Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= epV31104
(606 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 155 1e-37
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 155 1e-37
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 155 1e-37
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 155 1e-37
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 155 1e-37
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 155 1e-37
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 155 1e-37
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 155 1e-37
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 155 1e-37
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 155 1e-37
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 155 1e-37
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 155 1e-37
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 154 2e-37
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 154 2e-37
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 154 2e-37
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 154 2e-37
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 154 2e-37
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 154 2e-37
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 154 2e-37
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 154 2e-37
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 154 2e-37
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 154 2e-37
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 151 1e-36
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 151 1e-36
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 151 2e-36
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 151 2e-36
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 151 2e-36
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 151 2e-36
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 151 2e-36
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 151 2e-36
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 150 3e-36
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 150 3e-36
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 150 3e-36
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 150 3e-36
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 150 3e-36
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 150 3e-36
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 150 3e-36
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 150 4e-36
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 149 6e-36
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 149 6e-36
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 148 2e-35
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 145 1e-34
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 145 1e-34
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 145 1e-34
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 145 1e-34
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 145 1e-34
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 145 1e-34
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 145 1e-34
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 145 1e-34
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 140 3e-33
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 140 3e-33
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 136 7e-32
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 136 7e-32
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 136 7e-32
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 136 7e-32
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 134 2e-31
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 133 4e-31
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 132 7e-31
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 132 7e-31
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 132 7e-31
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 132 7e-31
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 132 7e-31
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 132 7e-31
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 132 7e-31
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 132 7e-31
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 132 7e-31
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 132 7e-31
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 132 7e-31
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 132 7e-31
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 127 3e-29
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 122 1e-27
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 122 1e-27
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 122 1e-27
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 122 1e-27
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 122 1e-27
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 119 7e-27
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 117 3e-26
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 110 6e-26
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 115 1e-25
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 115 1e-25
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 115 1e-25
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 115 1e-25
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 115 1e-25
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 109 1e-23
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 97 4e-20
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 97 4e-20
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 97 4e-20
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 97 4e-20
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 97 4e-20
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 97 4e-20
Y16675-1|CAA76347.1| 330|Homo sapiens aflatoxin B1-aldehyde red... 44 3e-04
BT007347-1|AAP36011.1| 330|Homo sapiens aldo-keto reductase fam... 44 3e-04
BC013996-1|AAH13996.1| 330|Homo sapiens AKR7A2 protein protein. 44 3e-04
BC012171-1|AAH12171.1| 330|Homo sapiens AKR7A2 protein protein. 44 3e-04
BC011586-1|AAH11586.1| 330|Homo sapiens AKR7A2 protein protein. 44 3e-04
BC010852-1|AAH10852.1| 330|Homo sapiens AKR7A2 protein protein. 44 3e-04
BC007352-1|AAH07352.2| 358|Homo sapiens AKR7A2 protein protein. 44 3e-04
BC004111-1|AAH04111.3| 330|Homo sapiens AKR7A2 protein protein. 44 3e-04
AL035413-8|CAB72321.1| 330|Homo sapiens aldo-keto reductase fam... 44 3e-04
AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde redu... 44 3e-04
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 44 6e-04
AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto red... 41 0.003
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 40 0.007
AF040639-1|AAD02195.1| 331|Homo sapiens aflatoxin B1-aldehyde r... 40 0.007
BC042420-1|AAH42420.2| 331|Homo sapiens aldo-keto reductase fam... 38 0.021
BC031562-1|AAH31562.1| 331|Homo sapiens aldo-keto reductase fam... 38 0.021
AJ271799-1|CAC81076.1| 331|Homo sapiens aflatoxin B1 aldehyde r... 38 0.021
BC025709-1|AAH25709.1| 331|Homo sapiens aldo-keto reductase fam... 38 0.036
AL035413-11|CAI22232.1| 331|Homo sapiens aldo-keto reductase fa... 38 0.036
L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine sy... 35 0.26
CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein. 35 0.26
BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine liga... 35 0.26
AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine liga... 35 0.26
AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine lig... 35 0.26
AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine liga... 35 0.26
AJ278012-1|CAC79668.1| 259|Homo sapiens aflatoxin B1 aldehyde r... 32 1.4
BC117495-1|AAI17496.1| 905|Homo sapiens stonin 2 protein. 30 7.3
BC117493-1|AAI17494.1| 905|Homo sapiens stonin 2 protein. 30 7.3
BC069587-1|AAH69587.1| 904|Homo sapiens STON2 protein protein. 30 7.3
BC069502-1|AAH69502.1| 905|Homo sapiens stonin 2 protein. 30 7.3
BC069389-1|AAH69389.1| 905|Homo sapiens stonin 2 protein. 30 7.3
BC069359-1|AAH69359.1| 905|Homo sapiens stonin 2 protein. 30 7.3
AF449430-1|AAL47008.1| 905|Homo sapiens endocytosis protein HST... 30 7.3
AF380833-1|AAK76362.1| 886|Homo sapiens endocytosis protein HST... 30 7.3
AF255309-1|AAK57558.1| 702|Homo sapiens stonin 2 protein. 30 7.3
AB208948-1|BAD92185.1| 932|Homo sapiens Stonin 2 variant protein. 30 7.3
M80469-1|AAA36307.1| 28|Homo sapiens MHC class I HLA-J antigen... 29 9.6
M80468-1|AAA36306.1| 28|Homo sapiens MHC class I HLA-J antigen... 29 9.6
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 155 bits (376), Expect = 1e-37
Identities = 81/189 (42%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT A + +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 434 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 155 bits (376), Expect = 1e-37
Identities = 81/189 (42%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT A + +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 434 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 580
P + D +D TW+ M+ + GLA+SIGVSNFN + +++ ++
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLK 183
Query: 581 --PGXNQIE 601
P NQ+E
Sbjct: 184 YEPVCNQVE 192
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 155 bits (376), Expect = 1e-37
Identities = 82/189 (43%), Positives = 115/189 (60%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT A + +AV AIEAGY HID+A VY +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGYHHIDSAHVYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLIHFPVSVK 123
Query: 434 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 580
P + D +D TW+ M+ + GLA+SIGVSNFN + +++ ++
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLK 183
Query: 581 --PGXNQIE 601
P NQ+E
Sbjct: 184 YEPVCNQVE 192
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 155 bits (376), Expect = 1e-37
Identities = 81/189 (42%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT A + +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 434 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 155 bits (376), Expect = 1e-37
Identities = 81/189 (42%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT A + +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 434 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 155 bits (376), Expect = 1e-37
Identities = 81/189 (42%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT A + +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 434 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 155 bits (376), Expect = 1e-37
Identities = 81/189 (42%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT A + +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 434 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 155 bits (376), Expect = 1e-37
Identities = 81/189 (42%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT A + +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 434 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 155 bits (376), Expect = 1e-37
Identities = 81/189 (42%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT A + +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 20 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGL 76
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 77 AIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 136
Query: 434 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 137 PGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLK 196
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 197 YKPVCNQVE 205
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 155 bits (376), Expect = 1e-37
Identities = 81/189 (42%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT A + +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 434 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 155 bits (376), Expect = 1e-37
Identities = 81/189 (42%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT A + +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 434 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 155 bits (376), Expect = 1e-37
Identities = 81/189 (42%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT A + +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 434 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 154 bits (374), Expect = 2e-37
Identities = 80/189 (42%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT A + +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 434 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 154 bits (374), Expect = 2e-37
Identities = 80/189 (42%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT A + +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 434 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 154 bits (374), Expect = 2e-37
Identities = 80/189 (42%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT A + +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 434 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 154 bits (374), Expect = 2e-37
Identities = 80/189 (42%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT A + +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 434 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 154 bits (374), Expect = 2e-37
Identities = 80/189 (42%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT A + +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 434 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 154 bits (374), Expect = 2e-37
Identities = 80/189 (42%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT A + +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 434 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 154 bits (374), Expect = 2e-37
Identities = 80/189 (42%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT A + +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 434 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 154 bits (374), Expect = 2e-37
Identities = 80/189 (42%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT A + +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 434 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 154 bits (374), Expect = 2e-37
Identities = 80/189 (42%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT A + +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 434 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 154 bits (374), Expect = 2e-37
Identities = 80/189 (42%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT A + +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 434 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 151 bits (367), Expect = 1e-36
Identities = 81/189 (42%), Positives = 117/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT A + +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
+ IA+G V RE++F T+KLW + H + V PAL+ SLKK LDY+DLYLIH P++ K
Sbjct: 64 AVRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHSPMSLK 123
Query: 434 PDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 151 bits (367), Expect = 1e-36
Identities = 82/189 (43%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT EV + AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGTYAPPEVPRSKALEVSKL---AIEAGFRHIDSAHLYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK 123
Query: 434 PDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 151 bits (366), Expect = 2e-36
Identities = 81/188 (43%), Positives = 115/188 (61%), Gaps = 13/188 (6%)
Frame = +2
Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
++LNDG+ +P++ GT + EV + AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
I IA+G V RE++F T+KLW V PAL+ SLKKL LDY+DLYL+HFP+A KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 124
Query: 437 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 577
++P D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GETPLPKDENGKVIFDTVDLCATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKY 184
Query: 578 RPGXNQIE 601
+P NQ+E
Sbjct: 185 KPVCNQVE 192
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 151 bits (365), Expect = 2e-36
Identities = 81/188 (43%), Positives = 115/188 (61%), Gaps = 13/188 (6%)
Frame = +2
Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
++LNDG+ +P++ GT + EV + AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
I IA+G V RE++F T+KLW V PAL+ SLKKL LDY+DLYL+HFP+A KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 124
Query: 437 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 577
++P D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKY 184
Query: 578 RPGXNQIE 601
+P NQ+E
Sbjct: 185 KPVCNQVE 192
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 151 bits (365), Expect = 2e-36
Identities = 81/188 (43%), Positives = 115/188 (61%), Gaps = 13/188 (6%)
Frame = +2
Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
++LNDG+ +P++ GT + EV + AIEAG+RHID+A +Y +EEQVG
Sbjct: 6 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 62
Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
I IA+G V RE++F T+KLW V PAL+ SLKKL LDY+DLYL+HFP+A KP
Sbjct: 63 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 122
Query: 437 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 577
++P D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 123 GETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKY 182
Query: 578 RPGXNQIE 601
+P NQ+E
Sbjct: 183 KPVCNQVE 190
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 151 bits (365), Expect = 2e-36
Identities = 81/188 (43%), Positives = 115/188 (61%), Gaps = 13/188 (6%)
Frame = +2
Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
++LNDG+ +P++ GT + EV + AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
I IA+G V RE++F T+KLW V PAL+ SLKKL LDY+DLYL+HFP+A KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 124
Query: 437 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 577
++P D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKY 184
Query: 578 RPGXNQIE 601
+P NQ+E
Sbjct: 185 KPVCNQVE 192
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 151 bits (365), Expect = 2e-36
Identities = 81/188 (43%), Positives = 115/188 (61%), Gaps = 13/188 (6%)
Frame = +2
Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
++LNDG+ +P++ GT + EV + AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
I IA+G V RE++F T+KLW V PAL+ SLKKL LDY+DLYL+HFP+A KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 124
Query: 437 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 577
++P D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKY 184
Query: 578 RPGXNQIE 601
+P NQ+E
Sbjct: 185 KPVCNQVE 192
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 151 bits (365), Expect = 2e-36
Identities = 81/188 (43%), Positives = 115/188 (61%), Gaps = 13/188 (6%)
Frame = +2
Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
++LNDG+ +P++ GT + EV + AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
I IA+G V RE++F T+KLW V PAL+ SLKKL LDY+DLYL+HFP+A KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 124
Query: 437 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 577
++P D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKY 184
Query: 578 RPGXNQIE 601
+P NQ+E
Sbjct: 185 KPVCNQVE 192
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 150 bits (364), Expect = 3e-36
Identities = 82/189 (43%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT EV + AIEAG+RHID+A +Y +EEQVG
Sbjct: 9 CVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGL 65
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P++ K
Sbjct: 66 AIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK 125
Query: 434 PDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 126 PGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 185
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 186 YKPVCNQVE 194
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 150 bits (364), Expect = 3e-36
Identities = 82/189 (43%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT EV + AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK 123
Query: 434 PDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 150 bits (364), Expect = 3e-36
Identities = 82/189 (43%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT EV + AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK 123
Query: 434 PDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 150 bits (364), Expect = 3e-36
Identities = 82/189 (43%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT EV + AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK 123
Query: 434 PDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 150 bits (364), Expect = 3e-36
Identities = 82/189 (43%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT EV + AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK 123
Query: 434 PDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 150 bits (364), Expect = 3e-36
Identities = 82/189 (43%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT EV + AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK 123
Query: 434 PDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 150 bits (364), Expect = 3e-36
Identities = 82/189 (43%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT EV + AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK 123
Query: 434 PDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 150 bits (363), Expect = 4e-36
Identities = 81/188 (43%), Positives = 115/188 (61%), Gaps = 13/188 (6%)
Frame = +2
Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
++LNDG+ +P++ GT + EV + AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
I IA+G V RE++F T+KLW V PAL+ SLKKL LDY+DLYL+HFP+A KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 124
Query: 437 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 577
++P D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKPGLKY 184
Query: 578 RPGXNQIE 601
+P NQ+E
Sbjct: 185 KPVCNQVE 192
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 149 bits (362), Expect = 6e-36
Identities = 82/189 (43%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT EV + AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P++ K
Sbjct: 64 AIRSKIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK 123
Query: 434 PDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 149 bits (362), Expect = 6e-36
Identities = 82/189 (43%), Positives = 116/189 (61%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT EV + AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGL 63
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P++ K
Sbjct: 64 AIRSKIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK 123
Query: 434 PDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 577
P + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLK 183
Query: 578 -RPGXNQIE 601
+P NQ+E
Sbjct: 184 YKPVCNQVE 192
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 148 bits (358), Expect = 2e-35
Identities = 77/189 (40%), Positives = 114/189 (60%), Gaps = 13/189 (6%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 253
C++LNDG+ +P++ GT A + +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 4 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGL 60
Query: 254 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 433
I IA+G V RE++F T+KLW + H + PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 61 AIRSKIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHFPVSVK 120
Query: 434 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS--Y 574
P + D +D TW+ ++ + LA+SIGVSNFN + + +++
Sbjct: 121 PGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAELAKSIGVSNFNRSTLEMILNKPGLQ 180
Query: 575 IRPGXNQIE 601
++P NQ+E
Sbjct: 181 VKPVCNQVE 189
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 145 bits (351), Expect = 1e-34
Identities = 75/190 (39%), Positives = 117/190 (61%), Gaps = 12/190 (6%)
Frame = +2
Query: 68 APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247
A C+ L+ G +P++ LGT + +V+ AV +A+ GYRHID AA+Y +E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 248 GQGIAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424
G+ + E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 425 ATKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 571
A + D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI ++S +
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176
Query: 572 YIRPGXNQIE 601
+RP Q+E
Sbjct: 177 SVRPAVLQVE 186
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 145 bits (351), Expect = 1e-34
Identities = 75/190 (39%), Positives = 117/190 (61%), Gaps = 12/190 (6%)
Frame = +2
Query: 68 APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247
A C+ L+ G +P++ LGT + +V+ AV +A+ GYRHID AA+Y +E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 248 GQGIAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424
G+ + E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 425 ATKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 571
A + D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI ++S +
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176
Query: 572 YIRPGXNQIE 601
+RP Q+E
Sbjct: 177 SVRPAVLQVE 186
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 145 bits (351), Expect = 1e-34
Identities = 75/190 (39%), Positives = 117/190 (61%), Gaps = 12/190 (6%)
Frame = +2
Query: 68 APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247
A C+ L+ G +P++ LGT + +V+ AV +A+ GYRHID AA+Y +E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 248 GQGIAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424
G+ + E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 425 ATKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 571
A + D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI ++S +
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176
Query: 572 YIRPGXNQIE 601
+RP Q+E
Sbjct: 177 SVRPAVLQVE 186
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 145 bits (351), Expect = 1e-34
Identities = 75/190 (39%), Positives = 117/190 (61%), Gaps = 12/190 (6%)
Frame = +2
Query: 68 APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247
A C+ L+ G +P++ LGT + +V+ AV +A+ GYRHID AA+Y +E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 248 GQGIAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424
G+ + E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 425 ATKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 571
A + D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI ++S +
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176
Query: 572 YIRPGXNQIE 601
+RP Q+E
Sbjct: 177 SVRPAVLQVE 186
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 145 bits (351), Expect = 1e-34
Identities = 75/190 (39%), Positives = 117/190 (61%), Gaps = 12/190 (6%)
Frame = +2
Query: 68 APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247
A C+ L+ G +P++ LGT + +V+ AV +A+ GYRHID AA+Y +E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 248 GQGIAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424
G+ + E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 425 ATKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 571
A + D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI ++S +
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176
Query: 572 YIRPGXNQIE 601
+RP Q+E
Sbjct: 177 SVRPAVLQVE 186
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 145 bits (351), Expect = 1e-34
Identities = 75/190 (39%), Positives = 117/190 (61%), Gaps = 12/190 (6%)
Frame = +2
Query: 68 APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247
A C+ L+ G +P++ LGT + +V+ AV +A+ GYRHID AA+Y +E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 248 GQGIAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424
G+ + E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 425 ATKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 571
A + D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI ++S +
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176
Query: 572 YIRPGXNQIE 601
+RP Q+E
Sbjct: 177 SVRPAVLQVE 186
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 145 bits (351), Expect = 1e-34
Identities = 75/190 (39%), Positives = 117/190 (61%), Gaps = 12/190 (6%)
Frame = +2
Query: 68 APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247
A C+ L+ G +P++ LGT + +V+ AV +A+ GYRHID AA+Y +E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 248 GQGIAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424
G+ + E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 425 ATKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 571
A + D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI ++S +
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176
Query: 572 YIRPGXNQIE 601
+RP Q+E
Sbjct: 177 SVRPAVLQVE 186
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 145 bits (351), Expect = 1e-34
Identities = 75/190 (39%), Positives = 117/190 (61%), Gaps = 12/190 (6%)
Frame = +2
Query: 68 APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247
A C+ L+ G +P++ LGT + +V+ AV +A+ GYRHID AA+Y +E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 248 GQGIAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424
G+ + E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 425 ATKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 571
A + D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI ++S +
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176
Query: 572 YIRPGXNQIE 601
+RP Q+E
Sbjct: 177 SVRPAVLQVE 186
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 140 bits (340), Expect = 3e-33
Identities = 71/157 (45%), Positives = 100/157 (63%), Gaps = 13/157 (8%)
Frame = +2
Query: 170 QAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQV 349
+A AIEAG+RHID+A +Y +EEQVG I IA+G V RE++F T+KLW + H + V
Sbjct: 19 EATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELV 78
Query: 350 VPALQESLKKLGLDYIDLYLIHFPIATKPDDSP-----------DNIDYLETWQGMQDAR 496
PAL+ SLK L LDY+DLYLIHFP++ KP + D +D TW+ ++ +
Sbjct: 79 RPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCK 138
Query: 497 QLGLARSIGVSNFNATQITRLVSNSYI--RPGXNQIE 601
GLA+SIGVSNFN Q+ +++ + +P NQ+E
Sbjct: 139 DAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 175
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 140 bits (339), Expect = 3e-33
Identities = 72/152 (47%), Positives = 98/152 (64%), Gaps = 13/152 (8%)
Frame = +2
Query: 185 AIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQ 364
AIEAG+RHID+A +Y +EEQVG I IA+G V RE++F T+KLW V PAL+
Sbjct: 26 AIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALE 85
Query: 365 ESLKKLGLDYIDLYLIHFPIATKPDDSP-----------DNIDYLETWQGMQDARQLGLA 511
SLKKL LDY+DLYL+HFP+A KP ++P D +D TW+ M+ + GLA
Sbjct: 86 SSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLA 145
Query: 512 RSIGVSNFNATQITRLVSNSYI--RPGXNQIE 601
+SIGVSNFN Q+ +++ + +P NQ+E
Sbjct: 146 KSIGVSNFNCRQLEMILNKPGLKYKPVCNQVE 177
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 136 bits (328), Expect = 7e-32
Identities = 76/188 (40%), Positives = 110/188 (58%), Gaps = 13/188 (6%)
Frame = +2
Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
I L+DGN+IPI+ LGT + +S +V AI+ GYRHID A +YQ+E +VG+
Sbjct: 10 IPLSDGNSIPIIGLGTY--SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEA 67
Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
I E IA G V RE++F KLW H + V P L+ +L+ L LDY+DLY+I P+A KP
Sbjct: 68 IREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKP 127
Query: 437 DDS----PDNIDYL-------ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 577
D +N +L TW+ M+ + GL +S+GVSNFN Q+ +++ +
Sbjct: 128 GDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKH 187
Query: 578 RPGXNQIE 601
+P NQ+E
Sbjct: 188 KPVSNQVE 195
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 136 bits (328), Expect = 7e-32
Identities = 76/188 (40%), Positives = 110/188 (58%), Gaps = 13/188 (6%)
Frame = +2
Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
I L+DGN+IPI+ LGT + +S +V AI+ GYRHID A +YQ+E +VG+
Sbjct: 10 IPLSDGNSIPIIGLGTY--SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEA 67
Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
I E IA G V RE++F KLW H + V P L+ +L+ L LDY+DLY+I P+A KP
Sbjct: 68 IREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKP 127
Query: 437 DDS----PDNIDYL-------ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 577
D +N +L TW+ M+ + GL +S+GVSNFN Q+ +++ +
Sbjct: 128 GDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKH 187
Query: 578 RPGXNQIE 601
+P NQ+E
Sbjct: 188 KPVSNQVE 195
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 136 bits (328), Expect = 7e-32
Identities = 76/188 (40%), Positives = 110/188 (58%), Gaps = 13/188 (6%)
Frame = +2
Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
I L+DGN+IPI+ LGT + +S +V AI+ GYRHID A +YQ+E +VG+
Sbjct: 10 IPLSDGNSIPIIGLGTY--SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEA 67
Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
I E IA G V RE++F KLW H + V P L+ +L+ L LDY+DLY+I P+A KP
Sbjct: 68 IREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKP 127
Query: 437 DDS----PDNIDYL-------ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 577
D +N +L TW+ M+ + GL +S+GVSNFN Q+ +++ +
Sbjct: 128 GDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKH 187
Query: 578 RPGXNQIE 601
+P NQ+E
Sbjct: 188 KPVSNQVE 195
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 136 bits (328), Expect = 7e-32
Identities = 76/188 (40%), Positives = 110/188 (58%), Gaps = 13/188 (6%)
Frame = +2
Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
I L+DGN+IPI+ LGT + +S +V AI+ GYRHID A +YQ+E +VG+
Sbjct: 10 IPLSDGNSIPIIGLGTY--SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEA 67
Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
I E IA G V RE++F KLW H + V P L+ +L+ L LDY+DLY+I P+A KP
Sbjct: 68 IREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKP 127
Query: 437 DDS----PDNIDYL-------ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 577
D +N +L TW+ M+ + GL +S+GVSNFN Q+ +++ +
Sbjct: 128 GDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKH 187
Query: 578 RPGXNQIE 601
+P NQ+E
Sbjct: 188 KPVSNQVE 195
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 134 bits (325), Expect = 2e-31
Identities = 77/186 (41%), Positives = 110/186 (59%), Gaps = 13/186 (6%)
Frame = +2
Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 436
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+PI KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPIGFKPGK 120
Query: 437 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 583
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 584 GXNQIE 601
NQIE
Sbjct: 181 AVNQIE 186
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 133 bits (322), Expect = 4e-31
Identities = 77/188 (40%), Positives = 110/188 (58%), Gaps = 13/188 (6%)
Frame = +2
Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
I LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG
Sbjct: 5 ILLNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVA 58
Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
I E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 59 IQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP 118
Query: 437 -------DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 577
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ +
Sbjct: 119 GKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKY 178
Query: 578 RPGXNQIE 601
+P NQIE
Sbjct: 179 KPAVNQIE 186
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 132 bits (320), Expect = 7e-31
Identities = 76/186 (40%), Positives = 109/186 (58%), Gaps = 13/186 (6%)
Frame = +2
Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 436
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 437 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 583
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 584 GXNQIE 601
NQIE
Sbjct: 181 AVNQIE 186
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 132 bits (320), Expect = 7e-31
Identities = 76/186 (40%), Positives = 109/186 (58%), Gaps = 13/186 (6%)
Frame = +2
Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 436
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 437 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 583
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 584 GXNQIE 601
NQIE
Sbjct: 181 AVNQIE 186
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 132 bits (320), Expect = 7e-31
Identities = 76/186 (40%), Positives = 109/186 (58%), Gaps = 13/186 (6%)
Frame = +2
Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 436
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 437 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 583
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 584 GXNQIE 601
NQIE
Sbjct: 181 AVNQIE 186
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 132 bits (320), Expect = 7e-31
Identities = 76/186 (40%), Positives = 109/186 (58%), Gaps = 13/186 (6%)
Frame = +2
Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 436
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 437 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 583
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 584 GXNQIE 601
NQIE
Sbjct: 181 AVNQIE 186
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 132 bits (320), Expect = 7e-31
Identities = 76/186 (40%), Positives = 109/186 (58%), Gaps = 13/186 (6%)
Frame = +2
Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 436
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 437 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 583
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 584 GXNQIE 601
NQIE
Sbjct: 181 AVNQIE 186
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 132 bits (320), Expect = 7e-31
Identities = 76/186 (40%), Positives = 109/186 (58%), Gaps = 13/186 (6%)
Frame = +2
Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 436
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P +P
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFRPGK 120
Query: 437 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 583
D+S P + + L+TW M++ GL ++IG+SNFN Q+ ++S + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILSKPGLKYKP 180
Query: 584 GXNQIE 601
NQIE
Sbjct: 181 AVNQIE 186
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 132 bits (320), Expect = 7e-31
Identities = 76/186 (40%), Positives = 109/186 (58%), Gaps = 13/186 (6%)
Frame = +2
Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 436
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 437 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 583
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 584 GXNQIE 601
NQIE
Sbjct: 181 AVNQIE 186
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 132 bits (320), Expect = 7e-31
Identities = 76/186 (40%), Positives = 109/186 (58%), Gaps = 13/186 (6%)
Frame = +2
Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 436
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 437 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 583
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 584 GXNQIE 601
NQIE
Sbjct: 181 AVNQIE 186
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 132 bits (320), Expect = 7e-31
Identities = 76/186 (40%), Positives = 109/186 (58%), Gaps = 13/186 (6%)
Frame = +2
Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 436
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 437 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 583
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 584 GXNQIE 601
NQIE
Sbjct: 181 AVNQIE 186
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 132 bits (320), Expect = 7e-31
Identities = 76/186 (40%), Positives = 109/186 (58%), Gaps = 13/186 (6%)
Frame = +2
Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 436
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 437 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 583
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 584 GXNQIE 601
NQIE
Sbjct: 181 AVNQIE 186
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 132 bits (320), Expect = 7e-31
Identities = 76/186 (40%), Positives = 109/186 (58%), Gaps = 13/186 (6%)
Frame = +2
Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 436
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 437 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 583
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 584 GXNQIE 601
NQIE
Sbjct: 181 AVNQIE 186
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 132 bits (320), Expect = 7e-31
Identities = 76/186 (40%), Positives = 109/186 (58%), Gaps = 13/186 (6%)
Frame = +2
Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 4 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 57
Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 436
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 58 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 117
Query: 437 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 583
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 118 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 177
Query: 584 GXNQIE 601
NQIE
Sbjct: 178 AVNQIE 183
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 127 bits (306), Expect = 3e-29
Identities = 75/186 (40%), Positives = 108/186 (58%), Gaps = 13/186 (6%)
Frame = +2
Query: 83 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 262
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 263 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 436
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 437 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 583
D+S P + + L+T M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTRAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 584 GXNQIE 601
NQIE
Sbjct: 181 AVNQIE 186
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 122 bits (294), Expect = 1e-27
Identities = 73/191 (38%), Positives = 110/191 (57%), Gaps = 13/191 (6%)
Frame = +2
Query: 68 APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247
A ++L+ +PIV LGT + + +V++AV AI+AGYRHID A VYQ+E +V
Sbjct: 2 ATFVELSTKAKMPIVGLGTWKSP------LGKVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 248 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427
G+ I E I V RE+LF+ +KLW R V A +++LK L L Y+D+YLIH+P
Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115
Query: 428 TK------PDDSPDN-----IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 574
K P D N +L+ W+ M++ GL +++GVSNF+ QI +L++
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175
Query: 575 I--RPGXNQIE 601
+ +P NQ+E
Sbjct: 176 LKYKPVTNQVE 186
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 122 bits (294), Expect = 1e-27
Identities = 73/191 (38%), Positives = 110/191 (57%), Gaps = 13/191 (6%)
Frame = +2
Query: 68 APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247
A ++L+ +PIV LGT + + +V++AV AI+AGYRHID A VYQ+E +V
Sbjct: 2 ATFVELSTKAKMPIVGLGTWKSP------LGKVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 248 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427
G+ I E I V RE+LF+ +KLW R V A +++LK L L Y+D+YLIH+P
Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115
Query: 428 TK------PDDSPDN-----IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 574
K P D N +L+ W+ M++ GL +++GVSNF+ QI +L++
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175
Query: 575 I--RPGXNQIE 601
+ +P NQ+E
Sbjct: 176 LKYKPVTNQVE 186
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 122 bits (294), Expect = 1e-27
Identities = 73/191 (38%), Positives = 110/191 (57%), Gaps = 13/191 (6%)
Frame = +2
Query: 68 APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247
A ++L+ +PIV LGT + + +V++AV AI+AGYRHID A VYQ+E +V
Sbjct: 2 ATFVELSTKAKMPIVGLGTWKSP------LGKVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 248 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427
G+ I E I V RE+LF+ +KLW R V A +++LK L L Y+D+YLIH+P
Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115
Query: 428 TK------PDDSPDN-----IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 574
K P D N +L+ W+ M++ GL +++GVSNF+ QI +L++
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175
Query: 575 I--RPGXNQIE 601
+ +P NQ+E
Sbjct: 176 LKYKPVTNQVE 186
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 122 bits (294), Expect = 1e-27
Identities = 73/191 (38%), Positives = 110/191 (57%), Gaps = 13/191 (6%)
Frame = +2
Query: 68 APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247
A ++L+ +PIV LGT + + +V++AV AI+AGYRHID A VYQ+E +V
Sbjct: 2 ATFVELSTKAKMPIVGLGTWKSP------LGKVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 248 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427
G+ I E I V RE+LF+ +KLW R V A +++LK L L Y+D+YLIH+P
Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115
Query: 428 TK------PDDSPDN-----IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 574
K P D N +L+ W+ M++ GL +++GVSNF+ QI +L++
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175
Query: 575 I--RPGXNQIE 601
+ +P NQ+E
Sbjct: 176 LKYKPVTNQVE 186
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 122 bits (294), Expect = 1e-27
Identities = 73/191 (38%), Positives = 110/191 (57%), Gaps = 13/191 (6%)
Frame = +2
Query: 68 APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247
A ++L+ +PIV LGT + + +V++AV AI+AGYRHID A VYQ+E +V
Sbjct: 2 ATFVELSTKAKMPIVGLGTWKSP------LGKVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 248 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427
G+ I E I V RE+LF+ +KLW R V A +++LK L L Y+D+YLIH+P
Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115
Query: 428 TK------PDDSPDN-----IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 574
K P D N +L+ W+ M++ GL +++GVSNF+ QI +L++
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175
Query: 575 I--RPGXNQIE 601
+ +P NQ+E
Sbjct: 176 LKYKPVTNQVE 186
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 119 bits (287), Expect = 7e-27
Identities = 72/191 (37%), Positives = 109/191 (57%), Gaps = 13/191 (6%)
Frame = +2
Query: 68 APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247
A ++L+ +PIV LGT + + +V++AV AI+AGYRHID A VYQ+E +V
Sbjct: 2 ATFVELSTKAKMPIVGLGTWKSP------LGKVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 248 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 427
G+ I E I V RE+LF+ +KLW R V A +++LK L Y+D+YLIH+P
Sbjct: 56 GEAIQEKIQEKAVKREDLFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQG 115
Query: 428 TK------PDDSPDN-----IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 574
K P D N +L+ W+ M++ GL +++GVSNF+ QI +L++
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175
Query: 575 I--RPGXNQIE 601
+ +P NQ+E
Sbjct: 176 LKYKPVTNQVE 186
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 117 bits (282), Expect = 3e-26
Identities = 61/151 (40%), Positives = 92/151 (60%), Gaps = 12/151 (7%)
Frame = +2
Query: 68 APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 247
A C+ L+ G +P++ LGT + +V+ AV +A+ GYRHID AA+Y +E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 248 GQGIAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424
G+ + E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 425 ATKPDDSP-----------DNIDYLETWQGM 484
A + D+P D+ Y ETW+ +
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKAL 147
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 110 bits (264), Expect(2) = 6e-26
Identities = 56/133 (42%), Positives = 81/133 (60%), Gaps = 13/133 (9%)
Frame = +2
Query: 242 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 421
+VG I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP
Sbjct: 26 EVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 85
Query: 422 IATKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSN 568
++ KP + D +D TW+ ++ + GLA+SIGVSNFN Q+ +++
Sbjct: 86 VSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 145
Query: 569 SYI--RPGXNQIE 601
+ +P NQ+E
Sbjct: 146 PGLKYKPVCNQVE 158
Score = 27.1 bits (57), Expect(2) = 6e-26
Identities = 8/17 (47%), Positives = 14/17 (82%)
Frame = +2
Query: 74 CIQLNDGNTIPIVALGT 124
C++LNDG+ +P++ GT
Sbjct: 5 CVKLNDGHFMPVLGFGT 21
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 115 bits (277), Expect = 1e-25
Identities = 58/123 (47%), Positives = 80/123 (65%)
Frame = +2
Query: 65 QAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 244
Q+ ++LNDG +P++ GT A + + +A AI+ G+RHID+A +YQ+EE+
Sbjct: 7 QSHSVRLNDGPFMPVLGFGT---YAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEE 63
Query: 245 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424
VGQ I E IA+G V REE+F T KLW + V PAL+ SLKKLG DY+DL++IH P
Sbjct: 64 VGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPF 123
Query: 425 ATK 433
A K
Sbjct: 124 AMK 126
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 115 bits (277), Expect = 1e-25
Identities = 58/123 (47%), Positives = 80/123 (65%)
Frame = +2
Query: 65 QAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 244
Q+ ++LNDG +P++ GT A + + +A AI+ G+RHID+A +YQ+EE+
Sbjct: 7 QSHSVRLNDGPFMPVLGFGT---YAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEE 63
Query: 245 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424
VGQ I E IA+G V REE+F T KLW + V PAL+ SLKKLG DY+DL++IH P
Sbjct: 64 VGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPF 123
Query: 425 ATK 433
A K
Sbjct: 124 AMK 126
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 115 bits (277), Expect = 1e-25
Identities = 58/123 (47%), Positives = 80/123 (65%)
Frame = +2
Query: 65 QAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 244
Q+ ++LNDG +P++ GT A + + +A AI+ G+RHID+A +YQ+EE+
Sbjct: 7 QSHSVRLNDGPFMPVLGFGT---YAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEE 63
Query: 245 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424
VGQ I E IA+G V REE+F T KLW + V PAL+ SLKKLG DY+DL++IH P
Sbjct: 64 VGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPF 123
Query: 425 ATK 433
A K
Sbjct: 124 AMK 126
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 115 bits (277), Expect = 1e-25
Identities = 58/123 (47%), Positives = 80/123 (65%)
Frame = +2
Query: 65 QAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 244
Q+ ++LNDG +P++ GT A + + +A AI+ G+RHID+A +YQ+EE+
Sbjct: 7 QSHSVRLNDGPFMPVLGFGT---YAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEE 63
Query: 245 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424
VGQ I E IA+G V REE+F T KLW + V PAL+ SLKKLG DY+DL++IH P
Sbjct: 64 VGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPF 123
Query: 425 ATK 433
A K
Sbjct: 124 AMK 126
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 115 bits (277), Expect = 1e-25
Identities = 58/123 (47%), Positives = 80/123 (65%)
Frame = +2
Query: 65 QAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 244
Q+ ++LNDG +P++ GT A + + +A AI+ G+RHID+A +YQ+EE+
Sbjct: 7 QSHSVRLNDGPFMPVLGFGT---YAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEE 63
Query: 245 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 424
VGQ I E IA+G V REE+F T KLW + V PAL+ SLKKLG DY+DL++IH P
Sbjct: 64 VGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPF 123
Query: 425 ATK 433
A K
Sbjct: 124 AMK 126
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 109 bits (261), Expect = 1e-23
Identities = 54/123 (43%), Positives = 77/123 (62%)
Frame = +2
Query: 77 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 256
++LNDG +PI+ GT + ++ V +AV AI+ GYRHID+A + +EE +GQ
Sbjct: 9 VKLNDGKFMPILGFGT---SVARKVAMSNVEEAVQVAIDVGYRHIDSAYTHLNEEGIGQA 65
Query: 257 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
I + IANG V R+++F TTK+W + V L+ SLKKL L Y+DLYL HFP+ +P
Sbjct: 66 IRKKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPLQP 125
Query: 437 DDS 445
S
Sbjct: 126 GRS 128
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 97.1 bits (231), Expect = 4e-20
Identities = 49/102 (48%), Positives = 64/102 (62%)
Frame = +2
Query: 131 GTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 310
G + S +V +AV AI+AGYRH D A Y +E +VG GI I G V RE+LF+
Sbjct: 8 GLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIA 67
Query: 311 TKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
TKLW H + V A ++SLK L L+Y+DLYLIH+P+ KP
Sbjct: 68 TKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 97.1 bits (231), Expect = 4e-20
Identities = 49/102 (48%), Positives = 64/102 (62%)
Frame = +2
Query: 131 GTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 310
G + S +V +AV AI+AGYRH D A Y +E +VG GI I G V RE+LF+
Sbjct: 8 GLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIA 67
Query: 311 TKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
TKLW H + V A ++SLK L L+Y+DLYLIH+P+ KP
Sbjct: 68 TKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 97.1 bits (231), Expect = 4e-20
Identities = 49/102 (48%), Positives = 64/102 (62%)
Frame = +2
Query: 131 GTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 310
G + S +V +AV AI+AGYRH D A Y +E +VG GI I G V RE+LF+
Sbjct: 8 GLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIA 67
Query: 311 TKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
TKLW H + V A ++SLK L L+Y+DLYLIH+P+ KP
Sbjct: 68 TKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 97.1 bits (231), Expect = 4e-20
Identities = 49/102 (48%), Positives = 64/102 (62%)
Frame = +2
Query: 131 GTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 310
G + S +V +AV AI+AGYRH D A Y +E +VG GI I G V RE+LF+
Sbjct: 8 GLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIA 67
Query: 311 TKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
TKLW H + V A ++SLK L L+Y+DLYLIH+P+ KP
Sbjct: 68 TKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 97.1 bits (231), Expect = 4e-20
Identities = 49/102 (48%), Positives = 64/102 (62%)
Frame = +2
Query: 131 GTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 310
G + S +V +AV AI+AGYRH D A Y +E +VG GI I G V RE+LF+
Sbjct: 8 GLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIA 67
Query: 311 TKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
TKLW H + V A ++SLK L L+Y+DLYLIH+P+ KP
Sbjct: 68 TKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 97.1 bits (231), Expect = 4e-20
Identities = 49/102 (48%), Positives = 64/102 (62%)
Frame = +2
Query: 131 GTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 310
G + S +V +AV AI+AGYRH D A Y +E +VG GI I G V RE+LF+
Sbjct: 8 GLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIA 67
Query: 311 TKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 436
TKLW H + V A ++SLK L L+Y+DLYLIH+P+ KP
Sbjct: 68 TKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
>Y16675-1|CAA76347.1| 330|Homo sapiens aflatoxin B1-aldehyde
reductase protein.
Length = 330
Score = 44.4 bits (100), Expect = 3e-04
Identities = 39/144 (27%), Positives = 64/144 (44%), Gaps = 7/144 (4%)
Frame = +2
Query: 173 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 343
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 88
Query: 344 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 523
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLHQEGKFVELG 140
Query: 524 VSNFNATQITRLV----SNSYIRP 583
+SN+ + ++ + SN +I P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILP 164
>BT007347-1|AAP36011.1| 330|Homo sapiens aldo-keto reductase family
7, member A2 (aflatoxin aldehyde reductase) protein.
Length = 330
Score = 44.4 bits (100), Expect = 3e-04
Identities = 39/144 (27%), Positives = 64/144 (44%), Gaps = 7/144 (4%)
Frame = +2
Query: 173 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 343
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 88
Query: 344 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 523
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLHQEGKFVELG 140
Query: 524 VSNFNATQITRLV----SNSYIRP 583
+SN+ + ++ + SN +I P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILP 164
>BC013996-1|AAH13996.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 44.4 bits (100), Expect = 3e-04
Identities = 39/144 (27%), Positives = 64/144 (44%), Gaps = 7/144 (4%)
Frame = +2
Query: 173 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 343
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 88
Query: 344 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 523
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLHQEGKFVELG 140
Query: 524 VSNFNATQITRLV----SNSYIRP 583
+SN+ + ++ + SN +I P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILP 164
>BC012171-1|AAH12171.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 44.4 bits (100), Expect = 3e-04
Identities = 39/144 (27%), Positives = 64/144 (44%), Gaps = 7/144 (4%)
Frame = +2
Query: 173 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 343
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 88
Query: 344 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 523
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLHQEGKFVELG 140
Query: 524 VSNFNATQITRLV----SNSYIRP 583
+SN+ + ++ + SN +I P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILP 164
>BC011586-1|AAH11586.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 44.4 bits (100), Expect = 3e-04
Identities = 39/144 (27%), Positives = 64/144 (44%), Gaps = 7/144 (4%)
Frame = +2
Query: 173 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 343
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 88
Query: 344 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 523
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLHQEGKFVELG 140
Query: 524 VSNFNATQITRLV----SNSYIRP 583
+SN+ + ++ + SN +I P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILP 164
>BC010852-1|AAH10852.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 44.4 bits (100), Expect = 3e-04
Identities = 39/144 (27%), Positives = 64/144 (44%), Gaps = 7/144 (4%)
Frame = +2
Query: 173 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 343
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 88
Query: 344 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 523
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLHQEGKFVELG 140
Query: 524 VSNFNATQITRLV----SNSYIRP 583
+SN+ + ++ + SN +I P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILP 164
>BC007352-1|AAH07352.2| 358|Homo sapiens AKR7A2 protein protein.
Length = 358
Score = 44.4 bits (100), Expect = 3e-04
Identities = 39/144 (27%), Positives = 64/144 (44%), Gaps = 7/144 (4%)
Frame = +2
Query: 173 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 343
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 58 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 116
Query: 344 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 523
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 117 SVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLHQEGKFVELG 168
Query: 524 VSNFNATQITRLV----SNSYIRP 583
+SN+ + ++ + SN +I P
Sbjct: 169 LSNYASWEVAEICTLCKSNGWILP 192
>BC004111-1|AAH04111.3| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 44.4 bits (100), Expect = 3e-04
Identities = 39/144 (27%), Positives = 64/144 (44%), Gaps = 7/144 (4%)
Frame = +2
Query: 173 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 343
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 88
Query: 344 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 523
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLHQEGKFVELG 140
Query: 524 VSNFNATQITRLV----SNSYIRP 583
+SN+ + ++ + SN +I P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILP 164
>AL035413-8|CAB72321.1| 330|Homo sapiens aldo-keto reductase family
7, member A2 (aflatoxin aldehyde reductase) protein.
Length = 330
Score = 44.4 bits (100), Expect = 3e-04
Identities = 39/144 (27%), Positives = 64/144 (44%), Gaps = 7/144 (4%)
Frame = +2
Query: 173 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 343
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 88
Query: 344 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 523
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLHQEGKFVELG 140
Query: 524 VSNFNATQITRLV----SNSYIRP 583
+SN+ + ++ + SN +I P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILP 164
>AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde
reductase AFAR protein.
Length = 330
Score = 44.4 bits (100), Expect = 3e-04
Identities = 39/144 (27%), Positives = 64/144 (44%), Gaps = 7/144 (4%)
Frame = +2
Query: 173 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 343
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 88
Query: 344 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 523
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHTPDHGTPVE--------ETLHACQRLHQEGKFVELG 140
Query: 524 VSNFNATQITRLV----SNSYIRP 583
+SN+ + ++ + SN +I P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILP 164
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 43.6 bits (98), Expect = 6e-04
Identities = 20/51 (39%), Positives = 31/51 (60%), Gaps = 2/51 (3%)
Frame = +2
Query: 449 DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RPGXNQ 595
D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ + +P NQ
Sbjct: 17 DIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQ 67
>AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto
reductase protein.
Length = 45
Score = 41.1 bits (92), Expect = 0.003
Identities = 19/43 (44%), Positives = 25/43 (58%)
Frame = +2
Query: 317 LWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDS 445
+W + V L+ SLKKL L Y+DLYL HFP+ +P S
Sbjct: 1 VWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPLQPGRS 43
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 39.9 bits (89), Expect = 0.007
Identities = 17/46 (36%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Frame = +2
Query: 470 TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RPGXNQIE 601
TW+ M+ + GL +S+GVSNFN Q+ +++ + +P NQ+E
Sbjct: 28 TWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVE 73
>AF040639-1|AAD02195.1| 331|Homo sapiens aflatoxin B1-aldehyde
reductase protein.
Length = 331
Score = 39.9 bits (89), Expect = 0.007
Identities = 41/144 (28%), Positives = 64/144 (44%), Gaps = 12/144 (8%)
Frame = +2
Query: 188 IEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTRE-----ELFVTTK---LWNDKHARD 343
+E G+ IDTA VY D G +E I GL R + + TK L+ + D
Sbjct: 36 LERGHTEIDTAFVYSD------GQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPD 89
Query: 344 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 523
+ L+ SLK+L +DL+ +H P + P + ET + Q G +G
Sbjct: 90 SLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVE--------ETLRACHQLHQEGKFMELG 141
Query: 524 VSNFNATQITRLV----SNSYIRP 583
+SN+ A ++ + SN +I P
Sbjct: 142 LSNYAAWEVAEICTLCKSNGWILP 165
>BC042420-1|AAH42420.2| 331|Homo sapiens aldo-keto reductase family
7, member A3 (aflatoxin aldehyde reductase) protein.
Length = 331
Score = 38.3 bits (85), Expect = 0.021
Identities = 40/144 (27%), Positives = 64/144 (44%), Gaps = 12/144 (8%)
Frame = +2
Query: 188 IEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTRE-----ELFVTTK---LWNDKHARD 343
+E G+ IDTA VY + G +E I GL R + + TK L+ + D
Sbjct: 36 LERGHTEIDTAFVYSE------GQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPD 89
Query: 344 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 523
+ L+ SLK+L +DL+ +H P + P + ET + Q G +G
Sbjct: 90 SLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVE--------ETLRACHQLHQEGKFMELG 141
Query: 524 VSNFNATQITRLV----SNSYIRP 583
+SN+ A ++ + SN +I P
Sbjct: 142 LSNYAAWEVAEICTLCKSNGWILP 165
>BC031562-1|AAH31562.1| 331|Homo sapiens aldo-keto reductase family
7, member A3 (aflatoxin aldehyde reductase) protein.
Length = 331
Score = 38.3 bits (85), Expect = 0.021
Identities = 40/144 (27%), Positives = 64/144 (44%), Gaps = 12/144 (8%)
Frame = +2
Query: 188 IEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTRE-----ELFVTTK---LWNDKHARD 343
+E G+ IDTA VY + G +E I GL R + + TK L+ + D
Sbjct: 36 LERGHTEIDTAFVYSE------GQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPD 89
Query: 344 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 523
+ L+ SLK+L +DL+ +H P + P + ET + Q G +G
Sbjct: 90 SLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVE--------ETLRACHQLHQEGKFMELG 141
Query: 524 VSNFNATQITRLV----SNSYIRP 583
+SN+ A ++ + SN +I P
Sbjct: 142 LSNYAAWEVAEICTLCKSNGWILP 165
>AJ271799-1|CAC81076.1| 331|Homo sapiens aflatoxin B1 aldehyde
reductase 2 protein.
Length = 331
Score = 38.3 bits (85), Expect = 0.021
Identities = 40/144 (27%), Positives = 64/144 (44%), Gaps = 12/144 (8%)
Frame = +2
Query: 188 IEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTRE-----ELFVTTK---LWNDKHARD 343
+E G+ IDTA VY + G +E I GL R + + TK L+ + D
Sbjct: 36 LERGHTEIDTAFVYSE------GQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPD 89
Query: 344 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 523
+ L+ SLK+L +DL+ +H P + P + ET + Q G +G
Sbjct: 90 SLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVE--------ETLRACHQLHQEGKFMELG 141
Query: 524 VSNFNATQITRLV----SNSYIRP 583
+SN+ A ++ + SN +I P
Sbjct: 142 LSNYAAWEVAEICTLCKSNGWILP 165
>BC025709-1|AAH25709.1| 331|Homo sapiens aldo-keto reductase family
7, member A3 (aflatoxin aldehyde reductase) protein.
Length = 331
Score = 37.5 bits (83), Expect = 0.036
Identities = 40/144 (27%), Positives = 64/144 (44%), Gaps = 12/144 (8%)
Frame = +2
Query: 188 IEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTRE-----ELFVTTK---LWNDKHARD 343
+E G+ IDTA VY + G +E I GL R + + TK L+ + D
Sbjct: 36 LERGHTEIDTAFVYSE------GQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPD 89
Query: 344 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 523
+ L+ SLK+L +DL+ +H P + P + ET + Q G +G
Sbjct: 90 SLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVE--------ETLRACHQLHQEGKFVELG 141
Query: 524 VSNFNATQITRLV----SNSYIRP 583
+SN+ A ++ + SN +I P
Sbjct: 142 LSNYAAWEVAEICTLCKSNGWILP 165
>AL035413-11|CAI22232.1| 331|Homo sapiens aldo-keto reductase
family 7, member A3 (aflatoxin aldehyde reductase)
protein.
Length = 331
Score = 37.5 bits (83), Expect = 0.036
Identities = 40/144 (27%), Positives = 64/144 (44%), Gaps = 12/144 (8%)
Frame = +2
Query: 188 IEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTRE-----ELFVTTK---LWNDKHARD 343
+E G+ IDTA VY + G +E I GL R + + TK L+ + D
Sbjct: 36 LERGHTEIDTAFVYSE------GQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPD 89
Query: 344 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 523
+ L+ SLK+L +DL+ +H P + P + ET + Q G +G
Sbjct: 90 SLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVE--------ETLRACHQLHQEGKFVELG 141
Query: 524 VSNFNATQITRLV----SNSYIRP 583
+SN+ A ++ + SN +I P
Sbjct: 142 LSNYAAWEVAEICTLCKSNGWILP 165
>L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine
synthetase light subunit protein.
Length = 274
Score = 34.7 bits (76), Expect = 0.26
Identities = 25/105 (23%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Frame = +2
Query: 290 REELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYL 466
REE+ V+ KL+ + ++ A+ + LG+ +D +I P D ++++L
Sbjct: 86 REEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVIIASPPIE--DGVNLSLEHL 143
Query: 467 ET-WQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598
+ W+ +++ Q +IG S+ + TQ+ +L + ++P NQ+
Sbjct: 144 QPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein.
Length = 274
Score = 34.7 bits (76), Expect = 0.26
Identities = 25/105 (23%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Frame = +2
Query: 290 REELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYL 466
REE+ V+ KL+ + ++ A+ + LG+ +D +I P D ++++L
Sbjct: 86 REEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVIIASPPIE--DGVNLSLEHL 143
Query: 467 ET-WQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598
+ W+ +++ Q +IG S+ + TQ+ +L + ++P NQ+
Sbjct: 144 QPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 34.7 bits (76), Expect = 0.26
Identities = 25/105 (23%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Frame = +2
Query: 290 REELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYL 466
REE+ V+ KL+ + ++ A+ + LG+ +D +I P D ++++L
Sbjct: 86 REEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVIIASPPIE--DGVNLSLEHL 143
Query: 467 ET-WQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598
+ W+ +++ Q +IG S+ + TQ+ +L + ++P NQ+
Sbjct: 144 QPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 34.7 bits (76), Expect = 0.26
Identities = 25/105 (23%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Frame = +2
Query: 290 REELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYL 466
REE+ V+ KL+ + ++ A+ + LG+ +D +I P D ++++L
Sbjct: 86 REEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVIIASPPIE--DGVNLSLEHL 143
Query: 467 ET-WQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598
+ W+ +++ Q +IG S+ + TQ+ +L + ++P NQ+
Sbjct: 144 QPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine
ligase, modifier subunit protein.
Length = 274
Score = 34.7 bits (76), Expect = 0.26
Identities = 25/105 (23%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Frame = +2
Query: 290 REELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYL 466
REE+ V+ KL+ + ++ A+ + LG+ +D +I P D ++++L
Sbjct: 86 REEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVIIASPPIE--DGVNLSLEHL 143
Query: 467 ET-WQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598
+ W+ +++ Q +IG S+ + TQ+ +L + ++P NQ+
Sbjct: 144 QPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 34.7 bits (76), Expect = 0.26
Identities = 25/105 (23%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Frame = +2
Query: 290 REELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYL 466
REE+ V+ KL+ + ++ A+ + LG+ +D +I P D ++++L
Sbjct: 86 REEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVIIASPPIE--DGVNLSLEHL 143
Query: 467 ET-WQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPGXNQI 598
+ W+ +++ Q +IG S+ + TQ+ +L + ++P NQ+
Sbjct: 144 QPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>AJ278012-1|CAC79668.1| 259|Homo sapiens aflatoxin B1 aldehyde
reductase 3 protein.
Length = 259
Score = 32.3 bits (70), Expect = 1.4
Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 4/85 (4%)
Frame = +2
Query: 341 DQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSI 520
D V L+ SLK+L +DL+ +H P + P + ET + Q G +
Sbjct: 17 DSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVE--------ETLRACHQLHQEGKFVEL 68
Query: 521 GVSNFNATQITRLV----SNSYIRP 583
G+SN+ A ++ + SN +I P
Sbjct: 69 GLSNYAAWEVAEICTLCKSNGWILP 93
>BC117495-1|AAI17496.1| 905|Homo sapiens stonin 2 protein.
Length = 905
Score = 29.9 bits (64), Expect = 7.3
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +2
Query: 218 AAVYQDEEQVGQGIAEAIANGLVTREELFVTTK--LWNDKHARDQVVPALQESLKKLGLD 391
+A ++++E+ Q + + G R+ L V + + D ++ Q E LK+L +D
Sbjct: 332 SAFFEEQERRSQNSSISSTTGKSQRDSLIVIYQDAISFDDSSKTQSHSDAVEKLKQLQID 391
Query: 392 YIDLYLIHFPIATKPDDSP 448
D HF AT PDD P
Sbjct: 392 DPD----HFGSATLPDDDP 406
>BC117493-1|AAI17494.1| 905|Homo sapiens stonin 2 protein.
Length = 905
Score = 29.9 bits (64), Expect = 7.3
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +2
Query: 218 AAVYQDEEQVGQGIAEAIANGLVTREELFVTTK--LWNDKHARDQVVPALQESLKKLGLD 391
+A ++++E+ Q + + G R+ L V + + D ++ Q E LK+L +D
Sbjct: 332 SAFFEEQERRSQNSSISSTTGKSQRDSLIVIYQDAISFDDSSKTQSHSDAVEKLKQLQID 391
Query: 392 YIDLYLIHFPIATKPDDSP 448
D HF AT PDD P
Sbjct: 392 DPD----HFGSATLPDDDP 406
>BC069587-1|AAH69587.1| 904|Homo sapiens STON2 protein protein.
Length = 904
Score = 29.9 bits (64), Expect = 7.3
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +2
Query: 218 AAVYQDEEQVGQGIAEAIANGLVTREELFVTTK--LWNDKHARDQVVPALQESLKKLGLD 391
+A ++++E+ Q + + G R+ L V + + D ++ Q E LK+L +D
Sbjct: 332 SAFFEEQERRSQNSSISSTTGKSQRDSLIVIYQDAISFDDSSKTQSHSDAVEKLKQLQID 391
Query: 392 YIDLYLIHFPIATKPDDSP 448
D HF AT PDD P
Sbjct: 392 DPD----HFGSATLPDDDP 406
>BC069502-1|AAH69502.1| 905|Homo sapiens stonin 2 protein.
Length = 905
Score = 29.9 bits (64), Expect = 7.3
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +2
Query: 218 AAVYQDEEQVGQGIAEAIANGLVTREELFVTTK--LWNDKHARDQVVPALQESLKKLGLD 391
+A ++++E+ Q + + G R+ L V + + D ++ Q E LK+L +D
Sbjct: 332 SAFFEEQERRSQNSSISSTTGKSQRDSLIVIYQDAISFDDSSKTQSHSDAVEKLKQLQID 391
Query: 392 YIDLYLIHFPIATKPDDSP 448
D HF AT PDD P
Sbjct: 392 DPD----HFGSATLPDDDP 406
>BC069389-1|AAH69389.1| 905|Homo sapiens stonin 2 protein.
Length = 905
Score = 29.9 bits (64), Expect = 7.3
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +2
Query: 218 AAVYQDEEQVGQGIAEAIANGLVTREELFVTTK--LWNDKHARDQVVPALQESLKKLGLD 391
+A ++++E+ Q + + G R+ L V + + D ++ Q E LK+L +D
Sbjct: 332 SAFFEEQERRSQNSSISSTTGKSQRDSLIVIYQDAISFDDSSKTQSHSDAVEKLKQLQID 391
Query: 392 YIDLYLIHFPIATKPDDSP 448
D HF AT PDD P
Sbjct: 392 DPD----HFGSATLPDDDP 406
>BC069359-1|AAH69359.1| 905|Homo sapiens stonin 2 protein.
Length = 905
Score = 29.9 bits (64), Expect = 7.3
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +2
Query: 218 AAVYQDEEQVGQGIAEAIANGLVTREELFVTTK--LWNDKHARDQVVPALQESLKKLGLD 391
+A ++++E+ Q + + G R+ L V + + D ++ Q E LK+L +D
Sbjct: 332 SAFFEEQERRSQNSSISSTTGKSQRDSLIVIYQDAISFDDSSKTQSHSDAVEKLKQLQID 391
Query: 392 YIDLYLIHFPIATKPDDSP 448
D HF AT PDD P
Sbjct: 392 DPD----HFGSATLPDDDP 406
>AF449430-1|AAL47008.1| 905|Homo sapiens endocytosis protein HSTNB
variant protein.
Length = 905
Score = 29.9 bits (64), Expect = 7.3
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +2
Query: 218 AAVYQDEEQVGQGIAEAIANGLVTREELFVTTK--LWNDKHARDQVVPALQESLKKLGLD 391
+A ++++E+ Q + + G R+ L V + + D ++ Q E LK+L +D
Sbjct: 332 SAFFEEQERRSQNSSISSTTGKSQRDSLIVIYQDAISFDDSSKTQSHSDAVEKLKQLQID 391
Query: 392 YIDLYLIHFPIATKPDDSP 448
D HF AT PDD P
Sbjct: 392 DPD----HFGSATLPDDDP 406
>AF380833-1|AAK76362.1| 886|Homo sapiens endocytosis protein HSTNB
protein.
Length = 886
Score = 29.9 bits (64), Expect = 7.3
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +2
Query: 218 AAVYQDEEQVGQGIAEAIANGLVTREELFVTTK--LWNDKHARDQVVPALQESLKKLGLD 391
+A ++++E+ Q + + G R+ L V + + D ++ Q E LK+L +D
Sbjct: 313 SAFFEEQERRSQNSSISSTTGKSQRDSLIVIYQDAISFDDSSKTQSHSDAVEKLKQLQID 372
Query: 392 YIDLYLIHFPIATKPDDSP 448
D HF AT PDD P
Sbjct: 373 DPD----HFGSATLPDDDP 387
>AF255309-1|AAK57558.1| 702|Homo sapiens stonin 2 protein.
Length = 702
Score = 29.9 bits (64), Expect = 7.3
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +2
Query: 218 AAVYQDEEQVGQGIAEAIANGLVTREELFVTTK--LWNDKHARDQVVPALQESLKKLGLD 391
+A ++++E+ Q + + G R+ L V + + D ++ Q E LK+L +D
Sbjct: 129 SAFFEEQERRSQNSSISSTTGKSQRDSLIVIYQDAISFDDSSKTQSHSDAVEKLKQLQID 188
Query: 392 YIDLYLIHFPIATKPDDSP 448
D HF AT PDD P
Sbjct: 189 DPD----HFGSATLPDDDP 203
>AB208948-1|BAD92185.1| 932|Homo sapiens Stonin 2 variant protein.
Length = 932
Score = 29.9 bits (64), Expect = 7.3
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +2
Query: 218 AAVYQDEEQVGQGIAEAIANGLVTREELFVTTK--LWNDKHARDQVVPALQESLKKLGLD 391
+A ++++E+ Q + + G R+ L V + + D ++ Q E LK+L +D
Sbjct: 344 SAFFEEQERRSQNSSISSTTGKSQRDSLIVIYQDAISFDDSSKTQSHSDAVEKLKQLQID 403
Query: 392 YIDLYLIHFPIATKPDDSP 448
D HF AT PDD P
Sbjct: 404 DPD----HFGSATLPDDDP 418
>M80469-1|AAA36307.1| 28|Homo sapiens MHC class I HLA-J antigen
protein.
Length = 28
Score = 29.5 bits (63), Expect = 9.6
Identities = 11/24 (45%), Positives = 14/24 (58%), Gaps = 1/24 (4%)
Frame = +3
Query: 465 WKPG-KACRTRGSWVWPGPLEYPT 533
W+P +C +RG W WP P PT
Sbjct: 4 WRPEPSSCCSRGPWPWPRPGRAPT 27
>M80468-1|AAA36306.1| 28|Homo sapiens MHC class I HLA-J antigen
protein.
Length = 28
Score = 29.5 bits (63), Expect = 9.6
Identities = 11/24 (45%), Positives = 14/24 (58%), Gaps = 1/24 (4%)
Frame = +3
Query: 465 WKPG-KACRTRGSWVWPGPLEYPT 533
W+P +C +RG W WP P PT
Sbjct: 4 WRPEPSSCCSRGPWPWPRPGRAPT 27
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 92,211,635
Number of Sequences: 237096
Number of extensions: 1875139
Number of successful extensions: 4324
Number of sequences better than 10.0: 128
Number of HSP's better than 10.0 without gapping: 4047
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4157
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6410414940
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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