BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= epV31104 (606 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 230 2e-59 UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 180 2e-44 UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 179 4e-44 UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 171 1e-41 UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 162 7e-39 UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 155 6e-37 UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 155 1e-36 UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 153 4e-36 UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 153 4e-36 UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 151 9e-36 UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 151 9e-36 UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 151 1e-35 UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 151 2e-35 UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 150 2e-35 UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 146 3e-34 UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 146 5e-34 UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 146 5e-34 UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 145 6e-34 UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 145 8e-34 UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 144 1e-33 UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 143 3e-33 UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 143 3e-33 UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 143 3e-33 UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 142 4e-33 UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 142 6e-33 UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 142 6e-33 UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 141 1e-32 UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 141 1e-32 UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 140 2e-32 UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 140 2e-32 UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 139 5e-32 UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 139 5e-32 UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 138 7e-32 UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 138 7e-32 UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 138 9e-32 UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 138 9e-32 UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 138 1e-31 UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 137 2e-31 UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 136 3e-31 UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 136 3e-31 UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 136 5e-31 UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 136 5e-31 UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 136 5e-31 UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 135 9e-31 UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 134 1e-30 UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 134 2e-30 UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 134 2e-30 UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 133 3e-30 UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 133 4e-30 UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 133 4e-30 UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 132 5e-30 UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 132 5e-30 UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 132 6e-30 UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 132 8e-30 UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 131 1e-29 UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 131 1e-29 UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 130 2e-29 UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 130 2e-29 UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 130 2e-29 UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 130 3e-29 UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 129 4e-29 UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 129 6e-29 UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 129 6e-29 UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 128 1e-28 UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 128 1e-28 UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 128 1e-28 UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 127 2e-28 UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 127 2e-28 UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 127 2e-28 UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 127 2e-28 UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 127 2e-28 UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 127 2e-28 UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 127 2e-28 UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 127 2e-28 UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 126 3e-28 UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 126 4e-28 UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 126 5e-28 UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 125 7e-28 UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 125 9e-28 UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 125 9e-28 UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 124 1e-27 UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 124 1e-27 UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 124 1e-27 UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 124 2e-27 UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 124 2e-27 UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 124 2e-27 UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 124 2e-27 UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 123 3e-27 UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 123 4e-27 UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 122 7e-27 UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 122 7e-27 UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 122 7e-27 UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 121 1e-26 UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 121 1e-26 UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 121 1e-26 UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 120 3e-26 UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 120 4e-26 UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 119 5e-26 UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 119 5e-26 UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 119 5e-26 UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 119 5e-26 UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 119 6e-26 UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 119 6e-26 UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 119 6e-26 UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 118 8e-26 UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 118 8e-26 UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 118 1e-25 UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 118 1e-25 UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 118 1e-25 UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 118 1e-25 UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 118 1e-25 UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 117 2e-25 UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 117 2e-25 UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 117 2e-25 UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 117 2e-25 UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 117 2e-25 UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 117 2e-25 UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 116 3e-25 UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 116 4e-25 UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 116 4e-25 UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 116 6e-25 UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 115 8e-25 UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 115 8e-25 UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 115 1e-24 UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 115 1e-24 UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 115 1e-24 UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 114 1e-24 UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 114 2e-24 UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 114 2e-24 UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 114 2e-24 UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 114 2e-24 UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 114 2e-24 UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 113 3e-24 UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 113 4e-24 UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 113 4e-24 UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 113 4e-24 UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 112 5e-24 UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 112 5e-24 UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 112 5e-24 UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 112 5e-24 UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 112 7e-24 UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 112 7e-24 UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 111 1e-23 UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 111 1e-23 UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 111 1e-23 UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 111 1e-23 UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 111 1e-23 UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 111 2e-23 UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 111 2e-23 UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 111 2e-23 UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 102 2e-23 UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 110 2e-23 UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 110 2e-23 UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 110 3e-23 UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 110 3e-23 UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 110 3e-23 UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 109 4e-23 UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 109 4e-23 UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 109 7e-23 UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 109 7e-23 UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 109 7e-23 UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 109 7e-23 UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 109 7e-23 UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 108 9e-23 UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 108 1e-22 UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 107 3e-22 UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 107 3e-22 UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 107 3e-22 UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 107 3e-22 UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 106 5e-22 UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 106 5e-22 UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 106 5e-22 UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 106 5e-22 UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 106 5e-22 UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 106 5e-22 UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 105 6e-22 UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 105 6e-22 UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 105 8e-22 UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 105 8e-22 UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 104 1e-21 UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 104 1e-21 UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 104 2e-21 UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 103 3e-21 UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 103 3e-21 UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 103 4e-21 UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 103 4e-21 UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 103 4e-21 UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 103 4e-21 UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 102 6e-21 UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 102 8e-21 UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 102 8e-21 UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 101 1e-20 UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 101 1e-20 UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 101 2e-20 UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 100 2e-20 UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 100 3e-20 UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 100 3e-20 UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 99 4e-20 UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 86 4e-20 UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 100 5e-20 UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 100 5e-20 UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 99 7e-20 UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 99 9e-20 UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 99 9e-20 UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 98 1e-19 UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 98 2e-19 UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 97 2e-19 UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 97 3e-19 UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 97 3e-19 UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 97 3e-19 UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 97 4e-19 UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 97 4e-19 UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 96 5e-19 UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 96 7e-19 UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 96 7e-19 UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 96 7e-19 UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 95 1e-18 UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 95 2e-18 UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 95 2e-18 UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 94 2e-18 UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 94 3e-18 UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 94 3e-18 UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 93 4e-18 UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 93 4e-18 UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 93 4e-18 UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 93 4e-18 UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 93 4e-18 UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 92 8e-18 UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 91 2e-17 UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 91 2e-17 UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 91 2e-17 UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 91 2e-17 UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 91 2e-17 UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 90 4e-17 UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 89 6e-17 UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 89 8e-17 UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 89 8e-17 UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 89 8e-17 UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 89 1e-16 UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 89 1e-16 UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 89 1e-16 UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 88 1e-16 UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 88 1e-16 UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 88 2e-16 UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 88 2e-16 UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 88 2e-16 UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 87 2e-16 UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 87 3e-16 UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;... 86 7e-16 UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 86 7e-16 UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 86 7e-16 UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 86 7e-16 UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 85 9e-16 UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 85 1e-15 UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 85 2e-15 UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 84 2e-15 UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 84 3e-15 UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 84 3e-15 UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 83 4e-15 UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 83 5e-15 UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 82 9e-15 UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 82 9e-15 UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 82 1e-14 UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 82 1e-14 UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 81 2e-14 UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 81 2e-14 UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 81 2e-14 UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 81 3e-14 UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 79 6e-14 UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 79 6e-14 UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 79 6e-14 UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 79 8e-14 UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 79 1e-13 UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 79 1e-13 UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 78 1e-13 UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 78 2e-13 UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 78 2e-13 UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 77 2e-13 UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 77 2e-13 UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei... 77 3e-13 UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 77 3e-13 UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 77 3e-13 UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 76 8e-13 UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 75 1e-12 UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 75 1e-12 UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 75 2e-12 UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 63 2e-12 UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 74 3e-12 UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc... 74 3e-12 UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 73 4e-12 UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 73 4e-12 UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 73 4e-12 UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 73 5e-12 UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto... 73 7e-12 UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere... 71 2e-11 UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 71 3e-11 UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ... 70 4e-11 UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 70 4e-11 UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 69 7e-11 UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 69 1e-10 UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 68 2e-10 UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 68 2e-10 UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 68 2e-10 UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 67 3e-10 UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 66 5e-10 UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 66 5e-10 UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 66 6e-10 UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 66 6e-10 UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ... 66 8e-10 UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ... 65 1e-09 UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 65 1e-09 UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom... 64 2e-09 UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 64 2e-09 UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta... 64 2e-09 UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ... 64 2e-09 UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 64 2e-09 UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 64 2e-09 UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 64 2e-09 UniRef50_Q9C2J8 Cluster: Related to D-xylose reductase II, III p... 64 3e-09 UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter... 63 4e-09 UniRef50_P80874 Cluster: General stress protein 69; n=16; cellul... 63 6e-09 UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 62 7e-09 UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 62 1e-08 UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 62 1e-08 UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 62 1e-08 UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria... 61 2e-08 UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3.... 61 2e-08 UniRef50_Q67NQ1 Cluster: Oxidoreductase; n=1; Symbiobacterium th... 60 3e-08 UniRef50_Q88TP1 Cluster: Oxidoreductase; n=3; Bacteria|Rep: Oxid... 60 4e-08 UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga... 59 7e-08 UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 59 7e-08 UniRef50_A6X3I0 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 59 9e-08 UniRef50_A4RPC9 Cluster: Putative uncharacterized protein; n=1; ... 59 9e-08 UniRef50_Q5KPU6 Cluster: Putative uncharacterized protein; n=2; ... 58 1e-07 UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 58 2e-07 UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:... 58 2e-07 UniRef50_A6WAE5 Cluster: Aldo/keto reductase; n=1; Kineococcus r... 58 2e-07 UniRef50_A5VEK4 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 58 2e-07 UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 58 2e-07 UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact... 58 2e-07 UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ... 58 2e-07 UniRef50_A1CHK2 Cluster: Aldose 1-epimerase, putative; n=11; Pez... 58 2e-07 UniRef50_Q3I1P2 Cluster: Aldo-keto oxidoreductase; n=6; Bacteria... 57 4e-07 UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 57 4e-07 UniRef50_P0A9T5 Cluster: Protein tas; n=88; Bacteria|Rep: Protei... 57 4e-07 UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 56 5e-07 UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia... 56 5e-07 UniRef50_A7AFQ7 Cluster: Putative uncharacterized protein; n=1; ... 56 5e-07 UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap... 56 5e-07 UniRef50_Q8TTK4 Cluster: Aldo/keto reductase; n=28; cellular org... 56 9e-07 UniRef50_Q89JX0 Cluster: Oxidoreductase; n=26; Bacteria|Rep: Oxi... 55 1e-06 UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 55 1e-06 UniRef50_Q0TYC7 Cluster: Predicted protein; n=1; Phaeosphaeria n... 55 2e-06 UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 54 2e-06 UniRef50_Q60BI7 Cluster: Oxidoreductase, aldo/keto reductase fam... 54 2e-06 UniRef50_Q08NK7 Cluster: Aldo/keto reductase; n=1; Stigmatella a... 54 2e-06 UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ... 54 2e-06 UniRef50_P77735 Cluster: Uncharacterized oxidoreductase yajO; n=... 54 2e-06 UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 54 3e-06 UniRef50_Q88SS2 Cluster: Oxidoreductase; n=13; Firmicutes|Rep: O... 54 3e-06 UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 54 3e-06 UniRef50_Q034L5 Cluster: Aryl-alcohol dehydrogenase related enzy... 54 3e-06 UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ... 54 3e-06 UniRef50_UPI0001556575 Cluster: PREDICTED: similar to Aldo-keto ... 54 3e-06 UniRef50_Q3WEJ4 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 54 3e-06 UniRef50_Q0RGM0 Cluster: Putative aldoketoreductase; n=2; Franki... 53 5e-06 UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep... 53 5e-06 UniRef50_A0GDL6 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 53 5e-06 UniRef50_UPI000023DAA9 Cluster: hypothetical protein FG00321.1; ... 52 8e-06 UniRef50_Q7NCE7 Cluster: Glr3032 protein; n=5; Cyanobacteria|Rep... 52 1e-05 UniRef50_Q1FGT0 Cluster: Aldo/keto reductase; n=1; Clostridium p... 52 1e-05 UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;... 52 1e-05 UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno... 52 1e-05 UniRef50_A1SJZ0 Cluster: Aldo/keto reductase; n=11; Actinomyceta... 52 1e-05 UniRef50_A0K203 Cluster: Aldo/keto reductase; n=2; Arthrobacter|... 52 1e-05 UniRef50_Q97UG6 Cluster: Oxidoreductase; n=5; Archaea|Rep: Oxido... 52 1e-05 UniRef50_Q983C8 Cluster: Oxido-reductase, and dehydratase; MocA;... 51 2e-05 UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular... 51 2e-05 UniRef50_Q2FGN2 Cluster: Oxidoreductase, aldo/keto reductase fam... 51 2e-05 UniRef50_Q0LKQ4 Cluster: Aldo/keto reductase; n=1; Herpetosiphon... 51 2e-05 UniRef50_A6LWU9 Cluster: Aldo/keto reductase; n=3; Clostridium|R... 51 2e-05 UniRef50_P49261 Cluster: Rho beta-crystallin; n=1; Lepidodactylu... 51 2e-05 UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|... 51 2e-05 UniRef50_Q2J7H2 Cluster: Aldo/keto reductase; n=16; Bacteria|Rep... 51 2e-05 UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy... 51 2e-05 UniRef50_Q1EZH4 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 51 2e-05 UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 51 2e-05 UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|... 51 2e-05 UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 50 3e-05 UniRef50_Q1GSJ8 Cluster: Aldo/keto reductase; n=3; Sphingomonada... 50 3e-05 UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=... 50 3e-05 UniRef50_A7HL79 Cluster: Aldo/keto reductase; n=1; Fervidobacter... 50 4e-05 UniRef50_A5FAZ9 Cluster: Aldo/keto reductase; n=1; Flavobacteriu... 50 4e-05 UniRef50_A3I0G0 Cluster: Oxidoreductase; n=1; Algoriphagus sp. P... 50 4e-05 UniRef50_A0JVH3 Cluster: Aldo/keto reductase; n=17; Bacteria|Rep... 50 4e-05 UniRef50_A7RXR1 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 50 4e-05 UniRef50_P54569 Cluster: Uncharacterized oxidoreductase yqkF; n=... 50 4e-05 UniRef50_Q8YAN3 Cluster: Lmo0084 protein; n=11; Listeria monocyt... 50 6e-05 UniRef50_Q7NJD8 Cluster: Gll1894 protein; n=5; Bacteria|Rep: Gll... 50 6e-05 UniRef50_Q74DE6 Cluster: Oxidoreductase, aldo/keto reductase fam... 50 6e-05 UniRef50_A6CMV7 Cluster: Putative uncharacterized protein; n=2; ... 50 6e-05 UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ... 50 6e-05 UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep... 49 7e-05 UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase... 49 7e-05 UniRef50_Q7UL88 Cluster: DTDP-4-keto-L-6-deoxy-hexose 2,3-reduct... 49 7e-05 UniRef50_Q49V75 Cluster: Putative oxidoreductase; n=1; Staphyloc... 49 7e-05 UniRef50_Q1FGT1 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 49 7e-05 UniRef50_A1ZPI5 Cluster: Oxidoreductase; n=1; Microscilla marina... 49 7e-05 UniRef50_Q40648 Cluster: Probable voltage-gated potassium channe... 49 7e-05 UniRef50_UPI00003C85A8 Cluster: hypothetical protein Faci_030001... 49 1e-04 UniRef50_Q81RN9 Cluster: Oxidoreductase, aldo/keto reductase fam... 49 1e-04 UniRef50_Q7D3N9 Cluster: AGR_pAT_274p; n=3; Proteobacteria|Rep: ... 49 1e-04 UniRef50_Q1GHE2 Cluster: Aldo/keto reductase; n=8; Alphaproteoba... 49 1e-04 UniRef50_A0YSM3 Cluster: Probable oxidoreductase; n=1; Lyngbya s... 49 1e-04 UniRef50_Q6NKP1 Cluster: At5g53580; n=18; cellular organisms|Rep... 49 1e-04 UniRef50_A6S357 Cluster: Putative uncharacterized protein; n=2; ... 49 1e-04 UniRef50_Q98EU0 Cluster: Oxidoreductase; MocA; n=27; Bacteria|Re... 48 1e-04 UniRef50_A3IX63 Cluster: Putative oxidoreductase; n=1; Cyanothec... 48 1e-04 UniRef50_Q8ZXA1 Cluster: Aldo-keto reductase family protein; n=3... 48 1e-04 UniRef50_A3H9H5 Cluster: Aldo/keto reductase; n=2; Archaea|Rep: ... 48 1e-04 UniRef50_Q94A68 Cluster: Uncharacterized oxidoreductase At1g0669... 48 1e-04 UniRef50_A3TNI0 Cluster: Oxidoreductase, aldo/keto reductase fam... 48 2e-04 UniRef50_A1RJL6 Cluster: Aldo/keto reductase; n=37; Bacteria|Rep... 48 2e-04 UniRef50_Q2H7Q3 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04 UniRef50_Q39MY8 Cluster: Aldo/keto reductase; n=10; Bacteria|Rep... 48 2e-04 UniRef50_Q6XUT6 Cluster: Oxido-reductase/dehydratase; n=3; Bacte... 48 2e-04 UniRef50_A4QYG8 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04 UniRef50_A4QYA4 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04 UniRef50_Q8YXI8 Cluster: All1225 protein; n=9; Cyanobacteria|Rep... 47 3e-04 UniRef50_Q11BU4 Cluster: Aldo/keto reductase; n=11; Proteobacter... 47 3e-04 UniRef50_Q0FFB1 Cluster: Aldo/keto reductase; n=1; alpha proteob... 47 3e-04 UniRef50_A6C9W8 Cluster: Aldo/keto reductase; n=2; Planctomyceta... 47 3e-04 UniRef50_Q8VV02 Cluster: Putative oxidoreductase; n=1; Streptomy... 47 4e-04 UniRef50_Q0LP88 Cluster: Aldo/keto reductase; n=4; Bacteria|Rep:... 47 4e-04 UniRef50_Q9VGF3 Cluster: CG18547-PA; n=7; Endopterygota|Rep: CG1... 47 4e-04 UniRef50_Q4WE64 Cluster: Aldo-keto reductase (AKR), putative; n=... 47 4e-04 UniRef50_Q46851 Cluster: Uncharacterized protein yghZ; n=126; Ba... 47 4e-04 UniRef50_Q8G7F7 Cluster: Possible oxidoreductase of the aldo/ket... 46 5e-04 UniRef50_Q04TM6 Cluster: Aryl-alcohol dehydrogenase-related oxid... 46 5e-04 UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy... 46 5e-04 UniRef50_A7AFU4 Cluster: Putative uncharacterized protein; n=1; ... 46 5e-04 UniRef50_A1SLH1 Cluster: Aldo/keto reductase; n=27; Bacteria|Rep... 46 5e-04 UniRef50_A0VAL7 Cluster: Aldo/keto reductase; n=2; Proteobacteri... 46 5e-04 UniRef50_Q9X0R5 Cluster: Oxidoreductase, aldo/keto reductase fam... 46 7e-04 UniRef50_Q98IA6 Cluster: Aryl-alcohol dehydrogenase; n=1; Mesorh... 46 7e-04 UniRef50_Q1GJE2 Cluster: Aldo/keto reductase; n=12; Alphaproteob... 46 7e-04 UniRef50_A6DNQ2 Cluster: YqkF; n=1; Lentisphaera araneosa HTCC21... 46 7e-04 UniRef50_A7E982 Cluster: Putative uncharacterized protein; n=1; ... 46 7e-04 UniRef50_UPI0000611A01 Cluster: PREDICTED: similar to MGC80525 p... 46 0.001 UniRef50_A7B5J6 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001 UniRef50_A0K1H5 Cluster: Aldo/keto reductase; n=6; Actinomycetal... 46 0.001 UniRef50_Q27ST7 Cluster: Oxidoreductase; n=2; Eukaryota|Rep: Oxi... 46 0.001 UniRef50_A1CLD1 Cluster: Gamma-cysteine synthetase regulatory su... 46 0.001 UniRef50_Q7NH41 Cluster: Gll2696 protein; n=1; Gloeobacter viola... 45 0.001 UniRef50_Q6A7U3 Cluster: Putative oxidoreductase; n=1; Propionib... 45 0.001 UniRef50_A6VXU3 Cluster: Aldo/keto reductase; n=14; Proteobacter... 45 0.001 UniRef50_A5CYR4 Cluster: Predicted oxidoreductases; n=2; Clostri... 45 0.001 UniRef50_A0JZE6 Cluster: Aldo/keto reductase; n=1; Arthrobacter ... 45 0.001 UniRef50_UPI0000D9C1BD Cluster: PREDICTED: similar to aldo-keto ... 45 0.002 UniRef50_Q9X123 Cluster: Oxidoreductase, putative; n=4; Bacteria... 45 0.002 UniRef50_Q0BAM8 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 45 0.002 UniRef50_A6FYX9 Cluster: Oxidoreductase; n=1; Plesiocystis pacif... 45 0.002 UniRef50_A4XIJ0 Cluster: Aldo/keto reductase; n=1; Caldicellulos... 45 0.002 UniRef50_A0LHW7 Cluster: Aldo/keto reductase precursor; n=1; Syn... 45 0.002 UniRef50_A0RYR0 Cluster: Oxidoreductase; n=2; cellular organisms... 45 0.002 UniRef50_Q38Z15 Cluster: Putative aldo/keto reductase; n=2; Bact... 44 0.002 UniRef50_Q45RB1 Cluster: Possible oxidoreductase; n=3; Actinomyc... 44 0.002 UniRef50_A7HER9 Cluster: Aldo/keto reductase; n=2; Anaeromyxobac... 44 0.002 UniRef50_A6E9U0 Cluster: Oxidoreductase; n=1; Pedobacter sp. BAL... 44 0.002 UniRef50_A6DVW2 Cluster: Oxidoreductase, aldo/keto reductase fam... 44 0.002 UniRef50_A0ZZJ3 Cluster: Oxidoreductase; n=2; Bifidobacterium ad... 44 0.002 UniRef50_A0Y7Y8 Cluster: Aldo/keto reductase; n=1; marine gamma ... 44 0.002 UniRef50_Q39151 Cluster: K+ channel protein; n=29; cellular orga... 44 0.002 UniRef50_Q5ASJ7 Cluster: Putative uncharacterized protein; n=1; ... 44 0.002 UniRef50_Q97UJ7 Cluster: Oxidoreductase; n=4; Archaea|Rep: Oxido... 44 0.002 UniRef50_O43488 Cluster: Aflatoxin B1 aldehyde reductase member ... 44 0.002 UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel... 44 0.003 UniRef50_Q3WFK9 Cluster: Aldo/keto reductase precursor; n=1; Fra... 44 0.003 UniRef50_A0K0K8 Cluster: Aryl-alcohol dehydrogenase (NADP(+)); n... 44 0.003 UniRef50_Q4WE75 Cluster: Aldehyde reductase (GliO), putative; n=... 44 0.003 UniRef50_Q2NFN7 Cluster: Predicted oxidoreductase; n=1; Methanos... 44 0.003 UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular organis... 44 0.004 UniRef50_Q88T82 Cluster: Oxidoreductase; n=18; Bacteria|Rep: Oxi... 44 0.004 UniRef50_Q6MHN8 Cluster: Potassium voltage-gated channel, shaker... 44 0.004 UniRef50_Q2J8X9 Cluster: Aldo/keto reductase; n=3; Frankia|Rep: ... 44 0.004 UniRef50_Q0SJ60 Cluster: Possible aldo/keto reductase; n=50; Bac... 44 0.004 UniRef50_A7GIW7 Cluster: Oxidoreductase, aldo/keto reductase fam... 44 0.004 UniRef50_A6EEC4 Cluster: Putative Norsolorinic acid reductase; n... 44 0.004 UniRef50_A0YC40 Cluster: Putative uncharacterized protein; n=1; ... 44 0.004 UniRef50_A0UVR1 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 44 0.004 UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa... 44 0.004 UniRef50_P76187 Cluster: Oxidoreductase ydhF; n=51; Gammaproteob... 44 0.004 UniRef50_Q4TC86 Cluster: Chromosome undetermined SCAF7044, whole... 43 0.005 UniRef50_Q0LSA5 Cluster: Aldo/keto reductase; n=2; Proteobacteri... 43 0.005 UniRef50_Q01U06 Cluster: Aldo/keto reductase; n=1; Solibacter us... 43 0.005 UniRef50_Q2NGB6 Cluster: Predicted oxidoreductase; n=1; Methanos... 43 0.005 UniRef50_Q0W0V6 Cluster: Predicted aldo/keto reductase; n=2; Eur... 43 0.005 UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose red... 43 0.006 UniRef50_Q9PCQ5 Cluster: Sugar-phosphate dehydrogenase; n=23; Ba... 43 0.006 UniRef50_Q09D95 Cluster: Ydhf chain A; n=1; Stigmatella aurantia... 43 0.006 >UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase - Trichoplusia ni (Cabbage looper) Length = 308 Score = 230 bits (563), Expect = 2e-59 Identities = 119/195 (61%), Positives = 143/195 (73%), Gaps = 3/195 (1%) Frame = +2 Query: 26 ITLTCLLNAAMAV--QAPCIQLNDGNTIPIVALGT-GRGTAKESDSIDEVRQAVYWAIEA 196 + L L+NA +AP QLNDGN IP +ALGT G G I +VRQAV WAI+A Sbjct: 8 VALWALVNAISGEPGKAPLKQLNDGNAIPSLALGTFGFG------DIPKVRQAVLWAIQA 61 Query: 197 GYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLK 376 GYRHIDTAA+Y +EE+VG+GIA+AI GLV REELFVTTKLWNDKH R QVVPAL+ESL Sbjct: 62 GYRHIDTAALYGNEEEVGKGIADAIQQGLVKREELFVTTKLWNDKHGRHQVVPALRESLT 121 Query: 377 KLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITR 556 KLGL Y+DLYLIH P AT + P +ID L TW GM++A++LGLA+SIGVSNF+ + R Sbjct: 122 KLGLSYVDLYLIHSPEATNENGDPVDIDVLNTWNGMEEAKKLGLAKSIGVSNFDTALLDR 181 Query: 557 LVSNSYIRPGXNQIE 601 L++ S P NQIE Sbjct: 182 LIAGSNTVPAVNQIE 196 >UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to GA10458-PA - Nasonia vitripennis Length = 569 Score = 180 bits (439), Expect = 2e-44 Identities = 90/188 (47%), Positives = 127/188 (67%), Gaps = 11/188 (5%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P + NDG +P++ LGT EV +AV +AIE GYRH+DTA Y++E+++G Sbjct: 4 PTVTFNDGYKMPMIGLGTFLSKP------GEVAEAVKYAIEVGYRHVDTAFFYENEKEIG 57 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430 I E I +G + RE++FVTTKLW + H D+VVPA ++SL+ LG DYIDL+L+H+P A Sbjct: 58 SAIREKINDGTIKREDIFVTTKLWCNSHKEDEVVPACKKSLENLGFDYIDLFLVHWPFAF 117 Query: 431 K------PDDSPDNI-----DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 577 K P D+ I DYLETW+GM++ ++ GLARSIG+SNFN+ QI RL+S++ I Sbjct: 118 KSGDALTPRDAAGKIEFSDTDYLETWKGMEECKRQGLARSIGLSNFNSEQIARLLSSAKI 177 Query: 578 RPGXNQIE 601 +P NQ+E Sbjct: 178 KPVNNQVE 185 Score = 148 bits (359), Expect = 9e-35 Identities = 80/165 (48%), Positives = 108/165 (65%), Gaps = 9/165 (5%) Frame = +2 Query: 134 TAKESDSIDEV-RQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 310 T +E +I+++ + Y + YRHIDTA +Y +E+ +G I E I +G V RE+LFVT Sbjct: 278 TPEEVSTIEKMGKHNKYLILLYRYRHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVT 337 Query: 311 TKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA-----TKPDDSP---DNIDYL 466 TKL H +VVPA ++SL LGLDYIDLYLIH+PI K + DYL Sbjct: 338 TKLSYYAHKESEVVPACKQSLNDLGLDYIDLYLIHWPIRRYFRHNKNASGKLLLSDTDYL 397 Query: 467 ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 ETW+GM++ ++ GLARSIGVSNFN+ QITRL+ + I+P NQ+E Sbjct: 398 ETWKGMEECKRQGLARSIGVSNFNSEQITRLLEAAKIKPVNNQVE 442 >UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 321 Score = 179 bits (436), Expect = 4e-44 Identities = 91/186 (48%), Positives = 126/186 (67%), Gaps = 11/186 (5%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 I L+DGN +P++ LGT +G + DEV AV AI+AGYRH D A+ Y +E ++G+ Sbjct: 8 ITLSDGNKVPVLGLGTWQG----GNDPDEVENAVKLAIDAGYRHFDCASFYGNEAEIGKA 63 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP----- 421 I E I G+V RE+LFV TK+WND+ ++ VV A + SLKKLGL YIDLYL+H+P Sbjct: 64 IQEKIDQGVVKREDLFVVTKVWNDERKQELVVAACKRSLKKLGLGYIDLYLVHWPFSYPI 123 Query: 422 ------IATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRP 583 + T + D +DY+ETW+GM++ +LGL RSIGVSNFN+ Q+TRL+ ++ I+P Sbjct: 124 LYQYIVLPTYNAVTLDEVDYIETWRGMEECIKLGLTRSIGVSNFNSQQLTRLLESASIKP 183 Query: 584 GXNQIE 601 NQIE Sbjct: 184 VMNQIE 189 >UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precursor; n=1; Spodoptera littoralis|Rep: 3-dehydroecdysone 3beta-reductase precursor - Spodoptera littoralis (Egyptian cotton leafworm) Length = 345 Score = 171 bits (415), Expect = 1e-41 Identities = 84/196 (42%), Positives = 122/196 (62%), Gaps = 3/196 (1%) Frame = +2 Query: 23 IITLTCLLNAAMAVQAPCIQLNDGNTIPIVALGTGRGTAKES--DSID-EVRQAVYWAIE 193 I+ L C + + P +++ + +P +ALGT G K S D ++R V AI+ Sbjct: 7 ILLLACCGAMSATIDVPMLKMLNDREMPAIALGTYLGFDKGGAVTSKDKQLRNVVMQAID 66 Query: 194 AGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESL 373 GYRH DTAA+Y E +VG+ I I G++ RE++F+TTKLWN H R+QV A++E+L Sbjct: 67 LGYRHFDTAAIYNTEAEVGEAIRMKIDEGVIKREDVFLTTKLWNTHHKREQVAVAMKETL 126 Query: 374 KKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQIT 553 K GLDY+DL+L+H+PIA D S N DYLETW+ ++ +LG +SIG+SNFN Q+ Sbjct: 127 NKTGLDYVDLFLMHWPIALNEDYSHSNTDYLETWRATEEMVKLGYTKSIGLSNFNKLQVA 186 Query: 554 RLVSNSYIRPGXNQIE 601 ++ I+P QIE Sbjct: 187 TVLQECTIKPVALQIE 202 >UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p - Drosophila melanogaster (Fruit fly) Length = 311 Score = 162 bits (393), Expect = 7e-39 Identities = 89/186 (47%), Positives = 120/186 (64%), Gaps = 8/186 (4%) Frame = +2 Query: 68 APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247 AP I+LN+G +P + LGT + ESD+ R A ++ GYRH+DTA VY++E +V Sbjct: 5 APTIRLNNGREMPTLGLGTWKSF--ESDAYHSTRHA----LDVGYRHLDTAFVYENEAEV 58 Query: 248 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427 GQ I+E IA G+VTREE+FVTTKL H V A + SL LGL+Y+DLYL+H P+ Sbjct: 59 GQAISEKIAEGVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMPVG 118 Query: 428 TK-PDDSP-------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRP 583 K +DS ++DYL+TW+ M+ LGL RSIG+SNFNA Q R+++N IRP Sbjct: 119 QKFHNDSNVHGTLELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVLANCRIRP 178 Query: 584 GXNQIE 601 NQ+E Sbjct: 179 VVNQVE 184 >UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13; n=11; Theria|Rep: Aldo-keto reductase family 1 member C13 - Mus musculus (Mouse) Length = 323 Score = 155 bits (377), Expect = 6e-37 Identities = 81/195 (41%), Positives = 121/195 (62%), Gaps = 13/195 (6%) Frame = +2 Query: 56 MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235 M+ + C++LNDG+ IP ALG G KE + +A A++ GYRH+DTA YQ Sbjct: 1 MSSKQHCVKLNDGHLIP--ALGFGTYKPKEVPKSKSL-EAACLALDVGYRHVDTAYAYQV 57 Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415 EE++GQ I I G+V RE+LF+TTKLW + V PAL++SLKKL LDY+DLY++H Sbjct: 58 EEEIGQAIQSKIKAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMH 117 Query: 416 FPIATKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 562 +P+ K D+ D +D+ +TW+ +++ + GL +SIGVSNFN Q+ R++ Sbjct: 118 YPVPMKSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERIL 177 Query: 563 SNSYI--RPGXNQIE 601 + + +P NQ+E Sbjct: 178 NKPGLKYKPVCNQVE 192 >UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea) Length = 321 Score = 155 bits (375), Expect = 1e-36 Identities = 78/192 (40%), Positives = 126/192 (65%), Gaps = 10/192 (5%) Frame = +2 Query: 56 MAVQAPCIQLNDGNT-IPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQ 232 MA P + L+ G +P++ LGT + ++ VR+AV A++ GYRH DTAA+Y Sbjct: 1 MAFTIPEVPLSSGGRKMPVLGLGTAADPPVDPET---VRKAVTEALKLGYRHFDTAALYN 57 Query: 233 DEEQVGQGIAEAIANGLV-TREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYL 409 E+ +G IAEA+ GL+ +R+ELF+T+KLW R+ V PALQ++LK L L+YID+YL Sbjct: 58 SEQPLGDAIAEALGEGLIKSRDELFITSKLWCSDAHRENVEPALQKTLKNLKLEYIDMYL 117 Query: 410 IHFPIATKPDD------SPD--NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVS 565 IH+P+++KP + D +DY W+ M++ ++LGL ++IGVSNF+ +++ +++ Sbjct: 118 IHWPVSSKPGNYEYPIKKEDFLQMDYKSVWEAMEECQKLGLTKAIGVSNFSCKKLSDVLA 177 Query: 566 NSYIRPGXNQIE 601 N+ + P NQ+E Sbjct: 178 NAKVPPAVNQVE 189 >UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9 protein - Oryza sativa (Rice) Length = 337 Score = 153 bits (370), Expect = 4e-36 Identities = 86/198 (43%), Positives = 121/198 (61%), Gaps = 14/198 (7%) Frame = +2 Query: 50 AAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVY 229 AA A PC+ LN G+ +P++ GTG T ++ + A+ GYRH+DTAAVY Sbjct: 14 AAAATAVPCVTLNSGHAMPVLGFGTGSSTPPA-----DLAATIAHAVRLGYRHLDTAAVY 68 Query: 230 QDEEQVGQGIAEAIANGLV-TREELFVTTKL-WNDKHARDQVVPALQESLKKLGLDYIDL 403 E VG +AEA+ G V +R ELFVTTKL D H +VV AL+ESL +LGLDY+DL Sbjct: 69 GTEGAVGAAVAEAVRCGAVASRGELFVTTKLSMADAHP-PRVVAALRESLSRLGLDYVDL 127 Query: 404 YLIHFPIATKPDDSPDNI------------DYLETWQGMQDARQLGLARSIGVSNFNATQ 547 +LIH+P+A D+ + D W+GM++ +LGLARSIGVSNF+A + Sbjct: 128 FLIHWPVAIGKKDAAGELTWDDLSRGLVPFDMEGVWRGMEECHRLGLARSIGVSNFSAAK 187 Query: 548 ITRLVSNSYIRPGXNQIE 601 ++RL++ + + P NQ+E Sbjct: 188 MSRLLALAAVPPAVNQVE 205 >UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA19341-PA - Drosophila pseudoobscura (Fruit fly) Length = 315 Score = 153 bits (370), Expect = 4e-36 Identities = 86/192 (44%), Positives = 115/192 (59%), Gaps = 12/192 (6%) Frame = +2 Query: 62 VQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEE 241 + P L+ G +P+V LGT R + V QAV AI+ GYRH D A +Y +E Sbjct: 1 MSTPSFLLSSGRNMPMVGLGTWRSPP------EVVAQAVKDAIDIGYRHFDCAHIYGNEL 54 Query: 242 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 421 VG I E I GLVTR+ELF+T+KLWN H + V A + SL+ LG+DY+DLYL+H+P Sbjct: 55 HVGVAIREKIQEGLVTRDELFITSKLWNTFHKPELVRAACETSLRNLGIDYLDLYLMHWP 114 Query: 422 IATKPDDS-----PD-------NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVS 565 +A K D+ PD +IDYL+TW+ M+D GL +IGVSNFN QI RL+ Sbjct: 115 MAYKSGDNLYPTCPDTGKAVFEDIDYLDTWKAMEDLVDSGLVNAIGVSNFNEKQINRLLC 174 Query: 566 NSYIRPGXNQIE 601 + ++P QIE Sbjct: 175 LAKLKPVMLQIE 186 >UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|Rep: ENSANGP00000031808 - Anopheles gambiae str. PEST Length = 316 Score = 151 bits (367), Expect = 9e-36 Identities = 85/183 (46%), Positives = 112/183 (61%), Gaps = 12/183 (6%) Frame = +2 Query: 89 DGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEA 268 +GN+IP+ LGT +V QAV AI+ GYRHID A VYQ+E +VG+GIA Sbjct: 13 NGNSIPMFGLGTWNSPP------GQVAQAVKDAIDVGYRHIDCAHVYQNEHEVGEGIAAK 66 Query: 269 IANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK----- 433 IA G+V RE+LFVT+KLWN H D V A + +L+ L LDY+DLYLIH+P+ + Sbjct: 67 IAEGVVKREDLFVTSKLWNTFHRPDLVEGACKTTLQNLKLDYLDLYLIHWPVGYQEGTEL 126 Query: 434 ----PDDSP---DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXN 592 PD + DY++TW M+ GL R+IGVSNFNA Q+ R++ + I P N Sbjct: 127 FPMGPDGKTFLFSDADYVDTWPEMEKLVDAGLVRNIGVSNFNAKQVQRVLDVARIPPATN 186 Query: 593 QIE 601 QIE Sbjct: 187 QIE 189 >UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 324 Score = 151 bits (367), Expect = 9e-36 Identities = 83/192 (43%), Positives = 115/192 (59%), Gaps = 15/192 (7%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P ++LN+G +P + LGT DE +AV AI+ G+RHIDTA Y++E+ VG Sbjct: 7 PTVKLNNGLEMPAIGLGTSMSKG------DECCKAVMTAIDEGFRHIDTAYNYRNEDVVG 60 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430 + I I G+VTREELFVTTKLWN H D V A +SL+ LGLDY+DL+LIH P Sbjct: 61 RAIRAKIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSLEHLGLDYVDLFLIHMPFGY 120 Query: 431 K----------PDDSPDNI-----DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVS 565 + P D N+ DY++TW+ M+ + G SIGVSNFN+ Q+ R+++ Sbjct: 121 EFNGWDPEKRTPLDDNGNVLCSDDDYVDTWKAMEKLLESGRVHSIGVSNFNSEQLERILA 180 Query: 566 NSYIRPGXNQIE 601 N ++P NQ+E Sbjct: 181 NCRVKPVTNQVE 192 >UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18; n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member C18 - Mus musculus (Mouse) Length = 323 Score = 151 bits (366), Expect = 1e-35 Identities = 77/188 (40%), Positives = 118/188 (62%), Gaps = 13/188 (6%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 I+LNDG++IP++ GT A E + ++ AI+ G+ HID + +YQ+EE++GQ Sbjct: 8 IELNDGHSIPVLGFGT---YATEEHLKKKSMESTKIAIDVGFCHIDCSHLYQNEEEIGQA 64 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 I I +G V RE++F T+KLW+ H + V P+L+ SL+KL LDY+DLYLIHFP++ KP Sbjct: 65 ILSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKP 124 Query: 437 DDS--P---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 577 + P D +D +TW+ M+ + GLA+SIGVSNFN Q+ +++ + Sbjct: 125 GNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184 Query: 578 RPGXNQIE 601 +P NQ+E Sbjct: 185 KPVCNQVE 192 >UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus sp. (strain CC9311) Length = 336 Score = 151 bits (365), Expect = 2e-35 Identities = 75/183 (40%), Positives = 120/183 (65%), Gaps = 10/183 (5%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262 L++G+ +P++ LGTG+ +++ V ++V AI+ GYRHID A++Y +EE+VG I Sbjct: 24 LSNGDRMPLLGLGTGKSESRQ------VYKSVREAIKIGYRHIDCASIYGNEEEVGDAIR 77 Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 436 +AI N +TR EL++T+KLW++ H ++ V AL +SL+ LG+DY++LYLIH+P+ +P Sbjct: 78 DAIQNHEITRSELWITSKLWSNCHGKNHVEAALSQSLQNLGVDYLNLYLIHWPVGIRPEK 137 Query: 437 ------DD--SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXN 592 DD +P+ ETW+ M+ R GL + IGVSNF ++ +LVS+ +P N Sbjct: 138 TFAESVDDLLTPEESPISETWEAMESTRDKGLTKHIGVSNFTVKKLQQLVSHCKQKPEVN 197 Query: 593 QIE 601 Q+E Sbjct: 198 QVE 200 >UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 323 Score = 150 bits (364), Expect = 2e-35 Identities = 84/193 (43%), Positives = 115/193 (59%), Gaps = 11/193 (5%) Frame = +2 Query: 56 MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235 MA++ +LN G +IP +ALGT + S +EV AV AIE GYRHID A +Y + Sbjct: 1 MAMKQIFCKLNTGASIPAMALGTWQS------SKEEVGNAVRLAIELGYRHIDCAEIYGN 54 Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415 E ++G+ ++E + G V REELFVT+KLW D H D V+PA Q +LK L LDY+DLYLIH Sbjct: 55 EGEIGEALSEVLTEGKVKREELFVTSKLWCDSHHPDDVLPACQATLKNLQLDYLDLYLIH 114 Query: 416 FPIATK-----PDDSPDNI------DYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 562 P+A K P + I TWQ M+ GL ++IGVSNF+ ++ +L+ Sbjct: 115 IPVAFKKGVRLPHSIAEGIIGYTPEGVQNTWQAMEGLVAKGLCKAIGVSNFSVKRLNKLL 174 Query: 563 SNSYIRPGXNQIE 601 + I P NQ+E Sbjct: 175 ETASIVPACNQVE 187 >UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 320 Score = 147 bits (355), Expect = 3e-34 Identities = 76/183 (41%), Positives = 116/183 (63%), Gaps = 1/183 (0%) Frame = +2 Query: 56 MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235 M+ + P L++G +P + LGT + T +E ++ +R AV AGYRHIDTA +YQ+ Sbjct: 1 MSSKVPIFTLSNGVLMPSIGLGTWQMTGEEGKTV--IRNAVL----AGYRHIDTATLYQN 54 Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415 E Q+G +AE A G++ RE++F+TTK + + A D V AL+ SLK+L LDY+DLYL H Sbjct: 55 EHQIGDALAELFAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAH 114 Query: 416 FPIATKPDDS-PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXN 592 P +TK D S ++ + W+G + LGL ++IGVSNFN +QI R+++ + + Sbjct: 115 IPASTKDDGSFRSDVKVEDIWRGFEKVYGLGLTKAIGVSNFNESQIVRIMNIQKVPIHAS 174 Query: 593 QIE 601 Q+E Sbjct: 175 QLE 177 >UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase family; n=2; Entamoeba histolytica HM-1:IMSS|Rep: oxidoreductase, aldo/keto reductase family - Entamoeba histolytica HM-1:IMSS Length = 305 Score = 146 bits (353), Expect = 5e-34 Identities = 85/177 (48%), Positives = 110/177 (62%), Gaps = 4/177 (2%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262 LN+G IP + LGT EV +AV AI+ GYRHID A Y +E++VG GI Sbjct: 7 LNNGYKIPKLGLGTWMSAN------GEVGKAVEIAIKNGYRHIDCAKAYGNEKEVGDGIK 60 Query: 263 EAIANGLVTREELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP- 436 AIA G V REELFVTTKLW+ DKH D V PA ESLKKL L+Y+DLY+IH P+ Sbjct: 61 SAIAKGYVKREELFVTTKLWSTDKHKED-VRPACLESLKKLQLEYLDLYIIHIPLTADKK 119 Query: 437 --DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 + + + I ETW+ M+ + GL +SIGVSNFN ++ L++ + I+P NQ E Sbjct: 120 TGEFTEEIIPIEETWREMEKLVEEGLVKSIGVSNFNIKKLEELLAIAKIQPAVNQFE 176 >UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons|Rep: Chalcone reductase - Sesbania rostrata Length = 322 Score = 146 bits (353), Expect = 5e-34 Identities = 74/188 (39%), Positives = 125/188 (66%), Gaps = 11/188 (5%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYW-AIEAGYRHIDTAAVYQDEEQV 247 P + LN G+ +P++ G GT+ ES ++V +++ AI+ GYRH D+A+VY EE + Sbjct: 7 PEVLLNSGHKMPVI----GMGTSVESRPSNDVLASIFVDAIQVGYRHFDSASVYGTEEAI 62 Query: 248 GQGIAEAIANGLV-TREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424 G +++AI GL+ +R+E+F+T+K WN D +VPAL+ +LKKLG++Y+DLYLIH+P+ Sbjct: 63 GMAVSKAIEQGLIKSRDEVFITSKPWNTDAHHDLIVPALKTTLKKLGMEYVDLYLIHWPV 122 Query: 425 ATKPD-DSP-----DNI---DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 577 + D ++P +++ D TW+ M++ +LGLA+SIG+ N+ ++T+L+ + I Sbjct: 123 RLRHDLENPVIFSKEDLLPFDIEGTWKAMEECYRLGLAKSIGICNYGTKKLTKLLEIATI 182 Query: 578 RPGXNQIE 601 P NQ+E Sbjct: 183 PPAVNQVE 190 >UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA - Drosophila melanogaster (Fruit fly) Length = 322 Score = 145 bits (352), Expect = 6e-34 Identities = 79/193 (40%), Positives = 119/193 (61%), Gaps = 13/193 (6%) Frame = +2 Query: 62 VQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEE 241 + P L++G +P++ LGT R + V QAV AI+ GYRH D A +Y +E Sbjct: 1 MSTPNFLLSNGKNMPMLGLGTWRSPP------EVVTQAVKDAIDIGYRHFDCAHIYGNEA 54 Query: 242 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 421 QVG + E + G+VTR+ELF+T+KLWN H D V PA + S++ LG+ Y++LYL+H+P Sbjct: 55 QVGAALREKMDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWP 114 Query: 422 IATK----------PDDSP---DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 562 +A K PD + ++IDY++TW+ M++ GL ++IGVSNFN Q+ RL+ Sbjct: 115 MAYKSGSDNLYPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLL 174 Query: 563 SNSYIRPGXNQIE 601 S + ++P QIE Sbjct: 175 SVAKLKPVVLQIE 187 >UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo sapiens (Human) Length = 325 Score = 145 bits (351), Expect = 8e-34 Identities = 75/190 (39%), Positives = 117/190 (61%), Gaps = 12/190 (6%) Frame = +2 Query: 68 APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247 A C+ L+ G +P++ LGT + +V+ AV +A+ GYRHID AA+Y +E ++ Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEI 56 Query: 248 GQGIAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424 G+ + E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116 Query: 425 ATKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 571 A + D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI ++S + Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176 Query: 572 YIRPGXNQIE 601 +RP Q+E Sbjct: 177 SVRPAVLQVE 186 >UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: Aldehyde reductase - gamma proteobacterium HTCC2207 Length = 330 Score = 144 bits (350), Expect = 1e-33 Identities = 85/201 (42%), Positives = 116/201 (57%), Gaps = 20/201 (9%) Frame = +2 Query: 59 AVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDE 238 A+Q P ++++ ++P V LG + T D QAVY AI+ GYRH+D+AA Y +E Sbjct: 4 AIQVPGVKVSS-KSMPAVGLGLWKITQ------DSAAQAVYEAIKVGYRHLDSAADYGNE 56 Query: 239 EQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 418 +QVG+GIA AIA GL +REEL++TTKLWN H + V A + S+ LGLDYIDLYL+HF Sbjct: 57 QQVGEGIARAIAEGLCSREELWITTKLWNTYHRAEHVEAACRRSMDDLGLDYIDLYLVHF 116 Query: 419 PIATK--------------------PDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFN 538 PIA + P D + ETW M+ + GL R IGV N++ Sbjct: 117 PIALRYVDFNDRYPAEWIFDHSAEDPAMELDQVPLSETWGAMEQLVESGLVRQIGVCNYS 176 Query: 539 ATQITRLVSNSYIRPGXNQIE 601 A + L+S + I+P QIE Sbjct: 177 AVLLHDLMSYARIKPAMLQIE 197 >UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|Rep: Aldehyde reductase - Croceibacter atlanticus HTCC2559 Length = 316 Score = 143 bits (347), Expect = 3e-33 Identities = 77/186 (41%), Positives = 120/186 (64%), Gaps = 11/186 (5%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 ++ DG++IP + LGT + SD ++V++AV A+E GY+HID AA Y +E+ VG+ Sbjct: 4 LKFRDGDSIPSIGLGTWK-----SDP-EDVKKAVKIALENGYKHIDCAAAYDNEDAVGEA 57 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 E+ +G V RE++FVT+KLWN+ H ++ V+PAL+++LK L LDY+DLYL+H+P+A KP Sbjct: 58 FKESFESGNVKREDIFVTSKLWNNAHKKEDVIPALKKTLKDLNLDYLDLYLMHWPVAFKP 117 Query: 437 --DDSPD-NIDYL--------ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRP 583 + P+ + DYL ET M +A++ GL + +GVSNF+ ++ L P Sbjct: 118 SVNGFPEKDEDYLSLEEAPLHETLNAMIEAKKQGLIKHVGVSNFSKEKLESLKGKVEEMP 177 Query: 584 GXNQIE 601 NQ+E Sbjct: 178 EMNQVE 183 >UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep: GCY protein - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 295 Score = 143 bits (347), Expect = 3e-33 Identities = 80/191 (41%), Positives = 124/191 (64%), Gaps = 5/191 (2%) Frame = +2 Query: 44 LNAAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAA 223 +++ +++ LN+G IP + LGT +D D +A A++ GY+HIDTAA Sbjct: 1 MSSQLSINTKTYTLNNGLKIPAIGLGTWL-----ADEEDAAYKATLTALKNGYKHIDTAA 55 Query: 224 VYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDL 403 Y +E+QVG+ AIA+ V+R+E+FVTTKLWND+H + AL ESLKKLGL+Y+DL Sbjct: 56 AYGNEDQVGR----AIADSGVSRDEIFVTTKLWNDQHKDPE--GALDESLKKLGLEYVDL 109 Query: 404 YLIHFPIATKP-DDSP-DNIDYLETWQGMQDARQLG-LARSIGVSNFNATQITRLVSNSY 574 YLIH+P++ P + P D+ D+++TW+ +Q + G ++IGVSNFN ++ +L+++ Sbjct: 110 YLIHWPLSVDPKTEKPYDDYDFVDTWRNLQKIYKEGKKVKAIGVSNFNKKKLDKLLNSEG 169 Query: 575 IR--PGXNQIE 601 + P NQIE Sbjct: 170 VNVVPVINQIE 180 >UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid reductase A - Corynebacterium sp. (strain ATCC 31090) Length = 278 Score = 143 bits (347), Expect = 3e-33 Identities = 82/177 (46%), Positives = 111/177 (62%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P I LNDGN+IP LG G +D+ ++AV A+E GYRHIDTAA+Y +EE VG Sbjct: 4 PSIVLNDGNSIP--QLGYGVFKVPPADT----QRAVEEALEVGYRHIDTAAIYGNEEGVG 57 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430 IA A+G + R++LF+TTKLWND+H D+ A+ ESL KL LD +DLYL+H+P Sbjct: 58 AAIA---ASG-IARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWP--- 110 Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 +P +Y+ W+ M + R GL RSIGVSN + R+V+ + + P NQIE Sbjct: 111 ----TPAADNYVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVPAVNQIE 163 >UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Lactobacillus brevis ATCC 367|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 293 Score = 142 bits (345), Expect = 4e-33 Identities = 74/177 (41%), Positives = 114/177 (64%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P + +N+G+ IP + LG + D+ ++ + A+ WA+ AGYRHIDTAA Y +E+ VG Sbjct: 12 PDLPMNNGHQIPQLGLGVF-----QVDNAEDTKNAIKWALAAGYRHIDTAAYYGNEQWVG 66 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430 + I E+ V R+++FVT+KLWN D+ A QE+L KLGLDY+DLYLIH+P Sbjct: 67 EAIRESD----VPRDQIFVTSKLWNSVRGYDETQAAFQETLDKLGLDYLDLYLIHWP--- 119 Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 +P YL++W+ M+D + G ++IGVSNFN TQ+ ++++ ++P +QIE Sbjct: 120 ----AP---GYLDSWRAMEDLYKAGKIKNIGVSNFNQTQMADILAHGTVKPVVDQIE 169 >UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; Oryza sativa (japonica cultivar-group)|Rep: Putative uncharacterized protein - Oryza sativa subsp. japonica (Rice) Length = 288 Score = 142 bits (344), Expect = 6e-33 Identities = 74/188 (39%), Positives = 117/188 (62%), Gaps = 11/188 (5%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P L+ G +P V +GT +D V+ V AIEAGYRH DTAAVYQ E +G Sbjct: 2 PEAALSSGKPMPRVGMGTASFPLGATDP-STVKDVVLRAIEAGYRHFDTAAVYQTEAILG 60 Query: 251 QGIAEAIANGLV-TREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427 +AEA+ GLV +R+EL++T+KLW V+P+L+ +L+K+ ++Y+DLYLIHFP++ Sbjct: 61 DAVAEAVRAGLVASRDELYITSKLWVAHAHPGHVLPSLRRALRKMQMEYLDLYLIHFPVS 120 Query: 428 TKPDDSPDNIDYLE----------TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 577 + + P+++ Y + W+ M++ ++LGL ++IGVSNF+ ++ L+S + I Sbjct: 121 MRLAEDPESMTYSKDDLVMMDMEGVWKEMEECQRLGLTKAIGVSNFSCKKLETLLSFATI 180 Query: 578 RPGXNQIE 601 P NQ+E Sbjct: 181 SPAANQVE 188 >UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase 1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent oxidoreductase 1 - Oryza sativa subsp. japonica (Rice) Length = 321 Score = 142 bits (344), Expect = 6e-33 Identities = 77/179 (43%), Positives = 117/179 (65%), Gaps = 11/179 (6%) Frame = +2 Query: 98 TIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIAN 277 T+P V +GT A S ++ A+ AIE GYRH DTA +Y E VG+ +AEA+ Sbjct: 15 TMPRVGMGTA---AFPFTSSEDTTAAMLRAIELGYRHFDTARIYATEGCVGEAVAEAVRR 71 Query: 278 GLV-TREELFVTTKLW-NDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD--DS 445 GL+ +R ++FVT+K+W +D HA +VVPA +E+L+ LG+DY+DL L+H+P++ P D Sbjct: 72 GLIASRADVFVTSKIWCSDLHA-GRVVPAARETLRNLGMDYVDLLLVHWPVSLTPGNYDF 130 Query: 446 P-------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 P + D W+GM++ +LGLAR+IGVSNF+A ++ +L+S + +RP NQ+E Sbjct: 131 PFPKEVILPSFDMEGVWRGMEECHRLGLARAIGVSNFSAKKLEQLLSLAAVRPAVNQVE 189 >UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep: Aldehyde reductase - Salinibacter ruber (strain DSM 13855) Length = 321 Score = 141 bits (342), Expect = 1e-32 Identities = 72/185 (38%), Positives = 114/185 (61%), Gaps = 10/185 (5%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 I +G+ +P++ LGT + EV +AV A+EAGYRH+D A +Y++E +VG Sbjct: 4 ISFENGDEMPMIGLGTWKSPP------GEVYEAVTTALEAGYRHVDCAPIYKNETEVGAA 57 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK- 433 ++++ G + R++++VT+KLWN+ H D V PAL+++L L LD +DLYLIH+P+A + Sbjct: 58 LSDSFDAGGIRRDDVWVTSKLWNNAHHPDDVRPALEQTLSDLRLDALDLYLIHWPVALQP 117 Query: 434 -------PDD--SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPG 586 PDD SP+ + ETW M+ ++ GL R IGVSNF+ + ++ +RP Sbjct: 118 EVDFPESPDDFVSPEAVPLTETWAAMEALKKDGLVRHIGVSNFSVPNLQMILDAGEVRPE 177 Query: 587 XNQIE 601 NQ+E Sbjct: 178 MNQVE 182 >UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core eudicotyledons|Rep: Aldose reductase-like protein - Arabidopsis thaliana (Mouse-ear cress) Length = 316 Score = 141 bits (341), Expect = 1e-32 Identities = 75/183 (40%), Positives = 110/183 (60%), Gaps = 9/183 (4%) Frame = +2 Query: 80 QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259 +L G TIP++ +GT +I V QA I+ GYRH DTA +Y EE +G + Sbjct: 7 RLRCGETIPLLGMGTYCPQKDRESTISAVHQA----IKIGYRHFDTAKIYGSEEALGTAL 62 Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP- 436 +AI+ G V R++LFVT+KLW+ H + AL ++LK +GLDY+D YL+H+PI KP Sbjct: 63 GQAISYGTVQRDDLFVTSKLWSSDH--HDPISALIQTLKTMGLDYLDNYLVHWPIKLKPG 120 Query: 437 --------DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXN 592 D+ ++ ETWQGM+ ++GL RSIGVSNF++ +I L+ + + P N Sbjct: 121 VSEPIPKEDEFEKDLGIEETWQGMERCLEMGLCRSIGVSNFSSKKIFDLLDFASVSPSVN 180 Query: 593 QIE 601 Q+E Sbjct: 181 QVE 183 >UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropicalis|Rep: LOC594893 protein - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 345 Score = 140 bits (340), Expect = 2e-32 Identities = 84/210 (40%), Positives = 115/210 (54%), Gaps = 31/210 (14%) Frame = +2 Query: 65 QAPCIQLNDGNTIPIVALGT------------------GRGTAKESDSIDEVRQAVYWAI 190 Q IQL+DG +P+VA GT G E ID+VR A A+ Sbjct: 5 QGASIQLHDGRWMPVVAFGTFYPFTFPGDSQANPGHCAGTKHGTEKSFIDDVRVATKMAL 64 Query: 191 EAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQES 370 + GYRH+D A +Y E VGQ E A+G + RE+LF T+KLWN H V PAL+++ Sbjct: 65 DLGYRHVDGAFLYSSETGVGQAFREKFADGTLKREDLFYTSKLWNTFHQPHLVRPALEKT 124 Query: 371 LKKLGLDYIDLYLIHFPIATKPDDS--P---------DNIDYLETWQGMQDARQLGLARS 517 L L +DY+DLYLIH P++ KP + P D D L+TWQ +++ R GL +S Sbjct: 125 LSFLQMDYVDLYLIHMPMSFKPAEELFPKNEDGTCAFDQPDLLQTWQALEECRDAGLVKS 184 Query: 518 IGVSNFNATQITRLVSNSYI--RPGXNQIE 601 IGVSNFN Q+ +++ + +P NQIE Sbjct: 185 IGVSNFNRRQLEMILNKPGLKYKPVCNQIE 214 >UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid dehydrogenase - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 324 Score = 140 bits (340), Expect = 2e-32 Identities = 78/188 (41%), Positives = 114/188 (60%), Gaps = 13/188 (6%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 ++LNDG+ +P++ GT K S+ E V AI+ GYRHID A +Y +EE+VG+ Sbjct: 9 VELNDGHKMPVIGFGT-YAPPKFPKSLAEEGTKV--AIDVGYRHIDCAFLYGNEEEVGRA 65 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 I IA+G V RE++F T KLW+ H ++V PAL++SLK L LDY+DL++IH P+ KP Sbjct: 66 IRAKIADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPMEFKP 125 Query: 437 DDS--P---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 577 D P N D +TW+ ++ + GL RSIGVSNFN Q+ +++ + Sbjct: 126 GDDLFPADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIGVSNFNHKQLELILNMPGLKY 185 Query: 578 RPGXNQIE 601 +P NQ+E Sbjct: 186 KPVCNQVE 193 >UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep: Oxidoreductase - Lactobacillus plantarum Length = 286 Score = 139 bits (336), Expect = 5e-32 Identities = 80/172 (46%), Positives = 104/172 (60%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262 LN+G IPIV GT + T + D V A ++AGYRHIDTAA Y +EE VG+ Sbjct: 13 LNNGTKIPIVGFGTWQ-TPDGQVAYDSVLAA----LKAGYRHIDTAAAYGNEESVGK--- 64 Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 442 AIA+ V RE+LFVTTKLWN H D AL SL KLGLDY+DLYLIH+P D Sbjct: 65 -AIADSGVAREDLFVTTKLWNADHGYDAAKKALDTSLAKLGLDYVDLYLIHWPNPAAMRD 123 Query: 443 SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598 + + ++ +TW+ M++A AR+IGVSNF + L+ + + P NQI Sbjct: 124 NWEQLN-ADTWRAMEEAYTARKARAIGVSNFRPKHLDALLKTAKVVPAVNQI 174 >UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase 2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent oxidoreductase 2 - Oryza sativa subsp. japonica (Rice) Length = 322 Score = 139 bits (336), Expect = 5e-32 Identities = 76/179 (42%), Positives = 113/179 (63%), Gaps = 11/179 (6%) Frame = +2 Query: 98 TIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIAN 277 T+P + +GT A S +E A+ AIE GYRH DTA +Y E V + +AEA+ Sbjct: 17 TMPRIGMGTA---AFPFTSSEETTAALLRAIELGYRHFDTARLYATEGCVSEAVAEAVRR 73 Query: 278 GLV-TREELFVTTKLW-NDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP----- 436 GLV +R ++FVT+KLW +D HA +VVPA +E+L+ LG+DY+DL L+H+P P Sbjct: 74 GLVASRADVFVTSKLWCSDLHA-GRVVPAARETLRNLGMDYVDLLLVHWPATVAPGSYDF 132 Query: 437 ----DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 ++ D W+GM++ +LGLAR+IGVSNF+A ++ +L+S + +RP NQ+E Sbjct: 133 PFPKEEMAPAFDMEGVWRGMEECHRLGLARAIGVSNFSAKKLEQLLSFAVVRPAANQVE 191 >UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza sativa (Rice) Length = 323 Score = 138 bits (335), Expect = 7e-32 Identities = 75/186 (40%), Positives = 113/186 (60%), Gaps = 9/186 (4%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P + L G P+ A+G G + + S + R A A+E G+RH DTAA+Y E +G Sbjct: 5 PEVALRHGAGRPMPAVGVGTADSAAT-SPETKRGAALAALEVGFRHFDTAALYGTEAPLG 63 Query: 251 QGIAEAIANGLV-TREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427 + IAEA GLV +REE+FVTTKLW + V+P+L+ESL+ L ++Y+DLYL+H+PI+ Sbjct: 64 EAIAEATRRGLVASREEVFVTTKLWCTQCHPGLVLPSLRESLRNLQMEYVDLYLVHWPIS 123 Query: 428 TKPD--------DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRP 583 KP + D+ W+ M++ +LGLA++IGVSNF + +L++ + I P Sbjct: 124 VKPGPPMLPVKREDAVPFDFEGVWRAMEECHRLGLAKAIGVSNFTTKHLDKLLAVATIPP 183 Query: 584 GXNQIE 601 NQ+E Sbjct: 184 AVNQVE 189 >UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent 6'-deoxychalcone synthase - Glycine max (Soybean) Length = 315 Score = 138 bits (335), Expect = 7e-32 Identities = 72/191 (37%), Positives = 121/191 (63%), Gaps = 8/191 (4%) Frame = +2 Query: 53 AMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQ 232 A A++ P I + + + + G G+A + + ++A+ A++ GYRH DTAA Y Sbjct: 2 AAAIEIPTIVFPNSSAQQRMPV-VGMGSAPDFTCKKDTKEAIIEAVKQGYRHFDTAAAYG 60 Query: 233 DEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLI 412 E+ +G+ + EAI GLV+R++LFVT+KLW ++ V+PAL++SLK L L+Y+DLYLI Sbjct: 61 SEQALGEALKEAIHLGLVSRQDLFVTSKLWVTENHPHLVLPALRKSLKTLQLEYLDLYLI 120 Query: 413 HFPIATKPD--DSPDNI------DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSN 568 H+P++++P P + D W+ M++ ++LGL ++IGVSNF+ ++ L+S Sbjct: 121 HWPLSSQPGKFSFPIEVEDLLPFDVKGVWESMEECQKLGLTKAIGVSNFSVKKLQNLLSV 180 Query: 569 SYIRPGXNQIE 601 + IRP +Q+E Sbjct: 181 ATIRPVVDQVE 191 >UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; Lactobacillus|Rep: 2,5-didehydrogluconate reductase - Lactobacillus reuteri 100-23 Length = 288 Score = 138 bits (334), Expect = 9e-32 Identities = 82/174 (47%), Positives = 104/174 (59%), Gaps = 1/174 (0%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262 LN+G IP V GT R A D QAV AIE GYRHIDTAAVY +EE VG+GI Sbjct: 13 LNNGVKIPCVGYGTFRTPA------DVAEQAVKEAIETGYRHIDTAAVYGNEEAVGKGIK 66 Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-D 439 ++ G + RE+LFVT+KLWN +Q A QE+L +L +DY+DLYLIH+P K Sbjct: 67 DS---G-IKREDLFVTSKLWNTNRGYEQTKKAFQETLDRLQMDYLDLYLIHWPANEKQFG 122 Query: 440 DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 D I+ ETW+ M+D G R+IGVSNF I L+ + + P +QIE Sbjct: 123 DDAAKIN-AETWRAMEDLYNEGKIRAIGVSNFMPHHIAELMKTAKVAPAVDQIE 175 >UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium discoideum|Rep: Aldehyde reductase - Dictyostelium discoideum AX4 Length = 297 Score = 138 bits (334), Expect = 9e-32 Identities = 75/186 (40%), Positives = 114/186 (61%), Gaps = 9/186 (4%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P +L+ G+ IP+V G GT K ++ V +AV A++AGYRHID AAVY +E++VG Sbjct: 3 PSFKLSSGHKIPLV----GFGTWKAETTL--VGKAVEVALDAGYRHIDCAAVYLNEKEVG 56 Query: 251 QGIAEAIAN-GLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427 + + V RE++F+T+KLWN H ++ V PAL+ +L LGL Y+DLYL+H+P+A Sbjct: 57 EAFTKKFTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVHWPVA 116 Query: 428 ---TKPD-----DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRP 583 T D + + + ETW+ M+ GL +SIG+SNFN + ++S + I+P Sbjct: 117 FEYTSNDIQTSGSTQEFVSIRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYARIKP 176 Query: 584 GXNQIE 601 NQ+E Sbjct: 177 AANQVE 182 >UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae str. PEST Length = 319 Score = 138 bits (333), Expect = 1e-31 Identities = 76/198 (38%), Positives = 118/198 (59%), Gaps = 16/198 (8%) Frame = +2 Query: 56 MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235 M+ Q P ++ ++G IP+ LG G A++ ++ V++A I+ GYRHIDTA +Y++ Sbjct: 1 MSTQVPTVRFSNGYEIPV--LGYGTYLAQKGQCVELVKKA----IDLGYRHIDTAFLYEN 54 Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415 E ++GQ I + IA G++ RE++FVTTKLWN H V A + S L + YIDL+L+H Sbjct: 55 EVEIGQAIRDKIAEGVIRREDVFVTTKLWNTFHDPQHVEEAFRRSFDMLDIGYIDLFLMH 114 Query: 416 FPIAT----------KPDDSPDN-----IDYLETWQGMQD-ARQLGLARSIGVSNFNATQ 547 P+ +P D+ N +DY+ETW+ M+ G RSIG+SNFN+ Q Sbjct: 115 SPMGVQFSGYEYADMQPKDAAGNMLFSDVDYVETWKAMEKLVTAGGRVRSIGLSNFNSEQ 174 Query: 548 ITRLVSNSYIRPGXNQIE 601 I R++ + ++P NQ+E Sbjct: 175 IERILQIATVKPVNNQVE 192 >UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebacterium|Rep: Putative oxidoreductase - Corynebacterium diphtheriae Length = 290 Score = 137 bits (332), Expect = 2e-31 Identities = 73/177 (41%), Positives = 107/177 (60%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P I LNDG +P + GT + +E D+ VR A IE GYRHIDTA++Y++EE+VG Sbjct: 12 PTITLNDGTEMPAIGFGTYK--LREQDAYRAVRSA----IEVGYRHIDTASLYKNEEEVG 65 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430 + +A+AI G V R+ELF+TTK+WND H + QESL +LGLDYID ++H+P Sbjct: 66 RAVADAITAGEVARDELFITTKVWNDMHGDQLTQRSFQESLHRLGLDYIDCCMVHWP--- 122 Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 P Y+E++ + + LG +S+ V+NF + +V+ + I P NQ+E Sbjct: 123 ----WPQKGLYVESFAALAKIQGLGQLQSVAVANFYPEVLREIVAETGIAPVLNQVE 175 >UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: Aldehyde reductase - Leptospira interrogans Length = 278 Score = 136 bits (330), Expect = 3e-31 Identities = 75/175 (42%), Positives = 108/175 (61%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 I LN+G ++PI+ LG + + S E ++AV A+EAGYRHIDTA +Y +E VGQ Sbjct: 12 IMLNNGISMPILGLGVWK-----TKSGKECKEAVLNALEAGYRHIDTARIYDNEVDVGQA 66 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 I E+ G + R+E+F+TTKLWN D+ AL+ SL +LG+D++DLYLIHFP+ +K Sbjct: 67 IRES---G-IPRKEIFITTKLWNADQGSDKTRKALENSLDRLGIDFVDLYLIHFPVTSKR 122 Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 DS W+ ++ L ++IGVSN+ +T L+ NS I P NQ+E Sbjct: 123 MDS---------WKELEKLYHDKLCKAIGVSNYTIIHLTELLKNSQITPAVNQVE 168 >UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 322 Score = 136 bits (330), Expect = 3e-31 Identities = 75/192 (39%), Positives = 116/192 (60%) Frame = +2 Query: 26 ITLTCLLNAAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYR 205 +T + +++ ++ Q I+LN+G IP VALG + +D E A WA +AGYR Sbjct: 4 VTASGIISGNISTQR--IKLNNGQEIPQVALGVYKAP---NDGSTE--NACKWAFDAGYR 56 Query: 206 HIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLG 385 HID+AA Y +EE VG+ +AE V R E+F+T+KLW+ H D+ A+++SLKKL Sbjct: 57 HIDSAARYMNEESVGRALAEWTKENNVPRSEIFITSKLWDADH--DKAAAAIEDSLKKLN 114 Query: 386 LDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVS 565 +DY+D+YL+H P + LE W+ +++A G ++IGVSNF+ ++ L++ Sbjct: 115 VDYMDMYLMHSPGTMGAEKR------LEAWKALEEAVDAGKIKTIGVSNFDVEELDHLLA 168 Query: 566 NSYIRPGXNQIE 601 N I+P NQIE Sbjct: 169 NCRIKPAVNQIE 180 >UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate division TM7 genomosp. GTL1|Rep: Aldehyde reductase - candidate division TM7 genomosp. GTL1 Length = 299 Score = 136 bits (328), Expect = 5e-31 Identities = 75/187 (40%), Positives = 114/187 (60%), Gaps = 12/187 (6%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGR-GTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253 + L + T+P++ GT T +D ++ AI+AGYRHID A +Y +E++VG+ Sbjct: 4 LTLRNKQTLPLLGYGTWELPTGTTADLVET-------AIKAGYRHIDCAMIYGNEKEVGE 56 Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433 GI I G+V RE+LFVT+KLWN HA+ V A +++L LGLDY+DLYLIH+ +A + Sbjct: 57 GIRRTIDQGVVKREDLFVTSKLWNTDHAQVDVGVACRKTLNDLGLDYLDLYLIHWGVAFE 116 Query: 434 PDDSPDNID-----------YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 580 D+ + +D ETWQ M++ + GL +S+GV+NF A + L+S + I+ Sbjct: 117 HGDNLEPLDDDGVAKFSFISMKETWQAMEELVEQGLVKSMGVANFTAPMLLDLLSYAKIK 176 Query: 581 PGXNQIE 601 P +QIE Sbjct: 177 PAVHQIE 183 >UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 303 Score = 136 bits (328), Expect = 5e-31 Identities = 74/183 (40%), Positives = 113/183 (61%), Gaps = 8/183 (4%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 + LN+G++IP + LGT + T SD + ++ AV E GYR IDTA VY +E+ VGQ Sbjct: 2 LALNNGHSIPPIGLGTYKITG--SDGVAAIKSAV----EFGYRLIDTAFVYNNEQVVGQA 55 Query: 257 IAEAIANGL-VTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433 + E + G + RE++F+ +KL H + V + SL++LGLDY+DLYL+H P+A + Sbjct: 56 LREIFSQGNDINREDVFIVSKLGPTFHRPEAVEKGCRLSLERLGLDYVDLYLMHTPVAAR 115 Query: 434 PD-------DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXN 592 + D + LETW+ +++ ++ GL RSIGVSNFN Q+ +V++ IRP N Sbjct: 116 DSGDGNDRSEIDDEVTPLETWKALEECQRKGLVRSIGVSNFNEEQLMEIVTHGSIRPVVN 175 Query: 593 QIE 601 Q+E Sbjct: 176 QVE 178 >UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase); n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase) - Homo sapiens (Human) Length = 326 Score = 136 bits (328), Expect = 5e-31 Identities = 76/188 (40%), Positives = 110/188 (58%), Gaps = 13/188 (6%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 I L+DGN+IPI+ LGT + +S +V AI+ GYRHID A +YQ+E +VG+ Sbjct: 10 IPLSDGNSIPIIGLGTY--SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEA 67 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 I E IA G V RE++F KLW H + V P L+ +L+ L LDY+DLY+I P+A KP Sbjct: 68 IREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKP 127 Query: 437 DDS----PDNIDYL-------ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 577 D +N +L TW+ M+ + GL +S+GVSNFN Q+ +++ + Sbjct: 128 GDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKH 187 Query: 578 RPGXNQIE 601 +P NQ+E Sbjct: 188 KPVSNQVE 195 >UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20; Corynebacterineae|Rep: 2,5-didehydrogluconate reductase - Mycobacterium sp. (strain KMS) Length = 283 Score = 135 bits (326), Expect = 9e-31 Identities = 77/181 (42%), Positives = 112/181 (61%) Frame = +2 Query: 59 AVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDE 238 A P + LNDG++IP++ LG G + E++ ++V A+EAGYR IDTAAVY +E Sbjct: 8 AAGIPSVSLNDGHSIPVLGLGVGELSEAEAE------RSVAAALEAGYRLIDTAAVYGNE 61 Query: 239 EQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 418 VG+ + A+G + REE++VTTKL A + SL++LGLDY+DLYLIH+ Sbjct: 62 AAVGRAVN---ASG-IPREEIYVTTKLAVADQGFGTSQDAARASLERLGLDYVDLYLIHW 117 Query: 419 PIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598 P D+ Y+++W G+ A+Q G+ARSIGV NFNA ++ ++ S+ P NQI Sbjct: 118 PAG-------DHGKYIDSWGGLMKAKQDGVARSIGVCNFNAEHLSNIIDLSFFTPAINQI 170 Query: 599 E 601 E Sbjct: 171 E 171 >UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: Aldose reductase - Mus musculus (Mouse) Length = 316 Score = 134 bits (325), Expect = 1e-30 Identities = 75/188 (39%), Positives = 111/188 (59%), Gaps = 13/188 (6%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 ++LN+G +P + LGT + +V +AV AI+ GYRHID A VYQ+E++VG Sbjct: 5 LELNNGTKMPTLGLGTWKSPP------GQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVA 58 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 + E + +V R++LF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP Sbjct: 59 LQEKLKEQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKP 118 Query: 437 -------DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 577 D S P + D+++TW M+ GL ++IGVSNFN QI R+++ + Sbjct: 119 GPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKY 178 Query: 578 RPGXNQIE 601 +P NQIE Sbjct: 179 KPAVNQIE 186 >UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Photorhabdus luminescens subsp. laumondii Length = 292 Score = 134 bits (324), Expect = 2e-30 Identities = 76/177 (42%), Positives = 109/177 (61%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P I+L DGN +P + LG+ SD ++ + ++ A++ GYR IDTAA+Y +E+ VG Sbjct: 5 PIIRLADGNHMPQLGLGSWA-----SDD-QQIAETIHAALDIGYRAIDTAAIYNNEKGVG 58 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430 + E + RE++FVTTKLWND+H + AL ESL+KL LDY+DLYLIH+P Sbjct: 59 NALQETD----IPREDIFVTTKLWNDRHLDARA--ALTESLEKLQLDYVDLYLIHWP--- 109 Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 +P Y+ WQ + + ++ GL RSIGVSNF I RL++ + + P NQIE Sbjct: 110 ----APPQDQYVGAWQQLIELQKEGLIRSIGVSNFQPEHIQRLINETGVHPVINQIE 162 >UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH - Aspergillus niger Length = 323 Score = 134 bits (323), Expect = 2e-30 Identities = 81/184 (44%), Positives = 110/184 (59%), Gaps = 11/184 (5%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262 +N G IP V GT + AK EV AV A+ GYRHID AA+Y++E +VG GI Sbjct: 9 INTGAKIPAVGFGTWQ--AKPL----EVENAVEVALREGYRHIDCAAIYRNETEVGNGIR 62 Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 442 ++ G V REE+F+T KLWN KHA + V PAL ++L+ LG+ Y+DLYL+H+P A K D Sbjct: 63 KS---G-VPREEIFITGKLWNTKHAPEDVEPALDKTLQDLGVAYLDLYLMHWPCAFKGGD 118 Query: 443 -----SPD------NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGX 589 + D NIDY+ T++ M+ G R+IGVSNFN ++ L+ + P Sbjct: 119 KWFPLNDDGVFDLANIDYITTYRAMEKLLATGKVRAIGVSNFNIRRLEELLGQVSVVPAV 178 Query: 590 NQIE 601 NQIE Sbjct: 179 NQIE 182 >UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent D-sorbitol-6-phosphate dehydrogenase - Malus domestica (Apple) (Malus sylvestris) Length = 310 Score = 133 bits (322), Expect = 3e-30 Identities = 75/190 (39%), Positives = 107/190 (56%), Gaps = 15/190 (7%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 + L+ G +P++ LG R DE+++ + AI+ GYRH D AA Y+ E VG+ Sbjct: 4 VTLSSGYEMPVIGLGLWRLEK------DELKEVILNAIKIGYRHFDCAAHYKSEADVGEA 57 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 +AEA GLV REELF+TTK+WN H VV A + SL+KL +DY+DLYL+H+P+ TK Sbjct: 58 LAEAFKTGLVKREELFITTKIWNSDHG--HVVEACKNSLEKLQIDYLDLYLVHYPMPTKH 115 Query: 437 D---------------DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 571 + D I +TW+GM+ LGL RSIG+SN+ ++ S Sbjct: 116 NAIGKTASLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSNYELFLTRDCLAYS 175 Query: 572 YIRPGXNQIE 601 I+P +Q E Sbjct: 176 KIKPAVSQFE 185 >UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: Aldehyde reductase - Opitutaceae bacterium TAV2 Length = 347 Score = 133 bits (321), Expect = 4e-30 Identities = 73/204 (35%), Positives = 113/204 (55%), Gaps = 13/204 (6%) Frame = +2 Query: 29 TLTCLLNAAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRH 208 T T L + P L G +P + +GT + + EV +VY A E GYRH Sbjct: 3 TETATLAPIDPAKIPQRTLASGARMPAIGMGT---FGSDHAAPGEVAASVYAAAELGYRH 59 Query: 209 IDTAAVYQDEEQVGQGIAEAI-ANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLG 385 D AAVY +E ++G + +N + RE+L++T+KLWNDKHA V+PA ++SL+ LG Sbjct: 60 FDCAAVYSNEREIGATFRRILTSNTGIRREDLWITSKLWNDKHAEADVIPAFEKSLRDLG 119 Query: 386 LDYIDLYLIHFPI-----------ATKPDDSP-DNIDYLETWQGMQDARQLGLARSIGVS 529 LDY+DLYLIH+P + PD P + ++++TW+ ++ GL R IG S Sbjct: 120 LDYLDLYLIHWPFPNFHPPGCDVSSRSPDARPYIHAEFMKTWRQLETLHDRGLVRHIGTS 179 Query: 530 NFNATQITRLVSNSYIRPGXNQIE 601 N ++ L+ ++ +RP N++E Sbjct: 180 NMTIAKLQLLLRDARVRPAVNEME 203 >UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Yersinia pestis Length = 277 Score = 133 bits (321), Expect = 4e-30 Identities = 77/177 (43%), Positives = 103/177 (58%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P I+L DG +P + LG + SI E AV A+E GYR IDTAA+Y++EE Sbjct: 5 PLIKLYDGRLMPQLGLGVWQA------SIQETELAVSKALEVGYRSIDTAAIYKNEE--- 55 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430 G+ +A+ V R+ELF+TTKLWND Q AL+ SL+KL LDY+DLYLIH+P Sbjct: 56 -GVGKALKAAAVARDELFITTKLWNDDQHNPQ--QALETSLQKLQLDYVDLYLIHWP--- 109 Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 P Y+ W+ + ++ GL RSIGV NF+ + RL+ + I P NQIE Sbjct: 110 ----DPKQDHYVSAWRELVTLKEQGLIRSIGVCNFHIPHLQRLIDETGIAPTVNQIE 162 >UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotina|Rep: Aldehyde reductase - Coccidioides posadasii Length = 314 Score = 132 bits (320), Expect = 5e-30 Identities = 76/193 (39%), Positives = 114/193 (59%), Gaps = 11/193 (5%) Frame = +2 Query: 56 MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235 MA + +LN G IP + GT + + D AV A+ AGYRHIDTAAVY Sbjct: 1 MASRHTTFRLNTGEDIPAIGFGTWQDENAQED-------AVLTALSAGYRHIDTAAVYGT 53 Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415 E+ +G+ A+A ++R+ELF+T+KLWN+KH + V A+ +SLK L +DY+DLYL+H Sbjct: 54 EKAIGR----ALARSRLSRDELFITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMH 109 Query: 416 FPIATK------PDDSPDN-----IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 562 +P A P DS N IDY++T++ M+ + G ++IG+SNF+ ++ RL+ Sbjct: 110 WPAAFAPGDDMFPKDSQGNSKTVDIDYVDTYKAMEKLVKSGKTKAIGISNFSKGEMERLL 169 Query: 563 SNSYIRPGXNQIE 601 + I P Q+E Sbjct: 170 ESCSIVPAVMQME 182 >UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: Aldose reductase - Homo sapiens (Human) Length = 316 Score = 132 bits (320), Expect = 5e-30 Identities = 76/186 (40%), Positives = 109/186 (58%), Gaps = 13/186 (6%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262 LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60 Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 436 E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120 Query: 437 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 583 D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180 Query: 584 GXNQIE 601 NQIE Sbjct: 181 AVNQIE 186 >UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7; cellular organisms|Rep: Prostaglandin f synthase, putative - Leishmania major Length = 279 Score = 132 bits (319), Expect = 6e-30 Identities = 72/182 (39%), Positives = 110/182 (60%) Frame = +2 Query: 56 MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235 MAV+ + L++G +P LG G AK+ + + ++ WA+ AGYRH+DTA Y++ Sbjct: 1 MAVKCTHVTLSNGVQVP--QLGIGTWEAKDGNEVVNIK----WAVNAGYRHVDTAHYYKN 54 Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415 E+ VGQGI+E G V R ++FVTTKLWN H + + A ++S + LG++Y+DLYLIH Sbjct: 55 EKGVGQGISEC---G-VPRSDIFVTTKLWNYDHGYESALAAFEQSRQALGVEYVDLYLIH 110 Query: 416 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQ 595 +P P N Y+ETW+ + ++ R+IGVSNF + L++N + P NQ Sbjct: 111 WP-------GP-NRSYIETWRAFEKLYEMKKVRAIGVSNFEPHHLDDLLANCTVPPMVNQ 162 Query: 596 IE 601 +E Sbjct: 163 VE 164 >UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaster|Rep: CG40064-PA - Drosophila melanogaster (Fruit fly) Length = 361 Score = 132 bits (318), Expect = 8e-30 Identities = 66/155 (42%), Positives = 96/155 (61%), Gaps = 12/155 (7%) Frame = +2 Query: 173 AVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVV 352 AV+ AIE G+RH DTA Y++E+++G+ + I G ++RE +F+TTKLWN H V Sbjct: 49 AVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMGNISRENIFLTTKLWNTHHDPRDVR 108 Query: 353 PALQESLKKLGLDYIDLYLIHFPIATK--------PDDSPD----NIDYLETWQGMQDAR 496 ++ L+ LG YIDLYL+HFP+ K P + IDYL+TW+ M++ Sbjct: 109 RICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMSGDELQTVEIDYLDTWRAMENLV 168 Query: 497 QLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 +LG+ RSIG+SNFN QI R++ S +P NQ+E Sbjct: 169 KLGMVRSIGLSNFNMEQIQRIIQCSSSKPVVNQVE 203 >UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebacterium jeikeium K411|Rep: Putative oxidoreductase - Corynebacterium jeikeium (strain K411) Length = 285 Score = 131 bits (317), Expect = 1e-29 Identities = 77/177 (43%), Positives = 102/177 (57%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P +++NDG T P LG G + D+ VR A IE GYRHIDTAA+Y +EE VG Sbjct: 9 PTLEMNDGKTTP--QLGLGVWQLSDEDTYTSVRAA----IETGYRHIDTAAIYGNEEAVG 62 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430 + +A+A+ G V REELF+TTKLWN A + A ES KKLG+DY+DLYL+H+P Sbjct: 63 RAVADAVKAGDVQREELFITTKLWNADQACGK--EAFAESQKKLGMDYVDLYLLHWP--- 117 Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 P +++ + M + +Q G A SIGV NF + L + P NQIE Sbjct: 118 ----CPQADSFVQAYDSMAEIQQSGGATSIGVCNFYPEALDALKQAGH-TPAVNQIE 169 >UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 337 Score = 131 bits (317), Expect = 1e-29 Identities = 76/180 (42%), Positives = 102/180 (56%), Gaps = 5/180 (2%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 I +ND N + I +G G A+ + EVR AV A+ AGY H+D AA Y +E +VG+ Sbjct: 6 ILVNDANGLRIPRVGLGTWKARPN----EVRDAVRDALGAGYAHVDCAAAYANESEVGEA 61 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 + EA G RE++FVT+KLWND+ V AL +L LG+ Y+DLYLIH+P+A K Sbjct: 62 LREAFERGDAKREDVFVTSKLWNDRRRPRDVREALMTTLNDLGVGYLDLYLIHWPVAWKR 121 Query: 437 DD--SPD-NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSN--SYIRPGXNQIE 601 PD E W ++ GL R IGVSNFN Q+ L + + I+P NQIE Sbjct: 122 GTVLQPDAEASIAECWSELERCVADGLVRHIGVSNFNEAQLAALCDDPRTKIQPACNQIE 181 >UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 333 Score = 130 bits (315), Expect = 2e-29 Identities = 70/188 (37%), Positives = 110/188 (58%), Gaps = 13/188 (6%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 + L G+ +P+V LGT + A DEV A+ A++AGYRH D A +Y +E++VG Sbjct: 5 VTLPSGHAMPLVGLGTWKLKA------DEVAGAIGAAVDAGYRHFDCALIYGNEKEVGVA 58 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA--- 427 + EA+ + RE++F+TTK+WN HA++ V SL L LDYIDLY++H+P+ Sbjct: 59 LREAMQRLGLKREDVFITTKVWNTFHAKEDVAECFNRSLTDLQLDYIDLYIMHWPLGFQN 118 Query: 428 ---------TKPDDSP-DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 577 T+ D ++ YLETW M+D + G +S+G+SNFN+ Q+ ++ +S + Sbjct: 119 LGPTVMFPRTETGDIVYSDVHYLETWSAMEDLVKTGKCKSLGLSNFNSKQLDDVLQHSTV 178 Query: 578 RPGXNQIE 601 P Q+E Sbjct: 179 PPSVLQVE 186 >UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: Aldehyde reductase 1 - Sporobolomyces salmonicolor Length = 323 Score = 130 bits (315), Expect = 2e-29 Identities = 76/189 (40%), Positives = 109/189 (57%), Gaps = 16/189 (8%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262 LN G ++ +V GT + EV Q V AIE GYRH+D A VY ++ +VG I Sbjct: 7 LNTGASLELVGYGTWQAAP------GEVGQGVKVAIETGYRHLDLAKVYSNQPEVGAAIK 60 Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD- 439 EA G V RE+LF+T+KLWN+ H +QV PAL ++LK+LGL+Y+DLYLIH+P+A P+ Sbjct: 61 EA---G-VKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHWPVAFPPEG 116 Query: 440 DSPDN---------------IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 574 D N + ++TW+ M G ++IGVSNF+A + ++ + Sbjct: 117 DITQNLFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKAIGVSNFDAKMVDAIIEATG 176 Query: 575 IRPGXNQIE 601 + P NQIE Sbjct: 177 VTPSVNQIE 185 >UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium discoideum AX4 Length = 321 Score = 130 bits (314), Expect = 2e-29 Identities = 76/190 (40%), Positives = 110/190 (57%), Gaps = 16/190 (8%) Frame = +2 Query: 80 QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259 +LNDGN IP + LGT S++ EV A+ A++ GYRHID AA Y +E+ +G + Sbjct: 18 KLNDGNQIPSIGLGT-----YYSENPGEVGDAINNALKNGYRHIDGAAFYGNEKVIGNSL 72 Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA---T 430 E G + RE++F T+KLWN H + VV ++++ LG+ Y+DLYLIH+PIA + Sbjct: 73 KEIFKEGEIKREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPIAFENS 132 Query: 431 KP--------DDSPDN-----IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 571 P D N + ETWQ M+ +LGL +SIGVSNFN + L++ + Sbjct: 133 NPLGLTIEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVDLLTYA 192 Query: 572 YIRPGXNQIE 601 I+P NQ+E Sbjct: 193 KIKPVVNQVE 202 >UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 700755|Rep: YvgN - Psychroflexus torquis ATCC 700755 Length = 280 Score = 130 bits (313), Expect = 3e-29 Identities = 79/175 (45%), Positives = 103/175 (58%), Gaps = 2/175 (1%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262 LNDGN IPIV GT + A E + I ++++ A+ GYR IDT A+YQ+EE VG+ I Sbjct: 5 LNDGNRIPIVGFGTYK--ANEEEGIKSIQKS---ALTLGYRLIDTVAIYQNEEAVGKAIK 59 Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP--IATKP 436 A G V REE+FVTTKLW + Q AL ESL+KL L+YIDLYLIH+P Sbjct: 60 ---ARG-VLREEIFVTTKLWRENLGYKQTRIALDESLRKLDLNYIDLYLIHWPANAINYK 115 Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 D N D TW+ M++ + G +S+GVSNF + L + + P NQIE Sbjct: 116 DWQKTNAD---TWRAMEELQAEGKIKSLGVSNFWPEHLEALFQTAKVSPSVNQIE 167 >UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG03517.1 - Gibberella zeae PH-1 Length = 364 Score = 129 bits (312), Expect = 4e-29 Identities = 73/196 (37%), Positives = 118/196 (60%), Gaps = 3/196 (1%) Frame = +2 Query: 23 IITLTCLLNAAMAVQAPCIQLNDGNTI-PIVALGTGRGTAKESDSIDEVRQAVYWAIEAG 199 ++T T L A A + N T+ I A G G A + V AV +A++ G Sbjct: 31 LVTYTILSIATSFGPAEMPEFNKNETVRDIPAFGLGTWLAGKG----VVVPAVEYALKGG 86 Query: 200 YRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKK 379 YRHIDTA ++++E++VG+GI A+G V+R+E++VT KLWN H + V A++ S+ Sbjct: 87 YRHIDTALIWRNEDEVGKGIK---ASG-VSRDEIWVTGKLWNTDHRPELVRKAIETSIAN 142 Query: 380 LGLDYIDLYLIHFPIATKPD--DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQIT 553 LG++Y+DLYLIH+P+A P+ D +N ++TW+ M++ + GL R+IG SNF I Sbjct: 143 LGVEYLDLYLIHYPVAWVPETRDVDNNTSLIDTWKAMEELVRAGLTRNIGFSNFAPKDIN 202 Query: 554 RLVSNSYIRPGXNQIE 601 +++ + I+P ++ E Sbjct: 203 KILKIASIQPYAHEFE 218 >UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; Schizosaccharomyces pombe|Rep: Probable oxidoreductase C26F1.07 - Schizosaccharomyces pombe (Fission yeast) Length = 321 Score = 129 bits (311), Expect = 6e-29 Identities = 74/184 (40%), Positives = 113/184 (61%), Gaps = 11/184 (5%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262 L DG+ IP + LGT R ++ + AV A++ GYRHID AA+Y +E++VG GI Sbjct: 18 LADGSKIPGLGLGTWRSEPNQT------KNAVKTALQYGYRHIDAAAIYGNEDEVGDGIK 71 Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK--- 433 E+ G V R++++VT+KLW + HA + V AL+++LK L LDY+D YLIH+P++ K Sbjct: 72 ES---G-VPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGE 127 Query: 434 ---PDDSPDNIDY-----LETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGX 589 P D N+ Y ETW+ M+ + G R IG+SNFN T + R++ + ++P Sbjct: 128 DKFPKDKDGNLIYEKNPIEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAKVKPAV 187 Query: 590 NQIE 601 +Q+E Sbjct: 188 HQME 191 >UniRef50_P22045 Cluster: Probable reductase; n=101; cellular organisms|Rep: Probable reductase - Leishmania major Length = 284 Score = 129 bits (311), Expect = 6e-29 Identities = 72/180 (40%), Positives = 107/180 (59%) Frame = +2 Query: 62 VQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEE 241 V + L++G +P LG + A E AV WA+ AGYRHIDTAA+Y++EE Sbjct: 4 VDKAMVTLSNGVKMPQFGLGVWQSPAGEV-----TENAVNWALCAGYRHIDTAAIYKNEE 58 Query: 242 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 421 VG G+ A+G V RE++F+TTKLWN + + + A +ES +KLG+DYIDLYLIH+P Sbjct: 59 SVGAGLR---ASG-VPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWP 114 Query: 422 IATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 K S + YL++W+ + + R+IGVSNF+ + +++ + P NQ+E Sbjct: 115 -RGKDILSKEGKKYLDSWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTPMVNQVE 173 >UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep: Protein GCY - Saccharomyces cerevisiae (Baker's yeast) Length = 312 Score = 128 bits (309), Expect = 1e-28 Identities = 80/196 (40%), Positives = 121/196 (61%), Gaps = 21/196 (10%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 + LN G IP + LGT + +KE+D+ +AV A++ GYRHIDTAA+Y++E+QVGQ Sbjct: 12 LSLNTGAQIPQIGLGTWQ--SKENDAY----KAVLTALKDGYRHIDTAAIYRNEDQVGQ- 64 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP----- 421 AI + V REE+FVTTKLW +H +V AL +SLK+LGLDY+DLYL+H+P Sbjct: 65 ---AIKDSGVPREEIFVTTKLWCTQHHEPEV--ALDQSLKRLGLDYVDLYLMHWPARLDP 119 Query: 422 ----------IATKPDDSP----DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRL 559 + TK D S N ++++TW+ MQ+ + G +++GVSNF+ + L Sbjct: 120 AYIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDL 179 Query: 560 VSN--SYIRPGXNQIE 601 +++ + + P NQ+E Sbjct: 180 LASQGNKLTPAANQVE 195 >UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus (Mouse) Length = 316 Score = 128 bits (308), Expect = 1e-28 Identities = 77/191 (40%), Positives = 109/191 (57%), Gaps = 13/191 (6%) Frame = +2 Query: 68 APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247 A + L G +PIV LGT + + VR+AV AI+AGYRHID A VYQ+E +V Sbjct: 2 AAFVTLLTGAKMPIVGLGTWKSPPAK------VREAVKVAIDAGYRHIDCAYVYQNESEV 55 Query: 248 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427 G+ I E I V RE+LF+ +KLW+ + V A Q +L L LDY+DLYLIH+P Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQG 115 Query: 428 TK------PDDSPDNI-----DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 574 + P D +I +L+ W+ M++ GL +++GVSNFN QI RL++ Sbjct: 116 FQSGNVFLPTDDKGSILSSKYTFLDAWEAMEELVDQGLVKALGVSNFNHFQIERLLNKPG 175 Query: 575 I--RPGXNQIE 601 + +P NQ+E Sbjct: 176 LKHKPVTNQVE 186 >UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Orconectes limosus|Rep: Aldoketoreductase-like protein - Orconectes limosus (Spinycheek crayfish) Length = 336 Score = 128 bits (308), Expect = 1e-28 Identities = 73/194 (37%), Positives = 102/194 (52%), Gaps = 10/194 (5%) Frame = +2 Query: 50 AAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVY 229 A + P I LN G+ IP++ LGTG S + V + A+E GYRH D+AA Y Sbjct: 5 AGAMTKIPTILLNSGSHIPVMGLGTGSLGRNGKMSEEAVTAVLETALECGYRHFDSAAYY 64 Query: 230 QDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYL 409 +E +GQ + I+ G V REELF+TTKL + V LQ+SL L L Y+DLYL Sbjct: 65 GNEAIIGQVLRRWISEGKVKREELFITTKLPTRGNREKDVARFLQKSLDNLRLPYVDLYL 124 Query: 410 IHFPIATKPDD----SPDNI------DYLETWQGMQDARQLGLARSIGVSNFNATQITRL 559 +H+P D S D + D W+ M+ G ++IG+SNFNA Q+ R+ Sbjct: 125 VHYPCGILDTDRERLSADEVTVDPTTDIHAIWRAMEAQLAAGKTKNIGLSNFNADQVQRI 184 Query: 560 VSNSYIRPGXNQIE 601 + +RP Q+E Sbjct: 185 IKGCQVRPAVLQVE 198 >UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=3; Lactobacillales|Rep: Aldo/keto reductase of diketogulonate reductase family - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 292 Score = 127 bits (307), Expect = 2e-28 Identities = 69/145 (47%), Positives = 90/145 (62%) Frame = +2 Query: 167 RQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQ 346 +QAV AI+ GYR IDTAA Y +E +VG+ I EAI G+V REELFVT+K+W + Q Sbjct: 29 KQAVLDAIKTGYRLIDTAASYGNEREVGEAILEAINQGIVKREELFVTSKMWVQDVSAQQ 88 Query: 347 VVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGV 526 A+Q SL++L LDY+DLYLIH P D W+ M+ A + G ++IGV Sbjct: 89 ATAAIQSSLQRLNLDYLDLYLIHQPYN----------DVFGAWRAMESAYRSGQLKAIGV 138 Query: 527 SNFNATQITRLVSNSYIRPGXNQIE 601 SNF+ Q+T L S I+P NQIE Sbjct: 139 SNFDIAQLTNLAEFSDIKPMLNQIE 163 >UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 316 Score = 127 bits (307), Expect = 2e-28 Identities = 76/186 (40%), Positives = 105/186 (56%), Gaps = 11/186 (5%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 I +G T+P + GT R S +EV +A+ A+EAGYRHIDTA VY +E+ +G+ Sbjct: 7 ITFENGTTMPALGFGTWRA------SDEEVEKALNEALEAGYRHIDTAPVYLNEKTIGKV 60 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 + E + G VTR+ELF+ TKL V L+ SL L L+Y+DLY +H P Sbjct: 61 LKEWMDAGKVTRDELFIVTKLPPHGTRASTVEKFLKNSLDDLQLEYVDLYHVHVPFTVPE 120 Query: 437 DDSP----DNIDYLET-------WQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRP 583 D P D + LET W+ M++ + GLAR+IG+SNFN QI R++ N I+P Sbjct: 121 VDGPFLVEDGLIVLETTTDHVALWKAMEEVYEAGLARNIGLSNFNQRQIQRILDNCQIKP 180 Query: 584 GXNQIE 601 QIE Sbjct: 181 ANLQIE 186 >UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=10; Trichomonas vaginalis|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 312 Score = 127 bits (307), Expect = 2e-28 Identities = 72/175 (41%), Positives = 104/175 (59%), Gaps = 16/175 (9%) Frame = +2 Query: 125 GRGTAKESDSIDEVRQAVYWAIE-AGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREEL 301 G GT +D +++ A+++AIE G RHIDTA Y ++ +G+ + E A G + RE++ Sbjct: 7 GFGTYLANDPA-KLKAALHYAIEECGVRHIDTAFAYYNQNVIGETLKEIFAKGKIKREDM 65 Query: 302 FVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK----------PDDSP- 448 F+TTKLW H +D V P L E+L +L L Y+DL+LIH PIA K P D Sbjct: 66 FITTKLWCTHHRKDLVEPELHENLAQLQLSYVDLFLIHQPIAFKSLPAKDGTMMPKDEKG 125 Query: 449 ----DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 + ID LET+ M++ ++ GL R IGVSNF+ Q+ R+ N I+P NQ+E Sbjct: 126 KIQYEQIDILETYHAMEECQKKGLTRHIGVSNFSIEQLERIWFNCEIKPYANQVE 180 >UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep: Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 289 Score = 127 bits (306), Expect = 2e-28 Identities = 63/150 (42%), Positives = 89/150 (59%), Gaps = 11/150 (7%) Frame = +2 Query: 185 AIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQ 364 AI AGYRHIDTA Y++E VG I I G++ R+++F+ +KLW HA + + Sbjct: 9 AIAAGYRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPEDIPVCFN 68 Query: 365 ESLKKLGLDYIDLYLIHFPIATK-------PDDS----PDNIDYLETWQGMQDARQLGLA 511 +SL L LDY+D YL+HFP+ K P+ +IDY++ W+GM+ + G Sbjct: 69 KSLSDLQLDYLDQYLVHFPVGLKKVGDELFPERDGKILTTDIDYVDVWRGMEALKATGKV 128 Query: 512 RSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 +SIGVSNF QI RL+S + I P NQ+E Sbjct: 129 KSIGVSNFTMEQIDRLLSVAKIPPAVNQVE 158 >UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyledons|Rep: T2K10.1 protein - Arabidopsis thaliana (Mouse-ear cress) Length = 176 Score = 127 bits (306), Expect = 2e-28 Identities = 69/162 (42%), Positives = 102/162 (62%), Gaps = 10/162 (6%) Frame = +2 Query: 95 NTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIA 274 +++P++ GT E + E V AI+ GYRH DT+ YQ EE +G+ +AEA++ Sbjct: 19 HSMPVLGFGTAASPLPEPTMLKET---VIEAIKLGYRHFDTSPRYQTEEPIGEALAEAVS 75 Query: 275 NGLV-TREELFVTTKLW-NDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP---- 436 GLV +R E FVTTKLW D H VVPA++ SLK L LDY+DLY+IH+P+++KP Sbjct: 76 LGLVRSRSEFFVTTKLWCADAHG-GLVVPAIKRSLKNLKLDYLDLYIIHWPVSSKPGKYK 134 Query: 437 ----DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 550 +D +D+ W M++ ++LGLA+ IGVSNF+ ++ Sbjct: 135 FPIDEDDFMPMDFEVVWSEMEECQRLGLAKCIGVSNFSCKKL 176 >UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 316 Score = 127 bits (306), Expect = 2e-28 Identities = 71/186 (38%), Positives = 107/186 (57%), Gaps = 11/186 (5%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 ++LN G +IP + LGT + EV A+ A+ AGYRHID A VYQ++++VG+ Sbjct: 5 LKLNSGYSIPAIGLGTWQSKP------GEVAAAIKTAVAAGYRHIDCAHVYQNQKEVGEA 58 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP--IAT 430 + E + G V REELF+T+K+WN H+ + + L L L Y+DL LIH+P A Sbjct: 59 LKEILDEGKVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHWPQGYAE 118 Query: 431 KPDDSP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRP 583 + P ++DYLETW+ + A++ G RSIG+SNF +QI R+ + ++P Sbjct: 119 GAELFPAGENGKMRYSDVDYLETWKAFEAAQKAGKCRSIGLSNFTHSQIQRVWDAAEVKP 178 Query: 584 GXNQIE 601 Q+E Sbjct: 179 ACLQVE 184 >UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=3; Trichomonas vaginalis G3|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 309 Score = 127 bits (306), Expect = 2e-28 Identities = 71/175 (40%), Positives = 111/175 (63%), Gaps = 16/175 (9%) Frame = +2 Query: 125 GRGTAKESDSIDEVRQAVYWAIE-AGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREEL 301 G GT D ++ AV+ AIE +GYRH+D AA Y+++E +G+ ++E A G V REE+ Sbjct: 8 GLGTFLAEDPA-ALKAAVHSAIEDSGYRHVDCAAYYKNQEIIGEALSEIFAKGQVKREEV 66 Query: 302 FVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA--TKPDDS---------- 445 ++T+K+WN KH D +V ++++LK+L L+Y+DL L+H+ A ++ DD Sbjct: 67 WITSKVWNTKHRPDLLVKDVKKTLKELKLEYLDLVLVHWACAFQSREDDEYLPRDETGKI 126 Query: 446 -PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS--YIRPGXNQIE 601 +NID LETW+ M++ LGLA+ IGVSNF+ Q+ R+ + I+P NQ+E Sbjct: 127 ITENIDILETWKAMEECYNLGLAKHIGVSNFSIEQLERMRYDPGVKIQPYCNQVE 181 >UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH - Aspergillus niger Length = 345 Score = 127 bits (306), Expect = 2e-28 Identities = 80/187 (42%), Positives = 108/187 (57%), Gaps = 13/187 (6%) Frame = +2 Query: 80 QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259 +LN G +P V LGT + DEVR AV A++ GYRHID AAVY +E++VG G+ Sbjct: 8 KLNTGYDMPAVGLGTWQSKK------DEVRDAVIAALKCGYRHIDAAAVYGNEQEVGDGM 61 Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 439 +G V REE+F+T+KLWN H + V A+ +SL L DY+DLYLIH+P+A + Sbjct: 62 R---LSG-VPREEIFLTSKLWNTHHHPENVEEAVDKSLADLQTDYLDLYLIHWPVAFRYS 117 Query: 440 DS---PDN-----IDYL-----ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 580 + P N ID + +TW M+ + G RSIGVSNF +I L+ + I Sbjct: 118 TTTIQPVNEQTGLIDVVDVPIKDTWAAMEKLVEKGKVRSIGVSNFTREKIEELLKTAKIT 177 Query: 581 PGXNQIE 601 P NQIE Sbjct: 178 PAVNQIE 184 >UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto reductase family - Thermotoga maritima Length = 286 Score = 126 bits (305), Expect = 3e-28 Identities = 76/180 (42%), Positives = 104/180 (57%) Frame = +2 Query: 62 VQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEE 241 +Q P + LN+G +PI+ G + ++++ + VY AI+ GYR IDTAA Y +EE Sbjct: 1 MQVPKVTLNNGVEMPILGYGVFQIPPEKTE------ECVYEAIKVGYRLIDTAASYMNEE 54 Query: 242 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 421 VG+ I AI G+V REELFVTTKLW + A ++SLKKL L+YIDLYLIH P Sbjct: 55 GVGRAIKRAIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQP 114 Query: 422 IATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 D W+ M++ + GL R+IGVSNF ++ L+ + I P NQIE Sbjct: 115 FG----------DVHCAWKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVHHEIVPAVNQIE 164 >UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; Actinobacteria (class)|Rep: 2,5-didehydrogluconate reductase - Arthrobacter sp. (strain FB24) Length = 276 Score = 126 bits (304), Expect = 4e-28 Identities = 76/178 (42%), Positives = 105/178 (58%) Frame = +2 Query: 68 APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247 +P I+LNDG+ IP + LGT D +V AV A+E GYRHIDTA Y +E+ V Sbjct: 4 SPVIELNDGHRIPQIGLGTW-----PLDD-HQVAAAVVNAVEGGYRHIDTAVKYGNEKGV 57 Query: 248 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427 G GI ++GL R ELF+TTKL + +D+ V L SLK+LGLDY+DL LIH+P+ Sbjct: 58 GNGIR---SSGL-DRSELFITTKLDGEFQGQDRAVAGLDGSLKRLGLDYVDLLLIHWPL- 112 Query: 428 TKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 P +++ TW+ + + G RSIGVSNF + RL++ + P NQI+ Sbjct: 113 ------PRRDEFISTWKTFERLQADGKVRSIGVSNFKPAHLERLMAACDVVPAVNQIQ 164 >UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep: Aldose reductase - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 312 Score = 126 bits (303), Expect = 5e-28 Identities = 75/187 (40%), Positives = 111/187 (59%), Gaps = 14/187 (7%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262 LN G IP LGT +G +++AV AI++GYR ID A VY +EE+VGQGI Sbjct: 8 LNTGAKIPAFGLGTWQGDK------GVIKEAVLTAIKSGYRLIDGAYVYGNEEEVGQGIR 61 Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 436 EAI++G+V RE+LFV +K W R ++ L +SLK LGLDY+DLYL+H+PI P Sbjct: 62 EAISSGIVKREDLFVVSKCWATYTTRCEL--GLDQSLKLLGLDYVDLYLVHWPILMNPEG 119 Query: 437 ---------DDSPDNI---DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 580 D S D I ++++TW+ M+ G +++GVSN++ + +L+ ++ Sbjct: 120 NDEKFPKHADGSRDIIHTHNHVDTWKLMEKLPATGKTKAVGVSNYSKAWLEQLLPHATTV 179 Query: 581 PGXNQIE 601 P NQ+E Sbjct: 180 PAVNQVE 186 >UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 337 Score = 125 bits (302), Expect = 7e-28 Identities = 78/188 (41%), Positives = 111/188 (59%), Gaps = 15/188 (7%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAI-EAGYRHIDTAAVYQDEEQVGQGI 259 LN+G TIP + LGT + T +EV AV A+ E GYRHIDTA Y++E+ VG GI Sbjct: 36 LNNGKTIPAIGLGTWKSTT------EEVAGAVECALTEGGYRHIDTAFNYRNEDAVGLGI 89 Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 439 A+ G V RE++FVTTK+W H D+V L SL++LGLDY+D+ LIH+P+ P+ Sbjct: 90 KRAMEKG-VKREDIFVTTKIWVTYH--DRVEENLDMSLERLGLDYVDMLLIHWPVPLNPN 146 Query: 440 DS-------PD---NID----YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 577 + PD +ID +TW+ M+ + G +SIGVSNF+ + L+ + + Sbjct: 147 GNDPVYPLRPDGSRDIDESGSQPKTWKQMEAVLKTGKTKSIGVSNFSIPYLEELLKEAEV 206 Query: 578 RPGXNQIE 601 P NQ+E Sbjct: 207 VPAVNQVE 214 >UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomycetales|Rep: Putative oxidoreductase - Streptomyces coelicolor Length = 277 Score = 125 bits (301), Expect = 9e-28 Identities = 77/182 (42%), Positives = 107/182 (58%) Frame = +2 Query: 56 MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235 M+ + P I LN+G +P + G G + D D+ + AV A+EAGYR IDTAA+Y + Sbjct: 1 MSSKVPPIILNNGVEMPQL----GFGVWQVPD--DDAQTAVALALEAGYRSIDTAAIYGN 54 Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415 EE G+ IA A+GL RE+LFVTTKLWN D + A S+ KLGL+Y+DLYLIH Sbjct: 55 EEGTGRAIA---ASGLA-REDLFVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYLDLYLIH 110 Query: 416 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQ 595 +P+ K Y++T++ + G R+IGVSNF + RL + + + P NQ Sbjct: 111 WPMPAKE-------RYVDTYKAFEKLLADGRVRAIGVSNFLPEHLERLTAETSVIPAVNQ 163 Query: 596 IE 601 IE Sbjct: 164 IE 165 >UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep: Oxidoreductase - Lactobacillus acidophilus Length = 285 Score = 125 bits (301), Expect = 9e-28 Identities = 68/172 (39%), Positives = 102/172 (59%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262 LN+G IPI+ GT ++ + ++V A+ GYRHIDTA+ Y +E+ VG+ I Sbjct: 12 LNNGVKIPIIGFGTW-----QTPDGEVAEESVLAALNCGYRHIDTASAYGNEDSVGRAIQ 66 Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 442 ++ N R ELF+TTKLWN H ++ A+ +SL L LDY+D+YLIH+P + D Sbjct: 67 KSGIN----RHELFITTKLWNSDHGYEKTKKAIDQSLLDLKLDYLDMYLIHWPNPSSMRD 122 Query: 443 SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598 I+ E+W+ M++A + G R+IGVSNF + L+ + I+P NQI Sbjct: 123 HWAEIN-AESWRAMEEAVRAGKIRAIGVSNFRKHHLDALMETAEIKPVVNQI 173 >UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=2; Tetrahymena thermophila SB210|Rep: Oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 332 Score = 124 bits (300), Expect = 1e-27 Identities = 64/175 (36%), Positives = 109/175 (62%), Gaps = 1/175 (0%) Frame = +2 Query: 80 QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259 +LN+G +P+V LGT +KE E+ + A++AGYRHIDTA YQ+E +G+ + Sbjct: 9 KLNNGQIMPLVGLGTYLLNSKE-----EMTNLLRTALDAGYRHIDTAVNYQNEAMIGESL 63 Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA-TKP 436 G +R++LF+ +K++ +K ++ ++++SLK+L LDY+DLY +HFP+ Sbjct: 64 KTIFKEGKYSRKDLFIVSKVFPNKGI--NMLESVKKSLKELQLDYVDLYYLHFPLGFLSE 121 Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 + ++ W +++A +LGLA+SIGVSNFN + L+S + ++P NQ+E Sbjct: 122 KEEFVHLPVHVAWAQLEEAHRLGLAKSIGVSNFNVMALADLLSYAKVKPVSNQVE 176 >UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Dikarya|Rep: Aldo-keto reductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 353 Score = 124 bits (300), Expect = 1e-27 Identities = 77/205 (37%), Positives = 116/205 (56%), Gaps = 14/205 (6%) Frame = +2 Query: 29 TLTCLLNAAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRH 208 T+ + N+ + +LN G +IP + LGT + A EVRQAV A++AGYRH Sbjct: 23 TILPIFNSLIMSAPTSFKLNTGASIPAIGLGTWQAKA------GEVRQAVAHALKAGYRH 76 Query: 209 IDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGL 388 ID A YQ+E++VG GI + +G V R E+F+T+K+W+ H D+V L +LK L Sbjct: 77 IDGALCYQNEDEVGLGIKD---SG-VPRSEIFLTSKVWSSYH--DRVEECLDTTLKSLQT 130 Query: 389 DYIDLYLIHFPIATKPDDS-------PD---NIDY----LETWQGMQDARQLGLARSIGV 526 DY+DLYLIH+P+ P+ + PD N+D+ +TW M+D + G A++IG+ Sbjct: 131 DYLDLYLIHWPVRLAPNGTHPLFPVKPDGSRNLDWDWDQAKTWAQMEDVLKKGKAKAIGL 190 Query: 527 SNFNATQITRLVSNSYIRPGXNQIE 601 SN I ++ + P NQ+E Sbjct: 191 SNAGIPIIEHIIKTGKVTPAVNQVE 215 >UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose reductase - Hordeum vulgare (Barley) Length = 320 Score = 124 bits (300), Expect = 1e-27 Identities = 73/180 (40%), Positives = 112/180 (62%), Gaps = 7/180 (3%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262 L G+ +P V LGT R SD+ VR A+ EAGYRH+DTAA Y E++VG+G+ Sbjct: 18 LKSGHAMPAVGLGTWRAG---SDTAHSVRTAI---TEAGYRHVDTAAEYGVEKEVGKGLK 71 Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK--- 433 A+ G + R++LFVT+K+W A ++V PAL+ +LK L LDYIDLY IH+P K Sbjct: 72 AAMEAG-IDRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLKDGA 130 Query: 434 --PDDSPDNIDY-LE-TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 P ++ + +++ +E W+ M++ + GL + IGV N+ T++ RL+ ++ I P Q+E Sbjct: 131 HMPPEAGEVLEFDMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAKIPPAVCQME 190 >UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to GA15457-PA - Nasonia vitripennis Length = 388 Score = 124 bits (299), Expect = 2e-27 Identities = 76/205 (37%), Positives = 118/205 (57%), Gaps = 12/205 (5%) Frame = +2 Query: 23 IITLTCLLNAAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGY 202 ++ L +L A AV+ ++L+ G+ IP V LGT T K +DE+ A+ A+E GY Sbjct: 10 LVVLAVVLPGAQAVEK--LKLSSGHEIPAVGLGTS--TIK----LDEMDNAISSALENGY 61 Query: 203 RHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKL 382 RHIDTA Y +E +G+ + + G RE++F+T+KL + + V L+ SLK L Sbjct: 62 RHIDTAFSYDNEAAIGKILKKWFDKG-GKREDIFITSKLPSQGNRPQSVETYLKRSLKDL 120 Query: 383 GLDYIDLYLIHFPIATKP------------DDSPDNIDYLETWQGMQDARQLGLARSIGV 526 GLDY+D+YLIH P A K +D D++D+ W+ M+ + G A+SIG+ Sbjct: 121 GLDYVDMYLIHTPFAVKEGENLSSKQDKDGNDLFDDVDHKALWKAMERQVKEGRAKSIGL 180 Query: 527 SNFNATQITRLVSNSYIRPGXNQIE 601 SNFN +Q+ + +N+ I+P Q+E Sbjct: 181 SNFNQSQVLNIYNNAEIKPSNLQVE 205 >UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5; Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 321 Score = 124 bits (299), Expect = 2e-27 Identities = 75/193 (38%), Positives = 101/193 (52%), Gaps = 16/193 (8%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P +LN G +P+V G + D++ Y AI+AGYR D A Y +E + G Sbjct: 4 PSTKLNSGYDMPLVGFGLWK--VNNETCADQI----YHAIKAGYRLFDGACDYGNEVEAG 57 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430 +G+A AI G+V RE+LF+ +KLWN H D+V P ++ L GLDY DL+++HFPIA Sbjct: 58 KGVARAIQEGIVKREDLFIVSKLWNSFHDGDRVEPICRKQLADWGLDYFDLFIVHFPIAL 117 Query: 431 KPDDSP----------------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 562 K D N ETW M+ LARSIGVSNF+A + L+ Sbjct: 118 KYVDPAVRYPPGWLSENNKLEFSNASIQETWTAMESLVDKKLARSIGVSNFSAQLLMDLL 177 Query: 563 SNSYIRPGXNQIE 601 + IRP QIE Sbjct: 178 RYARIRPATLQIE 190 >UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; Bacteria|Rep: 2,5-didehydrogluconate reductase - Exiguobacterium sibiricum 255-15 Length = 274 Score = 124 bits (298), Expect = 2e-27 Identities = 67/175 (38%), Positives = 107/175 (61%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 + LN+G +P + G G K + EV +AV A+ GYR IDTA +Y++E VG+ Sbjct: 4 VTLNNGLVMPQL----GYGVFKVPEQ--EVYEAVREALRVGYRSIDTAMIYENEAGVGR- 56 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 A+ + + RE++F+TTK+WN ++ + A + SL+KLG+DY+DLYLIH+P+ Sbjct: 57 ---ALKDSGIPREDIFLTTKVWNKDQGYERTLAAFETSLQKLGVDYVDLYLIHWPM---- 109 Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 PD Y++TW+ ++ + G A++IGVSNF+ +TR++ + P NQIE Sbjct: 110 ---PDEDLYMDTWRALEQLYRDGKAKAIGVSNFHIPHLTRVLEEGTVVPAVNQIE 161 >UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG2767-PA - Drosophila melanogaster (Fruit fly) Length = 329 Score = 124 bits (298), Expect = 2e-27 Identities = 71/193 (36%), Positives = 107/193 (55%), Gaps = 13/193 (6%) Frame = +2 Query: 62 VQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEE 241 V + N+G +P++ +GT + S +E+ A+ A+EAGYRHIDTA VY +E+ Sbjct: 2 VNTKFLTFNNGEKMPVIGIGTWQA------SDEEIETAIDAALEAGYRHIDTAPVYGNEK 55 Query: 242 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 421 +G+ + + G V REELF+ TK+ + +V P +++SL+ L LDY+DLYL+H P Sbjct: 56 AIGRVLKRWLDAGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTP 115 Query: 422 IATK-PDDSPDNID------------YLETWQGMQDARQLGLARSIGVSNFNATQITRLV 562 +D +D + W M+ + GL +SIGVSNF+ Q+ RL+ Sbjct: 116 FTININEDGSFKLDKEGLMEVDVTTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLL 175 Query: 563 SNSYIRPGXNQIE 601 N IRP NQIE Sbjct: 176 KNCKIRPANNQIE 188 >UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep: Oxidoreductase - Xanthomonas campestris pv. campestris (strain 8004) Length = 267 Score = 123 bits (297), Expect = 3e-27 Identities = 74/146 (50%), Positives = 94/146 (64%) Frame = +2 Query: 98 TIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIAN 277 T+P LGT R K+ ID VR A + GYR IDTA +Y +E QVGQ IA+A Sbjct: 2 TVPAFGLGTFR--LKDQVVIDSVRNA----LALGYRAIDTAQIYDNEAQVGQAIADA--- 52 Query: 278 GLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNI 457 G V R++LFVTTK+W D+ +RD + P+LQESL+KLG DY+DL LIH+P P D Sbjct: 53 G-VPRDQLFVTTKIWVDRFSRDTLQPSLQESLRKLGTDYVDLTLIHWP---SPKDQVPMR 108 Query: 458 DYLETWQGMQDARQLGLARSIGVSNF 535 +YLE + DA+ GL R+IGVSNF Sbjct: 109 EYLE---ALADAKAQGLTRAIGVSNF 131 >UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae str. PEST Length = 310 Score = 123 bits (296), Expect = 4e-27 Identities = 73/188 (38%), Positives = 106/188 (56%), Gaps = 12/188 (6%) Frame = +2 Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253 CI L+D ++I + +G G + +D ++A+ AI+ GYR DTA Y +E VG+ Sbjct: 6 CINLSDQHSIALPTIGLGTYSILGADG----KEAIRTAIDVGYRMFDTAVAYGNEAIVGE 61 Query: 254 GIAEAIAN-GLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA- 427 I E I +TR++ F+ +KL H +D V + +L +LG+DY+DLYL+H P+A Sbjct: 62 AIREKIRECNNLTRDDFFIISKLSGSYHRQDLVEKCCRMTLDRLGMDYVDLYLMHTPVAL 121 Query: 428 ----------TKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 577 TK + D+I E W G++ Q GL RSIGVSNFN QI L+S++ I Sbjct: 122 QSEKKCARNGTKLNAIDDSIAPTEAWIGLEQCYQEGLCRSIGVSNFNEHQINALLSDASI 181 Query: 578 RPGXNQIE 601 P NQIE Sbjct: 182 VPAVNQIE 189 >UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; Bacteria|Rep: 2,5-didehydrogluconate reductase - Opitutaceae bacterium TAV2 Length = 334 Score = 122 bits (294), Expect = 7e-27 Identities = 74/177 (41%), Positives = 103/177 (58%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P + L+DG +IP + LG + D QA A AGYR IDTA +Y +EE VG Sbjct: 60 PTLPLSDGTSIPQLGLGVWQ---MPDDGAGVPIQA---AFNAGYRAIDTAPIYGNEEGVG 113 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430 + I A+GL R+EL++TTK+WN D + A++ESL +L L+Y+DLYLIH+P+ Sbjct: 114 RAIR---ASGL-PRKELYITTKVWNSAQGYDSTLRAVRESLGRLQLEYVDLYLIHWPV-- 167 Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 P Y++TW+ + + GLARSIGVSNF + RL + I P NQ+E Sbjct: 168 -----PKIDRYVDTWKALAKIKADGLARSIGVSNFTPVYLQRLFDETGIVPVVNQVE 219 >UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1; Arabidopsis thaliana|Rep: Uncharacterized protein At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress) Length = 283 Score = 122 bits (294), Expect = 7e-27 Identities = 71/188 (37%), Positives = 103/188 (54%), Gaps = 6/188 (3%) Frame = +2 Query: 56 MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235 MA +LN G P V LGT + S V AV A++ GYRHID A +Y + Sbjct: 1 MANAITFFKLNTGAKFPSVGLGTWQA------SPGLVGDAVAAAVKIGYRHIDCAQIYGN 54 Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415 E+++G + + + +V RE+LF+T+KLW H V AL +LK L L+Y+DLYLIH Sbjct: 55 EKEIGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIH 114 Query: 416 FPIATKPDD---SPDN---IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 577 +P K P+N +D TW+ M+ G AR+IGVSNF+ ++ L+ + + Sbjct: 115 WPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARV 174 Query: 578 RPGXNQIE 601 P NQ+E Sbjct: 175 PPAVNQVE 182 >UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis thaliana (Mouse-ear cress) Length = 315 Score = 122 bits (294), Expect = 7e-27 Identities = 71/188 (37%), Positives = 103/188 (54%), Gaps = 6/188 (3%) Frame = +2 Query: 56 MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235 MA +LN G P V LGT + S V AV A++ GYRHID A +Y + Sbjct: 1 MANAITFFKLNTGAKFPSVGLGTWQA------SPGLVGDAVAAAVKIGYRHIDCAQIYGN 54 Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415 E+++G + + + +V RE+LF+T+KLW H V AL +LK L L+Y+DLYLIH Sbjct: 55 EKEIGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIH 114 Query: 416 FPIATKPDD---SPDN---IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 577 +P K P+N +D TW+ M+ G AR+IGVSNF+ ++ L+ + + Sbjct: 115 WPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARV 174 Query: 578 RPGXNQIE 601 P NQ+E Sbjct: 175 PPAVNQVE 182 >UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Lin2739 protein - Listeria innocua Length = 283 Score = 121 bits (292), Expect = 1e-26 Identities = 75/175 (42%), Positives = 101/175 (57%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 ++LN+G +PI+ GT + T E QAV AI AGYRHIDTA Y +EE VG+G Sbjct: 4 VKLNNGIEVPILGFGTYQIT-----DAGEAEQAVKEAIAAGYRHIDTAQSYMNEEAVGRG 58 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 IA A+G V R+ELF+TTK+W + + V+ + SLK+LGLDYIDL LIH P Sbjct: 59 IA---ASG-VDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYIDLLLIHQPYN--- 111 Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 D W M++ + G ++IGVSNF ++ L + + I P NQIE Sbjct: 112 -------DVYGAWMAMEELQAQGKIKAIGVSNFGVDRVVDLAAFNDITPQVNQIE 159 >UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2; Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid reductase - Tropheryma whipplei (strain Twist) (Whipple's bacillus) Length = 283 Score = 121 bits (292), Expect = 1e-26 Identities = 72/177 (40%), Positives = 101/177 (57%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P + L DG +IP LGT E+ S+ V AIE GYRHIDTA++Y +E +VG Sbjct: 10 PSVLLGDGVSIPQFGLGTYELPPNEASSV------VQSAIELGYRHIDTASLYANEREVG 63 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430 + AIA+ + REE FVTTKLWN + + A + SL L LDY+DLYLIH+P Sbjct: 64 R----AIASSGIKREEFFVTTKLWNSDQPKPR--EAFERSLDLLSLDYVDLYLIHWP--- 114 Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 P + Y+ W+ + + ++ G A+S+GVSNF + I ++ + P NQIE Sbjct: 115 ----CPPSELYINVWEVLLELKESGRAKSVGVSNFLSEHIDKIKEAGFPLPSVNQIE 167 >UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas putida Length = 296 Score = 121 bits (292), Expect = 1e-26 Identities = 75/182 (41%), Positives = 109/182 (59%) Frame = +2 Query: 56 MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235 MA ++P I LN+G +P + LG +A+E+ S A+ AI +GYR IDTA Y + Sbjct: 1 MAGKSPLINLNNGVKMPALGLGVFAASAEETAS------AIASAISSGYRLIDTARSYNN 54 Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415 E QVG+GI N V R E+FVTTKL+N + ++ + A ESL +LGLDY+DLYL+H Sbjct: 55 EAQVGEGIR----NSGVDRAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLH 110 Query: 416 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQ 595 +P TK ++ +++W+ + G AR+IGV NF Q+ L++ S + P NQ Sbjct: 111 WP--TKDWNAT-----IQSWKAAEKILGDGRARAIGVCNFLEDQLDELIAASDVVPAVNQ 163 Query: 596 IE 601 IE Sbjct: 164 IE 165 >UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; Actinomycetales|Rep: 2,5-didehydrogluconate reductase - Kineococcus radiotolerans SRS30216 Length = 289 Score = 120 bits (289), Expect = 3e-26 Identities = 77/181 (42%), Positives = 106/181 (58%) Frame = +2 Query: 59 AVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDE 238 A+ P I LNDG IP LG G + D+ QAV A++ GYRHIDTA +Y +E Sbjct: 9 AMTVPTILLNDGREIP--QLGFGVFQIEPGDTA----QAVKTALDLGYRHIDTAQMYGNE 62 Query: 239 EQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 418 +V QGIA++ G V R+E++VT+KL N H D A+ +S++KL IDLYLIH+ Sbjct: 63 AEVAQGIADS---G-VPRDEIWVTSKLNNGFHEPDAARKAVDDSVEKLR-GPIDLYLIHW 117 Query: 419 PIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598 P+ T D++ TW+ +++AR G RSIGVSNF + RL + + P NQI Sbjct: 118 PLPTLYGG-----DFVSTWKVLEEARAAGKLRSIGVSNFQVNHLQRLAQEATVVPAVNQI 172 Query: 599 E 601 E Sbjct: 173 E 173 >UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 protein; n=6; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to LOC553452 protein - Strongylocentrotus purpuratus Length = 321 Score = 120 bits (288), Expect = 4e-26 Identities = 72/182 (39%), Positives = 102/182 (56%), Gaps = 13/182 (7%) Frame = +2 Query: 56 MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235 MA I L G +P++ GT + +EV + + AI+ GYRHID A++Y + Sbjct: 1 MASSNTHIVLPGGRKLPLLGFGTWQIKP------EEVGRVIETAIDCGYRHIDEASLYGN 54 Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLW-NDKHARDQVVPALQESLKKLGLDYIDLYLI 412 E+ VG GI I +G + RE+LFVT+KLW D H +V P+ ++SL LGL Y+DL+LI Sbjct: 55 EKGVGDGIKAKIDDGTIKREDLFVTSKLWVTDSHP-SRVEPSCRQSLSDLGLAYLDLFLI 113 Query: 413 HFPIATKPDDSP------------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITR 556 H P + P D IDY++TW+ M+ GL R+IGVSNF QI R Sbjct: 114 HCPTSAVGGKGPFPMDDNGLFIGDDTIDYVDTWRIMESLVDKGLVRAIGVSNFTVAQIQR 173 Query: 557 LV 562 ++ Sbjct: 174 VL 175 >UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lmo2592 protein - Listeria monocytogenes Length = 283 Score = 119 bits (287), Expect = 5e-26 Identities = 74/175 (42%), Positives = 105/175 (60%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 ++LN+G +PI+ G GT + +D+ E AV AI+AGYRHIDTA Y +EE VG+G Sbjct: 4 VKLNNGVEVPIL----GFGTYQITDAA-EAEHAVKDAIKAGYRHIDTAQSYMNEEAVGRG 58 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 IA A+G V R+ELF+TTK+W + + V+ + SLK+LGLDY+DL LIH P Sbjct: 59 IA---ASG-VDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYVDLLLIHQPFN--- 111 Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 D W M++ + G R+IGVSNF+ ++ L + + + P NQIE Sbjct: 112 -------DVYGAWIAMEELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQIE 159 >UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Escherichia coli (strain UTI89 / UPEC) Length = 294 Score = 119 bits (287), Expect = 5e-26 Identities = 66/160 (41%), Positives = 93/160 (58%), Gaps = 1/160 (0%) Frame = +2 Query: 125 GRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 304 G G + +D D +Q+V AI GYR IDTAAVY +E+ VG+ + EAI+ GL TREELF Sbjct: 21 GFGVFQVTDK-DVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGEAVREAISEGLCTREELF 79 Query: 305 VTTKLW-NDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQG 481 +T+KLW D +D ++ SLKK GL+Y DLYL+H + DY W+ Sbjct: 80 ITSKLWVQDMLNQDIAAAGIEASLKKSGLEYFDLYLLHQAMR----------DYFSAWRA 129 Query: 482 MQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 ++DA + G ++IGVSNF + ++P NQ+E Sbjct: 130 LEDAYEEGKLKAIGVSNFYPHVLANFCETVRVKPMVNQVE 169 >UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB49|Rep: ARA1 - unidentified eubacterium SCB49 Length = 280 Score = 119 bits (287), Expect = 5e-26 Identities = 64/174 (36%), Positives = 106/174 (60%) Frame = +2 Query: 80 QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259 +LN+ IP + GT + T +I+ ++ A I+AGY+HID AA+Y++E+ VG GI Sbjct: 6 KLNNNINIPAIGFGTWQ-TPDGQTAINAIKTA----IDAGYKHIDAAAIYKNEKGVGLGI 60 Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 439 EA + R++LFVT+K+WN++ + + A ++ L LDY+DLYLIH+P A Sbjct: 61 KEAN----IDRKDLFVTSKVWNEQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAAHQF 116 Query: 440 DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 ++ ++ +TW M+ + G +++GVSNF +T L+ ++ I+P NQIE Sbjct: 117 ENWKQLNN-DTWSAMEKLYKDGKIKALGVSNFMEHHLTPLLQHATIKPTVNQIE 169 >UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 275 Score = 119 bits (287), Expect = 5e-26 Identities = 71/173 (41%), Positives = 99/173 (57%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262 L+DG IP LG K + +QAV WA+E GYR IDTAA Y +E++VG Sbjct: 9 LSDGYKIPRFGLGLYDLDEKHT------KQAVLWALENGYRMIDTAASYNNEKRVG---- 58 Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 442 EA+ V R E+++ TK+++ H ++ + A SL LG+DY+DLYLIHFP+ Sbjct: 59 EALRESAVPRSEVYLVTKVYHTDHGYEKTMKAYDRSLSALGVDYVDLYLIHFPV------ 112 Query: 443 SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 P + + +W+ M + + GL RSIGVSNFN + L +S I P NQIE Sbjct: 113 -PAGV--VGSWEAMAELQGKGLTRSIGVSNFNIHHLEALQKHSVIPPVVNQIE 162 >UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 289 Score = 119 bits (286), Expect = 6e-26 Identities = 69/181 (38%), Positives = 101/181 (55%) Frame = +2 Query: 59 AVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDE 238 A+ P + L++G IPI+ LGT +++ +Y E G RHIDTA Y E Sbjct: 10 ALSCPAVPLHNGLNIPILGLGTSHYGGYSHEAV------LYALQECGIRHIDTAKRYGCE 63 Query: 239 EQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 418 E +G+ + E+ G V REEL+VTTKLW + A ++S +LG+DY+DLYL+H+ Sbjct: 64 EALGKAVTES---G-VQREELWVTTKLWPGDYGYQSTKQACRDSRARLGVDYLDLYLMHW 119 Query: 419 PIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598 P + P S + LETW+ +++ GL R+IGVSNF + L + I P NQ+ Sbjct: 120 PDSMVPGRSSQEV-RLETWRALEELYDEGLCRAIGVSNFLIPHLNELKDSGGIVPHVNQV 178 Query: 599 E 601 E Sbjct: 179 E 179 >UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia sp. (strain CCS1) Length = 276 Score = 119 bits (286), Expect = 6e-26 Identities = 71/177 (40%), Positives = 102/177 (57%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P I+ +DG IP V G + D + V AIE GYR ID A +Y +E +G Sbjct: 5 PVIKFHDGAQIPQVGFGIWQVPQ------DIAGETVRSAIEIGYRMIDGAYLYMNEAGLG 58 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430 +G+ A+GL R+E+FVTTK+WN++ + +++ SLK +G++ +DL LIH+P+ Sbjct: 59 EGLR---ASGL-PRDEVFVTTKVWNNEQGAAKARASVERSLKTIGVEQLDLVLIHWPV-- 112 Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 P YLETW+ QD R GL RSIG SNFNA + R+++ + P NQIE Sbjct: 113 -----PSQDLYLETWKAFQDMRDEGLMRSIGTSNFNADHLERIIAETGEAPVLNQIE 164 >UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 339 Score = 119 bits (286), Expect = 6e-26 Identities = 65/194 (33%), Positives = 110/194 (56%), Gaps = 16/194 (8%) Frame = +2 Query: 68 APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247 A + LN G +P++ GT + ++ + + VR A +EAGYRHID+A ++++E+V Sbjct: 4 ADTVTLNSGYEMPVIGYGTWQ--LPKNLAAERVRDA----LEAGYRHIDSALSFKNQEEV 57 Query: 248 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427 GI + V REELF+++K+WN H+R++ + + E L+ Y+DL +IH+P Sbjct: 58 AAGIKDWCKIRKVRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIHWPFG 117 Query: 428 TKPDDSP----------------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRL 559 D+ P ++DYLETW+ ++DA + G RSIG++NFN Q+ ++ Sbjct: 118 WAEDEPPGERGLWPRGANGKMRYSDVDYLETWKALEDAHRSGKIRSIGLANFNIGQVEQV 177 Query: 560 VSNSYIRPGXNQIE 601 + I+P Q+E Sbjct: 178 WTKGLIKPAVLQVE 191 >UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: Aldehyde reductase - Acidobacteria bacterium (strain Ellin345) Length = 313 Score = 118 bits (285), Expect = 8e-26 Identities = 66/177 (37%), Positives = 97/177 (54%), Gaps = 12/177 (6%) Frame = +2 Query: 107 IVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLV 286 I ALG G A + +I R A + AG+RH D A Y++E +VG+ + A G + Sbjct: 20 IPALGFGTLIADPALTITATRDA----LAAGFRHFDCAERYRNEREVGEALRAGRAAGNI 75 Query: 287 TREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPD----- 451 REE+FVTTKLWN H ++V PA + SL +LGLDY+DLYLIH P A +P D D Sbjct: 76 AREEIFVTTKLWNTNHRPERVEPAFEASLDRLGLDYLDLYLIHTPFAFQPGDEQDPRDQN 135 Query: 452 -------NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 + ETW +++ G R+IG+S+ + ++ + + I+P Q+E Sbjct: 136 GSVIYDEGVTLRETWSALENLVDRGRCRAIGLSDISMDRLAPIYEAARIKPAVVQVE 192 >UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomycetaceae|Rep: Glycerol dehydrogenase - Zygosaccharomyces rouxii (Candida mogii) Length = 310 Score = 118 bits (285), Expect = 8e-26 Identities = 78/195 (40%), Positives = 114/195 (58%), Gaps = 20/195 (10%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 ++LN G TIP V LGT R +KE++ +AV A++AGYRHID AAVY +E +VG+ Sbjct: 11 LKLNTGQTIPQVGLGTWR--SKENEGY----KAVIEALKAGYRHIDGAAVYGNEGEVGK- 63 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI---- 424 AI + V R E+F+TTKLW Q AL +SL++LGLDY+ LYL+H+P+ Sbjct: 64 ---AIQDSGVPRNEIFLTTKLWCTHQRNPQ--EALDQSLQRLGLDYVGLYLVHWPVPLRT 118 Query: 425 -----------ATKPDDSPD---NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 562 A KPD S D ++++TW+ MQ + G ++IGVSNF+ + L+ Sbjct: 119 ENIKDGNLFQFAEKPDGSKDVDLEWNFIKTWELMQKLLESGKTKAIGVSNFSVNNLKDLL 178 Query: 563 S--NSYIRPGXNQIE 601 + + + P NQ+E Sbjct: 179 AAPTTKVTPAVNQVE 193 >UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto reductase family - Enterococcus faecalis (Streptococcus faecalis) Length = 279 Score = 118 bits (284), Expect = 1e-25 Identities = 69/178 (38%), Positives = 99/178 (55%) Frame = +2 Query: 68 APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247 A + LN+G IP G G G + D +E + V I GYR IDTA +Y +E Sbjct: 6 ADTVTLNNGTKIP----GMGLGVFQIPD--EETAKVVEEGIINGYRLIDTAQIYGNESGT 59 Query: 248 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427 G GI +A + RE+LFVT+K+WN + D+ + A +SL++LGLDY+DLYLIH+ Sbjct: 60 GAGIKAGLAATGLNREDLFVTSKVWNAHISYDETIQAFNDSLERLGLDYLDLYLIHW--- 116 Query: 428 TKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 P N Y E+WQ ++ G ++IGVSNF + L+S + + P NQ+E Sbjct: 117 ------PGNNSYKESWQALETLYAEGKVKAIGVSNFQVHHLEDLLSYAKVVPVINQVE 168 >UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: Benzil reductase - Bacillus subtilis Length = 276 Score = 118 bits (284), Expect = 1e-25 Identities = 68/175 (38%), Positives = 108/175 (61%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 ++L++G +P LG + ++ +E ++V AI+ GYR IDTAA+Y++EE VG G Sbjct: 9 VKLHNGVEMPWFGLGVFK-----VENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIG 63 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 I E+ G V REELF+T+K+WN+ + + A ++SL++L LDY+DLYLIH+P K Sbjct: 64 IKES---G-VAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWPGKDK- 118 Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 Y +TW+ ++ + G R+IGVSNF + L+ ++ I+P NQ+E Sbjct: 119 --------YKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQVE 165 >UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; Erythrobacter sp. SD-21|Rep: Putative oxidoreductase protein - Erythrobacter sp. SD-21 Length = 272 Score = 118 bits (283), Expect = 1e-25 Identities = 65/177 (36%), Positives = 102/177 (57%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P + LNDG IP LG G +E D+ QAV AI+ GY IDTAA+Y +E+ VG Sbjct: 5 PTLNLNDGRQIP--QLGFGTWQMEEEDA----PQAVSTAIDVGYWLIDTAAIYGNEKGVG 58 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430 +G+ E ++F+ TK+WND D+ + A ++ L++LG +++D+ LIH+P Sbjct: 59 KGVGEW--------SDIFLQTKIWNDSQGYDRTLRAAEKCLERLGREHVDMLLIHWP--- 107 Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 P+ +++TW+ + + R G A+SIGVSNF + R++ + + P NQIE Sbjct: 108 ----CPEKDQFVDTWKALIELRDAGKAKSIGVSNFREEDLKRIIDETGVTPALNQIE 160 >UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6; Pezizomycotina|Rep: Aldo/keto reductase family proteins - Aspergillus oryzae Length = 294 Score = 118 bits (283), Expect = 1e-25 Identities = 71/180 (39%), Positives = 107/180 (59%), Gaps = 3/180 (1%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKES--DSID-EVRQAVYWAIEAGYRHIDTAAVYQDEE 241 P ++LND +IPI+ GTG K++ DS++ E+ +A+ AI GYRH+D A VY E Sbjct: 10 PRVKLNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGAEVYGTEA 69 Query: 242 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 421 ++G I E+ G + REELFVTTK+ + + A+ +SL+KL L+Y+DLYLIH P Sbjct: 70 ELGVAIKES---G-IPREELFVTTKVITNIA---DIPSAIDQSLRKLQLNYVDLYLIHSP 122 Query: 422 IATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 K D + + W M+ +Q G A++IGVSN++ + + + + I P NQIE Sbjct: 123 FFAKSDG-----ELQQAWAAMEKVQQAGKAKAIGVSNYHQSHLEATLKTAVIAPVINQIE 177 >UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; Sclerotiniaceae|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 360 Score = 118 bits (283), Expect = 1e-25 Identities = 66/160 (41%), Positives = 99/160 (61%), Gaps = 1/160 (0%) Frame = +2 Query: 125 GRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 304 G GT S + +AV +AIE GYR ID AAVY +E VG+GI E + + RE+++ Sbjct: 43 GFGTWNLKVSPENTTEAVAYAIEIGYRQIDCAAVYGNEVAVGRGIEEGLKRAGLKREDIW 102 Query: 305 VTTKLWNDKH-ARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQG 481 VT+KLWND H + + V L ++L+ LGL+Y+DLYLIH+PI + N+D+++T++ Sbjct: 103 VTSKLWNDHHGSYENVEKGLNQTLQDLGLEYLDLYLIHWPIGFS-SNGAKNLDHVQTYKS 161 Query: 482 MQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 M + +IGVSNF+ Q+ +VS I P +Q+E Sbjct: 162 MISLPK-SRVLNIGVSNFSPLQLKNVVSTGTI-PYMHQME 199 >UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 310 Score = 117 bits (282), Expect = 2e-25 Identities = 66/190 (34%), Positives = 115/190 (60%), Gaps = 4/190 (2%) Frame = +2 Query: 44 LNAAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAA 223 L AA+ ++LN+G +P+V +GT + +E +++ + + G+R IDTA Sbjct: 15 LEAALTPTIRDLRLNNGYDMPLVGIGTYKVRGREV-----IKRVIDESFAVGFRSIDTAV 69 Query: 224 VYQDEEQVGQGIAEAIANGLVTREELFVTTKLW-NDKHARDQVVPALQESLKKLGLDYID 400 VY++EE +G + E + + RE++F+T+KL +D D++ ++++SLK L Y+D Sbjct: 70 VYRNEEDIGLALKELLPKYNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALDTSYLD 129 Query: 401 LYLIHFPIATK-PDDSPDNIDY-LETWQGMQDARQLGLARSIGVSNFNATQITRLVSN-S 571 LYLIH+P A++ ++SPDN + TW + + +Q GL RSIGVSN+ + L+ + S Sbjct: 130 LYLIHWPGASRILENSPDNPKLRVTTWATLVELQQKGLLRSIGVSNYTVGHLEHLLEHCS 189 Query: 572 YIRPGXNQIE 601 ++P NQ+E Sbjct: 190 GVKPDVNQVE 199 >UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica; n=3; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 324 Score = 117 bits (282), Expect = 2e-25 Identities = 77/191 (40%), Positives = 105/191 (54%), Gaps = 17/191 (8%) Frame = +2 Query: 80 QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259 +LNDG++IP + LGT SD V + VY AI+ GYRHIDTA +Y E VG+GI Sbjct: 8 KLNDGHSIPALGLGTA------SDG--NVEEVVYAAIKNGYRHIDTAFIYGSEVDVGKGI 59 Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 439 AI LV RE LFVTTK+W + R V +L SLK L LDY+DL L+H+P++ D Sbjct: 60 KRAIDEELVKRENLFVTTKVWPTFYNR--VSESLDISLKDLSLDYVDLLLVHWPVSLLAD 117 Query: 440 -DSPDNI----------------DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSN 568 D P I D++ T++ +++ + G +SIGVSN + + RL+ Sbjct: 118 SDDPRAIYLVNTDGSVRYSDSLDDWITTYKQIEEEKLSGRTKSIGVSNVSEVYLKRLLDQ 177 Query: 569 SYIRPGXNQIE 601 P NQ E Sbjct: 178 VKTVPAVNQFE 188 >UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2; Ascomycota|Rep: Aldo/keto reductase family proteins - Aspergillus oryzae Length = 323 Score = 117 bits (282), Expect = 2e-25 Identities = 73/187 (39%), Positives = 102/187 (54%), Gaps = 13/187 (6%) Frame = +2 Query: 80 QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259 +LN G IP + LGT E V AV A+ AGYRHID AA YQ+E +VG G Sbjct: 8 KLNSGYNIPAIGLGTWLSKPHE------VENAVEAALRAGYRHIDAAACYQNENEVGNGW 61 Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA---T 430 ++ G V R+++F+T+KLWN H + V A+ ++LK L DY+DLYLIH+P+A T Sbjct: 62 KKS---G-VPRDQIFITSKLWNTHHHPEHVEEAVNKTLKDLQTDYLDLYLIHWPVAFEHT 117 Query: 431 KPDDSP----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 580 +P N+ +TW ++ + RSIG+SNF +I L+ + I Sbjct: 118 NETLTPIDPVTKRFRLANVPIADTWAALEKLVEAKKIRSIGISNFTQDKIDDLLKTAKIP 177 Query: 581 PGXNQIE 601 P NQIE Sbjct: 178 PAVNQIE 184 >UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; n=39; cellular organisms|Rep: NADPH-dependent aldose reductase GRE3 - Saccharomyces cerevisiae (Baker's yeast) Length = 327 Score = 117 bits (282), Expect = 2e-25 Identities = 73/196 (37%), Positives = 112/196 (57%), Gaps = 21/196 (10%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 + LN+G +P+V LG + K + +Y AI+ GYR D A Y +E++VG+G Sbjct: 5 VTLNNGLKMPLVGLGCWKIDKKVCAN------QIYEAIKLGYRLFDGACDYGNEKEVGEG 58 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA--- 427 I +AI+ GLV+R+++FV +KLWN+ H D V AL+++L +GLDY+DLY IHFPIA Sbjct: 59 IRKAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKY 118 Query: 428 ------------TKPDD------SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQIT 553 T DD + ++ ++T++ +++ GL +SIGVSNF + I Sbjct: 119 VPFEEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLIQ 178 Query: 554 RLVSNSYIRPGXNQIE 601 L+ I+P QIE Sbjct: 179 DLLRGCRIKPVALQIE 194 >UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B; n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid reductase B - Corynebacterium sp. (strain SHS752001) Length = 277 Score = 117 bits (282), Expect = 2e-25 Identities = 71/177 (40%), Positives = 100/177 (56%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P I LNDG LGT DE A+ AI++GYR +DTA Y++E +VG Sbjct: 5 PTISLNDGRPFAEPGLGTYNLRG------DEGVAAMVAAIDSGYRLLDTAVNYENESEVG 58 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430 + A+ V R+EL V +K+ +H R + V +++ SL +LGLD IDL LIH+P Sbjct: 59 R----AVRASSVDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHWP--- 111 Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 +P +L+TW+GM DAR+ GL RSIGVSNF + L+ + + P NQ+E Sbjct: 112 ----NPSVGRWLDTWRGMIDAREAGLVRSIGVSNFTEPMLKTLIDETGVTPAVNQVE 164 >UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy chain; n=3; Saccharomycetaceae|Rep: D-arabinose dehydrogenase [NAD(P)+] heavy chain - Saccharomyces cerevisiae (Baker's yeast) Length = 344 Score = 117 bits (281), Expect = 2e-25 Identities = 77/196 (39%), Positives = 109/196 (55%), Gaps = 23/196 (11%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262 LN+G IP + LGT A + + E +QAV AI+AGYRHIDTA Y+ E VG+ I Sbjct: 27 LNNGVRIPALGLGT----ANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIK 82 Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP------- 421 E + +G + RE+LF+TTK+W D+V +L ESLK LGL+Y+DL L H+P Sbjct: 83 ELLEDGSIKREDLFITTKVW--PVLWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIK 140 Query: 422 --------IATKPDDSPDNI-----DYLETWQGMQDA---RQLGLARSIGVSNFNATQIT 553 + T DDS + DYLET++ ++ R+IGVSNF+ + Sbjct: 141 DPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLE 200 Query: 554 RLVSNSYIRPGXNQIE 601 RL+ ++P NQ+E Sbjct: 201 RLIKECRVKPTVNQVE 216 >UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; Ruminococcus obeum ATCC 29174|Rep: Putative uncharacterized protein - Ruminococcus obeum ATCC 29174 Length = 263 Score = 116 bits (280), Expect = 3e-25 Identities = 70/159 (44%), Positives = 94/159 (59%) Frame = +2 Query: 125 GRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 304 G G K +D++ E A+ A++ GYR +DTA+ Y++EE VG GIA+ G V R++LF Sbjct: 5 GLGLYKTTDAV-EAEDAIAAAVQNGYRLLDTASAYKNEEFVGCGIAKC---G-VPRKDLF 59 Query: 305 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 484 +TTK+WN+ V A Q SL +LGLDYIDLYLIH+P+ +L TW+ M Sbjct: 60 ITTKIWNNAQRLGDVEGAFQRSLDRLGLDYIDLYLIHWPVPG---------CFLNTWKDM 110 Query: 485 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 + + G A SIGVSNF + L S I P NQIE Sbjct: 111 EKILESGRALSIGVSNFEIRHLEELRRVSGIVPAVNQIE 149 >UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Propionibacterium freudenreichii subsp. shermanii|Rep: Putative aldo-keto reductase - Propionibacterium freudenreichii subsp. shermanii Length = 280 Score = 116 bits (279), Expect = 4e-25 Identities = 68/177 (38%), Positives = 105/177 (59%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P ++L+ G +P++ +GT +E R AV AIE GYR +DTA Y +EE VG Sbjct: 9 PTVELSGGTRMPMLGMGTWPLKG------EECRAAVASAIEQGYRLVDTAEAYGNEEAVG 62 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430 + + EA + R E+FVTTK H+R V AL+ SL++LGLDY+DL+L+H+P+ Sbjct: 63 KAVREAGPD----RAEIFVTTKFSKQWHSRKGVHEALEHSLERLGLDYVDLFLMHWPM-- 116 Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 P Y++ ++GM + ++ GLA++IGVSNF + L++ + P NQI+ Sbjct: 117 -----PGEGSYVDAYRGMVELKEQGLAKAIGVSNFKVHHLDDLITEG-MTPEVNQIQ 167 >UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=1; Rhodobacterales bacterium HTCC2150|Rep: 2,5-diketo-D-gluconic acid reductase A - Rhodobacterales bacterium HTCC2150 Length = 334 Score = 116 bits (279), Expect = 4e-25 Identities = 74/189 (39%), Positives = 98/189 (51%), Gaps = 7/189 (3%) Frame = +2 Query: 56 MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235 M A LN TIP V GT S D+ + + AI+AGYRHIDTA+ YQ+ Sbjct: 33 MTNTATTFTLNTTTTIPAVGFGT------YLISNDDAKSTISAAIQAGYRHIDTASGYQN 86 Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHA-------RDQVVPALQESLKKLGLDY 394 E+ VG GI + + +TR++LFVT KLW A + Q + SL +LGLDY Sbjct: 87 EKTVGAGIKAGLQSAGITRKDLFVTAKLWPGNPAWGDAPKTKAQTLDECDASLARLGLDY 146 Query: 395 IDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 574 +DLYLIH P LE W+ + + + G ARSIGVSNFN + + + + Sbjct: 147 VDLYLIHAPYGGDM--------RLEQWRALLELQANGKARSIGVSNFNESHLNEIKAAGL 198 Query: 575 IRPGXNQIE 601 P NQIE Sbjct: 199 PMPDANQIE 207 >UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep: Oxidoreductase - Lactobacillus plantarum Length = 282 Score = 116 bits (278), Expect = 6e-25 Identities = 73/182 (40%), Positives = 98/182 (53%) Frame = +2 Query: 56 MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235 M V QL +G IP VA GT + E+ QAV A+ AGYRHIDTA YQ+ Sbjct: 1 MTVLTTMYQLANGVNIPKVAFGTWQIPGGEA-----TYQAVRAALAAGYRHIDTALAYQN 55 Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415 E VGQ AI + + RE++FVTTKL + + + SLK LGLDY+DLYL+H Sbjct: 56 EASVGQ----AIRDSGIPREQIFVTTKLPAETKSYQGALNDFDRSLKNLGLDYVDLYLVH 111 Query: 416 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQ 595 P + L+ WQ M+ Q G A++IGVSNF + +++ + I P NQ Sbjct: 112 APWPWGQVGRVYDEANLDVWQAMEAIYQSGRAKAIGVSNFAVRDLKNILNQATIPPMVNQ 171 Query: 596 IE 601 I+ Sbjct: 172 IQ 173 >UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase family protein; n=1; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 295 Score = 115 bits (277), Expect = 8e-25 Identities = 63/175 (36%), Positives = 103/175 (58%), Gaps = 1/175 (0%) Frame = +2 Query: 80 QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259 +L +G+ +P+ LGT + +KE E+ + A++ GYRHIDTA +Y++E+Q+G + Sbjct: 9 ELCNGSKLPVFGLGTYKVVSKE-----EMVTFLRTALDLGYRHIDTAIMYENEKQIGDAL 63 Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 439 E G RE+LF+ TKL+++K+ + V +++SL+ L +YIDLYL+H+ + D Sbjct: 64 QEIYKEGKYKREDLFLVTKLFSNKNTK--VEDQVRQSLQNLQTNYIDLYLLHYASSPPTD 121 Query: 440 D-SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 + + W ++ Q GL R+IG+SNFN + L S I+P NQIE Sbjct: 122 QFELTHKPVFQVWAEFEELVQKGLIRNIGISNFNVQMLLDLYSYCKIKPVVNQIE 176 >UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like protein 1; n=14; Eutheria|Rep: Aldo-keto reductase family 1 member C-like protein 1 - Homo sapiens (Human) Length = 302 Score = 115 bits (277), Expect = 8e-25 Identities = 58/123 (47%), Positives = 80/123 (65%) Frame = +2 Query: 65 QAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 244 Q+ ++LNDG +P++ GT A + + +A AI+ G+RHID+A +YQ+EE+ Sbjct: 7 QSHSVRLNDGPFMPVLGFGT---YAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEE 63 Query: 245 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424 VGQ I E IA+G V REE+F T KLW + V PAL+ SLKKLG DY+DL++IH P Sbjct: 64 VGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPF 123 Query: 425 ATK 433 A K Sbjct: 124 AMK 126 >UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep: Aldo/keto reductase - Kineococcus radiotolerans SRS30216 Length = 343 Score = 115 bits (276), Expect = 1e-24 Identities = 70/189 (37%), Positives = 104/189 (55%), Gaps = 12/189 (6%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P +L G T+P + +GT G+ + S + EV AV A+ AGYR +D AAVY +E QVG Sbjct: 14 PRRELRGGATVPAIGIGTF-GSDRYSPA--EVAAAVAGAVAAGYRLVDCAAVYGNEAQVG 70 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI-- 424 + +A A+A G V R+ELFV +K+WND HA V ++ SL+ L LD++D +H+P Sbjct: 71 EALAGAVAGG-VDRDELFVVSKVWNDAHAPADAVASVHRSLRDLRLDHLDAVFVHWPFPN 129 Query: 425 ---------ATKPDDSP-DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 574 A P P D+ YL W ++ GL R +G SN ++ L+ ++ Sbjct: 130 HHPPMADTDARDPRARPYDHDAYLALWGALEGLVDSGLVRHLGTSNTTVAKLDLLLRDAR 189 Query: 575 IRPGXNQIE 601 I P N++E Sbjct: 190 IPPALNEME 198 >UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon cuniculi Length = 301 Score = 115 bits (276), Expect = 1e-24 Identities = 68/185 (36%), Positives = 103/185 (55%), Gaps = 11/185 (5%) Frame = +2 Query: 80 QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259 +LN+G IP V LGT E +++ E A+ A+ GYRHIDTA +Y +E+ +G + Sbjct: 7 KLNNGKEIPTVGLGTW---GMEDEAVLE--GAIRNALSLGYRHIDTAFIYGNEKMIGNIL 61 Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA--TK 433 + G+V R++LF+T+KLWN H + L+ SL L +DY+DLYLIH+P+ Sbjct: 62 KKLFDEGVVQRKDLFITSKLWNTFHGCPE--DGLRRSLNDLQMDYVDLYLIHWPVTFDPA 119 Query: 434 PDDSPDN---------IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPG 586 PD + ++ D + W+ M+ LGLA+SIG+SNF +++ I P Sbjct: 120 PDGTVESCGKKYNVGKFDAVGVWKKMEALVDLGLAKSIGISNFGKANTEKILGTCRICPA 179 Query: 587 XNQIE 601 QIE Sbjct: 180 AIQIE 184 >UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase; n=2; Parasitella parasitica|Rep: 4-dihydromethyltrisporate dehydrogenase - Parasitella parasitica Length = 321 Score = 115 bits (276), Expect = 1e-24 Identities = 69/164 (42%), Positives = 89/164 (54%), Gaps = 17/164 (10%) Frame = +2 Query: 161 EVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR 340 + +Y AI+ GYR D A Y +E +VG+GI +AI GLV REELF+ TKLWN H++ Sbjct: 29 DAENTIYQAIKIGYRLFDGACDYGNEVEVGRGINKAIKEGLVKREELFIVTKLWNTFHSK 88 Query: 341 DQVVPALQESLKKLGLDYIDLYLIHFPIATK---------PDDSPDNIDYL--------E 469 V A LK GL+Y DLYLIHFPI + P+ + D L E Sbjct: 89 QHVRTAFDRQLKDWGLEYFDLYLIHFPIPLQYVDPAVSYPPEWYVPHADKLNFERSPIHE 148 Query: 470 TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 W M+ Q L R+IGV+NFN I L+S + I+P QIE Sbjct: 149 CWAEMEKLVQAKLTRNIGVANFNCQAILDLLSYAKIKPAVLQIE 192 >UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase family; n=1; Entamoeba histolytica HM-1:IMSS|Rep: oxidoreductase, aldo/keto reductase family - Entamoeba histolytica HM-1:IMSS Length = 307 Score = 114 bits (275), Expect = 1e-24 Identities = 74/181 (40%), Positives = 105/181 (58%), Gaps = 8/181 (4%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ-GI 259 LN+G +P + LGT EV +AV A+E GYR ID A Y++E+++G+ GI Sbjct: 8 LNNGKFMPAIGLGTWLAAP------GEVGKAVTLALENGYRLIDCARFYKNEKEIGEMGI 61 Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 439 + N REELFVT+KLW D+ R + + ES++ L Y+DLYLIH+PIA K D Sbjct: 62 EPFLKNH--PREELFVTSKLWMDQVTR--IRESCLESIQDLKCKYLDLYLIHWPIALKVD 117 Query: 440 DS----PDN---IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598 S P++ +D E WQ M+ GL +SIG+SNF QI +++ I+P NQ+ Sbjct: 118 ASNPPKPEDFLDMDITEIWQEMERLVDEGLVKSIGLSNFTIPQIEKIMKMCRIKPVINQV 177 Query: 599 E 601 E Sbjct: 178 E 178 >UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase family protein; n=3; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 299 Score = 114 bits (274), Expect = 2e-24 Identities = 63/177 (35%), Positives = 99/177 (55%), Gaps = 2/177 (1%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 I L++G +P LG+ R S++EV + A++ GYRHIDTA +Y++E+ +G Sbjct: 10 ITLSNGQKMPAFGLGSSR-----VQSVEEVTNLIRKALDVGYRHIDTAQMYENEQFIGAA 64 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 + G RE++F+ TK + K + ++E L+KL +DY+DL LIH P+A Sbjct: 65 LKTIFGEGKYKREDIFLVTKQASIKGV--SCLEIMKEQLQKLQVDYVDLLLIHVPLAAPS 122 Query: 437 DDSP--DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 DD ++ + W ++ LGLA+ +GVSNFN I L++ I+P NQIE Sbjct: 123 DDYQQWNHKPVHQIWAEFEEIHSLGLAKGLGVSNFNCQMIIDLLAYCKIKPLVNQIE 179 >UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12; Bacteria|Rep: 2,5-diketo-D-gluconate reductase - Oceanobacillus iheyensis Length = 280 Score = 114 bits (274), Expect = 2e-24 Identities = 75/182 (41%), Positives = 99/182 (54%) Frame = +2 Query: 56 MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235 M Q P + L+DG TIP V GT R +D + QA+ AI+ GYR IDTA Y++ Sbjct: 1 MVNQIPNVTLHDGLTIPKVGFGTYR--LNGNDGV----QAINNAIDHGYRLIDTAYNYEN 54 Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415 E VG EA+ RE+L +T+KL H D+ V +QESL + LDY DLYLIH Sbjct: 55 EGTVG----EAVRRSSTPREQLLITSKLPGRYHHYDKAVTTIQESLYRANLDYYDLYLIH 110 Query: 416 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQ 595 +P +P Y+E WQ + +A++ G RSIGV NF + RL + P NQ Sbjct: 111 WP-------NPIQDIYVEAWQALIEAKRRGYIRSIGVCNFLPEHLERLKQETGELPTINQ 163 Query: 596 IE 601 IE Sbjct: 164 IE 165 >UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=2; Lactobacillus|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus gasseri (strain ATCC 33323 / DSM 20243) Length = 273 Score = 114 bits (274), Expect = 2e-24 Identities = 70/175 (40%), Positives = 101/175 (57%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 + LN+ IPI GT S D+ +QAV A E GYR IDTA YQ+E+QVG+ Sbjct: 4 LTLNNDVKIPIFGFGT------YEISPDQTKQAVLSAFEEGYRLIDTAQYYQNEQQVGEA 57 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 + A+GL R+E+F+TTK D + ++ L ESL+++GLDY DL LIH+P+ Sbjct: 58 VK---ASGL-NRDEVFITTKTMTDGYEDTKI--GLDESLRRIGLDYFDLVLIHWPMGHD- 110 Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 ++TW ++ A + G R+IG+SNFN+ Q L+ S +RP +QIE Sbjct: 111 ---------IDTWHALEAAYKAGKTRAIGISNFNSRQTLDLIHQSSVRPMVDQIE 156 >UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr1 scaffold_5, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 247 Score = 114 bits (274), Expect = 2e-24 Identities = 67/179 (37%), Positives = 102/179 (56%), Gaps = 10/179 (5%) Frame = +2 Query: 92 GNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI 271 G IP+V + T S+++ + ++ AIE GYRH D A Y E+ +G+ I +A+ Sbjct: 13 GKAIPLVGMVTTVYPFAPSETMID---SILTAIELGYRHFDCVAAYLSEKPLGEAIKKAV 69 Query: 272 ANGLV-TREELFVTTKLWNDKHARDQVVPALQESLK---------KLGLDYIDLYLIHFP 421 GL+ +R+ELF+T+KLW D+V+PALQ +LK L LDY+DLYLIH+ Sbjct: 70 KLGLIKSRDELFITSKLWCSDAHHDRVLPALQNTLKISSILSFSKNLQLDYLDLYLIHWS 129 Query: 422 IATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598 P ID W+ M+D ++L L ++IGVSNF+ ++ L+ + I P NQ+ Sbjct: 130 DGHLP------IDLGSVWKAMEDFQKLSLTKAIGVSNFSCNKLEELLQTASILPAVNQV 182 >UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=4; Oligohymenophorea|Rep: Oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 297 Score = 114 bits (274), Expect = 2e-24 Identities = 64/182 (35%), Positives = 105/182 (57%), Gaps = 2/182 (1%) Frame = +2 Query: 62 VQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEE 241 V+ P + +G +IP + GT +++D I V +A ++ GY HIDTA+VY++E+ Sbjct: 11 VKVPILNFREGGSIPQIGYGTYE--LRQNDCIIGVTEA----LKIGYTHIDTASVYRNEQ 64 Query: 242 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 421 + + I A G + RE+LF+T+K+ + +Q A+Q+ L +L + Y+D LIH+P Sbjct: 65 DIAKVIHNP-AYG-IKREDLFITSKISPGEQGYEQAKKAVQDMLTRLNIKYLDCVLIHWP 122 Query: 422 IATK-PDDSPDNIDY-LETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQ 595 +K P + P N LETW+ + + R+ G+ + IGVSNFN + L+ S +P NQ Sbjct: 123 GVSKLPPNDPKNAQIRLETWKALIELRKAGVIKHIGVSNFNINHLQHLIEKSEFKPEMNQ 182 Query: 596 IE 601 E Sbjct: 183 FE 184 >UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase family protein; n=1; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 323 Score = 113 bits (272), Expect = 3e-24 Identities = 64/180 (35%), Positives = 104/180 (57%), Gaps = 5/180 (2%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 +QLN+G +P++ LGT +++E+ + A++ GYR+ DTA Y++E ++GQ Sbjct: 15 VQLNNGYKMPLLGLGTQPYDIVTRVTVEEMTTLLSNALDFGYRNFDTAKQYRNEVEIGQA 74 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF---PIA 427 G RE++F+TTKL+ K ++ +Q SL +L YIDLYLI + P+ Sbjct: 75 FQNIFQQGKYKREDVFITTKLFPFK-IEKKIKEVVQNSLDQLQTSYIDLYLIQWSFTPVL 133 Query: 428 TKPDDS--PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 T D S ++ E W+ +++ +LG+ RSIGV+NFN + L+S + I+P NQIE Sbjct: 134 TNFDGSVAVNHRPIHEVWRELEECVELGMIRSIGVANFNCQMVLDLLSYAKIKPVVNQIE 193 >UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep: Oxidoreductase - Lactobacillus plantarum Length = 288 Score = 113 bits (271), Expect = 4e-24 Identities = 72/179 (40%), Positives = 94/179 (52%) Frame = +2 Query: 65 QAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 244 + P I LNDG IP + G GT + D QAV A+ GYRHIDTA Y +E++ Sbjct: 3 KTPTITLNDGRAIPAI----GFGTFQIPDD-GSTYQAVKEALVIGYRHIDTAVAYFNEDE 57 Query: 245 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424 VGQ AI + + R++++VT+KLW + D A+ SL KL LDYIDLYLIH P Sbjct: 58 VGQ----AIKDSGIPRDQIWVTSKLWLQDYGFDAASRAIDRSLTKLRLDYIDLYLIHQPY 113 Query: 425 ATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 P WQ M+ A++ G +SIGVSN T + V P NQ+E Sbjct: 114 GDVPG----------AWQAMEAAQKAGKLKSIGVSNMTPTLWQKFVPQFETIPAVNQVE 162 >UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid reductase; n=1; Gluconobacter oxydans|Rep: Putative 2,5-diketo-D-gluconic acid reductase - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 279 Score = 113 bits (271), Expect = 4e-24 Identities = 63/175 (36%), Positives = 99/175 (56%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 I +DG+T+P + LG DE + V A++ GYR +DTA +Y++EE VG+G Sbjct: 14 ISFHDGHTMPQIGLGVWETPP------DETAEVVKEAVKLGYRSVDTARLYKNEEGVGKG 67 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 + + E+F+TTKLWND+ D + A +ES + L +DLYLIH+P+ Sbjct: 68 LED--------HPEIFLTTKLWNDEQGYDSTLRAYEESARLLRRPVLDLYLIHWPM---- 115 Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 P Y+ETW+ + + ++ G +SIGVSNF + + R++ + + P NQIE Sbjct: 116 ---PAQGQYVETWKALVELKKSGRVKSIGVSNFESEHLERIMDATGVVPVVNQIE 167 >UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales bacterium HTCC2654 Length = 278 Score = 113 bits (271), Expect = 4e-24 Identities = 74/178 (41%), Positives = 103/178 (57%) Frame = +2 Query: 68 APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247 AP + L +G +P + LGT T DE +AV AIE GYR IDTA Y++E V Sbjct: 7 APTVTLANGVEMPQLGLGTWPMTD------DEAAKAVATAIETGYRLIDTAENYKNETGV 60 Query: 248 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427 GQGI +A G V R+E+F+TTK+ H+ D A + SL++LGLDYIDL+LIH+P Sbjct: 61 GQGIRDA---G-VARDEVFLTTKMNKQWHSVDGARRACEASLERLGLDYIDLFLIHWP-- 114 Query: 428 TKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 +PD Y+E ++G+ GL R+IG SNF + L + ++ P NQI+ Sbjct: 115 -----NPDQGTYVEAFEGLTRLLDAGLVRAIGTSNFLPHHLNDLFAAGFV-PHVNQIQ 166 >UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: Aldehyde reductase - Lactobacillus acidophilus Length = 278 Score = 112 bits (270), Expect = 5e-24 Identities = 64/175 (36%), Positives = 100/175 (57%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 + LN+G +P + G + D + + +Q V +E GYR +DTA +Y +E+ VG Sbjct: 5 VTLNNGIKMPRLGFGV-----YQIDDLAQAQQVVEDGLEVGYRLVDTAQIYGNEQAVG-- 57 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 +AI + V RE++F+T+K+W D + D + A +S+KKL LDYIDLYLIH P Sbjct: 58 --DAIKHSNVPREDIFITSKIWVDDYGYDNTLKAFDDSMKKLQLDYIDLYLIHKPYN--- 112 Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 DY TW+ ++ Q G R+IGVS+F ++ L++ + ++P NQIE Sbjct: 113 -------DYYGTWRALERLYQEGRIRAIGVSSFWNERLADLITFNDVKPAVNQIE 160 >UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family; n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto reductase family - Lactobacillus acidophilus Length = 289 Score = 112 bits (270), Expect = 5e-24 Identities = 70/177 (39%), Positives = 96/177 (54%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P I+LNDGN IP + G + + DE +AV AI GYR IDTA Y ++ VG Sbjct: 5 PKIKLNDGNEIPQLGFGVF-----QISNHDEAVKAVESAISNGYRLIDTAEAYNNQTAVG 59 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430 EAI N V R+++F+TTKLW ++ A+ E LK+LG DYID+ L+H Sbjct: 60 ----EAIKNSDVNRDDIFLTTKLWVSNFTYEKASKAIDEDLKELGTDYIDMMLLHQAYG- 114 Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 D W+ ++DA++ G +SIGVSNF Q+ L S ++P NQIE Sbjct: 115 ---------DVAGAWRALEDAQKAGKTKSIGVSNFWPDQLMNLQLMSNVKPVVNQIE 162 >UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Lactobacillus brevis ATCC 367|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 268 Score = 112 bits (270), Expect = 5e-24 Identities = 66/174 (37%), Positives = 103/174 (59%) Frame = +2 Query: 80 QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259 QL++G TIP++ GT +K+ V A+ A++AGYRH+D A +Y +E VG+ I Sbjct: 5 QLSNGVTIPMLGFGTYLIDSKD------VPAAIKTALDAGYRHLDCAHIYGNEPAVGEAI 58 Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 439 A+G + R +LF+T+K+WN D+ + A ++L L LDY+DLYLIH+P D Sbjct: 59 K---ASG-IDRSDLFITSKVWNADQGYDKTLAAFDQTLSDLQLDYLDLYLIHWP---NED 111 Query: 440 DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 D +D TW+ ++ Q R+IGVSNF+ Q+ ++ + ++P NQIE Sbjct: 112 DFELTLD---TWRVLETLYQQKKVRAIGVSNFSEDQLKQVFEMATVKPMINQIE 162 >UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep: AkrI - Butyrivibrio fibrisolvens Length = 172 Score = 112 bits (270), Expect = 5e-24 Identities = 57/153 (37%), Positives = 94/153 (61%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 I+LN+G IP+ G GT K D +E +V A++ GYRHIDTAA Y++E+ V Sbjct: 8 IKLNNGTAIPMF----GYGTYKIKDQ-NEAYNSVRLALKNGYRHIDTAAFYENEKFVANA 62 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 I + + RE++FVT+K W + D+ + A ++++ ++ +DY+DLYL+H+P + Sbjct: 63 IKDFMEESQTKREDIFVTSKAWKTELGYDKTLAAFEKTMNEMQMDYLDLYLVHWPASYAF 122 Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNF 535 DD +N + +TW+ M + + G ++IGVSNF Sbjct: 123 DDDWENTN-RQTWKAMTEIYKSGRVKAIGVSNF 154 >UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293|Rep: Aldo/keto reductase of diketogulonate reductase family - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 288 Score = 112 bits (269), Expect = 7e-24 Identities = 65/160 (40%), Positives = 92/160 (57%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262 LN+G +P + G + A+E+ +QAV AI AGYR IDTA VY +E + GQG+ Sbjct: 6 LNNGAQMPQLGFGVFQIPAEET------KQAVVDAINAGYRSIDTARVYGNEAETGQGVN 59 Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 442 EAIAN +V REELF+TTKLW + + + A+ +SLKKLG DY DL L+H P Sbjct: 60 EAIANAVVAREELFLTTKLWLSEFSYEAAKGAIDDSLKKLGTDYADLILLHQPYG----- 114 Query: 443 SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 562 D ++ + +A+ G +SIG+SNF + + Sbjct: 115 -----DVYGAYKALAEAQADGKVKSIGISNFYPAKFVEFI 149 >UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=9; Trichomonas vaginalis G3|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 308 Score = 112 bits (269), Expect = 7e-24 Identities = 68/185 (36%), Positives = 100/185 (54%), Gaps = 16/185 (8%) Frame = +2 Query: 95 NTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIA 274 N IP + LGT + E D V Y EAGY HID A Y++E+ VGQ + + Sbjct: 2 NRIPTIGLGTWKSPRSE----DLVNAITYAIKEAGYVHIDCALCYENEDIVGQALQQCWD 57 Query: 275 NGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA--------- 427 +G + RE +++T+KLWN H + V A +++LK L LDY+DLYL+H+P A Sbjct: 58 SG-IKRENIWITSKLWNTHHRLEIVEEACRKTLKDLRLDYLDLYLMHYPFAFQNTGIGGS 116 Query: 428 TKPDDS------PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRL-VSNSYIRPG 586 P D D + ++TW+ M+ + GL + IGVSN+ Q+ RL S++ P Sbjct: 117 LNPLDEKGNTIFDDGVSLIDTWKAMEKLVEKGLVKRIGVSNWTINQLERLKYSDAKTTPY 176 Query: 587 XNQIE 601 NQ+E Sbjct: 177 TNQVE 181 >UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Lin2349 protein - Listeria innocua Length = 294 Score = 111 bits (267), Expect = 1e-23 Identities = 69/171 (40%), Positives = 99/171 (57%), Gaps = 1/171 (0%) Frame = +2 Query: 92 GN-TIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEA 268 GN TIP + LG + T +E + AV AIE GYR DTAAVY +E VGQ A Sbjct: 13 GNETIPYIGLGVFQVTEQEF-----IAGAVEKAIEVGYRLFDTAAVYNNEAIVGQ----A 63 Query: 269 IANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSP 448 I + V REELF+++K+WN D+ + A + +L+ L LDY+DLYLIH+P+A K Sbjct: 64 ILDSAVPREELFISSKVWNGDLGYDETLFAFERTLRNLKLDYLDLYLIHWPVAGK----- 118 Query: 449 DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 Y ++W+ M+ L +SIGV+NF ++ L+ + +P NQ+E Sbjct: 119 ----YRDSWRAMERLHDEKLIKSIGVANFKQHHLSDLLVAANEKPVLNQVE 165 >UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4; Bifidobacterium|Rep: Dehydrogenase or reductase protein - Bifidobacterium longum Length = 289 Score = 111 bits (267), Expect = 1e-23 Identities = 69/177 (38%), Positives = 98/177 (55%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P I L DG++IP V LG R + + + V ++ A+EAGYRHID AA Y +E VG Sbjct: 12 PDIALKDGHSIPQVGLGVLR---IDDEGVVPVVES---ALEAGYRHIDGAAGYNNEAGVG 65 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430 + +A + N RE L+VTTKL + + D + A SLK L LDY+D+Y+IH+P Sbjct: 66 RALAASGYNKGAKRETLWVTTKLRDSQQGYDSALKAFDNSLKLLQLDYVDMYMIHWP--- 122 Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 +P + +TW+ R G+AR++GV NF + RL + P NQIE Sbjct: 123 ----TPFDWRSTDTWKAFVKLRDEGMARTLGVCNFMPADLKRLHEETGAWPAVNQIE 175 >UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; Lactobacillus reuteri|Rep: 2,5-didehydrogluconate reductase - Lactobacillus reuteri F275 Length = 300 Score = 111 bits (267), Expect = 1e-23 Identities = 68/178 (38%), Positives = 104/178 (58%), Gaps = 1/178 (0%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P I+LN+G+ IP + LG + S+ E +Q V AI Y IDTA Y +E VG Sbjct: 11 PKIKLNNGHLIPQLGLGVWKA------SLAETQQMVKEAIMNDYVLIDTAKQYGNEAAVG 64 Query: 251 QGIAEAIANGLVTREELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427 QGI + R+ +F+TTK++N D+ D++ A+ E LKKL +Y+DL L+H+P+ Sbjct: 65 QGIQDGFKATGRKRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLLLHWPVN 124 Query: 428 TKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 K Y E+W+ ++D + G A++IGV NFN ++T L+ ++ I+P NQIE Sbjct: 125 DK---------YNESWRALEDIYKDGQAKAIGVCNFNVERMTDLLDHAKIKPAINQIE 173 >UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium discoideum AX4 Length = 305 Score = 111 bits (267), Expect = 1e-23 Identities = 69/185 (37%), Positives = 106/185 (57%), Gaps = 10/185 (5%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 I LN+ N PI G GT K ++++ + +E GYR IDTA++Y +EE++G+ Sbjct: 15 IILNELNLNPIKMPMLGIGTFK----LNDIENIIKVGLENGYRRIDTASMYNNEERIGKV 70 Query: 257 IAEAIA--NGL----VTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 418 + E + +GL + RE+LF+T+K + + + A + SLKKL LDY+D YLIH+ Sbjct: 71 LNEMVTKNDGLDGKKIKREDLFITSKCSFMEQGYENALKAFESSLKKLQLDYLDCYLIHW 130 Query: 419 PIATKPD--DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVS--NSYIRPG 586 P D DS ++I +TW+ ++ Q RSIGVSN+ +T L+S N I+P Sbjct: 131 PGVKGLDGSDSGNSIQRAQTWRALEKLYQDKKVRSIGVSNYTINHLTELLSSPNLQIKPA 190 Query: 587 XNQIE 601 NQ+E Sbjct: 191 INQVE 195 >UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=10; Pezizomycotina|Rep: Related to aldo-keto reductase YPR1 - Neurospora crassa Length = 322 Score = 111 bits (267), Expect = 1e-23 Identities = 69/184 (37%), Positives = 99/184 (53%), Gaps = 7/184 (3%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQ----AVYWAIEAGYRHIDTAAVYQDE 238 P ++L+DGN IP++ G G K DS D + + A A+ AGY H+D A VY +E Sbjct: 25 PSLKLSDGNEIPMLGYGLGTANYKSGDSADTISEPIVNATLTALNAGYAHLDGAEVYGNE 84 Query: 239 EQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 418 ++G+ AIA + R L++TTK A D V + SL+KLGLDY+DLYL+H Sbjct: 85 VELGR----AIAQSKLPRSSLYITTK--TIVRAGDTVTQSFNRSLEKLGLDYVDLYLLHS 138 Query: 419 PIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV---SNSYIRPGX 589 P K +P+ + W+ M+ + G+A+SIGVSNF + + L P Sbjct: 139 PFFAK---NPEQLQ--AAWREMEKIKDSGMAKSIGVSNFLISHLQTLFDIPGGLQYPPVV 193 Query: 590 NQIE 601 NQIE Sbjct: 194 NQIE 197 >UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20; Bacteria|Rep: 2,5-diketo-D-gluconate reductase - Acinetobacter sp. (strain ADP1) Length = 297 Score = 111 bits (266), Expect = 2e-23 Identities = 68/177 (38%), Positives = 104/177 (58%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P + L+DG++IP ALG G T K +D + +A + GYR +D+A Y++E VG Sbjct: 23 PDLILHDGHSIP--ALGFGTYTLKGQQGVDTMLRA----LGHGYRMLDSAFNYENEGAVG 76 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430 + ++ GL+ R+E+F+T+KL HA D+ + ++ESL ++ DY+DLYLIH+P Sbjct: 77 AAVRQS---GLL-RDEIFITSKLPGRHHAYDKAMETIEESLYRMQFDYLDLYLIHWP--- 129 Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 +P Y+E WQ + DA++ G RSIGVSNF I L + + P NQ+E Sbjct: 130 ----NPQQGLYIEAWQALIDAQKKGYIRSIGVSNFLPKHIETLRRETGVIPVINQVE 182 >UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus terreus NIH2624|Rep: Predicted protein - Aspergillus terreus (strain NIH 2624) Length = 292 Score = 111 bits (266), Expect = 2e-23 Identities = 69/183 (37%), Positives = 100/183 (54%), Gaps = 6/183 (3%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKE--SDSID-EVRQAVYWAIEAGYRHIDTAAVYQDEE 241 P + L DGN +PI+ GTG K+ +D + E+ + + A+E G+ HID A Y E Sbjct: 4 PALSLKDGNLVPILGFGTGTAWYKDDPNDPTNPELIEVLKAALEKGFHHIDAADSYGTER 63 Query: 242 QVGQGIAEAIANGLVTREELFVTTKL---WNDKHARDQVVPALQESLKKLGLDYIDLYLI 412 +VG I E+ G + RE+LF+TTK+ W D V AL SL++L LDY+DLYL+ Sbjct: 64 EVGIAIRES---G-IPREQLFITTKVLEGWKD------VPGALDASLERLQLDYVDLYLL 113 Query: 413 HFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXN 592 H P P+ D W+G++ + G ARSIGVSNF + ++ + P N Sbjct: 114 HNPYVI-----PNLTDIQSAWKGLEAVKATGKARSIGVSNFQRNHLEAILETCSVVPAIN 168 Query: 593 QIE 601 Q+E Sbjct: 169 QLE 171 >UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep: NADH/NADPH dependent indole-3-acetaldehyde reductase AKR3C2 - Schizosaccharomyces pombe (Fission yeast) Length = 284 Score = 111 bits (266), Expect = 2e-23 Identities = 71/172 (41%), Positives = 94/172 (54%), Gaps = 2/172 (1%) Frame = +2 Query: 92 GNTIPIVALGTGRGT-AKESDSIDE-VRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAE 265 G IP+ A G G KE I+ + +V A+ AG+ HID A VY +EE+VG + E Sbjct: 7 GPKIPVPAYGVGTALFKKEKGEINRTIVDSVKNALAAGFIHIDCAEVYGNEEEVGVALKE 66 Query: 266 AIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDS 445 A V R +LF+T+K+ H D + AL ESL+KLG DY+DLYL+H PI Sbjct: 67 AN----VPRSKLFITSKVM---HNVDNIPEALNESLRKLGTDYLDLYLLHSPIPFYEKKI 119 Query: 446 PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 P + E W+ M+ A GL S+GVSNF + L+ S I P NQIE Sbjct: 120 PIS----EGWKAMETALGTGLVHSVGVSNFRIPDLEELLKTSTITPRVNQIE 167 >UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Griffithsia japonica|Rep: Mannose 6-phosphate reductase - Griffithsia japonica (Red alga) Length = 174 Score = 102 bits (245), Expect(2) = 2e-23 Identities = 51/110 (46%), Positives = 73/110 (66%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262 L G +P+ GT + S++E QAV A+ AGYRHID AAVY +E VG I+ Sbjct: 8 LQSGAKMPLNGFGTWKA------SVEETEQAVTAALRAGYRHIDCAAVYWNEAAVGTAIS 61 Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLI 412 +AI+ G+V RE+LF+T+K+WN HA D+VV + ++SLK +DY DL+L+ Sbjct: 62 KAISGGVVKREDLFITSKVWNTCHATDKVVDSCRQSLKDHQVDYFDLFLV 111 Score = 29.1 bits (62), Expect(2) = 2e-23 Identities = 14/38 (36%), Positives = 21/38 (55%) Frame = +2 Query: 488 DARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 D L L R IGVSN++ + ++ + I+P NQ E Sbjct: 104 DYFDLFLVRDIGVSNYSVALLVDTLNYARIKPSVNQCE 141 >UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase; n=1; Rhodococcus sp. RHA1|Rep: Probable 2,5-didehydrogluconate reductase - Rhodococcus sp. (strain RHA1) Length = 265 Score = 110 bits (265), Expect = 2e-23 Identities = 64/147 (43%), Positives = 87/147 (59%) Frame = +2 Query: 161 EVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR 340 + +AV IEAGYR IDTA +Y +E+ VG +AE G V REELFVTTKL H Sbjct: 18 DATRAVLSGIEAGYRLIDTATIYDNEDAVGVALAEC---G-VPREELFVTTKLRGSDHVS 73 Query: 341 DQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSI 520 + A++ SLK LGLD +DL+LIH+P+ P + Y+ ++ M R GL R + Sbjct: 74 GDIRGAVERSLKNLGLDRLDLFLIHWPL-------PRHNRYVAAFEAMLACRDAGLVRHV 126 Query: 521 GVSNFNATQITRLVSNSYIRPGXNQIE 601 GVSNF T + R+V+ + P NQI+ Sbjct: 127 GVSNFLETHLRRVVAETGESPAVNQIQ 153 >UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phytophthora infestans|Rep: Aldo-keto reductase, putative - Phytophthora infestans (Potato late blight fungus) Length = 255 Score = 110 bits (265), Expect = 2e-23 Identities = 66/182 (36%), Positives = 100/182 (54%) Frame = +2 Query: 56 MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235 M+V P L G IP++ LG +S+ E A+ +++ GYRHIDTA +Y + Sbjct: 1 MSVNVPTKILPSGARIPMIGLGV-----YQSEPGPETYNAILTSLKLGYRHIDTAEIYGN 55 Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415 EE VG+ A+ + + REE+FVTTKL+ + + A + S +LG+ YI LYL+H Sbjct: 56 EEDVGR----AVRDSGIPREEIFVTTKLFTTNWGYSKALAAGKASNDRLGIVYIYLYLLH 111 Query: 416 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQ 595 P K + +TW+ ++D R+ R IGVSNFN T + L ++I+P NQ Sbjct: 112 APGPPK--------ERADTWRAVEDLREQETLRDIGVSNFNETLLATLRKTAHIKPAVNQ 163 Query: 596 IE 601 +E Sbjct: 164 VE 165 >UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter sp. (strain FB24) Length = 287 Score = 110 bits (264), Expect = 3e-23 Identities = 66/181 (36%), Positives = 104/181 (57%) Frame = +2 Query: 59 AVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDE 238 A P ++L G+TIP + LGT DE AV +A+++GYR +DTA Y++E Sbjct: 10 ASDIPRLKLPHGHTIPRLGLGTWPMLE------DECETAVRFALQSGYRLVDTAFQYRNE 63 Query: 239 EQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 418 E VG+GI A G V R ELF+++K + H+ D V A ESL+KLGLD++D+++ H+ Sbjct: 64 EAVGRGIRTA---G-VPRSELFISSKFNKESHSIDGVQRAYDESLRKLGLDHLDMFMCHW 119 Query: 419 PIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598 P+ P Y++ W+G+ + G ++IGVSNF + ++ + + P NQI Sbjct: 120 PV-------PALGKYVDAWKGLVKLLEEGRVKAIGVSNFKPAHLKDIIDATGVVPDVNQI 172 Query: 599 E 601 + Sbjct: 173 Q 173 >UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1; n=2; Caenorhabditis|Rep: Putative uncharacterized protein T08H10.1 - Caenorhabditis elegans Length = 333 Score = 110 bits (264), Expect = 3e-23 Identities = 65/187 (34%), Positives = 106/187 (56%), Gaps = 12/187 (6%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 I LN G +P+ LGT + K+ E+ A+ A++AGYR IDTA +YQ+E +G+ Sbjct: 6 IPLNTGAQLPLFGLGTWQ--VKDEA---ELTVALRAALDAGYRLIDTAHLYQNEHIIGKV 60 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 + E I++G + RE++FVT+KL HA + V ++ LK L L+YIDLYLIH P K Sbjct: 61 LHEYISSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLYLIHCPFPFKH 120 Query: 437 DD------------SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 580 + + I +++TW+ ++ + G +++GVSNF+ Q+ L + ++ Sbjct: 121 QEGSFAPLMENGELAVTEIAHIDTWRALEKLYKEGKLKALGVSNFSCNQLQALYDAAEVK 180 Query: 581 PGXNQIE 601 P Q+E Sbjct: 181 PANQQVE 187 >UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several dehydrogenases of different specificities; n=4; Pezizomycotina|Rep: Similarity: shows similarity to several dehydrogenases of different specificities - Aspergillus niger Length = 381 Score = 110 bits (264), Expect = 3e-23 Identities = 69/194 (35%), Positives = 107/194 (55%), Gaps = 19/194 (9%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 + LN G IP + GT + +V AVY A++AGYRH+D A +YQ++ +V +G Sbjct: 7 VTLNSGAQIPQLGFGTWQSAP------GQVGDAVYEALKAGYRHLDLATIYQNQREVAEG 60 Query: 257 IAEAIAN--GLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA- 427 I A + GL RE++F+T+KLWN +H V AL E L +L LDY+DLYL+H+P++ Sbjct: 61 IKRAYKDVPGL-KREDIFITSKLWNSQHDPAVVEKALDECLAELELDYLDLYLVHWPVSF 119 Query: 428 -TKPDDSP---------------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRL 559 T + P D+I ++TW+ M + AR++GVSN + + Sbjct: 120 TTGSELFPLVKDSSVEGGDVVINDDISIVDTWKAMTQLPK-SKARTVGVSNHMIPHLEAI 178 Query: 560 VSNSYIRPGXNQIE 601 ++ + + P NQIE Sbjct: 179 INATGVVPAVNQIE 192 >UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Staphylococcus|Rep: Oxidoreductase, aldo/keto reductase family - Staphylococcus epidermidis (strain ATCC 35984 / RP62A) Length = 279 Score = 109 bits (263), Expect = 4e-23 Identities = 64/173 (36%), Positives = 100/173 (57%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262 LN+G +P V LG K +D +++ + V A++AGYR DTA Y +E+ +G Sbjct: 8 LNNGYPMPAVGLGV----YKIAD--EQMEEVVRTALDAGYRAFDTAYFYGNEKALGS--- 58 Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 442 A+ + V R+ELF+T+KLWND DQ + +SL LGLDY+DL+LIH+P Sbjct: 59 -ALKHSNVERDELFITSKLWNDYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWPCEN---- 113 Query: 443 SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 D + Y+E+++ ++ + G ++IGV NF + +L+ + I P NQIE Sbjct: 114 --DQL-YIESYKALEHLYEEGKIKAIGVCNFKIHHLEKLMKETKITPQVNQIE 163 >UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|Rep: Reductase AKOR2 - Pleurotus djamor Length = 306 Score = 109 bits (263), Expect = 4e-23 Identities = 72/191 (37%), Positives = 105/191 (54%), Gaps = 14/191 (7%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P I LN G +P +ALG G +E + + ++ A+++GYRHIDTA +Y E+ VG Sbjct: 5 PPIVLNTGARMPALALGGWAGLTEEERT--QAKEWFLTALKSGYRHIDTAQIYYTEKSVG 62 Query: 251 QGIAEAIANGLVTREELFVTTKL-WNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427 I E+ G + REELF+TTKL WN H+R V + Q+SL+ LG +YIDLYL+HFP Sbjct: 63 NAIRES---G-IPREELFITTKLPWNH-HSR--VAESFQKSLENLGTEYIDLYLVHFPQR 115 Query: 428 TKPD---DSPDNID----------YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSN 568 D D P N D + W ++ G ++IGVSN++ + L+ Sbjct: 116 VFYDETTDFPRNPDGSIKVVNSPTLNDVWADVETLLDTGKVKAIGVSNYSIKTLEELLKT 175 Query: 569 SYIRPGXNQIE 601 + + P NQ+E Sbjct: 176 AKVVPAVNQVE 186 >UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose reductase; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to aldose reductase - Strongylocentrotus purpuratus Length = 274 Score = 109 bits (261), Expect = 7e-23 Identities = 58/147 (39%), Positives = 86/147 (58%) Frame = +2 Query: 161 EVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR 340 +V AV AI+ GYRHID A VY +E +VG G+ E +V RE++F+T+KLWN+KH Sbjct: 11 QVEAAVKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLWNNKHHP 70 Query: 341 DQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSI 520 D V A +LK L L Y+DLYL+H+P+A +Q M+ G ++I Sbjct: 71 DDVEQACDITLKNLQLSYVDLYLMHWPMA---------------YQAMEKLVTSGKCKAI 115 Query: 521 GVSNFNATQITRLVSNSYIRPGXNQIE 601 G+SNF+ + R++ + I+P Q+E Sbjct: 116 GLSNFSMKMMKRVIEKATIQPANLQVE 142 >UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Lin2848 protein - Listeria innocua Length = 280 Score = 109 bits (261), Expect = 7e-23 Identities = 66/174 (37%), Positives = 103/174 (59%) Frame = +2 Query: 80 QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259 +LN+G +P G G K +D +R A+ A++ GYR DTA+ Y +E+++G Sbjct: 10 RLNNGIEMP----RHGFGVYKLTDE-QRMRTALETAVDVGYRLFDTASFYHNEKELGDFF 64 Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 439 A ++GL R+E FVTTK+WN + D+ + A ++S KKL LD +DLYL+H+P K D Sbjct: 65 A---SSGL-KRDEFFVTTKMWNTEQGYDETLRAFEKSQKKLQLDQVDLYLVHWP---KQD 117 Query: 440 DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 + ETW+ ++ GL R+IGVSNF A + RL +++ + P +Q+E Sbjct: 118 ------TFFETWRAVEKLYDEGLVRAIGVSNFEAHHLDRLRTSANVLPVVDQLE 165 >UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 284 Score = 109 bits (261), Expect = 7e-23 Identities = 69/184 (37%), Positives = 108/184 (58%), Gaps = 2/184 (1%) Frame = +2 Query: 56 MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235 M+ +AP ++LN+G +P++ LGT +KE + ++ ++ A I+AGYRHIDTA YQ+ Sbjct: 1 MSPKAPMVKLNNGLEMPVLGLGTW--LSKEGEGVEAIKAA----IDAGYRHIDTAYFYQN 54 Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKL--WNDKHARDQVVPALQESLKKLGLDYIDLYL 409 E++VG+ I I G+V RE+LFVTTK W+ K+ ++P ++ KL +D Sbjct: 55 EKEVGEAIRAKIEEGVVCREDLFVTTKFIDWDTKN----LMP--YDADGKLQFSDVD--- 105 Query: 410 IHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGX 589 Y++TW+ M+ + G +SIGVSNFN+ QITRL++ I+P Sbjct: 106 -----------------YIDTWKAMEKLLKTGKVKSIGVSNFNSEQITRLLAECEIKPVT 148 Query: 590 NQIE 601 NQ+E Sbjct: 149 NQVE 152 >UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Filobasidiella neoformans|Rep: Aldo-keto reductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 303 Score = 109 bits (261), Expect = 7e-23 Identities = 64/175 (36%), Positives = 96/175 (54%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 ++++DGN IP LG KE+ V WA+EAGYRH+DTA Y++E G+ Sbjct: 33 LKMHDGNAIPQFGLGVYEMNDKET------YDCVKWALEAGYRHVDTAEWYENEAPCGKA 86 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 IA+ + +REE+F+T+KL N+ + +Q L+ SLK+ G++Y DLYL+H I Sbjct: 87 IADFLKATGTSREEIFLTSKLKNNS-SYEQAFVDLKGSLKRSGVEYFDLYLMHSAIG--- 142 Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 P + W+ + DA+ GL +SIGVSNF I + P NQ++ Sbjct: 143 --GP--VIRKNVWKALCDAQSQGLVKSIGVSNFGKKHIQEFIDQKVPLPTVNQVD 193 >UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 700 Score = 109 bits (261), Expect = 7e-23 Identities = 70/176 (39%), Positives = 102/176 (57%), Gaps = 17/176 (9%) Frame = +2 Query: 125 GRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 304 G GT K S ++ AV AI+ GYRHID A Y++E+ V GI +A G V R +L+ Sbjct: 24 GFGTWKMSK--EQATPAVAHAIKTGYRHIDCAWAYRNEDAVAAGIKKA---G-VPRSQLW 77 Query: 305 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA----------------TKP 436 +T+KLWN H + V AL SLK LG DY+DLYL+H+P+A P Sbjct: 78 LTSKLWNSFHHPEHVEKALDASLKDLGTDYLDLYLMHWPVAFLNSKGSMVPSIRSTGGHP 137 Query: 437 DDSPD-NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 +S D + D++ T++ M++ + G R+IGVSNFN + + +V + I+P NQ+E Sbjct: 138 VESEDLSRDFMATYRVMEEMVKKGKVRNIGVSNFNIRRTSEVVDEASIKPVVNQVE 193 >UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 353 Score = 108 bits (260), Expect = 9e-23 Identities = 76/214 (35%), Positives = 120/214 (56%), Gaps = 17/214 (7%) Frame = +2 Query: 11 SLLRIITLTCL-LNAAMAVQAPCI-QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYW 184 S + + TL C+ ++ + V+A + +L+ G+ PIV LGT G + D + + Sbjct: 7 SFVLLATLCCVSISYSQNVEAGTVYRLSSGHNFPIVGLGT-HGLNE-----DVLETVLTG 60 Query: 185 AIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKL-WNDKHARDQVVPAL 361 A+E G HIDT+ VY++EE +G+ + + A G RE++FVT+KL + D H + V + Sbjct: 61 ALEKGIGHIDTSFVYKNEETIGKVLKDWFAKG-GKREDIFVTSKLPYYDNHP-ESVEKYI 118 Query: 362 QESLKKLGLDYIDLYLIHFP-----------IATKPDDS---PDNIDYLETWQGMQDARQ 499 + SL+KLGL Y+D+YLIH P +AT D S D + W+ M+ + Sbjct: 119 KLSLEKLGLQYLDMYLIHAPFAVHHKEDSYELATNEDGSVVLDTQTDPIAVWKEMEKQVK 178 Query: 500 LGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 G +SIG+SNFN TQIT ++ + I+P Q+E Sbjct: 179 EGRTKSIGLSNFNETQITNILKEAKIKPSNLQVE 212 >UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; Bacteria|Rep: 2,5-didehydrogluconate reductase - Arthrobacter sp. (strain FB24) Length = 291 Score = 108 bits (259), Expect = 1e-22 Identities = 70/191 (36%), Positives = 102/191 (53%), Gaps = 13/191 (6%) Frame = +2 Query: 68 APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247 +P + LN+G + I LG G +D+ V A +EAGYRH DTAA+Y +E V Sbjct: 4 SPRLSLNNG--VLIDQLGFGLYKVPPADAAGLVTMA----LEAGYRHFDTAAMYGNETGV 57 Query: 248 GQGIAE--AIANG-----------LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGL 388 G+ I A G ++RE+LFVTTK+WND H D + A S+ LG+ Sbjct: 58 GKAIGALAGFAGGGPAGGSGEAAPSLSREDLFVTTKVWNDDHGYDATMRAFDTSMSNLGM 117 Query: 389 DYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSN 568 +Y+DLYLIH+P A + + E+++ M+ + G R+IGVSNF + L+ Sbjct: 118 EYVDLYLIHWPCARRG-------LFTESYRAMETLYREGRIRAIGVSNFQPAHLEHLLET 170 Query: 569 SYIRPGXNQIE 601 + + P NQIE Sbjct: 171 AEVVPAVNQIE 181 >UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to CG2767-PA - Nasonia vitripennis Length = 356 Score = 107 bits (256), Expect = 3e-22 Identities = 68/189 (35%), Positives = 108/189 (57%), Gaps = 14/189 (7%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 I+L+ G+ +P++ LGT + + + AV A+E+GYRHIDTA Y +EE +G+ Sbjct: 28 IKLSSGHDMPMIGLGTWQMPP------EAIEVAVTAALESGYRHIDTAFTYGNEEAIGKT 81 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA--- 427 + + G RE+LF+TTKL + V L+ SL+KLGL+Y+++YLIH P A Sbjct: 82 LKKWFDKG-GKREDLFITTKLPPIGMRAEYVESYLKLSLEKLGLEYVNMYLIHKPFAFVK 140 Query: 428 ----TKPDDSPD-------NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 574 +P +PD + D++ W+ M+ + G RSIG+SNFN +Q+ + ++ Sbjct: 141 DKYKYEPALNPDGSVVLDTDTDHVAIWRAMEKQVKAGRVRSIGLSNFNKSQLLNVYEHAE 200 Query: 575 IRPGXNQIE 601 I+P QIE Sbjct: 201 IKPSNLQIE 209 >UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycoplasma gallisepticum Length = 289 Score = 107 bits (256), Expect = 3e-22 Identities = 61/159 (38%), Positives = 92/159 (57%) Frame = +2 Query: 125 GRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 304 G GT K D V +AV A+E GYRH+D A +Y+++ V QGI +G V R+E+F Sbjct: 26 GFGTYKLEDGKQTV-EAVKTALEVGYRHLDCAEIYENQLSVSQGIK---LSG-VNRKEIF 80 Query: 305 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 484 +T+K+WND + A + LK L L+Y+DL LIH+PI D+ ++ +TW+ M Sbjct: 81 ITSKIWNDDKGYESTKKAFHKILKDLDLEYLDLLLIHWPIGKGFKDNWQEVN-AQTWKAM 139 Query: 485 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 ++ G ++IG+SNF I L ++ I P NQ+E Sbjct: 140 EEFYLEGKIKAIGLSNFLVHHIEALKKSAKILPMVNQLE 178 >UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome chr1 scaffold_22, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 360 Score = 107 bits (256), Expect = 3e-22 Identities = 68/185 (36%), Positives = 107/185 (57%), Gaps = 12/185 (6%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262 LN IP + LGT + D +AV A+ GYR ID A +Y +E +VG+ +A Sbjct: 14 LNTKAKIPAIGLGTWQSGG------DLCVEAVKRALSEGYRQIDCAHLYGNEVEVGEALA 67 Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP------I 424 EA NG + RE++F+T+KL+ ++ +++ +++ SLK LG+ Y+DLYL+H+P Sbjct: 68 EAF-NGSLKREDVFLTSKLYCTMNSLNKIENSVRVSLKNLGVTYLDLYLMHWPDITAFGD 126 Query: 425 ATKP--DDSPDNIDYL----ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPG 586 AT P + D+ +L + W+ M+ +LGL R+IGVSNF QI L+ + I P Sbjct: 127 ATDPPSNSGNDHRQFLNRLKKAWKAMEGLIELGLVRAIGVSNFGVQQIKELLKFAKIVPA 186 Query: 587 XNQIE 601 NQ++ Sbjct: 187 VNQVK 191 >UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; Saccharomycetales|Rep: Probable oxidoreductase YJR096W - Saccharomyces cerevisiae (Baker's yeast) Length = 282 Score = 107 bits (256), Expect = 3e-22 Identities = 70/179 (39%), Positives = 103/179 (57%), Gaps = 5/179 (2%) Frame = +2 Query: 80 QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259 +L++G IP +ALGT ++ I VY ++ GYRH DTA +Y +E++VG GI Sbjct: 7 KLSNGFKIPSIALGTYDIPRSQTAEI------VYEGVKCGYRHFDTAVLYGNEKEVGDGI 60 Query: 260 AEAIAN--GLVTREELFVTTKLWNDKHARDQVVPALQESLKKL-GLDYIDLYLIHFPIAT 430 + + G REE+F TTKLWN ++ + A+++ L ++ GL YIDL LIH P+ Sbjct: 61 IKWLNEDPGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSPL-- 118 Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RPGXNQIE 601 + S LETW+ MQ+A GL +SIGVSN+ I L++ + +P NQIE Sbjct: 119 --EGSKLR---LETWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWPELKHKPVVNQIE 172 >UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep: Aldo-keto reductase - Helicobacter hepaticus Length = 292 Score = 106 bits (254), Expect = 5e-22 Identities = 68/176 (38%), Positives = 98/176 (55%), Gaps = 4/176 (2%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262 LN+GN IP + LGT R D++ V AV A + GYRHIDTA Y +E +G+ Sbjct: 17 LNNGNKIPKLGLGTWR----IDDNV--VEAAVREAFKVGYRHIDTAQAYGNE----RGVG 66 Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 442 EA+ + REELF+T+K+ + ++ SLK + LD+IDL LIH P +P + Sbjct: 67 EAVRKSKIKREELFITSKIRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSP---QPWN 123 Query: 443 SPDNIDY----LETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598 S DY +E + ++DA++ G RSIGVSNF + ++ N +P NQI Sbjct: 124 SFRKGDYFKENVEVYNALEDAQKAGKVRSIGVSNFLQKDLENILKNCKTKPAANQI 179 >UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; Klebsiella pneumoniae|Rep: Putative uncharacterized protein - Klebsiella pneumoniae Length = 279 Score = 106 bits (254), Expect = 5e-22 Identities = 65/175 (37%), Positives = 102/175 (58%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 I LNDG +P G ++ DS+ +RQA ++AG+RH DTA Y +E+ VG+ Sbjct: 6 ILLNDGYYMPRPGCGLWLIDNRDVDSL--IRQA----LKAGFRHFDTAQAYFNEDGVGR- 58 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 A+ V RE+LF+T+K+ + + + E+L++LG++Y++L+LIH+PI K Sbjct: 59 ---ALRYTEVPREQLFITSKIRGRDMGYARTLVSFNETLERLGVEYLELFLIHWPIPAK- 114 Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 N+ Y+ETW+ + GL RSIGVSNF I RL+ ++ + P NQ+E Sbjct: 115 -----NL-YVETWEASIELEASGLIRSIGVSNFTCQHIERLIEDTGVVPAVNQLE 163 >UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteobacteria|Rep: Aldo/keto reductase - Pseudoalteromonas atlantica (strain T6c / BAA-1087) Length = 273 Score = 106 bits (254), Expect = 5e-22 Identities = 55/136 (40%), Positives = 86/136 (63%) Frame = +2 Query: 158 DEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHA 337 D+ + AV A++ GYRHIDTA Y++E +VG +AI+ ++R ELFVTTK+W D + Sbjct: 24 DDAKLAVENALDVGYRHIDTAQAYENEAEVG----DAISASKISRGELFVTTKVWFDNLS 79 Query: 338 RDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARS 517 D+ + ++Q SL +L DY+DL L+H+P PD+ +YL+ ++ ++ GL R Sbjct: 80 ADKFITSVQNSLTQLNTDYVDLLLVHWP---SPDNKVSMAEYLKE---LKACKERGLTRH 133 Query: 518 IGVSNFNATQITRLVS 565 IGVSNF +Q+ +S Sbjct: 134 IGVSNFTQSQLDEALS 149 >UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; Bacteria|Rep: Putative uncharacterized protein - Bacteroides capillosus ATCC 29799 Length = 287 Score = 106 bits (254), Expect = 5e-22 Identities = 65/175 (37%), Positives = 100/175 (57%), Gaps = 2/175 (1%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262 L++G +IP V G GT K D V AI GYRH DTA+ Y E +GQ +A Sbjct: 10 LSNGLSIPAV----GFGTYKTGDGDSAVLSN---AIAQGYRHFDTASFYGTETALGQAVA 62 Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 442 E+ + RE+ F+T+KLW + D + A +L++LG DY+DLYLIH+P +PD Sbjct: 63 ESD----IPREDFFLTSKLWKTEMGYDAALRAFDATLERLGTDYLDLYLIHWP---RPDL 115 Query: 443 SPDNIDYL--ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 ++ L ETW+ ++ + GL R+IGVSNF + +++++ + P +Q+E Sbjct: 116 ELEDWAKLDRETWRALERLYESGLVRAIGVSNFLPHHLEPILASANVAPMVDQLE 170 >UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coagulans 36D1|Rep: Aldo/keto reductase - Bacillus coagulans 36D1 Length = 273 Score = 106 bits (254), Expect = 5e-22 Identities = 59/172 (34%), Positives = 97/172 (56%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262 L +G IP + LGT + E+ AV +A++ GYRHIDTA Y +EE VG+ Sbjct: 10 LENGVAIPKIGLGTWQVPNGET-----TYHAVSFALKNGYRHIDTAYAYHNEESVGK--- 61 Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 442 A+ + + R ++FVT+KL + + D+ + E++ GL+ +DLYLIH P Sbjct: 62 -AVRDSGIDRRDIFVTSKLPAEIKSYDKALKTFDETMGNFGLEQLDLYLIHAPWPWSEKG 120 Query: 443 SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598 + + +E W+ M++ + G R+IGVSNF+ + + ++ N+ I+P NQI Sbjct: 121 ADYTKENIEVWKAMEEIYESGRCRAIGVSNFSVSDLKAVMENAKIKPMVNQI 172 >UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - Trichoderma atroviride (Hypocrea atroviridis) Length = 327 Score = 106 bits (254), Expect = 5e-22 Identities = 66/189 (34%), Positives = 102/189 (53%), Gaps = 16/189 (8%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262 LN G IP V G GT + E AV A++ GYRH+D A Y +E++VG I Sbjct: 17 LNTGAKIPAV----GFGTFANEGAKGETYAAVTKALDVGYRHLDCAWFYLNEDEVGDAIR 72 Query: 263 EAIANGL-VTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 439 + +A VTR++LF+ TK+WN H + V + + S + L +DYIDL+L+H+PIA + + Sbjct: 73 DFLARRPDVTRKDLFICTKVWNHLHEPEDVKWSAKNSCENLKVDYIDLFLVHWPIAAEKN 132 Query: 440 D------SPDNIDYLE---------TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 574 PD + TW+ M++ G+ ++IGVSN+ + +L+ + Sbjct: 133 ADRTVKIGPDGKYVINKALTENPEPTWRAMEELVDSGIVKAIGVSNWTIPGLKQLLEFAR 192 Query: 575 IRPGXNQIE 601 I+P NQIE Sbjct: 193 IKPAVNQIE 201 >UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep: Aldo/keto reductase - Mesorhizobium sp. (strain BNC1) Length = 308 Score = 105 bits (253), Expect = 6e-22 Identities = 60/148 (40%), Positives = 87/148 (58%) Frame = +2 Query: 158 DEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHA 337 DE AV A+ GYRHIDTAA Y +E +VG+GI A G + R+E+F+ TK+W + Sbjct: 42 DETTAAVEEALRLGYRHIDTAAAYGNEREVGEGIRRA---G-IARDEVFIETKIWISDYG 97 Query: 338 RDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARS 517 D+ + A +S KLG+D IDL L+H P+ + D + L ++ ++ G R+ Sbjct: 98 YDETLHAFDKSAGKLGVDQIDLLLLHQPLPSAFDRT------LGAYRALEKLLADGKVRA 151 Query: 518 IGVSNFNATQITRLVSNSYIRPGXNQIE 601 IGVSNF +TRL++ + I P NQIE Sbjct: 152 IGVSNFMPEHLTRLLTETSIVPAVNQIE 179 >UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 292 Score = 105 bits (253), Expect = 6e-22 Identities = 65/185 (35%), Positives = 101/185 (54%) Frame = +2 Query: 47 NAAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAV 226 NA + P L G+ IP++ GT + A E D+ D V +A +E GYRHIDTA + Sbjct: 9 NAPASSPIPTFMLPTGSPIPVLGFGTYK-VAPE-DTYDAVSRA----LEVGYRHIDTAQM 62 Query: 227 YQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLY 406 Y +E +VG + A+G + RE+LF+TTK+ N H D+ +++ SL+ L DY+DL Sbjct: 63 YGNEAEVGAALE---ASG-IAREDLFITTKVDNSNHEPDRAAASIRRSLEDLRTDYVDLL 118 Query: 407 LIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPG 586 L+H+P+ T D W ++DA G AR+IG+SN+ + + + + P Sbjct: 119 LVHWPLPTLYGG-----DVALPWPALEDAFNAGGARAIGLSNYEREHVEAVREVATVAPH 173 Query: 587 XNQIE 601 Q+E Sbjct: 174 VLQVE 178 >UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; Clostridium beijerinckii NCIMB 8052|Rep: 2,5-didehydrogluconate reductase - Clostridium beijerinckii NCIMB 8052 Length = 289 Score = 105 bits (252), Expect = 8e-22 Identities = 56/148 (37%), Positives = 83/148 (56%) Frame = +2 Query: 158 DEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHA 337 ++ AV AI+ GYRH DTA +Y +E+ +G AI + REE F+T+K+WN H Sbjct: 30 EDFETAVGEAIKIGYRHFDTAKIYGNEKDLGL----AIEKSQIPREEFFITSKVWNTDHG 85 Query: 338 RDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARS 517 + A +++ KKL ++Y+D+YLIHF + YLETW M++ G + Sbjct: 86 YEATKKAFEQTCKKLNVEYLDMYLIHFASSY----------YLETWHAMEELYLQGKIKV 135 Query: 518 IGVSNFNATQITRLVSNSYIRPGXNQIE 601 IGV+NF + L+ +S I P NQIE Sbjct: 136 IGVANFQIQHLEELMKHSRITPMINQIE 163 >UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B; n=91; Proteobacteria|Rep: 2,5-diketo-D-gluconic acid reductase B - Yersinia pestis Length = 267 Score = 105 bits (252), Expect = 8e-22 Identities = 62/146 (42%), Positives = 90/146 (61%) Frame = +2 Query: 98 TIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIAN 277 +IP+ LGT R ++ ID V QA + GYR IDTA +Y++E VGQ I E+ N Sbjct: 2 SIPVFGLGTFR--LQDQIVIDSVSQA----LTLGYRAIDTAQIYENEAPVGQAIQESGIN 55 Query: 278 GLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNI 457 R+ELF+TTK+W ++D+++P+L+ES++KL DY+DL LIH+P P+ D + Sbjct: 56 ----RDELFITTKIWIANLSKDKLIPSLRESIQKLKTDYVDLTLIHWP---SPN---DEV 105 Query: 458 DYLETWQGMQDARQLGLARSIGVSNF 535 E + A+ LGL R IG+SNF Sbjct: 106 SVAEFMSELLKAKGLGLTRQIGISNF 131 >UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "AKR1B1 protein. - Takifugu rubripes Length = 330 Score = 104 bits (250), Expect = 1e-21 Identities = 54/118 (45%), Positives = 73/118 (61%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P + LN G +P++ LGT K + +AV AI AGYRHIDTA VY++E +VG Sbjct: 3 PSVTLNTGALMPVLGLGTW----KSGKGV--TTEAVKVAIGAGYRHIDTAYVYENETEVG 56 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424 G+ I G+V REELF+ +KLW H V A +++L L LDY+DLYL+HFP+ Sbjct: 57 AGVQAMIDQGVVKREELFIVSKLWCTFHTPSLVRGACEKTLSSLNLDYVDLYLMHFPM 114 Score = 46.8 bits (106), Expect = 4e-04 Identities = 21/53 (39%), Positives = 34/53 (64%), Gaps = 2/53 (3%) Frame = +2 Query: 449 DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RPGXNQIE 601 D +L+TW+ M++ GLA++IG+SNFN QI +++ + +P NQIE Sbjct: 158 DGTSFLDTWEAMEELVDDGLAKAIGISNFNKDQIEAVLNKPGLKHKPATNQIE 210 >UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 339 Score = 104 bits (250), Expect = 1e-21 Identities = 74/199 (37%), Positives = 102/199 (51%), Gaps = 17/199 (8%) Frame = +2 Query: 56 MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235 MA P LN G +P V +G +G +E+ A+ AI+ GYRH+DTA Y++ Sbjct: 1 MAANIPSFTLNTGAKLPSVGMGCWQGQPGPGRD-NELVDALVRAIKVGYRHLDTATGYRN 59 Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415 E +VGQ A+ V R E+FVTTKL D VV L+ SL +LG+DYIDL+L+H Sbjct: 60 EAEVGQ----AVRQSGVARSEIFVTTKL-RPGGVHD-VVQELENSLNELGIDYIDLWLLH 113 Query: 416 FPIATKPDDSP---------DNIDYL-----ETWQGMQDA---RQLGLARSIGVSNFNAT 544 +P DD ++ +L ETW M+D G ++IGVSNF+ Sbjct: 114 WPQGFTKDDGGFGTGESFGLEHQKHLGPTFNETWAKMEDVFLNSHKGKVKAIGVSNFSIK 173 Query: 545 QITRLVSNSYIRPGXNQIE 601 + L S + P NQIE Sbjct: 174 NLEILAKTSKVTPAVNQIE 192 >UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter sp. (strain FB24) Length = 281 Score = 104 bits (249), Expect = 2e-21 Identities = 67/177 (37%), Positives = 97/177 (54%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P + LN+G IP + G + +E+ I E A+EAGYRHIDTAA Y++E VG Sbjct: 10 PQLTLNNGVKIPQLGFGVFQVPPEETQRIVED------ALEAGYRHIDTAAAYRNEAGVG 63 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430 I+ A+G + RE++F+TTKL N + A Q S K LG++++DLYLIH+P+ Sbjct: 64 AAIS---ASG-IPREDIFITTKLRNGEQGNAH--EAFQNSRKALGVEFVDLYLIHWPV-- 115 Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 P Y E W+ M+ R+IGVSNF + L+ + + P NQ+E Sbjct: 116 -----PSQGLYTEAWKAMEKLYANSQIRAIGVSNFLGEHLDTLLPAADVVPAVNQVE 167 >UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n=1; Rhizobium leguminosarum bv. viciae 3841|Rep: Putative aldo-keto reductase/oxidase - Rhizobium leguminosarum bv. viciae (strain 3841) Length = 274 Score = 103 bits (247), Expect = 3e-21 Identities = 60/133 (45%), Positives = 82/133 (61%) Frame = +2 Query: 152 SIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDK 331 S DE Q V WA+EAG RHIDTA Y +E+ V +GI +A G V R E+F+TTK+ D Sbjct: 21 SADEAHQGVIWALEAGCRHIDTAQGYGNEQDVARGIKDA---G-VARNEIFITTKVKPDN 76 Query: 332 HARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLA 511 + V+P+++ESL+KL +D +DL L+H+P P + DYL + + D+ GLA Sbjct: 77 YGPGAVMPSVRESLEKLRVDQVDLLLLHWP---SPHNKYPLADYLGQFAEVFDS---GLA 130 Query: 512 RSIGVSNFNATQI 550 R IGVSNF I Sbjct: 131 RQIGVSNFTKAMI 143 >UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; Parvularcula bermudensis HTCC2503|Rep: Putative uncharacterized protein - Parvularcula bermudensis HTCC2503 Length = 278 Score = 103 bits (247), Expect = 3e-21 Identities = 63/156 (40%), Positives = 93/156 (59%) Frame = +2 Query: 104 PIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGL 283 PI LG G + D+ R + AIE GYRHID AA+Y++E++VG+GI ++ G Sbjct: 10 PIPRLGFGTWQLEGEDA----RTSTRTAIETGYRHIDGAAIYKNEKKVGEGIKDS---G- 61 Query: 284 VTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDY 463 + R+ELFVTTK+WN+ + + A+ ESL +LGLDY++L L+H+PI P D + Sbjct: 62 IPRDELFVTTKIWNEDIQKGRHSEAVDESLDRLGLDYVNLILLHWPINDMP--IADQVGP 119 Query: 464 LETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 571 L + ++ G A+ IG+SN+N Q VS S Sbjct: 120 L------AEIKRSGRAKLIGISNYNQAQFLEAVSAS 149 >UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 287 Score = 103 bits (246), Expect = 4e-21 Identities = 62/179 (34%), Positives = 102/179 (56%), Gaps = 2/179 (1%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P ++L G +P++ LGT K D ++++Q+V A++AGYR DTAAVY +E +G Sbjct: 4 PSVRLMSGTQMPLLGLGT----YKLQDH-EQLKQSVSCALQAGYRAFDTAAVYGNEAHLG 58 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP--I 424 Q + E + + RE++F+ +KL H L+ SL++L +YIDLYLIH+P Sbjct: 59 QVLKELLPKYGLIREDVFIISKLAPSDHGLRAKEGCLR-SLEQLDCEYIDLYLIHWPGME 117 Query: 425 ATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 P+DS + ++W +++ G ++IGVSN+ A I L+++ + P QIE Sbjct: 118 GLDPEDSRHSEYRAQSWATLEEFHASGQFKAIGVSNYTAKHIRELLASCRVPPAVLQIE 176 >UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobacillus acidophilus|Rep: Reductase-dehydrogenase - Lactobacillus acidophilus Length = 271 Score = 103 bits (246), Expect = 4e-21 Identities = 69/176 (39%), Positives = 91/176 (51%), Gaps = 3/176 (1%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262 LN+G IP + LGT + DEV + V A+ GYR DTA Y +E VG+GI Sbjct: 9 LNNGEKIPQIQLGTWL------INNDEVNKVVRQAVNIGYRGFDTAKDYGNESGVGKGIW 62 Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP---IATK 433 N + R ++F+TTKL + A+ +L K GL+YIDL LIH P I Sbjct: 63 ----NSDIERSDIFLTTKLPTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQPWIEVN 118 Query: 434 PDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 + LE W+ M++A + G RSIGVSNF I +V+N I P NQIE Sbjct: 119 RTNDRHFKGNLENWRAMEEAVKAGKVRSIGVSNFLQEDIENIVNNGTITPAVNQIE 174 >UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; Parabacteroides merdae ATCC 43184|Rep: Putative uncharacterized protein - Parabacteroides merdae ATCC 43184 Length = 301 Score = 103 bits (246), Expect = 4e-21 Identities = 72/185 (38%), Positives = 99/185 (53%) Frame = +2 Query: 47 NAAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAV 226 NA + P ++LN+G +P LG G K D + V AI+ G+R IDTA Sbjct: 22 NAQEMNKVPTVKLNNGMEMP--QLGVGTFLVK-----DNAAERVCHAIKVGFRLIDTAQG 74 Query: 227 YQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLY 406 Y +E++VG+GI + G + R ELF+TTK+ + V +L +SL LG DYIDL Sbjct: 75 YGNEKEVGEGICRS---G-IDRRELFITTKVNTMEMRGGTVRQSLDKSLADLGTDYIDLV 130 Query: 407 LIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPG 586 LIH+P+ ETWQ +++ G RSIGVSNFN + L+ + IRP Sbjct: 131 LIHWPVKG---------HIKETWQILEEYVDKGKIRSIGVSNFNPHHLDELLEYARIRPV 181 Query: 587 XNQIE 601 NQIE Sbjct: 182 VNQIE 186 >UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3; Saccharomycetales|Rep: Conjugated polyketone reductase C1 - Candida parapsilosis (Yeast) Length = 304 Score = 103 bits (246), Expect = 4e-21 Identities = 66/192 (34%), Positives = 109/192 (56%), Gaps = 10/192 (5%) Frame = +2 Query: 56 MAVQAPCIQLNDGNTIPIVALGTGRGTAKE--SDSIDEVRQAVYWAIEAGYRHIDTAAVY 229 M++ +L++GN IP VA GTG K +D ++ + A+ +G+RHID A +Y Sbjct: 1 MSLAGKEFKLSNGNKIPAVAFGTGTKYFKRGHNDLDKQLIGTLELALRSGFRHIDGAEIY 60 Query: 230 QDEEQVGQGIAEAIANGLVTREELFVTTKL------WNDKHARDQ-VVPALQESLKKLGL 388 +++G A+ N + R+++F+T K ++ KH++ Q AL+ L+ LGL Sbjct: 61 GTNKEIGI----ALKNVGLNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLGL 116 Query: 389 DYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV-S 565 +Y+DLYLIHFP + + D +E W+ ++ A+ GLAR+IGVSNF + ++ + Sbjct: 117 EYVDLYLIHFPYIS---EKSHGFDLVEAWRYLERAKNEGLARNIGVSNFTIENLKSILDA 173 Query: 566 NSYIRPGXNQIE 601 N+ P NQIE Sbjct: 174 NTDSIPVVNQIE 185 >UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Saccharomycetales|Rep: D-arabinose dehydrogenase - Pichia stipitis (Yeast) Length = 326 Score = 102 bits (245), Expect = 6e-21 Identities = 67/194 (34%), Positives = 105/194 (54%), Gaps = 21/194 (10%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262 L++G TIP + LGT + E+++ V A++AGYRHIDTA Y EE +GQ + Sbjct: 12 LSNGKTIPALGLGT-----VPPEDPHELKEQVITAVKAGYRHIDTAWYYGTEEYIGQALK 66 Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA----- 427 + G+V RE+LF+TTK+W + +L +SL LGLDY+DL+L H+P+ Sbjct: 67 QLFEEGIVKREDLFITTKVWPSFWRNPE--KSLDKSLADLGLDYVDLFLQHWPVVLHGDE 124 Query: 428 ----TKP---------DDSP-DNIDYLETWQGMQDAR-QLGLARSIGVSNFNATQITRLV 562 +P DD P I Y++ + ++D +SIGVSN++ ++ +L+ Sbjct: 125 NGLPPQPRDKDGKLIYDDDPVSGIKYIDAYHSLEDIMDNTSKVKSIGVSNYSIPKLRKLL 184 Query: 563 SN-SYIRPGXNQIE 601 + +P NQIE Sbjct: 185 AAVRKHKPVVNQIE 198 >UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia ATCC 50803 Length = 313 Score = 102 bits (244), Expect = 8e-21 Identities = 55/163 (33%), Positives = 93/163 (57%), Gaps = 15/163 (9%) Frame = +2 Query: 158 DEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI--ANGLVTREELFVTTKLWNDK 331 + V+ AV A+ GYRHID A VYQ+EE +G+ + A+ + RE++++T+KLWN Sbjct: 17 EAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKREDVWITSKLWNYN 76 Query: 332 HARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPD-------------NIDYLET 472 H + V ++++ L +DY+DL+L+H+P+A +D D + +T Sbjct: 77 HRPELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEGRAMLEKVPLADT 136 Query: 473 WQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 W+ M+ + GL + IGVSN+ + L++ + I+P NQIE Sbjct: 137 WRAMEQLVEEGLVKHIGVSNYTVPLLADLLNYAKIKPLVNQIE 179 >UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 297 Score = 102 bits (244), Expect = 8e-21 Identities = 58/177 (32%), Positives = 100/177 (56%), Gaps = 3/177 (1%) Frame = +2 Query: 80 QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259 +LN G IP V GT + T + V A+ A+ AGYR DTA Y +E+++G+ + Sbjct: 14 KLNSGYNIPFVGFGTYKVTG------ENVPPAIDAALTAGYRMFDTAKYYLNEKELGEAL 67 Query: 260 AEAIANGLVTREELFVTTKLW-NDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 + ++R ++F+T+K + K+ R+ ++ESL+ L DYID+YL+H+P Sbjct: 68 KILLPKHGLSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYPKPNDS 127 Query: 437 D-DSPDNIDYLE-TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 D D +N +Y + ++ +++A+ G RSIGVSN+ + L + + + P NQ+E Sbjct: 128 DNDDVNNAEYRKIAYEVLEEAKAAGKVRSIGVSNYEIVHLEELKTYAKVPPCANQLE 184 >UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 - Apis mellifera Length = 292 Score = 101 bits (243), Expect = 1e-20 Identities = 62/177 (35%), Positives = 96/177 (54%), Gaps = 4/177 (2%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262 L+ G +P++ GT + +E V Q V ++ G+R IDTA Y++EE +G + Sbjct: 10 LSSGYDMPLIGFGTYKIQGREL-----VYQVVDESLNVGFRSIDTAVGYRNEEDIGYALK 64 Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQ-VVPALQESLKKLGLDYIDLYLIHFPIATK-P 436 + + R ++F+TTKL + + + +Q+SLK YIDLYLIH+P AT+ P Sbjct: 65 NLLPKYNLQRSDIFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYLIHWPGATRIP 124 Query: 437 DDSPDNIDY-LETWQGMQDARQLGLARSIGVSNFNATQITRLVSN-SYIRPGXNQIE 601 + S +N +TW + D ++ G RSIGVSNF + L+ N I P NQ+E Sbjct: 125 ETSTNNPSLRAKTWNKLVDLKKQGFIRSIGVSNFTIKHLQELLQNCKDILPAVNQVE 181 >UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 286 Score = 101 bits (243), Expect = 1e-20 Identities = 72/188 (38%), Positives = 103/188 (54%), Gaps = 6/188 (3%) Frame = +2 Query: 56 MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235 MA +L +G+T+P + LGT +G D ++V+ V AI+AGYRHID AA Y + Sbjct: 1 MATPTASFRLVNGSTLPAIGLGTFQG----DDGNEKVKNIVKAAIQAGYRHIDGAAAYGN 56 Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415 EE +G I E +G ++R+EL + W H V AL SL+ LGL+Y+ Sbjct: 57 EEAIGDAIKE---SG-ISRDEL---AQPW---HEPKDVERALDLSLEALGLEYV------ 100 Query: 416 FPIATKPDDSPDNID------YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 577 P A P P+N+D Y ETWQ M+ G A++IG+SNFN + R++ + I Sbjct: 101 -PHAYLP--GPNNVDYERSRKYTETWQAMEKLVDSGKAKAIGLSNFNILKTKRILEIARI 157 Query: 578 RPGXNQIE 601 RP NQ+E Sbjct: 158 RPAVNQVE 165 >UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA - Apis mellifera Length = 321 Score = 101 bits (241), Expect = 2e-20 Identities = 63/188 (33%), Positives = 103/188 (54%), Gaps = 13/188 (6%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 I L +G +PI+ GT + KE + A+ A+EAGYRHIDTA Y++E+ +G Sbjct: 6 ILLPNGELMPIIGFGTWQAQEKE------LEDALNIALEAGYRHIDTATSYENEKVIGDV 59 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK- 433 + + + R ++F+ TKL + + V ++ SL+ L L+Y+DLYLIH PI + Sbjct: 60 LKNWFDSKKLKRSDIFIVTKLPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLIHVPIGFEK 119 Query: 434 ------PDDSPDNI------DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 577 P D +I +++E W M+ + G ++IG+SNFN +QI R++ N+ + Sbjct: 120 VGDILHPFDENGHIRLDNSTNHVEIWAEMEKQVKCGRTKAIGLSNFNISQIKRILKNTKM 179 Query: 578 RPGXNQIE 601 + QIE Sbjct: 180 KISMLQIE 187 >UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; Trypanosomatidae|Rep: Aldo-keto reductase-like protein - Leishmania major strain Friedlin Length = 372 Score = 100 bits (240), Expect = 2e-20 Identities = 62/180 (34%), Positives = 90/180 (50%), Gaps = 18/180 (10%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 I + D +TIP + GT R + E AV +A+ GYRH+D A Y +E VG+ Sbjct: 22 IAMRDSHTIPQLGFGTYRLP------VSEATDAVAFALSCGYRHVDCAKAYGNEAAVGEA 75 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 +A+A+ RE+LFVT+KLW D V A + +L L LDY+DLYLIH+P+ + Sbjct: 76 LAQALRTRCTRREDLFVTSKLWPTDQHPDHVEAACRATLAALQLDYLDLYLIHWPVCMRH 135 Query: 437 ---------------DDSP---DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 562 D +P ++ L+TW M GL +SIG++N + LV Sbjct: 136 TPHWTSDEDRYPRHRDGTPAIDTSVTLLDTWTAMNRLVDRGLVKSIGLANCTTAHVNDLV 195 >UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto reductase family 1, member B10, partial; n=1; Macaca mulatta|Rep: PREDICTED: similar to aldo-keto reductase family 1, member B10, partial - Macaca mulatta Length = 275 Score = 100 bits (239), Expect = 3e-20 Identities = 61/164 (37%), Positives = 93/164 (56%), Gaps = 8/164 (4%) Frame = +2 Query: 134 TAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTT 313 T K + +V++AV AI+AGYRHID A VYQ+E +VG+ I E I V RE+LF+ + Sbjct: 38 TRKPKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVS 97 Query: 314 K------LWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETW 475 K LW R V A +++LK L L Y+D+YLIH+P + + Sbjct: 98 KVHMAHWLWTTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWP---------------QGF 142 Query: 476 QGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RPGXNQIE 601 + M++ GL +++G+SNFN QI +L++ + +P NQ+E Sbjct: 143 KAMEELVDEGLVKALGISNFNHFQIEKLLNKPGLKYKPVTNQVE 186 >UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 320 Score = 100 bits (239), Expect = 3e-20 Identities = 61/177 (34%), Positives = 98/177 (55%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P ++L G +P +A GTG SD+ +V A +++G+R ID A VY +E +G Sbjct: 4 PTVRLASGLELPRLAFGTGTALYN-SDAAKQVTMA----LDSGFRFIDGAEVYANEASMG 58 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430 GI +A+ + R +++V TK+ K + A++ L+KL +D +D YL+H P Sbjct: 59 AGIESFLASSGLKRNDIYVLTKV--GKEGMKDLQSAIKVELQKLKVDQLDSYLLHLPPRG 116 Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 + D P N+D W+ ++ +Q GL +SIGVSN+ A+ I +L+ P NQIE Sbjct: 117 Q-DGLPSNVD---AWKELEKIKQAGLTKSIGVSNWLASDIQQLLDAGLSVPDINQIE 169 >UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Rep: YvgN - Bacillus sp. NRRL B-14911 Length = 268 Score = 99 bits (238), Expect = 4e-20 Identities = 63/181 (34%), Positives = 95/181 (52%), Gaps = 6/181 (3%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAV---YWAIEAGYRHIDTAAVYQDEEQV 247 I LN+G +PIV GT + +D ++ + AIE GYR ID A +Y++EE V Sbjct: 4 ITLNNGLEMPIVGTGTNTYGKENNDYNGDLTNEIPELASAIELGYRSIDAAIMYRNEELV 63 Query: 248 GQGIAEAIANGLVTREELFVTTKLWNDKH---ARDQVVPALQESLKKLGLDYIDLYLIHF 418 G +AE+ V REE F+TTK+ + +++ A+ SLK DY+DL LIHF Sbjct: 64 GSVLAES----KVPREEFFITTKIPASEEYISSKEATRAAIDNSLKNFQTDYLDLLLIHF 119 Query: 419 PIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598 PI D + TW+ ++ + G ++IGVSNF + L + ++P NQI Sbjct: 120 PIE-------DKVQLKNTWEVFEEYYEAGKLKAIGVSNFEENHLDELKEFAKVKPAVNQI 172 Query: 599 E 601 + Sbjct: 173 Q 173 >UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 355 Score = 85.8 bits (203), Expect(2) = 4e-20 Identities = 56/143 (39%), Positives = 82/143 (57%), Gaps = 13/143 (9%) Frame = +2 Query: 212 DTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLD 391 D A +Y +E +VGQGI A+G V R ELFVTTK+W H + + L ESL++LGLD Sbjct: 80 DAAWIYGNENEVGQGIK---ASG-VPRSELFVTTKIWCTYHRQPEA--CLDESLQRLGLD 133 Query: 392 YIDLYLIHFPIA-TKPDDS--PDNIDYL----------ETWQGMQDARQLGLARSIGVSN 532 Y+DL L+H+P+ K D P N D +TW+ M+ G ++IGVSN Sbjct: 134 YVDLLLVHWPVPLVKRGDEKIPLNEDGSRAIDRDWSPEQTWELMEKLPATGKTKAIGVSN 193 Query: 533 FNATQITRLVSNSYIRPGXNQIE 601 ++ + +L++ + I P NQ+E Sbjct: 194 WSIAFLDKLLAKAKIVPAANQVE 216 Score = 34.7 bits (76), Expect(2) = 4e-20 Identities = 20/44 (45%), Positives = 26/44 (59%) Frame = +2 Query: 80 QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHI 211 +LN G IP++ LGT + EV +AV AI+AGYRHI Sbjct: 15 KLNTGAEIPVIGLGTWQSAP------GEVAKAVESAIKAGYRHI 52 >UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 287 Score = 99.5 bits (237), Expect = 5e-20 Identities = 57/171 (33%), Positives = 98/171 (57%), Gaps = 2/171 (1%) Frame = +2 Query: 95 NTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI- 271 N +P++ +GT + +E +RQ + + GYR IDTA VY +E ++G+ + + + Sbjct: 9 NNMPLIGIGTWQVQKEEI-----LRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEKLLP 63 Query: 272 ANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPD 451 ANGL RE++++T+KL + +++ESL L ++Y+DL LIH+P ++ ++P Sbjct: 64 ANGL-KREDIWITSKLAPSNAGVKKARESIEESLSNLKVEYLDLLLIHWPGSSLKSENPA 122 Query: 452 NIDY-LETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 N +E+W M + G RS+GVSNF + L +S + P NQ+E Sbjct: 123 NKKLRVESWNVMCEMMAEGKLRSVGVSNFEICHLEELKKDSNVVPAVNQVE 173 >UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica; n=1; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 302 Score = 99.5 bits (237), Expect = 5e-20 Identities = 63/179 (35%), Positives = 100/179 (55%), Gaps = 2/179 (1%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDE--VRQAVYWAIEAGYRHIDTAAVYQDEEQ 244 P ++L++G IP + G+G + +E + AV AI AG+ HIDTA Y E+Q Sbjct: 4 PKVKLSNGLEIPAIGFGSGTKWKRPPGEKEERELIDAVVSAINAGHLHIDTAEFYGTEKQ 63 Query: 245 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424 +G+ I E+ G V R+++F+T+K A D + ++ LK L DY DL+LIH P Sbjct: 64 IGEAIKES---G-VPRKDIFLTSKTLFGLLA-DDPIESISNQLKTLQTDYFDLFLIHVP- 117 Query: 425 ATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 P+D N D + W ++ + GLA++IGVSN + ++ ++ + I+P NQIE Sbjct: 118 ---PNDDI-NYDLAKAWGVLEQLYEKGLAKAIGVSNHSPAELETIIKVAKIKPHVNQIE 172 >UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep: ENSANGP00000029046 - Anopheles gambiae str. PEST Length = 331 Score = 99.1 bits (236), Expect = 7e-20 Identities = 63/188 (33%), Positives = 101/188 (53%), Gaps = 14/188 (7%) Frame = +2 Query: 80 QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259 +LN G IP+ GT + +E + Q + +A+EAGYRHIDTA VY++EE +G + Sbjct: 35 KLNTGFDIPLAGFGTYQIHGQEL-----IYQVLDYALEAGYRHIDTAVVYRNEEYIGTAL 89 Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPAL-QESLKKLGLDYIDLYLIHFP-IATK 433 + + RE++F+T+KL + + V + ++SL L DY+DLYLIH+P ++ K Sbjct: 90 KTLLPKYNLKREDIFITSKLISQSGKDEAFVEQMVRKSLANLQTDYLDLYLIHWPGVSGK 149 Query: 434 ----------PDDSPDNIDY-LETWQGMQDARQLGLARSIGVSNFNATQITRLVSN-SYI 577 PDN+ Y +W + + G RSIGVSN+ + ++++ I Sbjct: 150 CGRWKWLFGMQVTHPDNVKYRAASWNALSKLEREGCLRSIGVSNYTVKHLKEMLADCKGI 209 Query: 578 RPGXNQIE 601 P NQ+E Sbjct: 210 VPAVNQVE 217 >UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas mobilis|Rep: Putative oxidoreductase - Zymomonas mobilis Length = 273 Score = 98.7 bits (235), Expect = 9e-20 Identities = 61/175 (34%), Positives = 93/175 (53%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 + LNDG+++P + G + +++S+ V + GYR +DTAA Y++EE VG+G Sbjct: 7 VVLNDGHSMPAIGQGVYQLNPAQAESM------VALGYDLGYRAVDTAAWYENEEGVGEG 60 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 + A F+TTKL R AL +S++ LG+ ++LYLIH+P Sbjct: 61 LRSRHARS-------FITTKLMPQDMGRVNCFVALDKSIRNLGVTSLNLYLIHWP----- 108 Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 D Y ETWQ + R +G A SIGVSNF + ++++S + P NQIE Sbjct: 109 --GQDRKRYEETWQTLIQIRAIGKASSIGVSNFTIDHLDHIIADSGVVPAVNQIE 161 >UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteobacteria|Rep: Aldo/keto reductase - Shewanella sp. (strain ANA-3) Length = 280 Score = 98.7 bits (235), Expect = 9e-20 Identities = 60/160 (37%), Positives = 91/160 (56%), Gaps = 3/160 (1%) Frame = +2 Query: 95 NTIPIVA---LGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAE 265 N P+ A LGTG K++ + D AV A+E G RHIDTA +Y +E+ VG + Sbjct: 10 NQAPLTAMPMLGTGTFRLKDNAAFD----AVLMALEEGSRHIDTAQIYGNEQAVG----D 61 Query: 266 AIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDS 445 AI + REELF+TTK+W + +++ ++ +SL L Y+DL LIH+P+ + D Sbjct: 62 AINTSGIPREELFITTKVWTENLTKERFETSVIDSLTALQTKYLDLLLIHWPLNS---DE 118 Query: 446 PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVS 565 P ++YL + + D GL R IGVSNF Q+ + ++ Sbjct: 119 PSMVEYLSELKAVLDK---GLTRRIGVSNFTNAQLAQAIA 155 >UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase family; n=2; Streptococcus agalactiae|Rep: Oxidoreductase, aldo/keto reductase family - Streptococcus agalactiae H36B Length = 245 Score = 98.3 bits (234), Expect = 1e-19 Identities = 65/173 (37%), Positives = 98/173 (56%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262 LN+G IP + G G + D + E Q+V A++ GYR IDTA+ Y +EE VG+ Sbjct: 9 LNNGVKIPSL----GFGVFQIDDPL-ECEQSVLDALQVGYRLIDTASGYLNEEAVGR--- 60 Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 442 AI + R+E+FV TKLW + ++ PA+ +LK+L LDYI+LYLIH P+ Sbjct: 61 -AIKKSGIPRKEIFVVTKLWIQDASEEKAGPAIDRALKRLQLDYINLYLIHQPMG----- 114 Query: 443 SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 DY + ++ A + A +IGVSNF+ ++ L+ ++ I P NQI+ Sbjct: 115 -----DYYGACRALEKAYEERKALAIGVSNFSNGRVQDLILHNKIIPAVNQIQ 162 >UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 288 Score = 97.9 bits (233), Expect = 2e-19 Identities = 60/181 (33%), Positives = 101/181 (55%), Gaps = 4/181 (2%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P + LN+ +P++ LGT R +E + AV A++AGYR DTAAVY++E +G Sbjct: 6 PSVLLNNDIQMPLLGLGTFRLQGQE-----DTYSAVDAALKAGYRAFDTAAVYRNEAHLG 60 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP--- 421 + + ++RE++F+T+KL K + Q+SL++LGL YIDLYLIH+P Sbjct: 61 HALRCLLPKHGLSREDVFITSKL-GPKDQGSKARNGCQKSLEQLGLGYIDLYLIHWPGTQ 119 Query: 422 -IATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598 + +P+N ++W+ +++ G R+IGVSN+ + L+ + + P Q+ Sbjct: 120 GLPVGDKRNPEN--RAQSWRVLEEFYSEGKFRAIGVSNYTVEHMQELLKSCKVPPAVLQV 177 Query: 599 E 601 E Sbjct: 178 E 178 >UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteobacteria|Rep: Aldo/keto reductase - Mesorhizobium sp. (strain BNC1) Length = 274 Score = 97.5 bits (232), Expect = 2e-19 Identities = 63/170 (37%), Positives = 96/170 (56%) Frame = +2 Query: 92 GNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI 271 G TIP + G G + SD+ EV + + A+EAG+RH DTA +YQ+E +G+ + A Sbjct: 8 GATIPAL----GFGVFRMSDA--EVERIIPAALEAGFRHFDTAQIYQNEAALGRALERAG 61 Query: 272 ANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPD 451 A RE+LF+TTK+W D ++ D+ ++ ESL+KL +D +DL L+H+P P + Sbjct: 62 AR----REDLFLTTKVWVDNYSADKFAASVDESLEKLKVDQVDLLLLHWPAHEVPVAA-- 115 Query: 452 NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 +E ++DA G R IGVSN N Q+ ++ S NQ+E Sbjct: 116 ---QIERLNAVKDA---GKTRFIGVSNQNIAQMRESIARSAAPIVTNQVE 159 >UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini|Rep: Isoform 2 of Q96JD6 - Homo sapiens (Human) Length = 263 Score = 97.1 bits (231), Expect = 3e-19 Identities = 49/102 (48%), Positives = 64/102 (62%) Frame = +2 Query: 131 GTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 310 G + S +V +AV AI+AGYRH D A Y +E +VG GI I G V RE+LF+ Sbjct: 8 GLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIA 67 Query: 311 TKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 TKLW H + V A ++SLK L L+Y+DLYLIH+P+ KP Sbjct: 68 TKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109 >UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona intestinalis|Rep: Aldo-keto reductase 1a - Ciona intestinalis (Transparent sea squirt) Length = 584 Score = 97.1 bits (231), Expect = 3e-19 Identities = 66/180 (36%), Positives = 101/180 (56%), Gaps = 14/180 (7%) Frame = +2 Query: 65 QAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 244 + P ++LN G +P + LGT R +K +++ A++ GYR +DTA +Y E++ Sbjct: 256 EIPDVKLNSGYMMPPIGLGTARLFSKTYETVKT-------ALKLGYRMLDTAQIYTGEDK 308 Query: 245 VG-------QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDL 403 + + I AIA+ V R ELF+ TKL + ++ + ++ESLKKL DYIDL Sbjct: 309 INNFKVSSEEEIGRAIADSDVPRSELFIVTKLAPESMEKENAIAKVEESLKKLRTDYIDL 368 Query: 404 YLIH-FPIATK--PDDS--PD--NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 562 LIH F ++T PDD+ P+ N +L W+ M++ + GL RSIGVSN + LV Sbjct: 369 LLIHDFYMSTACGPDDTDLPECKNNPFL-AWKTMEEMQAKGLVRSIGVSNIYIEDLQYLV 427 >UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase family 1 member C-like protein 2 - Homo sapiens (Human) Length = 320 Score = 97.1 bits (231), Expect = 3e-19 Identities = 49/102 (48%), Positives = 64/102 (62%) Frame = +2 Query: 131 GTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 310 G + S +V +AV AI+AGYRH D A Y +E +VG GI I G V RE+LF+ Sbjct: 8 GLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIA 67 Query: 311 TKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 TKLW H + V A ++SLK L L+Y+DLYLIH+P+ KP Sbjct: 68 TKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109 >UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; Aspergillus terreus NIH2624|Rep: Putative uncharacterized protein - Aspergillus terreus (strain NIH 2624) Length = 301 Score = 96.7 bits (230), Expect = 4e-19 Identities = 74/207 (35%), Positives = 100/207 (48%), Gaps = 33/207 (15%) Frame = +2 Query: 80 QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259 +L+ G +P V LGT E V AV A+ GYRHID AA Y +E +VG G Sbjct: 8 KLSSGYDMPAVGLGTWLSKPHE------VENAVETALRLGYRHIDAAACYLNENEVGNGW 61 Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYL---------- 409 ++ G V R+++F+T+KLWN H D V A+ ++LK L DY+DLYL Sbjct: 62 KKS---G-VPRDQIFITSKLWNTHHHPDHVEEAVNKTLKDLQTDYLDLYLVFPSLLVLIH 117 Query: 410 ----------IHFPIATK-------PDDSPD------NIDYLETWQGMQDARQLGLARSI 520 IH+P+A + P D NI +TW ++ G RSI Sbjct: 118 DLLSLLTNNKIHWPVAFEHTNETLTPIDPVSKRFRLANIPIADTWAALEKLVDAGKVRSI 177 Query: 521 GVSNFNATQITRLVSNSYIRPGXNQIE 601 GVSNF +I L+ + I P NQIE Sbjct: 178 GVSNFTIEKIEELLKTARIPPAVNQIE 204 >UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus niger|Rep: Putative frameshift - Aspergillus niger Length = 357 Score = 96.7 bits (230), Expect = 4e-19 Identities = 71/185 (38%), Positives = 104/185 (56%), Gaps = 12/185 (6%) Frame = +2 Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262 LN G IP ALG G T ++ DS +E V ++ G R IDTA VY E+QVG+GI Sbjct: 40 LNTGAKIP--ALGVG--TFQDPDSQEET---VCQVLQRGMRLIDTARVYGVEQQVGRGIK 92 Query: 263 EAIANGLVTREELFVTTKLW-NDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK-- 433 ++ G V REE+F+ TKLW ND H D V A+ +SL+ L Y+DL L+H+P K Sbjct: 93 KS---G-VPREEIFLGTKLWCNDFHP-DDVERAVDDSLRDLYTPYVDLLLMHYPCTFKRG 147 Query: 434 ----PDDSPDNI-----DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPG 586 P D+ + +++TW+ ++ + G R+IGVSNF+ +I L+ + P Sbjct: 148 EDRFPRDAEGRMIHGETTFVDTWRALEKVVKTGKVRAIGVSNFSKGEIETLLRETSTVPA 207 Query: 587 XNQIE 601 +Q+E Sbjct: 208 VHQME 212 >UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: Oxidoreductase - Bradyrhizobium japonicum Length = 272 Score = 96.3 bits (229), Expect = 5e-19 Identities = 62/171 (36%), Positives = 94/171 (54%) Frame = +2 Query: 89 DGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEA 268 +G IP + LGT + + + E A+ GYRHIDTA VY +E +VG G+ Sbjct: 7 NGARIPAIGLGTWELSGRPCARVVEQ------ALRLGYRHIDTAQVYDNEREVGDGVR-- 58 Query: 269 IANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSP 448 A+G V R+++F+TTK+W + A + + +++ESL +L L +DL L+H+P Sbjct: 59 -ASG-VRRDDVFLTTKVWTNHFAPNDLERSVKESLARLRLPSVDLLLLHWP--------N 108 Query: 449 DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 ++ ET + ARQ+GL R IGVSNF I + V+ S NQ+E Sbjct: 109 SHVPLAETLGALSHARQMGLTRHIGVSNFTVALIEQAVALSPEPLVCNQVE 159 >UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto reductase family - Caulobacter crescentus (Caulobacter vibrioides) Length = 279 Score = 95.9 bits (228), Expect = 7e-19 Identities = 62/182 (34%), Positives = 98/182 (53%) Frame = +2 Query: 56 MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 235 M+ P ++ D + + ALG G + ++ V +A +E GYRHIDTA +Y + Sbjct: 1 MSKLVPAVRSGD---VLMPALGFGTWQLENGTAVPLVEKA----LEIGYRHIDTAQIYGN 53 Query: 236 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 415 E VG AI N V R+E+F+TTK+W D+ A + + ++SL+KLG+D +DL L+H Sbjct: 54 ERDVGA----AIRNSGVKRDEIFLTTKVWIDQFADGDLQRSAEKSLEKLGVDQVDLLLLH 109 Query: 416 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQ 595 +P KP+ + ET + + R G R+IG+SNF + Q+ S +Q Sbjct: 110 WP---KPE-----VPLAETLKALNAVRAKGWTRAIGLSNFPSAQLEEAAKLSEAPIATDQ 161 Query: 596 IE 601 +E Sbjct: 162 VE 163 >UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis alexandrii HTCC2633 Length = 275 Score = 95.9 bits (228), Expect = 7e-19 Identities = 58/159 (36%), Positives = 87/159 (54%) Frame = +2 Query: 125 GRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 304 G GT + D ++ + V A++ GYRHIDTA +Y +E VG G ++ G V RE+ F Sbjct: 16 GFGTWQLED--EDAARGVATALKTGYRHIDTAQIYGNEAAVGDGWKQS---G-VKREDFF 69 Query: 305 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 484 +TTK+W DK + +++ESL KL DY+DL L+H+P+ P ET + M Sbjct: 70 LTTKVWRDKFRDGDLQASVKESLDKLKTDYVDLLLLHWPVPEVP--------IAETMKAM 121 Query: 485 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 + ++ G R IGVSNF + ++S NQ+E Sbjct: 122 NEVKEAGQVRHIGVSNFTVDLLDEARAHSGAPLVANQVE 160 >UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family; n=1; Haloarcula marismortui|Rep: Oxidoreductase aldo/keto reductase family - Haloarcula marismortui (Halobacterium marismortui) Length = 274 Score = 95.9 bits (228), Expect = 7e-19 Identities = 62/155 (40%), Positives = 84/155 (54%) Frame = +2 Query: 92 GNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI 271 G ++P + LGT + T + R+ V A+ GYRHIDTA Y +E QVG G+ A Sbjct: 8 GTSVPALGLGTWQLTGQSC------RETVETALGMGYRHIDTAQAYGNERQVGLGMDAAA 61 Query: 272 ANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPD 451 V RE++F+TTKL V + +ESL KLG DY+DL LIH+P ++P Sbjct: 62 ----VDREDVFLTTKLDGSNRDERSVRRSTRESLNKLGTDYLDLLLIHWP------NTPW 111 Query: 452 NIDYLETWQGMQDARQLGLARSIGVSNFNATQITR 556 ET M D + GL R IGVSNF+ + + R Sbjct: 112 MASLSETLGAMNDVVEEGLVRHIGVSNFSPSLLDR 146 >UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15; Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B - Bradyrhizobium sp. (strain ORS278) Length = 273 Score = 95.1 bits (226), Expect = 1e-18 Identities = 59/159 (37%), Positives = 87/159 (54%) Frame = +2 Query: 125 GRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 304 G GT + ++ R AV A+ GYRHIDTA +Y +E+ +G +A A + RE+L Sbjct: 15 GLGTFRMQGTV--CRDAVESALALGYRHIDTAEMYANEDAIGAALAAA----QIAREDLH 68 Query: 305 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 484 VTTK+W + A D + A SLKKL LD++DLYLIH+P AT ++ + + Sbjct: 69 VTTKVWPENLAPDAIRRAFDTSLKKLRLDFVDLYLIHWP-AT-------GMNLPAAMETL 120 Query: 485 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 +Q G R+IGV+NF + + V + NQ+E Sbjct: 121 MALKQEGRTRAIGVANFTVALLKQAVEDIQAPVACNQVE 159 >UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetrans|Rep: Oxidoreductase - Mycoplasma penetrans Length = 285 Score = 94.7 bits (225), Expect = 2e-18 Identities = 57/175 (32%), Positives = 96/175 (54%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 I+L +G +PI+ LG + + ++ + +A+ + GYR IDTA VY +EE VG Sbjct: 4 IKLANGLHMPIIGLGVYKAEGENCENT--IIKAID---DYGYRMIDTAQVYFNEEFVGNA 58 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 I + + RE++F+TTK+W + + + ++ +SLKKL +YIDL L+H P Sbjct: 59 IKQT----KIKREDIFITTKVWISNYGYNNTMYSISKSLKKLQTNYIDLVLLHQPFG--- 111 Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 DY W+ ++ + G+ ++IGVSNF A ++ + ++P NQIE Sbjct: 112 -------DYYSAWKALEVLYKKGIVKAIGVSNFEADRLVDFCLHVDVKPVINQIE 159 >UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; Helicobacter hepaticus|Rep: Putative uncharacterized protein - Helicobacter hepaticus Length = 270 Score = 94.7 bits (225), Expect = 2e-18 Identities = 61/175 (34%), Positives = 92/175 (52%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 + LN+G +PI+ LGT T K ++A+ AIE GYR D+A +Y +E ++G Sbjct: 4 LTLNNGVKMPILGLGTYSLTGKAG------QKAMSEAIEVGYRLFDSAQMYNNEAELGAA 57 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 I A+ G + REE F+ TKL + + D ++++SLK LGLDYID LIH P + Sbjct: 58 INAAVKGG-IKREEFFIQTKLL-ESSSEDLAKKSIEKSLKTLGLDYIDSLLIHMPYSQSK 115 Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 ++ M+ + G+ R IG+SNF A + V + + P NQ E Sbjct: 116 ----------AMYRAMESFYKQGILRVIGISNFGAKAYSEFVKSCEVIPAINQCE 160 >UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reductase; n=4; Saccharomycetales|Rep: NADPH-dependent alpha-keto amide reductase - Saccharomyces cerevisiae (Baker's yeast) Length = 312 Score = 94.3 bits (224), Expect = 2e-18 Identities = 63/179 (35%), Positives = 93/179 (51%), Gaps = 6/179 (3%) Frame = +2 Query: 83 LNDGNTIPIVAL-GTGRGTAK--ESD---SIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 244 LN+GN IP +A+ GTG K E+D S V Q VY G HID A +Y+ + Sbjct: 10 LNNGNKIPAIAIIGTGTRWYKNEETDATFSNSLVEQIVYALKLPGIIHIDAAEIYRTYPE 69 Query: 245 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424 VG+ A++ R +F+T K D L +LKK+G DY+DLYL+H P Sbjct: 70 VGK----ALSLTEKPRNAIFLTDKYSPQIKMSDSPADGLDLALKKMGTDYVDLYLLHSPF 125 Query: 425 ATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 +K + + E W+ M+ + G A++IGVSNF + R++ + ++P NQIE Sbjct: 126 VSK---EVNGLSLEEAWKDMEQLYKSGKAKNIGVSNFAVEDLQRILKVAEVKPQVNQIE 181 >UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1; Saccharopolyspora erythraea NRRL 2338|Rep: 2,5-diketo-D-gluconic acid reductase - Saccharopolyspora erythraea (strain NRRL 23338) Length = 159 Score = 93.9 bits (223), Expect = 3e-18 Identities = 57/117 (48%), Positives = 71/117 (60%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P + LN+G +P LG G E DE AV A+EAGYR IDTAA Y +E VG Sbjct: 5 PTVTLNNGVEMP--QLGYGVFQVPE----DETAAAVGAALEAGYRSIDTAAAYGNEAAVG 58 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 421 + +A +GL R+ELFVTTKLWN D + A SL+ LGLD++DLYLIH+P Sbjct: 59 RALA---GSGLA-RDELFVTTKLWNADQGYDNALRAFDTSLELLGLDHLDLYLIHWP 111 >UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7; Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 - Arabidopsis thaliana (Mouse-ear cress) Length = 349 Score = 93.9 bits (223), Expect = 3e-18 Identities = 70/207 (33%), Positives = 113/207 (54%), Gaps = 33/207 (15%) Frame = +2 Query: 80 QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259 +L G+ IP V LGT R ++ + ++ V +E GYRHIDTA Y D+ +VGQGI Sbjct: 17 RLLSGHKIPAVGLGTWRSGSQAAHAV------VTAIVEGGYRHIDTAWEYGDQREVGQGI 70 Query: 260 AEAIANGL---------------VTREELFVTTKLWN-----------DKHARDQVVPAL 361 A+ GL + R+ + +++ L N + + ++V PAL Sbjct: 71 KRAMHAGLERRDLFVTSKLWYTLILRKMINLSSPLMNVLVGTCLNKRCTELSPERVRPAL 130 Query: 362 QESLKKLGLDYIDLYLIHFPI-----ATKPDDSPDNIDY-LE-TWQGMQDARQLGLARSI 520 Q +LK+L L+Y+DLYLIH+PI A+KP + D +D+ +E W+ M++ + L R+I Sbjct: 131 QNTLKELQLEYLDLYLIHWPIRLREGASKPPKAGDVLDFDMEGVWREMENLSKDSLVRNI 190 Query: 521 GVSNFNATQITRLVSNSYIRPGXNQIE 601 GV NF T++ +L+ + + P Q+E Sbjct: 191 GVCNFTVTKLNKLLGFAELIPAVCQME 217 >UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter cryohalolentis K5|Rep: Aldo/keto reductase - Psychrobacter cryohalolentis (strain K5) Length = 282 Score = 93.5 bits (222), Expect = 4e-18 Identities = 62/169 (36%), Positives = 94/169 (55%), Gaps = 2/169 (1%) Frame = +2 Query: 101 IPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANG 280 IP++ LGT + T + D ID V Q + GY HIDTA Y +E +VG+GI + +G Sbjct: 16 IPVLGLGTWQSTGQ--DCIDVVSQG----LRMGYEHIDTAQAYGNEVEVGKGIKQ---SG 66 Query: 281 LVTREELFVTTKLWND--KHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDN 454 V R++ F+TTK++ D K +++V A + SL+ L DY+DL L+H+P D Sbjct: 67 -VARDKFFLTTKIFPDDMKFEPEKLVAAAKRSLENLDTDYVDLLLLHWP--------DDR 117 Query: 455 IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 + ET + + ++ GL R+IGVSNFN I + + NQ+E Sbjct: 118 VPLSETIPALCELQKQGLTRNIGVSNFNIANIIEAKRYADVPIVVNQVE 166 >UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 264 Score = 93.5 bits (222), Expect = 4e-18 Identities = 61/175 (34%), Positives = 93/175 (53%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 + LNDG +P+ LG R E+ D +A++ GYR +DTA +YQ+E++VG Sbjct: 13 VTLNDGRKMPLFGLGVFR---LETGCED----VCLFALKNGYRMLDTADIYQNEKEVGSA 65 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 + ++ GL RE+++VTTKL + + +ES+KKL + Y+DL+LIH P Sbjct: 66 VRKS---GL-KREDIYVTTKLKPSEEGHSNALKYAKESIKKLDIGYVDLFLIHTP----- 116 Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 P NI + + + ++ GL RS+GVSNF + L P NQIE Sbjct: 117 --RPGNI--IAAYDALLTLKEEGLIRSVGVSNFGVHHLEELRKAGCRTPAINQIE 167 >UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Rep: ABL209Cp - Ashbya gossypii (Yeast) (Eremothecium gossypii) Length = 310 Score = 93.5 bits (222), Expect = 4e-18 Identities = 63/178 (35%), Positives = 95/178 (53%), Gaps = 4/178 (2%) Frame = +2 Query: 80 QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259 +L+DG IP V LG + + + V+ VY A+E GYR D+A Y +E+ V +GI Sbjct: 14 RLSDGTQIPSVGLGVYQVSEQT------VQDLVYEALEVGYRLFDSAQAYHNEDGVARGI 67 Query: 260 AEAIANGL-VTREELFVTTKLWNDKHARDQVVPALQESLKKLG-LDYIDLYLIHFPIATK 433 A + + RE+++ TTK+ H + +L++SL G L YIDL L+H P++ Sbjct: 68 AAWLKHAPGRRREDVYFTTKINTQNHGYEATKKSLEKSLHAAGPLGYIDLVLVHAPMS-- 125 Query: 434 PDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV--SNSYIRPGXNQIE 601 D L TWQ +++A G RSIGVSN+ ++ L+ IRP NQ+E Sbjct: 126 -----DRTRRLGTWQALEEAVVEGQVRSIGVSNYGQQHLSELLGWEGLKIRPVVNQVE 178 >UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 289 Score = 93.5 bits (222), Expect = 4e-18 Identities = 62/177 (35%), Positives = 92/177 (51%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P ++L DGN IP+ G + ++ +AV IE G+ H+D A +Y EE+V Sbjct: 4 PLLRLRDGNQIPL-----DLGDTTFGQGLVDLTKAV---IEKGFYHLDCAEMYGTEEEV- 54 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430 A AI V RE+LF+T K+ D + A+ +SL+K+ +Y DLYLIH P Sbjct: 55 ---AIAIKESGVPREKLFITNKV---AQGIDDIEAAIDQSLQKMQTNYFDLYLIHIPFFA 108 Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 K ++ D+ W+ M+ ++ G ARSIGVSN+ I + + P NQIE Sbjct: 109 KSEE-----DFQRAWKTMEGIQKAGKARSIGVSNYMRPHIEATLKGATSPPVTNQIE 160 >UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum lacusprofundi ATCC 49239|Rep: Aldo/keto reductase - Halorubrum lacusprofundi ATCC 49239 Length = 309 Score = 93.5 bits (222), Expect = 4e-18 Identities = 65/181 (35%), Positives = 99/181 (54%), Gaps = 1/181 (0%) Frame = +2 Query: 62 VQAPCIQLNDGNTIPIVALGTGRGTAKESDSI-DEVRQAVYWAIEAGYRHIDTAAVYQDE 238 V P L G+T+P + LGT A + D I D VR A + +GY HIDTA Y +E Sbjct: 32 VTIPTQTLPSGDTLPALGLGT---YALDDDQIADSVRAA----LSSGYTHIDTAEGYHNE 84 Query: 239 EQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 418 E +G+ +AE R+++F+T+K+ + ++ + + SL++L DY+DLYLIH+ Sbjct: 85 EAIGEVLAE------YDRDDVFLTSKVLAKNLGYESLIQSCEASLERLETDYLDLYLIHW 138 Query: 419 PIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598 P +P I E+ Q M + GL R++GVSNF+A Q++ S + NQI Sbjct: 139 P-------NP-AISLRESLQAMAELHDRGLVRNVGVSNFSAYQLSCANHISEVPIAVNQI 190 Query: 599 E 601 E Sbjct: 191 E 191 >UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. precursor; n=1; Aspergillus niger|Rep: Contig An01c0460, complete genome. precursor - Aspergillus niger Length = 351 Score = 92.3 bits (219), Expect = 8e-18 Identities = 70/189 (37%), Positives = 92/189 (48%), Gaps = 21/189 (11%) Frame = +2 Query: 98 TIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIAN 277 T P V LGT +G A V++AV A+ GYRHIDTA Y +E +VG EAI Sbjct: 45 TFPAVGLGTFQGDAGNRG----VKEAVLQALRCGYRHIDTATAYGNEIEVG----EAIKE 96 Query: 278 GLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDY-IDLYLIHFPIATKP---DDS 445 + REE+ VTTKL H V AL SL++L L+Y + ++L + P Sbjct: 97 SRIPREEIIVTTKLAQTWHRVSDVERALDLSLERLQLNYGLSMHLYSASSYSVPHAYSPG 156 Query: 446 PDN-----------------IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 574 PDN DY TW M+ G + IGVSNFN ++ RL+ ++ Sbjct: 157 PDNNTIRHPNGKPIIDHELSRDYPSTWAAMESLVDKGKLKMIGVSNFNILKLERLLGSAR 216 Query: 575 IRPGXNQIE 601 I P NQIE Sbjct: 217 IPPAVNQIE 225 >UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG6084-PA, isoform A - Tribolium castaneum Length = 493 Score = 91.1 bits (216), Expect = 2e-17 Identities = 59/177 (33%), Positives = 97/177 (54%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P +LN+G IP+ G A D + + V + + YR +D +++++E++ G Sbjct: 9 PIAKLNNGIEIPVF------GLAAPQDFFEV--ENVQLVVSSNYRLMD-CSIFENEKRFG 59 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430 + + I G + R++LF+ +K + + V AL ++LKKL + Y+DLYLI P A Sbjct: 60 VALQQLIEGGKIRRKDLFLMSKFCCT-NTTNLVKAALLDTLKKLQVAYLDLYLIERPPAC 118 Query: 431 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 K + +ETW+ M+ L R+IG+SNFN+ QI R++ N IRP NQI+ Sbjct: 119 KDHN------LIETWEAMEGLYSEKLTRAIGLSNFNSKQIERILENCTIRPQVNQIQ 169 Score = 77.0 bits (181), Expect = 3e-13 Identities = 39/91 (42%), Positives = 57/91 (62%), Gaps = 12/91 (13%) Frame = +2 Query: 365 ESLKKLGLDYIDLYLIHFPIATKPDDS------------PDNIDYLETWQGMQDARQLGL 508 ESLK L LDY+D+YL+H+P A K S P ++D+++TW+ M+ + L Sbjct: 271 ESLKNLQLDYLDVYLMHWPHALKEGPSLHPIDPKTGLFIPSDVDFVDTWKAMEKMHEKDL 330 Query: 509 ARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 +SIG+SNFN+ QI RL+ ++ I P NQIE Sbjct: 331 TKSIGISNFNSNQIDRLLKSAKIAPVINQIE 361 >UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; Vanderwaltozyma polyspora DSM 70294|Rep: Putative uncharacterized protein - Vanderwaltozyma polyspora DSM 70294 Length = 313 Score = 91.1 bits (216), Expect = 2e-17 Identities = 61/188 (32%), Positives = 94/188 (50%), Gaps = 6/188 (3%) Frame = +2 Query: 56 MAVQAPCIQLNDGNTIPIVAL-GTGRGTAKESDS----IDEVRQAVYWAIEA-GYRHIDT 217 M++ LN+GN IP +++ GTG K S DE+ + + +A+ G HID Sbjct: 1 MSLTQKFFDLNNGNQIPSISIIGTGTRWFKRPGSEHTFSDELVEQIKYALSLPGIIHIDA 60 Query: 218 AAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYI 397 A Y + +A+A+ R E+F+T K + + L LK LGLDY+ Sbjct: 61 AECYGTYPE----LAKALKESSKPRSEIFITDKYSTQTKFTNDPIEGLNTGLKTLGLDYV 116 Query: 398 DLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 577 DLYLIH P + ++ + W+ M+ + G A+SIGVSNF+ I ++ + I Sbjct: 117 DLYLIHSPFF--DPEFKGSLTLEKVWKDMETLYKEGKAKSIGVSNFSVKNIEEILKIAGI 174 Query: 578 RPGXNQIE 601 +P NQIE Sbjct: 175 KPQVNQIE 182 >UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; Pichia guilliermondii|Rep: Putative uncharacterized protein - Pichia guilliermondii (Yeast) (Candida guilliermondii) Length = 287 Score = 91.1 bits (216), Expect = 2e-17 Identities = 64/180 (35%), Positives = 93/180 (51%), Gaps = 4/180 (2%) Frame = +2 Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253 C L +G+ IP +G A ++ I E A++ GYR IDTA Y++E + G+ Sbjct: 9 CFPLLNGSRIPACGVGVYLLPASQTAGIVEK------ALDVGYRLIDTAQEYENERETGE 62 Query: 254 GIAEAIANGLVT-REELFVTTKLWNDKHARDQVVPALQESLKKLG-LDYIDLYLIHFPIA 427 GI + RE++ TTK+ N D+ +L+ESL K+ L+YIDL LIH P++ Sbjct: 63 GIKAWLGKDKNNKREDVLYTTKITNLNQGYDRTWRSLKESLNKVKHLEYIDLVLIHDPLS 122 Query: 428 TKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV--SNSYIRPGXNQIE 601 K +ETW+ +Q+A G+ +SIGVSNF I L +P NQIE Sbjct: 123 DKKTR-------IETWKALQEAVDSGMVKSIGVSNFGKHHIQELYDWEGLKYKPIVNQIE 175 >UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 301 Score = 90.6 bits (215), Expect = 2e-17 Identities = 57/179 (31%), Positives = 95/179 (53%), Gaps = 5/179 (2%) Frame = +2 Query: 80 QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259 + +DG +P + LG R + +D +A A+++GYR DTA +Y++E +G + Sbjct: 13 KFSDGYEMPKIGLGISR--IETQQDLDVSIEA---ALKSGYRQFDTANLYKNETFLGNSL 67 Query: 260 AEAIANGLVTREELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFP---IA 427 + + +TRE++F+TTK+ +++ ++ L SL L DY+DL LIH+P Sbjct: 68 KKYLPQFGLTREDVFITTKVRTLNENTVEETEKQLANSLATLQTDYVDLLLIHYPRDRDT 127 Query: 428 TKPDDSPDNIDYLE-TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 DD N + WQ ++ A++ G RSIGVSN+ + + + IRP NQ E Sbjct: 128 GNDDDYEINKSRRKIVWQTLEKAKESGRVRSIGVSNYEVYHLVEMFEYAKIRPVLNQYE 186 >UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 287 Score = 90.6 bits (215), Expect = 2e-17 Identities = 56/178 (31%), Positives = 94/178 (52%), Gaps = 4/178 (2%) Frame = +2 Query: 80 QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259 +L +G IP +ALGT D++ AV A++ GYR DTA Y++E+ +G + Sbjct: 3 KLKNGQEIPKLALGTYEAKG------DQLFAAVDEALKVGYRSFDTAKYYENEKDLGLAL 56 Query: 260 AEAIANGLVTREELFVTTKL--WNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433 + + E++++T+K+ ++ K+A + + + ESL+ L Y+DL L+H+P Sbjct: 57 KTLLPRHNICSEDIYLTSKVFPYSSKNAAELIRKDVNESLELLDRKYLDLVLVHYPRPLD 116 Query: 434 PDDSPDN--IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 +D +N + +TW ++ G RSIGVSN+ I + S I P NQIE Sbjct: 117 TEDLNENNKMYRKDTWIALEKLHAEGKIRSIGVSNYEPHHIEEMRSYITIEPQVNQIE 174 >UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 282 Score = 89.8 bits (213), Expect = 4e-17 Identities = 62/175 (35%), Positives = 95/175 (54%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 I LN+G TIP V LGT E D + + AV +A++ Y IDTA VY +E VG+G Sbjct: 4 ITLNNGITIPQVGLGT---YLLEPD---DAQSAVTYALDNDYTLIDTANVYVNERAVGRG 57 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 + + R+E+F+ TKLW R A++E+L++LG DYIDL ++H P Sbjct: 58 MRASSK----ARDEIFLETKLWPSFFER---ASAVEETLERLGTDYIDLMILHQPAG--- 107 Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 D + ++ ++ A + G R+IG+SNF+ Q R++ + P NQ+E Sbjct: 108 -------DTVAGYRILEKAHKEGKIRAIGLSNFDVAQTQRILDECEVVPTINQVE 155 >UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; Vitis vinifera|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 212 Score = 89.4 bits (212), Expect = 6e-17 Identities = 60/177 (33%), Positives = 94/177 (53%), Gaps = 9/177 (5%) Frame = +2 Query: 92 GNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI 271 G IP+V + T S+++ + ++ AIE GYRH D A Y E+ +G+ I +A+ Sbjct: 7 GKAIPLVGMVTTVYPFAPSETMID---SILTAIELGYRHFDCVAAYLSEKPLGEAIKKAV 63 Query: 272 ANGLV-TREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD--D 442 GL+ +R+ELF+T + N L LDY+DLYLIH+ ++ KP + Sbjct: 64 KLGLIKSRDELFITLQALN------------------LQLDYLDLYLIHWSVSLKPGNYE 105 Query: 443 SPDN------IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQ 595 P N ID W+ M+D ++L L ++IGVSNF+ ++ L+ + I P NQ Sbjct: 106 LPVNKDDHLPIDLGSVWKAMEDFQKLSLTKAIGVSNFSCNKLEELLQTASILPAVNQ 162 >UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto reductase family - Thermotoga maritima Length = 274 Score = 89.0 bits (211), Expect = 8e-17 Identities = 61/166 (36%), Positives = 90/166 (54%), Gaps = 6/166 (3%) Frame = +2 Query: 92 GNTIPIVALGT-GRGTAKESDSI--DEVRQAVYWAIEAGYRHIDTAAVY---QDEEQVGQ 253 G IP + LGT G G + D +E+ + + AI+ GY HIDTA Y EE +G+ Sbjct: 10 GEEIPALGLGTWGIGGFETPDYSRDEEMVELLKTAIKMGYTHIDTAEYYGGGHTEELIGK 69 Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433 I + RE+LF+ +K+W RD ++ +L+ +LK+L DY+DLYLIH+P Sbjct: 70 AIKD------FRREDLFIVSKVWPTHLRRDDLLRSLENTLKRLDTDYVDLYLIHWP---- 119 Query: 434 PDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 571 +P+ I ET M + + GL R IGVSNF+ + +S S Sbjct: 120 ---NPE-IPLEETLSAMAEGVRQGLIRYIGVSNFDRRLLEEAISKS 161 >UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=5; Lactobacillus|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 282 Score = 89.0 bits (211), Expect = 8e-17 Identities = 58/174 (33%), Positives = 94/174 (54%) Frame = +2 Query: 80 QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 259 +L DG +P++ G GT +D + A+ A +AGYR DTA +Y++E+ +G I Sbjct: 11 KLADGRQMPVM----GFGTYLLNDQ-PTMNTAIQTAWDAGYRMFDTAMLYRNEDILGPAI 65 Query: 260 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 439 + GL RE LF+T+K+ DQ + A++ SLK+L DY+DL LIH+P+ Sbjct: 66 QQL---GL-PREGLFLTSKVAEIVQGYDQTMKAVEGSLKRLQTDYLDLLLIHWPVRE--- 118 Query: 440 DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 + +TW+ ++ + G +SIGVSN+ + L + + P NQ+E Sbjct: 119 ------HFFDTWRALEQLKADGQVKSIGVSNYTIAHLELLATKAKEMPVVNQVE 166 >UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; Coccidioides immitis|Rep: Putative uncharacterized protein - Coccidioides immitis Length = 324 Score = 89.0 bits (211), Expect = 8e-17 Identities = 63/170 (37%), Positives = 89/170 (52%), Gaps = 11/170 (6%) Frame = +2 Query: 125 GRGTAKESDSI---DEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTRE 295 G GT + S+ V+ +V A++ GYRHID A Y V +GI AI V RE Sbjct: 20 GLGTFQVDPSLYPEGSVKDSVLHALKIGYRHIDAALAY-GWGSVERGIGAAIRASGVPRE 78 Query: 296 ELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLI---HFPIATKPDDSP-DNID- 460 ++FV TKL N HA + V + SLK LGL Y+ ++ KPD P +I+ Sbjct: 79 DVFVVTKLHNCFHAPEDVEVGMNMSLKNLGLGYVPYAYTKGENYSTVRKPDGKPVVDIEL 138 Query: 461 ---YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 + TW+ M++ G A+ IGVSNF+ ++ RL+S I P NQ+E Sbjct: 139 SRAFDTTWKAMENLVDQGKAKLIGVSNFSTPKLKRLLSVCRIFPVVNQVE 188 >UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 293 Score = 88.6 bits (210), Expect = 1e-16 Identities = 58/150 (38%), Positives = 82/150 (54%), Gaps = 3/150 (2%) Frame = +2 Query: 161 EVRQAVYWAIE-AGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLW-NDKH 334 E +QA+ A + AGYRH+DTA Y++E G+ + E V R ELF TTK++ N+ Sbjct: 41 ECKQALLNAFDKAGYRHVDTARYYRNEADCGEAVRECS----VPRSELFYTTKVYLNEMG 96 Query: 335 ARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLAR 514 + A+++SL K GLDY+DL L+H P K L++W + + Q G R Sbjct: 97 GGSKTRLAVEDSLAKAGLDYLDLVLLHAPDGGKK-------FRLDSWDTLTELVQEGKVR 149 Query: 515 SIGVSNFNATQITRLV-SNSYIRPGXNQIE 601 S+GVSNF I L+ S + P NQIE Sbjct: 150 SLGVSNFGPHHIQELIDSKPKVLPVCNQIE 179 >UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriaceae|Rep: Aldehyde reductase - Haloarcula marismortui (Halobacterium marismortui) Length = 279 Score = 88.6 bits (210), Expect = 1e-16 Identities = 52/137 (37%), Positives = 77/137 (56%) Frame = +2 Query: 125 GRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 304 G GT + D+ ++ ++V A+EAGYRHIDTA Y +E VG GIA A V R+++F Sbjct: 21 GLGTWQNEDA-EQCAESVRTALEAGYRHIDTAQAYDNESAVGDGIAAAD----VDRDDIF 75 Query: 305 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 484 + TK+W + D V+ +ESL KLG+D +DL +H+ + P+ ET Sbjct: 76 LATKVWISNLSHDDVIETTEESLDKLGVDSVDLLYVHWAAG---EYEPE-----ETLPAF 127 Query: 485 QDARQLGLARSIGVSNF 535 + GL ++GVSNF Sbjct: 128 DELVDRGLIDNVGVSNF 144 >UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; Caenorhabditis|Rep: Probable oxidoreductase ZK1290.5 - Caenorhabditis elegans Length = 321 Score = 88.6 bits (210), Expect = 1e-16 Identities = 62/178 (34%), Positives = 94/178 (52%), Gaps = 1/178 (0%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P L++ +P++ LGT D++ ++ + GYR IDTA Y E+Q+G Sbjct: 3 PTTVLSNNVEMPLIGLGTTHSGGYYHDAV------LHSIKKCGYRLIDTAKRYGVEKQLG 56 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430 A+ N V REE+F++TKLW D+V A Q S +KL DY+D+Y+IH P Sbjct: 57 I----AVKNCSVPREEMFLSTKLW-PVDCGDEVYNAFQTSCEKLQTDYLDMYMIHMP--Q 109 Query: 431 KPDDSPDNIDYLE-TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 PD + + E TW+ M+ + RSIGVSN++ + L+ + I P NQ+E Sbjct: 110 LPDWIVNQKETKEKTWRQMELLYEDEHVRSIGVSNYSIEDLDELLEFASILPHANQVE 167 >UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasidiella neoformans|Rep: Oxidoreductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 321 Score = 88.2 bits (209), Expect = 1e-16 Identities = 71/189 (37%), Positives = 104/189 (55%), Gaps = 15/189 (7%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAA---VYQDEEQV 247 I LNDG+ IP +A GT + KE +V QA I+ G+ HIDTA VY +EE+V Sbjct: 6 ITLNDGHRIPAIAFGTWK-IPKEVTPF-QVGQA----IDVGFDHIDTAQGRIVYHNEEEV 59 Query: 248 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427 GQ I E+ GL +R +L+VTTK W+ + ++ ESL+KLGL+Y+DLYLIH P Sbjct: 60 GQAIKES---GL-SRNQLWVTTK-WSGIDGKG-ARQSIGESLEKLGLEYLDLYLIHSPQV 113 Query: 428 TKPDDSPDNIDYLETWQGMQDARQLGLARSIGVS------------NFNATQITRLVSNS 571 TK D LET Q + +G+++ + +FN Q+ L++++ Sbjct: 114 TK-GDIKGAWKELETLQKEGKTKSIGVSKQVYYQTIFFASLSDVWDSFNKEQLQELLAHA 172 Query: 572 YIRPGXNQI 598 ++P NQI Sbjct: 173 TVKPVVNQI 181 >UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Schizosaccharomyces pombe|Rep: Xylose and arabinose reductase - Schizosaccharomyces pombe (Fission yeast) Length = 275 Score = 88.2 bits (209), Expect = 1e-16 Identities = 52/144 (36%), Positives = 80/144 (55%), Gaps = 1/144 (0%) Frame = +2 Query: 173 AVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVV 352 +VY A++ GYRHID+A +Y +E G+ I + + RE+++ T+KL ND + Sbjct: 32 SVYAALQCGYRHIDSAQMYHNEADCGRAILKFMEETGTKREDIWFTSKL-NDLSGYKSTL 90 Query: 353 PALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSN 532 ++ S+K GL YIDL+L+H P D +E+W+ ++ + G R+IGVSN Sbjct: 91 SSIDASVKACGLGYIDLFLLHSPYG----------DRIESWKALEKGVEEGKLRAIGVSN 140 Query: 533 FNATQITRLV-SNSYIRPGXNQIE 601 F I L+ S+ I P NQIE Sbjct: 141 FGPHHIQELLDSHPKIIPCVNQIE 164 >UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetrans|Rep: Oxidoreductase - Mycoplasma penetrans Length = 289 Score = 87.8 bits (208), Expect = 2e-16 Identities = 65/175 (37%), Positives = 91/175 (52%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 I LN+GN IP + G + KE E V AI GYR IDTA Y +E++ G G Sbjct: 9 ITLNNGNKIPSIGFGVFQ-IPKE-----ETADCVKKAISIGYRLIDTAQAYHNEKETGLG 62 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 I +G V REE+F+TTK+W + R ++ ESLK+L Y+DL L+H P Sbjct: 63 IK---LSG-VKREEIFLTTKVWVSNYER--CYESVIESLKRLDTSYLDLILLHQPFG--- 113 Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 +Y + +Q ++ + R+IGVSNF +I L + I+P NQIE Sbjct: 114 -------NYYKAYQDLERLYKENKVRNIGVSNFWDNRIIDLCFFNQIKPMVNQIE 161 >UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina baltica OS145|Rep: Aldo/keto reductase - Idiomarina baltica OS145 Length = 263 Score = 87.8 bits (208), Expect = 2e-16 Identities = 54/136 (39%), Positives = 77/136 (56%) Frame = +2 Query: 161 EVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR 340 E+ V AI+ GY HIDTA Y +E VG+ +A+ T +++FVTTK+W +K A Sbjct: 16 ELTDLVSAAIDMGYEHIDTAQFYGNEADVGKALAQH------TNKDVFVTTKVWYEKLAY 69 Query: 341 DQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSI 520 V+ +LQ S KL D IDL LIH+P P+ D + ET +Q A+Q GL + + Sbjct: 70 QDVLDSLQVSRDKLQRDTIDLALIHWP---SPN---DEVPVEETLDALQKAQQDGLIKHL 123 Query: 521 GVSNFNATQITRLVSN 568 GVSNF + R ++ Sbjct: 124 GVSNFTIDLLNRAAAH 139 >UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Lactococcus lactis|Rep: Oxidoreductase, aldo/keto reductase family - Lactococcus lactis subsp. cremoris (strain MG1363) Length = 281 Score = 87.8 bits (208), Expect = 2e-16 Identities = 59/175 (33%), Positives = 91/175 (52%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 I LNDGN IP LG + E+ AV A+ GYRHIDTA YQ+E VG+ Sbjct: 5 IVLNDGNIIPQFGLGVYQIPEGEA-----TENAVKEALRLGYRHIDTAHAYQNERSVGR- 58 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 AI + + E+++T+KLW + D A++ L+ L L IDL L+H + Sbjct: 59 ---AIHSSGIPISEIWITSKLWPSDY--DDASQAIERMLELLNLKQIDLLLLHQQVG--- 110 Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 +Y + W +++A + G +SIG+SNF+ ++ L + + I+P Q+E Sbjct: 111 -------NYRKAWIALENAVKSGKVKSIGISNFDGERLVDLFNFADIKPSALQVE 158 >UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; Sulfitobacter sp. NAS-14.1|Rep: Putative uncharacterized protein - Sulfitobacter sp. NAS-14.1 Length = 274 Score = 87.4 bits (207), Expect = 2e-16 Identities = 55/148 (37%), Positives = 75/148 (50%) Frame = +2 Query: 158 DEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHA 337 D V V A+ G+RHIDTA YQ+EEQVG+G+ A V R+E+F+TTK+ + + Sbjct: 24 DTVADMVAAALSEGFRHIDTAQAYQNEEQVGEGLRRAD----VRRDEVFLTTKILPEHFS 79 Query: 338 RDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARS 517 + A SLK+LG DY+DL L+H+P P ET + D G R Sbjct: 80 PEAFTAAADASLKRLGTDYVDLLLLHWPSKEVP--------IAETIGALNDLISAGKVRH 131 Query: 518 IGVSNFNATQITRLVSNSYIRPGXNQIE 601 GVSNF + + + NQIE Sbjct: 132 GGVSNFTMDMVDQAQAALNTPLAANQIE 159 >UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Actinobacillus succinogenes 130Z|Rep: Aldo/keto reductase precursor - Actinobacillus succinogenes 130Z Length = 315 Score = 87.0 bits (206), Expect = 3e-16 Identities = 56/175 (32%), Positives = 98/175 (56%) Frame = +2 Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256 ++LN+G +PI+ +G T ++++ ++V A++AGYR IDTA +Y++E+ VG+ Sbjct: 45 VKLNNGIEMPIIGIGVWTLTPEQTE------KSVGEALKAGYRLIDTARMYRNEQAVGR- 97 Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436 A+ + + REE+F+TTK++ + A+ E L+ L DYIDL L+H+P Sbjct: 98 ---AVRDSGIPREEIFITTKIYGSGDYAN-AEAAINERLRLLDTDYIDLLLLHYP----- 148 Query: 437 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQIE 601 D D + W+ M+ + G R+IG+SN++ R++ + I P Q E Sbjct: 149 -DQNDT----KAWKVMEQFVKAGKIRAIGLSNYHRKTFNRIMQAATITPAVVQNE 198 >UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: hypothetical protein - Ornithorhynchus anatinus Length = 419 Score = 85.8 bits (203), Expect = 7e-16 Identities = 53/140 (37%), Positives = 76/140 (54%) Frame = +2 Query: 71 PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 250 P + L +G IPI+ LGT D++ +Y E G RHIDTA Y E +G Sbjct: 13 PTVPLANGLNIPILGLGTSHVGGYSHDAV------IYALKECGIRHIDTAKRYGCELLLG 66 Query: 251 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 430 + I E+ G V REEL++TTKLW + + + ES +LG++Y+DL+LIH+P A Sbjct: 67 KAIQES---G-VKREELWITTKLWLTDYGYESAKQSCLESCNRLGVEYLDLFLIHWPDAQ 122 Query: 431 KPDDSPDNIDYLETWQGMQD 490 P S ETW+ M++ Sbjct: 123 LPGKSSREA-RAETWRAMEE 141 >UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; Oceanicola granulosus HTCC2516|Rep: 2,5-didehydrogluconate reductase - Oceanicola granulosus HTCC2516 Length = 275 Score = 85.8 bits (203), Expect = 7e-16 Identities = 59/150 (39%), Positives = 79/150 (52%) Frame = +2 Query: 104 PIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGL 283 P + G G GT D + A+ A+E GYRH+DTA Y E +VG+ I A GL Sbjct: 9 PEIMPGLGFGTYGRQGE-DGI-SAILCALETGYRHLDTAQDYDTEAEVGEAIRRA---GL 63 Query: 284 VTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDY 463 RE LFVTTK+ +VP++ SL+ +GLD DL LIH+P P+ DY Sbjct: 64 -PREALFVTTKVRPANFGPGDLVPSVARSLETMGLDRADLVLIHWP---APNGERPLSDY 119 Query: 464 LETWQGMQDARQLGLARSIGVSNFNATQIT 553 + + +AR GL R +GVSNF +T Sbjct: 120 IPQ---LAEARAQGLTRHVGVSNFPVALLT 146 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 617,181,928 Number of Sequences: 1657284 Number of extensions: 12255494 Number of successful extensions: 38549 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 36461 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 37770 length of database: 575,637,011 effective HSP length: 97 effective length of database: 414,880,463 effective search space used: 43147568152 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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