFMPVLGFGT---YAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEE 63

Query: 245 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424
           VGQ I E IA+G V REE+F T KLW      + V PAL+ SLKKLG DY+DL++IH P 
Sbjct: 64  VGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPF 123

Query: 425 ATK 433
           A K
Sbjct: 124 AMK 126


>UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:
           Aldo/keto reductase - Kineococcus radiotolerans SRS30216
          Length = 343

 Score =  115 bits (276), Expect = 1e-24
 Identities = 70/189 (37%), Positives = 104/189 (55%), Gaps = 12/189 (6%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P  +L  G T+P + +GT  G+ + S +  EV  AV  A+ AGYR +D AAVY +E QVG
Sbjct: 14  PRRELRGGATVPAIGIGTF-GSDRYSPA--EVAAAVAGAVAAGYRLVDCAAVYGNEAQVG 70

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI-- 424
           + +A A+A G V R+ELFV +K+WND HA    V ++  SL+ L LD++D   +H+P   
Sbjct: 71  EALAGAVAGG-VDRDELFVVSKVWNDAHAPADAVASVHRSLRDLRLDHLDAVFVHWPFPN 129

Query: 425 ---------ATKPDDSP-DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 574
                    A  P   P D+  YL  W  ++     GL R +G SN    ++  L+ ++ 
Sbjct: 130 HHPPMADTDARDPRARPYDHDAYLALWGALEGLVDSGLVRHLGTSNTTVAKLDLLLRDAR 189

Query: 575 IRPGXNQIE 601
           I P  N++E
Sbjct: 190 IPPALNEME 198


>UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon
           cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon
           cuniculi
          Length = 301

 Score =  115 bits (276), Expect = 1e-24
 Identities = 68/185 (36%), Positives = 103/185 (55%), Gaps = 11/185 (5%)
 Frame = +2

Query: 80  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259
           +LN+G  IP V LGT      E +++ E   A+  A+  GYRHIDTA +Y +E+ +G  +
Sbjct: 7   KLNNGKEIPTVGLGTW---GMEDEAVLE--GAIRNALSLGYRHIDTAFIYGNEKMIGNIL 61

Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA--TK 433
            +    G+V R++LF+T+KLWN  H   +    L+ SL  L +DY+DLYLIH+P+     
Sbjct: 62  KKLFDEGVVQRKDLFITSKLWNTFHGCPE--DGLRRSLNDLQMDYVDLYLIHWPVTFDPA 119

Query: 434 PDDSPDN---------IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPG 586
           PD + ++          D +  W+ M+    LGLA+SIG+SNF      +++    I P 
Sbjct: 120 PDGTVESCGKKYNVGKFDAVGVWKKMEALVDLGLAKSIGISNFGKANTEKILGTCRICPA 179

Query: 587 XNQIE 601
             QIE
Sbjct: 180 AIQIE 184


>UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase;
           n=2; Parasitella parasitica|Rep:
           4-dihydromethyltrisporate dehydrogenase - Parasitella
           parasitica
          Length = 321

 Score =  115 bits (276), Expect = 1e-24
 Identities = 69/164 (42%), Positives = 89/164 (54%), Gaps = 17/164 (10%)
 Frame = +2

Query: 161 EVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR 340
           +    +Y AI+ GYR  D A  Y +E +VG+GI +AI  GLV REELF+ TKLWN  H++
Sbjct: 29  DAENTIYQAIKIGYRLFDGACDYGNEVEVGRGINKAIKEGLVKREELFIVTKLWNTFHSK 88

Query: 341 DQVVPALQESLKKLGLDYIDLYLIHFPIATK---------PDDSPDNIDYL--------E 469
             V  A    LK  GL+Y DLYLIHFPI  +         P+    + D L        E
Sbjct: 89  QHVRTAFDRQLKDWGLEYFDLYLIHFPIPLQYVDPAVSYPPEWYVPHADKLNFERSPIHE 148

Query: 470 TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
            W  M+   Q  L R+IGV+NFN   I  L+S + I+P   QIE
Sbjct: 149 CWAEMEKLVQAKLTRNIGVANFNCQAILDLLSYAKIKPAVLQIE 192


>UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase
           family; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
           oxidoreductase, aldo/keto reductase family - Entamoeba
           histolytica HM-1:IMSS
          Length = 307

 Score =  114 bits (275), Expect = 1e-24
 Identities = 74/181 (40%), Positives = 105/181 (58%), Gaps = 8/181 (4%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ-GI 259
           LN+G  +P + LGT            EV +AV  A+E GYR ID A  Y++E+++G+ GI
Sbjct: 8   LNNGKFMPAIGLGTWLAAP------GEVGKAVTLALENGYRLIDCARFYKNEKEIGEMGI 61

Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 439
              + N    REELFVT+KLW D+  R  +  +  ES++ L   Y+DLYLIH+PIA K D
Sbjct: 62  EPFLKNH--PREELFVTSKLWMDQVTR--IRESCLESIQDLKCKYLDLYLIHWPIALKVD 117

Query: 440 DS----PDN---IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598
            S    P++   +D  E WQ M+     GL +SIG+SNF   QI +++    I+P  NQ+
Sbjct: 118 ASNPPKPEDFLDMDITEIWQEMERLVDEGLVKSIGLSNFTIPQIEKIMKMCRIKPVINQV 177

Query: 599 E 601
           E
Sbjct: 178 E 178


>UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase
           family protein; n=3; Tetrahymena thermophila SB210|Rep:
           oxidoreductase, aldo/keto reductase family protein -
           Tetrahymena thermophila SB210
          Length = 299

 Score =  114 bits (274), Expect = 2e-24
 Identities = 63/177 (35%), Positives = 99/177 (55%), Gaps = 2/177 (1%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           I L++G  +P   LG+ R       S++EV   +  A++ GYRHIDTA +Y++E+ +G  
Sbjct: 10  ITLSNGQKMPAFGLGSSR-----VQSVEEVTNLIRKALDVGYRHIDTAQMYENEQFIGAA 64

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
           +      G   RE++F+ TK  + K      +  ++E L+KL +DY+DL LIH P+A   
Sbjct: 65  LKTIFGEGKYKREDIFLVTKQASIKGV--SCLEIMKEQLQKLQVDYVDLLLIHVPLAAPS 122

Query: 437 DDSP--DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
           DD    ++    + W   ++   LGLA+ +GVSNFN   I  L++   I+P  NQIE
Sbjct: 123 DDYQQWNHKPVHQIWAEFEEIHSLGLAKGLGVSNFNCQMIIDLLAYCKIKPLVNQIE 179


>UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;
           Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
           Oceanobacillus iheyensis
          Length = 280

 Score =  114 bits (274), Expect = 2e-24
 Identities = 75/182 (41%), Positives = 99/182 (54%)
 Frame = +2

Query: 56  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235
           M  Q P + L+DG TIP V  GT R     +D +    QA+  AI+ GYR IDTA  Y++
Sbjct: 1   MVNQIPNVTLHDGLTIPKVGFGTYR--LNGNDGV----QAINNAIDHGYRLIDTAYNYEN 54

Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415
           E  VG    EA+      RE+L +T+KL    H  D+ V  +QESL +  LDY DLYLIH
Sbjct: 55  EGTVG----EAVRRSSTPREQLLITSKLPGRYHHYDKAVTTIQESLYRANLDYYDLYLIH 110

Query: 416 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQ 595
           +P       +P    Y+E WQ + +A++ G  RSIGV NF    + RL   +   P  NQ
Sbjct: 111 WP-------NPIQDIYVEAWQALIEAKRRGYIRSIGVCNFLPEHLERLKQETGELPTINQ 163

Query: 596 IE 601
           IE
Sbjct: 164 IE 165


>UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=2; Lactobacillus|Rep: Aldo/keto
           reductase of diketogulonate reductase family -
           Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
          Length = 273

 Score =  114 bits (274), Expect = 2e-24
 Identities = 70/175 (40%), Positives = 101/175 (57%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           + LN+   IPI   GT         S D+ +QAV  A E GYR IDTA  YQ+E+QVG+ 
Sbjct: 4   LTLNNDVKIPIFGFGT------YEISPDQTKQAVLSAFEEGYRLIDTAQYYQNEQQVGEA 57

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
           +    A+GL  R+E+F+TTK   D +   ++   L ESL+++GLDY DL LIH+P+    
Sbjct: 58  VK---ASGL-NRDEVFITTKTMTDGYEDTKI--GLDESLRRIGLDYFDLVLIHWPMGHD- 110

Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                    ++TW  ++ A + G  R+IG+SNFN+ Q   L+  S +RP  +QIE
Sbjct: 111 ---------IDTWHALEAAYKAGKTRAIGISNFNSRQTLDLIHQSSVRPMVDQIE 156


>UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr1 scaffold_5, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 247

 Score =  114 bits (274), Expect = 2e-24
 Identities = 67/179 (37%), Positives = 102/179 (56%), Gaps = 10/179 (5%)
 Frame = +2

Query: 92  GNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI 271
           G  IP+V + T       S+++ +   ++  AIE GYRH D  A Y  E+ +G+ I +A+
Sbjct: 13  GKAIPLVGMVTTVYPFAPSETMID---SILTAIELGYRHFDCVAAYLSEKPLGEAIKKAV 69

Query: 272 ANGLV-TREELFVTTKLWNDKHARDQVVPALQESLK---------KLGLDYIDLYLIHFP 421
             GL+ +R+ELF+T+KLW      D+V+PALQ +LK          L LDY+DLYLIH+ 
Sbjct: 70  KLGLIKSRDELFITSKLWCSDAHHDRVLPALQNTLKISSILSFSKNLQLDYLDLYLIHWS 129

Query: 422 IATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598
               P      ID    W+ M+D ++L L ++IGVSNF+  ++  L+  + I P  NQ+
Sbjct: 130 DGHLP------IDLGSVWKAMEDFQKLSLTKAIGVSNFSCNKLEELLQTASILPAVNQV 182


>UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family
           protein; n=4; Oligohymenophorea|Rep: Oxidoreductase,
           aldo/keto reductase family protein - Tetrahymena
           thermophila SB210
          Length = 297

 Score =  114 bits (274), Expect = 2e-24
 Identities = 64/182 (35%), Positives = 105/182 (57%), Gaps = 2/182 (1%)
 Frame = +2

Query: 62  VQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEE 241
           V+ P +   +G +IP +  GT     +++D I  V +A    ++ GY HIDTA+VY++E+
Sbjct: 11  VKVPILNFREGGSIPQIGYGTYE--LRQNDCIIGVTEA----LKIGYTHIDTASVYRNEQ 64

Query: 242 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 421
            + + I    A G + RE+LF+T+K+   +   +Q   A+Q+ L +L + Y+D  LIH+P
Sbjct: 65  DIAKVIHNP-AYG-IKREDLFITSKISPGEQGYEQAKKAVQDMLTRLNIKYLDCVLIHWP 122

Query: 422 IATK-PDDSPDNIDY-LETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQ 595
             +K P + P N    LETW+ + + R+ G+ + IGVSNFN   +  L+  S  +P  NQ
Sbjct: 123 GVSKLPPNDPKNAQIRLETWKALIELRKAGVIKHIGVSNFNINHLQHLIEKSEFKPEMNQ 182

Query: 596 IE 601
            E
Sbjct: 183 FE 184


>UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase
           family protein; n=1; Tetrahymena thermophila SB210|Rep:
           oxidoreductase, aldo/keto reductase family protein -
           Tetrahymena thermophila SB210
          Length = 323

 Score =  113 bits (272), Expect = 3e-24
 Identities = 64/180 (35%), Positives = 104/180 (57%), Gaps = 5/180 (2%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           +QLN+G  +P++ LGT         +++E+   +  A++ GYR+ DTA  Y++E ++GQ 
Sbjct: 15  VQLNNGYKMPLLGLGTQPYDIVTRVTVEEMTTLLSNALDFGYRNFDTAKQYRNEVEIGQA 74

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF---PIA 427
                  G   RE++F+TTKL+  K    ++   +Q SL +L   YIDLYLI +   P+ 
Sbjct: 75  FQNIFQQGKYKREDVFITTKLFPFK-IEKKIKEVVQNSLDQLQTSYIDLYLIQWSFTPVL 133

Query: 428 TKPDDS--PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
           T  D S   ++    E W+ +++  +LG+ RSIGV+NFN   +  L+S + I+P  NQIE
Sbjct: 134 TNFDGSVAVNHRPIHEVWRELEECVELGMIRSIGVANFNCQMVLDLLSYAKIKPVVNQIE 193


>UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:
           Oxidoreductase - Lactobacillus plantarum
          Length = 288

 Score =  113 bits (271), Expect = 4e-24
 Identities = 72/179 (40%), Positives = 94/179 (52%)
 Frame = +2

Query: 65  QAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 244
           + P I LNDG  IP +    G GT +  D      QAV  A+  GYRHIDTA  Y +E++
Sbjct: 3   KTPTITLNDGRAIPAI----GFGTFQIPDD-GSTYQAVKEALVIGYRHIDTAVAYFNEDE 57

Query: 245 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424
           VGQ    AI +  + R++++VT+KLW   +  D    A+  SL KL LDYIDLYLIH P 
Sbjct: 58  VGQ----AIKDSGIPRDQIWVTSKLWLQDYGFDAASRAIDRSLTKLRLDYIDLYLIHQPY 113

Query: 425 ATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
              P            WQ M+ A++ G  +SIGVSN   T   + V      P  NQ+E
Sbjct: 114 GDVPG----------AWQAMEAAQKAGKLKSIGVSNMTPTLWQKFVPQFETIPAVNQVE 162


>UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid
           reductase; n=1; Gluconobacter oxydans|Rep: Putative
           2,5-diketo-D-gluconic acid reductase - Gluconobacter
           oxydans (Gluconobacter suboxydans)
          Length = 279

 Score =  113 bits (271), Expect = 4e-24
 Identities = 63/175 (36%), Positives = 99/175 (56%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           I  +DG+T+P + LG            DE  + V  A++ GYR +DTA +Y++EE VG+G
Sbjct: 14  ISFHDGHTMPQIGLGVWETPP------DETAEVVKEAVKLGYRSVDTARLYKNEEGVGKG 67

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
           + +          E+F+TTKLWND+   D  + A +ES + L    +DLYLIH+P+    
Sbjct: 68  LED--------HPEIFLTTKLWNDEQGYDSTLRAYEESARLLRRPVLDLYLIHWPM---- 115

Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
              P    Y+ETW+ + + ++ G  +SIGVSNF +  + R++  + + P  NQIE
Sbjct: 116 ---PAQGQYVETWKALVELKKSGRVKSIGVSNFESEHLERIMDATGVVPVVNQIE 167


>UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales
           bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
           bacterium HTCC2654
          Length = 278

 Score =  113 bits (271), Expect = 4e-24
 Identities = 74/178 (41%), Positives = 103/178 (57%)
 Frame = +2

Query: 68  APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247
           AP + L +G  +P + LGT   T       DE  +AV  AIE GYR IDTA  Y++E  V
Sbjct: 7   APTVTLANGVEMPQLGLGTWPMTD------DEAAKAVATAIETGYRLIDTAENYKNETGV 60

Query: 248 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427
           GQGI +A   G V R+E+F+TTK+    H+ D    A + SL++LGLDYIDL+LIH+P  
Sbjct: 61  GQGIRDA---G-VARDEVFLTTKMNKQWHSVDGARRACEASLERLGLDYIDLFLIHWP-- 114

Query: 428 TKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                +PD   Y+E ++G+      GL R+IG SNF    +  L +  ++ P  NQI+
Sbjct: 115 -----NPDQGTYVEAFEGLTRLLDAGLVRAIGTSNFLPHHLNDLFAAGFV-PHVNQIQ 166


>UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
           Aldehyde reductase - Lactobacillus acidophilus
          Length = 278

 Score =  112 bits (270), Expect = 5e-24
 Identities = 64/175 (36%), Positives = 100/175 (57%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           + LN+G  +P +  G       + D + + +Q V   +E GYR +DTA +Y +E+ VG  
Sbjct: 5   VTLNNGIKMPRLGFGV-----YQIDDLAQAQQVVEDGLEVGYRLVDTAQIYGNEQAVG-- 57

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
             +AI +  V RE++F+T+K+W D +  D  + A  +S+KKL LDYIDLYLIH P     
Sbjct: 58  --DAIKHSNVPREDIFITSKIWVDDYGYDNTLKAFDDSMKKLQLDYIDLYLIHKPYN--- 112

Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                  DY  TW+ ++   Q G  R+IGVS+F   ++  L++ + ++P  NQIE
Sbjct: 113 -------DYYGTWRALERLYQEGRIRAIGVSSFWNERLADLITFNDVKPAVNQIE 160


>UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family;
           n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto
           reductase family - Lactobacillus acidophilus
          Length = 289

 Score =  112 bits (270), Expect = 5e-24
 Identities = 70/177 (39%), Positives = 96/177 (54%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P I+LNDGN IP +  G       +  + DE  +AV  AI  GYR IDTA  Y ++  VG
Sbjct: 5   PKIKLNDGNEIPQLGFGVF-----QISNHDEAVKAVESAISNGYRLIDTAEAYNNQTAVG 59

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430
               EAI N  V R+++F+TTKLW      ++   A+ E LK+LG DYID+ L+H     
Sbjct: 60  ----EAIKNSDVNRDDIFLTTKLWVSNFTYEKASKAIDEDLKELGTDYIDMMLLHQAYG- 114

Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                    D    W+ ++DA++ G  +SIGVSNF   Q+  L   S ++P  NQIE
Sbjct: 115 ---------DVAGAWRALEDAQKAGKTKSIGVSNFWPDQLMNLQLMSNVKPVVNQIE 162


>UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=1; Lactobacillus brevis ATCC
           367|Rep: Aldo/keto reductase of diketogulonate reductase
           family - Lactobacillus brevis (strain ATCC 367 / JCM
           1170)
          Length = 268

 Score =  112 bits (270), Expect = 5e-24
 Identities = 66/174 (37%), Positives = 103/174 (59%)
 Frame = +2

Query: 80  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259
           QL++G TIP++  GT    +K+      V  A+  A++AGYRH+D A +Y +E  VG+ I
Sbjct: 5   QLSNGVTIPMLGFGTYLIDSKD------VPAAIKTALDAGYRHLDCAHIYGNEPAVGEAI 58

Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 439
               A+G + R +LF+T+K+WN     D+ + A  ++L  L LDY+DLYLIH+P     D
Sbjct: 59  K---ASG-IDRSDLFITSKVWNADQGYDKTLAAFDQTLSDLQLDYLDLYLIHWP---NED 111

Query: 440 DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
           D    +D   TW+ ++   Q    R+IGVSNF+  Q+ ++   + ++P  NQIE
Sbjct: 112 DFELTLD---TWRVLETLYQQKKVRAIGVSNFSEDQLKQVFEMATVKPMINQIE 162


>UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep:
           AkrI - Butyrivibrio fibrisolvens
          Length = 172

 Score =  112 bits (270), Expect = 5e-24
 Identities = 57/153 (37%), Positives = 94/153 (61%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           I+LN+G  IP+     G GT K  D  +E   +V  A++ GYRHIDTAA Y++E+ V   
Sbjct: 8   IKLNNGTAIPMF----GYGTYKIKDQ-NEAYNSVRLALKNGYRHIDTAAFYENEKFVANA 62

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
           I + +      RE++FVT+K W  +   D+ + A ++++ ++ +DY+DLYL+H+P +   
Sbjct: 63  IKDFMEESQTKREDIFVTSKAWKTELGYDKTLAAFEKTMNEMQMDYLDLYLVHWPASYAF 122

Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNF 535
           DD  +N +  +TW+ M +  + G  ++IGVSNF
Sbjct: 123 DDDWENTN-RQTWKAMTEIYKSGRVKAIGVSNF 154


>UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=1; Leuconostoc mesenteroides subsp.
           mesenteroides ATCC 8293|Rep: Aldo/keto reductase of
           diketogulonate reductase family - Leuconostoc
           mesenteroides subsp. mesenteroides (strain ATCC 8293
           /NCDO 523)
          Length = 288

 Score =  112 bits (269), Expect = 7e-24
 Identities = 65/160 (40%), Positives = 92/160 (57%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
           LN+G  +P +  G  +  A+E+      +QAV  AI AGYR IDTA VY +E + GQG+ 
Sbjct: 6   LNNGAQMPQLGFGVFQIPAEET------KQAVVDAINAGYRSIDTARVYGNEAETGQGVN 59

Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 442
           EAIAN +V REELF+TTKLW  + + +    A+ +SLKKLG DY DL L+H P       
Sbjct: 60  EAIANAVVAREELFLTTKLWLSEFSYEAAKGAIDDSLKKLGTDYADLILLHQPYG----- 114

Query: 443 SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 562
                D    ++ + +A+  G  +SIG+SNF   +    +
Sbjct: 115 -----DVYGAYKALAEAQADGKVKSIGISNFYPAKFVEFI 149


>UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family
           protein; n=9; Trichomonas vaginalis G3|Rep:
           Oxidoreductase, aldo/keto reductase family protein -
           Trichomonas vaginalis G3
          Length = 308

 Score =  112 bits (269), Expect = 7e-24
 Identities = 68/185 (36%), Positives = 100/185 (54%), Gaps = 16/185 (8%)
 Frame = +2

Query: 95  NTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIA 274
           N IP + LGT +    E    D V    Y   EAGY HID A  Y++E+ VGQ + +   
Sbjct: 2   NRIPTIGLGTWKSPRSE----DLVNAITYAIKEAGYVHIDCALCYENEDIVGQALQQCWD 57

Query: 275 NGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA--------- 427
           +G + RE +++T+KLWN  H  + V  A +++LK L LDY+DLYL+H+P A         
Sbjct: 58  SG-IKRENIWITSKLWNTHHRLEIVEEACRKTLKDLRLDYLDLYLMHYPFAFQNTGIGGS 116

Query: 428 TKPDDS------PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRL-VSNSYIRPG 586
             P D        D +  ++TW+ M+   + GL + IGVSN+   Q+ RL  S++   P 
Sbjct: 117 LNPLDEKGNTIFDDGVSLIDTWKAMEKLVEKGLVKRIGVSNWTINQLERLKYSDAKTTPY 176

Query: 587 XNQIE 601
            NQ+E
Sbjct: 177 TNQVE 181


>UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep:
           Lin2349 protein - Listeria innocua
          Length = 294

 Score =  111 bits (267), Expect = 1e-23
 Identities = 69/171 (40%), Positives = 99/171 (57%), Gaps = 1/171 (0%)
 Frame = +2

Query: 92  GN-TIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEA 268
           GN TIP + LG  + T +E      +  AV  AIE GYR  DTAAVY +E  VGQ    A
Sbjct: 13  GNETIPYIGLGVFQVTEQEF-----IAGAVEKAIEVGYRLFDTAAVYNNEAIVGQ----A 63

Query: 269 IANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSP 448
           I +  V REELF+++K+WN     D+ + A + +L+ L LDY+DLYLIH+P+A K     
Sbjct: 64  ILDSAVPREELFISSKVWNGDLGYDETLFAFERTLRNLKLDYLDLYLIHWPVAGK----- 118

Query: 449 DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
               Y ++W+ M+      L +SIGV+NF    ++ L+  +  +P  NQ+E
Sbjct: 119 ----YRDSWRAMERLHDEKLIKSIGVANFKQHHLSDLLVAANEKPVLNQVE 165


>UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4;
           Bifidobacterium|Rep: Dehydrogenase or reductase protein
           - Bifidobacterium longum
          Length = 289

 Score =  111 bits (267), Expect = 1e-23
 Identities = 69/177 (38%), Positives = 98/177 (55%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P I L DG++IP V LG  R    + + +  V ++   A+EAGYRHID AA Y +E  VG
Sbjct: 12  PDIALKDGHSIPQVGLGVLR---IDDEGVVPVVES---ALEAGYRHIDGAAGYNNEAGVG 65

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430
           + +A +  N    RE L+VTTKL + +   D  + A   SLK L LDY+D+Y+IH+P   
Sbjct: 66  RALAASGYNKGAKRETLWVTTKLRDSQQGYDSALKAFDNSLKLLQLDYVDMYMIHWP--- 122

Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
               +P +    +TW+     R  G+AR++GV NF    + RL   +   P  NQIE
Sbjct: 123 ----TPFDWRSTDTWKAFVKLRDEGMARTLGVCNFMPADLKRLHEETGAWPAVNQIE 175


>UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2;
           Lactobacillus reuteri|Rep: 2,5-didehydrogluconate
           reductase - Lactobacillus reuteri F275
          Length = 300

 Score =  111 bits (267), Expect = 1e-23
 Identities = 68/178 (38%), Positives = 104/178 (58%), Gaps = 1/178 (0%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P I+LN+G+ IP + LG  +       S+ E +Q V  AI   Y  IDTA  Y +E  VG
Sbjct: 11  PKIKLNNGHLIPQLGLGVWKA------SLAETQQMVKEAIMNDYVLIDTAKQYGNEAAVG 64

Query: 251 QGIAEAIANGLVTREELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427
           QGI +        R+ +F+TTK++N D+   D++  A+ E LKKL  +Y+DL L+H+P+ 
Sbjct: 65  QGIQDGFKATGRKRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLLLHWPVN 124

Query: 428 TKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
            K         Y E+W+ ++D  + G A++IGV NFN  ++T L+ ++ I+P  NQIE
Sbjct: 125 DK---------YNESWRALEDIYKDGQAKAIGVCNFNVERMTDLLDHAKIKPAINQIE 173


>UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium
           discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
           discoideum AX4
          Length = 305

 Score =  111 bits (267), Expect = 1e-23
 Identities = 69/185 (37%), Positives = 106/185 (57%), Gaps = 10/185 (5%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           I LN+ N  PI     G GT K    ++++   +   +E GYR IDTA++Y +EE++G+ 
Sbjct: 15  IILNELNLNPIKMPMLGIGTFK----LNDIENIIKVGLENGYRRIDTASMYNNEERIGKV 70

Query: 257 IAEAIA--NGL----VTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 418
           + E +   +GL    + RE+LF+T+K    +   +  + A + SLKKL LDY+D YLIH+
Sbjct: 71  LNEMVTKNDGLDGKKIKREDLFITSKCSFMEQGYENALKAFESSLKKLQLDYLDCYLIHW 130

Query: 419 PIATKPD--DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVS--NSYIRPG 586
           P     D  DS ++I   +TW+ ++   Q    RSIGVSN+    +T L+S  N  I+P 
Sbjct: 131 PGVKGLDGSDSGNSIQRAQTWRALEKLYQDKKVRSIGVSNYTINHLTELLSSPNLQIKPA 190

Query: 587 XNQIE 601
            NQ+E
Sbjct: 191 INQVE 195


>UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=10;
           Pezizomycotina|Rep: Related to aldo-keto reductase YPR1
           - Neurospora crassa
          Length = 322

 Score =  111 bits (267), Expect = 1e-23
 Identities = 69/184 (37%), Positives = 99/184 (53%), Gaps = 7/184 (3%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQ----AVYWAIEAGYRHIDTAAVYQDE 238
           P ++L+DGN IP++  G G    K  DS D + +    A   A+ AGY H+D A VY +E
Sbjct: 25  PSLKLSDGNEIPMLGYGLGTANYKSGDSADTISEPIVNATLTALNAGYAHLDGAEVYGNE 84

Query: 239 EQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 418
            ++G+    AIA   + R  L++TTK      A D V  +   SL+KLGLDY+DLYL+H 
Sbjct: 85  VELGR----AIAQSKLPRSSLYITTK--TIVRAGDTVTQSFNRSLEKLGLDYVDLYLLHS 138

Query: 419 PIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV---SNSYIRPGX 589
           P   K   +P+ +     W+ M+  +  G+A+SIGVSNF  + +  L          P  
Sbjct: 139 PFFAK---NPEQLQ--AAWREMEKIKDSGMAKSIGVSNFLISHLQTLFDIPGGLQYPPVV 193

Query: 590 NQIE 601
           NQIE
Sbjct: 194 NQIE 197


>UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;
           Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
           Acinetobacter sp. (strain ADP1)
          Length = 297

 Score =  111 bits (266), Expect = 2e-23
 Identities = 68/177 (38%), Positives = 104/177 (58%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P + L+DG++IP  ALG G  T K    +D + +A    +  GYR +D+A  Y++E  VG
Sbjct: 23  PDLILHDGHSIP--ALGFGTYTLKGQQGVDTMLRA----LGHGYRMLDSAFNYENEGAVG 76

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430
             + ++   GL+ R+E+F+T+KL    HA D+ +  ++ESL ++  DY+DLYLIH+P   
Sbjct: 77  AAVRQS---GLL-RDEIFITSKLPGRHHAYDKAMETIEESLYRMQFDYLDLYLIHWP--- 129

Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
               +P    Y+E WQ + DA++ G  RSIGVSNF    I  L   + + P  NQ+E
Sbjct: 130 ----NPQQGLYIEAWQALIDAQKKGYIRSIGVSNFLPKHIETLRRETGVIPVINQVE 182


>UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus
           terreus NIH2624|Rep: Predicted protein - Aspergillus
           terreus (strain NIH 2624)
          Length = 292

 Score =  111 bits (266), Expect = 2e-23
 Identities = 69/183 (37%), Positives = 100/183 (54%), Gaps = 6/183 (3%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKE--SDSID-EVRQAVYWAIEAGYRHIDTAAVYQDEE 241
           P + L DGN +PI+  GTG    K+  +D  + E+ + +  A+E G+ HID A  Y  E 
Sbjct: 4   PALSLKDGNLVPILGFGTGTAWYKDDPNDPTNPELIEVLKAALEKGFHHIDAADSYGTER 63

Query: 242 QVGQGIAEAIANGLVTREELFVTTKL---WNDKHARDQVVPALQESLKKLGLDYIDLYLI 412
           +VG  I E+   G + RE+LF+TTK+   W D      V  AL  SL++L LDY+DLYL+
Sbjct: 64  EVGIAIRES---G-IPREQLFITTKVLEGWKD------VPGALDASLERLQLDYVDLYLL 113

Query: 413 HFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXN 592
           H P        P+  D    W+G++  +  G ARSIGVSNF    +  ++    + P  N
Sbjct: 114 HNPYVI-----PNLTDIQSAWKGLEAVKATGKARSIGVSNFQRNHLEAILETCSVVPAIN 168

Query: 593 QIE 601
           Q+E
Sbjct: 169 QLE 171


>UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde
           reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep:
           NADH/NADPH dependent indole-3-acetaldehyde reductase
           AKR3C2 - Schizosaccharomyces pombe (Fission yeast)
          Length = 284

 Score =  111 bits (266), Expect = 2e-23
 Identities = 71/172 (41%), Positives = 94/172 (54%), Gaps = 2/172 (1%)
 Frame = +2

Query: 92  GNTIPIVALGTGRGT-AKESDSIDE-VRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAE 265
           G  IP+ A G G     KE   I+  +  +V  A+ AG+ HID A VY +EE+VG  + E
Sbjct: 7   GPKIPVPAYGVGTALFKKEKGEINRTIVDSVKNALAAGFIHIDCAEVYGNEEEVGVALKE 66

Query: 266 AIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDS 445
           A     V R +LF+T+K+    H  D +  AL ESL+KLG DY+DLYL+H PI       
Sbjct: 67  AN----VPRSKLFITSKVM---HNVDNIPEALNESLRKLGTDYLDLYLLHSPIPFYEKKI 119

Query: 446 PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
           P +    E W+ M+ A   GL  S+GVSNF    +  L+  S I P  NQIE
Sbjct: 120 PIS----EGWKAMETALGTGLVHSVGVSNFRIPDLEELLKTSTITPRVNQIE 167


>UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1;
           Griffithsia japonica|Rep: Mannose 6-phosphate reductase
           - Griffithsia japonica (Red alga)
          Length = 174

 Score =  102 bits (245), Expect(2) = 2e-23
 Identities = 51/110 (46%), Positives = 73/110 (66%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
           L  G  +P+   GT +       S++E  QAV  A+ AGYRHID AAVY +E  VG  I+
Sbjct: 8   LQSGAKMPLNGFGTWKA------SVEETEQAVTAALRAGYRHIDCAAVYWNEAAVGTAIS 61

Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLI 412
           +AI+ G+V RE+LF+T+K+WN  HA D+VV + ++SLK   +DY DL+L+
Sbjct: 62  KAISGGVVKREDLFITSKVWNTCHATDKVVDSCRQSLKDHQVDYFDLFLV 111



 Score = 29.1 bits (62), Expect(2) = 2e-23
 Identities = 14/38 (36%), Positives = 21/38 (55%)
 Frame = +2

Query: 488 DARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
           D   L L R IGVSN++   +   ++ + I+P  NQ E
Sbjct: 104 DYFDLFLVRDIGVSNYSVALLVDTLNYARIKPSVNQCE 141


>UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase;
           n=1; Rhodococcus sp. RHA1|Rep: Probable
           2,5-didehydrogluconate reductase - Rhodococcus sp.
           (strain RHA1)
          Length = 265

 Score =  110 bits (265), Expect = 2e-23
 Identities = 64/147 (43%), Positives = 87/147 (59%)
 Frame = +2

Query: 161 EVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR 340
           +  +AV   IEAGYR IDTA +Y +E+ VG  +AE    G V REELFVTTKL    H  
Sbjct: 18  DATRAVLSGIEAGYRLIDTATIYDNEDAVGVALAEC---G-VPREELFVTTKLRGSDHVS 73

Query: 341 DQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSI 520
             +  A++ SLK LGLD +DL+LIH+P+       P +  Y+  ++ M   R  GL R +
Sbjct: 74  GDIRGAVERSLKNLGLDRLDLFLIHWPL-------PRHNRYVAAFEAMLACRDAGLVRHV 126

Query: 521 GVSNFNATQITRLVSNSYIRPGXNQIE 601
           GVSNF  T + R+V+ +   P  NQI+
Sbjct: 127 GVSNFLETHLRRVVAETGESPAVNQIQ 153


>UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1;
           Phytophthora infestans|Rep: Aldo-keto reductase,
           putative - Phytophthora infestans (Potato late blight
           fungus)
          Length = 255

 Score =  110 bits (265), Expect = 2e-23
 Identities = 66/182 (36%), Positives = 100/182 (54%)
 Frame = +2

Query: 56  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235
           M+V  P   L  G  IP++ LG       +S+   E   A+  +++ GYRHIDTA +Y +
Sbjct: 1   MSVNVPTKILPSGARIPMIGLGV-----YQSEPGPETYNAILTSLKLGYRHIDTAEIYGN 55

Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415
           EE VG+    A+ +  + REE+FVTTKL+       + + A + S  +LG+ YI LYL+H
Sbjct: 56  EEDVGR----AVRDSGIPREEIFVTTKLFTTNWGYSKALAAGKASNDRLGIVYIYLYLLH 111

Query: 416 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQ 595
            P   K        +  +TW+ ++D R+    R IGVSNFN T +  L   ++I+P  NQ
Sbjct: 112 APGPPK--------ERADTWRAVEDLREQETLRDIGVSNFNETLLATLRKTAHIKPAVNQ 163

Query: 596 IE 601
           +E
Sbjct: 164 VE 165


>UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4;
           Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter
           sp. (strain FB24)
          Length = 287

 Score =  110 bits (264), Expect = 3e-23
 Identities = 66/181 (36%), Positives = 104/181 (57%)
 Frame = +2

Query: 59  AVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDE 238
           A   P ++L  G+TIP + LGT           DE   AV +A+++GYR +DTA  Y++E
Sbjct: 10  ASDIPRLKLPHGHTIPRLGLGTWPMLE------DECETAVRFALQSGYRLVDTAFQYRNE 63

Query: 239 EQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 418
           E VG+GI  A   G V R ELF+++K   + H+ D V  A  ESL+KLGLD++D+++ H+
Sbjct: 64  EAVGRGIRTA---G-VPRSELFISSKFNKESHSIDGVQRAYDESLRKLGLDHLDMFMCHW 119

Query: 419 PIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598
           P+       P    Y++ W+G+    + G  ++IGVSNF    +  ++  + + P  NQI
Sbjct: 120 PV-------PALGKYVDAWKGLVKLLEEGRVKAIGVSNFKPAHLKDIIDATGVVPDVNQI 172

Query: 599 E 601
           +
Sbjct: 173 Q 173


>UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein T08H10.1 - Caenorhabditis elegans
          Length = 333

 Score =  110 bits (264), Expect = 3e-23
 Identities = 65/187 (34%), Positives = 106/187 (56%), Gaps = 12/187 (6%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           I LN G  +P+  LGT +   K+     E+  A+  A++AGYR IDTA +YQ+E  +G+ 
Sbjct: 6   IPLNTGAQLPLFGLGTWQ--VKDEA---ELTVALRAALDAGYRLIDTAHLYQNEHIIGKV 60

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
           + E I++G + RE++FVT+KL    HA + V   ++  LK L L+YIDLYLIH P   K 
Sbjct: 61  LHEYISSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLYLIHCPFPFKH 120

Query: 437 DD------------SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 580
            +            +   I +++TW+ ++   + G  +++GVSNF+  Q+  L   + ++
Sbjct: 121 QEGSFAPLMENGELAVTEIAHIDTWRALEKLYKEGKLKALGVSNFSCNQLQALYDAAEVK 180

Query: 581 PGXNQIE 601
           P   Q+E
Sbjct: 181 PANQQVE 187


>UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several
           dehydrogenases of different specificities; n=4;
           Pezizomycotina|Rep: Similarity: shows similarity to
           several dehydrogenases of different specificities -
           Aspergillus niger
          Length = 381

 Score =  110 bits (264), Expect = 3e-23
 Identities = 69/194 (35%), Positives = 107/194 (55%), Gaps = 19/194 (9%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           + LN G  IP +  GT +          +V  AVY A++AGYRH+D A +YQ++ +V +G
Sbjct: 7   VTLNSGAQIPQLGFGTWQSAP------GQVGDAVYEALKAGYRHLDLATIYQNQREVAEG 60

Query: 257 IAEAIAN--GLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA- 427
           I  A  +  GL  RE++F+T+KLWN +H    V  AL E L +L LDY+DLYL+H+P++ 
Sbjct: 61  IKRAYKDVPGL-KREDIFITSKLWNSQHDPAVVEKALDECLAELELDYLDLYLVHWPVSF 119

Query: 428 -TKPDDSP---------------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRL 559
            T  +  P               D+I  ++TW+ M    +   AR++GVSN     +  +
Sbjct: 120 TTGSELFPLVKDSSVEGGDVVINDDISIVDTWKAMTQLPK-SKARTVGVSNHMIPHLEAI 178

Query: 560 VSNSYIRPGXNQIE 601
           ++ + + P  NQIE
Sbjct: 179 INATGVVPAVNQIE 192


>UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=3; Staphylococcus|Rep: Oxidoreductase,
           aldo/keto reductase family - Staphylococcus epidermidis
           (strain ATCC 35984 / RP62A)
          Length = 279

 Score =  109 bits (263), Expect = 4e-23
 Identities = 64/173 (36%), Positives = 100/173 (57%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
           LN+G  +P V LG      K +D  +++ + V  A++AGYR  DTA  Y +E+ +G    
Sbjct: 8   LNNGYPMPAVGLGV----YKIAD--EQMEEVVRTALDAGYRAFDTAYFYGNEKALGS--- 58

Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 442
            A+ +  V R+ELF+T+KLWND    DQ +    +SL  LGLDY+DL+LIH+P       
Sbjct: 59  -ALKHSNVERDELFITSKLWNDYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWPCEN---- 113

Query: 443 SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
             D + Y+E+++ ++   + G  ++IGV NF    + +L+  + I P  NQIE
Sbjct: 114 --DQL-YIESYKALEHLYEEGKIKAIGVCNFKIHHLEKLMKETKITPQVNQIE 163


>UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus
           djamor|Rep: Reductase AKOR2 - Pleurotus djamor
          Length = 306

 Score =  109 bits (263), Expect = 4e-23
 Identities = 72/191 (37%), Positives = 105/191 (54%), Gaps = 14/191 (7%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P I LN G  +P +ALG   G  +E  +  + ++    A+++GYRHIDTA +Y  E+ VG
Sbjct: 5   PPIVLNTGARMPALALGGWAGLTEEERT--QAKEWFLTALKSGYRHIDTAQIYYTEKSVG 62

Query: 251 QGIAEAIANGLVTREELFVTTKL-WNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427
             I E+   G + REELF+TTKL WN  H+R  V  + Q+SL+ LG +YIDLYL+HFP  
Sbjct: 63  NAIRES---G-IPREELFITTKLPWNH-HSR--VAESFQKSLENLGTEYIDLYLVHFPQR 115

Query: 428 TKPD---DSPDNID----------YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSN 568
              D   D P N D            + W  ++     G  ++IGVSN++   +  L+  
Sbjct: 116 VFYDETTDFPRNPDGSIKVVNSPTLNDVWADVETLLDTGKVKAIGVSNYSIKTLEELLKT 175

Query: 569 SYIRPGXNQIE 601
           + + P  NQ+E
Sbjct: 176 AKVVPAVNQVE 186


>UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose
           reductase; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to aldose reductase -
           Strongylocentrotus purpuratus
          Length = 274

 Score =  109 bits (261), Expect = 7e-23
 Identities = 58/147 (39%), Positives = 86/147 (58%)
 Frame = +2

Query: 161 EVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR 340
           +V  AV  AI+ GYRHID A VY +E +VG G+ E     +V RE++F+T+KLWN+KH  
Sbjct: 11  QVEAAVKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLWNNKHHP 70

Query: 341 DQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSI 520
           D V  A   +LK L L Y+DLYL+H+P+A               +Q M+     G  ++I
Sbjct: 71  DDVEQACDITLKNLQLSYVDLYLMHWPMA---------------YQAMEKLVTSGKCKAI 115

Query: 521 GVSNFNATQITRLVSNSYIRPGXNQIE 601
           G+SNF+   + R++  + I+P   Q+E
Sbjct: 116 GLSNFSMKMMKRVIEKATIQPANLQVE 142


>UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep:
           Lin2848 protein - Listeria innocua
          Length = 280

 Score =  109 bits (261), Expect = 7e-23
 Identities = 66/174 (37%), Positives = 103/174 (59%)
 Frame = +2

Query: 80  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259
           +LN+G  +P      G G  K +D    +R A+  A++ GYR  DTA+ Y +E+++G   
Sbjct: 10  RLNNGIEMP----RHGFGVYKLTDE-QRMRTALETAVDVGYRLFDTASFYHNEKELGDFF 64

Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 439
           A   ++GL  R+E FVTTK+WN +   D+ + A ++S KKL LD +DLYL+H+P   K D
Sbjct: 65  A---SSGL-KRDEFFVTTKMWNTEQGYDETLRAFEKSQKKLQLDQVDLYLVHWP---KQD 117

Query: 440 DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                  + ETW+ ++     GL R+IGVSNF A  + RL +++ + P  +Q+E
Sbjct: 118 ------TFFETWRAVEKLYDEGLVRAIGVSNFEAHHLDRLRTSANVLPVVDQLE 165


>UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes
           aegypti|Rep: Aldo-keto reductase - Aedes aegypti
           (Yellowfever mosquito)
          Length = 284

 Score =  109 bits (261), Expect = 7e-23
 Identities = 69/184 (37%), Positives = 108/184 (58%), Gaps = 2/184 (1%)
 Frame = +2

Query: 56  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235
           M+ +AP ++LN+G  +P++ LGT    +KE + ++ ++ A    I+AGYRHIDTA  YQ+
Sbjct: 1   MSPKAPMVKLNNGLEMPVLGLGTW--LSKEGEGVEAIKAA----IDAGYRHIDTAYFYQN 54

Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKL--WNDKHARDQVVPALQESLKKLGLDYIDLYL 409
           E++VG+ I   I  G+V RE+LFVTTK   W+ K+    ++P   ++  KL    +D   
Sbjct: 55  EKEVGEAIRAKIEEGVVCREDLFVTTKFIDWDTKN----LMP--YDADGKLQFSDVD--- 105

Query: 410 IHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGX 589
                            Y++TW+ M+   + G  +SIGVSNFN+ QITRL++   I+P  
Sbjct: 106 -----------------YIDTWKAMEKLLKTGKVKSIGVSNFNSEQITRLLAECEIKPVT 148

Query: 590 NQIE 601
           NQ+E
Sbjct: 149 NQVE 152


>UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1;
           Filobasidiella neoformans|Rep: Aldo-keto reductase,
           putative - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 303

 Score =  109 bits (261), Expect = 7e-23
 Identities = 64/175 (36%), Positives = 96/175 (54%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           ++++DGN IP   LG      KE+         V WA+EAGYRH+DTA  Y++E   G+ 
Sbjct: 33  LKMHDGNAIPQFGLGVYEMNDKET------YDCVKWALEAGYRHVDTAEWYENEAPCGKA 86

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
           IA+ +     +REE+F+T+KL N+  + +Q    L+ SLK+ G++Y DLYL+H  I    
Sbjct: 87  IADFLKATGTSREEIFLTSKLKNNS-SYEQAFVDLKGSLKRSGVEYFDLYLMHSAIG--- 142

Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
              P  +     W+ + DA+  GL +SIGVSNF    I   +      P  NQ++
Sbjct: 143 --GP--VIRKNVWKALCDAQSQGLVKSIGVSNFGKKHIQEFIDQKVPLPTVNQVD 193


>UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 700

 Score =  109 bits (261), Expect = 7e-23
 Identities = 70/176 (39%), Positives = 102/176 (57%), Gaps = 17/176 (9%)
 Frame = +2

Query: 125 GRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 304
           G GT K S   ++   AV  AI+ GYRHID A  Y++E+ V  GI +A   G V R +L+
Sbjct: 24  GFGTWKMSK--EQATPAVAHAIKTGYRHIDCAWAYRNEDAVAAGIKKA---G-VPRSQLW 77

Query: 305 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA----------------TKP 436
           +T+KLWN  H  + V  AL  SLK LG DY+DLYL+H+P+A                  P
Sbjct: 78  LTSKLWNSFHHPEHVEKALDASLKDLGTDYLDLYLMHWPVAFLNSKGSMVPSIRSTGGHP 137

Query: 437 DDSPD-NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
            +S D + D++ T++ M++  + G  R+IGVSNFN  + + +V  + I+P  NQ+E
Sbjct: 138 VESEDLSRDFMATYRVMEEMVKKGKVRNIGVSNFNIRRTSEVVDEASIKPVVNQVE 193


>UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto
           reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to aldo-keto reductase - Nasonia vitripennis
          Length = 353

 Score =  108 bits (260), Expect = 9e-23
 Identities = 76/214 (35%), Positives = 120/214 (56%), Gaps = 17/214 (7%)
 Frame = +2

Query: 11  SLLRIITLTCL-LNAAMAVQAPCI-QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYW 184
           S + + TL C+ ++ +  V+A  + +L+ G+  PIV LGT  G  +     D +   +  
Sbjct: 7   SFVLLATLCCVSISYSQNVEAGTVYRLSSGHNFPIVGLGT-HGLNE-----DVLETVLTG 60

Query: 185 AIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKL-WNDKHARDQVVPAL 361
           A+E G  HIDT+ VY++EE +G+ + +  A G   RE++FVT+KL + D H  + V   +
Sbjct: 61  ALEKGIGHIDTSFVYKNEETIGKVLKDWFAKG-GKREDIFVTSKLPYYDNHP-ESVEKYI 118

Query: 362 QESLKKLGLDYIDLYLIHFP-----------IATKPDDS---PDNIDYLETWQGMQDARQ 499
           + SL+KLGL Y+D+YLIH P           +AT  D S       D +  W+ M+   +
Sbjct: 119 KLSLEKLGLQYLDMYLIHAPFAVHHKEDSYELATNEDGSVVLDTQTDPIAVWKEMEKQVK 178

Query: 500 LGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
            G  +SIG+SNFN TQIT ++  + I+P   Q+E
Sbjct: 179 EGRTKSIGLSNFNETQITNILKEAKIKPSNLQVE 212


>UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9;
           Bacteria|Rep: 2,5-didehydrogluconate reductase -
           Arthrobacter sp. (strain FB24)
          Length = 291

 Score =  108 bits (259), Expect = 1e-22
 Identities = 70/191 (36%), Positives = 102/191 (53%), Gaps = 13/191 (6%)
 Frame = +2

Query: 68  APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247
           +P + LN+G  + I  LG G      +D+   V  A    +EAGYRH DTAA+Y +E  V
Sbjct: 4   SPRLSLNNG--VLIDQLGFGLYKVPPADAAGLVTMA----LEAGYRHFDTAAMYGNETGV 57

Query: 248 GQGIAE--AIANG-----------LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGL 388
           G+ I      A G            ++RE+LFVTTK+WND H  D  + A   S+  LG+
Sbjct: 58  GKAIGALAGFAGGGPAGGSGEAAPSLSREDLFVTTKVWNDDHGYDATMRAFDTSMSNLGM 117

Query: 389 DYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSN 568
           +Y+DLYLIH+P A +         + E+++ M+   + G  R+IGVSNF    +  L+  
Sbjct: 118 EYVDLYLIHWPCARRG-------LFTESYRAMETLYREGRIRAIGVSNFQPAHLEHLLET 170

Query: 569 SYIRPGXNQIE 601
           + + P  NQIE
Sbjct: 171 AEVVPAVNQIE 181


>UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;
           n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
           CG2767-PA - Nasonia vitripennis
          Length = 356

 Score =  107 bits (256), Expect = 3e-22
 Identities = 68/189 (35%), Positives = 108/189 (57%), Gaps = 14/189 (7%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           I+L+ G+ +P++ LGT +         + +  AV  A+E+GYRHIDTA  Y +EE +G+ 
Sbjct: 28  IKLSSGHDMPMIGLGTWQMPP------EAIEVAVTAALESGYRHIDTAFTYGNEEAIGKT 81

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA--- 427
           + +    G   RE+LF+TTKL       + V   L+ SL+KLGL+Y+++YLIH P A   
Sbjct: 82  LKKWFDKG-GKREDLFITTKLPPIGMRAEYVESYLKLSLEKLGLEYVNMYLIHKPFAFVK 140

Query: 428 ----TKPDDSPD-------NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 574
                +P  +PD       + D++  W+ M+   + G  RSIG+SNFN +Q+  +  ++ 
Sbjct: 141 DKYKYEPALNPDGSVVLDTDTDHVAIWRAMEKQVKAGRVRSIGLSNFNKSQLLNVYEHAE 200

Query: 575 IRPGXNQIE 601
           I+P   QIE
Sbjct: 201 IKPSNLQIE 209


>UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 -
           Mycoplasma gallisepticum
          Length = 289

 Score =  107 bits (256), Expect = 3e-22
 Identities = 61/159 (38%), Positives = 92/159 (57%)
 Frame = +2

Query: 125 GRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 304
           G GT K  D    V +AV  A+E GYRH+D A +Y+++  V QGI     +G V R+E+F
Sbjct: 26  GFGTYKLEDGKQTV-EAVKTALEVGYRHLDCAEIYENQLSVSQGIK---LSG-VNRKEIF 80

Query: 305 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 484
           +T+K+WND    +    A  + LK L L+Y+DL LIH+PI     D+   ++  +TW+ M
Sbjct: 81  ITSKIWNDDKGYESTKKAFHKILKDLDLEYLDLLLIHWPIGKGFKDNWQEVN-AQTWKAM 139

Query: 485 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
           ++    G  ++IG+SNF    I  L  ++ I P  NQ+E
Sbjct: 140 EEFYLEGKIKAIGLSNFLVHHIEALKKSAKILPMVNQLE 178


>UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome
           shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
           chr1 scaffold_22, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 360

 Score =  107 bits (256), Expect = 3e-22
 Identities = 68/185 (36%), Positives = 107/185 (57%), Gaps = 12/185 (6%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
           LN    IP + LGT +         D   +AV  A+  GYR ID A +Y +E +VG+ +A
Sbjct: 14  LNTKAKIPAIGLGTWQSGG------DLCVEAVKRALSEGYRQIDCAHLYGNEVEVGEALA 67

Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP------I 424
           EA  NG + RE++F+T+KL+   ++ +++  +++ SLK LG+ Y+DLYL+H+P       
Sbjct: 68  EAF-NGSLKREDVFLTSKLYCTMNSLNKIENSVRVSLKNLGVTYLDLYLMHWPDITAFGD 126

Query: 425 ATKP--DDSPDNIDYL----ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPG 586
           AT P  +   D+  +L    + W+ M+   +LGL R+IGVSNF   QI  L+  + I P 
Sbjct: 127 ATDPPSNSGNDHRQFLNRLKKAWKAMEGLIELGLVRAIGVSNFGVQQIKELLKFAKIVPA 186

Query: 587 XNQIE 601
            NQ++
Sbjct: 187 VNQVK 191


>UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8;
           Saccharomycetales|Rep: Probable oxidoreductase YJR096W -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 282

 Score =  107 bits (256), Expect = 3e-22
 Identities = 70/179 (39%), Positives = 103/179 (57%), Gaps = 5/179 (2%)
 Frame = +2

Query: 80  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259
           +L++G  IP +ALGT      ++  I      VY  ++ GYRH DTA +Y +E++VG GI
Sbjct: 7   KLSNGFKIPSIALGTYDIPRSQTAEI------VYEGVKCGYRHFDTAVLYGNEKEVGDGI 60

Query: 260 AEAIAN--GLVTREELFVTTKLWNDKHARDQVVPALQESLKKL-GLDYIDLYLIHFPIAT 430
            + +    G   REE+F TTKLWN ++   +   A+++ L ++ GL YIDL LIH P+  
Sbjct: 61  IKWLNEDPGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSPL-- 118

Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RPGXNQIE 601
             + S      LETW+ MQ+A   GL +SIGVSN+    I  L++   +  +P  NQIE
Sbjct: 119 --EGSKLR---LETWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWPELKHKPVVNQIE 172


>UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep:
           Aldo-keto reductase - Helicobacter hepaticus
          Length = 292

 Score =  106 bits (254), Expect = 5e-22
 Identities = 68/176 (38%), Positives = 98/176 (55%), Gaps = 4/176 (2%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
           LN+GN IP + LGT R      D++  V  AV  A + GYRHIDTA  Y +E    +G+ 
Sbjct: 17  LNNGNKIPKLGLGTWR----IDDNV--VEAAVREAFKVGYRHIDTAQAYGNE----RGVG 66

Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 442
           EA+    + REELF+T+K+  +         ++  SLK + LD+IDL LIH P   +P +
Sbjct: 67  EAVRKSKIKREELFITSKIRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSP---QPWN 123

Query: 443 SPDNIDY----LETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598
           S    DY    +E +  ++DA++ G  RSIGVSNF    +  ++ N   +P  NQI
Sbjct: 124 SFRKGDYFKENVEVYNALEDAQKAGKVRSIGVSNFLQKDLENILKNCKTKPAANQI 179


>UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1;
           Klebsiella pneumoniae|Rep: Putative uncharacterized
           protein - Klebsiella pneumoniae
          Length = 279

 Score =  106 bits (254), Expect = 5e-22
 Identities = 65/175 (37%), Positives = 102/175 (58%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           I LNDG  +P    G      ++ DS+  +RQA    ++AG+RH DTA  Y +E+ VG+ 
Sbjct: 6   ILLNDGYYMPRPGCGLWLIDNRDVDSL--IRQA----LKAGFRHFDTAQAYFNEDGVGR- 58

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
              A+    V RE+LF+T+K+        + + +  E+L++LG++Y++L+LIH+PI  K 
Sbjct: 59  ---ALRYTEVPREQLFITSKIRGRDMGYARTLVSFNETLERLGVEYLELFLIHWPIPAK- 114

Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                N+ Y+ETW+   +    GL RSIGVSNF    I RL+ ++ + P  NQ+E
Sbjct: 115 -----NL-YVETWEASIELEASGLIRSIGVSNFTCQHIERLIEDTGVVPAVNQLE 163


>UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2;
           Gammaproteobacteria|Rep: Aldo/keto reductase -
           Pseudoalteromonas atlantica (strain T6c / BAA-1087)
          Length = 273

 Score =  106 bits (254), Expect = 5e-22
 Identities = 55/136 (40%), Positives = 86/136 (63%)
 Frame = +2

Query: 158 DEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHA 337
           D+ + AV  A++ GYRHIDTA  Y++E +VG    +AI+   ++R ELFVTTK+W D  +
Sbjct: 24  DDAKLAVENALDVGYRHIDTAQAYENEAEVG----DAISASKISRGELFVTTKVWFDNLS 79

Query: 338 RDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARS 517
            D+ + ++Q SL +L  DY+DL L+H+P    PD+     +YL+    ++  ++ GL R 
Sbjct: 80  ADKFITSVQNSLTQLNTDYVDLLLVHWP---SPDNKVSMAEYLKE---LKACKERGLTRH 133

Query: 518 IGVSNFNATQITRLVS 565
           IGVSNF  +Q+   +S
Sbjct: 134 IGVSNFTQSQLDEALS 149


>UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3;
           Bacteria|Rep: Putative uncharacterized protein -
           Bacteroides capillosus ATCC 29799
          Length = 287

 Score =  106 bits (254), Expect = 5e-22
 Identities = 65/175 (37%), Positives = 100/175 (57%), Gaps = 2/175 (1%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
           L++G +IP V    G GT K  D    V      AI  GYRH DTA+ Y  E  +GQ +A
Sbjct: 10  LSNGLSIPAV----GFGTYKTGDGDSAVLSN---AIAQGYRHFDTASFYGTETALGQAVA 62

Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 442
           E+     + RE+ F+T+KLW  +   D  + A   +L++LG DY+DLYLIH+P   +PD 
Sbjct: 63  ESD----IPREDFFLTSKLWKTEMGYDAALRAFDATLERLGTDYLDLYLIHWP---RPDL 115

Query: 443 SPDNIDYL--ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
             ++   L  ETW+ ++   + GL R+IGVSNF    +  +++++ + P  +Q+E
Sbjct: 116 ELEDWAKLDRETWRALERLYESGLVRAIGVSNFLPHHLEPILASANVAPMVDQLE 170


>UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus
           coagulans 36D1|Rep: Aldo/keto reductase - Bacillus
           coagulans 36D1
          Length = 273

 Score =  106 bits (254), Expect = 5e-22
 Identities = 59/172 (34%), Positives = 97/172 (56%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
           L +G  IP + LGT +    E+        AV +A++ GYRHIDTA  Y +EE VG+   
Sbjct: 10  LENGVAIPKIGLGTWQVPNGET-----TYHAVSFALKNGYRHIDTAYAYHNEESVGK--- 61

Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 442
            A+ +  + R ++FVT+KL  +  + D+ +    E++   GL+ +DLYLIH P       
Sbjct: 62  -AVRDSGIDRRDIFVTSKLPAEIKSYDKALKTFDETMGNFGLEQLDLYLIHAPWPWSEKG 120

Query: 443 SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598
           +    + +E W+ M++  + G  R+IGVSNF+ + +  ++ N+ I+P  NQI
Sbjct: 121 ADYTKENIEVWKAMEEIYESGRCRAIGVSNFSVSDLKAVMENAKIKPMVNQI 172


>UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 -
           Trichoderma atroviride (Hypocrea atroviridis)
          Length = 327

 Score =  106 bits (254), Expect = 5e-22
 Identities = 66/189 (34%), Positives = 102/189 (53%), Gaps = 16/189 (8%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
           LN G  IP V    G GT     +  E   AV  A++ GYRH+D A  Y +E++VG  I 
Sbjct: 17  LNTGAKIPAV----GFGTFANEGAKGETYAAVTKALDVGYRHLDCAWFYLNEDEVGDAIR 72

Query: 263 EAIANGL-VTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 439
           + +A    VTR++LF+ TK+WN  H  + V  + + S + L +DYIDL+L+H+PIA + +
Sbjct: 73  DFLARRPDVTRKDLFICTKVWNHLHEPEDVKWSAKNSCENLKVDYIDLFLVHWPIAAEKN 132

Query: 440 D------SPDNIDYLE---------TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 574
                   PD    +          TW+ M++    G+ ++IGVSN+    + +L+  + 
Sbjct: 133 ADRTVKIGPDGKYVINKALTENPEPTWRAMEELVDSGIVKAIGVSNWTIPGLKQLLEFAR 192

Query: 575 IRPGXNQIE 601
           I+P  NQIE
Sbjct: 193 IKPAVNQIE 201


>UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep:
           Aldo/keto reductase - Mesorhizobium sp. (strain BNC1)
          Length = 308

 Score =  105 bits (253), Expect = 6e-22
 Identities = 60/148 (40%), Positives = 87/148 (58%)
 Frame = +2

Query: 158 DEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHA 337
           DE   AV  A+  GYRHIDTAA Y +E +VG+GI  A   G + R+E+F+ TK+W   + 
Sbjct: 42  DETTAAVEEALRLGYRHIDTAAAYGNEREVGEGIRRA---G-IARDEVFIETKIWISDYG 97

Query: 338 RDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARS 517
            D+ + A  +S  KLG+D IDL L+H P+ +  D +      L  ++ ++     G  R+
Sbjct: 98  YDETLHAFDKSAGKLGVDQIDLLLLHQPLPSAFDRT------LGAYRALEKLLADGKVRA 151

Query: 518 IGVSNFNATQITRLVSNSYIRPGXNQIE 601
           IGVSNF    +TRL++ + I P  NQIE
Sbjct: 152 IGVSNFMPEHLTRLLTETSIVPAVNQIE 179


>UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1;
           Actinomyces odontolyticus ATCC 17982|Rep: Putative
           uncharacterized protein - Actinomyces odontolyticus ATCC
           17982
          Length = 292

 Score =  105 bits (253), Expect = 6e-22
 Identities = 65/185 (35%), Positives = 101/185 (54%)
 Frame = +2

Query: 47  NAAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAV 226
           NA  +   P   L  G+ IP++  GT +  A E D+ D V +A    +E GYRHIDTA +
Sbjct: 9   NAPASSPIPTFMLPTGSPIPVLGFGTYK-VAPE-DTYDAVSRA----LEVGYRHIDTAQM 62

Query: 227 YQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLY 406
           Y +E +VG  +    A+G + RE+LF+TTK+ N  H  D+   +++ SL+ L  DY+DL 
Sbjct: 63  YGNEAEVGAALE---ASG-IAREDLFITTKVDNSNHEPDRAAASIRRSLEDLRTDYVDLL 118

Query: 407 LIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPG 586
           L+H+P+ T         D    W  ++DA   G AR+IG+SN+    +  +   + + P 
Sbjct: 119 LVHWPLPTLYGG-----DVALPWPALEDAFNAGGARAIGLSNYEREHVEAVREVATVAPH 173

Query: 587 XNQIE 601
             Q+E
Sbjct: 174 VLQVE 178


>UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1;
           Clostridium beijerinckii NCIMB 8052|Rep:
           2,5-didehydrogluconate reductase - Clostridium
           beijerinckii NCIMB 8052
          Length = 289

 Score =  105 bits (252), Expect = 8e-22
 Identities = 56/148 (37%), Positives = 83/148 (56%)
 Frame = +2

Query: 158 DEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHA 337
           ++   AV  AI+ GYRH DTA +Y +E+ +G     AI    + REE F+T+K+WN  H 
Sbjct: 30  EDFETAVGEAIKIGYRHFDTAKIYGNEKDLGL----AIEKSQIPREEFFITSKVWNTDHG 85

Query: 338 RDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARS 517
            +    A +++ KKL ++Y+D+YLIHF  +           YLETW  M++    G  + 
Sbjct: 86  YEATKKAFEQTCKKLNVEYLDMYLIHFASSY----------YLETWHAMEELYLQGKIKV 135

Query: 518 IGVSNFNATQITRLVSNSYIRPGXNQIE 601
           IGV+NF    +  L+ +S I P  NQIE
Sbjct: 136 IGVANFQIQHLEELMKHSRITPMINQIE 163


>UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;
           n=91; Proteobacteria|Rep: 2,5-diketo-D-gluconic acid
           reductase B - Yersinia pestis
          Length = 267

 Score =  105 bits (252), Expect = 8e-22
 Identities = 62/146 (42%), Positives = 90/146 (61%)
 Frame = +2

Query: 98  TIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIAN 277
           +IP+  LGT R   ++   ID V QA    +  GYR IDTA +Y++E  VGQ I E+  N
Sbjct: 2   SIPVFGLGTFR--LQDQIVIDSVSQA----LTLGYRAIDTAQIYENEAPVGQAIQESGIN 55

Query: 278 GLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNI 457
               R+ELF+TTK+W    ++D+++P+L+ES++KL  DY+DL LIH+P    P+   D +
Sbjct: 56  ----RDELFITTKIWIANLSKDKLIPSLRESIQKLKTDYVDLTLIHWP---SPN---DEV 105

Query: 458 DYLETWQGMQDARQLGLARSIGVSNF 535
              E    +  A+ LGL R IG+SNF
Sbjct: 106 SVAEFMSELLKAKGLGLTRQIGISNF 131


>UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1
           protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo
           sapiens "AKR1B1 protein. - Takifugu rubripes
          Length = 330

 Score =  104 bits (250), Expect = 1e-21
 Identities = 54/118 (45%), Positives = 73/118 (61%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P + LN G  +P++ LGT     K    +    +AV  AI AGYRHIDTA VY++E +VG
Sbjct: 3   PSVTLNTGALMPVLGLGTW----KSGKGV--TTEAVKVAIGAGYRHIDTAYVYENETEVG 56

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424
            G+   I  G+V REELF+ +KLW   H    V  A +++L  L LDY+DLYL+HFP+
Sbjct: 57  AGVQAMIDQGVVKREELFIVSKLWCTFHTPSLVRGACEKTLSSLNLDYVDLYLMHFPM 114



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 21/53 (39%), Positives = 34/53 (64%), Gaps = 2/53 (3%)
 Frame = +2

Query: 449 DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RPGXNQIE 601
           D   +L+TW+ M++    GLA++IG+SNFN  QI  +++   +  +P  NQIE
Sbjct: 158 DGTSFLDTWEAMEELVDDGLAKAIGISNFNKDQIEAVLNKPGLKHKPATNQIE 210


>UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 339

 Score =  104 bits (250), Expect = 1e-21
 Identities = 74/199 (37%), Positives = 102/199 (51%), Gaps = 17/199 (8%)
 Frame = +2

Query: 56  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235
           MA   P   LN G  +P V +G  +G        +E+  A+  AI+ GYRH+DTA  Y++
Sbjct: 1   MAANIPSFTLNTGAKLPSVGMGCWQGQPGPGRD-NELVDALVRAIKVGYRHLDTATGYRN 59

Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415
           E +VGQ    A+    V R E+FVTTKL       D VV  L+ SL +LG+DYIDL+L+H
Sbjct: 60  EAEVGQ----AVRQSGVARSEIFVTTKL-RPGGVHD-VVQELENSLNELGIDYIDLWLLH 113

Query: 416 FPIATKPDDSP---------DNIDYL-----ETWQGMQDA---RQLGLARSIGVSNFNAT 544
           +P     DD           ++  +L     ETW  M+D       G  ++IGVSNF+  
Sbjct: 114 WPQGFTKDDGGFGTGESFGLEHQKHLGPTFNETWAKMEDVFLNSHKGKVKAIGVSNFSIK 173

Query: 545 QITRLVSNSYIRPGXNQIE 601
            +  L   S + P  NQIE
Sbjct: 174 NLEILAKTSKVTPAVNQIE 192


>UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2;
           Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter
           sp. (strain FB24)
          Length = 281

 Score =  104 bits (249), Expect = 2e-21
 Identities = 67/177 (37%), Positives = 97/177 (54%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P + LN+G  IP +  G  +   +E+  I E       A+EAGYRHIDTAA Y++E  VG
Sbjct: 10  PQLTLNNGVKIPQLGFGVFQVPPEETQRIVED------ALEAGYRHIDTAAAYRNEAGVG 63

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430
             I+   A+G + RE++F+TTKL N +        A Q S K LG++++DLYLIH+P+  
Sbjct: 64  AAIS---ASG-IPREDIFITTKLRNGEQGNAH--EAFQNSRKALGVEFVDLYLIHWPV-- 115

Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                P    Y E W+ M+        R+IGVSNF    +  L+  + + P  NQ+E
Sbjct: 116 -----PSQGLYTEAWKAMEKLYANSQIRAIGVSNFLGEHLDTLLPAADVVPAVNQVE 167


>UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n=1;
           Rhizobium leguminosarum bv. viciae 3841|Rep: Putative
           aldo-keto reductase/oxidase - Rhizobium leguminosarum
           bv. viciae (strain 3841)
          Length = 274

 Score =  103 bits (247), Expect = 3e-21
 Identities = 60/133 (45%), Positives = 82/133 (61%)
 Frame = +2

Query: 152 SIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDK 331
           S DE  Q V WA+EAG RHIDTA  Y +E+ V +GI +A   G V R E+F+TTK+  D 
Sbjct: 21  SADEAHQGVIWALEAGCRHIDTAQGYGNEQDVARGIKDA---G-VARNEIFITTKVKPDN 76

Query: 332 HARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLA 511
           +    V+P+++ESL+KL +D +DL L+H+P    P +     DYL  +  + D+   GLA
Sbjct: 77  YGPGAVMPSVRESLEKLRVDQVDLLLLHWP---SPHNKYPLADYLGQFAEVFDS---GLA 130

Query: 512 RSIGVSNFNATQI 550
           R IGVSNF    I
Sbjct: 131 RQIGVSNFTKAMI 143


>UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1;
           Parvularcula bermudensis HTCC2503|Rep: Putative
           uncharacterized protein - Parvularcula bermudensis
           HTCC2503
          Length = 278

 Score =  103 bits (247), Expect = 3e-21
 Identities = 63/156 (40%), Positives = 93/156 (59%)
 Frame = +2

Query: 104 PIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGL 283
           PI  LG G    +  D+    R +   AIE GYRHID AA+Y++E++VG+GI ++   G 
Sbjct: 10  PIPRLGFGTWQLEGEDA----RTSTRTAIETGYRHIDGAAIYKNEKKVGEGIKDS---G- 61

Query: 284 VTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDY 463
           + R+ELFVTTK+WN+   + +   A+ ESL +LGLDY++L L+H+PI   P    D +  
Sbjct: 62  IPRDELFVTTKIWNEDIQKGRHSEAVDESLDRLGLDYVNLILLHWPINDMP--IADQVGP 119

Query: 464 LETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 571
           L       + ++ G A+ IG+SN+N  Q    VS S
Sbjct: 120 L------AEIKRSGRAKLIGISNYNQAQFLEAVSAS 149


>UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep:
           Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 287

 Score =  103 bits (246), Expect = 4e-21
 Identities = 62/179 (34%), Positives = 102/179 (56%), Gaps = 2/179 (1%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P ++L  G  +P++ LGT     K  D  ++++Q+V  A++AGYR  DTAAVY +E  +G
Sbjct: 4   PSVRLMSGTQMPLLGLGT----YKLQDH-EQLKQSVSCALQAGYRAFDTAAVYGNEAHLG 58

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP--I 424
           Q + E +    + RE++F+ +KL    H        L+ SL++L  +YIDLYLIH+P   
Sbjct: 59  QVLKELLPKYGLIREDVFIISKLAPSDHGLRAKEGCLR-SLEQLDCEYIDLYLIHWPGME 117

Query: 425 ATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
              P+DS  +    ++W  +++    G  ++IGVSN+ A  I  L+++  + P   QIE
Sbjct: 118 GLDPEDSRHSEYRAQSWATLEEFHASGQFKAIGVSNYTAKHIRELLASCRVPPAVLQIE 176


>UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1;
           Lactobacillus acidophilus|Rep: Reductase-dehydrogenase -
           Lactobacillus acidophilus
          Length = 271

 Score =  103 bits (246), Expect = 4e-21
 Identities = 69/176 (39%), Positives = 91/176 (51%), Gaps = 3/176 (1%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
           LN+G  IP + LGT         + DEV + V  A+  GYR  DTA  Y +E  VG+GI 
Sbjct: 9   LNNGEKIPQIQLGTWL------INNDEVNKVVRQAVNIGYRGFDTAKDYGNESGVGKGIW 62

Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP---IATK 433
               N  + R ++F+TTKL       +    A+  +L K GL+YIDL LIH P   I   
Sbjct: 63  ----NSDIERSDIFLTTKLPTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQPWIEVN 118

Query: 434 PDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
             +       LE W+ M++A + G  RSIGVSNF    I  +V+N  I P  NQIE
Sbjct: 119 RTNDRHFKGNLENWRAMEEAVKAGKVRSIGVSNFLQEDIENIVNNGTITPAVNQIE 174


>UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1;
           Parabacteroides merdae ATCC 43184|Rep: Putative
           uncharacterized protein - Parabacteroides merdae ATCC
           43184
          Length = 301

 Score =  103 bits (246), Expect = 4e-21
 Identities = 72/185 (38%), Positives = 99/185 (53%)
 Frame = +2

Query: 47  NAAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAV 226
           NA    + P ++LN+G  +P   LG G    K     D   + V  AI+ G+R IDTA  
Sbjct: 22  NAQEMNKVPTVKLNNGMEMP--QLGVGTFLVK-----DNAAERVCHAIKVGFRLIDTAQG 74

Query: 227 YQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLY 406
           Y +E++VG+GI  +   G + R ELF+TTK+   +     V  +L +SL  LG DYIDL 
Sbjct: 75  YGNEKEVGEGICRS---G-IDRRELFITTKVNTMEMRGGTVRQSLDKSLADLGTDYIDLV 130

Query: 407 LIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPG 586
           LIH+P+              ETWQ +++    G  RSIGVSNFN   +  L+  + IRP 
Sbjct: 131 LIHWPVKG---------HIKETWQILEEYVDKGKIRSIGVSNFNPHHLDELLEYARIRPV 181

Query: 587 XNQIE 601
            NQIE
Sbjct: 182 VNQIE 186


>UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3;
           Saccharomycetales|Rep: Conjugated polyketone reductase
           C1 - Candida parapsilosis (Yeast)
          Length = 304

 Score =  103 bits (246), Expect = 4e-21
 Identities = 66/192 (34%), Positives = 109/192 (56%), Gaps = 10/192 (5%)
 Frame = +2

Query: 56  MAVQAPCIQLNDGNTIPIVALGTGRGTAKE--SDSIDEVRQAVYWAIEAGYRHIDTAAVY 229
           M++     +L++GN IP VA GTG    K   +D   ++   +  A+ +G+RHID A +Y
Sbjct: 1   MSLAGKEFKLSNGNKIPAVAFGTGTKYFKRGHNDLDKQLIGTLELALRSGFRHIDGAEIY 60

Query: 230 QDEEQVGQGIAEAIANGLVTREELFVTTKL------WNDKHARDQ-VVPALQESLKKLGL 388
              +++G     A+ N  + R+++F+T K       ++ KH++ Q    AL+  L+ LGL
Sbjct: 61  GTNKEIGI----ALKNVGLNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLGL 116

Query: 389 DYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV-S 565
           +Y+DLYLIHFP  +   +     D +E W+ ++ A+  GLAR+IGVSNF    +  ++ +
Sbjct: 117 EYVDLYLIHFPYIS---EKSHGFDLVEAWRYLERAKNEGLARNIGVSNFTIENLKSILDA 173

Query: 566 NSYIRPGXNQIE 601
           N+   P  NQIE
Sbjct: 174 NTDSIPVVNQIE 185


>UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5;
           Saccharomycetales|Rep: D-arabinose dehydrogenase -
           Pichia stipitis (Yeast)
          Length = 326

 Score =  102 bits (245), Expect = 6e-21
 Identities = 67/194 (34%), Positives = 105/194 (54%), Gaps = 21/194 (10%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
           L++G TIP + LGT        +   E+++ V  A++AGYRHIDTA  Y  EE +GQ + 
Sbjct: 12  LSNGKTIPALGLGT-----VPPEDPHELKEQVITAVKAGYRHIDTAWYYGTEEYIGQALK 66

Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA----- 427
           +    G+V RE+LF+TTK+W       +   +L +SL  LGLDY+DL+L H+P+      
Sbjct: 67  QLFEEGIVKREDLFITTKVWPSFWRNPE--KSLDKSLADLGLDYVDLFLQHWPVVLHGDE 124

Query: 428 ----TKP---------DDSP-DNIDYLETWQGMQDAR-QLGLARSIGVSNFNATQITRLV 562
                +P         DD P   I Y++ +  ++D        +SIGVSN++  ++ +L+
Sbjct: 125 NGLPPQPRDKDGKLIYDDDPVSGIKYIDAYHSLEDIMDNTSKVKSIGVSNYSIPKLRKLL 184

Query: 563 SN-SYIRPGXNQIE 601
           +     +P  NQIE
Sbjct: 185 AAVRKHKPVVNQIE 198


>UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia
           ATCC 50803
          Length = 313

 Score =  102 bits (244), Expect = 8e-21
 Identities = 55/163 (33%), Positives = 93/163 (57%), Gaps = 15/163 (9%)
 Frame = +2

Query: 158 DEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI--ANGLVTREELFVTTKLWNDK 331
           + V+ AV  A+  GYRHID A VYQ+EE +G+   +    A+  + RE++++T+KLWN  
Sbjct: 17  EAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKREDVWITSKLWNYN 76

Query: 332 HARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPD-------------NIDYLET 472
           H  + V    ++++  L +DY+DL+L+H+P+A   +D  D              +   +T
Sbjct: 77  HRPELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEGRAMLEKVPLADT 136

Query: 473 WQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
           W+ M+   + GL + IGVSN+    +  L++ + I+P  NQIE
Sbjct: 137 WRAMEQLVEEGLVKHIGVSNYTVPLLADLLNYAKIKPLVNQIE 179


>UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 297

 Score =  102 bits (244), Expect = 8e-21
 Identities = 58/177 (32%), Positives = 100/177 (56%), Gaps = 3/177 (1%)
 Frame = +2

Query: 80  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259
           +LN G  IP V  GT + T       + V  A+  A+ AGYR  DTA  Y +E+++G+ +
Sbjct: 14  KLNSGYNIPFVGFGTYKVTG------ENVPPAIDAALTAGYRMFDTAKYYLNEKELGEAL 67

Query: 260 AEAIANGLVTREELFVTTKLW-NDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
              +    ++R ++F+T+K +   K+ R+     ++ESL+ L  DYID+YL+H+P     
Sbjct: 68  KILLPKHGLSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYPKPNDS 127

Query: 437 D-DSPDNIDYLE-TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
           D D  +N +Y +  ++ +++A+  G  RSIGVSN+    +  L + + + P  NQ+E
Sbjct: 128 DNDDVNNAEYRKIAYEVLEEAKAAGKVRSIGVSNYEIVHLEELKTYAKVPPCANQLE 184


>UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6;
           n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 -
           Apis mellifera
          Length = 292

 Score =  101 bits (243), Expect = 1e-20
 Identities = 62/177 (35%), Positives = 96/177 (54%), Gaps = 4/177 (2%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
           L+ G  +P++  GT +   +E      V Q V  ++  G+R IDTA  Y++EE +G  + 
Sbjct: 10  LSSGYDMPLIGFGTYKIQGREL-----VYQVVDESLNVGFRSIDTAVGYRNEEDIGYALK 64

Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQ-VVPALQESLKKLGLDYIDLYLIHFPIATK-P 436
             +    + R ++F+TTKL    +   + +   +Q+SLK     YIDLYLIH+P AT+ P
Sbjct: 65  NLLPKYNLQRSDIFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYLIHWPGATRIP 124

Query: 437 DDSPDNIDY-LETWQGMQDARQLGLARSIGVSNFNATQITRLVSN-SYIRPGXNQIE 601
           + S +N     +TW  + D ++ G  RSIGVSNF    +  L+ N   I P  NQ+E
Sbjct: 125 ETSTNNPSLRAKTWNKLVDLKKQGFIRSIGVSNFTIKHLQELLQNCKDILPAVNQVE 181


>UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 286

 Score =  101 bits (243), Expect = 1e-20
 Identities = 72/188 (38%), Positives = 103/188 (54%), Gaps = 6/188 (3%)
 Frame = +2

Query: 56  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235
           MA      +L +G+T+P + LGT +G     D  ++V+  V  AI+AGYRHID AA Y +
Sbjct: 1   MATPTASFRLVNGSTLPAIGLGTFQG----DDGNEKVKNIVKAAIQAGYRHIDGAAAYGN 56

Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415
           EE +G  I E   +G ++R+EL    + W   H    V  AL  SL+ LGL+Y+      
Sbjct: 57  EEAIGDAIKE---SG-ISRDEL---AQPW---HEPKDVERALDLSLEALGLEYV------ 100

Query: 416 FPIATKPDDSPDNID------YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 577
            P A  P   P+N+D      Y ETWQ M+     G A++IG+SNFN  +  R++  + I
Sbjct: 101 -PHAYLP--GPNNVDYERSRKYTETWQAMEKLVDSGKAKAIGLSNFNILKTKRILEIARI 157

Query: 578 RPGXNQIE 601
           RP  NQ+E
Sbjct: 158 RPAVNQVE 165


>UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;
           n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA
           - Apis mellifera
          Length = 321

 Score =  101 bits (241), Expect = 2e-20
 Identities = 63/188 (33%), Positives = 103/188 (54%), Gaps = 13/188 (6%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           I L +G  +PI+  GT +   KE      +  A+  A+EAGYRHIDTA  Y++E+ +G  
Sbjct: 6   ILLPNGELMPIIGFGTWQAQEKE------LEDALNIALEAGYRHIDTATSYENEKVIGDV 59

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK- 433
           +     +  + R ++F+ TKL    +  + V   ++ SL+ L L+Y+DLYLIH PI  + 
Sbjct: 60  LKNWFDSKKLKRSDIFIVTKLPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLIHVPIGFEK 119

Query: 434 ------PDDSPDNI------DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 577
                 P D   +I      +++E W  M+   + G  ++IG+SNFN +QI R++ N+ +
Sbjct: 120 VGDILHPFDENGHIRLDNSTNHVEIWAEMEKQVKCGRTKAIGLSNFNISQIKRILKNTKM 179

Query: 578 RPGXNQIE 601
           +    QIE
Sbjct: 180 KISMLQIE 187


>UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5;
           Trypanosomatidae|Rep: Aldo-keto reductase-like protein -
           Leishmania major strain Friedlin
          Length = 372

 Score =  100 bits (240), Expect = 2e-20
 Identities = 62/180 (34%), Positives = 90/180 (50%), Gaps = 18/180 (10%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           I + D +TIP +  GT R        + E   AV +A+  GYRH+D A  Y +E  VG+ 
Sbjct: 22  IAMRDSHTIPQLGFGTYRLP------VSEATDAVAFALSCGYRHVDCAKAYGNEAAVGEA 75

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
           +A+A+      RE+LFVT+KLW      D V  A + +L  L LDY+DLYLIH+P+  + 
Sbjct: 76  LAQALRTRCTRREDLFVTSKLWPTDQHPDHVEAACRATLAALQLDYLDLYLIHWPVCMRH 135

Query: 437 ---------------DDSP---DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 562
                          D +P    ++  L+TW  M      GL +SIG++N     +  LV
Sbjct: 136 TPHWTSDEDRYPRHRDGTPAIDTSVTLLDTWTAMNRLVDRGLVKSIGLANCTTAHVNDLV 195


>UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto
           reductase family 1, member B10, partial; n=1; Macaca
           mulatta|Rep: PREDICTED: similar to aldo-keto reductase
           family 1, member B10, partial - Macaca mulatta
          Length = 275

 Score =  100 bits (239), Expect = 3e-20
 Identities = 61/164 (37%), Positives = 93/164 (56%), Gaps = 8/164 (4%)
 Frame = +2

Query: 134 TAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTT 313
           T K    + +V++AV  AI+AGYRHID A VYQ+E +VG+ I E I    V RE+LF+ +
Sbjct: 38  TRKPKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVS 97

Query: 314 K------LWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETW 475
           K      LW     R  V  A +++LK L L Y+D+YLIH+P               + +
Sbjct: 98  KVHMAHWLWTTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWP---------------QGF 142

Query: 476 QGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RPGXNQIE 601
           + M++    GL +++G+SNFN  QI +L++   +  +P  NQ+E
Sbjct: 143 KAMEELVDEGLVKALGISNFNHFQIEKLLNKPGLKYKPVTNQVE 186


>UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 320

 Score =  100 bits (239), Expect = 3e-20
 Identities = 61/177 (34%), Positives = 98/177 (55%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P ++L  G  +P +A GTG      SD+  +V  A    +++G+R ID A VY +E  +G
Sbjct: 4   PTVRLASGLELPRLAFGTGTALYN-SDAAKQVTMA----LDSGFRFIDGAEVYANEASMG 58

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430
            GI   +A+  + R +++V TK+   K     +  A++  L+KL +D +D YL+H P   
Sbjct: 59  AGIESFLASSGLKRNDIYVLTKV--GKEGMKDLQSAIKVELQKLKVDQLDSYLLHLPPRG 116

Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
           + D  P N+D    W+ ++  +Q GL +SIGVSN+ A+ I +L+      P  NQIE
Sbjct: 117 Q-DGLPSNVD---AWKELEKIKQAGLTKSIGVSNWLASDIQQLLDAGLSVPDINQIE 169


>UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Rep:
           YvgN - Bacillus sp. NRRL B-14911
          Length = 268

 Score =   99 bits (238), Expect = 4e-20
 Identities = 63/181 (34%), Positives = 95/181 (52%), Gaps = 6/181 (3%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAV---YWAIEAGYRHIDTAAVYQDEEQV 247
           I LN+G  +PIV  GT     + +D   ++   +     AIE GYR ID A +Y++EE V
Sbjct: 4   ITLNNGLEMPIVGTGTNTYGKENNDYNGDLTNEIPELASAIELGYRSIDAAIMYRNEELV 63

Query: 248 GQGIAEAIANGLVTREELFVTTKLWNDKH---ARDQVVPALQESLKKLGLDYIDLYLIHF 418
           G  +AE+     V REE F+TTK+   +    +++    A+  SLK    DY+DL LIHF
Sbjct: 64  GSVLAES----KVPREEFFITTKIPASEEYISSKEATRAAIDNSLKNFQTDYLDLLLIHF 119

Query: 419 PIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598
           PI        D +    TW+  ++  + G  ++IGVSNF    +  L   + ++P  NQI
Sbjct: 120 PIE-------DKVQLKNTWEVFEEYYEAGKLKAIGVSNFEENHLDELKEFAKVKPAVNQI 172

Query: 599 E 601
           +
Sbjct: 173 Q 173


>UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 355

 Score = 85.8 bits (203), Expect(2) = 4e-20
 Identities = 56/143 (39%), Positives = 82/143 (57%), Gaps = 13/143 (9%)
 Frame = +2

Query: 212 DTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLD 391
           D A +Y +E +VGQGI    A+G V R ELFVTTK+W   H + +    L ESL++LGLD
Sbjct: 80  DAAWIYGNENEVGQGIK---ASG-VPRSELFVTTKIWCTYHRQPEA--CLDESLQRLGLD 133

Query: 392 YIDLYLIHFPIA-TKPDDS--PDNIDYL----------ETWQGMQDARQLGLARSIGVSN 532
           Y+DL L+H+P+   K  D   P N D            +TW+ M+     G  ++IGVSN
Sbjct: 134 YVDLLLVHWPVPLVKRGDEKIPLNEDGSRAIDRDWSPEQTWELMEKLPATGKTKAIGVSN 193

Query: 533 FNATQITRLVSNSYIRPGXNQIE 601
           ++   + +L++ + I P  NQ+E
Sbjct: 194 WSIAFLDKLLAKAKIVPAANQVE 216



 Score = 34.7 bits (76), Expect(2) = 4e-20
 Identities = 20/44 (45%), Positives = 26/44 (59%)
 Frame = +2

Query: 80  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHI 211
           +LN G  IP++ LGT +          EV +AV  AI+AGYRHI
Sbjct: 15  KLNTGAEIPVIGLGTWQSAP------GEVAKAVESAIKAGYRHI 52


>UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 287

 Score = 99.5 bits (237), Expect = 5e-20
 Identities = 57/171 (33%), Positives = 98/171 (57%), Gaps = 2/171 (1%)
 Frame = +2

Query: 95  NTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI- 271
           N +P++ +GT +   +E      +RQ +    + GYR IDTA VY +E ++G+ + + + 
Sbjct: 9   NNMPLIGIGTWQVQKEEI-----LRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEKLLP 63

Query: 272 ANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPD 451
           ANGL  RE++++T+KL        +   +++ESL  L ++Y+DL LIH+P ++   ++P 
Sbjct: 64  ANGL-KREDIWITSKLAPSNAGVKKARESIEESLSNLKVEYLDLLLIHWPGSSLKSENPA 122

Query: 452 NIDY-LETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
           N    +E+W  M +    G  RS+GVSNF    +  L  +S + P  NQ+E
Sbjct: 123 NKKLRVESWNVMCEMMAEGKLRSVGVSNFEICHLEELKKDSNVVPAVNQVE 173


>UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain
           CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
           lipolytica|Rep: Yarrowia lipolytica chromosome B of
           strain CLIB122 of Yarrowia lipolytica - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 302

 Score = 99.5 bits (237), Expect = 5e-20
 Identities = 63/179 (35%), Positives = 100/179 (55%), Gaps = 2/179 (1%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDE--VRQAVYWAIEAGYRHIDTAAVYQDEEQ 244
           P ++L++G  IP +  G+G    +     +E  +  AV  AI AG+ HIDTA  Y  E+Q
Sbjct: 4   PKVKLSNGLEIPAIGFGSGTKWKRPPGEKEERELIDAVVSAINAGHLHIDTAEFYGTEKQ 63

Query: 245 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424
           +G+ I E+   G V R+++F+T+K      A D  + ++   LK L  DY DL+LIH P 
Sbjct: 64  IGEAIKES---G-VPRKDIFLTSKTLFGLLA-DDPIESISNQLKTLQTDYFDLFLIHVP- 117

Query: 425 ATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
              P+D   N D  + W  ++   + GLA++IGVSN +  ++  ++  + I+P  NQIE
Sbjct: 118 ---PNDDI-NYDLAKAWGVLEQLYEKGLAKAIGVSNHSPAELETIIKVAKIKPHVNQIE 172


>UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:
           ENSANGP00000029046 - Anopheles gambiae str. PEST
          Length = 331

 Score = 99.1 bits (236), Expect = 7e-20
 Identities = 63/188 (33%), Positives = 101/188 (53%), Gaps = 14/188 (7%)
 Frame = +2

Query: 80  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259
           +LN G  IP+   GT +   +E      + Q + +A+EAGYRHIDTA VY++EE +G  +
Sbjct: 35  KLNTGFDIPLAGFGTYQIHGQEL-----IYQVLDYALEAGYRHIDTAVVYRNEEYIGTAL 89

Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPAL-QESLKKLGLDYIDLYLIHFP-IATK 433
              +    + RE++F+T+KL +     +  V  + ++SL  L  DY+DLYLIH+P ++ K
Sbjct: 90  KTLLPKYNLKREDIFITSKLISQSGKDEAFVEQMVRKSLANLQTDYLDLYLIHWPGVSGK 149

Query: 434 ----------PDDSPDNIDY-LETWQGMQDARQLGLARSIGVSNFNATQITRLVSN-SYI 577
                         PDN+ Y   +W  +    + G  RSIGVSN+    +  ++++   I
Sbjct: 150 CGRWKWLFGMQVTHPDNVKYRAASWNALSKLEREGCLRSIGVSNYTVKHLKEMLADCKGI 209

Query: 578 RPGXNQIE 601
            P  NQ+E
Sbjct: 210 VPAVNQVE 217


>UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas
           mobilis|Rep: Putative oxidoreductase - Zymomonas mobilis
          Length = 273

 Score = 98.7 bits (235), Expect = 9e-20
 Identities = 61/175 (34%), Positives = 93/175 (53%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           + LNDG+++P +  G  +    +++S+      V    + GYR +DTAA Y++EE VG+G
Sbjct: 7   VVLNDGHSMPAIGQGVYQLNPAQAESM------VALGYDLGYRAVDTAAWYENEEGVGEG 60

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
           +    A         F+TTKL      R     AL +S++ LG+  ++LYLIH+P     
Sbjct: 61  LRSRHARS-------FITTKLMPQDMGRVNCFVALDKSIRNLGVTSLNLYLIHWP----- 108

Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
               D   Y ETWQ +   R +G A SIGVSNF    +  ++++S + P  NQIE
Sbjct: 109 --GQDRKRYEETWQTLIQIRAIGKASSIGVSNFTIDHLDHIIADSGVVPAVNQIE 161


>UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8;
           Gammaproteobacteria|Rep: Aldo/keto reductase -
           Shewanella sp. (strain ANA-3)
          Length = 280

 Score = 98.7 bits (235), Expect = 9e-20
 Identities = 60/160 (37%), Positives = 91/160 (56%), Gaps = 3/160 (1%)
 Frame = +2

Query: 95  NTIPIVA---LGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAE 265
           N  P+ A   LGTG    K++ + D    AV  A+E G RHIDTA +Y +E+ VG    +
Sbjct: 10  NQAPLTAMPMLGTGTFRLKDNAAFD----AVLMALEEGSRHIDTAQIYGNEQAVG----D 61

Query: 266 AIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDS 445
           AI    + REELF+TTK+W +   +++   ++ +SL  L   Y+DL LIH+P+ +   D 
Sbjct: 62  AINTSGIPREELFITTKVWTENLTKERFETSVIDSLTALQTKYLDLLLIHWPLNS---DE 118

Query: 446 PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVS 565
           P  ++YL   + + D    GL R IGVSNF   Q+ + ++
Sbjct: 119 PSMVEYLSELKAVLDK---GLTRRIGVSNFTNAQLAQAIA 155


>UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=2; Streptococcus agalactiae|Rep:
           Oxidoreductase, aldo/keto reductase family -
           Streptococcus agalactiae H36B
          Length = 245

 Score = 98.3 bits (234), Expect = 1e-19
 Identities = 65/173 (37%), Positives = 98/173 (56%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
           LN+G  IP +    G G  +  D + E  Q+V  A++ GYR IDTA+ Y +EE VG+   
Sbjct: 9   LNNGVKIPSL----GFGVFQIDDPL-ECEQSVLDALQVGYRLIDTASGYLNEEAVGR--- 60

Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 442
            AI    + R+E+FV TKLW    + ++  PA+  +LK+L LDYI+LYLIH P+      
Sbjct: 61  -AIKKSGIPRKEIFVVTKLWIQDASEEKAGPAIDRALKRLQLDYINLYLIHQPMG----- 114

Query: 443 SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                DY    + ++ A +   A +IGVSNF+  ++  L+ ++ I P  NQI+
Sbjct: 115 -----DYYGACRALEKAYEERKALAIGVSNFSNGRVQDLILHNKIIPAVNQIQ 162


>UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765
           - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 288

 Score = 97.9 bits (233), Expect = 2e-19
 Identities = 60/181 (33%), Positives = 101/181 (55%), Gaps = 4/181 (2%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P + LN+   +P++ LGT R   +E     +   AV  A++AGYR  DTAAVY++E  +G
Sbjct: 6   PSVLLNNDIQMPLLGLGTFRLQGQE-----DTYSAVDAALKAGYRAFDTAAVYRNEAHLG 60

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP--- 421
             +   +    ++RE++F+T+KL   K    +     Q+SL++LGL YIDLYLIH+P   
Sbjct: 61  HALRCLLPKHGLSREDVFITSKL-GPKDQGSKARNGCQKSLEQLGLGYIDLYLIHWPGTQ 119

Query: 422 -IATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598
            +      +P+N    ++W+ +++    G  R+IGVSN+    +  L+ +  + P   Q+
Sbjct: 120 GLPVGDKRNPEN--RAQSWRVLEEFYSEGKFRAIGVSNYTVEHMQELLKSCKVPPAVLQV 177

Query: 599 E 601
           E
Sbjct: 178 E 178


>UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10;
           Alphaproteobacteria|Rep: Aldo/keto reductase -
           Mesorhizobium sp. (strain BNC1)
          Length = 274

 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/170 (37%), Positives = 96/170 (56%)
 Frame = +2

Query: 92  GNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI 271
           G TIP +    G G  + SD+  EV + +  A+EAG+RH DTA +YQ+E  +G+ +  A 
Sbjct: 8   GATIPAL----GFGVFRMSDA--EVERIIPAALEAGFRHFDTAQIYQNEAALGRALERAG 61

Query: 272 ANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPD 451
           A     RE+LF+TTK+W D ++ D+   ++ ESL+KL +D +DL L+H+P    P  +  
Sbjct: 62  AR----REDLFLTTKVWVDNYSADKFAASVDESLEKLKVDQVDLLLLHWPAHEVPVAA-- 115

Query: 452 NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
               +E    ++DA   G  R IGVSN N  Q+   ++ S      NQ+E
Sbjct: 116 ---QIERLNAVKDA---GKTRFIGVSNQNIAQMRESIARSAAPIVTNQVE 159


>UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4;
           Catarrhini|Rep: Isoform 2 of Q96JD6 - Homo sapiens
           (Human)
          Length = 263

 Score = 97.1 bits (231), Expect = 3e-19
 Identities = 49/102 (48%), Positives = 64/102 (62%)
 Frame = +2

Query: 131 GTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 310
           G +    S  +V +AV  AI+AGYRH D A  Y +E +VG GI   I  G V RE+LF+ 
Sbjct: 8   GLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIA 67

Query: 311 TKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
           TKLW   H +  V  A ++SLK L L+Y+DLYLIH+P+  KP
Sbjct: 68  TKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109


>UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona
           intestinalis|Rep: Aldo-keto reductase 1a - Ciona
           intestinalis (Transparent sea squirt)
          Length = 584

 Score = 97.1 bits (231), Expect = 3e-19
 Identities = 66/180 (36%), Positives = 101/180 (56%), Gaps = 14/180 (7%)
 Frame = +2

Query: 65  QAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 244
           + P ++LN G  +P + LGT R  +K  +++         A++ GYR +DTA +Y  E++
Sbjct: 256 EIPDVKLNSGYMMPPIGLGTARLFSKTYETVKT-------ALKLGYRMLDTAQIYTGEDK 308

Query: 245 VG-------QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDL 403
           +        + I  AIA+  V R ELF+ TKL  +   ++  +  ++ESLKKL  DYIDL
Sbjct: 309 INNFKVSSEEEIGRAIADSDVPRSELFIVTKLAPESMEKENAIAKVEESLKKLRTDYIDL 368

Query: 404 YLIH-FPIATK--PDDS--PD--NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 562
            LIH F ++T   PDD+  P+  N  +L  W+ M++ +  GL RSIGVSN     +  LV
Sbjct: 369 LLIHDFYMSTACGPDDTDLPECKNNPFL-AWKTMEEMQAKGLVRSIGVSNIYIEDLQYLV 427


>UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like
           protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase
           family 1 member C-like protein 2 - Homo sapiens (Human)
          Length = 320

 Score = 97.1 bits (231), Expect = 3e-19
 Identities = 49/102 (48%), Positives = 64/102 (62%)
 Frame = +2

Query: 131 GTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 310
           G +    S  +V +AV  AI+AGYRH D A  Y +E +VG GI   I  G V RE+LF+ 
Sbjct: 8   GLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIA 67

Query: 311 TKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
           TKLW   H +  V  A ++SLK L L+Y+DLYLIH+P+  KP
Sbjct: 68  TKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109


>UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1;
           Aspergillus terreus NIH2624|Rep: Putative
           uncharacterized protein - Aspergillus terreus (strain
           NIH 2624)
          Length = 301

 Score = 96.7 bits (230), Expect = 4e-19
 Identities = 74/207 (35%), Positives = 100/207 (48%), Gaps = 33/207 (15%)
 Frame = +2

Query: 80  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259
           +L+ G  +P V LGT      E      V  AV  A+  GYRHID AA Y +E +VG G 
Sbjct: 8   KLSSGYDMPAVGLGTWLSKPHE------VENAVETALRLGYRHIDAAACYLNENEVGNGW 61

Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYL---------- 409
            ++   G V R+++F+T+KLWN  H  D V  A+ ++LK L  DY+DLYL          
Sbjct: 62  KKS---G-VPRDQIFITSKLWNTHHHPDHVEEAVNKTLKDLQTDYLDLYLVFPSLLVLIH 117

Query: 410 ----------IHFPIATK-------PDDSPD------NIDYLETWQGMQDARQLGLARSI 520
                     IH+P+A +       P D         NI   +TW  ++     G  RSI
Sbjct: 118 DLLSLLTNNKIHWPVAFEHTNETLTPIDPVSKRFRLANIPIADTWAALEKLVDAGKVRSI 177

Query: 521 GVSNFNATQITRLVSNSYIRPGXNQIE 601
           GVSNF   +I  L+  + I P  NQIE
Sbjct: 178 GVSNFTIEKIEELLKTARIPPAVNQIE 204


>UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus
           niger|Rep: Putative frameshift - Aspergillus niger
          Length = 357

 Score = 96.7 bits (230), Expect = 4e-19
 Identities = 71/185 (38%), Positives = 104/185 (56%), Gaps = 12/185 (6%)
 Frame = +2

Query: 83  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
           LN G  IP  ALG G  T ++ DS +E    V   ++ G R IDTA VY  E+QVG+GI 
Sbjct: 40  LNTGAKIP--ALGVG--TFQDPDSQEET---VCQVLQRGMRLIDTARVYGVEQQVGRGIK 92

Query: 263 EAIANGLVTREELFVTTKLW-NDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK-- 433
           ++   G V REE+F+ TKLW ND H  D V  A+ +SL+ L   Y+DL L+H+P   K  
Sbjct: 93  KS---G-VPREEIFLGTKLWCNDFHP-DDVERAVDDSLRDLYTPYVDLLLMHYPCTFKRG 147

Query: 434 ----PDDSPDNI-----DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPG 586
               P D+   +      +++TW+ ++   + G  R+IGVSNF+  +I  L+  +   P 
Sbjct: 148 EDRFPRDAEGRMIHGETTFVDTWRALEKVVKTGKVRAIGVSNFSKGEIETLLRETSTVPA 207

Query: 587 XNQIE 601
            +Q+E
Sbjct: 208 VHQME 212


>UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep:
           Oxidoreductase - Bradyrhizobium japonicum
          Length = 272

 Score = 96.3 bits (229), Expect = 5e-19
 Identities = 62/171 (36%), Positives = 94/171 (54%)
 Frame = +2

Query: 89  DGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEA 268
           +G  IP + LGT   + +    + E       A+  GYRHIDTA VY +E +VG G+   
Sbjct: 7   NGARIPAIGLGTWELSGRPCARVVEQ------ALRLGYRHIDTAQVYDNEREVGDGVR-- 58

Query: 269 IANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSP 448
            A+G V R+++F+TTK+W +  A + +  +++ESL +L L  +DL L+H+P         
Sbjct: 59  -ASG-VRRDDVFLTTKVWTNHFAPNDLERSVKESLARLRLPSVDLLLLHWP--------N 108

Query: 449 DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
            ++   ET   +  ARQ+GL R IGVSNF    I + V+ S      NQ+E
Sbjct: 109 SHVPLAETLGALSHARQMGLTRHIGVSNFTVALIEQAVALSPEPLVCNQVE 159


>UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto
           reductase family - Caulobacter crescentus (Caulobacter
           vibrioides)
          Length = 279

 Score = 95.9 bits (228), Expect = 7e-19
 Identities = 62/182 (34%), Positives = 98/182 (53%)
 Frame = +2

Query: 56  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235
           M+   P ++  D   + + ALG G    +   ++  V +A    +E GYRHIDTA +Y +
Sbjct: 1   MSKLVPAVRSGD---VLMPALGFGTWQLENGTAVPLVEKA----LEIGYRHIDTAQIYGN 53

Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415
           E  VG     AI N  V R+E+F+TTK+W D+ A   +  + ++SL+KLG+D +DL L+H
Sbjct: 54  ERDVGA----AIRNSGVKRDEIFLTTKVWIDQFADGDLQRSAEKSLEKLGVDQVDLLLLH 109

Query: 416 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQ 595
           +P   KP+     +   ET + +   R  G  R+IG+SNF + Q+      S      +Q
Sbjct: 110 WP---KPE-----VPLAETLKALNAVRAKGWTRAIGLSNFPSAQLEEAAKLSEAPIATDQ 161

Query: 596 IE 601
           +E
Sbjct: 162 VE 163


>UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3;
           Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis
           alexandrii HTCC2633
          Length = 275

 Score = 95.9 bits (228), Expect = 7e-19
 Identities = 58/159 (36%), Positives = 87/159 (54%)
 Frame = +2

Query: 125 GRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 304
           G GT +  D  ++  + V  A++ GYRHIDTA +Y +E  VG G  ++   G V RE+ F
Sbjct: 16  GFGTWQLED--EDAARGVATALKTGYRHIDTAQIYGNEAAVGDGWKQS---G-VKREDFF 69

Query: 305 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 484
           +TTK+W DK     +  +++ESL KL  DY+DL L+H+P+   P          ET + M
Sbjct: 70  LTTKVWRDKFRDGDLQASVKESLDKLKTDYVDLLLLHWPVPEVP--------IAETMKAM 121

Query: 485 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
            + ++ G  R IGVSNF    +    ++S      NQ+E
Sbjct: 122 NEVKEAGQVRHIGVSNFTVDLLDEARAHSGAPLVANQVE 160


>UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family;
           n=1; Haloarcula marismortui|Rep: Oxidoreductase
           aldo/keto reductase family - Haloarcula marismortui
           (Halobacterium marismortui)
          Length = 274

 Score = 95.9 bits (228), Expect = 7e-19
 Identities = 62/155 (40%), Positives = 84/155 (54%)
 Frame = +2

Query: 92  GNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI 271
           G ++P + LGT + T +        R+ V  A+  GYRHIDTA  Y +E QVG G+  A 
Sbjct: 8   GTSVPALGLGTWQLTGQSC------RETVETALGMGYRHIDTAQAYGNERQVGLGMDAAA 61

Query: 272 ANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPD 451
               V RE++F+TTKL         V  + +ESL KLG DY+DL LIH+P      ++P 
Sbjct: 62  ----VDREDVFLTTKLDGSNRDERSVRRSTRESLNKLGTDYLDLLLIHWP------NTPW 111

Query: 452 NIDYLETWQGMQDARQLGLARSIGVSNFNATQITR 556
                ET   M D  + GL R IGVSNF+ + + R
Sbjct: 112 MASLSETLGAMNDVVEEGLVRHIGVSNFSPSLLDR 146


>UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15;
           Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B -
           Bradyrhizobium sp. (strain ORS278)
          Length = 273

 Score = 95.1 bits (226), Expect = 1e-18
 Identities = 59/159 (37%), Positives = 87/159 (54%)
 Frame = +2

Query: 125 GRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 304
           G GT +   ++   R AV  A+  GYRHIDTA +Y +E+ +G  +A A     + RE+L 
Sbjct: 15  GLGTFRMQGTV--CRDAVESALALGYRHIDTAEMYANEDAIGAALAAA----QIAREDLH 68

Query: 305 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 484
           VTTK+W +  A D +  A   SLKKL LD++DLYLIH+P AT        ++     + +
Sbjct: 69  VTTKVWPENLAPDAIRRAFDTSLKKLRLDFVDLYLIHWP-AT-------GMNLPAAMETL 120

Query: 485 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
              +Q G  R+IGV+NF    + + V +       NQ+E
Sbjct: 121 MALKQEGRTRAIGVANFTVALLKQAVEDIQAPVACNQVE 159


>UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma
           penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
          Length = 285

 Score = 94.7 bits (225), Expect = 2e-18
 Identities = 57/175 (32%), Positives = 96/175 (54%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           I+L +G  +PI+ LG  +   +  ++   + +A+    + GYR IDTA VY +EE VG  
Sbjct: 4   IKLANGLHMPIIGLGVYKAEGENCENT--IIKAID---DYGYRMIDTAQVYFNEEFVGNA 58

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
           I +      + RE++F+TTK+W   +  +  + ++ +SLKKL  +YIDL L+H P     
Sbjct: 59  IKQT----KIKREDIFITTKVWISNYGYNNTMYSISKSLKKLQTNYIDLVLLHQPFG--- 111

Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                  DY   W+ ++   + G+ ++IGVSNF A ++     +  ++P  NQIE
Sbjct: 112 -------DYYSAWKALEVLYKKGIVKAIGVSNFEADRLVDFCLHVDVKPVINQIE 159


>UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1;
           Helicobacter hepaticus|Rep: Putative uncharacterized
           protein - Helicobacter hepaticus
          Length = 270

 Score = 94.7 bits (225), Expect = 2e-18
 Identities = 61/175 (34%), Positives = 92/175 (52%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           + LN+G  +PI+ LGT   T K        ++A+  AIE GYR  D+A +Y +E ++G  
Sbjct: 4   LTLNNGVKMPILGLGTYSLTGKAG------QKAMSEAIEVGYRLFDSAQMYNNEAELGAA 57

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
           I  A+  G + REE F+ TKL  +  + D    ++++SLK LGLDYID  LIH P +   
Sbjct: 58  INAAVKGG-IKREEFFIQTKLL-ESSSEDLAKKSIEKSLKTLGLDYIDSLLIHMPYSQSK 115

Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                       ++ M+   + G+ R IG+SNF A   +  V +  + P  NQ E
Sbjct: 116 ----------AMYRAMESFYKQGILRVIGISNFGAKAYSEFVKSCEVIPAINQCE 160


>UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide
           reductase; n=4; Saccharomycetales|Rep: NADPH-dependent
           alpha-keto amide reductase - Saccharomyces cerevisiae
           (Baker's yeast)
          Length = 312

 Score = 94.3 bits (224), Expect = 2e-18
 Identities = 63/179 (35%), Positives = 93/179 (51%), Gaps = 6/179 (3%)
 Frame = +2

Query: 83  LNDGNTIPIVAL-GTGRGTAK--ESD---SIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 244
           LN+GN IP +A+ GTG    K  E+D   S   V Q VY     G  HID A +Y+   +
Sbjct: 10  LNNGNKIPAIAIIGTGTRWYKNEETDATFSNSLVEQIVYALKLPGIIHIDAAEIYRTYPE 69

Query: 245 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424
           VG+    A++     R  +F+T K        D     L  +LKK+G DY+DLYL+H P 
Sbjct: 70  VGK----ALSLTEKPRNAIFLTDKYSPQIKMSDSPADGLDLALKKMGTDYVDLYLLHSPF 125

Query: 425 ATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
            +K     + +   E W+ M+   + G A++IGVSNF    + R++  + ++P  NQIE
Sbjct: 126 VSK---EVNGLSLEEAWKDMEQLYKSGKAKNIGVSNFAVEDLQRILKVAEVKPQVNQIE 181


>UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1;
           Saccharopolyspora erythraea NRRL 2338|Rep:
           2,5-diketo-D-gluconic acid reductase - Saccharopolyspora
           erythraea (strain NRRL 23338)
          Length = 159

 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 57/117 (48%), Positives = 71/117 (60%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P + LN+G  +P   LG G     E    DE   AV  A+EAGYR IDTAA Y +E  VG
Sbjct: 5   PTVTLNNGVEMP--QLGYGVFQVPE----DETAAAVGAALEAGYRSIDTAAAYGNEAAVG 58

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 421
           + +A    +GL  R+ELFVTTKLWN     D  + A   SL+ LGLD++DLYLIH+P
Sbjct: 59  RALA---GSGLA-RDELFVTTKLWNADQGYDNALRAFDTSLELLGLDHLDLYLIHWP 111


>UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7;
           Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 -
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 349

 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 70/207 (33%), Positives = 113/207 (54%), Gaps = 33/207 (15%)
 Frame = +2

Query: 80  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259
           +L  G+ IP V LGT R  ++ + ++      V   +E GYRHIDTA  Y D+ +VGQGI
Sbjct: 17  RLLSGHKIPAVGLGTWRSGSQAAHAV------VTAIVEGGYRHIDTAWEYGDQREVGQGI 70

Query: 260 AEAIANGL---------------VTREELFVTTKLWN-----------DKHARDQVVPAL 361
             A+  GL               + R+ + +++ L N            + + ++V PAL
Sbjct: 71  KRAMHAGLERRDLFVTSKLWYTLILRKMINLSSPLMNVLVGTCLNKRCTELSPERVRPAL 130

Query: 362 QESLKKLGLDYIDLYLIHFPI-----ATKPDDSPDNIDY-LE-TWQGMQDARQLGLARSI 520
           Q +LK+L L+Y+DLYLIH+PI     A+KP  + D +D+ +E  W+ M++  +  L R+I
Sbjct: 131 QNTLKELQLEYLDLYLIHWPIRLREGASKPPKAGDVLDFDMEGVWREMENLSKDSLVRNI 190

Query: 521 GVSNFNATQITRLVSNSYIRPGXNQIE 601
           GV NF  T++ +L+  + + P   Q+E
Sbjct: 191 GVCNFTVTKLNKLLGFAELIPAVCQME 217


>UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter
           cryohalolentis K5|Rep: Aldo/keto reductase -
           Psychrobacter cryohalolentis (strain K5)
          Length = 282

 Score = 93.5 bits (222), Expect = 4e-18
 Identities = 62/169 (36%), Positives = 94/169 (55%), Gaps = 2/169 (1%)
 Frame = +2

Query: 101 IPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANG 280
           IP++ LGT + T +  D ID V Q     +  GY HIDTA  Y +E +VG+GI +   +G
Sbjct: 16  IPVLGLGTWQSTGQ--DCIDVVSQG----LRMGYEHIDTAQAYGNEVEVGKGIKQ---SG 66

Query: 281 LVTREELFVTTKLWND--KHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDN 454
            V R++ F+TTK++ D  K   +++V A + SL+ L  DY+DL L+H+P         D 
Sbjct: 67  -VARDKFFLTTKIFPDDMKFEPEKLVAAAKRSLENLDTDYVDLLLLHWP--------DDR 117

Query: 455 IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
           +   ET   + + ++ GL R+IGVSNFN   I      + +    NQ+E
Sbjct: 118 VPLSETIPALCELQKQGLTRNIGVSNFNIANIIEAKRYADVPIVVNQVE 166


>UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 264

 Score = 93.5 bits (222), Expect = 4e-18
 Identities = 61/175 (34%), Positives = 93/175 (53%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           + LNDG  +P+  LG  R    E+   D       +A++ GYR +DTA +YQ+E++VG  
Sbjct: 13  VTLNDGRKMPLFGLGVFR---LETGCED----VCLFALKNGYRMLDTADIYQNEKEVGSA 65

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
           + ++   GL  RE+++VTTKL   +      +   +ES+KKL + Y+DL+LIH P     
Sbjct: 66  VRKS---GL-KREDIYVTTKLKPSEEGHSNALKYAKESIKKLDIGYVDLFLIHTP----- 116

Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
              P NI  +  +  +   ++ GL RS+GVSNF    +  L       P  NQIE
Sbjct: 117 --RPGNI--IAAYDALLTLKEEGLIRSVGVSNFGVHHLEELRKAGCRTPAINQIE 167


>UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Rep:
           ABL209Cp - Ashbya gossypii (Yeast) (Eremothecium
           gossypii)
          Length = 310

 Score = 93.5 bits (222), Expect = 4e-18
 Identities = 63/178 (35%), Positives = 95/178 (53%), Gaps = 4/178 (2%)
 Frame = +2

Query: 80  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259
           +L+DG  IP V LG  + + +       V+  VY A+E GYR  D+A  Y +E+ V +GI
Sbjct: 14  RLSDGTQIPSVGLGVYQVSEQT------VQDLVYEALEVGYRLFDSAQAYHNEDGVARGI 67

Query: 260 AEAIANGL-VTREELFVTTKLWNDKHARDQVVPALQESLKKLG-LDYIDLYLIHFPIATK 433
           A  + +     RE+++ TTK+    H  +    +L++SL   G L YIDL L+H P++  
Sbjct: 68  AAWLKHAPGRRREDVYFTTKINTQNHGYEATKKSLEKSLHAAGPLGYIDLVLVHAPMS-- 125

Query: 434 PDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV--SNSYIRPGXNQIE 601
                D    L TWQ +++A   G  RSIGVSN+    ++ L+      IRP  NQ+E
Sbjct: 126 -----DRTRRLGTWQALEEAVVEGQVRSIGVSNYGQQHLSELLGWEGLKIRPVVNQVE 178


>UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 289

 Score = 93.5 bits (222), Expect = 4e-18
 Identities = 62/177 (35%), Positives = 92/177 (51%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P ++L DGN IP+       G       + ++ +AV   IE G+ H+D A +Y  EE+V 
Sbjct: 4   PLLRLRDGNQIPL-----DLGDTTFGQGLVDLTKAV---IEKGFYHLDCAEMYGTEEEV- 54

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430
              A AI    V RE+LF+T K+       D +  A+ +SL+K+  +Y DLYLIH P   
Sbjct: 55  ---AIAIKESGVPREKLFITNKV---AQGIDDIEAAIDQSLQKMQTNYFDLYLIHIPFFA 108

Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
           K ++     D+   W+ M+  ++ G ARSIGVSN+    I   +  +   P  NQIE
Sbjct: 109 KSEE-----DFQRAWKTMEGIQKAGKARSIGVSNYMRPHIEATLKGATSPPVTNQIE 160


>UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum
           lacusprofundi ATCC 49239|Rep: Aldo/keto reductase -
           Halorubrum lacusprofundi ATCC 49239
          Length = 309

 Score = 93.5 bits (222), Expect = 4e-18
 Identities = 65/181 (35%), Positives = 99/181 (54%), Gaps = 1/181 (0%)
 Frame = +2

Query: 62  VQAPCIQLNDGNTIPIVALGTGRGTAKESDSI-DEVRQAVYWAIEAGYRHIDTAAVYQDE 238
           V  P   L  G+T+P + LGT    A + D I D VR A    + +GY HIDTA  Y +E
Sbjct: 32  VTIPTQTLPSGDTLPALGLGT---YALDDDQIADSVRAA----LSSGYTHIDTAEGYHNE 84

Query: 239 EQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 418
           E +G+ +AE        R+++F+T+K+       + ++ + + SL++L  DY+DLYLIH+
Sbjct: 85  EAIGEVLAE------YDRDDVFLTSKVLAKNLGYESLIQSCEASLERLETDYLDLYLIHW 138

Query: 419 PIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598
           P       +P  I   E+ Q M +    GL R++GVSNF+A Q++     S +    NQI
Sbjct: 139 P-------NP-AISLRESLQAMAELHDRGLVRNVGVSNFSAYQLSCANHISEVPIAVNQI 190

Query: 599 E 601
           E
Sbjct: 191 E 191


>UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome.
           precursor; n=1; Aspergillus niger|Rep: Contig An01c0460,
           complete genome. precursor - Aspergillus niger
          Length = 351

 Score = 92.3 bits (219), Expect = 8e-18
 Identities = 70/189 (37%), Positives = 92/189 (48%), Gaps = 21/189 (11%)
 Frame = +2

Query: 98  TIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIAN 277
           T P V LGT +G A        V++AV  A+  GYRHIDTA  Y +E +VG    EAI  
Sbjct: 45  TFPAVGLGTFQGDAGNRG----VKEAVLQALRCGYRHIDTATAYGNEIEVG----EAIKE 96

Query: 278 GLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDY-IDLYLIHFPIATKP---DDS 445
             + REE+ VTTKL    H    V  AL  SL++L L+Y + ++L      + P      
Sbjct: 97  SRIPREEIIVTTKLAQTWHRVSDVERALDLSLERLQLNYGLSMHLYSASSYSVPHAYSPG 156

Query: 446 PDN-----------------IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 574
           PDN                  DY  TW  M+     G  + IGVSNFN  ++ RL+ ++ 
Sbjct: 157 PDNNTIRHPNGKPIIDHELSRDYPSTWAAMESLVDKGKLKMIGVSNFNILKLERLLGSAR 216

Query: 575 IRPGXNQIE 601
           I P  NQIE
Sbjct: 217 IPPAVNQIE 225


>UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,
           isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG6084-PA, isoform A - Tribolium castaneum
          Length = 493

 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 59/177 (33%), Positives = 97/177 (54%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P  +LN+G  IP+       G A   D  +   + V   + + YR +D  +++++E++ G
Sbjct: 9   PIAKLNNGIEIPVF------GLAAPQDFFEV--ENVQLVVSSNYRLMD-CSIFENEKRFG 59

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430
             + + I  G + R++LF+ +K     +  + V  AL ++LKKL + Y+DLYLI  P A 
Sbjct: 60  VALQQLIEGGKIRRKDLFLMSKFCCT-NTTNLVKAALLDTLKKLQVAYLDLYLIERPPAC 118

Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
           K  +       +ETW+ M+      L R+IG+SNFN+ QI R++ N  IRP  NQI+
Sbjct: 119 KDHN------LIETWEAMEGLYSEKLTRAIGLSNFNSKQIERILENCTIRPQVNQIQ 169



 Score = 77.0 bits (181), Expect = 3e-13
 Identities = 39/91 (42%), Positives = 57/91 (62%), Gaps = 12/91 (13%)
 Frame = +2

Query: 365 ESLKKLGLDYIDLYLIHFPIATKPDDS------------PDNIDYLETWQGMQDARQLGL 508
           ESLK L LDY+D+YL+H+P A K   S            P ++D+++TW+ M+   +  L
Sbjct: 271 ESLKNLQLDYLDVYLMHWPHALKEGPSLHPIDPKTGLFIPSDVDFVDTWKAMEKMHEKDL 330

Query: 509 ARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
            +SIG+SNFN+ QI RL+ ++ I P  NQIE
Sbjct: 331 TKSIGISNFNSNQIDRLLKSAKIAPVINQIE 361


>UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 313

 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 61/188 (32%), Positives = 94/188 (50%), Gaps = 6/188 (3%)
 Frame = +2

Query: 56  MAVQAPCIQLNDGNTIPIVAL-GTGRGTAKESDS----IDEVRQAVYWAIEA-GYRHIDT 217
           M++      LN+GN IP +++ GTG    K   S     DE+ + + +A+   G  HID 
Sbjct: 1   MSLTQKFFDLNNGNQIPSISIIGTGTRWFKRPGSEHTFSDELVEQIKYALSLPGIIHIDA 60

Query: 218 AAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYI 397
           A  Y    +    +A+A+      R E+F+T K        +  +  L   LK LGLDY+
Sbjct: 61  AECYGTYPE----LAKALKESSKPRSEIFITDKYSTQTKFTNDPIEGLNTGLKTLGLDYV 116

Query: 398 DLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 577
           DLYLIH P      +   ++   + W+ M+   + G A+SIGVSNF+   I  ++  + I
Sbjct: 117 DLYLIHSPFF--DPEFKGSLTLEKVWKDMETLYKEGKAKSIGVSNFSVKNIEEILKIAGI 174

Query: 578 RPGXNQIE 601
           +P  NQIE
Sbjct: 175 KPQVNQIE 182


>UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4;
           Pichia guilliermondii|Rep: Putative uncharacterized
           protein - Pichia guilliermondii (Yeast) (Candida
           guilliermondii)
          Length = 287

 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 64/180 (35%), Positives = 93/180 (51%), Gaps = 4/180 (2%)
 Frame = +2

Query: 74  CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
           C  L +G+ IP   +G     A ++  I E       A++ GYR IDTA  Y++E + G+
Sbjct: 9   CFPLLNGSRIPACGVGVYLLPASQTAGIVEK------ALDVGYRLIDTAQEYENERETGE 62

Query: 254 GIAEAIANGLVT-REELFVTTKLWNDKHARDQVVPALQESLKKLG-LDYIDLYLIHFPIA 427
           GI   +       RE++  TTK+ N     D+   +L+ESL K+  L+YIDL LIH P++
Sbjct: 63  GIKAWLGKDKNNKREDVLYTTKITNLNQGYDRTWRSLKESLNKVKHLEYIDLVLIHDPLS 122

Query: 428 TKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV--SNSYIRPGXNQIE 601
            K          +ETW+ +Q+A   G+ +SIGVSNF    I  L        +P  NQIE
Sbjct: 123 DKKTR-------IETWKALQEAVDSGMVKSIGVSNFGKHHIQELYDWEGLKYKPIVNQIE 175


>UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 301

 Score = 90.6 bits (215), Expect = 2e-17
 Identities = 57/179 (31%), Positives = 95/179 (53%), Gaps = 5/179 (2%)
 Frame = +2

Query: 80  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259
           + +DG  +P + LG  R   +    +D   +A   A+++GYR  DTA +Y++E  +G  +
Sbjct: 13  KFSDGYEMPKIGLGISR--IETQQDLDVSIEA---ALKSGYRQFDTANLYKNETFLGNSL 67

Query: 260 AEAIANGLVTREELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFP---IA 427
            + +    +TRE++F+TTK+   +++  ++    L  SL  L  DY+DL LIH+P     
Sbjct: 68  KKYLPQFGLTREDVFITTKVRTLNENTVEETEKQLANSLATLQTDYVDLLLIHYPRDRDT 127

Query: 428 TKPDDSPDNIDYLE-TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
              DD   N    +  WQ ++ A++ G  RSIGVSN+    +  +   + IRP  NQ E
Sbjct: 128 GNDDDYEINKSRRKIVWQTLEKAKESGRVRSIGVSNYEVYHLVEMFEYAKIRPVLNQYE 186


>UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 287

 Score = 90.6 bits (215), Expect = 2e-17
 Identities = 56/178 (31%), Positives = 94/178 (52%), Gaps = 4/178 (2%)
 Frame = +2

Query: 80  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259
           +L +G  IP +ALGT           D++  AV  A++ GYR  DTA  Y++E+ +G  +
Sbjct: 3   KLKNGQEIPKLALGTYEAKG------DQLFAAVDEALKVGYRSFDTAKYYENEKDLGLAL 56

Query: 260 AEAIANGLVTREELFVTTKL--WNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
              +    +  E++++T+K+  ++ K+A + +   + ESL+ L   Y+DL L+H+P    
Sbjct: 57  KTLLPRHNICSEDIYLTSKVFPYSSKNAAELIRKDVNESLELLDRKYLDLVLVHYPRPLD 116

Query: 434 PDDSPDN--IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
            +D  +N  +   +TW  ++     G  RSIGVSN+    I  + S   I P  NQIE
Sbjct: 117 TEDLNENNKMYRKDTWIALEKLHAEGKIRSIGVSNYEPHHIEEMRSYITIEPQVNQIE 174


>UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1;
           Actinomyces odontolyticus ATCC 17982|Rep: Putative
           uncharacterized protein - Actinomyces odontolyticus ATCC
           17982
          Length = 282

 Score = 89.8 bits (213), Expect = 4e-17
 Identities = 62/175 (35%), Positives = 95/175 (54%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           I LN+G TIP V LGT      E D   + + AV +A++  Y  IDTA VY +E  VG+G
Sbjct: 4   ITLNNGITIPQVGLGT---YLLEPD---DAQSAVTYALDNDYTLIDTANVYVNERAVGRG 57

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
           +  +       R+E+F+ TKLW     R     A++E+L++LG DYIDL ++H P     
Sbjct: 58  MRASSK----ARDEIFLETKLWPSFFER---ASAVEETLERLGTDYIDLMILHQPAG--- 107

Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                  D +  ++ ++ A + G  R+IG+SNF+  Q  R++    + P  NQ+E
Sbjct: 108 -------DTVAGYRILEKAHKEGKIRAIGLSNFDVAQTQRILDECEVVPTINQVE 155


>UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1;
           Vitis vinifera|Rep: Putative uncharacterized protein -
           Vitis vinifera (Grape)
          Length = 212

 Score = 89.4 bits (212), Expect = 6e-17
 Identities = 60/177 (33%), Positives = 94/177 (53%), Gaps = 9/177 (5%)
 Frame = +2

Query: 92  GNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI 271
           G  IP+V + T       S+++ +   ++  AIE GYRH D  A Y  E+ +G+ I +A+
Sbjct: 7   GKAIPLVGMVTTVYPFAPSETMID---SILTAIELGYRHFDCVAAYLSEKPLGEAIKKAV 63

Query: 272 ANGLV-TREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD--D 442
             GL+ +R+ELF+T +  N                  L LDY+DLYLIH+ ++ KP   +
Sbjct: 64  KLGLIKSRDELFITLQALN------------------LQLDYLDLYLIHWSVSLKPGNYE 105

Query: 443 SPDN------IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQ 595
            P N      ID    W+ M+D ++L L ++IGVSNF+  ++  L+  + I P  NQ
Sbjct: 106 LPVNKDDHLPIDLGSVWKAMEDFQKLSLTKAIGVSNFSCNKLEELLQTASILPAVNQ 162


>UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto
           reductase family - Thermotoga maritima
          Length = 274

 Score = 89.0 bits (211), Expect = 8e-17
 Identities = 61/166 (36%), Positives = 90/166 (54%), Gaps = 6/166 (3%)
 Frame = +2

Query: 92  GNTIPIVALGT-GRGTAKESDSI--DEVRQAVYWAIEAGYRHIDTAAVY---QDEEQVGQ 253
           G  IP + LGT G G  +  D    +E+ + +  AI+ GY HIDTA  Y     EE +G+
Sbjct: 10  GEEIPALGLGTWGIGGFETPDYSRDEEMVELLKTAIKMGYTHIDTAEYYGGGHTEELIGK 69

Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
            I +        RE+LF+ +K+W     RD ++ +L+ +LK+L  DY+DLYLIH+P    
Sbjct: 70  AIKD------FRREDLFIVSKVWPTHLRRDDLLRSLENTLKRLDTDYVDLYLIHWP---- 119

Query: 434 PDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 571
              +P+ I   ET   M +  + GL R IGVSNF+   +   +S S
Sbjct: 120 ---NPE-IPLEETLSAMAEGVRQGLIRYIGVSNFDRRLLEEAISKS 161


>UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=5; Lactobacillus|Rep: Aldo/keto
           reductase of diketogulonate reductase family -
           Lactobacillus brevis (strain ATCC 367 / JCM 1170)
          Length = 282

 Score = 89.0 bits (211), Expect = 8e-17
 Identities = 58/174 (33%), Positives = 94/174 (54%)
 Frame = +2

Query: 80  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259
           +L DG  +P++    G GT   +D    +  A+  A +AGYR  DTA +Y++E+ +G  I
Sbjct: 11  KLADGRQMPVM----GFGTYLLNDQ-PTMNTAIQTAWDAGYRMFDTAMLYRNEDILGPAI 65

Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 439
            +    GL  RE LF+T+K+       DQ + A++ SLK+L  DY+DL LIH+P+     
Sbjct: 66  QQL---GL-PREGLFLTSKVAEIVQGYDQTMKAVEGSLKRLQTDYLDLLLIHWPVRE--- 118

Query: 440 DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                  + +TW+ ++  +  G  +SIGVSN+    +  L + +   P  NQ+E
Sbjct: 119 ------HFFDTWRALEQLKADGQVKSIGVSNYTIAHLELLATKAKEMPVVNQVE 166


>UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1;
           Coccidioides immitis|Rep: Putative uncharacterized
           protein - Coccidioides immitis
          Length = 324

 Score = 89.0 bits (211), Expect = 8e-17
 Identities = 63/170 (37%), Positives = 89/170 (52%), Gaps = 11/170 (6%)
 Frame = +2

Query: 125 GRGTAKESDSI---DEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTRE 295
           G GT +   S+     V+ +V  A++ GYRHID A  Y     V +GI  AI    V RE
Sbjct: 20  GLGTFQVDPSLYPEGSVKDSVLHALKIGYRHIDAALAY-GWGSVERGIGAAIRASGVPRE 78

Query: 296 ELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLI---HFPIATKPDDSP-DNID- 460
           ++FV TKL N  HA + V   +  SLK LGL Y+        ++    KPD  P  +I+ 
Sbjct: 79  DVFVVTKLHNCFHAPEDVEVGMNMSLKNLGLGYVPYAYTKGENYSTVRKPDGKPVVDIEL 138

Query: 461 ---YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
              +  TW+ M++    G A+ IGVSNF+  ++ RL+S   I P  NQ+E
Sbjct: 139 SRAFDTTWKAMENLVDQGKAKLIGVSNFSTPKLKRLLSVCRIFPVVNQVE 188


>UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 293

 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 58/150 (38%), Positives = 82/150 (54%), Gaps = 3/150 (2%)
 Frame = +2

Query: 161 EVRQAVYWAIE-AGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLW-NDKH 334
           E +QA+  A + AGYRH+DTA  Y++E   G+ + E      V R ELF TTK++ N+  
Sbjct: 41  ECKQALLNAFDKAGYRHVDTARYYRNEADCGEAVRECS----VPRSELFYTTKVYLNEMG 96

Query: 335 ARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLAR 514
              +   A+++SL K GLDY+DL L+H P   K          L++W  + +  Q G  R
Sbjct: 97  GGSKTRLAVEDSLAKAGLDYLDLVLLHAPDGGKK-------FRLDSWDTLTELVQEGKVR 149

Query: 515 SIGVSNFNATQITRLV-SNSYIRPGXNQIE 601
           S+GVSNF    I  L+ S   + P  NQIE
Sbjct: 150 SLGVSNFGPHHIQELIDSKPKVLPVCNQIE 179


>UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6;
           Halobacteriaceae|Rep: Aldehyde reductase - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 279

 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 52/137 (37%), Positives = 77/137 (56%)
 Frame = +2

Query: 125 GRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 304
           G GT +  D+ ++  ++V  A+EAGYRHIDTA  Y +E  VG GIA A     V R+++F
Sbjct: 21  GLGTWQNEDA-EQCAESVRTALEAGYRHIDTAQAYDNESAVGDGIAAAD----VDRDDIF 75

Query: 305 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 484
           + TK+W    + D V+   +ESL KLG+D +DL  +H+      +  P+     ET    
Sbjct: 76  LATKVWISNLSHDDVIETTEESLDKLGVDSVDLLYVHWAAG---EYEPE-----ETLPAF 127

Query: 485 QDARQLGLARSIGVSNF 535
            +    GL  ++GVSNF
Sbjct: 128 DELVDRGLIDNVGVSNF 144


>UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2;
           Caenorhabditis|Rep: Probable oxidoreductase ZK1290.5 -
           Caenorhabditis elegans
          Length = 321

 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 62/178 (34%), Positives = 94/178 (52%), Gaps = 1/178 (0%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P   L++   +P++ LGT        D++      ++   + GYR IDTA  Y  E+Q+G
Sbjct: 3   PTTVLSNNVEMPLIGLGTTHSGGYYHDAV------LHSIKKCGYRLIDTAKRYGVEKQLG 56

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430
                A+ N  V REE+F++TKLW      D+V  A Q S +KL  DY+D+Y+IH P   
Sbjct: 57  I----AVKNCSVPREEMFLSTKLW-PVDCGDEVYNAFQTSCEKLQTDYLDMYMIHMP--Q 109

Query: 431 KPDDSPDNIDYLE-TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
            PD   +  +  E TW+ M+   +    RSIGVSN++   +  L+  + I P  NQ+E
Sbjct: 110 LPDWIVNQKETKEKTWRQMELLYEDEHVRSIGVSNYSIEDLDELLEFASILPHANQVE 167


>UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1;
           Filobasidiella neoformans|Rep: Oxidoreductase, putative
           - Cryptococcus neoformans (Filobasidiella neoformans)
          Length = 321

 Score = 88.2 bits (209), Expect = 1e-16
 Identities = 71/189 (37%), Positives = 104/189 (55%), Gaps = 15/189 (7%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAA---VYQDEEQV 247
           I LNDG+ IP +A GT +   KE     +V QA    I+ G+ HIDTA    VY +EE+V
Sbjct: 6   ITLNDGHRIPAIAFGTWK-IPKEVTPF-QVGQA----IDVGFDHIDTAQGRIVYHNEEEV 59

Query: 248 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427
           GQ I E+   GL +R +L+VTTK W+    +     ++ ESL+KLGL+Y+DLYLIH P  
Sbjct: 60  GQAIKES---GL-SRNQLWVTTK-WSGIDGKG-ARQSIGESLEKLGLEYLDLYLIHSPQV 113

Query: 428 TKPDDSPDNIDYLETWQGMQDARQLGLARSIGVS------------NFNATQITRLVSNS 571
           TK  D       LET Q     + +G+++ +               +FN  Q+  L++++
Sbjct: 114 TK-GDIKGAWKELETLQKEGKTKSIGVSKQVYYQTIFFASLSDVWDSFNKEQLQELLAHA 172

Query: 572 YIRPGXNQI 598
            ++P  NQI
Sbjct: 173 TVKPVVNQI 181


>UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1;
           Schizosaccharomyces pombe|Rep: Xylose and arabinose
           reductase - Schizosaccharomyces pombe (Fission yeast)
          Length = 275

 Score = 88.2 bits (209), Expect = 1e-16
 Identities = 52/144 (36%), Positives = 80/144 (55%), Gaps = 1/144 (0%)
 Frame = +2

Query: 173 AVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVV 352
           +VY A++ GYRHID+A +Y +E   G+ I + +      RE+++ T+KL ND       +
Sbjct: 32  SVYAALQCGYRHIDSAQMYHNEADCGRAILKFMEETGTKREDIWFTSKL-NDLSGYKSTL 90

Query: 353 PALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSN 532
            ++  S+K  GL YIDL+L+H P            D +E+W+ ++   + G  R+IGVSN
Sbjct: 91  SSIDASVKACGLGYIDLFLLHSPYG----------DRIESWKALEKGVEEGKLRAIGVSN 140

Query: 533 FNATQITRLV-SNSYIRPGXNQIE 601
           F    I  L+ S+  I P  NQIE
Sbjct: 141 FGPHHIQELLDSHPKIIPCVNQIE 164


>UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma
           penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
          Length = 289

 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 65/175 (37%), Positives = 91/175 (52%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           I LN+GN IP +  G  +   KE     E    V  AI  GYR IDTA  Y +E++ G G
Sbjct: 9   ITLNNGNKIPSIGFGVFQ-IPKE-----ETADCVKKAISIGYRLIDTAQAYHNEKETGLG 62

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
           I     +G V REE+F+TTK+W   + R     ++ ESLK+L   Y+DL L+H P     
Sbjct: 63  IK---LSG-VKREEIFLTTKVWVSNYER--CYESVIESLKRLDTSYLDLILLHQPFG--- 113

Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                  +Y + +Q ++   +    R+IGVSNF   +I  L   + I+P  NQIE
Sbjct: 114 -------NYYKAYQDLERLYKENKVRNIGVSNFWDNRIIDLCFFNQIKPMVNQIE 161


>UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina
           baltica OS145|Rep: Aldo/keto reductase - Idiomarina
           baltica OS145
          Length = 263

 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 54/136 (39%), Positives = 77/136 (56%)
 Frame = +2

Query: 161 EVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR 340
           E+   V  AI+ GY HIDTA  Y +E  VG+ +A+       T +++FVTTK+W +K A 
Sbjct: 16  ELTDLVSAAIDMGYEHIDTAQFYGNEADVGKALAQH------TNKDVFVTTKVWYEKLAY 69

Query: 341 DQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSI 520
             V+ +LQ S  KL  D IDL LIH+P    P+   D +   ET   +Q A+Q GL + +
Sbjct: 70  QDVLDSLQVSRDKLQRDTIDLALIHWP---SPN---DEVPVEETLDALQKAQQDGLIKHL 123

Query: 521 GVSNFNATQITRLVSN 568
           GVSNF    + R  ++
Sbjct: 124 GVSNFTIDLLNRAAAH 139


>UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=3; Lactococcus lactis|Rep: Oxidoreductase,
           aldo/keto reductase family - Lactococcus lactis subsp.
           cremoris (strain MG1363)
          Length = 281

 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 59/175 (33%), Positives = 91/175 (52%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           I LNDGN IP   LG  +    E+        AV  A+  GYRHIDTA  YQ+E  VG+ 
Sbjct: 5   IVLNDGNIIPQFGLGVYQIPEGEA-----TENAVKEALRLGYRHIDTAHAYQNERSVGR- 58

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
              AI +  +   E+++T+KLW   +  D    A++  L+ L L  IDL L+H  +    
Sbjct: 59  ---AIHSSGIPISEIWITSKLWPSDY--DDASQAIERMLELLNLKQIDLLLLHQQVG--- 110

Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
                  +Y + W  +++A + G  +SIG+SNF+  ++  L + + I+P   Q+E
Sbjct: 111 -------NYRKAWIALENAVKSGKVKSIGISNFDGERLVDLFNFADIKPSALQVE 158


>UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1;
           Sulfitobacter sp. NAS-14.1|Rep: Putative uncharacterized
           protein - Sulfitobacter sp. NAS-14.1
          Length = 274

 Score = 87.4 bits (207), Expect = 2e-16
 Identities = 55/148 (37%), Positives = 75/148 (50%)
 Frame = +2

Query: 158 DEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHA 337
           D V   V  A+  G+RHIDTA  YQ+EEQVG+G+  A     V R+E+F+TTK+  +  +
Sbjct: 24  DTVADMVAAALSEGFRHIDTAQAYQNEEQVGEGLRRAD----VRRDEVFLTTKILPEHFS 79

Query: 338 RDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARS 517
            +    A   SLK+LG DY+DL L+H+P    P          ET   + D    G  R 
Sbjct: 80  PEAFTAAADASLKRLGTDYVDLLLLHWPSKEVP--------IAETIGALNDLISAGKVRH 131

Query: 518 IGVSNFNATQITRLVSNSYIRPGXNQIE 601
            GVSNF    + +  +        NQIE
Sbjct: 132 GGVSNFTMDMVDQAQAALNTPLAANQIE 159


>UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1;
           Actinobacillus succinogenes 130Z|Rep: Aldo/keto
           reductase precursor - Actinobacillus succinogenes 130Z
          Length = 315

 Score = 87.0 bits (206), Expect = 3e-16
 Identities = 56/175 (32%), Positives = 98/175 (56%)
 Frame = +2

Query: 77  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
           ++LN+G  +PI+ +G    T ++++      ++V  A++AGYR IDTA +Y++E+ VG+ 
Sbjct: 45  VKLNNGIEMPIIGIGVWTLTPEQTE------KSVGEALKAGYRLIDTARMYRNEQAVGR- 97

Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
              A+ +  + REE+F+TTK++      +    A+ E L+ L  DYIDL L+H+P     
Sbjct: 98  ---AVRDSGIPREEIFITTKIYGSGDYAN-AEAAINERLRLLDTDYIDLLLLHYP----- 148

Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601
            D  D     + W+ M+   + G  R+IG+SN++     R++  + I P   Q E
Sbjct: 149 -DQNDT----KAWKVMEQFVKAGKIRAIGLSNYHRKTFNRIMQAATITPAVVQNE 198


>UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;
           n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
           hypothetical protein - Ornithorhynchus anatinus
          Length = 419

 Score = 85.8 bits (203), Expect = 7e-16
 Identities = 53/140 (37%), Positives = 76/140 (54%)
 Frame = +2

Query: 71  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250
           P + L +G  IPI+ LGT        D++      +Y   E G RHIDTA  Y  E  +G
Sbjct: 13  PTVPLANGLNIPILGLGTSHVGGYSHDAV------IYALKECGIRHIDTAKRYGCELLLG 66

Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430
           + I E+   G V REEL++TTKLW   +  +    +  ES  +LG++Y+DL+LIH+P A 
Sbjct: 67  KAIQES---G-VKREELWITTKLWLTDYGYESAKQSCLESCNRLGVEYLDLFLIHWPDAQ 122

Query: 431 KPDDSPDNIDYLETWQGMQD 490
            P  S       ETW+ M++
Sbjct: 123 LPGKSSREA-RAETWRAMEE 141


>UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2;
           Oceanicola granulosus HTCC2516|Rep:
           2,5-didehydrogluconate reductase - Oceanicola granulosus
           HTCC2516
          Length = 275

 Score = 85.8 bits (203), Expect = 7e-16
 Identities = 59/150 (39%), Positives = 79/150 (52%)
 Frame = +2

Query: 104 PIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGL 283
           P +  G G GT       D +  A+  A+E GYRH+DTA  Y  E +VG+ I  A   GL
Sbjct: 9   PEIMPGLGFGTYGRQGE-DGI-SAILCALETGYRHLDTAQDYDTEAEVGEAIRRA---GL 63

Query: 284 VTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDY 463
             RE LFVTTK+         +VP++  SL+ +GLD  DL LIH+P    P+      DY
Sbjct: 64  -PREALFVTTKVRPANFGPGDLVPSVARSLETMGLDRADLVLIHWP---APNGERPLSDY 119

Query: 464 LETWQGMQDARQLGLARSIGVSNFNATQIT 553
           +     + +AR  GL R +GVSNF    +T
Sbjct: 120 IPQ---LAEARAQGLTRHVGVSNFPVALLT 146


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 617,181,928
Number of Sequences: 1657284
Number of extensions: 12255494
Number of successful extensions: 38549
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 36461
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 37770
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 43147568152
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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