Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= epV31077
(723 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M19713-1|AAA61225.1| 284|Homo sapiens TPM1 protein. 214 2e-55
AY640415-1|AAT68295.1| 284|Homo sapiens tropomyosin alpha stria... 214 3e-55
X06825-1|CAA29971.1| 284|Homo sapiens protein ( Human mRNA for ... 211 2e-54
AL133410-4|CAI10977.1| 284|Homo sapiens tropomyosin 2 (beta) pr... 211 2e-54
AL133410-3|CAI10976.1| 322|Homo sapiens tropomyosin 2 (beta) pr... 211 2e-54
AL133410-1|CAI10975.1| 284|Homo sapiens tropomyosin 2 (beta) pr... 211 2e-54
X04201-1|CAA27798.1| 285|Homo sapiens protein ( Human skeletal ... 210 5e-54
BC008425-1|AAH08425.1| 285|Homo sapiens tropomyosin 3 protein. 210 5e-54
BC008407-1|AAH08407.1| 285|Homo sapiens tropomyosin 3 protein. 210 5e-54
AL590431-12|CAH71269.1| 284|Homo sapiens tropomyosin 3 protein. 210 5e-54
AK023385-1|BAB14554.1| 284|Homo sapiens protein ( Homo sapiens ... 207 4e-53
M19267-1|AAA36771.1| 284|Homo sapiens protein ( Human tropomyos... 205 1e-52
BC007433-1|AAH07433.1| 284|Homo sapiens tropomyosin 1 (alpha) p... 205 1e-52
M75165-1|AAB59509.1| 284|Homo sapiens tropomyosin protein. 204 2e-52
M74817-1|AAA61230.1| 284|Homo sapiens tropomyosin-1 protein. 204 2e-52
M12125-1|AAA36773.1| 284|Homo sapiens protein ( Human fibroblas... 204 2e-52
BC011776-1|AAH11776.1| 284|Homo sapiens tropomyosin 2 (beta) pr... 204 2e-52
AL133410-2|CAI10974.1| 284|Homo sapiens tropomyosin 2 (beta) pr... 204 2e-52
AF209746-1|AAF17621.1| 257|Homo sapiens beta tropomyosin protein. 204 2e-52
AK223258-1|BAD96978.1| 284|Homo sapiens tropomyosin 2 (beta) is... 202 8e-52
AY640414-1|AAT68294.1| 284|Homo sapiens sarcomeric tropomyosin ... 198 2e-50
AK131384-1|BAD18535.1| 326|Homo sapiens protein ( Homo sapiens ... 185 1e-46
M19714-1|AAA61226.1| 264|Homo sapiens TPM1 protein. 182 2e-45
BC053545-1|AAH53545.1| 245|Homo sapiens tropomyosin 1 (alpha) p... 159 7e-39
BC050473-1|AAH50473.1| 287|Homo sapiens TPM1 protein protein. 159 7e-39
AB209041-1|BAD92278.1| 303|Homo sapiens TPM1 protein variant pr... 157 5e-38
AL590431-10|CAH71268.1| 247|Homo sapiens tropomyosin 3 protein. 156 9e-38
AL590431-9|CAH71267.1| 248|Homo sapiens tropomyosin 3 protein. 156 9e-38
Z24727-1|CAA80853.1| 243|Homo sapiens tropomyosin isoform protein. 155 2e-37
M19715-1|AAA61227.1| 229|Homo sapiens TPM1 protein. 153 6e-37
X05276-1|CAA28888.1| 248|Homo sapiens protein ( Human mRNA for ... 151 2e-36
BT019634-1|AAV38440.1| 248|Homo sapiens tropomyosin 4 protein. 151 2e-36
BC067225-1|AAH67225.1| 248|Homo sapiens tropomyosin 4 protein. 151 2e-36
BC037576-1|AAH37576.1| 248|Homo sapiens tropomyosin 4 protein. 151 2e-36
AF310722-1|AAK17926.1| 320|Homo sapiens tropomyosin 4-anaplasti... 151 2e-36
AF186109-1|AAG17014.1| 237|Homo sapiens TPM4-ALK fusion oncopro... 151 2e-36
DQ424903-1|ABD83668.1| 245|Homo sapiens tropomyosin 1 alpha var... 151 3e-36
BC002827-1|AAH02827.1| 248|Homo sapiens tropomyosin 4 protein. 150 4e-36
AL590431-11|CAH71270.1| 242|Homo sapiens tropomyosin 3 protein. 149 1e-35
AK092690-1|BAC03946.1| 243|Homo sapiens protein ( Homo sapiens ... 149 1e-35
AF474156-1|AAL84569.1| 203|Homo sapiens TPMsk1 protein. 149 1e-35
X04588-1|CAB37185.1| 248|Homo sapiens protein ( Human 2.5 kb mR... 144 2e-34
BC072428-1|AAH72428.1| 248|Homo sapiens tropomyosin 3 protein. 144 2e-34
BC015403-1|AAH15403.1| 248|Homo sapiens tropomyosin 3 protein. 144 2e-34
BC000771-1|AAH00771.1| 248|Homo sapiens tropomyosin 3 protein. 144 2e-34
AY004867-1|AAF87083.1| 247|Homo sapiens tropomyosin isoform pro... 144 2e-34
AL590431-8|CAH71264.1| 248|Homo sapiens tropomyosin 3 protein. 144 2e-34
AL590431-7|CAH71266.1| 248|Homo sapiens tropomyosin 3 protein. 144 2e-34
AF474157-1|AAL84570.1| 247|Homo sapiens TPMsk3 protein. 144 2e-34
X12369-1|CAA30930.1| 227|Homo sapiens tropomyosin (227 AA) prot... 143 5e-34
X03541-1|CAA27243.1| 641|Homo sapiens protein ( Human mRNA of t... 143 7e-34
DQ120714-1|ABC40673.1| 247|Homo sapiens rcTPM3 protein. 139 1e-32
AK129882-1|BAC85248.1| 217|Homo sapiens protein ( Homo sapiens ... 134 3e-31
AL590431-5|CAH71263.1| 224|Homo sapiens tropomyosin 3 protein. 115 2e-25
AL590431-6|CAH71265.1| 232|Homo sapiens tropomyosin 3 protein. 109 1e-23
BC062740-1|AAH62740.1| 158|Homo sapiens TPM3 protein protein. 97 4e-20
AL590431-4|CAH71262.1| 158|Homo sapiens tropomyosin 3 protein. 97 4e-20
AL590431-3|CAH71261.1| 158|Homo sapiens tropomyosin 3 protein. 97 4e-20
AF186110-1|AAG17015.1| 227|Homo sapiens TPM4-ALK fusion oncopro... 96 1e-19
AK092712-1|BAC03956.1| 183|Homo sapiens protein ( Homo sapiens ... 76 1e-13
BX537964-1|CAD97928.1| 898|Homo sapiens hypothetical protein pr... 69 1e-11
BC105632-1|AAI05633.1| 898|Homo sapiens chromosome 10 open read... 69 1e-11
BC103499-1|AAI03500.1| 898|Homo sapiens chromosome 10 open read... 69 1e-11
BC100670-1|AAI00671.1| 1004|Homo sapiens C10orf118 protein protein. 69 1e-11
AF273054-1|AAM44457.1| 613|Homo sapiens CTCL tumor antigen HD-C... 69 1e-11
M12127-1|AAA36774.1| 131|Homo sapiens protein ( Human cytoskele... 69 2e-11
M12126-1|AAA61229.1| 131|Homo sapiens TPM2 protein. 67 7e-11
S73840-1|AAC13916.1| 231|Homo sapiens type IIA myosin heavy cha... 63 1e-09
BC129821-1|AAI29822.1| 315|Homo sapiens FLJ36144 protein protein. 63 1e-09
BC126409-1|AAI26410.1| 1941|Homo sapiens myosin, heavy chain 2, ... 63 1e-09
AF111784-1|AAD29950.1| 1941|Homo sapiens myosin heavy chain IIa ... 63 1e-09
M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein. 62 1e-09
BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,... 62 1e-09
BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,... 62 1e-09
BC000280-1|AAH00280.1| 471|Homo sapiens MYH10 protein protein. 62 1e-09
AK097432-1|BAC05050.1| 466|Homo sapiens protein ( Homo sapiens ... 62 1e-09
AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein p... 62 1e-09
X13939-1|CAA32122.1| 328|Homo sapiens laminin B2 protein. 62 2e-09
X03740-1|CAA27380.1| 876|Homo sapiens protein ( Human skeletal ... 62 2e-09
M55210-1|AAA59492.1| 1609|Homo sapiens laminin B2 chain protein. 62 2e-09
M27654-1|AAA59489.1| 217|Homo sapiens laminin B2 protein. 62 2e-09
J03202-1|AAA59488.1| 1609|Homo sapiens LAMB2 protein. 62 2e-09
AL450304-5|CAI14877.1| 1609|Homo sapiens laminin, gamma 1 (forme... 62 2e-09
AL354953-3|CAH70981.1| 1609|Homo sapiens laminin, gamma 1 (forme... 62 2e-09
Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein. 62 3e-09
X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain ... 62 3e-09
BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1, ... 62 3e-09
AK093463-1|BAC04173.1| 650|Homo sapiens protein ( Homo sapiens ... 62 3e-09
AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/... 62 3e-09
X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein. 61 3e-09
U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein. 61 3e-09
U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein. 61 3e-09
X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy ch... 61 5e-09
X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mR... 61 5e-09
X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for ... 61 5e-09
X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 ... 61 5e-09
M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy ch... 61 5e-09
BC118982-1|AAI18983.1| 553|Homo sapiens KIAA2012 protein protein. 61 5e-09
AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein. 61 5e-09
AY517555-1|AAT44528.1| 941|Homo sapiens hypothetical rhabdomyos... 61 5e-09
AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain prot... 61 5e-09
AB095932-1|BAC23108.1| 555|Homo sapiens KIAA2012 protein protein. 61 5e-09
D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heav... 60 6e-09
BC146779-1|AAI46780.1| 1669|Homo sapiens intersectin 2 protein. 60 6e-09
BC127816-1|AAI27817.1| 416|Homo sapiens Unknown (protein for IM... 60 6e-09
AK097517-1|BAC05084.1| 621|Homo sapiens protein ( Homo sapiens ... 60 6e-09
AK021545-1|BAB13841.1| 436|Homo sapiens protein ( Homo sapiens ... 60 6e-09
AF248540-1|AAF63600.1| 1681|Homo sapiens intersectin 2 protein. 60 6e-09
AF182199-1|AAF59904.1| 1248|Homo sapiens intersectin 2 short iso... 60 6e-09
AF182198-1|AAF59903.1| 1696|Homo sapiens intersectin 2 long isof... 60 6e-09
AF111783-1|AAD29949.1| 1939|Homo sapiens myosin heavy chain IIb ... 60 6e-09
AC009228-1|AAX93122.1| 1329|Homo sapiens unknown protein. 60 6e-09
AB033082-1|BAA86570.1| 1676|Homo sapiens KIAA1256 protein protein. 60 6e-09
Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heav... 60 8e-09
BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6, ... 60 8e-09
Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9, no... 60 1e-08
M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle... 60 1e-08
CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein. 60 1e-08
AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein pr... 60 1e-08
AK131080-1|BAC85130.1| 563|Homo sapiens FLJ00279 protein protein. 60 1e-08
AK092490-1|BAC03904.1| 280|Homo sapiens protein ( Homo sapiens ... 60 1e-08
AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy... 60 1e-08
Z97054-3|CAI42646.1| 1233|Homo sapiens structural maintenance of... 58 2e-08
X64838-1|CAA46050.1| 1427|Homo sapiens restin protein. 58 2e-08
S78271-1|AAB34405.1| 1233|Homo sapiens SB1.8/DXS423E protein. 58 2e-08
M97501-1|AAA35693.1| 1392|Homo sapiens cytoplasmic linker protei... 58 2e-08
D80000-1|BAA11495.2| 1233|Homo sapiens KIAA0178 protein. 58 2e-08
BC126305-1|AAI26306.1| 1438|Homo sapiens CLIP1 protein protein. 58 2e-08
BC114213-1|AAI14214.1| 1392|Homo sapiens CAP-GLY domain containi... 58 2e-08
BC112127-1|AAI12128.1| 1233|Homo sapiens SMC1 structural mainten... 58 2e-08
BC064368-1|AAH64368.1| 847|Homo sapiens SMC1A protein protein. 58 2e-08
AL161779-1|CAI42089.1| 1233|Homo sapiens structural maintenance ... 58 2e-08
BC117209-1|AAI17210.1| 1438|Homo sapiens CLIP1 protein protein. 58 3e-08
X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein. 58 4e-08
Z29064-1|CAA82305.1| 896|Homo sapiens AF-1p protein. 57 6e-08
Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein. 57 6e-08
U07707-1|AAA52101.1| 896|Homo sapiens epidermal growth factor r... 57 6e-08
DQ367924-1|ABD34786.1| 896|Homo sapiens epidermal growth factor... 57 6e-08
AL671986-11|CAI13030.1| 896|Homo sapiens epidermal growth facto... 57 6e-08
AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein p... 57 6e-08
U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein. 57 7e-08
U19769-1|AAA82889.1| 3210|Homo sapiens CENP-F kinetochore protei... 57 7e-08
L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated prote... 57 7e-08
AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting cit... 57 7e-08
AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F, 3... 57 7e-08
AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F, 3... 57 7e-08
AF200415-1|AAF08305.2| 1825|Homo sapiens proliferation-related p... 57 7e-08
X97053-1|CAA65765.1| 566|Homo sapiens plectin protein. 56 1e-07
X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin he... 56 1e-07
U63610-1|AAB05428.1| 4574|Homo sapiens plectin protein. 56 1e-07
U53204-1|AAB05427.1| 4574|Homo sapiens plectin protein. 56 1e-07
BC112391-1|AAI12392.1| 957|Homo sapiens ELKS/RAB6-interacting/C... 56 1e-07
BC111550-1|AAI11551.1| 957|Homo sapiens ERC2 protein protein. 56 1e-07
BC101520-1|AAI01521.1| 1194|Homo sapiens protein tyrosine phosph... 56 1e-07
BC101518-1|AAI01519.1| 1194|Homo sapiens protein tyrosine phosph... 56 1e-07
AB209115-1|BAD92352.1| 1065|Homo sapiens restin isoform a varian... 56 1e-07
AB014554-1|BAA31629.2| 1267|Homo sapiens KIAA0654 protein protein. 56 1e-07
AB002376-1|BAA20832.2| 970|Homo sapiens KIAA0378 protein. 56 1e-07
U25725-1|AAA86889.1| 1017|Homo sapiens AH antigen protein. 56 1e-07
BC132736-1|AAI32737.1| 1843|Homo sapiens coiled-coil domain cont... 56 1e-07
AY480051-1|AAR95684.1| 4547|Homo sapiens plectin 11 protein. 56 1e-07
AY480050-1|AAR95683.1| 4551|Homo sapiens plectin 10 protein. 56 1e-07
AY480049-1|AAR95682.1| 4547|Homo sapiens plectin 8 protein. 56 1e-07
AY480048-1|AAR95681.1| 4515|Homo sapiens plectin 7 protein. 56 1e-07
AY480047-1|AAR95680.1| 4684|Homo sapiens plectin 6 protein. 56 1e-07
AY480046-1|AAR95679.1| 4525|Homo sapiens plectin 3 protein. 56 1e-07
AY480045-1|AAR95678.1| 4533|Homo sapiens plectin 2 protein. 56 1e-07
AY480044-1|AAR95677.1| 4574|Homo sapiens plectin 1 protein. 56 1e-07
AF362887-1|AAK51964.1| 142|Homo sapiens tropomyosin 4-anaplasti... 56 1e-07
AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein. 56 1e-07
AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein... 56 1e-07
Z75311-1|CAA99729.1| 1318|Homo sapiens RAD50 homologue hsRAD50 p... 56 2e-07
X03741-1|CAA27381.1| 635|Homo sapiens protein ( Human cardiac m... 56 2e-07
D86970-1|BAA13206.2| 2067|Homo sapiens KIAA0216 protein. 56 2e-07
D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heav... 56 2e-07
BC142716-1|AAI42717.1| 601|Homo sapiens EPS15L1 protein protein. 56 2e-07
BC142662-1|AAI42663.1| 600|Homo sapiens EPS15L1 protein protein. 56 2e-07
BC131590-1|AAI31591.1| 754|Homo sapiens EPS15L1 protein protein. 56 2e-07
BC104912-1|AAI04913.1| 1236|Homo sapiens PPFIA2 protein protein. 56 2e-07
BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,... 56 2e-07
BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,... 56 2e-07
BC080545-1|AAH80545.1| 498|Homo sapiens MYH11 protein protein. 56 2e-07
BC039612-1|AAH39612.1| 2002|Homo sapiens MYO18A protein protein. 56 2e-07
BC020921-1|AAH20921.1| 560|Homo sapiens ITSN2 protein protein. 56 2e-07
AY703984-1|AAV80770.1| 1581|Homo sapiens SP-A receptor subunit S... 56 2e-07
AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin he... 56 2e-07
AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin he... 56 2e-07
AL832636-1|CAD89951.1| 546|Homo sapiens hypothetical protein pr... 56 2e-07
AF110265-1|AAF21930.1| 864|Homo sapiens epidermal growth factor... 56 2e-07
AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin he... 56 2e-07
AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin he... 56 2e-07
AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY... 56 2e-07
AB210009-1|BAE06091.1| 1258|Homo sapiens PPFIA2 variant protein ... 56 2e-07
AB177860-1|BAD66838.1| 1715|Homo sapiens KIAA0216 splice variant... 56 2e-07
AB177858-1|BAD66836.1| 2046|Homo sapiens KIAA0216 splice variant... 56 2e-07
AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein. 56 2e-07
AB015346-1|BAA88118.1| 864|Homo sapiens Eps15R protein. 56 2e-07
Z98946-1|CAB46379.1| 577|Homo sapiens moesin protein. 55 2e-07
U80458-1|AAD00355.1| 1604|Homo sapiens microtubule associated pr... 55 2e-07
M69066-1|AAA36322.1| 577|Homo sapiens moesin B protein. 55 2e-07
M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain p... 55 2e-07
M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain p... 55 2e-07
EF560725-1|ABQ59035.1| 1934|Homo sapiens MYH7 protein protein. 55 2e-07
EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7, ... 55 2e-07
BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7, ... 55 2e-07
BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7, ... 55 2e-07
BC028423-1|AAH28423.1| 1022|Homo sapiens PMFBP1 protein protein. 55 2e-07
BC017293-1|AAH17293.1| 577|Homo sapiens moesin protein. 55 2e-07
AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antige... 55 2e-07
AK093285-1|BAC04121.1| 797|Homo sapiens protein ( Homo sapiens ... 55 2e-07
AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain... 55 2e-07
AF034799-1|AAC26100.1| 1257|Homo sapiens liprin-alpha2 protein. 55 2e-07
AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypepti... 55 2e-07
X52889-1|CAA37068.1| 1934|Homo sapiens cardiac beta myosin heavy... 55 3e-07
X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain (... 55 3e-07
BC129803-1|AAI29804.1| 638|Homo sapiens MYH14 protein protein. 54 4e-07
BC103824-1|AAI03825.1| 546|Homo sapiens taxilin alpha protein. 54 4e-07
BC103823-1|AAI03824.1| 546|Homo sapiens taxilin alpha protein. 54 4e-07
BC080578-1|AAH80578.1| 546|Homo sapiens taxilin alpha protein. 54 4e-07
BC000676-1|AAH00676.2| 483|Homo sapiens MYH14 protein protein. 54 4e-07
AY359522-1|AAQ57128.1| 657|Homo sapiens hypothetical protein DK... 54 4e-07
AY165122-1|AAO39147.1| 1995|Homo sapiens myosin heavy chain prot... 54 4e-07
AL834265-1|CAD38940.1| 505|Homo sapiens hypothetical protein pr... 54 4e-07
AL445928-1|CAH72248.1| 657|Homo sapiens novel protein protein. 54 4e-07
AL049795-2|CAI22055.1| 546|Homo sapiens novel protein protein. 54 4e-07
AK023943-1|BAB14735.1| 545|Homo sapiens protein ( Homo sapiens ... 54 4e-07
AF516206-1|AAO42465.1| 546|Homo sapiens taxilin protein. 54 4e-07
AB111886-1|BAC98374.1| 1571|Homo sapiens KIAA2034 protein protein. 54 4e-07
X06976-1|CAA30039.1| 543|Homo sapiens beta myosin heavy chain (... 54 5e-07
U22816-1|AAC50173.1| 1202|Homo sapiens LAR-interacting protein 1... 54 5e-07
U22815-1|AAC50172.1| 1185|Homo sapiens LAR-interacting protein 1... 54 5e-07
M25139-1|AAA60385.1| 611|Homo sapiens myosin heavy chain beta-s... 54 5e-07
M21665-1|AAA36345.1| 524|Homo sapiens protein ( Human beta-myos... 54 5e-07
M17712-1|AAA36343.1| 543|Homo sapiens protein ( Human cardiac m... 54 5e-07
D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein. 54 5e-07
BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 54 5e-07
BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 54 5e-07
BC101026-1|AAI01027.1| 490|Homo sapiens SASS6 protein protein. 54 5e-07
BC034046-1|AAH34046.1| 1202|Homo sapiens protein tyrosine phosph... 54 5e-07
AL121586-7|CAB89415.1| 2442|Homo sapiens centrosomal protein 250... 54 5e-07
AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal Nek2-associ... 54 5e-07
AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome assoc... 54 5e-07
AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein. 54 5e-07
AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein. 54 5e-07
AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein. 54 5e-07
DQ139275-1|ABA43896.1| 1313|Homo sapiens Tax1-binding protein 2 ... 54 7e-07
BX284668-3|CAH70057.1| 1898|Homo sapiens ciliary rootlet coiled-... 54 7e-07
BX284668-2|CAH70055.1| 2017|Homo sapiens ciliary rootlet coiled-... 54 7e-07
AL049569-4|CAI20365.1| 1898|Homo sapiens ciliary rootlet coiled-... 54 7e-07
AL049569-3|CAI20363.1| 2017|Homo sapiens ciliary rootlet coiled-... 54 7e-07
AB023217-1|BAA76844.2| 1956|Homo sapiens KIAA1000 protein protein. 54 7e-07
AB007914-1|BAA32290.2| 1919|Homo sapiens KIAA0445 protein protein. 54 7e-07
U63139-1|AAB07119.1| 1312|Homo sapiens Rad50 protein. 53 9e-07
M21664-1|AAA36344.1| 532|Homo sapiens protein ( Human alpha-myo... 53 9e-07
L02320-1|AAA36541.1| 583|Homo sapiens radixin protein. 53 9e-07
BC146789-1|AAI46790.1| 1583|Homo sapiens GRIP and coiled-coil do... 53 9e-07
BC091490-1|AAH91490.1| 620|Homo sapiens ODF2L protein protein. 53 9e-07
AF057300-1|AAD50326.1| 1173|Homo sapiens truncated RAD50 protein... 53 9e-07
AF057299-1|AAD50325.1| 1312|Homo sapiens RAD50-2 protein protein. 53 9e-07
AC012487-1|AAX88838.1| 1583|Homo sapiens unknown protein. 53 9e-07
AB033102-1|BAA86590.1| 1068|Homo sapiens KIAA1276 protein protein. 53 9e-07
AB002334-1|BAA20794.2| 1635|Homo sapiens KIAA0336 protein. 53 9e-07
Z11584-1|CAA77670.1| 2101|Homo sapiens NuMA protein protein. 53 1e-06
Z11583-1|CAA77669.1| 2115|Homo sapiens NuMA protein protein. 53 1e-06
AB210007-1|BAE06089.1| 2121|Homo sapiens NUMA1 variant protein p... 53 1e-06
AB208841-1|BAD92078.1| 1585|Homo sapiens Nuclear mitotic apparat... 53 1e-06
Z54367-1|CAA91196.1| 4684|Homo sapiens plectin protein. 52 2e-06
U38292-1|AAB41133.1| 2805|Homo sapiens microtubule-associated pr... 52 2e-06
U38291-1|AAB41132.1| 2805|Homo sapiens microtubule-associated pr... 52 2e-06
S67240-1|AAB28951.1| 330|Homo sapiens smooth muscle myosin heav... 52 2e-06
S67238-1|AAB28950.1| 296|Homo sapiens smooth muscle myosin heav... 52 2e-06
BC046212-1|AAH46212.1| 364|Homo sapiens Similar to cytomatrix p... 52 2e-06
BC029425-1|AAH29425.1| 272|Homo sapiens Unknown (protein for IM... 52 2e-06
AL451082-2|CAH72276.1| 1194|Homo sapiens protein tyrosine phosph... 52 2e-06
AL365436-3|CAI16590.1| 1203|Homo sapiens cingulin protein. 52 2e-06
AK097021-1|BAC04928.1| 512|Homo sapiens protein ( Homo sapiens ... 52 2e-06
AF263462-1|AAF74498.1| 1203|Homo sapiens cingulin protein. 52 2e-06
AB037740-1|BAA92557.1| 1208|Homo sapiens KIAA1319 protein protein. 52 2e-06
Z22551-1|CAA80271.1| 1356|Homo sapiens 156 kDa Protein protein. 52 2e-06
X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein. 52 2e-06
L25616-1|AAB65853.1| 1300|Homo sapiens kinectin protein. 52 2e-06
D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372 prot... 52 2e-06
D13629-1|BAA02794.2| 1307|Homo sapiens KIAA0004 protein. 52 2e-06
BC117132-1|AAI17133.1| 1306|Homo sapiens kinectin 1 (kinesin rec... 52 2e-06
BC112337-1|AAI12338.1| 1306|Homo sapiens kinectin 1 (kinesin rec... 52 2e-06
BC078168-1|AAH78168.1| 887|Homo sapiens CCDC88A protein protein. 52 2e-06
BC050555-1|AAH50555.1| 873|Homo sapiens KTN1 protein protein. 52 2e-06
AY536375-1|AAT66048.1| 820|Homo sapiens rhabdomyosarcoma antige... 52 2e-06
AY264265-1|AAP20418.1| 1357|Homo sapiens kinectin variant 1 prot... 52 2e-06
AK131470-1|BAD18615.1| 458|Homo sapiens protein ( Homo sapiens ... 52 2e-06
AC002563-2|AAB71327.1| 1286|Homo sapiens WUGSC:H_127H14.1 protein. 52 2e-06
AB023166-1|BAA76793.2| 1559|Homo sapiens KIAA0949 protein protein. 52 2e-06
Z22664-1|CAA80377.1| 595|Homo sapiens membrane organizing prote... 52 3e-06
Y18000-2|CAA76993.1| 615|Homo sapiens NF2 protein protein. 52 3e-06
Y18000-1|CAA76992.1| 595|Homo sapiens NF2 protein protein. 52 3e-06
X72655-1|CAA51220.1| 595|Homo sapiens schwannomin protein. 52 3e-06
X66397-1|CAA47021.1| 2349|Homo sapiens Tpr protein. 52 3e-06
U69668-1|AAB48030.1| 2363|Homo sapiens Tpr protein. 52 3e-06
L11353-1|AAA36212.1| 595|Homo sapiens moesin-ezrin-radixin-like... 52 3e-06
CR456530-1|CAG30416.1| 595|Homo sapiens NF2 protein. 52 3e-06
BC151242-1|AAI51243.1| 1983|Homo sapiens myosin, heavy chain 7B,... 52 3e-06
BC114620-1|AAI14621.1| 1756|Homo sapiens periplakin protein. 52 3e-06
BC047109-1|AAH47109.1| 583|Homo sapiens radixin protein. 52 3e-06
BC020257-1|AAH20257.1| 595|Homo sapiens neurofibromin 2 (bilate... 52 3e-06
BC003112-1|AAH03112.2| 507|Homo sapiens neurofibromin 2 (bilate... 52 3e-06
AL596220-1|CAI13119.1| 2363|Homo sapiens translocated promoter r... 52 3e-06
AL133553-3|CAI17859.1| 2363|Homo sapiens translocated promoter r... 52 3e-06
AL133324-2|CAI19310.2| 1983|Homo sapiens myosin, heavy chain 7B,... 52 3e-06
AL132825-6|CAI43047.2| 1983|Homo sapiens myosin, heavy chain 7B,... 52 3e-06
AF369701-1|AAK54196.1| 590|Homo sapiens neurofibromatosis type ... 52 3e-06
AF369665-1|AAK54166.1| 507|Homo sapiens neurofibromatosis type ... 52 3e-06
AF369664-1|AAK54165.1| 549|Homo sapiens neurofibromatosis type ... 52 3e-06
AF369663-1|AAK54164.1| 548|Homo sapiens neurofibromatosis type ... 52 3e-06
AF369662-1|AAK54163.1| 590|Homo sapiens neurofibromatosis type ... 52 3e-06
AF369661-1|AAK54162.1| 595|Homo sapiens neurofibromatosis type ... 52 3e-06
AF369658-1|AAK54161.1| 590|Homo sapiens neurofibromatosis type ... 52 3e-06
AF369657-1|AAK54160.1| 595|Homo sapiens neurofibromatosis type ... 52 3e-06
AF041004-1|AAD17459.1| 1756|Homo sapiens periplakin protein. 52 3e-06
AF013717-1|AAC39668.1| 1756|Homo sapiens periplakin protein. 52 3e-06
AF001691-1|AAC17738.1| 1756|Homo sapiens 195 kDa cornified envel... 52 3e-06
AB040945-1|BAA96036.2| 2010|Homo sapiens KIAA1512 protein protein. 52 3e-06
AB011140-1|BAA25494.1| 1426|Homo sapiens KIAA0568 protein protein. 52 3e-06
M81105-1|AAA59888.1| 1337|Homo sapiens cellular myosin heavy cha... 51 4e-06
BC049849-1|AAH49849.1| 1374|Homo sapiens MYH9 protein protein. 51 4e-06
BC006984-1|AAH06984.1| 512|Homo sapiens Unknown (protein for IM... 51 4e-06
AL832637-1|CAD89952.1| 546|Homo sapiens hypothetical protein pr... 51 4e-06
X58677-1|CAA41528.1| 608|Homo sapiens hemidesmosomal plaque pr... 51 5e-06
M63618-1|AAA35606.1| 2095|Homo sapiens bullous pemphigoid antige... 51 5e-06
M61951-1|AAA59486.1| 1786|Homo sapiens laminin B1 protein. 51 5e-06
M61916-1|AAA59482.1| 1786|Homo sapiens laminin B1 protein. 51 5e-06
M55370-1|AAA59485.1| 1786|Homo sapiens laminin B1 protein. 51 5e-06
L11690-1|AAA52288.1| 2649|Homo sapiens bullous pemphigoid antige... 51 5e-06
BC131515-1|AAI31516.1| 632|Homo sapiens GOLGA6 protein protein. 51 5e-06
BC113455-1|AAI13456.1| 1786|Homo sapiens laminin, beta 1 protein. 51 5e-06
BC109126-1|AAI09127.1| 872|Homo sapiens chromosome 10 open read... 51 5e-06
BC036225-1|AAH36225.1| 872|Homo sapiens chromosome 10 open read... 51 5e-06
BC026018-1|AAH26018.2| 1083|Homo sapiens LAMB1 protein protein. 51 5e-06
BC000616-1|AAH00616.1| 585|Homo sapiens SWAP-70 protein protein. 51 5e-06
AL355378-1|CAI15667.1| 872|Homo sapiens novel protein protein. 51 5e-06
AL162742-5|CAI12110.1| 872|Homo sapiens novel protein protein. 51 5e-06
AL096710-6|CAI22047.1| 2649|Homo sapiens dystonin protein. 51 5e-06
AK125925-1|BAC86346.1| 623|Homo sapiens protein ( Homo sapiens ... 51 5e-06
AK093227-1|BAC04102.1| 550|Homo sapiens protein ( Homo sapiens ... 51 5e-06
AF266285-1|AAF72535.1| 693|Homo sapiens golgin-like protein pro... 51 5e-06
AF263742-1|AAF72196.1| 693|Homo sapiens golgin-like protein pro... 51 5e-06
AF210818-1|AAF24486.1| 585|Homo sapiens SWAP-70 protein. 51 5e-06
AF134894-1|AAF61403.1| 585|Homo sapiens SWAP-70 homolog protein. 51 5e-06
AB051536-1|BAB21840.2| 1047|Homo sapiens KIAA1749 protein protein. 51 5e-06
AB014540-1|BAA31615.1| 603|Homo sapiens KIAA0640 protein protein. 51 5e-06
L01042-1|AAD54608.1| 1093|Homo sapiens TATA element modulatory f... 50 6e-06
BC150248-1|AAI50249.1| 992|Homo sapiens ELKS/RAB6-interacting/C... 50 6e-06
BC126123-1|AAI26124.1| 1093|Homo sapiens TATA element modulatory... 50 6e-06
BC117418-1|AAI17419.1| 1093|Homo sapiens TATA element modulatory... 50 6e-06
BC009941-1|AAH09941.1| 550|Homo sapiens coiled-coil domain cont... 50 6e-06
BC008285-1|AAH08285.1| 550|Homo sapiens coiled-coil domain cont... 50 6e-06
BC004307-1|AAH04307.1| 273|Homo sapiens CCDC102A protein protein. 50 6e-06
AL137068-7|CAD20123.1| 1007|Homo sapiens centrosomal protein 110... 50 6e-06
AL137068-5|CAI12358.1| 1773|Homo sapiens centrosomal protein 110... 50 6e-06
AL137068-2|CAM13285.1| 2325|Homo sapiens centrosomal protein 110... 50 6e-06
AK074079-1|BAB84905.1| 1793|Homo sapiens FLJ00150 protein protein. 50 6e-06
AF543495-1|AAN40505.1| 453|Homo sapiens melanoma-associated ant... 50 6e-06
AF513978-1|AAP43846.1| 2325|Homo sapiens CENTRIOLIN protein. 50 6e-06
AF432208-1|AAL99915.1| 187|Homo sapiens CLL-associated antigen ... 50 6e-06
AF083322-1|AAC32373.1| 994|Homo sapiens centriole associated pr... 50 6e-06
AB209109-1|BAD92346.1| 1096|Homo sapiens TATA element modulatory... 50 6e-06
AB053468-1|BAC54107.1| 992|Homo sapiens ELKS beta protein. 50 6e-06
AB029004-1|BAA83033.2| 1003|Homo sapiens KIAA1081 protein protein. 50 6e-06
AB015617-1|BAA88763.1| 948|Homo sapiens ELKS protein. 50 6e-06
Z99496-1|CAI21605.1| 805|Homo sapiens chromosome 6 open reading... 50 8e-06
S67247-1|AAB28952.1| 226|Homo sapiens smooth muscle myosin heav... 50 8e-06
M12128-1|AAA36775.1| 96|Homo sapiens protein ( Human cytoskele... 50 8e-06
BC118918-1|AAI18919.1| 1302|Homo sapiens cingulin-like 1 protein. 50 8e-06
BC112049-1|AAI12050.1| 1302|Homo sapiens cingulin-like 1 protein. 50 8e-06
BC093827-1|AAH93827.1| 1302|Homo sapiens cingulin-like 1 protein. 50 8e-06
BC089391-1|AAH89391.1| 466|Homo sapiens CCDC19 protein protein. 50 8e-06
BC086869-1|AAH86869.1| 954|Homo sapiens FLJ25770 protein protein. 50 8e-06
BC007808-1|AAH07808.1| 1006|Homo sapiens MYH7B protein protein. 50 8e-06
AY274808-1|AAP42073.1| 1302|Homo sapiens KIAA1749 protein protein. 50 8e-06
AL590560-10|CAH71107.1| 551|Homo sapiens coiled-coil domain con... 50 8e-06
AL589993-1|CAI16048.1| 805|Homo sapiens chromosome 6 open readi... 50 8e-06
AL589986-1|CAH70024.1| 1943|Homo sapiens trichohyalin protein. 50 8e-06
AL390069-1|CAI14134.1| 805|Homo sapiens chromosome 6 open readi... 50 8e-06
AF308284-1|AAG48252.1| 546|Homo sapiens serologically defined b... 50 8e-06
AB209693-1|BAD92930.1| 1310|Homo sapiens golgi autoantigen, golg... 50 8e-06
X03445-1|CAA27174.1| 572|Homo sapiens protein ( Human mRNA for ... 50 1e-05
X03444-1|CAA27173.1| 702|Homo sapiens protein ( Human mRNA for ... 50 1e-05
M13452-1|AAA36160.1| 515|Homo sapiens protein ( Human lamin A m... 50 1e-05
M13451-1|AAA36164.1| 572|Homo sapiens protein ( Human lamin C m... 50 1e-05
EF560736-1|ABQ59046.1| 916|Homo sapiens NEFM protein protein. 50 1e-05
BC126912-1|AAI26913.1| 1132|Homo sapiens CROCC protein protein. 50 1e-05
BC126911-1|AAI26912.1| 1132|Homo sapiens CROCC protein protein. 50 1e-05
BC096757-1|AAH96757.1| 916|Homo sapiens neurofilament, medium p... 50 1e-05
BC054492-1|AAH54492.1| 997|Homo sapiens RABGAP1 protein protein. 50 1e-05
BC033088-1|AAH33088.1| 465|Homo sapiens LMNA protein protein. 50 1e-05
BC014507-1|AAH14507.1| 664|Homo sapiens lamin A/C protein. 50 1e-05
BC003162-1|AAH03162.1| 572|Homo sapiens lamin A/C protein. 50 1e-05
BC000511-1|AAH00511.1| 572|Homo sapiens lamin A/C protein. 50 1e-05
AY847597-1|AAW32540.1| 664|Homo sapiens lamin A/C transcript va... 50 1e-05
AY847596-1|AAW32539.1| 480|Homo sapiens lamin A/C transcript va... 50 1e-05
AY528714-1|ABB04050.1| 487|Homo sapiens rhabdomyosarcoma antige... 50 1e-05
AY357727-1|AAR29466.1| 614|Homo sapiens progerin protein. 50 1e-05
AL365338-3|CAH70298.1| 997|Homo sapiens RAB GTPase activating p... 50 1e-05
AL135927-8|CAI15527.1| 491|Homo sapiens lamin A/C protein. 50 1e-05
AL135927-7|CAI15526.1| 513|Homo sapiens lamin A/C protein. 50 1e-05
AL135927-4|CAI15522.1| 664|Homo sapiens lamin A/C protein. 50 1e-05
AL135927-3|CAI15523.1| 614|Homo sapiens lamin A/C protein. 50 1e-05
AL135927-2|CAI15521.1| 572|Homo sapiens lamin A/C protein. 50 1e-05
AL135927-1|CAI15520.1| 465|Homo sapiens lamin A/C protein. 50 1e-05
AL050195-1|CAB43313.1| 246|Homo sapiens hypothetical protein pr... 50 1e-05
AL031283-6|CAI21428.1| 692|Homo sapiens forkhead-associated (FH... 50 1e-05
AK022532-1|BAB14081.1| 975|Homo sapiens protein ( Homo sapiens ... 50 1e-05
AJ011679-1|CAB40267.2| 997|Homo sapiens Rab6 GTPase activating ... 50 1e-05
AF181990-1|AAF00492.1| 260|Homo sapiens neurofilament-3 (150 kD... 50 1e-05
AF094758-1|AAD55817.1| 386|Homo sapiens nasopharyngeal epitheli... 50 1e-05
BC146835-1|AAI46836.1| 716|Homo sapiens Unknown (protein for MG... 49 1e-05
BC103765-1|AAI03766.1| 691|Homo sapiens NUMA1 protein protein. 49 1e-05
BC027493-1|AAH27493.1| 691|Homo sapiens NUMA1 protein protein. 49 1e-05
AY847595-1|AAW32538.1| 664|Homo sapiens lamin A/C transcript va... 49 1e-05
AK027863-1|BAB55415.1| 612|Homo sapiens protein ( Homo sapiens ... 49 1e-05
AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein. 49 1e-05
AB053469-1|BAC54108.1| 720|Homo sapiens ELKS gamma protein. 49 1e-05
AB046861-1|BAB13467.1| 718|Homo sapiens KIAA1641 protein protein. 49 1e-05
Y00067-1|CAA68276.1| 916|Homo sapiens NF-M protein. 49 2e-05
BC117182-1|AAI17183.1| 1654|Homo sapiens CEP152 protein protein. 49 2e-05
BC113524-1|AAI13525.1| 578|Homo sapiens IFT74 protein protein. 49 2e-05
BC092419-1|AAH92419.1| 701|Homo sapiens hypothetical LOC550631 ... 49 2e-05
BC023634-1|AAH23634.2| 383|Homo sapiens IFT74 protein protein. 49 2e-05
AY282407-1|AAP40331.1| 1116|Homo sapiens M-phase phosphoprotein ... 49 2e-05
AY040325-1|AAK77221.1| 600|Homo sapiens capillary morphogenesis... 49 2e-05
AL356133-4|CAH72643.1| 600|Homo sapiens intraflagellar transpor... 49 2e-05
AL157400-6|CAI16830.1| 1820|Homo sapiens M-phase phosphoprotein ... 49 2e-05
AL157400-5|CAI16831.1| 1780|Homo sapiens M-phase phosphoprotein ... 49 2e-05
AL157389-3|CAI12886.1| 1820|Homo sapiens M-phase phosphoprotein ... 49 2e-05
AL157389-2|CAI12887.1| 1780|Homo sapiens M-phase phosphoprotein ... 49 2e-05
AK023707-1|BAB14650.1| 435|Homo sapiens protein ( Homo sapiens ... 49 2e-05
AB067524-1|BAB67830.1| 704|Homo sapiens KIAA1937 protein protein. 49 2e-05
AB033337-1|BAB69456.1| 1820|Homo sapiens mitotic kinesin-related... 49 2e-05
AB020719-1|BAA74935.1| 1300|Homo sapiens KIAA0912 protein protein. 49 2e-05
BC004285-1|AAH04285.1| 498|Homo sapiens TCHP protein protein. 48 3e-05
AY007230-1|AAG12971.1| 498|Homo sapiens tumor suppressor protei... 48 3e-05
AL139421-1|CAI22508.1| 1454|Homo sapiens coiled-coil domain cont... 48 3e-05
AK092736-1|BAC03960.1| 498|Homo sapiens protein ( Homo sapiens ... 48 3e-05
AF295356-1|AAK71522.1| 527|Homo sapiens moesin/anaplastic lymph... 48 3e-05
Z97832-4|CAI20190.1| 631|Homo sapiens differentially expressed ... 48 3e-05
U93121-1|AAB88727.1| 753|Homo sapiens M-phase phosphoprotein-1 ... 48 3e-05
BX538186-1|CAD98058.1| 971|Homo sapiens hypothetical protein pr... 48 3e-05
BC131805-1|AAI31806.1| 913|Homo sapiens CCDC46 protein protein. 48 3e-05
BC057235-1|AAH57235.1| 613|Homo sapiens HMMR protein protein. 48 3e-05
AY739715-1|AAW65984.1| 617|Homo sapiens M-phase phosphoprotein ... 48 3e-05
AY642382-1|AAV34207.1| 1135|Homo sapiens GPBP-interacting protei... 48 3e-05
AY241694-1|AAO91767.1| 631|Homo sapiens IRF4-binding protein pr... 48 3e-05
AY014284-1|AAK27309.1| 699|Homo sapiens nucleoporin NYD-SP7 pro... 48 3e-05
AL162596-4|CAI19553.1| 585|Homo sapiens involucrin protein. 48 3e-05
AK024959-1|BAB15043.1| 696|Homo sapiens protein ( Homo sapiens ... 48 3e-05
AJ276095-1|CAC08450.1| 631|Homo sapiens Def-6 protein protein. 48 3e-05
AF514869-1|AAQ08179.1| 1133|Homo sapiens GPBP-interacting protei... 48 3e-05
AF514868-1|AAQ08178.1| 1133|Homo sapiens GPBP-interacting protei... 48 3e-05
AF514867-1|AAQ08177.1| 1135|Homo sapiens GPBP-interacting protei... 48 3e-05
AF458591-1|AAM49719.1| 590|Homo sapiens hypothetical protein pr... 48 3e-05
AF329092-1|AAN16206.1| 764|Homo sapiens GPBP-interacting protei... 48 3e-05
AF265230-1|AAK58539.1| 975|Homo sapiens RING finger protein 20 ... 48 3e-05
AF032862-1|AAC32548.1| 724|Homo sapiens intracellular hyaluroni... 48 3e-05
U29343-1|AAC52049.1| 725|Homo sapiens hyaluronan receptor protein. 48 4e-05
BC110585-1|AAI10586.1| 975|Homo sapiens ring finger protein 20 ... 48 4e-05
BC110584-1|AAI10585.1| 975|Homo sapiens ring finger protein 20 ... 48 4e-05
BC098576-1|AAH98576.1| 918|Homo sapiens inner centromere protei... 48 4e-05
BC041700-1|AAH41700.1| 862|Homo sapiens RABEP1 protein protein. 48 4e-05
BC032435-1|AAH32435.1| 716|Homo sapiens RABEP1 protein protein. 48 4e-05
AY714053-1|AAU04398.1| 918|Homo sapiens inner centromere protei... 48 4e-05
AY610514-1|AAT37906.1| 1302|Homo sapiens paracingulin protein. 48 4e-05
AL591377-3|CAH69963.1| 977|Homo sapiens ring finger protein 20 ... 48 4e-05
AL353621-9|CAI14618.1| 977|Homo sapiens ring finger protein 20 ... 48 4e-05
AK022300-1|BAB14005.1| 746|Homo sapiens protein ( Homo sapiens ... 48 4e-05
AJ131693-1|CAB40713.1| 3908|Homo sapiens AKAP450 protein protein. 48 4e-05
AJ010770-1|CAA09361.1| 3911|Homo sapiens Hyperion protein protein. 48 4e-05
AF091711-1|AAD39719.1| 1773|Homo sapiens splice variant AKAP350 ... 48 4e-05
AF083037-1|AAD22767.1| 3595|Homo sapiens A-kinase anchoring prot... 48 4e-05
AC004013-1|AAB96867.2| 2058|Homo sapiens unknown protein. 48 4e-05
AB019691-1|BAA78718.1| 3899|Homo sapiens Centrosome- and Golgi-l... 48 4e-05
AB018346-1|BAA34523.1| 1708|Homo sapiens KIAA0803 protein protein. 48 4e-05
Z98882-1|CAI95591.1| 756|Homo sapiens RAB11 family interacting ... 47 6e-05
Z26653-1|CAA81394.1| 3110|Homo sapiens laminin M chain (merosin)... 47 6e-05
U66796-1|AAB18388.1| 3110|Homo sapiens laminin alpha 2 chain pro... 47 6e-05
BC130453-1|AAI30454.1| 1726|Homo sapiens ANKRD26 protein protein. 47 6e-05
BC108904-1|AAI08905.1| 725|Homo sapiens hyaluronan-mediated mot... 47 6e-05
BC070281-1|AAH70281.1| 552|Homo sapiens HMMR protein protein. 47 6e-05
BC060769-1|AAH60769.2| 1107|Homo sapiens chromosome 6 open readi... 47 6e-05
BC051360-1|AAH51360.1| 756|Homo sapiens RAB11 family interactin... 47 6e-05
BC007877-1|AAH07877.2| 256|Homo sapiens MYH14 protein protein. 47 6e-05
AY528715-1|AAT44400.1| 1016|Homo sapiens antigen MU-RMS-40.16A p... 47 6e-05
AL669984-2|CAI16682.1| 3122|Homo sapiens laminin, alpha 2 (meros... 47 6e-05
AL590613-1|CAH70771.1| 3122|Homo sapiens laminin, alpha 2 (meros... 47 6e-05
AL583853-1|CAH70492.1| 3122|Homo sapiens laminin, alpha 2 (meros... 47 6e-05
AL513527-1|CAI15185.1| 3122|Homo sapiens laminin, alpha 2 (meros... 47 6e-05
AL445439-1|CAH72952.1| 3122|Homo sapiens laminin, alpha 2 (meros... 47 6e-05
AL365275-1|CAI40383.1| 1140|Homo sapiens chromosome 6 open readi... 47 6e-05
AL356124-1|CAI22470.1| 3122|Homo sapiens laminin, alpha 2 (meros... 47 6e-05
AL162272-4|CAC19649.1| 1710|Homo sapiens novel protein protein. 47 6e-05
AL137009-1|CAI20344.1| 1140|Homo sapiens chromosome 6 open readi... 47 6e-05
AL132874-2|CAI42604.1| 1140|Homo sapiens chromosome 6 open readi... 47 6e-05
>M19713-1|AAA61225.1| 284|Homo sapiens TPM1 protein.
Length = 284
Score = 214 bits (523), Expect = 2e-55
Identities = 108/217 (49%), Positives = 158/217 (72%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
MDAIKKKMQ +KL+K+NA+D+A+ E + A R++++ +E+ LQKKL E++L
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
L+ A + LE EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
DE+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+R + + K +ELEEELK V N+LKSLE EK +Q+
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQK 217
Score = 70.5 bits (165), Expect = 6e-12
Identities = 46/209 (22%), Positives = 107/209 (51%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 142
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ ++ K E ++
Sbjct: 143 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGKCAELEE 195
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
K LE +A++ ++ D+ ++K ++A+ +++ R + +E ++
Sbjct: 196 ELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 255
Query: 601 AEDRVKSGDAKISELEEELKVVGNSLKSL 687
ED + + K + EEL N + S+
Sbjct: 256 LEDELYAQKLKYKAISEELDHALNDMTSI 284
Score = 50.4 bits (115), Expect = 6e-06
Identities = 33/140 (23%), Positives = 73/140 (52%), Gaps = 7/140 (5%)
Frame = +1
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
A+ +K+Q ++ D E + +R+ A+ A+ + + L+ + + E+ +D+ +
Sbjct: 3 AIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSE 62
Query: 505 QLKEARL---LAE----DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKV 663
LK+A+ LAE DA+ ++R++ VE+EL+ A++R+ + K+ E E+
Sbjct: 63 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
Query: 664 VGNSLKSLEVSEEKANQRVE 723
+K +E +K +++E
Sbjct: 123 SERGMKVIESRAQKDEEKME 142
>AY640415-1|AAT68295.1| 284|Homo sapiens tropomyosin alpha striated
muscle isoform protein.
Length = 284
Score = 214 bits (522), Expect = 3e-55
Identities = 108/217 (49%), Positives = 157/217 (72%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
MDAIKKKMQ +KL+K+NA+D+A+ E + A R++++ +E+ LQKKL E++L
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
L+ A + LE EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
DE+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+R + + K +ELEEELK V N LKSLE EK +Q+
Sbjct: 181 ERAELSEGKCAELEEELKTVTNDLKSLEAQAEKYSQK 217
Score = 70.1 bits (164), Expect = 7e-12
Identities = 46/209 (22%), Positives = 107/209 (51%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 142
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ ++ K E ++
Sbjct: 143 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGKCAELEE 195
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
K LE +A++ ++ D+ ++K ++A+ +++ R + +E ++
Sbjct: 196 ELKTVTNDLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 255
Query: 601 AEDRVKSGDAKISELEEELKVVGNSLKSL 687
ED + + K + EEL N + S+
Sbjct: 256 LEDELYAQKLKYKAISEELDHALNDMTSI 284
Score = 50.4 bits (115), Expect = 6e-06
Identities = 33/140 (23%), Positives = 73/140 (52%), Gaps = 7/140 (5%)
Frame = +1
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
A+ +K+Q ++ D E + +R+ A+ A+ + + L+ + + E+ +D+ +
Sbjct: 3 AIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSE 62
Query: 505 QLKEARL---LAE----DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKV 663
LK+A+ LAE DA+ ++R++ VE+EL+ A++R+ + K+ E E+
Sbjct: 63 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
Query: 664 VGNSLKSLEVSEEKANQRVE 723
+K +E +K +++E
Sbjct: 123 SERGMKVIESRAQKDEEKME 142
>X06825-1|CAA29971.1| 284|Homo sapiens protein ( Human mRNA for
skeletal beta-tropomyosin. ).
Length = 284
Score = 211 bits (515), Expect = 2e-54
Identities = 103/213 (48%), Positives = 156/213 (73%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+R + ++K +LEEELK+V N+LKSLE +K
Sbjct: 181 ERAEVAESKCGDLEEELKIVTNNLKSLEAQADK 213
Score = 70.9 bits (166), Expect = 4e-12
Identities = 49/209 (23%), Positives = 106/209 (50%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKME 142
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
L + +L++A E+ +++ EVA RK+ +E +LE+SEER+ A+ K + ++
Sbjct: 143 LQEMQLKEAKHIAEDSDRKYE----EVA---RKLVILEGELERSEERAEVAESKCGDLEE 195
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
K LE +A + + D+ ++K ++A+ +++ R +A +E ++
Sbjct: 196 ELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDD 255
Query: 601 AEDRVKSGDAKISELEEELKVVGNSLKSL 687
ED V + K + EEL N + SL
Sbjct: 256 LEDEVYAQKMKYKAISEELDNALNDITSL 284
Score = 50.4 bits (115), Expect = 6e-06
Identities = 31/135 (22%), Positives = 73/135 (54%), Gaps = 7/135 (5%)
Frame = +1
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
A+ +K+Q ++ D E + +R+ A+ +A+ + + L+ + + E+ +++ +
Sbjct: 3 AIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSE 62
Query: 505 QLKEARLLAEDADGKSDE-------VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKV 663
+KEA+ E A+ K+ + ++R++ VE+EL+ A++R+ + + +LEE K
Sbjct: 63 SVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATA---LQKLEEAEKA 119
Query: 664 VGNSLKSLEVSEEKA 708
S + ++V E +A
Sbjct: 120 ADESERGMKVIENRA 134
>AL133410-4|CAI10977.1| 284|Homo sapiens tropomyosin 2 (beta)
protein.
Length = 284
Score = 211 bits (515), Expect = 2e-54
Identities = 103/213 (48%), Positives = 156/213 (73%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+R + ++K +LEEELK+V N+LKSLE +K
Sbjct: 181 ERAEVAESKCGDLEEELKIVTNNLKSLEAQADK 213
Score = 70.9 bits (166), Expect = 4e-12
Identities = 49/209 (23%), Positives = 106/209 (50%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKME 142
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
L + +L++A E+ +++ EVA RK+ +E +LE+SEER+ A+ K + ++
Sbjct: 143 LQEMQLKEAKHIAEDSDRKYE----EVA---RKLVILEGELERSEERAEVAESKCGDLEE 195
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
K LE +A + + D+ ++K ++A+ +++ R +A +E ++
Sbjct: 196 ELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDD 255
Query: 601 AEDRVKSGDAKISELEEELKVVGNSLKSL 687
ED V + K + EEL N + SL
Sbjct: 256 LEDEVYAQKMKYKAISEELDNALNDITSL 284
Score = 50.4 bits (115), Expect = 6e-06
Identities = 31/135 (22%), Positives = 73/135 (54%), Gaps = 7/135 (5%)
Frame = +1
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
A+ +K+Q ++ D E + +R+ A+ +A+ + + L+ + + E+ +++ +
Sbjct: 3 AIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSE 62
Query: 505 QLKEARLLAEDADGKSDE-------VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKV 663
+KEA+ E A+ K+ + ++R++ VE+EL+ A++R+ + + +LEE K
Sbjct: 63 SVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATA---LQKLEEAEKA 119
Query: 664 VGNSLKSLEVSEEKA 708
S + ++V E +A
Sbjct: 120 ADESERGMKVIENRA 134
>AL133410-3|CAI10976.1| 322|Homo sapiens tropomyosin 2 (beta)
protein.
Length = 322
Score = 211 bits (515), Expect = 2e-54
Identities = 103/213 (48%), Positives = 156/213 (73%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+R + ++K +LEEELK+V N+LKSLE +K
Sbjct: 181 ERAEVAESKCGDLEEELKIVTNNLKSLEAQADK 213
Score = 50.4 bits (115), Expect = 6e-06
Identities = 31/135 (22%), Positives = 73/135 (54%), Gaps = 7/135 (5%)
Frame = +1
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
A+ +K+Q ++ D E + +R+ A+ +A+ + + L+ + + E+ +++ +
Sbjct: 3 AIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSE 62
Query: 505 QLKEARLLAEDADGKSDE-------VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKV 663
+KEA+ E A+ K+ + ++R++ VE+EL+ A++R+ + + +LEE K
Sbjct: 63 SVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATA---LQKLEEAEKA 119
Query: 664 VGNSLKSLEVSEEKA 708
S + ++V E +A
Sbjct: 120 ADESERGMKVIENRA 134
>AL133410-1|CAI10975.1| 284|Homo sapiens tropomyosin 2 (beta)
protein.
Length = 284
Score = 211 bits (515), Expect = 2e-54
Identities = 103/213 (48%), Positives = 156/213 (73%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+R + ++K +LEEELK+V N+LKSLE +K
Sbjct: 181 ERAEVAESKCGDLEEELKIVTNNLKSLEAQADK 213
Score = 62.9 bits (146), Expect = 1e-09
Identities = 43/199 (21%), Positives = 102/199 (51%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKME 142
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
L + +L++A E+ +++ EVA RK+ +E +LE+SEER+ A+ K + ++
Sbjct: 143 LQEMQLKEAKHIAEDSDRKYE----EVA---RKLVILEGELERSEERAEVAESKCGDLEE 195
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
K LE +A + + D+ ++K ++A+ +++ R +A +E ++
Sbjct: 196 ELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDD 255
Query: 601 AEDRVKSGDAKISELEEEL 657
E+ + S + E+ + L
Sbjct: 256 LEETLASAKEENVEIHQTL 274
Score = 50.4 bits (115), Expect = 6e-06
Identities = 31/135 (22%), Positives = 73/135 (54%), Gaps = 7/135 (5%)
Frame = +1
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
A+ +K+Q ++ D E + +R+ A+ +A+ + + L+ + + E+ +++ +
Sbjct: 3 AIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSE 62
Query: 505 QLKEARLLAEDADGKSDE-------VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKV 663
+KEA+ E A+ K+ + ++R++ VE+EL+ A++R+ + + +LEE K
Sbjct: 63 SVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATA---LQKLEEAEKA 119
Query: 664 VGNSLKSLEVSEEKA 708
S + ++V E +A
Sbjct: 120 ADESERGMKVIENRA 134
Score = 41.9 bits (94), Expect = 0.002
Identities = 39/161 (24%), Positives = 77/161 (47%), Gaps = 10/161 (6%)
Frame = +1
Query: 73 AIKKKMQAMKLEKDNAM---DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
A + + MK+ ++ AM +K + E Q ++A AE + + E+ +KL +E +L
Sbjct: 119 AADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELER 178
Query: 244 NKNKLEQANK---DLEEKEKQLT----ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 402
++ + E A DLEE+ K +T + EA+ + K + EE+++ EE+ A+ +
Sbjct: 179 SEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETR 238
Query: 403 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 525
A++S + + LE +E ++ L + L
Sbjct: 239 AEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLL 279
>X04201-1|CAA27798.1| 285|Homo sapiens protein ( Human skeletal
muscle 1.3 kb mRNA for tropomyosin. ).
Length = 285
Score = 210 bits (512), Expect = 5e-54
Identities = 105/217 (48%), Positives = 157/217 (72%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
M+AIKKKMQ +KL+K+NA+D+A+ E + + A R++++ +E+ +QKKL E++L
Sbjct: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
L+ A + LE EK+ EAEVA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E +LE E
Sbjct: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+R + ++K SELEEELK V N+LKSLE EK +Q+
Sbjct: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQK 218
Score = 74.5 bits (175), Expect = 3e-13
Identities = 50/209 (23%), Positives = 108/209 (51%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 84 AEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKME 143
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ K E ++
Sbjct: 144 LQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESKCSELEE 196
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
K LE +A++ ++ D+ ++K ++A+ +++ R +A +E ++
Sbjct: 197 ELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDD 256
Query: 601 AEDRVKSGDAKISELEEELKVVGNSLKSL 687
ED + + K + EEL N + S+
Sbjct: 257 LEDELYAQKLKYKAISEELDHALNDMTSI 285
Score = 44.4 bits (100), Expect = 4e-04
Identities = 42/180 (23%), Positives = 75/180 (41%), Gaps = 21/180 (11%)
Frame = +1
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI--------------EEDLEKSEERS 384
K K++ D E + EAE + +Q+ E++L+K E
Sbjct: 6 KKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEAL 65
Query: 385 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 564
AQ+KL A++ A + L R Q EE +D+ +L A E+A+ +DE
Sbjct: 66 KDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 125
Query: 565 RKLAFV-------EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
R + + E+++E+ E ++K E + + + V L +E E+ +R E
Sbjct: 126 RGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAE 185
>BC008425-1|AAH08425.1| 285|Homo sapiens tropomyosin 3 protein.
Length = 285
Score = 210 bits (512), Expect = 5e-54
Identities = 105/217 (48%), Positives = 157/217 (72%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
M+AIKKKMQ +KL+K+NA+D+A+ E + + A R++++ +E+ +QKKL E++L
Sbjct: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
L+ A + LE EK+ EAEVA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E +LE E
Sbjct: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+R + ++K SELEEELK V N+LKSLE EK +Q+
Sbjct: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQK 218
Score = 74.5 bits (175), Expect = 3e-13
Identities = 50/209 (23%), Positives = 108/209 (51%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 84 AEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKME 143
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ K E ++
Sbjct: 144 LQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESKCSELEE 196
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
K LE +A++ ++ D+ ++K ++A+ +++ R +A +E ++
Sbjct: 197 ELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDD 256
Query: 601 AEDRVKSGDAKISELEEELKVVGNSLKSL 687
ED + + K + EEL N + S+
Sbjct: 257 LEDELYAQKLKYKAISEELDHALNDMTSI 285
Score = 44.4 bits (100), Expect = 4e-04
Identities = 42/180 (23%), Positives = 75/180 (41%), Gaps = 21/180 (11%)
Frame = +1
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI--------------EEDLEKSEERS 384
K K++ D E + EAE + +Q+ E++L+K E
Sbjct: 6 KKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEAL 65
Query: 385 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 564
AQ+KL A++ A + L R Q EE +D+ +L A E+A+ +DE
Sbjct: 66 KDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 125
Query: 565 RKLAFV-------EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
R + + E+++E+ E ++K E + + + V L +E E+ +R E
Sbjct: 126 RGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAE 185
>BC008407-1|AAH08407.1| 285|Homo sapiens tropomyosin 3 protein.
Length = 285
Score = 210 bits (512), Expect = 5e-54
Identities = 105/217 (48%), Positives = 157/217 (72%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
M+AIKKKMQ +KL+K+NA+D+A+ E + + A R++++ +E+ +QKKL E++L
Sbjct: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
L+ A + LE EK+ EAEVA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E +LE E
Sbjct: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+R + ++K SELEEELK V N+LKSLE EK +Q+
Sbjct: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQK 218
Score = 74.5 bits (175), Expect = 3e-13
Identities = 50/209 (23%), Positives = 108/209 (51%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 84 AEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKME 143
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ K E ++
Sbjct: 144 LQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESKCSELEE 196
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
K LE +A++ ++ D+ ++K ++A+ +++ R +A +E ++
Sbjct: 197 ELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDD 256
Query: 601 AEDRVKSGDAKISELEEELKVVGNSLKSL 687
ED + + K + EEL N + S+
Sbjct: 257 LEDELYAQKLKYKAISEELDHALNDMTSI 285
Score = 44.4 bits (100), Expect = 4e-04
Identities = 42/180 (23%), Positives = 75/180 (41%), Gaps = 21/180 (11%)
Frame = +1
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI--------------EEDLEKSEERS 384
K K++ D E + EAE + +Q+ E++L+K E
Sbjct: 6 KKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEAL 65
Query: 385 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 564
AQ+KL A++ A + L R Q EE +D+ +L A E+A+ +DE
Sbjct: 66 KDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 125
Query: 565 RKLAFV-------EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
R + + E+++E+ E ++K E + + + V L +E E+ +R E
Sbjct: 126 RGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAE 185
>AL590431-12|CAH71269.1| 284|Homo sapiens tropomyosin 3 protein.
Length = 284
Score = 210 bits (512), Expect = 5e-54
Identities = 105/217 (48%), Positives = 157/217 (72%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
M+AIKKKMQ +KL+K+NA+D+A+ E + + A R++++ +E+ +QKKL E++L
Sbjct: 1 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 60
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
L+ A + LE EK+ EAEVA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E +LE E
Sbjct: 121 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 180
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+R + ++K SELEEELK V N+LKSLE EK +Q+
Sbjct: 181 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQK 217
Score = 74.5 bits (175), Expect = 3e-13
Identities = 50/209 (23%), Positives = 108/209 (51%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 83 AEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKME 142
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ K E ++
Sbjct: 143 LQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESKCSELEE 195
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
K LE +A++ ++ D+ ++K ++A+ +++ R +A +E ++
Sbjct: 196 ELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDD 255
Query: 601 AEDRVKSGDAKISELEEELKVVGNSLKSL 687
ED + + K + EEL N + S+
Sbjct: 256 LEDELYAQKLKYKAISEELDHALNDMTSI 284
Score = 44.4 bits (100), Expect = 4e-04
Identities = 42/180 (23%), Positives = 75/180 (41%), Gaps = 21/180 (11%)
Frame = +1
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI--------------EEDLEKSEERS 384
K K++ D E + EAE + +Q+ E++L+K E
Sbjct: 5 KKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEAL 64
Query: 385 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 564
AQ+KL A++ A + L R Q EE +D+ +L A E+A+ +DE
Sbjct: 65 KDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
Query: 565 RKLAFV-------EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
R + + E+++E+ E ++K E + + + V L +E E+ +R E
Sbjct: 125 RGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAE 184
>AK023385-1|BAB14554.1| 284|Homo sapiens protein ( Homo sapiens
cDNA FLJ13323 fis, clone OVARC1001731, highly similar to
TROPOMYOSIN ALPHA CHAIN, FIBROBLAST ISOFORM F2. ).
Length = 284
Score = 207 bits (505), Expect = 4e-53
Identities = 105/217 (48%), Positives = 155/217 (71%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
M+AIKKKMQ +KL+K+NA+D+A+ E + A + ++V EE+ LQKKL E++L
Sbjct: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
L+ A + LE EK+ + E +VAALNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E ELE AE
Sbjct: 121 DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE 180
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+R + + K +LEEELK V N+LKSLE + EK +++
Sbjct: 181 ERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEK 217
>M19267-1|AAA36771.1| 284|Homo sapiens protein ( Human tropomyosin
mRNA, complete cds. ).
Length = 284
Score = 205 bits (501), Expect = 1e-52
Identities = 100/217 (46%), Positives = 159/217 (73%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
MDAIKKKMQ +KL+K+NA+D+A+ E + A R++++ +E+ LQKKL E++L
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
L+ A + LE EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
DE+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+R + + ++ +LEE+L+++ +LK+L +E+K +Q+
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQK 217
Score = 60.5 bits (140), Expect = 6e-09
Identities = 46/190 (24%), Positives = 103/190 (54%), Gaps = 7/190 (3%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 142
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEA 414
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ Q + LE
Sbjct: 143 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGQVRQLEE 195
Query: 415 Q-QSADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAF 579
Q + D+ + E++ Q E+R ++ L+++LKEA AE A+ ++ + +
Sbjct: 196 QLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 255
Query: 580 VEDELEVAED 609
+E+++ A++
Sbjct: 256 LEEKVAHAKE 265
Score = 50.4 bits (115), Expect = 6e-06
Identities = 33/140 (23%), Positives = 73/140 (52%), Gaps = 7/140 (5%)
Frame = +1
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
A+ +K+Q ++ D E + +R+ A+ A+ + + L+ + + E+ +D+ +
Sbjct: 3 AIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSE 62
Query: 505 QLKEARL---LAE----DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKV 663
LK+A+ LAE DA+ ++R++ VE+EL+ A++R+ + K+ E E+
Sbjct: 63 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
Query: 664 VGNSLKSLEVSEEKANQRVE 723
+K +E +K +++E
Sbjct: 123 SERGMKVIESRAQKDEEKME 142
Score = 32.3 bits (70), Expect = 1.8
Identities = 21/104 (20%), Positives = 51/104 (49%), Gaps = 7/104 (6%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQ-------KKLAQVE 228
+ + +K+ ++ + + A ++A+ E Q R + +++ ++ L +K + E
Sbjct: 163 EEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYE 222
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEED 360
E++ + +KL++A E E+ +T E + L KV +E+
Sbjct: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
>BC007433-1|AAH07433.1| 284|Homo sapiens tropomyosin 1 (alpha)
protein.
Length = 284
Score = 205 bits (501), Expect = 1e-52
Identities = 100/217 (46%), Positives = 159/217 (73%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
MDAIKKKMQ +KL+K+NA+D+A+ E + A R++++ +E+ LQKKL E++L
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
L+ A + LE EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
DE+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+R + + ++ +LEE+L+++ +LK+L +E+K +Q+
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQK 217
Score = 64.1 bits (149), Expect = 5e-10
Identities = 49/194 (25%), Positives = 104/194 (53%), Gaps = 7/194 (3%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 142
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEA 414
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ Q + LE
Sbjct: 143 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGQVRQLEE 195
Query: 415 Q-QSADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAF 579
Q + D+ + E++ Q E+R ++ L+++LKEA AE A+ ++ + +
Sbjct: 196 QLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 255
Query: 580 VEDELEVAEDRVKS 621
+EDEL + + K+
Sbjct: 256 LEDELYAQKLKYKA 269
Score = 50.4 bits (115), Expect = 6e-06
Identities = 33/140 (23%), Positives = 73/140 (52%), Gaps = 7/140 (5%)
Frame = +1
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
A+ +K+Q ++ D E + +R+ A+ A+ + + L+ + + E+ +D+ +
Sbjct: 3 AIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSE 62
Query: 505 QLKEARL---LAE----DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKV 663
LK+A+ LAE DA+ ++R++ VE+EL+ A++R+ + K+ E E+
Sbjct: 63 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
Query: 664 VGNSLKSLEVSEEKANQRVE 723
+K +E +K +++E
Sbjct: 123 SERGMKVIESRAQKDEEKME 142
>M75165-1|AAB59509.1| 284|Homo sapiens tropomyosin protein.
Length = 284
Score = 204 bits (499), Expect = 2e-52
Identities = 100/213 (46%), Positives = 155/213 (72%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+R + +++ +LEEEL+ + +LKSL SEE+
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEE 213
Score = 50.4 bits (115), Expect = 6e-06
Identities = 31/135 (22%), Positives = 73/135 (54%), Gaps = 7/135 (5%)
Frame = +1
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
A+ +K+Q ++ D E + +R+ A+ +A+ + + L+ + + E+ +++ +
Sbjct: 3 AIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSE 62
Query: 505 QLKEARLLAEDADGKSDE-------VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKV 663
+KEA+ E A+ K+ + ++R++ VE+EL+ A++R+ + + +LEE K
Sbjct: 63 SVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATA---LQKLEEAEKA 119
Query: 664 VGNSLKSLEVSEEKA 708
S + ++V E +A
Sbjct: 120 ADESERGMKVIENRA 134
Score = 37.1 bits (82), Expect = 0.064
Identities = 34/161 (21%), Positives = 74/161 (45%), Gaps = 10/161 (6%)
Frame = +1
Query: 73 AIKKKMQAMKLEKDNAM---DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
A + + MK+ ++ AM +K + E Q ++A AE + + E+ +KL +E +L
Sbjct: 119 AADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELER 178
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAAL-------NRKVQQIEEDLEKSEERSGTAQQK 402
++ + E A + E++L + + +L + K + EE+++ EE+ A+ +
Sbjct: 179 SEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETR 238
Query: 403 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 525
A++S + + LE +E ++ L + L
Sbjct: 239 AEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLL 279
>M74817-1|AAA61230.1| 284|Homo sapiens tropomyosin-1 protein.
Length = 284
Score = 204 bits (499), Expect = 2e-52
Identities = 100/213 (46%), Positives = 155/213 (72%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+R + +++ +LEEEL+ + +LKSL SEE+
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEE 213
Score = 50.4 bits (115), Expect = 6e-06
Identities = 31/135 (22%), Positives = 73/135 (54%), Gaps = 7/135 (5%)
Frame = +1
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
A+ +K+Q ++ D E + +R+ A+ +A+ + + L+ + + E+ +++ +
Sbjct: 3 AIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSE 62
Query: 505 QLKEARLLAEDADGKSDE-------VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKV 663
+KEA+ E A+ K+ + ++R++ VE+EL+ A++R+ + + +LEE K
Sbjct: 63 SVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATA---LQKLEEAEKA 119
Query: 664 VGNSLKSLEVSEEKA 708
S + ++V E +A
Sbjct: 120 ADESERGMKVIENRA 134
Score = 37.1 bits (82), Expect = 0.064
Identities = 34/161 (21%), Positives = 74/161 (45%), Gaps = 10/161 (6%)
Frame = +1
Query: 73 AIKKKMQAMKLEKDNAM---DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
A + + MK+ ++ AM +K + E Q ++A AE + + E+ +KL +E +L
Sbjct: 119 AADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELER 178
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAAL-------NRKVQQIEEDLEKSEERSGTAQQK 402
++ + E A + E++L + + +L + K + EE+++ EE+ A+ +
Sbjct: 179 SEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETR 238
Query: 403 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 525
A++S + + LE +E ++ L + L
Sbjct: 239 AEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLL 279
>M12125-1|AAA36773.1| 284|Homo sapiens protein ( Human fibroblast
muscle-type tropomyosin mRNA, complete cds. ).
Length = 284
Score = 204 bits (499), Expect = 2e-52
Identities = 100/213 (46%), Positives = 155/213 (72%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+R + +++ +LEEEL+ + +LKSL SEE+
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEE 213
Score = 50.4 bits (115), Expect = 6e-06
Identities = 31/135 (22%), Positives = 73/135 (54%), Gaps = 7/135 (5%)
Frame = +1
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
A+ +K+Q ++ D E + +R+ A+ +A+ + + L+ + + E+ +++ +
Sbjct: 3 AIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSE 62
Query: 505 QLKEARLLAEDADGKSDE-------VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKV 663
+KEA+ E A+ K+ + ++R++ VE+EL+ A++R+ + + +LEE K
Sbjct: 63 SVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATA---LQKLEEAEKA 119
Query: 664 VGNSLKSLEVSEEKA 708
S + ++V E +A
Sbjct: 120 ADESERGMKVIENRA 134
Score = 37.1 bits (82), Expect = 0.064
Identities = 34/161 (21%), Positives = 74/161 (45%), Gaps = 10/161 (6%)
Frame = +1
Query: 73 AIKKKMQAMKLEKDNAM---DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
A + + MK+ ++ AM +K + E Q ++A AE + + E+ +KL +E +L
Sbjct: 119 AADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELER 178
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAAL-------NRKVQQIEEDLEKSEERSGTAQQK 402
++ + E A + E++L + + +L + K + EE+++ EE+ A+ +
Sbjct: 179 SEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETR 238
Query: 403 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 525
A++S + + LE +E ++ L + L
Sbjct: 239 AEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLL 279
>BC011776-1|AAH11776.1| 284|Homo sapiens tropomyosin 2 (beta)
protein.
Length = 284
Score = 204 bits (499), Expect = 2e-52
Identities = 100/213 (46%), Positives = 155/213 (72%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+R + +++ +LEEEL+ + +LKSL SEE+
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEE 213
Score = 50.4 bits (115), Expect = 6e-06
Identities = 31/135 (22%), Positives = 73/135 (54%), Gaps = 7/135 (5%)
Frame = +1
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
A+ +K+Q ++ D E + +R+ A+ +A+ + + L+ + + E+ +++ +
Sbjct: 3 AIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSE 62
Query: 505 QLKEARLLAEDADGKSDE-------VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKV 663
+KEA+ E A+ K+ + ++R++ VE+EL+ A++R+ + + +LEE K
Sbjct: 63 SVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATA---LQKLEEAEKA 119
Query: 664 VGNSLKSLEVSEEKA 708
S + ++V E +A
Sbjct: 120 ADESERGMKVIENRA 134
Score = 37.1 bits (82), Expect = 0.064
Identities = 34/161 (21%), Positives = 74/161 (45%), Gaps = 10/161 (6%)
Frame = +1
Query: 73 AIKKKMQAMKLEKDNAM---DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
A + + MK+ ++ AM +K + E Q ++A AE + + E+ +KL +E +L
Sbjct: 119 AADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELER 178
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAAL-------NRKVQQIEEDLEKSEERSGTAQQK 402
++ + E A + E++L + + +L + K + EE+++ EE+ A+ +
Sbjct: 179 SEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETR 238
Query: 403 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 525
A++S + + LE +E ++ L + L
Sbjct: 239 AEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLL 279
>AL133410-2|CAI10974.1| 284|Homo sapiens tropomyosin 2 (beta)
protein.
Length = 284
Score = 204 bits (499), Expect = 2e-52
Identities = 100/213 (46%), Positives = 155/213 (72%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+R + +++ +LEEEL+ + +LKSL SEE+
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEE 213
Score = 50.4 bits (115), Expect = 6e-06
Identities = 31/135 (22%), Positives = 73/135 (54%), Gaps = 7/135 (5%)
Frame = +1
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
A+ +K+Q ++ D E + +R+ A+ +A+ + + L+ + + E+ +++ +
Sbjct: 3 AIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSE 62
Query: 505 QLKEARLLAEDADGKSDE-------VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKV 663
+KEA+ E A+ K+ + ++R++ VE+EL+ A++R+ + + +LEE K
Sbjct: 63 SVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATA---LQKLEEAEKA 119
Query: 664 VGNSLKSLEVSEEKA 708
S + ++V E +A
Sbjct: 120 ADESERGMKVIENRA 134
Score = 37.1 bits (82), Expect = 0.064
Identities = 34/161 (21%), Positives = 74/161 (45%), Gaps = 10/161 (6%)
Frame = +1
Query: 73 AIKKKMQAMKLEKDNAM---DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
A + + MK+ ++ AM +K + E Q ++A AE + + E+ +KL +E +L
Sbjct: 119 AADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELER 178
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAAL-------NRKVQQIEEDLEKSEERSGTAQQK 402
++ + E A + E++L + + +L + K + EE+++ EE+ A+ +
Sbjct: 179 SEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETR 238
Query: 403 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 525
A++S + + LE +E ++ L + L
Sbjct: 239 AEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLL 279
>AF209746-1|AAF17621.1| 257|Homo sapiens beta tropomyosin protein.
Length = 257
Score = 204 bits (499), Expect = 2e-52
Identities = 100/213 (46%), Positives = 155/213 (72%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+R + +++ +LEEEL+ + +LKSL SEE+
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEE 213
Score = 50.4 bits (115), Expect = 6e-06
Identities = 31/135 (22%), Positives = 73/135 (54%), Gaps = 7/135 (5%)
Frame = +1
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
A+ +K+Q ++ D E + +R+ A+ +A+ + + L+ + + E+ +++ +
Sbjct: 3 AIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSE 62
Query: 505 QLKEARLLAEDADGKSDE-------VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKV 663
+KEA+ E A+ K+ + ++R++ VE+EL+ A++R+ + + +LEE K
Sbjct: 63 SVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATA---LQKLEEAEKA 119
Query: 664 VGNSLKSLEVSEEKA 708
S + ++V E +A
Sbjct: 120 ADESERGMKVIENRA 134
>AK223258-1|BAD96978.1| 284|Homo sapiens tropomyosin 2 (beta)
isoform 2 variant protein.
Length = 284
Score = 202 bits (494), Expect = 8e-52
Identities = 99/213 (46%), Positives = 155/213 (72%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+++A + LE+ EK+ T EA+VA+L+R++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLSRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+R + +++ +LEEEL+ + +LKSL SEE+
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEE 213
Score = 51.6 bits (118), Expect = 3e-06
Identities = 32/135 (23%), Positives = 73/135 (54%), Gaps = 7/135 (5%)
Frame = +1
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
A+ +K+Q ++ D E + +R+ A+ +A+ + + L+ + + E+ +++ +
Sbjct: 3 AIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSE 62
Query: 505 QLKEARLLAEDADGKSDE-------VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKV 663
+KEA+ E A+ K+ + +SR++ VE+EL+ A++R+ + + +LEE K
Sbjct: 63 SVKEAQEKLEQAEKKATDAEADVASLSRRIQLVEEELDRAQERLATA---LQKLEEAEKA 119
Query: 664 VGNSLKSLEVSEEKA 708
S + ++V E +A
Sbjct: 120 ADESERGMKVIENRA 134
Score = 37.1 bits (82), Expect = 0.064
Identities = 34/161 (21%), Positives = 74/161 (45%), Gaps = 10/161 (6%)
Frame = +1
Query: 73 AIKKKMQAMKLEKDNAM---DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
A + + MK+ ++ AM +K + E Q ++A AE + + E+ +KL +E +L
Sbjct: 119 AADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELER 178
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAAL-------NRKVQQIEEDLEKSEERSGTAQQK 402
++ + E A + E++L + + +L + K + EE+++ EE+ A+ +
Sbjct: 179 SEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETR 238
Query: 403 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 525
A++S + + LE +E ++ L + L
Sbjct: 239 AEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLL 279
>AY640414-1|AAT68294.1| 284|Homo sapiens sarcomeric tropomyosin
kappa protein.
Length = 284
Score = 198 bits (483), Expect = 2e-50
Identities = 101/217 (46%), Positives = 151/217 (69%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
MDAIKKKMQ +KL+K+NA+D+A+ E + A R++++ E++ +K L E++
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+L +A L E+ EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
DE+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+R + + K +ELEEELK V N LKSLE EK +Q+
Sbjct: 181 ERAELSEGKCAELEEELKTVTNDLKSLEAQAEKYSQK 217
Score = 70.1 bits (164), Expect = 7e-12
Identities = 46/209 (22%), Positives = 107/209 (51%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 142
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ ++ K E ++
Sbjct: 143 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGKCAELEE 195
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
K LE +A++ ++ D+ ++K ++A+ +++ R + +E ++
Sbjct: 196 ELKTVTNDLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 255
Query: 601 AEDRVKSGDAKISELEEELKVVGNSLKSL 687
ED + + K + EEL N + S+
Sbjct: 256 LEDELYAQKLKYKAISEELDHALNDMTSI 284
>AK131384-1|BAD18535.1| 326|Homo sapiens protein ( Homo sapiens
cDNA FLJ16459 fis, clone BRCAN2002473, moderately
similar to Tropomyosin, fibroblast isoform 2. ).
Length = 326
Score = 185 bits (451), Expect = 1e-46
Identities = 97/215 (45%), Positives = 145/215 (67%)
Frame = +1
Query: 73 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 252
A +K ++ + E+D +++ E A A K+ +E+ LQKKL E++L
Sbjct: 45 AKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKLEDELVSLQKKLKGTEDELDKYSE 104
Query: 253 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 432
L+ A + LE EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++ADE
Sbjct: 105 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 164
Query: 433 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 612
+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE+R
Sbjct: 165 SERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEER 224
Query: 613 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+ + K +ELEEELK V N+LKSLE EK +Q+
Sbjct: 225 AELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQK 259
Score = 103 bits (248), Expect = 5e-22
Identities = 65/226 (28%), Positives = 117/226 (51%), Gaps = 7/226 (3%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
MDAIKKKMQ +KL+K+NA+D+A+ E + A R++++ E++ +K L E++
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+L +A L E+ E E+ +L +K++ E++L+K E AQ+KL A++ A
Sbjct: 61 LEELHKAEDSLLAAEEAAAKLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKA 120
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-------E 585
+ L R Q EE +D+ +L A E+A+ +DE R + + E
Sbjct: 121 TDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDE 180
Query: 586 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+++E+ E ++K + + + + V L +E E+A +R E
Sbjct: 181 EKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAE 226
Score = 63.3 bits (147), Expect = 8e-10
Identities = 40/185 (21%), Positives = 98/185 (52%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 125 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 184
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ ++ K E ++
Sbjct: 185 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGKCAELEE 237
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
K LE +A++ ++ D+ ++K ++A+ +++ R + +E ++
Sbjct: 238 ELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 297
Query: 601 AEDRV 615
E++V
Sbjct: 298 LEEKV 302
>M19714-1|AAA61226.1| 264|Homo sapiens TPM1 protein.
Length = 264
Score = 182 bits (442), Expect = 2e-45
Identities = 93/197 (47%), Positives = 139/197 (70%)
Frame = +1
Query: 127 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTA 306
+A+ E + A R++++ +E+ LQKKL E++L L+ A + LE EK+ T
Sbjct: 1 RAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATD 60
Query: 307 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++ADE+ R KV+E+RAQ+DEE+
Sbjct: 61 AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEK 120
Query: 487 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 666
M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE+R + + K +ELEEELK V
Sbjct: 121 MEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTV 180
Query: 667 GNSLKSLEVSEEKANQR 717
N+LKSLE EK +Q+
Sbjct: 181 TNNLKSLEAQAEKYSQK 197
Score = 70.5 bits (165), Expect = 6e-12
Identities = 46/209 (22%), Positives = 107/209 (51%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 63 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 122
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ ++ K E ++
Sbjct: 123 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGKCAELEE 175
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
K LE +A++ ++ D+ ++K ++A+ +++ R + +E ++
Sbjct: 176 ELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 235
Query: 601 AEDRVKSGDAKISELEEELKVVGNSLKSL 687
ED + + K + EEL N + S+
Sbjct: 236 LEDELYAQKLKYKAISEELDHALNDMTSM 264
Score = 47.2 bits (107), Expect = 6e-05
Identities = 30/129 (23%), Positives = 63/129 (48%)
Frame = +1
Query: 337 KVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKE 516
+ +Q E D + +E+RS + +L+ Q+ K E+ + E + +L+
Sbjct: 1 RAEQAEADKKAAEDRSKQLEDELVSLQKKL-------KGTEDELDKYSEALKDAQEKLEL 53
Query: 517 ARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVS 696
A A DA+ ++R++ VE+EL+ A++R+ + K+ E E+ +K +E
Sbjct: 54 AEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESR 113
Query: 697 EEKANQRVE 723
+K +++E
Sbjct: 114 AQKDEEKME 122
>BC053545-1|AAH53545.1| 245|Homo sapiens tropomyosin 1 (alpha)
protein.
Length = 245
Score = 159 bits (387), Expect = 7e-39
Identities = 78/178 (43%), Positives = 124/178 (69%)
Frame = +1
Query: 184 NEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 363
+ + +++K+ ++E + + ++L+ + K EA+VA+LNR++Q +EE+L
Sbjct: 4 SSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEEL 63
Query: 364 EKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD 543
++++ER TA QKL EA+++ADE+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD
Sbjct: 64 DRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD 123
Query: 544 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
K +EV+RKL +E +LE AE+R + + K +ELEEELK V N+LKSLE EK +Q+
Sbjct: 124 RKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQK 181
Score = 66.5 bits (155), Expect = 9e-11
Identities = 45/204 (22%), Positives = 105/204 (51%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 47 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 106
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ ++ K E ++
Sbjct: 107 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGKCAELEE 159
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
K LE +A++ ++ D+ ++K ++A+ +++ R + +E ++
Sbjct: 160 ELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 219
Query: 601 AEDRVKSGDAKISELEEELKVVGN 672
ED++ + L ELK+ N
Sbjct: 220 LEDQLYQQLEQNRRLTNELKLALN 243
Score = 57.2 bits (132), Expect = 6e-08
Identities = 36/147 (24%), Positives = 72/147 (48%), Gaps = 7/147 (4%)
Frame = +1
Query: 304 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE 483
A + + A+ RK++ ++E + +EER+GT Q++L ++ + L R Q EE
Sbjct: 2 AGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEE 61
Query: 484 RMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-------EDELEVAEDRVKSGDAKISE 642
+D+ +L A E+A+ +DE R + + E+++E+ E ++K +
Sbjct: 62 ELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAED 121
Query: 643 LEEELKVVGNSLKSLEVSEEKANQRVE 723
+ + + V L +E E+A +R E
Sbjct: 122 ADRKYEEVARKLVIIESDLERAEERAE 148
Score = 49.2 bits (112), Expect = 1e-05
Identities = 27/106 (25%), Positives = 52/106 (49%)
Frame = +1
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
+ S + R + L+ +A EER L +L R L E A+ ++R++ VE
Sbjct: 1 MAGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVE 60
Query: 586 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+EL+ A++R+ + K+ E E+ +K +E +K +++E
Sbjct: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 106
>BC050473-1|AAH50473.1| 287|Homo sapiens TPM1 protein protein.
Length = 287
Score = 159 bits (387), Expect = 7e-39
Identities = 78/178 (43%), Positives = 124/178 (69%)
Frame = +1
Query: 184 NEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 363
+ + +++K+ ++E + + ++L+ + K EA+VA+LNR++Q +EE+L
Sbjct: 46 SSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEEL 105
Query: 364 EKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD 543
++++ER TA QKL EA+++ADE+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD
Sbjct: 106 DRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD 165
Query: 544 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
K +EV+RKL +E +LE AE+R + + K +ELEEELK V N+LKSLE EK +Q+
Sbjct: 166 RKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQK 223
Score = 66.5 bits (155), Expect = 9e-11
Identities = 45/204 (22%), Positives = 105/204 (51%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 89 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 148
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ ++ K E ++
Sbjct: 149 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGKCAELEE 201
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
K LE +A++ ++ D+ ++K ++A+ +++ R + +E ++
Sbjct: 202 ELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 261
Query: 601 AEDRVKSGDAKISELEEELKVVGN 672
ED++ + L ELK+ N
Sbjct: 262 LEDQLYQQLEQNRRLTNELKLALN 285
Score = 57.2 bits (132), Expect = 6e-08
Identities = 36/147 (24%), Positives = 72/147 (48%), Gaps = 7/147 (4%)
Frame = +1
Query: 304 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE 483
A + + A+ RK++ ++E + +EER+GT Q++L ++ + L R Q EE
Sbjct: 44 AGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEE 103
Query: 484 RMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-------EDELEVAEDRVKSGDAKISE 642
+D+ +L A E+A+ +DE R + + E+++E+ E ++K +
Sbjct: 104 ELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAED 163
Query: 643 LEEELKVVGNSLKSLEVSEEKANQRVE 723
+ + + V L +E E+A +R E
Sbjct: 164 ADRKYEEVARKLVIIESDLERAEERAE 190
Score = 49.2 bits (112), Expect = 1e-05
Identities = 27/106 (25%), Positives = 52/106 (49%)
Frame = +1
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
+ S + R + L+ +A EER L +L R L E A+ ++R++ VE
Sbjct: 43 MAGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVE 102
Query: 586 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+EL+ A++R+ + K+ E E+ +K +E +K +++E
Sbjct: 103 EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 148
>AB209041-1|BAD92278.1| 303|Homo sapiens TPM1 protein variant
protein.
Length = 303
Score = 157 bits (380), Expect = 5e-38
Identities = 77/178 (43%), Positives = 123/178 (69%)
Frame = +1
Query: 184 NEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 363
+ + +++K+ ++E + + ++L+ + K EA+VA+LNR++Q +EE+L
Sbjct: 62 SSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEEL 121
Query: 364 EKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD 543
++++ER TA QKL EA+++AD + R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD
Sbjct: 122 DRAQERLATALQKLEEAEKAADGSERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD 181
Query: 544 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
K +EV+RKL +E +LE AE+R + + K +ELEEELK V N+LKSLE EK +Q+
Sbjct: 182 RKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQK 239
Score = 65.3 bits (152), Expect = 2e-10
Identities = 45/204 (22%), Positives = 104/204 (50%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A + ++ +++Q ++ E D A ++ T Q+ +A A+ ++ ++ + + EE +
Sbjct: 105 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADGSERGMKVIESRAQKDEEKME 164
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ ++ K E ++
Sbjct: 165 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGKCAELEE 217
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
K LE +A++ ++ D+ ++K ++A+ +++ R + +E ++
Sbjct: 218 ELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 277
Query: 601 AEDRVKSGDAKISELEEELKVVGN 672
ED++ + L ELK+ N
Sbjct: 278 LEDQLYQQLEQNRRLTNELKLALN 301
Score = 55.2 bits (127), Expect = 2e-07
Identities = 35/147 (23%), Positives = 73/147 (49%), Gaps = 7/147 (4%)
Frame = +1
Query: 304 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL-----LEAQQSAD--ENNRMCKVLEN 462
A + + A+ RK++ ++E + +EER+GT Q++L L AD NR +++E
Sbjct: 60 AGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEE 119
Query: 463 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE 642
+ +ER+ +L+EA A+ ++ + + E+++E+ E ++K +
Sbjct: 120 ELDRAQERLATALQKLEEAEKAADGSERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAED 179
Query: 643 LEEELKVVGNSLKSLEVSEEKANQRVE 723
+ + + V L +E E+A +R E
Sbjct: 180 ADRKYEEVARKLVIIESDLERAEERAE 206
Score = 48.8 bits (111), Expect = 2e-05
Identities = 27/106 (25%), Positives = 52/106 (49%)
Frame = +1
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
+ S + R + L+ +A EER L +L R L E A+ ++R++ VE
Sbjct: 59 MAGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVE 118
Query: 586 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+EL+ A++R+ + K+ E E+ +K +E +K +++E
Sbjct: 119 EELDRAQERLATALQKLEEAEKAADGSERGMKVIESRAQKDEEKME 164
>AL590431-10|CAH71268.1| 247|Homo sapiens tropomyosin 3 protein.
Length = 247
Score = 156 bits (378), Expect = 9e-38
Identities = 77/175 (44%), Positives = 124/175 (70%)
Frame = +1
Query: 193 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 372
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 373 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 552
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+EV+RKL +E +LE E+R + ++K SELEEELK V N+LKSLE EK +Q+
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQK 181
Score = 83.4 bits (197), Expect = 7e-16
Identities = 57/219 (26%), Positives = 107/219 (48%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDR 65
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRK 125
Query: 424 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 603
+E R ++E ++ EER AE A+ K E+ +L V + L+
Sbjct: 126 YEEVARKLVIIEGDLERTEER--------------AELAESKCSELEEELKNVTNNLKSL 171
Query: 604 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
E + + K + EEE+K++ + LK E E A + V
Sbjct: 172 EAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSV 210
Score = 73.3 bits (172), Expect = 8e-13
Identities = 51/210 (24%), Positives = 110/210 (52%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+Q A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + E
Sbjct: 43 EQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDE 102
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
E + L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ K
Sbjct: 103 EKMELQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESKCS 155
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
E ++ K LE +A++ ++ D+ ++K ++A+ +++ R +A +E
Sbjct: 156 ELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
Query: 589 ELEVAEDRVKSGDAKISELEEELKVVGNSL 678
++ E+R+ S + L ELK+ + L
Sbjct: 216 TIDDLEERLYSQLERNRLLSNELKLTLHDL 245
>AL590431-9|CAH71267.1| 248|Homo sapiens tropomyosin 3 protein.
Length = 248
Score = 156 bits (378), Expect = 9e-38
Identities = 77/175 (44%), Positives = 124/175 (70%)
Frame = +1
Query: 193 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 372
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 373 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 552
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+EV+RKL +E +LE E+R + ++K SELEEELK V N+LKSLE EK +Q+
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQK 181
Score = 85.0 bits (201), Expect = 2e-16
Identities = 57/233 (24%), Positives = 113/233 (48%), Gaps = 14/233 (6%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDR 65
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRK 125
Query: 424 ADENNRMCKVLENRAQQDEER--------------MDQLTNQLKEARLLAEDADGKSDEV 561
+E R ++E ++ EER + +TN LK AE K D+
Sbjct: 126 YEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKY 185
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
++ + D+L+ AE R + + +++LE+ + + + LK + E QR+
Sbjct: 186 EEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTK-EEHLCTQRM 237
Score = 69.7 bits (163), Expect = 1e-11
Identities = 50/194 (25%), Positives = 104/194 (53%), Gaps = 7/194 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+Q A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + E
Sbjct: 43 EQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDE 102
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
E + L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ K
Sbjct: 103 EKMELQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESKCS 155
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQ-------LTNQLKEARLLAEDADGKSDEVSR 567
E ++ K LE +A++ ++ D+ LT++LKEA AE A+ ++ +
Sbjct: 156 ELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
Query: 568 KLAFVEDELEVAED 609
+ +ED+L+ ++
Sbjct: 216 TIDDLEDKLKCTKE 229
>Z24727-1|CAA80853.1| 243|Homo sapiens tropomyosin isoform protein.
Length = 243
Score = 155 bits (376), Expect = 2e-37
Identities = 75/164 (45%), Positives = 121/164 (73%)
Frame = +1
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
E++L L+ A + LE EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL
Sbjct: 17 EDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKL 76
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
EA+++ADE+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E
Sbjct: 77 EEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIE 136
Query: 586 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+LE AE+R + + ++ +LEE+L+++ +LK+L +E+K +Q+
Sbjct: 137 SDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQK 180
Score = 64.9 bits (151), Expect = 3e-10
Identities = 55/216 (25%), Positives = 104/216 (48%), Gaps = 7/216 (3%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T D + K +A+K +A +K + E++A DA +V L +++ VEE+L
Sbjct: 16 TEDELDKYSEALK----DAQEKLELAEKKATDAEA-------DVASLNRRIQLVEEELDR 64
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
+ +L A + LEE EK +E + + + Q+ EE +E E + A+ +A +
Sbjct: 65 AQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRK 124
Query: 424 ADENNRMCKVLENRAQQDEERMDQLTNQLK--EARLLAEDADGKS-----DEVSRKLAFV 582
+E R ++E+ ++ EER + Q++ E +L D K+ D+ S+K
Sbjct: 125 YEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRY 184
Query: 583 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
E+E++V D++K + + E + + S+ LE
Sbjct: 185 EEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLE 220
Score = 59.3 bits (137), Expect = 1e-08
Identities = 45/185 (24%), Positives = 100/185 (54%), Gaps = 7/185 (3%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 46 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 105
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEA 414
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ Q + LE
Sbjct: 106 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGQVRQLEE 158
Query: 415 Q-QSADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAF 579
Q + D+ + E++ Q E+R ++ L+++LKEA AE A+ ++ + +
Sbjct: 159 QLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 218
Query: 580 VEDEL 594
+E+++
Sbjct: 219 LEEKV 223
Score = 39.9 bits (89), Expect = 0.009
Identities = 22/92 (23%), Positives = 46/92 (50%)
Frame = +1
Query: 448 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 627
K E+ + E + +L+ A A DA+ ++R++ VE+EL+ A++R+ +
Sbjct: 14 KGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATAL 73
Query: 628 AKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
K+ E E+ +K +E +K +++E
Sbjct: 74 QKLEEAEKAADESERGMKVIESRAQKDEEKME 105
>M19715-1|AAA61227.1| 229|Homo sapiens TPM1 protein.
Length = 229
Score = 153 bits (371), Expect = 6e-37
Identities = 73/154 (47%), Positives = 117/154 (75%)
Frame = +1
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
L+ A + LE EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++ADE+
Sbjct: 9 LKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 68
Query: 436 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 615
R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE+R
Sbjct: 69 ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERA 128
Query: 616 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+ + ++ +LEE+L+++ +LK+L +E+K +Q+
Sbjct: 129 ELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQK 162
Score = 62.5 bits (145), Expect = 1e-09
Identities = 48/202 (23%), Positives = 94/202 (46%), Gaps = 7/202 (3%)
Frame = +1
Query: 106 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEE 285
E D + +++ A +A +V L +++ VEE+L + +L A + LEE
Sbjct: 1 ELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 60
Query: 286 KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 465
EK +E + + + Q+ EE +E E + A+ +A + +E R ++E+
Sbjct: 61 AEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESD 120
Query: 466 AQQDEERMDQLTNQLK--EARLLAEDADGKS-----DEVSRKLAFVEDELEVAEDRVKSG 624
++ EER + Q++ E +L D K+ D+ S+K E+E++V D++K
Sbjct: 121 LERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEA 180
Query: 625 DAKISELEEELKVVGNSLKSLE 690
+ + E + + S+ LE
Sbjct: 181 ETRAEFAERSVTKLEKSIDDLE 202
Score = 60.5 bits (140), Expect = 6e-09
Identities = 46/190 (24%), Positives = 103/190 (54%), Gaps = 7/190 (3%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 28 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 87
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEA 414
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ Q + LE
Sbjct: 88 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGQVRQLEE 140
Query: 415 Q-QSADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAF 579
Q + D+ + E++ Q E+R ++ L+++LKEA AE A+ ++ + +
Sbjct: 141 QLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 200
Query: 580 VEDELEVAED 609
+E+++ A++
Sbjct: 201 LEEKVAHAKE 210
Score = 38.3 bits (85), Expect = 0.028
Identities = 20/81 (24%), Positives = 42/81 (51%)
Frame = +1
Query: 481 ERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 660
E + +L+ A A DA+ ++R++ VE+EL+ A++R+ + K+ E E+
Sbjct: 7 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 66
Query: 661 VVGNSLKSLEVSEEKANQRVE 723
+K +E +K +++E
Sbjct: 67 ESERGMKVIESRAQKDEEKME 87
Score = 32.3 bits (70), Expect = 1.8
Identities = 21/104 (20%), Positives = 51/104 (49%), Gaps = 7/104 (6%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQ-------KKLAQVE 228
+ + +K+ ++ + + A ++A+ E Q R + +++ ++ L +K + E
Sbjct: 108 EEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYE 167
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEED 360
E++ + +KL++A E E+ +T E + L KV +E+
Sbjct: 168 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 211
>X05276-1|CAA28888.1| 248|Homo sapiens protein ( Human mRNA for
fibroblast tropomyosin TM30 (pl). ).
Length = 248
Score = 151 bits (367), Expect = 2e-36
Identities = 74/172 (43%), Positives = 123/172 (71%)
Frame = +1
Query: 202 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 381
+++K+ +++ +++ + ++L+ + ++ E +VAALNR++Q +EE+L++++ER
Sbjct: 10 VKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQER 69
Query: 382 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 561
TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV
Sbjct: 70 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 129
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+RKL +E ELE AE+R + + K +LEEELK V N+LKSLE + EK +++
Sbjct: 130 ARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEK 181
Score = 84.2 bits (199), Expect = 4e-16
Identities = 54/212 (25%), Positives = 104/212 (49%), Gaps = 14/212 (6%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
+++A+K+K+QA++ + D A D+A +++ R EK +V L +++ VEE+L
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDR 65
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRK 125
Query: 424 ADENNRMCKVLENRAQQDEER--------------MDQLTNQLKEARLLAEDADGKSDEV 561
+E R +LE ++ EER + +TN LK +E K D+
Sbjct: 126 YEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKY 185
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEEEL 657
++ + D+L+ AE R + + +++LE+ +
Sbjct: 186 EEEIKLLSDKLKEAETRAEFAERTVAKLEKTI 217
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/96 (28%), Positives = 51/96 (53%)
Frame = +1
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
S + R + L+ +A + E+R L +L R E A+G ++R++ VE+EL+
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDR 65
Query: 601 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
A++R+ + + +LEE K S + ++V E +A
Sbjct: 66 AQERLATA---LQKLEEAEKAADESERGMKVIENRA 98
>BT019634-1|AAV38440.1| 248|Homo sapiens tropomyosin 4 protein.
Length = 248
Score = 151 bits (367), Expect = 2e-36
Identities = 74/172 (43%), Positives = 123/172 (71%)
Frame = +1
Query: 202 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 381
+++K+ +++ +++ + ++L+ + ++ E +VAALNR++Q +EE+L++++ER
Sbjct: 10 VKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQER 69
Query: 382 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 561
TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV
Sbjct: 70 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 129
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+RKL +E ELE AE+R + + K +LEEELK V N+LKSLE + EK +++
Sbjct: 130 ARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEK 181
Score = 84.2 bits (199), Expect = 4e-16
Identities = 54/212 (25%), Positives = 104/212 (49%), Gaps = 14/212 (6%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
+++A+K+K+QA++ + D A D+A +++ R EK +V L +++ VEE+L
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDR 65
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRK 125
Query: 424 ADENNRMCKVLENRAQQDEER--------------MDQLTNQLKEARLLAEDADGKSDEV 561
+E R +LE ++ EER + +TN LK +E K D+
Sbjct: 126 YEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKY 185
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEEEL 657
++ + D+L+ AE R + + +++LE+ +
Sbjct: 186 EEEIKLLSDKLKEAETRAEFAERTVAKLEKTI 217
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/96 (28%), Positives = 51/96 (53%)
Frame = +1
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
S + R + L+ +A + E+R L +L R E A+G ++R++ VE+EL+
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDR 65
Query: 601 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
A++R+ + + +LEE K S + ++V E +A
Sbjct: 66 AQERLATA---LQKLEEAEKAADESERGMKVIENRA 98
>BC067225-1|AAH67225.1| 248|Homo sapiens tropomyosin 4 protein.
Length = 248
Score = 151 bits (367), Expect = 2e-36
Identities = 74/172 (43%), Positives = 123/172 (71%)
Frame = +1
Query: 202 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 381
+++K+ +++ +++ + ++L+ + ++ E +VAALNR++Q +EE+L++++ER
Sbjct: 10 VKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQER 69
Query: 382 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 561
TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV
Sbjct: 70 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 129
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+RKL +E ELE AE+R + + K +LEEELK V N+LKSLE + EK +++
Sbjct: 130 ARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEK 181
Score = 84.2 bits (199), Expect = 4e-16
Identities = 54/212 (25%), Positives = 104/212 (49%), Gaps = 14/212 (6%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
+++A+K+K+QA++ + D A D+A +++ R EK +V L +++ VEE+L
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDR 65
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRK 125
Query: 424 ADENNRMCKVLENRAQQDEER--------------MDQLTNQLKEARLLAEDADGKSDEV 561
+E R +LE ++ EER + +TN LK +E K D+
Sbjct: 126 YEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKY 185
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEEEL 657
++ + D+L+ AE R + + +++LE+ +
Sbjct: 186 EEEIKLLSDKLKEAETRAEFAERTVAKLEKTI 217
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/96 (28%), Positives = 51/96 (53%)
Frame = +1
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
S + R + L+ +A + E+R L +L R E A+G ++R++ VE+EL+
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDR 65
Query: 601 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
A++R+ + + +LEE K S + ++V E +A
Sbjct: 66 AQERLATA---LQKLEEAEKAADESERGMKVIENRA 98
>BC037576-1|AAH37576.1| 248|Homo sapiens tropomyosin 4 protein.
Length = 248
Score = 151 bits (367), Expect = 2e-36
Identities = 74/172 (43%), Positives = 123/172 (71%)
Frame = +1
Query: 202 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 381
+++K+ +++ +++ + ++L+ + ++ E +VAALNR++Q +EE+L++++ER
Sbjct: 10 VKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQER 69
Query: 382 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 561
TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV
Sbjct: 70 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 129
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+RKL +E ELE AE+R + + K +LEEELK V N+LKSLE + EK +++
Sbjct: 130 ARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEK 181
Score = 84.2 bits (199), Expect = 4e-16
Identities = 54/212 (25%), Positives = 104/212 (49%), Gaps = 14/212 (6%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
+++A+K+K+QA++ + D A D+A +++ R EK +V L +++ VEE+L
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDR 65
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRK 125
Query: 424 ADENNRMCKVLENRAQQDEER--------------MDQLTNQLKEARLLAEDADGKSDEV 561
+E R +LE ++ EER + +TN LK +E K D+
Sbjct: 126 YEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKY 185
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEEEL 657
++ + D+L+ AE R + + +++LE+ +
Sbjct: 186 EEEIKLLSDKLKEAETRAEFAERTVAKLEKTI 217
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/96 (28%), Positives = 51/96 (53%)
Frame = +1
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
S + R + L+ +A + E+R L +L R E A+G ++R++ VE+EL+
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDR 65
Query: 601 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
A++R+ + + +LEE K S + ++V E +A
Sbjct: 66 AQERLATA---LQKLEEAEKAADESERGMKVIENRA 98
>AF310722-1|AAK17926.1| 320|Homo sapiens tropomyosin 4-anaplastic
lymphoma kinase fusion protein protein.
Length = 320
Score = 151 bits (367), Expect = 2e-36
Identities = 74/172 (43%), Positives = 123/172 (71%)
Frame = +1
Query: 202 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 381
+++K+ +++ +++ + ++L+ + ++ E +VAALNR++Q +EE+L++++ER
Sbjct: 10 VKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQER 69
Query: 382 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 561
TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV
Sbjct: 70 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 129
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+RKL +E ELE AE+R + + K +LEEELK V N+LKSLE + EK +++
Sbjct: 130 ARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEK 181
Score = 85.4 bits (202), Expect = 2e-16
Identities = 55/221 (24%), Positives = 107/221 (48%), Gaps = 7/221 (3%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
+++A+K+K+QA++ + D A D+A +++ R EK +V L +++ VEE+L
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDR 65
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRK 125
Query: 424 ADENNRMCKVLENRAQQDEERMD-------QLTNQLKEARLLAEDADGKSDEVSRKLAFV 582
+E R +LE ++ EER + L +LK + + S++ S K
Sbjct: 126 YEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKY 185
Query: 583 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
E+E+++ D++K + + E + + ++ LEV K
Sbjct: 186 EEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEVYRRK 226
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/96 (28%), Positives = 51/96 (53%)
Frame = +1
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
S + R + L+ +A + E+R L +L R E A+G ++R++ VE+EL+
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDR 65
Query: 601 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
A++R+ + + +LEE K S + ++V E +A
Sbjct: 66 AQERLATA---LQKLEEAEKAADESERGMKVIENRA 98
>AF186109-1|AAG17014.1| 237|Homo sapiens TPM4-ALK fusion
oncoprotein type 2 protein.
Length = 237
Score = 151 bits (367), Expect = 2e-36
Identities = 74/172 (43%), Positives = 123/172 (71%)
Frame = +1
Query: 202 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 381
+++K+ +++ +++ + ++L+ + ++ E +VAALNR++Q +EE+L++++ER
Sbjct: 10 VKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQER 69
Query: 382 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 561
TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV
Sbjct: 70 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 129
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+RKL +E ELE AE+R + + K +LEEELK V N+LKSLE + EK +++
Sbjct: 130 ARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEK 181
Score = 85.4 bits (202), Expect = 2e-16
Identities = 55/221 (24%), Positives = 107/221 (48%), Gaps = 7/221 (3%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
+++A+K+K+QA++ + D A D+A +++ R EK +V L +++ VEE+L
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDR 65
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRK 125
Query: 424 ADENNRMCKVLENRAQQDEERMD-------QLTNQLKEARLLAEDADGKSDEVSRKLAFV 582
+E R +LE ++ EER + L +LK + + S++ S K
Sbjct: 126 YEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKY 185
Query: 583 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
E+E+++ D++K + + E + + ++ LEV K
Sbjct: 186 EEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEVYRRK 226
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/96 (28%), Positives = 51/96 (53%)
Frame = +1
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
S + R + L+ +A + E+R L +L R E A+G ++R++ VE+EL+
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDR 65
Query: 601 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
A++R+ + + +LEE K S + ++V E +A
Sbjct: 66 AQERLATA---LQKLEEAEKAADESERGMKVIENRA 98
>DQ424903-1|ABD83668.1| 245|Homo sapiens tropomyosin 1 alpha
variant 6 protein.
Length = 245
Score = 151 bits (365), Expect = 3e-36
Identities = 70/178 (39%), Positives = 125/178 (70%)
Frame = +1
Query: 184 NEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 363
+ + +++K+ ++E + + ++L+ + K EA+VA+LNR++Q +EE+L
Sbjct: 4 SSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEEL 63
Query: 364 EKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD 543
++++ER TA QKL EA+++ADE+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD
Sbjct: 64 DRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD 123
Query: 544 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
K +EV+RKL +E +LE AE+R + + ++ +LEE+L+++ +LK+L +E+K +Q+
Sbjct: 124 RKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQK 181
Score = 74.5 bits (175), Expect = 3e-13
Identities = 51/218 (23%), Positives = 110/218 (50%), Gaps = 7/218 (3%)
Frame = +1
Query: 58 AATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL 237
+++++A+++K+++++ + D A ++A T +++ E +V L +++ VEE+L
Sbjct: 4 SSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEEL 63
Query: 238 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 417
+ +L A + LEE EK +E + + + Q+ EE +E E + A+ +A
Sbjct: 64 DRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD 123
Query: 418 QSADENNRMCKVLENRAQQDEERMDQLTNQLK--EARLLAEDADGKS-----DEVSRKLA 576
+ +E R ++E+ ++ EER + Q++ E +L D K+ D+ S+K
Sbjct: 124 RKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKED 183
Query: 577 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
E+E++V D+ K + + E + + S+ LE
Sbjct: 184 RYEEEIKVLSDKPKEAETRAEFAERSVTKLEKSIDDLE 221
Score = 60.9 bits (141), Expect = 5e-09
Identities = 49/206 (23%), Positives = 111/206 (53%), Gaps = 9/206 (4%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 47 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 106
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEA 414
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ Q + LE
Sbjct: 107 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGQVRQLEE 159
Query: 415 Q-QSADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAF 579
Q + D+ + E++ Q E+R ++ L+++ KEA AE A+ ++ + +
Sbjct: 160 QLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKPKEAETRAEFAERSVTKLEKSIDD 219
Query: 580 VEDEL--EVAEDRVKSGDAKISELEE 651
+ED+L ++ ++R + + K++ E+
Sbjct: 220 LEDQLYQQLEQNRRLTNELKLALNED 245
Score = 57.2 bits (132), Expect = 6e-08
Identities = 36/147 (24%), Positives = 72/147 (48%), Gaps = 7/147 (4%)
Frame = +1
Query: 304 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE 483
A + + A+ RK++ ++E + +EER+GT Q++L ++ + L R Q EE
Sbjct: 2 AGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEE 61
Query: 484 RMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-------EDELEVAEDRVKSGDAKISE 642
+D+ +L A E+A+ +DE R + + E+++E+ E ++K +
Sbjct: 62 ELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAED 121
Query: 643 LEEELKVVGNSLKSLEVSEEKANQRVE 723
+ + + V L +E E+A +R E
Sbjct: 122 ADRKYEEVARKLVIIESDLERAEERAE 148
Score = 49.2 bits (112), Expect = 1e-05
Identities = 27/106 (25%), Positives = 52/106 (49%)
Frame = +1
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
+ S + R + L+ +A EER L +L R L E A+ ++R++ VE
Sbjct: 1 MAGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVE 60
Query: 586 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+EL+ A++R+ + K+ E E+ +K +E +K +++E
Sbjct: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 106
>BC002827-1|AAH02827.1| 248|Homo sapiens tropomyosin 4 protein.
Length = 248
Score = 150 bits (364), Expect = 4e-36
Identities = 74/172 (43%), Positives = 122/172 (70%)
Frame = +1
Query: 202 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 381
+++K+ +++ +++ + ++L+ + ++ E +VAALNR++Q EE+L++++ER
Sbjct: 10 VKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLFEEELDRAQER 69
Query: 382 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 561
TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV
Sbjct: 70 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 129
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+RKL +E ELE AE+R + + K +LEEELK V N+LKSLE + EK +++
Sbjct: 130 ARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEK 181
Score = 82.2 bits (194), Expect = 2e-15
Identities = 53/212 (25%), Positives = 103/212 (48%), Gaps = 14/212 (6%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
+++A+K+K+QA++ + D A D+A +++ R EK +V L +++ EE+L
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLFEEELDR 65
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRK 125
Query: 424 ADENNRMCKVLENRAQQDEER--------------MDQLTNQLKEARLLAEDADGKSDEV 561
+E R +LE ++ EER + +TN LK +E K D+
Sbjct: 126 YEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKY 185
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEEEL 657
++ + D+L+ AE R + + +++LE+ +
Sbjct: 186 EEEIKLLSDKLKEAETRAEFAERTVAKLEKTI 217
Score = 43.6 bits (98), Expect = 7e-04
Identities = 26/96 (27%), Positives = 50/96 (52%)
Frame = +1
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
S + R + L+ +A + E+R L +L R E A+G ++R++ E+EL+
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLFEEELDR 65
Query: 601 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
A++R+ + + +LEE K S + ++V E +A
Sbjct: 66 AQERLATA---LQKLEEAEKAADESERGMKVIENRA 98
>AL590431-11|CAH71270.1| 242|Homo sapiens tropomyosin 3 protein.
Length = 242
Score = 149 bits (360), Expect = 1e-35
Identities = 79/177 (44%), Positives = 121/177 (68%)
Frame = +1
Query: 187 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE 366
E +++ + L +E+ + + E K EE+ KQL E E+AA+ +K++ E++L+
Sbjct: 2 EAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQL---EDELAAMQKKLKGTEDELD 58
Query: 367 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 546
+++ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD
Sbjct: 59 RAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADR 118
Query: 547 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
K +EV+RKL +E +LE E+R + ++K SELEEELK V N+LKSLE EK +Q+
Sbjct: 119 KYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQK 175
Score = 102 bits (244), Expect = 1e-21
Identities = 67/231 (29%), Positives = 119/231 (51%), Gaps = 19/231 (8%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
M+AIKKKMQ +KL+K+NA+D+A+ E + + A R++++ +E+ +QKKL E++L
Sbjct: 1 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDRA 60
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 61 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 120
Query: 427 DENNRMCKVLENRAQQDEER--------------MDQLTNQLKEARLLAEDADGKSDEVS 564
+E R ++E ++ EER + +TN LK AE K D+
Sbjct: 121 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 180
Query: 565 RKLAFVEDELEVAEDRVKSGDAKISELEE-----ELKVVGNSLKSLEVSEE 702
++ + D+L+ AE R + + +++LE+ E ++ LK +SEE
Sbjct: 181 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEE 231
>AK092690-1|BAC03946.1| 243|Homo sapiens protein ( Homo sapiens
cDNA FLJ35371 fis, clone SKMUS2001740, highly similar to
TROPOMYOSIN ALPHA CHAIN, SKELETAL MUSCLE TYPE. ).
Length = 243
Score = 149 bits (360), Expect = 1e-35
Identities = 79/177 (44%), Positives = 121/177 (68%)
Frame = +1
Query: 187 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE 366
E +++ + L +E+ + + E K EE+ KQL E E+AA+ +K++ E++L+
Sbjct: 3 EAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQL---EDELAAMQKKLKGTEDELD 59
Query: 367 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 546
+++ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD
Sbjct: 60 RAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADR 119
Query: 547 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
K +EV+RKL +E +LE E+R + ++K SELEEELK V N+LKSLE EK +Q+
Sbjct: 120 KYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQK 176
Score = 102 bits (244), Expect = 1e-21
Identities = 67/231 (29%), Positives = 119/231 (51%), Gaps = 19/231 (8%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
M+AIKKKMQ +KL+K+NA+D+A+ E + + A R++++ +E+ +QKKL E++L
Sbjct: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDRA 61
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 62 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 121
Query: 427 DENNRMCKVLENRAQQDEER--------------MDQLTNQLKEARLLAEDADGKSDEVS 564
+E R ++E ++ EER + +TN LK AE K D+
Sbjct: 122 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 181
Query: 565 RKLAFVEDELEVAEDRVKSGDAKISELEE-----ELKVVGNSLKSLEVSEE 702
++ + D+L+ AE R + + +++LE+ E ++ LK +SEE
Sbjct: 182 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEE 232
>AF474156-1|AAL84569.1| 203|Homo sapiens TPMsk1 protein.
Length = 203
Score = 149 bits (360), Expect = 1e-35
Identities = 70/148 (47%), Positives = 113/148 (76%)
Frame = +1
Query: 274 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV 453
D E K ++ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++ADE+ R KV
Sbjct: 1 DHERKLRETTDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKV 60
Query: 454 LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAK 633
+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE+R + + +
Sbjct: 61 IESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQ 120
Query: 634 ISELEEELKVVGNSLKSLEVSEEKANQR 717
+ +LEE+L+++ +LK+L +E+K +Q+
Sbjct: 121 VRQLEEQLRIMDQTLKALMAAEDKYSQK 148
Score = 64.1 bits (149), Expect = 5e-10
Identities = 49/194 (25%), Positives = 104/194 (53%), Gaps = 7/194 (3%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 14 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 73
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEA 414
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ Q + LE
Sbjct: 74 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGQVRQLEE 126
Query: 415 Q-QSADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAF 579
Q + D+ + E++ Q E+R ++ L+++LKEA AE A+ ++ + +
Sbjct: 127 QLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 186
Query: 580 VEDELEVAEDRVKS 621
+EDEL + + K+
Sbjct: 187 LEDELYAQKLKYKA 200
Score = 36.3 bits (80), Expect = 0.11
Identities = 20/70 (28%), Positives = 38/70 (54%), Gaps = 2/70 (2%)
Frame = +1
Query: 520 RLLAEDADGKSDEVS--RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 693
R L E D ++D S R++ VE+EL+ A++R+ + K+ E E+ +K +E
Sbjct: 4 RKLRETTDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIES 63
Query: 694 SEEKANQRVE 723
+K +++E
Sbjct: 64 RAQKDEEKME 73
>X04588-1|CAB37185.1| 248|Homo sapiens protein ( Human 2.5 kb mRNA
for cytoskeletal tropomyosin TM30(nm). ).
Length = 248
Score = 144 bits (350), Expect = 2e-34
Identities = 67/175 (38%), Positives = 123/175 (70%)
Frame = +1
Query: 193 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 372
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 373 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 552
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+EV+RKL +E +LE E+R + +++ E++E+++++ +LK L +EEK +Q+
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQK 181
Score = 78.2 bits (184), Expect = 3e-14
Identities = 49/216 (22%), Positives = 108/216 (50%), Gaps = 7/216 (3%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDR 65
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRK 125
Query: 424 ADENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFV 582
+E R ++E ++ EER + ++ +E RL+ ++ ++ S+K
Sbjct: 126 YEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKY 185
Query: 583 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
E+E+++ D++K + + E + + ++ LE
Sbjct: 186 EEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 221
Score = 69.7 bits (163), Expect = 1e-11
Identities = 49/194 (25%), Positives = 104/194 (53%), Gaps = 7/194 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+Q A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + E
Sbjct: 43 EQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDE 102
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
E + L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ +
Sbjct: 103 EKMELQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESRCR 155
Query: 409 EAQQS---ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSR 567
E + D+N + E + Q E++ ++ LT++LKEA AE A+ ++ +
Sbjct: 156 EMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
Query: 568 KLAFVEDELEVAED 609
+ +ED+L+ ++
Sbjct: 216 TIDDLEDKLKCTKE 229
Score = 60.9 bits (141), Expect = 5e-09
Identities = 37/198 (18%), Positives = 89/198 (44%)
Frame = +1
Query: 127 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTA 306
K +QQA DA RAE++ EV ++ Q E ++ +++ ++L+ +++L
Sbjct: 13 KIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLAT 72
Query: 307 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
++ + + E ++ E R+ ++K+ + E + + + + ++ +
Sbjct: 73 ALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARK 132
Query: 487 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 666
+ + L+ AE A+ + E+ ++ ++ L+ + K + EEE+K++
Sbjct: 133 LVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKIL 192
Query: 667 GNSLKSLEVSEEKANQRV 720
+ LK E E A + V
Sbjct: 193 TDKLKEAETRAEFAERSV 210
>BC072428-1|AAH72428.1| 248|Homo sapiens tropomyosin 3 protein.
Length = 248
Score = 144 bits (350), Expect = 2e-34
Identities = 67/175 (38%), Positives = 123/175 (70%)
Frame = +1
Query: 193 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 372
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 373 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 552
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+EV+RKL +E +LE E+R + +++ E++E+++++ +LK L +EEK +Q+
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQK 181
Score = 78.2 bits (184), Expect = 3e-14
Identities = 49/216 (22%), Positives = 108/216 (50%), Gaps = 7/216 (3%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDR 65
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRK 125
Query: 424 ADENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFV 582
+E R ++E ++ EER + ++ +E RL+ ++ ++ S+K
Sbjct: 126 YEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKY 185
Query: 583 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
E+E+++ D++K + + E + + ++ LE
Sbjct: 186 EEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 221
Score = 69.7 bits (163), Expect = 1e-11
Identities = 49/194 (25%), Positives = 104/194 (53%), Gaps = 7/194 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+Q A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + E
Sbjct: 43 EQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDE 102
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
E + L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ +
Sbjct: 103 EKMELQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESRCR 155
Query: 409 EAQQS---ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSR 567
E + D+N + E + Q E++ ++ LT++LKEA AE A+ ++ +
Sbjct: 156 EMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
Query: 568 KLAFVEDELEVAED 609
+ +ED+L+ ++
Sbjct: 216 TIDDLEDKLKCTKE 229
Score = 60.9 bits (141), Expect = 5e-09
Identities = 37/198 (18%), Positives = 89/198 (44%)
Frame = +1
Query: 127 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTA 306
K +QQA DA RAE++ EV ++ Q E ++ +++ ++L+ +++L
Sbjct: 13 KIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLAT 72
Query: 307 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
++ + + E ++ E R+ ++K+ + E + + + + ++ +
Sbjct: 73 ALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARK 132
Query: 487 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 666
+ + L+ AE A+ + E+ ++ ++ L+ + K + EEE+K++
Sbjct: 133 LVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKIL 192
Query: 667 GNSLKSLEVSEEKANQRV 720
+ LK E E A + V
Sbjct: 193 TDKLKEAETRAEFAERSV 210
>BC015403-1|AAH15403.1| 248|Homo sapiens tropomyosin 3 protein.
Length = 248
Score = 144 bits (350), Expect = 2e-34
Identities = 67/175 (38%), Positives = 123/175 (70%)
Frame = +1
Query: 193 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 372
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 373 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 552
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+EV+RKL +E +LE E+R + +++ E++E+++++ +LK L +EEK +Q+
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQK 181
Score = 78.2 bits (184), Expect = 3e-14
Identities = 49/216 (22%), Positives = 108/216 (50%), Gaps = 7/216 (3%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDR 65
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRK 125
Query: 424 ADENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFV 582
+E R ++E ++ EER + ++ +E RL+ ++ ++ S+K
Sbjct: 126 YEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKY 185
Query: 583 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
E+E+++ D++K + + E + + ++ LE
Sbjct: 186 EEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 221
Score = 69.7 bits (163), Expect = 1e-11
Identities = 49/194 (25%), Positives = 104/194 (53%), Gaps = 7/194 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+Q A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + E
Sbjct: 43 EQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDE 102
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
E + L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ +
Sbjct: 103 EKMELQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESRCR 155
Query: 409 EAQQS---ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSR 567
E + D+N + E + Q E++ ++ LT++LKEA AE A+ ++ +
Sbjct: 156 EMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
Query: 568 KLAFVEDELEVAED 609
+ +ED+L+ ++
Sbjct: 216 TIDDLEDKLKCTKE 229
Score = 60.9 bits (141), Expect = 5e-09
Identities = 37/198 (18%), Positives = 89/198 (44%)
Frame = +1
Query: 127 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTA 306
K +QQA DA RAE++ EV ++ Q E ++ +++ ++L+ +++L
Sbjct: 13 KIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLAT 72
Query: 307 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
++ + + E ++ E R+ ++K+ + E + + + + ++ +
Sbjct: 73 ALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARK 132
Query: 487 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 666
+ + L+ AE A+ + E+ ++ ++ L+ + K + EEE+K++
Sbjct: 133 LVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKIL 192
Query: 667 GNSLKSLEVSEEKANQRV 720
+ LK E E A + V
Sbjct: 193 TDKLKEAETRAEFAERSV 210
>BC000771-1|AAH00771.1| 248|Homo sapiens tropomyosin 3 protein.
Length = 248
Score = 144 bits (350), Expect = 2e-34
Identities = 67/175 (38%), Positives = 123/175 (70%)
Frame = +1
Query: 193 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 372
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 373 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 552
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+EV+RKL +E +LE E+R + +++ E++E+++++ +LK L +EEK +Q+
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQK 181
Score = 78.2 bits (184), Expect = 3e-14
Identities = 49/216 (22%), Positives = 108/216 (50%), Gaps = 7/216 (3%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDR 65
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRK 125
Query: 424 ADENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFV 582
+E R ++E ++ EER + ++ +E RL+ ++ ++ S+K
Sbjct: 126 YEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKY 185
Query: 583 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
E+E+++ D++K + + E + + ++ LE
Sbjct: 186 EEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 221
Score = 69.7 bits (163), Expect = 1e-11
Identities = 49/194 (25%), Positives = 104/194 (53%), Gaps = 7/194 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+Q A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + E
Sbjct: 43 EQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDE 102
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
E + L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ +
Sbjct: 103 EKMELQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESRCR 155
Query: 409 EAQQS---ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSR 567
E + D+N + E + Q E++ ++ LT++LKEA AE A+ ++ +
Sbjct: 156 EMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
Query: 568 KLAFVEDELEVAED 609
+ +ED+L+ ++
Sbjct: 216 TIDDLEDKLKCTKE 229
Score = 60.9 bits (141), Expect = 5e-09
Identities = 37/198 (18%), Positives = 89/198 (44%)
Frame = +1
Query: 127 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTA 306
K +QQA DA RAE++ EV ++ Q E ++ +++ ++L+ +++L
Sbjct: 13 KIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLAT 72
Query: 307 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
++ + + E ++ E R+ ++K+ + E + + + + ++ +
Sbjct: 73 ALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARK 132
Query: 487 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 666
+ + L+ AE A+ + E+ ++ ++ L+ + K + EEE+K++
Sbjct: 133 LVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKIL 192
Query: 667 GNSLKSLEVSEEKANQRV 720
+ LK E E A + V
Sbjct: 193 TDKLKEAETRAEFAERSV 210
>AY004867-1|AAF87083.1| 247|Homo sapiens tropomyosin isoform
protein.
Length = 247
Score = 144 bits (350), Expect = 2e-34
Identities = 67/175 (38%), Positives = 123/175 (70%)
Frame = +1
Query: 193 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 372
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 373 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 552
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+EV+RKL +E +LE E+R + +++ E++E+++++ +LK L +EEK +Q+
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQK 181
Score = 78.2 bits (184), Expect = 3e-14
Identities = 49/216 (22%), Positives = 108/216 (50%), Gaps = 7/216 (3%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDR 65
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRK 125
Query: 424 ADENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFV 582
+E R ++E ++ EER + ++ +E RL+ ++ ++ S+K
Sbjct: 126 YEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKY 185
Query: 583 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
E+E+++ D++K + + E + + ++ LE
Sbjct: 186 EEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 221
Score = 69.3 bits (162), Expect = 1e-11
Identities = 51/206 (24%), Positives = 110/206 (53%), Gaps = 9/206 (4%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+Q A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + E
Sbjct: 43 EQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDE 102
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
E + L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ +
Sbjct: 103 EKMELQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESRCR 155
Query: 409 EAQQS---ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSR 567
E + D+N + E + Q E++ ++ LT++LKEA AE A+ ++ +
Sbjct: 156 EMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
Query: 568 KLAFVEDEL--EVAEDRVKSGDAKIS 639
+ +E+ L ++ +R+ S + K++
Sbjct: 216 TIDDLEERLYSQLERNRLLSNELKLT 241
Score = 60.9 bits (141), Expect = 5e-09
Identities = 37/198 (18%), Positives = 89/198 (44%)
Frame = +1
Query: 127 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTA 306
K +QQA DA RAE++ EV ++ Q E ++ +++ ++L+ +++L
Sbjct: 13 KIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLAT 72
Query: 307 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
++ + + E ++ E R+ ++K+ + E + + + + ++ +
Sbjct: 73 ALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARK 132
Query: 487 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 666
+ + L+ AE A+ + E+ ++ ++ L+ + K + EEE+K++
Sbjct: 133 LVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKIL 192
Query: 667 GNSLKSLEVSEEKANQRV 720
+ LK E E A + V
Sbjct: 193 TDKLKEAETRAEFAERSV 210
>AL590431-8|CAH71264.1| 248|Homo sapiens tropomyosin 3 protein.
Length = 248
Score = 144 bits (350), Expect = 2e-34
Identities = 67/175 (38%), Positives = 123/175 (70%)
Frame = +1
Query: 193 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 372
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 373 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 552
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+EV+RKL +E +LE E+R + +++ E++E+++++ +LK L +EEK +Q+
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQK 181
Score = 78.2 bits (184), Expect = 3e-14
Identities = 49/216 (22%), Positives = 108/216 (50%), Gaps = 7/216 (3%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDR 65
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRK 125
Query: 424 ADENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFV 582
+E R ++E ++ EER + ++ +E RL+ ++ ++ S+K
Sbjct: 126 YEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKY 185
Query: 583 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
E+E+++ D++K + + E + + ++ LE
Sbjct: 186 EEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 221
Score = 69.7 bits (163), Expect = 1e-11
Identities = 49/194 (25%), Positives = 104/194 (53%), Gaps = 7/194 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+Q A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + E
Sbjct: 43 EQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDE 102
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
E + L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ +
Sbjct: 103 EKMELQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESRCR 155
Query: 409 EAQQS---ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSR 567
E + D+N + E + Q E++ ++ LT++LKEA AE A+ ++ +
Sbjct: 156 EMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
Query: 568 KLAFVEDELEVAED 609
+ +ED+L+ ++
Sbjct: 216 TIDDLEDKLKCTKE 229
Score = 60.9 bits (141), Expect = 5e-09
Identities = 37/198 (18%), Positives = 89/198 (44%)
Frame = +1
Query: 127 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTA 306
K +QQA DA RAE++ EV ++ Q E ++ +++ ++L+ +++L
Sbjct: 13 KIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLAT 72
Query: 307 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
++ + + E ++ E R+ ++K+ + E + + + + ++ +
Sbjct: 73 ALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARK 132
Query: 487 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 666
+ + L+ AE A+ + E+ ++ ++ L+ + K + EEE+K++
Sbjct: 133 LVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKIL 192
Query: 667 GNSLKSLEVSEEKANQRV 720
+ LK E E A + V
Sbjct: 193 TDKLKEAETRAEFAERSV 210
>AL590431-7|CAH71266.1| 248|Homo sapiens tropomyosin 3 protein.
Length = 248
Score = 144 bits (350), Expect = 2e-34
Identities = 67/175 (38%), Positives = 123/175 (70%)
Frame = +1
Query: 193 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 372
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 373 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 552
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+EV+RKL +E +LE E+R + +++ E++E+++++ +LK L +EEK +Q+
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQK 181
Score = 78.2 bits (184), Expect = 3e-14
Identities = 49/216 (22%), Positives = 108/216 (50%), Gaps = 7/216 (3%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDR 65
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRK 125
Query: 424 ADENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFV 582
+E R ++E ++ EER + ++ +E RL+ ++ ++ S+K
Sbjct: 126 YEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKY 185
Query: 583 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
E+E+++ D++K + + E + + ++ LE
Sbjct: 186 EEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 221
Score = 71.7 bits (168), Expect = 2e-12
Identities = 57/220 (25%), Positives = 112/220 (50%), Gaps = 7/220 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+Q A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + E
Sbjct: 43 EQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDE 102
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
E + L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ +
Sbjct: 103 EKMELQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESRCR 155
Query: 409 EAQQS---ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSR 567
E + D+N + E + Q E++ ++ LT++LKEA AE A+ R
Sbjct: 156 EMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAE-------R 208
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSL 687
+A +E ++ ED + + K + EEL N + S+
Sbjct: 209 SVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 248
Score = 60.9 bits (141), Expect = 5e-09
Identities = 37/198 (18%), Positives = 89/198 (44%)
Frame = +1
Query: 127 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTA 306
K +QQA DA RAE++ EV ++ Q E ++ +++ ++L+ +++L
Sbjct: 13 KIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLAT 72
Query: 307 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
++ + + E ++ E R+ ++K+ + E + + + + ++ +
Sbjct: 73 ALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARK 132
Query: 487 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 666
+ + L+ AE A+ + E+ ++ ++ L+ + K + EEE+K++
Sbjct: 133 LVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKIL 192
Query: 667 GNSLKSLEVSEEKANQRV 720
+ LK E E A + V
Sbjct: 193 TDKLKEAETRAEFAERSV 210
>AF474157-1|AAL84570.1| 247|Homo sapiens TPMsk3 protein.
Length = 247
Score = 144 bits (350), Expect = 2e-34
Identities = 67/175 (38%), Positives = 123/175 (70%)
Frame = +1
Query: 193 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 372
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 373 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 552
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+EV+RKL +E +LE E+R + +++ E++E+++++ +LK L +EEK +Q+
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQK 181
Score = 78.2 bits (184), Expect = 3e-14
Identities = 49/216 (22%), Positives = 108/216 (50%), Gaps = 7/216 (3%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDR 65
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRK 125
Query: 424 ADENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFV 582
+E R ++E ++ EER + ++ +E RL+ ++ ++ S+K
Sbjct: 126 YEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKY 185
Query: 583 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
E+E+++ D++K + + E + + ++ LE
Sbjct: 186 EEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 221
Score = 70.9 bits (166), Expect = 4e-12
Identities = 57/219 (26%), Positives = 111/219 (50%), Gaps = 7/219 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+Q A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + E
Sbjct: 43 EQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDE 102
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
E + L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ +
Sbjct: 103 EKMELQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESRCR 155
Query: 409 EAQQS---ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSR 567
E + D+N + E + Q E++ ++ LT++LKEA AE A+ R
Sbjct: 156 EMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAE-------R 208
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 684
+A +E ++ ED + + K + EEL N + S
Sbjct: 209 SVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTS 247
Score = 60.9 bits (141), Expect = 5e-09
Identities = 37/198 (18%), Positives = 89/198 (44%)
Frame = +1
Query: 127 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTA 306
K +QQA DA RAE++ EV ++ Q E ++ +++ ++L+ +++L
Sbjct: 13 KIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLAT 72
Query: 307 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
++ + + E ++ E R+ ++K+ + E + + + + ++ +
Sbjct: 73 ALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARK 132
Query: 487 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 666
+ + L+ AE A+ + E+ ++ ++ L+ + K + EEE+K++
Sbjct: 133 LVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKIL 192
Query: 667 GNSLKSLEVSEEKANQRV 720
+ LK E E A + V
Sbjct: 193 TDKLKEAETRAEFAERSV 210
>X12369-1|CAA30930.1| 227|Homo sapiens tropomyosin (227 AA)
protein.
Length = 227
Score = 143 bits (347), Expect = 5e-34
Identities = 68/151 (45%), Positives = 116/151 (76%)
Frame = +1
Query: 265 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 444
+++ L E++ + TA EA+VA+LNR++Q +EE+L++++ER T QKL EA+++ADE+ R
Sbjct: 11 SSEHLHERKLRETA-EADVASLNRRIQLVEEELDRAQERLATVLQKLEEAEKAADESERG 69
Query: 445 CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 624
KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE+R +
Sbjct: 70 MKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELS 129
Query: 625 DAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+ ++ +LEE+L+++ + L+S+ +E+K +Q+
Sbjct: 130 EGQVRQLEEQLRIMDSDLESINAAEDKYSQK 160
Score = 61.7 bits (143), Expect = 3e-09
Identities = 45/179 (25%), Positives = 87/179 (48%), Gaps = 7/179 (3%)
Frame = +1
Query: 175 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 354
E +V L +++ VEE+L + +L + LEE EK +E + + + Q+ E
Sbjct: 22 ETAEADVASLNRRIQLVEEELDRAQERLATVLQKLEEAEKAADESERGMKVIESRAQKDE 81
Query: 355 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK--EARLL 528
E +E E + A+ +A + +E R ++E+ ++ EER + Q++ E +L
Sbjct: 82 EKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLR 141
Query: 529 AEDADGKS-----DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
D+D +S D+ S+K E+E++V D++K + + E + + S+ LE
Sbjct: 142 IMDSDLESINAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLE 200
Score = 59.3 bits (137), Expect = 1e-08
Identities = 46/190 (24%), Positives = 102/190 (53%), Gaps = 7/190 (3%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 26 ADVASLNRRIQLVEEELDRAQERLATVLQKLEEAEKAADESERGMKVIESRAQKDEEKME 85
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEA 414
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ Q + LE
Sbjct: 86 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGQVRQLEE 138
Query: 415 Q-QSADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAF 579
Q + D + E++ Q E+R ++ L+++LKEA AE A+ ++ + +
Sbjct: 139 QLRIMDSDLESINAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 198
Query: 580 VEDELEVAED 609
+E+++ A++
Sbjct: 199 LEEKVAHAKE 208
Score = 34.7 bits (76), Expect = 0.34
Identities = 24/104 (23%), Positives = 51/104 (49%), Gaps = 7/104 (6%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKDNAMDKADTCEQQAR--DANLRA-----EKVNEEVRELQKKLAQVE 228
+ + +K+ ++ + + A ++A+ E Q R + LR E +N + +K + E
Sbjct: 106 EEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDSDLESINAAEDKYSQKEDRYE 165
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEED 360
E++ + +KL++A E E+ +T E + L KV +E+
Sbjct: 166 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 209
>X03541-1|CAA27243.1| 641|Homo sapiens protein ( Human mRNA of trk
oncogene. ).
Length = 641
Score = 143 bits (346), Expect = 7e-34
Identities = 66/175 (37%), Positives = 123/175 (70%)
Frame = +1
Query: 193 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 372
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 373 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 552
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QL+EA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLEEAKHIAEEADRKY 126
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+EV+RKL +E +LE E+R + +++ E++E+++++ +LK L +EEK +Q+
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQK 181
Score = 80.2 bits (189), Expect = 7e-15
Identities = 51/227 (22%), Positives = 112/227 (49%), Gaps = 7/227 (3%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDR 65
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLEEAKHIAEEADRK 125
Query: 424 ADENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFV 582
+E R ++E ++ EER + ++ +E RL+ ++ ++ S+K
Sbjct: 126 YEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKY 185
Query: 583 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
E+E+++ D++K + + E + + ++ LE + + VE
Sbjct: 186 EEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPVE 232
Score = 71.3 bits (167), Expect = 3e-12
Identities = 52/200 (26%), Positives = 104/200 (52%), Gaps = 7/200 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+Q A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + E
Sbjct: 43 EQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDE 102
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
E + L + +LE+A EE +++ EVA RK+ IE DLE++EER+ A+ +
Sbjct: 103 EKMELQEIQLEEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESRCR 155
Query: 409 EAQQS---ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSR 567
E + D+N + E + Q E++ ++ LT++LKEA AE A+ ++ +
Sbjct: 156 EMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
Query: 568 KLAFVEDELEVAEDRVKSGD 627
+ +ED + D V+ D
Sbjct: 216 TIDDLEDTNSTSGDPVEKKD 235
>DQ120714-1|ABC40673.1| 247|Homo sapiens rcTPM3 protein.
Length = 247
Score = 139 bits (336), Expect = 1e-32
Identities = 66/175 (37%), Positives = 121/175 (69%)
Frame = +1
Query: 193 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 372
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L++
Sbjct: 6 IEAVKRKIQVLQQQADDAEERAERLQQEVEGERRARKQAEAEVASLNRRIQLVEEELDRP 65
Query: 373 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 552
+ER TA QKL EA+++A E+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 66 QERLATALQKLEEAEKAAGESERGMKVIENRALKDEEKMELQELQLKEAKHIAEEADRKY 125
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+EV+RKL +E +LE E+R + +++ E++E+++++ +LK L +EEK +Q+
Sbjct: 126 EEVARKLVTIEGDLERTEERAELTESRCREMDEQIRLMDQNLKCLSAAEEKYSQK 180
Score = 72.9 bits (171), Expect = 1e-12
Identities = 49/216 (22%), Positives = 105/216 (48%), Gaps = 7/216 (3%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T++A+K+K+Q ++ + D+A ++A+ +Q+ ++ EV L +++ VEE+L
Sbjct: 5 TIEAVKRKIQVLQQQADDAEERAERLQQEVEGERRARKQAEAEVASLNRRIQLVEEELDR 64
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 65 PQERLATALQKLEEAEKAAGESERGMKVIENRALKDEEKMELQELQLKEAKHIAEEADRK 124
Query: 424 ADENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFV 582
+E R +E ++ EER + ++ +E RL+ ++ ++ S+K
Sbjct: 125 YEEVARKLVTIEGDLERTEERAELTESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKY 184
Query: 583 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
E+E+++ D+ K + E + + ++ LE
Sbjct: 185 EEEIKIFTDKPKEAETCAEFAERSVAKLEKTIDDLE 220
Score = 60.9 bits (141), Expect = 5e-09
Identities = 45/194 (23%), Positives = 99/194 (51%), Gaps = 7/194 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+Q A + ++ +++Q ++ E D ++ T Q+ +A A + ++ ++ + + E
Sbjct: 42 KQAEAEVASLNRRIQLVEEELDRPQERLATALQKLEEAEKAAGESERGMKVIENRALKDE 101
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
E + L + +L++A EE +++ EVA RK+ IE DLE++EER+ + +
Sbjct: 102 EKMELQELQLKEAKHIAEEADRKYE----EVA---RKLVTIEGDLERTEERAELTESRCR 154
Query: 409 EAQQS---ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSR 567
E + D+N + E + Q E++ ++ T++ KEA AE A+ ++ +
Sbjct: 155 EMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKIFTDKPKEAETCAEFAERSVAKLEK 214
Query: 568 KLAFVEDELEVAED 609
+ +ED+L+ ++
Sbjct: 215 TIDDLEDKLKCTKE 228
Score = 56.8 bits (131), Expect = 7e-08
Identities = 35/198 (17%), Positives = 87/198 (43%)
Frame = +1
Query: 127 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTA 306
K +QQA DA RAE++ +EV ++ Q E ++ +++ ++L+ +++L
Sbjct: 12 KIQVLQQQADDAEERAERLQQEVEGERRARKQAEAEVASLNRRIQLVEEELDRPQERLAT 71
Query: 307 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
++ + + E ++ E R+ ++K+ + E + + + + ++ +
Sbjct: 72 ALQKLEEAEKAAGESERGMKVIENRALKDEEKMELQELQLKEAKHIAEEADRKYEEVARK 131
Query: 487 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 666
+ + L+ AE + + E+ ++ ++ L+ + K + EEE+K+
Sbjct: 132 LVTIEGDLERTEERAELTESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKIF 191
Query: 667 GNSLKSLEVSEEKANQRV 720
+ K E E A + V
Sbjct: 192 TDKPKEAETCAEFAERSV 209
>AK129882-1|BAC85248.1| 217|Homo sapiens protein ( Homo sapiens
cDNA FLJ26372 fis, clone HRT06233. ).
Length = 217
Score = 134 bits (324), Expect = 3e-31
Identities = 78/217 (35%), Positives = 126/217 (58%), Gaps = 5/217 (2%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
MDAIKKKMQ +KL+K+NA+D+A+ E + A R++++ +E+ LQKKL E++L
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
L+ A + LE EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+ S
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAELS- 119
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
E + + EE + +TN LK AE K D ++ + D+L+ AE
Sbjct: 120 ----------EGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAE 169
Query: 607 DRVKSGDAKISELEEEL-----KVVGNSLKSLEVSEE 702
R + + +++LE+ + ++ LK +SEE
Sbjct: 170 TRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEE 206
Score = 74.1 bits (174), Expect = 5e-13
Identities = 51/176 (28%), Positives = 87/176 (49%), Gaps = 3/176 (1%)
Frame = +1
Query: 202 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 381
++KK+ ++ D ++ EQA D + E + E E+ +L +K++ E++L+K E
Sbjct: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
Query: 382 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD---GKS 552
AQ+KL A++ A + L R Q EE +D+ +L A E+A+ GK
Sbjct: 64 LKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAELSEGKC 123
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
E+ +L V + L+ E + + K EEE+KV+ + LK E E A + V
Sbjct: 124 AELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSV 179
Score = 62.9 bits (146), Expect = 1e-09
Identities = 44/148 (29%), Positives = 81/148 (54%), Gaps = 17/148 (11%)
Frame = +1
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
A+ +K+Q ++ D E + +R+ A+ A+ + + L+ + + E+ +D+ +
Sbjct: 3 AIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSE 62
Query: 505 QLKEARL---LAE----DADGKSDEVSRKLAFVEDELEVAEDRVKSG----------DAK 633
LK+A+ LAE DA+ ++R++ VE+EL+ A++R+ + + K
Sbjct: 63 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAELSEGK 122
Query: 634 ISELEEELKVVGNSLKSLEVSEEKANQR 717
+ELEEELK V N+LKSLE EK +Q+
Sbjct: 123 CAELEEELKTVTNNLKSLEAQAEKYSQK 150
>AL590431-5|CAH71263.1| 224|Homo sapiens tropomyosin 3 protein.
Length = 224
Score = 115 bits (276), Expect = 2e-25
Identities = 59/141 (41%), Positives = 96/141 (68%)
Frame = +1
Query: 295 QLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQ 474
Q A +AE A R +++E + E+R TA QKL EA+++ADE+ R KV+ENRA +
Sbjct: 18 QQQADDAEERA-ERLQREVEGERRAREQRLATALQKLEEAEKAADESERGMKVIENRALK 76
Query: 475 DEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 654
DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E +LE E+R + +++ E++E+
Sbjct: 77 DEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQ 136
Query: 655 LKVVGNSLKSLEVSEEKANQR 717
++++ +LK L +EEK +Q+
Sbjct: 137 IRLMDQNLKCLSAAEEKYSQK 157
Score = 68.9 bits (161), Expect = 2e-11
Identities = 48/200 (24%), Positives = 105/200 (52%), Gaps = 18/200 (9%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTC------EQQARDANL-----RAEKVNEEVRELQK 210
T++A+K+K+Q ++ + D+A ++A+ E++AR+ L + E+ + E ++
Sbjct: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQRLATALQKLEEAEKAADESER 65
Query: 211 KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 390
+ +E + ++ K+E L+E + + + + RK+ IE DLE++EER+
Sbjct: 66 GMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAEL 125
Query: 391 AQQKLLEAQQS---ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGK 549
A+ + E + D+N + E + Q E++ ++ LT++LKEA AE A+
Sbjct: 126 AESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERS 185
Query: 550 SDEVSRKLAFVEDELEVAED 609
++ + + +ED+L+ ++
Sbjct: 186 VAKLEKTIDDLEDKLKCTKE 205
>AL590431-6|CAH71265.1| 232|Homo sapiens tropomyosin 3 protein.
Length = 232
Score = 109 bits (262), Expect = 1e-23
Identities = 57/175 (32%), Positives = 111/175 (63%)
Frame = +1
Query: 193 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 372
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 373 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 552
+ER TA QKL EA+++ADE ++M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADE----------------KKMELQEIQLKEAKHIAEEADRKY 110
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+EV+RKL +E +LE E+R + +++ E++E+++++ +LK L +EEK +Q+
Sbjct: 111 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQK 165
Score = 81.4 bits (192), Expect = 3e-15
Identities = 48/219 (21%), Positives = 112/219 (51%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDR 65
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
+ +L A + LEE EK A E ++ ++++ + E+++ + +KL+ +
Sbjct: 66 AQERLATALQKLEEAEK--AADEKKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGD 123
Query: 424 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 603
+ ++ E+R ++ +E++ + LK E K D+ ++ + D+L+ A
Sbjct: 124 LERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEA 183
Query: 604 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
E R + + +++LE+ + + + LK + E QR+
Sbjct: 184 ETRAEFAERSVAKLEKTIDDLEDKLKCTK-EEHLCTQRM 221
>BC062740-1|AAH62740.1| 158|Homo sapiens TPM3 protein protein.
Length = 158
Score = 97.5 bits (232), Expect = 4e-20
Identities = 49/90 (54%), Positives = 67/90 (74%)
Frame = +1
Query: 448 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 627
KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E +LE E+R + +
Sbjct: 2 KVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAE 61
Query: 628 AKISELEEELKVVGNSLKSLEVSEEKANQR 717
+K SELEEELK V N+LKSLE EK +Q+
Sbjct: 62 SKCSELEEELKNVTNNLKSLEAQAEKYSQK 91
Score = 58.8 bits (136), Expect = 2e-08
Identities = 36/155 (23%), Positives = 76/155 (49%)
Frame = +1
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 402
+E + ++ K+E L+E + + + + RK+ IE DLE++EER+ A+ K
Sbjct: 4 IENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESK 63
Query: 403 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 582
E ++ K LE +A++ ++ D+ ++K ++A+ +++ R +A +
Sbjct: 64 CSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKL 123
Query: 583 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSL 687
E ++ ED + + K + EEL N + S+
Sbjct: 124 EKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 158
>AL590431-4|CAH71262.1| 158|Homo sapiens tropomyosin 3 protein.
Length = 158
Score = 97.5 bits (232), Expect = 4e-20
Identities = 49/90 (54%), Positives = 67/90 (74%)
Frame = +1
Query: 448 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 627
KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E +LE E+R + +
Sbjct: 2 KVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAE 61
Query: 628 AKISELEEELKVVGNSLKSLEVSEEKANQR 717
+K SELEEELK V N+LKSLE EK +Q+
Sbjct: 62 SKCSELEEELKNVTNNLKSLEAQAEKYSQK 91
Score = 58.8 bits (136), Expect = 2e-08
Identities = 36/155 (23%), Positives = 76/155 (49%)
Frame = +1
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 402
+E + ++ K+E L+E + + + + RK+ IE DLE++EER+ A+ K
Sbjct: 4 IENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESK 63
Query: 403 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 582
E ++ K LE +A++ ++ D+ ++K ++A+ +++ R +A +
Sbjct: 64 CSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKL 123
Query: 583 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSL 687
E ++ ED + + K + EEL N + S+
Sbjct: 124 EKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 158
>AL590431-3|CAH71261.1| 158|Homo sapiens tropomyosin 3 protein.
Length = 158
Score = 97.5 bits (232), Expect = 4e-20
Identities = 49/90 (54%), Positives = 67/90 (74%)
Frame = +1
Query: 448 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 627
KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E +LE E+R + +
Sbjct: 2 KVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAE 61
Query: 628 AKISELEEELKVVGNSLKSLEVSEEKANQR 717
+K SELEEELK V N+LKSLE EK +Q+
Sbjct: 62 SKCSELEEELKNVTNNLKSLEAQAEKYSQK 91
Score = 54.0 bits (124), Expect = 5e-07
Identities = 31/132 (23%), Positives = 68/132 (51%)
Frame = +1
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 402
+E + ++ K+E L+E + + + + RK+ IE DLE++EER+ A+ K
Sbjct: 4 IENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESK 63
Query: 403 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 582
E ++ K LE +A++ ++ D+ ++K ++A+ +++ R +A +
Sbjct: 64 CSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKL 123
Query: 583 EDELEVAEDRVK 618
E ++ ED++K
Sbjct: 124 EKTIDDLEDKLK 135
Score = 35.5 bits (78), Expect = 0.19
Identities = 37/143 (25%), Positives = 65/143 (45%), Gaps = 1/143 (0%)
Frame = +1
Query: 184 NEEVRELQK-KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEED 360
+EE ELQ+ +L + + K E+ + L E L TE K ++EE+
Sbjct: 11 DEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEE 70
Query: 361 LEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA 540
L ++ T K LEAQ + + + EE + LT++LKEA AE A
Sbjct: 71 L-----KNVTNNLKSLEAQ---------AEKYSQKEDKYEEEIKILTDKLKEAETRAEFA 116
Query: 541 DGKSDEVSRKLAFVEDELEVAED 609
+ ++ + + +ED+L+ ++
Sbjct: 117 ERSVAKLEKTIDDLEDKLKCTKE 139
>AF186110-1|AAG17015.1| 227|Homo sapiens TPM4-ALK fusion
oncoprotein type 1 protein.
Length = 227
Score = 96.3 bits (229), Expect = 1e-19
Identities = 48/90 (53%), Positives = 67/90 (74%)
Frame = +1
Query: 448 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 627
KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E ELE AE+R + +
Sbjct: 2 KVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSE 61
Query: 628 AKISELEEELKVVGNSLKSLEVSEEKANQR 717
K +LEEELK V N+LKSLE + EK +++
Sbjct: 62 LKCGDLEEELKNVTNNLKSLEAASEKYSEK 91
Score = 39.5 bits (88), Expect = 0.012
Identities = 29/133 (21%), Positives = 58/133 (43%), Gaps = 7/133 (5%)
Frame = +1
Query: 328 LNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD----- 492
+ + + EE +E E + A+ EA + +E R +LE ++ EER +
Sbjct: 4 IENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELK 63
Query: 493 --QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 666
L +LK + + S++ S K E+E+++ D++K + + E + +
Sbjct: 64 CGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKL 123
Query: 667 GNSLKSLEVSEEK 705
++ LEV K
Sbjct: 124 EKTIDDLEVYRRK 136
>AK092712-1|BAC03956.1| 183|Homo sapiens protein ( Homo sapiens
cDNA FLJ35393 fis, clone SKNSH2000971, highly similar to
TROPOMYOSIN, CYTOSKELETAL TYPE. ).
Length = 183
Score = 75.8 bits (178), Expect = 1e-13
Identities = 35/108 (32%), Positives = 70/108 (64%)
Frame = +1
Query: 394 QQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 573
++K+ QQ AD+ + L+ + ++ + ++ QLKEA+ +AE+AD K +EV+RKL
Sbjct: 11 KRKIQVLQQQADDAEERAERLQREVEGEKMELQEI--QLKEAKHIAEEADRKYEEVARKL 68
Query: 574 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+E +LE E+R + +++ E++E+++++ +LK L +EEK +Q+
Sbjct: 69 VIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQK 116
Score = 57.6 bits (133), Expect = 4e-08
Identities = 48/168 (28%), Positives = 87/168 (51%), Gaps = 7/168 (4%)
Frame = +1
Query: 127 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTA 306
K +QQA DA RAE++ EV + +L +++ L++A EE +++
Sbjct: 13 KIQVLQQQADDAEERAERLQREVEGEKMELQEIQ---------LKEAKHIAEEADRKYE- 62
Query: 307 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS---ADENNRMCKVLENRAQQD 477
EVA RK+ IE DLE++EER+ A+ + E + D+N + E + Q
Sbjct: 63 ---EVA---RKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQK 116
Query: 478 EERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 609
E++ ++ LT++LKEA AE A+ ++ + + +ED+L+ ++
Sbjct: 117 EDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKE 164
>BX537964-1|CAD97928.1| 898|Homo sapiens hypothetical protein
protein.
Length = 898
Score = 69.3 bits (162), Expect = 1e-11
Identities = 57/224 (25%), Positives = 99/224 (44%), Gaps = 5/224 (2%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++ A M+ KK + + EK+ + K E+++ D LR EK L+KKL
Sbjct: 288 KEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLD--LRKEK-----ETLEKKLRDAN 340
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
++L N NK++Q +++ + E E L R++ +++ED+ + AQ KL
Sbjct: 341 KELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLK 400
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKE-ARLLAEDADGKSDEVSRKLAFVE 585
S E K + Q +E DQ+ ++ + E + KS+E+ KL +
Sbjct: 401 AEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTK 460
Query: 586 DELE----VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
ELE D+++ AKI ELE+ + + L K
Sbjct: 461 GELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTK 504
Score = 42.3 bits (95), Expect = 0.002
Identities = 42/227 (18%), Positives = 97/227 (42%), Gaps = 15/227 (6%)
Frame = +1
Query: 85 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 264
K++ + EK +T E + +K+ E++ K+ + L + ++
Sbjct: 349 KIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKE 408
Query: 265 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE------------RSGTAQQKLL 408
L+E +LT + E + + Q + + ++SEE G ++++
Sbjct: 409 TKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQ 468
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-- 582
E + ++ K LE+ + +E MD+L + + L ++ DE+S+ +
Sbjct: 469 EKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINR 528
Query: 583 -EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ E++ D+VK+ D +L+E+L+ +++L+ E N +
Sbjct: 529 QKAEIQNLLDKVKTAD----QLQEQLQRGKQEIENLKEEVESLNSLI 571
>BC105632-1|AAI05633.1| 898|Homo sapiens chromosome 10 open reading
frame 118 protein.
Length = 898
Score = 69.3 bits (162), Expect = 1e-11
Identities = 57/224 (25%), Positives = 99/224 (44%), Gaps = 5/224 (2%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++ A M+ KK + + EK+ + K E+++ D LR EK L+KKL
Sbjct: 288 KEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLD--LRKEK-----ETLEKKLRDAN 340
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
++L N NK++Q +++ + E E L R++ +++ED+ + AQ KL
Sbjct: 341 KELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLK 400
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKE-ARLLAEDADGKSDEVSRKLAFVE 585
S E K + Q +E DQ+ ++ + E + KS+E+ KL +
Sbjct: 401 AEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTK 460
Query: 586 DELE----VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
ELE D+++ AKI ELE+ + + L K
Sbjct: 461 GELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTK 504
Score = 42.3 bits (95), Expect = 0.002
Identities = 42/227 (18%), Positives = 97/227 (42%), Gaps = 15/227 (6%)
Frame = +1
Query: 85 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 264
K++ + EK +T E + +K+ E++ K+ + L + ++
Sbjct: 349 KIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKE 408
Query: 265 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE------------RSGTAQQKLL 408
L+E +LT + E + + Q + + ++SEE G ++++
Sbjct: 409 TKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQ 468
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-- 582
E + ++ K LE+ + +E MD+L + + L ++ DE+S+ +
Sbjct: 469 EKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINR 528
Query: 583 -EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ E++ D+VK+ D +L+E+L+ +++L+ E N +
Sbjct: 529 QKAEIQNLLDKVKTAD----QLQEQLQRGKQEIENLKEEVESLNSLI 571
>BC103499-1|AAI03500.1| 898|Homo sapiens chromosome 10 open reading
frame 118 protein.
Length = 898
Score = 69.3 bits (162), Expect = 1e-11
Identities = 57/224 (25%), Positives = 99/224 (44%), Gaps = 5/224 (2%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++ A M+ KK + + EK+ + K E+++ D LR EK L+KKL
Sbjct: 288 KEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLD--LRKEK-----ETLEKKLRDAN 340
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
++L N NK++Q +++ + E E L R++ +++ED+ + AQ KL
Sbjct: 341 KELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLK 400
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKE-ARLLAEDADGKSDEVSRKLAFVE 585
S E K + Q +E DQ+ ++ + E + KS+E+ KL +
Sbjct: 401 AEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTK 460
Query: 586 DELE----VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
ELE D+++ AKI ELE+ + + L K
Sbjct: 461 GELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTK 504
Score = 42.3 bits (95), Expect = 0.002
Identities = 42/227 (18%), Positives = 97/227 (42%), Gaps = 15/227 (6%)
Frame = +1
Query: 85 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 264
K++ + EK +T E + +K+ E++ K+ + L + ++
Sbjct: 349 KIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKE 408
Query: 265 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE------------RSGTAQQKLL 408
L+E +LT + E + + Q + + ++SEE G ++++
Sbjct: 409 TKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQ 468
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-- 582
E + ++ K LE+ + +E MD+L + + L ++ DE+S+ +
Sbjct: 469 EKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINR 528
Query: 583 -EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ E++ D+VK+ D +L+E+L+ +++L+ E N +
Sbjct: 529 QKAEIQNLLDKVKTAD----QLQEQLQRGKQEIENLKEEVESLNSLI 571
>BC100670-1|AAI00671.1| 1004|Homo sapiens C10orf118 protein protein.
Length = 1004
Score = 69.3 bits (162), Expect = 1e-11
Identities = 57/224 (25%), Positives = 99/224 (44%), Gaps = 5/224 (2%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++ A M+ KK + + EK+ + K E+++ D LR EK L+KKL
Sbjct: 394 KEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLD--LRKEK-----ETLEKKLRDAN 446
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
++L N NK++Q +++ + E E L R++ +++ED+ + AQ KL
Sbjct: 447 KELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLK 506
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKE-ARLLAEDADGKSDEVSRKLAFVE 585
S E K + Q +E DQ+ ++ + E + KS+E+ KL +
Sbjct: 507 AEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTK 566
Query: 586 DELE----VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
ELE D+++ AKI ELE+ + + L K
Sbjct: 567 GELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTK 610
Score = 42.3 bits (95), Expect = 0.002
Identities = 42/227 (18%), Positives = 97/227 (42%), Gaps = 15/227 (6%)
Frame = +1
Query: 85 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 264
K++ + EK +T E + +K+ E++ K+ + L + ++
Sbjct: 455 KIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKE 514
Query: 265 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE------------RSGTAQQKLL 408
L+E +LT + E + + Q + + ++SEE G ++++
Sbjct: 515 TKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQ 574
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-- 582
E + ++ K LE+ + +E MD+L + + L ++ DE+S+ +
Sbjct: 575 EKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINR 634
Query: 583 -EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ E++ D+VK+ D +L+E+L+ +++L+ E N +
Sbjct: 635 QKAEIQNLLDKVKTAD----QLQEQLQRGKQEIENLKEEVESLNSLI 677
>AF273054-1|AAM44457.1| 613|Homo sapiens CTCL tumor antigen
HD-CL-01 protein.
Length = 613
Score = 69.3 bits (162), Expect = 1e-11
Identities = 57/224 (25%), Positives = 99/224 (44%), Gaps = 5/224 (2%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++ A M+ KK + + EK+ + K E+++ D LR EK L+KKL
Sbjct: 105 KEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLD--LRKEK-----ETLEKKLRDAN 157
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
++L N NK++Q +++ + E E L R++ +++ED+ + AQ KL
Sbjct: 158 KELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLK 217
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKE-ARLLAEDADGKSDEVSRKLAFVE 585
S E K + Q +E DQ+ ++ + E + KS+E+ KL +
Sbjct: 218 AEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTK 277
Query: 586 DELE----VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
ELE D+++ AKI ELE+ + + L K
Sbjct: 278 GELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTK 321
Score = 42.3 bits (95), Expect = 0.002
Identities = 42/227 (18%), Positives = 97/227 (42%), Gaps = 15/227 (6%)
Frame = +1
Query: 85 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 264
K++ + EK +T E + +K+ E++ K+ + L + ++
Sbjct: 166 KIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKE 225
Query: 265 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE------------RSGTAQQKLL 408
L+E +LT + E + + Q + + ++SEE G ++++
Sbjct: 226 TKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQ 285
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-- 582
E + ++ K LE+ + +E MD+L + + L ++ DE+S+ +
Sbjct: 286 EKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINR 345
Query: 583 -EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ E++ D+VK+ D +L+E+L+ +++L+ E N +
Sbjct: 346 QKAEIQNLLDKVKTAD----QLQEQLQRGKQEIENLKEEVESLNSLI 388
>M12127-1|AAA36774.1| 131|Homo sapiens protein ( Human cytoskeletal
tropomyosin isoform (3.0 kb) mRNA, 3' end. ).
Length = 131
Score = 68.5 bits (160), Expect = 2e-11
Identities = 32/64 (50%), Positives = 48/64 (75%)
Frame = +1
Query: 526 LAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+AE+AD K +EV+RKL +E ELE AE+R + ++K +LEEEL+ V N+LKSLE + EK
Sbjct: 1 IAEEADRKYEEVARKLVILEGELERAEERAEVSESKCGDLEEELRTVTNNLKSLEAASEK 60
Query: 706 ANQR 717
+++
Sbjct: 61 YSEK 64
>M12126-1|AAA61229.1| 131|Homo sapiens TPM2 protein.
Length = 131
Score = 66.9 bits (156), Expect = 7e-11
Identities = 31/60 (51%), Positives = 45/60 (75%)
Frame = +1
Query: 526 LAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+AED+D K +EV+RKL +E ELE +E+R + ++K +LEEELK+V N+LKSLE +K
Sbjct: 1 IAEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADK 60
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/125 (31%), Positives = 61/125 (48%), Gaps = 7/125 (5%)
Frame = +1
Query: 334 RKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRA-----QQD--EERMD 492
RK+ +E +LE+SEER+ A+ K + ++ K LE +A ++D EE +
Sbjct: 14 RKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIK 73
Query: 493 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 672
L +LKEA AE A+ R +A +E ++ ED V + K + EEL N
Sbjct: 74 LLEEKLKEAETRAEFAE-------RSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALN 126
Query: 673 SLKSL 687
+ SL
Sbjct: 127 DITSL 131
Score = 36.7 bits (81), Expect = 0.084
Identities = 25/123 (20%), Positives = 60/123 (48%)
Frame = +1
Query: 151 ARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL 330
A D++ + E+V ++ L+ +L + EE + ++K ++L+ L + EA+
Sbjct: 2 AEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKY 61
Query: 331 NRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL 510
+ K + EE+++ EE+ A+ + A++S + + LE+ + + ++ +L
Sbjct: 62 STKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEEL 121
Query: 511 KEA 519
A
Sbjct: 122 DNA 124
>S73840-1|AAC13916.1| 231|Homo sapiens type IIA myosin heavy chain
protein.
Length = 231
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/214 (22%), Positives = 109/214 (50%), Gaps = 5/214 (2%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T ++ + M+ E ++ + +A E++A+ A A + EE+++ Q A +E +
Sbjct: 22 TKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 78
Query: 244 NKNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
KN +EQ KDL E ++ L + ++ L +V+++E ++E ++R+ A + L
Sbjct: 79 KKN-MEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLR 137
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
+ ++ E + + ++ +D+L ++K + AE+A+ +S+ K ++
Sbjct: 138 KHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQH 197
Query: 589 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
ELE AE+R ++++++L + + V + S E
Sbjct: 198 ELEEAEERADIAESQVNKLRVKSREVHTKVISEE 231
Score = 43.2 bits (97), Expect = 0.001
Identities = 30/184 (16%), Positives = 86/184 (46%), Gaps = 1/184 (0%)
Frame = +1
Query: 175 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 354
+K+ ++ ++Q ++ + ++ + K ++A D ++L + A L R + +E
Sbjct: 24 KKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 83
Query: 355 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 531
+ ++ + R A+Q L+ ++ + + LE + +++R + L++
Sbjct: 84 QTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRV 143
Query: 532 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
++ +++E + + ++D ++ + +VKS + E EE+ + L+ E+A
Sbjct: 144 KELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAE 203
Query: 712 QRVE 723
+R +
Sbjct: 204 ERAD 207
>BC129821-1|AAI29822.1| 315|Homo sapiens FLJ36144 protein protein.
Length = 315
Score = 62.9 bits (146), Expect = 1e-09
Identities = 41/174 (23%), Positives = 94/174 (54%), Gaps = 1/174 (0%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
E++ R+ + + E++ +K+L + E++L + +L + K+L E+E+Q+ E ++
Sbjct: 26 EERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELRE-QKELREQEEQMQEQEEKM 84
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS-ADENNRMCKVLENRAQQDEERMDQL 498
K+++ EE + + EER ++++ E +Q D+ RM + + R ++ EERM +
Sbjct: 85 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWE-QDERLREKEERMREQ 143
Query: 499 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 660
++ + E+ K E +K E++++ E+R++ + K+ E EE ++
Sbjct: 144 EKMWEQVEKMREEK--KMQEQEKKTRDQEEKMQ-EEERIREREKKMREEEETMR 194
Score = 48.0 bits (109), Expect = 3e-05
Identities = 42/197 (21%), Positives = 94/197 (47%), Gaps = 4/197 (2%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKV----NEEVRELQKKLAQVEEDLILN 246
K + Q K+ + + E + ++ LR +K E+++E ++K+ + EE +
Sbjct: 35 KMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQ 94
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+ K+ + + L E+EKQ+ E ++ ++ + +E L + EER Q+K+ E +
Sbjct: 95 EEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM-REQEKMWEQVEKM 153
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
E +M + E + + EE+M Q +++E + + E K+ E+ + E
Sbjct: 154 REEKKM-QEQEKKTRDQEEKM-QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 211
Query: 607 DRVKSGDAKISELEEEL 657
++ + ++ E +E+L
Sbjct: 212 EK-EWQQQRLPEQKEKL 227
Score = 46.8 bits (106), Expect = 8e-05
Identities = 40/179 (22%), Positives = 91/179 (50%), Gaps = 1/179 (0%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL-QKKLAQVEEDLILNKN 252
++++ Q M+ +++ M + D ++ + EK+ E+V ++ ++K Q +E ++
Sbjct: 112 MREQEQKMR-DQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQE 170
Query: 253 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 432
+ Q + + E+EK++ E + K+Q+ EE++ + EE+ QQ+L E ++ E
Sbjct: 171 EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE-WQQQRLPEQKEKLWE 229
Query: 433 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 609
+M + E +Q+E+ DQ +E ++ ++ + ++V A +D E ED
Sbjct: 230 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDVG---AGGDDAREGGED 285
Score = 43.2 bits (97), Expect = 0.001
Identities = 32/166 (19%), Positives = 80/166 (48%), Gaps = 2/166 (1%)
Frame = +1
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
EE+L + K+ + + + +E++L E ++ K+ + E+ L + +E+ Q+K
Sbjct: 5 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRL-REQEKELREQEKE 63
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL--KEARLLAEDADGKSDEVSRKLAF 579
L Q+ E + E + + EE+M + ++ +E RL ++ + E +K+
Sbjct: 64 LREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE--QKMRD 121
Query: 580 VEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
E+ + ++R++ + ++ E E+ + V + ++ E++ R
Sbjct: 122 QEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTR 167
Score = 41.9 bits (94), Expect = 0.002
Identities = 34/158 (21%), Positives = 76/158 (48%), Gaps = 7/158 (4%)
Frame = +1
Query: 271 KDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN---R 441
++L E+EK++ E ++ ++++ E + + EE+ +++L E ++ E R
Sbjct: 6 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELR 65
Query: 442 MCKVL---ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 612
K L E + Q+ EE+M + +++E + + E +++ E ++ E+R
Sbjct: 66 EQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 125
Query: 613 VKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVE 723
+ D ++ E EE ++ + +E + EEK Q E
Sbjct: 126 MWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQE 163
>BC126409-1|AAI26410.1| 1941|Homo sapiens myosin, heavy chain 2,
skeletal muscle, adult protein.
Length = 1941
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/214 (22%), Positives = 109/214 (50%), Gaps = 5/214 (2%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T ++ + M+ E ++ + +A E++A+ A A + EE+++ Q A +E +
Sbjct: 1732 TKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 1788
Query: 244 NKNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
KN +EQ KDL E ++ L + ++ L +V+++E ++E ++R+ A + L
Sbjct: 1789 KKN-MEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLR 1847
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
+ ++ E + + ++ +D+L ++K + AE+A+ +S+ K ++
Sbjct: 1848 KHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQH 1907
Query: 589 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
ELE AE+R ++++++L + + V + S E
Sbjct: 1908 ELEEAEERADIAESQVNKLRVKSREVHTKVISEE 1941
Score = 58.0 bits (134), Expect = 3e-08
Identities = 49/222 (22%), Positives = 109/222 (49%), Gaps = 9/222 (4%)
Frame = +1
Query: 76 IKKKMQA---MKLEKDNAMDKAD-TCEQQARDANLRAE--KVNEEVRELQKKLAQVEEDL 237
IK K+Q +K + A D+ + E A+ L E ++ +++ +L+ LA+VE++
Sbjct: 915 IKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 974
Query: 238 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 417
+NK++ +++ ++ + E AL QQ +DL+ E++ T + ++ +
Sbjct: 975 HATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLE 1034
Query: 418 QSADENNRMCKVLENRAQQDEERMD-QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 594
Q D+ + E + + D ER +L LK A+ D + + ++ KL E E+
Sbjct: 1035 QQVDDLEGSLE-QEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEI 1093
Query: 595 EVAEDRVKSGDAKISELEEELKVVGNSLKSL--EVSEEKANQ 714
+ +++ A +L++++K + ++ L E+ E+A++
Sbjct: 1094 SNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASR 1135
Score = 48.4 bits (110), Expect = 3e-05
Identities = 35/141 (24%), Positives = 69/141 (48%), Gaps = 7/141 (4%)
Frame = +1
Query: 307 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
TE E+A + + Q+I+++L KSE + ++K++ + ++ + EER
Sbjct: 851 TEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEER 910
Query: 487 MDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
DQL ++KE AED + + E++ K +EDE + + + ++++
Sbjct: 911 CDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 970
Query: 646 EEELKVVGNSLKSLEVSEEKA 708
E+E N +K+L +EE A
Sbjct: 971 EKEKHATENKVKNL--TEEMA 989
Score = 46.8 bits (106), Expect = 8e-05
Identities = 35/226 (15%), Positives = 102/226 (45%), Gaps = 1/226 (0%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++ AT++ ++ + + E +A ++ Q +K+ ++ ++Q ++ +
Sbjct: 1692 EELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDIL 1751
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
++ + K ++A D ++L + A L R + +E+ ++ + R A+Q L
Sbjct: 1752 QEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLAL 1811
Query: 409 EA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
+ ++ + + LE + +++R + L++ ++ +++E + + ++
Sbjct: 1812 KGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQ 1871
Query: 586 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
D ++ + +VKS + E EE+ + L+ E+A +R +
Sbjct: 1872 DLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERAD 1917
Score = 37.9 bits (84), Expect = 0.036
Identities = 44/218 (20%), Positives = 90/218 (41%), Gaps = 10/218 (4%)
Frame = +1
Query: 100 KLEKDNAMDKADTCEQQA--RDANLRAEKVNEEVRELQKKLAQVEEDL---ILNKN-KLE 261
+LEK + + CE QA +A E ++ +Q +L QV+ ++ I K+ +++
Sbjct: 1531 ELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEID 1590
Query: 262 QANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 429
Q ++ + E + +AE+ + N R +++E DL + E + A + EA ++
Sbjct: 1591 QLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYR 1650
Query: 430 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 609
+ K + + L QL A + +E+ L E ++AE
Sbjct: 1651 NTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQ 1710
Query: 610 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ ++ L + + N+ K LE + +E
Sbjct: 1711 ELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEME 1748
Score = 36.3 bits (80), Expect = 0.11
Identities = 47/217 (21%), Positives = 104/217 (47%), Gaps = 1/217 (0%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
MD +K Q + K + ++ + + D ++ ++++ELQ ++ ++EE++
Sbjct: 1073 MDIENEKQQLDEKLKKKEFEISNL-QSKIEDEQALGIQLQKKIKELQARIEELEEEI--- 1128
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+ E+A++ EK++ + L+R++++I E LE E T+ Q + ++ A
Sbjct: 1129 --EAERASRAKAEKQR---------SDLSRELEEISERLE--EAGGATSAQIEMNKKREA 1175
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEA-RLLAEDADGKSDEVSRKLAFVEDELEVA 603
E +M + LE Q E L + ++ L E D V +KL + E+++
Sbjct: 1176 -EFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQID-NLQRVKQKLEKEKSEMKME 1233
Query: 604 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
D + S +S+ + L+ + +L+ ++SE K+ +
Sbjct: 1234 IDDLASNVETVSKAKGNLEKMCRTLED-QLSELKSKE 1269
>AF111784-1|AAD29950.1| 1941|Homo sapiens myosin heavy chain IIa
protein.
Length = 1941
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/214 (22%), Positives = 109/214 (50%), Gaps = 5/214 (2%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T ++ + M+ E ++ + +A E++A+ A A + EE+++ Q A +E +
Sbjct: 1732 TKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 1788
Query: 244 NKNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
KN +EQ KDL E ++ L + ++ L +V+++E ++E ++R+ A + L
Sbjct: 1789 KKN-MEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLR 1847
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
+ ++ E + + ++ +D+L ++K + AE+A+ +S+ K ++
Sbjct: 1848 KHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQH 1907
Query: 589 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
ELE AE+R ++++++L + + V + S E
Sbjct: 1908 ELEEAEERADIAESQVNKLRVKSREVHTKVISEE 1941
Score = 58.0 bits (134), Expect = 3e-08
Identities = 49/222 (22%), Positives = 109/222 (49%), Gaps = 9/222 (4%)
Frame = +1
Query: 76 IKKKMQA---MKLEKDNAMDKAD-TCEQQARDANLRAE--KVNEEVRELQKKLAQVEEDL 237
IK K+Q +K + A D+ + E A+ L E ++ +++ +L+ LA+VE++
Sbjct: 915 IKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 974
Query: 238 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 417
+NK++ +++ ++ + E AL QQ +DL+ E++ T + ++ +
Sbjct: 975 HATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLE 1034
Query: 418 QSADENNRMCKVLENRAQQDEERMD-QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 594
Q D+ + E + + D ER +L LK A+ D + + ++ KL E E+
Sbjct: 1035 QQVDDLEGSLE-QEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEI 1093
Query: 595 EVAEDRVKSGDAKISELEEELKVVGNSLKSL--EVSEEKANQ 714
+ +++ A +L++++K + ++ L E+ E+A++
Sbjct: 1094 SNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASR 1135
Score = 48.4 bits (110), Expect = 3e-05
Identities = 35/141 (24%), Positives = 69/141 (48%), Gaps = 7/141 (4%)
Frame = +1
Query: 307 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
TE E+A + + Q+I+++L KSE + ++K++ + ++ + EER
Sbjct: 851 TEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEER 910
Query: 487 MDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
DQL ++KE AED + + E++ K +EDE + + + ++++
Sbjct: 911 CDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 970
Query: 646 EEELKVVGNSLKSLEVSEEKA 708
E+E N +K+L +EE A
Sbjct: 971 EKEKHATENKVKNL--TEEMA 989
Score = 46.8 bits (106), Expect = 8e-05
Identities = 35/226 (15%), Positives = 102/226 (45%), Gaps = 1/226 (0%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++ AT++ ++ + + E +A ++ Q +K+ ++ ++Q ++ +
Sbjct: 1692 EELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDIL 1751
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
++ + K ++A D ++L + A L R + +E+ ++ + R A+Q L
Sbjct: 1752 QEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLAL 1811
Query: 409 EA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
+ ++ + + LE + +++R + L++ ++ +++E + + ++
Sbjct: 1812 KGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQ 1871
Query: 586 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
D ++ + +VKS + E EE+ + L+ E+A +R +
Sbjct: 1872 DLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERAD 1917
Score = 37.9 bits (84), Expect = 0.036
Identities = 44/218 (20%), Positives = 90/218 (41%), Gaps = 10/218 (4%)
Frame = +1
Query: 100 KLEKDNAMDKADTCEQQA--RDANLRAEKVNEEVRELQKKLAQVEEDL---ILNKN-KLE 261
+LEK + + CE QA +A E ++ +Q +L QV+ ++ I K+ +++
Sbjct: 1531 ELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEID 1590
Query: 262 QANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 429
Q ++ + E + +AE+ + N R +++E DL + E + A + EA ++
Sbjct: 1591 QLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYR 1650
Query: 430 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 609
+ K + + L QL A + +E+ L E ++AE
Sbjct: 1651 NTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQ 1710
Query: 610 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ ++ L + + N+ K LE + +E
Sbjct: 1711 ELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEME 1748
Score = 36.3 bits (80), Expect = 0.11
Identities = 47/217 (21%), Positives = 104/217 (47%), Gaps = 1/217 (0%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
MD +K Q + K + ++ + + D ++ ++++ELQ ++ ++EE++
Sbjct: 1073 MDIENEKQQLDEKLKKKEFEISNL-QSKIEDEQALGIQLQKKIKELQARIEELEEEI--- 1128
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+ E+A++ EK++ + L+R++++I E LE E T+ Q + ++ A
Sbjct: 1129 --EAERASRAKAEKQR---------SDLSRELEEISERLE--EAGGATSAQIEMNKKREA 1175
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEA-RLLAEDADGKSDEVSRKLAFVEDELEVA 603
E +M + LE Q E L + ++ L E D V +KL + E+++
Sbjct: 1176 -EFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQID-NLQRVKQKLEKEKSEMKME 1233
Query: 604 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
D + S +S+ + L+ + +L+ ++SE K+ +
Sbjct: 1234 IDDLASNVETVSKAKGNLEKMCRTLED-QLSELKSKE 1269
>M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein.
Length = 1976
Score = 62.5 bits (145), Expect = 1e-09
Identities = 47/193 (24%), Positives = 92/193 (47%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
Q RD R E+ E+ R L K++ ++E +L + + A ++ E L EA++
Sbjct: 1575 QFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIE 1634
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
A N+ ++ + L K + + Q++L EA+ S DE K E + + E + QL
Sbjct: 1635 AANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQE 1694
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 684
+L + A+ + DE++ ++ D + +A+I++LEEEL+ ++++
Sbjct: 1695 ELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMEL 1754
Query: 685 LEVSEEKANQRVE 723
L K +V+
Sbjct: 1755 LNDRFRKTTLQVD 1767
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/217 (20%), Positives = 97/217 (44%)
Frame = +1
Query: 73 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 252
A++ ++ K + D+ + ++ E+ + AE +++ + E K LA + L KN
Sbjct: 1368 ALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE--KALAY--DKLEKTKN 1423
Query: 253 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 432
+L+Q +L++ L + L +K ++ ++ L + + S ++ A+ A E
Sbjct: 1424 RLQQ---ELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEARE 1480
Query: 433 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 612
L ++ E ++ Q K+ R ED D+V + + +E E +
Sbjct: 1481 KETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQ 1540
Query: 613 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
V+ ++ ELE+EL+ ++ LEV+ + + E
Sbjct: 1541 VEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFE 1577
Score = 50.0 bits (114), Expect = 8e-06
Identities = 48/201 (23%), Positives = 90/201 (44%), Gaps = 6/201 (2%)
Frame = +1
Query: 130 ADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK----EKQ 297
A + E Q +D ++ + L ++ Q+EE+ KN L++ ++ EE EKQ
Sbjct: 1310 AASLESQLQDTQELLQEETRQKLNLSSRIRQLEEE----KNSLQEQQEEEEEARKNLEKQ 1365
Query: 298 LTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQD 477
+ A ++++A +KV +E EE + Q +E LE +
Sbjct: 1366 VLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRL 1425
Query: 478 EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED-ELEVAEDRVKSGDAKISELEEE 654
++ +D LT L R +A + + K + + LA + AE+R ++ +A+ E E +
Sbjct: 1426 QQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRA-EAEAREKETK 1484
Query: 655 LKVVGNSL-KSLEVSEEKANQ 714
+ +L ++LE EE Q
Sbjct: 1485 ALSLARALEEALEAKEEFERQ 1505
Score = 50.0 bits (114), Expect = 8e-06
Identities = 46/220 (20%), Positives = 102/220 (46%), Gaps = 6/220 (2%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 222
++ A +A +K+ +A+ L + + A++ + E+Q + E + ++ K + +
Sbjct: 1470 ERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHE 1529
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 390
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E++
Sbjct: 1530 LEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEE 1589
Query: 391 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 570
++ L++ + + + A +++M+ LK+ E A+ DEV ++
Sbjct: 1590 KKRLLIKQVRELEAELEDERKQRALAVASKKKME---IDLKDLEAQIEAANKARDEVIKQ 1646
Query: 571 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
L ++ +++ + ++ A E+ + K LKSLE
Sbjct: 1647 LRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLE 1686
Score = 50.0 bits (114), Expect = 8e-06
Identities = 49/202 (24%), Positives = 86/202 (42%), Gaps = 5/202 (2%)
Frame = +1
Query: 58 AATMDAIKKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED 234
AA A +K A +LE+ N KA E + + K + L+ K+ Q+EE
Sbjct: 1774 AAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKS----KFKATISALEAKIGQLEEQ 1829
Query: 235 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 414
L + ANK + EK+L +V R Q +E +EK+ R +++L EA
Sbjct: 1830 LEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEA 1889
Query: 415 QQSADENNRMCKVLENR---AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
++ A N + L+ A + E + + + LK S R+ +E
Sbjct: 1890 EEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSRSGRRQLHLE 1949
Query: 586 D-ELEVAEDRVKSGDAKISELE 648
LE+++D +S + ++E +
Sbjct: 1950 GASLELSDDDTESKTSDVNETQ 1971
Score = 49.6 bits (113), Expect = 1e-05
Identities = 48/219 (21%), Positives = 106/219 (48%), Gaps = 4/219 (1%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 258
KKKMQA + + +D+ + Q+ L+ EKV E K+ ++EE+++L +++
Sbjct: 945 KKKMQAHIQDLEEQLDEEEGARQK-----LQLEKVTAEA-----KIKKMEEEILLLEDQN 994
Query: 259 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 438
+ K+ + E ++ +++A K + + + K E +++L + +++ E
Sbjct: 995 SKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELE 1054
Query: 439 RMCKVLENRAQQDEERMDQLTNQLKEARL-LAEDADGKSDEVSRKLAFVEDEL---EVAE 606
+ + L+ ++++ +L Q+ E +L LA+ K +E+ LA +DE A
Sbjct: 1055 KAKRKLDGETTDLQDQIAELQAQIDELKLQLAK----KEEELQGALARGDDETLHKNNAL 1110
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
V+ A+I+EL+E+ + S E + ++ +E
Sbjct: 1111 KVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELE 1149
Score = 47.2 bits (107), Expect = 6e-05
Identities = 44/224 (19%), Positives = 115/224 (51%), Gaps = 8/224 (3%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++ ++ +KL+ ++ + D L + VRELQ ++A+++ED +
Sbjct: 1074 LQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDF-----E 1128
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
E+A+++ EK+K+ + E E AL +++ + +E +Q++ E +++ +E
Sbjct: 1129 SEKASRNKAEKQKRDLSEELE--ALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEE 1186
Query: 436 NRMCKV-LENRAQQDEERMDQLTNQLKEARL----LAEDADG---KSDEVSRKLAFVEDE 591
+ + +++ Q+ +++L+ QL++A+ L ++ G + E++ ++ ++
Sbjct: 1187 TKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQV 1246
Query: 592 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+E + K DA++ EL ++ G+ L+ +E++E+ + + E
Sbjct: 1247 KAESEHKRKKLDAQVQELHAKVS-EGDRLR-VELAEKASKLQNE 1288
Score = 46.4 bits (105), Expect = 1e-04
Identities = 61/223 (27%), Positives = 111/223 (49%), Gaps = 6/223 (2%)
Frame = +1
Query: 55 KAATMDAIKKKMQAMKLEKDNAMDKADTCEQQA-RDANLRAEKVNEEVRELQKKLAQVEE 231
+A + +K K + K+E + +++ + QQ + N+ AE++ E EL + ++
Sbjct: 855 QAKDEELLKVKEKQTKVEGE--LEEMERKHQQLLEEKNILAEQLQAET-ELFAEAEEMRA 911
Query: 232 DLILNKNKLEQANKDLE----EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 399
L K +LE+ DLE E+E++ + E + +Q +EE L++ E A+Q
Sbjct: 912 RLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEE----GARQ 967
Query: 400 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 579
KL + +A+ K +E E DQ + +KE +L+ ED + E S +LA
Sbjct: 968 KLQLEKVTAEAK---IKKMEEEILLLE---DQNSKFIKEKKLM-ED---RIAECSSQLAE 1017
Query: 580 VEDELE-VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
E++ + +A+ R K + IS+LEE LK + + LE ++ K
Sbjct: 1018 EEEKAKNLAKIRNKQ-EVMISDLEERLKKEEKTRQELEKAKRK 1059
Score = 38.7 bits (86), Expect = 0.021
Identities = 41/180 (22%), Positives = 78/180 (43%), Gaps = 7/180 (3%)
Frame = +1
Query: 190 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 369
+V +++L +E+L+ K K + +LEE E++ E L ++Q E +
Sbjct: 846 QVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAE 905
Query: 370 SEE---RSGTAQQKLLEA----QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 528
+EE R +Q+L E + +E ++L+N ++ + + L QL E
Sbjct: 906 AEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGA 965
Query: 529 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
+ + K+ +E+E+ + ED+ S K +L E+ + L EEKA
Sbjct: 966 RQKLQLEKVTAEAKIKKMEEEILLLEDQ-NSKFIKEKKLMEDR--IAECSSQLAEEEEKA 1022
Score = 38.7 bits (86), Expect = 0.021
Identities = 35/200 (17%), Positives = 88/200 (44%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A + ++ ++ A K E + + ++ ++ + N + + E +++Q + +EE L
Sbjct: 904 AEAEEMRARLAAKKQELEEILHDLESRVEEEEERN---QILQNEKKKMQAHIQDLEEQLD 960
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
+ ++ + E ++ E E+ L + + ++ + E+R +L E ++
Sbjct: 961 EEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEE 1020
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
A ++ E EER+ + +E DG++ ++ ++A EL+
Sbjct: 1021 KAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIA----ELQA 1076
Query: 601 AEDRVKSGDAKISELEEELK 660
D +K ++++ EEEL+
Sbjct: 1077 QIDELK---LQLAKKEEELQ 1093
>BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,
non-muscle protein.
Length = 1976
Score = 62.5 bits (145), Expect = 1e-09
Identities = 47/193 (24%), Positives = 92/193 (47%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
Q RD R E+ E+ R L K++ ++E +L + + A ++ E L EA++
Sbjct: 1575 QFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIE 1634
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
A N+ ++ + L K + + Q++L EA+ S DE K E + + E + QL
Sbjct: 1635 AANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQE 1694
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 684
+L + A+ + DE++ ++ D + +A+I++LEEEL+ ++++
Sbjct: 1695 ELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMEL 1754
Query: 685 LEVSEEKANQRVE 723
L K +V+
Sbjct: 1755 LNDRFRKTTLQVD 1767
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/217 (20%), Positives = 97/217 (44%)
Frame = +1
Query: 73 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 252
A++ ++ K + D+ + ++ E+ + AE +++ + E K LA + L KN
Sbjct: 1368 ALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE--KALAY--DKLEKTKN 1423
Query: 253 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 432
+L+Q +L++ L + L +K ++ ++ L + + S ++ A+ A E
Sbjct: 1424 RLQQ---ELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEARE 1480
Query: 433 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 612
L ++ E ++ Q K+ R ED D+V + + +E E +
Sbjct: 1481 KETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQ 1540
Query: 613 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
V+ ++ ELE+EL+ ++ LEV+ + + E
Sbjct: 1541 VEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFE 1577
Score = 50.0 bits (114), Expect = 8e-06
Identities = 48/201 (23%), Positives = 90/201 (44%), Gaps = 6/201 (2%)
Frame = +1
Query: 130 ADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK----EKQ 297
A + E Q +D ++ + L ++ Q+EE+ KN L++ ++ EE EKQ
Sbjct: 1310 AASLESQLQDTQELLQEETRQKLNLSSRIRQLEEE----KNSLQEQQEEEEEARKNLEKQ 1365
Query: 298 LTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQD 477
+ A ++++A +KV +E EE + Q +E LE +
Sbjct: 1366 VLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRL 1425
Query: 478 EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED-ELEVAEDRVKSGDAKISELEEE 654
++ +D LT L R +A + + K + + LA + AE+R ++ +A+ E E +
Sbjct: 1426 QQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRA-EAEAREKETK 1484
Query: 655 LKVVGNSL-KSLEVSEEKANQ 714
+ +L ++LE EE Q
Sbjct: 1485 ALSLARALEEALEAKEEFERQ 1505
Score = 50.0 bits (114), Expect = 8e-06
Identities = 46/220 (20%), Positives = 102/220 (46%), Gaps = 6/220 (2%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 222
++ A +A +K+ +A+ L + + A++ + E+Q + E + ++ K + +
Sbjct: 1470 ERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHE 1529
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 390
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E++
Sbjct: 1530 LEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEE 1589
Query: 391 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 570
++ L++ + + + A +++M+ LK+ E A+ DEV ++
Sbjct: 1590 KKRLLIKQVRELEAELEDERKQRALAVASKKKME---IDLKDLEAQIEAANKARDEVIKQ 1646
Query: 571 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
L ++ +++ + ++ A E+ + K LKSLE
Sbjct: 1647 LRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLE 1686
Score = 50.0 bits (114), Expect = 8e-06
Identities = 49/202 (24%), Positives = 86/202 (42%), Gaps = 5/202 (2%)
Frame = +1
Query: 58 AATMDAIKKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED 234
AA A +K A +LE+ N KA E + + K + L+ K+ Q+EE
Sbjct: 1774 AAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKS----KFKATISALEAKIGQLEEQ 1829
Query: 235 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 414
L + ANK + EK+L +V R Q +E +EK+ R +++L EA
Sbjct: 1830 LEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEA 1889
Query: 415 QQSADENNRMCKVLENR---AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
++ A N + L+ A + E + + + LK S R+ +E
Sbjct: 1890 EEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSRSGRRQLHLE 1949
Query: 586 D-ELEVAEDRVKSGDAKISELE 648
LE+++D +S + ++E +
Sbjct: 1950 GASLELSDDDTESKTSDVNETQ 1971
Score = 49.6 bits (113), Expect = 1e-05
Identities = 48/219 (21%), Positives = 106/219 (48%), Gaps = 4/219 (1%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 258
KKKMQA + + +D+ + Q+ L+ EKV E K+ ++EE+++L +++
Sbjct: 945 KKKMQAHIQDLEEQLDEEEGARQK-----LQLEKVTAEA-----KIKKMEEEILLLEDQN 994
Query: 259 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 438
+ K+ + E ++ +++A K + + + K E +++L + +++ E
Sbjct: 995 SKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELE 1054
Query: 439 RMCKVLENRAQQDEERMDQLTNQLKEARL-LAEDADGKSDEVSRKLAFVEDEL---EVAE 606
+ + L+ ++++ +L Q+ E +L LA+ K +E+ LA +DE A
Sbjct: 1055 KAKRKLDGETTDLQDQIAELQAQIDELKLQLAK----KEEELQGALARGDDETLHKNNAL 1110
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
V+ A+I+EL+E+ + S E + ++ +E
Sbjct: 1111 KVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELE 1149
Score = 47.2 bits (107), Expect = 6e-05
Identities = 44/224 (19%), Positives = 115/224 (51%), Gaps = 8/224 (3%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++ ++ +KL+ ++ + D L + VRELQ ++A+++ED +
Sbjct: 1074 LQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDF-----E 1128
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
E+A+++ EK+K+ + E E AL +++ + +E +Q++ E +++ +E
Sbjct: 1129 SEKASRNKAEKQKRDLSEELE--ALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEE 1186
Query: 436 NRMCKV-LENRAQQDEERMDQLTNQLKEARL----LAEDADG---KSDEVSRKLAFVEDE 591
+ + +++ Q+ +++L+ QL++A+ L ++ G + E++ ++ ++
Sbjct: 1187 TKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQV 1246
Query: 592 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+E + K DA++ EL ++ G+ L+ +E++E+ + + E
Sbjct: 1247 KAESEHKRKKLDAQVQELHAKVS-EGDRLR-VELAEKASKLQNE 1288
Score = 46.4 bits (105), Expect = 1e-04
Identities = 61/223 (27%), Positives = 111/223 (49%), Gaps = 6/223 (2%)
Frame = +1
Query: 55 KAATMDAIKKKMQAMKLEKDNAMDKADTCEQQA-RDANLRAEKVNEEVRELQKKLAQVEE 231
+A + +K K + K+E + +++ + QQ + N+ AE++ E EL + ++
Sbjct: 855 QAKDEELLKVKEKQTKVEGE--LEEMERKHQQLLEEKNILAEQLQAET-ELFAEAEEMRA 911
Query: 232 DLILNKNKLEQANKDLE----EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 399
L K +LE+ DLE E+E++ + E + +Q +EE L++ E A+Q
Sbjct: 912 RLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEE----GARQ 967
Query: 400 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 579
KL + +A+ K +E E DQ + +KE +L+ ED + E S +LA
Sbjct: 968 KLQLEKVTAEAK---IKKMEEEILLLE---DQNSKFIKEKKLM-ED---RIAECSSQLAE 1017
Query: 580 VEDELE-VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
E++ + +A+ R K + IS+LEE LK + + LE ++ K
Sbjct: 1018 EEEKAKNLAKIRNKQ-EVMISDLEERLKKEEKTRQELEKAKRK 1059
Score = 38.7 bits (86), Expect = 0.021
Identities = 41/180 (22%), Positives = 78/180 (43%), Gaps = 7/180 (3%)
Frame = +1
Query: 190 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 369
+V +++L +E+L+ K K + +LEE E++ E L ++Q E +
Sbjct: 846 QVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAE 905
Query: 370 SEE---RSGTAQQKLLEA----QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 528
+EE R +Q+L E + +E ++L+N ++ + + L QL E
Sbjct: 906 AEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGA 965
Query: 529 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
+ + K+ +E+E+ + ED+ S K +L E+ + L EEKA
Sbjct: 966 RQKLQLEKVTAEAKIKKMEEEILLLEDQ-NSKFIKEKKLMEDR--IAECSSQLAEEEEKA 1022
Score = 38.7 bits (86), Expect = 0.021
Identities = 35/200 (17%), Positives = 88/200 (44%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A + ++ ++ A K E + + ++ ++ + N + + E +++Q + +EE L
Sbjct: 904 AEAEEMRARLAAKKQELEEILHDLESRVEEEEERN---QILQNEKKKMQAHIQDLEEQLD 960
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
+ ++ + E ++ E E+ L + + ++ + E+R +L E ++
Sbjct: 961 EEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEE 1020
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
A ++ E EER+ + +E DG++ ++ ++A EL+
Sbjct: 1021 KAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIA----ELQA 1076
Query: 601 AEDRVKSGDAKISELEEELK 660
D +K ++++ EEEL+
Sbjct: 1077 QIDELK---LQLAKKEEELQ 1093
>BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,
non-muscle protein.
Length = 1976
Score = 62.5 bits (145), Expect = 1e-09
Identities = 47/193 (24%), Positives = 92/193 (47%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
Q RD R E+ E+ R L K++ ++E +L + + A ++ E L EA++
Sbjct: 1575 QFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIE 1634
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
A N+ ++ + L K + + Q++L EA+ S DE K E + + E + QL
Sbjct: 1635 AANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQE 1694
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 684
+L + A+ + DE++ ++ D + +A+I++LEEEL+ ++++
Sbjct: 1695 ELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMEL 1754
Query: 685 LEVSEEKANQRVE 723
L K +V+
Sbjct: 1755 LNDRFRKTTLQVD 1767
Score = 52.4 bits (120), Expect = 2e-06
Identities = 41/187 (21%), Positives = 87/187 (46%), Gaps = 4/187 (2%)
Frame = +1
Query: 175 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTAT---EAEVAA-LNRKV 342
E+ +++ + + L+Q E+ L +KLE+ L+++ LT + +VA+ L +K
Sbjct: 1391 EEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQEPDDLTVDLDHQRQVASNLEKKQ 1450
Query: 343 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 522
++ ++ L + + S ++ A+ A E L ++ E ++ Q K+ R
Sbjct: 1451 KKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLR 1510
Query: 523 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 702
ED D+V + + +E E +V+ ++ ELE+EL+ ++ LEV+ +
Sbjct: 1511 ADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQ 1570
Query: 703 KANQRVE 723
+ E
Sbjct: 1571 AMKAQFE 1577
Score = 50.0 bits (114), Expect = 8e-06
Identities = 46/220 (20%), Positives = 102/220 (46%), Gaps = 6/220 (2%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 222
++ A +A +K+ +A+ L + + A++ + E+Q + E + ++ K + +
Sbjct: 1470 ERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHE 1529
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 390
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E++
Sbjct: 1530 LEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEE 1589
Query: 391 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 570
++ L++ + + + A +++M+ LK+ E A+ DEV ++
Sbjct: 1590 KKRLLIKQVRELEAELEDERKQRALAVASKKKME---IDLKDLEAQIEAANKARDEVIKQ 1646
Query: 571 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
L ++ +++ + ++ A E+ + K LKSLE
Sbjct: 1647 LRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLE 1686
Score = 50.0 bits (114), Expect = 8e-06
Identities = 49/202 (24%), Positives = 86/202 (42%), Gaps = 5/202 (2%)
Frame = +1
Query: 58 AATMDAIKKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED 234
AA A +K A +LE+ N KA E + + K + L+ K+ Q+EE
Sbjct: 1774 AAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKS----KFKATISALEAKIGQLEEQ 1829
Query: 235 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 414
L + ANK + EK+L +V R Q +E +EK+ R +++L EA
Sbjct: 1830 LEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEA 1889
Query: 415 QQSADENNRMCKVLENR---AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
++ A N + L+ A + E + + + LK S R+ +E
Sbjct: 1890 EEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSRSGRRQLHLE 1949
Query: 586 D-ELEVAEDRVKSGDAKISELE 648
LE+++D +S + ++E +
Sbjct: 1950 GASLELSDDDTESKTSDVNETQ 1971
Score = 49.6 bits (113), Expect = 1e-05
Identities = 48/219 (21%), Positives = 106/219 (48%), Gaps = 4/219 (1%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 258
KKKMQA + + +D+ + Q+ L+ EKV E K+ ++EE+++L +++
Sbjct: 945 KKKMQAHIQDLEEQLDEEEGARQK-----LQLEKVTAEA-----KIKKMEEEILLLEDQN 994
Query: 259 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 438
+ K+ + E ++ +++A K + + + K E +++L + +++ E
Sbjct: 995 SKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELE 1054
Query: 439 RMCKVLENRAQQDEERMDQLTNQLKEARL-LAEDADGKSDEVSRKLAFVEDEL---EVAE 606
+ + L+ ++++ +L Q+ E +L LA+ K +E+ LA +DE A
Sbjct: 1055 KAKRKLDGETTDLQDQIAELQAQIDELKLQLAK----KEEELQGALARGDDETLHKNNAL 1110
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
V+ A+I+EL+E+ + S E + ++ +E
Sbjct: 1111 KVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELE 1149
Score = 48.4 bits (110), Expect = 3e-05
Identities = 48/201 (23%), Positives = 89/201 (44%), Gaps = 6/201 (2%)
Frame = +1
Query: 130 ADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK----EKQ 297
A + E Q +D ++ + L ++ Q+EE+ KN L++ ++ EE EKQ
Sbjct: 1310 AASLESQLQDTQELLQEETRQKLNLSSRIRQLEEE----KNSLQEQQEEEEEARKNLEKQ 1365
Query: 298 LTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQD 477
+ A ++++A +KV +E EE + Q +E LE +
Sbjct: 1366 VLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRL 1425
Query: 478 EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED-ELEVAEDRVKSGDAKISELEEE 654
++ D LT L R +A + + K + + LA + AE+R ++ +A+ E E +
Sbjct: 1426 QQEPDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRA-EAEAREKETK 1484
Query: 655 LKVVGNSL-KSLEVSEEKANQ 714
+ +L ++LE EE Q
Sbjct: 1485 ALSLARALEEALEAKEEFERQ 1505
Score = 47.2 bits (107), Expect = 6e-05
Identities = 44/224 (19%), Positives = 115/224 (51%), Gaps = 8/224 (3%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++ ++ +KL+ ++ + D L + VRELQ ++A+++ED +
Sbjct: 1074 LQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDF-----E 1128
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
E+A+++ EK+K+ + E E AL +++ + +E +Q++ E +++ +E
Sbjct: 1129 SEKASRNKAEKQKRDLSEELE--ALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEE 1186
Query: 436 NRMCKV-LENRAQQDEERMDQLTNQLKEARL----LAEDADG---KSDEVSRKLAFVEDE 591
+ + +++ Q+ +++L+ QL++A+ L ++ G + E++ ++ ++
Sbjct: 1187 TKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQV 1246
Query: 592 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+E + K DA++ EL ++ G+ L+ +E++E+ + + E
Sbjct: 1247 KAESEHKRKKLDAQVQELHAKVS-EGDRLR-VELAEKASKLQNE 1288
Score = 46.4 bits (105), Expect = 1e-04
Identities = 61/223 (27%), Positives = 111/223 (49%), Gaps = 6/223 (2%)
Frame = +1
Query: 55 KAATMDAIKKKMQAMKLEKDNAMDKADTCEQQA-RDANLRAEKVNEEVRELQKKLAQVEE 231
+A + +K K + K+E + +++ + QQ + N+ AE++ E EL + ++
Sbjct: 855 QAKDEELLKVKEKQTKVEGE--LEEMERKHQQLLEEKNILAEQLQAET-ELFAEAEEMRA 911
Query: 232 DLILNKNKLEQANKDLE----EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 399
L K +LE+ DLE E+E++ + E + +Q +EE L++ E A+Q
Sbjct: 912 RLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEE----GARQ 967
Query: 400 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 579
KL + +A+ K +E E DQ + +KE +L+ ED + E S +LA
Sbjct: 968 KLQLEKVTAEAK---IKKMEEEILLLE---DQNSKFIKEKKLM-ED---RIAECSSQLAE 1017
Query: 580 VEDELE-VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
E++ + +A+ R K + IS+LEE LK + + LE ++ K
Sbjct: 1018 EEEKAKNLAKIRNKQ-EVMISDLEERLKKEEKTRQELEKAKRK 1059
Score = 38.7 bits (86), Expect = 0.021
Identities = 41/180 (22%), Positives = 78/180 (43%), Gaps = 7/180 (3%)
Frame = +1
Query: 190 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 369
+V +++L +E+L+ K K + +LEE E++ E L ++Q E +
Sbjct: 846 QVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAE 905
Query: 370 SEE---RSGTAQQKLLEA----QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 528
+EE R +Q+L E + +E ++L+N ++ + + L QL E
Sbjct: 906 AEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGA 965
Query: 529 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
+ + K+ +E+E+ + ED+ S K +L E+ + L EEKA
Sbjct: 966 RQKLQLEKVTAEAKIKKMEEEILLLEDQ-NSKFIKEKKLMEDR--IAECSSQLAEEEEKA 1022
Score = 38.7 bits (86), Expect = 0.021
Identities = 35/200 (17%), Positives = 88/200 (44%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A + ++ ++ A K E + + ++ ++ + N + + E +++Q + +EE L
Sbjct: 904 AEAEEMRARLAAKKQELEEILHDLESRVEEEEERN---QILQNEKKKMQAHIQDLEEQLD 960
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
+ ++ + E ++ E E+ L + + ++ + E+R +L E ++
Sbjct: 961 EEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEE 1020
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
A ++ E EER+ + +E DG++ ++ ++A EL+
Sbjct: 1021 KAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIA----ELQA 1076
Query: 601 AEDRVKSGDAKISELEEELK 660
D +K ++++ EEEL+
Sbjct: 1077 QIDELK---LQLAKKEEELQ 1093
>BC000280-1|AAH00280.1| 471|Homo sapiens MYH10 protein protein.
Length = 471
Score = 62.5 bits (145), Expect = 1e-09
Identities = 47/193 (24%), Positives = 92/193 (47%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
Q RD R E+ E+ R L K++ ++E +L + + A ++ E L EA++
Sbjct: 70 QFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIE 129
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
A N+ ++ + L K + + Q++L EA+ S DE K E + + E + QL
Sbjct: 130 AANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQE 189
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 684
+L + A+ + DE++ ++ D + +A+I++LEEEL+ ++++
Sbjct: 190 ELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMEL 249
Query: 685 LEVSEEKANQRVE 723
L K +V+
Sbjct: 250 LNDRFRKTTLQVD 262
Score = 50.0 bits (114), Expect = 8e-06
Identities = 49/202 (24%), Positives = 86/202 (42%), Gaps = 5/202 (2%)
Frame = +1
Query: 58 AATMDAIKKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED 234
AA A +K A +LE+ N KA E + + K + L+ K+ Q+EE
Sbjct: 269 AAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKS----KFKATISALEAKIGQLEEQ 324
Query: 235 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 414
L + ANK + EK+L +V R Q +E +EK+ R +++L EA
Sbjct: 325 LEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEA 384
Query: 415 QQSADENNRMCKVLENR---AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
++ A N + L+ A + E + + + LK S R+ +E
Sbjct: 385 EEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSRSGRRQLHLE 444
Query: 586 D-ELEVAEDRVKSGDAKISELE 648
LE+++D +S + ++E +
Sbjct: 445 GASLELSDDDTESKTSDVNETQ 466
Score = 41.1 bits (92), Expect = 0.004
Identities = 41/176 (23%), Positives = 80/176 (45%), Gaps = 4/176 (2%)
Frame = +1
Query: 175 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ--- 345
+ V + V EL+K +E+ ++E+ LEE E +L ATE L +Q
Sbjct: 16 DDVGKNVHELEKSKRALEQ-------QVEEMRTQLEELEDELQATEDAKLRLEVNMQAMK 68
Query: 346 -QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 522
Q E DL+ +E++ ++ L++ + + + A +++M+ LK+
Sbjct: 69 AQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKME---IDLKDLE 125
Query: 523 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
E A+ DEV ++L ++ +++ + ++ A E+ + K LKSLE
Sbjct: 126 AQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLE 181
Score = 32.3 bits (70), Expect = 1.8
Identities = 18/71 (25%), Positives = 34/71 (47%)
Frame = +1
Query: 511 KEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
K+ R ED D+V + + +E E +V+ ++ ELE+EL+ ++ LE
Sbjct: 2 KQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLE 61
Query: 691 VSEEKANQRVE 723
V+ + + E
Sbjct: 62 VNMQAMKAQFE 72
>AK097432-1|BAC05050.1| 466|Homo sapiens protein ( Homo sapiens
cDNA FLJ40113 fis, clone TESTI2008621. ).
Length = 466
Score = 62.5 bits (145), Expect = 1e-09
Identities = 49/215 (22%), Positives = 108/215 (50%), Gaps = 2/215 (0%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTC-EQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
++++ +++QA ++E + + + E++ R+ R + E +RE +++L + EE L
Sbjct: 173 LESVGRQLQA-EVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLHEQEERLCE 231
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
+ +L + + L E E++L E + ++ + EE L + EER +++L E ++
Sbjct: 232 QEERLCEQEERLREHEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLCEQEER 291
Query: 424 -ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
++ R+C+ E R ++ EER+ + +L+E + + + E +L E+ L
Sbjct: 292 LCEQEERLCEQ-EERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLRE 350
Query: 601 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
E+R+ + K+ E L+ V L+ EE+
Sbjct: 351 QEERLCEQE-KLPGQERLLEEVEKLLEQERRQEEQ 384
Score = 60.5 bits (140), Expect = 6e-09
Identities = 42/178 (23%), Positives = 86/178 (48%), Gaps = 5/178 (2%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEV-----RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTA 306
E ++ L+AE N ++ R +++L + EE L + +L + + L E+E++L
Sbjct: 172 ELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLHEQEERLCE 231
Query: 307 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
E + ++++ EE L + EER +++L E ++ E + E R + EER
Sbjct: 232 QEERLCEQEERLREHEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLCEQEER 291
Query: 487 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 660
+ + +L E + + + E +L E+ L E+R++ + ++ E EE L+
Sbjct: 292 LCEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLR 349
Score = 58.8 bits (136), Expect = 2e-08
Identities = 46/217 (21%), Positives = 106/217 (48%), Gaps = 1/217 (0%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++K+++++ + ++ R R + E +RE +++L + EE L + +
Sbjct: 169 LRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLHEQEER 228
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS-ADE 432
L + + L E+E++L E + ++++ EE L + EER +++L E ++ ++
Sbjct: 229 LCEQEERLCEQEERLREHEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLCEQ 288
Query: 433 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 612
R+C+ E R + EER+ + +L E + + + E +L E+ L E+R
Sbjct: 289 EERLCEQ-EERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEER 347
Query: 613 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
++ + ++ E +E+L L+ +E E+ ++ E
Sbjct: 348 LREQEERLCE-QEKLPGQERLLEEVEKLLEQERRQEE 383
Score = 50.8 bits (116), Expect = 5e-06
Identities = 44/183 (24%), Positives = 92/183 (50%), Gaps = 2/183 (1%)
Frame = +1
Query: 139 CEQQAR--DANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATE 312
CEQ+ R + R + E +RE +++L + EE L + +L + + L E+E++L E
Sbjct: 286 CEQEERLCEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQE 345
Query: 313 AEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD 492
+ ++ E++ +ER +KLLE ++ +E R+ + E ++ E+ ++
Sbjct: 346 ERLREQEERL--CEQEKLPGQERLLEEVEKLLEQERRQEEQERLLE-RERLLEEVEKLLE 402
Query: 493 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 672
Q Q ++ RLL + + +EV + L ++ + ++R+ + + E+EE L V
Sbjct: 403 QERRQEEQERLL--ERERLLEEVEKLLE--QERRQEEQERLLERERLLDEVEELLDEVEE 458
Query: 673 SLK 681
L+
Sbjct: 459 LLE 461
Score = 47.2 bits (107), Expect = 6e-05
Identities = 34/138 (24%), Positives = 66/138 (47%), Gaps = 1/138 (0%)
Frame = +1
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+++ K+LE +QL A L+ ++ EE L + EER +++L E ++
Sbjct: 163 QDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERL 222
Query: 427 -DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 603
++ R+C+ E R + EER+ + +L E + + + E +L E+ L
Sbjct: 223 HEQEERLCE-QEERLCEQEERLREHEERLCEQEERLREHEERLCEQEERLCEQEERLREQ 281
Query: 604 EDRVKSGDAKISELEEEL 657
E+R+ + ++ E EE L
Sbjct: 282 EERLCEQEERLCEQEERL 299
Score = 44.4 bits (100), Expect = 4e-04
Identities = 35/173 (20%), Positives = 78/173 (45%), Gaps = 1/173 (0%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQ-VEEDLILNKNKLEQANKDLEEKEKQLTATEAE 318
E++ + +L +K+ + +L+ + A+ + + +K+EQ + K+L + +
Sbjct: 121 EEKKHEIHL-VQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQ 179
Query: 319 VAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQL 498
+ A Q + + EER +++L E ++ E E R + EER+ +
Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLHEQEERLCEQEERLCEQ 239
Query: 499 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 657
+L+E + + + E +L E+ L E+R++ + ++ E EE L
Sbjct: 240 EERLREHEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLCEQEERL 292
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/118 (27%), Positives = 62/118 (52%), Gaps = 2/118 (1%)
Frame = +1
Query: 139 CEQQARDANLRAEKVNEEVREL--QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATE 312
CEQ+ E++ EEV +L Q++ + +E L+ + LE+ K LE++ +Q +
Sbjct: 356 CEQEKLPGQ---ERLLEEVEKLLEQERRQEEQERLLERERLLEEVEKLLEQERRQ--EEQ 410
Query: 313 AEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
+ R ++++E+ LE +ER Q++LLE ++ DE + +E +Q+ R
Sbjct: 411 ERLLERERLLEEVEKLLE--QERRQEEQERLLERERLLDEVEELLDEVEELLEQERLR 466
>AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein
protein.
Length = 2018
Score = 62.5 bits (145), Expect = 1e-09
Identities = 47/193 (24%), Positives = 92/193 (47%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
Q RD R E+ E+ R L K++ ++E +L + + A ++ E L EA++
Sbjct: 1617 QFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIE 1676
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
A N+ ++ + L K + + Q++L EA+ S DE K E + + E + QL
Sbjct: 1677 AANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQE 1736
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 684
+L + A+ + DE++ ++ D + +A+I++LEEEL+ ++++
Sbjct: 1737 ELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMEL 1796
Query: 685 LEVSEEKANQRVE 723
L K +V+
Sbjct: 1797 LNDRFRKTTLQVD 1809
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/217 (20%), Positives = 97/217 (44%)
Frame = +1
Query: 73 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 252
A++ ++ K + D+ + ++ E+ + AE +++ + E K LA + L KN
Sbjct: 1410 ALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE--KALAY--DKLEKTKN 1465
Query: 253 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 432
+L+Q +L++ L + L +K ++ ++ L + + S ++ A+ A E
Sbjct: 1466 RLQQ---ELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEARE 1522
Query: 433 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 612
L ++ E ++ Q K+ R ED D+V + + +E E +
Sbjct: 1523 KETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQ 1582
Query: 613 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
V+ ++ ELE+EL+ ++ LEV+ + + E
Sbjct: 1583 VEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFE 1619
Score = 50.0 bits (114), Expect = 8e-06
Identities = 48/201 (23%), Positives = 90/201 (44%), Gaps = 6/201 (2%)
Frame = +1
Query: 130 ADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK----EKQ 297
A + E Q +D ++ + L ++ Q+EE+ KN L++ ++ EE EKQ
Sbjct: 1352 AASLESQLQDTQELLQEETRQKLNLSSRIRQLEEE----KNSLQEQQEEEEEARKNLEKQ 1407
Query: 298 LTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQD 477
+ A ++++A +KV +E EE + Q +E LE +
Sbjct: 1408 VLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRL 1467
Query: 478 EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED-ELEVAEDRVKSGDAKISELEEE 654
++ +D LT L R +A + + K + + LA + AE+R ++ +A+ E E +
Sbjct: 1468 QQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRA-EAEAREKETK 1526
Query: 655 LKVVGNSL-KSLEVSEEKANQ 714
+ +L ++LE EE Q
Sbjct: 1527 ALSLARALEEALEAKEEFERQ 1547
Score = 50.0 bits (114), Expect = 8e-06
Identities = 46/220 (20%), Positives = 102/220 (46%), Gaps = 6/220 (2%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 222
++ A +A +K+ +A+ L + + A++ + E+Q + E + ++ K + +
Sbjct: 1512 ERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHE 1571
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 390
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E++
Sbjct: 1572 LEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEE 1631
Query: 391 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 570
++ L++ + + + A +++M+ LK+ E A+ DEV ++
Sbjct: 1632 KKRLLIKQVRELEAELEDERKQRALAVASKKKME---IDLKDLEAQIEAANKARDEVIKQ 1688
Query: 571 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
L ++ +++ + ++ A E+ + K LKSLE
Sbjct: 1689 LRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLE 1728
Score = 50.0 bits (114), Expect = 8e-06
Identities = 49/202 (24%), Positives = 86/202 (42%), Gaps = 5/202 (2%)
Frame = +1
Query: 58 AATMDAIKKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED 234
AA A +K A +LE+ N KA E + + K + L+ K+ Q+EE
Sbjct: 1816 AAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKS----KFKATISALEAKIGQLEEQ 1871
Query: 235 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 414
L + ANK + EK+L +V R Q +E +EK+ R +++L EA
Sbjct: 1872 LEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEA 1931
Query: 415 QQSADENNRMCKVLENR---AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
++ A N + L+ A + E + + + LK S R+ +E
Sbjct: 1932 EEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSRSGRRQLHLE 1991
Query: 586 D-ELEVAEDRVKSGDAKISELE 648
LE+++D +S + ++E +
Sbjct: 1992 GASLELSDDDTESKTSDVNETQ 2013
Score = 49.6 bits (113), Expect = 1e-05
Identities = 48/219 (21%), Positives = 106/219 (48%), Gaps = 4/219 (1%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 258
KKKMQA + + +D+ + Q+ L+ EKV E K+ ++EE+++L +++
Sbjct: 987 KKKMQAHIQDLEEQLDEEEGARQK-----LQLEKVTAEA-----KIKKMEEEILLLEDQN 1036
Query: 259 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 438
+ K+ + E ++ +++A K + + + K E +++L + +++ E
Sbjct: 1037 SKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELE 1096
Query: 439 RMCKVLENRAQQDEERMDQLTNQLKEARL-LAEDADGKSDEVSRKLAFVEDEL---EVAE 606
+ + L+ ++++ +L Q+ E +L LA+ K +E+ LA +DE A
Sbjct: 1097 KAKRKLDGETTDLQDQIAELQAQIDELKLQLAK----KEEELQGALARGDDETLHKNNAL 1152
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
V+ A+I+EL+E+ + S E + ++ +E
Sbjct: 1153 KVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELE 1191
Score = 47.2 bits (107), Expect = 6e-05
Identities = 44/224 (19%), Positives = 115/224 (51%), Gaps = 8/224 (3%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++ ++ +KL+ ++ + D L + VRELQ ++A+++ED +
Sbjct: 1116 LQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDF-----E 1170
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
E+A+++ EK+K+ + E E AL +++ + +E +Q++ E +++ +E
Sbjct: 1171 SEKASRNKAEKQKRDLSEELE--ALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEE 1228
Query: 436 NRMCKV-LENRAQQDEERMDQLTNQLKEARL----LAEDADG---KSDEVSRKLAFVEDE 591
+ + +++ Q+ +++L+ QL++A+ L ++ G + E++ ++ ++
Sbjct: 1229 TKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQV 1288
Query: 592 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+E + K DA++ EL ++ G+ L+ +E++E+ + + E
Sbjct: 1289 KAESEHKRKKLDAQVQELHAKVS-EGDRLR-VELAEKASKLQNE 1330
Score = 46.4 bits (105), Expect = 1e-04
Identities = 61/223 (27%), Positives = 111/223 (49%), Gaps = 6/223 (2%)
Frame = +1
Query: 55 KAATMDAIKKKMQAMKLEKDNAMDKADTCEQQA-RDANLRAEKVNEEVRELQKKLAQVEE 231
+A + +K K + K+E + +++ + QQ + N+ AE++ E EL + ++
Sbjct: 897 QAKDEELLKVKEKQTKVEGE--LEEMERKHQQLLEEKNILAEQLQAET-ELFAEAEEMRA 953
Query: 232 DLILNKNKLEQANKDLE----EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 399
L K +LE+ DLE E+E++ + E + +Q +EE L++ E A+Q
Sbjct: 954 RLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEE----GARQ 1009
Query: 400 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 579
KL + +A+ K +E E DQ + +KE +L+ ED + E S +LA
Sbjct: 1010 KLQLEKVTAEAK---IKKMEEEILLLE---DQNSKFIKEKKLM-ED---RIAECSSQLAE 1059
Query: 580 VEDELE-VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
E++ + +A+ R K + IS+LEE LK + + LE ++ K
Sbjct: 1060 EEEKAKNLAKIRNKQ-EVMISDLEERLKKEEKTRQELEKAKRK 1101
Score = 38.7 bits (86), Expect = 0.021
Identities = 41/180 (22%), Positives = 78/180 (43%), Gaps = 7/180 (3%)
Frame = +1
Query: 190 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 369
+V +++L +E+L+ K K + +LEE E++ E L ++Q E +
Sbjct: 888 QVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAE 947
Query: 370 SEE---RSGTAQQKLLEA----QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 528
+EE R +Q+L E + +E ++L+N ++ + + L QL E
Sbjct: 948 AEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGA 1007
Query: 529 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
+ + K+ +E+E+ + ED+ S K +L E+ + L EEKA
Sbjct: 1008 RQKLQLEKVTAEAKIKKMEEEILLLEDQ-NSKFIKEKKLMEDR--IAECSSQLAEEEEKA 1064
Score = 38.7 bits (86), Expect = 0.021
Identities = 35/200 (17%), Positives = 88/200 (44%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A + ++ ++ A K E + + ++ ++ + N + + E +++Q + +EE L
Sbjct: 946 AEAEEMRARLAAKKQELEEILHDLESRVEEEEERN---QILQNEKKKMQAHIQDLEEQLD 1002
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
+ ++ + E ++ E E+ L + + ++ + E+R +L E ++
Sbjct: 1003 EEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEE 1062
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
A ++ E EER+ + +E DG++ ++ ++A EL+
Sbjct: 1063 KAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIA----ELQA 1118
Query: 601 AEDRVKSGDAKISELEEELK 660
D +K ++++ EEEL+
Sbjct: 1119 QIDELK---LQLAKKEEELQ 1135
>X13939-1|CAA32122.1| 328|Homo sapiens laminin B2 protein.
Length = 328
Score = 62.1 bits (144), Expect = 2e-09
Identities = 46/172 (26%), Positives = 77/172 (44%), Gaps = 6/172 (3%)
Frame = +1
Query: 163 NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 342
N + NE+ RE Q+ L D KNK +A + +K T+T+AE +V
Sbjct: 114 NQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEV 173
Query: 343 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 522
++ ++ ++ A+++L Q AD++ M + AQ+ E + N +
Sbjct: 174 TDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLL 233
Query: 523 LLAED---ADGKSDEVS-RKLAFVEDELEVAEDRVKSG--DAKISELEEELK 660
+ D G+ D V KL +E L A+D +K D K+S+LE E K
Sbjct: 234 SIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAK 285
Score = 47.6 bits (108), Expect = 4e-05
Identities = 43/186 (23%), Positives = 75/186 (40%)
Frame = +1
Query: 52 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 231
QK + +++ M+ +LE N ++K T +Q A RA+ E KK
Sbjct: 21 QKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAKK----GR 76
Query: 232 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 411
D + N + KD + + T AE A RK+ I + + ++ E++ AQQ L
Sbjct: 77 DTLQEANDILNNLKDFDRRVND-NKTAAEEAL--RKIPAINQTITEANEKTREAQQALGS 133
Query: 412 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 591
A A E E A ++ + + D D + + + ++L E E
Sbjct: 134 AAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKE 193
Query: 592 LEVAED 609
L+ +D
Sbjct: 194 LKRKQD 199
>X03740-1|CAA27380.1| 876|Homo sapiens protein ( Human skeletal mRNA
for myosin heavy chain light meromyosin region. ).
Length = 876
Score = 62.1 bits (144), Expect = 2e-09
Identities = 49/216 (22%), Positives = 112/216 (51%), Gaps = 7/216 (3%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T ++ + ++ E ++ + +A E++A+ A A + EE+++ Q A +E +
Sbjct: 667 TKKKLETDISQIQGEMEDIIKEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 723
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
KN LEQ KDL+ + + A + + +++Q++E + + E + Q++ +EA +
Sbjct: 724 KKN-LEQTVKDLQHRLDE--AEQLALKGGKKQIQKLEAKVRELEGEVESEQKRNVEAVKG 780
Query: 424 ADENNRMCKVLENRAQQD-------EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 582
++ R K L + ++D ++ +D+L ++K + AE+A+ +S+ K +
Sbjct: 781 LHKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRI 840
Query: 583 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
+ ELE AE+R ++++++L + + V + S E
Sbjct: 841 QHELEEAEERADIAESQVNKLRVKSREVHTKIISEE 876
Score = 48.0 bits (109), Expect = 3e-05
Identities = 35/226 (15%), Positives = 103/226 (45%), Gaps = 1/226 (0%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++ AT++ ++ + + E +A ++ Q +K+ ++ ++Q ++ +
Sbjct: 627 EELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDII 686
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
++ + K ++A D ++L + A L R + +E+ ++ + R A+Q L
Sbjct: 687 KEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLAL 746
Query: 409 EA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
+ ++ + + LE + +++R + L + ++ +++E + + ++
Sbjct: 747 KGGKKQIQKLEAKVRELEGEVESEQKRNVEAVKGLHKHERKVKELTYQTEEDRKNILRLQ 806
Query: 586 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
D ++ + +VKS + E EE+ V + + ++ E+A +R +
Sbjct: 807 DLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERAD 852
Score = 39.5 bits (88), Expect = 0.012
Identities = 38/228 (16%), Positives = 104/228 (45%), Gaps = 4/228 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
Q+K+ A+++ +++ E+ + Q + + + + +EE+ ++++ ++E
Sbjct: 476 QEKSELQAALEEAEASLEHEEGKILRIQLEVNQVKSEVDRKIAEKDEEIDQMKRNHIRIE 535
Query: 229 EDLILNKNKLEQANKD---LEEK-EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 396
E + N ++ D L++K E L E ++ NR + + + ++ Q
Sbjct: 536 ESMQSTLNAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEDLRNYQNTQAILKDTQ 595
Query: 397 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLA 576
L +A +S ++ ++E RA + +++L L++ + A+ + + S ++
Sbjct: 596 LHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQ 655
Query: 577 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ + + K + IS+++ E++ + +K +EEKA + +
Sbjct: 656 LLHTQNTSLINTKKKLETDISQIQGEMEDI---IKEARNAEEKAKKAI 700
Score = 32.7 bits (71), Expect = 1.4
Identities = 46/225 (20%), Positives = 100/225 (44%), Gaps = 5/225 (2%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
+ MD K Q + K + + + + D ++ ++++ELQ ++ ++EE++
Sbjct: 6 SAMDIENDKQQLDEKLKKKEFEMSGL-QSKIEDEQALGMQLQKKIKELQARIEELEEEI- 63
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
+A + K ++L + L+R++++I E LE E T+ Q + ++
Sbjct: 64 -------EAERTSRAKAEKLRSD------LSRELEEISERLE--EAVGATSTQIEMNKKR 108
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEA-RLLAEDADGKSDEVSRKLAFVEDELE 597
A E +M + LE Q E L + ++ L E D V +KL + E++
Sbjct: 109 EA-EFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQID-NLQRVKQKLEKEKSEMK 166
Query: 598 VAEDRVKSGDAKISE----LEEELKVVGNSLKSLEVSEEKANQRV 720
+ D + S +S+ LE+ + + + L ++ EE+ + +
Sbjct: 167 MEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLI 211
>M55210-1|AAA59492.1| 1609|Homo sapiens laminin B2 chain protein.
Length = 1609
Score = 62.1 bits (144), Expect = 2e-09
Identities = 46/172 (26%), Positives = 77/172 (44%), Gaps = 6/172 (3%)
Frame = +1
Query: 163 NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 342
N + NE+ RE Q+ L D KNK +A + +K T+T+AE +V
Sbjct: 1395 NQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEV 1454
Query: 343 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 522
++ ++ ++ A+++L Q AD++ M + AQ+ E + N +
Sbjct: 1455 TDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLL 1514
Query: 523 LLAED---ADGKSDEVS-RKLAFVEDELEVAEDRVKSG--DAKISELEEELK 660
+ D G+ D V KL +E L A+D +K D K+S+LE E K
Sbjct: 1515 SIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAK 1566
Score = 47.6 bits (108), Expect = 4e-05
Identities = 43/186 (23%), Positives = 75/186 (40%)
Frame = +1
Query: 52 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 231
QK + +++ M+ +LE N ++K T +Q A RA+ E KK
Sbjct: 1302 QKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAKK----GR 1357
Query: 232 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 411
D + N + KD + + T AE A RK+ I + + ++ E++ AQQ L
Sbjct: 1358 DTLQEANDILNNLKDFDRRVND-NKTAAEEAL--RKIPAINQTITEANEKTREAQQALGS 1414
Query: 412 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 591
A A E E A ++ + + D D + + + ++L E E
Sbjct: 1415 AAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKE 1474
Query: 592 LEVAED 609
L+ +D
Sbjct: 1475 LKRKQD 1480
Score = 40.3 bits (90), Expect = 0.007
Identities = 48/242 (19%), Positives = 101/242 (41%), Gaps = 15/242 (6%)
Frame = +1
Query: 34 STGP*QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDA-NLRAEKV---NE---E 192
STG + +K + K E D+ + A T + +A NL + N+ E
Sbjct: 1169 STGDPNNMTLLAEEARKLAERHKQEADDIVRVAKTANDTSTEAYNLLLRTLAGENQTAFE 1228
Query: 193 VRELQKKLAQ---VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 363
+ EL +K Q + +DL ++ + K +K ++ A+ A+++ L+ + + E +
Sbjct: 1229 IEELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASVAQLSPLDSETLENEANN 1288
Query: 364 EKSEERS--GTAQQKLLEAQQSADE---NNRMCKVLENRAQQDEERMDQLTNQLKEARLL 528
K E + QKL + + ++ K L + + +++ DQL + A+ L
Sbjct: 1289 IKMEAENLEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKAL 1348
Query: 529 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
AE+A K + ++ + + L+ + RV E ++ + ++ +A
Sbjct: 1349 AEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAINQTITEANEKTREA 1408
Query: 709 NQ 714
Q
Sbjct: 1409 QQ 1410
Score = 37.5 bits (83), Expect = 0.048
Identities = 29/141 (20%), Positives = 57/141 (40%), Gaps = 2/141 (1%)
Frame = +1
Query: 124 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 303
D+ E++ D A+ V + + L +L +V L ++L+ +EE
Sbjct: 1073 DRLKEAEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAE 1132
Query: 304 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR--AQQD 477
A V R ++ +LEK+ + A + + + + D NN E R A++
Sbjct: 1133 QARAHVENTERLIEIASRELEKA--KVAAANVSVTQPESTGDPNNMTLLAEEARKLAERH 1190
Query: 478 EERMDQLTNQLKEARLLAEDA 540
++ D + K A + +A
Sbjct: 1191 KQEADDIVRVAKTANDTSTEA 1211
Score = 37.1 bits (82), Expect = 0.064
Identities = 46/235 (19%), Positives = 102/235 (43%), Gaps = 15/235 (6%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T A + +++ + E + + +A + ++ R ++VN + +L + +
Sbjct: 1067 TDQAFEDRLKEAEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEE 1126
Query: 244 NKNKLEQANKDLEEKEK--QLTATE---AEVAALNRKVQQIEEDLEKSE-ERSGTAQQKL 405
N EQA +E E+ ++ + E A+VAA N V Q E + + +KL
Sbjct: 1127 TGNLAEQARAHVENTERLIEIASRELEKAKVAAANVSVTQPESTGDPNNMTLLAEEARKL 1186
Query: 406 LEA-QQSADENNRMCKVLENRAQQDEERM-------DQLTNQLKEARLLAEDADGKSDEV 561
E +Q AD+ R+ K + + + + +Q +++E E A S ++
Sbjct: 1187 AERHKQEADDIVRVAKTANDTSTEAYNLLLRTLAGENQTAFEIEELNRKYEQAKNISQDL 1246
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEE-ELKVVGNSLKSLEVSEEKANQRVE 723
++ A V +E + A D+ A +++L + + + N ++++ E Q ++
Sbjct: 1247 EKQAARVHEEAKRAGDKAVEIYASVAQLSPLDSETLENEANNIKMEAENLEQLID 1301
>M27654-1|AAA59489.1| 217|Homo sapiens laminin B2 protein.
Length = 217
Score = 62.1 bits (144), Expect = 2e-09
Identities = 46/172 (26%), Positives = 77/172 (44%), Gaps = 6/172 (3%)
Frame = +1
Query: 163 NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 342
N + NE+ RE Q+ L D KNK +A + +K T+T+AE +V
Sbjct: 3 NQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEV 62
Query: 343 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 522
++ ++ ++ A+++L Q AD++ M + AQ+ E + N +
Sbjct: 63 TDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLL 122
Query: 523 LLAED---ADGKSDEVS-RKLAFVEDELEVAEDRVKSG--DAKISELEEELK 660
+ D G+ D V KL +E L A+D +K D K+S+LE E K
Sbjct: 123 SIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAK 174
>J03202-1|AAA59488.1| 1609|Homo sapiens LAMB2 protein.
Length = 1609
Score = 62.1 bits (144), Expect = 2e-09
Identities = 46/172 (26%), Positives = 77/172 (44%), Gaps = 6/172 (3%)
Frame = +1
Query: 163 NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 342
N + NE+ RE Q+ L D KNK +A + +K T+T+AE +V
Sbjct: 1395 NQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEV 1454
Query: 343 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 522
++ ++ ++ A+++L Q AD++ M + AQ+ E + N +
Sbjct: 1455 TDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLL 1514
Query: 523 LLAED---ADGKSDEVS-RKLAFVEDELEVAEDRVKSG--DAKISELEEELK 660
+ D G+ D V KL +E L A+D +K D K+S+LE E K
Sbjct: 1515 SIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAK 1566
Score = 47.6 bits (108), Expect = 4e-05
Identities = 43/186 (23%), Positives = 75/186 (40%)
Frame = +1
Query: 52 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 231
QK + +++ M+ +LE N ++K T +Q A RA+ E KK
Sbjct: 1302 QKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAKK----GR 1357
Query: 232 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 411
D + N + KD + + T AE A RK+ I + + ++ E++ AQQ L
Sbjct: 1358 DTLQEANDILNNLKDFDRRVND-NKTAAEEAL--RKIPAINQTITEANEKTREAQQALGS 1414
Query: 412 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 591
A A E E A ++ + + D D + + + ++L E E
Sbjct: 1415 AAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKE 1474
Query: 592 LEVAED 609
L+ +D
Sbjct: 1475 LKRKQD 1480
Score = 40.3 bits (90), Expect = 0.007
Identities = 48/242 (19%), Positives = 101/242 (41%), Gaps = 15/242 (6%)
Frame = +1
Query: 34 STGP*QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDA-NLRAEKV---NE---E 192
STG + +K + K E D+ + A T + +A NL + N+ E
Sbjct: 1169 STGDPNNMTLLAEEARKLAERHKQEADDIVRVAKTANDTSTEAYNLLLRTLAGENQTAFE 1228
Query: 193 VRELQKKLAQ---VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 363
+ EL +K Q + +DL ++ + K +K ++ A+ A+++ L+ + + E +
Sbjct: 1229 IEELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASVAQLSPLDSETLENEANN 1288
Query: 364 EKSEERS--GTAQQKLLEAQQSADE---NNRMCKVLENRAQQDEERMDQLTNQLKEARLL 528
K E + QKL + + ++ K L + + +++ DQL + A+ L
Sbjct: 1289 IKMEAENLEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKAL 1348
Query: 529 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
AE+A K + ++ + + L+ + RV E ++ + ++ +A
Sbjct: 1349 AEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAINQTITEANEKTREA 1408
Query: 709 NQ 714
Q
Sbjct: 1409 QQ 1410
Score = 37.5 bits (83), Expect = 0.048
Identities = 29/141 (20%), Positives = 57/141 (40%), Gaps = 2/141 (1%)
Frame = +1
Query: 124 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 303
D+ E++ D A+ V + + L +L +V L ++L+ +EE
Sbjct: 1073 DRLKEAEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAE 1132
Query: 304 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR--AQQD 477
A V R ++ +LEK+ + A + + + + D NN E R A++
Sbjct: 1133 QARAHVENTERLIEIASRELEKA--KVAAANVSVTQPESTGDPNNMTLLAEEARKLAERH 1190
Query: 478 EERMDQLTNQLKEARLLAEDA 540
++ D + K A + +A
Sbjct: 1191 KQEADDIVRVAKTANDTSTEA 1211
Score = 37.1 bits (82), Expect = 0.064
Identities = 46/235 (19%), Positives = 102/235 (43%), Gaps = 15/235 (6%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T A + +++ + E + + +A + ++ R ++VN + +L + +
Sbjct: 1067 TDQAFEDRLKEAEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEE 1126
Query: 244 NKNKLEQANKDLEEKEK--QLTATE---AEVAALNRKVQQIEEDLEKSE-ERSGTAQQKL 405
N EQA +E E+ ++ + E A+VAA N V Q E + + +KL
Sbjct: 1127 TGNLAEQARAHVENTERLIEIASRELEKAKVAAANVSVTQPESTGDPNNMTLLAEEARKL 1186
Query: 406 LEA-QQSADENNRMCKVLENRAQQDEERM-------DQLTNQLKEARLLAEDADGKSDEV 561
E +Q AD+ R+ K + + + + +Q +++E E A S ++
Sbjct: 1187 AERHKQEADDIVRVAKTANDTSTEAYNLLLRTLAGENQTAFEIEELNRKYEQAKNISQDL 1246
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEE-ELKVVGNSLKSLEVSEEKANQRVE 723
++ A V +E + A D+ A +++L + + + N ++++ E Q ++
Sbjct: 1247 EKQAARVHEEAKRAGDKAVEIYASVAQLSPLDSETLENEANNIKMEAENLEQLID 1301
>AL450304-5|CAI14877.1| 1609|Homo sapiens laminin, gamma 1 (formerly
LAMB2) protein.
Length = 1609
Score = 62.1 bits (144), Expect = 2e-09
Identities = 46/172 (26%), Positives = 77/172 (44%), Gaps = 6/172 (3%)
Frame = +1
Query: 163 NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 342
N + NE+ RE Q+ L D KNK +A + +K T+T+AE +V
Sbjct: 1395 NQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEV 1454
Query: 343 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 522
++ ++ ++ A+++L Q AD++ M + AQ+ E + N +
Sbjct: 1455 TDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLL 1514
Query: 523 LLAED---ADGKSDEVS-RKLAFVEDELEVAEDRVKSG--DAKISELEEELK 660
+ D G+ D V KL +E L A+D +K D K+S+LE E K
Sbjct: 1515 SIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAK 1566
Score = 47.6 bits (108), Expect = 4e-05
Identities = 43/186 (23%), Positives = 75/186 (40%)
Frame = +1
Query: 52 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 231
QK + +++ M+ +LE N ++K T +Q A RA+ E KK
Sbjct: 1302 QKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAKK----GR 1357
Query: 232 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 411
D + N + KD + + T AE A RK+ I + + ++ E++ AQQ L
Sbjct: 1358 DTLQEANDILNNLKDFDRRVND-NKTAAEEAL--RKIPAINQTITEANEKTREAQQALGS 1414
Query: 412 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 591
A A E E A ++ + + D D + + + ++L E E
Sbjct: 1415 AAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKE 1474
Query: 592 LEVAED 609
L+ +D
Sbjct: 1475 LKRKQD 1480
Score = 40.3 bits (90), Expect = 0.007
Identities = 48/242 (19%), Positives = 101/242 (41%), Gaps = 15/242 (6%)
Frame = +1
Query: 34 STGP*QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDA-NLRAEKV---NE---E 192
STG + +K + K E D+ + A T + +A NL + N+ E
Sbjct: 1169 STGDPNNMTLLAEEARKLAERHKQEADDIVRVAKTANDTSTEAYNLLLRTLAGENQTAFE 1228
Query: 193 VRELQKKLAQ---VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 363
+ EL +K Q + +DL ++ + K +K ++ A+ A+++ L+ + + E +
Sbjct: 1229 IEELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASVAQLSPLDSETLENEANN 1288
Query: 364 EKSEERS--GTAQQKLLEAQQSADE---NNRMCKVLENRAQQDEERMDQLTNQLKEARLL 528
K E + QKL + + ++ K L + + +++ DQL + A+ L
Sbjct: 1289 IKMEAENLEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKAL 1348
Query: 529 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
AE+A K + ++ + + L+ + RV E ++ + ++ +A
Sbjct: 1349 AEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAINQTITEANEKTREA 1408
Query: 709 NQ 714
Q
Sbjct: 1409 QQ 1410
Score = 37.5 bits (83), Expect = 0.048
Identities = 29/141 (20%), Positives = 57/141 (40%), Gaps = 2/141 (1%)
Frame = +1
Query: 124 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 303
D+ E++ D A+ V + + L +L +V L ++L+ +EE
Sbjct: 1073 DRLKEAEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAE 1132
Query: 304 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR--AQQD 477
A V R ++ +LEK+ + A + + + + D NN E R A++
Sbjct: 1133 QARAHVENTERLIEIASRELEKA--KVAAANVSVTQPESTGDPNNMTLLAEEARKLAERH 1190
Query: 478 EERMDQLTNQLKEARLLAEDA 540
++ D + K A + +A
Sbjct: 1191 KQEADDIVRVAKTANDTSTEA 1211
Score = 37.1 bits (82), Expect = 0.064
Identities = 46/235 (19%), Positives = 102/235 (43%), Gaps = 15/235 (6%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T A + +++ + E + + +A + ++ R ++VN + +L + +
Sbjct: 1067 TDQAFEDRLKEAEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEE 1126
Query: 244 NKNKLEQANKDLEEKEK--QLTATE---AEVAALNRKVQQIEEDLEKSE-ERSGTAQQKL 405
N EQA +E E+ ++ + E A+VAA N V Q E + + +KL
Sbjct: 1127 TGNLAEQARAHVENTERLIEIASRELEKAKVAAANVSVTQPESTGDPNNMTLLAEEARKL 1186
Query: 406 LEA-QQSADENNRMCKVLENRAQQDEERM-------DQLTNQLKEARLLAEDADGKSDEV 561
E +Q AD+ R+ K + + + + +Q +++E E A S ++
Sbjct: 1187 AERHKQEADDIVRVAKTANDTSTEAYNLLLRTLAGENQTAFEIEELNRKYEQAKNISQDL 1246
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEE-ELKVVGNSLKSLEVSEEKANQRVE 723
++ A V +E + A D+ A +++L + + + N ++++ E Q ++
Sbjct: 1247 EKQAARVHEEAKRAGDKAVEIYASVAQLSPLDSETLENEANNIKMEAENLEQLID 1301
>AL354953-3|CAH70981.1| 1609|Homo sapiens laminin, gamma 1 (formerly
LAMB2) protein.
Length = 1609
Score = 62.1 bits (144), Expect = 2e-09
Identities = 46/172 (26%), Positives = 77/172 (44%), Gaps = 6/172 (3%)
Frame = +1
Query: 163 NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 342
N + NE+ RE Q+ L D KNK +A + +K T+T+AE +V
Sbjct: 1395 NQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEV 1454
Query: 343 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 522
++ ++ ++ A+++L Q AD++ M + AQ+ E + N +
Sbjct: 1455 TDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLL 1514
Query: 523 LLAED---ADGKSDEVS-RKLAFVEDELEVAEDRVKSG--DAKISELEEELK 660
+ D G+ D V KL +E L A+D +K D K+S+LE E K
Sbjct: 1515 SIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAK 1566
Score = 47.6 bits (108), Expect = 4e-05
Identities = 43/186 (23%), Positives = 75/186 (40%)
Frame = +1
Query: 52 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 231
QK + +++ M+ +LE N ++K T +Q A RA+ E KK
Sbjct: 1302 QKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAKK----GR 1357
Query: 232 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 411
D + N + KD + + T AE A RK+ I + + ++ E++ AQQ L
Sbjct: 1358 DTLQEANDILNNLKDFDRRVND-NKTAAEEAL--RKIPAINQTITEANEKTREAQQALGS 1414
Query: 412 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 591
A A E E A ++ + + D D + + + ++L E E
Sbjct: 1415 AAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKE 1474
Query: 592 LEVAED 609
L+ +D
Sbjct: 1475 LKRKQD 1480
Score = 40.3 bits (90), Expect = 0.007
Identities = 48/242 (19%), Positives = 101/242 (41%), Gaps = 15/242 (6%)
Frame = +1
Query: 34 STGP*QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDA-NLRAEKV---NE---E 192
STG + +K + K E D+ + A T + +A NL + N+ E
Sbjct: 1169 STGDPNNMTLLAEEARKLAERHKQEADDIVRVAKTANDTSTEAYNLLLRTLAGENQTAFE 1228
Query: 193 VRELQKKLAQ---VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 363
+ EL +K Q + +DL ++ + K +K ++ A+ A+++ L+ + + E +
Sbjct: 1229 IEELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASVAQLSPLDSETLENEANN 1288
Query: 364 EKSEERS--GTAQQKLLEAQQSADE---NNRMCKVLENRAQQDEERMDQLTNQLKEARLL 528
K E + QKL + + ++ K L + + +++ DQL + A+ L
Sbjct: 1289 IKMEAENLEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKAL 1348
Query: 529 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
AE+A K + ++ + + L+ + RV E ++ + ++ +A
Sbjct: 1349 AEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAINQTITEANEKTREA 1408
Query: 709 NQ 714
Q
Sbjct: 1409 QQ 1410
Score = 37.5 bits (83), Expect = 0.048
Identities = 29/141 (20%), Positives = 57/141 (40%), Gaps = 2/141 (1%)
Frame = +1
Query: 124 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 303
D+ E++ D A+ V + + L +L +V L ++L+ +EE
Sbjct: 1073 DRLKEAEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAE 1132
Query: 304 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR--AQQD 477
A V R ++ +LEK+ + A + + + + D NN E R A++
Sbjct: 1133 QARAHVENTERLIEIASRELEKA--KVAAANVSVTQPESTGDPNNMTLLAEEARKLAERH 1190
Query: 478 EERMDQLTNQLKEARLLAEDA 540
++ D + K A + +A
Sbjct: 1191 KQEADDIVRVAKTANDTSTEA 1211
Score = 37.1 bits (82), Expect = 0.064
Identities = 46/235 (19%), Positives = 102/235 (43%), Gaps = 15/235 (6%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T A + +++ + E + + +A + ++ R ++VN + +L + +
Sbjct: 1067 TDQAFEDRLKEAEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEE 1126
Query: 244 NKNKLEQANKDLEEKEK--QLTATE---AEVAALNRKVQQIEEDLEKSE-ERSGTAQQKL 405
N EQA +E E+ ++ + E A+VAA N V Q E + + +KL
Sbjct: 1127 TGNLAEQARAHVENTERLIEIASRELEKAKVAAANVSVTQPESTGDPNNMTLLAEEARKL 1186
Query: 406 LEA-QQSADENNRMCKVLENRAQQDEERM-------DQLTNQLKEARLLAEDADGKSDEV 561
E +Q AD+ R+ K + + + + +Q +++E E A S ++
Sbjct: 1187 AERHKQEADDIVRVAKTANDTSTEAYNLLLRTLAGENQTAFEIEELNRKYEQAKNISQDL 1246
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEE-ELKVVGNSLKSLEVSEEKANQRVE 723
++ A V +E + A D+ A +++L + + + N ++++ E Q ++
Sbjct: 1247 EKQAARVHEEAKRAGDKAVEIYASVAQLSPLDSETLENEANNIKMEAENLEQLID 1301
>Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein.
Length = 1937
Score = 61.7 bits (143), Expect = 3e-09
Identities = 45/212 (21%), Positives = 107/212 (50%), Gaps = 5/212 (2%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T ++ + ++ E + + ++ E++A+ A A + EE+++ Q A +E +
Sbjct: 1729 TKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 1785
Query: 244 NKNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
KN LEQ KDL E ++ L + ++ L +V+++E ++E ++R+ A + L
Sbjct: 1786 KKN-LEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLR 1844
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
+ ++ E + + ++ +D+L ++K + AE+A+ +S+ K ++
Sbjct: 1845 KHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQH 1904
Query: 589 ELEVAEDRVKSGDAKISELEEELKVVGNSLKS 684
ELE AE+R ++++++L + + V + +
Sbjct: 1905 ELEEAEERAHIAESQVNKLRVKSREVHTKISA 1936
Score = 58.0 bits (134), Expect = 3e-08
Identities = 57/229 (24%), Positives = 104/229 (45%), Gaps = 7/229 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+++ +A+ +Q+ + + D ++ + ++ + K N EV + + K E
Sbjct: 1323 EEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKY---E 1379
Query: 229 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 387
D I +LE+A K L +E E+ + A A+ A+L + Q+++ EDL ERS
Sbjct: 1380 TDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSN 1439
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
A L + Q++ D KVL Q+ EE +L KE+R L+ + +
Sbjct: 1440 AACAALDKKQRNFD------KVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEE 1493
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
L D+LE K+ +IS+L E++ G + LE +++ Q
Sbjct: 1494 SL----DQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQ 1538
Score = 54.0 bits (124), Expect = 5e-07
Identities = 53/241 (21%), Positives = 114/241 (47%), Gaps = 16/241 (6%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQV 225
++K T+ K +Q ++ E D+ D + CEQ ++ ++ E +EV E ++ ++
Sbjct: 877 EEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKN-KIQLEAKIKEVTERAEEEEEI 935
Query: 226 EEDLILNKNKLE----QANKDLEEKE-------KQLTATEAEVAALNRKVQQIEEDLEK- 369
+L K KLE + KD+++ E K+ ATE +V L ++ ++E + K
Sbjct: 936 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKL 995
Query: 370 SEERSG---TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA 540
S+E+ T QQ L + Q D+ N +L + E+++D L L++ + L D
Sbjct: 996 SKEKKALQETHQQTLDDLQAEEDKVN----ILTKAKTKLEQQVDDLEGSLEQEKKLRMDL 1051
Query: 541 DGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ ++ L ++ E+ + D K+ + E E+ + + ++ + E + +++
Sbjct: 1052 ERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKI 1111
Query: 721 E 723
+
Sbjct: 1112 K 1112
Score = 50.8 bits (116), Expect = 5e-06
Identities = 38/220 (17%), Positives = 101/220 (45%), Gaps = 1/220 (0%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
AT++ ++ + + E +A ++ Q +K+ +V +LQ ++ +V ++
Sbjct: 1693 ATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESR 1752
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA-Q 417
+ K ++A D ++L + A L R + +E+ ++ + R A+Q L+ +
Sbjct: 1753 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGK 1812
Query: 418 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 597
+ + + LE + +++R + L++ ++ +++E + + ++D ++
Sbjct: 1813 KQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVD 1872
Query: 598 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+ +VKS + E EE+ + + L+ E+A +R
Sbjct: 1873 KLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEER 1912
Score = 44.4 bits (100), Expect = 4e-04
Identities = 47/208 (22%), Positives = 99/208 (47%), Gaps = 22/208 (10%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
+Q+ D + + +++ EL+K QVE++ + LE+A LE +E ++ + E+
Sbjct: 1509 QQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLEL 1568
Query: 322 ----AALNRKVQQIEED---LEKSEERSGTAQQKLLEAQ-QSADENNRMCKVLENRAQQD 477
+ ++RK+ + +E+ L+++ R Q L+A+ +S ++ R+ K +E +
Sbjct: 1569 NQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEM 1628
Query: 478 EERM--------DQLTNQ------LKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 615
E ++ + L N LKE +L +DA +++ +LA VE + + +
Sbjct: 1629 EIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEI 1688
Query: 616 KSGDAKISELEEELKVVGNSLKSLEVSE 699
+ A + + E K+ L L+ SE
Sbjct: 1689 EELWATLEQTERSRKIAEQEL--LDASE 1714
Score = 44.0 bits (99), Expect = 6e-04
Identities = 47/213 (22%), Positives = 97/213 (45%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T+ + K+ +A++ +D E + K+ ++V +L+ L Q E+ L +
Sbjct: 991 TIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQ-EKKLRM 1049
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
+ LE+A + LE K A E+ + N K QQ++E LEK E K +E +Q+
Sbjct: 1050 D---LERAKRKLEGDLK--LAQESTMDMENDK-QQLDEKLEKKEFEISNLISK-IEDEQA 1102
Query: 424 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 603
+ L+ + ++ + R+++L +++ R A+ + ++SR+L + + LE A
Sbjct: 1103 VEIQ------LQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEA 1156
Query: 604 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 702
+ + E E + + L+ + E
Sbjct: 1157 GGATSAQVELNKKREAEFQKLRRDLEEATLQHE 1189
Score = 43.2 bits (97), Expect = 0.001
Identities = 32/141 (22%), Positives = 69/141 (48%), Gaps = 7/141 (4%)
Frame = +1
Query: 307 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
TE E+A + + Q+ +++L KSE + ++K++ + ++ + + EER
Sbjct: 848 TEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEER 907
Query: 487 MDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
+QL ++KE AE+ + + E++ K +EDE + + + ++++
Sbjct: 908 CEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 967
Query: 646 EEELKVVGNSLKSLEVSEEKA 708
E+E N +K+L +EE A
Sbjct: 968 EKEKHATENKVKNL--TEEMA 986
Score = 39.1 bits (87), Expect = 0.016
Identities = 37/188 (19%), Positives = 82/188 (43%), Gaps = 5/188 (2%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKL-AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAE 318
E+Q D + E+++E + E AQVE LNK + + K + E+ EA
Sbjct: 1136 EKQRSDLSRELEEISERLEEAGGATSAQVE----LNKKREAEFQKLRRDLEEATLQHEAM 1191
Query: 319 VAALNRK----VQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
VAAL +K + ++ E ++ + +++ E + D+ + + + E+
Sbjct: 1192 VAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKM 1251
Query: 487 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 666
L +Q+ E + E+ ++++ + A ++ E ++ DA +S+L +
Sbjct: 1252 CRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQAS 1311
Query: 667 GNSLKSLE 690
++ L+
Sbjct: 1312 TQQIEELK 1319
Score = 36.3 bits (80), Expect = 0.11
Identities = 50/225 (22%), Positives = 100/225 (44%), Gaps = 17/225 (7%)
Frame = +1
Query: 91 QAMKLEKDNAMDKADTCEQQA--RDANLRAEKVNEEVRELQKKLAQVEEDL---ILNKN- 252
Q +LEK + + CE QA +A E ++ +Q +L QV+ ++ I K+
Sbjct: 1525 QIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDE 1584
Query: 253 KLEQANKDLEEKEKQLTAT-EAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
+++Q ++ + + +T +AE+ + N R +++E DL + E + A + E+ +
Sbjct: 1585 EIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLR 1644
Query: 421 SADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLL---AEDADGKSDEVSRKLAF 579
+ + K L++ + E+ +QL + A LL E+ ++ R
Sbjct: 1645 NYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKI 1704
Query: 580 VEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
E EL A +RV+ + + L K + N + L+ E+ Q
Sbjct: 1705 AEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQ 1749
>X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain (1437
AA) protein.
Length = 1437
Score = 61.7 bits (143), Expect = 3e-09
Identities = 45/212 (21%), Positives = 107/212 (50%), Gaps = 5/212 (2%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T ++ + ++ E + + ++ E++A+ A A + EE+++ Q A +E +
Sbjct: 1229 TKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 1285
Query: 244 NKNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
KN LEQ KDL E ++ L + ++ L +V+++E ++E ++R+ A + L
Sbjct: 1286 KKN-LEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLR 1344
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
+ ++ E + + ++ +D+L ++K + AE+A+ +S+ K ++
Sbjct: 1345 KHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQH 1404
Query: 589 ELEVAEDRVKSGDAKISELEEELKVVGNSLKS 684
ELE AE+R ++++++L + + V + +
Sbjct: 1405 ELEEAEERADIAESQVNKLRVKSREVHTKISA 1436
Score = 56.8 bits (131), Expect = 7e-08
Identities = 56/229 (24%), Positives = 103/229 (44%), Gaps = 7/229 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+++ +A+ +Q+ + + D ++ + ++ + K N EV + + E
Sbjct: 823 EEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWR---TNTE 879
Query: 229 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 387
D I +LE+A K L +E E+ + A A+ A+L + Q+++ EDL ERS
Sbjct: 880 TDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSN 939
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
A L + Q++ D KVL Q+ EE +L KE+R L+ + +
Sbjct: 940 AACAALDKKQRNFD------KVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEE 993
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
L D+LE K+ +IS+L E++ G + LE +++ Q
Sbjct: 994 SL----DQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQ 1038
Score = 54.8 bits (126), Expect = 3e-07
Identities = 60/241 (24%), Positives = 117/241 (48%), Gaps = 16/241 (6%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQV 225
++K T+ K +Q ++ E D+ D + CEQ ++ ++ E +EV E ++ ++
Sbjct: 376 EEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKN-KIQLEAKIKEVTERAEEEEEI 434
Query: 226 EEDLILNKNKLE----QANKDLEEKE-------KQLTATEAEVAALNRKVQQIEEDLEK- 369
+L K KLE + KD+++ E K+ ATE +V L ++ ++E + K
Sbjct: 435 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKL 494
Query: 370 SEERSG---TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA 540
S+E+ T QQ L + Q D+ N +L + E+++D L L++ + L D
Sbjct: 495 SKEKKALQETHQQTLDDLQAEEDKVN----ILTKAKTKLEQQVDDLEGSLEQEKKLRMDL 550
Query: 541 DGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ RKL E +L++A++ + +L+E+L+ + +L +S+ + Q V
Sbjct: 551 ----ERAKRKL---EGDLKLAQESTMDNENDKQQLDEKLEKKEFEISNL-ISKIEDEQAV 602
Query: 721 E 723
E
Sbjct: 603 E 603
Score = 51.6 bits (118), Expect = 3e-06
Identities = 38/222 (17%), Positives = 102/222 (45%), Gaps = 1/222 (0%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
AT++ ++ + + E +A ++ Q +K+ +V +LQ ++ +V ++
Sbjct: 1193 ATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESR 1252
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA-Q 417
+ K ++A D ++L + A L R + +E+ ++ + R A+Q L+ +
Sbjct: 1253 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGK 1312
Query: 418 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 597
+ + + LE + +++R + L++ ++ +++E + + ++D ++
Sbjct: 1313 KQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVD 1372
Query: 598 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ +VKS + E EE+ + + L+ E+A +R +
Sbjct: 1373 KLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERAD 1414
Score = 44.4 bits (100), Expect = 4e-04
Identities = 47/208 (22%), Positives = 99/208 (47%), Gaps = 22/208 (10%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
+Q+ D + + +++ EL+K QVE++ + LE+A LE +E ++ + E+
Sbjct: 1009 QQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLEL 1068
Query: 322 ----AALNRKVQQIEED---LEKSEERSGTAQQKLLEAQ-QSADENNRMCKVLENRAQQD 477
+ ++RK+ + +E+ L+++ R Q L+A+ +S ++ R+ K +E +
Sbjct: 1069 NQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEM 1128
Query: 478 EERM--------DQLTNQ------LKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 615
E ++ + L N LKE +L +DA +++ +LA VE + + +
Sbjct: 1129 EIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEI 1188
Query: 616 KSGDAKISELEEELKVVGNSLKSLEVSE 699
+ A + + E K+ L L+ SE
Sbjct: 1189 EELWATLEQTERSRKIAEQEL--LDASE 1214
Score = 43.6 bits (98), Expect = 7e-04
Identities = 47/213 (22%), Positives = 97/213 (45%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T+ + K+ +A++ +D E + K+ ++V +L+ L Q E+ L +
Sbjct: 490 TIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQ-EKKLRM 548
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
+ LE+A + LE K A E+ + N K QQ++E LEK E K +E +Q+
Sbjct: 549 D---LERAKRKLEGDLK--LAQESTMDNENDK-QQLDEKLEKKEFEISNLISK-IEDEQA 601
Query: 424 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 603
+ L+ + ++ + R+++L +++ R A+ + ++SR+L + + LE A
Sbjct: 602 VEIQ------LQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEA 655
Query: 604 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 702
+ + E E + + L+ + E
Sbjct: 656 GGATSAQVELNKKREAEFQKLRRDLEEATLQHE 688
Score = 43.2 bits (97), Expect = 0.001
Identities = 32/141 (22%), Positives = 69/141 (48%), Gaps = 7/141 (4%)
Frame = +1
Query: 307 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
TE E+A + + Q+ +++L KSE + ++K++ + ++ + + EER
Sbjct: 347 TEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEER 406
Query: 487 MDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
+QL ++KE AE+ + + E++ K +EDE + + + ++++
Sbjct: 407 CEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 466
Query: 646 EEELKVVGNSLKSLEVSEEKA 708
E+E N +K+L +EE A
Sbjct: 467 EKEKHATENKVKNL--TEEMA 485
Score = 36.3 bits (80), Expect = 0.11
Identities = 36/189 (19%), Positives = 84/189 (44%), Gaps = 6/189 (3%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKL-AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAE 318
E+Q D + E+++E + E AQVE LNK + + K + E+ EA
Sbjct: 635 EKQRSDLSRELEEISERLEEAGGATSAQVE----LNKKREAEFQKLRRDLEEATLQHEAM 690
Query: 319 VAALNRK----VQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN-RAQQDEE 483
VAAL +K + ++ E ++ + +++ E + D+ + + + + +++
Sbjct: 691 VAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKD 750
Query: 484 RMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKV 663
L +Q+ E + E+ ++++ + A ++ E ++ DA +S+L +
Sbjct: 751 GGRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQA 810
Query: 664 VGNSLKSLE 690
++ L+
Sbjct: 811 STQQIEELK 819
Score = 36.3 bits (80), Expect = 0.11
Identities = 50/225 (22%), Positives = 100/225 (44%), Gaps = 17/225 (7%)
Frame = +1
Query: 91 QAMKLEKDNAMDKADTCEQQA--RDANLRAEKVNEEVRELQKKLAQVEEDL---ILNKN- 252
Q +LEK + + CE QA +A E ++ +Q +L QV+ ++ I K+
Sbjct: 1025 QIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDE 1084
Query: 253 KLEQANKDLEEKEKQLTAT-EAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
+++Q ++ + + +T +AE+ + N R +++E DL + E + A + E+ +
Sbjct: 1085 EIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLR 1144
Query: 421 SADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLL---AEDADGKSDEVSRKLAF 579
+ + K L++ + E+ +QL + A LL E+ ++ R
Sbjct: 1145 NYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKI 1204
Query: 580 VEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
E EL A +RV+ + + L K + N + L+ E+ Q
Sbjct: 1205 AEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQ 1249
>BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1,
skeletal muscle, adult protein.
Length = 1939
Score = 61.7 bits (143), Expect = 3e-09
Identities = 49/216 (22%), Positives = 112/216 (51%), Gaps = 7/216 (3%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T ++ + ++ E ++ + +A E++A+ A A + EE+++ Q A +E +
Sbjct: 1730 TKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 1786
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
KN LEQ KDL+ + + A + + +++Q++E + + E + Q++ +EA +
Sbjct: 1787 KKN-LEQTVKDLQHRLDE--AEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKG 1843
Query: 424 ADENNRMCKVLENRAQQD-------EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 582
++ R K L + ++D ++ +D+L ++K + AE+A+ +S+ K +
Sbjct: 1844 LRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRI 1903
Query: 583 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
+ ELE AE+R ++++++L + + V + S E
Sbjct: 1904 QHELEEAEERADIAESQVNKLRVKSREVHTKIISEE 1939
Score = 58.0 bits (134), Expect = 3e-08
Identities = 49/222 (22%), Positives = 108/222 (48%), Gaps = 9/222 (4%)
Frame = +1
Query: 76 IKKKMQA---MKLEKDNAMDKAD-TCEQQARDANLRAE--KVNEEVRELQKKLAQVEEDL 237
IK K+Q +K + A D+ + E A+ L E ++ +++ +L+ LA+VE++
Sbjct: 913 IKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 972
Query: 238 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 417
+NK++ +++ ++ + E AL QQ +DL+ E++ T + ++ +
Sbjct: 973 HATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLE 1032
Query: 418 QSADENNRMCKVLENRAQQDEERMD-QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 594
Q D+ + E + + D ER +L LK A+ D + ++ KL E E+
Sbjct: 1033 QQVDDLEGSLE-QEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEM 1091
Query: 595 EVAEDRVKSGDAKISELEEELKVVGNSLKSL--EVSEEKANQ 714
+ +++ A +L++++K + ++ L E+ E+A++
Sbjct: 1092 SGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASR 1133
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/226 (15%), Positives = 104/226 (46%), Gaps = 1/226 (0%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++ AT++ ++ + + E +A ++ Q +K+ ++ ++Q ++ +
Sbjct: 1690 EELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDII 1749
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
++ + K ++A D ++L + A L R + +E+ ++ + R A+Q L
Sbjct: 1750 QEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLAL 1809
Query: 409 EA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
+ ++ + + LE + +++R + L++ ++ +++E + + ++
Sbjct: 1810 KGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQ 1869
Query: 586 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
D ++ + +VKS + E EE+ V + + ++ E+A +R +
Sbjct: 1870 DLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERAD 1915
Score = 47.6 bits (108), Expect = 4e-05
Identities = 34/141 (24%), Positives = 69/141 (48%), Gaps = 7/141 (4%)
Frame = +1
Query: 307 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
TE E+A + + ++ +E+L K+E + ++K++ Q ++ + + EER
Sbjct: 849 TEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEER 908
Query: 487 MDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
DQL ++KE AED + + E++ K +EDE + + + ++++
Sbjct: 909 CDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 968
Query: 646 EEELKVVGNSLKSLEVSEEKA 708
E+E N +K+L +EE A
Sbjct: 969 EKEKHATENKVKNL--TEEMA 987
Score = 38.3 bits (85), Expect = 0.028
Identities = 48/225 (21%), Positives = 104/225 (46%), Gaps = 5/225 (2%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
+TMD K Q + K + + + + D ++ ++++ELQ ++ ++EE++
Sbjct: 1069 STMDIENDKQQLDEKLKKKEFEMSGL-QSKIEDEQALGMQLQKKIKELQARIEELEEEI- 1126
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
+ E+A++ EK++ + L+R++++I E LE E T+ Q + ++
Sbjct: 1127 ----EAERASRAKAEKQR---------SDLSRELEEISERLE--EAGGATSAQIEMNKKR 1171
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEA-RLLAEDADGKSDEVSRKLAFVEDELE 597
A E +M + LE Q E L + ++ L E D V +KL + E++
Sbjct: 1172 EA-EFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQID-NLQRVKQKLEKEKSEMK 1229
Query: 598 VAEDRVKSGDAKISE----LEEELKVVGNSLKSLEVSEEKANQRV 720
+ D + S +S+ LE+ + + + L ++ EE+ + +
Sbjct: 1230 MEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLI 1274
>AK093463-1|BAC04173.1| 650|Homo sapiens protein ( Homo sapiens
cDNA FLJ36144 fis, clone TESTI2025022, weakly similar to
TRICHOHYALIN. ).
Length = 650
Score = 61.7 bits (143), Expect = 3e-09
Identities = 41/174 (23%), Positives = 93/174 (53%), Gaps = 1/174 (0%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
E++ R+ + + E++ +K+L + E++L + +L + K L E+E+Q+ E ++
Sbjct: 299 EERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKK-LREQEEQMQEQEEKM 357
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA-DENNRMCKVLENRAQQDEERMDQL 498
K+++ EE + + EER ++++ E +Q D+ RM + + R ++ EERM +
Sbjct: 358 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ-DERLREKEERMREQ 416
Query: 499 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 660
++ + E+ K E +K E++++ E+R++ + K+ E EE ++
Sbjct: 417 EKMWEQVEKMREEK--KMQEQEKKTRDQEEKMQ-EEERIREREKKMREEEETMR 467
Score = 54.4 bits (125), Expect = 4e-07
Identities = 43/191 (22%), Positives = 98/191 (51%), Gaps = 2/191 (1%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL-QKKLAQVEEDLILNKN 252
++++ Q M+ +++ M + D ++ + EK+ E+V ++ ++K Q +E ++
Sbjct: 385 MREQEQKMR-DQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQE 443
Query: 253 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 432
+ Q + + E+EK++ E + K+Q+ EE++ + EE+ QQ+L E ++ E
Sbjct: 444 EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE-WQQQRLPEQKEKLWE 502
Query: 433 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR-KLAFVEDELEVAED 609
+M + E +Q+E+ DQ +E ++ E+ +E+ R K + D+ E ++
Sbjct: 503 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWQEEKMWGQEEMMREKEERIRDQKEKMQE 562
Query: 610 RVKSGDAKISE 642
R+ + + SE
Sbjct: 563 RLPEHEERCSE 573
Score = 53.6 bits (123), Expect = 7e-07
Identities = 42/234 (17%), Positives = 111/234 (47%), Gaps = 9/234 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNA--MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 222
++ A +++ + + +L+K NA +K E + + L +++ ++ + L Q
Sbjct: 205 ERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQ 264
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 402
V+ + + + ++ + ++L E+EK++ E ++ ++++ E + + EE+ +++
Sbjct: 265 VQTNTL--QEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKR 322
Query: 403 LLEAQQSADE------NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 564
L E ++ E + + E + Q+ EE+M + +++E + + E
Sbjct: 323 LREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 382
Query: 565 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVE 723
+++ E ++ E+R+ D ++ E EE ++ + +E + EEK Q E
Sbjct: 383 KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQE 436
Score = 49.6 bits (113), Expect = 1e-05
Identities = 44/227 (19%), Positives = 108/227 (47%), Gaps = 4/227 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE--KVNEEVRELQKKLAQ 222
Q+K ++ K ++Q E +++A Q + L+ E + EE+RE +KK+ +
Sbjct: 231 QEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRK 290
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 402
EE + + +L + + E+E+++ E + +++++ E++L + Q+K
Sbjct: 291 QEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELRE--------QKK 342
Query: 403 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL--KEARLLAEDADGKSDEVSRKLA 576
L E ++ E E + + EE+M + ++ +E RL ++ + E +K+
Sbjct: 343 LREQEEQMQEQ-------EEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE--QKMR 393
Query: 577 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
E+ + ++R++ + ++ E E+ + V + ++ E++ R
Sbjct: 394 DQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTR 440
Score = 48.0 bits (109), Expect = 3e-05
Identities = 42/197 (21%), Positives = 94/197 (47%), Gaps = 4/197 (2%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKV----NEEVRELQKKLAQVEEDLILN 246
K + Q K+ + + E + ++ LR +K E+++E ++K+ + EE +
Sbjct: 308 KMREQEEKMWRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQ 367
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+ K+ + + L E+EKQ+ E ++ ++ + +E L + EER Q+K+ E +
Sbjct: 368 EEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM-REQEKMWEQVEKM 426
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
E +M + E + + EE+M Q +++E + + E K+ E+ + E
Sbjct: 427 REEKKM-QEQEKKTRDQEEKM-QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 484
Query: 607 DRVKSGDAKISELEEEL 657
++ + ++ E +E+L
Sbjct: 485 EK-EWQQQRLPEQKEKL 500
>AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/d
protein.
Length = 1939
Score = 61.7 bits (143), Expect = 3e-09
Identities = 49/216 (22%), Positives = 112/216 (51%), Gaps = 7/216 (3%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T ++ + ++ E ++ + +A E++A+ A A + EE+++ Q A +E +
Sbjct: 1730 TKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 1786
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
KN LEQ KDL+ + + A + + +++Q++E + + E + Q++ +EA +
Sbjct: 1787 KKN-LEQTVKDLQHRLDE--AEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKG 1843
Query: 424 ADENNRMCKVLENRAQQD-------EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 582
++ R K L + ++D ++ +D+L ++K + AE+A+ +S+ K +
Sbjct: 1844 LRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRI 1903
Query: 583 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
+ ELE AE+R ++++++L + + V + S E
Sbjct: 1904 QHELEEAEERADIAESQVNKLRVKSREVHTKIISEE 1939
Score = 59.7 bits (138), Expect = 1e-08
Identities = 50/222 (22%), Positives = 109/222 (49%), Gaps = 9/222 (4%)
Frame = +1
Query: 76 IKKKMQA---MKLEKDNAMDKAD-TCEQQARDANLRAE--KVNEEVRELQKKLAQVEEDL 237
IK K+Q +K + A D+ + E A+ L E ++ +++ +L+ LA+VE++
Sbjct: 913 IKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 972
Query: 238 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 417
+NK++ +++ ++ + E AL QQ +DL+ E++ T + ++ +
Sbjct: 973 HATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLE 1032
Query: 418 QSADENNRMCKVLENRAQQDEERMD-QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 594
Q D+ + E + + D ER +L LK A+ A D + ++ KL E E+
Sbjct: 1033 QQVDDLEGSLE-QEKKIRMDLERAKRKLEGDLKLAQESAMDIENDKQQLDEKLKKKEFEM 1091
Query: 595 EVAEDRVKSGDAKISELEEELKVVGNSLKSL--EVSEEKANQ 714
+ +++ A +L++++K + ++ L E+ E+A++
Sbjct: 1092 SGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASR 1133
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/226 (15%), Positives = 104/226 (46%), Gaps = 1/226 (0%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++ AT++ ++ + + E +A ++ Q +K+ ++ ++Q ++ +
Sbjct: 1690 EELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDII 1749
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
++ + K ++A D ++L + A L R + +E+ ++ + R A+Q L
Sbjct: 1750 QEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLAL 1809
Query: 409 EA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
+ ++ + + LE + +++R + L++ ++ +++E + + ++
Sbjct: 1810 KGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQ 1869
Query: 586 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
D ++ + +VKS + E EE+ V + + ++ E+A +R +
Sbjct: 1870 DLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERAD 1915
Score = 47.6 bits (108), Expect = 4e-05
Identities = 34/141 (24%), Positives = 69/141 (48%), Gaps = 7/141 (4%)
Frame = +1
Query: 307 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
TE E+A + + ++ +E+L K+E + ++K++ Q ++ + + EER
Sbjct: 849 TEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEER 908
Query: 487 MDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
DQL ++KE AED + + E++ K +EDE + + + ++++
Sbjct: 909 CDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 968
Query: 646 EEELKVVGNSLKSLEVSEEKA 708
E+E N +K+L +EE A
Sbjct: 969 EKEKHATENKVKNL--TEEMA 987
Score = 36.3 bits (80), Expect = 0.11
Identities = 47/225 (20%), Positives = 103/225 (45%), Gaps = 5/225 (2%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
+ MD K Q + K + + + + D ++ ++++ELQ ++ ++EE++
Sbjct: 1069 SAMDIENDKQQLDEKLKKKEFEMSGL-QSKIEDEQALGMQLQKKIKELQARIEELEEEI- 1126
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
+ E+A++ EK++ + L+R++++I E LE E T+ Q + ++
Sbjct: 1127 ----EAERASRAKAEKQR---------SDLSRELEEISERLE--EAGGATSAQIEMNKKR 1171
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEA-RLLAEDADGKSDEVSRKLAFVEDELE 597
A E +M + LE Q E L + ++ L E D V +KL + E++
Sbjct: 1172 EA-EFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQID-NLQRVKQKLEKEKSEMK 1229
Query: 598 VAEDRVKSGDAKISE----LEEELKVVGNSLKSLEVSEEKANQRV 720
+ D + S +S+ LE+ + + + L ++ EE+ + +
Sbjct: 1230 MEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLI 1274
>X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein.
Length = 2185
Score = 61.3 bits (142), Expect = 3e-09
Identities = 53/223 (23%), Positives = 111/223 (49%), Gaps = 11/223 (4%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAMDKADT-CEQQARDANLRAEKVN---EEVRELQKKLAQVEEDLILN 246
KKK Q+ + N + + E ++++A + E++N EE+ + K+ ++ ++ +
Sbjct: 1446 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDD 1505
Query: 247 KNKLEQANKDLEEKEKQLTAT----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 414
K+K+E+ +LE + K TA E + +++ + E L+ ++ ++L++
Sbjct: 1506 KSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQK 1565
Query: 415 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 594
Q E + + +NR ++ EE++ L NQ+ + E + + V+ + E+EL
Sbjct: 1566 LQHFQE---LGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEEL 1622
Query: 595 EVAEDRVKS-GDAKISELEE--ELKVVGNSLKSLEVSEEKANQ 714
+ EDR++S AK++EL+ E K+ + L EEK Q
Sbjct: 1623 KALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQ 1665
Score = 50.0 bits (114), Expect = 8e-06
Identities = 49/228 (21%), Positives = 98/228 (42%), Gaps = 3/228 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ-- 222
Q + I+ Q + ++D+ + E + ++ + EKV ++ +E+Q+ L +
Sbjct: 915 QMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKL 974
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 402
++++ L K +LE +L +KEKQ A E+A N I + + + E +
Sbjct: 975 LDQEAKL-KKELENTALELSQKEKQFNAKMLEMAQANS--AGISDAVSRLETNQKEQIES 1031
Query: 403 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTN-QLKEARLLAEDADGKSDEVSRKLAF 579
L E + E N + + E + Q E + ++ QL+E + K +
Sbjct: 1032 LTEVHRR--ELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEE 1089
Query: 580 VEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ E+ ++ D ++EL+E+LK + SL E K +E
Sbjct: 1090 MNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLE 1137
Score = 47.6 bits (108), Expect = 4e-05
Identities = 50/226 (22%), Positives = 101/226 (44%), Gaps = 1/226 (0%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+ A + +K+ A LE A + A + +R + E++ E + E+ ++ ++
Sbjct: 986 ENTALELSQKEKQFNAKMLEMAQA-NSAGISDAVSRLETNQKEQI-ESLTEVHRR--ELN 1041
Query: 229 EDLILNKNKLEQANKDLEE-KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
+ + + + KL Q ++L+E E QL E EVA L +K+ EK E K
Sbjct: 1042 DVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLF--GCEKEEMNKEITWLKE 1099
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
+Q N L+ + +Q ++ L + + E + ++ ++ F++
Sbjct: 1100 EGVKQDTTLNE-----LQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQ 1154
Query: 586 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
++L + + K+SEL +LK +SL+ S EK+N+ +E
Sbjct: 1155 EQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLE 1200
Score = 42.7 bits (96), Expect = 0.001
Identities = 55/218 (25%), Positives = 98/218 (44%), Gaps = 2/218 (0%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKD-NAMDKADT-CEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
D K K KLE D N K +T ++Q + + AE+ +V EL KL +E+
Sbjct: 1128 DETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQS 1187
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
K+ E++NK LE+K + E+A Q++ +K+E LLEA+ +
Sbjct: 1188 LKSSHEKSNKSLEDKSLEFKKLSEELAI------QLDICCKKTE--------ALLEAKTN 1233
Query: 424 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 603
N K N T ++KEA L+ + + R+L ++ L ++
Sbjct: 1234 ELINISSSKT--NAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNIS 1291
Query: 604 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+ ++ E E ++K + ++SL V+E++A Q+
Sbjct: 1292 ---FQQATHQLEEKENQIKSMKADIESL-VTEKEALQK 1325
Score = 41.9 bits (94), Expect = 0.002
Identities = 29/147 (19%), Positives = 72/147 (48%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
+ +K Q +++ ++KA E + +++ EE +L KK+A+ ++DL K
Sbjct: 2005 LAQKEQELEMTIKETINKAQEVEAELLESH------QEETNQLLKKIAEKDDDL---KRT 2055
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
++ + L+ +E+++TA ++ ++Q+ + + EE G ++E Q +
Sbjct: 2056 AKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQK 2115
Query: 436 NRMCKVLENRAQQDEERMDQLTNQLKE 516
+ + + Q+ E++ L ++LK+
Sbjct: 2116 TTLISDSKLKEQEFREQIHNLEDRLKK 2142
Score = 40.3 bits (90), Expect = 0.007
Identities = 43/217 (19%), Positives = 97/217 (44%), Gaps = 3/217 (1%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKA---DTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
+ + + A+ L K+ +K + +Q D N++ + + + E + ++ + +
Sbjct: 1348 LSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQN-SISLSEKEAAISSLRKQYDEE 1406
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
K +L +DL K T ++ +++AL +Q+++ K E AQ + + Q +
Sbjct: 1407 KCELLDQVQDLSFKVD--TLSKEKISAL----EQVDDWSNKFSEWKKKAQSRFTQHQNTV 1460
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
E ++ A + +E+++ L +L + + G+ ++ K+ E LE
Sbjct: 1461 KELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLET-- 1518
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+KS A+I ELE+ + ++SL + NQ+
Sbjct: 1519 -ELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQ 1554
>U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein.
Length = 2230
Score = 61.3 bits (142), Expect = 3e-09
Identities = 53/223 (23%), Positives = 111/223 (49%), Gaps = 11/223 (4%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAMDKADT-CEQQARDANLRAEKVN---EEVRELQKKLAQVEEDLILN 246
KKK Q+ + N + + E ++++A + E++N EE+ + K+ ++ ++ +
Sbjct: 1446 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDD 1505
Query: 247 KNKLEQANKDLEEKEKQLTAT----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 414
K+K+E+ +LE + K TA E + +++ + E L+ ++ ++L++
Sbjct: 1506 KSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQK 1565
Query: 415 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 594
Q E + + +NR ++ EE++ L NQ+ + E + + V+ + E+EL
Sbjct: 1566 LQHFQE---LGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEEL 1622
Query: 595 EVAEDRVKS-GDAKISELEE--ELKVVGNSLKSLEVSEEKANQ 714
+ EDR++S AK++EL+ E K+ + L EEK Q
Sbjct: 1623 KALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQ 1665
Score = 50.0 bits (114), Expect = 8e-06
Identities = 49/228 (21%), Positives = 98/228 (42%), Gaps = 3/228 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ-- 222
Q + I+ Q + ++D+ + E + ++ + EKV ++ +E+Q+ L +
Sbjct: 915 QMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKL 974
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 402
++++ L K +LE +L +KEKQ A E+A N I + + + E +
Sbjct: 975 LDQEAKL-KKELENTALELSQKEKQFNAKMLEMAQANS--AGISDAVSRLETNQKEQIES 1031
Query: 403 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTN-QLKEARLLAEDADGKSDEVSRKLAF 579
L E + E N + + E + Q E + ++ QL+E + K +
Sbjct: 1032 LTEVHRR--ELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEE 1089
Query: 580 VEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ E+ ++ D ++EL+E+LK + SL E K +E
Sbjct: 1090 MNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLE 1137
Score = 47.6 bits (108), Expect = 4e-05
Identities = 50/226 (22%), Positives = 101/226 (44%), Gaps = 1/226 (0%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+ A + +K+ A LE A + A + +R + E++ E + E+ ++ ++
Sbjct: 986 ENTALELSQKEKQFNAKMLEMAQA-NSAGISDAVSRLETNQKEQI-ESLTEVHRR--ELN 1041
Query: 229 EDLILNKNKLEQANKDLEE-KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
+ + + + KL Q ++L+E E QL E EVA L +K+ EK E K
Sbjct: 1042 DVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLF--GCEKEEMNKEITWLKE 1099
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
+Q N L+ + +Q ++ L + + E + ++ ++ F++
Sbjct: 1100 EGVKQDTTLNE-----LQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQ 1154
Query: 586 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
++L + + K+SEL +LK +SL+ S EK+N+ +E
Sbjct: 1155 EQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLE 1200
Score = 42.7 bits (96), Expect = 0.001
Identities = 55/218 (25%), Positives = 98/218 (44%), Gaps = 2/218 (0%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKD-NAMDKADT-CEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
D K K KLE D N K +T ++Q + + AE+ +V EL KL +E+
Sbjct: 1128 DETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQS 1187
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
K+ E++NK LE+K + E+A Q++ +K+E LLEA+ +
Sbjct: 1188 LKSSHEKSNKSLEDKSLEFKKLSEELAI------QLDICCKKTE--------ALLEAKTN 1233
Query: 424 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 603
N K N T ++KEA L+ + + R+L ++ L ++
Sbjct: 1234 ELINISSSKT--NAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNIS 1291
Query: 604 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+ ++ E E ++K + ++SL V+E++A Q+
Sbjct: 1292 ---FQQATHQLEEKENQIKSMKADIESL-VTEKEALQK 1325
Score = 41.9 bits (94), Expect = 0.002
Identities = 29/147 (19%), Positives = 72/147 (48%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
+ +K Q +++ ++KA E + +++ EE +L KK+A+ ++DL K
Sbjct: 2005 LAQKEQELEMTIKETINKAQEVEAELLESH------QEETNQLLKKIAEKDDDL---KRT 2055
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
++ + L+ +E+++TA ++ ++Q+ + + EE G ++E Q +
Sbjct: 2056 AKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQK 2115
Query: 436 NRMCKVLENRAQQDEERMDQLTNQLKE 516
+ + + Q+ E++ L ++LK+
Sbjct: 2116 TTLISDSKLKEQEFREQIHNLEDRLKK 2142
Score = 40.3 bits (90), Expect = 0.007
Identities = 43/217 (19%), Positives = 97/217 (44%), Gaps = 3/217 (1%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKA---DTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
+ + + A+ L K+ +K + +Q D N++ + + + E + ++ + +
Sbjct: 1348 LSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQN-SISLSEKEAAISSLRKQYDEE 1406
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
K +L +DL K T ++ +++AL +Q+++ K E AQ + + Q +
Sbjct: 1407 KCELLDQVQDLSFKVD--TLSKEKISAL----EQVDDWSNKFSEWKKKAQSRFTQHQNTV 1460
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
E ++ A + +E+++ L +L + + G+ ++ K+ E LE
Sbjct: 1461 KELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLET-- 1518
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+KS A+I ELE+ + ++SL + NQ+
Sbjct: 1519 -ELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQ 1554
>U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein.
Length = 2083
Score = 61.3 bits (142), Expect = 3e-09
Identities = 53/223 (23%), Positives = 111/223 (49%), Gaps = 11/223 (4%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAMDKADT-CEQQARDANLRAEKVN---EEVRELQKKLAQVEEDLILN 246
KKK Q+ + N + + E ++++A + E++N EE+ + K+ ++ ++ +
Sbjct: 1301 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDD 1360
Query: 247 KNKLEQANKDLEEKEKQLTAT----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 414
K+K+E+ +LE + K TA E + +++ + E L+ ++ ++L++
Sbjct: 1361 KSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQK 1420
Query: 415 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 594
Q E + + +NR ++ EE++ L NQ+ + E + + V+ + E+EL
Sbjct: 1421 LQHFQE---LGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEEL 1477
Query: 595 EVAEDRVKS-GDAKISELEE--ELKVVGNSLKSLEVSEEKANQ 714
+ EDR++S AK++EL+ E K+ + L EEK Q
Sbjct: 1478 KALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQ 1520
Score = 50.0 bits (114), Expect = 8e-06
Identities = 49/228 (21%), Positives = 98/228 (42%), Gaps = 3/228 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ-- 222
Q + I+ Q + ++D+ + E + ++ + EKV ++ +E+Q+ L +
Sbjct: 770 QMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKL 829
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 402
++++ L K +LE +L +KEKQ A E+A N I + + + E +
Sbjct: 830 LDQEAKL-KKELENTALELSQKEKQFNAKMLEMAQANS--AGISDAVSRLETNQKEQIES 886
Query: 403 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTN-QLKEARLLAEDADGKSDEVSRKLAF 579
L E + E N + + E + Q E + ++ QL+E + K +
Sbjct: 887 LTEVHRR--ELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEE 944
Query: 580 VEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ E+ ++ D ++EL+E+LK + SL E K +E
Sbjct: 945 MNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLE 992
Score = 47.6 bits (108), Expect = 4e-05
Identities = 50/226 (22%), Positives = 101/226 (44%), Gaps = 1/226 (0%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+ A + +K+ A LE A + A + +R + E++ E + E+ ++ ++
Sbjct: 841 ENTALELSQKEKQFNAKMLEMAQA-NSAGISDAVSRLETNQKEQI-ESLTEVHRR--ELN 896
Query: 229 EDLILNKNKLEQANKDLEE-KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
+ + + + KL Q ++L+E E QL E EVA L +K+ EK E K
Sbjct: 897 DVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLF--GCEKEEMNKEITWLKE 954
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
+Q N L+ + +Q ++ L + + E + ++ ++ F++
Sbjct: 955 EGVKQDTTLNE-----LQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQ 1009
Query: 586 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
++L + + K+SEL +LK +SL+ S EK+N+ +E
Sbjct: 1010 EQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLE 1055
Score = 42.7 bits (96), Expect = 0.001
Identities = 55/218 (25%), Positives = 98/218 (44%), Gaps = 2/218 (0%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKD-NAMDKADT-CEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
D K K KLE D N K +T ++Q + + AE+ +V EL KL +E+
Sbjct: 983 DETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQS 1042
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
K+ E++NK LE+K + E+A Q++ +K+E LLEA+ +
Sbjct: 1043 LKSSHEKSNKSLEDKSLEFKKLSEELAI------QLDICCKKTE--------ALLEAKTN 1088
Query: 424 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 603
N K N T ++KEA L+ + + R+L ++ L ++
Sbjct: 1089 ELINISSSKT--NAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNIS 1146
Query: 604 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+ ++ E E ++K + ++SL V+E++A Q+
Sbjct: 1147 ---FQQATHQLEEKENQIKSMKADIESL-VTEKEALQK 1180
Score = 41.9 bits (94), Expect = 0.002
Identities = 29/147 (19%), Positives = 72/147 (48%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
+ +K Q +++ ++KA E + +++ EE +L KK+A+ ++DL K
Sbjct: 1860 LAQKEQELEMTIKETINKAQEVEAELLESH------QEETNQLLKKIAEKDDDL---KRT 1910
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
++ + L+ +E+++TA ++ ++Q+ + + EE G ++E Q +
Sbjct: 1911 AKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQK 1970
Query: 436 NRMCKVLENRAQQDEERMDQLTNQLKE 516
+ + + Q+ E++ L ++LK+
Sbjct: 1971 TTLISDSKLKEQEFREQIHNLEDRLKK 1997
Score = 40.3 bits (90), Expect = 0.007
Identities = 43/217 (19%), Positives = 97/217 (44%), Gaps = 3/217 (1%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKA---DTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
+ + + A+ L K+ +K + +Q D N++ + + + E + ++ + +
Sbjct: 1203 LSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQN-SISLSEKEAAISSLRKQYDEE 1261
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
K +L +DL K T ++ +++AL +Q+++ K E AQ + + Q +
Sbjct: 1262 KCELLDQVQDLSFKVD--TLSKEKISAL----EQVDDWSNKFSEWKKKAQSRFTQHQNTV 1315
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
E ++ A + +E+++ L +L + + G+ ++ K+ E LE
Sbjct: 1316 KELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLET-- 1373
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+KS A+I ELE+ + ++SL + NQ+
Sbjct: 1374 -ELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQ 1409
>X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy chain
(1085 AA) protein.
Length = 1085
Score = 60.9 bits (141), Expect = 5e-09
Identities = 48/218 (22%), Positives = 109/218 (50%), Gaps = 5/218 (2%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T ++ + ++ E ++A A E++A+ A A + EE+++ Q A +E +
Sbjct: 872 TKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 928
Query: 244 NKNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
KN LEQ KDL E ++ L + ++ L +++++E +LE ++++ + + L
Sbjct: 929 KKN-LEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLR 987
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
+ ++ E + + ++ +D+L ++K + AE+AD +++ K +
Sbjct: 988 KYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQH 1047
Query: 589 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 702
ELE AE+R ++++++L + + +S + SEE
Sbjct: 1048 ELEEAEERADIAESQVNKLRAKTRDFTSSRMVVHESEE 1085
Score = 51.6 bits (118), Expect = 3e-06
Identities = 53/251 (21%), Positives = 116/251 (46%), Gaps = 26/251 (10%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQV 225
++K T+ K +Q ++ E +N +D + C+Q + A + E +EV E + ++
Sbjct: 20 EEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIK-AKFQLEAKIKEVTERAEDEEEI 78
Query: 226 EEDLILNKNKLE----QANKDLEEKE-------KQLTATEAEVAALNRKVQQIEEDLEK- 369
+L K KLE + KD+++ E K+ ATE +V L ++ ++E + K
Sbjct: 79 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKL 138
Query: 370 SEERSG--TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE--- 534
+ E+ A Q+ L+ Q+ ++ +++ +Q E ++ Q K+ R+ E
Sbjct: 139 TREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNK 198
Query: 535 -DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE---EELKVVG----NSLKSLE 690
+G + +E++ + ++R+K D + +L+ E+ + +G +K L+
Sbjct: 199 RKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQ 258
Query: 691 VSEEKANQRVE 723
E+ + +E
Sbjct: 259 ARIEELEEEIE 269
Score = 51.6 bits (118), Expect = 3e-06
Identities = 48/209 (22%), Positives = 99/209 (47%), Gaps = 15/209 (7%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
EQ+ D + + + + EL+K Q+E + + LE+A LE +E ++ + E+
Sbjct: 652 EQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLEL 711
Query: 322 ----AALNRKVQQIEEDLE---KSEERSGTAQQKLLEAQ-QSADENNRMCKVLENRAQQD 477
+ ++RK+ + +E++E ++ +R+ Q L+A+ + A+E R+ K +E +
Sbjct: 712 TQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRRANEAIRLKKKMEGDLNEI 771
Query: 478 EERMDQLTNQ----LKEARLL---AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 636
E ++ Q LK R + +D D+ R ++++L + E R A++
Sbjct: 772 EIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEV 831
Query: 637 SELEEELKVVGNSLKSLEVSEEKANQRVE 723
EL L+ + K E +N+RV+
Sbjct: 832 EELRATLEQTERARKLAEQELLDSNERVQ 860
Score = 51.2 bits (117), Expect = 4e-06
Identities = 38/216 (17%), Positives = 98/216 (45%), Gaps = 1/216 (0%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
+D + M+++ K N T E Q +A + E++ + EL + ++++ +
Sbjct: 374 IDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEA--- 430
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+ ++ LEEKE ++ A ++ ++++ LE+ + L ++
Sbjct: 431 ----GELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALGHALQSSRHDC 486
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE-DADGKSDEVSRKLAFVEDELEVA 603
D + + + + + + +++ + R E DA +++E+ + L+ +
Sbjct: 487 DLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDS 546
Query: 604 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
E++V++ +AK + LE+ + + ++ L V E+AN
Sbjct: 547 EEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERAN 582
Score = 50.0 bits (114), Expect = 8e-06
Identities = 46/219 (21%), Positives = 101/219 (46%), Gaps = 3/219 (1%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++K+ KLE D+ ++ + + + +++ E + K +++ L +
Sbjct: 363 LEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQ 422
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQ---QIEEDLEKSEERSGTAQQKLLEAQQSA 426
+ + E +QL E+ V+ L+R Q Q E+L++ E A+ L A QS+
Sbjct: 423 KSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALGHALQSS 482
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
+ C +L + ++++E +L L +A +E A ++ + + E ELE A+
Sbjct: 483 RHD---CDLLREQYEEEQEGKAELQRALSKAN--SEVAQWRTKYETDAIQRTE-ELEEAK 536
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
++ ++ + EE+++ V SLE ++++ VE
Sbjct: 537 KKLAQ---RLQDSEEQVEAVNAKCASLEKTKQRLQGEVE 572
Score = 49.6 bits (113), Expect = 1e-05
Identities = 53/233 (22%), Positives = 109/233 (46%), Gaps = 14/233 (6%)
Frame = +1
Query: 52 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 231
++A + I ++ A K + + D+ ++ D L KV +E + K+ + E
Sbjct: 70 ERAEDEEEINAELTAKKRKLE---DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTE 126
Query: 232 DLI-LNKN--KLEQANKDLEEKEKQ----LTATEAEVAALNR---KVQQIEEDLEKSEER 381
+L L++ KL + K L+E +Q L A E +V +LN+ K++Q EDLE S E+
Sbjct: 127 ELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQ 186
Query: 382 SGTAQQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGK 549
+ L ++ + + ++ + LEN QQ +ER+ + + + + ED
Sbjct: 187 EKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTL 246
Query: 550 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
+ +K+ ++ +E E+ +++ A ++ E++ L+ L E+A
Sbjct: 247 GLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEA 299
Score = 45.6 bits (103), Expect = 2e-04
Identities = 49/240 (20%), Positives = 112/240 (46%), Gaps = 15/240 (6%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+++A + A ++++A + + A A EQ+ D+N R + ++ + L ++E
Sbjct: 821 ERRANLLQAEVEELRATLEQTERARKLA---EQELLDSNERVQLLHTQNTSLIHTKKKLE 877
Query: 229 EDLILNKNKLEQANKD---LEEKEKQLTATEAEVAALNRKVQQIEEDLEKS----EERSG 387
DL+ ++++E A++D EEK K+ A +A +K Q LE+ E+
Sbjct: 878 TDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVK 937
Query: 388 TAQQKLLEAQQSA-DENNRMCKVLENRAQQ-------DEERMDQLTNQLKEARLLAEDAD 543
Q +L EA+Q A + + LE R ++ ++++ + L++ ++
Sbjct: 938 DLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELT 997
Query: 544 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+S+E + + ++D ++ + +VKS + E +E+ + + E+A +R +
Sbjct: 998 YQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERAD 1057
Score = 40.7 bits (91), Expect = 0.005
Identities = 29/122 (23%), Positives = 57/122 (46%), Gaps = 7/122 (5%)
Frame = +1
Query: 343 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN------ 504
Q+ +++L KSE + ++KL+ Q ++ + EER DQL
Sbjct: 3 QKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLE 62
Query: 505 -QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 681
++KE AED + + E++ K +EDE + + + ++++E+E N +K
Sbjct: 63 AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 122
Query: 682 SL 687
+L
Sbjct: 123 NL 124
>X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mRNA
for embryonic myosin heavy chain (SMHCE). ).
Length = 1085
Score = 60.9 bits (141), Expect = 5e-09
Identities = 48/218 (22%), Positives = 109/218 (50%), Gaps = 5/218 (2%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T ++ + ++ E ++A A E++A+ A A + EE+++ Q A +E +
Sbjct: 872 TKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 928
Query: 244 NKNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
KN LEQ KDL E ++ L + ++ L +++++E +LE ++++ + + L
Sbjct: 929 KKN-LEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLR 987
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
+ ++ E + + ++ +D+L ++K + AE+AD +++ K +
Sbjct: 988 KYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQH 1047
Query: 589 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 702
ELE AE+R ++++++L + + +S + SEE
Sbjct: 1048 ELEEAEERADIAESQVNKLRAKTRDFTSSRMVVHESEE 1085
Score = 52.0 bits (119), Expect = 2e-06
Identities = 46/223 (20%), Positives = 107/223 (47%), Gaps = 8/223 (3%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
+D + M+++ K N T E Q +A + E++ + EL + ++++ +
Sbjct: 374 IDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEA--- 430
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+ ++ LEEKE ++ A ++ ++++ LE+ + A+ L A QS+
Sbjct: 431 ----GELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENK----AKNALAHALQSS 482
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRKLAFV 582
+ C +L + ++++E +L L +A +A+ DA +++E+ +
Sbjct: 483 RHD---CDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 539
Query: 583 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
L+ +E++V++ +AK + LE+ + + ++ L V E+AN
Sbjct: 540 AQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERAN 582
Score = 51.6 bits (118), Expect = 3e-06
Identities = 53/251 (21%), Positives = 116/251 (46%), Gaps = 26/251 (10%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQV 225
++K T+ K +Q ++ E +N +D + C+Q + A + E +EV E + ++
Sbjct: 20 EEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIK-AKFQLEAKIKEVTERAEDEEEI 78
Query: 226 EEDLILNKNKLE----QANKDLEEKE-------KQLTATEAEVAALNRKVQQIEEDLEK- 369
+L K KLE + KD+++ E K+ ATE +V L ++ ++E + K
Sbjct: 79 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKL 138
Query: 370 SEERSG--TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE--- 534
+ E+ A Q+ L+ Q+ ++ +++ +Q E ++ Q K+ R+ E
Sbjct: 139 TREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNK 198
Query: 535 -DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE---EELKVVG----NSLKSLE 690
+G + +E++ + ++R+K D + +L+ E+ + +G +K L+
Sbjct: 199 RKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQ 258
Query: 691 VSEEKANQRVE 723
E+ + +E
Sbjct: 259 ARIEELEEEIE 269
Score = 51.6 bits (118), Expect = 3e-06
Identities = 48/209 (22%), Positives = 99/209 (47%), Gaps = 15/209 (7%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
EQ+ D + + + + EL+K Q+E + + LE+A LE +E ++ + E+
Sbjct: 652 EQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLEL 711
Query: 322 ----AALNRKVQQIEEDLE---KSEERSGTAQQKLLEAQ-QSADENNRMCKVLENRAQQD 477
+ ++RK+ + +E++E ++ +R+ Q L+A+ +S +E R+ K +E +
Sbjct: 712 TQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEI 771
Query: 478 EERMDQLTNQ----LKEARLL---AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 636
E ++ Q LK R + +D D+ R ++++L + E R A++
Sbjct: 772 EIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEV 831
Query: 637 SELEEELKVVGNSLKSLEVSEEKANQRVE 723
EL L+ + K E +N+RV+
Sbjct: 832 EELRATLEQTERARKLAEQELLDSNERVQ 860
Score = 51.2 bits (117), Expect = 4e-06
Identities = 46/219 (21%), Positives = 101/219 (46%), Gaps = 3/219 (1%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++K+ KLE D+ ++ + + + +++ E + K +++ L +
Sbjct: 363 LEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQ 422
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQ---QIEEDLEKSEERSGTAQQKLLEAQQSA 426
+ + E +QL E+ V+ L+R Q Q E+L++ E A+ L A QS+
Sbjct: 423 KSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSS 482
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
+ C +L + ++++E +L L +A +E A ++ + + E ELE A+
Sbjct: 483 RHD---CDLLREQYEEEQEGKAELQRALSKAN--SEVAQWRTKYETDAIQRTE-ELEEAK 536
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
++ ++ + EE+++ V SLE ++++ VE
Sbjct: 537 KKLAQ---RLQDSEEQVEAVNAKCASLEKTKQRLQGEVE 572
Score = 49.6 bits (113), Expect = 1e-05
Identities = 53/233 (22%), Positives = 109/233 (46%), Gaps = 14/233 (6%)
Frame = +1
Query: 52 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 231
++A + I ++ A K + + D+ ++ D L KV +E + K+ + E
Sbjct: 70 ERAEDEEEINAELTAKKRKLE---DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTE 126
Query: 232 DLI-LNKN--KLEQANKDLEEKEKQ----LTATEAEVAALNR---KVQQIEEDLEKSEER 381
+L L++ KL + K L+E +Q L A E +V +LN+ K++Q EDLE S E+
Sbjct: 127 ELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQ 186
Query: 382 SGTAQQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGK 549
+ L ++ + + ++ + LEN QQ +ER+ + + + + ED
Sbjct: 187 EKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTL 246
Query: 550 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
+ +K+ ++ +E E+ +++ A ++ E++ L+ L E+A
Sbjct: 247 GLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEA 299
Score = 45.6 bits (103), Expect = 2e-04
Identities = 49/240 (20%), Positives = 112/240 (46%), Gaps = 15/240 (6%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+++A + A ++++A + + A A EQ+ D+N R + ++ + L ++E
Sbjct: 821 ERRANLLQAEVEELRATLEQTERARKLA---EQELLDSNERVQLLHTQNTSLIHTKKKLE 877
Query: 229 EDLILNKNKLEQANKD---LEEKEKQLTATEAEVAALNRKVQQIEEDLEKS----EERSG 387
DL+ ++++E A++D EEK K+ A +A +K Q LE+ E+
Sbjct: 878 TDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVK 937
Query: 388 TAQQKLLEAQQSA-DENNRMCKVLENRAQQ-------DEERMDQLTNQLKEARLLAEDAD 543
Q +L EA+Q A + + LE R ++ ++++ + L++ ++
Sbjct: 938 DLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELT 997
Query: 544 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+S+E + + ++D ++ + +VKS + E +E+ + + E+A +R +
Sbjct: 998 YQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERAD 1057
Score = 40.7 bits (91), Expect = 0.005
Identities = 29/122 (23%), Positives = 57/122 (46%), Gaps = 7/122 (5%)
Frame = +1
Query: 343 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN------ 504
Q+ +++L KSE + ++KL+ Q ++ + EER DQL
Sbjct: 3 QKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLE 62
Query: 505 -QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 681
++KE AED + + E++ K +EDE + + + ++++E+E N +K
Sbjct: 63 AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 122
Query: 682 SL 687
+L
Sbjct: 123 NL 124
>X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for
embryonic myosin heavy chain. ).
Length = 1940
Score = 60.9 bits (141), Expect = 5e-09
Identities = 48/218 (22%), Positives = 109/218 (50%), Gaps = 5/218 (2%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T ++ + ++ E ++A A E++A+ A A + EE+++ Q A +E +
Sbjct: 1727 TKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 1783
Query: 244 NKNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
KN LEQ KDL E ++ L + ++ L +++++E +LE ++++ + + L
Sbjct: 1784 KKN-LEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLR 1842
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
+ ++ E + + ++ +D+L ++K + AE+AD +++ K +
Sbjct: 1843 KYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQH 1902
Query: 589 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 702
ELE AE+R ++++++L + + +S + SEE
Sbjct: 1903 ELEEAEERADIAESQVNKLRAKTRDFTSSRMVVHESEE 1940
Score = 52.0 bits (119), Expect = 2e-06
Identities = 46/223 (20%), Positives = 107/223 (47%), Gaps = 8/223 (3%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
+D + M+++ K N T E Q +A + E++ + EL + ++++ +
Sbjct: 1229 IDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEA--- 1285
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+ ++ LEEKE ++ A ++ ++++ LE+ + A+ L A QS+
Sbjct: 1286 ----GELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENK----AKNALAHALQSS 1337
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRKLAFV 582
+ C +L + ++++E +L L +A +A+ DA +++E+ +
Sbjct: 1338 RHD---CDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAQEKL 1394
Query: 583 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
L+ +E++V++ +AK + LE+ + + ++ L V E+AN
Sbjct: 1395 AQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERAN 1437
Score = 51.6 bits (118), Expect = 3e-06
Identities = 53/251 (21%), Positives = 116/251 (46%), Gaps = 26/251 (10%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQV 225
++K T+ K +Q ++ E +N +D + C+Q + A + E +EV E + ++
Sbjct: 875 EEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIK-AKFQLEAKIKEVTERAEDEEEI 933
Query: 226 EEDLILNKNKLE----QANKDLEEKE-------KQLTATEAEVAALNRKVQQIEEDLEK- 369
+L K KLE + KD+++ E K+ ATE +V L ++ ++E + K
Sbjct: 934 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKL 993
Query: 370 SEERSG--TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE--- 534
+ E+ A Q+ L+ Q+ ++ +++ +Q E ++ Q K+ R+ E
Sbjct: 994 TREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNK 1053
Query: 535 -DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE---EELKVVG----NSLKSLE 690
+G + +E++ + ++R+K D + +L+ E+ + +G +K L+
Sbjct: 1054 RKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQ 1113
Query: 691 VSEEKANQRVE 723
E+ + +E
Sbjct: 1114 ARIEELEEEIE 1124
Score = 51.6 bits (118), Expect = 3e-06
Identities = 48/209 (22%), Positives = 99/209 (47%), Gaps = 15/209 (7%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
EQ+ D + + + + EL+K Q+E + + LE+A LE +E ++ + E+
Sbjct: 1507 EQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLEL 1566
Query: 322 ----AALNRKVQQIEEDLE---KSEERSGTAQQKLLEAQ-QSADENNRMCKVLENRAQQD 477
+ ++RK+ + +E++E ++ +R+ Q L+A+ +S +E R+ K +E +
Sbjct: 1567 TQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEI 1626
Query: 478 EERMDQLTNQ----LKEARLL---AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 636
E ++ Q LK R + +D D+ R ++++L + E R A++
Sbjct: 1627 EIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEV 1686
Query: 637 SELEEELKVVGNSLKSLEVSEEKANQRVE 723
EL L+ + K E +N+RV+
Sbjct: 1687 EELRATLEQTERARKLAEQELLDSNERVQ 1715
Score = 49.6 bits (113), Expect = 1e-05
Identities = 53/233 (22%), Positives = 109/233 (46%), Gaps = 14/233 (6%)
Frame = +1
Query: 52 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 231
++A + I ++ A K + + D+ ++ D L KV +E + K+ + E
Sbjct: 925 ERAEDEEEINAELTAKKRKLE---DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTE 981
Query: 232 DLI-LNKN--KLEQANKDLEEKEKQ----LTATEAEVAALNR---KVQQIEEDLEKSEER 381
+L L++ KL + K L+E +Q L A E +V +LN+ K++Q EDLE S E+
Sbjct: 982 ELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQ 1041
Query: 382 SGTAQQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGK 549
+ L ++ + + ++ + LEN QQ +ER+ + + + + ED
Sbjct: 1042 EKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTL 1101
Query: 550 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
+ +K+ ++ +E E+ +++ A ++ E++ L+ L E+A
Sbjct: 1102 GLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEA 1154
Score = 49.2 bits (112), Expect = 1e-05
Identities = 33/134 (24%), Positives = 64/134 (47%), Gaps = 7/134 (5%)
Frame = +1
Query: 307 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
TE E+A + + Q+ +++L KSE + ++KL+ Q ++ + EER
Sbjct: 846 TEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEER 905
Query: 487 MDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
DQL ++KE AED + + E++ K +EDE + + + ++++
Sbjct: 906 CDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 965
Query: 646 EEELKVVGNSLKSL 687
E+E N +K+L
Sbjct: 966 EKEKHATENKVKNL 979
Score = 45.6 bits (103), Expect = 2e-04
Identities = 49/240 (20%), Positives = 112/240 (46%), Gaps = 15/240 (6%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+++A + A ++++A + + A A EQ+ D+N R + ++ + L ++E
Sbjct: 1676 ERRANLLQAEVEELRATLEQTERARKLA---EQELLDSNERVQLLHTQNTSLIHTKKKLE 1732
Query: 229 EDLILNKNKLEQANKD---LEEKEKQLTATEAEVAALNRKVQQIEEDLEKS----EERSG 387
DL+ ++++E A++D EEK K+ A +A +K Q LE+ E+
Sbjct: 1733 TDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVK 1792
Query: 388 TAQQKLLEAQQSA-DENNRMCKVLENRAQQ-------DEERMDQLTNQLKEARLLAEDAD 543
Q +L EA+Q A + + LE R ++ ++++ + L++ ++
Sbjct: 1793 DLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELT 1852
Query: 544 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+S+E + + ++D ++ + +VKS + E +E+ + + E+A +R +
Sbjct: 1853 YQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERAD 1912
>X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 AA)
protein.
Length = 1167
Score = 60.9 bits (141), Expect = 5e-09
Identities = 48/218 (22%), Positives = 109/218 (50%), Gaps = 5/218 (2%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T ++ + ++ E ++A A E++A+ A A + EE+++ Q A +E +
Sbjct: 954 TKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 1010
Query: 244 NKNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
KN LEQ KDL E ++ L + ++ L +++++E +LE ++++ + + L
Sbjct: 1011 KKN-LEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLR 1069
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
+ ++ E + + ++ +D+L ++K + AE+AD +++ K +
Sbjct: 1070 KYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQH 1129
Query: 589 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 702
ELE AE+R ++++++L + + +S + SEE
Sbjct: 1130 ELEEAEERADIAESQVNKLRAKTRDFTSSRMVVHESEE 1167
Score = 52.0 bits (119), Expect = 2e-06
Identities = 46/223 (20%), Positives = 107/223 (47%), Gaps = 8/223 (3%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
+D + M+++ K N T E Q +A + E++ + EL + ++++ +
Sbjct: 456 IDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEA--- 512
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+ ++ LEEKE ++ A ++ ++++ LE+ + A+ L A QS+
Sbjct: 513 ----GELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENK----AKNALAHALQSS 564
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRKLAFV 582
+ C +L + ++++E +L L +A +A+ DA +++E+ +
Sbjct: 565 RHD---CDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAQEKL 621
Query: 583 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
L+ +E++V++ +AK + LE+ + + ++ L V E+AN
Sbjct: 622 AQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERAN 664
Score = 51.6 bits (118), Expect = 3e-06
Identities = 53/251 (21%), Positives = 116/251 (46%), Gaps = 26/251 (10%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQV 225
++K T+ K +Q ++ E +N +D + C+Q + A + E +EV E + ++
Sbjct: 102 EEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIK-AKFQLEAKIKEVTERAEDEEEI 160
Query: 226 EEDLILNKNKLE----QANKDLEEKE-------KQLTATEAEVAALNRKVQQIEEDLEK- 369
+L K KLE + KD+++ E K+ ATE +V L ++ ++E + K
Sbjct: 161 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKL 220
Query: 370 SEERSG--TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE--- 534
+ E+ A Q+ L+ Q+ ++ +++ +Q E ++ Q K+ R+ E
Sbjct: 221 TREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNK 280
Query: 535 -DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE---EELKVVG----NSLKSLE 690
+G + +E++ + ++R+K D + +L+ E+ + +G +K L+
Sbjct: 281 RKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQ 340
Query: 691 VSEEKANQRVE 723
E+ + +E
Sbjct: 341 ARIEELEEEIE 351
Score = 50.4 bits (115), Expect = 6e-06
Identities = 47/209 (22%), Positives = 99/209 (47%), Gaps = 15/209 (7%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
EQ+ D + + + + EL+K Q+E + + LE+A LE +E ++ + E+
Sbjct: 734 EQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLEL 793
Query: 322 ----AALNRKVQQIEEDLE---KSEERSGTAQQKLLEAQ-QSADENNRMCKVLENRAQQD 477
+ ++RK+ + +E++E ++ +R+ Q L+A+ +S +E R+ K +E +
Sbjct: 794 TQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEI 853
Query: 478 EERMDQLTNQ----LKEARLL---AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 636
E ++ Q LK R + +D D+ + ++++L + E R A++
Sbjct: 854 EIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALQTQEDLKEQLAIVERRANLLQAEV 913
Query: 637 SELEEELKVVGNSLKSLEVSEEKANQRVE 723
EL L+ + K E +N+RV+
Sbjct: 914 EELRATLEQTERARKLAEQELLDSNERVQ 942
Score = 49.6 bits (113), Expect = 1e-05
Identities = 53/233 (22%), Positives = 109/233 (46%), Gaps = 14/233 (6%)
Frame = +1
Query: 52 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 231
++A + I ++ A K + + D+ ++ D L KV +E + K+ + E
Sbjct: 152 ERAEDEEEINAELTAKKRKLE---DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTE 208
Query: 232 DLI-LNKN--KLEQANKDLEEKEKQ----LTATEAEVAALNR---KVQQIEEDLEKSEER 381
+L L++ KL + K L+E +Q L A E +V +LN+ K++Q EDLE S E+
Sbjct: 209 ELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQ 268
Query: 382 SGTAQQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGK 549
+ L ++ + + ++ + LEN QQ +ER+ + + + + ED
Sbjct: 269 EKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTL 328
Query: 550 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
+ +K+ ++ +E E+ +++ A ++ E++ L+ L E+A
Sbjct: 329 GLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEA 381
Score = 49.2 bits (112), Expect = 1e-05
Identities = 33/134 (24%), Positives = 64/134 (47%), Gaps = 7/134 (5%)
Frame = +1
Query: 307 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
TE E+A + + Q+ +++L KSE + ++KL+ Q ++ + EER
Sbjct: 73 TEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEER 132
Query: 487 MDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
DQL ++KE AED + + E++ K +EDE + + + ++++
Sbjct: 133 CDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 192
Query: 646 EEELKVVGNSLKSL 687
E+E N +K+L
Sbjct: 193 EKEKHATENKVKNL 206
Score = 45.6 bits (103), Expect = 2e-04
Identities = 49/240 (20%), Positives = 112/240 (46%), Gaps = 15/240 (6%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+++A + A ++++A + + A A EQ+ D+N R + ++ + L ++E
Sbjct: 903 ERRANLLQAEVEELRATLEQTERARKLA---EQELLDSNERVQLLHTQNTSLIHTKKKLE 959
Query: 229 EDLILNKNKLEQANKD---LEEKEKQLTATEAEVAALNRKVQQIEEDLEKS----EERSG 387
DL+ ++++E A++D EEK K+ A +A +K Q LE+ E+
Sbjct: 960 TDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVK 1019
Query: 388 TAQQKLLEAQQSA-DENNRMCKVLENRAQQ-------DEERMDQLTNQLKEARLLAEDAD 543
Q +L EA+Q A + + LE R ++ ++++ + L++ ++
Sbjct: 1020 DLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELT 1079
Query: 544 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+S+E + + ++D ++ + +VKS + E +E+ + + E+A +R +
Sbjct: 1080 YQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERAD 1139
>M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy chain
protein.
Length = 1937
Score = 60.9 bits (141), Expect = 5e-09
Identities = 45/212 (21%), Positives = 106/212 (50%), Gaps = 5/212 (2%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T ++ + ++ E + + ++ E++A+ A A + EE+++ Q A +E +
Sbjct: 1729 TKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 1785
Query: 244 NKNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
KN LEQ KDL E ++ L + ++ L +V+++E ++E ++R+ A + L
Sbjct: 1786 KKN-LEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLR 1844
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
+ + E + + ++ +D+L ++K + AE+A+ +S+ K ++
Sbjct: 1845 KHDRRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQH 1904
Query: 589 ELEVAEDRVKSGDAKISELEEELKVVGNSLKS 684
ELE AE+R ++++++L + + V + +
Sbjct: 1905 ELEEAEERADIAESQVNKLRVKSREVHTKISA 1936
Score = 57.6 bits (133), Expect = 4e-08
Identities = 57/229 (24%), Positives = 104/229 (45%), Gaps = 7/229 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+++ +A+ +Q+ + + D ++ + ++ + K N EV + + K E
Sbjct: 1323 EEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKY---E 1379
Query: 229 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 387
D I +LE+A K L +E E+ + A A+ A+L + Q+++ EDL ERS
Sbjct: 1380 TDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSN 1439
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
A L + Q++ D KVL Q+ EE +L KE+R L+ + +
Sbjct: 1440 AACAALDKKQRNFD------KVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEE 1493
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
L D+LE K+ +IS+L E++ G + LE +++ Q
Sbjct: 1494 SL----DQLETLRRAHKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQ 1538
Score = 55.2 bits (127), Expect = 2e-07
Identities = 54/241 (22%), Positives = 114/241 (47%), Gaps = 16/241 (6%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQV 225
++K T+ K +Q ++ E D+ D + CEQ ++ ++ E +EV E ++ ++
Sbjct: 877 EEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKN-KIQLEAKIKEVTERAEEEEEI 935
Query: 226 EEDLILNKNKLE----QANKDLEEKE-------KQLTATEAEVAALNRKVQQIEEDLEK- 369
+L K KLE + KD+++ E KQ ATE +V L ++ ++E + K
Sbjct: 936 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKQKHATENKVKNLTEEMAGLDETIAKL 995
Query: 370 SEERSG---TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA 540
S+E+ T QQ L + Q D+ N +L + E+++D L L++ + L D
Sbjct: 996 SKEKKALQETHQQTLDDLQAEEDKVN----ILTKAKTKLEQQVDDLEGSLEQEKKLRMDL 1051
Query: 541 DGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ ++ L ++ E+ + D K+ + E E+ + + ++ + E + +++
Sbjct: 1052 ERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKI 1111
Query: 721 E 723
+
Sbjct: 1112 K 1112
Score = 50.8 bits (116), Expect = 5e-06
Identities = 38/222 (17%), Positives = 102/222 (45%), Gaps = 1/222 (0%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
AT++ ++ + + E +A ++ Q +K+ +V +LQ ++ +V ++
Sbjct: 1693 ATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESR 1752
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA-Q 417
+ K ++A D ++L + A L R + +E+ ++ + R A+Q L+ +
Sbjct: 1753 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGK 1812
Query: 418 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 597
+ + + LE + +++R + L++ ++ +++E + + ++D ++
Sbjct: 1813 KQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHDRRVKELTYQTEEDRKNVLRLQDLVD 1872
Query: 598 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ +VKS + E EE+ + + L+ E+A +R +
Sbjct: 1873 KLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERAD 1914
Score = 44.4 bits (100), Expect = 4e-04
Identities = 47/208 (22%), Positives = 99/208 (47%), Gaps = 22/208 (10%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
+Q+ D + + +++ EL+K QVE++ + LE+A LE +E ++ + E+
Sbjct: 1509 QQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLEL 1568
Query: 322 ----AALNRKVQQIEED---LEKSEERSGTAQQKLLEAQ-QSADENNRMCKVLENRAQQD 477
+ ++RK+ + +E+ L+++ R Q L+A+ +S ++ R+ K +E +
Sbjct: 1569 NQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEM 1628
Query: 478 EERM--------DQLTNQ------LKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 615
E ++ + L N LKE +L +DA +++ +LA VE + + +
Sbjct: 1629 EIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEI 1688
Query: 616 KSGDAKISELEEELKVVGNSLKSLEVSE 699
+ A + + E K+ L L+ SE
Sbjct: 1689 EELWATLEQTERSRKIAEQEL--LDASE 1714
Score = 44.0 bits (99), Expect = 6e-04
Identities = 47/213 (22%), Positives = 97/213 (45%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T+ + K+ +A++ +D E + K+ ++V +L+ L Q E+ L +
Sbjct: 991 TIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQ-EKKLRM 1049
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
+ LE+A + LE K A E+ + N K QQ++E LEK E K +E +Q+
Sbjct: 1050 D---LERAKRKLEGDLK--LAQESTMDMENDK-QQLDEKLEKKEFEISNLISK-IEDEQA 1102
Query: 424 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 603
+ L+ + ++ + R+++L +++ R A+ + ++SR+L + + LE A
Sbjct: 1103 VEIQ------LQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEA 1156
Query: 604 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 702
+ + E E + + L+ + E
Sbjct: 1157 GGATSAQVELNKKREAEFQKLRRDLEEATLQHE 1189
Score = 41.9 bits (94), Expect = 0.002
Identities = 31/141 (21%), Positives = 69/141 (48%), Gaps = 7/141 (4%)
Frame = +1
Query: 307 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
TE E+A + + Q+ +++L KSE + ++K++ + ++ + + EER
Sbjct: 848 TEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEER 907
Query: 487 MDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
+QL ++KE AE+ + + E++ K +EDE + + + ++++
Sbjct: 908 CEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 967
Query: 646 EEELKVVGNSLKSLEVSEEKA 708
E++ N +K+L +EE A
Sbjct: 968 EKQKHATENKVKNL--TEEMA 986
Score = 36.3 bits (80), Expect = 0.11
Identities = 36/188 (19%), Positives = 81/188 (43%), Gaps = 5/188 (2%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKL-AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAE 318
E+Q D + E+++E + E AQVE LNK + + K + E+ EA
Sbjct: 1136 EKQRSDLSRELEEISERLEEAGGATSAQVE----LNKKREAEFQKLRRDLEEATLQHEAM 1191
Query: 319 VAALNRK----VQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
VAAL +K + ++ E ++ + +++ E + D+ + + + E+
Sbjct: 1192 VAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGHLEKM 1251
Query: 487 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 666
L +Q+ + E+ ++++ + A ++ E ++ DA +S+L +
Sbjct: 1252 CRSLEDQVSGLKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEQDALVSQLSRSKQAS 1311
Query: 667 GNSLKSLE 690
++ L+
Sbjct: 1312 TQQIEELK 1319
Score = 36.3 bits (80), Expect = 0.11
Identities = 50/225 (22%), Positives = 100/225 (44%), Gaps = 17/225 (7%)
Frame = +1
Query: 91 QAMKLEKDNAMDKADTCEQQA--RDANLRAEKVNEEVRELQKKLAQVEEDL---ILNKN- 252
Q +LEK + + CE QA +A E ++ +Q +L QV+ ++ I K+
Sbjct: 1525 QIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDE 1584
Query: 253 KLEQANKDLEEKEKQLTAT-EAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
+++Q ++ + + +T +AE+ + N R +++E DL + E + A + E+ +
Sbjct: 1585 EIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLR 1644
Query: 421 SADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLL---AEDADGKSDEVSRKLAF 579
+ + K L++ + E+ +QL + A LL E+ ++ R
Sbjct: 1645 NYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKI 1704
Query: 580 VEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
E EL A +RV+ + + L K + N + L+ E+ Q
Sbjct: 1705 AEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQ 1749
>BC118982-1|AAI18983.1| 553|Homo sapiens KIAA2012 protein protein.
Length = 553
Score = 60.9 bits (141), Expect = 5e-09
Identities = 54/186 (29%), Positives = 92/186 (49%), Gaps = 13/186 (6%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
+++A LRAE+ E++KK + EE L + +LE+A K EE E + E+
Sbjct: 353 QEKASWDRLRAERAEMRWLEVEKKRREQEEQRQLQQEQLERAKKMEEELELEQQRRTEEI 412
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLE--AQQSADENNRMCKVLENRAQQDE----- 480
+++Q+ E+ ++ EER + K + A+Q +E R + L+ + QQ+E
Sbjct: 413 RLRKQRLQE-EQQRQEEEERKQQLRLKAAQERARQQQEEFRRKLRELQRKKQQEEAERAE 471
Query: 481 ---ERMDQLTNQL-KEARLLAEDADGKSDEVSRKLAFVEDE--LEVAEDRVKSGDAKISE 642
+R ++L QL +E + L E A+ + E R+ E++ LE E R K +A
Sbjct: 472 AEKQRQEELEMQLEEEQKHLMEMAEEERLEYQRRKQEAEEKARLEAEERRQKEEEAARLA 531
Query: 643 LEEELK 660
LEE K
Sbjct: 532 LEEATK 537
Score = 40.3 bits (90), Expect = 0.007
Identities = 41/132 (31%), Positives = 62/132 (46%), Gaps = 13/132 (9%)
Frame = +1
Query: 85 KMQAMKLEKDNAMDKADTCEQQAR--DANLRAEKVNEE----VRELQKKLAQVE-EDLIL 243
+++ +L+++ + + +QQ R A RA + EE +RELQ+K Q E E
Sbjct: 413 RLRKQRLQEEQQRQEEEERKQQLRLKAAQERARQQQEEFRRKLRELQRKKQQEEAERAEA 472
Query: 244 NKNKLEQANKDLEEKEKQL-TATEAEVAALNRKVQQIEED--LEKSEER---SGTAQQKL 405
K + E+ LEE++K L E E R+ Q+ EE LE E R A+ L
Sbjct: 473 EKQRQEELEMQLEEEQKHLMEMAEEERLEYQRRKQEAEEKARLEAEERRQKEEEAARLAL 532
Query: 406 LEAQQSADENNR 441
EA + A E R
Sbjct: 533 EEATKQAQEQAR 544
>AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein.
Length = 2069
Score = 60.9 bits (141), Expect = 5e-09
Identities = 53/226 (23%), Positives = 109/226 (48%), Gaps = 1/226 (0%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
Q+ A ++ ++ M ++ + +A ++D E + R++ L AE+ + E Q KL + +
Sbjct: 555 QEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKATECQHKLLKAK 614
Query: 229 EDLILNKNKL-EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
+ K ++ E A + E+QL K+Q+++E LEK+ + S A + L
Sbjct: 615 DQ---GKPEVGEYAKLEKINAEQQL------------KIQELQEKLEKAVKASTEATELL 659
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
+Q+ + R + L+NR E +L + +E R E+ + + + R+ ++
Sbjct: 660 QNIRQAKERAERELEKLQNREDSSEGIRKKLV-EAEERRHSLENKVKRLETMERRENRLK 718
Query: 586 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
D+++ +++ KI ELEE+ + S + LEV ++ Q E
Sbjct: 719 DDIQTKSQQIQQMADKILELEEKHREAQVSAQHLEVHLKQKEQHYE 764
Score = 56.8 bits (131), Expect = 7e-08
Identities = 55/231 (23%), Positives = 102/231 (44%), Gaps = 10/231 (4%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A +++KK+ E ++ DK EQ+ + R +V + + + +L E
Sbjct: 442 AKTSSMEKKLLIKSKELQDSQDKCHKMEQEMTRLHRRVSEVEAVLSQKEVELKASETQRS 501
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
L + L + ++ L EV+ + K Q+ D+ + + +++ E Q
Sbjct: 502 LLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIKEQ--EYQA 559
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE--L 594
+E M LE R D ++L+E+RL AE+ K+ E KL +D+
Sbjct: 560 QVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKATECQHKLLKAKDQGKP 619
Query: 595 EVAE----DRVKS-GDAKISELEEEL-KVVGNSLKSLEVSE--EKANQRVE 723
EV E +++ + KI EL+E+L K V S ++ E+ + +A +R E
Sbjct: 620 EVGEYAKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAE 670
Score = 54.4 bits (125), Expect = 4e-07
Identities = 52/204 (25%), Positives = 95/204 (46%), Gaps = 12/204 (5%)
Frame = +1
Query: 100 KLEKD-NAMDKADTCEQQARDANLRAEKVNEEVRE-------LQKKLAQVEEDLILNKNK 255
KLEK A +A Q R A RAE+ E+++ ++KKL + EE ++
Sbjct: 644 KLEKAVKASTEATELLQNIRQAKERAERELEKLQNREDSSEGIRKKLVEAEE----RRHS 699
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL----EKSEERSGTAQQKLLEAQQS 423
LE K LE E++ + ++ ++++QQ+ + + EK E +AQ + +Q
Sbjct: 700 LENKVKRLETMERRENRLKDDIQTKSQQIQQMADKILELEEKHREAQVSAQHLEVHLKQK 759
Query: 424 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 603
KVL+N+ ++D + L N ++ E+A K +S + A +
Sbjct: 760 EQHYEEKIKVLDNQIKKDLADKETLENMMQRHE---EEAHEKGKILSEQKAMI----NAM 812
Query: 604 EDRVKSGDAKISELEEELKVVGNS 675
+ +++S + +I EL E K+ NS
Sbjct: 813 DSKIRSLEQRIVELSEANKLAANS 836
Score = 52.0 bits (119), Expect = 2e-06
Identities = 59/237 (24%), Positives = 105/237 (44%), Gaps = 19/237 (8%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-------VRELQKKLAQV 225
M A ++ + ++ +K +A E Q R + EK++ + + EL+ +L +V
Sbjct: 844 MKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREV 903
Query: 226 ----EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 393
EE + K +L + L+E+E QLTA +A AAL +++Q + +LE++ +
Sbjct: 904 SLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEE 963
Query: 394 QQKLL----EAQQSADENNRMCKV---LENRAQQDEERMDQLTNQLKEARLLAEDADGKS 552
Q L E Q+ D C V LE + Q E +L NQ ++A G +
Sbjct: 964 IQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGAN 1023
Query: 553 DEVSRKLAFVED-ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
DE+ + + V+ E+ E ++ K + E LK L+ + E N +
Sbjct: 1024 DEIVQLRSEVDHLRREITEREMQLTSQK--QTMEALKTTCTMLEEQVMDLEALNDEL 1078
Score = 44.4 bits (100), Expect = 4e-04
Identities = 56/243 (23%), Positives = 110/243 (45%), Gaps = 18/243 (7%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEK-----VNEEVRELQKK 213
++K +D KK A K +N M + + E + L +K ++ ++R L+++
Sbjct: 764 EEKIKVLDNQIKKDLADKETLENMMQRHEE-EAHEKGKILSEQKAMINAMDSKIRSLEQR 822
Query: 214 LAQVEE--DLILNKNKLEQANKDLEEK-----EKQLTATEAEVAALNRKVQQIEEDLEKS 372
+ ++ E L N + Q N +E+ +Q E + L + +++EE LEK
Sbjct: 823 IVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKI 882
Query: 373 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD----QLTNQLKEARLLAEDA 540
+ + + +LLE + E + LE+ Q+ E + QL+ Q +E++L A A
Sbjct: 883 SHQDHSDKNRLLELETRLREVS-----LEHEEQKLELKRQLTELQLSLQERESQLTALQA 937
Query: 541 DGKSDEVSRKLA--FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
+ E + A +E+ AE+ +++ A E++ + + NS + EE+ NQ
Sbjct: 938 ARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQ 997
Query: 715 RVE 723
E
Sbjct: 998 LTE 1000
Score = 38.3 bits (85), Expect = 0.028
Identities = 52/234 (22%), Positives = 108/234 (46%), Gaps = 11/234 (4%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
Q +A I + Q ++L + +Q ++ L+AE +++++ +L+KK A +E
Sbjct: 1115 QSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLE 1174
Query: 229 EDLILNKNKLEQ----ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE----ERS 384
+ + KLE + LEE+ K + + + R Q ++E L++++ ERS
Sbjct: 1175 MNARSLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERS 1234
Query: 385 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE-- 558
Q LE Q + ++ +E Q + +D L ++ + + + E
Sbjct: 1235 DLEYQ--LENIQVLYSHEKV--KMEGTISQQTKLIDFLQAKMDQPAKKKKGLFSRRKEDP 1290
Query: 559 -VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+ ++ +EL++A ++ K A+ +ELEE L+ L+S EE A+++
Sbjct: 1291 ALPTQVPLQYNELKLALEKEK---ARCAELEEALQKTRIELRS--AREEAAHRK 1339
>AY517555-1|AAT44528.1| 941|Homo sapiens hypothetical
rhabdomyosarcoma antigen MU-RMS-40.3 protein.
Length = 941
Score = 60.9 bits (141), Expect = 5e-09
Identities = 48/218 (22%), Positives = 109/218 (50%), Gaps = 5/218 (2%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T ++ + ++ E ++A A E++A+ A A + EE+++ Q A +E +
Sbjct: 728 TKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 784
Query: 244 NKNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
KN LEQ KDL E ++ L + ++ L +++++E +LE ++++ + + L
Sbjct: 785 KKN-LEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLR 843
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
+ ++ E + + ++ +D+L ++K + AE+AD +++ K +
Sbjct: 844 KYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQH 903
Query: 589 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 702
ELE AE+R ++++++L + + +S + SEE
Sbjct: 904 ELEEAEERADIAESQVNKLRAKTRDFTSSRMVVHESEE 941
Score = 52.0 bits (119), Expect = 2e-06
Identities = 46/223 (20%), Positives = 107/223 (47%), Gaps = 8/223 (3%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
+D + M+++ K N T E Q +A + E++ + EL + ++++ +
Sbjct: 230 IDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEA--- 286
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+ ++ LEEKE ++ A ++ ++++ LE+ + A+ L A QS+
Sbjct: 287 ----GELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENK----AKNALAHALQSS 338
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRKLAFV 582
+ C +L + ++++E +L L +A +A+ DA +++E+ +
Sbjct: 339 RHD---CDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 395
Query: 583 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
L+ +E++V++ +AK + LE+ + + ++ L V E+AN
Sbjct: 396 AQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERAN 438
Score = 51.6 bits (118), Expect = 3e-06
Identities = 48/209 (22%), Positives = 99/209 (47%), Gaps = 15/209 (7%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
EQ+ D + + + + EL+K Q+E + + LE+A LE +E ++ + E+
Sbjct: 508 EQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLEL 567
Query: 322 ----AALNRKVQQIEEDLE---KSEERSGTAQQKLLEAQ-QSADENNRMCKVLENRAQQD 477
+ ++RK+ + +E++E ++ +R+ Q L+A+ +S +E R+ K +E +
Sbjct: 568 TQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEI 627
Query: 478 EERMDQLTNQ----LKEARLL---AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 636
E ++ Q LK R + +D D+ R ++++L + E R A++
Sbjct: 628 EIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEV 687
Query: 637 SELEEELKVVGNSLKSLEVSEEKANQRVE 723
EL L+ + K E +N+RV+
Sbjct: 688 EELRATLEQTERARKLAEQELLDSNERVQ 716
Score = 51.2 bits (117), Expect = 4e-06
Identities = 46/219 (21%), Positives = 101/219 (46%), Gaps = 3/219 (1%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++K+ KLE D+ ++ + + + +++ E + K +++ L +
Sbjct: 219 LEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQ 278
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQ---QIEEDLEKSEERSGTAQQKLLEAQQSA 426
+ + E +QL E+ V+ L+R Q Q E+L++ E A+ L A QS+
Sbjct: 279 KSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSS 338
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
+ C +L + ++++E +L L +A +E A ++ + + E ELE A+
Sbjct: 339 RHD---CDLLREQYEEEQEGKAELQRALSKAN--SEVAQWRTKYETDAIQRTE-ELEEAK 392
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
++ ++ + EE+++ V SLE ++++ VE
Sbjct: 393 KKLAQ---RLQDSEEQVEAVNAKCASLEKTKQRLQGEVE 428
Score = 45.6 bits (103), Expect = 2e-04
Identities = 30/153 (19%), Positives = 74/153 (48%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
QQA D +L+AE+ ++V L K +++E+ + ++ LEQ K + E+ E ++
Sbjct: 6 QQALD-DLQAEE--DKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLK 62
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
+ +E D ++ +ER + + Q ++ + + + ++ + R+++L
Sbjct: 63 LAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEE 122
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 603
+++ R + + + +R+L + + LE A
Sbjct: 123 EIEAERATRAKTEKQRSDYARELEELSERLEEA 155
Score = 45.6 bits (103), Expect = 2e-04
Identities = 49/240 (20%), Positives = 112/240 (46%), Gaps = 15/240 (6%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+++A + A ++++A + + A A EQ+ D+N R + ++ + L ++E
Sbjct: 677 ERRANLLQAEVEELRATLEQTERARKLA---EQELLDSNERVQLLHTQNTSLIHTKKKLE 733
Query: 229 EDLILNKNKLEQANKD---LEEKEKQLTATEAEVAALNRKVQQIEEDLEKS----EERSG 387
DL+ ++++E A++D EEK K+ A +A +K Q LE+ E+
Sbjct: 734 TDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVK 793
Query: 388 TAQQKLLEAQQSA-DENNRMCKVLENRAQQ-------DEERMDQLTNQLKEARLLAEDAD 543
Q +L EA+Q A + + LE R ++ ++++ + L++ ++
Sbjct: 794 DLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELT 853
Query: 544 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+S+E + + ++D ++ + +VKS + E +E+ + + E+A +R +
Sbjct: 854 YQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERAD 913
Score = 39.9 bits (89), Expect = 0.009
Identities = 40/197 (20%), Positives = 94/197 (47%), Gaps = 3/197 (1%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
+++ ++ R E++ EE+ + A+ E+ +LE+ ++ LEE +T+T+ E
Sbjct: 107 QKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEE-AGGVTSTQIE- 164
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEA---QQSADENNRMCKVLENRAQQDEERMD 492
LN+K + L + E + T Q + + A ++ AD + + ++N Q+ +++++
Sbjct: 165 --LNKKREAEFLKLRRDLEEA-TLQHEAMVATLRKKHADSVAELGEQIDN-LQRVKQKLE 220
Query: 493 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 672
+ + E +L +D + VS+ A +E ED++ K E++ L +
Sbjct: 221 K---EKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTT 277
Query: 673 SLKSLEVSEEKANQRVE 723
L+ + ++++E
Sbjct: 278 QKSRLQTEAGELSRQLE 294
Score = 39.5 bits (88), Expect = 0.012
Identities = 28/150 (18%), Positives = 68/150 (45%)
Frame = +1
Query: 259 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 438
+QA DL+ +E ++ + + L ++V+ +E LE+ ++ ++ + +
Sbjct: 6 QQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQ 65
Query: 439 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 618
LEN QQ +ER+ + + + + ED + +K+ ++ +E E+ ++
Sbjct: 66 ESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIE 125
Query: 619 SGDAKISELEEELKVVGNSLKSLEVSEEKA 708
+ A ++ E++ L+ L E+A
Sbjct: 126 AERATRAKTEKQRSDYARELEELSERLEEA 155
>AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain protein.
Length = 1938
Score = 60.9 bits (141), Expect = 5e-09
Identities = 50/216 (23%), Positives = 103/216 (47%), Gaps = 14/216 (6%)
Frame = +1
Query: 106 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL---NKNKLEQANKD 276
+K N DK + ++ D L KV +E + K+ + E++ N +KL + K
Sbjct: 943 KKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKS 1002
Query: 277 LEEKEKQ----LTATEAEVAAL---NRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
L+E +Q L E +V L N K++Q +DLE S E+ + L A++ + +
Sbjct: 1003 LQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGD 1062
Query: 436 NRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 603
+M + LEN QQ EE++ + +L + + +D S + +K+ ++ +E
Sbjct: 1063 LKMSQESIMDLENEKQQIEEKLKKKEFELSQLQARIDDEQVHSLQFQKKIKELQARIEEL 1122
Query: 604 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
E+ +++ +++E++ + L+ + E+A+
Sbjct: 1123 EEEIEAEHTLRAKIEKQRSDLARELEEISERLEEAS 1158
Score = 56.8 bits (131), Expect = 7e-08
Identities = 60/230 (26%), Positives = 111/230 (48%), Gaps = 8/230 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRA-EKVNEEVRELQKKLAQV 225
+++ +A+ +Q+ + + D ++ + EQ+A+ RA K N EV + + K
Sbjct: 1324 EEETKAKNAMAHALQSSRHDCDLLREQYEE-EQEAKAELQRALSKANSEVAQWKTKY--- 1379
Query: 226 EEDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERS 384
E D I +LE+A K L +E E++ ++ A+L + Q+++ EDL + ERS
Sbjct: 1380 ETDAIQRTEELEEAKKKLAQRLQEAEEKTETANSKCASLEKTKQRLQGEVEDLMRDLERS 1439
Query: 385 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 564
TA L + Q++ D KVL Q+ +E +L KE+R L+ + ++
Sbjct: 1440 HTACATLDKKQRNFD------KVLAEWKQKLDESQAELEAAQKESRSLSTEL----FKMR 1489
Query: 565 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
V D+LE K+ +IS+L E++ G +L+ E +++ Q
Sbjct: 1490 NAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQ 1539
Score = 53.6 bits (123), Expect = 7e-07
Identities = 44/171 (25%), Positives = 82/171 (47%), Gaps = 2/171 (1%)
Frame = +1
Query: 199 ELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE 378
E +K++A ++ED K +L ++ +E E+++ + E L +VQ E+L +EE
Sbjct: 848 EAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEE 907
Query: 379 R-SGTAQQK-LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 552
R G + K LLEA+ K L R +++EE +L + +
Sbjct: 908 RCEGLIKSKILLEAK---------VKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDI 958
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
D++ L VE E E++VK+ +++ LEE + + KSL+ + ++
Sbjct: 959 DDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQ 1009
Score = 53.2 bits (122), Expect = 9e-07
Identities = 57/230 (24%), Positives = 108/230 (46%), Gaps = 16/230 (6%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQV 225
++K ++ K +Q ++ E +N MD + CE + L KV E L+++ ++
Sbjct: 878 EEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEE-EEM 936
Query: 226 EEDLILNKNKLEQA----NKDLEEKEKQLT-------ATEAEVAALNRKVQQIEEDLEK- 369
+L+ K LE +D+++ E LT ATE +V L+ ++ +EE++ K
Sbjct: 937 NSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKL 996
Query: 370 -SEERS--GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA 540
E++S QQ L + Q D+ N + K+ QQ D L L++ + L D
Sbjct: 997 TKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQ----TDDLEGSLEQEKKLRADL 1052
Query: 541 DGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
+ RKL E +L+++++ + + + ++EE+LK L L+
Sbjct: 1053 ----ERAKRKL---EGDLKMSQESIMDLENEKQQIEEKLKKKEFELSQLQ 1095
Score = 48.8 bits (111), Expect = 2e-05
Identities = 38/212 (17%), Positives = 92/212 (43%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
M A+++ + + EK + + +Q D + +KVN ++ + KL Q +DL
Sbjct: 986 MTALEENISKLTKEKKSLQEAH---QQTLDDLQVEEDKVNGLIK-INAKLEQQTDDL--- 1038
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+ LEQ K + E+ E ++ + +E + ++ EE+ + +L + Q
Sbjct: 1039 EGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENEKQQIEEKLKKKEFELSQLQARI 1098
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
D+ + + ++ + R+++L +++ L + + +++R+L + + LE A
Sbjct: 1099 DDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEAS 1158
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEE 702
+ + E E + + L+ + E
Sbjct: 1159 GATSAQIEMNKKREAEFQKMRRDLEEATLQHE 1190
Score = 46.4 bits (105), Expect = 1e-04
Identities = 50/229 (21%), Positives = 105/229 (45%), Gaps = 15/229 (6%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 261
++++ MK+ + EQ+ DA+ R + ++ + L ++E D+ + ++E
Sbjct: 1687 EELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVE 1746
Query: 262 ---QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS----EERSGTAQQKLLEAQQ 420
Q +++ EEK K+ A +A +K Q LE+ E+ Q +L EA+Q
Sbjct: 1747 NSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQ 1806
Query: 421 SADENNR-MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS-------RKLA 576
A + + + LENR ++ E +D + EA A + K E++ + +
Sbjct: 1807 LALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDRKNIL 1866
Query: 577 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
++D ++ + +VKS + E EE+ + + ++ E+A +R +
Sbjct: 1867 RLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERAD 1915
Score = 44.8 bits (101), Expect = 3e-04
Identities = 43/200 (21%), Positives = 100/200 (50%), Gaps = 29/200 (14%)
Frame = +1
Query: 73 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 252
++ ++ M+ + +D+ +T ++ ++ + E++ E K L + E+ L +
Sbjct: 1480 SLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQ 1539
Query: 253 K-------LEQANKDLEEKEKQLTATEAEVAA----LNRKVQQIEEDLE---KSEERSGT 390
+ LE+ LE +E ++ + E++ L+RKV + +E++E ++ +R+
Sbjct: 1540 EKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAE 1599
Query: 391 AQQKLLEAQ-QSADENNRMCKVLE-------------NRAQQDEER-MDQLTNQLKEARL 525
A Q +L+A+ +S ++ R+ K +E NR + +R + + QLK+++L
Sbjct: 1600 ALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQRHLRTVQGQLKDSQL 1659
Query: 526 LAEDADGKSDEVSRKLAFVE 585
+DA ++++ +LA VE
Sbjct: 1660 HLDDALRSNEDLKEQLAIVE 1679
>AB095932-1|BAC23108.1| 555|Homo sapiens KIAA2012 protein protein.
Length = 555
Score = 60.9 bits (141), Expect = 5e-09
Identities = 54/186 (29%), Positives = 92/186 (49%), Gaps = 13/186 (6%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
+++A LRAE+ E++KK + EE L + +LE+A K EE E + E+
Sbjct: 355 QEKASWDRLRAERAEMRWLEVEKKRREQEEQRQLQQEQLERAKKMEEELELEQQRRTEEI 414
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLE--AQQSADENNRMCKVLENRAQQDE----- 480
+++Q+ E+ ++ EER + K + A+Q +E R + L+ + QQ+E
Sbjct: 415 RLRKQRLQE-EQQRQEEEERKQQLRLKAAQERARQQQEEFRRKLRELQRKKQQEEAERAE 473
Query: 481 ---ERMDQLTNQL-KEARLLAEDADGKSDEVSRKLAFVEDE--LEVAEDRVKSGDAKISE 642
+R ++L QL +E + L E A+ + E R+ E++ LE E R K +A
Sbjct: 474 AEKQRQEELEMQLEEEQKHLMEMAEEERLEYQRRKQEAEEKARLEAEERRQKEEEAARLA 533
Query: 643 LEEELK 660
LEE K
Sbjct: 534 LEEATK 539
Score = 40.3 bits (90), Expect = 0.007
Identities = 41/132 (31%), Positives = 62/132 (46%), Gaps = 13/132 (9%)
Frame = +1
Query: 85 KMQAMKLEKDNAMDKADTCEQQAR--DANLRAEKVNEE----VRELQKKLAQVE-EDLIL 243
+++ +L+++ + + +QQ R A RA + EE +RELQ+K Q E E
Sbjct: 415 RLRKQRLQEEQQRQEEEERKQQLRLKAAQERARQQQEEFRRKLRELQRKKQQEEAERAEA 474
Query: 244 NKNKLEQANKDLEEKEKQL-TATEAEVAALNRKVQQIEED--LEKSEER---SGTAQQKL 405
K + E+ LEE++K L E E R+ Q+ EE LE E R A+ L
Sbjct: 475 EKQRQEELEMQLEEEQKHLMEMAEEERLEYQRRKQEAEEKARLEAEERRQKEEEAARLAL 534
Query: 406 LEAQQSADENNR 441
EA + A E R
Sbjct: 535 EEATKQAQEQAR 546
>D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heavy
chain protein.
Length = 1939
Score = 60.5 bits (140), Expect = 6e-09
Identities = 60/233 (25%), Positives = 109/233 (46%), Gaps = 18/233 (7%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN----EEVRELQKKLAQVEE- 231
+ +K+K++ K E +D + +Q A EKV+ ++ E + KL + +
Sbjct: 1212 LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRS 1271
Query: 232 --DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR---KVQQIEEDLEKSEERSGTAQ 396
D + KL+ N +L +QL EA ++ L R Q EDL++ E G A+
Sbjct: 1272 LNDFTTQRAKLQTENGELS---RQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAK 1328
Query: 397 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKS 552
L A QSA + C +L + +++ E +L L +A +A+ DA ++
Sbjct: 1329 NALAHALQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQCRTKYETDAIQRT 1385
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
+E+ + L+ AE+ V++ +AK S LE+ + N ++ L V E++N
Sbjct: 1386 EELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1438
Score = 56.8 bits (131), Expect = 7e-08
Identities = 51/229 (22%), Positives = 110/229 (48%), Gaps = 14/229 (6%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 258
K K +LE + M+ T ++ R ++ +++ +L+ LA+VE++ +NK+
Sbjct: 920 KVKEMNERLEDEEEMNAELTAKK--RKLEDECSELKKDIDDLELTLAKVEKEKHATENKV 977
Query: 259 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD--- 429
+ +++ ++ + E AL QQ +DL+ E++ T + ++ +Q D
Sbjct: 978 KNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLSKSKVKLEQQVDDLE 1037
Query: 430 ---ENNRMCKVLENRAQQDEERMDQLTNQ----LKEARL-LAEDADGKSDEVSRKLAFVE 585
E + ++ RA++ E +LT + L+ +L L E K +++++ + +E
Sbjct: 1038 GSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIE 1097
Query: 586 DELEVA---EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
DE +A + ++K A+I ELEEEL+ + +E ++ +E
Sbjct: 1098 DEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELE 1146
Score = 54.0 bits (124), Expect = 5e-07
Identities = 50/233 (21%), Positives = 109/233 (46%), Gaps = 19/233 (8%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 243
++ ++K+++ KLE +A+++A+ + LRA+ + N+ E+++KLA+ +E++
Sbjct: 1528 LEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQ 1587
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGTAQQK--- 402
K ++ L+ T + EV + +K++ ++E L + + AQ++
Sbjct: 1588 AKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKS 1647
Query: 403 ----LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED-------ADGK 549
L + Q D+ R L+ E R + L +L+E R + E AD +
Sbjct: 1648 LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLADRE 1707
Query: 550 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
E S ++ + + ++ K DA +S+L+ E++ ++ E +KA
Sbjct: 1708 LIETSERVQLLHSQNTSLINQKKKMDADLSQLQSEVEEAVQECRNAEEKAKKA 1760
Score = 52.8 bits (121), Expect = 1e-06
Identities = 42/192 (21%), Positives = 86/192 (44%), Gaps = 1/192 (0%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1424 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1483
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
L ++ E LE + + Q+++ + + E + LE +Q E +L
Sbjct: 1484 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQ 1543
Query: 502 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 681
+ L+EA E +GK + +L F + + E+ E ++ D ++ + + + V +SL+
Sbjct: 1544 SALEEAEASLEHEEGKI--LRAQLEFNQIKAEI-ERKLAEKDEEMEQAKRNHQRVVDSLQ 1600
Query: 682 -SLEVSEEKANQ 714
SL+ N+
Sbjct: 1601 TSLDAETRSRNE 1612
Score = 52.4 bits (120), Expect = 2e-06
Identities = 37/141 (26%), Positives = 69/141 (48%), Gaps = 7/141 (4%)
Frame = +1
Query: 307 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
TE E+A + + +I+E LEKSE R ++K++ Q ++ + ++ EER
Sbjct: 847 TEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEER 906
Query: 487 MDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
DQL ++KE ED + + E++ K +EDE + + + ++++
Sbjct: 907 CDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKV 966
Query: 646 EEELKVVGNSLKSLEVSEEKA 708
E+E N +K+L +EE A
Sbjct: 967 EKEKHATENKVKNL--TEEMA 985
Score = 52.4 bits (120), Expect = 2e-06
Identities = 53/218 (24%), Positives = 95/218 (43%), Gaps = 4/218 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLA--- 219
+++ +A+ +Q+ + + D ++ + + + K N EV + + K
Sbjct: 1322 EEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQCRTKYETDA 1381
Query: 220 -QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 396
Q E+L K KL Q +D EE + + A + + ++Q EDL ERS A
Sbjct: 1382 IQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAA 1441
Query: 397 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLA 576
L + Q++ D K+L Q+ EE +L + KEAR L+ + + L
Sbjct: 1442 AALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESL- 1494
Query: 577 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
+ LE + K+ +IS+L E+L G ++ LE
Sbjct: 1495 ---EHLETFKRENKNLQEEISDLTEQLGEGGKNVHELE 1529
Score = 48.8 bits (111), Expect = 2e-05
Identities = 46/215 (21%), Positives = 94/215 (43%), Gaps = 11/215 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEV 195
++K ++ K +Q ++ E+DN D + C+Q + ++ N R E E
Sbjct: 876 EEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 935
Query: 196 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 375
EL K ++E++ K ++ L + EK+ ATE +V L ++ ++E + K
Sbjct: 936 AELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 995
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
+ Q+ +A L + E+++D L L++ + + D +
Sbjct: 996 KEKKALQEAHQQALDDLQAEEDKVNTLSKSKVKLEQQVDDLEGSLEQEKKVRMDL----E 1051
Query: 556 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 660
RKL E +L++ ++ + + +LEE+LK
Sbjct: 1052 RAKRKL---EGDLKLTQESIMDLENDKLQLEEKLK 1083
Score = 48.0 bits (109), Expect = 3e-05
Identities = 32/153 (20%), Positives = 73/153 (47%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
QQA D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 1006 QQALD-DLQAEE--DKVNTLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1062
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
+ +E D + EE+ + + + ++ + L+ + ++++ R+++L
Sbjct: 1063 LTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEE 1122
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 603
+L+ R + ++SR+L + + LE A
Sbjct: 1123 ELEAERTARAKVEKLRSDLSRELEEISERLEEA 1155
Score = 45.2 bits (102), Expect = 2e-04
Identities = 55/224 (24%), Positives = 110/224 (49%), Gaps = 23/224 (10%)
Frame = +1
Query: 79 KKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI-LNK- 249
+++M A + +K D+ ++ D L KV +E + K+ + E++ L++
Sbjct: 931 EEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEI 990
Query: 250 -NKLEQANKDLEEKEKQ----LTATEAEVAALNR---KVQQIEEDLEKSEERSGTAQQKL 405
KL + K L+E +Q L A E +V L++ K++Q +DLE S E+ + L
Sbjct: 991 IAKLTKEKKALQEAHQQALDDLQAEEDKVNTLSKSKVKLEQQVDDLEGSLEQEKKVRMDL 1050
Query: 406 LEAQQSADENNRMCKV----LENRAQQDEERM-------DQLTNQLKEARLLAEDADGKS 552
A++ + + ++ + LEN Q EE++ +Q +++++ ++LA K
Sbjct: 1051 ERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKL 1110
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKI-SELEEELKVVGNSLK 681
E ++ +E+ELE AE ++ K+ S+L EL+ + L+
Sbjct: 1111 KENQARIEELEEELE-AERTARAKVEKLRSDLSRELEEISERLE 1153
Score = 36.7 bits (81), Expect = 0.084
Identities = 45/214 (21%), Positives = 99/214 (46%), Gaps = 15/214 (7%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNA--MDKADTCEQQARDANLRAEKVNEEV-RELQKKLA 219
QQ + D +Q K K+N +++ + + R A + EK+ ++ REL++
Sbjct: 1091 QQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISE 1150
Query: 220 QVEE-------DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLE 366
++EE + +NK + + K + E+ EA AAL +K V ++ E ++
Sbjct: 1151 RLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQID 1210
Query: 367 KSEERSGTAQQKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD 543
+ +++ E + D+ + M ++++ +A E+ L +Q E R+ E+A
Sbjct: 1211 NLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL-EKVSRTLEDQANEYRVKLEEAQ 1269
Query: 544 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
++ + + A ++ E +++ +A IS+L
Sbjct: 1270 RSLNDFTTQRAKLQTENGELSRQLEEKEALISQL 1303
>BC146779-1|AAI46780.1| 1669|Homo sapiens intersectin 2 protein.
Length = 1669
Score = 60.5 bits (140), Expect = 6e-09
Identities = 54/222 (24%), Positives = 106/222 (47%), Gaps = 8/222 (3%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 261
+KMQ + +K + D + N+ EK + + E Q++ + E K + E
Sbjct: 347 QKMQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQR--EAERKAQKEKEEWE 404
Query: 262 QANKDLEEKE-KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 438
+ ++L+E+E K+ E + +Q EE+ K ER A+Q+L ++ E
Sbjct: 405 RKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERI 464
Query: 439 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-------EDELE 597
R ++L N+ +++E + +L ++ K L E +GK ++S +L V + ELE
Sbjct: 465 RRQELL-NQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELE 523
Query: 598 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
V + + +I +L++EL+ N L L ++ N+R++
Sbjct: 524 VLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIK 565
Score = 37.1 bits (82), Expect = 0.064
Identities = 33/153 (21%), Positives = 71/153 (46%), Gaps = 2/153 (1%)
Frame = +1
Query: 52 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 231
+K +K+++ A++ E + + + D+ Q ++ LR E N + L++ L +++
Sbjct: 586 EKEELCQRLKEQLDALEKETASKLSEMDSFNNQLKE--LR-ETYNTQQLALEQ-LYKIKR 641
Query: 232 DLI--LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
D + + + +LE K E E A + + +++ EE+ +K + T Q+K+
Sbjct: 642 DKLKEIERKRLELMQKKKLEDEAARKAKQGKENLWKENLRKEEEEKQKRLQEEKT-QEKI 700
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
E ++ A+E R K ++ E L N
Sbjct: 701 QEEERKAEEKQRKDKDTLKAEEKKRETASVLVN 733
>BC127816-1|AAI27817.1| 416|Homo sapiens Unknown (protein for
IMAGE:40131779) protein.
Length = 416
Score = 60.5 bits (140), Expect = 6e-09
Identities = 38/197 (19%), Positives = 101/197 (51%), Gaps = 2/197 (1%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMD-KADTCEQQARDANLRAEKVNEEVRELQKKL-AQVEEDLILNK 249
+K+K++ KL + +AD ++ + + + + EE EL +L Q EE + +
Sbjct: 205 LKRKLERAKLLLPQQLQAEADHLGKELQSVSAKLQAQVEE-NELWNRLNQQQEEKMWRQE 263
Query: 250 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 429
K+++ + ++E+E+++ E ++ +Q+ EE + + EE+ Q+K+ ++
Sbjct: 264 EKIQEWEEKIQEQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM-QEQEKMRRQEEKIR 322
Query: 430 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 609
E + + + ++ EE++ + +++E + ++ + K E K+ E++++ E+
Sbjct: 323 EQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 382
Query: 610 RVKSGDAKISELEEELK 660
+++ + K+ E E L+
Sbjct: 383 KMRRQEEKMWEQEVRLR 399
Score = 59.3 bits (137), Expect = 1e-08
Identities = 39/204 (19%), Positives = 101/204 (49%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
QQ A D + K++Q++ + +++ + + + + + E+++E ++K+ + E
Sbjct: 218 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 277
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
E + + K+ + + ++E+E+++ E ++ K+++ EE + + EE+ ++K+
Sbjct: 278 EKIREQEEKIREQEEMMQEQEEKMGEQEEKMQE-QEKMRRQEEKIREQEEKIREQKEKIR 336
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
E ++ E + E Q+ EE+M + ++ E + K E K+ E+
Sbjct: 337 EQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCE-------QEEKMQEQEEKMRRQEE 389
Query: 589 ELEVAEDRVKSGDAKISELEEELK 660
++ E R++ + K+ E +E L+
Sbjct: 390 KMWEQEVRLRQQEEKMQEHQEHLE 413
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/154 (17%), Positives = 77/154 (50%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
E++ ++ + ++ E++RE ++K+ + EE + + K+ + + ++E+EK + E ++
Sbjct: 263 EEKIQEWEEKIQEQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEK-MRRQEEKI 321
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
K+++ +E + + EE+ ++K+ E ++ E E + + EE+M +
Sbjct: 322 REQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 381
Query: 502 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 603
+++ + + + + K+ ++ LE A
Sbjct: 382 EKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 415
Score = 49.6 bits (113), Expect = 1e-05
Identities = 28/150 (18%), Positives = 74/150 (49%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 249
+ I+++ + ++ +++ ++ + ++Q + EK+ E Q+K+ + EE + +
Sbjct: 271 EKIQEQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQE-----QEKMRRQEEKIREQE 325
Query: 250 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 429
K+ + + + E+E+++ E ++ +Q+ EE + + EE+ ++K+ E ++
Sbjct: 326 EKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 385
Query: 430 ENNRMCKVLENRAQQDEERMDQLTNQLKEA 519
E R +Q EE+M + L+ A
Sbjct: 386 RQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 415
>AK097517-1|BAC05084.1| 621|Homo sapiens protein ( Homo sapiens cDNA
FLJ40198 fis, clone TESTI2019975, weakly similar to
TRICHOHYALIN. ).
Length = 621
Score = 60.5 bits (140), Expect = 6e-09
Identities = 36/211 (17%), Positives = 105/211 (49%), Gaps = 7/211 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKL--EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 222
Q++ + K++ Q K+ +++ ++ + +Q + + EK++E+ + +++ Q
Sbjct: 394 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQ 453
Query: 223 VEEDLILNKNKLEQANKDLEEKEK-----QLTATEAEVAALNRKVQQIEEDLEKSEERSG 387
+E++ + K+ + + +KEK ++ E +V K+ EE + + EE+
Sbjct: 454 EQEEMWRQEEKIREQEEIWRQKEKMHEQEKIWKQEEKVWRQEEKMHDQEEKIREQEEKMW 513
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
++K+ E ++ E + + + ++ EE++ + +++E + ++ + K E
Sbjct: 514 RQEEKIREQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE 573
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEELK 660
K+ E++++ E++++ + K+ E E L+
Sbjct: 574 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 604
Score = 52.4 bits (120), Expect = 2e-06
Identities = 31/167 (18%), Positives = 84/167 (50%), Gaps = 2/167 (1%)
Frame = +1
Query: 166 LRAEKVNEEVREL--QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK 339
+R E+ +E E+ Q++ + +E++ K K+ + K +++EK + E ++ K
Sbjct: 446 IREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIWKQEEK-VWRQEEKMHDQEEK 504
Query: 340 VQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA 519
+++ EE + + EE+ ++K+ E ++ E + E + + EE++ + ++E
Sbjct: 505 IREQEEKMWRQEEKIREQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQ 564
Query: 520 RLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 660
+ + K E K+ E+++ E+++ + ++ + EE+++
Sbjct: 565 EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 611
Score = 48.8 bits (111), Expect = 2e-05
Identities = 44/229 (19%), Positives = 108/229 (47%), Gaps = 5/229 (2%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL-AQV 225
Q+K +++ K ++Q E +++A Q + A+ + +E++ + KL AQV
Sbjct: 221 QEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ-QQLQAEADHLGKELQSVSAKLQAQV 279
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
EE+ + N+ +Q K ++EK + K+Q+ EE + + EE+ ++K+
Sbjct: 280 EENELWNRLNQQQEEKMWRQEEK--------IQEWEEKIQEQEEKIREQEEKIREQEEKM 331
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL--KEARLL-AEDADGKSDEVSRKLA 576
++ E + E + EE+M +L + KE ++ E+ + +++ +
Sbjct: 332 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEE 391
Query: 577 FVEDELEVAE-DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
++E ++ E ++ + +AK+ EE+++ ++ E + +++
Sbjct: 392 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKI 440
Score = 48.8 bits (111), Expect = 2e-05
Identities = 30/160 (18%), Positives = 77/160 (48%), Gaps = 3/160 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL---QKKLA 219
++K + I ++ + M E++ + + +Q + + EK+ E+ ++ ++K+
Sbjct: 462 EEKIREQEEIWRQKEKMH-EQEKIWKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIR 520
Query: 220 QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 399
+ EE + + K+ + + + E+E+++ E ++ +Q+ EE + + EE+ ++
Sbjct: 521 EQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 580
Query: 400 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA 519
K+ E ++ E R +Q EE+M + L+ A
Sbjct: 581 KMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 620
Score = 47.6 bits (108), Expect = 4e-05
Identities = 26/128 (20%), Positives = 65/128 (50%), Gaps = 1/128 (0%)
Frame = +1
Query: 178 KVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE 357
K E+V ++K+ EE + + K+ + + + E+E+++ E ++ K+++ EE
Sbjct: 486 KQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQKEKIREQEE 545
Query: 358 DLEKSEERSGTAQQKLLEAQQSA-DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 534
+ + EE+ ++ + E ++ ++ +MC+ E + Q+ EE+M + ++ E +
Sbjct: 546 KIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQ-EEKMQEQEEKMRRQEEKMWEQEVRLR 604
Query: 535 DADGKSDE 558
+ K E
Sbjct: 605 QQEEKMQE 612
Score = 43.2 bits (97), Expect = 0.001
Identities = 22/139 (15%), Positives = 67/139 (48%)
Frame = +1
Query: 187 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE 366
E++ + ++K+ + EE + + K+ + + + +E+++ E ++ K+++ +E +
Sbjct: 482 EKIWKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQKEKIR 541
Query: 367 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 546
+ EE+ ++K+ E ++ E E + + EE+M + +++ + +
Sbjct: 542 EQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 601
Query: 547 KSDEVSRKLAFVEDELEVA 603
+ + K+ ++ LE A
Sbjct: 602 RLRQQEEKMQEHQEHLEAA 620
>AK021545-1|BAB13841.1| 436|Homo sapiens protein ( Homo sapiens
cDNA FLJ11483 fis, clone HEMBA1001822, highly similar to
Mus musculus Ese2L protein mRNA. ).
Length = 436
Score = 60.5 bits (140), Expect = 6e-09
Identities = 54/222 (24%), Positives = 106/222 (47%), Gaps = 8/222 (3%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 261
+KMQ + +K + D + N+ EK + + E Q++ + E K + E
Sbjct: 90 QKMQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQR--EAERKAQKEKEEWE 147
Query: 262 QANKDLEEKE-KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 438
+ ++L+E+E K+ E + +Q EE+ K ER A+Q+L ++ E
Sbjct: 148 RKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERI 207
Query: 439 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-------EDELE 597
R ++L N+ +++E + +L ++ K L E +GK ++S +L V + ELE
Sbjct: 208 RRQELL-NQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELE 266
Query: 598 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
V + + +I +L++EL+ N L L ++ N+R++
Sbjct: 267 VLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIK 308
>AF248540-1|AAF63600.1| 1681|Homo sapiens intersectin 2 protein.
Length = 1681
Score = 60.5 bits (140), Expect = 6e-09
Identities = 54/222 (24%), Positives = 106/222 (47%), Gaps = 8/222 (3%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 261
+KMQ + +K + D + N+ EK + + E Q++ + E K + E
Sbjct: 359 QKMQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQR--EAERKAQKEKEEWE 416
Query: 262 QANKDLEEKE-KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 438
+ ++L+E+E K+ E + +Q EE+ K ER A+Q+L ++ E
Sbjct: 417 RKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERI 476
Query: 439 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-------EDELE 597
R ++L N+ +++E + +L ++ K L E +GK ++S +L V + ELE
Sbjct: 477 RRQELL-NQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELE 535
Query: 598 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
V + + +I +L++EL+ N L L ++ N+R++
Sbjct: 536 VLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIK 577
Score = 37.1 bits (82), Expect = 0.064
Identities = 33/153 (21%), Positives = 71/153 (46%), Gaps = 2/153 (1%)
Frame = +1
Query: 52 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 231
+K +K+++ A++ E + + + D+ Q ++ LR E N + L++ L +++
Sbjct: 598 EKEELCQRLKEQLDALEKETASKLSEMDSFNNQLKE--LR-ETYNTQQLALEQ-LYKIKR 653
Query: 232 DLI--LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
D + + + +LE K E E A + + +++ EE+ +K + T Q+K+
Sbjct: 654 DKLKEIERKRLELMQKKKLEDEAARKAKQGKENLWKENLRKEEEEKQKRLQEEKT-QEKI 712
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
E ++ A+E R K ++ E L N
Sbjct: 713 QEEERKAEEKQRKDKDTLKAEEKKRETASVLVN 745
>AF182199-1|AAF59904.1| 1248|Homo sapiens intersectin 2 short isoform
protein.
Length = 1248
Score = 60.5 bits (140), Expect = 6e-09
Identities = 54/222 (24%), Positives = 106/222 (47%), Gaps = 8/222 (3%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 261
+KMQ + +K + D + N+ EK + + E Q++ + E K + E
Sbjct: 347 QKMQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQR--EAERKAQKEKEEWE 404
Query: 262 QANKDLEEKE-KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 438
+ ++L+E+E K+ E + +Q EE+ K ER A+Q+L ++ E
Sbjct: 405 RKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERI 464
Query: 439 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-------EDELE 597
R ++L N+ +++E + +L ++ K L E +GK ++S +L V + ELE
Sbjct: 465 RRQELL-NQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELE 523
Query: 598 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
V + + +I +L++EL+ N L L ++ N+R++
Sbjct: 524 VLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIK 565
Score = 29.9 bits (64), Expect = 9.6
Identities = 30/114 (26%), Positives = 49/114 (42%), Gaps = 8/114 (7%)
Frame = +1
Query: 187 EEVRELQKKLAQVEEDLI-LNKNKLEQAN-KDLEEKEKQLTATEAEVAALNRKVQQIEED 360
+E+RE E L + ++KL++ K LE +K+ EA A K +E+
Sbjct: 647 KELRETYNTQQLALEQLYKIKRDKLKEIERKRLELMQKKKLEDEAARKAKQGKENLWKEN 706
Query: 361 LEKSEE------RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
L K EE + Q+K+ E ++ A+E R K ++ E L N
Sbjct: 707 LRKEEEEKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLKAEEKKRETASVLVN 760
>AF182198-1|AAF59903.1| 1696|Homo sapiens intersectin 2 long isoform
protein.
Length = 1696
Score = 60.5 bits (140), Expect = 6e-09
Identities = 54/222 (24%), Positives = 106/222 (47%), Gaps = 8/222 (3%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 261
+KMQ + +K + D + N+ EK + + E Q++ + E K + E
Sbjct: 347 QKMQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQR--EAERKAQKEKEEWE 404
Query: 262 QANKDLEEKE-KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 438
+ ++L+E+E K+ E + +Q EE+ K ER A+Q+L ++ E
Sbjct: 405 RKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERI 464
Query: 439 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-------EDELE 597
R ++L N+ +++E + +L ++ K L E +GK ++S +L V + ELE
Sbjct: 465 RRQELL-NQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELE 523
Query: 598 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
V + + +I +L++EL+ N L L ++ N+R++
Sbjct: 524 VLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIK 565
Score = 29.9 bits (64), Expect = 9.6
Identities = 30/114 (26%), Positives = 49/114 (42%), Gaps = 8/114 (7%)
Frame = +1
Query: 187 EEVRELQKKLAQVEEDLI-LNKNKLEQAN-KDLEEKEKQLTATEAEVAALNRKVQQIEED 360
+E+RE E L + ++KL++ K LE +K+ EA A K +E+
Sbjct: 647 KELRETYNTQQLALEQLYKIKRDKLKEIERKRLELMQKKKLEDEAARKAKQGKENLWKEN 706
Query: 361 LEKSEE------RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
L K EE + Q+K+ E ++ A+E R K ++ E L N
Sbjct: 707 LRKEEEEKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLKAEEKKRETASVLVN 760
>AF111783-1|AAD29949.1| 1939|Homo sapiens myosin heavy chain IIb
protein.
Length = 1939
Score = 60.5 bits (140), Expect = 6e-09
Identities = 54/219 (24%), Positives = 112/219 (51%), Gaps = 10/219 (4%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
T ++ + ++ E ++ + +A E++A+ A A + EE+++ Q A +E +
Sbjct: 1730 TKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 1786
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLEA 414
KN +EQ KDL QL EAE AL +++Q++E + + E + Q+ +EA
Sbjct: 1787 KKN-MEQTVKDL-----QLRLGEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEA 1840
Query: 415 QQSADENNRMCKVLENRAQQD-------EERMDQLTNQLKEARLLAEDADGKSDEVSRKL 573
+ ++ R K L + ++D ++ +D+L ++K + AE+A+ +S+ K
Sbjct: 1841 VKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKF 1900
Query: 574 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
++ ELE AE+R ++++++L + + V + S E
Sbjct: 1901 RKLQHELEEAEERADIAESQVNKLRVKSREVHTKVISEE 1939
Score = 57.2 bits (132), Expect = 6e-08
Identities = 46/221 (20%), Positives = 104/221 (47%), Gaps = 8/221 (3%)
Frame = +1
Query: 76 IKKKMQA---MKLEKDNAMDKAD-TCEQQARDANLRAE--KVNEEVRELQKKLAQVEEDL 237
IK K+Q +K + A D+ + E A+ L E ++ +++ +L+ LA+VE++
Sbjct: 913 IKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 972
Query: 238 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 417
+NK++ +++ ++ + E AL QQ +DL+ E++ T + + +
Sbjct: 973 HATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLE 1032
Query: 418 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 597
Q D+ + + E +L LK A+ D + +++ KL E E+
Sbjct: 1033 QQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMS 1092
Query: 598 VAEDRVKSGDAKISELEEELKVVGNSLKSL--EVSEEKANQ 714
+ +++ A +L++++K + ++ L E+ E+A++
Sbjct: 1093 NLQGKIEDEQALAMQLQKKIKELQARIEELEEEIEAERASR 1133
Score = 49.2 bits (112), Expect = 1e-05
Identities = 54/188 (28%), Positives = 83/188 (44%), Gaps = 5/188 (2%)
Frame = +1
Query: 142 EQQARDANLRA-EKVNEEVRELQKKLA----QVEEDLILNKNKLEQANKDLEEKEKQLTA 306
EQ+A+ R K N EV + + K Q E+L K KL Q +D EE + + +
Sbjct: 1354 EQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNS 1413
Query: 307 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
A + +++Q EDL ERS A L + Q++ D KVL Q+ EE
Sbjct: 1414 KCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFD------KVLAEWKQKYEET 1467
Query: 487 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 666
+L KE+R L+ + + L D LE + K+ +IS+L E++
Sbjct: 1468 QAELEASQKESRSLSTELFKVKNAYEESL----DHLETLKRENKNLQQEISDLTEQIAEG 1523
Query: 667 GNSLKSLE 690
G + LE
Sbjct: 1524 GKHIHELE 1531
Score = 47.6 bits (108), Expect = 4e-05
Identities = 34/141 (24%), Positives = 69/141 (48%), Gaps = 7/141 (4%)
Frame = +1
Query: 307 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
TE E+A + + ++ +E+L K+E + ++K++ Q ++ + + EER
Sbjct: 849 TEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEER 908
Query: 487 MDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
DQL ++KE AED + + E++ K +EDE + + + ++++
Sbjct: 909 CDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 968
Query: 646 EEELKVVGNSLKSLEVSEEKA 708
E+E N +K+L +EE A
Sbjct: 969 EKEKHATENKVKNL--TEEMA 987
Score = 40.7 bits (91), Expect = 0.005
Identities = 45/214 (21%), Positives = 93/214 (43%), Gaps = 16/214 (7%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
+TMD K Q + K + ++ + + D A ++ ++++ELQ ++ ++EE++
Sbjct: 1069 STMDTENDKQQLNEKLKKKEFEMSNL-QGKIEDEQALAMQLQKKIKELQARIEELEEEIE 1127
Query: 241 LNKNKLEQANK-------DLEEKEKQLT----ATEAEVAALNRK----VQQIEEDLEKSE 375
+ +A K +LEE ++L AT A++ LN+K Q++ DLE+S
Sbjct: 1128 AERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQI-ELNKKREAEFQKMRRDLEEST 1186
Query: 376 -ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 552
+ TA + S E + L+ Q+ E+ +L ++ + E
Sbjct: 1187 LQHEATAAALRKKHADSVAELGKQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAK 1246
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 654
+ +ED+L + + + I+EL +
Sbjct: 1247 ANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQ 1280
>AC009228-1|AAX93122.1| 1329|Homo sapiens unknown protein.
Length = 1329
Score = 60.5 bits (140), Expect = 6e-09
Identities = 54/222 (24%), Positives = 106/222 (47%), Gaps = 8/222 (3%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 261
+KMQ + +K + D + N+ EK + + E Q++ + E K + E
Sbjct: 347 QKMQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQR--EAERKAQKEKEEWE 404
Query: 262 QANKDLEEKE-KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 438
+ ++L+E+E K+ E + +Q EE+ K ER A+Q+L ++ E
Sbjct: 405 RKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERI 464
Query: 439 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-------EDELE 597
R ++L N+ +++E + +L ++ K L E +GK ++S +L V + ELE
Sbjct: 465 RRQELL-NQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELE 523
Query: 598 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
V + + +I +L++EL+ N L L ++ N+R++
Sbjct: 524 VLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIK 565
Score = 29.9 bits (64), Expect = 9.6
Identities = 30/114 (26%), Positives = 49/114 (42%), Gaps = 8/114 (7%)
Frame = +1
Query: 187 EEVRELQKKLAQVEEDLI-LNKNKLEQAN-KDLEEKEKQLTATEAEVAALNRKVQQIEED 360
+E+RE E L + ++KL++ K LE +K+ EA A K +E+
Sbjct: 647 KELRETYNTQQLALEQLYKIKRDKLKEIERKRLELMQKKKLEDEAARKAKQGKENLWKEN 706
Query: 361 LEKSEE------RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
L K EE + Q+K+ E ++ A+E R K ++ E L N
Sbjct: 707 LRKEEEEKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLKAEEKKRETASVLVN 760
>AB033082-1|BAA86570.1| 1676|Homo sapiens KIAA1256 protein protein.
Length = 1676
Score = 60.5 bits (140), Expect = 6e-09
Identities = 54/222 (24%), Positives = 106/222 (47%), Gaps = 8/222 (3%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 261
+KMQ + +K + D + N+ EK + + E Q++ + E K + E
Sbjct: 354 QKMQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQR--EAERKAQKEKEEWE 411
Query: 262 QANKDLEEKE-KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 438
+ ++L+E+E K+ E + +Q EE+ K ER A+Q+L ++ E
Sbjct: 412 RKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERI 471
Query: 439 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-------EDELE 597
R ++L N+ +++E + +L ++ K L E +GK ++S +L V + ELE
Sbjct: 472 RRQELL-NQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELE 530
Query: 598 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
V + + +I +L++EL+ N L L ++ N+R++
Sbjct: 531 VLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIK 572
Score = 37.1 bits (82), Expect = 0.064
Identities = 33/153 (21%), Positives = 71/153 (46%), Gaps = 2/153 (1%)
Frame = +1
Query: 52 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 231
+K +K+++ A++ E + + + D+ Q ++ LR E N + L++ L +++
Sbjct: 593 EKEELCQRLKEQLDALEKETASKLSEMDSFNNQLKE--LR-ETYNTQQLALEQ-LYKIKR 648
Query: 232 DLI--LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
D + + + +LE K E E A + + +++ EE+ +K + T Q+K+
Sbjct: 649 DKLKEIERKRLELMQKKKLEDEAARKAKQGKENLWKENLRKEEEEKQKRLQEEKT-QEKI 707
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
E ++ A+E R K ++ E L N
Sbjct: 708 QEEERKAEEKQRKDKDTLKAEEKKRETASVLVN 740
>Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heavy
chain protein.
Length = 1939
Score = 60.1 bits (139), Expect = 8e-09
Identities = 60/233 (25%), Positives = 109/233 (46%), Gaps = 18/233 (7%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN----EEVRELQKKLAQVEE- 231
+ +K+K++ K E +D + +Q A EKV+ ++ E + KL + +
Sbjct: 1212 LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRS 1271
Query: 232 --DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR---KVQQIEEDLEKSEERSGTAQ 396
D + KL+ N +L +QL EA ++ L R Q EDL++ E G A+
Sbjct: 1272 LNDFTTQRAKLQTENGELA---RQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAK 1328
Query: 397 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKS 552
L A QSA + C +L + +++ E +L L +A +A+ DA ++
Sbjct: 1329 NALAHALQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRT 1385
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
+E+ + L+ AE+ V++ +AK S LE+ + N ++ L V E++N
Sbjct: 1386 EELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1438
Score = 56.0 bits (129), Expect = 1e-07
Identities = 54/226 (23%), Positives = 109/226 (48%), Gaps = 10/226 (4%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 243
++ ++K+++ KLE +A+++A+ + LRA+ + N+ E+++KLA+ +E++
Sbjct: 1528 LEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQ 1587
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
K ++ L+ T + EV + +K +E DL + E + A + EAQ+
Sbjct: 1588 AKRNHQRVVDSLQTSLDAETRSRNEVLRVKKK---MEGDLNEMEIQLSHANRMAAEAQKQ 1644
Query: 424 ADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVSRKLA 576
+ K L++ + +++ + + N L +A L A + E SRKLA
Sbjct: 1645 VKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 1704
Query: 577 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
E EL +RV+ ++ + L + K + + L L+ E+A Q
Sbjct: 1705 --EQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQ 1748
Score = 55.2 bits (127), Expect = 2e-07
Identities = 50/229 (21%), Positives = 110/229 (48%), Gaps = 14/229 (6%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 258
K K +LE + M+ T ++ R ++ +++ +L+ LA+VE++ +NK+
Sbjct: 920 KVKEMNERLEDEEEMNAELTAKK--RKLEDECSELKKDIDDLELTLAKVEKEKHATENKV 977
Query: 259 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD--- 429
+ +++ ++ + E AL QQ +DL+ E++ + + ++ +Q D
Sbjct: 978 KNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLE 1037
Query: 430 ---ENNRMCKVLENRAQQDEERMDQLTNQ----LKEARL-LAEDADGKSDEVSRKLAFVE 585
E + ++ RA++ E +LT + L+ +L L E K +++++ + +E
Sbjct: 1038 GSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIE 1097
Query: 586 DELEVA---EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
DE +A + ++K A+I ELEEEL+ + +E ++ +E
Sbjct: 1098 DEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELE 1146
Score = 52.8 bits (121), Expect = 1e-06
Identities = 42/192 (21%), Positives = 86/192 (44%), Gaps = 1/192 (0%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1424 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1483
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
L ++ E LE + + Q+++ + + E + LE +Q E +L
Sbjct: 1484 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQ 1543
Query: 502 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 681
+ L+EA E +GK + +L F + + E+ E ++ D ++ + + + V +SL+
Sbjct: 1544 SALEEAEASLEHEEGKI--LRAQLEFNQIKAEI-ERKLAEKDEEMEQAKRNHQRVVDSLQ 1600
Query: 682 -SLEVSEEKANQ 714
SL+ N+
Sbjct: 1601 TSLDAETRSRNE 1612
Score = 52.4 bits (120), Expect = 2e-06
Identities = 37/141 (26%), Positives = 69/141 (48%), Gaps = 7/141 (4%)
Frame = +1
Query: 307 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
TE E+A + + +I+E LEKSE R ++K++ Q ++ + ++ EER
Sbjct: 847 TEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEER 906
Query: 487 MDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
DQL ++KE ED + + E++ K +EDE + + + ++++
Sbjct: 907 CDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKV 966
Query: 646 EEELKVVGNSLKSLEVSEEKA 708
E+E N +K+L +EE A
Sbjct: 967 EKEKHATENKVKNL--TEEMA 985
Score = 52.0 bits (119), Expect = 2e-06
Identities = 53/218 (24%), Positives = 95/218 (43%), Gaps = 4/218 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLA--- 219
+++ +A+ +Q+ + + D ++ + + + K N EV + + K
Sbjct: 1322 EEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1381
Query: 220 -QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 396
Q E+L K KL Q +D EE + + A + + ++Q EDL ERS A
Sbjct: 1382 IQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAA 1441
Query: 397 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLA 576
L + Q++ D K+L Q+ EE +L + KEAR L+ + + L
Sbjct: 1442 AALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESL- 1494
Query: 577 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
+ LE + K+ +IS+L E+L G ++ LE
Sbjct: 1495 ---EHLETFKRENKNLQEEISDLTEQLGEGGKNVHELE 1529
Score = 48.8 bits (111), Expect = 2e-05
Identities = 38/188 (20%), Positives = 85/188 (45%), Gaps = 3/188 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMK-LEKDNA-MDKADTCEQQARDANLRAEKVNEE-VRELQKKLA 219
++K AT + +K + M L++ A + K Q+A L +V E+ V L K
Sbjct: 968 KEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKV 1027
Query: 220 QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 399
++E+ + + LEQ K + E+ E ++ + +E D + EE+ +
Sbjct: 1028 KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEF 1087
Query: 400 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 579
+ + ++ + L+ + ++++ R+++L +L+ R + ++SR+L
Sbjct: 1088 DINQQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEE 1147
Query: 580 VEDELEVA 603
+ + LE A
Sbjct: 1148 ISERLEEA 1155
Score = 47.6 bits (108), Expect = 4e-05
Identities = 46/215 (21%), Positives = 94/215 (43%), Gaps = 11/215 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEV 195
++K ++ K +Q ++ E+DN D + C+Q + ++ N R E E
Sbjct: 876 EEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 935
Query: 196 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 375
EL K ++E++ K ++ L + EK+ ATE +V L ++ ++E + K
Sbjct: 936 AELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 995
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
+ Q+ +A L + E+++D L L++ + + D +
Sbjct: 996 KEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDL----E 1051
Query: 556 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 660
RKL E +L++ ++ + + +LEE+LK
Sbjct: 1052 RAKRKL---EGDLKLTQESIMDLENDKLQLEEKLK 1083
Score = 43.2 bits (97), Expect = 0.001
Identities = 54/224 (24%), Positives = 109/224 (48%), Gaps = 23/224 (10%)
Frame = +1
Query: 79 KKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI-LNK- 249
+++M A + +K D+ ++ D L KV +E + K+ + E++ L++
Sbjct: 931 EEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEI 990
Query: 250 -NKLEQANKDLEEKEKQ----LTATEAEVAALNR---KVQQIEEDLEKSEERSGTAQQKL 405
KL + K L+E +Q L E +V +L++ K++Q +DLE S E+ + L
Sbjct: 991 IAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDL 1050
Query: 406 LEAQQSADENNRMCKV----LENRAQQDEERM-------DQLTNQLKEARLLAEDADGKS 552
A++ + + ++ + LEN Q EE++ +Q +++++ + LA K
Sbjct: 1051 ERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQALALQLQKKL 1110
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKI-SELEEELKVVGNSLK 681
E ++ +E+ELE AE ++ K+ S+L EL+ + L+
Sbjct: 1111 KENQARIEELEEELE-AERTARAKVEKLRSDLSRELEEISERLE 1153
Score = 36.7 bits (81), Expect = 0.084
Identities = 45/214 (21%), Positives = 99/214 (46%), Gaps = 15/214 (7%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNA--MDKADTCEQQARDANLRAEKVNEEV-RELQKKLA 219
QQ + D +Q K K+N +++ + + R A + EK+ ++ REL++
Sbjct: 1091 QQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISE 1150
Query: 220 QVEE-------DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLE 366
++EE + +NK + + K + E+ EA AAL +K V ++ E ++
Sbjct: 1151 RLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQID 1210
Query: 367 KSEERSGTAQQKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD 543
+ +++ E + D+ + M ++++ +A E+ L +Q E R+ E+A
Sbjct: 1211 NLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL-EKVSRTLEDQANEYRVKLEEAQ 1269
Query: 544 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
++ + + A ++ E +++ +A IS+L
Sbjct: 1270 RSLNDFTTQRAKLQTENGELARQLEEKEALISQL 1303
>BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6,
cardiac muscle, alpha (cardiomyopathy, hypertrophic 1)
protein.
Length = 1939
Score = 60.1 bits (139), Expect = 8e-09
Identities = 60/233 (25%), Positives = 109/233 (46%), Gaps = 18/233 (7%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN----EEVRELQKKLAQVEE- 231
+ +K+K++ K E +D + +Q A EKV+ ++ E + KL + +
Sbjct: 1212 LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRS 1271
Query: 232 --DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR---KVQQIEEDLEKSEERSGTAQ 396
D + KL+ N +L +QL EA ++ L R Q EDL++ E G A+
Sbjct: 1272 LNDFTTQRAKLQTENGELA---RQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAK 1328
Query: 397 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKS 552
L A QSA + C +L + +++ E +L L +A +A+ DA ++
Sbjct: 1329 NALAHALQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRT 1385
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
+E+ + L+ AE+ V++ +AK S LE+ + N ++ L V E++N
Sbjct: 1386 EELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1438
Score = 56.0 bits (129), Expect = 1e-07
Identities = 54/226 (23%), Positives = 109/226 (48%), Gaps = 10/226 (4%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 243
++ ++K+++ KLE +A+++A+ + LRA+ + N+ E+++KLA+ +E++
Sbjct: 1528 LEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQ 1587
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
K ++ L+ T + EV + +K +E DL + E + A + EAQ+
Sbjct: 1588 AKRNHQRVVDSLQTSLDAETRSRNEVLRVKKK---MEGDLNEMEIQLSHANRMAAEAQKQ 1644
Query: 424 ADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVSRKLA 576
+ K L++ + +++ + + N L +A L A + E SRKLA
Sbjct: 1645 VKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 1704
Query: 577 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
E EL +RV+ ++ + L + K + + L L+ E+A Q
Sbjct: 1705 --EQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQ 1748
Score = 54.8 bits (126), Expect = 3e-07
Identities = 50/229 (21%), Positives = 110/229 (48%), Gaps = 14/229 (6%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 258
K K +LE + M+ T ++ R ++ +++ +L+ LA+VE++ +NK+
Sbjct: 920 KVKEMNERLEDEEEMNAELTAKK--RKLEDECSELKKDIDDLELTLAKVEKEKHATENKV 977
Query: 259 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD--- 429
+ +++ ++ + E AL QQ +DL+ E++ + + ++ +Q D
Sbjct: 978 KNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLE 1037
Query: 430 ---ENNRMCKVLENRAQQDEERMDQLTNQ----LKEARL-LAEDADGKSDEVSRKLAFVE 585
E + ++ RA++ E +LT + L+ +L L E K +++++ + +E
Sbjct: 1038 GSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIE 1097
Query: 586 DELEVA---EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
DE +A + ++K A+I ELEEEL+ + +E ++ +E
Sbjct: 1098 DEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELE 1146
Score = 52.8 bits (121), Expect = 1e-06
Identities = 42/192 (21%), Positives = 86/192 (44%), Gaps = 1/192 (0%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1424 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1483
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
L ++ E LE + + Q+++ + + E + LE +Q E +L
Sbjct: 1484 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQ 1543
Query: 502 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 681
+ L+EA E +GK + +L F + + E+ E ++ D ++ + + + V +SL+
Sbjct: 1544 SALEEAEASLEHEEGKI--LRAQLEFNQIKAEI-ERKLAEKDEEMEQAKRNHQRVVDSLQ 1600
Query: 682 -SLEVSEEKANQ 714
SL+ N+
Sbjct: 1601 TSLDAETRSRNE 1612
Score = 52.4 bits (120), Expect = 2e-06
Identities = 37/141 (26%), Positives = 69/141 (48%), Gaps = 7/141 (4%)
Frame = +1
Query: 307 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
TE E+A + + +I+E LEKSE R ++K++ Q ++ + ++ EER
Sbjct: 847 TEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEER 906
Query: 487 MDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
DQL ++KE ED + + E++ K +EDE + + + ++++
Sbjct: 907 CDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKV 966
Query: 646 EEELKVVGNSLKSLEVSEEKA 708
E+E N +K+L +EE A
Sbjct: 967 EKEKHATENKVKNL--TEEMA 985
Score = 52.0 bits (119), Expect = 2e-06
Identities = 53/218 (24%), Positives = 95/218 (43%), Gaps = 4/218 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLA--- 219
+++ +A+ +Q+ + + D ++ + + + K N EV + + K
Sbjct: 1322 EEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1381
Query: 220 -QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 396
Q E+L K KL Q +D EE + + A + + ++Q EDL ERS A
Sbjct: 1382 IQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAA 1441
Query: 397 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLA 576
L + Q++ D K+L Q+ EE +L + KEAR L+ + + L
Sbjct: 1442 AALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESL- 1494
Query: 577 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
+ LE + K+ +IS+L E+L G ++ LE
Sbjct: 1495 ---EHLETFKRENKNLQEEISDLTEQLGEGGKNVHELE 1529
Score = 48.0 bits (109), Expect = 3e-05
Identities = 38/188 (20%), Positives = 85/188 (45%), Gaps = 3/188 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMK-LEKDNA-MDKADTCEQQARDANLRAEKVNEE-VRELQKKLA 219
++K AT + +K + M L++ A + K Q+A L +V E+ V L K
Sbjct: 968 KEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKV 1027
Query: 220 QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 399
++E+ + + LEQ K + E+ E ++ + +E D + EE+ +
Sbjct: 1028 KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEF 1087
Query: 400 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 579
+ + ++ + L+ + ++++ R+++L +L+ R + ++SR+L
Sbjct: 1088 DINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEE 1147
Query: 580 VEDELEVA 603
+ + LE A
Sbjct: 1148 ISERLEEA 1155
Score = 47.6 bits (108), Expect = 4e-05
Identities = 46/215 (21%), Positives = 94/215 (43%), Gaps = 11/215 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEV 195
++K ++ K +Q ++ E+DN D + C+Q + ++ N R E E
Sbjct: 876 EEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 935
Query: 196 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 375
EL K ++E++ K ++ L + EK+ ATE +V L ++ ++E + K
Sbjct: 936 AELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 995
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
+ Q+ +A L + E+++D L L++ + + D +
Sbjct: 996 KEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDL----E 1051
Query: 556 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 660
RKL E +L++ ++ + + +LEE+LK
Sbjct: 1052 RAKRKL---EGDLKLTQESIMDLENDKLQLEEKLK 1083
Score = 44.0 bits (99), Expect = 6e-04
Identities = 54/224 (24%), Positives = 110/224 (49%), Gaps = 23/224 (10%)
Frame = +1
Query: 79 KKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI-LNK- 249
+++M A + +K D+ ++ D L KV +E + K+ + E++ L++
Sbjct: 931 EEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEI 990
Query: 250 -NKLEQANKDLEEKEKQ----LTATEAEVAALNR---KVQQIEEDLEKSEERSGTAQQKL 405
KL + K L+E +Q L E +V +L++ K++Q +DLE S E+ + L
Sbjct: 991 IAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDL 1050
Query: 406 LEAQQSADENNRMCKV----LENRAQQDEERM-------DQLTNQLKEARLLAEDADGKS 552
A++ + + ++ + LEN Q EE++ +Q +++++ ++LA K
Sbjct: 1051 ERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKL 1110
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKI-SELEEELKVVGNSLK 681
E ++ +E+ELE AE ++ K+ S+L EL+ + L+
Sbjct: 1111 KENQARIEELEEELE-AERTARAKVEKLRSDLSRELEEISERLE 1153
Score = 36.3 bits (80), Expect = 0.11
Identities = 45/214 (21%), Positives = 99/214 (46%), Gaps = 15/214 (7%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNA--MDKADTCEQQARDANLRAEKVNEEV-RELQKKLA 219
QQ + D +Q K K+N +++ + + R A + EK+ ++ REL++
Sbjct: 1091 QQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISE 1150
Query: 220 QVEE-------DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLE 366
++EE + +NK + + K + E+ EA AAL +K V ++ E ++
Sbjct: 1151 RLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQID 1210
Query: 367 KSEERSGTAQQKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD 543
+ +++ E + D+ + M ++++ +A E+ L +Q E R+ E+A
Sbjct: 1211 NLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL-EKVSRTLEDQANEYRVKLEEAQ 1269
Query: 544 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
++ + + A ++ E +++ +A IS+L
Sbjct: 1270 RSLNDFTTQRAKLQTENGELARQLEEKEALISQL 1303
>Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9,
non-muscle protein.
Length = 1960
Score = 59.7 bits (138), Expect = 1e-08
Identities = 43/193 (22%), Positives = 93/193 (48%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
Q RD R E+ E+ ++L +++ ++E +L + + A ++ E L EA +
Sbjct: 1568 QFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHID 1627
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
+ N+ + + L K + + ++L + + S +E K E + + E M QL
Sbjct: 1628 SANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQE 1687
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 684
+L A A + DE++ ++A + +A + + +A+I++LEEEL+ + +
Sbjct: 1688 ELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTEL 1747
Query: 685 LEVSEEKANQRVE 723
+ +KAN +++
Sbjct: 1748 INDRLKKANLQID 1760
Score = 55.6 bits (128), Expect = 2e-07
Identities = 47/189 (24%), Positives = 83/189 (43%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
E Q +D ++ N + L KL QVE++ + +LE+ + EKQ+ A+V
Sbjct: 1307 ESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQV 1366
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
A + +K++ LE +EE Q+ L Q +E LE + ++ +D L
Sbjct: 1367 ADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLL 1426
Query: 502 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 681
L R A + + K + + LA E++ A+ + A+ E+E K + +
Sbjct: 1427 VDLDHQRQSACNLEKKQKKFDQLLA--EEKTISAKYAEERDRAEAEAREKETKALSLARA 1484
Query: 682 SLEVSEEKA 708
E E+KA
Sbjct: 1485 LEEAMEQKA 1493
Score = 53.6 bits (123), Expect = 7e-07
Identities = 56/236 (23%), Positives = 111/236 (47%), Gaps = 23/236 (9%)
Frame = +1
Query: 73 AIKKKMQAMK-LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 249
A K + +A+K L K A K C ++ D E++ + +E +KKL +E ++I +
Sbjct: 1629 ANKNRDEAIKQLRKLQAQMK--DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQ 1686
Query: 250 NKL---EQANKDLEEKEKQLTATEA-----------EVAALNRKVQQIEEDLEKSEERSG 387
+L E+A + +++ +L A E L ++ Q+EE+LE+ + +
Sbjct: 1687 EELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTE 1746
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG--KS--- 552
+L +A D+ N + + AQ++E QL Q KE ++ ++ +G KS
Sbjct: 1747 LINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYK 1806
Query: 553 ---DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
+ K+A +E++L+ ++ ++ E++LK V L+V +E+ N
Sbjct: 1807 ASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDV-----LLQVDDERRN 1857
Score = 51.2 bits (117), Expect = 4e-06
Identities = 52/229 (22%), Positives = 107/229 (46%), Gaps = 4/229 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE----KVNEEVRELQKKL 216
++K+ ++ +K K +AM + + + + + Q+ + E +++++ ELQ ++
Sbjct: 1012 EEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQI 1071
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 396
A+++ L + +L+ A +EE+ Q ++ L ++ +++EDLE SE S
Sbjct: 1072 AELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLE-SERASRNKA 1130
Query: 397 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLA 576
+K Q D + + LE + E+ +D Q +E R E EV+
Sbjct: 1131 EK-----QKRD----LGEELEALKTELEDTLDSTAAQ-QELRSKREQ------EVNILKK 1174
Query: 577 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+E+E + E +++ K S+ EEL K ++ + EKA Q +E
Sbjct: 1175 TLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLE 1223
Score = 49.6 bits (113), Expect = 1e-05
Identities = 45/189 (23%), Positives = 90/189 (47%), Gaps = 5/189 (2%)
Frame = +1
Query: 172 AEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTAT--EAEVAALNRKVQ 345
AE+V ++++ + L+Q E+ + +KLE+ L+++ L +A N + +
Sbjct: 1383 AEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKK 1442
Query: 346 QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQ---LTNQLKE 516
Q + D +EE++ +A+ + A+ + K L + A+ EE M+Q L K+
Sbjct: 1443 QKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKAL-SLARALEEAMEQKAELERLNKQ 1501
Query: 517 ARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVS 696
R ED D+V + + +E E +V+ ++ ELE+EL+ ++ LEV+
Sbjct: 1502 FRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVN 1561
Query: 697 EEKANQRVE 723
+ + E
Sbjct: 1562 LQAMKAQFE 1570
Score = 47.6 bits (108), Expect = 4e-05
Identities = 46/229 (20%), Positives = 104/229 (45%), Gaps = 11/229 (4%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
++ + + + KLE++ + + C+ A++ L +++ E L ++ + + L
Sbjct: 964 LEKVTTEAKLKKLEEEQIILEDQNCKL-AKEKKLLEDRIAEFTTNLTEE-EEKSKSLAKL 1021
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK--SEERSGTAQQKLLEAQQ 420
KNK E DLEE+ ++ E+ RK++ DL +E ++ A+ K+ A++
Sbjct: 1022 KNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKK 1081
Query: 421 SADENNRMCKVLENRAQQD---------EERMDQLTNQLKEARLLAEDADGKSDEVSRKL 573
+ + +V E AQ++ E ++ +L L+ R A+ + ++ +L
Sbjct: 1082 EEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEEL 1141
Query: 574 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
++ ELE D + S+ E+E+ ++ +L+ + E Q +
Sbjct: 1142 EALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEM 1190
Score = 45.6 bits (103), Expect = 2e-04
Identities = 48/227 (21%), Positives = 101/227 (44%), Gaps = 24/227 (10%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 222
++ A +A +K+ +A+ L + + AM++ E+ + E + ++ K + +
Sbjct: 1463 ERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHE 1522
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 390
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E+S
Sbjct: 1523 LEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEE 1582
Query: 391 AQQKL------LEAQQSADENNRMCKV------------LENRAQQDEERMDQLTNQLKE 516
+++L +EA+ + R V LE + D+ QL++
Sbjct: 1583 KKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK 1642
Query: 517 ARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 657
+ +D + D+ + + + E ++KS +A++ +L+EEL
Sbjct: 1643 LQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEEL 1689
Score = 45.6 bits (103), Expect = 2e-04
Identities = 52/239 (21%), Positives = 109/239 (45%), Gaps = 18/239 (7%)
Frame = +1
Query: 61 ATMDA---IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNE---EVRELQKKLA- 219
AT DA ++ +QAMK + + + D ++ + +R + E E Q+ +A
Sbjct: 1550 ATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAV 1609
Query: 220 ----QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK--SEER 381
++E DL + ++ ANK+ +E KQL +A++ R++ E+ ++ +
Sbjct: 1610 AARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAK 1669
Query: 382 SGTAQQKLLEAQQ-SADENNRMCKVLENRAQQD-EERMDQLTNQLKEARLLAED---ADG 546
+ K +EA+ E + + +AQQ+ +E D++ N + L E+ +
Sbjct: 1670 ENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEA 1729
Query: 547 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ ++ +L + E+ DR+K + +I ++ +L N +S E A Q++E
Sbjct: 1730 RIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDL----NLERSHAQKNENARQQLE 1784
Score = 43.2 bits (97), Expect = 0.001
Identities = 55/245 (22%), Positives = 112/245 (45%), Gaps = 26/245 (10%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMD--KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED 234
A + ++ ++ A K E + +A E++ R +L+AEK +++Q+ + ++EE
Sbjct: 897 AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEK-----KKMQQNIQELEEQ 951
Query: 235 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 414
L ++ ++ + E +L E E L + ++ ++ + E+R L E
Sbjct: 952 LEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEE 1011
Query: 415 QQSA-------DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR-- 567
++ + +++ M LE R +++E++ +L K R L D+ SD+++
Sbjct: 1012 EEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELE---KTRRKLEGDSTDLSDQIAELQ 1068
Query: 568 --------KLAFVEDELEVAEDRVKSGDA-------KISELEEELKVVGNSLKSLEVSEE 702
+LA E+EL+ A RV+ A KI ELE ++ + L+S S
Sbjct: 1069 AQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRN 1128
Query: 703 KANQR 717
KA ++
Sbjct: 1129 KAEKQ 1133
Score = 40.3 bits (90), Expect = 0.007
Identities = 41/225 (18%), Positives = 98/225 (43%), Gaps = 8/225 (3%)
Frame = +1
Query: 73 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 252
++ K++ ++ EK++ ++ + E+ + + ++ +V +++KK+ L +
Sbjct: 1326 SLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEE 1385
Query: 253 KLEQANKDLE----EKEKQLTATEAEVAALNRKVQQIEE---DLEKSEERSGTAQQKLLE 411
+ KDLE E+++ A + R Q++++ DL+ + + ++K +
Sbjct: 1386 VKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKK 1445
Query: 412 AQQ-SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
Q A+E K E R + + E ++ T L AR L E + K+ E+ R
Sbjct: 1446 FDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKA-ELERLNKQFRT 1504
Query: 589 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
E+E + ELE+ + + ++ ++ E+ ++
Sbjct: 1505 EMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQ 1549
Score = 33.1 bits (72), Expect = 1.0
Identities = 35/183 (19%), Positives = 82/183 (44%), Gaps = 18/183 (9%)
Frame = +1
Query: 166 LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 345
L+ + EE+ +++L +V E + +N+L + +E + QL A + ++ +
Sbjct: 838 LQVSRQEEEMMAKEEELVKVREKQLAAENRLTE----METLQSQLMAEKLQLQEQLQAET 893
Query: 346 QIEEDLEKSEERSGTAQQKLLEA----QQSADENNRMC-------KVLENRAQQDEERMD 492
++ + E+ R +Q+L E + +E C K ++ Q+ EE+++
Sbjct: 894 ELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLE 953
Query: 493 QLTNQLKEARLLAEDADGKSDEVSRKLAFVED-------ELEVAEDRVKSGDAKISELEE 651
+ + ++ +L + K ++ + +ED E ++ EDR+ ++E EE
Sbjct: 954 EEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEE 1013
Query: 652 ELK 660
+ K
Sbjct: 1014 KSK 1016
>M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle
myosin heavy chain (NMHC) mRNA, 3' end. ).
Length = 1247
Score = 59.7 bits (138), Expect = 1e-08
Identities = 43/193 (22%), Positives = 93/193 (48%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
Q RD R E+ E+ ++L +++ ++E +L + + A ++ E L EA +
Sbjct: 855 QFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHID 914
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
+ N+ + + L K + + ++L + + S +E K E + + E M QL
Sbjct: 915 SANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQE 974
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 684
+L A A + DE++ ++A + +A + + +A+I++LEEEL+ + +
Sbjct: 975 ELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTEL 1034
Query: 685 LEVSEEKANQRVE 723
+ +KAN +++
Sbjct: 1035 INDRLKKANLQID 1047
Score = 51.2 bits (117), Expect = 4e-06
Identities = 52/229 (22%), Positives = 107/229 (46%), Gaps = 4/229 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE----KVNEEVRELQKKL 216
++K+ ++ +K K +AM + + + + + Q+ + E +++++ ELQ ++
Sbjct: 298 EEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQI 357
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 396
A+++ L + +L+ A +EE+ Q ++ L ++ +++EDLE SE S
Sbjct: 358 AELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLE-SERASRNKA 416
Query: 397 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLA 576
+K Q D + + LE + E+ +D Q +E R E EV+
Sbjct: 417 EK-----QKRD----LGEELEALKTELEDTLDSTAAQ-QELRSKREQ------EVNILKK 460
Query: 577 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+E+E + E +++ K S+ EEL K ++ + EKA Q +E
Sbjct: 461 TLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLE 509
Score = 49.6 bits (113), Expect = 1e-05
Identities = 45/189 (23%), Positives = 90/189 (47%), Gaps = 5/189 (2%)
Frame = +1
Query: 172 AEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTAT--EAEVAALNRKVQ 345
AE+V ++++ + L+Q E+ + +KLE+ L+++ L +A N + +
Sbjct: 670 AEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKK 729
Query: 346 QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQ---LTNQLKE 516
Q + D +EE++ +A+ + A+ + K L + A+ EE M+Q L K+
Sbjct: 730 QKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKAL-SLARALEEAMEQKAELERLNKQ 788
Query: 517 ARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVS 696
R ED D+V + + +E E +V+ ++ ELE+EL+ ++ LEV+
Sbjct: 789 FRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVN 848
Query: 697 EEKANQRVE 723
+ + E
Sbjct: 849 LQAMKAQFE 857
Score = 47.6 bits (108), Expect = 4e-05
Identities = 46/229 (20%), Positives = 104/229 (45%), Gaps = 11/229 (4%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
++ + + + KLE++ + + C+ A++ L +++ E L ++ + + L
Sbjct: 250 LEKVTTEAKLKKLEEEQIILEDQNCKL-AKEKKLLEDRIAEFTTNLTEE-EEKSKSLAKL 307
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK--SEERSGTAQQKLLEAQQ 420
KNK E DLEE+ ++ E+ RK++ DL +E ++ A+ K+ A++
Sbjct: 308 KNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKK 367
Query: 421 SADENNRMCKVLENRAQQD---------EERMDQLTNQLKEARLLAEDADGKSDEVSRKL 573
+ + +V E AQ++ E ++ +L L+ R A+ + ++ +L
Sbjct: 368 EEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEEL 427
Query: 574 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
++ ELE D + S+ E+E+ ++ +L+ + E Q +
Sbjct: 428 EALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEM 476
Score = 47.6 bits (108), Expect = 4e-05
Identities = 49/224 (21%), Positives = 102/224 (45%), Gaps = 11/224 (4%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++K Q ++ E+ ++ Q RD+ + +KV +++ELQ K + E +K
Sbjct: 501 LEKAKQTLENERGELANEVKVLLQGGRDSEHKRKKVEAQLQELQVKFNEGERVRTELADK 560
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE-RSGTAQQKL---LEAQQS 423
+ + +L+ L+ ++++ + L + +E L+ ++E +QKL + +Q
Sbjct: 561 VTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQV 620
Query: 424 ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADG---KSDEVSRKLAFV 582
DE N + LE ++ + +++ L Q+ + + ED+ G ++EV RKL
Sbjct: 621 EDEKNSFREQLEEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKL--- 677
Query: 583 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
+ +LE R + A +LE+ + L L V + Q
Sbjct: 678 QKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQ 721
Score = 45.6 bits (103), Expect = 2e-04
Identities = 48/227 (21%), Positives = 101/227 (44%), Gaps = 24/227 (10%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 222
++ A +A +K+ +A+ L + + AM++ E+ + E + ++ K + +
Sbjct: 750 ERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHE 809
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 390
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E+S
Sbjct: 810 LEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEE 869
Query: 391 AQQKL------LEAQQSADENNRMCKV------------LENRAQQDEERMDQLTNQLKE 516
+++L +EA+ + R V LE + D+ QL++
Sbjct: 870 KKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK 929
Query: 517 ARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 657
+ +D + D+ + + + E ++KS +A++ +L+EEL
Sbjct: 930 LQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEEL 976
Score = 45.6 bits (103), Expect = 2e-04
Identities = 50/240 (20%), Positives = 110/240 (45%), Gaps = 19/240 (7%)
Frame = +1
Query: 61 ATMDA---IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNE---EVRELQKKLA- 219
AT DA ++ +QAMK + + + D ++ + +R + E E Q+ +A
Sbjct: 837 ATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAV 896
Query: 220 ----QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK--SEER 381
++E DL + ++ ANK+ +E KQL +A++ R++ E+ ++ +
Sbjct: 897 AARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAK 956
Query: 382 SGTAQQKLLEAQQ-SADENNRMCKVLENRAQQD-EERMDQLTNQLKEARLLAED---ADG 546
+ K +EA+ E + + +AQQ+ +E D++ N + L E+ +
Sbjct: 957 ENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEA 1016
Query: 547 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV-GNSLKSLEVSEEKANQRVE 723
+ ++ +L + E+ DR+K + +I ++ +L + G++ K+ ++ Q E
Sbjct: 1017 RIAQLEEELEEEQGNTELINDRLKKANLQIDQINADLNLERGHAQKNENARQQLERQNKE 1076
Score = 43.2 bits (97), Expect = 0.001
Identities = 55/245 (22%), Positives = 112/245 (45%), Gaps = 26/245 (10%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMD--KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED 234
A + ++ ++ A K E + +A E++ R +L+AEK +++Q+ + ++EE
Sbjct: 183 AEAEELRARLTAKKQELEEICHDLEARVEEEEERYQHLQAEK-----KKMQQNIQELEEQ 237
Query: 235 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 414
L ++ ++ + E +L E E L + ++ ++ + E+R L E
Sbjct: 238 LEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEE 297
Query: 415 QQSA-------DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR-- 567
++ + +++ M LE R +++E++ +L K R L D+ SD+++
Sbjct: 298 EEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELE---KTRRKLEGDSTDLSDQIAELQ 354
Query: 568 --------KLAFVEDELEVAEDRVKSGDA-------KISELEEELKVVGNSLKSLEVSEE 702
+LA E+EL+ A RV+ A KI ELE ++ + L+S S
Sbjct: 355 AQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRN 414
Query: 703 KANQR 717
KA ++
Sbjct: 415 KAEKQ 419
Score = 31.9 bits (69), Expect = 2.4
Identities = 36/183 (19%), Positives = 83/183 (45%), Gaps = 18/183 (9%)
Frame = +1
Query: 166 LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 345
L+ + EE+ +++L +V E + +N+L ++E + QL A + ++ +
Sbjct: 124 LQVSRQEEEMMAKEEELVKVREKQLAAENRL----MEMETLQSQLMAEKLQLQEQLQAET 179
Query: 346 QIEEDLEKSEERSGTAQQKL------LEAQQSADENNRMC-----KVLENRAQQDEERMD 492
++ + E+ R +Q+L LEA+ +E K ++ Q+ EE+++
Sbjct: 180 ELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERYQHLQAEKKKMQQNIQELEEQLE 239
Query: 493 QLTNQLKEARLLAEDADGKSDEVSRKLAFVED-------ELEVAEDRVKSGDAKISELEE 651
+ + ++ +L + K ++ + +ED E ++ EDR+ ++E EE
Sbjct: 240 EEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEE 299
Query: 652 ELK 660
+ K
Sbjct: 300 KSK 302
>CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein.
Length = 1960
Score = 59.7 bits (138), Expect = 1e-08
Identities = 43/193 (22%), Positives = 93/193 (48%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
Q RD R E+ E+ ++L +++ ++E +L + + A ++ E L EA +
Sbjct: 1568 QFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHID 1627
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
+ N+ + + L K + + ++L + + S +E K E + + E M QL
Sbjct: 1628 SANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQE 1687
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 684
+L A A + DE++ ++A + +A + + +A+I++LEEEL+ + +
Sbjct: 1688 ELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTEL 1747
Query: 685 LEVSEEKANQRVE 723
+ +KAN +++
Sbjct: 1748 INDRLKKANLQID 1760
Score = 55.6 bits (128), Expect = 2e-07
Identities = 47/189 (24%), Positives = 83/189 (43%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
E Q +D ++ N + L KL QVE++ + +LE+ + EKQ+ A+V
Sbjct: 1307 ESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQV 1366
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
A + +K++ LE +EE Q+ L Q +E LE + ++ +D L
Sbjct: 1367 ADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLL 1426
Query: 502 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 681
L R A + + K + + LA E++ A+ + A+ E+E K + +
Sbjct: 1427 VDLDHQRQSACNLEKKQKKFDQLLA--EEKTISAKYAEERDRAEAEAREKETKALSLARA 1484
Query: 682 SLEVSEEKA 708
E E+KA
Sbjct: 1485 LEEAMEQKA 1493
Score = 53.6 bits (123), Expect = 7e-07
Identities = 56/236 (23%), Positives = 111/236 (47%), Gaps = 23/236 (9%)
Frame = +1
Query: 73 AIKKKMQAMK-LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 249
A K + +A+K L K A K C ++ D E++ + +E +KKL +E ++I +
Sbjct: 1629 ANKNRDEAIKQLRKLQAQMK--DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQ 1686
Query: 250 NKL---EQANKDLEEKEKQLTATEA-----------EVAALNRKVQQIEEDLEKSEERSG 387
+L E+A + +++ +L A E L ++ Q+EE+LE+ + +
Sbjct: 1687 EELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTE 1746
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG--KS--- 552
+L +A D+ N + + AQ++E QL Q KE ++ ++ +G KS
Sbjct: 1747 LINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYK 1806
Query: 553 ---DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
+ K+A +E++L+ ++ ++ E++LK V L+V +E+ N
Sbjct: 1807 ASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDV-----LLQVDDERRN 1857
Score = 51.2 bits (117), Expect = 4e-06
Identities = 52/229 (22%), Positives = 107/229 (46%), Gaps = 4/229 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE----KVNEEVRELQKKL 216
++K+ ++ +K K +AM + + + + + Q+ + E +++++ ELQ ++
Sbjct: 1012 EEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQI 1071
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 396
A+++ L + +L+ A +EE+ Q ++ L ++ +++EDLE SE S
Sbjct: 1072 AELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLE-SERASRNKA 1130
Query: 397 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLA 576
+K Q D + + LE + E+ +D Q +E R E EV+
Sbjct: 1131 EK-----QKRD----LGEELEALKTELEDTLDSTAAQ-QELRSKREQ------EVNILKK 1174
Query: 577 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+E+E + E +++ K S+ EEL K ++ + EKA Q +E
Sbjct: 1175 TLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLE 1223
Score = 49.6 bits (113), Expect = 1e-05
Identities = 45/189 (23%), Positives = 90/189 (47%), Gaps = 5/189 (2%)
Frame = +1
Query: 172 AEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTAT--EAEVAALNRKVQ 345
AE+V ++++ + L+Q E+ + +KLE+ L+++ L +A N + +
Sbjct: 1383 AEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKK 1442
Query: 346 QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQ---LTNQLKE 516
Q + D +EE++ +A+ + A+ + K L + A+ EE M+Q L K+
Sbjct: 1443 QKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKAL-SLARALEEAMEQKAELERLNKQ 1501
Query: 517 ARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVS 696
R ED D+V + + +E E +V+ ++ ELE+EL+ ++ LEV+
Sbjct: 1502 FRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVN 1561
Query: 697 EEKANQRVE 723
+ + E
Sbjct: 1562 LQAMKAQFE 1570
Score = 47.6 bits (108), Expect = 4e-05
Identities = 46/229 (20%), Positives = 104/229 (45%), Gaps = 11/229 (4%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
++ + + + KLE++ + + C+ A++ L +++ E L ++ + + L
Sbjct: 964 LEKVTTEAKLKKLEEEQIILEDQNCKL-AKEKKLLEDRIAEFTTNLTEE-EEKSKSLAKL 1021
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK--SEERSGTAQQKLLEAQQ 420
KNK E DLEE+ ++ E+ RK++ DL +E ++ A+ K+ A++
Sbjct: 1022 KNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKK 1081
Query: 421 SADENNRMCKVLENRAQQD---------EERMDQLTNQLKEARLLAEDADGKSDEVSRKL 573
+ + +V E AQ++ E ++ +L L+ R A+ + ++ +L
Sbjct: 1082 EEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEEL 1141
Query: 574 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
++ ELE D + S+ E+E+ ++ +L+ + E Q +
Sbjct: 1142 EALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEM 1190
Score = 45.6 bits (103), Expect = 2e-04
Identities = 48/227 (21%), Positives = 101/227 (44%), Gaps = 24/227 (10%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 222
++ A +A +K+ +A+ L + + AM++ E+ + E + ++ K + +
Sbjct: 1463 ERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHE 1522
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 390
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E+S
Sbjct: 1523 LEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEE 1582
Query: 391 AQQKL------LEAQQSADENNRMCKV------------LENRAQQDEERMDQLTNQLKE 516
+++L +EA+ + R V LE + D+ QL++
Sbjct: 1583 KKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK 1642
Query: 517 ARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 657
+ +D + D+ + + + E ++KS +A++ +L+EEL
Sbjct: 1643 LQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEEL 1689
Score = 45.6 bits (103), Expect = 2e-04
Identities = 52/239 (21%), Positives = 109/239 (45%), Gaps = 18/239 (7%)
Frame = +1
Query: 61 ATMDA---IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNE---EVRELQKKLA- 219
AT DA ++ +QAMK + + + D ++ + +R + E E Q+ +A
Sbjct: 1550 ATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAV 1609
Query: 220 ----QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK--SEER 381
++E DL + ++ ANK+ +E KQL +A++ R++ E+ ++ +
Sbjct: 1610 AARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAK 1669
Query: 382 SGTAQQKLLEAQQ-SADENNRMCKVLENRAQQD-EERMDQLTNQLKEARLLAED---ADG 546
+ K +EA+ E + + +AQQ+ +E D++ N + L E+ +
Sbjct: 1670 ENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEA 1729
Query: 547 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ ++ +L + E+ DR+K + +I ++ +L N +S E A Q++E
Sbjct: 1730 RIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDL----NLERSHAQKNENARQQLE 1784
Score = 43.2 bits (97), Expect = 0.001
Identities = 55/245 (22%), Positives = 112/245 (45%), Gaps = 26/245 (10%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMD--KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED 234
A + ++ ++ A K E + +A E++ R +L+AEK +++Q+ + ++EE
Sbjct: 897 AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEK-----KKMQQNIQELEEQ 951
Query: 235 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 414
L ++ ++ + E +L E E L + ++ ++ + E+R L E
Sbjct: 952 LEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEE 1011
Query: 415 QQSA-------DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR-- 567
++ + +++ M LE R +++E++ +L K R L D+ SD+++
Sbjct: 1012 EEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELE---KTRRKLEGDSTDLSDQIAELQ 1068
Query: 568 --------KLAFVEDELEVAEDRVKSGDA-------KISELEEELKVVGNSLKSLEVSEE 702
+LA E+EL+ A RV+ A KI ELE ++ + L+S S
Sbjct: 1069 AQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRN 1128
Query: 703 KANQR 717
KA ++
Sbjct: 1129 KAEKQ 1133
Score = 40.3 bits (90), Expect = 0.007
Identities = 41/225 (18%), Positives = 98/225 (43%), Gaps = 8/225 (3%)
Frame = +1
Query: 73 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 252
++ K++ ++ EK++ ++ + E+ + + ++ +V +++KK+ L +
Sbjct: 1326 SLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEE 1385
Query: 253 KLEQANKDLE----EKEKQLTATEAEVAALNRKVQQIEE---DLEKSEERSGTAQQKLLE 411
+ KDLE E+++ A + R Q++++ DL+ + + ++K +
Sbjct: 1386 VKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKK 1445
Query: 412 AQQ-SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
Q A+E K E R + + E ++ T L AR L E + K+ E+ R
Sbjct: 1446 FDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKA-ELERLNKQFRT 1504
Query: 589 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
E+E + ELE+ + + ++ ++ E+ ++
Sbjct: 1505 EMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQ 1549
Score = 33.1 bits (72), Expect = 1.0
Identities = 35/183 (19%), Positives = 82/183 (44%), Gaps = 18/183 (9%)
Frame = +1
Query: 166 LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 345
L+ + EE+ +++L +V E + +N+L + +E + QL A + ++ +
Sbjct: 838 LQVSRQEEEMMAKEEELVKVREKQLAAENRLTE----METLQSQLMAEKLQLQEQLQAET 893
Query: 346 QIEEDLEKSEERSGTAQQKLLEA----QQSADENNRMC-------KVLENRAQQDEERMD 492
++ + E+ R +Q+L E + +E C K ++ Q+ EE+++
Sbjct: 894 ELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLE 953
Query: 493 QLTNQLKEARLLAEDADGKSDEVSRKLAFVED-------ELEVAEDRVKSGDAKISELEE 651
+ + ++ +L + K ++ + +ED E ++ EDR+ ++E EE
Sbjct: 954 EEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEE 1013
Query: 652 ELK 660
+ K
Sbjct: 1014 KSK 1016
>AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein
protein.
Length = 1331
Score = 59.7 bits (138), Expect = 1e-08
Identities = 43/193 (22%), Positives = 93/193 (48%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
Q RD R E+ E+ ++L +++ ++E +L + + A ++ E L EA +
Sbjct: 990 QFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHID 1049
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
+ N+ + + L K + + ++L + + S +E K E + + E M QL
Sbjct: 1050 SANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQE 1109
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 684
+L A A + DE++ ++A + +A + + +A+I++LEEEL+ + +
Sbjct: 1110 ELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTEL 1169
Query: 685 LEVSEEKANQRVE 723
+ +KAN +++
Sbjct: 1170 INDRLKKANLQID 1182
Score = 54.8 bits (126), Expect = 3e-07
Identities = 55/225 (24%), Positives = 107/225 (47%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+++ + A KKKMQ E + +++ ++ Q+ L+ EKV E + KKL +
Sbjct: 792 EERCQHLQAEKKKMQQNIQELEEQLEEEESARQK-----LQLEKVTTEAK--LKKLEEEL 844
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
+DL+++ + Q+ +LE+K+K+ AE ++ K E D ++E R + K L
Sbjct: 845 DDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAG-ERDRAEAEARE--KETKAL 901
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
++ +E +E +A+ ER++ K+ R ED D+V + + +E
Sbjct: 902 SLARALEE------AMEQKAEL--ERLN------KQFRTEMEDLMSSKDDVGKSVHELEK 947
Query: 589 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
E +V+ ++ ELE EL+ ++ LEV+ + + E
Sbjct: 948 SKRALEQQVEEMKTQLEELEGELQATEDAKLRLEVNLQAMKAQFE 992
Score = 53.6 bits (123), Expect = 7e-07
Identities = 56/236 (23%), Positives = 111/236 (47%), Gaps = 23/236 (9%)
Frame = +1
Query: 73 AIKKKMQAMK-LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 249
A K + +A+K L K A K C ++ D E++ + +E +KKL +E ++I +
Sbjct: 1051 ANKNRDEAIKQLRKLQAQMK--DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQ 1108
Query: 250 NKL---EQANKDLEEKEKQLTATEA-----------EVAALNRKVQQIEEDLEKSEERSG 387
+L E+A + +++ +L A E L ++ Q+EE+LE+ + +
Sbjct: 1109 EELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTE 1168
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG--KS--- 552
+L +A D+ N + + AQ++E QL Q KE ++ ++ +G KS
Sbjct: 1169 LINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYK 1228
Query: 553 ---DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
+ K+A +E++L+ ++ ++ E++LK V L+V +E+ N
Sbjct: 1229 ASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDV-----LLQVDDERRN 1279
Score = 48.0 bits (109), Expect = 3e-05
Identities = 38/194 (19%), Positives = 84/194 (43%), Gaps = 1/194 (0%)
Frame = +1
Query: 127 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTA 306
K E+ D R E+ E + LQ + ++++++ + +LE+ ++ + +
Sbjct: 773 KKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVT 832
Query: 307 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADENNRMCKVLENRAQQDEE 483
TEA++ L ++ + DL+ + + ++K + Q A+E K R + + E
Sbjct: 833 TEAKLKKLEEELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAGERDRAEAE 892
Query: 484 RMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKV 663
++ T L AR L E + K+ E+ R E+E + ELE+ +
Sbjct: 893 AREKETKALSLARALEEAMEQKA-ELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRA 951
Query: 664 VGNSLKSLEVSEEK 705
+ ++ ++ E+
Sbjct: 952 LEQQVEEMKTQLEE 965
Score = 45.6 bits (103), Expect = 2e-04
Identities = 52/239 (21%), Positives = 109/239 (45%), Gaps = 18/239 (7%)
Frame = +1
Query: 61 ATMDA---IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNE---EVRELQKKLA- 219
AT DA ++ +QAMK + + + D ++ + +R + E E Q+ +A
Sbjct: 972 ATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAV 1031
Query: 220 ----QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK--SEER 381
++E DL + ++ ANK+ +E KQL +A++ R++ E+ ++ +
Sbjct: 1032 AARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAK 1091
Query: 382 SGTAQQKLLEAQQ-SADENNRMCKVLENRAQQD-EERMDQLTNQLKEARLLAED---ADG 546
+ K +EA+ E + + +AQQ+ +E D++ N + L E+ +
Sbjct: 1092 ENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEA 1151
Query: 547 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ ++ +L + E+ DR+K + +I ++ +L N +S E A Q++E
Sbjct: 1152 RIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDL----NLERSHAQKNENARQQLE 1206
Score = 45.2 bits (102), Expect = 2e-04
Identities = 48/227 (21%), Positives = 101/227 (44%), Gaps = 24/227 (10%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 222
++ A +A +K+ +A+ L + + AM++ E+ + E + ++ K + +
Sbjct: 885 ERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHE 944
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 390
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E+S
Sbjct: 945 LEKSKRALEQQVEEMKTQLEELEGELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEE 1004
Query: 391 AQQKL------LEAQQSADENNRMCKV------------LENRAQQDEERMDQLTNQLKE 516
+++L +EA+ + R V LE + D+ QL++
Sbjct: 1005 KKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK 1064
Query: 517 ARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 657
+ +D + D+ + + + E ++KS +A++ +L+EEL
Sbjct: 1065 LQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEEL 1111
>AK131080-1|BAC85130.1| 563|Homo sapiens FLJ00279 protein protein.
Length = 563
Score = 59.7 bits (138), Expect = 1e-08
Identities = 43/193 (22%), Positives = 93/193 (48%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
Q RD R E+ E+ ++L +++ ++E +L + + A ++ E L EA +
Sbjct: 171 QFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHID 230
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
+ N+ + + L K + + ++L + + S +E K E + + E M QL
Sbjct: 231 SANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQE 290
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 684
+L A A + DE++ ++A + +A + + +A+I++LEEEL+ + +
Sbjct: 291 ELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTEL 350
Query: 685 LEVSEEKANQRVE 723
+ +KAN +++
Sbjct: 351 INDRLKKANLQID 363
Score = 53.6 bits (123), Expect = 7e-07
Identities = 56/236 (23%), Positives = 111/236 (47%), Gaps = 23/236 (9%)
Frame = +1
Query: 73 AIKKKMQAMK-LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 249
A K + +A+K L K A K C ++ D E++ + +E +KKL +E ++I +
Sbjct: 232 ANKNRDEAIKQLRKLQAQMK--DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQ 289
Query: 250 NKL---EQANKDLEEKEKQLTATEA-----------EVAALNRKVQQIEEDLEKSEERSG 387
+L E+A + +++ +L A E L ++ Q+EE+LE+ + +
Sbjct: 290 EELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTE 349
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG--KS--- 552
+L +A D+ N + + AQ++E QL Q KE ++ ++ +G KS
Sbjct: 350 LINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYK 409
Query: 553 ---DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
+ K+A +E++L+ ++ ++ E++LK V L+V +E+ N
Sbjct: 410 ASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDV-----LLQVDDERRN 460
Score = 45.6 bits (103), Expect = 2e-04
Identities = 52/239 (21%), Positives = 109/239 (45%), Gaps = 18/239 (7%)
Frame = +1
Query: 61 ATMDA---IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNE---EVRELQKKLA- 219
AT DA ++ +QAMK + + + D ++ + +R + E E Q+ +A
Sbjct: 153 ATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAV 212
Query: 220 ----QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK--SEER 381
++E DL + ++ ANK+ +E KQL +A++ R++ E+ ++ +
Sbjct: 213 AARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAK 272
Query: 382 SGTAQQKLLEAQQ-SADENNRMCKVLENRAQQD-EERMDQLTNQLKEARLLAED---ADG 546
+ K +EA+ E + + +AQQ+ +E D++ N + L E+ +
Sbjct: 273 ENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEA 332
Query: 547 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ ++ +L + E+ DR+K + +I ++ +L N +S E A Q++E
Sbjct: 333 RIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDL----NLERSHAQKNENARQQLE 387
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/204 (21%), Positives = 88/204 (43%), Gaps = 22/204 (10%)
Frame = +1
Query: 112 DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKE 291
+ AM++ E+ + E + ++ K + ++E+ + ++E+ LEE E
Sbjct: 89 EEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELE 148
Query: 292 KQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGTAQQKL------LEAQQSADENNR 441
+L ATE L +Q Q E DL+ +E+S +++L +EA+ + R
Sbjct: 149 DELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQR 208
Query: 442 MCKV------------LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
V LE + D+ QL++ + +D + D+ +
Sbjct: 209 SMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEIL 268
Query: 586 DELEVAEDRVKSGDAKISELEEEL 657
+ + E ++KS +A++ +L+EEL
Sbjct: 269 AQAKENEKKLKSMEAEMIQLQEEL 292
Score = 33.9 bits (74), Expect = 0.59
Identities = 23/85 (27%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +1
Query: 478 EERMDQ---LTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE 648
EE M+Q L K+ R ED D+V + + +E E +V+ ++ ELE
Sbjct: 89 EEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELE 148
Query: 649 EELKVVGNSLKSLEVSEEKANQRVE 723
+EL+ ++ LEV+ + + E
Sbjct: 149 DELQATEDAKLRLEVNLQAMKAQFE 173
>AK092490-1|BAC03904.1| 280|Homo sapiens protein ( Homo sapiens
cDNA FLJ35171 fis, clone PLACE6013220, weakly similar to
TRICHOHYALIN. ).
Length = 280
Score = 59.7 bits (138), Expect = 1e-08
Identities = 42/187 (22%), Positives = 91/187 (48%)
Frame = +1
Query: 163 NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 342
+L + E +RE +++L + EE +++L + + L E+E++L E + ++
Sbjct: 3 SLLNRRQEERLREQEERLREQEERQREQEDRLHEQEERLREQEERLCEQEERLCEQEERL 62
Query: 343 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 522
++ EE L + EER +++L E ++ E + E R + EER+ + +L E
Sbjct: 63 REHEERLCEQEERLCEQEERLREQEERLHEQEERLREQEERLCEQEERLREHEERLCEQE 122
Query: 523 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 702
+ + + E +L E+ L E+R++ + ++ E +E+L L+ +E E
Sbjct: 123 ERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCE-QEKLPGQERLLEEVEKLLE 181
Query: 703 KANQRVE 723
+ ++ E
Sbjct: 182 QERRQEE 188
Score = 57.6 bits (133), Expect = 4e-08
Identities = 43/188 (22%), Positives = 90/188 (47%), Gaps = 1/188 (0%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
E++ R+ R + + + E +++L + EE L + +L + + L E E++L E +
Sbjct: 17 EERLREQEERQREQEDRLHEQEERLREQEERLCEQEERLCEQEERLREHEERLCEQEERL 76
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN-RMCKVLENRAQQDEERMDQL 498
++++ EE L + EER +++L E ++ E+ R+C+ E R ++ EER+ +
Sbjct: 77 CEQEERLREQEERLHEQEERLREQEERLCEQEERLREHEERLCEQ-EERLREQEERLCEQ 135
Query: 499 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL 678
+L+E + + + E +L E E ++R+ K+ E E + L
Sbjct: 136 EERLREQEERLCEQEERLREQEERLC--EQEKLPGQERLLEEVEKLLEQERRQEEQERLL 193
Query: 679 KSLEVSEE 702
+ + EE
Sbjct: 194 ERERLLEE 201
Score = 54.4 bits (125), Expect = 4e-07
Identities = 41/172 (23%), Positives = 78/172 (45%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
E++ R+ R + E RE + +L + EE L + +L + + L E+E++L E +
Sbjct: 10 EERLREQEERLREQEERQREQEDRLHEQEERLREQEERLCEQEERLCEQEERLREHEERL 69
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
++ + EE L + EER +++L E ++ E + E R + EER+ +
Sbjct: 70 CEQEERLCEQEERLREQEERLHEQEERLREQEERLCEQEERLREHEERLCEQEERLREQE 129
Query: 502 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 657
+L E + + + E +L E E + E G ++ E E+L
Sbjct: 130 ERLCEQEERLREQEERLCEQEERLR--EQEERLCEQEKLPGQERLLEEVEKL 179
Score = 52.0 bits (119), Expect = 2e-06
Identities = 40/179 (22%), Positives = 86/179 (48%)
Frame = +1
Query: 124 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 303
D+ E++ R+ R + E + E +++L + EE L + +L + + L E+E++L
Sbjct: 32 DRLHEQEERLREQEERLCEQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLH 91
Query: 304 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE 483
E + ++ + EE L + EER +++L E ++ E + E R + EE
Sbjct: 92 EQEERLREQEERLCEQEERLREHEERLCEQEERLREQEERLCEQEERLREQEERLCEQEE 151
Query: 484 RMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 660
R+ + +L E L + +EV + L ++ + ++R+ + + E+E+ L+
Sbjct: 152 RLREQEERLCEQEKL-PGQERLLEEVEKLLE--QERRQEEQERLLERERLLEEVEKLLE 207
Score = 43.2 bits (97), Expect = 0.001
Identities = 32/117 (27%), Positives = 63/117 (53%), Gaps = 1/117 (0%)
Frame = +1
Query: 139 CEQQARDANLRAEKVNEEVREL-QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 315
CEQ+ E++ EEV +L +++ Q E++ +L + +L + + L E+E+Q E
Sbjct: 161 CEQEKLPGQ---ERLLEEVEKLLEQERRQEEQERLLERERLLEEVEKLLEQERQQEEQE- 216
Query: 316 EVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 486
+ R ++++E+ LE +ER Q++LLE ++ DE + +E +Q+ R
Sbjct: 217 RLLERERLLEEVEKLLE--QERRQEEQERLLERERLLDEVEELLDEVEELLEQERLR 271
>AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy
polypeptide 9 protein.
Length = 1960
Score = 59.7 bits (138), Expect = 1e-08
Identities = 43/193 (22%), Positives = 93/193 (48%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
Q RD R E+ E+ ++L +++ ++E +L + + A ++ E L EA +
Sbjct: 1568 QFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHID 1627
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
+ N+ + + L K + + ++L + + S +E K E + + E M QL
Sbjct: 1628 SANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQE 1687
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 684
+L A A + DE++ ++A + +A + + +A+I++LEEEL+ + +
Sbjct: 1688 ELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTEL 1747
Query: 685 LEVSEEKANQRVE 723
+ +KAN +++
Sbjct: 1748 INDRLKKANLQID 1760
Score = 55.6 bits (128), Expect = 2e-07
Identities = 47/189 (24%), Positives = 83/189 (43%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
E Q +D ++ N + L KL QVE++ + +LE+ + EKQ+ A+V
Sbjct: 1307 ESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQV 1366
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
A + +K++ LE +EE Q+ L Q +E LE + ++ +D L
Sbjct: 1367 ADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLL 1426
Query: 502 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 681
L R A + + K + + LA E++ A+ + A+ E+E K + +
Sbjct: 1427 VDLDHQRQSACNLEKKQKKFDQLLA--EEKTISAKYAEERDRAEAEAREKETKALSLARA 1484
Query: 682 SLEVSEEKA 708
E E+KA
Sbjct: 1485 LEEAMEQKA 1493
Score = 53.6 bits (123), Expect = 7e-07
Identities = 56/236 (23%), Positives = 111/236 (47%), Gaps = 23/236 (9%)
Frame = +1
Query: 73 AIKKKMQAMK-LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 249
A K + +A+K L K A K C ++ D E++ + +E +KKL +E ++I +
Sbjct: 1629 ANKNRDEAIKQLRKLQAQMK--DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQ 1686
Query: 250 NKL---EQANKDLEEKEKQLTATEA-----------EVAALNRKVQQIEEDLEKSEERSG 387
+L E+A + +++ +L A E L ++ Q+EE+LE+ + +
Sbjct: 1687 EELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTE 1746
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG--KS--- 552
+L +A D+ N + + AQ++E QL Q KE ++ ++ +G KS
Sbjct: 1747 LINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYK 1806
Query: 553 ---DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
+ K+A +E++L+ ++ ++ E++LK V L+V +E+ N
Sbjct: 1807 ASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDV-----LLQVDDERRN 1857
Score = 51.2 bits (117), Expect = 4e-06
Identities = 52/229 (22%), Positives = 107/229 (46%), Gaps = 4/229 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE----KVNEEVRELQKKL 216
++K+ ++ +K K +AM + + + + + Q+ + E +++++ ELQ ++
Sbjct: 1012 EEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQI 1071
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 396
A+++ L + +L+ A +EE+ Q ++ L ++ +++EDLE SE S
Sbjct: 1072 AELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLE-SERASRNKA 1130
Query: 397 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLA 576
+K Q D + + LE + E+ +D Q +E R E EV+
Sbjct: 1131 EK-----QKRD----LGEELEALKTELEDTLDSTAAQ-QELRSKREQ------EVNILKK 1174
Query: 577 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+E+E + E +++ K S+ EEL K ++ + EKA Q +E
Sbjct: 1175 TLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLE 1223
Score = 49.6 bits (113), Expect = 1e-05
Identities = 45/189 (23%), Positives = 90/189 (47%), Gaps = 5/189 (2%)
Frame = +1
Query: 172 AEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTAT--EAEVAALNRKVQ 345
AE+V ++++ + L+Q E+ + +KLE+ L+++ L +A N + +
Sbjct: 1383 AEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKK 1442
Query: 346 QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQ---LTNQLKE 516
Q + D +EE++ +A+ + A+ + K L + A+ EE M+Q L K+
Sbjct: 1443 QKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKAL-SLARALEEAMEQKAELERLNKQ 1501
Query: 517 ARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVS 696
R ED D+V + + +E E +V+ ++ ELE+EL+ ++ LEV+
Sbjct: 1502 FRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVN 1561
Query: 697 EEKANQRVE 723
+ + E
Sbjct: 1562 LQAMKAQFE 1570
Score = 47.6 bits (108), Expect = 4e-05
Identities = 46/229 (20%), Positives = 104/229 (45%), Gaps = 11/229 (4%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
++ + + + KLE++ + + C+ A++ L +++ E L ++ + + L
Sbjct: 964 LEKVTTEAKLKKLEEEQIILEDQNCKL-AKEKKLLEDRIAEFTTNLTEE-EEKSKSLAKL 1021
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK--SEERSGTAQQKLLEAQQ 420
KNK E DLEE+ ++ E+ RK++ DL +E ++ A+ K+ A++
Sbjct: 1022 KNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKK 1081
Query: 421 SADENNRMCKVLENRAQQD---------EERMDQLTNQLKEARLLAEDADGKSDEVSRKL 573
+ + +V E AQ++ E ++ +L L+ R A+ + ++ +L
Sbjct: 1082 EEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEEL 1141
Query: 574 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
++ ELE D + S+ E+E+ ++ +L+ + E Q +
Sbjct: 1142 EALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEM 1190
Score = 45.6 bits (103), Expect = 2e-04
Identities = 48/227 (21%), Positives = 101/227 (44%), Gaps = 24/227 (10%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 222
++ A +A +K+ +A+ L + + AM++ E+ + E + ++ K + +
Sbjct: 1463 ERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHE 1522
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 390
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E+S
Sbjct: 1523 LEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEE 1582
Query: 391 AQQKL------LEAQQSADENNRMCKV------------LENRAQQDEERMDQLTNQLKE 516
+++L +EA+ + R V LE + D+ QL++
Sbjct: 1583 KKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK 1642
Query: 517 ARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 657
+ +D + D+ + + + E ++KS +A++ +L+EEL
Sbjct: 1643 LQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEEL 1689
Score = 45.6 bits (103), Expect = 2e-04
Identities = 52/239 (21%), Positives = 109/239 (45%), Gaps = 18/239 (7%)
Frame = +1
Query: 61 ATMDA---IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNE---EVRELQKKLA- 219
AT DA ++ +QAMK + + + D ++ + +R + E E Q+ +A
Sbjct: 1550 ATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAV 1609
Query: 220 ----QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK--SEER 381
++E DL + ++ ANK+ +E KQL +A++ R++ E+ ++ +
Sbjct: 1610 AARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAK 1669
Query: 382 SGTAQQKLLEAQQ-SADENNRMCKVLENRAQQD-EERMDQLTNQLKEARLLAED---ADG 546
+ K +EA+ E + + +AQQ+ +E D++ N + L E+ +
Sbjct: 1670 ENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEA 1729
Query: 547 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ ++ +L + E+ DR+K + +I ++ +L N +S E A Q++E
Sbjct: 1730 RIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDL----NLERSHAQKNENARQQLE 1784
Score = 43.2 bits (97), Expect = 0.001
Identities = 55/245 (22%), Positives = 112/245 (45%), Gaps = 26/245 (10%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMD--KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED 234
A + ++ ++ A K E + +A E++ R +L+AEK +++Q+ + ++EE
Sbjct: 897 AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEK-----KKMQQNIQELEEQ 951
Query: 235 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 414
L ++ ++ + E +L E E L + ++ ++ + E+R L E
Sbjct: 952 LEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEE 1011
Query: 415 QQSA-------DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR-- 567
++ + +++ M LE R +++E++ +L K R L D+ SD+++
Sbjct: 1012 EEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELE---KTRRKLEGDSTDLSDQIAELQ 1068
Query: 568 --------KLAFVEDELEVAEDRVKSGDA-------KISELEEELKVVGNSLKSLEVSEE 702
+LA E+EL+ A RV+ A KI ELE ++ + L+S S
Sbjct: 1069 AQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRN 1128
Query: 703 KANQR 717
KA ++
Sbjct: 1129 KAEKQ 1133
Score = 40.3 bits (90), Expect = 0.007
Identities = 41/225 (18%), Positives = 98/225 (43%), Gaps = 8/225 (3%)
Frame = +1
Query: 73 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 252
++ K++ ++ EK++ ++ + E+ + + ++ +V +++KK+ L +
Sbjct: 1326 SLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEE 1385
Query: 253 KLEQANKDLE----EKEKQLTATEAEVAALNRKVQQIEE---DLEKSEERSGTAQQKLLE 411
+ KDLE E+++ A + R Q++++ DL+ + + ++K +
Sbjct: 1386 VKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKK 1445
Query: 412 AQQ-SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
Q A+E K E R + + E ++ T L AR L E + K+ E+ R
Sbjct: 1446 FDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKA-ELERLNKQFRT 1504
Query: 589 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
E+E + ELE+ + + ++ ++ E+ ++
Sbjct: 1505 EMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQ 1549
Score = 33.1 bits (72), Expect = 1.0
Identities = 35/183 (19%), Positives = 82/183 (44%), Gaps = 18/183 (9%)
Frame = +1
Query: 166 LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 345
L+ + EE+ +++L +V E + +N+L + +E + QL A + ++ +
Sbjct: 838 LQVSRQEEEMMAKEEELVKVREKQLAAENRLTE----METLQSQLMAEKLQLQEQLQAET 893
Query: 346 QIEEDLEKSEERSGTAQQKLLEA----QQSADENNRMC-------KVLENRAQQDEERMD 492
++ + E+ R +Q+L E + +E C K ++ Q+ EE+++
Sbjct: 894 ELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLE 953
Query: 493 QLTNQLKEARLLAEDADGKSDEVSRKLAFVED-------ELEVAEDRVKSGDAKISELEE 651
+ + ++ +L + K ++ + +ED E ++ EDR+ ++E EE
Sbjct: 954 EEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEE 1013
Query: 652 ELK 660
+ K
Sbjct: 1014 KSK 1016
>Z97054-3|CAI42646.1| 1233|Homo sapiens structural maintenance of
chromosomes 1A protein.
Length = 1233
Score = 58.4 bits (135), Expect = 2e-08
Identities = 42/165 (25%), Positives = 89/165 (53%), Gaps = 6/165 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQ-QARDANLRAEKVNEEVR---ELQKKL 216
+++ MD ++K+M +++ + ++ + Q Q RD L +V + R E K+
Sbjct: 327 KKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRA 386
Query: 217 AQVEEDLI-LNKN-KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 390
A + ++L N++ K +Q DLEE++K TEA++ R++++ ++ +EK EE T
Sbjct: 387 ATLAQELEKFNRDQKADQDRLDLEERKK--VETEAKIKQKLREIEENQKRIEKLEEYITT 444
Query: 391 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 525
++Q L E ++ E ++ + R + + ++Q+ QL +AR+
Sbjct: 445 SKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARI 489
Score = 49.6 bits (113), Expect = 1e-05
Identities = 45/212 (21%), Positives = 98/212 (46%), Gaps = 18/212 (8%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL-------EQANKDLEEKEKQL 300
E + N N+E+ + +K++ +VE++L K +L +Q K+++EK+ +L
Sbjct: 232 EVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSEL 291
Query: 301 TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDE 480
+ + LE +++ AQ+ + + DE + +E Q+ E
Sbjct: 292 NQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFE 351
Query: 481 ERMDQ--------LT---NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 627
ERM++ LT NQ+K+ L E+A ++ ++++L + + +DR+ +
Sbjct: 352 ERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEE 411
Query: 628 AKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
K E E ++K L+ +E ++++ + E
Sbjct: 412 RKKVETEAKIK---QKLREIEENQKRIEKLEE 440
Score = 44.8 bits (101), Expect = 3e-04
Identities = 38/204 (18%), Positives = 98/204 (48%), Gaps = 1/204 (0%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
K N + +Q+ +A+ R +++ +EV Q +L + L N+ ++E+ NK+L K
Sbjct: 189 KKNIAAERKEAKQEKEEAD-RYQRLKDEVVRAQVQLQLFK--LYHNEVEIEKLNKELASK 245
Query: 289 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN-RMCKVLENR 465
K++ + + + ++++ +++L K ++++ E ++ + K EN
Sbjct: 246 NKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENT 305
Query: 466 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
+ + ++++ L+ A+ + G DE+ +++ VE + E+R+ + +
Sbjct: 306 SHK-IKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERM---EEESQSQ 361
Query: 646 EEELKVVGNSLKSLEVSEEKANQR 717
+L + N +K +E+A++R
Sbjct: 362 GRDLTLEENQVKKYHRLKEEASKR 385
Score = 40.7 bits (91), Expect = 0.005
Identities = 37/203 (18%), Positives = 95/203 (46%), Gaps = 13/203 (6%)
Frame = +1
Query: 79 KKKMQAMKLEKDNA--MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 252
+K+ Q +K +++ + + K + ++ ++A +K ++ EL+K++ VE+ +
Sbjct: 293 QKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEE 352
Query: 253 KLEQAN----KDLEEKEKQL-------TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 399
++E+ + +DL +E Q+ A L +++++ D + ++R ++
Sbjct: 353 RMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEER 412
Query: 400 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 579
K +E + + R + + R ++ EE + L+E + L + + + R++
Sbjct: 413 KKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDE 472
Query: 580 VEDELEVAEDRVKSGDAKISELE 648
+ EL +++ GDA+I E
Sbjct: 473 INKELNQVMEQL--GDARIDRQE 493
Score = 40.7 bits (91), Expect = 0.005
Identities = 50/222 (22%), Positives = 96/222 (43%), Gaps = 7/222 (3%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-------VRELQKKLAQVEED 234
I+ + +L++D DK EQ + EK+ +E + E +L ++
Sbjct: 819 IQLDFEKNQLKEDQ--DKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQ 876
Query: 235 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 414
+ K+++ N ++EE K+L E+ L ++V IE LE ++RS + LL+A
Sbjct: 877 HLAKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLE--QKRSD--RHNLLQA 932
Query: 415 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 594
CK+ + + + MD ++ + E ED+ S +S + + L
Sbjct: 933 ----------CKMQDIKLPLSKGTMDDISQE--EGSSQGEDSVSGSQRISS--IYAREAL 978
Query: 595 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ D K ++ EEE+K N+L+ ++ QR+
Sbjct: 979 IEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRI 1020
Score = 37.5 bits (83), Expect = 0.048
Identities = 45/227 (19%), Positives = 98/227 (43%), Gaps = 11/227 (4%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQAR--DANLRAE-----KVNEEVRELQKKLAQV 225
MD ++ +++ K E M + E++ + D+ L + K E KKL
Sbjct: 256 MDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAA 315
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
++ L + ++ D++E EK++ + E + Q+ EE +E EE +
Sbjct: 316 KKSLQNAQKHYKKRKGDMDELEKEMLSVE-------KARQEFEERME--EESQSQGRDLT 366
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
LE Q + +R+ + RA + +++ K + + + K E K+
Sbjct: 367 LEENQ-VKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKL 425
Query: 586 DELEVAEDRVKSGDAKIS----ELEEELKVVGNSLKSLEVSEEKANQ 714
E+E + R++ + I+ LEE+ K+ G + +E+++ + ++
Sbjct: 426 REIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDE 472
Score = 32.7 bits (71), Expect = 1.4
Identities = 45/217 (20%), Positives = 89/217 (41%), Gaps = 21/217 (9%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL-------AQV 225
++ +KK+ Q D M + + Q N E+ E++KKL +
Sbjct: 849 IEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHL 908
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI--EEDLEKSEER-SGTAQ 396
++++ + KLEQ D + + ++ + I EE + E+ SG+ +
Sbjct: 909 QKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLSKGTMDDISQEEGSSQGEDSVSGSQR 968
Query: 397 QKLLEAQQSADE--NNRMCKVLENRAQQDE--ERMDQLTNQLKE-----ARLLAED--AD 543
+ A+++ E +C+ L++ ++E + M+ L +L E R+ A + A
Sbjct: 969 ISSIYAREALIEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRIAAPNMKAM 1028
Query: 544 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 654
K + V K DE E A R K ++++E
Sbjct: 1029 EKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKE 1065
>X64838-1|CAA46050.1| 1427|Homo sapiens restin protein.
Length = 1427
Score = 58.4 bits (135), Expect = 2e-08
Identities = 43/227 (18%), Positives = 102/227 (44%), Gaps = 8/227 (3%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
++A +K+++ +++EK+ KA + ++ + L+ + E + E+ + +E++L +
Sbjct: 786 LEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQIL 845
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
K K +A+++ ++ + T ++ + + DLEK E + K E +
Sbjct: 846 KEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDERE 905
Query: 427 DENNRMCKVLENR----AQQDEERMDQLTNQLKEARLLAEDADG---KSDEVSRKLAFVE 585
++ + + LEN + + QLT E RL D + K + + +F++
Sbjct: 906 EQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQ 965
Query: 586 DELEVAEDRVKSGDAKISEL-EEELKVVGNSLKSLEVSEEKANQRVE 723
+E + + + ++ EEE K + L LE E ++ + +
Sbjct: 966 KSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQ 1012
Score = 50.4 bits (115), Expect = 6e-06
Identities = 68/239 (28%), Positives = 104/239 (43%), Gaps = 20/239 (8%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR--------EL 204
QQ+AA +KK KL + K +T Q ++ R E+ E + L
Sbjct: 979 QQEAAKKHEEEKKELERKLS--DLEKKMETSHNQCQELKARYERATSETKTKHEEILQNL 1036
Query: 205 QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS 384
QK L E+ L + + ++LEE KQ A +A+ A QI E + K E++
Sbjct: 1037 QKTLLDTEDKLKGAREENSGLLQELEELRKQ--ADKAKAAQTAEDAMQIMEQMTK--EKT 1092
Query: 385 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEE---RMDQLT--NQ-----LKEARLLAE 534
T Q +A N + + EN + EE + LT NQ KE L +
Sbjct: 1093 ETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQ 1152
Query: 535 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKIS--ELEEELKVVGNSLKSLEVSEEK 705
A KS ++S A E+ +++AE+ +S D S +LEEE V+ N L ++ E K
Sbjct: 1153 AAAQKSQQLS---ALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESK 1208
Score = 40.3 bits (90), Expect = 0.007
Identities = 41/203 (20%), Positives = 91/203 (44%), Gaps = 4/203 (1%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED----LILNKNKLEQANKD 276
K++ + +T +++ + EK+++E L+ KL ++ + L K+KLE A
Sbjct: 563 KEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIAS 622
Query: 277 LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 456
++ ++L + ++ L + + E L+ E+ Q +E Q+ ++ R
Sbjct: 623 HQQAMEELKVSFSK--GLGTETAEFAE-LKTQIEKMRLDYQHEIENLQNQQDSERAAHAK 679
Query: 457 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 636
E A + + M + + + D D+ ++ ++L+ AE +VK +
Sbjct: 680 EMEALR-AKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQ 738
Query: 637 SELEEELKVVGNSLKSLEVSEEK 705
++ E+ KV+ N L+ +EEK
Sbjct: 739 AKCNEQTKVIDNFTSQLKATEEK 761
Score = 36.3 bits (80), Expect = 0.11
Identities = 49/210 (23%), Positives = 88/210 (41%)
Frame = +1
Query: 28 FNSTGP*QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQ 207
F ST P + KA + + A L++ + + A + R + + E
Sbjct: 283 FPSTTPAKAKANAVRRVMATTSA-SLKRSPSASSLSSMSSVASSVSSRPSRTGL-LTETS 340
Query: 208 KKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 387
+ A+ + L++ + +E+ + AEVA V +IE++L + R G
Sbjct: 341 SRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALA--RDG 398
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
Q +LE + D+ M + D E+++ L NQL+E + ED + +E S
Sbjct: 399 H-DQHVLELEAKMDQLRTMVEAA------DREKVE-LLNQLEEEKRKVEDLQFRVEEES- 449
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEEL 657
+ +LE + K A+I ELE+ L
Sbjct: 450 ---ITKGDLET---QTKLEHARIKELEQSL 473
>S78271-1|AAB34405.1| 1233|Homo sapiens SB1.8/DXS423E protein.
Length = 1233
Score = 58.4 bits (135), Expect = 2e-08
Identities = 42/165 (25%), Positives = 89/165 (53%), Gaps = 6/165 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQ-QARDANLRAEKVNEEVR---ELQKKL 216
+++ MD ++K+M +++ + ++ + Q Q RD L +V + R E K+
Sbjct: 327 KKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRA 386
Query: 217 AQVEEDLI-LNKN-KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 390
A + ++L N++ K +Q DLEE++K TEA++ R++++ ++ +EK EE T
Sbjct: 387 ATLAQELEKFNRDQKADQDRLDLEERKK--VETEAKIKQKLREIEENQKRIEKLEEYITT 444
Query: 391 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 525
++Q L E ++ E ++ + R + + ++Q+ QL +AR+
Sbjct: 445 SKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARI 489
Score = 49.6 bits (113), Expect = 1e-05
Identities = 45/212 (21%), Positives = 98/212 (46%), Gaps = 18/212 (8%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL-------EQANKDLEEKEKQL 300
E + N N+E+ + +K++ +VE++L K +L +Q K+++EK+ +L
Sbjct: 232 EVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSEL 291
Query: 301 TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDE 480
+ + LE +++ AQ+ + + DE + +E Q+ E
Sbjct: 292 NQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFE 351
Query: 481 ERMDQ--------LT---NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 627
ERM++ LT NQ+K+ L E+A ++ ++++L + + +DR+ +
Sbjct: 352 ERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEE 411
Query: 628 AKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
K E E ++K L+ +E ++++ + E
Sbjct: 412 RKKVETEAKIK---QKLREIEENQKRIEKLEE 440
Score = 44.8 bits (101), Expect = 3e-04
Identities = 38/204 (18%), Positives = 98/204 (48%), Gaps = 1/204 (0%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
K N + +Q+ +A+ R +++ +EV Q +L + L N+ ++E+ NK+L K
Sbjct: 189 KKNIAAERKEAKQEKEEAD-RYQRLKDEVVRAQVQLQLFK--LYHNEVEIEKLNKELASK 245
Query: 289 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN-RMCKVLENR 465
K++ + + + ++++ +++L K ++++ E ++ + K EN
Sbjct: 246 NKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENT 305
Query: 466 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
+ + ++++ L+ A+ + G DE+ +++ VE + E+R+ + +
Sbjct: 306 SHK-IKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERM---EEESQSQ 361
Query: 646 EEELKVVGNSLKSLEVSEEKANQR 717
+L + N +K +E+A++R
Sbjct: 362 GRDLTLEENQVKKYHRLKEEASKR 385
Score = 40.7 bits (91), Expect = 0.005
Identities = 37/203 (18%), Positives = 95/203 (46%), Gaps = 13/203 (6%)
Frame = +1
Query: 79 KKKMQAMKLEKDNA--MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 252
+K+ Q +K +++ + + K + ++ ++A +K ++ EL+K++ VE+ +
Sbjct: 293 QKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEE 352
Query: 253 KLEQAN----KDLEEKEKQL-------TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 399
++E+ + +DL +E Q+ A L +++++ D + ++R ++
Sbjct: 353 RMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEER 412
Query: 400 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 579
K +E + + R + + R ++ EE + L+E + L + + + R++
Sbjct: 413 KKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDE 472
Query: 580 VEDELEVAEDRVKSGDAKISELE 648
+ EL +++ GDA+I E
Sbjct: 473 INKELNQVMEQL--GDARIDRQE 493
Score = 40.7 bits (91), Expect = 0.005
Identities = 50/222 (22%), Positives = 96/222 (43%), Gaps = 7/222 (3%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-------VRELQKKLAQVEED 234
I+ + +L++D DK EQ + EK+ +E + E +L ++
Sbjct: 819 IQLDFEKNQLKEDQ--DKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQ 876
Query: 235 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 414
+ K+++ N ++EE K+L E+ L ++V IE LE ++RS + LL+A
Sbjct: 877 HLAKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLE--QKRSD--RHNLLQA 932
Query: 415 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 594
CK+ + + + MD ++ + E ED+ S +S + + L
Sbjct: 933 ----------CKMQDIKLPLSKGTMDDISQE--EGSSQGEDSVSGSQRISS--IYAREAL 978
Query: 595 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ D K ++ EEE+K N+L+ ++ QR+
Sbjct: 979 IEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRI 1020
Score = 37.5 bits (83), Expect = 0.048
Identities = 45/227 (19%), Positives = 98/227 (43%), Gaps = 11/227 (4%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQAR--DANLRAE-----KVNEEVRELQKKLAQV 225
MD ++ +++ K E M + E++ + D+ L + K E KKL
Sbjct: 256 MDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAA 315
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
++ L + ++ D++E EK++ + E + Q+ EE +E EE +
Sbjct: 316 KKSLQNAQKHYKKRKGDMDELEKEMLSVE-------KARQEFEERME--EESQSQGRDLT 366
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
LE Q + +R+ + RA + +++ K + + + K E K+
Sbjct: 367 LEENQ-VKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKL 425
Query: 586 DELEVAEDRVKSGDAKIS----ELEEELKVVGNSLKSLEVSEEKANQ 714
E+E + R++ + I+ LEE+ K+ G + +E+++ + ++
Sbjct: 426 REIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDE 472
Score = 32.7 bits (71), Expect = 1.4
Identities = 45/217 (20%), Positives = 89/217 (41%), Gaps = 21/217 (9%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL-------AQV 225
++ +KK+ Q D M + + Q N E+ E++KKL +
Sbjct: 849 IEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHL 908
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI--EEDLEKSEER-SGTAQ 396
++++ + KLEQ D + + ++ + I EE + E+ SG+ +
Sbjct: 909 QKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLSKGTMDDISQEEGSSQGEDSVSGSQR 968
Query: 397 QKLLEAQQSADE--NNRMCKVLENRAQQDE--ERMDQLTNQLKE-----ARLLAED--AD 543
+ A+++ E +C+ L++ ++E + M+ L +L E R+ A + A
Sbjct: 969 ISSIYAREALIEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRIAAPNMKAM 1028
Query: 544 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 654
K + V K DE E A R K ++++E
Sbjct: 1029 EKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKE 1065
>M97501-1|AAA35693.1| 1392|Homo sapiens cytoplasmic linker protein-170
alpha-2 protein.
Length = 1392
Score = 58.4 bits (135), Expect = 2e-08
Identities = 43/227 (18%), Positives = 102/227 (44%), Gaps = 8/227 (3%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
++A +K+++ +++EK+ KA + ++ + L+ + E + E+ + +E++L +
Sbjct: 751 LEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQIL 810
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
K K +A+++ ++ + T ++ + + DLEK E + K E +
Sbjct: 811 KEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDERE 870
Query: 427 DENNRMCKVLENR----AQQDEERMDQLTNQLKEARLLAEDADG---KSDEVSRKLAFVE 585
++ + + LEN + + QLT E RL D + K + + +F++
Sbjct: 871 EQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQ 930
Query: 586 DELEVAEDRVKSGDAKISEL-EEELKVVGNSLKSLEVSEEKANQRVE 723
+E + + + ++ EEE K + L LE E ++ + +
Sbjct: 931 KSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQ 977
Score = 50.4 bits (115), Expect = 6e-06
Identities = 68/239 (28%), Positives = 104/239 (43%), Gaps = 20/239 (8%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR--------EL 204
QQ+AA +KK KL + K +T Q ++ R E+ E + L
Sbjct: 944 QQEAAKKHEEEKKELERKLS--DLEKKMETSHNQCQELKARYERATSETKTKHEEILQNL 1001
Query: 205 QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS 384
QK L E+ L + + ++LEE KQ A +A+ A QI E + K E++
Sbjct: 1002 QKTLLDTEDKLKGAREENSGLLQELEELRKQ--AEKAKAAQTAEDAMQIMEQMTK--EKT 1057
Query: 385 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEE---RMDQLT--NQ-----LKEARLLAE 534
T Q +A N + + EN + EE + LT NQ KE L +
Sbjct: 1058 ETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQ 1117
Query: 535 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKIS--ELEEELKVVGNSLKSLEVSEEK 705
A KS ++S A E+ +++AE+ +S D S +LEEE V+ N L ++ E K
Sbjct: 1118 AAAQKSQQLS---ALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESK 1173
Score = 40.3 bits (90), Expect = 0.007
Identities = 41/203 (20%), Positives = 91/203 (44%), Gaps = 4/203 (1%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED----LILNKNKLEQANKD 276
K++ + +T +++ + EK+++E L+ KL ++ + L K+KLE A
Sbjct: 528 KEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIAS 587
Query: 277 LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 456
++ ++L + ++ L + + E L+ E+ Q +E Q+ ++ R
Sbjct: 588 HQQAMEELKVSFSK--GLGTETAEFAE-LKTQIEKMRLDYQHEIENLQNQQDSERAAHAK 644
Query: 457 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 636
E A + + M + + + D D+ ++ ++L+ AE +VK +
Sbjct: 645 EMEALR-AKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQ 703
Query: 637 SELEEELKVVGNSLKSLEVSEEK 705
++ E+ KV+ N L+ +EEK
Sbjct: 704 AKCNEQTKVIDNFTSQLKATEEK 726
Score = 37.5 bits (83), Expect = 0.048
Identities = 41/136 (30%), Positives = 65/136 (47%), Gaps = 14/136 (10%)
Frame = +1
Query: 292 KQLTATEAEVAALNRKVQQIEE-----DLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 456
++++ T A AL K Q IE+ DLE++E T+ +E + + + VL
Sbjct: 345 RKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVL 404
Query: 457 ENRAQQDE-----ERMD----QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 609
E A+ D+ E D +L NQL+E + ED + +E S + +LEVA
Sbjct: 405 ELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEES----ITKGDLEVATV 460
Query: 610 RVKSGDAKISELEEEL 657
KS +I ELE++L
Sbjct: 461 SEKS---RIMELEKDL 473
>D80000-1|BAA11495.2| 1233|Homo sapiens KIAA0178 protein.
Length = 1233
Score = 58.4 bits (135), Expect = 2e-08
Identities = 42/165 (25%), Positives = 89/165 (53%), Gaps = 6/165 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQ-QARDANLRAEKVNEEVR---ELQKKL 216
+++ MD ++K+M +++ + ++ + Q Q RD L +V + R E K+
Sbjct: 327 KKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRA 386
Query: 217 AQVEEDLI-LNKN-KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 390
A + ++L N++ K +Q DLEE++K TEA++ R++++ ++ +EK EE T
Sbjct: 387 ATLAQELEKFNRDQKADQDRLDLEERKK--VETEAKIKQKLREIEENQKRIEKLEEYITT 444
Query: 391 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 525
++Q L E ++ E ++ + R + + ++Q+ QL +AR+
Sbjct: 445 SKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARI 489
Score = 49.6 bits (113), Expect = 1e-05
Identities = 45/212 (21%), Positives = 98/212 (46%), Gaps = 18/212 (8%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL-------EQANKDLEEKEKQL 300
E + N N+E+ + +K++ +VE++L K +L +Q K+++EK+ +L
Sbjct: 232 EVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSEL 291
Query: 301 TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDE 480
+ + LE +++ AQ+ + + DE + +E Q+ E
Sbjct: 292 NQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFE 351
Query: 481 ERMDQ--------LT---NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 627
ERM++ LT NQ+K+ L E+A ++ ++++L + + +DR+ +
Sbjct: 352 ERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEE 411
Query: 628 AKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
K E E ++K L+ +E ++++ + E
Sbjct: 412 RKKVETEAKIK---QKLREIEENQKRIEKLEE 440
Score = 44.8 bits (101), Expect = 3e-04
Identities = 38/204 (18%), Positives = 98/204 (48%), Gaps = 1/204 (0%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
K N + +Q+ +A+ R +++ +EV Q +L + L N+ ++E+ NK+L K
Sbjct: 189 KKNIAAERKEAKQEKEEAD-RYQRLKDEVVRAQVQLQLFK--LYHNEVEIEKLNKELASK 245
Query: 289 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN-RMCKVLENR 465
K++ + + + ++++ +++L K ++++ E ++ + K EN
Sbjct: 246 NKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENT 305
Query: 466 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
+ + ++++ L+ A+ + G DE+ +++ VE + E+R+ + +
Sbjct: 306 SHK-IKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERM---EEESQSQ 361
Query: 646 EEELKVVGNSLKSLEVSEEKANQR 717
+L + N +K +E+A++R
Sbjct: 362 GRDLTLEENQVKKYHRLKEEASKR 385
Score = 40.7 bits (91), Expect = 0.005
Identities = 37/203 (18%), Positives = 95/203 (46%), Gaps = 13/203 (6%)
Frame = +1
Query: 79 KKKMQAMKLEKDNA--MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 252
+K+ Q +K +++ + + K + ++ ++A +K ++ EL+K++ VE+ +
Sbjct: 293 QKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEE 352
Query: 253 KLEQAN----KDLEEKEKQL-------TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 399
++E+ + +DL +E Q+ A L +++++ D + ++R ++
Sbjct: 353 RMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEER 412
Query: 400 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 579
K +E + + R + + R ++ EE + L+E + L + + + R++
Sbjct: 413 KKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDE 472
Query: 580 VEDELEVAEDRVKSGDAKISELE 648
+ EL +++ GDA+I E
Sbjct: 473 INKELNQVMEQL--GDARIDRQE 493
Score = 40.7 bits (91), Expect = 0.005
Identities = 50/222 (22%), Positives = 96/222 (43%), Gaps = 7/222 (3%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-------VRELQKKLAQVEED 234
I+ + +L++D DK EQ + EK+ +E + E +L ++
Sbjct: 819 IQLDFEKNQLKEDQ--DKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQ 876
Query: 235 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 414
+ K+++ N ++EE K+L E+ L ++V IE LE ++RS + LL+A
Sbjct: 877 HLAKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLE--QKRSD--RHNLLQA 932
Query: 415 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 594
CK+ + + + MD ++ + E ED+ S +S + + L
Sbjct: 933 ----------CKMQDIKLPLSKGTMDDISQE--EGSSQGEDSVSGSQRISS--IYAREAL 978
Query: 595 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ D K ++ EEE+K N+L+ ++ QR+
Sbjct: 979 IEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRI 1020
Score = 37.5 bits (83), Expect = 0.048
Identities = 45/227 (19%), Positives = 98/227 (43%), Gaps = 11/227 (4%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQAR--DANLRAE-----KVNEEVRELQKKLAQV 225
MD ++ +++ K E M + E++ + D+ L + K E KKL
Sbjct: 256 MDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAA 315
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
++ L + ++ D++E EK++ + E + Q+ EE +E EE +
Sbjct: 316 KKSLQNAQKHYKKRKGDMDELEKEMLSVE-------KARQEFEERME--EESQSQGRDLT 366
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
LE Q + +R+ + RA + +++ K + + + K E K+
Sbjct: 367 LEENQ-VKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKL 425
Query: 586 DELEVAEDRVKSGDAKIS----ELEEELKVVGNSLKSLEVSEEKANQ 714
E+E + R++ + I+ LEE+ K+ G + +E+++ + ++
Sbjct: 426 REIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDE 472
Score = 32.7 bits (71), Expect = 1.4
Identities = 45/217 (20%), Positives = 89/217 (41%), Gaps = 21/217 (9%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL-------AQV 225
++ +KK+ Q D M + + Q N E+ E++KKL +
Sbjct: 849 IEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHL 908
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI--EEDLEKSEER-SGTAQ 396
++++ + KLEQ D + + ++ + I EE + E+ SG+ +
Sbjct: 909 QKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLSKGTMDDISQEEGSSQGEDSVSGSQR 968
Query: 397 QKLLEAQQSADE--NNRMCKVLENRAQQDE--ERMDQLTNQLKE-----ARLLAED--AD 543
+ A+++ E +C+ L++ ++E + M+ L +L E R+ A + A
Sbjct: 969 ISSIYAREALIEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRIAAPNMKAM 1028
Query: 544 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 654
K + V K DE E A R K ++++E
Sbjct: 1029 EKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKE 1065
>BC126305-1|AAI26306.1| 1438|Homo sapiens CLIP1 protein protein.
Length = 1438
Score = 58.4 bits (135), Expect = 2e-08
Identities = 43/227 (18%), Positives = 102/227 (44%), Gaps = 8/227 (3%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
++A +K+++ +++EK+ KA + ++ + L+ + E + E+ + +E++L +
Sbjct: 797 LEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQIL 856
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
K K +A+++ ++ + T ++ + + DLEK E + K E +
Sbjct: 857 KEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDERE 916
Query: 427 DENNRMCKVLENR----AQQDEERMDQLTNQLKEARLLAEDADG---KSDEVSRKLAFVE 585
++ + + LEN + + QLT E RL D + K + + +F++
Sbjct: 917 EQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQ 976
Query: 586 DELEVAEDRVKSGDAKISEL-EEELKVVGNSLKSLEVSEEKANQRVE 723
+E + + + ++ EEE K + L LE E ++ + +
Sbjct: 977 KSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQ 1023
Score = 50.4 bits (115), Expect = 6e-06
Identities = 68/239 (28%), Positives = 104/239 (43%), Gaps = 20/239 (8%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR--------EL 204
QQ+AA +KK KL + K +T Q ++ R E+ E + L
Sbjct: 990 QQEAAKKHEEEKKELERKLS--DLEKKMETSHNQCQELKARYERATSETKTKHEEILQNL 1047
Query: 205 QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS 384
QK L E+ L + + ++LEE KQ A +A+ A QI E + K E++
Sbjct: 1048 QKTLLDTEDKLKGAREENSGLLQELEELRKQ--ADKAKAAQTAEDAMQIMEQMTK--EKT 1103
Query: 385 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEE---RMDQLT--NQ-----LKEARLLAE 534
T Q +A N + + EN + EE + LT NQ KE L +
Sbjct: 1104 ETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQ 1163
Query: 535 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKIS--ELEEELKVVGNSLKSLEVSEEK 705
A KS ++S A E+ +++AE+ +S D S +LEEE V+ N L ++ E K
Sbjct: 1164 AAAQKSQQLS---ALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESK 1219
Score = 43.2 bits (97), Expect = 0.001
Identities = 50/214 (23%), Positives = 92/214 (42%), Gaps = 4/214 (1%)
Frame = +1
Query: 28 FNSTGP*QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQ 207
F ST P + KA + + A L++ + + A + R + + E
Sbjct: 283 FPSTTPAKAKANAVRRVMATTSA-SLKRSPSASSLSSMSSVASSVSSRPSRTGL-LTETS 340
Query: 208 KKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 387
+ A+ + L++ + +E+ + AEVA V +IE++L + R G
Sbjct: 341 SRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALA--RDG 398
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
Q +LE + D+ M + D E+++ L NQL+E + ED + +E S
Sbjct: 399 H-DQHVLELEAKMDQLRTMVEAA------DREKVE-LLNQLEEEKRKVEDLQFRVEEESI 450
Query: 568 KLAFVEDELEVAED----RVKSGDAKISELEEEL 657
+E + +++ED + K A+I ELE+ L
Sbjct: 451 TKGDLEQKSQISEDPENTQTKLEHARIKELEQSL 484
Score = 40.3 bits (90), Expect = 0.007
Identities = 41/203 (20%), Positives = 91/203 (44%), Gaps = 4/203 (1%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED----LILNKNKLEQANKD 276
K++ + +T +++ + EK+++E L+ KL ++ + L K+KLE A
Sbjct: 574 KEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIAS 633
Query: 277 LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 456
++ ++L + ++ L + + E L+ E+ Q +E Q+ ++ R
Sbjct: 634 HQQAMEELKVSFSK--GLGTETAEFAE-LKTQIEKMRLDYQHEIENLQNQQDSERAAHAK 690
Query: 457 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 636
E A + + M + + + D D+ ++ ++L+ AE +VK +
Sbjct: 691 EMEALR-AKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQ 749
Query: 637 SELEEELKVVGNSLKSLEVSEEK 705
++ E+ KV+ N L+ +EEK
Sbjct: 750 AKCNEQTKVIDNFTSQLKATEEK 772
>BC114213-1|AAI14214.1| 1392|Homo sapiens CAP-GLY domain containing
linker protein 1 protein.
Length = 1392
Score = 58.4 bits (135), Expect = 2e-08
Identities = 43/227 (18%), Positives = 102/227 (44%), Gaps = 8/227 (3%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
++A +K+++ +++EK+ KA + ++ + L+ + E + E+ + +E++L +
Sbjct: 751 LEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQIL 810
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
K K +A+++ ++ + T ++ + + DLEK E + K E +
Sbjct: 811 KEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDERE 870
Query: 427 DENNRMCKVLENR----AQQDEERMDQLTNQLKEARLLAEDADG---KSDEVSRKLAFVE 585
++ + + LEN + + QLT E RL D + K + + +F++
Sbjct: 871 EQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQ 930
Query: 586 DELEVAEDRVKSGDAKISEL-EEELKVVGNSLKSLEVSEEKANQRVE 723
+E + + + ++ EEE K + L LE E ++ + +
Sbjct: 931 KSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQ 977
Score = 50.4 bits (115), Expect = 6e-06
Identities = 68/239 (28%), Positives = 104/239 (43%), Gaps = 20/239 (8%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR--------EL 204
QQ+AA +KK KL + K +T Q ++ R E+ E + L
Sbjct: 944 QQEAAKKHEEEKKELERKLS--DLEKKMETSHNQCQELKARYERATSETKTKHEEILQNL 1001
Query: 205 QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS 384
QK L E+ L + + ++LEE KQ A +A+ A QI E + K E++
Sbjct: 1002 QKTLLDTEDKLKGAREENSGLLQELEELRKQ--ADKAKAAQTAEDAMQIMEQMTK--EKT 1057
Query: 385 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEE---RMDQLT--NQ-----LKEARLLAE 534
T Q +A N + + EN + EE + LT NQ KE L +
Sbjct: 1058 ETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQ 1117
Query: 535 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKIS--ELEEELKVVGNSLKSLEVSEEK 705
A KS ++S A E+ +++AE+ +S D S +LEEE V+ N L ++ E K
Sbjct: 1118 AAAQKSQQLS---ALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESK 1173
Score = 37.5 bits (83), Expect = 0.048
Identities = 41/136 (30%), Positives = 65/136 (47%), Gaps = 14/136 (10%)
Frame = +1
Query: 292 KQLTATEAEVAALNRKVQQIEE-----DLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 456
++++ T A AL K Q IE+ DLE++E T+ +E + + + VL
Sbjct: 345 RKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVL 404
Query: 457 ENRAQQDE-----ERMD----QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 609
E A+ D+ E D +L NQL+E + ED + +E S + +LEVA
Sbjct: 405 ELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEES----ITKGDLEVATV 460
Query: 610 RVKSGDAKISELEEEL 657
KS +I ELE++L
Sbjct: 461 SEKS---RIMELEKDL 473
Score = 36.7 bits (81), Expect = 0.084
Identities = 40/203 (19%), Positives = 89/203 (43%), Gaps = 4/203 (1%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED----LILNKNKLEQANKD 276
K++ + +T +++ + EK+++E L+ KL ++ + L K+KLE A
Sbjct: 528 KEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIAS 587
Query: 277 LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 456
++ ++L + ++ L + + E L+ E+ Q +E Q+ + R
Sbjct: 588 HQQAMEELKVSFSK--GLGAETAEFAE-LKTQIEKMRLDYQHEIENLQNQQNSERAAHAK 644
Query: 457 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 636
E A + + M + + + D D+ ++ ++L+ AE +VK +
Sbjct: 645 EMEALR-AKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQ 703
Query: 637 SELEEELKVVGNSLKSLEVSEEK 705
++ E+ KV+ N + +EEK
Sbjct: 704 AKCNEQTKVIDNFTSQPKATEEK 726
>BC112127-1|AAI12128.1| 1233|Homo sapiens SMC1 structural
maintenance of chromosomes 1-like 1 protein.
Length = 1233
Score = 58.4 bits (135), Expect = 2e-08
Identities = 42/165 (25%), Positives = 89/165 (53%), Gaps = 6/165 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQ-QARDANLRAEKVNEEVR---ELQKKL 216
+++ MD ++K+M +++ + ++ + Q Q RD L +V + R E K+
Sbjct: 327 KKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRA 386
Query: 217 AQVEEDLI-LNKN-KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 390
A + ++L N++ K +Q DLEE++K TEA++ R++++ ++ +EK EE T
Sbjct: 387 ATLAQELEKFNRDQKADQDRLDLEERKK--VETEAKIKQKLREIEENQKRIEKLEEYITT 444
Query: 391 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 525
++Q L E ++ E ++ + R + + ++Q+ QL +AR+
Sbjct: 445 SKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARI 489
Score = 49.6 bits (113), Expect = 1e-05
Identities = 45/212 (21%), Positives = 98/212 (46%), Gaps = 18/212 (8%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL-------EQANKDLEEKEKQL 300
E + N N+E+ + +K++ +VE++L K +L +Q K+++EK+ +L
Sbjct: 232 EVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSEL 291
Query: 301 TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDE 480
+ + LE +++ AQ+ + + DE + +E Q+ E
Sbjct: 292 NQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFE 351
Query: 481 ERMDQ--------LT---NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 627
ERM++ LT NQ+K+ L E+A ++ ++++L + + +DR+ +
Sbjct: 352 ERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEE 411
Query: 628 AKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
K E E ++K L+ +E ++++ + E
Sbjct: 412 RKKVETEAKIK---QKLREIEENQKRIEKLEE 440
Score = 44.8 bits (101), Expect = 3e-04
Identities = 38/204 (18%), Positives = 98/204 (48%), Gaps = 1/204 (0%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
K N + +Q+ +A+ R +++ +EV Q +L + L N+ ++E+ NK+L K
Sbjct: 189 KKNIAAERKEAKQEKEEAD-RYQRLKDEVVRAQVQLQLFK--LYHNEVEIEKLNKELASK 245
Query: 289 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN-RMCKVLENR 465
K++ + + + ++++ +++L K ++++ E ++ + K EN
Sbjct: 246 NKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENT 305
Query: 466 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
+ + ++++ L+ A+ + G DE+ +++ VE + E+R+ + +
Sbjct: 306 SHK-IKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERM---EEESQSQ 361
Query: 646 EEELKVVGNSLKSLEVSEEKANQR 717
+L + N +K +E+A++R
Sbjct: 362 GRDLTLEENQVKKYHRLKEEASKR 385
Score = 40.7 bits (91), Expect = 0.005
Identities = 37/203 (18%), Positives = 95/203 (46%), Gaps = 13/203 (6%)
Frame = +1
Query: 79 KKKMQAMKLEKDNA--MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 252
+K+ Q +K +++ + + K + ++ ++A +K ++ EL+K++ VE+ +
Sbjct: 293 QKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEE 352
Query: 253 KLEQAN----KDLEEKEKQL-------TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 399
++E+ + +DL +E Q+ A L +++++ D + ++R ++
Sbjct: 353 RMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEER 412
Query: 400 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 579
K +E + + R + + R ++ EE + L+E + L + + + R++
Sbjct: 413 KKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDE 472
Query: 580 VEDELEVAEDRVKSGDAKISELE 648
+ EL +++ GDA+I E
Sbjct: 473 INKELNQVMEQL--GDARIDRQE 493
Score = 40.7 bits (91), Expect = 0.005
Identities = 50/222 (22%), Positives = 96/222 (43%), Gaps = 7/222 (3%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-------VRELQKKLAQVEED 234
I+ + +L++D DK EQ + EK+ +E + E +L ++
Sbjct: 819 IQLDFEKNQLKEDQ--DKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQ 876
Query: 235 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 414
+ K+++ N ++EE K+L E+ L ++V IE LE ++RS + LL+A
Sbjct: 877 HLAKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLE--QKRSD--RHNLLQA 932
Query: 415 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 594
CK+ + + + MD ++ + E ED+ S +S + + L
Sbjct: 933 ----------CKMQDIKLPLSKGTMDDISQE--EGSSQGEDSVSGSQRISS--IYAREAL 978
Query: 595 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ D K ++ EEE+K N+L+ ++ QR+
Sbjct: 979 IEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRI 1020
Score = 37.5 bits (83), Expect = 0.048
Identities = 45/227 (19%), Positives = 98/227 (43%), Gaps = 11/227 (4%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQAR--DANLRAE-----KVNEEVRELQKKLAQV 225
MD ++ +++ K E M + E++ + D+ L + K E KKL
Sbjct: 256 MDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAA 315
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
++ L + ++ D++E EK++ + E + Q+ EE +E EE +
Sbjct: 316 KKSLQNAQKHYKKRKGDMDELEKEMLSVE-------KARQEFEERME--EESQSQGRDLT 366
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
LE Q + +R+ + RA + +++ K + + + K E K+
Sbjct: 367 LEENQ-VKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKL 425
Query: 586 DELEVAEDRVKSGDAKIS----ELEEELKVVGNSLKSLEVSEEKANQ 714
E+E + R++ + I+ LEE+ K+ G + +E+++ + ++
Sbjct: 426 REIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDE 472
Score = 32.7 bits (71), Expect = 1.4
Identities = 45/217 (20%), Positives = 89/217 (41%), Gaps = 21/217 (9%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL-------AQV 225
++ +KK+ Q D M + + Q N E+ E++KKL +
Sbjct: 849 IEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHL 908
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI--EEDLEKSEER-SGTAQ 396
++++ + KLEQ D + + ++ + I EE + E+ SG+ +
Sbjct: 909 QKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLSKGTMDDISQEEGSSQGEDSVSGSQR 968
Query: 397 QKLLEAQQSADE--NNRMCKVLENRAQQDE--ERMDQLTNQLKE-----ARLLAED--AD 543
+ A+++ E +C+ L++ ++E + M+ L +L E R+ A + A
Sbjct: 969 ISSIYAREALIEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRIAAPNMKAM 1028
Query: 544 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 654
K + V K DE E A R K ++++E
Sbjct: 1029 EKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKE 1065
>BC064368-1|AAH64368.1| 847|Homo sapiens SMC1A protein protein.
Length = 847
Score = 58.4 bits (135), Expect = 2e-08
Identities = 42/165 (25%), Positives = 89/165 (53%), Gaps = 6/165 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQ-QARDANLRAEKVNEEVR---ELQKKL 216
+++ MD ++K+M +++ + ++ + Q Q RD L +V + R E K+
Sbjct: 327 KKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRA 386
Query: 217 AQVEEDLI-LNKN-KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 390
A + ++L N++ K +Q DLEE++K TEA++ R++++ ++ +EK EE T
Sbjct: 387 ATLAQELEKFNRDQKADQDRLDLEERKK--VETEAKIKQKLREIEENQKRIEKLEEYITT 444
Query: 391 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 525
++Q L E ++ E ++ + R + + ++Q+ QL +AR+
Sbjct: 445 SKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARI 489
Score = 49.6 bits (113), Expect = 1e-05
Identities = 45/212 (21%), Positives = 98/212 (46%), Gaps = 18/212 (8%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL-------EQANKDLEEKEKQL 300
E + N N+E+ + +K++ +VE++L K +L +Q K+++EK+ +L
Sbjct: 232 EVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSEL 291
Query: 301 TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDE 480
+ + LE +++ AQ+ + + DE + +E Q+ E
Sbjct: 292 NQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFE 351
Query: 481 ERMDQ--------LT---NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 627
ERM++ LT NQ+K+ L E+A ++ ++++L + + +DR+ +
Sbjct: 352 ERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEE 411
Query: 628 AKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
K E E ++K L+ +E ++++ + E
Sbjct: 412 RKKVETEAKIK---QKLREIEENQKRIEKLEE 440
Score = 44.8 bits (101), Expect = 3e-04
Identities = 38/204 (18%), Positives = 98/204 (48%), Gaps = 1/204 (0%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
K N + +Q+ +A+ R +++ +EV Q +L + L N+ ++E+ NK+L K
Sbjct: 189 KKNIAAERKEAKQEKEEAD-RYQRLKDEVVRAQVQLQLFK--LYHNEVEIEKLNKELASK 245
Query: 289 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN-RMCKVLENR 465
K++ + + + ++++ +++L K ++++ E ++ + K EN
Sbjct: 246 NKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENT 305
Query: 466 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
+ + ++++ L+ A+ + G DE+ +++ VE + E+R+ + +
Sbjct: 306 SHK-IKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERM---EEESQSQ 361
Query: 646 EEELKVVGNSLKSLEVSEEKANQR 717
+L + N +K +E+A++R
Sbjct: 362 GRDLTLEENQVKKYHRLKEEASKR 385
Score = 40.7 bits (91), Expect = 0.005
Identities = 37/203 (18%), Positives = 95/203 (46%), Gaps = 13/203 (6%)
Frame = +1
Query: 79 KKKMQAMKLEKDNA--MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 252
+K+ Q +K +++ + + K + ++ ++A +K ++ EL+K++ VE+ +
Sbjct: 293 QKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEE 352
Query: 253 KLEQAN----KDLEEKEKQL-------TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 399
++E+ + +DL +E Q+ A L +++++ D + ++R ++
Sbjct: 353 RMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEER 412
Query: 400 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 579
K +E + + R + + R ++ EE + L+E + L + + + R++
Sbjct: 413 KKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDE 472
Query: 580 VEDELEVAEDRVKSGDAKISELE 648
+ EL +++ GDA+I E
Sbjct: 473 INKELNQVMEQL--GDARIDRQE 493
Score = 37.5 bits (83), Expect = 0.048
Identities = 45/227 (19%), Positives = 98/227 (43%), Gaps = 11/227 (4%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQAR--DANLRAE-----KVNEEVRELQKKLAQV 225
MD ++ +++ K E M + E++ + D+ L + K E KKL
Sbjct: 256 MDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAA 315
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
++ L + ++ D++E EK++ + E + Q+ EE +E EE +
Sbjct: 316 KKSLQNAQKHYKKRKGDMDELEKEMLSVE-------KARQEFEERME--EESQSQGRDLT 366
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
LE Q + +R+ + RA + +++ K + + + K E K+
Sbjct: 367 LEENQ-VKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKL 425
Query: 586 DELEVAEDRVKSGDAKIS----ELEEELKVVGNSLKSLEVSEEKANQ 714
E+E + R++ + I+ LEE+ K+ G + +E+++ + ++
Sbjct: 426 REIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDE 472
>AL161779-1|CAI42089.1| 1233|Homo sapiens structural maintenance of
chromosomes 1A protein.
Length = 1233
Score = 58.4 bits (135), Expect = 2e-08
Identities = 42/165 (25%), Positives = 89/165 (53%), Gaps = 6/165 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQ-QARDANLRAEKVNEEVR---ELQKKL 216
+++ MD ++K+M +++ + ++ + Q Q RD L +V + R E K+
Sbjct: 327 KKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRA 386
Query: 217 AQVEEDLI-LNKN-KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 390
A + ++L N++ K +Q DLEE++K TEA++ R++++ ++ +EK EE T
Sbjct: 387 ATLAQELEKFNRDQKADQDRLDLEERKK--VETEAKIKQKLREIEENQKRIEKLEEYITT 444
Query: 391 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 525
++Q L E ++ E ++ + R + + ++Q+ QL +AR+
Sbjct: 445 SKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARI 489
Score = 49.6 bits (113), Expect = 1e-05
Identities = 45/212 (21%), Positives = 98/212 (46%), Gaps = 18/212 (8%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL-------EQANKDLEEKEKQL 300
E + N N+E+ + +K++ +VE++L K +L +Q K+++EK+ +L
Sbjct: 232 EVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSEL 291
Query: 301 TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDE 480
+ + LE +++ AQ+ + + DE + +E Q+ E
Sbjct: 292 NQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFE 351
Query: 481 ERMDQ--------LT---NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 627
ERM++ LT NQ+K+ L E+A ++ ++++L + + +DR+ +
Sbjct: 352 ERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEE 411
Query: 628 AKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
K E E ++K L+ +E ++++ + E
Sbjct: 412 RKKVETEAKIK---QKLREIEENQKRIEKLEE 440
Score = 44.8 bits (101), Expect = 3e-04
Identities = 38/204 (18%), Positives = 98/204 (48%), Gaps = 1/204 (0%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
K N + +Q+ +A+ R +++ +EV Q +L + L N+ ++E+ NK+L K
Sbjct: 189 KKNIAAERKEAKQEKEEAD-RYQRLKDEVVRAQVQLQLFK--LYHNEVEIEKLNKELASK 245
Query: 289 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN-RMCKVLENR 465
K++ + + + ++++ +++L K ++++ E ++ + K EN
Sbjct: 246 NKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENT 305
Query: 466 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
+ + ++++ L+ A+ + G DE+ +++ VE + E+R+ + +
Sbjct: 306 SHK-IKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERM---EEESQSQ 361
Query: 646 EEELKVVGNSLKSLEVSEEKANQR 717
+L + N +K +E+A++R
Sbjct: 362 GRDLTLEENQVKKYHRLKEEASKR 385
Score = 40.7 bits (91), Expect = 0.005
Identities = 37/203 (18%), Positives = 95/203 (46%), Gaps = 13/203 (6%)
Frame = +1
Query: 79 KKKMQAMKLEKDNA--MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 252
+K+ Q +K +++ + + K + ++ ++A +K ++ EL+K++ VE+ +
Sbjct: 293 QKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEE 352
Query: 253 KLEQAN----KDLEEKEKQL-------TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 399
++E+ + +DL +E Q+ A L +++++ D + ++R ++
Sbjct: 353 RMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEER 412
Query: 400 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 579
K +E + + R + + R ++ EE + L+E + L + + + R++
Sbjct: 413 KKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDE 472
Query: 580 VEDELEVAEDRVKSGDAKISELE 648
+ EL +++ GDA+I E
Sbjct: 473 INKELNQVMEQL--GDARIDRQE 493
Score = 40.7 bits (91), Expect = 0.005
Identities = 50/222 (22%), Positives = 96/222 (43%), Gaps = 7/222 (3%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-------VRELQKKLAQVEED 234
I+ + +L++D DK EQ + EK+ +E + E +L ++
Sbjct: 819 IQLDFEKNQLKEDQ--DKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQ 876
Query: 235 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 414
+ K+++ N ++EE K+L E+ L ++V IE LE ++RS + LL+A
Sbjct: 877 HLAKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLE--QKRSD--RHNLLQA 932
Query: 415 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 594
CK+ + + + MD ++ + E ED+ S +S + + L
Sbjct: 933 ----------CKMQDIKLPLSKGTMDDISQE--EGSSQGEDSVSGSQRISS--IYAREAL 978
Query: 595 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ D K ++ EEE+K N+L+ ++ QR+
Sbjct: 979 IEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRI 1020
Score = 37.5 bits (83), Expect = 0.048
Identities = 45/227 (19%), Positives = 98/227 (43%), Gaps = 11/227 (4%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQAR--DANLRAE-----KVNEEVRELQKKLAQV 225
MD ++ +++ K E M + E++ + D+ L + K E KKL
Sbjct: 256 MDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAA 315
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
++ L + ++ D++E EK++ + E + Q+ EE +E EE +
Sbjct: 316 KKSLQNAQKHYKKRKGDMDELEKEMLSVE-------KARQEFEERME--EESQSQGRDLT 366
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
LE Q + +R+ + RA + +++ K + + + K E K+
Sbjct: 367 LEENQ-VKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKL 425
Query: 586 DELEVAEDRVKSGDAKIS----ELEEELKVVGNSLKSLEVSEEKANQ 714
E+E + R++ + I+ LEE+ K+ G + +E+++ + ++
Sbjct: 426 REIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDE 472
Score = 32.7 bits (71), Expect = 1.4
Identities = 45/217 (20%), Positives = 89/217 (41%), Gaps = 21/217 (9%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL-------AQV 225
++ +KK+ Q D M + + Q N E+ E++KKL +
Sbjct: 849 IEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHL 908
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI--EEDLEKSEER-SGTAQ 396
++++ + KLEQ D + + ++ + I EE + E+ SG+ +
Sbjct: 909 QKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLSKGTMDDISQEEGSSQGEDSVSGSQR 968
Query: 397 QKLLEAQQSADE--NNRMCKVLENRAQQDE--ERMDQLTNQLKE-----ARLLAED--AD 543
+ A+++ E +C+ L++ ++E + M+ L +L E R+ A + A
Sbjct: 969 ISSIYAREALIEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRIAAPNMKAM 1028
Query: 544 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 654
K + V K DE E A R K ++++E
Sbjct: 1029 EKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKE 1065
>BC117209-1|AAI17210.1| 1438|Homo sapiens CLIP1 protein protein.
Length = 1438
Score = 58.0 bits (134), Expect = 3e-08
Identities = 43/227 (18%), Positives = 102/227 (44%), Gaps = 8/227 (3%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
++A +K+++ +++EK+ KA + ++ + L+ + E + E+ + +E++L +
Sbjct: 797 LEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQIL 856
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
K K +A+++ ++ + T ++ + + DLEK E + K E +
Sbjct: 857 KEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDERE 916
Query: 427 DENNRMCKVLENR----AQQDEERMDQLTNQLKEARLLAEDADG---KSDEVSRKLAFVE 585
++ + + LEN + + QLT E RL D + K + + +F++
Sbjct: 917 EQLIKAKEKLENDIAEIMKMSGDNPSQLTKMNDELRLKERDVEELQLKLTKANENASFLQ 976
Query: 586 DELEVAEDRVKSGDAKISEL-EEELKVVGNSLKSLEVSEEKANQRVE 723
+E + + + ++ EEE K + L LE E ++ + +
Sbjct: 977 KSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQ 1023
Score = 50.4 bits (115), Expect = 6e-06
Identities = 68/239 (28%), Positives = 104/239 (43%), Gaps = 20/239 (8%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR--------EL 204
QQ+AA +KK KL + K +T Q ++ R E+ E + L
Sbjct: 990 QQEAAKKHEEEKKELERKLS--DLEKKMETSHNQCQELKARYERATSETKTKHEEILQNL 1047
Query: 205 QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS 384
QK L E+ L + + ++LEE KQ A +A+ A QI E + K E++
Sbjct: 1048 QKTLLDTEDKLKGAREENSGLLQELEELRKQ--AEKAKAAQTAEDAMQIMEQMTK--EKT 1103
Query: 385 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEE---RMDQLT--NQ-----LKEARLLAE 534
T Q +A N + + EN + EE + LT NQ KE L +
Sbjct: 1104 ETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQ 1163
Query: 535 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKIS--ELEEELKVVGNSLKSLEVSEEK 705
A KS ++S A E+ +++AE+ +S D S +LEEE V+ N L ++ E K
Sbjct: 1164 AAAQKSQQLS---ALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESK 1219
Score = 43.2 bits (97), Expect = 0.001
Identities = 50/214 (23%), Positives = 92/214 (42%), Gaps = 4/214 (1%)
Frame = +1
Query: 28 FNSTGP*QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQ 207
F ST P + KA + + A L++ + + A + R + + E
Sbjct: 283 FPSTTPAKAKANAVRRVMATTSA-SLKRSPSASSLSSMSSVASSVSSRPSRTGL-LTETS 340
Query: 208 KKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 387
+ A+ + L++ + +E+ + AEVA V +IE++L + R G
Sbjct: 341 SRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALA--RDG 398
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
Q +LE + D+ M + D E+++ L NQL+E + ED + +E S
Sbjct: 399 H-DQHVLELEAKMDQLRTMVEAA------DREKVE-LLNQLEEEKRKVEDLQFRVEEESI 450
Query: 568 KLAFVEDELEVAED----RVKSGDAKISELEEEL 657
+E + +++ED + K A+I ELE+ L
Sbjct: 451 TKGDLEQKSQISEDPENTQTKLEHARIKELEQSL 484
Score = 40.3 bits (90), Expect = 0.007
Identities = 41/203 (20%), Positives = 91/203 (44%), Gaps = 4/203 (1%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED----LILNKNKLEQANKD 276
K++ + +T +++ + EK+++E L+ KL ++ + L K+KLE A
Sbjct: 574 KEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIAS 633
Query: 277 LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 456
++ ++L + ++ L + + E L+ E+ Q +E Q+ ++ R
Sbjct: 634 HQQAMEELKVSFSK--GLGTETAEFAE-LKTQIEKMRLDYQHEIENLQNQQDSERAAHAK 690
Query: 457 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 636
E A + + M + + + D D+ ++ ++L+ AE +VK +
Sbjct: 691 EMEALR-AKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQ 749
Query: 637 SELEEELKVVGNSLKSLEVSEEK 705
++ E+ KV+ N L+ +EEK
Sbjct: 750 AKCNEQTKVIDNFTSQLKATEEK 772
>X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein.
Length = 1411
Score = 57.6 bits (133), Expect = 4e-08
Identities = 51/215 (23%), Positives = 107/215 (49%), Gaps = 13/215 (6%)
Frame = +1
Query: 112 DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK---LEQANKDLE 282
D A + +Q+ + ++V ++++ Q+ +Q+E L K K LEQ ++LE
Sbjct: 670 DTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELE 729
Query: 283 EKEKQLTATEAEV-AALNRKVQQIEED--LEKSEERSGTAQQKLLEAQQSADENNRMCKV 453
+ K+L A EV A+ + +Q +++ L E T K LE ++ + R+
Sbjct: 730 GQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLD-- 787
Query: 454 LENRAQQDEERMDQLTNQLKEARLLAEDADGKS-------DEVSRKLAFVEDELEVAEDR 612
L+ +++ E +LT Q +E ++L +D + S +E++ ++ EL+ +
Sbjct: 788 LQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKME 847
Query: 613 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
++ ++S ++++L V +SLK+ + EK NQ+
Sbjct: 848 KEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQK 882
Score = 51.6 bits (118), Expect = 3e-06
Identities = 40/209 (19%), Positives = 99/209 (47%), Gaps = 7/209 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
Q K ++ I ++ + + + + E ++ + + ++ EL+ ++ ++E
Sbjct: 677 QDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLE 736
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE-------DLEKSEERSG 387
D + K EQA +DL+++ + T E L+++++ +E DL+K E
Sbjct: 737 ADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALE 796
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
+ +QKL + + +E + + E +Q+ + + ++L N+++ + + + +
Sbjct: 797 SIKQKLTKQE---EEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMT 853
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEE 654
+L+ V+D+L D +K+ SE E+E
Sbjct: 854 ELSTVKDKLSKVSDSLKNSK---SEFEKE 879
Score = 51.6 bits (118), Expect = 3e-06
Identities = 50/231 (21%), Positives = 110/231 (47%), Gaps = 12/231 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR----ELQKKL 216
Q+K+ +++IK+K+ + EK +T Q+ + ++ E++N ++ ELQK
Sbjct: 789 QKKSEALESIKQKLTKQEEEKQILKQDFETLSQETK---IQHEELNNRIQTTVTELQKVK 845
Query: 217 AQVE---EDLILNKNKLEQANKDLE----EKEKQLTATEAEVAALNRKVQQIEEDLEKSE 375
+ E +L K+KL + + L+ E EK+ +A + L + ++++ L+
Sbjct: 846 MEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQM 905
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
E + Q++L ++ + E + K+ N Q E++ Q N LK+ + G +
Sbjct: 906 ENTLKEQKELKKSLEKEKEASHQLKLELNSMQ---EQLIQAQNTLKQNEKEEQQLQGNIN 962
Query: 556 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL-KVVGNSLKSLEVSEEK 705
E+ + + ++E + +K + +ELE +L + + + + L +EK
Sbjct: 963 ELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEK 1013
Score = 51.2 bits (117), Expect = 4e-06
Identities = 35/184 (19%), Positives = 79/184 (42%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
K ++ K E + + + E +LQ++L Q ++L K K+ + E+
Sbjct: 965 KQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKS 1024
Query: 289 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRA 468
++ +++ ++ +DL+ EE+ AQ+ L+ + N++ + L+
Sbjct: 1025 QETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAK 1084
Query: 469 QQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE 648
E+ + QL+E +D + ++L + +L E+ + +I++L
Sbjct: 1085 ATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLN 1144
Query: 649 EELK 660
EELK
Sbjct: 1145 EELK 1148
Score = 50.0 bits (114), Expect = 8e-06
Identities = 49/210 (23%), Positives = 102/210 (48%), Gaps = 12/210 (5%)
Frame = +1
Query: 55 KAATMD---AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQV 225
KAA +D K+ ++++ +N + + ++ + ++ E+ +Q++L Q
Sbjct: 884 KAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQA 943
Query: 226 EEDLILNKNKLEQANKDL-------EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS 384
+ L N+ + +Q ++ E+K+KQ+ A + E+ K+ L+K+E +
Sbjct: 944 QNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGEL-----KIAV----LQKTELEN 994
Query: 385 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL--KEARLLAEDADGKSDE 558
QQ AQ+ A E ++ VL+N ++ +E QL + +E+ LLA D KS
Sbjct: 995 KLQQQLTQAAQELAAEKEKI-SVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKS-- 1051
Query: 559 VSRKLAFVEDELEVAEDRVKSGDAKISELE 648
V KL+ +++L +++ + + I EL+
Sbjct: 1052 VEEKLSLAQEDLISNRNQIGNQNKLIQELK 1081
Score = 47.2 bits (107), Expect = 6e-05
Identities = 50/214 (23%), Positives = 93/214 (43%), Gaps = 2/214 (0%)
Frame = +1
Query: 88 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL-ILNKNKLEQ 264
MQ ++ N + + + EQQ + N+ K + E ++ Q + Q E + +L K +LE
Sbjct: 936 MQEQLIQAQNTLKQNEKEEQQLQ-GNINELKQSSEQKKKQIEALQGELKIAVLQKTELE- 993
Query: 265 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 444
NK ++QLT E+AA K+ ++ + EKS+E Q + +
Sbjct: 994 -NK----LQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQD 1048
Query: 445 CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS- 621
K +E + +E + NQ+ L ++ + + A E +L ++R K+
Sbjct: 1049 LKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQL---QERCKAL 1105
Query: 622 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
D + + +E ++V K E+ E K Q E
Sbjct: 1106 QDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKE 1139
Score = 44.4 bits (100), Expect = 4e-04
Identities = 52/243 (21%), Positives = 113/243 (46%), Gaps = 28/243 (11%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKV---NEEVRELQKKLA 219
+Q + + ++ + LE + + +A ++ R L +EK+ ++V +LQ KL+
Sbjct: 406 EQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQ--LSSEKLMDKEQQVADLQLKLS 463
Query: 220 QVEEDL---ILNKNKLE-QANKDLEEKEKQLTATEAEVAAL-----------------NR 336
++EE L + N +L+ Q +K ++ ++Q ++ A L ++
Sbjct: 464 RLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQ 523
Query: 337 KVQQIEEDLEKSEERSGTAQQK---LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQ 507
K+Q +E L+KS+E +++ L Q+ + + L+ + +E++ QLT +
Sbjct: 524 KIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEK 583
Query: 508 LK-EARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 684
LK ++ + + D+V + A L A+DRV S + ++EL +L +
Sbjct: 584 LKNQSESHKQAQENLHDQVQEQKA----HLRAAQDRVLSLETSVNELNSQLNESKEKVSQ 639
Query: 685 LEV 693
L++
Sbjct: 640 LDI 642
Score = 43.6 bits (98), Expect = 7e-04
Identities = 37/166 (22%), Positives = 73/166 (43%), Gaps = 1/166 (0%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAMDKADTC-EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
K+ + KLE D EQ+ R+ + ++V +E EL+K+ + E L
Sbjct: 1165 KQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKL------ 1218
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
+ +++EKE + E A L ++ + E+L ++ ++Q+++ E ++ D+
Sbjct: 1219 ----HSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDL 1274
Query: 436 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 573
VLE Q +++ L + + E K E+ RKL
Sbjct: 1275 RGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKL 1320
Score = 42.3 bits (95), Expect = 0.002
Identities = 35/191 (18%), Positives = 85/191 (44%), Gaps = 7/191 (3%)
Frame = +1
Query: 172 AEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI 351
+EK+ +E ++LQ + A E + +++L + +++ ++L ++ V L +K Q +
Sbjct: 248 SEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTL 307
Query: 352 -------EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL 510
E+D K EE+ Q + + + C+ L++R E + ++ +L
Sbjct: 308 TENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVEL 367
Query: 511 KEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
E + + EV K ++ E + + + + + +L+ E+ + + L E
Sbjct: 368 SEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETE 427
Query: 691 VSEEKANQRVE 723
+A+ R++
Sbjct: 428 RQLGEAHGRLK 438
Score = 42.3 bits (95), Expect = 0.002
Identities = 34/189 (17%), Positives = 81/189 (42%), Gaps = 4/189 (2%)
Frame = +1
Query: 148 QARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAA 327
Q D + +++ Q++L ++ L KL+ + + E L + + +
Sbjct: 661 QRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLS 720
Query: 328 LNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQ 507
L +K +++E ++K E S + +A Q + ++ LE RA + ++++
Sbjct: 721 LEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEI 780
Query: 508 LKEARLLAEDADGKSDEVSRKLAFVEDELEVAED--RVKSGDAKI--SELEEELKVVGNS 675
+ RL + + + +KL E+E ++ + S + KI EL ++
Sbjct: 781 VSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTE 840
Query: 676 LKSLEVSEE 702
L+ +++ +E
Sbjct: 841 LQKVKMEKE 849
>Z29064-1|CAA82305.1| 896|Homo sapiens AF-1p protein.
Length = 896
Score = 57.2 bits (132), Expect = 6e-08
Identities = 35/173 (20%), Positives = 88/173 (50%)
Frame = +1
Query: 175 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 354
+ +N E+ +LQ++ VE+DL ++ ++Q ++++ + ++ + L + QQ++
Sbjct: 336 DTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQ 395
Query: 355 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 534
E L++ +E+ +++L E ++ E ++ L+ E ++ +L +AR
Sbjct: 396 ELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAR---- 451
Query: 535 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 693
+E+SR ++ E E+ V+SG A++ L++ L+ + S+++
Sbjct: 452 ------EELSR----LQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQM 494
Score = 44.8 bits (101), Expect = 3e-04
Identities = 39/157 (24%), Positives = 74/157 (47%), Gaps = 14/157 (8%)
Frame = +1
Query: 292 KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 471
K+L E+ L R+ +E+DL++ E+ ++ + Q N + L+ + Q
Sbjct: 333 KELDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQ 392
Query: 472 QDEERMD-------QLTNQLKEARL-LAEDADG----KSDEVSRK--LAFVEDELEVAED 609
Q +E +D QL QLKE R AE+A K++ S++ ++ E+EL A +
Sbjct: 393 QVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKARE 452
Query: 610 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ + +ELEE ++ L+ L+ + + Q +
Sbjct: 453 ELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEI 489
>Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein.
Length = 2663
Score = 57.2 bits (132), Expect = 6e-08
Identities = 49/220 (22%), Positives = 109/220 (49%), Gaps = 9/220 (4%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
M + K++Q E + + D ++ ++++ E ++E+ K + EE+L +
Sbjct: 1423 MLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVA 1482
Query: 247 ----KNKLEQANK---DLEEKEKQLTATEAEVAALNRKVQ-QIEEDLEKSEERSGTAQQK 402
K + E N+ +L EKE +++ + ++ A+N K+Q +I+E EK E+ + +
Sbjct: 1483 HCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQLNIKQISE 1542
Query: 403 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 582
+ E + K ++ Q E +M +LTN+L+E++ + + +E+ R V
Sbjct: 1543 VQENVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKR----V 1598
Query: 583 EDELEVAEDRVKSGDAKI-SELEEELKVVGNSLKSLEVSE 699
++ L++ D++K +I ++++E + LK V+E
Sbjct: 1599 QEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNE 1638
Score = 45.6 bits (103), Expect = 2e-04
Identities = 42/178 (23%), Positives = 86/178 (48%), Gaps = 12/178 (6%)
Frame = +1
Query: 214 LAQVEEDLILNKNKLEQANKDLE----EKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 381
LA++E + + K +++ ++++ E++ T EA ++ + I E L K +E
Sbjct: 1323 LARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQE- 1381
Query: 382 SGTAQQKLLEAQQSADENNRMCKVLENRAQQD------EERMDQLTNQLKEARLLAEDAD 543
S + Q++ L ++ +E ++ +E +D E M L+ +L+E+ +
Sbjct: 1382 SQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVA 1441
Query: 544 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE--VSEEKAN 711
+ D++ R ++ E + ++ +K AK E EEELKV LK E ++E + N
Sbjct: 1442 KEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVN 1499
Score = 43.2 bits (97), Expect = 0.001
Identities = 41/203 (20%), Positives = 96/203 (47%), Gaps = 10/203 (4%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
+Q E++ +++E + + +E+L L ++L++ + + +++ E E+
Sbjct: 1056 QQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGEL 1115
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLE---NRAQQDEERMD 492
+ ++ ++EE L++ ++ QQ+LL Q+ E + +E N + E ++
Sbjct: 1116 SRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLE 1175
Query: 493 QL-TNQLKEARLLAED-ADGKSDEVSRK-LAFVEDELEVAEDRVKSGDAKIS----ELEE 651
+ T +L+ A+ L E+ + KS RK L ++ E D ++ +I + +E
Sbjct: 1176 HMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKE 1235
Query: 652 ELKVVGNSLKSLEVSEEKANQRV 720
ELK+ LK + + ++ + V
Sbjct: 1236 ELKIAHIHLKEHQETIDELRRSV 1258
Score = 41.9 bits (94), Expect = 0.002
Identities = 39/184 (21%), Positives = 87/184 (47%), Gaps = 9/184 (4%)
Frame = +1
Query: 124 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK---LEQANKDLEEKEK 294
+K QQ ++ + V EE+ E+QKK+ ++E KNK LE + E +
Sbjct: 1127 EKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQ 1186
Query: 295 QLTATEAEVAALNRKVQQIEEDLEKS-EERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 471
+L EV ++ K +++ ++L+KS E + + E + + + K+ +
Sbjct: 1187 KLNENYEEVKSIT-KERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLK 1245
Query: 472 QDEERMDQLTNQLKE--ARLL-AEDADGKSDEVSRKLAFVEDELEVAED--RVKSGDAKI 636
+ +E +D+L + E A+++ +D + ++ ++ + +E E+ + +V +
Sbjct: 1246 EHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKKVSETQETM 1305
Query: 637 SELE 648
+ELE
Sbjct: 1306 NELE 1309
Score = 41.5 bits (93), Expect = 0.003
Identities = 44/220 (20%), Positives = 102/220 (46%), Gaps = 2/220 (0%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 249
D +++ + +KLE+D K E +ARD ++ E + R L K+ + + L +
Sbjct: 1892 DNLRRVEETLKLERDQL--KESLQETKARDLEIQQEL--KTARMLSKEHKETVDKL---R 1944
Query: 250 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ--S 423
K+ + + + +K L ++ E+ +++Q+ E L + +E + +K+ E +Q
Sbjct: 1945 EKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKK 2004
Query: 424 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 603
E N +CK + Q + +L L+E R++A++ D + + L D+
Sbjct: 2005 QFEPNYLCKCEMDNFQLTK----KLHESLEEIRIVAKERD-ELRRIKESLKMERDQFIAT 2059
Query: 604 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ + D + +++ E +++ + + L S + R++
Sbjct: 2060 LREMIARDRQNHQVKPEKRLLSDGQQHLMESLREKCSRIK 2099
Score = 39.9 bits (89), Expect = 0.009
Identities = 53/236 (22%), Positives = 106/236 (44%), Gaps = 21/236 (8%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLR----AEKVNEEVRELQKKL 216
Q+K ++ +K++ + KL +N ++ + Q NL K +++R +++ L
Sbjct: 1640 QEKMCEIEHLKEQFETQKLNLEN-IETENIRLTQILHENLEEMRSVTKERDDLRSVEETL 1698
Query: 217 AQVEEDLILNKNKLEQANKDLEE-----------KEKQLTATEAE--VAALNRKVQQIEE 357
+VE D L +N E +DLE+ KE Q T + V+ ++ +++
Sbjct: 1699 -KVERDQ-LKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQK 1756
Query: 358 DLEKSEERSGTAQQKLLEAQQSADEN-NRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 534
DLE S + K+ E + A + + ++ E+ D+L+N K+ E
Sbjct: 1757 DLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDL----E 1812
Query: 535 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE---ELKVVGNSLKSLEV 693
+++ K E ++L E +L + V K+SE+E+ ++K +L LE+
Sbjct: 1813 NSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEI 1868
Score = 38.3 bits (85), Expect = 0.028
Identities = 32/156 (20%), Positives = 73/156 (46%)
Frame = +1
Query: 175 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 354
E++N+E+ L K+ + + L K +L ++L+EK +++ E+ L +++ +
Sbjct: 841 ERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRD 900
Query: 355 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 534
L+ E +KL QQ+ +E + + ++ +Q +E + +QLK
Sbjct: 901 SPLQTVEREKTLITEKL---QQTLEEVKTLTQEKDD-LKQLQESLQIERDQLKSD---IH 953
Query: 535 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE 642
D + + +L + L+ ++ + + +KISE
Sbjct: 954 DTVNMNIDTQEQLRNALESLKQHQETINTLKSKISE 989
Score = 34.7 bits (76), Expect = 0.34
Identities = 37/174 (21%), Positives = 76/174 (43%), Gaps = 2/174 (1%)
Frame = +1
Query: 175 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 354
EK+ +++ ++ QV N + N+ E +E+ T ++ + ++ ++
Sbjct: 2245 EKLKNGIQKENDRICQVNN--FFNNRIIAIMNESTEFEERSATISKE----WEQDLKSLK 2298
Query: 355 EDLEKSEERSGTAQQKLLEAQQ--SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 528
E EK + T + L Q ++N+ V Q E++ +L N L EA+
Sbjct: 2299 EKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEAK-- 2356
Query: 529 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
E A K ++ + ++ ELEV D + AK+ E + L+ +++ L+
Sbjct: 2357 -ESAMHKESKIIK----MQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQ 2405
Score = 31.5 bits (68), Expect = 3.2
Identities = 34/179 (18%), Positives = 82/179 (45%), Gaps = 6/179 (3%)
Frame = +1
Query: 79 KKKMQAMKLEKD--NAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE-DLILNK 249
+K +Q ++KD + D+ Q+ + L+ +V E+V KK+ ++E+
Sbjct: 1949 EKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEP 2008
Query: 250 NKLEQANKDLEEKEKQL--TATEAEVAALNR-KVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
N L + D + K+L + E + A R ++++I+E L+ ++ ++++ +
Sbjct: 2009 NYLCKCEMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIARDR 2068
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 597
+ ++L + Q E + + +++KE + D + ++R +E E+E
Sbjct: 2069 QNHQVKPEKRLLSDGQQHLMESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIE 2127
>U07707-1|AAA52101.1| 896|Homo sapiens epidermal growth factor
receptor substrate protein.
Length = 896
Score = 57.2 bits (132), Expect = 6e-08
Identities = 35/173 (20%), Positives = 88/173 (50%)
Frame = +1
Query: 175 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 354
+ +N E+ +LQ++ VE+DL ++ ++Q ++++ + ++ + L + QQ++
Sbjct: 336 DTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQ 395
Query: 355 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 534
E L++ +E+ +++L E ++ E ++ L+ E ++ +L +AR
Sbjct: 396 ELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAR---- 451
Query: 535 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 693
+E+SR ++ E E+ V+SG A++ L++ L+ + S+++
Sbjct: 452 ------EELSR----LQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQM 494
Score = 44.8 bits (101), Expect = 3e-04
Identities = 39/157 (24%), Positives = 74/157 (47%), Gaps = 14/157 (8%)
Frame = +1
Query: 292 KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 471
K+L E+ L R+ +E+DL++ E+ ++ + Q N + L+ + Q
Sbjct: 333 KELDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQ 392
Query: 472 QDEERMD-------QLTNQLKEARL-LAEDADG----KSDEVSRK--LAFVEDELEVAED 609
Q +E +D QL QLKE R AE+A K++ S++ ++ E+EL A +
Sbjct: 393 QVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKARE 452
Query: 610 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ + +ELEE ++ L+ L+ + + Q +
Sbjct: 453 ELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEI 489
>DQ367924-1|ABD34786.1| 896|Homo sapiens epidermal growth factor
receptor pathway substrate 15 protein.
Length = 896
Score = 57.2 bits (132), Expect = 6e-08
Identities = 35/173 (20%), Positives = 88/173 (50%)
Frame = +1
Query: 175 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 354
+ +N E+ +LQ++ VE+DL ++ ++Q ++++ + ++ + L + QQ++
Sbjct: 336 DTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQ 395
Query: 355 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 534
E L++ +E+ +++L E ++ E ++ L+ E ++ +L +AR
Sbjct: 396 ELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAR---- 451
Query: 535 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 693
+E+SR ++ E E+ V+SG A++ L++ L+ + S+++
Sbjct: 452 ------EELSR----LQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQM 494
Score = 44.8 bits (101), Expect = 3e-04
Identities = 39/157 (24%), Positives = 74/157 (47%), Gaps = 14/157 (8%)
Frame = +1
Query: 292 KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 471
K+L E+ L R+ +E+DL++ E+ ++ + Q N + L+ + Q
Sbjct: 333 KELDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQ 392
Query: 472 QDEERMD-------QLTNQLKEARL-LAEDADG----KSDEVSRK--LAFVEDELEVAED 609
Q +E +D QL QLKE R AE+A K++ S++ ++ E+EL A +
Sbjct: 393 QVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKARE 452
Query: 610 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ + +ELEE ++ L+ L+ + + Q +
Sbjct: 453 ELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEI 489
>AL671986-11|CAI13030.1| 896|Homo sapiens epidermal growth factor
receptor pathway substrate 15 protein.
Length = 896
Score = 57.2 bits (132), Expect = 6e-08
Identities = 35/173 (20%), Positives = 88/173 (50%)
Frame = +1
Query: 175 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 354
+ +N E+ +LQ++ VE+DL ++ ++Q ++++ + ++ + L + QQ++
Sbjct: 336 DTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQ 395
Query: 355 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 534
E L++ +E+ +++L E ++ E ++ L+ E ++ +L +AR
Sbjct: 396 ELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAR---- 451
Query: 535 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 693
+E+SR ++ E E+ V+SG A++ L++ L+ + S+++
Sbjct: 452 ------EELSR----LQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQM 494
Score = 44.8 bits (101), Expect = 3e-04
Identities = 39/157 (24%), Positives = 74/157 (47%), Gaps = 14/157 (8%)
Frame = +1
Query: 292 KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 471
K+L E+ L R+ +E+DL++ E+ ++ + Q N + L+ + Q
Sbjct: 333 KELDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQ 392
Query: 472 QDEERMD-------QLTNQLKEARL-LAEDADG----KSDEVSRK--LAFVEDELEVAED 609
Q +E +D QL QLKE R AE+A K++ S++ ++ E+EL A +
Sbjct: 393 QVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKARE 452
Query: 610 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ + +ELEE ++ L+ L+ + + Q +
Sbjct: 453 ELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEI 489
>AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein
protein.
Length = 2585
Score = 57.2 bits (132), Expect = 6e-08
Identities = 49/220 (22%), Positives = 109/220 (49%), Gaps = 9/220 (4%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
M + K++Q E + + D ++ ++++ E ++E+ K + EE+L +
Sbjct: 1403 MLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVA 1462
Query: 247 ----KNKLEQANK---DLEEKEKQLTATEAEVAALNRKVQ-QIEEDLEKSEERSGTAQQK 402
K + E N+ +L EKE +++ + ++ A+N K+Q +I+E EK E+ + +
Sbjct: 1463 HCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISE 1522
Query: 403 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 582
+ E + K ++ Q E +M +LTN+L+E++ + + +E+ R V
Sbjct: 1523 VQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKR----V 1578
Query: 583 EDELEVAEDRVKSGDAKI-SELEEELKVVGNSLKSLEVSE 699
++ L++ D++K +I ++++E + LK V+E
Sbjct: 1579 QEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNE 1618
Score = 46.8 bits (106), Expect = 8e-05
Identities = 45/183 (24%), Positives = 89/183 (48%), Gaps = 4/183 (2%)
Frame = +1
Query: 172 AEKVNEEVRELQKKLAQVEEDLILNKNKLEQ----ANKDLEEKEKQLTATEAEVAALNRK 339
+EK NE + +QK L + L K+++ A+ L+E+++ + V+ K
Sbjct: 1725 SEKTNE-ISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDK 1783
Query: 340 VQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA 519
+ +++DLE S + Q+K+ E + + + + K + N Q+ M+QL Q+K+
Sbjct: 1784 LSNMQKDLENSNAK---LQEKIQELKANEHQLITLKKDV-NETQKKVSEMEQLKKQIKDQ 1839
Query: 520 RLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSE 699
L + ++ +++KL + LE + +K D + +EE LK+ + LK + E
Sbjct: 1840 SLTLSKLEIENLNLAQKL---HENLEEMKSVMKERD-NLRRVEETLKLERDQLKE-SLQE 1894
Query: 700 EKA 708
KA
Sbjct: 1895 TKA 1897
Score = 45.6 bits (103), Expect = 2e-04
Identities = 42/178 (23%), Positives = 86/178 (48%), Gaps = 12/178 (6%)
Frame = +1
Query: 214 LAQVEEDLILNKNKLEQANKDLE----EKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 381
LA++E + + K +++ ++++ E++ T EA ++ + I E L K +E
Sbjct: 1303 LARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQE- 1361
Query: 382 SGTAQQKLLEAQQSADENNRMCKVLENRAQQD------EERMDQLTNQLKEARLLAEDAD 543
S + Q++ L ++ +E ++ +E +D E M L+ +L+E+ +
Sbjct: 1362 SQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVA 1421
Query: 544 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE--VSEEKAN 711
+ D++ R ++ E + ++ +K AK E EEELKV LK E ++E + N
Sbjct: 1422 KEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVN 1479
Score = 43.2 bits (97), Expect = 0.001
Identities = 41/203 (20%), Positives = 96/203 (47%), Gaps = 10/203 (4%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
+Q E++ +++E + + +E+L L ++L++ + + +++ E E+
Sbjct: 1036 QQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGEL 1095
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLE---NRAQQDEERMD 492
+ ++ ++EE L++ ++ QQ+LL Q+ E + +E N + E ++
Sbjct: 1096 SRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLE 1155
Query: 493 QL-TNQLKEARLLAED-ADGKSDEVSRK-LAFVEDELEVAEDRVKSGDAKIS----ELEE 651
+ T +L+ A+ L E+ + KS RK L ++ E D ++ +I + +E
Sbjct: 1156 HMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKE 1215
Query: 652 ELKVVGNSLKSLEVSEEKANQRV 720
ELK+ LK + + ++ + V
Sbjct: 1216 ELKIAHIHLKEHQETIDELRRSV 1238
Score = 41.9 bits (94), Expect = 0.002
Identities = 50/200 (25%), Positives = 91/200 (45%), Gaps = 3/200 (1%)
Frame = +1
Query: 124 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 303
+K QQ ++ + V EE+ E+QKK+ N++E +L+ KE L
Sbjct: 1107 EKLKEKSQQLQEKQQQLLNVQEEMSEMQKKI-----------NEIENLKNELKNKELTLE 1155
Query: 304 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE 483
E E L Q++ E+ E E +S T ++K+L+ Q + E R L ++ E
Sbjct: 1156 HMETERLEL---AQKLNENYE--EVKSITKERKVLKELQKSFETER--DHLRGYIREIEA 1208
Query: 484 RMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG---DAKISELEEE 654
Q +LK A + ++ DE+ R ++ ++ +D KS +I L EE
Sbjct: 1209 TGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEE 1268
Query: 655 LKVVGNSLKSLEVSEEKANQ 714
+++ N +K + ++E N+
Sbjct: 1269 QELLPN-VKEVSETQETMNE 1287
Score = 41.9 bits (94), Expect = 0.002
Identities = 44/210 (20%), Positives = 93/210 (44%), Gaps = 11/210 (5%)
Frame = +1
Query: 85 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE------DLILN 246
K+ M+ + +N+ K Q+ + + + ++V E QKK++++E+ D L
Sbjct: 1783 KLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLT 1842
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE--DLEKSEERSGTAQQKL--LEA 414
+KLE N +L +K + V ++++EE LE+ + + + K LE
Sbjct: 1843 LSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEI 1902
Query: 415 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 594
QQ + K + + E++ + T Q+ + + +D D DE+ +K ++
Sbjct: 1903 QQELKTARMLSKEHKETVDKLREKISEKTIQISD---IQKDLDKSKDELQKKQDRQNHQV 1959
Query: 595 EVAEDRVKSGDAKISE-LEEELKVVGNSLK 681
+ + + G ++E L E+ + LK
Sbjct: 1960 KPEKRLLSDGQQHLTESLREKCSRIKELLK 1989
Score = 38.3 bits (85), Expect = 0.028
Identities = 32/156 (20%), Positives = 73/156 (46%)
Frame = +1
Query: 175 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 354
E++N+E+ L K+ + + L K +L ++L+EK +++ E+ L +++ +
Sbjct: 821 ERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRD 880
Query: 355 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 534
L+ E +KL QQ+ +E + + ++ +Q +E + +QLK
Sbjct: 881 STLQTVEREKTLITEKL---QQTLEEVKTLTQEKDD-LKQLQESLQIERDQLKSD---IH 933
Query: 535 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE 642
D + + +L + L+ ++ + + +KISE
Sbjct: 934 DTVNMNIDTQEQLRNALESLKQHQETINTLKSKISE 969
Score = 34.7 bits (76), Expect = 0.34
Identities = 37/174 (21%), Positives = 76/174 (43%), Gaps = 2/174 (1%)
Frame = +1
Query: 175 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 354
EK+ +++ ++ QV N + N+ E +E+ T ++ + ++ ++
Sbjct: 2167 EKLKNGIQKENDRICQVNN--FFNNRIIAIMNESTEFEERSATISKE----WEQDLKSLK 2220
Query: 355 EDLEKSEERSGTAQQKLLEAQQ--SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 528
E EK + T + L Q ++N+ V Q E++ +L N L EA+
Sbjct: 2221 EKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEAK-- 2278
Query: 529 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
E A K ++ + ++ ELEV D + AK+ E + L+ +++ L+
Sbjct: 2279 -ESAMHKESKIIK----MQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQ 2327
>U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein.
Length = 3113
Score = 56.8 bits (131), Expect = 7e-08
Identities = 46/222 (20%), Positives = 101/222 (45%), Gaps = 14/222 (6%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL-------QKKLAQVE 228
+ +K+K Q ++ + + E + ++ + ++ +V EL Q+KL +E
Sbjct: 1981 EKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLE 2040
Query: 229 ED---LILNK----NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 387
+D L L K N++ Q NK+ E K+ + +A ++ + + + + LE + G
Sbjct: 2041 KDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKG 2100
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
+L Q+ + R + L R + DE++ + +LKE + K + + R
Sbjct: 2101 EFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLER 2160
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 693
+L E+ E+ ++ A++ L+ +++ + SLK E+
Sbjct: 2161 ELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFEL 2202
Score = 54.8 bits (126), Expect = 3e-07
Identities = 39/218 (17%), Positives = 96/218 (44%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 249
D++K K++ ++ E + + + A ++ E + ++ E+ + L E DL+ +
Sbjct: 2149 DSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLR 2208
Query: 250 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 429
++ E K ++EK+ QL+ + +++ +++ E+ + +E S TA + L + +
Sbjct: 2209 SEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELN 2268
Query: 430 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 609
E + + E+ +D + + R E + + +K V +L+ +E
Sbjct: 2269 EAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEH 2328
Query: 610 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
++ LE EL++ + + + E + VE
Sbjct: 2329 HADLLKGRVENLERELEIARTNQEHAALEAENSKGEVE 2366
Score = 49.2 bits (112), Expect = 1e-05
Identities = 43/209 (20%), Positives = 95/209 (45%), Gaps = 2/209 (0%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 261
+K + +EK+ ++K C + + ++ + + L++KL ++ EDL + E
Sbjct: 323 EKAKVELIEKEKVLNK---CRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAE 379
Query: 262 QANKDLEEKEKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 438
A LE+K K+ + E++ R Q ++++ + + R Q+L +A+ +
Sbjct: 380 SARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKAR---LTQELQQAKNMHNVLQ 436
Query: 439 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 618
L + QQ E +++ +L A + + K +E+ R + ++ E + + +
Sbjct: 437 AELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSE 496
Query: 619 SGDAKISELEEELKVVGNSL-KSLEVSEE 702
++ LE ELK + L +S +EE
Sbjct: 497 QKAREVCHLEAELKNIKQCLNQSQNFAEE 525
Score = 42.7 bits (96), Expect = 0.001
Identities = 40/222 (18%), Positives = 90/222 (40%), Gaps = 7/222 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++ A ++ + + ++ EK+N + + Q + + + E ++ Q++
Sbjct: 2191 EEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIK 2250
Query: 229 EDLILNKNKLEQANKDLEEK-------EKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 387
E+ L+ K+L E ++ + ATE + + Q+ +EK R
Sbjct: 2251 EESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLE 2310
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
++K L Q E+ +L+ R + E ++ + A L AE++ G+ + +
Sbjct: 2311 ADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKA 2370
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 693
K+ + L E V + ++ L EL+ + LE+
Sbjct: 2371 KIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEI 2412
Score = 38.7 bits (86), Expect = 0.021
Identities = 41/179 (22%), Positives = 86/179 (48%), Gaps = 16/179 (8%)
Frame = +1
Query: 190 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR-KVQQIE--ED 360
E++ ++KL EE L K +++ EE L AT + L + K+ ++
Sbjct: 2723 EIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQ 2782
Query: 361 LEKSEERSGTAQQKLLEA-QQSADENNRMCKVLEN-RAQQDEER--------MDQLTNQL 510
L+K ER+ + L+++ +Q +E + K L +A Q++++ +D+LT ++
Sbjct: 2783 LKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEI 2842
Query: 511 KEARLLAEDADGKSDEVSRK---LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL 678
KE + E+ ++DE K L ++LE A++ +++ A + + + G+ L
Sbjct: 2843 KELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQVAHLCSQQSKQDSRGSPL 2901
Score = 37.5 bits (83), Expect = 0.048
Identities = 40/176 (22%), Positives = 84/176 (47%), Gaps = 3/176 (1%)
Frame = +1
Query: 187 EEVRELQKKLAQVEEDL-ILNKNKLEQANKDLEE-KEKQLTATEAEVAALNRKVQQIEED 360
++++EL + +++++ L ++K+++E+ K EE E QL EAE +K Q + D
Sbjct: 2661 DQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAE-----KKHQALLLD 2715
Query: 361 LEKSEE-RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 537
K E T ++KL ++ +L++ ++ L N LK + E+
Sbjct: 2716 TNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEE-------LNNSLKATTQILEE 2768
Query: 538 ADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+ + + ++ E E A+ ++K +LEEE +++ L L+ ++EK
Sbjct: 2769 LKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEK 2824
Score = 37.1 bits (82), Expect = 0.064
Identities = 41/183 (22%), Positives = 87/183 (47%), Gaps = 1/183 (0%)
Frame = +1
Query: 166 LRAEKVNEE-VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 342
++AE++++ V E +++++++ED ++N + + LE KEK E+ LN KV
Sbjct: 867 MKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEK-------ELQLLNDKV 919
Query: 343 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 522
+ + ++++ ++ + + L E Q ++ + K + + ++ +++LT +E
Sbjct: 920 ETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELT---QENG 976
Query: 523 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 702
L E + E + E ++R KS ISEL ++ K L L+ EE
Sbjct: 977 TLKEINASLNQEKMNLIQKSESFANYIDEREKS----ISELSDQYK--QEKLILLQRCEE 1030
Query: 703 KAN 711
N
Sbjct: 1031 TGN 1033
Score = 36.7 bits (81), Expect = 0.084
Identities = 50/183 (27%), Positives = 91/183 (49%), Gaps = 15/183 (8%)
Frame = +1
Query: 82 KKMQAMKLEKDNAM-DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 258
++M+A ++ + D + QQ + +L EK+ V +L+K+ ++ L ++ +
Sbjct: 524 EEMKAKNTSQETMLRDLQEKINQQ--ENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHI 581
Query: 259 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ-QKLLEAQQSADEN 435
EQ N L + EK+ ++A ++AL K ++ E EK+ ++ +KLL +S EN
Sbjct: 582 EQLNDKLSKTEKE---SKALLSALELKKKEYELKEEKTLFSCWKSENEKLLTQMESEKEN 638
Query: 436 -----NRM--C-KVLENRAQQDEERMDQL----TNQLKEARLLAEDADGKSDEV-SRKLA 576
N + C K + ++ + ER+ L N E R L D KS EV ++KLA
Sbjct: 639 LQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLA 698
Query: 577 FVE 585
++E
Sbjct: 699 YME 701
Score = 36.3 bits (80), Expect = 0.11
Identities = 46/227 (20%), Positives = 94/227 (41%), Gaps = 9/227 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKL--EKDNA-MDKADTC-EQQARDANLRAEKVNEEVRELQKKL 216
+ +A ++A + +Q KL EKDN K C E++ ++ E+ + KK
Sbjct: 1914 EHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKT 1973
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 396
+++ K K ++ E + EAEV +Q + D+ + + Q
Sbjct: 1974 TALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQ 2033
Query: 397 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLA 576
+KL ++ + + LEN+ Q + + L + + + ++D + VS+ L
Sbjct: 2034 EKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALE 2093
Query: 577 FVEDELEVAEDRVKSGDAKISELE---EELKV--VGNSLKSLEVSEE 702
E R+ S ++ +L E+L+V + K L ++E+
Sbjct: 2094 AALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEK 2140
Score = 35.9 bits (79), Expect = 0.15
Identities = 31/164 (18%), Positives = 72/164 (43%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
EQ NL E + ++++ LQ K A +++ L + ++ + +LE + + +V
Sbjct: 2552 EQNLELRNLTVE-LEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKV 2610
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
+ K +++ ++ + +++ Q++L + E NR+ L+ ++ + DQL
Sbjct: 2611 NKMTAKETELQREMHEMAQKTAELQEEL------SGEKNRLAGELQLLLEEIKSSKDQLK 2664
Query: 502 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAK 633
E L + D + K V +E+ + R+ + K
Sbjct: 2665 ELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKK 2708
>U19769-1|AAA82889.1| 3210|Homo sapiens CENP-F kinetochore protein
protein.
Length = 3210
Score = 56.8 bits (131), Expect = 7e-08
Identities = 46/222 (20%), Positives = 101/222 (45%), Gaps = 14/222 (6%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL-------QKKLAQVE 228
+ +K+K Q ++ + + E + ++ + ++ +V EL Q+KL +E
Sbjct: 2078 EKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLE 2137
Query: 229 ED---LILNK----NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 387
+D L L K N++ Q NK+ E K+ + +A ++ + + + + LE + G
Sbjct: 2138 KDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKG 2197
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
+L Q+ + R + L R + DE++ + +LKE + K + + R
Sbjct: 2198 EFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLER 2257
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 693
+L E+ E+ ++ A++ L+ +++ + SLK E+
Sbjct: 2258 ELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFEL 2299
Score = 54.8 bits (126), Expect = 3e-07
Identities = 39/218 (17%), Positives = 96/218 (44%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 249
D++K K++ ++ E + + + A ++ E + ++ E+ + L E DL+ +
Sbjct: 2246 DSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLR 2305
Query: 250 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 429
++ E K ++EK+ QL+ + +++ +++ E+ + +E S TA + L + +
Sbjct: 2306 SEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELN 2365
Query: 430 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 609
E + + E+ +D + + R E + + +K V +L+ +E
Sbjct: 2366 EAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEH 2425
Query: 610 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
++ LE EL++ + + + E + VE
Sbjct: 2426 HADLLKGRVENLERELEIARTNQEHAALEAENSKGEVE 2463
Score = 49.2 bits (112), Expect = 1e-05
Identities = 43/209 (20%), Positives = 95/209 (45%), Gaps = 2/209 (0%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 261
+K + +EK+ ++K C + + ++ + + L++KL ++ EDL + E
Sbjct: 323 EKAKVELIEKEKVLNK---CRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAE 379
Query: 262 QANKDLEEKEKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 438
A LE+K K+ + E++ R Q ++++ + + R Q+L +A+ +
Sbjct: 380 SARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKAR---LTQELQQAKNMHNVLQ 436
Query: 439 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 618
L + QQ E +++ +L A + + K +E+ R + ++ E + + +
Sbjct: 437 AELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSE 496
Query: 619 SGDAKISELEEELKVVGNSL-KSLEVSEE 702
++ LE ELK + L +S +EE
Sbjct: 497 QKAREVCHLEAELKNIKQCLNQSQNFAEE 525
Score = 43.6 bits (98), Expect = 7e-04
Identities = 40/222 (18%), Positives = 91/222 (40%), Gaps = 7/222 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++ A ++ + + ++ EK+N + + Q + + + E ++ Q++
Sbjct: 2288 EEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIK 2347
Query: 229 EDLILNKNKLEQANKDLEEK-------EKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 387
E+ L+ K+L E ++ + ATE + + Q+ +EK R
Sbjct: 2348 EESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLE 2407
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
++K L Q E+ +L+ R + E ++ + A L AE++ G+ + +
Sbjct: 2408 ADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKA 2467
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 693
K+ + L E V + ++ +L EL+ + LE+
Sbjct: 2468 KIEGMTQSLRGLELDVVTIRSEKEDLTNELQKEQERISELEI 2509
Score = 38.7 bits (86), Expect = 0.021
Identities = 41/179 (22%), Positives = 86/179 (48%), Gaps = 16/179 (8%)
Frame = +1
Query: 190 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR-KVQQIE--ED 360
E++ ++KL EE L K +++ EE L AT + L + K+ ++
Sbjct: 2820 EIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQ 2879
Query: 361 LEKSEERSGTAQQKLLEA-QQSADENNRMCKVLEN-RAQQDEER--------MDQLTNQL 510
L+K ER+ + L+++ +Q +E + K L +A Q++++ +D+LT ++
Sbjct: 2880 LKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEI 2939
Query: 511 KEARLLAEDADGKSDEVSRK---LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL 678
KE + E+ ++DE K L ++LE A++ +++ A + + + G+ L
Sbjct: 2940 KELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQVAHLCSQQSKQDSRGSPL 2998
Score = 37.5 bits (83), Expect = 0.048
Identities = 51/184 (27%), Positives = 91/184 (49%), Gaps = 16/184 (8%)
Frame = +1
Query: 82 KKMQAMKLEKDNAM-DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 258
++M+A ++ + D + QQ + +L EK+ V +L+K+ ++ L ++ +
Sbjct: 524 EEMKAKNTSQETMLRDLQEKINQQ--ENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHI 581
Query: 259 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEAQQSADE 432
EQ N L + EK+ ++A ++AL K ++ EE E+ S + +KLL +S E
Sbjct: 582 EQLNDKLSKTEKE---SKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKE 638
Query: 433 N-----NRM--C-KVLENRAQQDEERMDQL----TNQLKEARLLAEDADGKSDEV-SRKL 573
N N + C K + ++ + ER+ L N E R L D KS EV ++KL
Sbjct: 639 NLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKL 698
Query: 574 AFVE 585
A++E
Sbjct: 699 AYME 702
Score = 37.5 bits (83), Expect = 0.048
Identities = 40/176 (22%), Positives = 84/176 (47%), Gaps = 3/176 (1%)
Frame = +1
Query: 187 EEVRELQKKLAQVEEDL-ILNKNKLEQANKDLEE-KEKQLTATEAEVAALNRKVQQIEED 360
++++EL + +++++ L ++K+++E+ K EE E QL EAE +K Q + D
Sbjct: 2758 DQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAE-----KKHQALLLD 2812
Query: 361 LEKSEE-RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 537
K E T ++KL ++ +L++ ++ L N LK + E+
Sbjct: 2813 TNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEE-------LNNSLKATTQILEE 2865
Query: 538 ADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+ + + ++ E E A+ ++K +LEEE +++ L L+ ++EK
Sbjct: 2866 LKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEK 2921
Score = 37.1 bits (82), Expect = 0.064
Identities = 41/183 (22%), Positives = 87/183 (47%), Gaps = 1/183 (0%)
Frame = +1
Query: 166 LRAEKVNEE-VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 342
++AE++++ V E +++++++ED ++N + + LE KEK E+ LN KV
Sbjct: 868 MKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEK-------ELQLLNDKV 920
Query: 343 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 522
+ + ++++ ++ + + L E Q ++ + K + + ++ +++LT +E
Sbjct: 921 ETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELT---QENG 977
Query: 523 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 702
L E + E + E ++R KS ISEL ++ K L L+ EE
Sbjct: 978 TLKEINASLNQEKMNLIQKSESFANYIDEREKS----ISELSDQYK--QEKLILLQRCEE 1031
Query: 703 KAN 711
N
Sbjct: 1032 TGN 1034
Score = 36.3 bits (80), Expect = 0.11
Identities = 46/227 (20%), Positives = 94/227 (41%), Gaps = 9/227 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKL--EKDNA-MDKADTC-EQQARDANLRAEKVNEEVRELQKKL 216
+ +A ++A + +Q KL EKDN K C E++ ++ E+ + KK
Sbjct: 2011 EHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKT 2070
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 396
+++ K K ++ E + EAEV +Q + D+ + + Q
Sbjct: 2071 TALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQ 2130
Query: 397 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLA 576
+KL ++ + + LEN+ Q + + L + + + ++D + VS+ L
Sbjct: 2131 EKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALE 2190
Query: 577 FVEDELEVAEDRVKSGDAKISELE---EELKV--VGNSLKSLEVSEE 702
E R+ S ++ +L E+L+V + K L ++E+
Sbjct: 2191 AALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEK 2237
Score = 35.9 bits (79), Expect = 0.15
Identities = 31/164 (18%), Positives = 72/164 (43%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
EQ NL E + ++++ LQ K A +++ L + ++ + +LE + + +V
Sbjct: 2649 EQNLELRNLTVE-LEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKV 2707
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
+ K +++ ++ + +++ Q++L + E NR+ L+ ++ + DQL
Sbjct: 2708 NKMTAKETELQREMHEMAQKTAELQEEL------SGEKNRLAGELQLLLEEIKSSKDQLK 2761
Query: 502 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAK 633
E L + D + K V +E+ + R+ + K
Sbjct: 2762 ELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKK 2805
>L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated protein
protein.
Length = 1410
Score = 56.8 bits (131), Expect = 7e-08
Identities = 51/215 (23%), Positives = 106/215 (49%), Gaps = 13/215 (6%)
Frame = +1
Query: 112 DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK---LEQANKDLE 282
D A + Q+ + ++V ++++ Q+ +Q+E L K K LEQ ++LE
Sbjct: 670 DTAQNALQDKHQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELE 729
Query: 283 EKEKQLTATEAEV-AALNRKVQQIEED--LEKSEERSGTAQQKLLEAQQSADENNRMCKV 453
+ K+L A EV A+ + +Q +++ L E T K LE ++ + R+
Sbjct: 730 GQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLD-- 787
Query: 454 LENRAQQDEERMDQLTNQLKEARLLAEDADGKS-------DEVSRKLAFVEDELEVAEDR 612
L+ +++ E +LT Q +E ++L +D + S +E++ ++ EL+ +
Sbjct: 788 LQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKME 847
Query: 613 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
++ ++S ++++L V +SLK+ + EK NQ+
Sbjct: 848 KEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQK 882
Score = 51.6 bits (118), Expect = 3e-06
Identities = 50/231 (21%), Positives = 110/231 (47%), Gaps = 12/231 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR----ELQKKL 216
Q+K+ +++IK+K+ + EK +T Q+ + ++ E++N ++ ELQK
Sbjct: 789 QKKSEALESIKQKLTKQEEEKQILKQDFETLSQETK---IQHEELNNRIQTTVTELQKVK 845
Query: 217 AQVE---EDLILNKNKLEQANKDLE----EKEKQLTATEAEVAALNRKVQQIEEDLEKSE 375
+ E +L K+KL + + L+ E EK+ +A + L + ++++ L+
Sbjct: 846 MEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQM 905
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
E + Q++L ++ + E + K+ N Q E++ Q N LK+ + G +
Sbjct: 906 ENTLKEQKELKKSLEKEKEASHQLKLELNSMQ---EQLIQAQNTLKQNEKEEQQLQGNIN 962
Query: 556 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL-KVVGNSLKSLEVSEEK 705
E+ + + ++E + +K + +ELE +L + + + + L +EK
Sbjct: 963 ELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEK 1013
Score = 51.2 bits (117), Expect = 4e-06
Identities = 40/209 (19%), Positives = 99/209 (47%), Gaps = 7/209 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
Q K ++ I ++ + + + + E ++ + + ++ EL+ ++ ++E
Sbjct: 677 QDKHQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLE 736
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE-------DLEKSEERSG 387
D + K EQA +DL+++ + T E L+++++ +E DL+K E
Sbjct: 737 ADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALE 796
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
+ +QKL + + +E + + E +Q+ + + ++L N+++ + + + +
Sbjct: 797 SIKQKLTKQE---EEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMT 853
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEE 654
+L+ V+D+L D +K+ SE E+E
Sbjct: 854 ELSTVKDKLSKVSDSLKNSK---SEFEKE 879
Score = 51.2 bits (117), Expect = 4e-06
Identities = 35/184 (19%), Positives = 79/184 (42%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
K ++ K E + + + E +LQ++L Q ++L K K+ + E+
Sbjct: 965 KQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKS 1024
Query: 289 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRA 468
++ +++ ++ +DL+ EE+ AQ+ L+ + N++ + L+
Sbjct: 1025 QETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAK 1084
Query: 469 QQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE 648
E+ + QL+E +D + ++L + +L E+ + +I++L
Sbjct: 1085 ATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLN 1144
Query: 649 EELK 660
EELK
Sbjct: 1145 EELK 1148
Score = 50.0 bits (114), Expect = 8e-06
Identities = 49/210 (23%), Positives = 102/210 (48%), Gaps = 12/210 (5%)
Frame = +1
Query: 55 KAATMD---AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQV 225
KAA +D K+ ++++ +N + + ++ + ++ E+ +Q++L Q
Sbjct: 884 KAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQA 943
Query: 226 EEDLILNKNKLEQANKDL-------EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS 384
+ L N+ + +Q ++ E+K+KQ+ A + E+ K+ L+K+E +
Sbjct: 944 QNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGEL-----KIAV----LQKTELEN 994
Query: 385 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL--KEARLLAEDADGKSDE 558
QQ AQ+ A E ++ VL+N ++ +E QL + +E+ LLA D KS
Sbjct: 995 KLQQQLTQAAQELAAEKEKI-SVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKS-- 1051
Query: 559 VSRKLAFVEDELEVAEDRVKSGDAKISELE 648
V KL+ +++L +++ + + I EL+
Sbjct: 1052 VEEKLSLAQEDLISNRNQIGNQNKLIQELK 1081
Score = 47.6 bits (108), Expect = 4e-05
Identities = 42/227 (18%), Positives = 100/227 (44%), Gaps = 3/227 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKV---NEEVRELQKKLA 219
+Q + + ++ + LE + + +A ++ R L +EK+ ++V +LQ KL+
Sbjct: 406 EQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQ--LSSEKLMDKEQQVADLQLKLS 463
Query: 220 QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 399
++EE L + L++ ++Q +A + K+++ + DLE+ + G Q
Sbjct: 464 RLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGEKDQ 523
Query: 400 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 579
K+ + ++ +LE + ++ + L E DEV++
Sbjct: 524 KIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQDEVTQLTEN 583
Query: 580 VEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
V+++ E + ++ ++ E + L+ + + SLE S + N ++
Sbjct: 584 VKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQL 630
Score = 47.2 bits (107), Expect = 6e-05
Identities = 50/214 (23%), Positives = 93/214 (43%), Gaps = 2/214 (0%)
Frame = +1
Query: 88 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL-ILNKNKLEQ 264
MQ ++ N + + + EQQ + N+ K + E ++ Q + Q E + +L K +LE
Sbjct: 936 MQEQLIQAQNTLKQNEKEEQQLQ-GNINELKQSSEQKKKQIEALQGELKIAVLQKTELE- 993
Query: 265 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 444
NK ++QLT E+AA K+ ++ + EKS+E Q + +
Sbjct: 994 -NK----LQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQD 1048
Query: 445 CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS- 621
K +E + +E + NQ+ L ++ + + A E +L ++R K+
Sbjct: 1049 LKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQL---QERCKAL 1105
Query: 622 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
D + + +E ++V K E+ E K Q E
Sbjct: 1106 QDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKE 1139
Score = 43.6 bits (98), Expect = 7e-04
Identities = 37/166 (22%), Positives = 73/166 (43%), Gaps = 1/166 (0%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAMDKADTC-EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
K+ + KLE D EQ+ R+ + ++V +E EL+K+ + E L
Sbjct: 1165 KQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKL------ 1218
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
+ +++EKE + E A L ++ + E+L ++ ++Q+++ E ++ D+
Sbjct: 1219 ----HSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDL 1274
Query: 436 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 573
VLE Q +++ L + + E K E+ RKL
Sbjct: 1275 RGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKL 1320
Score = 40.3 bits (90), Expect = 0.007
Identities = 33/189 (17%), Positives = 80/189 (42%), Gaps = 4/189 (2%)
Frame = +1
Query: 148 QARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAA 327
Q D + +++ ++L ++ L KL+ + + E L + + +
Sbjct: 661 QRADLQNHLDTAQNALQDKHQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLS 720
Query: 328 LNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQ 507
L +K +++E ++K E S + +A Q + ++ LE RA + ++++
Sbjct: 721 LEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEI 780
Query: 508 LKEARLLAEDADGKSDEVSRKLAFVEDELEVAED--RVKSGDAKI--SELEEELKVVGNS 675
+ RL + + + +KL E+E ++ + S + KI EL ++
Sbjct: 781 VSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTE 840
Query: 676 LKSLEVSEE 702
L+ +++ +E
Sbjct: 841 LQKVKMEKE 849
Score = 39.9 bits (89), Expect = 0.009
Identities = 33/191 (17%), Positives = 84/191 (43%), Gaps = 7/191 (3%)
Frame = +1
Query: 172 AEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI 351
+EK+ +E ++ + + A E + +++L + +++ ++L ++ V L +K Q +
Sbjct: 248 SEKLKDESKKFESQYASSEATISQLRSELSKGPQEVRVYVQELQKLKSSVNELTQKNQTL 307
Query: 352 -------EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL 510
E+D K EE+ Q + + + C+ L++R E + ++ +L
Sbjct: 308 TENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVEL 367
Query: 511 KEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
E + + EV K ++ E + + + + + +L+ E+ + + L E
Sbjct: 368 SEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETE 427
Query: 691 VSEEKANQRVE 723
+A+ R++
Sbjct: 428 RQLGEAHGRLK 438
>AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting citron
kinase protein.
Length = 2027
Score = 56.8 bits (131), Expect = 7e-08
Identities = 55/231 (23%), Positives = 102/231 (44%), Gaps = 10/231 (4%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 240
A +++KK+ E ++ DK EQ+ + R +V + + + +L E
Sbjct: 442 AKTSSMEKKLLIKSKELQDSQDKCHKMEQEMTRLHRRVSEVEAVLSQKEVELKASETQRS 501
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
L + L + ++ L EV+ + K Q+ D+ + + +++ E Q
Sbjct: 502 LLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIKEQ--EYQA 559
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE--L 594
+E M LE R D ++L+E+RL AE+ K+ E KL +D+
Sbjct: 560 QVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKATECQHKLLKAKDQGKP 619
Query: 595 EVAE----DRVKS-GDAKISELEEEL-KVVGNSLKSLEVSE--EKANQRVE 723
EV E +++ + KI EL+E+L K V S ++ E+ + +A +R E
Sbjct: 620 EVGEYAKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAE 670
Score = 52.0 bits (119), Expect = 2e-06
Identities = 59/237 (24%), Positives = 105/237 (44%), Gaps = 19/237 (8%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-------VRELQKKLAQV 225
M A ++ + ++ +K +A E Q R + EK++ + + EL+ +L +V
Sbjct: 802 MKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREV 861
Query: 226 ----EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 393
EE + K +L + L+E+E QLTA +A AAL +++Q + +LE++ +
Sbjct: 862 SLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEE 921
Query: 394 QQKLL----EAQQSADENNRMCKV---LENRAQQDEERMDQLTNQLKEARLLAEDADGKS 552
Q L E Q+ D C V LE + Q E +L NQ ++A G +
Sbjct: 922 IQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGAN 981
Query: 553 DEVSRKLAFVED-ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
DE+ + + V+ E+ E ++ K + E LK L+ + E N +
Sbjct: 982 DEIVQLRSEVDHLRREITEREMQLTSQK--QTMEALKTTCTMLEEQVMDLEALNDEL 1036
Score = 48.4 bits (110), Expect = 3e-05
Identities = 47/208 (22%), Positives = 98/208 (47%), Gaps = 4/208 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
Q+ A ++ ++ M ++ + +A ++D E + R++ L AE+ + E Q KL + +
Sbjct: 555 QEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKATECQHKLLKAK 614
Query: 229 EDLILNKNKL-EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
+ K ++ E A + E+QL K+Q+++E LEK+ + S A + L
Sbjct: 615 DQ---GKPEVGEYAKLEKINAEQQL------------KIQELQEKLEKAVKASTEATELL 659
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQL--TNQLKEARLLAE-DADGKSDEVSRKLA 576
+Q+ + R + L+NR E +L +L+E A+ A + +K
Sbjct: 660 QNIRQAKERAERELEKLQNREDSSEGIRKKLVEAEELEEKHREAQVSAQHLEVHLKQKEQ 719
Query: 577 FVEDELEVAEDRVKSGDAKISELEEELK 660
E++++V ++++K A LE ++
Sbjct: 720 HYEEKIKVLDNQIKKDLADKETLENMMQ 747
Score = 44.4 bits (100), Expect = 4e-04
Identities = 56/243 (23%), Positives = 110/243 (45%), Gaps = 18/243 (7%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEK-----VNEEVRELQKK 213
++K +D KK A K +N M + + E + L +K ++ ++R L+++
Sbjct: 722 EEKIKVLDNQIKKDLADKETLENMMQRHEE-EAHEKGKILSEQKAMINAMDSKIRSLEQR 780
Query: 214 LAQVEE--DLILNKNKLEQANKDLEEK-----EKQLTATEAEVAALNRKVQQIEEDLEKS 372
+ ++ E L N + Q N +E+ +Q E + L + +++EE LEK
Sbjct: 781 IVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKI 840
Query: 373 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD----QLTNQLKEARLLAEDA 540
+ + + +LLE + E + LE+ Q+ E + QL+ Q +E++L A A
Sbjct: 841 SHQDHSDKNRLLELETRLREVS-----LEHEEQKLELKRQLTELQLSLQERESQLTALQA 895
Query: 541 DGKSDEVSRKLA--FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
+ E + A +E+ AE+ +++ A E++ + + NS + EE+ NQ
Sbjct: 896 ARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQ 955
Query: 715 RVE 723
E
Sbjct: 956 LTE 958
Score = 38.3 bits (85), Expect = 0.028
Identities = 52/234 (22%), Positives = 108/234 (46%), Gaps = 11/234 (4%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
Q +A I + Q ++L + +Q ++ L+AE +++++ +L+KK A +E
Sbjct: 1073 QSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLE 1132
Query: 229 EDLILNKNKLEQ----ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE----ERS 384
+ + KLE + LEE+ K + + + R Q ++E L++++ ERS
Sbjct: 1133 MNARSLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERS 1192
Query: 385 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE-- 558
Q LE Q + ++ +E Q + +D L ++ + + + E
Sbjct: 1193 DLEYQ--LENIQVLYSHEKV--KMEGTISQQTKLIDFLQAKMDQPAKKKKGLFSRRKEDP 1248
Query: 559 -VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+ ++ +EL++A ++ K A+ +ELEE L+ L+S EE A+++
Sbjct: 1249 ALPTQVPLQYNELKLALEKEK---ARCAELEEALQKTRIELRS--AREEAAHRK 1297
>AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F,
350/400ka (mitosin) protein.
Length = 3114
Score = 56.8 bits (131), Expect = 7e-08
Identities = 46/222 (20%), Positives = 101/222 (45%), Gaps = 14/222 (6%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL-------QKKLAQVE 228
+ +K+K Q ++ + + E + ++ + ++ +V EL Q+KL +E
Sbjct: 1982 EKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLE 2041
Query: 229 ED---LILNK----NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 387
+D L L K N++ Q NK+ E K+ + +A ++ + + + + LE + G
Sbjct: 2042 KDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKG 2101
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
+L Q+ + R + L R + DE++ + +LKE + K + + R
Sbjct: 2102 EFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLER 2161
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 693
+L E+ E+ ++ A++ L+ +++ + SLK E+
Sbjct: 2162 ELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFEL 2203
Score = 54.8 bits (126), Expect = 3e-07
Identities = 39/218 (17%), Positives = 96/218 (44%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 249
D++K K++ ++ E + + + A ++ E + ++ E+ + L E DL+ +
Sbjct: 2150 DSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLR 2209
Query: 250 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 429
++ E K ++EK+ QL+ + +++ +++ E+ + +E S TA + L + +
Sbjct: 2210 SEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELN 2269
Query: 430 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 609
E + + E+ +D + + R E + + +K V +L+ +E
Sbjct: 2270 EAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEH 2329
Query: 610 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
++ LE EL++ + + + E + VE
Sbjct: 2330 HADLLKGRVENLERELEIARTNQEHAALEAENSKGEVE 2367
Score = 49.2 bits (112), Expect = 1e-05
Identities = 43/209 (20%), Positives = 95/209 (45%), Gaps = 2/209 (0%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 261
+K + +EK+ ++K C + + ++ + + L++KL ++ EDL + E
Sbjct: 323 EKAKVELIEKEKVLNK---CRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAE 379
Query: 262 QANKDLEEKEKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 438
A LE+K K+ + E++ R Q ++++ + + R Q+L +A+ +
Sbjct: 380 SARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKAR---LTQELQQAKNMHNVLQ 436
Query: 439 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 618
L + QQ E +++ +L A + + K +E+ R + ++ E + + +
Sbjct: 437 AELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSE 496
Query: 619 SGDAKISELEEELKVVGNSL-KSLEVSEE 702
++ LE ELK + L +S +EE
Sbjct: 497 QKAREVCHLEAELKNIKQCLNQSQNFAEE 525
Score = 42.7 bits (96), Expect = 0.001
Identities = 40/222 (18%), Positives = 90/222 (40%), Gaps = 7/222 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++ A ++ + + ++ EK+N + + Q + + + E ++ Q++
Sbjct: 2192 EEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIK 2251
Query: 229 EDLILNKNKLEQANKDLEEK-------EKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 387
E+ L+ K+L E ++ + ATE + + Q+ +EK R
Sbjct: 2252 EESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLE 2311
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
++K L Q E+ +L+ R + E ++ + A L AE++ G+ + +
Sbjct: 2312 ADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKA 2371
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 693
K+ + L E V + ++ L EL+ + LE+
Sbjct: 2372 KIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEI 2413
Score = 38.7 bits (86), Expect = 0.021
Identities = 41/179 (22%), Positives = 86/179 (48%), Gaps = 16/179 (8%)
Frame = +1
Query: 190 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR-KVQQIE--ED 360
E++ ++KL EE L K +++ EE L AT + L + K+ ++
Sbjct: 2724 EIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQ 2783
Query: 361 LEKSEERSGTAQQKLLEA-QQSADENNRMCKVLEN-RAQQDEER--------MDQLTNQL 510
L+K ER+ + L+++ +Q +E + K L +A Q++++ +D+LT ++
Sbjct: 2784 LKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEI 2843
Query: 511 KEARLLAEDADGKSDEVSRK---LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL 678
KE + E+ ++DE K L ++LE A++ +++ A + + + G+ L
Sbjct: 2844 KELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQVAHLCSQQSKQDSRGSPL 2902
Score = 37.5 bits (83), Expect = 0.048
Identities = 51/184 (27%), Positives = 91/184 (49%), Gaps = 16/184 (8%)
Frame = +1
Query: 82 KKMQAMKLEKDNAM-DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 258
++M+A ++ + D + QQ + +L EK+ V +L+K+ ++ L ++ +
Sbjct: 524 EEMKAKNTSQETMLRDLQEKINQQ--ENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHI 581
Query: 259 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEAQQSADE 432
EQ N L + EK+ ++A ++AL K ++ EE E+ S + +KLL +S E
Sbjct: 582 EQLNDKLSKTEKE---SKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKE 638
Query: 433 N-----NRM--C-KVLENRAQQDEERMDQL----TNQLKEARLLAEDADGKSDEV-SRKL 573
N N + C K + ++ + ER+ L N E R L D KS EV ++KL
Sbjct: 639 NLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKL 698
Query: 574 AFVE 585
A++E
Sbjct: 699 AYME 702
Score = 37.5 bits (83), Expect = 0.048
Identities = 40/176 (22%), Positives = 84/176 (47%), Gaps = 3/176 (1%)
Frame = +1
Query: 187 EEVRELQKKLAQVEEDL-ILNKNKLEQANKDLEE-KEKQLTATEAEVAALNRKVQQIEED 360
++++EL + +++++ L ++K+++E+ K EE E QL EAE +K Q + D
Sbjct: 2662 DQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAE-----KKHQALLLD 2716
Query: 361 LEKSEE-RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 537
K E T ++KL ++ +L++ ++ L N LK + E+
Sbjct: 2717 TNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEE-------LNNSLKATTQILEE 2769
Query: 538 ADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+ + + ++ E E A+ ++K +LEEE +++ L L+ ++EK
Sbjct: 2770 LKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEK 2825
Score = 37.1 bits (82), Expect = 0.064
Identities = 41/183 (22%), Positives = 87/183 (47%), Gaps = 1/183 (0%)
Frame = +1
Query: 166 LRAEKVNEE-VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 342
++AE++++ V E +++++++ED ++N + + LE KEK E+ LN KV
Sbjct: 868 MKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEK-------ELQLLNDKV 920
Query: 343 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 522
+ + ++++ ++ + + L E Q ++ + K + + ++ +++LT +E
Sbjct: 921 ETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELT---QENG 977
Query: 523 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 702
L E + E + E ++R KS ISEL ++ K L L+ EE
Sbjct: 978 TLKEINASLNQEKMNLIQKSESFANYIDEREKS----ISELSDQYK--QEKLILLQRCEE 1031
Query: 703 KAN 711
N
Sbjct: 1032 TGN 1034
Score = 36.3 bits (80), Expect = 0.11
Identities = 46/227 (20%), Positives = 94/227 (41%), Gaps = 9/227 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKL--EKDNA-MDKADTC-EQQARDANLRAEKVNEEVRELQKKL 216
+ +A ++A + +Q KL EKDN K C E++ ++ E+ + KK
Sbjct: 1915 EHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKT 1974
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 396
+++ K K ++ E + EAEV +Q + D+ + + Q
Sbjct: 1975 TALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQ 2034
Query: 397 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLA 576
+KL ++ + + LEN+ Q + + L + + + ++D + VS+ L
Sbjct: 2035 EKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALE 2094
Query: 577 FVEDELEVAEDRVKSGDAKISELE---EELKV--VGNSLKSLEVSEE 702
E R+ S ++ +L E+L+V + K L ++E+
Sbjct: 2095 AALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEK 2141
Score = 35.9 bits (79), Expect = 0.15
Identities = 31/164 (18%), Positives = 72/164 (43%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
EQ NL E + ++++ LQ K A +++ L + ++ + +LE + + +V
Sbjct: 2553 EQNLELRNLTVE-LEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKV 2611
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
+ K +++ ++ + +++ Q++L + E NR+ L+ ++ + DQL
Sbjct: 2612 NKMTAKETELQREMHEMAQKTAELQEEL------SGEKNRLAGELQLLLEEIKSSKDQLK 2665
Query: 502 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAK 633
E L + D + K V +E+ + R+ + K
Sbjct: 2666 ELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKK 2709
>AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F,
350/400ka (mitosin) protein.
Length = 3114
Score = 56.8 bits (131), Expect = 7e-08
Identities = 46/222 (20%), Positives = 101/222 (45%), Gaps = 14/222 (6%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL-------QKKLAQVE 228
+ +K+K Q ++ + + E + ++ + ++ +V EL Q+KL +E
Sbjct: 1982 EKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLE 2041
Query: 229 ED---LILNK----NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 387
+D L L K N++ Q NK+ E K+ + +A ++ + + + + LE + G
Sbjct: 2042 KDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKG 2101
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
+L Q+ + R + L R + DE++ + +LKE + K + + R
Sbjct: 2102 EFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLER 2161
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 693
+L E+ E+ ++ A++ L+ +++ + SLK E+
Sbjct: 2162 ELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFEL 2203
Score = 54.8 bits (126), Expect = 3e-07
Identities = 39/218 (17%), Positives = 96/218 (44%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 249
D++K K++ ++ E + + + A ++ E + ++ E+ + L E DL+ +
Sbjct: 2150 DSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLR 2209
Query: 250 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 429
++ E K ++EK+ QL+ + +++ +++ E+ + +E S TA + L + +
Sbjct: 2210 SEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELN 2269
Query: 430 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 609
E + + E+ +D + + R E + + +K V +L+ +E
Sbjct: 2270 EAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEH 2329
Query: 610 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
++ LE EL++ + + + E + VE
Sbjct: 2330 HADLLKGRVENLERELEIARTNQEHAALEAENSKGEVE 2367
Score = 49.2 bits (112), Expect = 1e-05
Identities = 43/209 (20%), Positives = 95/209 (45%), Gaps = 2/209 (0%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 261
+K + +EK+ ++K C + + ++ + + L++KL ++ EDL + E
Sbjct: 323 EKAKVELIEKEKVLNK---CRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAE 379
Query: 262 QANKDLEEKEKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 438
A LE+K K+ + E++ R Q ++++ + + R Q+L +A+ +
Sbjct: 380 SARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKAR---LTQELQQAKNMHNVLQ 436
Query: 439 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 618
L + QQ E +++ +L A + + K +E+ R + ++ E + + +
Sbjct: 437 AELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSE 496
Query: 619 SGDAKISELEEELKVVGNSL-KSLEVSEE 702
++ LE ELK + L +S +EE
Sbjct: 497 QKAREVCHLEAELKNIKQCLNQSQNFAEE 525
Score = 42.7 bits (96), Expect = 0.001
Identities = 40/222 (18%), Positives = 90/222 (40%), Gaps = 7/222 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++ A ++ + + ++ EK+N + + Q + + + E ++ Q++
Sbjct: 2192 EEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIK 2251
Query: 229 EDLILNKNKLEQANKDLEEK-------EKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 387
E+ L+ K+L E ++ + ATE + + Q+ +EK R
Sbjct: 2252 EESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLE 2311
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
++K L Q E+ +L+ R + E ++ + A L AE++ G+ + +
Sbjct: 2312 ADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKA 2371
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 693
K+ + L E V + ++ L EL+ + LE+
Sbjct: 2372 KIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEI 2413
Score = 38.7 bits (86), Expect = 0.021
Identities = 41/179 (22%), Positives = 86/179 (48%), Gaps = 16/179 (8%)
Frame = +1
Query: 190 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR-KVQQIE--ED 360
E++ ++KL EE L K +++ EE L AT + L + K+ ++
Sbjct: 2724 EIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQ 2783
Query: 361 LEKSEERSGTAQQKLLEA-QQSADENNRMCKVLEN-RAQQDEER--------MDQLTNQL 510
L+K ER+ + L+++ +Q +E + K L +A Q++++ +D+LT ++
Sbjct: 2784 LKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEI 2843
Query: 511 KEARLLAEDADGKSDEVSRK---LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL 678
KE + E+ ++DE K L ++LE A++ +++ A + + + G+ L
Sbjct: 2844 KELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQVAHLCSQQSKQDSRGSPL 2902
Score = 37.5 bits (83), Expect = 0.048
Identities = 51/184 (27%), Positives = 91/184 (49%), Gaps = 16/184 (8%)
Frame = +1
Query: 82 KKMQAMKLEKDNAM-DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 258
++M+A ++ + D + QQ + +L EK+ V +L+K+ ++ L ++ +
Sbjct: 524 EEMKAKNTSQETMLRDLQEKINQQ--ENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHI 581
Query: 259 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEAQQSADE 432
EQ N L + EK+ ++A ++AL K ++ EE E+ S + +KLL +S E
Sbjct: 582 EQLNDKLSKTEKE---SKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKE 638
Query: 433 N-----NRM--C-KVLENRAQQDEERMDQL----TNQLKEARLLAEDADGKSDEV-SRKL 573
N N + C K + ++ + ER+ L N E R L D KS EV ++KL
Sbjct: 639 NLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKL 698
Query: 574 AFVE 585
A++E
Sbjct: 699 AYME 702
Score = 37.5 bits (83), Expect = 0.048
Identities = 40/176 (22%), Positives = 84/176 (47%), Gaps = 3/176 (1%)
Frame = +1
Query: 187 EEVRELQKKLAQVEEDL-ILNKNKLEQANKDLEE-KEKQLTATEAEVAALNRKVQQIEED 360
++++EL + +++++ L ++K+++E+ K EE E QL EAE +K Q + D
Sbjct: 2662 DQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAE-----KKHQALLLD 2716
Query: 361 LEKSEE-RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 537
K E T ++KL ++ +L++ ++ L N LK + E+
Sbjct: 2717 TNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEE-------LNNSLKATTQILEE 2769
Query: 538 ADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+ + + ++ E E A+ ++K +LEEE +++ L L+ ++EK
Sbjct: 2770 LKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEK 2825
Score = 37.1 bits (82), Expect = 0.064
Identities = 41/183 (22%), Positives = 87/183 (47%), Gaps = 1/183 (0%)
Frame = +1
Query: 166 LRAEKVNEE-VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 342
++AE++++ V E +++++++ED ++N + + LE KEK E+ LN KV
Sbjct: 868 MKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEK-------ELQLLNDKV 920
Query: 343 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 522
+ + ++++ ++ + + L E Q ++ + K + + ++ +++LT +E
Sbjct: 921 ETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELT---QENG 977
Query: 523 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 702
L E + E + E ++R KS ISEL ++ K L L+ EE
Sbjct: 978 TLKEINASLNQEKMNLIQKSESFANYIDEREKS----ISELSDQYK--QEKLILLQRCEE 1031
Query: 703 KAN 711
N
Sbjct: 1032 TGN 1034
Score = 36.3 bits (80), Expect = 0.11
Identities = 46/227 (20%), Positives = 94/227 (41%), Gaps = 9/227 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKL--EKDNA-MDKADTC-EQQARDANLRAEKVNEEVRELQKKL 216
+ +A ++A + +Q KL EKDN K C E++ ++ E+ + KK
Sbjct: 1915 EHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKT 1974
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 396
+++ K K ++ E + EAEV +Q + D+ + + Q
Sbjct: 1975 TALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQ 2034
Query: 397 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLA 576
+KL ++ + + LEN+ Q + + L + + + ++D + VS+ L
Sbjct: 2035 EKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALE 2094
Query: 577 FVEDELEVAEDRVKSGDAKISELE---EELKV--VGNSLKSLEVSEE 702
E R+ S ++ +L E+L+V + K L ++E+
Sbjct: 2095 AALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEK 2141
Score = 35.9 bits (79), Expect = 0.15
Identities = 31/164 (18%), Positives = 72/164 (43%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
EQ NL E + ++++ LQ K A +++ L + ++ + +LE + + +V
Sbjct: 2553 EQNLELRNLTVE-LEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKV 2611
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
+ K +++ ++ + +++ Q++L + E NR+ L+ ++ + DQL
Sbjct: 2612 NKMTAKETELQREMHEMAQKTAELQEEL------SGEKNRLAGELQLLLEEIKSSKDQLK 2665
Query: 502 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAK 633
E L + D + K V +E+ + R+ + K
Sbjct: 2666 ELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKK 2709
>AF200415-1|AAF08305.2| 1825|Homo sapiens proliferation-related
protein P80 protein.
Length = 1825
Score = 56.8 bits (131), Expect = 7e-08
Identities = 56/200 (28%), Positives = 98/200 (49%), Gaps = 4/200 (2%)
Frame = +1
Query: 103 LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 282
LE ++ DT Q +D L + NE V++ K L Q DL LEQ +K LE
Sbjct: 1374 LEHKEVVEPKDTAIYQ-KDEALHVK--NEAVKQQDKALEQKGRDLEQKDTALEQKDKALE 1430
Query: 283 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN-NRMCKVLE 459
K+K L E + AL +K +I E+ +K+ E+ TA ++ +A + D++ + +VLE
Sbjct: 1431 PKDKDL---EEKDKALEQK-DKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLE 1486
Query: 460 NRAQQDEERMDQLTNQLKEARLLA-ED--ADGKSDEVSRKLAFVEDELEVAEDRVKSGDA 630
+ + EE+ L +++ A ED A+ K ++ + E + + E + K +
Sbjct: 1487 QKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEK 1546
Query: 631 KISELEEELKVVGNSLKSLE 690
K LE++ +G ++LE
Sbjct: 1547 KDQALEQKYWALGQKDEALE 1566
Score = 53.2 bits (122), Expect = 9e-07
Identities = 53/212 (25%), Positives = 105/212 (49%), Gaps = 6/212 (2%)
Frame = +1
Query: 106 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEE 285
EKD A+++ D ++ +D L E+ + + + K L ++DL LEQ K EE
Sbjct: 1438 EKDKALEQKDKIPEE-KDKAL--EQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEE 1494
Query: 286 KEKQLTATEAEVAALNRKVQQ--IEEDLEKSEERSGTAQQKLLEAQQSADE-NNRMCKVL 456
K+K A + +V ++ K + + E ++ E++ A ++ +AQ+ D+ + + + L
Sbjct: 1495 KDK---ALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQAL 1551
Query: 457 ENR---AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 627
E + Q +E ++Q L+E E ++ +RK +E E + ++VK+ +
Sbjct: 1552 EQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLE---EKSPEKVKAME 1608
Query: 628 AKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
K+ L E+ K +G L+ V E +A ++ E
Sbjct: 1609 EKLEALLEKTKALG--LEESLVQEGRAREQEE 1638
Score = 38.3 bits (85), Expect = 0.028
Identities = 33/149 (22%), Positives = 73/149 (48%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 249
D + ++ + + EKD A+D Q+ R +A + + V E++ + + + K
Sbjct: 1482 DRVLEQKEKIPEEKDKALD------QKVRSVEHKAPE--DTVAEMKDRDLEQTDKAPEQK 1533
Query: 250 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 429
++ ++ + EK+ Q A E + AL +K + +E++++ EE T +Q+ L +
Sbjct: 1534 HQAQEQKDKVSEKKDQ--ALEQKYWALGQKDEALEQNIQALEENHQTQEQESL----VQE 1587
Query: 430 ENNRMCKVLENRAQQDEERMDQLTNQLKE 516
+ R K+LE ++ + + M++ L E
Sbjct: 1588 DKTRKPKMLEEKSPEKVKAMEEKLEALLE 1616
>X97053-1|CAA65765.1| 566|Homo sapiens plectin protein.
Length = 566
Score = 56.4 bits (130), Expect = 1e-07
Identities = 49/204 (24%), Positives = 93/204 (45%), Gaps = 2/204 (0%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
+ NA D + EQ +A + + EE R ++ +V++ L + Q LEE
Sbjct: 196 RSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 255
Query: 289 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV--LEN 462
E+ +A V R ++ E++ + + + A QK L+A++ A K L+
Sbjct: 256 ER----LKANVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 311
Query: 463 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE 642
QQ++ +DQL + + AR AE+A+ + R+ A ++E AE R+K + ++
Sbjct: 312 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQARRQVEEAE-RLKQSAEEQAQ 370
Query: 643 LEEELKVVGNSLKSLEVSEEKANQ 714
+ + L+ E +E A +
Sbjct: 371 ARAQAQAAAEKLRK-EAEQEAARR 393
Score = 37.5 bits (83), Expect = 0.048
Identities = 53/220 (24%), Positives = 94/220 (42%), Gaps = 6/220 (2%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKA-DTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 252
++ +M+ + K A +++ T E+ + A + E E + A EE +
Sbjct: 4 VRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQL 63
Query: 253 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 432
E A + E E+ L A + R + E L K +E ++L A+ A +
Sbjct: 64 AEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL-KEKEAENERLRRL--AEDEAFQ 120
Query: 433 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 612
R+ + EER+ QL + ++ L E G ++ R+ VE+E+ +
Sbjct: 121 RRRLEEQAAQHKADIEERLAQL-RKASDSEL--ERQKGLVEDTLRQRRQVEEEILALKAS 177
Query: 613 VKSGDAKISELEEEL-KVVGN---SLKSLEVSE-EKANQR 717
+ A +ELE EL ++ N +L+S E +E E A QR
Sbjct: 178 FEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQR 217
Score = 34.7 bits (76), Expect = 0.34
Identities = 36/208 (17%), Positives = 85/208 (40%), Gaps = 2/208 (0%)
Frame = +1
Query: 106 EKDNAMDKADTCEQQARDAN-LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 282
++ A+++ + + +A LR E R+LQ ++ L + A + E
Sbjct: 247 QRKAALEEVERLKANVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE 306
Query: 283 EKEKQLTATEAEVA-ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLE 459
++ +Q E V L + + E++EE A+++ +A++ +E R+ + E
Sbjct: 307 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQARRQVEEAERLKQSAE 366
Query: 460 NRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKIS 639
+AQ + KEA A R+ + E+E + + + +
Sbjct: 367 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKA 426
Query: 640 ELEEELKVVGNSLKSLEVSEEKANQRVE 723
++E+EL + L+ + + ++ ++
Sbjct: 427 QVEQELTTLRLQLEETDHQKNLLDEELQ 454
Score = 31.1 bits (67), Expect = 4.2
Identities = 29/158 (18%), Positives = 61/158 (38%), Gaps = 1/158 (0%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
Q A M+ KK + +K + T Q + + + ++EE++ L+ + +
Sbjct: 405 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 464
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL-NRKVQQIEEDLEKSEERSGTAQQKL 405
+ +L +EE K EAE AL R + L++ E+ ++
Sbjct: 465 RQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 524
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA 519
+A E R+ ++ E Q +++ + +A
Sbjct: 525 ARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQA 562
>X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin heavy
chain protein.
Length = 881
Score = 56.4 bits (130), Expect = 1e-07
Identities = 55/249 (22%), Positives = 118/249 (47%), Gaps = 16/249 (6%)
Frame = +1
Query: 25 VFNSTGP*QQKAATMDAIKKKMQ-----AMKLEKDNAMDKADTCEQQARDANLRAEKVNE 189
+F + ++KA +++A ++Q A + K ++K + E+ A + R + +
Sbjct: 580 IFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR-NALQD 638
Query: 190 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 369
E R L+ ++AQ+EE+L + +E + + + +Q E+A Q+ E ++
Sbjct: 639 EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESSRQQ 698
Query: 370 SEERSGTAQQKLLEAQQSADENNRMC-KVLENRAQQDEERMDQLTNQLKEARLLAEDADG 546
E ++ + KL E + + + LE + Q EE+++Q + + A + D
Sbjct: 699 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 758
Query: 547 KSDEVSRKLAFVEDELEVAE---DRVKSGDAKISEL-------EEELKVVGNSLKSLEVS 696
K E+ L VEDE ++AE ++ + G+A++ +L EEE + + + + L+
Sbjct: 759 KLKEI---LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 815
Query: 697 EEKANQRVE 723
++A + E
Sbjct: 816 LDEATESNE 824
Score = 54.8 bits (126), Expect = 3e-07
Identities = 38/200 (19%), Positives = 98/200 (49%), Gaps = 5/200 (2%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E ++ +
Sbjct: 643 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNES---SRQQ 698
Query: 256 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 699 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 758
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 759 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 818
Query: 601 AEDRVKSGDAKISELEEELK 660
A + ++ +++ L+ +L+
Sbjct: 819 ATESNEAMGREVNALKSKLR 838
Score = 52.4 bits (120), Expect = 2e-06
Identities = 41/223 (18%), Positives = 103/223 (46%), Gaps = 19/223 (8%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 216
+++ A A KKK++ ++L+ D+A+ + +Q R + + E+ + +
Sbjct: 518 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 577
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS-------E 375
++ N+ K + DL + ++ L A E + + +++ E+L S +
Sbjct: 578 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ 637
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
+ + ++ + ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 638 DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESSRQ 697
Query: 556 EVSRKLAFVEDELEVAEDRVKSG--------DAKISELEEELK 660
++ R+ + +L E VKS +AKI++LEE+++
Sbjct: 698 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVE 740
Score = 50.8 bits (116), Expect = 5e-06
Identities = 37/217 (17%), Positives = 92/217 (42%), Gaps = 1/217 (0%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++++ +++ + D M+ E+ N++ +++++ + +EE + +
Sbjct: 250 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 309
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADE 432
+E + EEK E L +++ + DL+ + ++K + Q A+E
Sbjct: 310 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 369
Query: 433 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 612
N K + R + + E ++ T L AR L E + K +E+ R ++ E+E
Sbjct: 370 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSS 428
Query: 613 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ ELE+ + + ++ ++ E+ ++
Sbjct: 429 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQ 465
Score = 48.0 bits (109), Expect = 3e-05
Identities = 39/186 (20%), Positives = 91/186 (48%), Gaps = 3/186 (1%)
Frame = +1
Query: 172 AEKVN--EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 345
A+K N +++REL+ ++ ++EDL E+A ++ EK+K+ E E AL +++
Sbjct: 13 AQKNNALKKIRELEGHISDLQEDL-----DSERAARNKAEKQKRDLGEELE--ALKTELE 65
Query: 346 QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV-LENRAQQDEERMDQLTNQLKEAR 522
+ +E +Q++ +++ DE R + ++ Q+ + +++LT QL++ +
Sbjct: 66 DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFK 125
Query: 523 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 702
+ D + ++ A + EL V + + K +LE +++ + + E +
Sbjct: 126 RAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 185
Query: 703 KANQRV 720
+ N +V
Sbjct: 186 ELNDKV 191
Score = 47.6 bits (108), Expect = 4e-05
Identities = 45/206 (21%), Positives = 88/206 (42%), Gaps = 1/206 (0%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
K D A T E + R +K E + + ++ A + L KN+L+Q DL
Sbjct: 286 KKKLQDFASTVEA-LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 344
Query: 289 EKQLTATEAEVAALNRKVQQI-EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 465
+ + RK Q+ E+ S + + + EA++ + + + LE
Sbjct: 345 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 404
Query: 466 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
+ EE + TN++ +A + ED D+V + + +E E +++ ++ EL
Sbjct: 405 LEAKEEL--ERTNKMLKAEM--EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 460
Query: 646 EEELKVVGNSLKSLEVSEEKANQRVE 723
E+EL+ ++ LEV+ + + E
Sbjct: 461 EDELQATEDAKLRLEVNMQALKGQFE 486
Score = 45.6 bits (103), Expect = 2e-04
Identities = 47/223 (21%), Positives = 102/223 (45%), Gaps = 9/223 (4%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 222
++ A +A +K+ +A+ L + + A++ + E+ + E + ++ K + +
Sbjct: 379 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 438
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 390
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E++
Sbjct: 439 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 498
Query: 391 AQQKL---LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 561
+++L L ++ E+ R + L A++ +L LK+ L A+ A +E
Sbjct: 499 KRRQLQRQLHEYETELEDERKQRALAAAAKK------KLEGDLKDLELQADSAIKGREEA 552
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
++L ++ +++ + ++ A E+ K KSLE
Sbjct: 553 IKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 595
Score = 38.7 bits (86), Expect = 0.021
Identities = 33/129 (25%), Positives = 65/129 (50%), Gaps = 1/129 (0%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++K A ++K+K + +K D+ EQ +AEK N V++L+++L + E
Sbjct: 744 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE----QAEKGNARVKQLKRQLEEAE 799
Query: 229 ED-LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
E+ +N N+ + ++L+E + A EV AL K+++ E RSG +++
Sbjct: 800 EESQRINANR-RKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSG--GRRV 856
Query: 406 LEAQQSADE 432
+E ++E
Sbjct: 857 IENADGSEE 865
>U63610-1|AAB05428.1| 4574|Homo sapiens plectin protein.
Length = 4574
Score = 56.4 bits (130), Expect = 1e-07
Identities = 49/204 (24%), Positives = 93/204 (45%), Gaps = 2/204 (0%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
+ NA D + EQ +A + + EE R ++ +V++ L + Q LEE
Sbjct: 1979 RSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 2038
Query: 289 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV--LEN 462
E+ +A V R ++ E++ + + + A QK L+A++ A K L+
Sbjct: 2039 ER----LKANVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 2094
Query: 463 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE 642
QQ++ +DQL + + AR AE+A+ + R+ A ++E AE R+K + ++
Sbjct: 2095 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQARRQVEEAE-RLKQSAEEQAQ 2153
Query: 643 LEEELKVVGNSLKSLEVSEEKANQ 714
+ + L+ E +E A +
Sbjct: 2154 ARAQAQAAAEKLRK-EAEQEAARR 2176
Score = 49.2 bits (112), Expect = 1e-05
Identities = 48/229 (20%), Positives = 110/229 (48%), Gaps = 10/229 (4%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNA-MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE---E 231
T++A +++ M E + + A+ QAR A A++ ++ E+ +KL + E +
Sbjct: 2394 TLEAERQRQLEMSAEAERLKLRVAEMSRAQAR-AEEDAQRFRKQAEEIGEKLHRTELATQ 2452
Query: 232 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTAQQKLL 408
+ + LE + + ++L AE+ K+QQ + L+ KSEE Q++LL
Sbjct: 2453 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLL 2512
Query: 409 EAQQSADEN--NRMCKVLENRA--QQDEERMDQL-TNQLKEARLLAEDADGKSDEVSRKL 573
+ Q+ ++ + +L+ +Q++ +++QL +++ +A+ L E+ + ++ ++
Sbjct: 2513 QETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQER 2572
Query: 574 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ +E A R + + +EEL+ + + E + NQR+
Sbjct: 2573 QRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRL 2621
Score = 48.0 bits (109), Expect = 3e-05
Identities = 54/223 (24%), Positives = 104/223 (46%), Gaps = 12/223 (5%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKK---LAQVEEDLILNKN 252
++ + +++ + A A+ E Q++ A+ AEK + R LQ++ +AQ+ E+
Sbjct: 1585 ERARQVQVALETAQRSAEA-ELQSKRASF-AEKTAQLERSLQEEHVAVAQLREEAERRAQ 1642
Query: 253 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 432
+ +A + EE E++L + + R Q EE ++ A+++ EA++ A
Sbjct: 1643 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARR 1702
Query: 433 NNRMCK-VLENR--AQQDEERMDQLTNQLKEARLLAED------ADGKSDEVSRKLAFVE 585
+ + + R A+Q+ E+ QL + RL AE A+ + E R+L +E
Sbjct: 1703 RGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQL--LE 1760
Query: 586 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
+EL + + K ELE EL V ++ L S+ +A +
Sbjct: 1761 EELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEE 1803
Score = 44.8 bits (101), Expect = 3e-04
Identities = 47/206 (22%), Positives = 81/206 (39%), Gaps = 3/206 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN-EEVRELQKKL--A 219
Q + +K + +A + EK A+ + QA +A R + E R++Q L A
Sbjct: 1539 QAEVELASRVKAETEAAR-EKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETA 1597
Query: 220 QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 399
Q + L + A K + E+ L VA L + ++ + ++E A++
Sbjct: 1598 QRSAEAELQSKRASFAEKTAQ-LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAER 1656
Query: 400 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 579
+L Q A+E R+ E AQQ + Q +EA A ++ R+
Sbjct: 1657 ELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQREL 1716
Query: 580 VEDELEVAEDRVKSGDAKISELEEEL 657
E ELE + + E+EL
Sbjct: 1717 AEQELEKQRQLAEGTAQQRLAAEQEL 1742
Score = 39.9 bits (89), Expect = 0.009
Identities = 55/229 (24%), Positives = 98/229 (42%), Gaps = 6/229 (2%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKA-DTCEQQARDANLRAEKVNEEVRELQKKLAQV 225
Q+ A + ++ +M+ + K A +++ T E+ + A + E E + A
Sbjct: 1778 QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALA 1837
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
EE + E A + E E+ L A + R + E L K +E ++L
Sbjct: 1838 EEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL-KEKEAENERLRRL 1896
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
A+ A + R+ + EER+ QL + ++ L E G ++ R+ VE
Sbjct: 1897 --AEDEAFQRRRLEEQAAQHKADIEERLAQL-RKASDSEL--ERQKGLVEDTLRQRRQVE 1951
Query: 586 DELEVAEDRVKSGDAKISELEEEL-KVVGN---SLKSLEVSE-EKANQR 717
+E+ + + A +ELE EL ++ N +L+S E +E E A QR
Sbjct: 1952 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQR 2000
Score = 37.5 bits (83), Expect = 0.048
Identities = 33/147 (22%), Positives = 71/147 (48%), Gaps = 5/147 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQ---ARDANLRAEKVNEEVRELQKKLA 219
QQ+A + ++MQ ++ E+ + + +Q +D+ L+ E+ E+ + KL
Sbjct: 2490 QQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQEKA---KLE 2544
Query: 220 QVEEDLILNKNKL-EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTA 393
Q+ +D + +L E+ + ++ E++ A + R+ + EE + K EE
Sbjct: 2545 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2604
Query: 394 QQKLLEAQQSADENNRMCKVLENRAQQ 474
QQ+ + + A+EN R+ + L+ +Q
Sbjct: 2605 QQRRQQEELLAEENQRLREQLQLLEEQ 2631
Score = 37.1 bits (82), Expect = 0.064
Identities = 30/131 (22%), Positives = 63/131 (48%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+ +A + +K ++ E+ +KA EQ +D +A+++ EE + Q+++ Q
Sbjct: 2514 ETQALQQSFLSEKDSLLQRERFIEQEKAKL-EQLFQDEVAKAQQLREEQQRQQQQMEQER 2572
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
+ L+ + +E+A + E E+ + + E+ QQ+E+ + EE Q+L
Sbjct: 2573 QRLVAS---MEEARRRQHEAEEGVRRKQEEL-------QQLEQQRRQQEELLAEENQRLR 2622
Query: 409 EAQQSADENNR 441
E Q +E +R
Sbjct: 2623 EQLQLLEEQHR 2633
Score = 36.7 bits (81), Expect = 0.084
Identities = 46/214 (21%), Positives = 91/214 (42%), Gaps = 12/214 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
Q A M+ KK + +K + T Q + + + ++EE++ L+ + +
Sbjct: 2188 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2247
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL-----NRKVQQIEEDLEKSEE----- 378
+ +L +EE K EAE AL + + ++E+ EK ++
Sbjct: 2248 RQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2307
Query: 379 -RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK-EARLLAEDADGKS 552
R A Q+ +Q A+E+ + L + +++ + Q +LK EA LL + + +
Sbjct: 2308 ARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LA 2366
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 654
E +R+L ED+ ++A+ + LE E
Sbjct: 2367 QEQARRLQ--EDKEQMAQQLAEETQGFQRTLEAE 2398
Score = 34.7 bits (76), Expect = 0.34
Identities = 36/208 (17%), Positives = 85/208 (40%), Gaps = 2/208 (0%)
Frame = +1
Query: 106 EKDNAMDKADTCEQQARDAN-LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 282
++ A+++ + + +A LR E R+LQ ++ L + A + E
Sbjct: 2030 QRKAALEEVERLKANVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE 2089
Query: 283 EKEKQLTATEAEVA-ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLE 459
++ +Q E V L + + E++EE A+++ +A++ +E R+ + E
Sbjct: 2090 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQARRQVEEAERLKQSAE 2149
Query: 460 NRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKIS 639
+AQ + KEA A R+ + E+E + + + +
Sbjct: 2150 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKA 2209
Query: 640 ELEEELKVVGNSLKSLEVSEEKANQRVE 723
++E+EL + L+ + + ++ ++
Sbjct: 2210 QVEQELTTLRLQLEETDHQKNLLDEELQ 2237
>U53204-1|AAB05427.1| 4574|Homo sapiens plectin protein.
Length = 4574
Score = 56.4 bits (130), Expect = 1e-07
Identities = 49/204 (24%), Positives = 93/204 (45%), Gaps = 2/204 (0%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
+ NA D + EQ +A + + EE R ++ +V++ L + Q LEE
Sbjct: 1979 RSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 2038
Query: 289 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV--LEN 462
E+ +A V R ++ E++ + + + A QK L+A++ A K L+
Sbjct: 2039 ER----LKANVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 2094
Query: 463 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE 642
QQ++ +DQL + + AR AE+A+ + R+ A ++E AE R+K + ++
Sbjct: 2095 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQARRQVEEAE-RLKQSAEEQAQ 2153
Query: 643 LEEELKVVGNSLKSLEVSEEKANQ 714
+ + L+ E +E A +
Sbjct: 2154 ARAQAQAAAEKLRK-EAEQEAARR 2176
Score = 49.2 bits (112), Expect = 1e-05
Identities = 48/229 (20%), Positives = 110/229 (48%), Gaps = 10/229 (4%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNA-MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE---E 231
T++A +++ M E + + A+ QAR A A++ ++ E+ +KL + E +
Sbjct: 2394 TLEAERQRQLEMSAEAERLKLRVAEMSRAQAR-AEEDAQRFRKQAEEIGEKLHRTELATQ 2452
Query: 232 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTAQQKLL 408
+ + LE + + ++L AE+ K+QQ + L+ KSEE Q++LL
Sbjct: 2453 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLL 2512
Query: 409 EAQQSADEN--NRMCKVLENRA--QQDEERMDQL-TNQLKEARLLAEDADGKSDEVSRKL 573
+ Q+ ++ + +L+ +Q++ +++QL +++ +A+ L E+ + ++ ++
Sbjct: 2513 QETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQER 2572
Query: 574 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ +E A R + + +EEL+ + + E + NQR+
Sbjct: 2573 QRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRL 2621
Score = 48.0 bits (109), Expect = 3e-05
Identities = 54/223 (24%), Positives = 104/223 (46%), Gaps = 12/223 (5%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKK---LAQVEEDLILNKN 252
++ + +++ + A A+ E Q++ A+ AEK + R LQ++ +AQ+ E+
Sbjct: 1585 ERARQVQVALETAQRSAEA-ELQSKRASF-AEKTAQLERSLQEEHVAVAQLREEAERRAQ 1642
Query: 253 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 432
+ +A + EE E++L + + R Q EE ++ A+++ EA++ A
Sbjct: 1643 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARR 1702
Query: 433 NNRMCK-VLENR--AQQDEERMDQLTNQLKEARLLAED------ADGKSDEVSRKLAFVE 585
+ + + R A+Q+ E+ QL + RL AE A+ + E R+L +E
Sbjct: 1703 RGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQL--LE 1760
Query: 586 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
+EL + + K ELE EL V ++ L S+ +A +
Sbjct: 1761 EELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEE 1803
Score = 44.8 bits (101), Expect = 3e-04
Identities = 47/206 (22%), Positives = 81/206 (39%), Gaps = 3/206 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN-EEVRELQKKL--A 219
Q + +K + +A + EK A+ + QA +A R + E R++Q L A
Sbjct: 1539 QAEVELASRVKAETEAAR-EKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETA 1597
Query: 220 QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 399
Q + L + A K + E+ L VA L + ++ + ++E A++
Sbjct: 1598 QRSAEAELQSKRASFAEKTAQ-LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAER 1656
Query: 400 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 579
+L Q A+E R+ E AQQ + Q +EA A ++ R+
Sbjct: 1657 ELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQREL 1716
Query: 580 VEDELEVAEDRVKSGDAKISELEEEL 657
E ELE + + E+EL
Sbjct: 1717 AEQELEKQRQLAEGTAQQRLAAEQEL 1742
Score = 39.9 bits (89), Expect = 0.009
Identities = 55/229 (24%), Positives = 98/229 (42%), Gaps = 6/229 (2%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKA-DTCEQQARDANLRAEKVNEEVRELQKKLAQV 225
Q+ A + ++ +M+ + K A +++ T E+ + A + E E + A
Sbjct: 1778 QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALA 1837
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
EE + E A + E E+ L A + R + E L K +E ++L
Sbjct: 1838 EEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL-KEKEAENERLRRL 1896
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
A+ A + R+ + EER+ QL + ++ L E G ++ R+ VE
Sbjct: 1897 --AEDEAFQRRRLEEQAAQHKADIEERLAQL-RKASDSEL--ERQKGLVEDTLRQRRQVE 1951
Query: 586 DELEVAEDRVKSGDAKISELEEEL-KVVGN---SLKSLEVSE-EKANQR 717
+E+ + + A +ELE EL ++ N +L+S E +E E A QR
Sbjct: 1952 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQR 2000
Score = 37.5 bits (83), Expect = 0.048
Identities = 33/147 (22%), Positives = 71/147 (48%), Gaps = 5/147 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQ---ARDANLRAEKVNEEVRELQKKLA 219
QQ+A + ++MQ ++ E+ + + +Q +D+ L+ E+ E+ + KL
Sbjct: 2490 QQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQEKA---KLE 2544
Query: 220 QVEEDLILNKNKL-EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTA 393
Q+ +D + +L E+ + ++ E++ A + R+ + EE + K EE
Sbjct: 2545 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2604
Query: 394 QQKLLEAQQSADENNRMCKVLENRAQQ 474
QQ+ + + A+EN R+ + L+ +Q
Sbjct: 2605 QQRRQQEELLAEENQRLREQLQLLEEQ 2631
Score = 37.1 bits (82), Expect = 0.064
Identities = 30/131 (22%), Positives = 63/131 (48%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+ +A + +K ++ E+ +KA EQ +D +A+++ EE + Q+++ Q
Sbjct: 2514 ETQALQQSFLSEKDSLLQRERFIEQEKAKL-EQLFQDEVAKAQQLREEQQRQQQQMEQER 2572
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
+ L+ + +E+A + E E+ + + E+ QQ+E+ + EE Q+L
Sbjct: 2573 QRLVAS---MEEARRRQHEAEEGVRRKQEEL-------QQLEQQRRQQEELLAEENQRLR 2622
Query: 409 EAQQSADENNR 441
E Q +E +R
Sbjct: 2623 EQLQLLEEQHR 2633
Score = 36.7 bits (81), Expect = 0.084
Identities = 46/214 (21%), Positives = 91/214 (42%), Gaps = 12/214 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
Q A M+ KK + +K + T Q + + + ++EE++ L+ + +
Sbjct: 2188 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2247
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL-----NRKVQQIEEDLEKSEE----- 378
+ +L +EE K EAE AL + + ++E+ EK ++
Sbjct: 2248 RQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2307
Query: 379 -RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK-EARLLAEDADGKS 552
R A Q+ +Q A+E+ + L + +++ + Q +LK EA LL + + +
Sbjct: 2308 ARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LA 2366
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 654
E +R+L ED+ ++A+ + LE E
Sbjct: 2367 QEQARRLQ--EDKEQMAQQLAEETQGFQRTLEAE 2398
Score = 34.7 bits (76), Expect = 0.34
Identities = 36/208 (17%), Positives = 85/208 (40%), Gaps = 2/208 (0%)
Frame = +1
Query: 106 EKDNAMDKADTCEQQARDAN-LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 282
++ A+++ + + +A LR E R+LQ ++ L + A + E
Sbjct: 2030 QRKAALEEVERLKANVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE 2089
Query: 283 EKEKQLTATEAEVA-ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLE 459
++ +Q E V L + + E++EE A+++ +A++ +E R+ + E
Sbjct: 2090 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQARRQVEEAERLKQSAE 2149
Query: 460 NRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKIS 639
+AQ + KEA A R+ + E+E + + + +
Sbjct: 2150 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKA 2209
Query: 640 ELEEELKVVGNSLKSLEVSEEKANQRVE 723
++E+EL + L+ + + ++ ++
Sbjct: 2210 QVEQELTTLRLQLEETDHQKNLLDEELQ 2237
>BC112391-1|AAI12392.1| 957|Homo sapiens ELKS/RAB6-interacting/CAST
family member 2 protein.
Length = 957
Score = 56.4 bits (130), Expect = 1e-07
Identities = 49/224 (21%), Positives = 104/224 (46%), Gaps = 3/224 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+Q+AA + ++ EK++ ++K +Q +D + E+R+++ L E
Sbjct: 482 EQRAAILQTEVDALRLRLEEKESFLNKKT---KQLQDLTEEKGTLAGEIRDMKDMLEVKE 538
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
+ + + K+E + L +K+KQLT L +V+ ++ D ++ T ++ L
Sbjct: 539 RKINVLQKKIENLQEQLRDKDKQLT-------NLKDRVKSLQTDSSNTDTALATLEEALS 591
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
E ++ + ++ E R + D ER++++ + KE + L E + E++ K + + D
Sbjct: 592 EKERIIE------RLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLID 645
Query: 589 ELEVAEDRVKSG---DAKISELEEELKVVGNSLKSLEVSEEKAN 711
E A +G D+K+ LE ++ LE +KA+
Sbjct: 646 LKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAH 689
Score = 44.0 bits (99), Expect = 6e-04
Identities = 56/236 (23%), Positives = 107/236 (45%), Gaps = 11/236 (4%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-VRELQKKLAQV 225
+ K + +K ++++++ + N T E+ + E++ E+ R+ +++L ++
Sbjct: 556 RDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEI 615
Query: 226 EEDLILNKNKLEQANK---DLEEKEKQLT-----ATEAEVAALNR--KVQQIEEDLEKSE 375
E NK+ E+ N +L EKE L A+ A L R K++ +E +E+ +
Sbjct: 616 ESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKK 675
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
E LEAQ N +E+ ++ + E DQ+ KEA ++
Sbjct: 676 EECSK-----LEAQLKKAHN------IEDDSRMNPEFADQIKQLDKEASYYRDECGKAQA 724
Query: 556 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
EV R L +++ E+ D KI+EL E L + ++ +V+ K NQ++E
Sbjct: 725 EVDRLLEILKE----VENEKNDKDKKIAEL-ESLTLRHMKDQNKKVANLKHNQQLE 775
Score = 31.5 bits (68), Expect = 3.2
Identities = 32/155 (20%), Positives = 71/155 (45%), Gaps = 1/155 (0%)
Frame = +1
Query: 193 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 372
+++ KK+A ++ + L K K Q +++ +E + + +++++ LEK+
Sbjct: 758 MKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHL-----QIEELMNALEKT 812
Query: 373 EERSGTAQQKLLEAQQS-ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 549
+ + +L QQS A++ + + R +Q EE ++ L A + +DA+
Sbjct: 813 RQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALL-AAISEKDANIA 871
Query: 550 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 654
E+S E +A R K D + +L+++
Sbjct: 872 LLELSASKKKKTQEEVMALKREK--DRLVHQLKQQ 904
>BC111550-1|AAI11551.1| 957|Homo sapiens ERC2 protein protein.
Length = 957
Score = 56.4 bits (130), Expect = 1e-07
Identities = 49/224 (21%), Positives = 104/224 (46%), Gaps = 3/224 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+Q+AA + ++ EK++ ++K +Q +D + E+R+++ L E
Sbjct: 482 EQRAAILQTEVDALRLRLEEKESFLNKKT---KQLQDLTEEKGTLAGEIRDMKDMLEVKE 538
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
+ + + K+E + L +K+KQLT L +V+ ++ D ++ T ++ L
Sbjct: 539 RKINVLQKKIENLQEQLRDKDKQLT-------NLKDRVKSLQTDSSNTDTALATLEEALS 591
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
E ++ + ++ E R + D ER++++ + KE + L E + E++ K + + D
Sbjct: 592 EKERIIE------RLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLID 645
Query: 589 ELEVAEDRVKSG---DAKISELEEELKVVGNSLKSLEVSEEKAN 711
E A +G D+K+ LE ++ LE +KA+
Sbjct: 646 LKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAH 689
Score = 44.0 bits (99), Expect = 6e-04
Identities = 56/236 (23%), Positives = 107/236 (45%), Gaps = 11/236 (4%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-VRELQKKLAQV 225
+ K + +K ++++++ + N T E+ + E++ E+ R+ +++L ++
Sbjct: 556 RDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEI 615
Query: 226 EEDLILNKNKLEQANK---DLEEKEKQLT-----ATEAEVAALNR--KVQQIEEDLEKSE 375
E NK+ E+ N +L EKE L A+ A L R K++ +E +E+ +
Sbjct: 616 ESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKK 675
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
E LEAQ N +E+ ++ + E DQ+ KEA ++
Sbjct: 676 EECSK-----LEAQLKKAHN------IEDDSRMNPEFADQIKQLDKEASYYRDECGKAQA 724
Query: 556 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
EV R L +++ E+ D KI+EL E L + ++ +V+ K NQ++E
Sbjct: 725 EVDRLLEILKE----VENEKNDKDKKIAEL-ESLTLRHMKDQNKKVANLKHNQQLE 775
Score = 31.5 bits (68), Expect = 3.2
Identities = 32/155 (20%), Positives = 71/155 (45%), Gaps = 1/155 (0%)
Frame = +1
Query: 193 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 372
+++ KK+A ++ + L K K Q +++ +E + + +++++ LEK+
Sbjct: 758 MKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHL-----QIEELMNALEKT 812
Query: 373 EERSGTAQQKLLEAQQS-ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 549
+ + +L QQS A++ + + R +Q EE ++ L A + +DA+
Sbjct: 813 RQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALL-AAISEKDANIA 871
Query: 550 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 654
E+S E +A R K D + +L+++
Sbjct: 872 LLELSASKKKKTQEEVMALKREK--DRLVHQLKQQ 904
>BC101520-1|AAI01521.1| 1194|Homo sapiens protein tyrosine
phosphatase, receptor type, f polypeptide (PTPRF),
interacting protein.
Length = 1194
Score = 56.4 bits (130), Expect = 1e-07
Identities = 48/195 (24%), Positives = 93/195 (47%), Gaps = 10/195 (5%)
Frame = +1
Query: 157 DANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR 336
D+N R ++ E + + ++ Q+ E L + ++ Q ++L ++L E + L R
Sbjct: 230 DSNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKLQR 289
Query: 337 KVQQIEEDLEKSEERSGTAQQKLLEAQQSA----DENNRMCKVL---ENRAQQDEERMDQ 495
+++ E EER T +++ L AQ+ A D N+++ L E+ +Q EE+ Q
Sbjct: 290 DLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQ 349
Query: 496 LTNQLKEARLLAEDADGKSD---EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 666
L L +A+ + K++ E+ +LA L AE+R + + ++ +LE +L+
Sbjct: 350 LAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEK 409
Query: 667 GNSLKSLEVSEEKAN 711
L+ EK N
Sbjct: 410 NQELQRAR-QREKMN 423
Score = 46.8 bits (106), Expect = 8e-05
Identities = 34/152 (22%), Positives = 71/152 (46%)
Frame = +1
Query: 265 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 444
+N+ E E+ L AEV L ++ + + + EE GTA ++L +A+++ + R
Sbjct: 231 SNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKLQRD 290
Query: 445 CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 624
K + + EER+ L + A+ A +D++ +LA E +E++ +
Sbjct: 291 LKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQL 350
Query: 625 DAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ + +++L+ ++L E + QRV
Sbjct: 351 AEWLDDAKQKLQQTLQKAETLPEIEAQLAQRV 382
Score = 40.7 bits (91), Expect = 0.005
Identities = 37/183 (20%), Positives = 82/183 (44%), Gaps = 3/183 (1%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++K+ + + E + D D E + + E+ R+L + L ++ L K
Sbjct: 308 LEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQLAEWLDDAKQKLQQTLQK 367
Query: 256 LE---QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
E + L ++ L E +++Q+E LE+ + A+Q+ + +
Sbjct: 368 AETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEKNQELQRARQR---EKMND 424
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
D N R+ + ++ + ER+ QL LKE E+ + S+E++ + ++DEL + +
Sbjct: 425 DHNKRLSETVDKLLSESNERL-QL--HLKERMGALEEKNSLSEEIA-NMKKLQDELLLNK 480
Query: 607 DRV 615
+++
Sbjct: 481 EQL 483
>BC101518-1|AAI01519.1| 1194|Homo sapiens protein tyrosine
phosphatase, receptor type, f polypeptide (PTPRF),
interacting protein.
Length = 1194
Score = 56.4 bits (130), Expect = 1e-07
Identities = 48/195 (24%), Positives = 93/195 (47%), Gaps = 10/195 (5%)
Frame = +1
Query: 157 DANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR 336
D+N R ++ E + + ++ Q+ E L + ++ Q ++L ++L E + L R
Sbjct: 230 DSNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKLQR 289
Query: 337 KVQQIEEDLEKSEERSGTAQQKLLEAQQSA----DENNRMCKVL---ENRAQQDEERMDQ 495
+++ E EER T +++ L AQ+ A D N+++ L E+ +Q EE+ Q
Sbjct: 290 DLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQ 349
Query: 496 LTNQLKEARLLAEDADGKSD---EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 666
L L +A+ + K++ E+ +LA L AE+R + + ++ +LE +L+
Sbjct: 350 LAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEK 409
Query: 667 GNSLKSLEVSEEKAN 711
L+ EK N
Sbjct: 410 NQELQRAR-QREKMN 423
Score = 46.8 bits (106), Expect = 8e-05
Identities = 34/152 (22%), Positives = 71/152 (46%)
Frame = +1
Query: 265 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 444
+N+ E E+ L AEV L ++ + + + EE GTA ++L +A+++ + R
Sbjct: 231 SNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKLQRD 290
Query: 445 CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 624
K + + EER+ L + A+ A +D++ +LA E +E++ +
Sbjct: 291 LKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQL 350
Query: 625 DAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ + +++L+ ++L E + QRV
Sbjct: 351 AEWLDDAKQKLQQTLQKAETLPEIEAQLAQRV 382
Score = 40.7 bits (91), Expect = 0.005
Identities = 37/183 (20%), Positives = 82/183 (44%), Gaps = 3/183 (1%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++K+ + + E + D D E + + E+ R+L + L ++ L K
Sbjct: 308 LEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQLAEWLDDAKQKLQQTLQK 367
Query: 256 LE---QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
E + L ++ L E +++Q+E LE+ + A+Q+ + +
Sbjct: 368 AETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEKNQELQRARQR---EKMND 424
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
D N R+ + ++ + ER+ QL LKE E+ + S+E++ + ++DEL + +
Sbjct: 425 DHNKRLSETVDKLLSESNERL-QL--HLKERMGALEEKNSLSEEIA-NMKKLQDELLLNK 480
Query: 607 DRV 615
+++
Sbjct: 481 EQL 483
>AB209115-1|BAD92352.1| 1065|Homo sapiens restin isoform a variant
protein.
Length = 1065
Score = 56.4 bits (130), Expect = 1e-07
Identities = 46/234 (19%), Positives = 112/234 (47%), Gaps = 12/234 (5%)
Frame = +1
Query: 58 AATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANL--RAEKVNE-EVRELQK-KLAQV 225
A M+A++ K+ + EK+N+++ + +A D +L + +N+ + E++K K A+
Sbjct: 429 AKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKKEKFAEA 488
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG---TAQ 396
E+ + + +++ L +KE+Q +++ L + +E + +ER A+
Sbjct: 489 SEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAK 548
Query: 397 QKL----LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 564
+KL E + + +N+ + + + E +++L +L +A A ++++
Sbjct: 549 EKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMT 608
Query: 565 RKLAFVEDE-LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
K + E + E+ K + K+S+LE++++ N + L+ E+A +
Sbjct: 609 VKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETK 662
Score = 50.4 bits (115), Expect = 6e-06
Identities = 68/239 (28%), Positives = 104/239 (43%), Gaps = 20/239 (8%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR--------EL 204
QQ+AA +KK KL + K +T Q ++ R E+ E + L
Sbjct: 615 QQEAAKKHEEEKKELERKLS--DLEKKMETSHNQCQELKARYERATSETKTKHEEILQNL 672
Query: 205 QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS 384
QK L E+ L + + ++LEE KQ A +A+ A QI E + K E++
Sbjct: 673 QKTLLDTEDKLKGAREENSGLLQELEELRKQ--AEKAKAAQTAEDAMQIMEQMTK--EKT 728
Query: 385 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEE---RMDQLT--NQ-----LKEARLLAE 534
T Q +A N + + EN + EE + LT NQ KE L +
Sbjct: 729 ETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQ 788
Query: 535 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKIS--ELEEELKVVGNSLKSLEVSEEK 705
A KS ++S A E+ +++AE+ +S D S +LEEE V+ N L ++ E K
Sbjct: 789 AAAQKSQQLS---ALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESK 844
Score = 36.3 bits (80), Expect = 0.11
Identities = 49/210 (23%), Positives = 88/210 (41%)
Frame = +1
Query: 28 FNSTGP*QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQ 207
F ST P + KA + + A L++ + + A + R + + E
Sbjct: 34 FPSTTPAKAKANAVRRVMATTSA-SLKRSPSASSLSSMSSVASSVSSRPSRTGL-LTETS 91
Query: 208 KKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 387
+ A+ + L++ + +E+ + AEVA V +IE++L + R G
Sbjct: 92 SRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALA--RDG 149
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
Q +LE + D+ M + D E+++ L NQL+E + ED + +E S
Sbjct: 150 H-DQHVLELEAKMDQLRTMVEAA------DREKVE-LLNQLEEEKRKVEDLQFRVEEES- 200
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEEL 657
+ +LE + K A+I ELE+ L
Sbjct: 201 ---ITKGDLET---QTKLEHARIKELEQSL 224
Score = 31.1 bits (67), Expect = 4.2
Identities = 41/195 (21%), Positives = 87/195 (44%), Gaps = 10/195 (5%)
Frame = +1
Query: 169 RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQ 348
R E +E++ L ++ ++ K+KLE ANK E + ++++ QQ
Sbjct: 320 REETHQKEIKALYTATEKLSKENESLKSKLEHANK---ENSDVIALWKSKLETAIASHQQ 376
Query: 349 IEEDLEKSEERS-GTAQQKLLEAQQSADENNRMCK-VLEN-RAQQDEERMDQLTN-QLKE 516
E+L+ S + GT + E + ++ + +EN + QQD ER +
Sbjct: 377 AMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALR 436
Query: 517 ARLL--AEDADGKSDEVSRKLAFVED----ELEVAEDRVKSGDAKISELEEELKVVGNSL 678
A+L+ ++ + + + KL ED E+E ++++ + K + E + +
Sbjct: 437 AKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKKEKFAEASEEAVSVQ 496
Query: 679 KSLEVSEEKANQRVE 723
+S++ + K +Q+ E
Sbjct: 497 RSMQETVNKLHQKEE 511
>AB014554-1|BAA31629.2| 1267|Homo sapiens KIAA0654 protein protein.
Length = 1267
Score = 56.4 bits (130), Expect = 1e-07
Identities = 48/195 (24%), Positives = 93/195 (47%), Gaps = 10/195 (5%)
Frame = +1
Query: 157 DANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR 336
D+N R ++ E + + ++ Q+ E L + ++ Q ++L ++L E + L R
Sbjct: 303 DSNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKLQR 362
Query: 337 KVQQIEEDLEKSEERSGTAQQKLLEAQQSA----DENNRMCKVL---ENRAQQDEERMDQ 495
+++ E EER T +++ L AQ+ A D N+++ L E+ +Q EE+ Q
Sbjct: 363 DLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQ 422
Query: 496 LTNQLKEARLLAEDADGKSD---EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 666
L L +A+ + K++ E+ +LA L AE+R + + ++ +LE +L+
Sbjct: 423 LAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEK 482
Query: 667 GNSLKSLEVSEEKAN 711
L+ EK N
Sbjct: 483 NQELQRAR-QREKMN 496
Score = 46.8 bits (106), Expect = 8e-05
Identities = 34/152 (22%), Positives = 71/152 (46%)
Frame = +1
Query: 265 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 444
+N+ E E+ L AEV L ++ + + + EE GTA ++L +A+++ + R
Sbjct: 304 SNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKLQRD 363
Query: 445 CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 624
K + + EER+ L + A+ A +D++ +LA E +E++ +
Sbjct: 364 LKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQL 423
Query: 625 DAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ + +++L+ ++L E + QRV
Sbjct: 424 AEWLDDAKQKLQQTLQKAETLPEIEAQLAQRV 455
Score = 40.7 bits (91), Expect = 0.005
Identities = 37/183 (20%), Positives = 82/183 (44%), Gaps = 3/183 (1%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++K+ + + E + D D E + + E+ R+L + L ++ L K
Sbjct: 381 LEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQLAEWLDDAKQKLQQTLQK 440
Query: 256 LE---QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
E + L ++ L E +++Q+E LE+ + A+Q+ + +
Sbjct: 441 AETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEKNQELQRARQR---EKMND 497
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
D N R+ + ++ + ER+ QL LKE E+ + S+E++ + ++DEL + +
Sbjct: 498 DHNKRLSETVDKLLSESNERL-QL--HLKERMGALEEKNSLSEEIA-NMKKLQDELLLNK 553
Query: 607 DRV 615
+++
Sbjct: 554 EQL 556
>AB002376-1|BAA20832.2| 970|Homo sapiens KIAA0378 protein.
Length = 970
Score = 56.4 bits (130), Expect = 1e-07
Identities = 49/224 (21%), Positives = 104/224 (46%), Gaps = 3/224 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+Q+AA + ++ EK++ ++K +Q +D + E+R+++ L E
Sbjct: 495 EQRAAILQTEVDALRLRLEEKESFLNKKT---KQLQDLTEEKGTLAGEIRDMKDMLEVKE 551
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
+ + + K+E + L +K+KQLT L +V+ ++ D ++ T ++ L
Sbjct: 552 RKINVLQKKIENLQEQLRDKDKQLT-------NLKDRVKSLQTDSSNTDTALATLEEALS 604
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
E ++ + ++ E R + D ER++++ + KE + L E + E++ K + + D
Sbjct: 605 EKERIIE------RLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLID 658
Query: 589 ELEVAEDRVKSG---DAKISELEEELKVVGNSLKSLEVSEEKAN 711
E A +G D+K+ LE ++ LE +KA+
Sbjct: 659 LKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAH 702
Score = 44.0 bits (99), Expect = 6e-04
Identities = 56/236 (23%), Positives = 107/236 (45%), Gaps = 11/236 (4%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-VRELQKKLAQV 225
+ K + +K ++++++ + N T E+ + E++ E+ R+ +++L ++
Sbjct: 569 RDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEI 628
Query: 226 EEDLILNKNKLEQANK---DLEEKEKQLT-----ATEAEVAALNR--KVQQIEEDLEKSE 375
E NK+ E+ N +L EKE L A+ A L R K++ +E +E+ +
Sbjct: 629 ESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKK 688
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
E LEAQ N +E+ ++ + E DQ+ KEA ++
Sbjct: 689 EECSK-----LEAQLKKAHN------IEDDSRMNPEFADQIKQLDKEASYYRDECGKAQA 737
Query: 556 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
EV R L +++ E+ D KI+EL E L + ++ +V+ K NQ++E
Sbjct: 738 EVDRLLEILKE----VENEKNDKDKKIAEL-ESLTLRHMKDQNKKVANLKHNQQLE 788
Score = 31.5 bits (68), Expect = 3.2
Identities = 32/155 (20%), Positives = 71/155 (45%), Gaps = 1/155 (0%)
Frame = +1
Query: 193 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 372
+++ KK+A ++ + L K K Q +++ +E + + +++++ LEK+
Sbjct: 771 MKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHL-----QIEELMNALEKT 825
Query: 373 EERSGTAQQKLLEAQQS-ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 549
+ + +L QQS A++ + + R +Q EE ++ L A + +DA+
Sbjct: 826 RQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALL-AAISEKDANIA 884
Query: 550 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 654
E+S E +A R K D + +L+++
Sbjct: 885 LLELSASKKKKTQEEVMALKREK--DRLVHQLKQQ 917
>U25725-1|AAA86889.1| 1017|Homo sapiens AH antigen protein.
Length = 1017
Score = 56.0 bits (129), Expect = 1e-07
Identities = 39/218 (17%), Positives = 97/218 (44%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 249
D++K K++ ++ E + + + A ++ E + ++ E+ + L E DL+ +
Sbjct: 53 DSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLR 112
Query: 250 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 429
++ E K ++EK+ QL+ + +++ ++++ E+ + +E S TA + L + +
Sbjct: 113 SEKENLTKQIQEKQGQLSELDKLLSSFKSQLEEKEQAEIQIKEESKTAVEMLQNQLKELN 172
Query: 430 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 609
E + + E+ +D + + R E + + +K V +L+ +E
Sbjct: 173 EAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEH 232
Query: 610 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
++ LE EL++ + + + E + VE
Sbjct: 233 HADLLKGRVENLERELEIARTNQEHAALEAENSKGEVE 270
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/222 (18%), Positives = 92/222 (41%), Gaps = 7/222 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++ A ++ + + ++ EK+N + + Q + + ++ E ++ Q++
Sbjct: 95 EEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSQLEEKEQAEIQIK 154
Query: 229 EDLILNKNKLEQANKDLEEK-------EKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 387
E+ L+ K+L E ++ + ATE + + Q+ +EK R
Sbjct: 155 EESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLE 214
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
++K L Q E+ +L+ R + E ++ + A L AE++ G+ + +
Sbjct: 215 ADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKA 274
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 693
K+ + L E V + ++ +L EL+ + LE+
Sbjct: 275 KIEGMTQSLRGLELDVVTIRSEKEDLTNELQKEQERISELEI 316
Score = 38.7 bits (86), Expect = 0.021
Identities = 41/179 (22%), Positives = 86/179 (48%), Gaps = 16/179 (8%)
Frame = +1
Query: 190 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR-KVQQIE--ED 360
E++ ++KL EE L K +++ EE L AT + L + K+ ++
Sbjct: 627 EIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQ 686
Query: 361 LEKSEERSGTAQQKLLEA-QQSADENNRMCKVLEN-RAQQDEER--------MDQLTNQL 510
L+K ER+ + L+++ +Q +E + K L +A Q++++ +D+LT ++
Sbjct: 687 LKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEI 746
Query: 511 KEARLLAEDADGKSDEVSRK---LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL 678
KE + E+ ++DE K L ++LE A++ +++ A + + + G+ L
Sbjct: 747 KELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQVAHLCSQQSKQDSRGSPL 805
Score = 37.5 bits (83), Expect = 0.048
Identities = 40/176 (22%), Positives = 84/176 (47%), Gaps = 3/176 (1%)
Frame = +1
Query: 187 EEVRELQKKLAQVEEDL-ILNKNKLEQANKDLEE-KEKQLTATEAEVAALNRKVQQIEED 360
++++EL + +++++ L ++K+++E+ K EE E QL EAE +K Q + D
Sbjct: 565 DQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAE-----KKHQALLLD 619
Query: 361 LEKSEE-RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 537
K E T ++KL ++ +L++ ++ L N LK + E+
Sbjct: 620 TNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEE-------LNNSLKATTQILEE 672
Query: 538 ADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+ + + ++ E E A+ ++K +LEEE +++ L L+ ++EK
Sbjct: 673 LKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEK 728
Score = 35.9 bits (79), Expect = 0.15
Identities = 31/164 (18%), Positives = 72/164 (43%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
EQ NL E + ++++ LQ K A +++ L + ++ + +LE + + +V
Sbjct: 456 EQNLELRNLTVE-LEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKV 514
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
+ K +++ ++ + +++ Q++L + E NR+ L+ ++ + DQL
Sbjct: 515 NKMTAKETELQREMHEMAQKTAELQEEL------SGEKNRLAGELQLLLEEIKSSKDQLK 568
Query: 502 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAK 633
E L + D + K V +E+ + R+ + K
Sbjct: 569 ELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKK 612
Score = 35.1 bits (77), Expect = 0.26
Identities = 21/98 (21%), Positives = 46/98 (46%)
Frame = +1
Query: 400 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 579
+L Q+ + R + L R + DE++ + +LKE + K + + R+L
Sbjct: 9 RLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERDGENDSLKDKVENLERELQM 68
Query: 580 VEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 693
E+ E+ ++ A++ L+ +++ + SLK E+
Sbjct: 69 SEENQELVILDAENSKAEVETLKTQIEEMARSLKVFEL 106
>BC132736-1|AAI32737.1| 1843|Homo sapiens coiled-coil domain
containing 88A protein.
Length = 1843
Score = 56.0 bits (129), Expect = 1e-07
Identities = 56/217 (25%), Positives = 105/217 (48%), Gaps = 18/217 (8%)
Frame = +1
Query: 64 TMDAIKK-KMQAMKLEKDNAMDKADTCE-----QQARDANLRAEKVNEEVRELQKKLAQV 225
T+D+ K Q LEK+N+ + E + + A+++ ++ E +EL+ + Q+
Sbjct: 678 TLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQL 737
Query: 226 EEDLILNK------NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 387
++ L L K +LE + + L+ + ++L T + N+K+QQ+E +L+ E +
Sbjct: 738 KKGLELLKASFKKTERLEVSYQGLDIENQRLQKT---LENSNKKIQQLESELQDLEMENQ 794
Query: 388 TAQQKLLEAQQSA---DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE 558
T Q+ L E + S+ ++ + K LE Q E+ QL + K R AE D +E
Sbjct: 795 TLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEE 854
Query: 559 VSRKLAFVEDELEVAEDRV---KSGDAKISELEEELK 660
+ K+ +E E + + K ++ ELE+E K
Sbjct: 855 NNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENK 891
Score = 48.4 bits (110), Expect = 3e-05
Identities = 36/215 (16%), Positives = 104/215 (48%), Gaps = 3/215 (1%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE---EDLI 240
+ +KK ++ +K + K + E + ++ +++ + + KK+ Q+E +DL
Sbjct: 735 EQLKKGLELLKA----SFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLE 790
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
+ L++ ++L+ K+L E E +L ++ Q+E+D ++ E+ + +Q+
Sbjct: 791 MENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDT 850
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
+ +ENN V +++ + + + KE+ + ++ + ++ E+ ++ L
Sbjct: 851 TLEENN----VKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVT 906
Query: 601 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+ + S K ++ +L+ + + L+ + +++E+
Sbjct: 907 LREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKER 941
Score = 39.5 bits (88), Expect = 0.012
Identities = 46/246 (18%), Positives = 110/246 (44%), Gaps = 24/246 (9%)
Frame = +1
Query: 49 QQKAATMDAIK-KKMQAMKLEKDNAM--DKADTCEQQARDANLRAEKVNEEVRELQKKLA 219
++ T+D+++ + +K+EK+N K + E + + ++L K+ A
Sbjct: 477 EELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKA 536
Query: 220 QVEEDL-ILNKNK------LEQANKDLEE-----KEKQLTATEAEVAALNRKVQQIEEDL 363
Q+E+ + L +N LEQ N+ L + +++ + EA V + ++ + + E +
Sbjct: 537 QLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESI 596
Query: 364 EKSEERSGTAQQKLLEAQQSAD---ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 534
+++ + + + + ++ + E + LEN E+ + L ++ ++ E
Sbjct: 597 KETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCE 656
Query: 535 DADGKSDEVS------RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVS 696
+ E S RKL D + +++S + + S+L+EE + +++SL+ +
Sbjct: 657 KIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCA 716
Query: 697 EEKANQ 714
K Q
Sbjct: 717 SMKMAQ 722
Score = 30.7 bits (66), Expect = 5.5
Identities = 42/220 (19%), Positives = 95/220 (43%), Gaps = 9/220 (4%)
Frame = +1
Query: 91 QAMKLEKDNAMDKADTCEQQARDANL-----RAEKVNEEVRELQKKLAQVEEDLILNKNK 255
Q KL+ +N+ + + ++A L E NE V + ++ L + + LI + K
Sbjct: 1103 QNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEK 1162
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
LE ++ + + L + + + ++ ++ DLE +LL+ + ++
Sbjct: 1163 LELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLE-------DRYNQLLKQKGQLEDL 1215
Query: 436 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 615
+M KV + + + + + + + K+ L + D + S+ L E L+ +
Sbjct: 1216 EKMLKVEQEKMLLENKNHETVAAEYKK---LCGENDRLNHTYSQLLKETE-VLQTDHKNL 1271
Query: 616 KS--GDAKISE--LEEELKVVGNSLKSLEVSEEKANQRVE 723
KS ++K+ + LE E + + L+++ K N + E
Sbjct: 1272 KSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCE 1311
>AY480051-1|AAR95684.1| 4547|Homo sapiens plectin 11 protein.
Length = 4547
Score = 56.0 bits (129), Expect = 1e-07
Identities = 49/204 (24%), Positives = 94/204 (46%), Gaps = 2/204 (0%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
+ NA D + EQ +A + + EE R ++ +V++ L + Q LEE
Sbjct: 1952 RSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 2011
Query: 289 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV--LEN 462
E+ +A+V R ++ E++ + + + A QK L+A++ A K L+
Sbjct: 2012 ER----LKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 2067
Query: 463 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE 642
QQ++ +DQL + + AR AE+A+ + R+ A ++E AE R+K + ++
Sbjct: 2068 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE-RLKQSAEEQAQ 2126
Query: 643 LEEELKVVGNSLKSLEVSEEKANQ 714
+ + L+ E +E A +
Sbjct: 2127 ARAQAQAAAEKLRK-EAEQEAARR 2149
Score = 49.2 bits (112), Expect = 1e-05
Identities = 48/229 (20%), Positives = 110/229 (48%), Gaps = 10/229 (4%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNA-MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE---E 231
T++A +++ M E + + A+ QAR A A++ ++ E+ +KL + E +
Sbjct: 2367 TLEAERQRQLEMSAEAERLKLRVAEMSRAQAR-AEEDAQRFRKQAEEIGEKLHRTELATQ 2425
Query: 232 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTAQQKLL 408
+ + LE + + ++L AE+ K+QQ + L+ KSEE Q++LL
Sbjct: 2426 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLL 2485
Query: 409 EAQQSADEN--NRMCKVLENRA--QQDEERMDQL-TNQLKEARLLAEDADGKSDEVSRKL 573
+ Q+ ++ + +L+ +Q++ +++QL +++ +A+ L E+ + ++ ++
Sbjct: 2486 QETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQER 2545
Query: 574 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ +E A R + + +EEL+ + + E + NQR+
Sbjct: 2546 QRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRL 2594
Score = 48.0 bits (109), Expect = 3e-05
Identities = 54/223 (24%), Positives = 104/223 (46%), Gaps = 12/223 (5%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKK---LAQVEEDLILNKN 252
++ + +++ + A A+ E Q++ A+ AEK + R LQ++ +AQ+ E+
Sbjct: 1558 ERARQVQVALETAQRSAEA-ELQSKRASF-AEKTAQLERSLQEEHVAVAQLREEAERRAQ 1615
Query: 253 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 432
+ +A + EE E++L + + R Q EE ++ A+++ EA++ A
Sbjct: 1616 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARR 1675
Query: 433 NNRMCK-VLENR--AQQDEERMDQLTNQLKEARLLAED------ADGKSDEVSRKLAFVE 585
+ + + R A+Q+ E+ QL + RL AE A+ + E R+L +E
Sbjct: 1676 RGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQL--LE 1733
Query: 586 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
+EL + + K ELE EL V ++ L S+ +A +
Sbjct: 1734 EELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEE 1776
Score = 44.8 bits (101), Expect = 3e-04
Identities = 47/206 (22%), Positives = 81/206 (39%), Gaps = 3/206 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN-EEVRELQKKL--A 219
Q + +K + +A + EK A+ + QA +A R + E R++Q L A
Sbjct: 1512 QAEVELASRVKAEAEAAR-EKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETA 1570
Query: 220 QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 399
Q + L + A K + E+ L VA L + ++ + ++E A++
Sbjct: 1571 QRSAEAELQSKRASFAEKTAQ-LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAER 1629
Query: 400 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 579
+L Q A+E R+ E AQQ + Q +EA A ++ R+
Sbjct: 1630 ELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQREL 1689
Query: 580 VEDELEVAEDRVKSGDAKISELEEEL 657
E ELE + + E+EL
Sbjct: 1690 AEQELEKQRQLAEGTAQQRLAAEQEL 1715
Score = 39.9 bits (89), Expect = 0.009
Identities = 55/229 (24%), Positives = 98/229 (42%), Gaps = 6/229 (2%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKA-DTCEQQARDANLRAEKVNEEVRELQKKLAQV 225
Q+ A + ++ +M+ + K A +++ T E+ + A + E E + A
Sbjct: 1751 QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALA 1810
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
EE + E A + E E+ L A + R + E L K +E ++L
Sbjct: 1811 EEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL-KEKEAENERLRRL 1869
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
A+ A + R+ + EER+ QL + ++ L E G ++ R+ VE
Sbjct: 1870 --AEDEAFQRRRLEEQAAQHKADIEERLAQL-RKASDSEL--ERQKGLVEDTLRQRRQVE 1924
Query: 586 DELEVAEDRVKSGDAKISELEEEL-KVVGN---SLKSLEVSE-EKANQR 717
+E+ + + A +ELE EL ++ N +L+S E +E E A QR
Sbjct: 1925 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQR 1973
Score = 37.5 bits (83), Expect = 0.048
Identities = 33/147 (22%), Positives = 71/147 (48%), Gaps = 5/147 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQ---ARDANLRAEKVNEEVRELQKKLA 219
QQ+A + ++MQ ++ E+ + + +Q +D+ L+ E+ E+ + KL
Sbjct: 2463 QQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQEKA---KLE 2517
Query: 220 QVEEDLILNKNKL-EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTA 393
Q+ +D + +L E+ + ++ E++ A + R+ + EE + K EE
Sbjct: 2518 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2577
Query: 394 QQKLLEAQQSADENNRMCKVLENRAQQ 474
QQ+ + + A+EN R+ + L+ +Q
Sbjct: 2578 QQRRQQEELLAEENQRLREQLQLLEEQ 2604
Score = 37.1 bits (82), Expect = 0.064
Identities = 30/131 (22%), Positives = 63/131 (48%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+ +A + +K ++ E+ +KA EQ +D +A+++ EE + Q+++ Q
Sbjct: 2487 ETQALQQSFLSEKDSLLQRERFIEQEKAKL-EQLFQDEVAKAQQLREEQQRQQQQMEQER 2545
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
+ L+ + +E+A + E E+ + + E+ QQ+E+ + EE Q+L
Sbjct: 2546 QRLVAS---MEEARRRQHEAEEGVRRKQEEL-------QQLEQQRRQQEELLAEENQRLR 2595
Query: 409 EAQQSADENNR 441
E Q +E +R
Sbjct: 2596 EQLQLLEEQHR 2606
Score = 36.7 bits (81), Expect = 0.084
Identities = 46/214 (21%), Positives = 91/214 (42%), Gaps = 12/214 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
Q A M+ KK + +K + T Q + + + ++EE++ L+ + +
Sbjct: 2161 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2220
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL-----NRKVQQIEEDLEKSEE----- 378
+ +L +EE K EAE AL + + ++E+ EK ++
Sbjct: 2221 RQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2280
Query: 379 -RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK-EARLLAEDADGKS 552
R A Q+ +Q A+E+ + L + +++ + Q +LK EA LL + + +
Sbjct: 2281 ARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LA 2339
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 654
E +R+L ED+ ++A+ + LE E
Sbjct: 2340 QEQARRLQ--EDKEQMAQQLAEETQGFQRTLEAE 2371
Score = 35.1 bits (77), Expect = 0.26
Identities = 39/224 (17%), Positives = 97/224 (43%), Gaps = 2/224 (0%)
Frame = +1
Query: 58 AATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL 237
AA +A +++ A++ E + K + + A + + + +E +K Q EE
Sbjct: 1995 AAEEEAARQRKAALE-EVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKA 2053
Query: 238 --ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 411
+ K ++ + L++++ L E A R ++ EE ++E + +++++ E
Sbjct: 2054 HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEE 2113
Query: 412 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 591
A++ + +AQ E++ + Q R AE A + + + A +E
Sbjct: 2114 AERLKQSAEEQAQA-RAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAAD--AEMEKH 2170
Query: 592 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ AE ++ +++E+EL + L+ + + ++ ++
Sbjct: 2171 KKFAEQTLRQK----AQVEQELTTLRLQLEETDHQKNLLDEELQ 2210
>AY480050-1|AAR95683.1| 4551|Homo sapiens plectin 10 protein.
Length = 4551
Score = 56.0 bits (129), Expect = 1e-07
Identities = 49/204 (24%), Positives = 94/204 (46%), Gaps = 2/204 (0%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
+ NA D + EQ +A + + EE R ++ +V++ L + Q LEE
Sbjct: 1956 RSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 2015
Query: 289 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV--LEN 462
E+ +A+V R ++ E++ + + + A QK L+A++ A K L+
Sbjct: 2016 ER----LKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 2071
Query: 463 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE 642
QQ++ +DQL + + AR AE+A+ + R+ A ++E AE R+K + ++
Sbjct: 2072 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE-RLKQSAEEQAQ 2130
Query: 643 LEEELKVVGNSLKSLEVSEEKANQ 714
+ + L+ E +E A +
Sbjct: 2131 ARAQAQAAAEKLRK-EAEQEAARR 2153
Score = 49.2 bits (112), Expect = 1e-05
Identities = 48/229 (20%), Positives = 110/229 (48%), Gaps = 10/229 (4%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNA-MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE---E 231
T++A +++ M E + + A+ QAR A A++ ++ E+ +KL + E +
Sbjct: 2371 TLEAERQRQLEMSAEAERLKLRVAEMSRAQAR-AEEDAQRFRKQAEEIGEKLHRTELATQ 2429
Query: 232 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTAQQKLL 408
+ + LE + + ++L AE+ K+QQ + L+ KSEE Q++LL
Sbjct: 2430 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLL 2489
Query: 409 EAQQSADEN--NRMCKVLENRA--QQDEERMDQL-TNQLKEARLLAEDADGKSDEVSRKL 573
+ Q+ ++ + +L+ +Q++ +++QL +++ +A+ L E+ + ++ ++
Sbjct: 2490 QETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQER 2549
Query: 574 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ +E A R + + +EEL+ + + E + NQR+
Sbjct: 2550 QRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRL 2598
Score = 48.0 bits (109), Expect = 3e-05
Identities = 54/223 (24%), Positives = 104/223 (46%), Gaps = 12/223 (5%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKK---LAQVEEDLILNKN 252
++ + +++ + A A+ E Q++ A+ AEK + R LQ++ +AQ+ E+
Sbjct: 1562 ERARQVQVALETAQRSAEA-ELQSKRASF-AEKTAQLERSLQEEHVAVAQLREEAERRAQ 1619
Query: 253 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 432
+ +A + EE E++L + + R Q EE ++ A+++ EA++ A
Sbjct: 1620 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARR 1679
Query: 433 NNRMCK-VLENR--AQQDEERMDQLTNQLKEARLLAED------ADGKSDEVSRKLAFVE 585
+ + + R A+Q+ E+ QL + RL AE A+ + E R+L +E
Sbjct: 1680 RGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQL--LE 1737
Query: 586 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
+EL + + K ELE EL V ++ L S+ +A +
Sbjct: 1738 EELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEE 1780
Score = 44.8 bits (101), Expect = 3e-04
Identities = 47/206 (22%), Positives = 81/206 (39%), Gaps = 3/206 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN-EEVRELQKKL--A 219
Q + +K + +A + EK A+ + QA +A R + E R++Q L A
Sbjct: 1516 QAEVELASRVKAEAEAAR-EKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETA 1574
Query: 220 QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 399
Q + L + A K + E+ L VA L + ++ + ++E A++
Sbjct: 1575 QRSAEAELQSKRASFAEKTAQ-LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAER 1633
Query: 400 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 579
+L Q A+E R+ E AQQ + Q +EA A ++ R+
Sbjct: 1634 ELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQREL 1693
Query: 580 VEDELEVAEDRVKSGDAKISELEEEL 657
E ELE + + E+EL
Sbjct: 1694 AEQELEKQRQLAEGTAQQRLAAEQEL 1719
Score = 39.9 bits (89), Expect = 0.009
Identities = 55/229 (24%), Positives = 98/229 (42%), Gaps = 6/229 (2%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKA-DTCEQQARDANLRAEKVNEEVRELQKKLAQV 225
Q+ A + ++ +M+ + K A +++ T E+ + A + E E + A
Sbjct: 1755 QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALA 1814
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
EE + E A + E E+ L A + R + E L K +E ++L
Sbjct: 1815 EEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL-KEKEAENERLRRL 1873
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
A+ A + R+ + EER+ QL + ++ L E G ++ R+ VE
Sbjct: 1874 --AEDEAFQRRRLEEQAAQHKADIEERLAQL-RKASDSEL--ERQKGLVEDTLRQRRQVE 1928
Query: 586 DELEVAEDRVKSGDAKISELEEEL-KVVGN---SLKSLEVSE-EKANQR 717
+E+ + + A +ELE EL ++ N +L+S E +E E A QR
Sbjct: 1929 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQR 1977
Score = 37.5 bits (83), Expect = 0.048
Identities = 33/147 (22%), Positives = 71/147 (48%), Gaps = 5/147 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQ---ARDANLRAEKVNEEVRELQKKLA 219
QQ+A + ++MQ ++ E+ + + +Q +D+ L+ E+ E+ + KL
Sbjct: 2467 QQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQEKA---KLE 2521
Query: 220 QVEEDLILNKNKL-EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTA 393
Q+ +D + +L E+ + ++ E++ A + R+ + EE + K EE
Sbjct: 2522 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2581
Query: 394 QQKLLEAQQSADENNRMCKVLENRAQQ 474
QQ+ + + A+EN R+ + L+ +Q
Sbjct: 2582 QQRRQQEELLAEENQRLREQLQLLEEQ 2608
Score = 37.1 bits (82), Expect = 0.064
Identities = 30/131 (22%), Positives = 63/131 (48%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+ +A + +K ++ E+ +KA EQ +D +A+++ EE + Q+++ Q
Sbjct: 2491 ETQALQQSFLSEKDSLLQRERFIEQEKAKL-EQLFQDEVAKAQQLREEQQRQQQQMEQER 2549
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
+ L+ + +E+A + E E+ + + E+ QQ+E+ + EE Q+L
Sbjct: 2550 QRLVAS---MEEARRRQHEAEEGVRRKQEEL-------QQLEQQRRQQEELLAEENQRLR 2599
Query: 409 EAQQSADENNR 441
E Q +E +R
Sbjct: 2600 EQLQLLEEQHR 2610
Score = 36.7 bits (81), Expect = 0.084
Identities = 46/214 (21%), Positives = 91/214 (42%), Gaps = 12/214 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
Q A M+ KK + +K + T Q + + + ++EE++ L+ + +
Sbjct: 2165 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2224
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL-----NRKVQQIEEDLEKSEE----- 378
+ +L +EE K EAE AL + + ++E+ EK ++
Sbjct: 2225 RQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2284
Query: 379 -RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK-EARLLAEDADGKS 552
R A Q+ +Q A+E+ + L + +++ + Q +LK EA LL + + +
Sbjct: 2285 ARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LA 2343
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 654
E +R+L ED+ ++A+ + LE E
Sbjct: 2344 QEQARRLQ--EDKEQMAQQLAEETQGFQRTLEAE 2375
Score = 35.1 bits (77), Expect = 0.26
Identities = 39/224 (17%), Positives = 97/224 (43%), Gaps = 2/224 (0%)
Frame = +1
Query: 58 AATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL 237
AA +A +++ A++ E + K + + A + + + +E +K Q EE
Sbjct: 1999 AAEEEAARQRKAALE-EVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKA 2057
Query: 238 --ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 411
+ K ++ + L++++ L E A R ++ EE ++E + +++++ E
Sbjct: 2058 HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEE 2117
Query: 412 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 591
A++ + +AQ E++ + Q R AE A + + + A +E
Sbjct: 2118 AERLKQSAEEQAQA-RAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAAD--AEMEKH 2174
Query: 592 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ AE ++ +++E+EL + L+ + + ++ ++
Sbjct: 2175 KKFAEQTLRQK----AQVEQELTTLRLQLEETDHQKNLLDEELQ 2214
>AY480049-1|AAR95682.1| 4547|Homo sapiens plectin 8 protein.
Length = 4547
Score = 56.0 bits (129), Expect = 1e-07
Identities = 49/204 (24%), Positives = 94/204 (46%), Gaps = 2/204 (0%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
+ NA D + EQ +A + + EE R ++ +V++ L + Q LEE
Sbjct: 1952 RSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 2011
Query: 289 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV--LEN 462
E+ +A+V R ++ E++ + + + A QK L+A++ A K L+
Sbjct: 2012 ER----LKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 2067
Query: 463 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE 642
QQ++ +DQL + + AR AE+A+ + R+ A ++E AE R+K + ++
Sbjct: 2068 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE-RLKQSAEEQAQ 2126
Query: 643 LEEELKVVGNSLKSLEVSEEKANQ 714
+ + L+ E +E A +
Sbjct: 2127 ARAQAQAAAEKLRK-EAEQEAARR 2149
Score = 49.2 bits (112), Expect = 1e-05
Identities = 48/229 (20%), Positives = 110/229 (48%), Gaps = 10/229 (4%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNA-MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE---E 231
T++A +++ M E + + A+ QAR A A++ ++ E+ +KL + E +
Sbjct: 2367 TLEAERQRQLEMSAEAERLKLRVAEMSRAQAR-AEEDAQRFRKQAEEIGEKLHRTELATQ 2425
Query: 232 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTAQQKLL 408
+ + LE + + ++L AE+ K+QQ + L+ KSEE Q++LL
Sbjct: 2426 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLL 2485
Query: 409 EAQQSADEN--NRMCKVLENRA--QQDEERMDQL-TNQLKEARLLAEDADGKSDEVSRKL 573
+ Q+ ++ + +L+ +Q++ +++QL +++ +A+ L E+ + ++ ++
Sbjct: 2486 QETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQER 2545
Query: 574 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ +E A R + + +EEL+ + + E + NQR+
Sbjct: 2546 QRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRL 2594
Score = 48.0 bits (109), Expect = 3e-05
Identities = 54/223 (24%), Positives = 104/223 (46%), Gaps = 12/223 (5%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKK---LAQVEEDLILNKN 252
++ + +++ + A A+ E Q++ A+ AEK + R LQ++ +AQ+ E+
Sbjct: 1558 ERARQVQVALETAQRSAEA-ELQSKRASF-AEKTAQLERSLQEEHVAVAQLREEAERRAQ 1615
Query: 253 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 432
+ +A + EE E++L + + R Q EE ++ A+++ EA++ A
Sbjct: 1616 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARR 1675
Query: 433 NNRMCK-VLENR--AQQDEERMDQLTNQLKEARLLAED------ADGKSDEVSRKLAFVE 585
+ + + R A+Q+ E+ QL + RL AE A+ + E R+L +E
Sbjct: 1676 RGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQL--LE 1733
Query: 586 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
+EL + + K ELE EL V ++ L S+ +A +
Sbjct: 1734 EELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEE 1776
Score = 44.8 bits (101), Expect = 3e-04
Identities = 47/206 (22%), Positives = 81/206 (39%), Gaps = 3/206 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN-EEVRELQKKL--A 219
Q + +K + +A + EK A+ + QA +A R + E R++Q L A
Sbjct: 1512 QAEVELASRVKAEAEAAR-EKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETA 1570
Query: 220 QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 399
Q + L + A K + E+ L VA L + ++ + ++E A++
Sbjct: 1571 QRSAEAELQSKRASFAEKTAQ-LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAER 1629
Query: 400 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 579
+L Q A+E R+ E AQQ + Q +EA A ++ R+
Sbjct: 1630 ELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQREL 1689
Query: 580 VEDELEVAEDRVKSGDAKISELEEEL 657
E ELE + + E+EL
Sbjct: 1690 AEQELEKQRQLAEGTAQQRLAAEQEL 1715
Score = 39.9 bits (89), Expect = 0.009
Identities = 55/229 (24%), Positives = 98/229 (42%), Gaps = 6/229 (2%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKA-DTCEQQARDANLRAEKVNEEVRELQKKLAQV 225
Q+ A + ++ +M+ + K A +++ T E+ + A + E E + A
Sbjct: 1751 QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALA 1810
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
EE + E A + E E+ L A + R + E L K +E ++L
Sbjct: 1811 EEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL-KEKEAENERLRRL 1869
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
A+ A + R+ + EER+ QL + ++ L E G ++ R+ VE
Sbjct: 1870 --AEDEAFQRRRLEEQAAQHKADIEERLAQL-RKASDSEL--ERQKGLVEDTLRQRRQVE 1924
Query: 586 DELEVAEDRVKSGDAKISELEEEL-KVVGN---SLKSLEVSE-EKANQR 717
+E+ + + A +ELE EL ++ N +L+S E +E E A QR
Sbjct: 1925 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQR 1973
Score = 37.5 bits (83), Expect = 0.048
Identities = 33/147 (22%), Positives = 71/147 (48%), Gaps = 5/147 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQ---ARDANLRAEKVNEEVRELQKKLA 219
QQ+A + ++MQ ++ E+ + + +Q +D+ L+ E+ E+ + KL
Sbjct: 2463 QQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQEKA---KLE 2517
Query: 220 QVEEDLILNKNKL-EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTA 393
Q+ +D + +L E+ + ++ E++ A + R+ + EE + K EE
Sbjct: 2518 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2577
Query: 394 QQKLLEAQQSADENNRMCKVLENRAQQ 474
QQ+ + + A+EN R+ + L+ +Q
Sbjct: 2578 QQRRQQEELLAEENQRLREQLQLLEEQ 2604
Score = 37.1 bits (82), Expect = 0.064
Identities = 30/131 (22%), Positives = 63/131 (48%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+ +A + +K ++ E+ +KA EQ +D +A+++ EE + Q+++ Q
Sbjct: 2487 ETQALQQSFLSEKDSLLQRERFIEQEKAKL-EQLFQDEVAKAQQLREEQQRQQQQMEQER 2545
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
+ L+ + +E+A + E E+ + + E+ QQ+E+ + EE Q+L
Sbjct: 2546 QRLVAS---MEEARRRQHEAEEGVRRKQEEL-------QQLEQQRRQQEELLAEENQRLR 2595
Query: 409 EAQQSADENNR 441
E Q +E +R
Sbjct: 2596 EQLQLLEEQHR 2606
Score = 36.7 bits (81), Expect = 0.084
Identities = 46/214 (21%), Positives = 91/214 (42%), Gaps = 12/214 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
Q A M+ KK + +K + T Q + + + ++EE++ L+ + +
Sbjct: 2161 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2220
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL-----NRKVQQIEEDLEKSEE----- 378
+ +L +EE K EAE AL + + ++E+ EK ++
Sbjct: 2221 RQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2280
Query: 379 -RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK-EARLLAEDADGKS 552
R A Q+ +Q A+E+ + L + +++ + Q +LK EA LL + + +
Sbjct: 2281 ARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LA 2339
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 654
E +R+L ED+ ++A+ + LE E
Sbjct: 2340 QEQARRLQ--EDKEQMAQQLAEETQGFQRTLEAE 2371
Score = 35.1 bits (77), Expect = 0.26
Identities = 39/224 (17%), Positives = 97/224 (43%), Gaps = 2/224 (0%)
Frame = +1
Query: 58 AATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL 237
AA +A +++ A++ E + K + + A + + + +E +K Q EE
Sbjct: 1995 AAEEEAARQRKAALE-EVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKA 2053
Query: 238 --ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 411
+ K ++ + L++++ L E A R ++ EE ++E + +++++ E
Sbjct: 2054 HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEE 2113
Query: 412 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 591
A++ + +AQ E++ + Q R AE A + + + A +E
Sbjct: 2114 AERLKQSAEEQAQA-RAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAAD--AEMEKH 2170
Query: 592 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ AE ++ +++E+EL + L+ + + ++ ++
Sbjct: 2171 KKFAEQTLRQK----AQVEQELTTLRLQLEETDHQKNLLDEELQ 2210
>AY480048-1|AAR95681.1| 4515|Homo sapiens plectin 7 protein.
Length = 4515
Score = 56.0 bits (129), Expect = 1e-07
Identities = 49/204 (24%), Positives = 94/204 (46%), Gaps = 2/204 (0%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
+ NA D + EQ +A + + EE R ++ +V++ L + Q LEE
Sbjct: 1920 RSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 1979
Query: 289 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV--LEN 462
E+ +A+V R ++ E++ + + + A QK L+A++ A K L+
Sbjct: 1980 ER----LKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 2035
Query: 463 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE 642
QQ++ +DQL + + AR AE+A+ + R+ A ++E AE R+K + ++
Sbjct: 2036 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE-RLKQSAEEQAQ 2094
Query: 643 LEEELKVVGNSLKSLEVSEEKANQ 714
+ + L+ E +E A +
Sbjct: 2095 ARAQAQAAAEKLRK-EAEQEAARR 2117
Score = 49.2 bits (112), Expect = 1e-05
Identities = 48/229 (20%), Positives = 110/229 (48%), Gaps = 10/229 (4%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNA-MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE---E 231
T++A +++ M E + + A+ QAR A A++ ++ E+ +KL + E +
Sbjct: 2335 TLEAERQRQLEMSAEAERLKLRVAEMSRAQAR-AEEDAQRFRKQAEEIGEKLHRTELATQ 2393
Query: 232 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTAQQKLL 408
+ + LE + + ++L AE+ K+QQ + L+ KSEE Q++LL
Sbjct: 2394 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLL 2453
Query: 409 EAQQSADEN--NRMCKVLENRA--QQDEERMDQL-TNQLKEARLLAEDADGKSDEVSRKL 573
+ Q+ ++ + +L+ +Q++ +++QL +++ +A+ L E+ + ++ ++
Sbjct: 2454 QETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQER 2513
Query: 574 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ +E A R + + +EEL+ + + E + NQR+
Sbjct: 2514 QRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRL 2562
Score = 48.0 bits (109), Expect = 3e-05
Identities = 54/223 (24%), Positives = 104/223 (46%), Gaps = 12/223 (5%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKK---LAQVEEDLILNKN 252
++ + +++ + A A+ E Q++ A+ AEK + R LQ++ +AQ+ E+
Sbjct: 1526 ERARQVQVALETAQRSAEA-ELQSKRASF-AEKTAQLERSLQEEHVAVAQLREEAERRAQ 1583
Query: 253 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 432
+ +A + EE E++L + + R Q EE ++ A+++ EA++ A
Sbjct: 1584 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARR 1643
Query: 433 NNRMCK-VLENR--AQQDEERMDQLTNQLKEARLLAED------ADGKSDEVSRKLAFVE 585
+ + + R A+Q+ E+ QL + RL AE A+ + E R+L +E
Sbjct: 1644 RGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQL--LE 1701
Query: 586 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
+EL + + K ELE EL V ++ L S+ +A +
Sbjct: 1702 EELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEE 1744
Score = 44.8 bits (101), Expect = 3e-04
Identities = 47/206 (22%), Positives = 81/206 (39%), Gaps = 3/206 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN-EEVRELQKKL--A 219
Q + +K + +A + EK A+ + QA +A R + E R++Q L A
Sbjct: 1480 QAEVELASRVKAEAEAAR-EKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETA 1538
Query: 220 QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 399
Q + L + A K + E+ L VA L + ++ + ++E A++
Sbjct: 1539 QRSAEAELQSKRASFAEKTAQ-LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAER 1597
Query: 400 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 579
+L Q A+E R+ E AQQ + Q +EA A ++ R+
Sbjct: 1598 ELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQREL 1657
Query: 580 VEDELEVAEDRVKSGDAKISELEEEL 657
E ELE + + E+EL
Sbjct: 1658 AEQELEKQRQLAEGTAQQRLAAEQEL 1683
Score = 39.9 bits (89), Expect = 0.009
Identities = 55/229 (24%), Positives = 98/229 (42%), Gaps = 6/229 (2%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKA-DTCEQQARDANLRAEKVNEEVRELQKKLAQV 225
Q+ A + ++ +M+ + K A +++ T E+ + A + E E + A
Sbjct: 1719 QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALA 1778
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
EE + E A + E E+ L A + R + E L K +E ++L
Sbjct: 1779 EEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL-KEKEAENERLRRL 1837
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
A+ A + R+ + EER+ QL + ++ L E G ++ R+ VE
Sbjct: 1838 --AEDEAFQRRRLEEQAAQHKADIEERLAQL-RKASDSEL--ERQKGLVEDTLRQRRQVE 1892
Query: 586 DELEVAEDRVKSGDAKISELEEEL-KVVGN---SLKSLEVSE-EKANQR 717
+E+ + + A +ELE EL ++ N +L+S E +E E A QR
Sbjct: 1893 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQR 1941
Score = 37.5 bits (83), Expect = 0.048
Identities = 33/147 (22%), Positives = 71/147 (48%), Gaps = 5/147 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQ---ARDANLRAEKVNEEVRELQKKLA 219
QQ+A + ++MQ ++ E+ + + +Q +D+ L+ E+ E+ + KL
Sbjct: 2431 QQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQEKA---KLE 2485
Query: 220 QVEEDLILNKNKL-EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTA 393
Q+ +D + +L E+ + ++ E++ A + R+ + EE + K EE
Sbjct: 2486 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2545
Query: 394 QQKLLEAQQSADENNRMCKVLENRAQQ 474
QQ+ + + A+EN R+ + L+ +Q
Sbjct: 2546 QQRRQQEELLAEENQRLREQLQLLEEQ 2572
Score = 37.1 bits (82), Expect = 0.064
Identities = 30/131 (22%), Positives = 63/131 (48%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+ +A + +K ++ E+ +KA EQ +D +A+++ EE + Q+++ Q
Sbjct: 2455 ETQALQQSFLSEKDSLLQRERFIEQEKAKL-EQLFQDEVAKAQQLREEQQRQQQQMEQER 2513
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
+ L+ + +E+A + E E+ + + E+ QQ+E+ + EE Q+L
Sbjct: 2514 QRLVAS---MEEARRRQHEAEEGVRRKQEEL-------QQLEQQRRQQEELLAEENQRLR 2563
Query: 409 EAQQSADENNR 441
E Q +E +R
Sbjct: 2564 EQLQLLEEQHR 2574
Score = 36.7 bits (81), Expect = 0.084
Identities = 46/214 (21%), Positives = 91/214 (42%), Gaps = 12/214 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
Q A M+ KK + +K + T Q + + + ++EE++ L+ + +
Sbjct: 2129 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2188
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL-----NRKVQQIEEDLEKSEE----- 378
+ +L +EE K EAE AL + + ++E+ EK ++
Sbjct: 2189 RQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2248
Query: 379 -RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK-EARLLAEDADGKS 552
R A Q+ +Q A+E+ + L + +++ + Q +LK EA LL + + +
Sbjct: 2249 ARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LA 2307
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 654
E +R+L ED+ ++A+ + LE E
Sbjct: 2308 QEQARRLQ--EDKEQMAQQLAEETQGFQRTLEAE 2339
Score = 35.1 bits (77), Expect = 0.26
Identities = 39/224 (17%), Positives = 97/224 (43%), Gaps = 2/224 (0%)
Frame = +1
Query: 58 AATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL 237
AA +A +++ A++ E + K + + A + + + +E +K Q EE
Sbjct: 1963 AAEEEAARQRKAALE-EVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKA 2021
Query: 238 --ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 411
+ K ++ + L++++ L E A R ++ EE ++E + +++++ E
Sbjct: 2022 HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEE 2081
Query: 412 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 591
A++ + +AQ E++ + Q R AE A + + + A +E
Sbjct: 2082 AERLKQSAEEQAQA-RAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAAD--AEMEKH 2138
Query: 592 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ AE ++ +++E+EL + L+ + + ++ ++
Sbjct: 2139 KKFAEQTLRQK----AQVEQELTTLRLQLEETDHQKNLLDEELQ 2178
>AY480047-1|AAR95680.1| 4684|Homo sapiens plectin 6 protein.
Length = 4684
Score = 56.0 bits (129), Expect = 1e-07
Identities = 49/204 (24%), Positives = 94/204 (46%), Gaps = 2/204 (0%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
+ NA D + EQ +A + + EE R ++ +V++ L + Q LEE
Sbjct: 2089 RSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 2148
Query: 289 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV--LEN 462
E+ +A+V R ++ E++ + + + A QK L+A++ A K L+
Sbjct: 2149 ER----LKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 2204
Query: 463 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE 642
QQ++ +DQL + + AR AE+A+ + R+ A ++E AE R+K + ++
Sbjct: 2205 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE-RLKQSAEEQAQ 2263
Query: 643 LEEELKVVGNSLKSLEVSEEKANQ 714
+ + L+ E +E A +
Sbjct: 2264 ARAQAQAAAEKLRK-EAEQEAARR 2286
Score = 49.2 bits (112), Expect = 1e-05
Identities = 48/229 (20%), Positives = 110/229 (48%), Gaps = 10/229 (4%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNA-MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE---E 231
T++A +++ M E + + A+ QAR A A++ ++ E+ +KL + E +
Sbjct: 2504 TLEAERQRQLEMSAEAERLKLRVAEMSRAQAR-AEEDAQRFRKQAEEIGEKLHRTELATQ 2562
Query: 232 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTAQQKLL 408
+ + LE + + ++L AE+ K+QQ + L+ KSEE Q++LL
Sbjct: 2563 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLL 2622
Query: 409 EAQQSADEN--NRMCKVLENRA--QQDEERMDQL-TNQLKEARLLAEDADGKSDEVSRKL 573
+ Q+ ++ + +L+ +Q++ +++QL +++ +A+ L E+ + ++ ++
Sbjct: 2623 QETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQER 2682
Query: 574 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ +E A R + + +EEL+ + + E + NQR+
Sbjct: 2683 QRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRL 2731
Score = 48.0 bits (109), Expect = 3e-05
Identities = 54/223 (24%), Positives = 104/223 (46%), Gaps = 12/223 (5%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKK---LAQVEEDLILNKN 252
++ + +++ + A A+ E Q++ A+ AEK + R LQ++ +AQ+ E+
Sbjct: 1695 ERARQVQVALETAQRSAEA-ELQSKRASF-AEKTAQLERSLQEEHVAVAQLREEAERRAQ 1752
Query: 253 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 432
+ +A + EE E++L + + R Q EE ++ A+++ EA++ A
Sbjct: 1753 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARR 1812
Query: 433 NNRMCK-VLENR--AQQDEERMDQLTNQLKEARLLAED------ADGKSDEVSRKLAFVE 585
+ + + R A+Q+ E+ QL + RL AE A+ + E R+L +E
Sbjct: 1813 RGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQL--LE 1870
Query: 586 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
+EL + + K ELE EL V ++ L S+ +A +
Sbjct: 1871 EELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEE 1913
Score = 44.8 bits (101), Expect = 3e-04
Identities = 47/206 (22%), Positives = 81/206 (39%), Gaps = 3/206 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN-EEVRELQKKL--A 219
Q + +K + +A + EK A+ + QA +A R + E R++Q L A
Sbjct: 1649 QAEVELASRVKAEAEAAR-EKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETA 1707
Query: 220 QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 399
Q + L + A K + E+ L VA L + ++ + ++E A++
Sbjct: 1708 QRSAEAELQSKRASFAEKTAQ-LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAER 1766
Query: 400 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 579
+L Q A+E R+ E AQQ + Q +EA A ++ R+
Sbjct: 1767 ELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQREL 1826
Query: 580 VEDELEVAEDRVKSGDAKISELEEEL 657
E ELE + + E+EL
Sbjct: 1827 AEQELEKQRQLAEGTAQQRLAAEQEL 1852
Score = 39.9 bits (89), Expect = 0.009
Identities = 55/229 (24%), Positives = 98/229 (42%), Gaps = 6/229 (2%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKA-DTCEQQARDANLRAEKVNEEVRELQKKLAQV 225
Q+ A + ++ +M+ + K A +++ T E+ + A + E E + A
Sbjct: 1888 QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALA 1947
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
EE + E A + E E+ L A + R + E L K +E ++L
Sbjct: 1948 EEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL-KEKEAENERLRRL 2006
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
A+ A + R+ + EER+ QL + ++ L E G ++ R+ VE
Sbjct: 2007 --AEDEAFQRRRLEEQAAQHKADIEERLAQL-RKASDSEL--ERQKGLVEDTLRQRRQVE 2061
Query: 586 DELEVAEDRVKSGDAKISELEEEL-KVVGN---SLKSLEVSE-EKANQR 717
+E+ + + A +ELE EL ++ N +L+S E +E E A QR
Sbjct: 2062 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQR 2110
Score = 37.5 bits (83), Expect = 0.048
Identities = 33/147 (22%), Positives = 71/147 (48%), Gaps = 5/147 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQ---ARDANLRAEKVNEEVRELQKKLA 219
QQ+A + ++MQ ++ E+ + + +Q +D+ L+ E+ E+ + KL
Sbjct: 2600 QQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQEKA---KLE 2654
Query: 220 QVEEDLILNKNKL-EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTA 393
Q+ +D + +L E+ + ++ E++ A + R+ + EE + K EE
Sbjct: 2655 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2714
Query: 394 QQKLLEAQQSADENNRMCKVLENRAQQ 474
QQ+ + + A+EN R+ + L+ +Q
Sbjct: 2715 QQRRQQEELLAEENQRLREQLQLLEEQ 2741
Score = 37.1 bits (82), Expect = 0.064
Identities = 30/131 (22%), Positives = 63/131 (48%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+ +A + +K ++ E+ +KA EQ +D +A+++ EE + Q+++ Q
Sbjct: 2624 ETQALQQSFLSEKDSLLQRERFIEQEKAKL-EQLFQDEVAKAQQLREEQQRQQQQMEQER 2682
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
+ L+ + +E+A + E E+ + + E+ QQ+E+ + EE Q+L
Sbjct: 2683 QRLVAS---MEEARRRQHEAEEGVRRKQEEL-------QQLEQQRRQQEELLAEENQRLR 2732
Query: 409 EAQQSADENNR 441
E Q +E +R
Sbjct: 2733 EQLQLLEEQHR 2743
Score = 36.7 bits (81), Expect = 0.084
Identities = 46/214 (21%), Positives = 91/214 (42%), Gaps = 12/214 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
Q A M+ KK + +K + T Q + + + ++EE++ L+ + +
Sbjct: 2298 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2357
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL-----NRKVQQIEEDLEKSEE----- 378
+ +L +EE K EAE AL + + ++E+ EK ++
Sbjct: 2358 RQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2417
Query: 379 -RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK-EARLLAEDADGKS 552
R A Q+ +Q A+E+ + L + +++ + Q +LK EA LL + + +
Sbjct: 2418 ARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LA 2476
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 654
E +R+L ED+ ++A+ + LE E
Sbjct: 2477 QEQARRLQ--EDKEQMAQQLAEETQGFQRTLEAE 2508
Score = 35.1 bits (77), Expect = 0.26
Identities = 39/224 (17%), Positives = 97/224 (43%), Gaps = 2/224 (0%)
Frame = +1
Query: 58 AATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL 237
AA +A +++ A++ E + K + + A + + + +E +K Q EE
Sbjct: 2132 AAEEEAARQRKAALE-EVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKA 2190
Query: 238 --ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 411
+ K ++ + L++++ L E A R ++ EE ++E + +++++ E
Sbjct: 2191 HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEE 2250
Query: 412 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 591
A++ + +AQ E++ + Q R AE A + + + A +E
Sbjct: 2251 AERLKQSAEEQAQA-RAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAAD--AEMEKH 2307
Query: 592 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ AE ++ +++E+EL + L+ + + ++ ++
Sbjct: 2308 KKFAEQTLRQK----AQVEQELTTLRLQLEETDHQKNLLDEELQ 2347
>AY480046-1|AAR95679.1| 4525|Homo sapiens plectin 3 protein.
Length = 4525
Score = 56.0 bits (129), Expect = 1e-07
Identities = 49/204 (24%), Positives = 94/204 (46%), Gaps = 2/204 (0%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
+ NA D + EQ +A + + EE R ++ +V++ L + Q LEE
Sbjct: 1930 RSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 1989
Query: 289 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV--LEN 462
E+ +A+V R ++ E++ + + + A QK L+A++ A K L+
Sbjct: 1990 ER----LKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 2045
Query: 463 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE 642
QQ++ +DQL + + AR AE+A+ + R+ A ++E AE R+K + ++
Sbjct: 2046 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE-RLKQSAEEQAQ 2104
Query: 643 LEEELKVVGNSLKSLEVSEEKANQ 714
+ + L+ E +E A +
Sbjct: 2105 ARAQAQAAAEKLRK-EAEQEAARR 2127
Score = 49.2 bits (112), Expect = 1e-05
Identities = 48/229 (20%), Positives = 110/229 (48%), Gaps = 10/229 (4%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNA-MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE---E 231
T++A +++ M E + + A+ QAR A A++ ++ E+ +KL + E +
Sbjct: 2345 TLEAERQRQLEMSAEAERLKLRVAEMSRAQAR-AEEDAQRFRKQAEEIGEKLHRTELATQ 2403
Query: 232 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTAQQKLL 408
+ + LE + + ++L AE+ K+QQ + L+ KSEE Q++LL
Sbjct: 2404 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLL 2463
Query: 409 EAQQSADEN--NRMCKVLENRA--QQDEERMDQL-TNQLKEARLLAEDADGKSDEVSRKL 573
+ Q+ ++ + +L+ +Q++ +++QL +++ +A+ L E+ + ++ ++
Sbjct: 2464 QETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQER 2523
Query: 574 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ +E A R + + +EEL+ + + E + NQR+
Sbjct: 2524 QRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRL 2572
Score = 48.0 bits (109), Expect = 3e-05
Identities = 54/223 (24%), Positives = 104/223 (46%), Gaps = 12/223 (5%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKK---LAQVEEDLILNKN 252
++ + +++ + A A+ E Q++ A+ AEK + R LQ++ +AQ+ E+
Sbjct: 1536 ERARQVQVALETAQRSAEA-ELQSKRASF-AEKTAQLERSLQEEHVAVAQLREEAERRAQ 1593
Query: 253 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 432
+ +A + EE E++L + + R Q EE ++ A+++ EA++ A
Sbjct: 1594 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARR 1653
Query: 433 NNRMCK-VLENR--AQQDEERMDQLTNQLKEARLLAED------ADGKSDEVSRKLAFVE 585
+ + + R A+Q+ E+ QL + RL AE A+ + E R+L +E
Sbjct: 1654 RGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQL--LE 1711
Query: 586 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
+EL + + K ELE EL V ++ L S+ +A +
Sbjct: 1712 EELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEE 1754
Score = 44.8 bits (101), Expect = 3e-04
Identities = 47/206 (22%), Positives = 81/206 (39%), Gaps = 3/206 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN-EEVRELQKKL--A 219
Q + +K + +A + EK A+ + QA +A R + E R++Q L A
Sbjct: 1490 QAEVELASRVKAEAEAAR-EKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETA 1548
Query: 220 QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 399
Q + L + A K + E+ L VA L + ++ + ++E A++
Sbjct: 1549 QRSAEAELQSKRASFAEKTAQ-LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAER 1607
Query: 400 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 579
+L Q A+E R+ E AQQ + Q +EA A ++ R+
Sbjct: 1608 ELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQREL 1667
Query: 580 VEDELEVAEDRVKSGDAKISELEEEL 657
E ELE + + E+EL
Sbjct: 1668 AEQELEKQRQLAEGTAQQRLAAEQEL 1693
Score = 39.9 bits (89), Expect = 0.009
Identities = 55/229 (24%), Positives = 98/229 (42%), Gaps = 6/229 (2%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKA-DTCEQQARDANLRAEKVNEEVRELQKKLAQV 225
Q+ A + ++ +M+ + K A +++ T E+ + A + E E + A
Sbjct: 1729 QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALA 1788
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
EE + E A + E E+ L A + R + E L K +E ++L
Sbjct: 1789 EEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL-KEKEAENERLRRL 1847
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
A+ A + R+ + EER+ QL + ++ L E G ++ R+ VE
Sbjct: 1848 --AEDEAFQRRRLEEQAAQHKADIEERLAQL-RKASDSEL--ERQKGLVEDTLRQRRQVE 1902
Query: 586 DELEVAEDRVKSGDAKISELEEEL-KVVGN---SLKSLEVSE-EKANQR 717
+E+ + + A +ELE EL ++ N +L+S E +E E A QR
Sbjct: 1903 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQR 1951
Score = 37.5 bits (83), Expect = 0.048
Identities = 33/147 (22%), Positives = 71/147 (48%), Gaps = 5/147 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQ---ARDANLRAEKVNEEVRELQKKLA 219
QQ+A + ++MQ ++ E+ + + +Q +D+ L+ E+ E+ + KL
Sbjct: 2441 QQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQEKA---KLE 2495
Query: 220 QVEEDLILNKNKL-EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTA 393
Q+ +D + +L E+ + ++ E++ A + R+ + EE + K EE
Sbjct: 2496 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2555
Query: 394 QQKLLEAQQSADENNRMCKVLENRAQQ 474
QQ+ + + A+EN R+ + L+ +Q
Sbjct: 2556 QQRRQQEELLAEENQRLREQLQLLEEQ 2582
Score = 37.1 bits (82), Expect = 0.064
Identities = 30/131 (22%), Positives = 63/131 (48%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+ +A + +K ++ E+ +KA EQ +D +A+++ EE + Q+++ Q
Sbjct: 2465 ETQALQQSFLSEKDSLLQRERFIEQEKAKL-EQLFQDEVAKAQQLREEQQRQQQQMEQER 2523
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
+ L+ + +E+A + E E+ + + E+ QQ+E+ + EE Q+L
Sbjct: 2524 QRLVAS---MEEARRRQHEAEEGVRRKQEEL-------QQLEQQRRQQEELLAEENQRLR 2573
Query: 409 EAQQSADENNR 441
E Q +E +R
Sbjct: 2574 EQLQLLEEQHR 2584
Score = 36.7 bits (81), Expect = 0.084
Identities = 46/214 (21%), Positives = 91/214 (42%), Gaps = 12/214 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
Q A M+ KK + +K + T Q + + + ++EE++ L+ + +
Sbjct: 2139 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2198
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL-----NRKVQQIEEDLEKSEE----- 378
+ +L +EE K EAE AL + + ++E+ EK ++
Sbjct: 2199 RQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2258
Query: 379 -RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK-EARLLAEDADGKS 552
R A Q+ +Q A+E+ + L + +++ + Q +LK EA LL + + +
Sbjct: 2259 ARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LA 2317
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 654
E +R+L ED+ ++A+ + LE E
Sbjct: 2318 QEQARRLQ--EDKEQMAQQLAEETQGFQRTLEAE 2349
Score = 35.1 bits (77), Expect = 0.26
Identities = 39/224 (17%), Positives = 97/224 (43%), Gaps = 2/224 (0%)
Frame = +1
Query: 58 AATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL 237
AA +A +++ A++ E + K + + A + + + +E +K Q EE
Sbjct: 1973 AAEEEAARQRKAALE-EVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKA 2031
Query: 238 --ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 411
+ K ++ + L++++ L E A R ++ EE ++E + +++++ E
Sbjct: 2032 HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEE 2091
Query: 412 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 591
A++ + +AQ E++ + Q R AE A + + + A +E
Sbjct: 2092 AERLKQSAEEQAQA-RAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAAD--AEMEKH 2148
Query: 592 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ AE ++ +++E+EL + L+ + + ++ ++
Sbjct: 2149 KKFAEQTLRQK----AQVEQELTTLRLQLEETDHQKNLLDEELQ 2188
>AY480045-1|AAR95678.1| 4533|Homo sapiens plectin 2 protein.
Length = 4533
Score = 56.0 bits (129), Expect = 1e-07
Identities = 49/204 (24%), Positives = 94/204 (46%), Gaps = 2/204 (0%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
+ NA D + EQ +A + + EE R ++ +V++ L + Q LEE
Sbjct: 1938 RSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 1997
Query: 289 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV--LEN 462
E+ +A+V R ++ E++ + + + A QK L+A++ A K L+
Sbjct: 1998 ER----LKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 2053
Query: 463 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE 642
QQ++ +DQL + + AR AE+A+ + R+ A ++E AE R+K + ++
Sbjct: 2054 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE-RLKQSAEEQAQ 2112
Query: 643 LEEELKVVGNSLKSLEVSEEKANQ 714
+ + L+ E +E A +
Sbjct: 2113 ARAQAQAAAEKLRK-EAEQEAARR 2135
Score = 49.2 bits (112), Expect = 1e-05
Identities = 48/229 (20%), Positives = 110/229 (48%), Gaps = 10/229 (4%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNA-MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE---E 231
T++A +++ M E + + A+ QAR A A++ ++ E+ +KL + E +
Sbjct: 2353 TLEAERQRQLEMSAEAERLKLRVAEMSRAQAR-AEEDAQRFRKQAEEIGEKLHRTELATQ 2411
Query: 232 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTAQQKLL 408
+ + LE + + ++L AE+ K+QQ + L+ KSEE Q++LL
Sbjct: 2412 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLL 2471
Query: 409 EAQQSADEN--NRMCKVLENRA--QQDEERMDQL-TNQLKEARLLAEDADGKSDEVSRKL 573
+ Q+ ++ + +L+ +Q++ +++QL +++ +A+ L E+ + ++ ++
Sbjct: 2472 QETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQER 2531
Query: 574 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ +E A R + + +EEL+ + + E + NQR+
Sbjct: 2532 QRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRL 2580
Score = 48.0 bits (109), Expect = 3e-05
Identities = 54/223 (24%), Positives = 104/223 (46%), Gaps = 12/223 (5%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKK---LAQVEEDLILNKN 252
++ + +++ + A A+ E Q++ A+ AEK + R LQ++ +AQ+ E+
Sbjct: 1544 ERARQVQVALETAQRSAEA-ELQSKRASF-AEKTAQLERSLQEEHVAVAQLREEAERRAQ 1601
Query: 253 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 432
+ +A + EE E++L + + R Q EE ++ A+++ EA++ A
Sbjct: 1602 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARR 1661
Query: 433 NNRMCK-VLENR--AQQDEERMDQLTNQLKEARLLAED------ADGKSDEVSRKLAFVE 585
+ + + R A+Q+ E+ QL + RL AE A+ + E R+L +E
Sbjct: 1662 RGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQL--LE 1719
Query: 586 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
+EL + + K ELE EL V ++ L S+ +A +
Sbjct: 1720 EELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEE 1762
Score = 44.8 bits (101), Expect = 3e-04
Identities = 47/206 (22%), Positives = 81/206 (39%), Gaps = 3/206 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN-EEVRELQKKL--A 219
Q + +K + +A + EK A+ + QA +A R + E R++Q L A
Sbjct: 1498 QAEVELASRVKAEAEAAR-EKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETA 1556
Query: 220 QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 399
Q + L + A K + E+ L VA L + ++ + ++E A++
Sbjct: 1557 QRSAEAELQSKRASFAEKTAQ-LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAER 1615
Query: 400 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 579
+L Q A+E R+ E AQQ + Q +EA A ++ R+
Sbjct: 1616 ELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQREL 1675
Query: 580 VEDELEVAEDRVKSGDAKISELEEEL 657
E ELE + + E+EL
Sbjct: 1676 AEQELEKQRQLAEGTAQQRLAAEQEL 1701
Score = 39.9 bits (89), Expect = 0.009
Identities = 55/229 (24%), Positives = 98/229 (42%), Gaps = 6/229 (2%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKA-DTCEQQARDANLRAEKVNEEVRELQKKLAQV 225
Q+ A + ++ +M+ + K A +++ T E+ + A + E E + A
Sbjct: 1737 QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALA 1796
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
EE + E A + E E+ L A + R + E L K +E ++L
Sbjct: 1797 EEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL-KEKEAENERLRRL 1855
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
A+ A + R+ + EER+ QL + ++ L E G ++ R+ VE
Sbjct: 1856 --AEDEAFQRRRLEEQAAQHKADIEERLAQL-RKASDSEL--ERQKGLVEDTLRQRRQVE 1910
Query: 586 DELEVAEDRVKSGDAKISELEEEL-KVVGN---SLKSLEVSE-EKANQR 717
+E+ + + A +ELE EL ++ N +L+S E +E E A QR
Sbjct: 1911 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQR 1959
Score = 37.5 bits (83), Expect = 0.048
Identities = 33/147 (22%), Positives = 71/147 (48%), Gaps = 5/147 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQ---ARDANLRAEKVNEEVRELQKKLA 219
QQ+A + ++MQ ++ E+ + + +Q +D+ L+ E+ E+ + KL
Sbjct: 2449 QQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQEKA---KLE 2503
Query: 220 QVEEDLILNKNKL-EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTA 393
Q+ +D + +L E+ + ++ E++ A + R+ + EE + K EE
Sbjct: 2504 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2563
Query: 394 QQKLLEAQQSADENNRMCKVLENRAQQ 474
QQ+ + + A+EN R+ + L+ +Q
Sbjct: 2564 QQRRQQEELLAEENQRLREQLQLLEEQ 2590
Score = 37.1 bits (82), Expect = 0.064
Identities = 30/131 (22%), Positives = 63/131 (48%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+ +A + +K ++ E+ +KA EQ +D +A+++ EE + Q+++ Q
Sbjct: 2473 ETQALQQSFLSEKDSLLQRERFIEQEKAKL-EQLFQDEVAKAQQLREEQQRQQQQMEQER 2531
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
+ L+ + +E+A + E E+ + + E+ QQ+E+ + EE Q+L
Sbjct: 2532 QRLVAS---MEEARRRQHEAEEGVRRKQEEL-------QQLEQQRRQQEELLAEENQRLR 2581
Query: 409 EAQQSADENNR 441
E Q +E +R
Sbjct: 2582 EQLQLLEEQHR 2592
Score = 36.7 bits (81), Expect = 0.084
Identities = 46/214 (21%), Positives = 91/214 (42%), Gaps = 12/214 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
Q A M+ KK + +K + T Q + + + ++EE++ L+ + +
Sbjct: 2147 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2206
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL-----NRKVQQIEEDLEKSEE----- 378
+ +L +EE K EAE AL + + ++E+ EK ++
Sbjct: 2207 RQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2266
Query: 379 -RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK-EARLLAEDADGKS 552
R A Q+ +Q A+E+ + L + +++ + Q +LK EA LL + + +
Sbjct: 2267 ARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LA 2325
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 654
E +R+L ED+ ++A+ + LE E
Sbjct: 2326 QEQARRLQ--EDKEQMAQQLAEETQGFQRTLEAE 2357
Score = 35.1 bits (77), Expect = 0.26
Identities = 39/224 (17%), Positives = 97/224 (43%), Gaps = 2/224 (0%)
Frame = +1
Query: 58 AATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL 237
AA +A +++ A++ E + K + + A + + + +E +K Q EE
Sbjct: 1981 AAEEEAARQRKAALE-EVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKA 2039
Query: 238 --ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 411
+ K ++ + L++++ L E A R ++ EE ++E + +++++ E
Sbjct: 2040 HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEE 2099
Query: 412 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 591
A++ + +AQ E++ + Q R AE A + + + A +E
Sbjct: 2100 AERLKQSAEEQAQA-RAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAAD--AEMEKH 2156
Query: 592 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ AE ++ +++E+EL + L+ + + ++ ++
Sbjct: 2157 KKFAEQTLRQK----AQVEQELTTLRLQLEETDHQKNLLDEELQ 2196
>AY480044-1|AAR95677.1| 4574|Homo sapiens plectin 1 protein.
Length = 4574
Score = 56.0 bits (129), Expect = 1e-07
Identities = 49/204 (24%), Positives = 94/204 (46%), Gaps = 2/204 (0%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
+ NA D + EQ +A + + EE R ++ +V++ L + Q LEE
Sbjct: 1979 RSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 2038
Query: 289 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV--LEN 462
E+ +A+V R ++ E++ + + + A QK L+A++ A K L+
Sbjct: 2039 ER----LKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 2094
Query: 463 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE 642
QQ++ +DQL + + AR AE+A+ + R+ A ++E AE R+K + ++
Sbjct: 2095 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE-RLKQSAEEQAQ 2153
Query: 643 LEEELKVVGNSLKSLEVSEEKANQ 714
+ + L+ E +E A +
Sbjct: 2154 ARAQAQAAAEKLRK-EAEQEAARR 2176
Score = 49.2 bits (112), Expect = 1e-05
Identities = 48/229 (20%), Positives = 110/229 (48%), Gaps = 10/229 (4%)
Frame = +1
Query: 64 TMDAIKKKMQAMKLEKDNA-MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE---E 231
T++A +++ M E + + A+ QAR A A++ ++ E+ +KL + E +
Sbjct: 2394 TLEAERQRQLEMSAEAERLKLRVAEMSRAQAR-AEEDAQRFRKQAEEIGEKLHRTELATQ 2452
Query: 232 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTAQQKLL 408
+ + LE + + ++L AE+ K+QQ + L+ KSEE Q++LL
Sbjct: 2453 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLL 2512
Query: 409 EAQQSADEN--NRMCKVLENRA--QQDEERMDQL-TNQLKEARLLAEDADGKSDEVSRKL 573
+ Q+ ++ + +L+ +Q++ +++QL +++ +A+ L E+ + ++ ++
Sbjct: 2513 QETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQER 2572
Query: 574 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ +E A R + + +EEL+ + + E + NQR+
Sbjct: 2573 QRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRL 2621
Score = 48.0 bits (109), Expect = 3e-05
Identities = 54/223 (24%), Positives = 104/223 (46%), Gaps = 12/223 (5%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKK---LAQVEEDLILNKN 252
++ + +++ + A A+ E Q++ A+ AEK + R LQ++ +AQ+ E+
Sbjct: 1585 ERARQVQVALETAQRSAEA-ELQSKRASF-AEKTAQLERSLQEEHVAVAQLREEAERRAQ 1642
Query: 253 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 432
+ +A + EE E++L + + R Q EE ++ A+++ EA++ A
Sbjct: 1643 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARR 1702
Query: 433 NNRMCK-VLENR--AQQDEERMDQLTNQLKEARLLAED------ADGKSDEVSRKLAFVE 585
+ + + R A+Q+ E+ QL + RL AE A+ + E R+L +E
Sbjct: 1703 RGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQL--LE 1760
Query: 586 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
+EL + + K ELE EL V ++ L S+ +A +
Sbjct: 1761 EELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEE 1803
Score = 44.8 bits (101), Expect = 3e-04
Identities = 47/206 (22%), Positives = 81/206 (39%), Gaps = 3/206 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN-EEVRELQKKL--A 219
Q + +K + +A + EK A+ + QA +A R + E R++Q L A
Sbjct: 1539 QAEVELASRVKAEAEAAR-EKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETA 1597
Query: 220 QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 399
Q + L + A K + E+ L VA L + ++ + ++E A++
Sbjct: 1598 QRSAEAELQSKRASFAEKTAQ-LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAER 1656
Query: 400 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 579
+L Q A+E R+ E AQQ + Q +EA A ++ R+
Sbjct: 1657 ELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQREL 1716
Query: 580 VEDELEVAEDRVKSGDAKISELEEEL 657
E ELE + + E+EL
Sbjct: 1717 AEQELEKQRQLAEGTAQQRLAAEQEL 1742
Score = 39.9 bits (89), Expect = 0.009
Identities = 55/229 (24%), Positives = 98/229 (42%), Gaps = 6/229 (2%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKA-DTCEQQARDANLRAEKVNEEVRELQKKLAQV 225
Q+ A + ++ +M+ + K A +++ T E+ + A + E E + A
Sbjct: 1778 QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALA 1837
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
EE + E A + E E+ L A + R + E L K +E ++L
Sbjct: 1838 EEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL-KEKEAENERLRRL 1896
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
A+ A + R+ + EER+ QL + ++ L E G ++ R+ VE
Sbjct: 1897 --AEDEAFQRRRLEEQAAQHKADIEERLAQL-RKASDSEL--ERQKGLVEDTLRQRRQVE 1951
Query: 586 DELEVAEDRVKSGDAKISELEEEL-KVVGN---SLKSLEVSE-EKANQR 717
+E+ + + A +ELE EL ++ N +L+S E +E E A QR
Sbjct: 1952 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQR 2000
Score = 37.5 bits (83), Expect = 0.048
Identities = 33/147 (22%), Positives = 71/147 (48%), Gaps = 5/147 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQ---ARDANLRAEKVNEEVRELQKKLA 219
QQ+A + ++MQ ++ E+ + + +Q +D+ L+ E+ E+ + KL
Sbjct: 2490 QQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQEKA---KLE 2544
Query: 220 QVEEDLILNKNKL-EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTA 393
Q+ +D + +L E+ + ++ E++ A + R+ + EE + K EE
Sbjct: 2545 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2604
Query: 394 QQKLLEAQQSADENNRMCKVLENRAQQ 474
QQ+ + + A+EN R+ + L+ +Q
Sbjct: 2605 QQRRQQEELLAEENQRLREQLQLLEEQ 2631
Score = 37.1 bits (82), Expect = 0.064
Identities = 30/131 (22%), Positives = 63/131 (48%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+ +A + +K ++ E+ +KA EQ +D +A+++ EE + Q+++ Q
Sbjct: 2514 ETQALQQSFLSEKDSLLQRERFIEQEKAKL-EQLFQDEVAKAQQLREEQQRQQQQMEQER 2572
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
+ L+ + +E+A + E E+ + + E+ QQ+E+ + EE Q+L
Sbjct: 2573 QRLVAS---MEEARRRQHEAEEGVRRKQEEL-------QQLEQQRRQQEELLAEENQRLR 2622
Query: 409 EAQQSADENNR 441
E Q +E +R
Sbjct: 2623 EQLQLLEEQHR 2633
Score = 36.7 bits (81), Expect = 0.084
Identities = 46/214 (21%), Positives = 91/214 (42%), Gaps = 12/214 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
Q A M+ KK + +K + T Q + + + ++EE++ L+ + +
Sbjct: 2188 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2247
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL-----NRKVQQIEEDLEKSEE----- 378
+ +L +EE K EAE AL + + ++E+ EK ++
Sbjct: 2248 RQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2307
Query: 379 -RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK-EARLLAEDADGKS 552
R A Q+ +Q A+E+ + L + +++ + Q +LK EA LL + + +
Sbjct: 2308 ARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LA 2366
Query: 553 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 654
E +R+L ED+ ++A+ + LE E
Sbjct: 2367 QEQARRLQ--EDKEQMAQQLAEETQGFQRTLEAE 2398
Score = 35.1 bits (77), Expect = 0.26
Identities = 39/224 (17%), Positives = 97/224 (43%), Gaps = 2/224 (0%)
Frame = +1
Query: 58 AATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL 237
AA +A +++ A++ E + K + + A + + + +E +K Q EE
Sbjct: 2022 AAEEEAARQRKAALE-EVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKA 2080
Query: 238 --ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 411
+ K ++ + L++++ L E A R ++ EE ++E + +++++ E
Sbjct: 2081 HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEE 2140
Query: 412 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 591
A++ + +AQ E++ + Q R AE A + + + A +E
Sbjct: 2141 AERLKQSAEEQAQA-RAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAAD--AEMEKH 2197
Query: 592 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ AE ++ +++E+EL + L+ + + ++ ++
Sbjct: 2198 KKFAEQTLRQK----AQVEQELTTLRLQLEETDHQKNLLDEELQ 2237
>AF362887-1|AAK51964.1| 142|Homo sapiens tropomyosin 4-anaplastic
lymphoma kinase fusion protein minor isoform protein.
Length = 142
Score = 56.0 bits (129), Expect = 1e-07
Identities = 30/113 (26%), Positives = 66/113 (58%), Gaps = 3/113 (2%)
Frame = +1
Query: 271 KDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 450
+++E + + EAEVA+LNR++Q +EE+L++++ER+ ++ K + ++ K
Sbjct: 1 REVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERAEVSELKCGDLEEELKNVTNNLK 60
Query: 451 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE---DELEV 600
LE +++ E+ D+ ++K ++A+ +++ R +A +E D+LEV
Sbjct: 61 SLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEV 113
Score = 55.6 bits (128), Expect = 2e-07
Identities = 26/71 (36%), Positives = 47/71 (66%)
Frame = +1
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 684
+++ R E A+ + ++R++ VE+EL+ A++R + + K +LEEELK V N+LKS
Sbjct: 2 EVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERAEVSELKCGDLEEELKNVTNNLKS 61
Query: 685 LEVSEEKANQR 717
LE + EK +++
Sbjct: 62 LEAASEKYSEK 72
>AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein.
Length = 1870
Score = 56.0 bits (129), Expect = 1e-07
Identities = 56/217 (25%), Positives = 105/217 (48%), Gaps = 18/217 (8%)
Frame = +1
Query: 64 TMDAIKK-KMQAMKLEKDNAMDKADTCE-----QQARDANLRAEKVNEEVRELQKKLAQV 225
T+D+ K Q LEK+N+ + E + + A+++ ++ E +EL+ + Q+
Sbjct: 678 TLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQL 737
Query: 226 EEDLILNK------NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 387
++ L L K +LE + + L+ + ++L T + N+K+QQ+E +L+ E +
Sbjct: 738 KKGLELLKASFKKTERLEVSYQGLDIENQRLQKT---LENSNKKIQQLESELQDLEMENQ 794
Query: 388 TAQQKLLEAQQSA---DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE 558
T Q+ L E + S+ ++ + K LE Q E+ QL + K R AE D +E
Sbjct: 795 TLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEE 854
Query: 559 VSRKLAFVEDELEVAEDRV---KSGDAKISELEEELK 660
+ K+ +E E + + K ++ ELE+E K
Sbjct: 855 NNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENK 891
Score = 48.4 bits (110), Expect = 3e-05
Identities = 36/215 (16%), Positives = 104/215 (48%), Gaps = 3/215 (1%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE---EDLI 240
+ +KK ++ +K + K + E + ++ +++ + + KK+ Q+E +DL
Sbjct: 735 EQLKKGLELLKA----SFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLE 790
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
+ L++ ++L+ K+L E E +L ++ Q+E+D ++ E+ + +Q+
Sbjct: 791 MENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDT 850
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
+ +ENN V +++ + + + KE+ + ++ + ++ E+ ++ L
Sbjct: 851 TLEENN----VKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVT 906
Query: 601 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+ + S K ++ +L+ + + L+ + +++E+
Sbjct: 907 LREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKER 941
Score = 41.1 bits (92), Expect = 0.004
Identities = 46/203 (22%), Positives = 93/203 (45%), Gaps = 24/203 (11%)
Frame = +1
Query: 154 RDANLRAEKVNEEVRELQKK-------LAQVEEDLILNKNKLEQANKDLEE--------- 285
+++ +R +++ +E +EL K+ L + EDL+ K K +Q N DLE+
Sbjct: 877 KESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIG 936
Query: 286 --KEKQL---TATEAEVAALNRKVQQ-IEEDLEKSEERSGTAQQKLLEAQQSADENNRMC 447
KE+ L +T+ L K++ +++ LE EE+ + +L E+ + +
Sbjct: 937 LNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQEL 996
Query: 448 KVLENRAQQDEERMDQLTNQLKEARLLAEDA--DGKSDEVSRKLAFVEDELEVAEDRVKS 621
K ++ + ++R D+ + ED + +S E +R+L V+D L E +
Sbjct: 997 KTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNAT 1056
Query: 622 GDAKISELEEELKVVGNSLKSLE 690
A+ L+ +LK + +L+
Sbjct: 1057 LQAEKQALKTQLKQLETQNNNLQ 1079
Score = 39.5 bits (88), Expect = 0.012
Identities = 46/246 (18%), Positives = 110/246 (44%), Gaps = 24/246 (9%)
Frame = +1
Query: 49 QQKAATMDAIK-KKMQAMKLEKDNAM--DKADTCEQQARDANLRAEKVNEEVRELQKKLA 219
++ T+D+++ + +K+EK+N K + E + + ++L K+ A
Sbjct: 477 EELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKA 536
Query: 220 QVEEDL-ILNKNK------LEQANKDLEE-----KEKQLTATEAEVAALNRKVQQIEEDL 363
Q+E+ + L +N LEQ N+ L + +++ + EA V + ++ + + E +
Sbjct: 537 QLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESI 596
Query: 364 EKSEERSGTAQQKLLEAQQSAD---ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 534
+++ + + + + ++ + E + LEN E+ + L ++ ++ E
Sbjct: 597 KETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCE 656
Query: 535 DADGKSDEVS------RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVS 696
+ E S RKL D + +++S + + S+L+EE + +++SL+ +
Sbjct: 657 KIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCA 716
Query: 697 EEKANQ 714
K Q
Sbjct: 717 SMKMAQ 722
Score = 30.7 bits (66), Expect = 5.5
Identities = 42/220 (19%), Positives = 95/220 (43%), Gaps = 9/220 (4%)
Frame = +1
Query: 91 QAMKLEKDNAMDKADTCEQQARDANL-----RAEKVNEEVRELQKKLAQVEEDLILNKNK 255
Q KL+ +N+ + + ++A L E NE V + ++ L + + LI + K
Sbjct: 1102 QNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEK 1161
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
LE ++ + + L + + + ++ ++ DLE +LL+ + ++
Sbjct: 1162 LELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLE-------DRYNQLLKQKGQLEDL 1214
Query: 436 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 615
+M KV + + + + + + + K+ L + D + S+ L E L+ +
Sbjct: 1215 EKMLKVEQEKMLLENKNHETVAAEYKK---LCGENDRLNHTYSQLLKETE-VLQTDHKNL 1270
Query: 616 KS--GDAKISE--LEEELKVVGNSLKSLEVSEEKANQRVE 723
KS ++K+ + LE E + + L+++ K N + E
Sbjct: 1271 KSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCE 1310
>AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein
protein.
Length = 1843
Score = 56.0 bits (129), Expect = 1e-07
Identities = 56/217 (25%), Positives = 105/217 (48%), Gaps = 18/217 (8%)
Frame = +1
Query: 64 TMDAIKK-KMQAMKLEKDNAMDKADTCE-----QQARDANLRAEKVNEEVRELQKKLAQV 225
T+D+ K Q LEK+N+ + E + + A+++ ++ E +EL+ + Q+
Sbjct: 678 TLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQL 737
Query: 226 EEDLILNK------NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 387
++ L L K +LE + + L+ + ++L T + N+K+QQ+E +L+ E +
Sbjct: 738 KKGLELLKASFKKTERLEVSYQGLDIENQRLQKT---LENSNKKIQQLESELQDLEMENQ 794
Query: 388 TAQQKLLEAQQSA---DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE 558
T Q+ L E + S+ ++ + K LE Q E+ QL + K R AE D +E
Sbjct: 795 TLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEE 854
Query: 559 VSRKLAFVEDELEVAEDRV---KSGDAKISELEEELK 660
+ K+ +E E + + K ++ ELE+E K
Sbjct: 855 NNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENK 891
Score = 48.4 bits (110), Expect = 3e-05
Identities = 36/215 (16%), Positives = 104/215 (48%), Gaps = 3/215 (1%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE---EDLI 240
+ +KK ++ +K + K + E + ++ +++ + + KK+ Q+E +DL
Sbjct: 735 EQLKKGLELLKA----SFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLE 790
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
+ L++ ++L+ K+L E E +L ++ Q+E+D ++ E+ + +Q+
Sbjct: 791 MENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDT 850
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
+ +ENN V +++ + + + KE+ + ++ + ++ E+ ++ L
Sbjct: 851 TLEENN----VKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVT 906
Query: 601 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+ + S K ++ +L+ + + L+ + +++E+
Sbjct: 907 LREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKER 941
Score = 39.5 bits (88), Expect = 0.012
Identities = 46/246 (18%), Positives = 110/246 (44%), Gaps = 24/246 (9%)
Frame = +1
Query: 49 QQKAATMDAIK-KKMQAMKLEKDNAM--DKADTCEQQARDANLRAEKVNEEVRELQKKLA 219
++ T+D+++ + +K+EK+N K + E + + ++L K+ A
Sbjct: 477 EELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKA 536
Query: 220 QVEEDL-ILNKNK------LEQANKDLEE-----KEKQLTATEAEVAALNRKVQQIEEDL 363
Q+E+ + L +N LEQ N+ L + +++ + EA V + ++ + + E +
Sbjct: 537 QLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESI 596
Query: 364 EKSEERSGTAQQKLLEAQQSAD---ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 534
+++ + + + + ++ + E + LEN E+ + L ++ ++ E
Sbjct: 597 KETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCE 656
Query: 535 DADGKSDEVS------RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVS 696
+ E S RKL D + +++S + + S+L+EE + +++SL+ +
Sbjct: 657 KIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCA 716
Query: 697 EEKANQ 714
K Q
Sbjct: 717 SMKMAQ 722
Score = 30.7 bits (66), Expect = 5.5
Identities = 42/220 (19%), Positives = 95/220 (43%), Gaps = 9/220 (4%)
Frame = +1
Query: 91 QAMKLEKDNAMDKADTCEQQARDANL-----RAEKVNEEVRELQKKLAQVEEDLILNKNK 255
Q KL+ +N+ + + ++A L E NE V + ++ L + + LI + K
Sbjct: 1103 QNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEK 1162
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
LE ++ + + L + + + ++ ++ DLE +LL+ + ++
Sbjct: 1163 LELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLE-------DRYNQLLKQKGQLEDL 1215
Query: 436 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 615
+M KV + + + + + + + K+ L + D + S+ L E L+ +
Sbjct: 1216 EKMLKVEQEKMLLENKNHETVAAEYKK---LCGENDRLNHTYSQLLKETE-VLQTDHKNL 1271
Query: 616 KS--GDAKISE--LEEELKVVGNSLKSLEVSEEKANQRVE 723
KS ++K+ + LE E + + L+++ K N + E
Sbjct: 1272 KSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCE 1311
>Z75311-1|CAA99729.1| 1318|Homo sapiens RAD50 homologue hsRAD50
protein.
Length = 1318
Score = 55.6 bits (128), Expect = 2e-07
Identities = 42/190 (22%), Positives = 90/190 (47%), Gaps = 1/190 (0%)
Frame = +1
Query: 148 QARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAA 327
Q D + ++VN+E +E Q KL V + LN+ ++ + ++ + ++E
Sbjct: 823 QGIDLDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTNELKSEKLQ 882
Query: 328 LNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQ 507
++ +Q+ ++ E++ E S Q E + + ++ + + LE Q+ EE L N+
Sbjct: 883 ISTNLQRRQQLEEQTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQQEKEE----LINK 938
Query: 508 LKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG-DAKISELEEELKVVGNSLKS 684
+ +A+D K +++ K+ + ++ E+ ++ G D + + E EL V L
Sbjct: 939 KNTSNKIAQD---KLNDIKEKVKNIHGYMKDIENHIQDGKDDYMKQKETELNKVIAQLSE 995
Query: 685 LEVSEEKANQ 714
E +EK N+
Sbjct: 996 CEKHKEKINE 1005
Score = 52.0 bits (119), Expect = 2e-06
Identities = 42/182 (23%), Positives = 90/182 (49%), Gaps = 13/182 (7%)
Frame = +1
Query: 184 NEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL------NRKVQ 345
++E+ + + +LA++ ++L ++ N +LE KE+QL++ E ++ + +
Sbjct: 590 SKEINQTRDRLAKLNKELASSEQNKNHINNELERKEEQLSSYEDKLFDVCGSQDFESDLD 649
Query: 346 QIEEDLEKS-EERSGTAQQKLLEAQ---QSADENNRMCKVLENRAQQDEERMDQLTNQLK 513
+++E++EKS ++R+ A + +Q Q DEN C V + Q + E + +++
Sbjct: 650 RLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEAISDLQS 709
Query: 514 EARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAK---ISELEEELKVVGNSLKS 684
+ RL + E+ +K ++ L +A R D K I EL +L+ V ++
Sbjct: 710 KLRLAPDKLKSTESELKKKEKRRDEMLGLAPMRQSIIDLKEKEIPELRNKLQNVNRDIQR 769
Query: 685 LE 690
L+
Sbjct: 770 LK 771
Score = 43.2 bits (97), Expect = 0.001
Identities = 42/176 (23%), Positives = 86/176 (48%), Gaps = 3/176 (1%)
Frame = +1
Query: 166 LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 345
L +K+ EL+KK + D +L + Q+ DL KEK++ ++ +NR +Q
Sbjct: 713 LAPDKLKSTESELKKK--EKRRDEMLGLAPMRQSIIDL--KEKEIPELRNKLQNVNRDIQ 768
Query: 346 QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 525
+++ D+E+ E GT ++ ++SA ++E R Q + + +++ Q + A+L
Sbjct: 769 RLKNDIEEQETLLGT----IMPEEESAKVCLTDVTIME-RFQMELKDVERKIAQ-QAAKL 822
Query: 526 LAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE---LKVVGNSLKS 684
D D +V+++ + +L+ +++ I + +E+ LK N LKS
Sbjct: 823 QGIDLDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTNELKS 878
Score = 35.5 bits (78), Expect = 0.19
Identities = 36/170 (21%), Positives = 80/170 (47%), Gaps = 3/170 (1%)
Frame = +1
Query: 169 RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTAT---EAEVAALNRK 339
+A ++ +++ + +L +E + +N+L+ L+E E L+ + E+ AL+ +
Sbjct: 225 KACEIRDQITSKEAQLTSSKEIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALDSR 284
Query: 340 VQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA 519
+Q+E+D + EE+ Q E N++ + R D R +L KE+
Sbjct: 285 KKQMEKDNSELEEKMEKVFQGTDEQLNDLYHNHQRTVREKERKLVDCHR--ELEKLNKES 342
Query: 520 RLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVG 669
RLL ++ E R ++ + + ++ +++ D+ I L +L++ G
Sbjct: 343 RLLNQEKSELLVEQGR----LQLQADRHQEHIRARDSLIQSLATQLELDG 388
>X03741-1|CAA27381.1| 635|Homo sapiens protein ( Human cardiac mRNA
for myosin heavy chain light meromyosin region. ).
Length = 635
Score = 55.6 bits (128), Expect = 2e-07
Identities = 40/191 (20%), Positives = 80/191 (41%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 122 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 181
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 182 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 241
Query: 502 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 681
+ L+EA E +GK + +L F + + E+ R + + L+VV +
Sbjct: 242 SALEEAEASLEHEEGKI--LRAQLEFNQIKAEIERKRQEKDEEMEQAKRNHLRVVDSLQT 299
Query: 682 SLEVSEEKANQ 714
SL+ N+
Sbjct: 300 SLDAETRSRNE 310
Score = 53.6 bits (123), Expect = 7e-07
Identities = 57/223 (25%), Positives = 104/223 (46%), Gaps = 9/223 (4%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE--KVNEEVRELQKKLAQ 222
+++ +A+ +Q+ + + D ++ + E+ A L+ + K N EV + + K
Sbjct: 20 EEEVKAKNALAHALQSARHDCDLLREQYE--EETEAKARLQGDLSKANSEVAQWRTKY-- 75
Query: 223 VEEDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEER 381
E D I +LE+A K L +E E+ + A A+ ++L + +++ EDL ER
Sbjct: 76 -ETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVER 134
Query: 382 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 561
S A L + Q++ D K+L Q+ EE +L + KEAR L+ + +
Sbjct: 135 SNAAAAALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAY 188
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
L + LE + K+ +IS+L E+L G ++ LE
Sbjct: 189 EESL----EHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 227
Score = 50.8 bits (116), Expect = 5e-06
Identities = 55/230 (23%), Positives = 112/230 (48%), Gaps = 14/230 (6%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 243
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++K + +E+
Sbjct: 226 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKRQEKDEE--- 282
Query: 244 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 411
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 283 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 338
Query: 412 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 564
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 339 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 398
Query: 565 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
RKLA E EL +RV+ ++ + L + K + L L+ E+A Q
Sbjct: 399 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQ 446
>D86970-1|BAA13206.2| 2067|Homo sapiens KIAA0216 protein.
Length = 2067
Score = 55.6 bits (128), Expect = 2e-07
Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 7/179 (3%)
Frame = +1
Query: 208 KKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI-------EEDLE 366
K A + ++ KN+LE++ K A E E+ L+ ++ I EE L
Sbjct: 1689 KNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLS 1748
Query: 367 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 546
+ + Q +L E Q+ +E + K +A +D +++ L QL+EA ++
Sbjct: 1749 RLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQE 1808
Query: 547 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
K + ++ F+E + V + V +AKI ELE L+ +K LE + + +E
Sbjct: 1809 KLQALQSQVEFLEQSM-VDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENME 1866
Score = 53.6 bits (123), Expect = 7e-07
Identities = 52/242 (21%), Positives = 122/242 (50%), Gaps = 18/242 (7%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++ T A K +AM++E ++ + D + + ++ E E+Q +L + +
Sbjct: 1706 EESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQ 1765
Query: 229 EDL--ILNKNK--LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE------- 375
ED+ ++ K+K + QA++DL Q+ +A++ N++ Q+++E L+ +
Sbjct: 1766 EDMNELMKKHKAAVAQASRDLA----QINDLQAQLEEANKEKQELQEKLQALQSQVEFLE 1821
Query: 376 ----ERSGTAQQ--KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 537
++S ++Q K+ E + + K LE+ A + +E M++LT + ++ R+ AE+
Sbjct: 1822 QSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEE-RDQRIAAEN 1880
Query: 538 ADGKSDE-VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
+ + ++ + R+L ++E+ + K ELE +L+ + + +SL+ + A +
Sbjct: 1881 REKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFK 1940
Query: 715 RV 720
R+
Sbjct: 1941 RI 1942
Score = 45.2 bits (102), Expect = 2e-04
Identities = 42/198 (21%), Positives = 88/198 (44%), Gaps = 5/198 (2%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
QQ + L E+ N+ R+L+++L ++ D ++ L+Q K + +L T+ +
Sbjct: 1403 QQEFEDKLEVEQQNK--RQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLE 1460
Query: 325 ALNRKVQQIEE-----DLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 489
+ ++E+ D E S+ ++KL + +++ + + + Q +E+ M
Sbjct: 1461 GQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDM 1520
Query: 490 DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVG 669
D K L AE D S E E L + +++ +AK+ + EEEL
Sbjct: 1521 DIAGFTQKVVSLEAELQDISSQESKD-----EASLAKVKKQLRDLEAKVKDQEEELDEQA 1575
Query: 670 NSLKSLEVSEEKANQRVE 723
+++ LE ++ + +E
Sbjct: 1576 GTIQMLEQAKLRLEMEME 1593
Score = 41.1 bits (92), Expect = 0.004
Identities = 52/229 (22%), Positives = 101/229 (44%), Gaps = 11/229 (4%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKL---EKDNAMDKADTCEQQARDANLRAEKVNEEVR-----ELQKKL 216
A++ +KK+++ ++ +++ +D+ Q A LR E E +R E++ +
Sbjct: 1548 ASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRD 1607
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 396
+VEE + KL+Q LEE+ + E L K+ + + + + + S
Sbjct: 1608 EEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRL 1667
Query: 397 QKLLEAQQS-ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 573
+K L+ ++ + M L+N A E + QL NQL+E+ A +RK
Sbjct: 1668 RKDLKRTKALLADAQLMLDHLKNSAPSKRE-IAQLKNQLEESEFTCAAA-----VKARKA 1721
Query: 574 AFVE-DELEVAEDRVKSGDAKISELEEELKVVGNSLKS-LEVSEEKANQ 714
VE ++L + D + + E L+ N +++ LE +E N+
Sbjct: 1722 MEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNE 1770
Score = 39.5 bits (88), Expect = 0.012
Identities = 33/141 (23%), Positives = 67/141 (47%), Gaps = 1/141 (0%)
Frame = +1
Query: 148 QARDANLRAE-KVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
+ RD + AE + E+ + LQ++L +E++ E A K+ E K+ E ++
Sbjct: 1870 EERDQRIAAENREKEQNKRLQRQLRDTKEEMG------ELARKEAEASRKK-HELEMDLE 1922
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
+L Q ++ DL+ + +R G Q + E + +DEN + L++ + ++R ++L
Sbjct: 1923 SLEAANQSLQADLKLAFKRIGDLQAAI-EDEMESDENEDLINSLQDMVTKYQKRKNKLEG 1981
Query: 505 QLKEARLLAEDADGKSDEVSR 567
L + DG +S+
Sbjct: 1982 DSDVDSELEDRVDGVKSWLSK 2002
>D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heavy
chain protein.
Length = 1052
Score = 55.6 bits (128), Expect = 2e-07
Identities = 55/249 (22%), Positives = 118/249 (47%), Gaps = 16/249 (6%)
Frame = +1
Query: 25 VFNSTGP*QQKAATMDAIKKKMQ-----AMKLEKDNAMDKADTCEQQARDANLRAEKVNE 189
+F + ++KA +++A ++Q A + K ++K + E+ A + R + +
Sbjct: 785 IFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR-NALQD 843
Query: 190 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 369
E R L+ ++AQ+EE+L + +E + + + +Q E+A Q+ E ++
Sbjct: 844 EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ 903
Query: 370 SEERSGTAQQKLLEAQQSADENNRMC-KVLENRAQQDEERMDQLTNQLKEARLLAEDADG 546
E ++ + KL E + + + LE + Q EE+++Q + + A + D
Sbjct: 904 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 963
Query: 547 KSDEVSRKLAFVEDELEVAE---DRVKSGDAKISEL-------EEELKVVGNSLKSLEVS 696
K E+ L VEDE ++AE ++ + G+A++ +L EEE + + + + L+
Sbjct: 964 KLKEI---LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1020
Query: 697 EEKANQRVE 723
++A + E
Sbjct: 1021 LDEATESNE 1029
Score = 54.0 bits (124), Expect = 5e-07
Identities = 38/200 (19%), Positives = 97/200 (48%), Gaps = 5/200 (2%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 848 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNESA---RQQ 903
Query: 256 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 904 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 963
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 964 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 1023
Query: 601 AEDRVKSGDAKISELEEELK 660
A + ++ +++ L+ +L+
Sbjct: 1024 ATESNEAMGREVNALKSKLR 1043
Score = 51.6 bits (118), Expect = 3e-06
Identities = 38/216 (17%), Positives = 99/216 (45%), Gaps = 15/216 (6%)
Frame = +1
Query: 58 AATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL 237
AA ++ ++ ++L+ D+A+ + +Q R + + E+ + + ++
Sbjct: 730 AAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATA 789
Query: 238 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS-------EERSGTAQ 396
N+ K + DL + ++ L A E + + +++ E+L S ++ +
Sbjct: 790 KENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE 849
Query: 397 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLA 576
++ + ++ +E + + +R ++ ++ +QL+N+L R A+ + ++ R+
Sbjct: 850 ARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNK 909
Query: 577 FVEDELEVAEDRVKSG--------DAKISELEEELK 660
+ +L E VKS +AKI++LEE+++
Sbjct: 910 ELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVE 945
Score = 50.8 bits (116), Expect = 5e-06
Identities = 37/217 (17%), Positives = 92/217 (42%), Gaps = 1/217 (0%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++++ +++ + D M+ E+ N++ +++++ + +EE + +
Sbjct: 455 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 514
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADE 432
+E + EEK E L +++ + DL+ + ++K + Q A+E
Sbjct: 515 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 574
Query: 433 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 612
N K + R + + E ++ T L AR L E + K +E+ R ++ E+E
Sbjct: 575 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSS 633
Query: 613 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ ELE+ + + ++ ++ E+ ++
Sbjct: 634 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQ 670
Score = 46.8 bits (106), Expect = 8e-05
Identities = 45/206 (21%), Positives = 88/206 (42%), Gaps = 1/206 (0%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
K D A T E + R +K E + + ++ A + L KN+L+Q DL
Sbjct: 491 KKKLQDFASTVEA-LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 549
Query: 289 EKQLTATEAEVAALNRKVQQI-EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 465
+ + RK Q+ E+ S + + + EA++ + + + LE
Sbjct: 550 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 609
Query: 466 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
+ EE + TN++ +A + ED D+V + + +E E +++ ++ EL
Sbjct: 610 LEAKEEL--ERTNKMLKAEM--EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 665
Query: 646 EEELKVVGNSLKSLEVSEEKANQRVE 723
E+EL+ ++ LEV+ + + E
Sbjct: 666 EDELQASEDAKLRLEVNMQALKGQFE 691
Score = 42.7 bits (96), Expect = 0.001
Identities = 49/181 (27%), Positives = 88/181 (48%), Gaps = 1/181 (0%)
Frame = +1
Query: 166 LRAE-KVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 342
L+AE ++ E E++ +LA +++L + L + LEE+E + +AE + +++
Sbjct: 10 LQAETELYAEAEEMRVRLAAKKQEL---EEILHEMEARLEEEEDRGQQLQAERKKMAQQM 66
Query: 343 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 522
+EE LE+ E A+QKL + +A+ K LE+ MD N+L + R
Sbjct: 67 LDLEEQLEEEE----AARQKLQLEKVTAEAK---IKKLEDEILV----MDDQNNKLSKER 115
Query: 523 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 702
L E+ + +++ LA E++ + ++ ISELE LK S + LE +
Sbjct: 116 KLLEE---RISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKR 172
Query: 703 K 705
K
Sbjct: 173 K 173
Score = 42.3 bits (95), Expect = 0.002
Identities = 50/235 (21%), Positives = 102/235 (43%), Gaps = 11/235 (4%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADT----CEQQARDANLRAEKVNEEVRELQK-- 210
Q + T +A KK++ L D+ +K E++ D + E+ + L K
Sbjct: 84 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLK 143
Query: 211 -KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAE----VAALNRKVQQIEEDLEKSE 375
K + +L + K E++ ++LE+ +++L ++ +A L ++ +++ L K E
Sbjct: 144 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 203
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
E A +L + + A +NN + K+ E E + L L R A+ +
Sbjct: 204 EELQAALARLDD--EIAQKNNALKKIREL-----EGHISDLQEDLDSERAARNKAEKQKR 256
Query: 556 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
++ +L ++ ELE D + ++ E+E+ V+ +L S E Q +
Sbjct: 257 DLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEM 311
Score = 35.1 bits (77), Expect = 0.26
Identities = 27/100 (27%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++K A ++K+K + +K D+ EQ +AEK N V++L+++L + E
Sbjct: 949 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE----QAEKGNARVKQLKRQLEEAE 1004
Query: 229 ED-LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 345
E+ +N N+ + ++L+E + A EV AL K++
Sbjct: 1005 EESQRINANR-RKLQRELDEATESNEAMGREVNALKSKLR 1043
>BC142716-1|AAI42717.1| 601|Homo sapiens EPS15L1 protein protein.
Length = 601
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/144 (21%), Positives = 68/144 (47%)
Frame = +1
Query: 292 KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 471
K+L E+A L R+ +E+D+ + EE ++ E Q D + LE + Q
Sbjct: 384 KELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQ 443
Query: 472 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE 651
++R+D++ Q + R + D K + ++ ++ ++ +++ E +KS + ++ +
Sbjct: 444 DAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKS 503
Query: 652 ELKVVGNSLKSLEVSEEKANQRVE 723
EL + LE S + ++E
Sbjct: 504 ELNRLQQEETQLEQSIQAGRVQLE 527
>BC142662-1|AAI42663.1| 600|Homo sapiens EPS15L1 protein protein.
Length = 600
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/144 (21%), Positives = 68/144 (47%)
Frame = +1
Query: 292 KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 471
K+L E+A L R+ +E+D+ + EE ++ E Q D + LE + Q
Sbjct: 383 KELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQ 442
Query: 472 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE 651
++R+D++ Q + R + D K + ++ ++ ++ +++ E +KS + ++ +
Sbjct: 443 DAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKS 502
Query: 652 ELKVVGNSLKSLEVSEEKANQRVE 723
EL + LE S + ++E
Sbjct: 503 ELNRLQQEETQLEQSIQAGRVQLE 526
>BC131590-1|AAI31591.1| 754|Homo sapiens EPS15L1 protein protein.
Length = 754
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/144 (21%), Positives = 68/144 (47%)
Frame = +1
Query: 292 KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 471
K+L E+A L R+ +E+D+ + EE ++ E Q D + LE + Q
Sbjct: 384 KELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQ 443
Query: 472 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE 651
++R+D++ Q + R + D K + ++ ++ ++ +++ E +KS + ++ +
Sbjct: 444 DAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKS 503
Query: 652 ELKVVGNSLKSLEVSEEKANQRVE 723
EL + LE S + ++E
Sbjct: 504 ELNRLQQEETQLEQSIQAGRVQLE 527
>BC104912-1|AAI04913.1| 1236|Homo sapiens PPFIA2 protein protein.
Length = 1236
Score = 55.6 bits (128), Expect = 2e-07
Identities = 44/181 (24%), Positives = 82/181 (45%), Gaps = 4/181 (2%)
Frame = +1
Query: 187 EEVRELQK-KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 363
+E+ E Q ++AQ++E L +++ + ++ E K L TE R +++
Sbjct: 274 QELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQK 333
Query: 364 EKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDE---ERMDQLTNQLKEARLLAE 534
E EER T +++ L AQ+ + + M LEN E +M++ QL+E LAE
Sbjct: 334 EDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAE 393
Query: 535 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
++ + L VE EL + + + +EE ++ + L+ ++A Q
Sbjct: 394 QKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQ 453
Query: 715 R 717
R
Sbjct: 454 R 454
Score = 46.8 bits (106), Expect = 8e-05
Identities = 42/165 (25%), Positives = 82/165 (49%), Gaps = 2/165 (1%)
Frame = +1
Query: 103 LEKDNAMDKADTCEQQARDANLRAEKVNEE--VRELQKKLAQVEEDLILNKNKLEQANKD 276
LEK + ++ + L E N+E +R++++K Q++E L L + KL+Q +
Sbjct: 343 LEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMR- 401
Query: 277 LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 456
K + L EAE+A Q+I L K+EER G ++++ + +E N+ +
Sbjct: 402 ---KAETLPEVEAELA------QRIAA-LTKAEERHGNIEERMRHLEGQLEEKNQELQRA 451
Query: 457 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 591
R + +EE +L++ + RLL E + + ++A +E++
Sbjct: 452 RQREKMNEEHNKRLSDTVD--RLLTESNERLQLHLKERMAALEEK 494
Score = 37.9 bits (84), Expect = 0.036
Identities = 40/189 (21%), Positives = 77/189 (40%), Gaps = 13/189 (6%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
M +K+++ A+ +A+T + K ++RE + +EE +
Sbjct: 284 MAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDMEERITTL 343
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+ + A ++ E E+A ++Q+EE + +ER A+QKL + + A
Sbjct: 344 EKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKA 403
Query: 427 DE--------NNRMCKV--LENRAQQDEERMDQLTNQLKEAR---LLAEDADGKSDEVSR 567
+ R+ + E R EERM L QL+E A + ++E ++
Sbjct: 404 ETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNK 463
Query: 568 KLAFVEDEL 594
+L+ D L
Sbjct: 464 RLSDTVDRL 472
>BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 55.6 bits (128), Expect = 2e-07
Identities = 55/249 (22%), Positives = 118/249 (47%), Gaps = 16/249 (6%)
Frame = +1
Query: 25 VFNSTGP*QQKAATMDAIKKKMQ-----AMKLEKDNAMDKADTCEQQARDANLRAEKVNE 189
+F + ++KA +++A ++Q A + K ++K + E+ A + R + +
Sbjct: 1671 IFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR-NALQD 1729
Query: 190 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 369
E R L+ ++AQ+EE+L + +E + + + +Q E+A Q+ E ++
Sbjct: 1730 EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ 1789
Query: 370 SEERSGTAQQKLLEAQQSADENNRMC-KVLENRAQQDEERMDQLTNQLKEARLLAEDADG 546
E ++ + KL E + + + LE + Q EE+++Q + + A + D
Sbjct: 1790 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1849
Query: 547 KSDEVSRKLAFVEDELEVAE---DRVKSGDAKISEL-------EEELKVVGNSLKSLEVS 696
K E+ L VEDE ++AE ++ + G+A++ +L EEE + + + + L+
Sbjct: 1850 KLKEI---LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1906
Query: 697 EEKANQRVE 723
++A + E
Sbjct: 1907 LDEATESNE 1915
Score = 54.0 bits (124), Expect = 5e-07
Identities = 38/200 (19%), Positives = 97/200 (48%), Gaps = 5/200 (2%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 1734 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNESA---RQQ 1789
Query: 256 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 1790 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1849
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 1850 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 1909
Query: 601 AEDRVKSGDAKISELEEELK 660
A + ++ +++ L+ +L+
Sbjct: 1910 ATESNEAMGREVNALKSKLR 1929
Score = 52.0 bits (119), Expect = 2e-06
Identities = 41/223 (18%), Positives = 103/223 (46%), Gaps = 19/223 (8%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 216
+++ A A KKK++ ++L+ D+A+ + +Q R + + E+ + +
Sbjct: 1609 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1668
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS-------E 375
++ N+ K + DL + ++ L A E + + +++ E+L S +
Sbjct: 1669 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ 1728
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
+ + ++ + ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 1729 DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ 1788
Query: 556 EVSRKLAFVEDELEVAEDRVKSG--------DAKISELEEELK 660
++ R+ + +L E VKS +AKI++LEE+++
Sbjct: 1789 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVE 1831
Score = 50.8 bits (116), Expect = 5e-06
Identities = 37/217 (17%), Positives = 92/217 (42%), Gaps = 1/217 (0%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++++ +++ + D M+ E+ N++ +++++ + +EE + +
Sbjct: 1341 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1400
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADE 432
+E + EEK E L +++ + DL+ + ++K + Q A+E
Sbjct: 1401 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1460
Query: 433 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 612
N K + R + + E ++ T L AR L E + K +E+ R ++ E+E
Sbjct: 1461 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSS 1519
Query: 613 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ ELE+ + + ++ ++ E+ ++
Sbjct: 1520 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQ 1556
Score = 49.6 bits (113), Expect = 1e-05
Identities = 51/219 (23%), Positives = 97/219 (44%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++ A D ++K + + ++ + Q + NL E++ E EL + ++
Sbjct: 852 EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEEMR 910
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
L K +LE+ ++E + ++ ++ A +K+ Q DLE+ E A+QKL
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 970
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
+ +A+ K LE+ MD N+L + R L E+ + +++ LA E+
Sbjct: 971 LEKVTAEAK---IKKLEDEILV----MDDQNNKLSKERKLLEE---RISDLTTNLAEEEE 1020
Query: 589 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+ + ++ ISELE LK S + LE + K
Sbjct: 1021 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRK 1059
Score = 47.6 bits (108), Expect = 4e-05
Identities = 45/206 (21%), Positives = 88/206 (42%), Gaps = 1/206 (0%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
K D A T E + R +K E + + ++ A + L KN+L+Q DL
Sbjct: 1377 KKKLQDFASTVEA-LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1435
Query: 289 EKQLTATEAEVAALNRKVQQI-EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 465
+ + RK Q+ E+ S + + + EA++ + + + LE
Sbjct: 1436 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 1495
Query: 466 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
+ EE + TN++ +A + ED D+V + + +E E +++ ++ EL
Sbjct: 1496 LEAKEEL--ERTNKMLKAEM--EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 1551
Query: 646 EEELKVVGNSLKSLEVSEEKANQRVE 723
E+EL+ ++ LEV+ + + E
Sbjct: 1552 EDELQATEDAKLRLEVNMQALKGQFE 1577
Score = 45.6 bits (103), Expect = 2e-04
Identities = 47/223 (21%), Positives = 102/223 (45%), Gaps = 9/223 (4%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 222
++ A +A +K+ +A+ L + + A++ + E+ + E + ++ K + +
Sbjct: 1470 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 1529
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 390
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E++
Sbjct: 1530 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1589
Query: 391 AQQKL---LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 561
+++L L ++ E+ R + L A++ +L LK+ L A+ A +E
Sbjct: 1590 KRRQLQRQLHEYETELEDERKQRALAAAAKK------KLEGDLKDLELQADSAIKGREEA 1643
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
++L ++ +++ + ++ A E+ K KSLE
Sbjct: 1644 IKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1686
Score = 42.3 bits (95), Expect = 0.002
Identities = 50/235 (21%), Positives = 102/235 (43%), Gaps = 11/235 (4%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADT----CEQQARDANLRAEKVNEEVRELQK-- 210
Q + T +A KK++ L D+ +K E++ D + E+ + L K
Sbjct: 970 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLK 1029
Query: 211 -KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAE----VAALNRKVQQIEEDLEKSE 375
K + +L + K E++ ++LE+ +++L ++ +A L ++ +++ L K E
Sbjct: 1030 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1089
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
E A +L + + A +NN + K+ E E + L L R A+ +
Sbjct: 1090 EELQAALARLDD--EIAQKNNALKKIREL-----EGHISDLQEDLDSERAARNKAEKQKR 1142
Query: 556 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
++ +L ++ ELE D + ++ E+E+ V+ +L S E Q +
Sbjct: 1143 DLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEM 1197
Score = 40.7 bits (91), Expect = 0.005
Identities = 41/180 (22%), Positives = 79/180 (43%), Gaps = 7/180 (3%)
Frame = +1
Query: 190 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 369
+V ++++ E++L K + ++A +L+E E++ + E L ++Q E +
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
Query: 370 SEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQ---DEERMDQ----LTNQLKEARLL 528
+EE K E ++ E + E+R QQ + ++M Q L QL+E
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 965
Query: 529 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
+ + K+ +EDE+ V +D+ + LEE + + +L EEKA
Sbjct: 966 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEER---ISDLTTNLAEEEEKA 1022
Score = 35.1 bits (77), Expect = 0.26
Identities = 27/100 (27%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++K A ++K+K + +K D+ EQ +AEK N V++L+++L + E
Sbjct: 1835 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE----QAEKGNARVKQLKRQLEEAE 1890
Query: 229 ED-LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 345
E+ +N N+ + ++L+E + A EV AL K++
Sbjct: 1891 EESQRINANR-RKLQRELDEATESNEAMGREVNALKSKLR 1929
>BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 55.6 bits (128), Expect = 2e-07
Identities = 55/249 (22%), Positives = 118/249 (47%), Gaps = 16/249 (6%)
Frame = +1
Query: 25 VFNSTGP*QQKAATMDAIKKKMQ-----AMKLEKDNAMDKADTCEQQARDANLRAEKVNE 189
+F + ++KA +++A ++Q A + K ++K + E+ A + R + +
Sbjct: 1671 IFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR-NALQD 1729
Query: 190 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 369
E R L+ ++AQ+EE+L + +E + + + +Q E+A Q+ E ++
Sbjct: 1730 EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ 1789
Query: 370 SEERSGTAQQKLLEAQQSADENNRMC-KVLENRAQQDEERMDQLTNQLKEARLLAEDADG 546
E ++ + KL E + + + LE + Q EE+++Q + + A + D
Sbjct: 1790 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1849
Query: 547 KSDEVSRKLAFVEDELEVAE---DRVKSGDAKISEL-------EEELKVVGNSLKSLEVS 696
K E+ L VEDE ++AE ++ + G+A++ +L EEE + + + + L+
Sbjct: 1850 KLKEI---LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1906
Query: 697 EEKANQRVE 723
++A + E
Sbjct: 1907 LDEATESNE 1915
Score = 54.0 bits (124), Expect = 5e-07
Identities = 38/200 (19%), Positives = 97/200 (48%), Gaps = 5/200 (2%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 1734 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNESA---RQQ 1789
Query: 256 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 1790 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1849
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 1850 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 1909
Query: 601 AEDRVKSGDAKISELEEELK 660
A + ++ +++ L+ +L+
Sbjct: 1910 ATESNEAMGREVNALKSKLR 1929
Score = 52.0 bits (119), Expect = 2e-06
Identities = 41/223 (18%), Positives = 103/223 (46%), Gaps = 19/223 (8%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 216
+++ A A KKK++ ++L+ D+A+ + +Q R + + E+ + +
Sbjct: 1609 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1668
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS-------E 375
++ N+ K + DL + ++ L A E + + +++ E+L S +
Sbjct: 1669 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ 1728
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
+ + ++ + ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 1729 DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ 1788
Query: 556 EVSRKLAFVEDELEVAEDRVKSG--------DAKISELEEELK 660
++ R+ + +L E VKS +AKI++LEE+++
Sbjct: 1789 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVE 1831
Score = 50.8 bits (116), Expect = 5e-06
Identities = 37/217 (17%), Positives = 92/217 (42%), Gaps = 1/217 (0%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++++ +++ + D M+ E+ N++ +++++ + +EE + +
Sbjct: 1341 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1400
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADE 432
+E + EEK E L +++ + DL+ + ++K + Q A+E
Sbjct: 1401 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1460
Query: 433 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 612
N K + R + + E ++ T L AR L E + K +E+ R ++ E+E
Sbjct: 1461 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSS 1519
Query: 613 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ ELE+ + + ++ ++ E+ ++
Sbjct: 1520 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQ 1556
Score = 49.6 bits (113), Expect = 1e-05
Identities = 51/219 (23%), Positives = 97/219 (44%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++ A D ++K + + ++ + Q + NL E++ E EL + ++
Sbjct: 852 EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEEMR 910
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
L K +LE+ ++E + ++ ++ A +K+ Q DLE+ E A+QKL
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 970
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
+ +A+ K LE+ MD N+L + R L E+ + +++ LA E+
Sbjct: 971 LEKVTAEAK---IKKLEDEILV----MDDQNNKLSKERKLLEE---RISDLTTNLAEEEE 1020
Query: 589 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+ + ++ ISELE LK S + LE + K
Sbjct: 1021 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRK 1059
Score = 47.6 bits (108), Expect = 4e-05
Identities = 45/206 (21%), Positives = 88/206 (42%), Gaps = 1/206 (0%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
K D A T E + R +K E + + ++ A + L KN+L+Q DL
Sbjct: 1377 KKKLQDFASTVEA-LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1435
Query: 289 EKQLTATEAEVAALNRKVQQI-EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 465
+ + RK Q+ E+ S + + + EA++ + + + LE
Sbjct: 1436 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 1495
Query: 466 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
+ EE + TN++ +A + ED D+V + + +E E +++ ++ EL
Sbjct: 1496 LEAKEEL--ERTNKMLKAEM--EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 1551
Query: 646 EEELKVVGNSLKSLEVSEEKANQRVE 723
E+EL+ ++ LEV+ + + E
Sbjct: 1552 EDELQATEDAKLRLEVNMQALKGQFE 1577
Score = 45.6 bits (103), Expect = 2e-04
Identities = 47/223 (21%), Positives = 102/223 (45%), Gaps = 9/223 (4%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 222
++ A +A +K+ +A+ L + + A++ + E+ + E + ++ K + +
Sbjct: 1470 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 1529
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 390
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E++
Sbjct: 1530 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1589
Query: 391 AQQKL---LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 561
+++L L ++ E+ R + L A++ +L LK+ L A+ A +E
Sbjct: 1590 KRRQLQRQLHEYETELEDERKQRALAAAAKK------KLEGDLKDLELQADSAIKGREEA 1643
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
++L ++ +++ + ++ A E+ K KSLE
Sbjct: 1644 IKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1686
Score = 42.3 bits (95), Expect = 0.002
Identities = 50/235 (21%), Positives = 102/235 (43%), Gaps = 11/235 (4%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADT----CEQQARDANLRAEKVNEEVRELQK-- 210
Q + T +A KK++ L D+ +K E++ D + E+ + L K
Sbjct: 970 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLK 1029
Query: 211 -KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAE----VAALNRKVQQIEEDLEKSE 375
K + +L + K E++ ++LE+ +++L ++ +A L ++ +++ L K E
Sbjct: 1030 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1089
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
E A +L + + A +NN + K+ E E + L L R A+ +
Sbjct: 1090 EELQAALARLDD--EIAQKNNALKKIREL-----EGHISDLQEDLDSERAARNKAEKQKR 1142
Query: 556 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
++ +L ++ ELE D + ++ E+E+ V+ +L S E Q +
Sbjct: 1143 DLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEM 1197
Score = 40.7 bits (91), Expect = 0.005
Identities = 41/180 (22%), Positives = 79/180 (43%), Gaps = 7/180 (3%)
Frame = +1
Query: 190 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 369
+V ++++ E++L K + ++A +L+E E++ + E L ++Q E +
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
Query: 370 SEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQ---DEERMDQ----LTNQLKEARLL 528
+EE K E ++ E + E+R QQ + ++M Q L QL+E
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 965
Query: 529 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
+ + K+ +EDE+ V +D+ + LEE + + +L EEKA
Sbjct: 966 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEER---ISDLTTNLAEEEEKA 1022
Score = 35.1 bits (77), Expect = 0.26
Identities = 27/100 (27%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++K A ++K+K + +K D+ EQ +AEK N V++L+++L + E
Sbjct: 1835 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE----QAEKGNARVKQLKRQLEEAE 1890
Query: 229 ED-LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 345
E+ +N N+ + ++L+E + A EV AL K++
Sbjct: 1891 EESQRINANR-RKLQRELDEATESNEAMGREVNALKSKLR 1929
>BC080545-1|AAH80545.1| 498|Homo sapiens MYH11 protein protein.
Length = 498
Score = 55.6 bits (128), Expect = 2e-07
Identities = 55/249 (22%), Positives = 118/249 (47%), Gaps = 16/249 (6%)
Frame = +1
Query: 25 VFNSTGP*QQKAATMDAIKKKMQ-----AMKLEKDNAMDKADTCEQQARDANLRAEKVNE 189
+F + ++KA +++A ++Q A + K ++K + E+ A + R + +
Sbjct: 197 IFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR-NALQD 255
Query: 190 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 369
E R L+ ++AQ+EE+L + +E + + + +Q E+A Q+ E ++
Sbjct: 256 EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ 315
Query: 370 SEERSGTAQQKLLEAQQSADENNRMC-KVLENRAQQDEERMDQLTNQLKEARLLAEDADG 546
E ++ + KL E + + + LE + Q EE+++Q + + A + D
Sbjct: 316 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 375
Query: 547 KSDEVSRKLAFVEDELEVAE---DRVKSGDAKISEL-------EEELKVVGNSLKSLEVS 696
K E+ L VEDE ++AE ++ + G+A++ +L EEE + + + + L+
Sbjct: 376 KLKEI---LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 432
Query: 697 EEKANQRVE 723
++A + E
Sbjct: 433 LDEATESNE 441
Score = 54.0 bits (124), Expect = 5e-07
Identities = 38/200 (19%), Positives = 97/200 (48%), Gaps = 5/200 (2%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 260 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNESA---RQQ 315
Query: 256 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 316 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 375
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 376 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 435
Query: 601 AEDRVKSGDAKISELEEELK 660
A + ++ +++ L+ +L+
Sbjct: 436 ATESNEAMGREVNALKSKLR 455
Score = 52.0 bits (119), Expect = 2e-06
Identities = 41/223 (18%), Positives = 103/223 (46%), Gaps = 19/223 (8%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 216
+++ A A KKK++ ++L+ D+A+ + +Q R + + E+ + +
Sbjct: 135 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 194
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS-------E 375
++ N+ K + DL + ++ L A E + + +++ E+L S +
Sbjct: 195 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ 254
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
+ + ++ + ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 255 DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ 314
Query: 556 EVSRKLAFVEDELEVAEDRVKSG--------DAKISELEEELK 660
++ R+ + +L E VKS +AKI++LEE+++
Sbjct: 315 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVE 357
Score = 44.4 bits (100), Expect = 4e-04
Identities = 46/216 (21%), Positives = 99/216 (45%), Gaps = 9/216 (4%)
Frame = +1
Query: 70 DAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
+A +K+ +A+ L + + A++ + E+ + E + ++ K + ++E+
Sbjct: 3 EAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRA 62
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGTAQQKL-- 405
+ ++E+ LEE E +L ATE L +Q Q E DL+ +E++ +++L
Sbjct: 63 LETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQR 122
Query: 406 -LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 582
L ++ E+ R + L A++ +L LK+ L A+ A +E ++L +
Sbjct: 123 QLHEYETELEDERKQRALAAAAKK------KLEGDLKDLELQADSAIKGREEAIKQLRKL 176
Query: 583 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
+ +++ + ++ A E+ K KSLE
Sbjct: 177 QAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 212
Score = 38.7 bits (86), Expect = 0.021
Identities = 33/129 (25%), Positives = 65/129 (50%), Gaps = 1/129 (0%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++K A ++K+K + +K D+ EQ +AEK N V++L+++L + E
Sbjct: 361 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE----QAEKGNARVKQLKRQLEEAE 416
Query: 229 ED-LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
E+ +N N+ + ++L+E + A EV AL K+++ E RSG +++
Sbjct: 417 EESQRINANR-RKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSG--GRRV 473
Query: 406 LEAQQSADE 432
+E ++E
Sbjct: 474 IENADGSEE 482
Score = 35.5 bits (78), Expect = 0.19
Identities = 24/105 (22%), Positives = 51/105 (48%)
Frame = +1
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
EA++ + + + LE + EE + TN++ +A + ED D+V + + +E
Sbjct: 3 EAREKETKALSLARALEEALEAKEEL--ERTNKMLKAEM--EDLVSSKDDVGKNVHELEK 58
Query: 589 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
E +++ ++ ELE+EL+ ++ LEV+ + + E
Sbjct: 59 SKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFE 103
>BC039612-1|AAH39612.1| 2002|Homo sapiens MYO18A protein protein.
Length = 2002
Score = 55.6 bits (128), Expect = 2e-07
Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 7/179 (3%)
Frame = +1
Query: 208 KKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI-------EEDLE 366
K A + ++ KN+LE++ K A E E+ L+ ++ I EE L
Sbjct: 1639 KNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLS 1698
Query: 367 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 546
+ + Q +L E Q+ +E + K +A +D +++ L QL+EA ++
Sbjct: 1699 RLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQE 1758
Query: 547 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
K + ++ F+E + V + V +AKI ELE L+ +K LE + + +E
Sbjct: 1759 KLQALQSQVEFLEQSM-VDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENME 1816
Score = 53.6 bits (123), Expect = 7e-07
Identities = 52/242 (21%), Positives = 122/242 (50%), Gaps = 18/242 (7%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++ T A K +AM++E ++ + D + + ++ E E+Q +L + +
Sbjct: 1656 EESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQ 1715
Query: 229 EDL--ILNKNK--LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE------- 375
ED+ ++ K+K + QA++DL Q+ +A++ N++ Q+++E L+ +
Sbjct: 1716 EDMNELMKKHKAAVAQASRDLA----QINDLQAQLEEANKEKQELQEKLQALQSQVEFLE 1771
Query: 376 ----ERSGTAQQ--KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 537
++S ++Q K+ E + + K LE+ A + +E M++LT + ++ R+ AE+
Sbjct: 1772 QSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEE-RDQRIAAEN 1830
Query: 538 ADGKSDE-VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
+ + ++ + R+L ++E+ + K ELE +L+ + + +SL+ + A +
Sbjct: 1831 REKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFK 1890
Query: 715 RV 720
R+
Sbjct: 1891 RI 1892
Score = 43.6 bits (98), Expect = 7e-04
Identities = 41/187 (21%), Positives = 83/187 (44%), Gaps = 5/187 (2%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
QQ + L E+ N+ R+L+++L ++ D ++ L+Q K + +L T+ +
Sbjct: 1390 QQEFEDKLEVEQQNK--RQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLE 1447
Query: 325 ALNRKVQQIEE-----DLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 489
+ ++E+ D E S+ ++KL + +++ + + + Q +E+ M
Sbjct: 1448 GQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDM 1507
Query: 490 DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVG 669
D K L AE D S E E L + +++ +AK+ + EEEL
Sbjct: 1508 DIAGFTQKVVSLEAELQDISSQESKD-----EASLAKVKKQLRDLEAKVKDQEEELDEQA 1562
Query: 670 NSLKSLE 690
+++ LE
Sbjct: 1563 GTIQMLE 1569
Score = 33.1 bits (72), Expect = 1.0
Identities = 48/205 (23%), Positives = 97/205 (47%), Gaps = 8/205 (3%)
Frame = +1
Query: 70 DAIKKKMQAMKL--EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 243
+A ++K+Q KL EKD + +A + +QQ + ++ ++V L+ +L +
Sbjct: 1473 EAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISS---- 1528
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ----KLLE 411
Q +KD E L + ++ L KV+ EE+L +E++GT Q K +E
Sbjct: 1529 ------QESKD----EASLAKVKKQLRDLEAKVKDQEEEL---DEQAGTIQMLEQLKQME 1575
Query: 412 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 591
Q + ++ KVL + ++ E ++ L++Q+ +E K ++ R A + D
Sbjct: 1576 VQLEEEYEDKQ-KVLREK-RELEGKLATLSDQVNRRDFESEKRLRK--DLKRTKALLADA 1631
Query: 592 LEVAEDRVKSGDAK--ISELEEELK 660
+ + S +K I++L+ +L+
Sbjct: 1632 QLMLDHLKNSAPSKREIAQLKNQLE 1656
>BC020921-1|AAH20921.1| 560|Homo sapiens ITSN2 protein protein.
Length = 560
Score = 55.6 bits (128), Expect = 2e-07
Identities = 51/207 (24%), Positives = 98/207 (47%), Gaps = 8/207 (3%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 261
+KMQ + +K + D + N+ EK + + E Q++ + E K + E
Sbjct: 347 QKMQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQR--EAERKAQKEKEEWE 404
Query: 262 QANKDLEEKE-KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 438
+ ++L+E+E K+ E + +Q EE+ K ER A+Q+L ++ E
Sbjct: 405 RKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERI 464
Query: 439 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-------EDELE 597
R ++L N+ +++E + +L ++ K L E +GK ++S +L V + ELE
Sbjct: 465 RRQELL-NQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELE 523
Query: 598 VAEDRVKSGDAKISELEEELKVVGNSL 678
V + + +I +L++EL+ N L
Sbjct: 524 VLDKQCDLEIMEIKQLQQELQEYQNKL 550
>AY703984-1|AAV80770.1| 1581|Homo sapiens SP-A receptor subunit
SP-R210 alphaS protein.
Length = 1581
Score = 55.6 bits (128), Expect = 2e-07
Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 7/179 (3%)
Frame = +1
Query: 208 KKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI-------EEDLE 366
K A + ++ KN+LE++ K A E E+ L+ ++ I EE L
Sbjct: 1218 KNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLS 1277
Query: 367 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 546
+ + Q +L E Q+ +E + K +A +D +++ L QL+EA ++
Sbjct: 1278 RLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQE 1337
Query: 547 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
K + ++ F+E + V + V +AKI ELE L+ +K LE + + +E
Sbjct: 1338 KLQALQSQVEFLEQSM-VDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENME 1395
Score = 53.6 bits (123), Expect = 7e-07
Identities = 52/242 (21%), Positives = 122/242 (50%), Gaps = 18/242 (7%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++ T A K +AM++E ++ + D + + ++ E E+Q +L + +
Sbjct: 1235 EESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQ 1294
Query: 229 EDL--ILNKNK--LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE------- 375
ED+ ++ K+K + QA++DL Q+ +A++ N++ Q+++E L+ +
Sbjct: 1295 EDMNELMKKHKAAVAQASRDLA----QINDLQAQLEEANKEKQELQEKLQALQSQVEFLE 1350
Query: 376 ----ERSGTAQQ--KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 537
++S ++Q K+ E + + K LE+ A + +E M++LT + ++ R+ AE+
Sbjct: 1351 QSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEE-RDQRIAAEN 1409
Query: 538 ADGKSDE-VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
+ + ++ + R+L ++E+ + K ELE +L+ + + +SL+ + A +
Sbjct: 1410 REKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFK 1469
Query: 715 RV 720
R+
Sbjct: 1470 RI 1471
Score = 45.2 bits (102), Expect = 2e-04
Identities = 42/198 (21%), Positives = 88/198 (44%), Gaps = 5/198 (2%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
QQ + L E+ N+ R+L+++L ++ D ++ L+Q K + +L T+ +
Sbjct: 932 QQEFEDKLEVEQQNK--RQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLE 989
Query: 325 ALNRKVQQIEE-----DLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 489
+ ++E+ D E S+ ++KL + +++ + + + Q +E+ M
Sbjct: 990 GQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDM 1049
Query: 490 DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVG 669
D K L AE D S E E L + +++ +AK+ + EEEL
Sbjct: 1050 DIAGFTQKVVSLEAELQDISSQESKD-----EASLAKVKKQLRDLEAKVKDQEEELDEQA 1104
Query: 670 NSLKSLEVSEEKANQRVE 723
+++ LE ++ + +E
Sbjct: 1105 GTIQMLEQAKLRLEMEME 1122
Score = 41.1 bits (92), Expect = 0.004
Identities = 52/229 (22%), Positives = 101/229 (44%), Gaps = 11/229 (4%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKL---EKDNAMDKADTCEQQARDANLRAEKVNEEVR-----ELQKKL 216
A++ +KK+++ ++ +++ +D+ Q A LR E E +R E++ +
Sbjct: 1077 ASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRD 1136
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 396
+VEE + KL+Q LEE+ + E L K+ + + + + + S
Sbjct: 1137 EEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRL 1196
Query: 397 QKLLEAQQS-ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 573
+K L+ ++ + M L+N A E + QL NQL+E+ A +RK
Sbjct: 1197 RKDLKRTKALLADAQLMLDHLKNSAPSKRE-IAQLKNQLEESEFTCAAA-----VKARKA 1250
Query: 574 AFVE-DELEVAEDRVKSGDAKISELEEELKVVGNSLKS-LEVSEEKANQ 714
VE ++L + D + + E L+ N +++ LE +E N+
Sbjct: 1251 MEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNE 1299
>AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin heavy
chain isoform SM2 protein.
Length = 1945
Score = 55.6 bits (128), Expect = 2e-07
Identities = 55/249 (22%), Positives = 118/249 (47%), Gaps = 16/249 (6%)
Frame = +1
Query: 25 VFNSTGP*QQKAATMDAIKKKMQ-----AMKLEKDNAMDKADTCEQQARDANLRAEKVNE 189
+F + ++KA +++A ++Q A + K ++K + E+ A + R + +
Sbjct: 1678 IFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR-NALQD 1736
Query: 190 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 369
E R L+ ++AQ+EE+L + +E + + + +Q E+A Q+ E ++
Sbjct: 1737 EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ 1796
Query: 370 SEERSGTAQQKLLEAQQSADENNRMC-KVLENRAQQDEERMDQLTNQLKEARLLAEDADG 546
E ++ + KL E + + + LE + Q EE+++Q + + A + D
Sbjct: 1797 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1856
Query: 547 KSDEVSRKLAFVEDELEVAE---DRVKSGDAKISEL-------EEELKVVGNSLKSLEVS 696
K E+ L VEDE ++AE ++ + G+A++ +L EEE + + + + L+
Sbjct: 1857 KLKEI---LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1913
Query: 697 EEKANQRVE 723
++A + E
Sbjct: 1914 LDEATESNE 1922
Score = 54.0 bits (124), Expect = 5e-07
Identities = 38/200 (19%), Positives = 97/200 (48%), Gaps = 5/200 (2%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 1741 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNESA---RQQ 1796
Query: 256 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 1797 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1856
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 1857 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 1916
Query: 601 AEDRVKSGDAKISELEEELK 660
A + ++ +++ L+ +L+
Sbjct: 1917 ATESNEAMGREVNALKSKLR 1936
Score = 52.0 bits (119), Expect = 2e-06
Identities = 41/223 (18%), Positives = 103/223 (46%), Gaps = 19/223 (8%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 216
+++ A A KKK++ ++L+ D+A+ + +Q R + + E+ + +
Sbjct: 1616 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1675
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS-------E 375
++ N+ K + DL + ++ L A E + + +++ E+L S +
Sbjct: 1676 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ 1735
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
+ + ++ + ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 1736 DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ 1795
Query: 556 EVSRKLAFVEDELEVAEDRVKSG--------DAKISELEEELK 660
++ R+ + +L E VKS +AKI++LEE+++
Sbjct: 1796 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVE 1838
Score = 50.8 bits (116), Expect = 5e-06
Identities = 37/217 (17%), Positives = 92/217 (42%), Gaps = 1/217 (0%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++++ +++ + D M+ E+ N++ +++++ + +EE + +
Sbjct: 1348 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1407
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADE 432
+E + EEK E L +++ + DL+ + ++K + Q A+E
Sbjct: 1408 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1467
Query: 433 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 612
N K + R + + E ++ T L AR L E + K +E+ R ++ E+E
Sbjct: 1468 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSS 1526
Query: 613 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ ELE+ + + ++ ++ E+ ++
Sbjct: 1527 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQ 1563
Score = 49.6 bits (113), Expect = 1e-05
Identities = 51/219 (23%), Positives = 97/219 (44%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++ A D ++K + + ++ + Q + NL E++ E EL + ++
Sbjct: 859 EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEEMR 917
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
L K +LE+ ++E + ++ ++ A +K+ Q DLE+ E A+QKL
Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 977
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
+ +A+ K LE+ MD N+L + R L E+ + +++ LA E+
Sbjct: 978 LEKVTAEAK---IKKLEDEILV----MDDQNNKLSKERKLLEE---RISDLTTNLAEEEE 1027
Query: 589 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+ + ++ ISELE LK S + LE + K
Sbjct: 1028 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRK 1066
Score = 47.6 bits (108), Expect = 4e-05
Identities = 45/206 (21%), Positives = 88/206 (42%), Gaps = 1/206 (0%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
K D A T E + R +K E + + ++ A + L KN+L+Q DL
Sbjct: 1384 KKKLQDFASTVEA-LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1442
Query: 289 EKQLTATEAEVAALNRKVQQI-EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 465
+ + RK Q+ E+ S + + + EA++ + + + LE
Sbjct: 1443 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 1502
Query: 466 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
+ EE + TN++ +A + ED D+V + + +E E +++ ++ EL
Sbjct: 1503 LEAKEEL--ERTNKMLKAEM--EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 1558
Query: 646 EEELKVVGNSLKSLEVSEEKANQRVE 723
E+EL+ ++ LEV+ + + E
Sbjct: 1559 EDELQATEDAKLRLEVNMQALKGQFE 1584
Score = 45.6 bits (103), Expect = 2e-04
Identities = 47/223 (21%), Positives = 102/223 (45%), Gaps = 9/223 (4%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 222
++ A +A +K+ +A+ L + + A++ + E+ + E + ++ K + +
Sbjct: 1477 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 1536
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 390
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E++
Sbjct: 1537 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1596
Query: 391 AQQKL---LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 561
+++L L ++ E+ R + L A++ +L LK+ L A+ A +E
Sbjct: 1597 KRRQLQRQLHEYETELEDERKQRALAAAAKK------KLEGDLKDLELQADSAIKGREEA 1650
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
++L ++ +++ + ++ A E+ K KSLE
Sbjct: 1651 IKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1693
Score = 42.3 bits (95), Expect = 0.002
Identities = 50/235 (21%), Positives = 102/235 (43%), Gaps = 11/235 (4%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADT----CEQQARDANLRAEKVNEEVRELQK-- 210
Q + T +A KK++ L D+ +K E++ D + E+ + L K
Sbjct: 977 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLK 1036
Query: 211 -KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAE----VAALNRKVQQIEEDLEKSE 375
K + +L + K E++ ++LE+ +++L ++ +A L ++ +++ L K E
Sbjct: 1037 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1096
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
E A +L + + A +NN + K+ E E + L L R A+ +
Sbjct: 1097 EELQAALARLDD--EIAQKNNALKKIREL-----EGHISDLQEDLDSERAARNKAEKQKR 1149
Query: 556 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
++ +L ++ ELE D + ++ E+E+ V+ +L S E Q +
Sbjct: 1150 DLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEM 1204
Score = 40.7 bits (91), Expect = 0.005
Identities = 41/180 (22%), Positives = 79/180 (43%), Gaps = 7/180 (3%)
Frame = +1
Query: 190 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 369
+V ++++ E++L K + ++A +L+E E++ + E L ++Q E +
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912
Query: 370 SEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQ---DEERMDQ----LTNQLKEARLL 528
+EE K E ++ E + E+R QQ + ++M Q L QL+E
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 972
Query: 529 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
+ + K+ +EDE+ V +D+ + LEE + + +L EEKA
Sbjct: 973 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEER---ISDLTTNLAEEEEKA 1029
Score = 35.1 bits (77), Expect = 0.26
Identities = 27/100 (27%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++K A ++K+K + +K D+ EQ +AEK N V++L+++L + E
Sbjct: 1842 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE----QAEKGNARVKQLKRQLEEAE 1897
Query: 229 ED-LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 345
E+ +N N+ + ++L+E + A EV AL K++
Sbjct: 1898 EESQRINANR-RKLQRELDEATESNEAMGREVNALKSKLR 1936
>AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin heavy
chain isoform SM1 protein.
Length = 1979
Score = 55.6 bits (128), Expect = 2e-07
Identities = 55/249 (22%), Positives = 118/249 (47%), Gaps = 16/249 (6%)
Frame = +1
Query: 25 VFNSTGP*QQKAATMDAIKKKMQ-----AMKLEKDNAMDKADTCEQQARDANLRAEKVNE 189
+F + ++KA +++A ++Q A + K ++K + E+ A + R + +
Sbjct: 1678 IFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR-NALQD 1736
Query: 190 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 369
E R L+ ++AQ+EE+L + +E + + + +Q E+A Q+ E ++
Sbjct: 1737 EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ 1796
Query: 370 SEERSGTAQQKLLEAQQSADENNRMC-KVLENRAQQDEERMDQLTNQLKEARLLAEDADG 546
E ++ + KL E + + + LE + Q EE+++Q + + A + D
Sbjct: 1797 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1856
Query: 547 KSDEVSRKLAFVEDELEVAE---DRVKSGDAKISEL-------EEELKVVGNSLKSLEVS 696
K E+ L VEDE ++AE ++ + G+A++ +L EEE + + + + L+
Sbjct: 1857 KLKEI---LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1913
Query: 697 EEKANQRVE 723
++A + E
Sbjct: 1914 LDEATESNE 1922
Score = 54.0 bits (124), Expect = 5e-07
Identities = 38/200 (19%), Positives = 97/200 (48%), Gaps = 5/200 (2%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 1741 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNESA---RQQ 1796
Query: 256 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 1797 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1856
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 1857 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 1916
Query: 601 AEDRVKSGDAKISELEEELK 660
A + ++ +++ L+ +L+
Sbjct: 1917 ATESNEAMGREVNALKSKLR 1936
Score = 52.0 bits (119), Expect = 2e-06
Identities = 41/223 (18%), Positives = 103/223 (46%), Gaps = 19/223 (8%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 216
+++ A A KKK++ ++L+ D+A+ + +Q R + + E+ + +
Sbjct: 1616 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1675
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS-------E 375
++ N+ K + DL + ++ L A E + + +++ E+L S +
Sbjct: 1676 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ 1735
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
+ + ++ + ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 1736 DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ 1795
Query: 556 EVSRKLAFVEDELEVAEDRVKSG--------DAKISELEEELK 660
++ R+ + +L E VKS +AKI++LEE+++
Sbjct: 1796 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVE 1838
Score = 50.8 bits (116), Expect = 5e-06
Identities = 37/217 (17%), Positives = 92/217 (42%), Gaps = 1/217 (0%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++++ +++ + D M+ E+ N++ +++++ + +EE + +
Sbjct: 1348 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1407
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADE 432
+E + EEK E L +++ + DL+ + ++K + Q A+E
Sbjct: 1408 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1467
Query: 433 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 612
N K + R + + E ++ T L AR L E + K +E+ R ++ E+E
Sbjct: 1468 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSS 1526
Query: 613 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ ELE+ + + ++ ++ E+ ++
Sbjct: 1527 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQ 1563
Score = 49.6 bits (113), Expect = 1e-05
Identities = 51/219 (23%), Positives = 97/219 (44%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++ A D ++K + + ++ + Q + NL E++ E EL + ++
Sbjct: 859 EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEEMR 917
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
L K +LE+ ++E + ++ ++ A +K+ Q DLE+ E A+QKL
Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 977
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
+ +A+ K LE+ MD N+L + R L E+ + +++ LA E+
Sbjct: 978 LEKVTAEAK---IKKLEDEILV----MDDQNNKLSKERKLLEE---RISDLTTNLAEEEE 1027
Query: 589 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+ + ++ ISELE LK S + LE + K
Sbjct: 1028 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRK 1066
Score = 47.6 bits (108), Expect = 4e-05
Identities = 45/206 (21%), Positives = 88/206 (42%), Gaps = 1/206 (0%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
K D A T E + R +K E + + ++ A + L KN+L+Q DL
Sbjct: 1384 KKKLQDFASTVEA-LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1442
Query: 289 EKQLTATEAEVAALNRKVQQI-EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 465
+ + RK Q+ E+ S + + + EA++ + + + LE
Sbjct: 1443 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 1502
Query: 466 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
+ EE + TN++ +A + ED D+V + + +E E +++ ++ EL
Sbjct: 1503 LEAKEEL--ERTNKMLKAEM--EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 1558
Query: 646 EEELKVVGNSLKSLEVSEEKANQRVE 723
E+EL+ ++ LEV+ + + E
Sbjct: 1559 EDELQATEDAKLRLEVNMQALKGQFE 1584
Score = 45.6 bits (103), Expect = 2e-04
Identities = 47/223 (21%), Positives = 102/223 (45%), Gaps = 9/223 (4%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 222
++ A +A +K+ +A+ L + + A++ + E+ + E + ++ K + +
Sbjct: 1477 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 1536
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 390
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E++
Sbjct: 1537 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1596
Query: 391 AQQKL---LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 561
+++L L ++ E+ R + L A++ +L LK+ L A+ A +E
Sbjct: 1597 KRRQLQRQLHEYETELEDERKQRALAAAAKK------KLEGDLKDLELQADSAIKGREEA 1650
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
++L ++ +++ + ++ A E+ K KSLE
Sbjct: 1651 IKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1693
Score = 42.3 bits (95), Expect = 0.002
Identities = 50/235 (21%), Positives = 102/235 (43%), Gaps = 11/235 (4%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADT----CEQQARDANLRAEKVNEEVRELQK-- 210
Q + T +A KK++ L D+ +K E++ D + E+ + L K
Sbjct: 977 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLK 1036
Query: 211 -KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAE----VAALNRKVQQIEEDLEKSE 375
K + +L + K E++ ++LE+ +++L ++ +A L ++ +++ L K E
Sbjct: 1037 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1096
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
E A +L + + A +NN + K+ E E + L L R A+ +
Sbjct: 1097 EELQAALARLDD--EIAQKNNALKKIREL-----EGHISDLQEDLDSERAARNKAEKQKR 1149
Query: 556 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
++ +L ++ ELE D + ++ E+E+ V+ +L S E Q +
Sbjct: 1150 DLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEM 1204
Score = 40.7 bits (91), Expect = 0.005
Identities = 41/180 (22%), Positives = 79/180 (43%), Gaps = 7/180 (3%)
Frame = +1
Query: 190 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 369
+V ++++ E++L K + ++A +L+E E++ + E L ++Q E +
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912
Query: 370 SEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQ---DEERMDQ----LTNQLKEARLL 528
+EE K E ++ E + E+R QQ + ++M Q L QL+E
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 972
Query: 529 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
+ + K+ +EDE+ V +D+ + LEE + + +L EEKA
Sbjct: 973 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEER---ISDLTTNLAEEEEKA 1029
Score = 38.7 bits (86), Expect = 0.021
Identities = 33/129 (25%), Positives = 65/129 (50%), Gaps = 1/129 (0%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++K A ++K+K + +K D+ EQ +AEK N V++L+++L + E
Sbjct: 1842 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE----QAEKGNARVKQLKRQLEEAE 1897
Query: 229 ED-LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
E+ +N N+ + ++L+E + A EV AL K+++ E RSG +++
Sbjct: 1898 EESQRINANR-RKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSG--GRRV 1954
Query: 406 LEAQQSADE 432
+E ++E
Sbjct: 1955 IENADGSEE 1963
>AL832636-1|CAD89951.1| 546|Homo sapiens hypothetical protein
protein.
Length = 546
Score = 55.6 bits (128), Expect = 2e-07
Identities = 47/213 (22%), Positives = 103/213 (48%), Gaps = 7/213 (3%)
Frame = +1
Query: 88 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 267
+Q + E++ + + D L+ E+ NE +L+++ ++ E L K +EQ
Sbjct: 260 VQRAREEEEKRKEVTSHFQVTLNDIQLQMEQHNERNSKLRQENMELAERL---KKLIEQY 316
Query: 268 NKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMC 447
E +K + + ++ K+QQ +E L+++EER + LL + A E+ RMC
Sbjct: 317 ELREEHIDKVFKHKDLQQQLVDAKLQQAQEMLKEAEERHQREKDFLL---KEAVESQRMC 373
Query: 448 KVL---ENRAQQD----EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
+++ E +Q E+ ++ N L ++ + + + +++++K+ +E E +
Sbjct: 374 ELMKQQETHLKQQLALYTEKFEEFQNTLSKSSEVFTTFEQEMEKMTKKIKKLEKETTMYR 433
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
R +S + + E+ EE V L+ L+V ++
Sbjct: 434 SRWESSNKALLEMAEEKTVRDKELEGLQVKIQR 466
Score = 38.3 bits (85), Expect = 0.028
Identities = 15/57 (26%), Positives = 37/57 (64%)
Frame = +1
Query: 187 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE 357
+E+ ++ KK+ ++E++ + +++ E +NK L E ++ T + E+ L K+Q++E+
Sbjct: 413 QEMEKMTKKIKKLEKETTMYRSRWESSNKALLEMAEEKTVRDKELEGLQVKIQRLEK 469
>AF110265-1|AAF21930.1| 864|Homo sapiens epidermal growth factor
receptor substrate EPS15R protein.
Length = 864
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/144 (21%), Positives = 68/144 (47%)
Frame = +1
Query: 292 KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 471
K+L E+A L R+ +E+D+ + EE ++ E Q D + LE + Q
Sbjct: 384 KELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQ 443
Query: 472 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE 651
++R+D++ Q + R + D K + ++ ++ ++ +++ E +KS + ++ +
Sbjct: 444 DAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKS 503
Query: 652 ELKVVGNSLKSLEVSEEKANQRVE 723
EL + LE S + ++E
Sbjct: 504 ELNRLQQEETQLEQSIQAGRVQLE 527
>AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin heavy
chain SM1 protein.
Length = 622
Score = 55.6 bits (128), Expect = 2e-07
Identities = 55/249 (22%), Positives = 118/249 (47%), Gaps = 16/249 (6%)
Frame = +1
Query: 25 VFNSTGP*QQKAATMDAIKKKMQ-----AMKLEKDNAMDKADTCEQQARDANLRAEKVNE 189
+F + ++KA +++A ++Q A + K ++K + E+ A + R + +
Sbjct: 321 IFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR-NALQD 379
Query: 190 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 369
E R L+ ++AQ+EE+L + +E + + + +Q E+A Q+ E ++
Sbjct: 380 EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ 439
Query: 370 SEERSGTAQQKLLEAQQSADENNRMC-KVLENRAQQDEERMDQLTNQLKEARLLAEDADG 546
E ++ + KL E + + + LE + Q EE+++Q + + A + D
Sbjct: 440 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 499
Query: 547 KSDEVSRKLAFVEDELEVAE---DRVKSGDAKISEL-------EEELKVVGNSLKSLEVS 696
K E+ L VEDE ++AE ++ + G+A++ +L EEE + + + + L+
Sbjct: 500 KLKEI---LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 556
Query: 697 EEKANQRVE 723
++A + E
Sbjct: 557 LDEATESNE 565
Score = 54.0 bits (124), Expect = 5e-07
Identities = 38/200 (19%), Positives = 97/200 (48%), Gaps = 5/200 (2%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 384 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNESA---RQQ 439
Query: 256 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 440 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 499
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 500 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 559
Query: 601 AEDRVKSGDAKISELEEELK 660
A + ++ +++ L+ +L+
Sbjct: 560 ATESNEAMGREVNALKSKLR 579
Score = 50.4 bits (115), Expect = 6e-06
Identities = 40/223 (17%), Positives = 102/223 (45%), Gaps = 19/223 (8%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 216
+++ A A KKK++ ++L+ D+A+ + + R + + E+ + +
Sbjct: 259 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKHVRKLQAQMKDFQRELEDARASR 318
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS-------E 375
++ N+ K + DL + ++ L A E + + +++ E+L S +
Sbjct: 319 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ 378
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
+ + ++ + ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 379 DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ 438
Query: 556 EVSRKLAFVEDELEVAEDRVKSG--------DAKISELEEELK 660
++ R+ + +L E VKS +AKI++LEE+++
Sbjct: 439 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVE 481
Score = 47.6 bits (108), Expect = 4e-05
Identities = 45/206 (21%), Positives = 88/206 (42%), Gaps = 1/206 (0%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
K D A T E + R +K E + + ++ A + L KN+L+Q DL
Sbjct: 27 KKKLQDFASTVEA-LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 85
Query: 289 EKQLTATEAEVAALNRKVQQI-EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 465
+ + RK Q+ E+ S + + + EA++ + + + LE
Sbjct: 86 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 145
Query: 466 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
+ EE + TN++ +A + ED D+V + + +E E +++ ++ EL
Sbjct: 146 LEAKEEL--ERTNKMLKAEM--EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 201
Query: 646 EEELKVVGNSLKSLEVSEEKANQRVE 723
E+EL+ ++ LEV+ + + E
Sbjct: 202 EDELQATEDAKLRLEVNMQALKGQFE 227
Score = 47.2 bits (107), Expect = 6e-05
Identities = 36/202 (17%), Positives = 83/202 (41%), Gaps = 1/202 (0%)
Frame = +1
Query: 121 MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQL 300
M+ E+ N++ +++++ + +EE + ++E + EEK
Sbjct: 6 MEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAY 65
Query: 301 TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADENNRMCKVLENRAQQD 477
E L +++ + DL+ + ++K + Q A+E N K + R + +
Sbjct: 66 DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE 125
Query: 478 EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 657
E ++ T L AR L E + K +E+ R ++ E+E + ELE+
Sbjct: 126 AEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 184
Query: 658 KVVGNSLKSLEVSEEKANQRVE 723
+ + ++ ++ E+ ++
Sbjct: 185 RALETQMEEMKTQLEELEDELQ 206
Score = 43.6 bits (98), Expect = 7e-04
Identities = 46/223 (20%), Positives = 101/223 (45%), Gaps = 9/223 (4%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 222
++ A +A +K+ +A+ L + + A++ + E+ + E + ++ K + +
Sbjct: 120 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 179
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 390
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E++
Sbjct: 180 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 239
Query: 391 AQQKL---LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 561
+++L L ++ E+ R + L A++ +L LK+ L A+ A +E
Sbjct: 240 KRRQLQRQLHEYETELEDERKQRALAAAAKK------KLEGDLKDLELQADSAIKGREEA 293
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
+ + ++ +++ + ++ A E+ K KSLE
Sbjct: 294 IKHVRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 336
Score = 38.7 bits (86), Expect = 0.021
Identities = 33/129 (25%), Positives = 65/129 (50%), Gaps = 1/129 (0%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++K A ++K+K + +K D+ EQ +AEK N V++L+++L + E
Sbjct: 485 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE----QAEKGNARVKQLKRQLEEAE 540
Query: 229 ED-LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
E+ +N N+ + ++L+E + A EV AL K+++ E RSG +++
Sbjct: 541 EESQRINANR-RKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSG--GRRV 597
Query: 406 LEAQQSADE 432
+E ++E
Sbjct: 598 IENADGSEE 606
>AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin heavy
chain SM2 protein.
Length = 588
Score = 55.6 bits (128), Expect = 2e-07
Identities = 55/249 (22%), Positives = 118/249 (47%), Gaps = 16/249 (6%)
Frame = +1
Query: 25 VFNSTGP*QQKAATMDAIKKKMQ-----AMKLEKDNAMDKADTCEQQARDANLRAEKVNE 189
+F + ++KA +++A ++Q A + K ++K + E+ A + R + +
Sbjct: 321 IFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR-NALQD 379
Query: 190 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 369
E R L+ ++AQ+EE+L + +E + + + +Q E+A Q+ E ++
Sbjct: 380 EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ 439
Query: 370 SEERSGTAQQKLLEAQQSADENNRMC-KVLENRAQQDEERMDQLTNQLKEARLLAEDADG 546
E ++ + KL E + + + LE + Q EE+++Q + + A + D
Sbjct: 440 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 499
Query: 547 KSDEVSRKLAFVEDELEVAE---DRVKSGDAKISEL-------EEELKVVGNSLKSLEVS 696
K E+ L VEDE ++AE ++ + G+A++ +L EEE + + + + L+
Sbjct: 500 KLKEI---LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 556
Query: 697 EEKANQRVE 723
++A + E
Sbjct: 557 LDEATESNE 565
Score = 54.0 bits (124), Expect = 5e-07
Identities = 38/200 (19%), Positives = 97/200 (48%), Gaps = 5/200 (2%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 384 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNESA---RQQ 439
Query: 256 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 440 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 499
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 500 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 559
Query: 601 AEDRVKSGDAKISELEEELK 660
A + ++ +++ L+ +L+
Sbjct: 560 ATESNEAMGREVNALKSKLR 579
Score = 50.4 bits (115), Expect = 6e-06
Identities = 40/223 (17%), Positives = 102/223 (45%), Gaps = 19/223 (8%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 216
+++ A A KKK++ ++L+ D+A+ + + R + + E+ + +
Sbjct: 259 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKHVRKLQAQMKDFQRELEDARASR 318
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS-------E 375
++ N+ K + DL + ++ L A E + + +++ E+L S +
Sbjct: 319 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ 378
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
+ + ++ + ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 379 DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ 438
Query: 556 EVSRKLAFVEDELEVAEDRVKSG--------DAKISELEEELK 660
++ R+ + +L E VKS +AKI++LEE+++
Sbjct: 439 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVE 481
Score = 47.6 bits (108), Expect = 4e-05
Identities = 45/206 (21%), Positives = 88/206 (42%), Gaps = 1/206 (0%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
K D A T E + R +K E + + ++ A + L KN+L+Q DL
Sbjct: 27 KKKLQDFASTVEA-LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 85
Query: 289 EKQLTATEAEVAALNRKVQQI-EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 465
+ + RK Q+ E+ S + + + EA++ + + + LE
Sbjct: 86 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 145
Query: 466 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
+ EE + TN++ +A + ED D+V + + +E E +++ ++ EL
Sbjct: 146 LEAKEEL--ERTNKMLKAEM--EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 201
Query: 646 EEELKVVGNSLKSLEVSEEKANQRVE 723
E+EL+ ++ LEV+ + + E
Sbjct: 202 EDELQATEDAKLRLEVNMQALKGQFE 227
Score = 47.2 bits (107), Expect = 6e-05
Identities = 36/202 (17%), Positives = 83/202 (41%), Gaps = 1/202 (0%)
Frame = +1
Query: 121 MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQL 300
M+ E+ N++ +++++ + +EE + ++E + EEK
Sbjct: 6 MEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAY 65
Query: 301 TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADENNRMCKVLENRAQQD 477
E L +++ + DL+ + ++K + Q A+E N K + R + +
Sbjct: 66 DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE 125
Query: 478 EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 657
E ++ T L AR L E + K +E+ R ++ E+E + ELE+
Sbjct: 126 AEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 184
Query: 658 KVVGNSLKSLEVSEEKANQRVE 723
+ + ++ ++ E+ ++
Sbjct: 185 RALETQMEEMKTQLEELEDELQ 206
Score = 43.6 bits (98), Expect = 7e-04
Identities = 46/223 (20%), Positives = 101/223 (45%), Gaps = 9/223 (4%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 222
++ A +A +K+ +A+ L + + A++ + E+ + E + ++ K + +
Sbjct: 120 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 179
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 390
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E++
Sbjct: 180 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 239
Query: 391 AQQKL---LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 561
+++L L ++ E+ R + L A++ +L LK+ L A+ A +E
Sbjct: 240 KRRQLQRQLHEYETELEDERKQRALAAAAKK------KLEGDLKDLELQADSAIKGREEA 293
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
+ + ++ +++ + ++ A E+ K KSLE
Sbjct: 294 IKHVRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 336
Score = 35.1 bits (77), Expect = 0.26
Identities = 27/100 (27%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++K A ++K+K + +K D+ EQ +AEK N V++L+++L + E
Sbjct: 485 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE----QAEKGNARVKQLKRQLEEAE 540
Query: 229 ED-LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 345
E+ +N N+ + ++L+E + A EV AL K++
Sbjct: 541 EESQRINANR-RKLQRELDEATESNEAMGREVNALKSKLR 579
>AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY11)
(5'partial) protein.
Length = 1857
Score = 55.6 bits (128), Expect = 2e-07
Identities = 55/249 (22%), Positives = 118/249 (47%), Gaps = 16/249 (6%)
Frame = +1
Query: 25 VFNSTGP*QQKAATMDAIKKKMQ-----AMKLEKDNAMDKADTCEQQARDANLRAEKVNE 189
+F + ++KA +++A ++Q A + K ++K + E+ A + R + +
Sbjct: 1556 IFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR-NALQD 1614
Query: 190 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 369
E R L+ ++AQ+EE+L + +E + + + +Q E+A Q+ E ++
Sbjct: 1615 EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ 1674
Query: 370 SEERSGTAQQKLLEAQQSADENNRMC-KVLENRAQQDEERMDQLTNQLKEARLLAEDADG 546
E ++ + KL E + + + LE + Q EE+++Q + + A + D
Sbjct: 1675 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1734
Query: 547 KSDEVSRKLAFVEDELEVAE---DRVKSGDAKISEL-------EEELKVVGNSLKSLEVS 696
K E+ L VEDE ++AE ++ + G+A++ +L EEE + + + + L+
Sbjct: 1735 KLKEI---LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1791
Query: 697 EEKANQRVE 723
++A + E
Sbjct: 1792 LDEATESNE 1800
Score = 54.0 bits (124), Expect = 5e-07
Identities = 38/200 (19%), Positives = 97/200 (48%), Gaps = 5/200 (2%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 1619 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNESA---RQQ 1674
Query: 256 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 1675 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1734
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 1735 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 1794
Query: 601 AEDRVKSGDAKISELEEELK 660
A + ++ +++ L+ +L+
Sbjct: 1795 ATESNEAMGREVNALKSKLR 1814
Score = 52.0 bits (119), Expect = 2e-06
Identities = 41/223 (18%), Positives = 103/223 (46%), Gaps = 19/223 (8%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 216
+++ A A KKK++ ++L+ D+A+ + +Q R + + E+ + +
Sbjct: 1494 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1553
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS-------E 375
++ N+ K + DL + ++ L A E + + +++ E+L S +
Sbjct: 1554 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ 1613
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
+ + ++ + ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 1614 DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ 1673
Query: 556 EVSRKLAFVEDELEVAEDRVKSG--------DAKISELEEELK 660
++ R+ + +L E VKS +AKI++LEE+++
Sbjct: 1674 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVE 1716
Score = 50.8 bits (116), Expect = 5e-06
Identities = 37/217 (17%), Positives = 92/217 (42%), Gaps = 1/217 (0%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++++ +++ + D M+ E+ N++ +++++ + +EE + +
Sbjct: 1226 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1285
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADE 432
+E + EEK E L +++ + DL+ + ++K + Q A+E
Sbjct: 1286 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1345
Query: 433 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 612
N K + R + + E ++ T L AR L E + K +E+ R ++ E+E
Sbjct: 1346 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSS 1404
Query: 613 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ ELE+ + + ++ ++ E+ ++
Sbjct: 1405 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQ 1441
Score = 49.6 bits (113), Expect = 1e-05
Identities = 51/219 (23%), Positives = 97/219 (44%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++ A D ++K + + ++ + Q + NL E++ E EL + ++
Sbjct: 737 EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEEMR 795
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
L K +LE+ ++E + ++ ++ A +K+ Q DLE+ E A+QKL
Sbjct: 796 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 855
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
+ +A+ K LE+ MD N+L + R L E+ + +++ LA E+
Sbjct: 856 LEKVTAEAK---IKKLEDEILV----MDDQNNKLSKERKLLEE---RISDLTTNLAEEEE 905
Query: 589 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+ + ++ ISELE LK S + LE + K
Sbjct: 906 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRK 944
Score = 47.6 bits (108), Expect = 4e-05
Identities = 45/206 (21%), Positives = 88/206 (42%), Gaps = 1/206 (0%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
K D A T E + R +K E + + ++ A + L KN+L+Q DL
Sbjct: 1262 KKKLQDFASTVEA-LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1320
Query: 289 EKQLTATEAEVAALNRKVQQI-EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 465
+ + RK Q+ E+ S + + + EA++ + + + LE
Sbjct: 1321 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 1380
Query: 466 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
+ EE + TN++ +A + ED D+V + + +E E +++ ++ EL
Sbjct: 1381 LEAKEEL--ERTNKMLKAEM--EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 1436
Query: 646 EEELKVVGNSLKSLEVSEEKANQRVE 723
E+EL+ ++ LEV+ + + E
Sbjct: 1437 EDELQATEDAKLRLEVNMQALKGQFE 1462
Score = 45.6 bits (103), Expect = 2e-04
Identities = 47/223 (21%), Positives = 102/223 (45%), Gaps = 9/223 (4%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 222
++ A +A +K+ +A+ L + + A++ + E+ + E + ++ K + +
Sbjct: 1355 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 1414
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 390
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E++
Sbjct: 1415 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1474
Query: 391 AQQKL---LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 561
+++L L ++ E+ R + L A++ +L LK+ L A+ A +E
Sbjct: 1475 KRRQLQRQLHEYETELEDERKQRALAAAAKK------KLEGDLKDLELQADSAIKGREEA 1528
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
++L ++ +++ + ++ A E+ K KSLE
Sbjct: 1529 IKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1571
Score = 42.3 bits (95), Expect = 0.002
Identities = 50/235 (21%), Positives = 102/235 (43%), Gaps = 11/235 (4%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADT----CEQQARDANLRAEKVNEEVRELQK-- 210
Q + T +A KK++ L D+ +K E++ D + E+ + L K
Sbjct: 855 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLK 914
Query: 211 -KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAE----VAALNRKVQQIEEDLEKSE 375
K + +L + K E++ ++LE+ +++L ++ +A L ++ +++ L K E
Sbjct: 915 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 974
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
E A +L + + A +NN + K+ E E + L L R A+ +
Sbjct: 975 EELQAALARLDD--EIAQKNNALKKIREL-----EGHISDLQEDLDSERAARNKAEKQKR 1027
Query: 556 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
++ +L ++ ELE D + ++ E+E+ V+ +L S E Q +
Sbjct: 1028 DLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEM 1082
Score = 40.7 bits (91), Expect = 0.005
Identities = 41/180 (22%), Positives = 79/180 (43%), Gaps = 7/180 (3%)
Frame = +1
Query: 190 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 369
+V ++++ E++L K + ++A +L+E E++ + E L ++Q E +
Sbjct: 731 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 790
Query: 370 SEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQ---DEERMDQ----LTNQLKEARLL 528
+EE K E ++ E + E+R QQ + ++M Q L QL+E
Sbjct: 791 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 850
Query: 529 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
+ + K+ +EDE+ V +D+ + LEE + + +L EEKA
Sbjct: 851 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEER---ISDLTTNLAEEEEKA 907
Score = 38.7 bits (86), Expect = 0.021
Identities = 33/129 (25%), Positives = 65/129 (50%), Gaps = 1/129 (0%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++K A ++K+K + +K D+ EQ +AEK N V++L+++L + E
Sbjct: 1720 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE----QAEKGNARVKQLKRQLEEAE 1775
Query: 229 ED-LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
E+ +N N+ + ++L+E + A EV AL K+++ E RSG +++
Sbjct: 1776 EESQRINANR-RKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSG--GRRV 1832
Query: 406 LEAQQSADE 432
+E ++E
Sbjct: 1833 IENADGSEE 1841
>AB210009-1|BAE06091.1| 1258|Homo sapiens PPFIA2 variant protein
protein.
Length = 1258
Score = 55.6 bits (128), Expect = 2e-07
Identities = 44/181 (24%), Positives = 82/181 (45%), Gaps = 4/181 (2%)
Frame = +1
Query: 187 EEVRELQK-KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 363
+E+ E Q ++AQ++E L +++ + ++ E K L TE R +++
Sbjct: 285 QELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQK 344
Query: 364 EKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDE---ERMDQLTNQLKEARLLAE 534
E EER T +++ L AQ+ + + M LEN E +M++ QL+E LAE
Sbjct: 345 EDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAE 404
Query: 535 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
++ + L VE EL + + + +EE ++ + L+ ++A Q
Sbjct: 405 QKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQ 464
Query: 715 R 717
R
Sbjct: 465 R 465
Score = 46.8 bits (106), Expect = 8e-05
Identities = 42/165 (25%), Positives = 82/165 (49%), Gaps = 2/165 (1%)
Frame = +1
Query: 103 LEKDNAMDKADTCEQQARDANLRAEKVNEE--VRELQKKLAQVEEDLILNKNKLEQANKD 276
LEK + ++ + L E N+E +R++++K Q++E L L + KL+Q +
Sbjct: 354 LEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMR- 412
Query: 277 LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 456
K + L EAE+A Q+I L K+EER G ++++ + +E N+ +
Sbjct: 413 ---KAETLPEVEAELA------QRIAA-LTKAEERHGNIEERMRHLEGQLEEKNQELQRA 462
Query: 457 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 591
R + +EE +L++ + RLL E + + ++A +E++
Sbjct: 463 RQREKMNEEHNKRLSDTVD--RLLTESNERLQLHLKERMAALEEK 505
Score = 37.9 bits (84), Expect = 0.036
Identities = 40/189 (21%), Positives = 77/189 (40%), Gaps = 13/189 (6%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 246
M +K+++ A+ +A+T + K ++RE + +EE +
Sbjct: 295 MAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDMEERITTL 354
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+ + A ++ E E+A ++Q+EE + +ER A+QKL + + A
Sbjct: 355 EKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKA 414
Query: 427 DE--------NNRMCKV--LENRAQQDEERMDQLTNQLKEAR---LLAEDADGKSDEVSR 567
+ R+ + E R EERM L QL+E A + ++E ++
Sbjct: 415 ETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNK 474
Query: 568 KLAFVEDEL 594
+L+ D L
Sbjct: 475 RLSDTVDRL 483
>AB177860-1|BAD66838.1| 1715|Homo sapiens KIAA0216 splice variant 2
protein.
Length = 1715
Score = 55.6 bits (128), Expect = 2e-07
Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 7/179 (3%)
Frame = +1
Query: 208 KKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI-------EEDLE 366
K A + ++ KN+LE++ K A E E+ L+ ++ I EE L
Sbjct: 1352 KNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLS 1411
Query: 367 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 546
+ + Q +L E Q+ +E + K +A +D +++ L QL+EA ++
Sbjct: 1412 RLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQE 1471
Query: 547 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
K + ++ F+E + V + V +AKI ELE L+ +K LE + + +E
Sbjct: 1472 KLQALQSQVEFLEQSM-VDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENME 1529
Score = 53.6 bits (123), Expect = 7e-07
Identities = 52/242 (21%), Positives = 122/242 (50%), Gaps = 18/242 (7%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++ T A K +AM++E ++ + D + + ++ E E+Q +L + +
Sbjct: 1369 EESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQ 1428
Query: 229 EDL--ILNKNK--LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE------- 375
ED+ ++ K+K + QA++DL Q+ +A++ N++ Q+++E L+ +
Sbjct: 1429 EDMNELMKKHKAAVAQASRDLA----QINDLQAQLEEANKEKQELQEKLQALQSQVEFLE 1484
Query: 376 ----ERSGTAQQ--KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 537
++S ++Q K+ E + + K LE+ A + +E M++LT + ++ R+ AE+
Sbjct: 1485 QSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEE-RDQRIAAEN 1543
Query: 538 ADGKSDE-VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
+ + ++ + R+L ++E+ + K ELE +L+ + + +SL+ + A +
Sbjct: 1544 REKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFK 1603
Query: 715 RV 720
R+
Sbjct: 1604 RI 1605
Score = 45.2 bits (102), Expect = 2e-04
Identities = 42/198 (21%), Positives = 88/198 (44%), Gaps = 5/198 (2%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
QQ + L E+ N+ R+L+++L ++ D ++ L+Q K + +L T+ +
Sbjct: 1066 QQEFEDKLEVEQQNK--RQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLE 1123
Query: 325 ALNRKVQQIEE-----DLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 489
+ ++E+ D E S+ ++KL + +++ + + + Q +E+ M
Sbjct: 1124 GQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDM 1183
Query: 490 DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVG 669
D K L AE D S E E L + +++ +AK+ + EEEL
Sbjct: 1184 DIAGFTQKVVSLEAELQDISSQESKD-----EASLAKVKKQLRDLEAKVKDQEEELDEQA 1238
Query: 670 NSLKSLEVSEEKANQRVE 723
+++ LE ++ + +E
Sbjct: 1239 GTIQMLEQAKLRLEMEME 1256
Score = 41.1 bits (92), Expect = 0.004
Identities = 52/229 (22%), Positives = 101/229 (44%), Gaps = 11/229 (4%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKL---EKDNAMDKADTCEQQARDANLRAEKVNEEVR-----ELQKKL 216
A++ +KK+++ ++ +++ +D+ Q A LR E E +R E++ +
Sbjct: 1211 ASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRD 1270
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 396
+VEE + KL+Q LEE+ + E L K+ + + + + + S
Sbjct: 1271 EEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRL 1330
Query: 397 QKLLEAQQS-ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 573
+K L+ ++ + M L+N A E + QL NQL+E+ A +RK
Sbjct: 1331 RKDLKRTKALLADAQLMLDHLKNSAPSKRE-IAQLKNQLEESEFTCAAA-----VKARKA 1384
Query: 574 AFVE-DELEVAEDRVKSGDAKISELEEELKVVGNSLKS-LEVSEEKANQ 714
VE ++L + D + + E L+ N +++ LE +E N+
Sbjct: 1385 MEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNE 1433
>AB177858-1|BAD66836.1| 2046|Homo sapiens KIAA0216 splice variant 1
protein.
Length = 2046
Score = 55.6 bits (128), Expect = 2e-07
Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 7/179 (3%)
Frame = +1
Query: 208 KKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI-------EEDLE 366
K A + ++ KN+LE++ K A E E+ L+ ++ I EE L
Sbjct: 1668 KNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLS 1727
Query: 367 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 546
+ + Q +L E Q+ +E + K +A +D +++ L QL+EA ++
Sbjct: 1728 RLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQE 1787
Query: 547 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
K + ++ F+E + V + V +AKI ELE L+ +K LE + + +E
Sbjct: 1788 KLQALQSQVEFLEQSM-VDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENME 1845
Score = 53.6 bits (123), Expect = 7e-07
Identities = 52/242 (21%), Positives = 122/242 (50%), Gaps = 18/242 (7%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++ T A K +AM++E ++ + D + + ++ E E+Q +L + +
Sbjct: 1685 EESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQ 1744
Query: 229 EDL--ILNKNK--LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE------- 375
ED+ ++ K+K + QA++DL Q+ +A++ N++ Q+++E L+ +
Sbjct: 1745 EDMNELMKKHKAAVAQASRDLA----QINDLQAQLEEANKEKQELQEKLQALQSQVEFLE 1800
Query: 376 ----ERSGTAQQ--KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 537
++S ++Q K+ E + + K LE+ A + +E M++LT + ++ R+ AE+
Sbjct: 1801 QSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEE-RDQRIAAEN 1859
Query: 538 ADGKSDE-VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
+ + ++ + R+L ++E+ + K ELE +L+ + + +SL+ + A +
Sbjct: 1860 REKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFK 1919
Query: 715 RV 720
R+
Sbjct: 1920 RI 1921
Score = 45.2 bits (102), Expect = 2e-04
Identities = 42/198 (21%), Positives = 88/198 (44%), Gaps = 5/198 (2%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
QQ + L E+ N+ R+L+++L ++ D ++ L+Q K + +L T+ +
Sbjct: 1382 QQEFEDKLEVEQQNK--RQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLE 1439
Query: 325 ALNRKVQQIEE-----DLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 489
+ ++E+ D E S+ ++KL + +++ + + + Q +E+ M
Sbjct: 1440 GQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDM 1499
Query: 490 DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVG 669
D K L AE D S E E L + +++ +AK+ + EEEL
Sbjct: 1500 DIAGFTQKVVSLEAELQDISSQESKD-----EASLAKVKKQLRDLEAKVKDQEEELDEQA 1554
Query: 670 NSLKSLEVSEEKANQRVE 723
+++ LE ++ + +E
Sbjct: 1555 GTIQMLEQAKLRLEMEME 1572
Score = 41.1 bits (92), Expect = 0.004
Identities = 52/229 (22%), Positives = 101/229 (44%), Gaps = 11/229 (4%)
Frame = +1
Query: 61 ATMDAIKKKMQAMKL---EKDNAMDKADTCEQQARDANLRAEKVNEEVR-----ELQKKL 216
A++ +KK+++ ++ +++ +D+ Q A LR E E +R E++ +
Sbjct: 1527 ASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRD 1586
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 396
+VEE + KL+Q LEE+ + E L K+ + + + + + S
Sbjct: 1587 EEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRL 1646
Query: 397 QKLLEAQQS-ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 573
+K L+ ++ + M L+N A E + QL NQL+E+ A +RK
Sbjct: 1647 RKDLKRTKALLADAQLMLDHLKNSAPSKRE-IAQLKNQLEESEFTCAAA-----VKARKA 1700
Query: 574 AFVE-DELEVAEDRVKSGDAKISELEEELKVVGNSLKS-LEVSEEKANQ 714
VE ++L + D + + E L+ N +++ LE +E N+
Sbjct: 1701 MEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNE 1749
Score = 39.5 bits (88), Expect = 0.012
Identities = 33/141 (23%), Positives = 67/141 (47%), Gaps = 1/141 (0%)
Frame = +1
Query: 148 QARDANLRAE-KVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
+ RD + AE + E+ + LQ++L +E++ E A K+ E K+ E ++
Sbjct: 1849 EERDQRIAAENREKEQNKRLQRQLRDTKEEMG------ELARKEAEASRKK-HELEMDLE 1901
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
+L Q ++ DL+ + +R G Q + E + +DEN + L++ + ++R ++L
Sbjct: 1902 SLEAANQSLQADLKLAFKRIGDLQAAI-EDEMESDENEDLINSLQDMVTKYQKRKNKLEG 1960
Query: 505 QLKEARLLAEDADGKSDEVSR 567
L + DG +S+
Sbjct: 1961 DSDVDSELEDRVDGVKSWLSK 1981
>AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein.
Length = 1984
Score = 55.6 bits (128), Expect = 2e-07
Identities = 55/249 (22%), Positives = 118/249 (47%), Gaps = 16/249 (6%)
Frame = +1
Query: 25 VFNSTGP*QQKAATMDAIKKKMQ-----AMKLEKDNAMDKADTCEQQARDANLRAEKVNE 189
+F + ++KA +++A ++Q A + K ++K + E+ A + R + +
Sbjct: 1683 IFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR-NALQD 1741
Query: 190 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 369
E R L+ ++AQ+EE+L + +E + + + +Q E+A Q+ E ++
Sbjct: 1742 EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ 1801
Query: 370 SEERSGTAQQKLLEAQQSADENNRMC-KVLENRAQQDEERMDQLTNQLKEARLLAEDADG 546
E ++ + KL E + + + LE + Q EE+++Q + + A + D
Sbjct: 1802 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1861
Query: 547 KSDEVSRKLAFVEDELEVAE---DRVKSGDAKISEL-------EEELKVVGNSLKSLEVS 696
K E+ L VEDE ++AE ++ + G+A++ +L EEE + + + + L+
Sbjct: 1862 KLKEI---LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1918
Query: 697 EEKANQRVE 723
++A + E
Sbjct: 1919 LDEATESNE 1927
Score = 54.0 bits (124), Expect = 5e-07
Identities = 38/200 (19%), Positives = 97/200 (48%), Gaps = 5/200 (2%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 1746 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNESA---RQQ 1801
Query: 256 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 1802 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1861
Query: 421 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 600
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 1862 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 1921
Query: 601 AEDRVKSGDAKISELEEELK 660
A + ++ +++ L+ +L+
Sbjct: 1922 ATESNEAMGREVNALKSKLR 1941
Score = 52.0 bits (119), Expect = 2e-06
Identities = 41/223 (18%), Positives = 103/223 (46%), Gaps = 19/223 (8%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 216
+++ A A KKK++ ++L+ D+A+ + +Q R + + E+ + +
Sbjct: 1621 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1680
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS-------E 375
++ N+ K + DL + ++ L A E + + +++ E+L S +
Sbjct: 1681 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ 1740
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
+ + ++ + ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 1741 DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ 1800
Query: 556 EVSRKLAFVEDELEVAEDRVKSG--------DAKISELEEELK 660
++ R+ + +L E VKS +AKI++LEE+++
Sbjct: 1801 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVE 1843
Score = 50.8 bits (116), Expect = 5e-06
Identities = 37/217 (17%), Positives = 92/217 (42%), Gaps = 1/217 (0%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++++ +++ + D M+ E+ N++ +++++ + +EE + +
Sbjct: 1353 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1412
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADE 432
+E + EEK E L +++ + DL+ + ++K + Q A+E
Sbjct: 1413 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1472
Query: 433 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 612
N K + R + + E ++ T L AR L E + K +E+ R ++ E+E
Sbjct: 1473 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSS 1531
Query: 613 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ ELE+ + + ++ ++ E+ ++
Sbjct: 1532 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQ 1568
Score = 49.6 bits (113), Expect = 1e-05
Identities = 51/219 (23%), Positives = 97/219 (44%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++ A D ++K + + ++ + Q + NL E++ E EL + ++
Sbjct: 864 EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEEMR 922
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
L K +LE+ ++E + ++ ++ A +K+ Q DLE+ E A+QKL
Sbjct: 923 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 982
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
+ +A+ K LE+ MD N+L + R L E+ + +++ LA E+
Sbjct: 983 LEKVTAEAK---IKKLEDEILV----MDDQNNKLSKERKLLEE---RISDLTTNLAEEEE 1032
Query: 589 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+ + ++ ISELE LK S + LE + K
Sbjct: 1033 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRK 1071
Score = 47.6 bits (108), Expect = 4e-05
Identities = 45/206 (21%), Positives = 88/206 (42%), Gaps = 1/206 (0%)
Frame = +1
Query: 109 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 288
K D A T E + R +K E + + ++ A + L KN+L+Q DL
Sbjct: 1389 KKKLQDFASTVEA-LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1447
Query: 289 EKQLTATEAEVAALNRKVQQI-EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 465
+ + RK Q+ E+ S + + + EA++ + + + LE
Sbjct: 1448 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 1507
Query: 466 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 645
+ EE + TN++ +A + ED D+V + + +E E +++ ++ EL
Sbjct: 1508 LEAKEEL--ERTNKMLKAEM--EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 1563
Query: 646 EEELKVVGNSLKSLEVSEEKANQRVE 723
E+EL+ ++ LEV+ + + E
Sbjct: 1564 EDELQATEDAKLRLEVNMQALKGQFE 1589
Score = 45.6 bits (103), Expect = 2e-04
Identities = 47/223 (21%), Positives = 102/223 (45%), Gaps = 9/223 (4%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 222
++ A +A +K+ +A+ L + + A++ + E+ + E + ++ K + +
Sbjct: 1482 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 1541
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 390
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E++
Sbjct: 1542 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1601
Query: 391 AQQKL---LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 561
+++L L ++ E+ R + L A++ +L LK+ L A+ A +E
Sbjct: 1602 KRRQLQRQLHEYETELEDERKQRALAAAAKK------KLEGDLKDLELQADSAIKGREEA 1655
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
++L ++ +++ + ++ A E+ K KSLE
Sbjct: 1656 IKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1698
Score = 42.3 bits (95), Expect = 0.002
Identities = 50/235 (21%), Positives = 102/235 (43%), Gaps = 11/235 (4%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADT----CEQQARDANLRAEKVNEEVRELQK-- 210
Q + T +A KK++ L D+ +K E++ D + E+ + L K
Sbjct: 982 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLK 1041
Query: 211 -KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAE----VAALNRKVQQIEEDLEKSE 375
K + +L + K E++ ++LE+ +++L ++ +A L ++ +++ L K E
Sbjct: 1042 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1101
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
E A +L + + A +NN + K+ E E + L L R A+ +
Sbjct: 1102 EELQAALARLDD--EIAQKNNALKKIREL-----EGHISDLQEDLDSERAARNKAEKQKR 1154
Query: 556 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
++ +L ++ ELE D + ++ E+E+ V+ +L S E Q +
Sbjct: 1155 DLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEM 1209
Score = 40.7 bits (91), Expect = 0.005
Identities = 41/180 (22%), Positives = 79/180 (43%), Gaps = 7/180 (3%)
Frame = +1
Query: 190 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 369
+V ++++ E++L K + ++A +L+E E++ + E L ++Q E +
Sbjct: 858 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 917
Query: 370 SEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQ---DEERMDQ----LTNQLKEARLL 528
+EE K E ++ E + E+R QQ + ++M Q L QL+E
Sbjct: 918 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 977
Query: 529 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
+ + K+ +EDE+ V +D+ + LEE + + +L EEKA
Sbjct: 978 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEER---ISDLTTNLAEEEEKA 1034
Score = 38.7 bits (86), Expect = 0.021
Identities = 33/129 (25%), Positives = 65/129 (50%), Gaps = 1/129 (0%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
++K A ++K+K + +K D+ EQ +AEK N V++L+++L + E
Sbjct: 1847 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE----QAEKGNARVKQLKRQLEEAE 1902
Query: 229 ED-LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 405
E+ +N N+ + ++L+E + A EV AL K+++ E RSG +++
Sbjct: 1903 EESQRINANR-RKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSG--GRRV 1959
Query: 406 LEAQQSADE 432
+E ++E
Sbjct: 1960 IENADGSEE 1968
>AB015346-1|BAA88118.1| 864|Homo sapiens Eps15R protein.
Length = 864
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/144 (21%), Positives = 68/144 (47%)
Frame = +1
Query: 292 KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 471
K+L E+A L R+ +E+D+ + EE ++ E Q D + LE + Q
Sbjct: 384 KELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQ 443
Query: 472 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE 651
++R+D++ Q + R + D K + ++ ++ ++ +++ E +KS + ++ +
Sbjct: 444 DAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKS 503
Query: 652 ELKVVGNSLKSLEVSEEKANQRVE 723
EL + LE S + ++E
Sbjct: 504 ELNRLQQEETQLEQSIQAGRVQLE 527
>Z98946-1|CAB46379.1| 577|Homo sapiens moesin protein.
Length = 577
Score = 55.2 bits (127), Expect = 2e-07
Identities = 66/245 (26%), Positives = 117/245 (47%), Gaps = 20/245 (8%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADT-CEQQARD-ANLRAEKVNEEVRELQKKLAQ 222
++K T++ + K QA + + M++A E++ R+ A EK+ E EL ++L Q
Sbjct: 294 RRKPDTIEVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQ 353
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEED----LEKSEERSGT 390
+EE + +LE+ + E E++ ++E L ++ Q+ EE L+ S ++ T
Sbjct: 354 IEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKT 413
Query: 391 AQQKLLE-----AQQSADENNRMCKVLE-----NRAQQDEERMDQLTNQLKEARL---LA 531
+Q LE A+ S E R K E +AQ +E +++ +LK A +A
Sbjct: 414 QEQLALEMAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPHVA 473
Query: 532 EDADGKSDEVSRKLAFVEDELEV-AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
E A+ + DE A +L A + +S + + +E E+ + V LK+L + E A
Sbjct: 474 EPAENEQDEQDENGAEASADLRADAMAKDRSEEERTTEAEKNER-VQKHLKAL--TSELA 530
Query: 709 NQRVE 723
N R E
Sbjct: 531 NARDE 535
>U80458-1|AAD00355.1| 1604|Homo sapiens microtubule associated protein
1A protein.
Length = 1604
Score = 55.2 bits (127), Expect = 2e-07
Identities = 55/200 (27%), Positives = 97/200 (48%), Gaps = 4/200 (2%)
Frame = +1
Query: 103 LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 282
LE ++ DT Q +D L + NE V++ K L Q DL LEQ +K LE
Sbjct: 1291 LEHKEVVEPKDTAIYQ-KDEALHVK--NEAVKQQDKALEQKGRDLEQKDTALEQKDKALE 1347
Query: 283 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN-NRMCKVLE 459
K+K L E + AL +K +I E+ +K+ E+ TA ++ + + D++ + +VLE
Sbjct: 1348 PKDKDL---EEKDKALEQK-DKIPEEKDKALEQKDTALEQKDKTLEPKDKDLEQKDRVLE 1403
Query: 460 NRAQQDEERMDQLTNQLKEARLLA-ED--ADGKSDEVSRKLAFVEDELEVAEDRVKSGDA 630
+ + EE+ L +++ A ED A+ K ++ + E + + E + K +
Sbjct: 1404 QKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEK 1463
Query: 631 KISELEEELKVVGNSLKSLE 690
K LE++ +G ++LE
Sbjct: 1464 KDQALEQKYWALGQKDEALE 1483
Score = 53.2 bits (122), Expect = 9e-07
Identities = 53/212 (25%), Positives = 105/212 (49%), Gaps = 6/212 (2%)
Frame = +1
Query: 106 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEE 285
EKD A+++ D ++ +D L E+ + + + K L ++DL LEQ K EE
Sbjct: 1355 EKDKALEQKDKIPEE-KDKAL--EQKDTALEQKDKTLEPKDKDLEQKDRVLEQKEKIPEE 1411
Query: 286 KEKQLTATEAEVAALNRKVQQ--IEEDLEKSEERSGTAQQKLLEAQQSADE-NNRMCKVL 456
K+K A + +V ++ K + + E ++ E++ A ++ +AQ+ D+ + + + L
Sbjct: 1412 KDK---ALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQAL 1468
Query: 457 ENR---AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 627
E + Q +E ++Q L+E E ++ +RK +E E + ++VK+ +
Sbjct: 1469 EQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLE---EKSPEKVKAME 1525
Query: 628 AKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
K+ L E+ K +G L+ V E +A ++ E
Sbjct: 1526 EKLEALLEKTKALG--LEESLVQEGRAREQEE 1555
Score = 38.3 bits (85), Expect = 0.028
Identities = 33/149 (22%), Positives = 73/149 (48%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 249
D + ++ + + EKD A+D Q+ R +A + + V E++ + + + K
Sbjct: 1399 DRVLEQKEKIPEEKDKALD------QKVRSVEHKAPE--DTVAEMKDRDLEQTDKAPEQK 1450
Query: 250 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 429
++ ++ + EK+ Q A E + AL +K + +E++++ EE T +Q+ L +
Sbjct: 1451 HQAQEQKDKVSEKKDQ--ALEQKYWALGQKDEALEQNIQALEENHQTQEQESL----VQE 1504
Query: 430 ENNRMCKVLENRAQQDEERMDQLTNQLKE 516
+ R K+LE ++ + + M++ L E
Sbjct: 1505 DKTRKPKMLEEKSPEKVKAMEEKLEALLE 1533
>M69066-1|AAA36322.1| 577|Homo sapiens moesin B protein.
Length = 577
Score = 55.2 bits (127), Expect = 2e-07
Identities = 66/245 (26%), Positives = 117/245 (47%), Gaps = 20/245 (8%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADT-CEQQARD-ANLRAEKVNEEVRELQKKLAQ 222
++K T++ + K QA + + M++A E++ R+ A EK+ E EL ++L Q
Sbjct: 294 RRKPDTIEVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQ 353
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEED----LEKSEERSGT 390
+EE + +LE+ + E E++ ++E L ++ Q+ EE L+ S ++ T
Sbjct: 354 IEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKT 413
Query: 391 AQQKLLE-----AQQSADENNRMCKVLE-----NRAQQDEERMDQLTNQLKEARL---LA 531
+Q LE A+ S E R K E +AQ +E +++ +LK A +A
Sbjct: 414 QEQLALEMAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPHVA 473
Query: 532 EDADGKSDEVSRKLAFVEDELEV-AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
E A+ + DE A +L A + +S + + +E E+ + V LK+L + E A
Sbjct: 474 EPAENEQDEQDENGAEASADLRADAMAKDRSEEERTTEAEKNER-VQKHLKAL--TSELA 530
Query: 709 NQRVE 723
N R E
Sbjct: 531 NARDE 535
>M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 55.2 bits (127), Expect = 2e-07
Identities = 57/230 (24%), Positives = 114/230 (49%), Gaps = 14/230 (6%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 243
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 1526 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 1582
Query: 244 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 411
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 1583 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1638
Query: 412 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 564
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 1639 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1698
Query: 565 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
RKLA E EL +RV+ ++ + L + K + L L+ E+A Q
Sbjct: 1699 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQ 1746
Score = 54.8 bits (126), Expect = 3e-07
Identities = 55/227 (24%), Positives = 105/227 (46%), Gaps = 15/227 (6%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 246
++K+ KLE D+ + + + + +++ E + K + + DL
Sbjct: 1217 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 1276
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTAQQKLLEA 414
+ KL+ N +L +QL EA ++ L R QQ+ EDL++ E A+ L A
Sbjct: 1277 RAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKAKNALAHA 1332
Query: 415 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRK 570
QSA + C +L + +++ E +L L +A +A+ DA +++E+
Sbjct: 1333 LQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 1389
Query: 571 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
+ L+ AE+ V++ +AK S LE+ + N ++ L V E++N
Sbjct: 1390 KKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/203 (21%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 502 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISEL 645
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Query: 646 EEELKVVGNSLKSLEVSEEKANQ 714
+ E + +L+ + E N+
Sbjct: 1602 DAETRSRNEALRVKKKMEGDLNE 1624
Score = 53.6 bits (123), Expect = 7e-07
Identities = 54/221 (24%), Positives = 100/221 (45%), Gaps = 7/221 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+++ +A+ +Q+ + + D ++ + + + K N EV + + K E
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY---E 1376
Query: 229 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 387
D I +LE+A K L +E E+ + A A+ ++L + +++ EDL ERS
Sbjct: 1377 TDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
A L + Q++ D K+L Q+ EE +L + KEAR L+ + +
Sbjct: 1437 AAAAALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 1490
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
L + LE + K+ +IS+L E+L G ++ LE
Sbjct: 1491 SL----EHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 1527
Score = 50.8 bits (116), Expect = 5e-06
Identities = 49/215 (22%), Positives = 105/215 (48%), Gaps = 12/215 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQ----AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 216
++ A + A K+K++ +K + D+ E++ + + + EE+ L + +
Sbjct: 930 EEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 989
Query: 217 AQVEEDLILNKNKLEQANKDLE-EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 393
A++ ++ + +QA DL+ E++K T T+A+V K++Q +DLE S E+
Sbjct: 990 AKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKV-----KLEQQVDDLEGSLEQEKKV 1044
Query: 394 QQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 561
+ L A++ + + ++ + LEN QQ +ER+ + +L ED ++
Sbjct: 1045 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 1104
Query: 562 SRKLAFVEDELEVAEDRVKS---GDAKISELEEEL 657
+KL ++ +E E+ ++S AK+ +L +L
Sbjct: 1105 QKKLKELQARIEELEEELESERTARAKVEKLRSDL 1139
Score = 50.4 bits (115), Expect = 6e-06
Identities = 62/260 (23%), Positives = 116/260 (44%), Gaps = 35/260 (13%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEV 195
++K ++ K +Q ++ E+DN D + C+Q + ++ N R E E
Sbjct: 874 EEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 933
Query: 196 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK-S 372
EL K ++E++ K ++ L + EK+ ATE +V L ++ ++E + K +
Sbjct: 934 AELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 993
Query: 373 EERSG---TAQQKLLEAQQSADENNRMCKV----------LENRAQQDEE-RMD------ 492
+E+ QQ L + Q D+ N + K LE +Q+++ RMD
Sbjct: 994 KEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKR 1053
Query: 493 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 672
+L LK + D + ++ +L + EL R++ A S+L+++LK +
Sbjct: 1054 KLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQA 1113
Query: 673 SLKSLE---VSEEKANQRVE 723
++ LE SE A +VE
Sbjct: 1114 RIEELEEELESERTARAKVE 1133
Score = 46.8 bits (106), Expect = 8e-05
Identities = 33/153 (21%), Positives = 72/153 (47%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
QQA D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 1004 QQALD-DLQAEE--DKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1060
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
+ +E D ++ +ER +L ++ + L+ + ++ + R+++L
Sbjct: 1061 LTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEE 1120
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 603
+L+ R + ++SR+L + + LE A
Sbjct: 1121 ELESERTARAKVEKLRSDLSRELEEISERLEEA 1153
Score = 44.4 bits (100), Expect = 4e-04
Identities = 36/149 (24%), Positives = 72/149 (48%), Gaps = 7/149 (4%)
Frame = +1
Query: 283 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 462
E+EK++ A++ + +++E LEKSE R ++K++ Q ++ + ++
Sbjct: 844 EREKEM-------ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 896
Query: 463 RAQQDEERMDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 621
EER DQL ++KE ED + + E++ K +EDE + +
Sbjct: 897 NLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDD 956
Query: 622 GDAKISELEEELKVVGNSLKSLEVSEEKA 708
+ ++++E+E N +K+L +EE A
Sbjct: 957 LELTLAKVEKEKHATENKVKNL--TEEMA 983
Score = 37.1 bits (82), Expect = 0.064
Identities = 41/204 (20%), Positives = 95/204 (46%), Gaps = 13/204 (6%)
Frame = +1
Query: 73 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEV-RELQKKLAQVEE------ 231
A+ ++Q E +++ + + R A + EK+ ++ REL++ ++EE
Sbjct: 1099 ALGSQLQKKLKELQARIEELEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATS 1158
Query: 232 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQ 396
+ +NK + + K + E+ EA AAL +K V ++ E ++ + +
Sbjct: 1159 VQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 1218
Query: 397 QKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 573
++ E + D+ + M ++++ +A E+ L +Q+ E R AE+ ++++ +
Sbjct: 1219 KEKSEFKLELDDVTSNMEQIIKAKANL-EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277
Query: 574 AFVEDELEVAEDRVKSGDAKISEL 645
A ++ E ++ +A IS+L
Sbjct: 1278 AKLQTENGELSRQLDEKEALISQL 1301
>M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 55.2 bits (127), Expect = 2e-07
Identities = 57/230 (24%), Positives = 114/230 (49%), Gaps = 14/230 (6%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 243
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 1526 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 1582
Query: 244 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 411
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 1583 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1638
Query: 412 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 564
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 1639 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1698
Query: 565 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
RKLA E EL +RV+ ++ + L + K + L L+ E+A Q
Sbjct: 1699 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQ 1746
Score = 54.8 bits (126), Expect = 3e-07
Identities = 55/227 (24%), Positives = 105/227 (46%), Gaps = 15/227 (6%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 246
++K+ KLE D+ + + + + +++ E + K + + DL
Sbjct: 1217 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 1276
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTAQQKLLEA 414
+ KL+ N +L +QL EA ++ L R QQ+ EDL++ E A+ L A
Sbjct: 1277 RAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKAKNALAHA 1332
Query: 415 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRK 570
QSA + C +L + +++ E +L L +A +A+ DA +++E+
Sbjct: 1333 LQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 1389
Query: 571 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
+ L+ AE+ V++ +AK S LE+ + N ++ L V E++N
Sbjct: 1390 KKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/203 (21%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 502 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISEL 645
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Query: 646 EEELKVVGNSLKSLEVSEEKANQ 714
+ E + +L+ + E N+
Sbjct: 1602 DAETRSRNEALRVKKKMEGDLNE 1624
Score = 53.6 bits (123), Expect = 7e-07
Identities = 54/221 (24%), Positives = 100/221 (45%), Gaps = 7/221 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+++ +A+ +Q+ + + D ++ + + + K N EV + + K E
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY---E 1376
Query: 229 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 387
D I +LE+A K L +E E+ + A A+ ++L + +++ EDL ERS
Sbjct: 1377 TDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
A L + Q++ D K+L Q+ EE +L + KEAR L+ + +
Sbjct: 1437 AAAAALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 1490
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
L + LE + K+ +IS+L E+L G ++ LE
Sbjct: 1491 SL----EHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 1527
Score = 50.8 bits (116), Expect = 5e-06
Identities = 49/215 (22%), Positives = 105/215 (48%), Gaps = 12/215 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQ----AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 216
++ A + A K+K++ +K + D+ E++ + + + EE+ L + +
Sbjct: 930 EEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 989
Query: 217 AQVEEDLILNKNKLEQANKDLE-EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 393
A++ ++ + +QA DL+ E++K T T+A+V K++Q +DLE S E+
Sbjct: 990 AKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKV-----KLEQQVDDLEGSLEQEKKV 1044
Query: 394 QQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 561
+ L A++ + + ++ + LEN QQ +ER+ + +L ED ++
Sbjct: 1045 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 1104
Query: 562 SRKLAFVEDELEVAEDRVKS---GDAKISELEEEL 657
+KL ++ +E E+ ++S AK+ +L +L
Sbjct: 1105 QKKLKELQARIEELEEELESERTARAKVEKLRSDL 1139
Score = 50.4 bits (115), Expect = 6e-06
Identities = 62/260 (23%), Positives = 116/260 (44%), Gaps = 35/260 (13%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEV 195
++K ++ K +Q ++ E+DN D + C+Q + ++ N R E E
Sbjct: 874 EEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 933
Query: 196 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK-S 372
EL K ++E++ K ++ L + EK+ ATE +V L ++ ++E + K +
Sbjct: 934 AELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 993
Query: 373 EERSG---TAQQKLLEAQQSADENNRMCKV----------LENRAQQDEE-RMD------ 492
+E+ QQ L + Q D+ N + K LE +Q+++ RMD
Sbjct: 994 KEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKR 1053
Query: 493 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 672
+L LK + D + ++ +L + EL R++ A S+L+++LK +
Sbjct: 1054 KLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQA 1113
Query: 673 SLKSLE---VSEEKANQRVE 723
++ LE SE A +VE
Sbjct: 1114 RIEELEEELESERTARAKVE 1133
Score = 46.8 bits (106), Expect = 8e-05
Identities = 33/153 (21%), Positives = 72/153 (47%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
QQA D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 1004 QQALD-DLQAEE--DKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1060
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
+ +E D ++ +ER +L ++ + L+ + ++ + R+++L
Sbjct: 1061 LTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEE 1120
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 603
+L+ R + ++SR+L + + LE A
Sbjct: 1121 ELESERTARAKVEKLRSDLSRELEEISERLEEA 1153
Score = 44.4 bits (100), Expect = 4e-04
Identities = 36/149 (24%), Positives = 72/149 (48%), Gaps = 7/149 (4%)
Frame = +1
Query: 283 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 462
E+EK++ A++ + +++E LEKSE R ++K++ Q ++ + ++
Sbjct: 844 EREKEM-------ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 896
Query: 463 RAQQDEERMDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 621
EER DQL ++KE ED + + E++ K +EDE + +
Sbjct: 897 NLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDD 956
Query: 622 GDAKISELEEELKVVGNSLKSLEVSEEKA 708
+ ++++E+E N +K+L +EE A
Sbjct: 957 LELTLAKVEKEKHATENKVKNL--TEEMA 983
Score = 37.1 bits (82), Expect = 0.064
Identities = 41/204 (20%), Positives = 95/204 (46%), Gaps = 13/204 (6%)
Frame = +1
Query: 73 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEV-RELQKKLAQVEE------ 231
A+ ++Q E +++ + + R A + EK+ ++ REL++ ++EE
Sbjct: 1099 ALGSQLQKKLKELQARIEELEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATS 1158
Query: 232 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQ 396
+ +NK + + K + E+ EA AAL +K V ++ E ++ + +
Sbjct: 1159 VQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 1218
Query: 397 QKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 573
++ E + D+ + M ++++ +A E+ L +Q+ E R AE+ ++++ +
Sbjct: 1219 KEKSEFKLELDDVTSNMEQIIKAKANL-EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277
Query: 574 AFVEDELEVAEDRVKSGDAKISEL 645
A ++ E ++ +A IS+L
Sbjct: 1278 AKLQTENGELSRQLDEKEALISQL 1301
>EF560725-1|ABQ59035.1| 1934|Homo sapiens MYH7 protein protein.
Length = 1934
Score = 55.2 bits (127), Expect = 2e-07
Identities = 57/230 (24%), Positives = 114/230 (49%), Gaps = 14/230 (6%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 243
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 1525 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 1581
Query: 244 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 411
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 1582 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1637
Query: 412 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 564
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 1638 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1697
Query: 565 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
RKL VE EL +RV+ ++ + L + K + L L+ E+A Q
Sbjct: 1698 RKL--VEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQ 1745
Score = 54.8 bits (126), Expect = 3e-07
Identities = 55/227 (24%), Positives = 105/227 (46%), Gaps = 15/227 (6%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 246
++K+ KLE D+ + + + + +++ E + K + + DL
Sbjct: 1216 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 1275
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTAQQKLLEA 414
+ KL+ N +L +QL EA ++ L R QQ+ EDL++ E A+ L A
Sbjct: 1276 RAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKAKNALAHA 1331
Query: 415 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRK 570
QSA + C +L + +++ E +L L +A +A+ DA +++E+
Sbjct: 1332 LQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 1388
Query: 571 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
+ L+ AE+ V++ +AK S LE+ + N ++ L V E++N
Sbjct: 1389 KKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1435
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/203 (21%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1421 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1480
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 1481 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1540
Query: 502 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISEL 645
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 1541 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1600
Query: 646 EEELKVVGNSLKSLEVSEEKANQ 714
+ E + +L+ + E N+
Sbjct: 1601 DAETRSRNEALRVKKKMEGDLNE 1623
Score = 53.6 bits (123), Expect = 7e-07
Identities = 54/221 (24%), Positives = 100/221 (45%), Gaps = 7/221 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+++ +A+ +Q+ + + D ++ + + + K N EV + + K E
Sbjct: 1319 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY---E 1375
Query: 229 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 387
D I +LE+A K L +E E+ + A A+ ++L + +++ EDL ERS
Sbjct: 1376 TDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1435
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
A L + Q++ D K+L Q+ EE +L + KEAR L+ + +
Sbjct: 1436 AAAAALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 1489
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
L + LE + K+ +IS+L E+L G ++ LE
Sbjct: 1490 SL----EHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 1526
Score = 50.8 bits (116), Expect = 5e-06
Identities = 49/230 (21%), Positives = 102/230 (44%), Gaps = 15/230 (6%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 258
K K +LE + M+ T ++ R ++ ++ +L+ LA+VE++ +NK+
Sbjct: 917 KVKEMNERLEDEEEMNAELTAKK--RKLEDECSELKRDIDDLELTLAKVEKEKHATENKV 974
Query: 259 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 438
+ +++ ++ + E AL QQ +DL+ E++ T + ++ +Q D+
Sbjct: 975 KNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLE 1034
Query: 439 RMCKVLENRAQQDEERMDQ-LTNQLKEARLLAEDADGKSDEVSRKL-----------AFV 582
+ E + + D ER + L LK + D + ++ +L A +
Sbjct: 1035 GSLEQ-EKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARI 1093
Query: 583 EDELEVA---EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
EDE + + ++K A+I ELEEEL+ + +E ++ +E
Sbjct: 1094 EDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELE 1143
Score = 50.0 bits (114), Expect = 8e-06
Identities = 48/215 (22%), Positives = 105/215 (48%), Gaps = 12/215 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQ----AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 216
++ A + A K+K++ +K + D+ E++ + + + EE+ L + +
Sbjct: 929 EEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 988
Query: 217 AQVEEDLILNKNKLEQANKDLE-EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 393
A++ ++ + +QA DL+ E++K T T+A+V K++Q +DLE S E+
Sbjct: 989 AKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKV-----KLEQQVDDLEGSLEQEKKV 1043
Query: 394 QQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 561
+ L A++ + + ++ + LEN QQ +ER+ + +L ED ++
Sbjct: 1044 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 1103
Query: 562 SRKLAFVEDELEVAEDRV---KSGDAKISELEEEL 657
+KL ++ +E E+ + ++ AK+ +L +L
Sbjct: 1104 QKKLKELQARIEELEEELEAERTARAKVEKLRSDL 1138
Score = 49.2 bits (112), Expect = 1e-05
Identities = 49/233 (21%), Positives = 101/233 (43%), Gaps = 13/233 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEV 195
++K ++ K +Q ++ E+DN D + C+Q + ++ N R E E
Sbjct: 873 EEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 932
Query: 196 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 375
EL K ++E++ K ++ L + EK+ ATE +V L ++ ++E + K
Sbjct: 933 AELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 992
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
+ Q+ +A L + E+++D L L++ + + D +
Sbjct: 993 KEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL----E 1048
Query: 556 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSL--EVSEEKA 708
RKL E +L++ ++ + + +L+E LK L +L + +E+A
Sbjct: 1049 RAKRKL---EGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQA 1098
Score = 46.4 bits (105), Expect = 1e-04
Identities = 33/153 (21%), Positives = 72/153 (47%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
QQA D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 1003 QQALD-DLQAEE--DKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1059
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
+ +E D ++ +ER +L ++ + L+ + ++ + R+++L
Sbjct: 1060 LTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEE 1119
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 603
+L+ R + ++SR+L + + LE A
Sbjct: 1120 ELEAERTARAKVEKLRSDLSRELEEISERLEEA 1152
Score = 44.4 bits (100), Expect = 4e-04
Identities = 36/149 (24%), Positives = 72/149 (48%), Gaps = 7/149 (4%)
Frame = +1
Query: 283 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 462
E+EK++ A++ + +++E LEKSE R ++K++ Q ++ + ++
Sbjct: 843 EREKEM-------ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 895
Query: 463 RAQQDEERMDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 621
EER DQL ++KE ED + + E++ K +EDE + +
Sbjct: 896 NLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDD 955
Query: 622 GDAKISELEEELKVVGNSLKSLEVSEEKA 708
+ ++++E+E N +K+L +EE A
Sbjct: 956 LELTLAKVEKEKHATENKVKNL--TEEMA 982
Score = 36.7 bits (81), Expect = 0.084
Identities = 41/204 (20%), Positives = 95/204 (46%), Gaps = 13/204 (6%)
Frame = +1
Query: 73 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEV-RELQKKLAQVEE------ 231
A+ ++Q E +++ + + R A + EK+ ++ REL++ ++EE
Sbjct: 1098 ALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATS 1157
Query: 232 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQ 396
+ +NK + + K + E+ EA AAL +K V ++ E ++ + +
Sbjct: 1158 VQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 1217
Query: 397 QKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 573
++ E + D+ + M ++++ +A E+ L +Q+ E R AE+ ++++ +
Sbjct: 1218 KEKSEFKLELDDVTSNMEQIIKAKANL-EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1276
Query: 574 AFVEDELEVAEDRVKSGDAKISEL 645
A ++ E ++ +A IS+L
Sbjct: 1277 AKLQTENGELSRQLDEKEALISQL 1300
>EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 55.2 bits (127), Expect = 2e-07
Identities = 57/230 (24%), Positives = 114/230 (49%), Gaps = 14/230 (6%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 243
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 1526 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 1582
Query: 244 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 411
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 1583 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1638
Query: 412 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 564
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 1639 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1698
Query: 565 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
RKLA E EL +RV+ ++ + L + K + L L+ E+A Q
Sbjct: 1699 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQ 1746
Score = 54.8 bits (126), Expect = 3e-07
Identities = 55/227 (24%), Positives = 105/227 (46%), Gaps = 15/227 (6%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 246
++K+ KLE D+ + + + + +++ E + K + + DL
Sbjct: 1217 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 1276
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTAQQKLLEA 414
+ KL+ N +L +QL EA ++ L R QQ+ EDL++ E A+ L A
Sbjct: 1277 RAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKAKNALAHA 1332
Query: 415 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRK 570
QSA + C +L + +++ E +L L +A +A+ DA +++E+
Sbjct: 1333 LQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 1389
Query: 571 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
+ L+ AE+ V++ +AK S LE+ + N ++ L V E++N
Sbjct: 1390 KKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/203 (21%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 502 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISEL 645
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Query: 646 EEELKVVGNSLKSLEVSEEKANQ 714
+ E + +L+ + E N+
Sbjct: 1602 DAETRSRNEALRVKKKMEGDLNE 1624
Score = 53.6 bits (123), Expect = 7e-07
Identities = 54/221 (24%), Positives = 100/221 (45%), Gaps = 7/221 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+++ +A+ +Q+ + + D ++ + + + K N EV + + K E
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY---E 1376
Query: 229 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 387
D I +LE+A K L +E E+ + A A+ ++L + +++ EDL ERS
Sbjct: 1377 TDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
A L + Q++ D K+L Q+ EE +L + KEAR L+ + +
Sbjct: 1437 AAAAALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 1490
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
L + LE + K+ +IS+L E+L G ++ LE
Sbjct: 1491 SL----EHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 1527
Score = 50.8 bits (116), Expect = 5e-06
Identities = 49/230 (21%), Positives = 102/230 (44%), Gaps = 15/230 (6%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 258
K K +LE + M+ T ++ R ++ ++ +L+ LA+VE++ +NK+
Sbjct: 918 KVKEMNERLEDEEEMNAELTAKK--RKLEDECSELKRDIDDLELTLAKVEKEKHATENKV 975
Query: 259 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 438
+ +++ ++ + E AL QQ +DL+ E++ T + ++ +Q D+
Sbjct: 976 KNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLE 1035
Query: 439 RMCKVLENRAQQDEERMDQ-LTNQLKEARLLAEDADGKSDEVSRKL-----------AFV 582
+ E + + D ER + L LK + D + ++ +L A +
Sbjct: 1036 GSLEQ-EKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARI 1094
Query: 583 EDELEVA---EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
EDE + + ++K A+I ELEEEL+ + +E ++ +E
Sbjct: 1095 EDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELE 1144
Score = 50.0 bits (114), Expect = 8e-06
Identities = 48/215 (22%), Positives = 105/215 (48%), Gaps = 12/215 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQ----AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 216
++ A + A K+K++ +K + D+ E++ + + + EE+ L + +
Sbjct: 930 EEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 989
Query: 217 AQVEEDLILNKNKLEQANKDLE-EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 393
A++ ++ + +QA DL+ E++K T T+A+V K++Q +DLE S E+
Sbjct: 990 AKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKV-----KLEQQVDDLEGSLEQEKKV 1044
Query: 394 QQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 561
+ L A++ + + ++ + LEN QQ +ER+ + +L ED ++
Sbjct: 1045 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 1104
Query: 562 SRKLAFVEDELEVAEDRV---KSGDAKISELEEEL 657
+KL ++ +E E+ + ++ AK+ +L +L
Sbjct: 1105 QKKLKELQARIEELEEELEAERTARAKVEKLRSDL 1139
Score = 49.2 bits (112), Expect = 1e-05
Identities = 49/233 (21%), Positives = 101/233 (43%), Gaps = 13/233 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEV 195
++K ++ K +Q ++ E+DN D + C+Q + ++ N R E E
Sbjct: 874 EEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 933
Query: 196 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 375
EL K ++E++ K ++ L + EK+ ATE +V L ++ ++E + K
Sbjct: 934 AELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 993
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
+ Q+ +A L + E+++D L L++ + + D +
Sbjct: 994 KEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL----E 1049
Query: 556 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSL--EVSEEKA 708
RKL E +L++ ++ + + +L+E LK L +L + +E+A
Sbjct: 1050 RAKRKL---EGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQA 1099
Score = 46.4 bits (105), Expect = 1e-04
Identities = 33/153 (21%), Positives = 72/153 (47%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
QQA D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 1004 QQALD-DLQAEE--DKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1060
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
+ +E D ++ +ER +L ++ + L+ + ++ + R+++L
Sbjct: 1061 LTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEE 1120
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 603
+L+ R + ++SR+L + + LE A
Sbjct: 1121 ELEAERTARAKVEKLRSDLSRELEEISERLEEA 1153
Score = 44.4 bits (100), Expect = 4e-04
Identities = 36/149 (24%), Positives = 72/149 (48%), Gaps = 7/149 (4%)
Frame = +1
Query: 283 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 462
E+EK++ A++ + +++E LEKSE R ++K++ Q ++ + ++
Sbjct: 844 EREKEM-------ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 896
Query: 463 RAQQDEERMDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 621
EER DQL ++KE ED + + E++ K +EDE + +
Sbjct: 897 NLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDD 956
Query: 622 GDAKISELEEELKVVGNSLKSLEVSEEKA 708
+ ++++E+E N +K+L +EE A
Sbjct: 957 LELTLAKVEKEKHATENKVKNL--TEEMA 983
Score = 36.7 bits (81), Expect = 0.084
Identities = 41/204 (20%), Positives = 95/204 (46%), Gaps = 13/204 (6%)
Frame = +1
Query: 73 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEV-RELQKKLAQVEE------ 231
A+ ++Q E +++ + + R A + EK+ ++ REL++ ++EE
Sbjct: 1099 ALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATS 1158
Query: 232 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQ 396
+ +NK + + K + E+ EA AAL +K V ++ E ++ + +
Sbjct: 1159 VQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 1218
Query: 397 QKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 573
++ E + D+ + M ++++ +A E+ L +Q+ E R AE+ ++++ +
Sbjct: 1219 KEKSEFKLELDDVTSNMEQIIKAKANL-EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277
Query: 574 AFVEDELEVAEDRVKSGDAKISEL 645
A ++ E ++ +A IS+L
Sbjct: 1278 AKLQTENGELSRQLDEKEALISQL 1301
>BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 55.2 bits (127), Expect = 2e-07
Identities = 57/230 (24%), Positives = 114/230 (49%), Gaps = 14/230 (6%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 243
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 1526 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 1582
Query: 244 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 411
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 1583 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1638
Query: 412 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 564
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 1639 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1698
Query: 565 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
RKLA E EL +RV+ ++ + L + K + L L+ E+A Q
Sbjct: 1699 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQ 1746
Score = 54.8 bits (126), Expect = 3e-07
Identities = 55/227 (24%), Positives = 105/227 (46%), Gaps = 15/227 (6%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 246
++K+ KLE D+ + + + + +++ E + K + + DL
Sbjct: 1217 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 1276
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTAQQKLLEA 414
+ KL+ N +L +QL EA ++ L R QQ+ EDL++ E A+ L A
Sbjct: 1277 RAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKAKNALAHA 1332
Query: 415 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRK 570
QSA + C +L + +++ E +L L +A +A+ DA +++E+
Sbjct: 1333 LQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 1389
Query: 571 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
+ L+ AE+ V++ +AK S LE+ + N ++ L V E++N
Sbjct: 1390 KKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/203 (21%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 502 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISEL 645
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Query: 646 EEELKVVGNSLKSLEVSEEKANQ 714
+ E + +L+ + E N+
Sbjct: 1602 DAETRSRNEALRVKKKMEGDLNE 1624
Score = 53.6 bits (123), Expect = 7e-07
Identities = 54/221 (24%), Positives = 100/221 (45%), Gaps = 7/221 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+++ +A+ +Q+ + + D ++ + + + K N EV + + K E
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY---E 1376
Query: 229 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 387
D I +LE+A K L +E E+ + A A+ ++L + +++ EDL ERS
Sbjct: 1377 TDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
A L + Q++ D K+L Q+ EE +L + KEAR L+ + +
Sbjct: 1437 AAAAALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 1490
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
L + LE + K+ +IS+L E+L G ++ LE
Sbjct: 1491 SL----EHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 1527
Score = 50.8 bits (116), Expect = 5e-06
Identities = 49/230 (21%), Positives = 102/230 (44%), Gaps = 15/230 (6%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 258
K K +LE + M+ T ++ R ++ ++ +L+ LA+VE++ +NK+
Sbjct: 918 KVKEMNERLEDEEEMNAELTAKK--RKLEDECSELKRDIDDLELTLAKVEKEKHATENKV 975
Query: 259 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 438
+ +++ ++ + E AL QQ +DL+ E++ T + ++ +Q D+
Sbjct: 976 KNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLE 1035
Query: 439 RMCKVLENRAQQDEERMDQ-LTNQLKEARLLAEDADGKSDEVSRKL-----------AFV 582
+ E + + D ER + L LK + D + ++ +L A +
Sbjct: 1036 GSLEQ-EKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARI 1094
Query: 583 EDELEVA---EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
EDE + + ++K A+I ELEEEL+ + +E ++ +E
Sbjct: 1095 EDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELE 1144
Score = 50.0 bits (114), Expect = 8e-06
Identities = 48/215 (22%), Positives = 105/215 (48%), Gaps = 12/215 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQ----AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 216
++ A + A K+K++ +K + D+ E++ + + + EE+ L + +
Sbjct: 930 EEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 989
Query: 217 AQVEEDLILNKNKLEQANKDLE-EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 393
A++ ++ + +QA DL+ E++K T T+A+V K++Q +DLE S E+
Sbjct: 990 AKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKV-----KLEQQVDDLEGSLEQEKKV 1044
Query: 394 QQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 561
+ L A++ + + ++ + LEN QQ +ER+ + +L ED ++
Sbjct: 1045 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 1104
Query: 562 SRKLAFVEDELEVAEDRV---KSGDAKISELEEEL 657
+KL ++ +E E+ + ++ AK+ +L +L
Sbjct: 1105 QKKLKELQARIEELEEELEAERTARAKVEKLRSDL 1139
Score = 49.2 bits (112), Expect = 1e-05
Identities = 49/233 (21%), Positives = 101/233 (43%), Gaps = 13/233 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEV 195
++K ++ K +Q ++ E+DN D + C+Q + ++ N R E E
Sbjct: 874 EEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 933
Query: 196 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 375
EL K ++E++ K ++ L + EK+ ATE +V L ++ ++E + K
Sbjct: 934 AELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 993
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
+ Q+ +A L + E+++D L L++ + + D +
Sbjct: 994 KEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL----E 1049
Query: 556 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSL--EVSEEKA 708
RKL E +L++ ++ + + +L+E LK L +L + +E+A
Sbjct: 1050 RAKRKL---EGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQA 1099
Score = 46.4 bits (105), Expect = 1e-04
Identities = 33/153 (21%), Positives = 72/153 (47%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
QQA D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 1004 QQALD-DLQAEE--DKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1060
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
+ +E D ++ +ER +L ++ + L+ + ++ + R+++L
Sbjct: 1061 LTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEE 1120
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 603
+L+ R + ++SR+L + + LE A
Sbjct: 1121 ELEAERTARAKVEKLRSDLSRELEEISERLEEA 1153
Score = 44.4 bits (100), Expect = 4e-04
Identities = 36/149 (24%), Positives = 72/149 (48%), Gaps = 7/149 (4%)
Frame = +1
Query: 283 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 462
E+EK++ A++ + +++E LEKSE R ++K++ Q ++ + ++
Sbjct: 844 EREKEM-------ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 896
Query: 463 RAQQDEERMDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 621
EER DQL ++KE ED + + E++ K +EDE + +
Sbjct: 897 NLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDD 956
Query: 622 GDAKISELEEELKVVGNSLKSLEVSEEKA 708
+ ++++E+E N +K+L +EE A
Sbjct: 957 LELTLAKVEKEKHATENKVKNL--TEEMA 983
Score = 36.7 bits (81), Expect = 0.084
Identities = 41/204 (20%), Positives = 95/204 (46%), Gaps = 13/204 (6%)
Frame = +1
Query: 73 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEV-RELQKKLAQVEE------ 231
A+ ++Q E +++ + + R A + EK+ ++ REL++ ++EE
Sbjct: 1099 ALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATS 1158
Query: 232 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQ 396
+ +NK + + K + E+ EA AAL +K V ++ E ++ + +
Sbjct: 1159 VQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 1218
Query: 397 QKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 573
++ E + D+ + M ++++ +A E+ L +Q+ E R AE+ ++++ +
Sbjct: 1219 KEKSEFKLELDDVTSNMEQIIKAKANL-EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277
Query: 574 AFVEDELEVAEDRVKSGDAKISEL 645
A ++ E ++ +A IS+L
Sbjct: 1278 AKLQTENGELSRQLDEKEALISQL 1301
>BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 55.2 bits (127), Expect = 2e-07
Identities = 57/230 (24%), Positives = 114/230 (49%), Gaps = 14/230 (6%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 243
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 1526 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 1582
Query: 244 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 411
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 1583 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1638
Query: 412 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 564
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 1639 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1698
Query: 565 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
RKLA E EL +RV+ ++ + L + K + L L+ E+A Q
Sbjct: 1699 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQ 1746
Score = 54.8 bits (126), Expect = 3e-07
Identities = 55/227 (24%), Positives = 105/227 (46%), Gaps = 15/227 (6%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 246
++K+ KLE D+ + + + + +++ E + K + + DL
Sbjct: 1217 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 1276
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTAQQKLLEA 414
+ KL+ N +L +QL EA ++ L R QQ+ EDL++ E A+ L A
Sbjct: 1277 RAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKAKNALAHA 1332
Query: 415 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRK 570
QSA + C +L + +++ E +L L +A +A+ DA +++E+
Sbjct: 1333 LQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 1389
Query: 571 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
+ L+ AE+ V++ +AK S LE+ + N ++ L V E++N
Sbjct: 1390 KKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/203 (21%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 502 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISEL 645
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Query: 646 EEELKVVGNSLKSLEVSEEKANQ 714
+ E + +L+ + E N+
Sbjct: 1602 DAETRSRNEALRVKKKMEGDLNE 1624
Score = 53.6 bits (123), Expect = 7e-07
Identities = 54/221 (24%), Positives = 100/221 (45%), Gaps = 7/221 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+++ +A+ +Q+ + + D ++ + + + K N EV + + K E
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY---E 1376
Query: 229 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 387
D I +LE+A K L +E E+ + A A+ ++L + +++ EDL ERS
Sbjct: 1377 TDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
A L + Q++ D K+L Q+ EE +L + KEAR L+ + +
Sbjct: 1437 AAAAALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 1490
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
L + LE + K+ +IS+L E+L G ++ LE
Sbjct: 1491 SL----EHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 1527
Score = 50.8 bits (116), Expect = 5e-06
Identities = 49/230 (21%), Positives = 102/230 (44%), Gaps = 15/230 (6%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 258
K K +LE + M+ T ++ R ++ ++ +L+ LA+VE++ +NK+
Sbjct: 918 KVKEMNERLEDEEEMNAELTAKK--RKLEDECSELKRDIDDLELTLAKVEKEKHATENKV 975
Query: 259 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 438
+ +++ ++ + E AL QQ +DL+ E++ T + ++ +Q D+
Sbjct: 976 KNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLE 1035
Query: 439 RMCKVLENRAQQDEERMDQ-LTNQLKEARLLAEDADGKSDEVSRKL-----------AFV 582
+ E + + D ER + L LK + D + ++ +L A +
Sbjct: 1036 GSLEQ-EKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARI 1094
Query: 583 EDELEVA---EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
EDE + + ++K A+I ELEEEL+ + +E ++ +E
Sbjct: 1095 EDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELE 1144
Score = 50.0 bits (114), Expect = 8e-06
Identities = 48/215 (22%), Positives = 105/215 (48%), Gaps = 12/215 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQ----AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 216
++ A + A K+K++ +K + D+ E++ + + + EE+ L + +
Sbjct: 930 EEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 989
Query: 217 AQVEEDLILNKNKLEQANKDLE-EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 393
A++ ++ + +QA DL+ E++K T T+A+V K++Q +DLE S E+
Sbjct: 990 AKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKV-----KLEQQVDDLEGSLEQEKKV 1044
Query: 394 QQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 561
+ L A++ + + ++ + LEN QQ +ER+ + +L ED ++
Sbjct: 1045 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 1104
Query: 562 SRKLAFVEDELEVAEDRV---KSGDAKISELEEEL 657
+KL ++ +E E+ + ++ AK+ +L +L
Sbjct: 1105 QKKLKELQARIEELEEELEAERTARAKVEKLRSDL 1139
Score = 49.2 bits (112), Expect = 1e-05
Identities = 49/233 (21%), Positives = 101/233 (43%), Gaps = 13/233 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEV 195
++K ++ K +Q ++ E+DN D + C+Q + ++ N R E E
Sbjct: 874 EEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 933
Query: 196 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 375
EL K ++E++ K ++ L + EK+ ATE +V L ++ ++E + K
Sbjct: 934 AELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 993
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
+ Q+ +A L + E+++D L L++ + + D +
Sbjct: 994 KEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL----E 1049
Query: 556 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSL--EVSEEKA 708
RKL E +L++ ++ + + +L+E LK L +L + +E+A
Sbjct: 1050 RAKRKL---EGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQA 1099
Score = 46.4 bits (105), Expect = 1e-04
Identities = 33/153 (21%), Positives = 72/153 (47%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
QQA D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 1004 QQALD-DLQAEE--DKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1060
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
+ +E D ++ +ER +L ++ + L+ + ++ + R+++L
Sbjct: 1061 LTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEE 1120
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 603
+L+ R + ++SR+L + + LE A
Sbjct: 1121 ELEAERTARAKVEKLRSDLSRELEEISERLEEA 1153
Score = 44.4 bits (100), Expect = 4e-04
Identities = 36/149 (24%), Positives = 72/149 (48%), Gaps = 7/149 (4%)
Frame = +1
Query: 283 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 462
E+EK++ A++ + +++E LEKSE R ++K++ Q ++ + ++
Sbjct: 844 EREKEM-------ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 896
Query: 463 RAQQDEERMDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 621
EER DQL ++KE ED + + E++ K +EDE + +
Sbjct: 897 NLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDD 956
Query: 622 GDAKISELEEELKVVGNSLKSLEVSEEKA 708
+ ++++E+E N +K+L +EE A
Sbjct: 957 LELTLAKVEKEKHATENKVKNL--TEEMA 983
Score = 36.7 bits (81), Expect = 0.084
Identities = 41/204 (20%), Positives = 95/204 (46%), Gaps = 13/204 (6%)
Frame = +1
Query: 73 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEV-RELQKKLAQVEE------ 231
A+ ++Q E +++ + + R A + EK+ ++ REL++ ++EE
Sbjct: 1099 ALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATS 1158
Query: 232 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQ 396
+ +NK + + K + E+ EA AAL +K V ++ E ++ + +
Sbjct: 1159 VQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 1218
Query: 397 QKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 573
++ E + D+ + M ++++ +A E+ L +Q+ E R AE+ ++++ +
Sbjct: 1219 KEKSEFKLELDDVTSNMEQIIKAKANL-EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277
Query: 574 AFVEDELEVAEDRVKSGDAKISEL 645
A ++ E ++ +A IS+L
Sbjct: 1278 AKLQTENGELSRQLDEKEALISQL 1301
>BC028423-1|AAH28423.1| 1022|Homo sapiens PMFBP1 protein protein.
Length = 1022
Score = 55.2 bits (127), Expect = 2e-07
Identities = 41/205 (20%), Positives = 97/205 (47%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
+K+ + ++ E +N + C Q + + + +++L K++A +E L+ + +
Sbjct: 656 LKENSRKLEEENENLRAELQCCSTQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQ 715
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
L++A + E+ Q T T+ AL+RK ++DL ++ E+ + QQS +
Sbjct: 716 LDKALQK-EKHYLQTTITKEAYDALSRKSAACQDDLTQALEKLNHVTSETKSLQQSLTQT 774
Query: 436 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 615
LE EERM +L +L++ R ++++ + +KL + ++ + +
Sbjct: 775 QEKKAQLEEEIIAYEERMKKLNTELRKLRGFHQESELEVHAFDKKLEEMSCQVLQWQKQH 834
Query: 616 KSGDAKISELEEELKVVGNSLKSLE 690
++ ++ EE+L+ + +L+
Sbjct: 835 QNDLKMLAAKEEQLREFQEEMAALK 859
Score = 51.2 bits (117), Expect = 4e-06
Identities = 45/213 (21%), Positives = 101/213 (47%), Gaps = 7/213 (3%)
Frame = +1
Query: 100 KLEKDNAMDK--ADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE-DLILNKNKLEQAN 270
KL+K +DK ADT ++ R+ + ++ + +E +VEE L L++ + N
Sbjct: 511 KLQKGLLLDKQKADTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLELSEALRKLEN 570
Query: 271 KDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 450
D E+++ Q T E ++ +N + +I+ + ++ L EA + ++ K
Sbjct: 571 SDKEKRQLQKTVAEQDM-KMNDMLDRIKHQHREQGSIKCKLEEDLQEATKLLEDKREQLK 629
Query: 451 VLENRAQQDEERMDQLTNQLKEA-RLLAEDA---DGKSDEVSRKLAFVEDELEVAEDRVK 618
+ + E ++ L + K+ + L E++ + +++ + +L +LE + ++
Sbjct: 630 KSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCSTQLESSLNKYN 689
Query: 619 SGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+ I +L +E+ + SL SL+ +KA Q+
Sbjct: 690 TSQQVIQDLNKEIALQKESLMSLQAQLDKALQK 722
Score = 46.8 bits (106), Expect = 8e-05
Identities = 57/252 (22%), Positives = 117/252 (46%), Gaps = 36/252 (14%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
IKK ++ ++ +KD+ + + +D + E V+E+ R + K + ++E DL + +
Sbjct: 304 IKKILKHLQEQKDSQCLHVEEYQNLVKDLRVELEAVSEQKRNIMKDMMKLELDLHGLREE 363
Query: 256 ----LEQANKD-------LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 402
+E+ +KD L+E + + T T+ ++ +Q+ +E L++ E++ Q
Sbjct: 364 TSAHIERKDKDITILQCRLQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKLTQVQNS 423
Query: 403 LLEAQQSADENNRMCKVLE---NRAQQDEER----------MDQLTNQLKEA----RLLA 531
LL+ ++ ++ M LE A+QD+ + + +L N L+EA RL
Sbjct: 424 LLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQERLAG 483
Query: 532 E-DADGKSDEVSRKLAFVEDELEVAEDRVKSG---DAK----ISELEEELKVVGNSLKSL 687
E A ++ + + A LE + +++ G D + I EL+ EL+++
Sbjct: 484 EAPAAQQAAQCKEEAALAGCHLEDTQRKLQKGLLLDKQKADTIQELQRELQMLQKESSMA 543
Query: 688 EVSEEKANQRVE 723
E + +RVE
Sbjct: 544 EKEQTSNRKRVE 555
Score = 35.5 bits (78), Expect = 0.19
Identities = 40/217 (18%), Positives = 93/217 (42%), Gaps = 9/217 (4%)
Frame = +1
Query: 52 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 231
Q ++ + + ++++ +K E++ R +K+N E+R+L+ + E
Sbjct: 752 QALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRGFHQESEL 811
Query: 232 DLILNKNKLEQANKDLEEKEKQ-------LTATEAEVAALNRKVQQIEED-LEKSEERSG 387
++ KLE+ + + + +KQ L A E ++ ++ ++E+ LE +E
Sbjct: 812 EVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLREFQEEMAALKENLLEDDKEPCC 871
Query: 388 TAQQKL-LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 564
Q + + + N+++ LE A+Q + ++L NQL+E G+ D +
Sbjct: 872 LPQWSVPKDTCRLYRGNDQIMTNLEQWAKQQKVANEKLGNQLREQVKYIAKLSGEKDHLH 931
Query: 565 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNS 675
+ ++ E + + ++ K K +G S
Sbjct: 932 SVMVHLQQENKKLKKEIEEKKMKAENTRLCTKALGPS 968
Score = 33.5 bits (73), Expect = 0.78
Identities = 38/165 (23%), Positives = 75/165 (45%), Gaps = 10/165 (6%)
Frame = +1
Query: 187 EEVRELQKKLAQV------EEDLILN-KNKLEQANKDLEEKEKQLTATEAEVA---ALNR 336
+E +E QK+L++V ++DLI +NKL +N + E+EK L +A+ A A +R
Sbjct: 233 QEHQETQKRLSEVWQKVSQQDDLIQELRNKLACSNALVLEREKALIKLQADFASCTATHR 292
Query: 337 KVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKE 516
E+ E ++ Q++ +E + K L + E Q N +K+
Sbjct: 293 YPPSSSEECEDIKKILKHLQEQKDSQCLHVEEYQNLVKDLRVELEAVSE---QKRNIMKD 349
Query: 517 ARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE 651
L D G +E S + + ++ + + R++ + +E ++
Sbjct: 350 MMKLELDLHGLREETSAHIERKDKDITILQCRLQELQLEFTETQK 394
>BC017293-1|AAH17293.1| 577|Homo sapiens moesin protein.
Length = 577
Score = 55.2 bits (127), Expect = 2e-07
Identities = 66/245 (26%), Positives = 117/245 (47%), Gaps = 20/245 (8%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADT-CEQQARD-ANLRAEKVNEEVRELQKKLAQ 222
++K T++ + K QA + + M++A E++ R+ A EK+ E EL ++L Q
Sbjct: 294 RRKPDTIEVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQ 353
Query: 223 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEED----LEKSEERSGT 390
+EE + +LE+ + E E++ ++E L ++ Q+ EE L+ S ++ T
Sbjct: 354 IEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKT 413
Query: 391 AQQKLLE-----AQQSADENNRMCKVLE-----NRAQQDEERMDQLTNQLKEARL---LA 531
+Q LE A+ S E R K E +AQ +E +++ +LK A +A
Sbjct: 414 QEQLALEMAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPHVA 473
Query: 532 EDADGKSDEVSRKLAFVEDELEV-AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
E A+ + DE A +L A + +S + + +E E+ + V LK+L + E A
Sbjct: 474 EPAENEQDEQDENGAEASADLRADAMAKDRSEEERTTEAEKNER-VQKHLKAL--TSELA 530
Query: 709 NQRVE 723
N R E
Sbjct: 531 NARDE 535
>AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antigen
MU-RMS-40.7B protein.
Length = 1179
Score = 55.2 bits (127), Expect = 2e-07
Identities = 57/230 (24%), Positives = 114/230 (49%), Gaps = 14/230 (6%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 243
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 770 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 826
Query: 244 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 411
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 827 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 882
Query: 412 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 564
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 883 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 942
Query: 565 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
RKLA E EL +RV+ ++ + L + K + L L+ E+A Q
Sbjct: 943 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQ 990
Score = 54.4 bits (125), Expect = 4e-07
Identities = 55/227 (24%), Positives = 105/227 (46%), Gaps = 15/227 (6%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 246
++K+ KLE D+ + + + + +++ E + K + + DL
Sbjct: 461 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 520
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTAQQKLLEA 414
+ KL+ N +L +QL EA ++ L R QQ+ EDL++ E A+ L A
Sbjct: 521 QAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKAKNALAHA 576
Query: 415 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRK 570
QSA + C +L + +++ E +L L +A +A+ DA +++E+
Sbjct: 577 LQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 633
Query: 571 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
+ L+ AE+ V++ +AK S LE+ + N ++ L V E++N
Sbjct: 634 KKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 680
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/203 (21%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 666 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 725
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 726 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 785
Query: 502 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISEL 645
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 786 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 845
Query: 646 EEELKVVGNSLKSLEVSEEKANQ 714
+ E + +L+ + E N+
Sbjct: 846 DAETRSRNEALRVKKKMEGDLNE 868
Score = 53.6 bits (123), Expect = 7e-07
Identities = 54/221 (24%), Positives = 100/221 (45%), Gaps = 7/221 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+++ +A+ +Q+ + + D ++ + + + K N EV + + K E
Sbjct: 564 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY---E 620
Query: 229 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 387
D I +LE+A K L +E E+ + A A+ ++L + +++ EDL ERS
Sbjct: 621 TDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 680
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
A L + Q++ D K+L Q+ EE +L + KEAR L+ + +
Sbjct: 681 AAAAALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 734
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
L + LE + K+ +IS+L E+L G ++ LE
Sbjct: 735 SL----EHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 771
Score = 50.8 bits (116), Expect = 5e-06
Identities = 49/230 (21%), Positives = 102/230 (44%), Gaps = 15/230 (6%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 258
K K +LE + M+ T ++ R ++ ++ +L+ LA+VE++ +NK+
Sbjct: 162 KVKEMNERLEDEEEMNAELTAKK--RKLEDECSELKRDIDDLELTLAKVEKEKHATENKV 219
Query: 259 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 438
+ +++ ++ + E AL QQ +DL+ E++ T + ++ +Q D+
Sbjct: 220 KNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLE 279
Query: 439 RMCKVLENRAQQDEERMDQ-LTNQLKEARLLAEDADGKSDEVSRKL-----------AFV 582
+ E + + D ER + L LK + D + ++ +L A +
Sbjct: 280 GSLEQ-EKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARI 338
Query: 583 EDELEVA---EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
EDE + + ++K A+I ELEEEL+ + +E ++ +E
Sbjct: 339 EDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELE 388
Score = 50.0 bits (114), Expect = 8e-06
Identities = 48/215 (22%), Positives = 105/215 (48%), Gaps = 12/215 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQ----AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 216
++ A + A K+K++ +K + D+ E++ + + + EE+ L + +
Sbjct: 174 EEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 233
Query: 217 AQVEEDLILNKNKLEQANKDLE-EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 393
A++ ++ + +QA DL+ E++K T T+A+V K++Q +DLE S E+
Sbjct: 234 AKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKV-----KLEQQVDDLEGSLEQEKKV 288
Query: 394 QQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 561
+ L A++ + + ++ + LEN QQ +ER+ + +L ED ++
Sbjct: 289 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 348
Query: 562 SRKLAFVEDELEVAEDRV---KSGDAKISELEEEL 657
+KL ++ +E E+ + ++ AK+ +L +L
Sbjct: 349 QKKLKELQARIEELEEELEAERTARAKVEKLRSDL 383
Score = 49.2 bits (112), Expect = 1e-05
Identities = 49/233 (21%), Positives = 101/233 (43%), Gaps = 13/233 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEV 195
++K ++ K +Q ++ E+DN D + C+Q + ++ N R E E
Sbjct: 118 EEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 177
Query: 196 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 375
EL K ++E++ K ++ L + EK+ ATE +V L ++ ++E + K
Sbjct: 178 AELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 237
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
+ Q+ +A L + E+++D L L++ + + D +
Sbjct: 238 KEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL----E 293
Query: 556 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSL--EVSEEKA 708
RKL E +L++ ++ + + +L+E LK L +L + +E+A
Sbjct: 294 RAKRKL---EGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQA 343
Score = 46.4 bits (105), Expect = 1e-04
Identities = 33/153 (21%), Positives = 72/153 (47%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
QQA D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 248 QQALD-DLQAEE--DKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 304
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
+ +E D ++ +ER +L ++ + L+ + ++ + R+++L
Sbjct: 305 LTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEE 364
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 603
+L+ R + ++SR+L + + LE A
Sbjct: 365 ELEAERTARAKVEKLRSDLSRELEEISERLEEA 397
Score = 44.4 bits (100), Expect = 4e-04
Identities = 36/149 (24%), Positives = 72/149 (48%), Gaps = 7/149 (4%)
Frame = +1
Query: 283 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 462
E+EK++ A++ + +++E LEKSE R ++K++ Q ++ + ++
Sbjct: 88 EREKEM-------ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 140
Query: 463 RAQQDEERMDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 621
EER DQL ++KE ED + + E++ K +EDE + +
Sbjct: 141 NLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDD 200
Query: 622 GDAKISELEEELKVVGNSLKSLEVSEEKA 708
+ ++++E+E N +K+L +EE A
Sbjct: 201 LELTLAKVEKEKHATENKVKNL--TEEMA 227
Score = 36.7 bits (81), Expect = 0.084
Identities = 41/204 (20%), Positives = 95/204 (46%), Gaps = 13/204 (6%)
Frame = +1
Query: 73 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEV-RELQKKLAQVEE------ 231
A+ ++Q E +++ + + R A + EK+ ++ REL++ ++EE
Sbjct: 343 ALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATS 402
Query: 232 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQ 396
+ +NK + + K + E+ EA AAL +K V ++ E ++ + +
Sbjct: 403 VQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 462
Query: 397 QKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 573
++ E + D+ + M ++++ +A E+ L +Q+ E R AE+ ++++ +
Sbjct: 463 KEKSEFKLELDDVTSNMEQIIKAKANL-EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQQ 521
Query: 574 AFVEDELEVAEDRVKSGDAKISEL 645
A ++ E ++ +A IS+L
Sbjct: 522 AKLQTENGELSRQLDEKEALISQL 545
>AK093285-1|BAC04121.1| 797|Homo sapiens protein ( Homo sapiens cDNA
FLJ35966 fis, clone TESTI2012628, moderately similar to
Mus musculus STAP mRNA for sperm tail associated protein.
).
Length = 797
Score = 55.2 bits (127), Expect = 2e-07
Identities = 49/212 (23%), Positives = 99/212 (46%), Gaps = 8/212 (3%)
Frame = +1
Query: 79 KKKMQAMKLE---KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLA-----QVEED 234
K++ A +LE K+ DK+ E +A A ++ K + E + Q++LA Q +E+
Sbjct: 433 KQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQERLAAQQAAQCKEE 492
Query: 235 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 414
L LE + L++ Q T T+ AL+RK ++DL ++ E+ +
Sbjct: 493 AALAGCHLEDTQRKLQKHYLQTTITKEAYDALSRKSAACQDDLTQALEKLNHVTSETKSL 552
Query: 415 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 594
QQS + LE EERM +L +L++ R ++++ + +KL + ++
Sbjct: 553 QQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRGFHQESELEVHAFDKKLEEMSCQV 612
Query: 595 EVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
+ + ++ ++ EE+L+ + +L+
Sbjct: 613 LQWQKQHQNDLKMLAAKEEQLREFQEEMAALK 644
Score = 47.2 bits (107), Expect = 6e-05
Identities = 36/210 (17%), Positives = 95/210 (45%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
IKK ++ ++ +KD+ + + +D + E V+E+ R + K + ++E DL
Sbjct: 304 IKKILKHLQEQKDSQCLHVEEYQNLVKDLRVELEAVSEQKRNIMKDMMKLELDL---HGL 360
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
E+ + +E K+K +T + + L + + ++ K ++ + L E ++ +
Sbjct: 361 REETSAHIERKDKDITILQCRLQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKLTQV 420
Query: 436 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 615
E ++ + +L +KEA+ + + + + ++ +++ LE A+ +
Sbjct: 421 QNSLLKKEKELEKQQCMATELEMTVKEAK-QDKSKEAECKALQAEVQKLKNSLEEAKQQE 479
Query: 616 KSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+ + ++ +EE + G L+ + +K
Sbjct: 480 RLAAQQAAQCKEEAALAGCHLEDTQRKLQK 509
Score = 39.1 bits (87), Expect = 0.016
Identities = 30/202 (14%), Positives = 83/202 (41%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+ K A A++ ++Q +K + A + QQA A + + Q+KL +
Sbjct: 452 KSKEAECKALQAEVQKLKNSLEEAKQQERLAAQQAAQCKEEAALAGCHLEDTQRKLQKHY 511
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
+ K + ++ + LT ++ + + + +++ L +++E+ +++++
Sbjct: 512 LQTTITKEAYDALSRKSAACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEII 571
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
++ + N + L Q+ E + +L+E + + LA E+
Sbjct: 572 AYEERMKKLNTELRKLRGFHQESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEE 631
Query: 589 ELEVAEDRVKSGDAKISELEEE 654
+L ++ + + + E ++E
Sbjct: 632 QLREFQEEMAALKENLLEDDKE 653
Score = 33.5 bits (73), Expect = 0.78
Identities = 38/165 (23%), Positives = 75/165 (45%), Gaps = 10/165 (6%)
Frame = +1
Query: 187 EEVRELQKKLAQV------EEDLILN-KNKLEQANKDLEEKEKQLTATEAEVA---ALNR 336
+E +E QK+L++V ++DLI +NKL +N + E+EK L +A+ A A +R
Sbjct: 233 QEHQEAQKRLSEVWQKVSQQDDLIQELRNKLACSNALVLEREKALIKLQADFASCTATHR 292
Query: 337 KVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKE 516
E+ E ++ Q++ +E + K L + E Q N +K+
Sbjct: 293 YPPSSSEECEDIKKILKHLQEQKDSQCLHVEEYQNLVKDLRVELEAVSE---QKRNIMKD 349
Query: 517 ARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE 651
L D G +E S + + ++ + + R++ + +E ++
Sbjct: 350 MMKLELDLHGLREETSAHIERKDKDITILQCRLQELQLEFTETQK 394
>AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 55.2 bits (127), Expect = 2e-07
Identities = 57/230 (24%), Positives = 114/230 (49%), Gaps = 14/230 (6%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 243
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 1526 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 1582
Query: 244 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 411
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 1583 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1638
Query: 412 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 564
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 1639 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1698
Query: 565 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
RKLA E EL +RV+ ++ + L + K + L L+ E+A Q
Sbjct: 1699 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQ 1746
Score = 54.8 bits (126), Expect = 3e-07
Identities = 55/227 (24%), Positives = 105/227 (46%), Gaps = 15/227 (6%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 246
++K+ KLE D+ + + + + +++ E + K + + DL
Sbjct: 1217 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 1276
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTAQQKLLEA 414
+ KL+ N +L +QL EA ++ L R QQ+ EDL++ E A+ L A
Sbjct: 1277 RAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKAKNALAHA 1332
Query: 415 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRK 570
QSA + C +L + +++ E +L L +A +A+ DA +++E+
Sbjct: 1333 LQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 1389
Query: 571 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
+ L+ AE+ V++ +AK S LE+ + N ++ L V E++N
Sbjct: 1390 KKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/203 (21%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 502 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISEL 645
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Query: 646 EEELKVVGNSLKSLEVSEEKANQ 714
+ E + +L+ + E N+
Sbjct: 1602 DAETRSRNEALRVKKKMEGDLNE 1624
Score = 53.6 bits (123), Expect = 7e-07
Identities = 54/221 (24%), Positives = 100/221 (45%), Gaps = 7/221 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+++ +A+ +Q+ + + D ++ + + + K N EV + + K E
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY---E 1376
Query: 229 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 387
D I +LE+A K L +E E+ + A A+ ++L + +++ EDL ERS
Sbjct: 1377 TDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
A L + Q++ D K+L Q+ EE +L + KEAR L+ + +
Sbjct: 1437 AAAAALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 1490
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
L + LE + K+ +IS+L E+L G ++ LE
Sbjct: 1491 SL----EHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 1527
Score = 50.8 bits (116), Expect = 5e-06
Identities = 49/230 (21%), Positives = 102/230 (44%), Gaps = 15/230 (6%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 258
K K +LE + M+ T ++ R ++ ++ +L+ LA+VE++ +NK+
Sbjct: 918 KVKEMNERLEDEEEMNAELTAKK--RKLEDECSELKRDIDDLELTLAKVEKEKHATENKV 975
Query: 259 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 438
+ +++ ++ + E AL QQ +DL+ E++ T + ++ +Q D+
Sbjct: 976 KNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLE 1035
Query: 439 RMCKVLENRAQQDEERMDQ-LTNQLKEARLLAEDADGKSDEVSRKL-----------AFV 582
+ E + + D ER + L LK + D + ++ +L A +
Sbjct: 1036 GSLEQ-EKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARI 1094
Query: 583 EDELEVA---EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
EDE + + ++K A+I ELEEEL+ + +E ++ +E
Sbjct: 1095 EDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELE 1144
Score = 50.0 bits (114), Expect = 8e-06
Identities = 48/215 (22%), Positives = 105/215 (48%), Gaps = 12/215 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQ----AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 216
++ A + A K+K++ +K + D+ E++ + + + EE+ L + +
Sbjct: 930 EEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 989
Query: 217 AQVEEDLILNKNKLEQANKDLE-EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 393
A++ ++ + +QA DL+ E++K T T+A+V K++Q +DLE S E+
Sbjct: 990 AKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKV-----KLEQQVDDLEGSLEQEKKV 1044
Query: 394 QQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 561
+ L A++ + + ++ + LEN QQ +ER+ + +L ED ++
Sbjct: 1045 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 1104
Query: 562 SRKLAFVEDELEVAEDRV---KSGDAKISELEEEL 657
+KL ++ +E E+ + ++ AK+ +L +L
Sbjct: 1105 QKKLKELQARIEELEEELEAERTARAKVEKLRSDL 1139
Score = 49.2 bits (112), Expect = 1e-05
Identities = 49/233 (21%), Positives = 101/233 (43%), Gaps = 13/233 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEV 195
++K ++ K +Q ++ E+DN D + C+Q + ++ N R E E
Sbjct: 874 EEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 933
Query: 196 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 375
EL K ++E++ K ++ L + EK+ ATE +V L ++ ++E + K
Sbjct: 934 AELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 993
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
+ Q+ +A L + E+++D L L++ + + D +
Sbjct: 994 KEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL----E 1049
Query: 556 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSL--EVSEEKA 708
RKL E +L++ ++ + + +L+E LK L +L + +E+A
Sbjct: 1050 RAKRKL---EGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQA 1099
Score = 46.4 bits (105), Expect = 1e-04
Identities = 33/153 (21%), Positives = 72/153 (47%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
QQA D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 1004 QQALD-DLQAEE--DKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1060
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
+ +E D ++ +ER +L ++ + L+ + ++ + R+++L
Sbjct: 1061 LTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEE 1120
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 603
+L+ R + ++SR+L + + LE A
Sbjct: 1121 ELEAERTARAKVEKLRSDLSRELEEISERLEEA 1153
Score = 44.4 bits (100), Expect = 4e-04
Identities = 36/149 (24%), Positives = 72/149 (48%), Gaps = 7/149 (4%)
Frame = +1
Query: 283 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 462
E+EK++ A++ + +++E LEKSE R ++K++ Q ++ + ++
Sbjct: 844 EREKEM-------ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 896
Query: 463 RAQQDEERMDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 621
EER DQL ++KE ED + + E++ K +EDE + +
Sbjct: 897 NLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDD 956
Query: 622 GDAKISELEEELKVVGNSLKSLEVSEEKA 708
+ ++++E+E N +K+L +EE A
Sbjct: 957 LELTLAKVEKEKHATENKVKNL--TEEMA 983
Score = 36.7 bits (81), Expect = 0.084
Identities = 41/204 (20%), Positives = 95/204 (46%), Gaps = 13/204 (6%)
Frame = +1
Query: 73 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEV-RELQKKLAQVEE------ 231
A+ ++Q E +++ + + R A + EK+ ++ REL++ ++EE
Sbjct: 1099 ALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATS 1158
Query: 232 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQ 396
+ +NK + + K + E+ EA AAL +K V ++ E ++ + +
Sbjct: 1159 CQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 1218
Query: 397 QKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 573
++ E + D+ + M ++++ +A E+ L +Q+ E R AE+ ++++ +
Sbjct: 1219 KEKSEFKLELDDVTSNMEQIIKAKANL-EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277
Query: 574 AFVEDELEVAEDRVKSGDAKISEL 645
A ++ E ++ +A IS+L
Sbjct: 1278 AKLQTENGELSRQLDEKEALISQL 1301
>AF034799-1|AAC26100.1| 1257|Homo sapiens liprin-alpha2 protein.
Length = 1257
Score = 55.2 bits (127), Expect = 2e-07
Identities = 44/181 (24%), Positives = 82/181 (45%), Gaps = 4/181 (2%)
Frame = +1
Query: 187 EEVRELQK-KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 363
+E+ E Q ++AQ++E L +++ + ++ E K L TE R +++
Sbjct: 274 QELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQK 333
Query: 364 EKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDE---ERMDQLTNQLKEARLLAE 534
E EER T +++ L AQ+ + + M LEN E +M++ QL+E LAE
Sbjct: 334 EDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAE 393
Query: 535 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
+ ++ + L VE EL + + +EE ++ + L+ ++A Q
Sbjct: 394 EKLQQTMRKAETLPEVEAELAQRIAALTKAEETHGNIEERMRHLEGQLEEKNQELQRARQ 453
Query: 715 R 717
R
Sbjct: 454 R 454
Score = 44.4 bits (100), Expect = 4e-04
Identities = 41/165 (24%), Positives = 81/165 (49%), Gaps = 2/165 (1%)
Frame = +1
Query: 103 LEKDNAMDKADTCEQQARDANLRAEKVNEE--VRELQKKLAQVEEDLILNKNKLEQANKD 276
LEK + ++ + L E N+E +R++++K Q++E L L + KL+Q +
Sbjct: 343 LEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEEKLQQTMR- 401
Query: 277 LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 456
K + L EAE+A Q+I L K+EE G ++++ + +E N+ +
Sbjct: 402 ---KAETLPEVEAELA------QRIAA-LTKAEETHGNIEERMRHLEGQLEEKNQELQRA 451
Query: 457 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 591
R + +EE +L++ + RLL E + + ++A +E++
Sbjct: 452 RQREKMNEEHNKRLSDTVD--RLLTESNERLQLHLKERMAALEEK 494
>AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypeptide 7,
cardiac muscle, beta variant protein.
Length = 1574
Score = 55.2 bits (127), Expect = 2e-07
Identities = 57/230 (24%), Positives = 114/230 (49%), Gaps = 14/230 (6%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 243
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 1165 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 1221
Query: 244 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 411
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 1222 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1277
Query: 412 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 564
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 1278 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1337
Query: 565 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
RKLA E EL +RV+ ++ + L + K + L L+ E+A Q
Sbjct: 1338 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQ 1385
Score = 54.8 bits (126), Expect = 3e-07
Identities = 55/227 (24%), Positives = 105/227 (46%), Gaps = 15/227 (6%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 246
++K+ KLE D+ + + + + +++ E + K + + DL
Sbjct: 856 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 915
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTAQQKLLEA 414
+ KL+ N +L +QL EA ++ L R QQ+ EDL++ E A+ L A
Sbjct: 916 RAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKAKNALAHA 971
Query: 415 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRK 570
QSA + C +L + +++ E +L L +A +A+ DA +++E+
Sbjct: 972 LQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 1028
Query: 571 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
+ L+ AE+ V++ +AK S LE+ + N ++ L V E++N
Sbjct: 1029 KKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1075
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/203 (21%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1061 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1120
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 1121 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1180
Query: 502 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISEL 645
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 1181 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1240
Query: 646 EEELKVVGNSLKSLEVSEEKANQ 714
+ E + +L+ + E N+
Sbjct: 1241 DAETRSRNEALRVKKKMEGDLNE 1263
Score = 53.6 bits (123), Expect = 7e-07
Identities = 54/221 (24%), Positives = 100/221 (45%), Gaps = 7/221 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+++ +A+ +Q+ + + D ++ + + + K N EV + + K E
Sbjct: 959 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY---E 1015
Query: 229 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 387
D I +LE+A K L +E E+ + A A+ ++L + +++ EDL ERS
Sbjct: 1016 TDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1075
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
A L + Q++ D K+L Q+ EE +L + KEAR L+ + +
Sbjct: 1076 AAAAALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 1129
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
L + LE + K+ +IS+L E+L G ++ LE
Sbjct: 1130 SL----EHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 1166
Score = 50.8 bits (116), Expect = 5e-06
Identities = 49/230 (21%), Positives = 102/230 (44%), Gaps = 15/230 (6%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 258
K K +LE + M+ T ++ R ++ ++ +L+ LA+VE++ +NK+
Sbjct: 557 KVKEMNERLEDEEEMNAELTAKK--RKLEDECSELKRDIDDLELTLAKVEKEKHATENKV 614
Query: 259 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 438
+ +++ ++ + E AL QQ +DL+ E++ T + ++ +Q D+
Sbjct: 615 KNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLE 674
Query: 439 RMCKVLENRAQQDEERMDQ-LTNQLKEARLLAEDADGKSDEVSRKL-----------AFV 582
+ E + + D ER + L LK + D + ++ +L A +
Sbjct: 675 GSLEQ-EKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARI 733
Query: 583 EDELEVA---EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
EDE + + ++K A+I ELEEEL+ + +E ++ +E
Sbjct: 734 EDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELE 783
Score = 50.0 bits (114), Expect = 8e-06
Identities = 48/215 (22%), Positives = 105/215 (48%), Gaps = 12/215 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQ----AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 216
++ A + A K+K++ +K + D+ E++ + + + EE+ L + +
Sbjct: 569 EEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 628
Query: 217 AQVEEDLILNKNKLEQANKDLE-EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 393
A++ ++ + +QA DL+ E++K T T+A+V K++Q +DLE S E+
Sbjct: 629 AKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKV-----KLEQQVDDLEGSLEQEKKV 683
Query: 394 QQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 561
+ L A++ + + ++ + LEN QQ +ER+ + +L ED ++
Sbjct: 684 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 743
Query: 562 SRKLAFVEDELEVAEDRV---KSGDAKISELEEEL 657
+KL ++ +E E+ + ++ AK+ +L +L
Sbjct: 744 QKKLKELQARIEELEEELEAERTARAKVEKLRSDL 778
Score = 49.2 bits (112), Expect = 1e-05
Identities = 49/233 (21%), Positives = 101/233 (43%), Gaps = 13/233 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEV 195
++K ++ K +Q ++ E+DN D + C+Q + ++ N R E E
Sbjct: 513 EEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 572
Query: 196 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 375
EL K ++E++ K ++ L + EK+ ATE +V L ++ ++E + K
Sbjct: 573 AELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 632
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
+ Q+ +A L + E+++D L L++ + + D +
Sbjct: 633 KEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL----E 688
Query: 556 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSL--EVSEEKA 708
RKL E +L++ ++ + + +L+E LK L +L + +E+A
Sbjct: 689 RAKRKL---EGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQA 738
Score = 46.4 bits (105), Expect = 1e-04
Identities = 33/153 (21%), Positives = 72/153 (47%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
QQA D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 643 QQALD-DLQAEE--DKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 699
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
+ +E D ++ +ER +L ++ + L+ + ++ + R+++L
Sbjct: 700 LTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEE 759
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 603
+L+ R + ++SR+L + + LE A
Sbjct: 760 ELEAERTARAKVEKLRSDLSRELEEISERLEEA 792
Score = 44.4 bits (100), Expect = 4e-04
Identities = 36/149 (24%), Positives = 72/149 (48%), Gaps = 7/149 (4%)
Frame = +1
Query: 283 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 462
E+EK++ A++ + +++E LEKSE R ++K++ Q ++ + ++
Sbjct: 483 EREKEM-------ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 535
Query: 463 RAQQDEERMDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 621
EER DQL ++KE ED + + E++ K +EDE + +
Sbjct: 536 NLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDD 595
Query: 622 GDAKISELEEELKVVGNSLKSLEVSEEKA 708
+ ++++E+E N +K+L +EE A
Sbjct: 596 LELTLAKVEKEKHATENKVKNL--TEEMA 622
Score = 36.7 bits (81), Expect = 0.084
Identities = 41/204 (20%), Positives = 95/204 (46%), Gaps = 13/204 (6%)
Frame = +1
Query: 73 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEV-RELQKKLAQVEE------ 231
A+ ++Q E +++ + + R A + EK+ ++ REL++ ++EE
Sbjct: 738 ALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATS 797
Query: 232 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQ 396
+ +NK + + K + E+ EA AAL +K V ++ E ++ + +
Sbjct: 798 VQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 857
Query: 397 QKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 573
++ E + D+ + M ++++ +A E+ L +Q+ E R AE+ ++++ +
Sbjct: 858 KEKSEFKLELDDVTSNMEQIIKAKANL-EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 916
Query: 574 AFVEDELEVAEDRVKSGDAKISEL 645
A ++ E ++ +A IS+L
Sbjct: 917 AKLQTENGELSRQLDEKEALISQL 940
>X52889-1|CAA37068.1| 1934|Homo sapiens cardiac beta myosin heavy
chain protein.
Length = 1934
Score = 54.8 bits (126), Expect = 3e-07
Identities = 55/227 (24%), Positives = 105/227 (46%), Gaps = 15/227 (6%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 246
++K+ KLE D+ + + + + +++ E + K + + DL
Sbjct: 1217 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 1276
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTAQQKLLEA 414
+ KL+ N +L +QL EA ++ L R QQ+ EDL++ E A+ L A
Sbjct: 1277 RAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKAKNALAHA 1332
Query: 415 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRK 570
QSA + C +L + +++ E +L L +A +A+ DA +++E+
Sbjct: 1333 LQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 1389
Query: 571 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
+ L+ AE+ V++ +AK S LE+ + N ++ L V E++N
Sbjct: 1390 KKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/203 (21%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 502 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISEL 645
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Query: 646 EEELKVVGNSLKSLEVSEEKANQ 714
+ E + +L+ + E N+
Sbjct: 1602 DAETRSRNEALRVKKKMEGDLNE 1624
Score = 53.6 bits (123), Expect = 7e-07
Identities = 54/221 (24%), Positives = 100/221 (45%), Gaps = 7/221 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+++ +A+ +Q+ + + D ++ + + + K N EV + + K E
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY---E 1376
Query: 229 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 387
D I +LE+A K L +E E+ + A A+ ++L + +++ EDL ERS
Sbjct: 1377 TDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
A L + Q++ D K+L Q+ EE +L + KEAR L+ + +
Sbjct: 1437 AAAAALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 1490
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
L + LE + K+ +IS+L E+L G ++ LE
Sbjct: 1491 SL----EHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 1527
Score = 52.4 bits (120), Expect = 2e-06
Identities = 51/211 (24%), Positives = 101/211 (47%), Gaps = 18/211 (8%)
Frame = +1
Query: 79 KKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI-LNK- 249
+++M A + +K N D+ ++ D L KV +E + K+ + E++ L++
Sbjct: 929 EEEMNAELTAKKRNVEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEI 988
Query: 250 -NKLEQANKDLEEKEKQ----LTATEAEVAALNR---KVQQIEEDLEKSEERSGTAQQKL 405
KL + K L+E +Q L A E +V L + K++Q +DLE S E+ + L
Sbjct: 989 IAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL 1048
Query: 406 LEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 573
A++ + + ++ + LEN QQ +ER+ + +L ED ++ +KL
Sbjct: 1049 ERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKL 1108
Query: 574 AFVEDELEVAEDRV---KSGDAKISELEEEL 657
++ +E E+ + ++ AK+ +L +L
Sbjct: 1109 KELQARIEELEEELEAERTARAKVEKLRSDL 1139
Score = 52.4 bits (120), Expect = 2e-06
Identities = 57/239 (23%), Positives = 116/239 (48%), Gaps = 25/239 (10%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 243
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 1526 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 1582
Query: 244 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 411
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 1583 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1638
Query: 412 AQQSADENNRMCK----VLEN--RAQQD-------EERMDQLTNQLKEARLLAED----- 537
AQ+ + K L++ RA D ER + L +L+E R + E
Sbjct: 1639 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLQAELEELRAVVEQTERSR 1698
Query: 538 --ADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 708
AD + E S ++ + + ++ K DA +S+L+ E++ ++ E +KA
Sbjct: 1699 KLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA 1757
Score = 52.0 bits (119), Expect = 2e-06
Identities = 49/230 (21%), Positives = 103/230 (44%), Gaps = 15/230 (6%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 258
K K +LE + M+ T ++ R+ ++ ++ +L+ LA+VE++ +NK+
Sbjct: 918 KVKEMNERLEDEEEMNAELTAKK--RNVEDECSELKRDIDDLELTLAKVEKEKHATENKV 975
Query: 259 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 438
+ +++ ++ + E AL QQ +DL+ E++ T + ++ +Q D+
Sbjct: 976 KNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLE 1035
Query: 439 RMCKVLENRAQQDEERMDQ-LTNQLKEARLLAEDADGKSDEVSRKL-----------AFV 582
+ E + + D ER + L LK + D + ++ +L A +
Sbjct: 1036 GSLEQ-EKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARI 1094
Query: 583 EDELEVA---EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
EDE + + ++K A+I ELEEEL+ + +E ++ +E
Sbjct: 1095 EDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELE 1144
Score = 50.0 bits (114), Expect = 8e-06
Identities = 50/233 (21%), Positives = 100/233 (42%), Gaps = 13/233 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEV 195
++K ++ K +Q ++ E+DN D + C+Q + ++ N R E E
Sbjct: 874 EEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 933
Query: 196 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 375
EL K VE++ K ++ L + EK+ ATE +V L ++ ++E + K
Sbjct: 934 AELTAKKRNVEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 993
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
+ Q+ +A L + E+++D L L++ + + D +
Sbjct: 994 KEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL----E 1049
Query: 556 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSL--EVSEEKA 708
RKL E +L++ ++ + + +L+E LK L +L + +E+A
Sbjct: 1050 RAKRKL---EGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQA 1099
Score = 46.8 bits (106), Expect = 8e-05
Identities = 39/149 (26%), Positives = 71/149 (47%), Gaps = 7/149 (4%)
Frame = +1
Query: 283 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 462
E+EK++ + + E AL +E LEKSE R ++K++ Q ++ + ++
Sbjct: 844 EREKEMASMKEEFTAL-------KEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 896
Query: 463 RAQQDEERMDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 621
EER DQL ++KE ED + + E++ K VEDE + +
Sbjct: 897 NLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRNVEDECSELKRDIDD 956
Query: 622 GDAKISELEEELKVVGNSLKSLEVSEEKA 708
+ ++++E+E N +K+L +EE A
Sbjct: 957 LELTLAKVEKEKHATENKVKNL--TEEMA 983
Score = 46.4 bits (105), Expect = 1e-04
Identities = 33/153 (21%), Positives = 72/153 (47%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
QQA D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 1004 QQALD-DLQAEE--DKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1060
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
+ +E D ++ +ER +L ++ + L+ + ++ + R+++L
Sbjct: 1061 LTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEE 1120
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 603
+L+ R + ++SR+L + + LE A
Sbjct: 1121 ELEAERTARAKVEKLRSDLSRELEEISERLEEA 1153
Score = 36.7 bits (81), Expect = 0.084
Identities = 41/204 (20%), Positives = 95/204 (46%), Gaps = 13/204 (6%)
Frame = +1
Query: 73 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEV-RELQKKLAQVEE------ 231
A+ ++Q E +++ + + R A + EK+ ++ REL++ ++EE
Sbjct: 1099 ALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATS 1158
Query: 232 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQ 396
+ +NK + + K + E+ EA AAL +K V ++ E ++ + +
Sbjct: 1159 CQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 1218
Query: 397 QKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 573
++ E + D+ + M ++++ +A E+ L +Q+ E R AE+ ++++ +
Sbjct: 1219 KEKSEFKLELDDVTSNMEQIIKAKANL-EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277
Query: 574 AFVEDELEVAEDRVKSGDAKISEL 645
A ++ E ++ +A IS+L
Sbjct: 1278 AKLQTENGELSRQLDEKEALISQL 1301
>X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain (1151
AA) protein.
Length = 1151
Score = 54.8 bits (126), Expect = 3e-07
Identities = 55/227 (24%), Positives = 105/227 (46%), Gaps = 15/227 (6%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 246
++K+ KLE D+ + + + + +++ E + K + + DL
Sbjct: 433 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 492
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTAQQKLLEA 414
+ KL+ N +L +QL EA ++ L R QQ+ EDL++ E A+ L A
Sbjct: 493 RAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKAKNALAHA 548
Query: 415 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRK 570
QSA + C +L + +++ E +L L +A +A+ DA +++E+
Sbjct: 549 LQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 605
Query: 571 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
+ L+ AE+ V++ +AK S LE+ + N ++ L V E++N
Sbjct: 606 KKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 652
Score = 54.8 bits (126), Expect = 3e-07
Identities = 56/230 (24%), Positives = 115/230 (50%), Gaps = 14/230 (6%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 243
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 742 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 798
Query: 244 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 411
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 799 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 854
Query: 412 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 564
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 855 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 914
Query: 565 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
RKLA ++EL +RV+ ++ + L + K + L L+ E+A Q
Sbjct: 915 RKLA--DEELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQ 962
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/203 (21%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 638 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 697
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 698 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 757
Query: 502 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISEL 645
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 758 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 817
Query: 646 EEELKVVGNSLKSLEVSEEKANQ 714
+ E + +L+ + E N+
Sbjct: 818 DAETRSRNEALRVKKKMEGDLNE 840
Score = 53.6 bits (123), Expect = 7e-07
Identities = 54/221 (24%), Positives = 100/221 (45%), Gaps = 7/221 (3%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+++ +A+ +Q+ + + D ++ + + + K N EV + + K E
Sbjct: 536 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY---E 592
Query: 229 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 387
D I +LE+A K L +E E+ + A A+ ++L + +++ EDL ERS
Sbjct: 593 TDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 652
Query: 388 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 567
A L + Q++ D K+L Q+ EE +L + KEAR L+ + +
Sbjct: 653 AAAAALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 706
Query: 568 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
L + LE + K+ +IS+L E+L G ++ LE
Sbjct: 707 SL----EHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 743
Score = 51.2 bits (117), Expect = 4e-06
Identities = 50/229 (21%), Positives = 104/229 (45%), Gaps = 14/229 (6%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 258
K K +LE + M+ T ++ R ++ ++ +L+ LA+VE++ +NK+
Sbjct: 134 KVKEMNERLEDEEEMNAELTAKK--RKLEDECSELKRDIDDLELTLAKVEKEKHATENKV 191
Query: 259 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD--- 429
+ +++ ++ + E AL QQ +DL+ E++ T + ++ +Q D
Sbjct: 192 KNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLE 251
Query: 430 ---ENNRMCKVLENRAQQDEERMDQLTNQL-----KEARLLAEDADGKSDEVSRKLAFVE 585
E + ++ RA++ E +LT + + + L E K E++ A +E
Sbjct: 252 GSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLEERLKKKDFELNALNARIE 311
Query: 586 DELEVA---EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
DE + + ++K A+I ELEEEL+ + +E ++ +E
Sbjct: 312 DEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELE 360
Score = 51.2 bits (117), Expect = 4e-06
Identities = 49/215 (22%), Positives = 105/215 (48%), Gaps = 12/215 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQ----AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 216
++ A + A K+K++ +K + D+ E++ + + + EE+ L + +
Sbjct: 146 EEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 205
Query: 217 AQVEEDLILNKNKLEQANKDLE-EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 393
A++ ++ + +QA DL+ E++K T T+A+V K++Q +DLE S E+
Sbjct: 206 AKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKV-----KLEQQVDDLEGSLEQEKKV 260
Query: 394 QQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 561
+ L A++ + + ++ + LEN QQ EER+ + +L ED ++
Sbjct: 261 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLEERLKKKDFELNALNARIEDEQALGSQL 320
Query: 562 SRKLAFVEDELEVAEDRV---KSGDAKISELEEEL 657
+KL ++ +E E+ + ++ AK+ +L +L
Sbjct: 321 QKKLKELQARIEELEEELEAERTARAKVEKLRSDL 355
Score = 50.4 bits (115), Expect = 6e-06
Identities = 50/233 (21%), Positives = 101/233 (43%), Gaps = 13/233 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEV 195
++K ++ K +Q ++ E+DN D + C+Q + ++ N R E E
Sbjct: 90 EEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 149
Query: 196 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 375
EL K ++E++ K ++ L + EK+ ATE +V L ++ ++E + K
Sbjct: 150 AELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 209
Query: 376 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 555
+ Q+ +A L + E+++D L L++ + + D +
Sbjct: 210 KEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL----E 265
Query: 556 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSL--EVSEEKA 708
RKL E +L++ ++ + + +LEE LK L +L + +E+A
Sbjct: 266 RAKRKL---EGDLKLTQESIMDLENDKQQLEERLKKKDFELNALNARIEDEQA 315
Score = 47.6 bits (108), Expect = 4e-05
Identities = 34/153 (22%), Positives = 72/153 (47%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
QQA D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 220 QQALD-DLQAEE--DKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 276
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
+ +E D ++ EER +L ++ + L+ + ++ + R+++L
Sbjct: 277 LTQESIMDLENDKQQLEERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEE 336
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 603
+L+ R + ++SR+L + + LE A
Sbjct: 337 ELEAERTARAKVEKLRSDLSRELEEISERLEEA 369
Score = 44.4 bits (100), Expect = 4e-04
Identities = 36/149 (24%), Positives = 72/149 (48%), Gaps = 7/149 (4%)
Frame = +1
Query: 283 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 462
E+EK++ A++ + +++E LEKSE R ++K++ Q ++ + ++
Sbjct: 60 EREKEM-------ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 112
Query: 463 RAQQDEERMDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 621
EER DQL ++KE ED + + E++ K +EDE + +
Sbjct: 113 NLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDD 172
Query: 622 GDAKISELEEELKVVGNSLKSLEVSEEKA 708
+ ++++E+E N +K+L +EE A
Sbjct: 173 LELTLAKVEKEKHATENKVKNL--TEEMA 199
Score = 36.7 bits (81), Expect = 0.084
Identities = 41/204 (20%), Positives = 95/204 (46%), Gaps = 13/204 (6%)
Frame = +1
Query: 73 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEV-RELQKKLAQVEE------ 231
A+ ++Q E +++ + + R A + EK+ ++ REL++ ++EE
Sbjct: 315 ALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATS 374
Query: 232 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQ 396
+ +NK + + K + E+ EA AAL +K V ++ E ++ + +
Sbjct: 375 VQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 434
Query: 397 QKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 573
++ E + D+ + M ++++ +A E+ L +Q+ E R AE+ ++++ +
Sbjct: 435 KEKSEFKLELDDVTSNMEQIIKAKANL-EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 493
Query: 574 AFVEDELEVAEDRVKSGDAKISEL 645
A ++ E ++ +A IS+L
Sbjct: 494 AKLQTENGELSRQLDEKEALISQL 517
>BC129803-1|AAI29804.1| 638|Homo sapiens MYH14 protein protein.
Length = 638
Score = 54.4 bits (125), Expect = 4e-07
Identities = 51/224 (22%), Positives = 98/224 (43%), Gaps = 8/224 (3%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
+++++ A + A D + + NL + EE R+L+ +L Q+EE+L ++
Sbjct: 352 LQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSN 411
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
E N + Q+ + E++A + E ++ E + + +L E A
Sbjct: 412 SELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARAR 471
Query: 436 NRMC-KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV------SRKLAF-VEDE 591
++M LE++ Q EE+++Q T + + L A+ + EV R++A + D+
Sbjct: 472 HKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQ 531
Query: 592 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
LE RVK ++ E EEE + L+ E + E
Sbjct: 532 LEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAE 575
Score = 52.0 bits (119), Expect = 2e-06
Identities = 42/185 (22%), Positives = 85/185 (45%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
E+ R A AE + + + E + + ++E + +L+ A DLE+ ++QL +T
Sbjct: 51 EEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQ-QRQLVST---- 105
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
L +K ++ ++ L + + A ++ A+ E L ++++E ++L
Sbjct: 106 --LEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELE 163
Query: 502 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 681
Q + R E D+V + + +E VAE A+++ELE+EL ++
Sbjct: 164 RQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKL 223
Query: 682 SLEVS 696
LEV+
Sbjct: 224 RLEVT 228
Score = 42.7 bits (96), Expect = 0.001
Identities = 33/174 (18%), Positives = 75/174 (43%)
Frame = +1
Query: 88 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 267
++A + + A +A+ Q+ + +++ R LQ++L DL + +
Sbjct: 47 LEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTL 106
Query: 268 NKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMC 447
K + ++ L +A V + ++ E + + E R+ + + L E Q++ +E R
Sbjct: 107 EKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQN 166
Query: 448 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 609
+ L + D + + E A+ ++++ ++ +EDEL AED
Sbjct: 167 RALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAED 220
>BC103824-1|AAI03825.1| 546|Homo sapiens taxilin alpha protein.
Length = 546
Score = 54.4 bits (125), Expect = 4e-07
Identities = 47/213 (22%), Positives = 102/213 (47%), Gaps = 7/213 (3%)
Frame = +1
Query: 88 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 267
+Q + E++ + + D L+ E+ NE +L+++ ++ E L K +EQ
Sbjct: 260 VQRAREEEEKRKEVTSHFQVTLNDIQLQMEQHNERNSKLRQENMELAERL---KKLIEQY 316
Query: 268 NKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMC 447
E +K + + ++ K+QQ +E L+++EER + LL + A E+ RMC
Sbjct: 317 ELREEHIDKVFKHKDLQQQLVDAKLQQAQEMLKEAEERHQREKDFLL---KEAVESQRMC 373
Query: 448 KVL---ENRAQQD----EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
+++ E +Q E+ ++ N L ++ + + +++++K+ +E E +
Sbjct: 374 ELMKQQETHLKQQLALYTEKFEEFQNTLSKSSEVFTTFKQEMEKMTKKIKKLEKETTMYR 433
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
R +S + + E+ EE V L+ L+V ++
Sbjct: 434 SRWESSNKALLEMAEEKTVRDKELEGLQVKIQR 466
Score = 38.3 bits (85), Expect = 0.028
Identities = 15/57 (26%), Positives = 37/57 (64%)
Frame = +1
Query: 187 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE 357
+E+ ++ KK+ ++E++ + +++ E +NK L E ++ T + E+ L K+Q++E+
Sbjct: 413 QEMEKMTKKIKKLEKETTMYRSRWESSNKALLEMAEEKTVRDKELEGLQVKIQRLEK 469
>BC103823-1|AAI03824.1| 546|Homo sapiens taxilin alpha protein.
Length = 546
Score = 54.4 bits (125), Expect = 4e-07
Identities = 47/213 (22%), Positives = 102/213 (47%), Gaps = 7/213 (3%)
Frame = +1
Query: 88 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 267
+Q + E++ + + D L+ E+ NE +L+++ ++ E L K +EQ
Sbjct: 260 VQRAREEEEKRKEVTSHFQVTLNDIQLQMEQHNERNSKLRQENMELAERL---KKLIEQY 316
Query: 268 NKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMC 447
E +K + + ++ K+QQ +E L+++EER + LL + A E+ RMC
Sbjct: 317 ELREEHIDKVFKHKDLQQQLVDAKLQQAQEMLKEAEERHQREKDFLL---KEAVESQRMC 373
Query: 448 KVL---ENRAQQD----EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
+++ E +Q E+ ++ N L ++ + + +++++K+ +E E +
Sbjct: 374 ELMKQQETHLKQQLALYTEKFEEFQNTLSKSSEVFTTFKQEMEKMTKKIKKLEKETTMYR 433
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
R +S + + E+ EE V L+ L+V ++
Sbjct: 434 SRWESSNKALLEMAEEKTVRDKELEGLQVKIQR 466
Score = 38.3 bits (85), Expect = 0.028
Identities = 15/57 (26%), Positives = 37/57 (64%)
Frame = +1
Query: 187 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE 357
+E+ ++ KK+ ++E++ + +++ E +NK L E ++ T + E+ L K+Q++E+
Sbjct: 413 QEMEKMTKKIKKLEKETTMYRSRWESSNKALLEMAEEKTVRDKELEGLQVKIQRLEK 469
>BC080578-1|AAH80578.1| 546|Homo sapiens taxilin alpha protein.
Length = 546
Score = 54.4 bits (125), Expect = 4e-07
Identities = 47/213 (22%), Positives = 102/213 (47%), Gaps = 7/213 (3%)
Frame = +1
Query: 88 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 267
+Q + E++ + + D L+ E+ NE +L+++ ++ E L K +EQ
Sbjct: 260 VQRAREEEEKRKEVTSHFQVTLNDIQLQMEQHNERNSKLRQENMELAERL---KKLIEQY 316
Query: 268 NKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMC 447
E +K + + ++ K+QQ +E L+++EER + LL + A E+ RMC
Sbjct: 317 ELREEHIDKVFKHKDLQQQLVDAKLQQAQEMLKEAEERHQREKDFLL---KEAVESQRMC 373
Query: 448 KVL---ENRAQQD----EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
+++ E +Q E+ ++ N L ++ + + +++++K+ +E E +
Sbjct: 374 ELMKQQETHLKQQLALYTEKFEEFQNTLSKSSEVFTTFKQEMEKMTKKIKKLEKETTMYR 433
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
R +S + + E+ EE V L+ L+V ++
Sbjct: 434 SRWESSNKALLEMAEEKTVRDKELEGLQVKIQR 466
Score = 38.3 bits (85), Expect = 0.028
Identities = 15/57 (26%), Positives = 37/57 (64%)
Frame = +1
Query: 187 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE 357
+E+ ++ KK+ ++E++ + +++ E +NK L E ++ T + E+ L K+Q++E+
Sbjct: 413 QEMEKMTKKIKKLEKETTMYRSRWESSNKALLEMAEEKTVRDKELEGLQVKIQRLEK 469
>BC000676-1|AAH00676.2| 483|Homo sapiens MYH14 protein protein.
Length = 483
Score = 54.4 bits (125), Expect = 4e-07
Identities = 51/224 (22%), Positives = 98/224 (43%), Gaps = 8/224 (3%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
+++++ A + A D + + NL + EE R+L+ +L Q+EE+L ++
Sbjct: 197 LQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSN 256
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
E N + Q+ + E++A + E ++ E + + +L E A
Sbjct: 257 SELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARAR 316
Query: 436 NRMC-KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV------SRKLAF-VEDE 591
++M LE++ Q EE+++Q T + + L A+ + EV R++A + D+
Sbjct: 317 HKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQ 376
Query: 592 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
LE RVK ++ E EEE + L+ E + E
Sbjct: 377 LEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAE 420
Score = 31.1 bits (67), Expect = 4.2
Identities = 22/78 (28%), Positives = 40/78 (51%)
Frame = +1
Query: 463 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE 642
+ Q+ + ++ ++ L EA L ++D GKS + +E VAE A+++E
Sbjct: 2 KLQRAQAELENVSGALNEALLSSKDDVGKS------VHELERACRVAEQAANDLRAQVTE 55
Query: 643 LEEELKVVGNSLKSLEVS 696
LE+EL ++ LEV+
Sbjct: 56 LEDELTAAEDAKLRLEVT 73
>AY359522-1|AAQ57128.1| 657|Homo sapiens hypothetical protein
DKFZp761A078 protein.
Length = 657
Score = 54.4 bits (125), Expect = 4e-07
Identities = 49/223 (21%), Positives = 106/223 (47%), Gaps = 8/223 (3%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAM-DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
KK ++ + + + + ++ E +D R K + +REL+ KL+ VEE+L K +
Sbjct: 236 KKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQE 295
Query: 256 L-----EQANKDLE--EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 414
+ E + D+E EKEK + + +VA L ++++ ++ + +++E T Q++ +
Sbjct: 296 VLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVL 355
Query: 415 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 594
+++ ++N L E + L+ +L +A + + G + KL
Sbjct: 356 EENGEKNQVQLGKL-------EATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVT 408
Query: 595 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
E + + K+ + ++EL+ VG SL+ E K +++E
Sbjct: 409 IQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLE 451
Score = 30.7 bits (66), Expect = 5.5
Identities = 25/96 (26%), Positives = 45/96 (46%), Gaps = 3/96 (3%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQ---KKLAQVEEDLI 240
+ IKK +K K QQ + + EK+ +E +ELQ + L E+++
Sbjct: 385 EIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVC 444
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQ 348
+ +LE K LEE ++ L E + LN+++ +
Sbjct: 445 KLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNE 480
>AY165122-1|AAO39147.1| 1995|Homo sapiens myosin heavy chain protein.
Length = 1995
Score = 54.4 bits (125), Expect = 4e-07
Identities = 51/224 (22%), Positives = 98/224 (43%), Gaps = 8/224 (3%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
+++++ A + A D + + NL + EE R+L+ +L Q+EE+L ++
Sbjct: 1709 LQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSN 1768
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
E N + Q+ + E++A + E ++ E + + +L E A
Sbjct: 1769 SELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARAR 1828
Query: 436 NRMC-KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV------SRKLAF-VEDE 591
++M LE++ Q EE+++Q T + + L A+ + EV R++A + D+
Sbjct: 1829 HKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQ 1888
Query: 592 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
LE RVK ++ E EEE + L+ E + E
Sbjct: 1889 LEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAE 1932
Score = 52.0 bits (119), Expect = 2e-06
Identities = 42/185 (22%), Positives = 85/185 (45%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
E+ R A AE + + + E + + ++E + +L+ A DLE+ ++QL +T
Sbjct: 1408 EEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQ-QRQLVST---- 1462
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
L +K ++ ++ L + + A ++ A+ E L ++++E ++L
Sbjct: 1463 --LEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELE 1520
Query: 502 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 681
Q + R E D+V + + +E VAE A+++ELE+EL ++
Sbjct: 1521 RQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKL 1580
Query: 682 SLEVS 696
LEV+
Sbjct: 1581 RLEVT 1585
Score = 50.4 bits (115), Expect = 6e-06
Identities = 39/173 (22%), Positives = 74/173 (42%), Gaps = 1/173 (0%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
E+Q RD E + E+ + +E + ++ + K LEE+ + A E+
Sbjct: 1155 EKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQEL 1214
Query: 322 AALN-RKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQL 498
+ + + ++ E LE++ G ++ L + E L+ Q+ E+R +L
Sbjct: 1215 RQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRL 1274
Query: 499 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 657
QL+E + A D + E + KL + ELE + ++K L +EL
Sbjct: 1275 ELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKEL 1327
Score = 42.7 bits (96), Expect = 0.001
Identities = 33/174 (18%), Positives = 75/174 (43%)
Frame = +1
Query: 88 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 267
++A + + A +A+ Q+ + +++ R LQ++L DL + +
Sbjct: 1404 LEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTL 1463
Query: 268 NKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMC 447
K + ++ L +A V + ++ E + + E R+ + + L E Q++ +E R
Sbjct: 1464 EKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQN 1523
Query: 448 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 609
+ L + D + + E A+ ++++ ++ +EDEL AED
Sbjct: 1524 RALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAED 1577
Score = 41.1 bits (92), Expect = 0.004
Identities = 44/213 (20%), Positives = 92/213 (43%), Gaps = 11/213 (5%)
Frame = +1
Query: 112 DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKE 291
D +A+ E+ R A E V+ + E + K ++ ++L + +L A + L+E+
Sbjct: 1287 DGERARAEAAEKLQR-AQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEET 1345
Query: 292 K-------QLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 450
+ ++ A EAE A L ++++ E++ TAQ +L E ++ +E +
Sbjct: 1346 RAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALE 1405
Query: 451 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDA 630
E ++ + LT +L E + + + ++L +LE V + +
Sbjct: 1406 AGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEK 1465
Query: 631 KISE----LEEELKVVGNSLKSLEVSEEKANQR 717
K + L EE V +++ E +E + +R
Sbjct: 1466 KQRKFDQLLAEEKAAVLRAVEERERAEAEGRER 1498
Score = 35.5 bits (78), Expect = 0.19
Identities = 28/158 (17%), Positives = 68/158 (43%)
Frame = +1
Query: 247 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 426
+++L + K +E EK + E + L ++ + ++ E+ + G +++L A A
Sbjct: 1057 RDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARA 1116
Query: 427 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
++ L ++ + + + L+ R+ A+ + ++ +L + ELE
Sbjct: 1117 EDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTL 1176
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
D + S+ E+E+ + +L+ E A Q +
Sbjct: 1177 DSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQEL 1214
Score = 32.7 bits (71), Expect = 1.4
Identities = 31/123 (25%), Positives = 51/123 (41%), Gaps = 3/123 (2%)
Frame = +1
Query: 190 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 369
EV ELQ ++AQ+EE+ +L + E E+ A L V ++E + +
Sbjct: 891 EVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGE 950
Query: 370 SEERSGTAQQKLLEAQQSADENNRMCKVLE---NRAQQDEERMDQLTNQLKEARLLAEDA 540
EE S Q + QQ E + E + Q ++ + + +E LL ED
Sbjct: 951 EEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQ 1010
Query: 541 DGK 549
+ K
Sbjct: 1011 NSK 1013
>AL834265-1|CAD38940.1| 505|Homo sapiens hypothetical protein
protein.
Length = 505
Score = 54.4 bits (125), Expect = 4e-07
Identities = 49/223 (21%), Positives = 106/223 (47%), Gaps = 8/223 (3%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAM-DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
KK ++ + + + + ++ E +D R K + +REL+ KL+ VEE+L K +
Sbjct: 84 KKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQE 143
Query: 256 L-----EQANKDLE--EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 414
+ E + D+E EKEK + + +VA L ++++ ++ + +++E T Q++ +
Sbjct: 144 VLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVL 203
Query: 415 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 594
+++ ++N L E + L+ +L +A + + G + KL
Sbjct: 204 EENGEKNQVQLGKL-------EATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVT 256
Query: 595 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
E + + K+ + ++EL+ VG SL+ E K +++E
Sbjct: 257 IQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLE 299
Score = 30.7 bits (66), Expect = 5.5
Identities = 25/96 (26%), Positives = 45/96 (46%), Gaps = 3/96 (3%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQ---KKLAQVEEDLI 240
+ IKK +K K QQ + + EK+ +E +ELQ + L E+++
Sbjct: 233 EIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVC 292
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQ 348
+ +LE K LEE ++ L E + LN+++ +
Sbjct: 293 KLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNE 328
>AL445928-1|CAH72248.1| 657|Homo sapiens novel protein protein.
Length = 657
Score = 54.4 bits (125), Expect = 4e-07
Identities = 49/223 (21%), Positives = 106/223 (47%), Gaps = 8/223 (3%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAM-DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
KK ++ + + + + ++ E +D R K + +REL+ KL+ VEE+L K +
Sbjct: 236 KKDLEILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQE 295
Query: 256 L-----EQANKDLE--EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 414
+ E + D+E EKEK + + +VA L ++++ ++ + +++E T Q++ +
Sbjct: 296 VLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVL 355
Query: 415 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 594
+++ ++N L E + L+ +L +A + + G + KL
Sbjct: 356 EENGEKNQVQLGKL-------EATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVT 408
Query: 595 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
E + + K+ + ++EL+ VG SL+ E K +++E
Sbjct: 409 IQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLE 451
Score = 30.7 bits (66), Expect = 5.5
Identities = 25/96 (26%), Positives = 45/96 (46%), Gaps = 3/96 (3%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQ---KKLAQVEEDLI 240
+ IKK +K K QQ + + EK+ +E +ELQ + L E+++
Sbjct: 385 EIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVC 444
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQ 348
+ +LE K LEE ++ L E + LN+++ +
Sbjct: 445 KLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNE 480
>AL049795-2|CAI22055.1| 546|Homo sapiens novel protein protein.
Length = 546
Score = 54.4 bits (125), Expect = 4e-07
Identities = 47/213 (22%), Positives = 102/213 (47%), Gaps = 7/213 (3%)
Frame = +1
Query: 88 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 267
+Q + E++ + + D L+ E+ NE +L+++ ++ E L K +EQ
Sbjct: 260 VQRAREEEEKRKEVTSHFQVTLNDIQLQMEQHNERNSKLRQENMELAERL---KKLIEQY 316
Query: 268 NKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMC 447
E +K + + ++ K+QQ +E L+++EER + LL + A E+ RMC
Sbjct: 317 ELREEHIDKVFKHKDLQQQLVDAKLQQAQEMLKEAEERHQREKDFLL---KEAVESQRMC 373
Query: 448 KVL---ENRAQQD----EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
+++ E +Q E+ ++ N L ++ + + +++++K+ +E E +
Sbjct: 374 ELMKQQETHLKQQLALYTEKFEEFQNTLSKSSEVFTTFKQEMEKMTKKIKKLEKETTMYR 433
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
R +S + + E+ EE V L+ L+V ++
Sbjct: 434 SRWESSNKALLEMAEEKTVRDKELEGLQVKIQR 466
Score = 38.3 bits (85), Expect = 0.028
Identities = 15/57 (26%), Positives = 37/57 (64%)
Frame = +1
Query: 187 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE 357
+E+ ++ KK+ ++E++ + +++ E +NK L E ++ T + E+ L K+Q++E+
Sbjct: 413 QEMEKMTKKIKKLEKETTMYRSRWESSNKALLEMAEEKTVRDKELEGLQVKIQRLEK 469
>AK023943-1|BAB14735.1| 545|Homo sapiens protein ( Homo sapiens
cDNA FLJ13881 fis, clone THYRO1001458, moderately
similar to MYOSIN HEAVY CHAIN, NONMUSCLE TYPE B. ).
Length = 545
Score = 54.4 bits (125), Expect = 4e-07
Identities = 51/224 (22%), Positives = 98/224 (43%), Gaps = 8/224 (3%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
+++++ A + A D + + NL + EE R+L+ +L Q+EE+L ++
Sbjct: 259 LQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSN 318
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
E N + Q+ + E++A + E ++ E + + +L E A
Sbjct: 319 SELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARAR 378
Query: 436 NRMC-KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV------SRKLAF-VEDE 591
++M LE++ Q EE+++Q T + + L A+ + EV R++A + D+
Sbjct: 379 HKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQ 438
Query: 592 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
LE RVK ++ E EEE + L+ E + E
Sbjct: 439 LEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAE 482
Score = 41.5 bits (93), Expect = 0.003
Identities = 28/126 (22%), Positives = 57/126 (45%)
Frame = +1
Query: 319 VAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQL 498
V+ L +K ++ ++ L + + A ++ A+ E L ++++E ++L
Sbjct: 10 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 69
Query: 499 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL 678
Q + R E D+V + + +E VAE A+++ELE+EL ++
Sbjct: 70 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK 129
Query: 679 KSLEVS 696
LEV+
Sbjct: 130 LRLEVT 135
Score = 35.5 bits (78), Expect = 0.19
Identities = 29/115 (25%), Positives = 53/115 (46%), Gaps = 4/115 (3%)
Frame = +1
Query: 277 LEEKEKQLTATEAEV-AALNRKVQQIEEDLEKSEERSGTA---QQKLLEAQQSADENNRM 444
LE+K+++ AE AA+ R V++ E + ER A + L E Q++ +E R
Sbjct: 13 LEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQ 72
Query: 445 CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 609
+ L + D + + E A+ ++++ ++ +EDEL AED
Sbjct: 73 NRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAED 127
>AF516206-1|AAO42465.1| 546|Homo sapiens taxilin protein.
Length = 546
Score = 54.4 bits (125), Expect = 4e-07
Identities = 47/213 (22%), Positives = 102/213 (47%), Gaps = 7/213 (3%)
Frame = +1
Query: 88 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 267
+Q + E++ + + D L+ E+ NE +L+++ ++ E L K +EQ
Sbjct: 260 VQRAREEEEKRKEVTSHFQVTLNDIQLQMEQHNERNSKLRQENMELAERL---KKLIEQY 316
Query: 268 NKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMC 447
E +K + + ++ K+QQ +E L+++EER + LL + A E+ RMC
Sbjct: 317 ELREEHIDKVFKHKDLQQQLVDAKLQQAQEMLKEAEERHQREKDFLL---KEAVESQRMC 373
Query: 448 KVL---ENRAQQD----EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
+++ E +Q E+ ++ N L ++ + + +++++K+ +E E +
Sbjct: 374 ELMKQQETHLKQQLALYTEKFEEFQNTLSKSSEVFTTFKQEMEKMTKKIKKLEKETTMYR 433
Query: 607 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
R +S + + E+ EE V L+ L+V ++
Sbjct: 434 SRWESSNKALLEMAEEKTVRDKELEGLQVKIQR 466
Score = 38.3 bits (85), Expect = 0.028
Identities = 15/57 (26%), Positives = 37/57 (64%)
Frame = +1
Query: 187 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE 357
+E+ ++ KK+ ++E++ + +++ E +NK L E ++ T + E+ L K+Q++E+
Sbjct: 413 QEMEKMTKKIKKLEKETTMYRSRWESSNKALLEMAEEKTVRDKELEGLQVKIQRLEK 469
>AB111886-1|BAC98374.1| 1571|Homo sapiens KIAA2034 protein protein.
Length = 1571
Score = 54.4 bits (125), Expect = 4e-07
Identities = 51/224 (22%), Positives = 98/224 (43%), Gaps = 8/224 (3%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
+++++ A + A D + + NL + EE R+L+ +L Q+EE+L ++
Sbjct: 1285 LQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSN 1344
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
E N + Q+ + E++A + E ++ E + + +L E A
Sbjct: 1345 SELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARAR 1404
Query: 436 NRMC-KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV------SRKLAF-VEDE 591
++M LE++ Q EE+++Q T + + L A+ + EV R++A + D+
Sbjct: 1405 HKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQ 1464
Query: 592 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
LE RVK ++ E EEE + L+ E + E
Sbjct: 1465 LEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAE 1508
Score = 52.0 bits (119), Expect = 2e-06
Identities = 42/185 (22%), Positives = 85/185 (45%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
E+ R A AE + + + E + + ++E + +L+ A DLE+ ++QL +T
Sbjct: 984 EEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQ-QRQLVST---- 1038
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
L +K ++ ++ L + + A ++ A+ E L ++++E ++L
Sbjct: 1039 --LEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELE 1096
Query: 502 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 681
Q + R E D+V + + +E VAE A+++ELE+EL ++
Sbjct: 1097 RQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKL 1156
Query: 682 SLEVS 696
LEV+
Sbjct: 1157 RLEVT 1161
Score = 50.4 bits (115), Expect = 6e-06
Identities = 39/173 (22%), Positives = 74/173 (42%), Gaps = 1/173 (0%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
E+Q RD E + E+ + +E + ++ + K LEE+ + A E+
Sbjct: 731 EKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQEL 790
Query: 322 AALN-RKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQL 498
+ + + ++ E LE++ G ++ L + E L+ Q+ E+R +L
Sbjct: 791 RQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRL 850
Query: 499 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 657
QL+E + A D + E + KL + ELE + ++K L +EL
Sbjct: 851 ELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKEL 903
Score = 44.8 bits (101), Expect = 3e-04
Identities = 50/228 (21%), Positives = 100/228 (43%), Gaps = 3/228 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDK-ADTCEQQARDAN-LRAE-KVNEEVRELQKKLA 219
Q +A + +++ Q E + A E++AR A LRAE ++ E E + +LA
Sbjct: 448 QARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLA 507
Query: 220 QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 399
+++L L ++LE + EE +Q+ + E L + +Q++E LE E Q
Sbjct: 508 ARKQELELVVSELEARVGEEEECSRQM---QTEKKRLQQHIQELEAHLEAEEGARQKLQL 564
Query: 400 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 579
+ + + + +LE++ + + L ++L E A + + K +++
Sbjct: 565 EKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLK 624
Query: 580 VEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
E + EDR++ + ELE+ + + L+ + QR E
Sbjct: 625 YEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAE 672
Score = 44.8 bits (101), Expect = 3e-04
Identities = 43/228 (18%), Positives = 98/228 (42%), Gaps = 4/228 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQA--MKLEKDNAM--DKADTCEQQARDANLRAEKVNEEVRELQKKL 216
Q + T +A KK + + LE N+ + E + + + +A + E+V+ L K
Sbjct: 563 QLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLR 622
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 396
+ E + +++L + K +E EK + E + L ++ + ++ E+ + G +
Sbjct: 623 LKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKE 682
Query: 397 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLA 576
++L A A++ L ++ + + + L+ R+ A+ + ++ +L
Sbjct: 683 EELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELE 742
Query: 577 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ ELE D + S+ E+E+ + +L+ E A Q +
Sbjct: 743 ALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQEL 790
Score = 42.7 bits (96), Expect = 0.001
Identities = 33/174 (18%), Positives = 75/174 (43%)
Frame = +1
Query: 88 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 267
++A + + A +A+ Q+ + +++ R LQ++L DL + +
Sbjct: 980 LEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTL 1039
Query: 268 NKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMC 447
K + ++ L +A V + ++ E + + E R+ + + L E Q++ +E R
Sbjct: 1040 EKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQN 1099
Query: 448 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 609
+ L + D + + E A+ ++++ ++ +EDEL AED
Sbjct: 1100 RALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAED 1153
Score = 41.1 bits (92), Expect = 0.004
Identities = 44/213 (20%), Positives = 92/213 (43%), Gaps = 11/213 (5%)
Frame = +1
Query: 112 DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKE 291
D +A+ E+ R A E V+ + E + K ++ ++L + +L A + L+E+
Sbjct: 863 DGERARAEAAEKLQR-AQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEET 921
Query: 292 K-------QLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 450
+ ++ A EAE A L ++++ E++ TAQ +L E ++ +E +
Sbjct: 922 RAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALE 981
Query: 451 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDA 630
E ++ + LT +L E + + + ++L +LE V + +
Sbjct: 982 AGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEK 1041
Query: 631 KISE----LEEELKVVGNSLKSLEVSEEKANQR 717
K + L EE V +++ E +E + +R
Sbjct: 1042 KQRKFDQLLAEEKAAVLRAVEERERAEAEGRER 1074
Score = 36.7 bits (81), Expect = 0.084
Identities = 54/231 (23%), Positives = 106/231 (45%), Gaps = 28/231 (12%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDK----ADTC-EQQARDANLRAEKVNEE--VRELQ 207
QQ A + ++ ++ ++ E+ ++ A+ C E + L A K E V EL+
Sbjct: 462 QQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELE 521
Query: 208 KKLAQVEE---DLILNKNKLEQANKDLEE----KEKQLTATEAEVAALNRKVQQIEEDLE 366
++ + EE + K +L+Q ++LE +E + E K+++ EEDL
Sbjct: 522 ARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLL 581
Query: 367 KSEERSG--TAQQKLLE------AQQSADENNRMCKVLENRAQQD------EERMDQLTN 504
E+++ + ++KLLE + Q+A+E ++ + + R + + E+R+ +
Sbjct: 582 LLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEK 641
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 657
+E L DG+S E+ ++ VE + E R + G K EL+ L
Sbjct: 642 GRQELEKLKRRLDGESSELQEQM--VEQQQRAEELRAQLG-RKEEELQAAL 689
>X06976-1|CAA30039.1| 543|Homo sapiens beta myosin heavy chain (
544 AA) protein.
Length = 543
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/203 (21%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 30 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 89
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 90 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 149
Query: 502 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISEL 645
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 150 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 209
Query: 646 EEELKVVGNSLKSLEVSEEKANQ 714
+ E + +L+ + E N+
Sbjct: 210 DAETRSRNEALRVKKKMEGDLNE 232
Score = 53.2 bits (122), Expect = 9e-07
Identities = 56/230 (24%), Positives = 114/230 (49%), Gaps = 14/230 (6%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 243
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 134 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 190
Query: 244 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 411
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 191 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 246
Query: 412 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 564
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 247 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 306
Query: 565 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
RKLA + EL +RV+ ++ + L + K + L L+ E+A Q
Sbjct: 307 RKLA--DRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQ 354
Score = 43.6 bits (98), Expect = 7e-04
Identities = 39/141 (27%), Positives = 67/141 (47%), Gaps = 3/141 (2%)
Frame = +1
Query: 277 LEEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSGTAQQKLLEAQQSADENNRMC 447
L+E E+ + A A+ ++L + +++ EDL ERS A L + Q++ D
Sbjct: 5 LQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFD------ 58
Query: 448 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 627
K+L Q+ EE +L + KEAR L+ + + L + LE + K+
Sbjct: 59 KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESL----EHLETFKRENKNLQ 114
Query: 628 AKISELEEELKVVGNSLKSLE 690
+IS+L E+L G ++ LE
Sbjct: 115 EEISDLTEQLGSSGKTIHELE 135
>U22816-1|AAC50173.1| 1202|Homo sapiens LAR-interacting protein 1b
protein.
Length = 1202
Score = 54.0 bits (124), Expect = 5e-07
Identities = 45/183 (24%), Positives = 86/183 (46%), Gaps = 1/183 (0%)
Frame = +1
Query: 178 KVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE 357
++ E + + ++ +Q++E L + + + +DL+ K L +E L R V++
Sbjct: 254 ELQEIISKQSREQSQMKERLASLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMA 313
Query: 358 DLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 537
E EER T +++ L AQ+ A + + LEN + Q ++ ++ + E
Sbjct: 314 QKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLEL 373
Query: 538 ADGKSDEVSRKL-AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
A+ K + RK E E E+A+ RV A +S+ EE + L+ +E E+ NQ
Sbjct: 374 AEQKLQQTLRKAETLPEVEAELAQ-RV----AALSKAEERHGNIEERLRQMEAQLEEKNQ 428
Query: 715 RVE 723
++
Sbjct: 429 ELQ 431
Score = 42.7 bits (96), Expect = 0.001
Identities = 38/170 (22%), Positives = 83/170 (48%), Gaps = 10/170 (5%)
Frame = +1
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-------KSEERS 384
EEDL K+ + + + ++ ++ + + +A+L+ V ++EEDL+ KSEE +
Sbjct: 246 EEDLA----KVIELQEIISKQSREQSQMKERLASLSSHVTELEEDLDTARKDLIKSEEMN 301
Query: 385 GTAQQKLLEAQQSADENNRMCKVLENR---AQQDEERMDQLTNQLKEARLLAEDADGKSD 555
Q+ + EA ++ LE R AQ++ + L ++L+ + +++
Sbjct: 302 TKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTE 361
Query: 556 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+ +R+L ++ LE+AE +++ K L E + + +L +EE+
Sbjct: 362 DKNRQL---QERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEER 408
Score = 37.5 bits (83), Expect = 0.048
Identities = 37/199 (18%), Positives = 81/199 (40%), Gaps = 3/199 (1%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
+K+++ ++ + DT + + K+ +VRE + +EE + + +
Sbjct: 269 MKERLASLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKR 328
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
A ++ E E+A + +Q E+ + +ER A+QKL + + A+
Sbjct: 329 YLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETL 388
Query: 436 NRMCKVLENRA---QQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
+ L R + EER + +L++ E+ + + ++ E+ +
Sbjct: 389 PEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLS 448
Query: 607 DRVKSGDAKISELEEELKV 663
D V D +SE E L++
Sbjct: 449 DTV---DKLLSESNERLQL 464
>U22815-1|AAC50172.1| 1185|Homo sapiens LAR-interacting protein 1a
protein.
Length = 1185
Score = 54.0 bits (124), Expect = 5e-07
Identities = 45/183 (24%), Positives = 86/183 (46%), Gaps = 1/183 (0%)
Frame = +1
Query: 178 KVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE 357
++ E + + ++ +Q++E L + + + +DL+ K L +E L R V++
Sbjct: 254 ELQEIISKQSREQSQMKERLASLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMA 313
Query: 358 DLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 537
E EER T +++ L AQ+ A + + LEN + Q ++ ++ + E
Sbjct: 314 QKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLEL 373
Query: 538 ADGKSDEVSRKL-AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
A+ K + RK E E E+A+ RV A +S+ EE + L+ +E E+ NQ
Sbjct: 374 AEQKLQQTLRKAETLPEVEAELAQ-RV----AALSKAEERHGNIEERLRQMEAQLEEKNQ 428
Query: 715 RVE 723
++
Sbjct: 429 ELQ 431
Score = 42.7 bits (96), Expect = 0.001
Identities = 38/170 (22%), Positives = 83/170 (48%), Gaps = 10/170 (5%)
Frame = +1
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-------KSEERS 384
EEDL K+ + + + ++ ++ + + +A+L+ V ++EEDL+ KSEE +
Sbjct: 246 EEDLA----KVIELQEIISKQSREQSQMKERLASLSSHVTELEEDLDTARKDLIKSEEMN 301
Query: 385 GTAQQKLLEAQQSADENNRMCKVLENR---AQQDEERMDQLTNQLKEARLLAEDADGKSD 555
Q+ + EA ++ LE R AQ++ + L ++L+ + +++
Sbjct: 302 TKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTE 361
Query: 556 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+ +R+L ++ LE+AE +++ K L E + + +L +EE+
Sbjct: 362 DKNRQL---QERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEER 408
Score = 37.5 bits (83), Expect = 0.048
Identities = 37/199 (18%), Positives = 81/199 (40%), Gaps = 3/199 (1%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
+K+++ ++ + DT + + K+ +VRE + +EE + + +
Sbjct: 269 MKERLASLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKR 328
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
A ++ E E+A + +Q E+ + +ER A+QKL + + A+
Sbjct: 329 YLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETL 388
Query: 436 NRMCKVLENRA---QQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
+ L R + EER + +L++ E+ + + ++ E+ +
Sbjct: 389 PEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLS 448
Query: 607 DRVKSGDAKISELEEELKV 663
D V D +SE E L++
Sbjct: 449 DTV---DKLLSESNERLQL 464
>M25139-1|AAA60385.1| 611|Homo sapiens myosin heavy chain
beta-subunit protein.
Length = 611
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/203 (21%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 98 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 157
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 158 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 217
Query: 502 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISEL 645
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 218 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 277
Query: 646 EEELKVVGNSLKSLEVSEEKANQ 714
+ E + +L+ + E N+
Sbjct: 278 DAETRSRNEALRVKKKMEGDLNE 300
Score = 53.2 bits (122), Expect = 9e-07
Identities = 56/230 (24%), Positives = 114/230 (49%), Gaps = 14/230 (6%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 243
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 202 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 258
Query: 244 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 411
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 259 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 314
Query: 412 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 564
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 315 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 374
Query: 565 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
RKLA + EL +RV+ ++ + L + K + L L+ E+A Q
Sbjct: 375 RKLA--DRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQ 422
Score = 52.4 bits (120), Expect = 2e-06
Identities = 54/214 (25%), Positives = 97/214 (45%), Gaps = 7/214 (3%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 249
+A+ +Q+ + + D ++ + + + K N EV + + K E D I
Sbjct: 3 NALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY---ETDAIQRT 59
Query: 250 NKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSGTAQQKLL 408
+LE+A K L +E E+ + A A+ ++L + +++ EDL ERS A L
Sbjct: 60 EELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALD 119
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
+ Q++ D K+L Q+ EE +L + KEAR L+ + + L +
Sbjct: 120 KKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESL----E 169
Query: 589 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 690
LE + K+ +IS+L E+L G ++ LE
Sbjct: 170 HLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 203
>M21665-1|AAA36345.1| 524|Homo sapiens protein ( Human beta-myosin
heavy chain mRNA, 3' end. ).
Length = 524
Score = 54.0 bits (124), Expect = 5e-07
Identities = 39/191 (20%), Positives = 80/191 (41%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 11 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 70
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 71 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 130
Query: 502 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 681
+ L+EA E +GK + +L F + + E+ + + + L+VV +
Sbjct: 131 SALEEAEASLEHEEGKI--LRAQLEFNQIKAEIERNVAEKDEEMEQAKRNHLRVVDSLQT 188
Query: 682 SLEVSEEKANQ 714
SL+ N+
Sbjct: 189 SLDAETRSRNE 199
Score = 52.0 bits (119), Expect = 2e-06
Identities = 55/230 (23%), Positives = 113/230 (49%), Gaps = 14/230 (6%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 243
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++ +A+ +E+
Sbjct: 115 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERNVAEKDEE--- 171
Query: 244 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 411
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 172 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 227
Query: 412 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 564
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 228 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 287
Query: 565 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
RKLA E EL +RV+ ++ + L + K + L L+ E+A Q
Sbjct: 288 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQ 335
>M17712-1|AAA36343.1| 543|Homo sapiens protein ( Human cardiac
myosin heavy chain mRNA, 3' end. ).
Length = 543
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/203 (21%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 321
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 30 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 89
Query: 322 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 501
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 90 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 149
Query: 502 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISEL 645
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 150 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 209
Query: 646 EEELKVVGNSLKSLEVSEEKANQ 714
+ E + +L+ + E N+
Sbjct: 210 DAETRSRNEALRVKKKMEGDLNE 232
Score = 53.2 bits (122), Expect = 9e-07
Identities = 56/230 (24%), Positives = 114/230 (49%), Gaps = 14/230 (6%)
Frame = +1
Query: 67 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 243
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 134 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 190
Query: 244 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 411
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 191 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 246
Query: 412 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 564
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 247 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 306
Query: 565 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
RKLA + EL +RV+ ++ + L + K + L L+ E+A Q
Sbjct: 307 RKLA--DRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQ 354
Score = 43.6 bits (98), Expect = 7e-04
Identities = 39/141 (27%), Positives = 67/141 (47%), Gaps = 3/141 (2%)
Frame = +1
Query: 277 LEEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSGTAQQKLLEAQQSADENNRMC 447
L+E E+ + A A+ ++L + +++ EDL ERS A L + Q++ D
Sbjct: 5 LQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFD------ 58
Query: 448 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 627
K+L Q+ EE +L + KEAR L+ + + L + LE + K+
Sbjct: 59 KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESL----EHLETFKRENKNLQ 114
Query: 628 AKISELEEELKVVGNSLKSLE 690
+IS+L E+L G ++ LE
Sbjct: 115 EEISDLTEQLGSSGKTIHELE 135
>D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein.
Length = 1388
Score = 54.0 bits (124), Expect = 5e-07
Identities = 46/184 (25%), Positives = 87/184 (47%), Gaps = 4/184 (2%)
Frame = +1
Query: 184 NEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQL-TATEAEVAALNRKV---QQI 351
NEE +E+QKKL +EE L N++ QA ++LE+K K + T E L ++ + +
Sbjct: 439 NEESQEIQKKLYTLEEHL---SNEM-QAKEELEQKCKSVNTRLEKTAKELEEEITLRKSV 494
Query: 352 EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 531
E L + E Q K E Q+ AD + LEN +++++ L + + +++
Sbjct: 495 ESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQNSQIST 554
Query: 532 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
E + ++ A + E + A R++ A+ S+ ++L+ L+ E A
Sbjct: 555 EKVNQLQRQLDETNALLRTESDTAA-RLRKTQAESSKQIQQLESNNRDLQDKNCLLETAK 613
Query: 712 QRVE 723
++E
Sbjct: 614 LKLE 617
Score = 43.6 bits (98), Expect = 7e-04
Identities = 53/242 (21%), Positives = 111/242 (45%), Gaps = 17/242 (7%)
Frame = +1
Query: 49 QQKAATMDAIKKKM---QAMKLEKDNAMDKAD------TCE----QQARDANLRAEKV-N 186
+ K+ M ++KK+ + +K + +N + +A+ C+ QQ + L+ + V N
Sbjct: 727 EAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLN 786
Query: 187 EEVRELQKKLAQVEEDLILNKNKLE---QANKDLEEKEKQLTATEAEVAALNRKVQQIEE 357
E+VR L K+ Q + L +N L+ Q L+ EKQL + + +++
Sbjct: 787 EDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNA 846
Query: 358 DLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 537
+L K E + Q K L+ Q A++ + + + ++ +E ++ T KE + ++
Sbjct: 847 ELRK-ERQDADGQMKELQDQLEAEQ--YFSTLYKTQVRELKEECEEKTKLGKELQQKKQE 903
Query: 538 ADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+ D ++ +L + + + + + S+LE+E K+ +K LE+ E A +
Sbjct: 904 LQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKE-KI----MKELEIKEMMARHK 958
Query: 718 VE 723
E
Sbjct: 959 QE 960
Score = 38.7 bits (86), Expect = 0.021
Identities = 47/216 (21%), Positives = 90/216 (41%), Gaps = 9/216 (4%)
Frame = +1
Query: 85 KMQAMKLEKDNAMDKADTCEQQARDANLRA--EKVNEEVRELQKKLA------QVEEDLI 240
K+ LE++ A KA ++ + E +E ++E++KKL Q E+L+
Sbjct: 695 KVIQQSLEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLL 754
Query: 241 LNKNK-LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 417
L K + DL++ ++++ + LN V+ + +E+ ++ Q L
Sbjct: 755 LEAEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQT 814
Query: 418 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 597
Q + K L+ E L Q E R +DADG+ E ++D+LE
Sbjct: 815 QQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKE-------LQDQLE 867
Query: 598 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+ ++ EL+EE + K L+ +++
Sbjct: 868 AEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQE 903
>BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
family member 1 protein.
Length = 1116
Score = 54.0 bits (124), Expect = 5e-07
Identities = 53/226 (23%), Positives = 110/226 (48%), Gaps = 12/226 (5%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL-----QKKLAQVEEDLIL 243
+KK + +K+E + KA +AR + ++++ RE+ + AQ E D +L
Sbjct: 705 QKKEECLKMESQ--LKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLL 762
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
L++ + +K+K++ E +V N+KV ++ + +++S Q L EA++
Sbjct: 763 EI--LKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSA---QMLEEARRR 817
Query: 424 ADENNRMCKVLENRAQQDEERMDQLTNQLKEA-RLLAEDADGKSDEVSRKLAFVE--DEL 594
D N + L++ ++ ++R+++L L+E+ ++ AE + E S + + +EL
Sbjct: 818 EDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEEL 877
Query: 595 EVAEDRVK----SGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+A ++VK S AK+S ++ L L +L K + V
Sbjct: 878 LMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEV 923
Score = 50.4 bits (115), Expect = 6e-06
Identities = 47/225 (20%), Positives = 102/225 (45%), Gaps = 3/225 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+Q+AA + ++ EK+ ++K +Q +D E+ +L+ L E
Sbjct: 514 EQRAAILQTEVDALRLRLEEKETMLNKKT---KQIQDMAEEKGTQAGEIHDLKDMLDVKE 570
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
+ + + K+E + L +KEKQ+ ++L +V+ ++ D ++ T ++ L
Sbjct: 571 RKVNVLQKKIENLQEQLRDKEKQM-------SSLKERVKSLQADTTNTDTALTTLEEALA 623
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
E +++ + ++ E R + + E+ +++ N K+ + L E ++S K A + D
Sbjct: 624 EKERTIE------RLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLD 677
Query: 589 ELEVAEDRVKSG---DAKISELEEELKVVGNSLKSLEVSEEKANQ 714
E A SG D+++ LE L+ +E +KA++
Sbjct: 678 LKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHE 722
Score = 44.4 bits (100), Expect = 4e-04
Identities = 25/162 (15%), Positives = 76/162 (46%)
Frame = +1
Query: 175 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 354
E + ++ +++ L +EE++ + K+ + ++ EE+ KQ+ + + KV+Q++
Sbjct: 385 EMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLK 444
Query: 355 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 534
E+L E + ++K Q + + + + +++ LTNQ +++ E
Sbjct: 445 EELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIE 504
Query: 535 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 660
++ A ++ E++ R++ + +++ ++++
Sbjct: 505 VLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQ 546
Score = 38.7 bits (86), Expect = 0.021
Identities = 31/170 (18%), Positives = 77/170 (45%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
Q +A R + +N+ ++LQ L + ++ + + L ++ + E+E L E+
Sbjct: 809 QMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESART 868
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
++V+++ +EK ++ + + KL QQS E L ++ E + ++
Sbjct: 869 NAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQ 928
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 654
+ A + +DA+ E+S ++E+ + + D + +L+++
Sbjct: 929 EALLAAISEKDANIALLELSSSKKKTQEEVAALK---REKDRLVQQLKQQ 975
>BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
family member 1 protein.
Length = 1116
Score = 54.0 bits (124), Expect = 5e-07
Identities = 53/226 (23%), Positives = 110/226 (48%), Gaps = 12/226 (5%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL-----QKKLAQVEEDLIL 243
+KK + +K+E + KA +AR + ++++ RE+ + AQ E D +L
Sbjct: 705 QKKEECLKMESQ--LKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLL 762
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
L++ + +K+K++ E +V N+KV ++ + +++S Q L EA++
Sbjct: 763 EI--LKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSA---QMLEEARRR 817
Query: 424 ADENNRMCKVLENRAQQDEERMDQLTNQLKEA-RLLAEDADGKSDEVSRKLAFVE--DEL 594
D N + L++ ++ ++R+++L L+E+ ++ AE + E S + + +EL
Sbjct: 818 EDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEEL 877
Query: 595 EVAEDRVK----SGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+A ++VK S AK+S ++ L L +L K + V
Sbjct: 878 LMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEV 923
Score = 50.4 bits (115), Expect = 6e-06
Identities = 47/225 (20%), Positives = 102/225 (45%), Gaps = 3/225 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+Q+AA + ++ EK+ ++K +Q +D E+ +L+ L E
Sbjct: 514 EQRAAILQTEVDALRLRLEEKETMLNKKT---KQIQDMAEEKGTQAGEIHDLKDMLDVKE 570
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
+ + + K+E + L +KEKQ+ ++L +V+ ++ D ++ T ++ L
Sbjct: 571 RKVNVLQKKIENLQEQLRDKEKQM-------SSLKERVKSLQADTTNTDTALTTLEEALA 623
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
E +++ + ++ E R + + E+ +++ N K+ + L E ++S K A + D
Sbjct: 624 EKERTIE------RLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLD 677
Query: 589 ELEVAEDRVKSG---DAKISELEEELKVVGNSLKSLEVSEEKANQ 714
E A SG D+++ LE L+ +E +KA++
Sbjct: 678 LKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHE 722
Score = 44.4 bits (100), Expect = 4e-04
Identities = 25/162 (15%), Positives = 76/162 (46%)
Frame = +1
Query: 175 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 354
E + ++ +++ L +EE++ + K+ + ++ EE+ KQ+ + + KV+Q++
Sbjct: 385 EMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLK 444
Query: 355 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 534
E+L E + ++K Q + + + + +++ LTNQ +++ E
Sbjct: 445 EELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIE 504
Query: 535 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 660
++ A ++ E++ R++ + +++ ++++
Sbjct: 505 VLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQ 546
Score = 38.7 bits (86), Expect = 0.021
Identities = 31/170 (18%), Positives = 77/170 (45%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
Q +A R + +N+ ++LQ L + ++ + + L ++ + E+E L E+
Sbjct: 809 QMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESART 868
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
++V+++ +EK ++ + + KL QQS E L ++ E + ++
Sbjct: 869 NAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQ 928
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 654
+ A + +DA+ E+S ++E+ + + D + +L+++
Sbjct: 929 EALLAAISEKDANIALLELSSSKKKTQEEVAALK---REKDRLVQQLKQQ 975
>BC101026-1|AAI01027.1| 490|Homo sapiens SASS6 protein protein.
Length = 490
Score = 54.0 bits (124), Expect = 5e-07
Identities = 49/223 (21%), Positives = 106/223 (47%), Gaps = 8/223 (3%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAM-DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
KK ++ + + + + ++ E +D R K + +REL+ KL+ VEE+L K +
Sbjct: 69 KKDLEILHQQNIHQLQNRLSELEVANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQE 128
Query: 256 L-----EQANKDLE--EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 414
+ E + D+E EKEK + + +VA L ++++ ++ + +++E T Q++ +
Sbjct: 129 VLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVL 188
Query: 415 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 594
+++ ++N L E + L+ +L +A + + G + KL
Sbjct: 189 EENGEKNQVQLGKL-------EATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVT 241
Query: 595 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
E + + K+ + ++EL+ VG SL+ E K +++E
Sbjct: 242 IQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLE 284
Score = 30.7 bits (66), Expect = 5.5
Identities = 25/96 (26%), Positives = 45/96 (46%), Gaps = 3/96 (3%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQ---KKLAQVEEDLI 240
+ IKK +K K QQ + + EK+ +E +ELQ + L E+++
Sbjct: 218 EIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVC 277
Query: 241 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQ 348
+ +LE K LEE ++ L E + LN+++ +
Sbjct: 278 KLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNE 313
>BC034046-1|AAH34046.1| 1202|Homo sapiens protein tyrosine
phosphatase, receptor type, f polypeptide (PTPRF),
interacting protein.
Length = 1202
Score = 54.0 bits (124), Expect = 5e-07
Identities = 45/183 (24%), Positives = 86/183 (46%), Gaps = 1/183 (0%)
Frame = +1
Query: 178 KVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE 357
++ E + + ++ +Q++E L + + + +DL+ K L +E L R V++
Sbjct: 254 ELQEIISKQSREQSQMKERLASLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMA 313
Query: 358 DLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 537
E EER T +++ L AQ+ A + + LEN + Q ++ ++ + E
Sbjct: 314 QKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLEL 373
Query: 538 ADGKSDEVSRKL-AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 714
A+ K + RK E E E+A+ RV A +S+ EE + L+ +E E+ NQ
Sbjct: 374 AEQKLQQTLRKAETLPEVEAELAQ-RV----AALSKAEERHGNIEERLRQMEAQLEEKNQ 428
Query: 715 RVE 723
++
Sbjct: 429 ELQ 431
Score = 42.7 bits (96), Expect = 0.001
Identities = 38/170 (22%), Positives = 83/170 (48%), Gaps = 10/170 (5%)
Frame = +1
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-------KSEERS 384
EEDL K+ + + + ++ ++ + + +A+L+ V ++EEDL+ KSEE +
Sbjct: 246 EEDLA----KVIELQEIISKQSREQSQMKERLASLSSHVTELEEDLDTARKDLIKSEEMN 301
Query: 385 GTAQQKLLEAQQSADENNRMCKVLENR---AQQDEERMDQLTNQLKEARLLAEDADGKSD 555
Q+ + EA ++ LE R AQ++ + L ++L+ + +++
Sbjct: 302 TKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTE 361
Query: 556 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+ +R+L ++ LE+AE +++ K L E + + +L +EE+
Sbjct: 362 DKNRQL---QERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEER 408
Score = 37.5 bits (83), Expect = 0.048
Identities = 37/199 (18%), Positives = 81/199 (40%), Gaps = 3/199 (1%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
+K+++ ++ + DT + + K+ +VRE + +EE + + +
Sbjct: 269 MKERLASLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKR 328
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
A ++ E E+A + +Q E+ + +ER A+QKL + + A+
Sbjct: 329 YLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETL 388
Query: 436 NRMCKVLENRA---QQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 606
+ L R + EER + +L++ E+ + + ++ E+ +
Sbjct: 389 PEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLS 448
Query: 607 DRVKSGDAKISELEEELKV 663
D V D +SE E L++
Sbjct: 449 DTV---DKLLSESNERLQL 464
>AL121586-7|CAB89415.1| 2442|Homo sapiens centrosomal protein 250kDa
protein.
Length = 2442
Score = 54.0 bits (124), Expect = 5e-07
Identities = 49/199 (24%), Positives = 95/199 (47%), Gaps = 9/199 (4%)
Frame = +1
Query: 154 RDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALN 333
RD E E + ELQ+ Q+E+ +L+ ++ + E L+ E E+ L
Sbjct: 1732 RDKEKEVECQQEHIHELQELKDQLEQ-------QLQGLHRKVGETSLLLSQREQEIVVLQ 1784
Query: 334 RKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQ---DEERM----D 492
QQ++E E+ E + + Q +L EAQ++ + ++ + L+ QQ EER+ D
Sbjct: 1785 ---QQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKAD 1841
Query: 493 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 672
L L++A + ++ G+ + + +E+EL V RV++ + + +L E +
Sbjct: 1842 ALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEK 1901
Query: 673 SLKSL--EVSEEKANQRVE 723
+L +L + +E+ VE
Sbjct: 1902 ALLALQQQCAEQAQEHEVE 1920
Score = 47.2 bits (107), Expect = 6e-05
Identities = 53/222 (23%), Positives = 105/222 (47%), Gaps = 21/222 (9%)
Frame = +1
Query: 52 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE--KVNEEVRELQKKLAQV 225
+ A +D + + + L + N +A + + A L+A+ + EE E+QKKL++
Sbjct: 640 RNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSES 699
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLT-------ATEAEVAALNRKVQQIEEDLEK-SEER 381
+LEQ +++ + +E+ L A E AAL ++Q +E D + +E+
Sbjct: 700 RHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQL 759
Query: 382 SGTAQQK-LLEAQQ-SADENNRMCKVLENRAQQDEERMDQLTNQLK-EARLL-------A 531
G + K LLE+ A + N + +V + + + + + Q ++ E R L
Sbjct: 760 QGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTER 819
Query: 532 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAK-ISELEEE 654
A+ + D +R+LA E E + A ++ K+ K +++L E+
Sbjct: 820 SQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREK 861
Score = 46.8 bits (106), Expect = 8e-05
Identities = 47/234 (20%), Positives = 107/234 (45%), Gaps = 10/234 (4%)
Frame = +1
Query: 52 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 231
Q+ ++A++++ Q + +++ +KAD + A++ ++ + E+++ +++ ++EE
Sbjct: 1814 QRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEE 1873
Query: 232 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 411
+L + +++ + L + + E + AL QQ E ++ E + Q L+
Sbjct: 1874 ELAVEGRRVQALEEVLGDLRAESREQEKALLALQ---QQCAEQAQEHEVETRALQDSWLQ 1930
Query: 412 AQQSADENNRMCKVLENRAQ---QDEERMDQLTNQLKEARLLAEDA-DGKSD------EV 561
AQ E ++ + L +Q EE L+EA A A GK E+
Sbjct: 1931 AQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAEL 1990
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
SR L L+ + D + A +LEE L++ ++ ++ ++ Q+++
Sbjct: 1991 SRSLEASTATLQASLDACQ---AHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQ 2041
Score = 44.0 bits (99), Expect = 6e-04
Identities = 58/243 (23%), Positives = 110/243 (45%), Gaps = 29/243 (11%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQAR--DANLRAEKVN--EEVREL--QK 210
Q++ T D ++++ Q + L+K+ D +Q + + +L K++ E REL Q+
Sbjct: 1645 QKEHLTQD-LERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQR 1703
Query: 211 KLAQ--VEEDLILNK---NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 375
+L Q EE +K LE L +KEK++ + + L Q+E+ L+
Sbjct: 1704 QLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLH 1763
Query: 376 ERSGTA-------QQKLLEAQQSADENNRMCKVLEN--RAQQDEER--MDQLTNQLKEAR 522
+ G +Q+++ QQ E ++ E ++Q DE + + Q +L+ +
Sbjct: 1764 RKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQ 1823
Query: 523 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE-------LEEELKVVGNSLK 681
+ A G+ + V K ++ LE A +K ++ + LEEEL V G ++
Sbjct: 1824 QEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQ 1883
Query: 682 SLE 690
+LE
Sbjct: 1884 ALE 1886
Score = 43.2 bits (97), Expect = 0.001
Identities = 44/210 (20%), Positives = 98/210 (46%), Gaps = 3/210 (1%)
Frame = +1
Query: 94 AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 273
+ +LE+ K ++Q L+ + + E REL++ Q +DL + + +
Sbjct: 945 SQQLERLRQDMKVQKLKEQETTGILQTQ-LQEAQRELKEAARQHRDDLAALQEESSSLLQ 1003
Query: 274 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS--EERSGTAQQKLLEAQQSADENNRMC 447
D + +KQ+ ++++ A + + +E+++++ E + QK LE ++++ + M
Sbjct: 1004 DKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLME 1063
Query: 448 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 627
K Q+ + + Q +L R ++A G+ E+S ++ + E++ E + +
Sbjct: 1064 KEQRLLVLQEADSIRQ--QELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQE 1121
Query: 628 AKISELEEELKVVGNSLK-SLEVSEEKANQ 714
A++ E E + L+ SL E KA Q
Sbjct: 1122 AQLLEELEASHITEQQLRASLWAQEAKAAQ 1151
Score = 41.5 bits (93), Expect = 0.003
Identities = 36/173 (20%), Positives = 80/173 (46%), Gaps = 3/173 (1%)
Frame = +1
Query: 214 LAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 393
L ++ +DL + + +++ E++LT TEAE + ++ ++Q ++ L +++E
Sbjct: 1245 LHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQE----- 1299
Query: 394 QQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD---EVS 564
++ E +Q++ LE+ + E M L ++L+ A L +A G+ +
Sbjct: 1300 EKSKWEGKQNS---------LESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAK 1350
Query: 565 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
L + L+ A ++ + LEE+L+ ++LK E +R +
Sbjct: 1351 ENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQ 1403
Score = 38.3 bits (85), Expect = 0.028
Identities = 41/209 (19%), Positives = 98/209 (46%), Gaps = 4/209 (1%)
Frame = +1
Query: 100 KLEKDNAMDKADTCEQQARDANLRAEKVN--EEVRELQKKLAQVEEDLILNKNKLEQANK 273
+L++ + D Q ++L +K++ ++V +L+ +L ++ L + ++++ +
Sbjct: 979 ELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLR 1038
Query: 274 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV 453
+ +E + E E A+L + + E+ L +E QQ+L +Q E
Sbjct: 1039 ETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQE------- 1091
Query: 454 LENRAQQDEERMDQLTNQL--KEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 627
+ ++ +M+ L ++ KEA LA++A +E+ E +L + + + +
Sbjct: 1092 AQGEQKELSAQMELLRQEVKEKEADFLAQEAQ-LLEELEAS-HITEQQLRAS---LWAQE 1146
Query: 628 AKISELEEELKVVGNSLKSLEVSEEKANQ 714
AK ++L+ L+ + L++L ++ NQ
Sbjct: 1147 AKAAQLQLRLRSTESQLEALAAEQQPGNQ 1175
Score = 35.5 bits (78), Expect = 0.19
Identities = 39/226 (17%), Positives = 102/226 (45%), Gaps = 3/226 (1%)
Frame = +1
Query: 55 KAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED 234
K +++ +++ QA++ + + + + ++ + EEV L+ ++ ++E+
Sbjct: 1391 KNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQ 1450
Query: 235 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 414
+ K LE + DL+++ +++ + ++ L K + + E L + + +QKL
Sbjct: 1451 REMQKAALELLSLDLKKRNQEVDLQQEQIQEL-EKCRSVLEHLPMAVQE---REQKLTVQ 1506
Query: 415 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED-- 588
++ E LE + ++ +L++ + E G+ ++ ++L +E
Sbjct: 1507 REQIRE-------LEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLA 1559
Query: 589 -ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
ELE +++ I ELE + + +L L + E+ +Q ++
Sbjct: 1560 LELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQ 1605
Score = 34.3 bits (75), Expect = 0.45
Identities = 38/207 (18%), Positives = 95/207 (45%), Gaps = 16/207 (7%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKK-------LAQVEEDLILNKNKLE-------QANKDL 279
E Q RD +++++ E++ ELQ++ L + +++L+L K +++ + K L
Sbjct: 1624 ELQERDQEVKSQR--EQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKIL 1681
Query: 280 EEKEKQLTATEAEVA-ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 456
EE +Q+ + E L + Q ++E E+ + S + L + + + +
Sbjct: 1682 EEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQ 1741
Query: 457 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 636
+ + +E DQL QL+ + + +++ ++ +L+ A ++ + + +
Sbjct: 1742 QEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSL 1801
Query: 637 -SELEEELKVVGNSLKSLEVSEEKANQ 714
S+L+E + + + LE +++ Q
Sbjct: 1802 QSQLDEAQRALAQRDQELEALQQEQQQ 1828
Score = 33.5 bits (73), Expect = 0.78
Identities = 40/171 (23%), Positives = 68/171 (39%), Gaps = 16/171 (9%)
Frame = +1
Query: 187 EEVRELQK-KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 363
E RE Q+ L + DL +L+ + + + E T E+ +++V+ E +
Sbjct: 1580 EGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQI 1639
Query: 364 EKSEERSGTAQQKLLEAQQS-----------ADENNRMCKVLENRAQQDE----ERMDQL 498
E+ + + Q L Q D+ R K+LE +Q + ER +L
Sbjct: 1640 EELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGREL 1699
Query: 499 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE 651
T Q + + AE+ G S L ++ L E V+ I EL+E
Sbjct: 1700 TTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQE 1750
Score = 33.5 bits (73), Expect = 0.78
Identities = 21/121 (17%), Positives = 60/121 (49%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 249
+ + +K A +++ +N + + Q+ + +R +++ VRELQ LAQ E++++ +
Sbjct: 2058 EQLLEKSLAQRVQ-ENMIQEKQNLGQEREEEEIRG--LHQSVRELQLTLAQKEQEILELR 2114
Query: 250 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 429
++ N + + + E + L+ +++ +LE+ + + + +E ++ A
Sbjct: 2115 ETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQ 2174
Query: 430 E 432
+
Sbjct: 2175 D 2175
>AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal Nek2-associated
protein 1 protein.
Length = 2442
Score = 54.0 bits (124), Expect = 5e-07
Identities = 49/199 (24%), Positives = 95/199 (47%), Gaps = 9/199 (4%)
Frame = +1
Query: 154 RDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALN 333
RD E E + ELQ+ Q+E+ +L+ ++ + E L+ E E+ L
Sbjct: 1732 RDKEKEVECQQEHIHELQELKDQLEQ-------QLQGLHRKVGETSLLLSQREQEIVVLQ 1784
Query: 334 RKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQ---DEERM----D 492
QQ++E E+ E + + Q +L EAQ++ + ++ + L+ QQ EER+ D
Sbjct: 1785 ---QQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKAD 1841
Query: 493 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 672
L L++A + ++ G+ + + +E+EL V RV++ + + +L E +
Sbjct: 1842 ALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEK 1901
Query: 673 SLKSL--EVSEEKANQRVE 723
+L +L + +E+ VE
Sbjct: 1902 ALLALQQQCAEQAQEHEVE 1920
Score = 47.2 bits (107), Expect = 6e-05
Identities = 53/222 (23%), Positives = 105/222 (47%), Gaps = 21/222 (9%)
Frame = +1
Query: 52 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE--KVNEEVRELQKKLAQV 225
+ A +D + + + L + N +A + + A L+A+ + EE E+QKKL++
Sbjct: 640 RNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSES 699
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLT-------ATEAEVAALNRKVQQIEEDLEK-SEER 381
+LEQ +++ + +E+ L A E AAL ++Q +E D + +E+
Sbjct: 700 RHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQL 759
Query: 382 SGTAQQK-LLEAQQ-SADENNRMCKVLENRAQQDEERMDQLTNQLK-EARLL-------A 531
G + K LLE+ A + N + +V + + + + + Q ++ E R L
Sbjct: 760 QGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTER 819
Query: 532 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAK-ISELEEE 654
A+ + D +R+LA E E + A ++ K+ K +++L E+
Sbjct: 820 SQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREK 861
Score = 46.8 bits (106), Expect = 8e-05
Identities = 47/234 (20%), Positives = 107/234 (45%), Gaps = 10/234 (4%)
Frame = +1
Query: 52 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 231
Q+ ++A++++ Q + +++ +KAD + A++ ++ + E+++ +++ ++EE
Sbjct: 1814 QRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEE 1873
Query: 232 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 411
+L + +++ + L + + E + AL QQ E ++ E + Q L+
Sbjct: 1874 ELAVEGRRVQALEEVLGDLRAESREQEKALLALQ---QQCAEQAQEHEVETRALQDSWLQ 1930
Query: 412 AQQSADENNRMCKVLENRAQ---QDEERMDQLTNQLKEARLLAEDA-DGKSD------EV 561
AQ E ++ + L +Q EE L+EA A A GK E+
Sbjct: 1931 AQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAEL 1990
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
SR L L+ + D + A +LEE L++ ++ ++ ++ Q+++
Sbjct: 1991 SRSLEASTATLQASLDACQ---AHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQ 2041
Score = 44.0 bits (99), Expect = 6e-04
Identities = 58/243 (23%), Positives = 110/243 (45%), Gaps = 29/243 (11%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQAR--DANLRAEKVN--EEVREL--QK 210
Q++ T D ++++ Q + L+K+ D +Q + + +L K++ E REL Q+
Sbjct: 1645 QKEHLTQD-LERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQR 1703
Query: 211 KLAQ--VEEDLILNK---NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 375
+L Q EE +K LE L +KEK++ + + L Q+E+ L+
Sbjct: 1704 QLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLH 1763
Query: 376 ERSGTA-------QQKLLEAQQSADENNRMCKVLEN--RAQQDEER--MDQLTNQLKEAR 522
+ G +Q+++ QQ E ++ E ++Q DE + + Q +L+ +
Sbjct: 1764 RKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQ 1823
Query: 523 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE-------LEEELKVVGNSLK 681
+ A G+ + V K ++ LE A +K ++ + LEEEL V G ++
Sbjct: 1824 QEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQ 1883
Query: 682 SLE 690
+LE
Sbjct: 1884 ALE 1886
Score = 43.2 bits (97), Expect = 0.001
Identities = 44/210 (20%), Positives = 98/210 (46%), Gaps = 3/210 (1%)
Frame = +1
Query: 94 AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 273
+ +LE+ K ++Q L+ + + E REL++ Q +DL + + +
Sbjct: 945 SQQLERLRQDMKVQKLKEQETTGILQTQ-LQEAQRELKEAARQHRDDLAALQEESSSLLQ 1003
Query: 274 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS--EERSGTAQQKLLEAQQSADENNRMC 447
D + +KQ+ ++++ A + + +E+++++ E + QK LE ++++ + M
Sbjct: 1004 DKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLME 1063
Query: 448 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 627
K Q+ + + Q +L R ++A G+ E+S ++ + E++ E + +
Sbjct: 1064 KEQRLLVLQEADSIRQ--QELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQE 1121
Query: 628 AKISELEEELKVVGNSLK-SLEVSEEKANQ 714
A++ E E + L+ SL E KA Q
Sbjct: 1122 AQLLEELEASHITEQQLRASLWAQEAKAAQ 1151
Score = 41.5 bits (93), Expect = 0.003
Identities = 36/173 (20%), Positives = 80/173 (46%), Gaps = 3/173 (1%)
Frame = +1
Query: 214 LAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 393
L ++ +DL + + +++ E++LT TEAE + ++ ++Q ++ L +++E
Sbjct: 1245 LHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQE----- 1299
Query: 394 QQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD---EVS 564
++ E +Q++ LE+ + E M L ++L+ A L +A G+ +
Sbjct: 1300 EKSKWEGKQNS---------LESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAK 1350
Query: 565 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
L + L+ A ++ + LEE+L+ ++LK E +R +
Sbjct: 1351 ENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQ 1403
Score = 38.3 bits (85), Expect = 0.028
Identities = 41/209 (19%), Positives = 98/209 (46%), Gaps = 4/209 (1%)
Frame = +1
Query: 100 KLEKDNAMDKADTCEQQARDANLRAEKVN--EEVRELQKKLAQVEEDLILNKNKLEQANK 273
+L++ + D Q ++L +K++ ++V +L+ +L ++ L + ++++ +
Sbjct: 979 ELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLR 1038
Query: 274 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV 453
+ +E + E E A+L + + E+ L +E QQ+L +Q E
Sbjct: 1039 ETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQE------- 1091
Query: 454 LENRAQQDEERMDQLTNQL--KEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 627
+ ++ +M+ L ++ KEA LA++A +E+ E +L + + + +
Sbjct: 1092 AQGEQKELSAQMELLRQEVKEKEADFLAQEAQ-LLEELEAS-HITEQQLRAS---LWAQE 1146
Query: 628 AKISELEEELKVVGNSLKSLEVSEEKANQ 714
AK ++L+ L+ + L++L ++ NQ
Sbjct: 1147 AKAAQLQLRLRSTESQLEALAAEQQPGNQ 1175
Score = 35.5 bits (78), Expect = 0.19
Identities = 39/226 (17%), Positives = 102/226 (45%), Gaps = 3/226 (1%)
Frame = +1
Query: 55 KAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED 234
K +++ +++ QA++ + + + + ++ + EEV L+ ++ ++E+
Sbjct: 1391 KNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQ 1450
Query: 235 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 414
+ K LE + DL+++ +++ + ++ L K + + E L + + +QKL
Sbjct: 1451 REMQKAALELLSLDLKKRNQEVDLQQEQIQEL-EKCRSVLEHLPMAVQE---REQKLTVQ 1506
Query: 415 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED-- 588
++ E LE + ++ +L++ + E G+ ++ ++L +E
Sbjct: 1507 REQIRE-------LEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLA 1559
Query: 589 -ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
ELE +++ I ELE + + +L L + E+ +Q ++
Sbjct: 1560 LELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQ 1605
Score = 34.3 bits (75), Expect = 0.45
Identities = 38/207 (18%), Positives = 95/207 (45%), Gaps = 16/207 (7%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKK-------LAQVEEDLILNKNKLE-------QANKDL 279
E Q RD +++++ E++ ELQ++ L + +++L+L K +++ + K L
Sbjct: 1624 ELQERDQEVKSQR--EQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKIL 1681
Query: 280 EEKEKQLTATEAEVA-ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 456
EE +Q+ + E L + Q ++E E+ + S + L + + + +
Sbjct: 1682 EEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQ 1741
Query: 457 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 636
+ + +E DQL QL+ + + +++ ++ +L+ A ++ + + +
Sbjct: 1742 QEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSL 1801
Query: 637 -SELEEELKVVGNSLKSLEVSEEKANQ 714
S+L+E + + + LE +++ Q
Sbjct: 1802 QSQLDEAQRALAQRDQELEALQQEQQQ 1828
Score = 33.5 bits (73), Expect = 0.78
Identities = 40/171 (23%), Positives = 68/171 (39%), Gaps = 16/171 (9%)
Frame = +1
Query: 187 EEVRELQK-KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 363
E RE Q+ L + DL +L+ + + + E T E+ +++V+ E +
Sbjct: 1580 EGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQI 1639
Query: 364 EKSEERSGTAQQKLLEAQQS-----------ADENNRMCKVLENRAQQDE----ERMDQL 498
E+ + + Q L Q D+ R K+LE +Q + ER +L
Sbjct: 1640 EELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGREL 1699
Query: 499 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE 651
T Q + + AE+ G S L ++ L E V+ I EL+E
Sbjct: 1700 TTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQE 1750
Score = 33.5 bits (73), Expect = 0.78
Identities = 21/121 (17%), Positives = 60/121 (49%)
Frame = +1
Query: 70 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 249
+ + +K A +++ +N + + Q+ + +R +++ VRELQ LAQ E++++ +
Sbjct: 2058 EQLLEKSLAQRVQ-ENMIQEKQNLGQEREEEEIRG--LHQSVRELQLTLAQKEQEILELR 2114
Query: 250 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 429
++ N + + + E + L+ +++ +LE+ + + + +E ++ A
Sbjct: 2115 ETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQ 2174
Query: 430 E 432
+
Sbjct: 2175 D 2175
>AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome associated
protein protein.
Length = 2442
Score = 54.0 bits (124), Expect = 5e-07
Identities = 49/199 (24%), Positives = 95/199 (47%), Gaps = 9/199 (4%)
Frame = +1
Query: 154 RDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALN 333
RD E E + ELQ+ Q+E+ +L+ ++ + E L+ E E+ L
Sbjct: 1732 RDKEKEVECQQEHIHELQELKDQLEQ-------QLQGLHRKVGETSLLLSQREQEIVVLQ 1784
Query: 334 RKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQ---DEERM----D 492
QQ++E E+ E + + Q +L EAQ++ + ++ + L+ QQ EER+ D
Sbjct: 1785 ---QQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKAD 1841
Query: 493 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 672
L L++A + ++ G+ + + +E+EL V RV++ + + +L E +
Sbjct: 1842 ALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEK 1901
Query: 673 SLKSL--EVSEEKANQRVE 723
+L +L + +E+ VE
Sbjct: 1902 ALLALQQQCAEQAQEHEVE 1920
Score = 46.8 bits (106), Expect = 8e-05
Identities = 47/234 (20%), Positives = 107/234 (45%), Gaps = 10/234 (4%)
Frame = +1
Query: 52 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 231
Q+ ++A++++ Q + +++ +KAD + A++ ++ + E+++ +++ ++EE
Sbjct: 1814 QRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEE 1873
Query: 232 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 411
+L + +++ + L + + E + AL QQ E ++ E + Q L+
Sbjct: 1874 ELAVEGRRVQALEEVLGDLRAESREQEKALLALQ---QQCAEQAQEHEVETRALQDSWLQ 1930
Query: 412 AQQSADENNRMCKVLENRAQ---QDEERMDQLTNQLKEARLLAEDA-DGKSD------EV 561
AQ E ++ + L +Q EE L+EA A A GK E+
Sbjct: 1931 AQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAEL 1990
Query: 562 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
SR L L+ + D + A +LEE L++ ++ ++ ++ Q+++
Sbjct: 1991 SRSLEASTATLQASLDACQ---AHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQ 2041
Score = 44.0 bits (99), Expect = 6e-04
Identities = 55/222 (24%), Positives = 99/222 (44%), Gaps = 21/222 (9%)
Frame = +1
Query: 52 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE--KVNEEVRELQKKLAQV 225
+ A +D + + + L + N +A + + A L+A+ + EE E+QKKL++
Sbjct: 640 RNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSES 699
Query: 226 EEDLILNKNKLEQANKDLEEKEKQLT-------ATEAEVAALNRKVQQIEEDLEK-SEER 381
+LEQ +++ + +E+ L A E AAL ++Q +E D + + +
Sbjct: 700 RHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAAQL 759
Query: 382 SGTAQQK------LLEAQQS---ADENNRMCKVLENRAQQDEERMDQLTNQLK-EARLLA 531
G + K L EAQQ DE +V Q +E + LK E
Sbjct: 760 QGLSSAKELLESSLFEAQQQNSVIDEPQGQLEVQIQTVTQAKEVIQGEVRCLKLELDTER 819
Query: 532 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAK-ISELEEE 654
A+ + D +R+LA E E + A ++ K+ K +++L E+
Sbjct: 820 SQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREK 861
Score = 44.0 bits (99), Expect = 6e-04
Identities = 58/243 (23%), Positives = 110/243 (45%), Gaps = 29/243 (11%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQAR--DANLRAEKVN--EEVREL--QK 210
Q++ T D ++++ Q + L+K+ D +Q + + +L K++ E REL Q+
Sbjct: 1645 QKEHLTQD-LERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQR 1703
Query: 211 KLAQ--VEEDLILNK---NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 375
+L Q EE +K LE L +KEK++ + + L Q+E+ L+
Sbjct: 1704 QLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLH 1763
Query: 376 ERSGTA-------QQKLLEAQQSADENNRMCKVLEN--RAQQDEER--MDQLTNQLKEAR 522
+ G +Q+++ QQ E ++ E ++Q DE + + Q +L+ +
Sbjct: 1764 RKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQ 1823
Query: 523 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE-------LEEELKVVGNSLK 681
+ A G+ + V K ++ LE A +K ++ + LEEEL V G ++
Sbjct: 1824 QEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQ 1883
Query: 682 SLE 690
+LE
Sbjct: 1884 ALE 1886
Score = 43.2 bits (97), Expect = 0.001
Identities = 44/210 (20%), Positives = 98/210 (46%), Gaps = 3/210 (1%)
Frame = +1
Query: 94 AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 273
+ +LE+ K ++Q L+ + + E REL++ Q +DL + + +
Sbjct: 945 SQQLERLRQDMKVQKLKEQETTGILQTQ-LQEAQRELKEAARQHRDDLAALQEESSSLLQ 1003
Query: 274 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS--EERSGTAQQKLLEAQQSADENNRMC 447
D + +KQ+ ++++ A + + +E+++++ E + QK LE ++++ + M
Sbjct: 1004 DKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLME 1063
Query: 448 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 627
K Q+ + + Q +L R ++A G+ E+S ++ + E++ E + +
Sbjct: 1064 KEQRLLVLQEADSIRQ--QELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQE 1121
Query: 628 AKISELEEELKVVGNSLK-SLEVSEEKANQ 714
A++ E E + L+ SL E KA Q
Sbjct: 1122 AQLLEELEASHITEQQLRASLWAQEAKAAQ 1151
Score = 41.9 bits (94), Expect = 0.002
Identities = 36/173 (20%), Positives = 80/173 (46%), Gaps = 3/173 (1%)
Frame = +1
Query: 214 LAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 393
L ++ +DL + + +++ E++LT TEAE + ++ ++Q ++ L +++E
Sbjct: 1245 LLKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQE----- 1299
Query: 394 QQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD---EVS 564
++ E +Q++ LE+ + E M L ++L+ A L +A G+ +
Sbjct: 1300 EKSKWEGKQNS---------LESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAK 1350
Query: 565 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
L + L+ A ++ + LEE+L+ ++LK E +R +
Sbjct: 1351 ENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQ 1403
Score = 37.5 bits (83), Expect = 0.048
Identities = 41/209 (19%), Positives = 97/209 (46%), Gaps = 4/209 (1%)
Frame = +1
Query: 100 KLEKDNAMDKADTCEQQARDANLRAEKVN--EEVRELQKKLAQVEEDLILNKNKLEQANK 273
+L++ + D Q ++L +K++ ++V +L+ +L ++ L + ++++ +
Sbjct: 979 ELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLR 1038
Query: 274 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV 453
+ +E + E E A+L + + E+ L +E QQ+L +Q E
Sbjct: 1039 ETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQE------- 1091
Query: 454 LENRAQQDEERMDQLTNQL--KEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 627
+ ++ +M+ L ++ KEA LA++A +E+ E +L + + + +
Sbjct: 1092 AQGEQKELSAQMELLRQEVKEKEADFLAQEAQ-LLEELEAS-HITEQQLRAS---LWAQE 1146
Query: 628 AKISELEEELKVVGNSLKSLEVSEEKANQ 714
AK ++L L+ + L++L ++ NQ
Sbjct: 1147 AKAAQLHLRLRSTESQLEALAAEQQPGNQ 1175
Score = 35.1 bits (77), Expect = 0.26
Identities = 42/226 (18%), Positives = 104/226 (46%), Gaps = 3/226 (1%)
Frame = +1
Query: 55 KAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED 234
K +++ +++ QA++ + + + + ++ + EEV L+ ++ ++E+
Sbjct: 1391 KNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQ 1450
Query: 235 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE---KSEERSGTAQQKL 405
+ K LE + DL+++ +++ + ++ L K + + E L + E+ T Q++
Sbjct: 1451 REMQKAALELLSLDLKKRNQEVDLQQEQIQEL-EKCRSVLEHLPMAVQEREQKLTVQREQ 1509
Query: 406 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 585
+ + E R VLE++ + E++ + +Q + + D K V+ L +
Sbjct: 1510 IREPEKDRETQR--NVLEHQLLELEKKDQMIESQRGQVQ------DLKKQLVT--LECLA 1559
Query: 586 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
ELE +++ I ELE + + +L L + E+ +Q ++
Sbjct: 1560 LELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQ 1605
Score = 34.3 bits (75), Expect = 0.45
Identities = 38/207 (18%), Positives = 95/207 (45%), Gaps = 16/207 (7%)
Frame = +1
Query: 142 EQQARDANLRAEKVNEEVRELQKK-------LAQVEEDLILNKNKLE-------QANKDL 279
E Q RD +++++ E++ ELQ++ L + +++L+L K +++ + K L
Sbjct: 1624 ELQERDQEVKSQR--EQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKIL 1681
Query: 280 EEKEKQLTATEAEVA-ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 456
EE +Q+ + E L + Q ++E E+ + S + L + + + +
Sbjct: 1682 EEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQ 1741
Query: 457 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 636
+ + +E DQL QL+ + + +++ ++ +L+ A ++ + + +
Sbjct: 1742 QEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSL 1801
Query: 637 -SELEEELKVVGNSLKSLEVSEEKANQ 714
S+L+E + + + LE +++ Q
Sbjct: 1802 QSQLDEAQRALAQRDQELEALQQEQQQ 1828
Score = 33.5 bits (73), Expect = 0.78
Identities = 40/171 (23%), Positives = 68/171 (39%), Gaps = 16/171 (9%)
Frame = +1
Query: 187 EEVRELQK-KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 363
E RE Q+ L + DL +L+ + + + E T E+ +++V+ E +
Sbjct: 1580 EGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQI 1639
Query: 364 EKSEERSGTAQQKLLEAQQS-----------ADENNRMCKVLENRAQQDE----ERMDQL 498
E+ + + Q L Q D+ R K+LE +Q + ER +L
Sbjct: 1640 EELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGREL 1699
Query: 499 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE 651
T Q + + AE+ G S L ++ L E V+ I EL+E
Sbjct: 1700 TTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQE 1750
Score = 33.1 bits (72), Expect = 1.0
Identities = 28/135 (20%), Positives = 62/135 (45%), Gaps = 7/135 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMK--LEKDNAMDKADTCEQQARDANLRAEK-----VNEEVRELQ 207
QQ A D + Q + LEK A + Q+ ++ L E+ +++ VRELQ
Sbjct: 2041 QQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGLEREEEEIRGLHQSVRELQ 2100
Query: 208 KKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 387
LAQ E++++ + ++ N + + + E + L+ +++ +LE+ +
Sbjct: 2101 LTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALR 2160
Query: 388 TAQQKLLEAQQSADE 432
+ + +E ++ A +
Sbjct: 2161 QTEAREIEWREKAQD 2175
>AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein.
Length = 1116
Score = 54.0 bits (124), Expect = 5e-07
Identities = 53/226 (23%), Positives = 110/226 (48%), Gaps = 12/226 (5%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL-----QKKLAQVEEDLIL 243
+KK + +K+E + KA +AR + ++++ RE+ + AQ E D +L
Sbjct: 705 QKKEECLKMESQ--LKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLL 762
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
L++ + +K+K++ E +V N+KV ++ + +++S Q L EA++
Sbjct: 763 EI--LKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSA---QMLEEARRR 817
Query: 424 ADENNRMCKVLENRAQQDEERMDQLTNQLKEA-RLLAEDADGKSDEVSRKLAFVE--DEL 594
D N + L++ ++ ++R+++L L+E+ ++ AE + E S + + +EL
Sbjct: 818 EDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEEL 877
Query: 595 EVAEDRVK----SGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+A ++VK S AK+S ++ L L +L K + V
Sbjct: 878 LMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEV 923
Score = 50.4 bits (115), Expect = 6e-06
Identities = 47/225 (20%), Positives = 102/225 (45%), Gaps = 3/225 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+Q+AA + ++ EK+ ++K +Q +D E+ +L+ L E
Sbjct: 514 EQRAAILQTEVDALRLRLEEKETMLNKKT---KQIQDMAEEKGTQAGEIHDLKDMLDVKE 570
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
+ + + K+E + L +KEKQ+ ++L +V+ ++ D ++ T ++ L
Sbjct: 571 RKVNVLQKKIENLQEQLRDKEKQM-------SSLKERVKSLQADTTNTDTALTTLEEALA 623
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
E +++ + ++ E R + + E+ +++ N K+ + L E ++S K A + D
Sbjct: 624 EKERTIE------RLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLD 677
Query: 589 ELEVAEDRVKSG---DAKISELEEELKVVGNSLKSLEVSEEKANQ 714
E A SG D+++ LE L+ +E +KA++
Sbjct: 678 LKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHE 722
Score = 44.4 bits (100), Expect = 4e-04
Identities = 25/162 (15%), Positives = 76/162 (46%)
Frame = +1
Query: 175 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 354
E + ++ +++ L +EE++ + K+ + ++ EE+ KQ+ + + KV+Q++
Sbjct: 385 EMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLK 444
Query: 355 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 534
E+L E + ++K Q + + + + +++ LTNQ +++ E
Sbjct: 445 EELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIE 504
Query: 535 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 660
++ A ++ E++ R++ + +++ ++++
Sbjct: 505 VLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQ 546
Score = 38.7 bits (86), Expect = 0.021
Identities = 31/170 (18%), Positives = 77/170 (45%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
Q +A R + +N+ ++LQ L + ++ + + L ++ + E+E L E+
Sbjct: 809 QMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESART 868
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
++V+++ +EK ++ + + KL QQS E L ++ E + ++
Sbjct: 869 NAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQ 928
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 654
+ A + +DA+ E+S ++E+ + + D + +L+++
Sbjct: 929 EALLAAISEKDANIALLELSSSKKKTQEEVAALK---REKDRLVQQLKQQ 975
>AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein.
Length = 1088
Score = 54.0 bits (124), Expect = 5e-07
Identities = 53/226 (23%), Positives = 110/226 (48%), Gaps = 12/226 (5%)
Frame = +1
Query: 79 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL-----QKKLAQVEEDLIL 243
+KK + +K+E + KA +AR + ++++ RE+ + AQ E D +L
Sbjct: 677 QKKEECLKMESQ--LKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLL 734
Query: 244 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 423
L++ + +K+K++ E +V N+KV ++ + +++S Q L EA++
Sbjct: 735 EI--LKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSA---QMLEEARRR 789
Query: 424 ADENNRMCKVLENRAQQDEERMDQLTNQLKEA-RLLAEDADGKSDEVSRKLAFVE--DEL 594
D N + L++ ++ ++R+++L L+E+ ++ AE + E S + + +EL
Sbjct: 790 EDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEEL 849
Query: 595 EVAEDRVK----SGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+A ++VK S AK+S ++ L L +L K + V
Sbjct: 850 LMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEV 895
Score = 50.4 bits (115), Expect = 6e-06
Identities = 47/225 (20%), Positives = 102/225 (45%), Gaps = 3/225 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
+Q+AA + ++ EK+ ++K +Q +D E+ +L+ L E
Sbjct: 486 EQRAAILQTEVDALRLRLEEKETMLNKKT---KQIQDMAEEKGTQAGEIHDLKDMLDVKE 542
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 408
+ + + K+E + L +KEKQ+ ++L +V+ ++ D ++ T ++ L
Sbjct: 543 RKVNVLQKKIENLQEQLRDKEKQM-------SSLKERVKSLQADTTNTDTALTTLEEALA 595
Query: 409 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 588
E +++ + ++ E R + + E+ +++ N K+ + L E ++S K A + D
Sbjct: 596 EKERTIE------RLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLD 649
Query: 589 ELEVAEDRVKSG---DAKISELEEELKVVGNSLKSLEVSEEKANQ 714
E A SG D+++ LE L+ +E +KA++
Sbjct: 650 LKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHE 694
Score = 46.8 bits (106), Expect = 8e-05
Identities = 31/190 (16%), Positives = 89/190 (46%), Gaps = 7/190 (3%)
Frame = +1
Query: 175 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 354
E + ++ +++ L +EE++ + K+ + ++ EE+ KQ+ + + K+ Q++
Sbjct: 385 EMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVK 444
Query: 355 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 534
++L + + Q KL ++ + +VL+ E+R L ++ RL E
Sbjct: 445 QELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLE 504
Query: 535 DADGKSDEVSRKLAFVED-------ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 693
+ + ++ ++++ + + E+ +D + + K++ L+++++ + L+ E
Sbjct: 505 EKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEK 564
Query: 694 SEEKANQRVE 723
+RV+
Sbjct: 565 QMSSLKERVK 574
Score = 38.7 bits (86), Expect = 0.021
Identities = 31/170 (18%), Positives = 77/170 (45%)
Frame = +1
Query: 145 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 324
Q +A R + +N+ ++LQ L + ++ + + L ++ + E+E L E+
Sbjct: 781 QMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESART 840
Query: 325 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 504
++V+++ +EK ++ + + KL QQS E L ++ E + ++
Sbjct: 841 NAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQ 900
Query: 505 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 654
+ A + +DA+ E+S ++E+ + + D + +L+++
Sbjct: 901 EALLAAISEKDANIALLELSSSKKKTQEEVAALK---REKDRLVQQLKQQ 947
>AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein.
Length = 1428
Score = 54.0 bits (124), Expect = 5e-07
Identities = 46/184 (25%), Positives = 87/184 (47%), Gaps = 4/184 (2%)
Frame = +1
Query: 184 NEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQL-TATEAEVAALNRKV---QQI 351
NEE +E+QKKL +EE L N++ QA ++LE+K K + T E L ++ + +
Sbjct: 479 NEESQEIQKKLYTLEEHL---SNEM-QAKEELEQKCKSVNTRLEKTAKELEEEITLRKSV 534
Query: 352 EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 531
E L + E Q K E Q+ AD + LEN +++++ L + + +++
Sbjct: 535 ESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQNSQIST 594
Query: 532 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 711
E + ++ A + E + A R++ A+ S+ ++L+ L+ E A
Sbjct: 595 EKVNQLQRQLDETNALLRTESDTAA-RLRKTQAESSKQIQQLESNNRDLQDKNCLLETAK 653
Query: 712 QRVE 723
++E
Sbjct: 654 LKLE 657
Score = 43.6 bits (98), Expect = 7e-04
Identities = 53/242 (21%), Positives = 111/242 (45%), Gaps = 17/242 (7%)
Frame = +1
Query: 49 QQKAATMDAIKKKM---QAMKLEKDNAMDKAD------TCE----QQARDANLRAEKV-N 186
+ K+ M ++KK+ + +K + +N + +A+ C+ QQ + L+ + V N
Sbjct: 767 EAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLN 826
Query: 187 EEVRELQKKLAQVEEDLILNKNKLE---QANKDLEEKEKQLTATEAEVAALNRKVQQIEE 357
E+VR L K+ Q + L +N L+ Q L+ EKQL + + +++
Sbjct: 827 EDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNA 886
Query: 358 DLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 537
+L K E + Q K L+ Q A++ + + + ++ +E ++ T KE + ++
Sbjct: 887 ELRK-ERQDADGQMKELQDQLEAEQ--YFSTLYKTQVRELKEECEEKTKLGKELQQKKQE 943
Query: 538 ADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 717
+ D ++ +L + + + + + S+LE+E K+ +K LE+ E A +
Sbjct: 944 LQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKE-KI----MKELEIKEMMARHK 998
Query: 718 VE 723
E
Sbjct: 999 QE 1000
Score = 38.7 bits (86), Expect = 0.021
Identities = 47/216 (21%), Positives = 90/216 (41%), Gaps = 9/216 (4%)
Frame = +1
Query: 85 KMQAMKLEKDNAMDKADTCEQQARDANLRA--EKVNEEVRELQKKLA------QVEEDLI 240
K+ LE++ A KA ++ + E +E ++E++KKL Q E+L+
Sbjct: 735 KVIQQSLEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLL 794
Query: 241 LNKNK-LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 417
L K + DL++ ++++ + LN V+ + +E+ ++ Q L
Sbjct: 795 LEAEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQT 854
Query: 418 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 597
Q + K L+ E L Q E R +DADG+ E ++D+LE
Sbjct: 855 QQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKE-------LQDQLE 907
Query: 598 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 705
+ ++ EL+EE + K L+ +++
Sbjct: 908 AEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQE 943
>DQ139275-1|ABA43896.1| 1313|Homo sapiens Tax1-binding protein 2
protein.
Length = 1313
Score = 53.6 bits (123), Expect = 7e-07
Identities = 53/223 (23%), Positives = 105/223 (47%), Gaps = 10/223 (4%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 261
+++++ + E+D + +Q + + R+LQK +A+ EE +L
Sbjct: 819 QELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLS 878
Query: 262 --QANKDLEEK-----EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
QA L+E+ E++ AT +VA L R +Q E +L S+E+ ++ K E +
Sbjct: 879 GVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEK--ISKMKANETKL 936
Query: 421 SADENNRMCKVL---ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 591
D+ R+ +VL E+R + E + L +L+ +RL G SD ++ A ++D
Sbjct: 937 EGDK-RRLKEVLDASESRTVKLELQRRSLEGELQRSRL------GLSDREAQAQA-LQDR 988
Query: 592 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
++ + +V + K L+ ++ + +L +E SE +V
Sbjct: 989 VDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKV 1031
Score = 43.2 bits (97), Expect = 0.001
Identities = 42/229 (18%), Positives = 106/229 (46%), Gaps = 4/229 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNA---MDKADTCEQQARDA-NLRAEKVNEEVRELQKKL 216
+Q+A +++++ ++LE++ A ++ + +QA++A + + E +LQ++L
Sbjct: 80 EQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQL 139
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 396
AQ+ L + +LEQA ++ + + + L E AL ++ + L +E T
Sbjct: 140 AQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLS 199
Query: 397 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLA 576
++ + + ++ + Q E R +QL + + L E G+ + +++
Sbjct: 200 EEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQII 259
Query: 577 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+++ + ++ + K+ + E E + SL+ + E+ QR++
Sbjct: 260 ATQEKASLDKELMAQ---KLVQAEREAQA---SLREQRAAHEEDLQRLQ 302
Score = 40.7 bits (91), Expect = 0.005
Identities = 43/157 (27%), Positives = 68/157 (43%), Gaps = 11/157 (7%)
Frame = +1
Query: 166 LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAA----LN 333
L+AEK EV E K +L L+ KL L++ +L+A +A LN
Sbjct: 2 LQAEKA--EVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLN 59
Query: 334 RKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD-------ENNRMCKVLENRAQQDEERMD 492
R V Q+EE+ + R A+Q+ A++ + E + LE + E+ +
Sbjct: 60 RLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQE 119
Query: 493 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 603
L QL R + ++SR+L+ E ELE A
Sbjct: 120 ALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQA 156
Score = 37.1 bits (82), Expect = 0.064
Identities = 48/238 (20%), Positives = 100/238 (42%), Gaps = 14/238 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
Q + + A ++K+ MK + ++ + R K+ + R L+ +L +
Sbjct: 913 QATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSR 972
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK-- 402
L + + + ++ ++Q+ +E + L V+++ L K EE G + K
Sbjct: 973 LGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVR 1032
Query: 403 -LLEA--QQSA------DENNRMCKVL---ENRAQQDEERMDQLTNQLKEARLLAEDADG 546
L EA Q SA D+N + K L E+ Q +ER+D L EAR +
Sbjct: 1033 GLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGE 1092
Query: 547 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ + ++A +E + AE +++ + + +E N+++ L+ +R+
Sbjct: 1093 QVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERL 1150
Score = 36.3 bits (80), Expect = 0.11
Identities = 44/217 (20%), Positives = 97/217 (44%), Gaps = 1/217 (0%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
+++ + ++++ A + + + A++ + NEE+R KK E + I
Sbjct: 487 LRESQEGREVQRQEAGELRRSLGEGAKEREA-LRRSNEELRSAVKK---AESERI----S 538
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
L+ AN+D KE++L E A+ ++ ++ L++ E + LEA++ E
Sbjct: 539 LKLANED---KEQKLALLEEARTAVGKEAGELRTGLQEVE-------RSRLEARRELQEL 588
Query: 436 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 615
R K+L++ + + +L +L +++ ++ + ++L E LEV +
Sbjct: 589 RRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQEL 648
Query: 616 KSGDAKISELEEELKV-VGNSLKSLEVSEEKANQRVE 723
+ K+ E E E + L SLE + Q+++
Sbjct: 649 QVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLD 685
Score = 35.9 bits (79), Expect = 0.15
Identities = 39/176 (22%), Positives = 78/176 (44%), Gaps = 1/176 (0%)
Frame = +1
Query: 136 TCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 315
T E+ + D L A+K+ + RE Q A + E ++ L++ ++ E ++L EA
Sbjct: 261 TQEKASLDKELMAQKLVQAEREAQ---ASLREQRAAHEEDLQRLQREKEAAWREL---EA 314
Query: 316 EVAALNRKVQQIEED-LEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD 492
E A L ++Q+ +E+ L + E +++ QQ DE + + E+
Sbjct: 315 ERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLA---------ESEKQQ 365
Query: 493 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 660
L+ + E L+E G ++ +E + A+ R + + ++ L EL+
Sbjct: 366 ALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELR 421
Score = 33.5 bits (73), Expect = 0.78
Identities = 31/128 (24%), Positives = 61/128 (47%), Gaps = 10/128 (7%)
Frame = +1
Query: 181 VNEEVRELQKKLAQVEED--------LILNKNKLEQANKDLEEKEKQLTATEAEVAALNR 336
+ E + LQ+ LAQ+E + L L K+++ + L++ E++ + + L+
Sbjct: 1146 LQERLGSLQRALAQLEAEKREVERSALRLEKDRV-ALRRTLDKVEREKLRSHEDTVRLSA 1204
Query: 337 KVQQIEEDLEKSEERSGTAQQKL--LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL 510
+ +++ L +E AQ+++ LEAQ E + LE AQQ + + Q +L
Sbjct: 1205 EKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERL 1264
Query: 511 KEARLLAE 534
+ A+ E
Sbjct: 1265 RSAQAQTE 1272
>BX284668-3|CAH70057.1| 1898|Homo sapiens ciliary rootlet coiled-coil,
rootletin protein.
Length = 1898
Score = 53.6 bits (123), Expect = 7e-07
Identities = 53/223 (23%), Positives = 105/223 (47%), Gaps = 10/223 (4%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 261
+++++ + E+D + +Q + + R+LQK +A+ EE +L
Sbjct: 1397 QELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLS 1456
Query: 262 --QANKDLEEK-----EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
QA L+E+ E++ AT +VA L R +Q E +L S+E+ ++ K E +
Sbjct: 1457 GVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEK--ISKMKANETKL 1514
Query: 421 SADENNRMCKVL---ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 591
D+ R+ +VL E+R + E + L +L+ +RL G SD ++ A ++D
Sbjct: 1515 EGDK-RRLKEVLDASESRTVKLELQRRSLEGELQRSRL------GLSDREAQAQA-LQDR 1566
Query: 592 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
++ + +V + K L+ ++ + +L +E SE +V
Sbjct: 1567 VDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKV 1609
Score = 49.6 bits (113), Expect = 1e-05
Identities = 41/216 (18%), Positives = 91/216 (42%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++ + + EK N +QQA + EK+ EL+++ ++EE+
Sbjct: 475 LRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQD 534
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
+ ++LE +QL E + + L +++ ++ E L ++ + Q + E ++ +
Sbjct: 535 GARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKA 594
Query: 436 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 615
LE + L + L + L E +++R +A +E+E + R
Sbjct: 595 EAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQ 654
Query: 616 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ + + + EE + L+ L + +E A Q +E
Sbjct: 655 RQAEQEATVAREEQE----RLEELRLEQEVARQGLE 686
Score = 43.2 bits (97), Expect = 0.001
Identities = 42/229 (18%), Positives = 106/229 (46%), Gaps = 4/229 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNA---MDKADTCEQQARDA-NLRAEKVNEEVRELQKKL 216
+Q+A +++++ ++LE++ A ++ + +QA++A + + E +LQ++L
Sbjct: 658 EQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQL 717
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 396
AQ+ L + +LEQA ++ + + + L E AL ++ + L +E T
Sbjct: 718 AQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLS 777
Query: 397 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLA 576
++ + + ++ + Q E R +QL + + L E G+ + +++
Sbjct: 778 EEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQII 837
Query: 577 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+++ + ++ + K+ + E E + SL+ + E+ QR++
Sbjct: 838 ATQEKASLDKELMAQ---KLVQAEREAQA---SLREQRAAHEEDLQRLQ 880
Score = 37.1 bits (82), Expect = 0.064
Identities = 48/238 (20%), Positives = 100/238 (42%), Gaps = 14/238 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
Q + + A ++K+ MK + ++ + R K+ + R L+ +L +
Sbjct: 1491 QATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSR 1550
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK-- 402
L + + + ++ ++Q+ +E + L V+++ L K EE G + K
Sbjct: 1551 LGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVR 1610
Query: 403 -LLEA--QQSA------DENNRMCKVL---ENRAQQDEERMDQLTNQLKEARLLAEDADG 546
L EA Q SA D+N + K L E+ Q +ER+D L EAR +
Sbjct: 1611 GLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGE 1670
Query: 547 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ + ++A +E + AE +++ + + +E N+++ L+ +R+
Sbjct: 1671 QVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERL 1728
Score = 36.3 bits (80), Expect = 0.11
Identities = 44/217 (20%), Positives = 97/217 (44%), Gaps = 1/217 (0%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
+++ + ++++ A + + + A++ + NEE+R KK E + I
Sbjct: 1065 LRESQEGREVQRQEAGELRRSLGEGAKEREA-LRRSNEELRSAVKK---AESERI----S 1116
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
L+ AN+D KE++L E A+ ++ ++ L++ E + LEA++ E
Sbjct: 1117 LKLANED---KEQKLALLEEARTAVGKEAGELRTGLQEVE-------RSRLEARRELQEL 1166
Query: 436 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 615
R K+L++ + + +L +L +++ ++ + ++L E LEV +
Sbjct: 1167 RRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQEL 1226
Query: 616 KSGDAKISELEEELKV-VGNSLKSLEVSEEKANQRVE 723
+ K+ E E E + L SLE + Q+++
Sbjct: 1227 QVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLD 1263
Score = 35.9 bits (79), Expect = 0.15
Identities = 39/176 (22%), Positives = 78/176 (44%), Gaps = 1/176 (0%)
Frame = +1
Query: 136 TCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 315
T E+ + D L A+K+ + RE Q A + E ++ L++ ++ E ++L EA
Sbjct: 839 TQEKASLDKELMAQKLVQAEREAQ---ASLREQRAAHEEDLQRLQREKEAAWREL---EA 892
Query: 316 EVAALNRKVQQIEED-LEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD 492
E A L ++Q+ +E+ L + E +++ QQ DE + + E+
Sbjct: 893 ERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLA---------ESEKQQ 943
Query: 493 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 660
L+ + E L+E G ++ +E + A+ R + + ++ L EL+
Sbjct: 944 ALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELR 999
Score = 33.5 bits (73), Expect = 0.78
Identities = 31/128 (24%), Positives = 61/128 (47%), Gaps = 10/128 (7%)
Frame = +1
Query: 181 VNEEVRELQKKLAQVEED--------LILNKNKLEQANKDLEEKEKQLTATEAEVAALNR 336
+ E + LQ+ LAQ+E + L L K+++ + L++ E++ + + L+
Sbjct: 1724 LQERLGSLQRALAQLEAEKREVERSALRLEKDRV-ALRRTLDKVEREKLRSHEDTVRLSA 1782
Query: 337 KVQQIEEDLEKSEERSGTAQQKL--LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL 510
+ +++ L +E AQ+++ LEAQ E + LE AQQ + + Q +L
Sbjct: 1783 EKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERL 1842
Query: 511 KEARLLAE 534
+ A+ E
Sbjct: 1843 RSAQAQTE 1850
Score = 31.1 bits (67), Expect = 4.2
Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 3/96 (3%)
Frame = +1
Query: 154 RDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL--EQANKDLEEKEKQLTATEAEVAA 327
R A RAE E+ LQ +L + D +L + L +Q DL++ + TE +A
Sbjct: 228 RLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVTELGLAV 287
Query: 328 LNRKVQQIEED-LEKSEERSGTAQQKLLEAQQSADE 432
+ Q +E+D + K A + L +Q+A E
Sbjct: 288 KRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALE 323
>BX284668-2|CAH70055.1| 2017|Homo sapiens ciliary rootlet coiled-coil,
rootletin protein.
Length = 2017
Score = 53.6 bits (123), Expect = 7e-07
Identities = 53/223 (23%), Positives = 105/223 (47%), Gaps = 10/223 (4%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 261
+++++ + E+D + +Q + + R+LQK +A+ EE +L
Sbjct: 1516 QELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLS 1575
Query: 262 --QANKDLEEK-----EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
QA L+E+ E++ AT +VA L R +Q E +L S+E+ ++ K E +
Sbjct: 1576 GVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEK--ISKMKANETKL 1633
Query: 421 SADENNRMCKVL---ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 591
D+ R+ +VL E+R + E + L +L+ +RL G SD ++ A ++D
Sbjct: 1634 EGDK-RRLKEVLDASESRTVKLELQRRSLEGELQRSRL------GLSDREAQAQA-LQDR 1685
Query: 592 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
++ + +V + K L+ ++ + +L +E SE +V
Sbjct: 1686 VDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKV 1728
Score = 49.6 bits (113), Expect = 1e-05
Identities = 41/216 (18%), Positives = 91/216 (42%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++ + + EK N +QQA + EK+ EL+++ ++EE+
Sbjct: 594 LRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQD 653
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
+ ++LE +QL E + + L +++ ++ E L ++ + Q + E ++ +
Sbjct: 654 GARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKA 713
Query: 436 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 615
LE + L + L + L E +++R +A +E+E + R
Sbjct: 714 EAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQ 773
Query: 616 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ + + + EE + L+ L + +E A Q +E
Sbjct: 774 RQAEQEATVAREEQE----RLEELRLEQEVARQGLE 805
Score = 43.2 bits (97), Expect = 0.001
Identities = 42/229 (18%), Positives = 106/229 (46%), Gaps = 4/229 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNA---MDKADTCEQQARDA-NLRAEKVNEEVRELQKKL 216
+Q+A +++++ ++LE++ A ++ + +QA++A + + E +LQ++L
Sbjct: 777 EQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQL 836
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 396
AQ+ L + +LEQA ++ + + + L E AL ++ + L +E T
Sbjct: 837 AQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLS 896
Query: 397 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLA 576
++ + + ++ + Q E R +QL + + L E G+ + +++
Sbjct: 897 EEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQII 956
Query: 577 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+++ + ++ + K+ + E E + SL+ + E+ QR++
Sbjct: 957 ATQEKASLDKELMAQ---KLVQAEREAQA---SLREQRAAHEEDLQRLQ 999
Score = 37.1 bits (82), Expect = 0.064
Identities = 48/238 (20%), Positives = 100/238 (42%), Gaps = 14/238 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
Q + + A ++K+ MK + ++ + R K+ + R L+ +L +
Sbjct: 1610 QATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSR 1669
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK-- 402
L + + + ++ ++Q+ +E + L V+++ L K EE G + K
Sbjct: 1670 LGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVR 1729
Query: 403 -LLEA--QQSA------DENNRMCKVL---ENRAQQDEERMDQLTNQLKEARLLAEDADG 546
L EA Q SA D+N + K L E+ Q +ER+D L EAR +
Sbjct: 1730 GLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGE 1789
Query: 547 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ + ++A +E + AE +++ + + +E N+++ L+ +R+
Sbjct: 1790 QVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERL 1847
Score = 36.3 bits (80), Expect = 0.11
Identities = 44/217 (20%), Positives = 97/217 (44%), Gaps = 1/217 (0%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
+++ + ++++ A + + + A++ + NEE+R KK E + I
Sbjct: 1184 LRESQEGREVQRQEAGELRRSLGEGAKEREA-LRRSNEELRSAVKK---AESERI----S 1235
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
L+ AN+D KE++L E A+ ++ ++ L++ E + LEA++ E
Sbjct: 1236 LKLANED---KEQKLALLEEARTAVGKEAGELRTGLQEVE-------RSRLEARRELQEL 1285
Query: 436 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 615
R K+L++ + + +L +L +++ ++ + ++L E LEV +
Sbjct: 1286 RRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQEL 1345
Query: 616 KSGDAKISELEEELKV-VGNSLKSLEVSEEKANQRVE 723
+ K+ E E E + L SLE + Q+++
Sbjct: 1346 QVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLD 1382
Score = 35.9 bits (79), Expect = 0.15
Identities = 39/176 (22%), Positives = 78/176 (44%), Gaps = 1/176 (0%)
Frame = +1
Query: 136 TCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 315
T E+ + D L A+K+ + RE Q A + E ++ L++ ++ E ++L EA
Sbjct: 958 TQEKASLDKELMAQKLVQAEREAQ---ASLREQRAAHEEDLQRLQREKEAAWREL---EA 1011
Query: 316 EVAALNRKVQQIEED-LEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD 492
E A L ++Q+ +E+ L + E +++ QQ DE + + E+
Sbjct: 1012 ERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLA---------ESEKQQ 1062
Query: 493 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 660
L+ + E L+E G ++ +E + A+ R + + ++ L EL+
Sbjct: 1063 ALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELR 1118
Score = 33.5 bits (73), Expect = 0.78
Identities = 31/128 (24%), Positives = 61/128 (47%), Gaps = 10/128 (7%)
Frame = +1
Query: 181 VNEEVRELQKKLAQVEED--------LILNKNKLEQANKDLEEKEKQLTATEAEVAALNR 336
+ E + LQ+ LAQ+E + L L K+++ + L++ E++ + + L+
Sbjct: 1843 LQERLGSLQRALAQLEAEKREVERSALRLEKDRV-ALRRTLDKVEREKLRSHEDTVRLSA 1901
Query: 337 KVQQIEEDLEKSEERSGTAQQKL--LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL 510
+ +++ L +E AQ+++ LEAQ E + LE AQQ + + Q +L
Sbjct: 1902 EKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERL 1961
Query: 511 KEARLLAE 534
+ A+ E
Sbjct: 1962 RSAQAQTE 1969
Score = 31.1 bits (67), Expect = 4.2
Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 3/96 (3%)
Frame = +1
Query: 154 RDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL--EQANKDLEEKEKQLTATEAEVAA 327
R A RAE E+ LQ +L + D +L + L +Q DL++ + TE +A
Sbjct: 347 RLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVTELGLAV 406
Query: 328 LNRKVQQIEED-LEKSEERSGTAQQKLLEAQQSADE 432
+ Q +E+D + K A + L +Q+A E
Sbjct: 407 KRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALE 442
>AL049569-4|CAI20365.1| 1898|Homo sapiens ciliary rootlet coiled-coil,
rootletin protein.
Length = 1898
Score = 53.6 bits (123), Expect = 7e-07
Identities = 53/223 (23%), Positives = 105/223 (47%), Gaps = 10/223 (4%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 261
+++++ + E+D + +Q + + R+LQK +A+ EE +L
Sbjct: 1397 QELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLS 1456
Query: 262 --QANKDLEEK-----EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
QA L+E+ E++ AT +VA L R +Q E +L S+E+ ++ K E +
Sbjct: 1457 GVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEK--ISKMKANETKL 1514
Query: 421 SADENNRMCKVL---ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 591
D+ R+ +VL E+R + E + L +L+ +RL G SD ++ A ++D
Sbjct: 1515 EGDK-RRLKEVLDASESRTVKLELQRRSLEGELQRSRL------GLSDREAQAQA-LQDR 1566
Query: 592 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
++ + +V + K L+ ++ + +L +E SE +V
Sbjct: 1567 VDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKV 1609
Score = 49.6 bits (113), Expect = 1e-05
Identities = 41/216 (18%), Positives = 91/216 (42%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++ + + EK N +QQA + EK+ EL+++ ++EE+
Sbjct: 475 LRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQD 534
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
+ ++LE +QL E + + L +++ ++ E L ++ + Q + E ++ +
Sbjct: 535 GARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKA 594
Query: 436 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 615
LE + L + L + L E +++R +A +E+E + R
Sbjct: 595 EAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQ 654
Query: 616 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ + + + EE + L+ L + +E A Q +E
Sbjct: 655 RQAEQEATVAREEQE----RLEELRLEQEVARQGLE 686
Score = 43.2 bits (97), Expect = 0.001
Identities = 42/229 (18%), Positives = 106/229 (46%), Gaps = 4/229 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNA---MDKADTCEQQARDA-NLRAEKVNEEVRELQKKL 216
+Q+A +++++ ++LE++ A ++ + +QA++A + + E +LQ++L
Sbjct: 658 EQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQL 717
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 396
AQ+ L + +LEQA ++ + + + L E AL ++ + L +E T
Sbjct: 718 AQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLS 777
Query: 397 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLA 576
++ + + ++ + Q E R +QL + + L E G+ + +++
Sbjct: 778 EEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQII 837
Query: 577 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+++ + ++ + K+ + E E + SL+ + E+ QR++
Sbjct: 838 ATQEKASLDKELMAQ---KLVQAEREAQA---SLREQRAAHEEDLQRLQ 880
Score = 37.1 bits (82), Expect = 0.064
Identities = 48/238 (20%), Positives = 100/238 (42%), Gaps = 14/238 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
Q + + A ++K+ MK + ++ + R K+ + R L+ +L +
Sbjct: 1491 QATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSR 1550
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK-- 402
L + + + ++ ++Q+ +E + L V+++ L K EE G + K
Sbjct: 1551 LGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVR 1610
Query: 403 -LLEA--QQSA------DENNRMCKVL---ENRAQQDEERMDQLTNQLKEARLLAEDADG 546
L EA Q SA D+N + K L E+ Q +ER+D L EAR +
Sbjct: 1611 GLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGE 1670
Query: 547 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ + ++A +E + AE +++ + + +E N+++ L+ +R+
Sbjct: 1671 QVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERL 1728
Score = 36.3 bits (80), Expect = 0.11
Identities = 44/217 (20%), Positives = 97/217 (44%), Gaps = 1/217 (0%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
+++ + ++++ A + + + A++ + NEE+R KK E + I
Sbjct: 1065 LRESQEGREVQRQEAGELRRSLGEGAKEREA-LRRSNEELRSAVKK---AESERI----S 1116
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
L+ AN+D KE++L E A+ ++ ++ L++ E + LEA++ E
Sbjct: 1117 LKLANED---KEQKLALLEEARTAVGKEAGELRTGLQEVE-------RSRLEARRELQEL 1166
Query: 436 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 615
R K+L++ + + +L +L +++ ++ + ++L E LEV +
Sbjct: 1167 RRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQEL 1226
Query: 616 KSGDAKISELEEELKV-VGNSLKSLEVSEEKANQRVE 723
+ K+ E E E + L SLE + Q+++
Sbjct: 1227 QVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLD 1263
Score = 35.9 bits (79), Expect = 0.15
Identities = 39/176 (22%), Positives = 78/176 (44%), Gaps = 1/176 (0%)
Frame = +1
Query: 136 TCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 315
T E+ + D L A+K+ + RE Q A + E ++ L++ ++ E ++L EA
Sbjct: 839 TQEKASLDKELMAQKLVQAEREAQ---ASLREQRAAHEEDLQRLQREKEAAWREL---EA 892
Query: 316 EVAALNRKVQQIEED-LEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD 492
E A L ++Q+ +E+ L + E +++ QQ DE + + E+
Sbjct: 893 ERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLA---------ESEKQQ 943
Query: 493 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 660
L+ + E L+E G ++ +E + A+ R + + ++ L EL+
Sbjct: 944 ALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELR 999
Score = 33.5 bits (73), Expect = 0.78
Identities = 31/128 (24%), Positives = 61/128 (47%), Gaps = 10/128 (7%)
Frame = +1
Query: 181 VNEEVRELQKKLAQVEED--------LILNKNKLEQANKDLEEKEKQLTATEAEVAALNR 336
+ E + LQ+ LAQ+E + L L K+++ + L++ E++ + + L+
Sbjct: 1724 LQERLGSLQRALAQLEAEKREVERSALRLEKDRV-ALRRTLDKVEREKLRSHEDTVRLSA 1782
Query: 337 KVQQIEEDLEKSEERSGTAQQKL--LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL 510
+ +++ L +E AQ+++ LEAQ E + LE AQQ + + Q +L
Sbjct: 1783 EKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERL 1842
Query: 511 KEARLLAE 534
+ A+ E
Sbjct: 1843 RSAQAQTE 1850
Score = 31.1 bits (67), Expect = 4.2
Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 3/96 (3%)
Frame = +1
Query: 154 RDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL--EQANKDLEEKEKQLTATEAEVAA 327
R A RAE E+ LQ +L + D +L + L +Q DL++ + TE +A
Sbjct: 228 RLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVTELGLAV 287
Query: 328 LNRKVQQIEED-LEKSEERSGTAQQKLLEAQQSADE 432
+ Q +E+D + K A + L +Q+A E
Sbjct: 288 KRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALE 323
>AL049569-3|CAI20363.1| 2017|Homo sapiens ciliary rootlet coiled-coil,
rootletin protein.
Length = 2017
Score = 53.6 bits (123), Expect = 7e-07
Identities = 53/223 (23%), Positives = 105/223 (47%), Gaps = 10/223 (4%)
Frame = +1
Query: 82 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 261
+++++ + E+D + +Q + + R+LQK +A+ EE +L
Sbjct: 1516 QELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLS 1575
Query: 262 --QANKDLEEK-----EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 420
QA L+E+ E++ AT +VA L R +Q E +L S+E+ ++ K E +
Sbjct: 1576 GVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEK--ISKMKANETKL 1633
Query: 421 SADENNRMCKVL---ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 591
D+ R+ +VL E+R + E + L +L+ +RL G SD ++ A ++D
Sbjct: 1634 EGDK-RRLKEVLDASESRTVKLELQRRSLEGELQRSRL------GLSDREAQAQA-LQDR 1685
Query: 592 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
++ + +V + K L+ ++ + +L +E SE +V
Sbjct: 1686 VDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKV 1728
Score = 49.6 bits (113), Expect = 1e-05
Identities = 41/216 (18%), Positives = 91/216 (42%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
++ + + EK N +QQA + EK+ EL+++ ++EE+
Sbjct: 594 LRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQD 653
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
+ ++LE +QL E + + L +++ ++ E L ++ + Q + E ++ +
Sbjct: 654 GARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKA 713
Query: 436 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 615
LE + L + L + L E +++R +A +E+E + R
Sbjct: 714 EAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQ 773
Query: 616 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+ + + + EE + L+ L + +E A Q +E
Sbjct: 774 RQAEQEATVAREEQE----RLEELRLEQEVARQGLE 805
Score = 43.2 bits (97), Expect = 0.001
Identities = 42/229 (18%), Positives = 106/229 (46%), Gaps = 4/229 (1%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNA---MDKADTCEQQARDA-NLRAEKVNEEVRELQKKL 216
+Q+A +++++ ++LE++ A ++ + +QA++A + + E +LQ++L
Sbjct: 777 EQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQL 836
Query: 217 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 396
AQ+ L + +LEQA ++ + + + L E AL ++ + L +E T
Sbjct: 837 AQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLS 896
Query: 397 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLA 576
++ + + ++ + Q E R +QL + + L E G+ + +++
Sbjct: 897 EEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQII 956
Query: 577 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 723
+++ + ++ + K+ + E E + SL+ + E+ QR++
Sbjct: 957 ATQEKASLDKELMAQ---KLVQAEREAQA---SLREQRAAHEEDLQRLQ 999
Score = 37.1 bits (82), Expect = 0.064
Identities = 48/238 (20%), Positives = 100/238 (42%), Gaps = 14/238 (5%)
Frame = +1
Query: 49 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 228
Q + + A ++K+ MK + ++ + R K+ + R L+ +L +
Sbjct: 1610 QATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSR 1669
Query: 229 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK-- 402
L + + + ++ ++Q+ +E + L V+++ L K EE G + K
Sbjct: 1670 LGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVR 1729
Query: 403 -LLEA--QQSA------DENNRMCKVL---ENRAQQDEERMDQLTNQLKEARLLAEDADG 546
L EA Q SA D+N + K L E+ Q +ER+D L EAR +
Sbjct: 1730 GLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGE 1789
Query: 547 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 720
+ + ++A +E + AE +++ + + +E N+++ L+ +R+
Sbjct: 1790 QVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERL 1847
Score = 36.3 bits (80), Expect = 0.11
Identities = 44/217 (20%), Positives = 97/217 (44%), Gaps = 1/217 (0%)
Frame = +1
Query: 76 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 255
+++ + ++++ A + + + A++ + NEE+R KK E + I
Sbjct: 1184 LRESQEGREVQRQEAGELRRSLGEGAKEREA-LRRSNEELRSAVKK---AESERI----S 1235
Query: 256 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 435
L+ AN+D KE++L E A+ ++ ++ L++ E + LEA++ E
Sbjct: 1236 LKLANED---KEQKLALLEEARTAVGKEAGELRTGLQEVE-------RSRLEARRELQEL 1285
Query: 436 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 615
R K+L++ + + +L +L +++ ++ + ++L E LEV +
Sbjct: 1286 RRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQEL 1345
Query: 616 KSGDAKISELEEELKV-VGNSLKSLEVSEEKANQRVE 723
+ K+ E E E + L SLE + Q+++
Sbjct: 1346 QVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLD 1382
Score = 35.9 bits (79), Expect = 0.15
Identities = 39/176 (22%), Positives = 78/176 (44%), Gaps = 1/176 (0%)
Frame = +1
Query: 136 TCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 315
T E+ + D L A+K+ + RE Q A + E ++ L++ ++ E ++L EA
Sbjct: 958 TQEKASLDKELMAQKLVQAEREAQ---ASLREQRAAHEEDLQRLQREKEAAWREL---EA 1011
Query: 316 EVAALNRKVQQIEED-LEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD 492
E A L ++Q+ +E+ L + E +++ QQ DE + + E+
Sbjct: 1012 ERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLA---------ESEKQQ 1062
Query: 493 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 660
L+ + E L+E G ++ +E + A+ R + + ++ L EL+
Sbjct: 1063 ALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELR 1118
Score = 33.5 bits (73), Expect = 0.78
Identities = 31/128 (24%), Positives = 61/128 (47%), Gaps = 10/128 (7%)
Frame = +1
Query: 181 VNEEVRELQKKLAQVEED--------LILNKNKLEQANKDLEEKEKQLTATEAEVAALNR 336
+ E + LQ+ LAQ+E + L L K+++ + L++ E++ + + L+
Sbjct: 1843 LQERLGSLQRALAQLEAEKREVERSALRLEKDRV-ALRRTLDKVEREKLRSHEDTVRLSA 1901
Query: 337 KVQQIEEDLEKSEERSGTAQQKL--LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL 510
+ +++ L +E AQ+++ LEAQ E + LE AQQ + + Q +L
Sbjct: 1902 EKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERL 1961
Query: 511 KEARLLAE 534
+ A+ E
Sbjct: 1962 RSAQAQTE 1969
Score = 31.1 bits (67), Expect = 4.2
Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 3/96 (3%)
Frame = +1
Query: 154 RDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL--EQANKDLEEKEKQLTATEAEVAA 327
R A RAE E+ LQ +L + D +L + L +Q DL++ + TE +A
Sbjct: 347 RLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVTELGLAV 406
Query: 328 LNRKVQQIEED-LEKSEERSGTAQQKLLEAQQSADE 432
+ Q +E+D + K A + L +Q+A E
Sbjct: 407 KRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALE 442
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.311 0.125 0.315
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 85,804,339
Number of Sequences: 237096
Number of extensions: 1961765
Number of successful extensions: 18069
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 10957
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 15938
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8511181328
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.2 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (21.8 bits)
- SilkBase 1999-2023 -