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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= epV30915
         (645 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AL513122-4|CAI14414.1|  228|Homo sapiens gelsolin (amyloidosis, ...   218   2e-56
X04412-1|CAA28000.1|  782|Homo sapiens plasma gelsolin protein.       217   3e-56
BC026033-1|AAH26033.1|  782|Homo sapiens gelsolin (amyloidosis, ...   217   3e-56
AL513122-6|CAM20459.1|  731|Homo sapiens gelsolin (amyloidosis, ...   217   3e-56
AL513122-5|CAI14415.1|  260|Homo sapiens gelsolin (amyloidosis, ...   217   3e-56
AL513122-3|CAI14413.1|  782|Homo sapiens gelsolin (amyloidosis, ...   217   3e-56
AF276507-1|AAK60494.1|  715|Homo sapiens scinderin protein.           195   1e-49
AC005281-1|AAD15423.1|  527|Homo sapiens WUGSC:H_DJ0722F20.1 pro...   195   1e-49
AB067492-1|BAB67798.1|  626|Homo sapiens KIAA1905 protein protein.    195   1e-49
BC021090-1|AAH21090.1|  715|Homo sapiens SCIN protein protein.        194   2e-49
AK075123-1|BAC11416.1|  715|Homo sapiens protein ( Homo sapiens ...   194   3e-49
AF041449-1|AAC25051.1|  819|Homo sapiens advillin protein.            187   3e-47
X12901-1|CAA31386.1|  827|Homo sapiens protein ( Human mRNA for ...   175   8e-44
BC017303-1|AAH17303.1|  421|Homo sapiens VIL1 protein protein.        175   8e-44
AK223398-1|BAD97118.1|  827|Homo sapiens villin 1 variant protein.    175   8e-44
BC111730-1|AAI11731.1|  812|Homo sapiens AVIL protein protein.        173   4e-43
M94345-1|AAA59570.1|  348|Homo sapiens macrophage capping protei...   160   4e-39
BC014549-1|AAH14549.1|  348|Homo sapiens capping protein (actin ...   160   4e-39
BC000728-1|AAH00728.1|  348|Homo sapiens capping protein (actin ...   160   4e-39
AC062037-3|AAY24128.1|  348|Homo sapiens unknown protein.             160   4e-39
U12026-1|AAA92670.1|  172|Homo sapiens Cap-G protein.                 133   6e-31
U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein.                  124   2e-28
U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog prot...   124   2e-28
BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog (D...   124   2e-28
AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog va...   124   2e-28
AL513122-7|CAI14416.1|  485|Homo sapiens gelsolin (amyloidosis, ...    92   2e-18
AK075198-1|BAC11465.1|  396|Homo sapiens protein ( Homo sapiens ...    81   3e-15
AK027778-1|BAB55361.1|  468|Homo sapiens protein ( Homo sapiens ...    81   3e-15
BC075797-1|AAH75797.1|   85|Homo sapiens Unknown (protein for MG...    73   1e-12
X07066-1|CAA30102.1|   69|Homo sapiens protein ( Human gene for ...    71   3e-12
D88154-1|BAA21668.1|  686|Homo sapiens villin-like protein protein.    62   2e-09
BC004300-1|AAH04300.1|  672|Homo sapiens VILL protein protein.         62   2e-09
BC000243-1|AAH00243.1|  686|Homo sapiens VILL protein protein.         62   2e-09
AL160060-2|CAH71300.1| 2214|Homo sapiens supervillin protein.          58   2e-08
AL158167-3|CAI15237.1| 2214|Homo sapiens supervillin protein.          58   2e-08
AF109135-1|AAD14682.1| 2214|Homo sapiens archvillin protein.           58   2e-08
AL160060-1|CAH71301.1| 1788|Homo sapiens supervillin protein.          58   2e-08
AL158167-2|CAI15236.1| 1788|Homo sapiens supervillin protein.          58   2e-08
AF051851-1|AAC64696.1| 1788|Homo sapiens supervillin protein.          58   2e-08
AF051850-1|AAC64695.1| 1788|Homo sapiens supervillin protein.          58   2e-08
BC017491-1|AAH17491.1|  285|Homo sapiens Similar to gelsolin (am...    55   2e-07
AK092426-1|BAC03887.1|  258|Homo sapiens protein ( Homo sapiens ...    36   0.16 
BC117319-1|AAI17320.1|  257|Homo sapiens TPRXL protein protein.        33   0.87 
AL513122-9|CAI14417.1|  207|Homo sapiens gelsolin (amyloidosis, ...    32   1.5  
BC106877-1|AAI06878.1|  663|Homo sapiens chromosome 1 open readi...    32   2.0  
AK001763-1|BAA91892.1|  663|Homo sapiens protein ( Homo sapiens ...    32   2.0  

>AL513122-4|CAI14414.1|  228|Homo sapiens gelsolin (amyloidosis,
           Finnish type) protein.
          Length = 228

 Score =  218 bits (532), Expect = 2e-56
 Identities = 105/215 (48%), Positives = 142/215 (66%), Gaps = 1/215 (0%)
 Frame = +3

Query: 3   CTRPKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD- 179
           C    M   H  F  AG++PGL+IWR+E F+ V VP   +G F++GD+Y++L T   ++ 
Sbjct: 7   CFPNSMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNG 66

Query: 180 RLTWDIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAI 359
            L +D+H+WLG+  SQDE+GAAAI TV LDD    G AVQHREVQ +ES  FL YF   +
Sbjct: 67  NLQYDLHYWLGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYFKSGL 125

Query: 360 RYLKGGHASGFSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIF 539
           +Y KGG ASGF HV  NE   +RLFQ+KG+R VR  +V  ++ES NNGDCFILD+ + I 
Sbjct: 126 KYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIH 185

Query: 540 VFVGEKAKGVERMKAITVANQIKDQDHNGRADIEV 644
            + G  +   ER+KA  V+  I+D + +GRA + V
Sbjct: 186 QWCGSNSNRYERLKATQVSKGIRDNERSGRARVHV 220


>X04412-1|CAA28000.1|  782|Homo sapiens plasma gelsolin protein.
          Length = 782

 Score =  217 bits (530), Expect = 3e-56
 Identities = 103/206 (50%), Positives = 140/206 (67%), Gaps = 1/206 (0%)
 Frame = +3

Query: 30  HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 206
           H  F  AG++PGL+IWR+E F+ V VP   +G F++GD+Y++L T   ++  L +D+H+W
Sbjct: 56  HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 115

Query: 207 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHAS 386
           LG+  SQDE+GAAAI TV LDD    G AVQHREVQ +ES  FL YF   ++Y KGG AS
Sbjct: 116 LGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVAS 174

Query: 387 GFSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKG 566
           GF HV  NE   +RLFQ+KG+R VR  +V  ++ES NNGDCFILD+ + I  + G  +  
Sbjct: 175 GFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNR 234

Query: 567 VERMKAITVANQIKDQDHNGRADIEV 644
            ER+KA  V+  I+D + +GRA + V
Sbjct: 235 YERLKATQVSKGIRDNERSGRARVHV 260



 Score = 91.9 bits (218), Expect = 2e-18
 Identities = 66/186 (35%), Positives = 91/186 (48%), Gaps = 4/186 (2%)
 Frame = +3

Query: 69  EIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAAA 248
           +IWRIE    V V    +G FY GDSYI+L       R    I+ W G++++QDE  A+A
Sbjct: 448 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASA 507

Query: 249 ILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYLKGGHASGFSHVTINEGTE 422
           ILT  L DE+  G+ VQ R VQ  E    +  F   P I Y KGG  S     T    T 
Sbjct: 508 ILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIY-KGG-TSREGGQTAPAST- 563

Query: 423 KRLFQIKGKR--NVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVA 596
            RLFQ++       R  +V P   +LN+ D F+L      +++VG  A   E+  A  + 
Sbjct: 564 -RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELL 622

Query: 597 NQIKDQ 614
             ++ Q
Sbjct: 623 RVLRAQ 628



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 42/159 (26%), Positives = 71/159 (44%), Gaps = 8/159 (5%)
 Frame = +3

Query: 192 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLK 371
           +IH W GS +++ E   A  ++  + D +  G A  H   +  E +  L+   P    L 
Sbjct: 223 NIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPK-PALP 281

Query: 372 GGHASGFSHVTINEGTEKRLFQIK---GKRNVRVKQVKPTFE--SLNNGDCFILD--VDH 530
            G          N    K L+++    G  +V +   +  F   +L + DCFILD   D 
Sbjct: 282 AGTEDTAKEDAANRKLAK-LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDG 340

Query: 531 QIFVFVGEKAKGVERMKAI-TVANQIKDQDHNGRADIEV 644
           +IFV+ G++A   ER  A+ T ++ I   D+  +  + V
Sbjct: 341 KIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSV 379



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 16/48 (33%), Positives = 27/48 (56%)
 Frame = +3

Query: 486 ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 629
           E L   D  +LD   Q+FV+VG+ ++  E+ +A+T A +  + D   R
Sbjct: 691 EDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANR 738


>BC026033-1|AAH26033.1|  782|Homo sapiens gelsolin (amyloidosis,
           Finnish type) protein.
          Length = 782

 Score =  217 bits (530), Expect = 3e-56
 Identities = 103/206 (50%), Positives = 140/206 (67%), Gaps = 1/206 (0%)
 Frame = +3

Query: 30  HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 206
           H  F  AG++PGL+IWR+E F+ V VP   +G F++GD+Y++L T   ++  L +D+H+W
Sbjct: 56  HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 115

Query: 207 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHAS 386
           LG+  SQDE+GAAAI TV LDD    G AVQHREVQ +ES  FL YF   ++Y KGG AS
Sbjct: 116 LGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVAS 174

Query: 387 GFSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKG 566
           GF HV  NE   +RLFQ+KG+R VR  +V  ++ES NNGDCFILD+ + I  + G  +  
Sbjct: 175 GFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNR 234

Query: 567 VERMKAITVANQIKDQDHNGRADIEV 644
            ER+KA  V+  I+D + +GRA + V
Sbjct: 235 YERLKATQVSKGIRDNERSGRARVHV 260



 Score = 91.9 bits (218), Expect = 2e-18
 Identities = 66/186 (35%), Positives = 91/186 (48%), Gaps = 4/186 (2%)
 Frame = +3

Query: 69  EIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAAA 248
           +IWRIE    V V    +G FY GDSYI+L       R    I+ W G++++QDE  A+A
Sbjct: 448 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASA 507

Query: 249 ILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYLKGGHASGFSHVTINEGTE 422
           ILT  L DE+  G+ VQ R VQ  E    +  F   P I Y KGG  S     T    T 
Sbjct: 508 ILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIY-KGG-TSREGGQTAPAST- 563

Query: 423 KRLFQIKGKR--NVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVA 596
            RLFQ++       R  +V P   +LN+ D F+L      +++VG  A   E+  A  + 
Sbjct: 564 -RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELL 622

Query: 597 NQIKDQ 614
             ++ Q
Sbjct: 623 RVLRAQ 628



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 42/159 (26%), Positives = 71/159 (44%), Gaps = 8/159 (5%)
 Frame = +3

Query: 192 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLK 371
           +IH W GS +++ E   A  ++  + D +  G A  H   +  E +  L+   P    L 
Sbjct: 223 NIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPK-PALP 281

Query: 372 GGHASGFSHVTINEGTEKRLFQIK---GKRNVRVKQVKPTFE--SLNNGDCFILD--VDH 530
            G          N    K L+++    G  +V +   +  F   +L + DCFILD   D 
Sbjct: 282 AGTEDTAKEDAANRKLAK-LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDG 340

Query: 531 QIFVFVGEKAKGVERMKAI-TVANQIKDQDHNGRADIEV 644
           +IFV+ G++A   ER  A+ T ++ I   D+  +  + V
Sbjct: 341 KIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSV 379



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 16/48 (33%), Positives = 27/48 (56%)
 Frame = +3

Query: 486 ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 629
           E L   D  +LD   Q+FV+VG+ ++  E+ +A+T A +  + D   R
Sbjct: 691 EDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANR 738


>AL513122-6|CAM20459.1|  731|Homo sapiens gelsolin (amyloidosis,
           Finnish type) protein.
          Length = 731

 Score =  217 bits (530), Expect = 3e-56
 Identities = 103/206 (50%), Positives = 140/206 (67%), Gaps = 1/206 (0%)
 Frame = +3

Query: 30  HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 206
           H  F  AG++PGL+IWR+E F+ V VP   +G F++GD+Y++L T   ++  L +D+H+W
Sbjct: 5   HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 64

Query: 207 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHAS 386
           LG+  SQDE+GAAAI TV LDD    G AVQHREVQ +ES  FL YF   ++Y KGG AS
Sbjct: 65  LGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVAS 123

Query: 387 GFSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKG 566
           GF HV  NE   +RLFQ+KG+R VR  +V  ++ES NNGDCFILD+ + I  + G  +  
Sbjct: 124 GFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNR 183

Query: 567 VERMKAITVANQIKDQDHNGRADIEV 644
            ER+KA  V+  I+D + +GRA + V
Sbjct: 184 YERLKATQVSKGIRDNERSGRARVHV 209



 Score = 91.9 bits (218), Expect = 2e-18
 Identities = 66/186 (35%), Positives = 91/186 (48%), Gaps = 4/186 (2%)
 Frame = +3

Query: 69  EIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAAA 248
           +IWRIE    V V    +G FY GDSYI+L       R    I+ W G++++QDE  A+A
Sbjct: 397 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASA 456

Query: 249 ILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYLKGGHASGFSHVTINEGTE 422
           ILT  L DE+  G+ VQ R VQ  E    +  F   P I Y KGG  S     T    T 
Sbjct: 457 ILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIY-KGG-TSREGGQTAPAST- 512

Query: 423 KRLFQIKGKR--NVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVA 596
            RLFQ++       R  +V P   +LN+ D F+L      +++VG  A   E+  A  + 
Sbjct: 513 -RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELL 571

Query: 597 NQIKDQ 614
             ++ Q
Sbjct: 572 RVLRAQ 577



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 42/159 (26%), Positives = 71/159 (44%), Gaps = 8/159 (5%)
 Frame = +3

Query: 192 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLK 371
           +IH W GS +++ E   A  ++  + D +  G A  H   +  E +  L+   P    L 
Sbjct: 172 NIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPK-PALP 230

Query: 372 GGHASGFSHVTINEGTEKRLFQIK---GKRNVRVKQVKPTFE--SLNNGDCFILD--VDH 530
            G          N    K L+++    G  +V +   +  F   +L + DCFILD   D 
Sbjct: 231 AGTEDTAKEDAANRKLAK-LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDG 289

Query: 531 QIFVFVGEKAKGVERMKAI-TVANQIKDQDHNGRADIEV 644
           +IFV+ G++A   ER  A+ T ++ I   D+  +  + V
Sbjct: 290 KIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSV 328



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 16/48 (33%), Positives = 27/48 (56%)
 Frame = +3

Query: 486 ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 629
           E L   D  +LD   Q+FV+VG+ ++  E+ +A+T A +  + D   R
Sbjct: 640 EDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANR 687


>AL513122-5|CAI14415.1|  260|Homo sapiens gelsolin (amyloidosis,
           Finnish type) protein.
          Length = 260

 Score =  217 bits (530), Expect = 3e-56
 Identities = 103/206 (50%), Positives = 140/206 (67%), Gaps = 1/206 (0%)
 Frame = +3

Query: 30  HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 206
           H  F  AG++PGL+IWR+E F+ V VP   +G F++GD+Y++L T   ++  L +D+H+W
Sbjct: 5   HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 64

Query: 207 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHAS 386
           LG+  SQDE+GAAAI TV LDD    G AVQHREVQ +ES  FL YF   ++Y KGG AS
Sbjct: 65  LGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVAS 123

Query: 387 GFSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKG 566
           GF HV  NE   +RLFQ+KG+R VR  +V  ++ES NNGDCFILD+ + I  + G  +  
Sbjct: 124 GFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNR 183

Query: 567 VERMKAITVANQIKDQDHNGRADIEV 644
            ER+KA  V+  I+D + +GRA + V
Sbjct: 184 YERLKATQVSKGIRDNERSGRARVHV 209


>AL513122-3|CAI14413.1|  782|Homo sapiens gelsolin (amyloidosis,
           Finnish type) protein.
          Length = 782

 Score =  217 bits (530), Expect = 3e-56
 Identities = 103/206 (50%), Positives = 140/206 (67%), Gaps = 1/206 (0%)
 Frame = +3

Query: 30  HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 206
           H  F  AG++PGL+IWR+E F+ V VP   +G F++GD+Y++L T   ++  L +D+H+W
Sbjct: 56  HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 115

Query: 207 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHAS 386
           LG+  SQDE+GAAAI TV LDD    G AVQHREVQ +ES  FL YF   ++Y KGG AS
Sbjct: 116 LGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVAS 174

Query: 387 GFSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKG 566
           GF HV  NE   +RLFQ+KG+R VR  +V  ++ES NNGDCFILD+ + I  + G  +  
Sbjct: 175 GFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNR 234

Query: 567 VERMKAITVANQIKDQDHNGRADIEV 644
            ER+KA  V+  I+D + +GRA + V
Sbjct: 235 YERLKATQVSKGIRDNERSGRARVHV 260



 Score = 91.9 bits (218), Expect = 2e-18
 Identities = 66/186 (35%), Positives = 91/186 (48%), Gaps = 4/186 (2%)
 Frame = +3

Query: 69  EIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAAA 248
           +IWRIE    V V    +G FY GDSYI+L       R    I+ W G++++QDE  A+A
Sbjct: 448 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASA 507

Query: 249 ILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYLKGGHASGFSHVTINEGTE 422
           ILT  L DE+  G+ VQ R VQ  E    +  F   P I Y KGG  S     T    T 
Sbjct: 508 ILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIY-KGG-TSREGGQTAPAST- 563

Query: 423 KRLFQIKGKR--NVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVA 596
            RLFQ++       R  +V P   +LN+ D F+L      +++VG  A   E+  A  + 
Sbjct: 564 -RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELL 622

Query: 597 NQIKDQ 614
             ++ Q
Sbjct: 623 RVLRAQ 628



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 42/159 (26%), Positives = 71/159 (44%), Gaps = 8/159 (5%)
 Frame = +3

Query: 192 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLK 371
           +IH W GS +++ E   A  ++  + D +  G A  H   +  E +  L+   P    L 
Sbjct: 223 NIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPK-PALP 281

Query: 372 GGHASGFSHVTINEGTEKRLFQIK---GKRNVRVKQVKPTFE--SLNNGDCFILD--VDH 530
            G          N    K L+++    G  +V +   +  F   +L + DCFILD   D 
Sbjct: 282 AGTEDTAKEDAANRKLAK-LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDG 340

Query: 531 QIFVFVGEKAKGVERMKAI-TVANQIKDQDHNGRADIEV 644
           +IFV+ G++A   ER  A+ T ++ I   D+  +  + V
Sbjct: 341 KIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSV 379



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 16/48 (33%), Positives = 27/48 (56%)
 Frame = +3

Query: 486 ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 629
           E L   D  +LD   Q+FV+VG+ ++  E+ +A+T A +  + D   R
Sbjct: 691 EDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANR 738


>AF276507-1|AAK60494.1|  715|Homo sapiens scinderin protein.
          Length = 715

 Score =  195 bits (475), Expect = 1e-49
 Identities = 93/205 (45%), Positives = 132/205 (64%)
 Frame = +3

Query: 30  HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 209
           H+ FA AG++ GL++WRIE  E V VP++  G FY GD+Y+VL+T       T+ +HFWL
Sbjct: 7   HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWL 66

Query: 210 GSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASG 389
           G   SQDE+ AAAI TV +DD    G  VQ+RE+Q YES +F+ YF   ++Y  GG ASG
Sbjct: 67  GKECSQDESTAAAIFTVQMDD-YLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125

Query: 390 FSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGV 569
            +HV  N+ T KRL  +KG+R VR  +V  +++S N GDCFI+D+  +I+ + G      
Sbjct: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185

Query: 570 ERMKAITVANQIKDQDHNGRADIEV 644
           ER+KA  VA  I+  +  GR+++ V
Sbjct: 186 ERLKANQVATGIRYNERKGRSELIV 210



 Score = 81.4 bits (192), Expect = 3e-15
 Identities = 68/206 (33%), Positives = 97/206 (47%), Gaps = 7/206 (3%)
 Frame = +3

Query: 12  PKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTW 191
           P+M   H    D   K  +EIWR+EN   + V +  +G FY GD YI+L T   + ++  
Sbjct: 382 PQMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI-- 436

Query: 192 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRY 365
            I+ W G+  ++DE   +A LTV L D    G AVQ R  Q  E    L  F   P I Y
Sbjct: 437 -IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQDKEPVHLLSLFKDKPLIIY 494

Query: 366 LKGGHASGFSHVTINEGTEKRLFQIKGKRNV----RVKQVKPTFESLNNGDCFILDVDHQ 533
             G    G            RLFQ+  +RN+    R+ +V     SLN+ D F+L +   
Sbjct: 495 KNGTSKKGGQ----APAPPTRLFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLSQN 548

Query: 534 I-FVFVGEKAKGVERMKAITVANQIK 608
             +++VG+ A   E   A  VA+ +K
Sbjct: 549 SGYIWVGKGASQEEEKGAEYVASVLK 574



 Score = 35.1 bits (77), Expect = 0.22
 Identities = 16/50 (32%), Positives = 28/50 (56%)
 Frame = +3

Query: 480 TFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 629
           T + L   D  +LD   QIF+++G+ A  VE+ +++  A    + D +GR
Sbjct: 636 TQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGR 685


>AC005281-1|AAD15423.1|  527|Homo sapiens WUGSC:H_DJ0722F20.1
           protein.
          Length = 527

 Score =  195 bits (475), Expect = 1e-49
 Identities = 93/205 (45%), Positives = 132/205 (64%)
 Frame = +3

Query: 30  HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 209
           H+ FA AG++ GL++WRIE  E V VP++  G FY GD+Y+VL+T       T+ +HFWL
Sbjct: 7   HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWL 66

Query: 210 GSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASG 389
           G   SQDE+ AAAI TV +DD    G  VQ+RE+Q YES +F+ YF   ++Y  GG ASG
Sbjct: 67  GKECSQDESTAAAIFTVQMDD-YLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125

Query: 390 FSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGV 569
            +HV  N+ T KRL  +KG+R VR  +V  +++S N GDCFI+D+  +I+ + G      
Sbjct: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185

Query: 570 ERMKAITVANQIKDQDHNGRADIEV 644
           ER+KA  VA  I+  +  GR+++ V
Sbjct: 186 ERLKANQVATGIRYNERKGRSELIV 210



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 46/128 (35%), Positives = 61/128 (47%), Gaps = 2/128 (1%)
 Frame = +3

Query: 12  PKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTW 191
           P+M   H    D   K  +EIWR+EN   + V +  +G FY GD YI+L T   + ++  
Sbjct: 382 PQMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI-- 436

Query: 192 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRY 365
            I+ W G+  ++DE   +A LTV L D    G AVQ R  Q  E    L  F   P I Y
Sbjct: 437 -IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIY 494

Query: 366 LKGGHASG 389
             G    G
Sbjct: 495 KNGTSKKG 502


>AB067492-1|BAB67798.1|  626|Homo sapiens KIAA1905 protein protein.
          Length = 626

 Score =  195 bits (475), Expect = 1e-49
 Identities = 93/205 (45%), Positives = 132/205 (64%)
 Frame = +3

Query: 30  HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 209
           H+ FA AG++ GL++WRIE  E V VP++  G FY GD+Y+VL+T       T+ +HFWL
Sbjct: 53  HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWL 112

Query: 210 GSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASG 389
           G   SQDE+ AAAI TV +DD    G  VQ+RE+Q YES +F+ YF   ++Y  GG ASG
Sbjct: 113 GKECSQDESTAAAIFTVQMDD-YLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 171

Query: 390 FSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGV 569
            +HV  N+ T KRL  +KG+R VR  +V  +++S N GDCFI+D+  +I+ + G      
Sbjct: 172 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 231

Query: 570 ERMKAITVANQIKDQDHNGRADIEV 644
           ER+KA  VA  I+  +  GR+++ V
Sbjct: 232 ERLKANQVATGIRYNERKGRSELIV 256



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 46/128 (35%), Positives = 61/128 (47%), Gaps = 2/128 (1%)
 Frame = +3

Query: 12  PKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTW 191
           P+M   H    D   K  +EIWR+EN   + V +  +G FY GD YI+L T   + ++  
Sbjct: 428 PQMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI-- 482

Query: 192 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRY 365
            I+ W G+  ++DE   +A LTV L D    G AVQ R  Q  E    L  F   P I Y
Sbjct: 483 -IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIY 540

Query: 366 LKGGHASG 389
             G    G
Sbjct: 541 KNGTSKKG 548


>BC021090-1|AAH21090.1|  715|Homo sapiens SCIN protein protein.
          Length = 715

 Score =  194 bits (474), Expect = 2e-49
 Identities = 93/205 (45%), Positives = 132/205 (64%)
 Frame = +3

Query: 30  HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 209
           H+ FA AG++ GL++WRIE  E V VP++  G FY GD+Y+VL+T       T+ +HFWL
Sbjct: 7   HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYRLHFWL 66

Query: 210 GSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASG 389
           G   SQDE+ AAAI TV +DD    G  VQ+RE+Q YES +F+ YF   ++Y  GG ASG
Sbjct: 67  GKECSQDESTAAAIFTVQMDD-YLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125

Query: 390 FSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGV 569
            +HV  N+ T KRL  +KG+R VR  +V  +++S N GDCFI+D+  +I+ + G      
Sbjct: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185

Query: 570 ERMKAITVANQIKDQDHNGRADIEV 644
           ER+KA  VA  I+  +  GR+++ V
Sbjct: 186 ERLKANQVATGIRYNERKGRSELIV 210



 Score = 81.0 bits (191), Expect = 3e-15
 Identities = 68/206 (33%), Positives = 98/206 (47%), Gaps = 7/206 (3%)
 Frame = +3

Query: 12  PKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTW 191
           P+M   H    D   K  +EIWR+EN   + V +  +G FY GD YI+L T   + ++  
Sbjct: 382 PQMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI-- 436

Query: 192 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRY 365
            I+ W G+  ++DE   +A LTV L D    G AVQ R  Q  E    L  F   P I Y
Sbjct: 437 -IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIY 494

Query: 366 LKGGHASGFSHVTINEGTEKRLFQIKGKRNV----RVKQVKPTFESLNNGDCFILDV-DH 530
             G    G            RLFQ+  +RN+    R+ +V     SLN+ D F+L +  +
Sbjct: 495 KNGTSKKGGQ----APAPPTRLFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLPQN 548

Query: 531 QIFVFVGEKAKGVERMKAITVANQIK 608
             +++VG+ A   E   A  VA+ +K
Sbjct: 549 SGYIWVGKGASQEEEKGAEYVASVLK 574



 Score = 35.1 bits (77), Expect = 0.22
 Identities = 16/50 (32%), Positives = 28/50 (56%)
 Frame = +3

Query: 480 TFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 629
           T + L   D  +LD   QIF+++G+ A  VE+ +++  A    + D +GR
Sbjct: 636 TQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGR 685


>AK075123-1|BAC11416.1|  715|Homo sapiens protein ( Homo sapiens
           cDNA FLJ90642 fis, clone PLACE1004078, highly similar to
           Bovine mRNA for adseverin. ).
          Length = 715

 Score =  194 bits (472), Expect = 3e-49
 Identities = 92/205 (44%), Positives = 132/205 (64%)
 Frame = +3

Query: 30  HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 209
           H+ FA AG++ GL++WRIE  E V VP++  G FY GD+Y++L+T       T+ +HFWL
Sbjct: 7   HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLMLHTAKTSRGFTYHLHFWL 66

Query: 210 GSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASG 389
           G   SQDE+ AAAI TV +DD    G  VQ+RE+Q YES +F+ YF   ++Y  GG ASG
Sbjct: 67  GKECSQDESTAAAIFTVQMDD-YLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125

Query: 390 FSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGV 569
            +HV  N+ T KRL  +KG+R VR  +V  +++S N GDCFI+D+  +I+ + G      
Sbjct: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185

Query: 570 ERMKAITVANQIKDQDHNGRADIEV 644
           ER+KA  VA  I+  +  GR+++ V
Sbjct: 186 ERLKANQVATGIRYNERKGRSELIV 210



 Score = 81.0 bits (191), Expect = 3e-15
 Identities = 68/206 (33%), Positives = 98/206 (47%), Gaps = 7/206 (3%)
 Frame = +3

Query: 12  PKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTW 191
           P+M   H    D   K  +EIWR+EN   + V +  +G FY GD YI+L T   + ++  
Sbjct: 382 PQMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI-- 436

Query: 192 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRY 365
            I+ W G+  ++DE   +A LTV L D    G AVQ R  Q  E    L  F   P I Y
Sbjct: 437 -IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIY 494

Query: 366 LKGGHASGFSHVTINEGTEKRLFQIKGKRNV----RVKQVKPTFESLNNGDCFILDV-DH 530
             G    G            RLFQ+  +RN+    R+ +V     SLN+ D F+L +  +
Sbjct: 495 KNGTSKKGGQ----APAPPTRLFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLPQN 548

Query: 531 QIFVFVGEKAKGVERMKAITVANQIK 608
             +++VG+ A   E   A  VA+ +K
Sbjct: 549 SGYIWVGKGASQEEEKGAEYVASVLK 574



 Score = 35.1 bits (77), Expect = 0.22
 Identities = 16/50 (32%), Positives = 28/50 (56%)
 Frame = +3

Query: 480 TFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 629
           T + L   D  +LD   QIF+++G+ A  VE+ +++  A    + D +GR
Sbjct: 636 TQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGR 685


>AF041449-1|AAC25051.1|  819|Homo sapiens advillin protein.
          Length = 819

 Score =  187 bits (455), Expect = 3e-47
 Identities = 93/203 (45%), Positives = 123/203 (60%)
 Frame = +3

Query: 36  AFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGS 215
           AF      PG+ +WRIE  E   VP +  G FY GD Y++L+T      L+ DIHFW+G 
Sbjct: 6   AFRAVDNDPGIIVWRIEKMELALVPVSAHGNFYEGDCYVILSTRRVASLLSQDIHFWIGK 65

Query: 216 RTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFS 395
            +SQDE   AAI T  LDD    GS VQHREVQY+ES  F  YF   I Y +GG ASG  
Sbjct: 66  DSSQDEQSCAAIYTTQLDD-YLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMK 124

Query: 396 HVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVER 575
           HV  N    KRL  +KGKRN+R  +V+ +++S N GD F+LD+   I  + G ++   ER
Sbjct: 125 HVETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGER 184

Query: 576 MKAITVANQIKDQDHNGRADIEV 644
           +KA+ +A  I+D++  GRA+I V
Sbjct: 185 LKAMLLAKDIRDRERGGRAEIGV 207



 Score = 96.7 bits (230), Expect = 6e-20
 Identities = 67/212 (31%), Positives = 100/212 (47%), Gaps = 2/212 (0%)
 Frame = +3

Query: 6   TRPKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRL 185
           T+P++    +   D   K  +E+WRIEN E V V    +G FY GD Y+VL T     + 
Sbjct: 379 TKPEVAAQERMVDDGNGK--VEVWRIENLELVPVEYQWYGFFYGGDCYLVLYTYEVNGKP 436

Query: 186 TWDIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRY 365
              ++ W     SQDE  A+A   V + D QF G+AVQ R     E + F+  F   +  
Sbjct: 437 HHILYIWQDRHASQDELAASAYQAVEV-DRQFDGAAVQVRVRMGTEPRHFMAIFKGKLVI 495

Query: 366 LKGGHASGFSHVTINEGTEKRLFQIKG--KRNVRVKQVKPTFESLNNGDCFILDVDHQIF 539
            +GG +              RLFQI G  K N +  +V     SLN+ D F+L    + +
Sbjct: 496 FEGGTS---RKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAEHY 552

Query: 540 VFVGEKAKGVERMKAITVANQIKDQDHNGRAD 635
           ++ G+ + G ER  A  +A+ + D   N  A+
Sbjct: 553 LWYGKGSSGDERAMAKELASLLCDGSENTVAE 584



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
 Frame = +3

Query: 420 EKRLFQIKGKRN--VRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITV 593
           + RLF+   K    V  +    T + LN  D  +LD   Q+F+++G +A   E+  A+  
Sbjct: 615 QSRLFECSNKTGQFVVTEITDFTQDDLNPTDVMLLDTWDQVFLWIGAEANATEKESALAT 674

Query: 594 ANQIKDQDHNGR 629
           A Q      +GR
Sbjct: 675 AQQYLHTHPSGR 686


>X12901-1|CAA31386.1|  827|Homo sapiens protein ( Human mRNA for
           villin. ).
          Length = 827

 Score =  175 bits (427), Expect = 8e-44
 Identities = 87/195 (44%), Positives = 122/195 (62%)
 Frame = +3

Query: 60  PGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAG 239
           PGL+IWRIE  + V VP + FG F+ GD YI+L        L++DIH+W+G  +S DE G
Sbjct: 17  PGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASSLSYDIHYWIGQDSSLDEQG 76

Query: 240 AAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFSHVTINEGT 419
           AAAI T  +DD   +G AVQHREVQ  ES+ F  YF   +   KGG ASG  HV  N   
Sbjct: 77  AAAIYTTQMDDF-LKGRAVQHREVQGNESEAFRGYFKQGLVIRKGGVASGMKHVETNSYD 135

Query: 420 EKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVAN 599
            +RL  +KGKRNV   +V+ +++S N GD F+LD+   I  + G ++  +ER++ +T+A 
Sbjct: 136 VQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAK 195

Query: 600 QIKDQDHNGRADIEV 644
           +I+DQ+  GR  + V
Sbjct: 196 EIRDQERGGRTYVGV 210



 Score = 87.0 bits (206), Expect = 5e-17
 Identities = 57/182 (31%), Positives = 89/182 (48%), Gaps = 2/182 (1%)
 Frame = +3

Query: 66  LEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAA 245
           +++WRIEN E V V     G FY GD Y++L T    ++  + ++ W GS+ SQDE  A+
Sbjct: 400 VQVWRIENLELVPVDSKWLGHFYGGDCYLLLYTYLIGEKQHYLLYVWQGSQASQDEITAS 459

Query: 246 AILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFSHVTINEGTEK 425
           A   V L D+++ G  VQ R     E    +  F   +   +GG +   +   +  G   
Sbjct: 460 AYQAVIL-DQKYNGEPVQIRVPMGKEPPHLMSIFKGRMVVYQGGTSRTNN---LETGPST 515

Query: 426 RLFQIK--GKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVAN 599
           RLFQ++  G  N +  +V      LN+ D F+L      +++ G+   G ER  A  VA+
Sbjct: 516 RLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKTQSCCYLWCGKGCSGDEREMAKMVAD 575

Query: 600 QI 605
            I
Sbjct: 576 TI 577



 Score = 36.3 bits (80), Expect = 0.093
 Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
 Frame = +3

Query: 426 RLFQIKGKRNVRVKQVKPTF--ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVAN 599
           RLF+   K    +    P F  + L   D F+LDV  Q+F ++G+ A   E+  A T A 
Sbjct: 620 RLFECSNKTGRFLATEIPDFNQDDLEEDDVFLLDVWDQVFFWIGKHANEEEKKAAATTAQ 679

Query: 600 QIKDQDHNGR 629
           +      +GR
Sbjct: 680 EYLKTHPSGR 689


>BC017303-1|AAH17303.1|  421|Homo sapiens VIL1 protein protein.
          Length = 421

 Score =  175 bits (427), Expect = 8e-44
 Identities = 87/195 (44%), Positives = 122/195 (62%)
 Frame = +3

Query: 60  PGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAG 239
           PGL+IWRIE  + V VP + FG F+ GD YI+L        L++DIH+W+G  +S DE G
Sbjct: 17  PGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASSLSYDIHYWIGQDSSLDEQG 76

Query: 240 AAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFSHVTINEGT 419
           AAAI T  +DD   +G AVQHREVQ  ES+ F  YF   +   KGG ASG  HV  N   
Sbjct: 77  AAAIYTTQMDDF-LKGRAVQHREVQGNESEAFRGYFKQGLVIRKGGVASGMKHVETNSYD 135

Query: 420 EKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVAN 599
            +RL  +KGKRNV   +V+ +++S N GD F+LD+   I  + G ++  +ER++ +T+A 
Sbjct: 136 VQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAK 195

Query: 600 QIKDQDHNGRADIEV 644
           +I+DQ+  GR  + V
Sbjct: 196 EIRDQERGGRTYVGV 210


>AK223398-1|BAD97118.1|  827|Homo sapiens villin 1 variant protein.
          Length = 827

 Score =  175 bits (427), Expect = 8e-44
 Identities = 87/195 (44%), Positives = 122/195 (62%)
 Frame = +3

Query: 60  PGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAG 239
           PGL+IWRIE  + V VP + FG F+ GD YI+L        L++DIH+W+G  +S DE G
Sbjct: 17  PGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASSLSYDIHYWIGQDSSLDEQG 76

Query: 240 AAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFSHVTINEGT 419
           AAAI T  +DD   +G AVQHREVQ  ES+ F  YF   +   KGG ASG  HV  N   
Sbjct: 77  AAAIYTTQMDDF-LKGRAVQHREVQGNESEAFRGYFKQGLVIRKGGVASGMKHVETNSYD 135

Query: 420 EKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVAN 599
            +RL  +KGKRNV   +V+ +++S N GD F+LD+   I  + G ++  +ER++ +T+A 
Sbjct: 136 VQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAK 195

Query: 600 QIKDQDHNGRADIEV 644
           +I+DQ+  GR  + V
Sbjct: 196 EIRDQERGGRTYVGV 210



 Score = 87.0 bits (206), Expect = 5e-17
 Identities = 57/182 (31%), Positives = 89/182 (48%), Gaps = 2/182 (1%)
 Frame = +3

Query: 66  LEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAA 245
           +++WRIEN E V V     G FY GD Y++L T    ++  + ++ W GS+ SQDE  A+
Sbjct: 400 VQVWRIENLELVPVDSKWLGHFYGGDCYLLLYTYLIGEKQHYLLYVWQGSQASQDEITAS 459

Query: 246 AILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFSHVTINEGTEK 425
           A   V L D+++ G  VQ R     E    +  F   +   +GG +   +   +  G   
Sbjct: 460 AYQAVIL-DQKYNGEPVQIRVPMGKEPPHLMSIFKGRMVVYQGGTSRTNN---LETGPST 515

Query: 426 RLFQIK--GKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVAN 599
           RLFQ++  G  N +  +V      LN+ D F+L      +++ G+   G ER  A  VA+
Sbjct: 516 RLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKTQSCCYLWCGKGCSGDEREMAKMVAD 575

Query: 600 QI 605
            I
Sbjct: 576 TI 577



 Score = 36.3 bits (80), Expect = 0.093
 Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
 Frame = +3

Query: 426 RLFQIKGKRNVRVKQVKPTF--ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVAN 599
           RLF+   K    +    P F  + L   D F+LDV  Q+F ++G+ A   E+  A T A 
Sbjct: 620 RLFECSNKTGRFLATEIPDFNQDDLEEDDVFLLDVWDQVFFWIGKHANEEEKKAAATTAQ 679

Query: 600 QIKDQDHNGR 629
           +      +GR
Sbjct: 680 EYLKTHPSGR 689


>BC111730-1|AAI11731.1|  812|Homo sapiens AVIL protein protein.
          Length = 812

 Score =  173 bits (421), Expect = 4e-43
 Identities = 89/201 (44%), Positives = 119/201 (59%)
 Frame = +3

Query: 42  ADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRT 221
           +  G     +IW  E  E   VP +  G FY GD Y++L+T      L+ DIHFW+G  +
Sbjct: 2   SSTGHPGSYKIWG-EKMELALVPVSAHGNFYEGDCYVILSTRRVASLLSQDIHFWIGKDS 60

Query: 222 SQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFSHV 401
           SQDE   AAI T  LDD    GS VQHREVQY+ES  F  YF   I Y +GG ASG  HV
Sbjct: 61  SQDEQSCAAIYTTQLDD-YLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMKHV 119

Query: 402 TINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMK 581
             N    KRL  +KGKRN+R  +V+ +++S N GD F+LD+   I  + G ++   ER+K
Sbjct: 120 ETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERLK 179

Query: 582 AITVANQIKDQDHNGRADIEV 644
           A+ +A  I+D++  GRA+I V
Sbjct: 180 AMLLAKDIRDRERGGRAEIGV 200



 Score = 99.5 bits (237), Expect = 9e-21
 Identities = 68/212 (32%), Positives = 101/212 (47%), Gaps = 2/212 (0%)
 Frame = +3

Query: 6   TRPKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRL 185
           T+P++    +   D   K  +E+WRIEN E V V    +G FY GD Y+VL T     + 
Sbjct: 372 TKPEVAAQERMVDDGNGK--VEVWRIENLELVPVEYQWYGFFYGGDCYLVLYTYEVNGKP 429

Query: 186 TWDIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRY 365
              ++ W G   SQDE  A+A   V + D QF G+AVQ R     E + F+  F   +  
Sbjct: 430 HHILYIWQGRHASQDELAASAYQAVEV-DRQFDGAAVQVRVRMGTEPRHFMAIFKGKLVI 488

Query: 366 LKGGHASGFSHVTINEGTEKRLFQIKG--KRNVRVKQVKPTFESLNNGDCFILDVDHQIF 539
            +GG +              RLFQI G  K N +  +V     SLN+ D F+L    + +
Sbjct: 489 FEGGTS---RKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAEHY 545

Query: 540 VFVGEKAKGVERMKAITVANQIKDQDHNGRAD 635
           ++ G+ + G ER  A  +A+ + D   N  A+
Sbjct: 546 LWYGKGSSGDERAMAKELASLLCDGSENTVAE 577



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
 Frame = +3

Query: 420 EKRLFQIKGKRN--VRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITV 593
           + RLF+   K    V  +    T + LN  D  +LD   Q+F+++G +A   E+  A+  
Sbjct: 608 QSRLFECSNKTGQFVVTEITDFTQDDLNPTDVMLLDTWDQVFLWIGAEANATEKESALAT 667

Query: 594 ANQIKDQDHNGR 629
           A Q      +GR
Sbjct: 668 AQQYLHTHPSGR 679


>M94345-1|AAA59570.1|  348|Homo sapiens macrophage capping protein
           protein.
          Length = 348

 Score =  160 bits (388), Expect = 4e-39
 Identities = 80/210 (38%), Positives = 126/210 (60%), Gaps = 1/210 (0%)
 Frame = +3

Query: 18  MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 197
           +P+    F  + + PGL +WR+E  +PV V +   G+F+SGDSY+VL+   ++      +
Sbjct: 5   IPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEE---VSHL 61

Query: 198 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 377
           H W+G ++S+DE GA A+L V+L+    +   VQHREVQ  ES  F+ YF   ++Y +GG
Sbjct: 62  HLWIGQQSSRDEQGACAVLAVHLNTLLGE-RPVQHREVQGNESDLFMSYFPRGLKYQEGG 120

Query: 378 HASGFSHVTINEGTE-KRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGE 554
             S F   +       K+L+Q+KGK+N+R  +    ++S N GDCFILD+   IF + G 
Sbjct: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGG 180

Query: 555 KAKGVERMKAITVANQIKDQDHNGRADIEV 644
           K+  +ER KA  +A  I+D +  G+A +E+
Sbjct: 181 KSNILERNKARDLALAIRDSERQGKAQVEI 210


>BC014549-1|AAH14549.1|  348|Homo sapiens capping protein (actin
           filament), gelsolin-like protein.
          Length = 348

 Score =  160 bits (388), Expect = 4e-39
 Identities = 80/210 (38%), Positives = 126/210 (60%), Gaps = 1/210 (0%)
 Frame = +3

Query: 18  MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 197
           +P+    F  + + PGL +WR+E  +PV V +   G+F+SGDSY+VL+   ++      +
Sbjct: 5   IPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEE---VSHL 61

Query: 198 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 377
           H W+G ++S+DE GA A+L V+L+    +   VQHREVQ  ES  F+ YF   ++Y +GG
Sbjct: 62  HLWIGQQSSRDEQGACAVLAVHLNTLLGE-RPVQHREVQGNESDLFMSYFPRGLKYQEGG 120

Query: 378 HASGFSHVTINEGTE-KRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGE 554
             S F   +       K+L+Q+KGK+N+R  +    ++S N GDCFILD+   IF + G 
Sbjct: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGG 180

Query: 555 KAKGVERMKAITVANQIKDQDHNGRADIEV 644
           K+  +ER KA  +A  I+D +  G+A +E+
Sbjct: 181 KSNILERNKARDLALAIRDSERQGKAQVEI 210


>BC000728-1|AAH00728.1|  348|Homo sapiens capping protein (actin
           filament), gelsolin-like protein.
          Length = 348

 Score =  160 bits (388), Expect = 4e-39
 Identities = 80/210 (38%), Positives = 126/210 (60%), Gaps = 1/210 (0%)
 Frame = +3

Query: 18  MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 197
           +P+    F  + + PGL +WR+E  +PV V +   G+F+SGDSY+VL+   ++      +
Sbjct: 5   IPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEE---VSHL 61

Query: 198 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 377
           H W+G ++S+DE GA A+L V+L+    +   VQHREVQ  ES  F+ YF   ++Y +GG
Sbjct: 62  HLWIGQQSSRDEQGACAVLAVHLNTLLGE-RPVQHREVQGNESDLFMSYFPRGLKYQEGG 120

Query: 378 HASGFSHVTINEGTE-KRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGE 554
             S F   +       K+L+Q+KGK+N+R  +    ++S N GDCFILD+   IF + G 
Sbjct: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGG 180

Query: 555 KAKGVERMKAITVANQIKDQDHNGRADIEV 644
           K+  +ER KA  +A  I+D +  G+A +E+
Sbjct: 181 KSNILERNKARDLALAIRDSERQGKAQVEI 210


>AC062037-3|AAY24128.1|  348|Homo sapiens unknown protein.
          Length = 348

 Score =  160 bits (388), Expect = 4e-39
 Identities = 80/210 (38%), Positives = 126/210 (60%), Gaps = 1/210 (0%)
 Frame = +3

Query: 18  MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 197
           +P+    F  + + PGL +WR+E  +PV V +   G+F+SGDSY+VL+   ++      +
Sbjct: 5   IPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEE---VSHL 61

Query: 198 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 377
           H W+G ++S+DE GA A+L V+L+    +   VQHREVQ  ES  F+ YF   ++Y +GG
Sbjct: 62  HLWIGQQSSRDEQGACAVLAVHLNTLLGE-RPVQHREVQGNESDLFMSYFPRGLKYQEGG 120

Query: 378 HASGFSHVTINEGTE-KRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGE 554
             S F   +       K+L+Q+KGK+N+R  +    ++S N GDCFILD+   IF + G 
Sbjct: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGG 180

Query: 555 KAKGVERMKAITVANQIKDQDHNGRADIEV 644
           K+  +ER KA  +A  I+D +  G+A +E+
Sbjct: 181 KSNILERNKARDLALAIRDSERQGKAQVEI 210


>U12026-1|AAA92670.1|  172|Homo sapiens Cap-G protein.
          Length = 172

 Score =  133 bits (321), Expect = 6e-31
 Identities = 66/170 (38%), Positives = 102/170 (60%), Gaps = 1/170 (0%)
 Frame = +3

Query: 18  MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 197
           +P+    F  + + PGL +WR+E  +PV V +   G+F+SGDSY+VL+   ++      +
Sbjct: 5   IPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEE---VSHL 61

Query: 198 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 377
           H W+G ++S+DE GA A+L V+L +       VQHREVQ  ES  F+ YF   ++Y +GG
Sbjct: 62  HLWIGQQSSRDEQGACAVLAVHL-NTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG 120

Query: 378 HASGFSHVTIN-EGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDV 524
             S F   +       K+L+Q+KGK+N+R  +    ++S N GDCFILD+
Sbjct: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDL 170


>U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein.
          Length = 1269

 Score =  124 bits (300), Expect = 2e-28
 Identities = 73/200 (36%), Positives = 110/200 (55%), Gaps = 2/200 (1%)
 Frame = +3

Query: 45   DAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNT-TGDKDRLTWDIHFWLGSRT 221
            D G+ PGL IW+IENF PV V +   G FY  D YIVL T   D   L W+I++W+G   
Sbjct: 494  DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 553

Query: 222  SQDEAGAAAILTVNLDDEQFQGSAVQH-REVQYYESKEFLEYFSPAIRYLKGGHASGFSH 398
            + D+   +AI  VNL    + G+  +  RE    ES+EFL+ F   I Y++GG ASGF +
Sbjct: 554  TLDKKACSAIHAVNL--RNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGF-Y 610

Query: 399  VTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERM 578
               +     R++++ GK+N++++ V     SL+    F+LD    I+V+ G +A      
Sbjct: 611  TVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTT 670

Query: 579  KAITVANQIKDQDHNGRADI 638
            KA   A +I   +  G+A+I
Sbjct: 671  KARLFAEKINKNERKGKAEI 690


>U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog protein.
          Length = 1268

 Score =  124 bits (300), Expect = 2e-28
 Identities = 73/200 (36%), Positives = 110/200 (55%), Gaps = 2/200 (1%)
 Frame = +3

Query: 45   DAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNT-TGDKDRLTWDIHFWLGSRT 221
            D G+ PGL IW+IENF PV V +   G FY  D YIVL T   D   L W+I++W+G   
Sbjct: 493  DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 552

Query: 222  SQDEAGAAAILTVNLDDEQFQGSAVQH-REVQYYESKEFLEYFSPAIRYLKGGHASGFSH 398
            + D+   +AI  VNL    + G+  +  RE    ES+EFL+ F   I Y++GG ASGF +
Sbjct: 553  TLDKKACSAIHAVNL--RNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGF-Y 609

Query: 399  VTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERM 578
               +     R++++ GK+N++++ V     SL+    F+LD    I+V+ G +A      
Sbjct: 610  TVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTT 669

Query: 579  KAITVANQIKDQDHNGRADI 638
            KA   A +I   +  G+A+I
Sbjct: 670  KARLFAEKINKNERKGKAEI 689


>BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog
            (Drosophila) protein.
          Length = 1269

 Score =  124 bits (300), Expect = 2e-28
 Identities = 73/200 (36%), Positives = 110/200 (55%), Gaps = 2/200 (1%)
 Frame = +3

Query: 45   DAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNT-TGDKDRLTWDIHFWLGSRT 221
            D G+ PGL IW+IENF PV V +   G FY  D YIVL T   D   L W+I++W+G   
Sbjct: 494  DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 553

Query: 222  SQDEAGAAAILTVNLDDEQFQGSAVQH-REVQYYESKEFLEYFSPAIRYLKGGHASGFSH 398
            + D+   +AI  VNL    + G+  +  RE    ES+EFL+ F   I Y++GG ASGF +
Sbjct: 554  TLDKKACSAIHAVNL--RNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGF-Y 610

Query: 399  VTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERM 578
               +     R++++ GK+N++++ V     SL+    F+LD    I+V+ G +A      
Sbjct: 611  TVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTT 670

Query: 579  KAITVANQIKDQDHNGRADI 638
            KA   A +I   +  G+A+I
Sbjct: 671  KARLFAEKINKNERKGKAEI 690


>AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog variant
            protein.
          Length = 1101

 Score =  124 bits (300), Expect = 2e-28
 Identities = 73/200 (36%), Positives = 110/200 (55%), Gaps = 2/200 (1%)
 Frame = +3

Query: 45   DAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNT-TGDKDRLTWDIHFWLGSRT 221
            D G+ PGL IW+IENF PV V +   G FY  D YIVL T   D   L W+I++W+G   
Sbjct: 481  DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 540

Query: 222  SQDEAGAAAILTVNLDDEQFQGSAVQH-REVQYYESKEFLEYFSPAIRYLKGGHASGFSH 398
            + D+   +AI  VNL    + G+  +  RE    ES+EFL+ F   I Y++GG ASGF +
Sbjct: 541  TLDKKACSAIHAVNL--RNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGF-Y 597

Query: 399  VTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERM 578
               +     R++++ GK+N++++ V     SL+    F+LD    I+V+ G +A      
Sbjct: 598  TVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTT 657

Query: 579  KAITVANQIKDQDHNGRADI 638
            KA   A +I   +  G+A+I
Sbjct: 658  KARLFAEKINKNERKGKAEI 677


>AL513122-7|CAI14416.1|  485|Homo sapiens gelsolin (amyloidosis,
           Finnish type) protein.
          Length = 485

 Score = 91.9 bits (218), Expect = 2e-18
 Identities = 66/186 (35%), Positives = 91/186 (48%), Gaps = 4/186 (2%)
 Frame = +3

Query: 69  EIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAAA 248
           +IWRIE    V V    +G FY GDSYI+L       R    I+ W G++++QDE  A+A
Sbjct: 179 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASA 238

Query: 249 ILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYLKGGHASGFSHVTINEGTE 422
           ILT  L DE+  G+ VQ R VQ  E    +  F   P I Y KGG  S     T    T 
Sbjct: 239 ILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIY-KGG-TSREGGQTAPAST- 294

Query: 423 KRLFQIKGKR--NVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVA 596
            RLFQ++       R  +V P   +LN+ D F+L      +++VG  A   E+  A  + 
Sbjct: 295 -RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELL 353

Query: 597 NQIKDQ 614
             ++ Q
Sbjct: 354 RVLRAQ 359


>AK075198-1|BAC11465.1|  396|Homo sapiens protein ( Homo sapiens
           cDNA FLJ90717 fis, clone PLACE1008657, highly similar to
           Bovine mRNA for adseverin. ).
          Length = 396

 Score = 81.0 bits (191), Expect = 3e-15
 Identities = 68/206 (33%), Positives = 98/206 (47%), Gaps = 7/206 (3%)
 Frame = +3

Query: 12  PKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTW 191
           P+M   H    D   K  +EIWR+EN   + V +  +G FY GD YI+L T   + ++  
Sbjct: 63  PQMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI-- 117

Query: 192 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRY 365
            I+ W G+  ++DE   +A LTV L D    G AVQ R  Q  E    L  F   P I Y
Sbjct: 118 -IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIY 175

Query: 366 LKGGHASGFSHVTINEGTEKRLFQIKGKRNV----RVKQVKPTFESLNNGDCFILDV-DH 530
             G    G            RLFQ+  +RN+    R+ +V     SLN+ D F+L +  +
Sbjct: 176 KNGTSKKGGQ----APAPPTRLFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLPQN 229

Query: 531 QIFVFVGEKAKGVERMKAITVANQIK 608
             +++VG+ A   E   A  VA+ +K
Sbjct: 230 SGYIWVGKGASQEEEKGAEYVASVLK 255



 Score = 35.1 bits (77), Expect = 0.22
 Identities = 16/50 (32%), Positives = 28/50 (56%)
 Frame = +3

Query: 480 TFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 629
           T + L   D  +LD   QIF+++G+ A  VE+ +++  A    + D +GR
Sbjct: 317 TQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGR 366


>AK027778-1|BAB55361.1|  468|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14872 fis, clone PLACE1002655, highly similar to
           ADSEVERIN. ).
          Length = 468

 Score = 81.0 bits (191), Expect = 3e-15
 Identities = 68/206 (33%), Positives = 98/206 (47%), Gaps = 7/206 (3%)
 Frame = +3

Query: 12  PKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTW 191
           P+M   H    D   K  +EIWR+EN   + V +  +G FY GD YI+L T   + ++  
Sbjct: 135 PQMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI-- 189

Query: 192 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRY 365
            I+ W G+  ++DE   +A LTV L D    G AVQ R  Q  E    L  F   P I Y
Sbjct: 190 -IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIY 247

Query: 366 LKGGHASGFSHVTINEGTEKRLFQIKGKRNV----RVKQVKPTFESLNNGDCFILDV-DH 530
             G    G            RLFQ+  +RN+    R+ +V     SLN+ D F+L +  +
Sbjct: 248 KNGTSKKGGQ----APAPPTRLFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLPQN 301

Query: 531 QIFVFVGEKAKGVERMKAITVANQIK 608
             +++VG+ A   E   A  VA+ +K
Sbjct: 302 SGYIWVGKGASQEEEKGAEYVASVLK 327



 Score = 35.1 bits (77), Expect = 0.22
 Identities = 16/50 (32%), Positives = 28/50 (56%)
 Frame = +3

Query: 480 TFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 629
           T + L   D  +LD   QIF+++G+ A  VE+ +++  A    + D +GR
Sbjct: 389 TQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGR 438


>BC075797-1|AAH75797.1|   85|Homo sapiens Unknown (protein for
           MGC:87550) protein.
          Length = 85

 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 30/61 (49%), Positives = 42/61 (68%)
 Frame = +3

Query: 30  HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 209
           H+ FA AG++ GL++WRIE  E V VP++  G FY GD+Y+VL+T       T+ +HFWL
Sbjct: 7   HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWL 66

Query: 210 G 212
           G
Sbjct: 67  G 67


>X07066-1|CAA30102.1|   69|Homo sapiens protein ( Human gene for
           gelsolin exon 4. ).
          Length = 69

 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 28/62 (45%), Positives = 44/62 (70%), Gaps = 1/62 (1%)
 Frame = +3

Query: 30  HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 206
           H  F  AG++PGL+IWR+E F+ V VP   +G F++GD+Y++L T   ++  L +D+H+W
Sbjct: 8   HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 67

Query: 207 LG 212
           LG
Sbjct: 68  LG 69


>D88154-1|BAA21668.1|  686|Homo sapiens villin-like protein protein.
          Length = 686

 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 55/205 (26%), Positives = 85/205 (41%), Gaps = 5/205 (2%)
 Frame = +3

Query: 6   TRPKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRL 185
           T+PK+    +   D   K  +E+W I++     V   + G   +G+ Y+VL T     R+
Sbjct: 205 TQPKLAAQLRMVDDGSGK--VEVWCIQDLHRQPVDPKRHGQLCAGNCYLVLYTYQRLGRV 262

Query: 186 TWDIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRY 365
            + ++ W G + + DE  A       L D  + G  VQ       E   FL  F   +  
Sbjct: 263 QYILYLWQGHQATADEIEALNSNAEEL-DVMYGGVLVQEHVTMGSEPPHFLAIFQGQLVI 321

Query: 366 LK---GGHASGFSHVTINEGTEKRLFQIKG--KRNVRVKQVKPTFESLNNGDCFILDVDH 530
            +   G H  G S  T       RLFQ++G    N R  +V     SLN+ D F+L    
Sbjct: 322 FQERAGHHGKGQSAST------TRLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTAS 375

Query: 531 QIFVFVGEKAKGVERMKAITVANQI 605
             +++ G+   G +R  A  V   I
Sbjct: 376 VCYLWFGKGCNGDQREMARVVVTVI 400


>BC004300-1|AAH04300.1|  672|Homo sapiens VILL protein protein.
          Length = 672

 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 55/205 (26%), Positives = 85/205 (41%), Gaps = 5/205 (2%)
 Frame = +3

Query: 6   TRPKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRL 185
           T+PK+    +   D   K  +E+W I++     V   + G   +G+ Y+VL T     R+
Sbjct: 191 TQPKLAAQLRMVDDGSGK--VEVWCIQDLHRQPVDPKRHGQLCAGNCYLVLYTYQRLGRV 248

Query: 186 TWDIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRY 365
            + ++ W G + + DE  A       L D  + G  VQ       E   FL  F   +  
Sbjct: 249 QYILYLWQGHQATADEIEALNSNAEEL-DVMYGGVLVQEHVTMGSEPPHFLAIFQGQLVI 307

Query: 366 LK---GGHASGFSHVTINEGTEKRLFQIKG--KRNVRVKQVKPTFESLNNGDCFILDVDH 530
            +   G H  G S  T       RLFQ++G    N R  +V     SLN+ D F+L    
Sbjct: 308 FQERAGHHGKGQSAST------TRLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTAS 361

Query: 531 QIFVFVGEKAKGVERMKAITVANQI 605
             +++ G+   G +R  A  V   I
Sbjct: 362 VCYLWFGKGCNGDQREMARVVVTVI 386


>BC000243-1|AAH00243.1|  686|Homo sapiens VILL protein protein.
          Length = 686

 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 55/205 (26%), Positives = 85/205 (41%), Gaps = 5/205 (2%)
 Frame = +3

Query: 6   TRPKMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRL 185
           T+PK+    +   D   K  +E+W I++     V   + G   +G+ Y+VL T     R+
Sbjct: 205 TQPKLAAQLRMVDDGSGK--VEVWCIQDLHRQPVDPKRHGQLCAGNCYLVLYTYQRLGRV 262

Query: 186 TWDIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRY 365
            + ++ W G + + DE  A       L D  + G  VQ       E   FL  F   +  
Sbjct: 263 QYILYLWQGHQATADEIEALNSNAEEL-DVMYGGVLVQEHVTMGSEPPHFLAIFQGQLVI 321

Query: 366 LK---GGHASGFSHVTINEGTEKRLFQIKG--KRNVRVKQVKPTFESLNNGDCFILDVDH 530
            +   G H  G S  T       RLFQ++G    N R  +V     SLN+ D F+L    
Sbjct: 322 FQERAGHHGKGQSAST------TRLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTAS 375

Query: 531 QIFVFVGEKAKGVERMKAITVANQI 605
             +++ G+   G +R  A  V   I
Sbjct: 376 VCYLWFGKGCNGDQREMARVVVTVI 400


>AL160060-2|CAH71300.1| 2214|Homo sapiens supervillin protein.
          Length = 2214

 Score = 57.6 bits (133), Expect(2) = 2e-08
 Identities = 28/66 (42%), Positives = 43/66 (65%)
 Frame = +3

Query: 429  LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIK 608
            L QIKG+R+V+ + V+P   +LN+GDCF+L   H  F++VGE A  +E+ KA  +A  I+
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504

Query: 609  DQDHNG 626
             +   G
Sbjct: 1505 TKRELG 1510



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 53/203 (26%), Positives = 94/203 (46%), Gaps = 20/203 (9%)
 Frame = +3

Query: 66   LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 200
            +++W I  F+   +PK   G F+ GD+Y+V          G + +    +          
Sbjct: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813

Query: 201  -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 377
             FW G  ++  E G +A++TV LD+E  +G+ VQ   +Q  E   FL+ F   +      
Sbjct: 1814 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1865

Query: 378  HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 545
            H+        N  +E RL+ ++G+  V   + +V     SL +     +L+V+   I+++
Sbjct: 1866 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1925

Query: 546  VGEKAKGVERMKAITVANQIKDQ 614
             G KA+   +    T AN+IK+Q
Sbjct: 1926 HGCKAQAHTKEVGRTAANKIKEQ 1948



 Score = 20.6 bits (41), Expect(2) = 2e-08
 Identities = 9/41 (21%), Positives = 20/41 (48%)
 Frame = +3

Query: 207  LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 329
            L    S++     ++ +VNL ++    SAV ++ +   + K
Sbjct: 1409 LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1449


>AL158167-3|CAI15237.1| 2214|Homo sapiens supervillin protein.
          Length = 2214

 Score = 57.6 bits (133), Expect(2) = 2e-08
 Identities = 28/66 (42%), Positives = 43/66 (65%)
 Frame = +3

Query: 429  LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIK 608
            L QIKG+R+V+ + V+P   +LN+GDCF+L   H  F++VGE A  +E+ KA  +A  I+
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504

Query: 609  DQDHNG 626
             +   G
Sbjct: 1505 TKRELG 1510



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 53/203 (26%), Positives = 94/203 (46%), Gaps = 20/203 (9%)
 Frame = +3

Query: 66   LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 200
            +++W I  F+   +PK   G F+ GD+Y+V          G + +    +          
Sbjct: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813

Query: 201  -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 377
             FW G  ++  E G +A++TV LD+E  +G+ VQ   +Q  E   FL+ F   +      
Sbjct: 1814 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1865

Query: 378  HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 545
            H+        N  +E RL+ ++G+  V   + +V     SL +     +L+V+   I+++
Sbjct: 1866 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1925

Query: 546  VGEKAKGVERMKAITVANQIKDQ 614
             G KA+   +    T AN+IK+Q
Sbjct: 1926 HGCKAQAHTKEVGRTAANKIKEQ 1948



 Score = 20.6 bits (41), Expect(2) = 2e-08
 Identities = 9/41 (21%), Positives = 20/41 (48%)
 Frame = +3

Query: 207  LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 329
            L    S++     ++ +VNL ++    SAV ++ +   + K
Sbjct: 1409 LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1449


>AF109135-1|AAD14682.1| 2214|Homo sapiens archvillin protein.
          Length = 2214

 Score = 57.6 bits (133), Expect(2) = 2e-08
 Identities = 28/66 (42%), Positives = 43/66 (65%)
 Frame = +3

Query: 429  LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIK 608
            L QIKG+R+V+ + V+P   +LN+GDCF+L   H  F++VGE A  +E+ KA  +A  I+
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504

Query: 609  DQDHNG 626
             +   G
Sbjct: 1505 TKRELG 1510



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 53/203 (26%), Positives = 94/203 (46%), Gaps = 20/203 (9%)
 Frame = +3

Query: 66   LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 200
            +++W I  F+   +PK   G F+ GD+Y+V          G + +    +          
Sbjct: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813

Query: 201  -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 377
             FW G  ++  E G +A++TV LD+E  +G+ VQ   +Q  E   FL+ F   +      
Sbjct: 1814 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1865

Query: 378  HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 545
            H+        N  +E RL+ ++G+  V   + +V     SL +     +L+V+   I+++
Sbjct: 1866 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1925

Query: 546  VGEKAKGVERMKAITVANQIKDQ 614
             G KA+   +    T AN+IK+Q
Sbjct: 1926 HGCKAQAHTKEVGRTAANKIKEQ 1948



 Score = 20.6 bits (41), Expect(2) = 2e-08
 Identities = 9/41 (21%), Positives = 20/41 (48%)
 Frame = +3

Query: 207  LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 329
            L    S++     ++ +VNL ++    SAV ++ +   + K
Sbjct: 1409 LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1449


>AL160060-1|CAH71301.1| 1788|Homo sapiens supervillin protein.
          Length = 1788

 Score = 57.6 bits (133), Expect(2) = 2e-08
 Identities = 28/66 (42%), Positives = 43/66 (65%)
 Frame = +3

Query: 429  LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIK 608
            L QIKG+R+V+ + V+P   +LN+GDCF+L   H  F++VGE A  +E+ KA  +A  I+
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078

Query: 609  DQDHNG 626
             +   G
Sbjct: 1079 TKRELG 1084



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 53/203 (26%), Positives = 94/203 (46%), Gaps = 20/203 (9%)
 Frame = +3

Query: 66   LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 200
            +++W I  F+   +PK   G F+ GD+Y+V          G + +    +          
Sbjct: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387

Query: 201  -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 377
             FW G  ++  E G +A++TV LD+E  +G+ VQ   +Q  E   FL+ F   +      
Sbjct: 1388 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1439

Query: 378  HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 545
            H+        N  +E RL+ ++G+  V   + +V     SL +     +L+V+   I+++
Sbjct: 1440 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1499

Query: 546  VGEKAKGVERMKAITVANQIKDQ 614
             G KA+   +    T AN+IK+Q
Sbjct: 1500 HGCKAQAHTKEVGRTAANKIKEQ 1522



 Score = 20.6 bits (41), Expect(2) = 2e-08
 Identities = 9/41 (21%), Positives = 20/41 (48%)
 Frame = +3

Query: 207  LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 329
            L    S++     ++ +VNL ++    SAV ++ +   + K
Sbjct: 983  LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1023


>AL158167-2|CAI15236.1| 1788|Homo sapiens supervillin protein.
          Length = 1788

 Score = 57.6 bits (133), Expect(2) = 2e-08
 Identities = 28/66 (42%), Positives = 43/66 (65%)
 Frame = +3

Query: 429  LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIK 608
            L QIKG+R+V+ + V+P   +LN+GDCF+L   H  F++VGE A  +E+ KA  +A  I+
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078

Query: 609  DQDHNG 626
             +   G
Sbjct: 1079 TKRELG 1084



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 53/203 (26%), Positives = 94/203 (46%), Gaps = 20/203 (9%)
 Frame = +3

Query: 66   LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 200
            +++W I  F+   +PK   G F+ GD+Y+V          G + +    +          
Sbjct: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387

Query: 201  -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 377
             FW G  ++  E G +A++TV LD+E  +G+ VQ   +Q  E   FL+ F   +      
Sbjct: 1388 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1439

Query: 378  HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 545
            H+        N  +E RL+ ++G+  V   + +V     SL +     +L+V+   I+++
Sbjct: 1440 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1499

Query: 546  VGEKAKGVERMKAITVANQIKDQ 614
             G KA+   +    T AN+IK+Q
Sbjct: 1500 HGCKAQAHTKEVGRTAANKIKEQ 1522



 Score = 20.6 bits (41), Expect(2) = 2e-08
 Identities = 9/41 (21%), Positives = 20/41 (48%)
 Frame = +3

Query: 207  LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 329
            L    S++     ++ +VNL ++    SAV ++ +   + K
Sbjct: 983  LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1023


>AF051851-1|AAC64696.1| 1788|Homo sapiens supervillin protein.
          Length = 1788

 Score = 57.6 bits (133), Expect(2) = 2e-08
 Identities = 28/66 (42%), Positives = 43/66 (65%)
 Frame = +3

Query: 429  LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIK 608
            L QIKG+R+V+ + V+P   +LN+GDCF+L   H  F++VGE A  +E+ KA  +A  I+
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078

Query: 609  DQDHNG 626
             +   G
Sbjct: 1079 TKRELG 1084



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 53/203 (26%), Positives = 94/203 (46%), Gaps = 20/203 (9%)
 Frame = +3

Query: 66   LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 200
            +++W I  F+   +PK   G F+ GD+Y+V          G + +    +          
Sbjct: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387

Query: 201  -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 377
             FW G  ++  E G +A++TV LD+E  +G+ VQ   +Q  E   FL+ F   +      
Sbjct: 1388 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1439

Query: 378  HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 545
            H+        N  +E RL+ ++G+  V   + +V     SL +     +L+V+   I+++
Sbjct: 1440 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1499

Query: 546  VGEKAKGVERMKAITVANQIKDQ 614
             G KA+   +    T AN+IK+Q
Sbjct: 1500 HGCKAQAHTKEVGRTAANKIKEQ 1522



 Score = 20.6 bits (41), Expect(2) = 2e-08
 Identities = 9/41 (21%), Positives = 20/41 (48%)
 Frame = +3

Query: 207  LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 329
            L    S++     ++ +VNL ++    SAV ++ +   + K
Sbjct: 983  LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1023


>AF051850-1|AAC64695.1| 1788|Homo sapiens supervillin protein.
          Length = 1788

 Score = 57.6 bits (133), Expect(2) = 2e-08
 Identities = 28/66 (42%), Positives = 43/66 (65%)
 Frame = +3

Query: 429  LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIK 608
            L QIKG+R+V+ + V+P   +LN+GDCF+L   H  F++VGE A  +E+ KA  +A  I+
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078

Query: 609  DQDHNG 626
             +   G
Sbjct: 1079 TKRELG 1084



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 53/203 (26%), Positives = 94/203 (46%), Gaps = 20/203 (9%)
 Frame = +3

Query: 66   LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 200
            +++W I  F+   +PK   G F+ GD+Y+V          G + +    +          
Sbjct: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387

Query: 201  -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 377
             FW G  ++  E G +A++TV LD+E  +G+ VQ   +Q  E   FL+ F   +      
Sbjct: 1388 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1439

Query: 378  HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 545
            H+        N  +E RL+ ++G+  V   + +V     SL +     +L+V+   I+++
Sbjct: 1440 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1499

Query: 546  VGEKAKGVERMKAITVANQIKDQ 614
             G KA+   +    T AN+IK+Q
Sbjct: 1500 HGCKAQAHTKEVGRTAANKIKEQ 1522



 Score = 20.6 bits (41), Expect(2) = 2e-08
 Identities = 9/41 (21%), Positives = 20/41 (48%)
 Frame = +3

Query: 207  LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 329
            L    S++     ++ +VNL ++    SAV ++ +   + K
Sbjct: 983  LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1023


>BC017491-1|AAH17491.1|  285|Homo sapiens Similar to gelsolin
           (amyloidosis, Finnish type) protein.
          Length = 285

 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 46/136 (33%), Positives = 65/136 (47%), Gaps = 4/136 (2%)
 Frame = +3

Query: 219 TSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYLKGGHASGF 392
           ++QDE  A+AILT  L DE+  G+ VQ R VQ  E    +  F   P I Y KGG  S  
Sbjct: 1   STQDEVAASAILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIY-KGG-TSRE 57

Query: 393 SHVTINEGTEKRLFQIKGKR--NVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKG 566
              T    T  RLFQ++       R  +V P   +LN+ D F+L      +++VG  A  
Sbjct: 58  GGQTAPAST--RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASE 115

Query: 567 VERMKAITVANQIKDQ 614
            E+  A  +   ++ Q
Sbjct: 116 AEKTGAQELLRVLRAQ 131



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 16/48 (33%), Positives = 27/48 (56%)
 Frame = +3

Query: 486 ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 629
           E L   D  +LD   Q+FV+VG+ ++  E+ +A+T A +  + D   R
Sbjct: 194 EDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANR 241


>AK092426-1|BAC03887.1|  258|Homo sapiens protein ( Homo sapiens
           cDNA FLJ35107 fis, clone PLACE6006871, moderately
           similar to SUPPRESSOR PROTEIN SRP40. ).
          Length = 258

 Score = 35.5 bits (78), Expect = 0.16
 Identities = 38/142 (26%), Positives = 65/142 (45%), Gaps = 3/142 (2%)
 Frame = +1

Query: 52  AGSRVSKYGGLRTSNRSPFRRLSSV---SSTPGTPTLY*TPQAIRTV*HGTSISGSARGP 222
           AG      GG R+S+ S    LSS    SS P + +   +P +  +     S S S+  P
Sbjct: 25  AGPNALGSGGSRSSSSSSRSILSSSILSSSIPSSSSSSSSPSSSHSS-SSPSSSHSSSSP 83

Query: 223 ARTKPARRPSSR*TWTTNNSRDQRYSTERSNITSPRSS*NISHQPSAI*KADTPQASAT* 402
           + +     PSS  + ++++S     S+  S+ +SP SS + S   S    + +P +S++ 
Sbjct: 84  SSSSSTSSPSSSSSSSSSSSPSSSNSSSSSSSSSPSSS-SSSSSSSPSSSSSSPSSSSSS 142

Query: 403 RSMREQRNDSSRSRVKETSALS 468
            S     + SS S    +S+ S
Sbjct: 143 SSSSPSSSSSSPSSSSSSSSSS 164


>BC117319-1|AAI17320.1|  257|Homo sapiens TPRXL protein protein.
          Length = 257

 Score = 33.1 bits (72), Expect = 0.87
 Identities = 36/142 (25%), Positives = 64/142 (45%), Gaps = 3/142 (2%)
 Frame = +1

Query: 52  AGSRVSKYGGLRTSNRSPFRRLSSV---SSTPGTPTLY*TPQAIRTV*HGTSISGSARGP 222
           AG      GG R+S+ S    LSS    SS P + +   +P +  +     S S S+  P
Sbjct: 25  AGPNALGSGGSRSSSSSSRSILSSSILSSSIPSSSSSSSSPSSSHSS-SSPSSSHSSSSP 83

Query: 223 ARTKPARRPSSR*TWTTNNSRDQRYSTERSNITSPRSS*NISHQPSAI*KADTPQASAT* 402
           + +     PSS  + ++++      S+  S+ +   SS + S  PS+   + +P +S++ 
Sbjct: 84  SSSSSTSSPSSSSSSSSSSPSSSNSSSSSSSSSPSSSSSSSSSSPSS--SSSSPSSSSSS 141

Query: 403 RSMREQRNDSSRSRVKETSALS 468
            S     + SS S    +S+ S
Sbjct: 142 SSSSPSSSSSSPSSSSSSSSSS 163


>AL513122-9|CAI14417.1|  207|Homo sapiens gelsolin (amyloidosis,
           Finnish type) protein.
          Length = 207

 Score = 32.3 bits (70), Expect = 1.5
 Identities = 16/48 (33%), Positives = 27/48 (56%)
 Frame = +3

Query: 486 ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 629
           E L   D  +LD   Q+FV+VG+ ++  E+ +A+T A +  + D   R
Sbjct: 116 EDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANR 163


>BC106877-1|AAI06878.1|  663|Homo sapiens chromosome 1 open reading
           frame 106 protein.
          Length = 663

 Score = 31.9 bits (69), Expect = 2.0
 Identities = 22/69 (31%), Positives = 33/69 (47%)
 Frame = -3

Query: 388 PEACPPFK*RMAGEKYSRNSLDS*YWTSRCCTADPWNCSSSKFTVRMAAAPASSWLVLEP 209
           PEA  P +  +    +   SLD  Y   R  +++PW+ SSS  T       ASS  +LEP
Sbjct: 309 PEAGSPERAPVQNSPWKETSLDHPYEKPRK-SSEPWSESSSPATTPQDGPSASSLWLLEP 367

Query: 208 SQKWMSHVR 182
           +   +  +R
Sbjct: 368 ASYHVVPIR 376


>AK001763-1|BAA91892.1|  663|Homo sapiens protein ( Homo sapiens
           cDNA FLJ10901 fis, clone NT2RP5003524. ).
          Length = 663

 Score = 31.9 bits (69), Expect = 2.0
 Identities = 22/69 (31%), Positives = 33/69 (47%)
 Frame = -3

Query: 388 PEACPPFK*RMAGEKYSRNSLDS*YWTSRCCTADPWNCSSSKFTVRMAAAPASSWLVLEP 209
           PEA  P +  +    +   SLD  Y   R  +++PW+ SSS  T       ASS  +LEP
Sbjct: 309 PEAGSPERAPVQNSPWKETSLDHPYEKPRK-SSEPWSESSSPATTPQDGPSASSLWLLEP 367

Query: 208 SQKWMSHVR 182
           +   +  +R
Sbjct: 368 ASYHVVPIR 376


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 98,586,635
Number of Sequences: 237096
Number of extensions: 2141514
Number of successful extensions: 9079
Number of sequences better than 10.0: 46
Number of HSP's better than 10.0 without gapping: 8710
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9006
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7141427170
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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