Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= epV30805
(789 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D5551D Cluster: PREDICTED: similar to Pyruvate k... 299 7e-80
UniRef50_Q4SVB7 Cluster: Pyruvate kinase; n=1; Tetraodon nigrovi... 286 5e-76
UniRef50_P30613 Cluster: Pyruvate kinase isozymes R/L; n=167; Fu... 272 7e-72
UniRef50_Q9VD23 Cluster: Pyruvate kinase; n=5; Coelomata|Rep: Py... 239 7e-62
UniRef50_Q27686 Cluster: Pyruvate kinase; n=16; Kinetoplastida|R... 229 5e-59
UniRef50_Q7RVA8 Cluster: Pyruvate kinase; n=11; Ascomycota|Rep: ... 206 5e-52
UniRef50_Q9VQH0 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P... 199 6e-50
UniRef50_Q42806 Cluster: Pyruvate kinase, cytosolic isozyme; n=6... 189 8e-47
UniRef50_P77983 Cluster: Pyruvate kinase I; n=29; Bacteria|Rep: ... 183 5e-45
UniRef50_Q9M057 Cluster: Pyruvate kinase; n=11; Magnoliophyta|Re... 182 1e-44
UniRef50_A4E9R2 Cluster: Pyruvate kinase; n=1; Collinsella aerof... 179 8e-44
UniRef50_P80885 Cluster: Pyruvate kinase; n=161; Bacteria|Rep: P... 177 2e-43
UniRef50_Q8EX62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr... 177 3e-43
UniRef50_Q9KUN0 Cluster: Pyruvate kinase; n=24; cellular organis... 173 6e-42
UniRef50_O44006 Cluster: Pyruvate kinase; n=10; cellular organis... 170 4e-41
UniRef50_P52489 Cluster: Pyruvate kinase 2; n=33; Dikarya|Rep: P... 169 7e-41
UniRef50_Q2TSW8 Cluster: Pyruvate kinase; n=4; stramenopiles|Rep... 168 1e-40
UniRef50_Q1FK29 Cluster: Pyruvate kinase; n=4; Clostridiales|Rep... 167 2e-40
UniRef50_Q2TSW6 Cluster: Pyruvate kinase; n=1; Achlya bisexualis... 166 5e-40
UniRef50_Q55863 Cluster: Pyruvate kinase 1; n=5; Cyanobacteria|R... 165 1e-39
UniRef50_Q22Z06 Cluster: Pyruvate kinase family protein; n=3; Ol... 159 6e-38
UniRef50_Q090R5 Cluster: Pyruvate kinase; n=1; Stigmatella auran... 159 1e-37
UniRef50_Q747D6 Cluster: Pyruvate kinase; n=6; Desulfuromonadale... 157 3e-37
UniRef50_Q1K4D5 Cluster: Pyruvate kinase; n=1; Desulfuromonas ac... 154 3e-36
UniRef50_Q46078 Cluster: Pyruvate kinase; n=19; Actinobacteria (... 154 3e-36
UniRef50_A7HIL5 Cluster: Pyruvate kinase; n=9; Bacteria|Rep: Pyr... 153 5e-36
UniRef50_Q08SK3 Cluster: Pyruvate kinase; n=2; Cystobacterineae|... 151 1e-35
UniRef50_A3I0G9 Cluster: Pyruvate kinase; n=3; Flexibacteraceae|... 150 4e-35
UniRef50_Q4U977 Cluster: Pyruvate kinase, putative; n=3; Piropla... 150 4e-35
UniRef50_Q81N35 Cluster: Pyruvate kinase; n=11; Bacillus cereus ... 149 1e-34
UniRef50_Q2IHE2 Cluster: Pyruvate kinase; n=1; Anaeromyxobacter ... 148 1e-34
UniRef50_Q8PYY4 Cluster: Pyruvate kinase; n=3; Methanosarcinacea... 146 7e-34
UniRef50_O06134 Cluster: Pyruvate kinase; n=29; Bacteria|Rep: Py... 145 1e-33
UniRef50_Q6MLB5 Cluster: Pyruvate kinase; n=1; Bdellovibrio bact... 144 2e-33
UniRef50_Q0W8N0 Cluster: Pyruvate kinase; n=7; cellular organism... 144 2e-33
UniRef50_Q3JCE7 Cluster: Pyruvate kinase; n=1; Nitrosococcus oce... 143 4e-33
UniRef50_Q6A9P1 Cluster: Pyruvate kinase; n=4; Actinomycetales|R... 143 5e-33
UniRef50_Q8TJ98 Cluster: Pyruvate kinase; n=2; Methanomicrobia|R... 142 9e-33
UniRef50_A7CUA8 Cluster: Pyruvate kinase; n=1; Opitutaceae bacte... 142 1e-32
UniRef50_Q1IHI1 Cluster: Pyruvate kinase; n=2; Bacteria|Rep: Pyr... 141 2e-32
UniRef50_Q1Q4I4 Cluster: Strongly similar to pyruvate kinase; n=... 141 2e-32
UniRef50_A5C814 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Re... 141 2e-32
UniRef50_Q2S3S2 Cluster: Pyruvate kinase; n=1; Salinibacter rube... 140 3e-32
UniRef50_Q2I6K6 Cluster: Pyruvate kinase; n=1; uncultured delta ... 139 6e-32
UniRef50_Q1NTW3 Cluster: Pyruvate kinase; n=1; delta proteobacte... 139 8e-32
UniRef50_Q8SQP0 Cluster: Pyruvate kinase; n=1; Encephalitozoon c... 139 8e-32
UniRef50_Q1IJ65 Cluster: Pyruvate kinase; n=6; Bacteria|Rep: Pyr... 138 1e-31
UniRef50_Q8F253 Cluster: Pyruvate kinase; n=4; Leptospira|Rep: P... 138 1e-31
UniRef50_Q6MAN9 Cluster: Pyruvate kinase; n=1; Candidatus Protoc... 138 2e-31
UniRef50_Q5V4I8 Cluster: Pyruvate kinase; n=4; Halobacteriaceae|... 137 3e-31
UniRef50_P73534 Cluster: Pyruvate kinase 2; n=37; Bacteria|Rep: ... 137 3e-31
UniRef50_Q40546 Cluster: Pyruvate kinase isozyme G, chloroplast ... 137 3e-31
UniRef50_Q56XD5 Cluster: Pyruvate kinase; n=14; Magnoliophyta|Re... 137 3e-31
UniRef50_P94685 Cluster: Pyruvate kinase; n=8; Chlamydiaceae|Rep... 136 6e-31
UniRef50_Q44473 Cluster: Pyruvate kinase; n=4; Proteobacteria|Re... 136 8e-31
UniRef50_Q9RR62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr... 135 1e-30
UniRef50_Q8YTZ8 Cluster: Pyruvate kinase; n=3; Nostocaceae|Rep: ... 134 2e-30
UniRef50_Q6AII5 Cluster: Pyruvate kinase; n=1; Desulfotalea psyc... 133 6e-30
UniRef50_Q2JLA2 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep... 132 7e-30
UniRef50_A0QNT2 Cluster: Pyruvate kinase; n=1; Mycobacterium sme... 132 1e-29
UniRef50_Q56301 Cluster: Pyruvate kinase; n=5; Thermococcaceae|R... 132 1e-29
UniRef50_Q1AXJ8 Cluster: Pyruvate kinase; n=1; Rubrobacter xylan... 131 2e-29
UniRef50_A6Q7D7 Cluster: Pyruvate kinase; n=19; cellular organis... 129 7e-29
UniRef50_Q7UF82 Cluster: Pyruvate kinase; n=1; Pirellula sp.|Rep... 128 1e-28
UniRef50_A4MK73 Cluster: Pyruvate kinase; n=1; Petrotoga mobilis... 128 1e-28
UniRef50_A0L7K0 Cluster: Pyruvate kinase; n=1; Magnetococcus sp.... 128 1e-28
UniRef50_A7D456 Cluster: Pyruvate kinase; n=2; Halobacteriaceae|... 128 2e-28
UniRef50_A6LH43 Cluster: Pyruvate kinase; n=2; Parabacteroides|R... 126 5e-28
UniRef50_Q8G5M1 Cluster: Pyruvate kinase; n=23; Actinobacteridae... 126 6e-28
UniRef50_A6FYT4 Cluster: Pyruvate kinase; n=1; Plesiocystis paci... 126 8e-28
UniRef50_UPI0000DB6F59 Cluster: PREDICTED: similar to Pyruvate k... 124 3e-27
UniRef50_A4APL1 Cluster: Pyruvate kinase; n=15; Bacteroidetes|Re... 123 4e-27
UniRef50_Q6YQT6 Cluster: Pyruvate kinase; n=6; Candidatus Phytop... 123 6e-27
UniRef50_UPI00015BD1E0 Cluster: UPI00015BD1E0 related cluster; n... 122 8e-27
UniRef50_A1BQT0 Cluster: Pyruvate kinase; n=2; Eukaryota|Rep: Py... 122 8e-27
UniRef50_A6Q5W9 Cluster: Pyruvate kinase; n=2; Epsilonproteobact... 122 1e-26
UniRef50_A6C474 Cluster: Pyruvate kinase; n=1; Planctomyces mari... 122 1e-26
UniRef50_Q6KHW9 Cluster: Pyruvate kinase; n=3; Mycoplasma|Rep: P... 121 2e-26
UniRef50_A6DH47 Cluster: Pyruvate kinase; n=1; Lentisphaera aran... 121 2e-26
UniRef50_A0L5K6 Cluster: Pyruvate kinase; n=5; Proteobacteria|Re... 118 2e-25
UniRef50_Q64MR8 Cluster: Pyruvate kinase; n=6; Bacteroides|Rep: ... 117 3e-25
UniRef50_Q82XE9 Cluster: Pyruvate kinase family; n=130; Proteoba... 117 4e-25
UniRef50_A7CAK5 Cluster: Pyruvate kinase; n=3; Ralstonia pickett... 117 4e-25
UniRef50_Q6F1U1 Cluster: Pyruvate kinase; n=10; Mollicutes|Rep: ... 115 1e-24
UniRef50_O05118 Cluster: Pyruvate kinase; n=44; Proteobacteria|R... 115 2e-24
UniRef50_Q63P20 Cluster: Pyruvate kinase; n=74; Proteobacteria|R... 113 5e-24
UniRef50_Q2TSX0 Cluster: Pyruvate kinase; n=2; cellular organism... 112 8e-24
UniRef50_UPI0000D56D72 Cluster: PREDICTED: similar to CG7070-PB,... 109 8e-23
UniRef50_Q9YEU2 Cluster: Pyruvate kinase; n=1; Aeropyrum pernix|... 109 8e-23
UniRef50_Q8ZNW0 Cluster: Pyruvate kinase II; n=173; Proteobacter... 107 3e-22
UniRef50_A1WED1 Cluster: Pyruvate kinase; n=1; Verminephrobacter... 106 5e-22
UniRef50_A1IEN3 Cluster: Pyruvate kinase; n=1; Candidatus Desulf... 105 1e-21
UniRef50_Q0C0E8 Cluster: Pyruvate kinase; n=1; Hyphomonas neptun... 105 2e-21
UniRef50_Q40545 Cluster: Pyruvate kinase isozyme A, chloroplast ... 105 2e-21
UniRef50_Q7QVW2 Cluster: Pyruvate kinase; n=1; Giardia lamblia A... 104 3e-21
UniRef50_Q0PQH4 Cluster: Pyruvate kinase; n=1; Endoriftia persep... 103 4e-21
UniRef50_Q9WY51 Cluster: Pyruvate kinase; n=3; Thermotogaceae|Re... 103 4e-21
UniRef50_O51323 Cluster: Pyruvate kinase; n=5; cellular organism... 102 9e-21
UniRef50_Q7P1G4 Cluster: Pyruvate kinase; n=4; Bacteria|Rep: Pyr... 102 1e-20
UniRef50_Q1MPC8 Cluster: Pyruvate kinase; n=4; Desulfovibrionace... 101 2e-20
UniRef50_Q07637 Cluster: Pyruvate kinase; n=44; Streptococcaceae... 101 3e-20
UniRef50_Q5ZZ75 Cluster: Pyruvate kinase II; n=4; Legionella pne... 100 4e-20
UniRef50_A7PC98 Cluster: Chromosome chr2 scaffold_11, whole geno... 100 5e-20
UniRef50_P78031 Cluster: Pyruvate kinase; n=6; Mycoplasma|Rep: P... 100 8e-20
UniRef50_A7APT5 Cluster: Pyruvate kinase family protein; n=1; Ba... 99 1e-19
UniRef50_Q8EWX2 Cluster: Pyruvate kinase; n=1; Mycoplasma penetr... 99 1e-19
UniRef50_Q9PF54 Cluster: Pyruvate kinase; n=11; Xanthomonadaceae... 98 2e-19
UniRef50_A3ZTM3 Cluster: Pyruvate kinase; n=1; Blastopirellula m... 98 3e-19
UniRef50_Q1ZJ78 Cluster: Pyruvate kinase; n=1; Psychromonas sp. ... 97 3e-19
UniRef50_Q8IJ37 Cluster: Pyruvate kinase; n=7; Plasmodium|Rep: P... 97 3e-19
UniRef50_Q04668 Cluster: Pyruvate kinase; n=2; Leishmania brazil... 97 3e-19
UniRef50_UPI0000E481DE Cluster: PREDICTED: hypothetical protein;... 96 8e-19
UniRef50_Q94KE3 Cluster: Pyruvate kinase; n=25; Magnoliophyta|Re... 95 2e-18
UniRef50_A7QH42 Cluster: Chromosome chr3 scaffold_95, whole geno... 94 4e-18
UniRef50_Q4N603 Cluster: Pyruvate kinase; n=2; Theileria|Rep: Py... 92 1e-17
UniRef50_Q0AHE3 Cluster: Pyruvate kinase; n=2; Nitrosomonadaceae... 91 2e-17
UniRef50_P32044 Cluster: Pyruvate kinase; n=2; Thermoplasma|Rep:... 90 7e-17
UniRef50_Q5C2V0 Cluster: Pyruvate kinase; n=1; Schistosoma japon... 89 1e-16
UniRef50_UPI0000DA20CA Cluster: PREDICTED: similar to Pyruvate k... 89 2e-16
UniRef50_Q9VFG4 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P... 85 2e-15
UniRef50_A3DMY9 Cluster: Pyruvate kinase; n=1; Staphylothermus m... 85 2e-15
UniRef50_Q6L281 Cluster: Pyruvate kinase; n=2; Thermoplasmatales... 85 3e-15
UniRef50_Q5IX04 Cluster: Pyruvate kinase; n=1; Prototheca wicker... 83 6e-15
UniRef50_A3ALA5 Cluster: Pyruvate kinase; n=3; Oryza sativa|Rep:... 83 8e-15
UniRef50_Q2FMN4 Cluster: Pyruvate kinase; n=1; Methanospirillum ... 83 1e-14
UniRef50_Q4YDL9 Cluster: Putative uncharacterized protein; n=1; ... 82 2e-14
UniRef50_A2BLH1 Cluster: Pyruvate kinase; n=1; Hyperthermus buty... 81 4e-14
UniRef50_UPI000155B976 Cluster: PREDICTED: similar to pyruvate k... 79 1e-13
UniRef50_A7QTW5 Cluster: Chromosome undetermined scaffold_171, w... 77 4e-13
UniRef50_A5JEK8 Cluster: Pyruvate kinase; n=1; Nosema bombycis|R... 77 4e-13
UniRef50_A1RX09 Cluster: Pyruvate kinase; n=1; Thermofilum pende... 77 7e-13
UniRef50_Q97ZD7 Cluster: Pyruvate kinase; n=4; Sulfolobaceae|Rep... 71 4e-11
UniRef50_UPI00006CE5D4 Cluster: pyruvate kinase family protein; ... 66 9e-10
UniRef50_Q9PQV7 Cluster: Pyruvate kinase; n=1; Ureaplasma parvum... 66 9e-10
UniRef50_Q7NJ33 Cluster: Pyruvate kinase; n=1; Gloeobacter viola... 66 1e-09
UniRef50_A6LTB0 Cluster: Pyruvate kinase; n=1; Clostridium beije... 66 1e-09
UniRef50_Q8MR79 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P... 64 4e-09
UniRef50_P19680 Cluster: Pyruvate kinase; n=1; Spiroplasma citri... 64 4e-09
UniRef50_Q2JJ60 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr... 63 7e-09
UniRef50_Q57572 Cluster: Pyruvate kinase; n=6; Methanococcales|R... 60 8e-08
UniRef50_A0NLM6 Cluster: Pyruvate kinase; n=2; Alphaproteobacter... 58 3e-07
UniRef50_A6PUS2 Cluster: Pyruvate kinase; n=1; Victivallis vaden... 57 4e-07
UniRef50_Q3J5D7 Cluster: Pyruvate kinase; n=2; Rhodobacter sphae... 56 8e-07
UniRef50_Q59ZE3 Cluster: Putative uncharacterized protein; n=1; ... 55 2e-06
UniRef50_P46614 Cluster: Pyruvate kinase; n=1; Candida albicans|... 54 4e-06
UniRef50_Q8XLL6 Cluster: Pyruvate kinase; n=3; Clostridium perfr... 53 9e-06
UniRef50_Q5M6U9 Cluster: Pyruvate kinase; n=2; Campylobacter jej... 51 3e-05
UniRef50_Q8FLV7 Cluster: Pyruvate kinase; n=6; Corynebacterium|R... 47 5e-04
UniRef50_A3PTF7 Cluster: Pyruvate kinase; n=5; Mycobacterium|Rep... 47 5e-04
UniRef50_Q9V2V8 Cluster: Pyruvate kinase; n=1; Thermoproteus ten... 47 5e-04
UniRef50_Q8DLH6 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep... 47 6e-04
UniRef50_Q22CT0 Cluster: Pyruvate kinase, barrel domain containi... 47 6e-04
UniRef50_Q9M3B6 Cluster: Pyruvate kinase; n=1; Arabidopsis thali... 46 8e-04
UniRef50_A4ARB8 Cluster: Pyruvate kinase; n=1; Flavobacteriales ... 45 0.002
UniRef50_UPI000049906E Cluster: pyruvate kinase; n=3; Entamoeba ... 44 0.006
UniRef50_A7QZ91 Cluster: Chromosome undetermined scaffold_267, w... 43 0.008
UniRef50_A6PU80 Cluster: Pyruvate kinase; n=1; Victivallis vaden... 43 0.010
UniRef50_A1U5Q4 Cluster: Pyruvate kinase; n=2; Marinobacter aqua... 43 0.010
UniRef50_Q5KVI2 Cluster: Pyruvate kinase; n=2; Geobacillus|Rep: ... 42 0.018
UniRef50_Q648E3 Cluster: Pyruvate kinase; n=1; uncultured archae... 41 0.031
UniRef50_Q4IUP8 Cluster: Pyruvate kinase; n=1; Azotobacter vinel... 41 0.041
UniRef50_A4VPY3 Cluster: Pyruvate kinase; n=1; Pseudomonas stutz... 40 0.071
UniRef50_Q9VVH0 Cluster: CG12229-PA; n=2; Sophophora|Rep: CG1222... 40 0.071
UniRef50_UPI00006CB055 Cluster: hypothetical protein TTHERM_0023... 37 0.50
UniRef50_A0V3R8 Cluster: S-layer-like region; n=1; Clostridium c... 36 1.5
UniRef50_A7EYT0 Cluster: Putative uncharacterized protein; n=1; ... 35 2.0
UniRef50_A2STG1 Cluster: Putative anti-sigma regulatory factor, ... 35 2.0
UniRef50_Q9RHY8 Cluster: ORF1 protein; n=1; Corynebacterium ammo... 35 2.7
UniRef50_Q4CYW8 Cluster: Putative uncharacterized protein; n=3; ... 35 2.7
UniRef50_A5NL17 Cluster: ATP-dependent Clp protease, ATP-binding... 34 3.5
UniRef50_Q8EYH8 Cluster: MutS-like mismatch repair protein, ATPa... 33 6.2
UniRef50_Q2AHN9 Cluster: Radical SAM; n=1; Halothermothrix oreni... 33 6.2
UniRef50_Q6IKV8 Cluster: HDC11342; n=2; Drosophila melanogaster|... 33 6.2
UniRef50_Q3EBL2 Cluster: Uncharacterized protein At2g37440.1; n=... 33 8.2
UniRef50_A5BAI3 Cluster: Putative uncharacterized protein; n=2; ... 33 8.2
UniRef50_Q5JCZ5 Cluster: Putative uncharacterized protein; n=2; ... 33 8.2
>UniRef50_UPI0000D5551D Cluster: PREDICTED: similar to Pyruvate
kinase (PK); n=1; Tribolium castaneum|Rep: PREDICTED:
similar to Pyruvate kinase (PK) - Tribolium castaneum
Length = 557
Score = 299 bits (733), Expect = 7e-80
Identities = 139/223 (62%), Positives = 171/223 (76%)
Frame = +2
Query: 104 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 283
+QL H LDI S +RL+GIICT+GP++ +V LE+M+E GMN+AR+ SHG+ E H
Sbjct: 32 TQLDHNSLLDIQSHPPQVRLTGIICTLGPSTTDVETLERMIEAGMNIARLTLSHGTQEMH 91
Query: 284 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 463
E I+N R A ++YS +LG + L++ALD KGPE+RTG +EGG +AEVELKKGE IKLTT
Sbjct: 92 TELIQNVRTAVENYSKRLGVMYPLSLALDIKGPEVRTGYMEGGIAAEVELKKGEQIKLTT 151
Query: 464 SSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLG 643
Y EKG++ IYVDY NI VV+PGNRIF+DDGLIS+IC SV LTC++ENGGMLG
Sbjct: 152 DKAYLEKGSSSVIYVDYDNIQKVVQPGNRIFLDDGLISLICTSVQGSVLTCSVENGGMLG 211
Query: 644 SRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRN 772
S K VNLPGI +DLP VSEKDK DLLFGVE G+D + ASFIRN
Sbjct: 212 SCKNVNLPGIDIDLPVVSEKDKEDLLFGVEHGIDTVHASFIRN 254
>UniRef50_Q4SVB7 Cluster: Pyruvate kinase; n=1; Tetraodon
nigroviridis|Rep: Pyruvate kinase - Tetraodon
nigroviridis (Green puffer)
Length = 569
Score = 286 bits (701), Expect = 5e-76
Identities = 140/233 (60%), Positives = 176/233 (75%), Gaps = 7/233 (3%)
Frame = +2
Query: 110 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 289
L+HMC LDIDS + R +GIICTIGPASR+V +L++M+++GMN+AR+NFSHG+HEYHAE
Sbjct: 25 LEHMCLLDIDSAPTTARNTGIICTIGPASRSVGMLKEMIKSGMNIARLNFSHGTHEYHAE 84
Query: 290 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 469
TI+N REA +S+ + IALDTKGPEIRTGL+ G G+AEVELKKG IK+T
Sbjct: 85 TIKNVREACESFEPGSIQYRPIGIALDTKGPEIRTGLIHGSGTAEVELKKGNVIKITLDD 144
Query: 470 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSV-------SADTLTCTIEN 628
Y EK + + +++DYKNIT VV G++I+IDDGLIS+ + + +D L C IEN
Sbjct: 145 AYVEKCSEEILWLDYKNITKVVDVGSKIYIDDGLISLQVKEIGNSSISSGSDYLMCEIEN 204
Query: 629 GGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALH 787
GG LGS+KGVNLPG VDLPAVS+KD DL FGVEQGVDM+FASFIR A +H
Sbjct: 205 GGTLGSKKGVNLPGAAVDLPAVSDKDVKDLQFGVEQGVDMVFASFIRKAADVH 257
>UniRef50_P30613 Cluster: Pyruvate kinase isozymes R/L; n=167;
Fungi/Metazoa group|Rep: Pyruvate kinase isozymes R/L -
Homo sapiens (Human)
Length = 574
Score = 272 bits (667), Expect = 7e-72
Identities = 131/226 (57%), Positives = 171/226 (75%), Gaps = 3/226 (1%)
Frame = +2
Query: 110 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 289
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 70 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 129
Query: 290 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 460
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 130 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 186
Query: 461 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 640
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L
Sbjct: 187 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 246
Query: 641 GSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGA 778
GSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R +
Sbjct: 247 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKAS 292
>UniRef50_Q9VD23 Cluster: Pyruvate kinase; n=5; Coelomata|Rep:
Pyruvate kinase - Drosophila melanogaster (Fruit fly)
Length = 744
Score = 239 bits (584), Expect = 7e-62
Identities = 111/184 (60%), Positives = 137/184 (74%), Gaps = 1/184 (0%)
Frame = +2
Query: 236 MNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGG 415
M V RMNFSHGSHEYH +TI+ R+A Y + G P +LAIALDTKGPEIRTG L GG
Sbjct: 1 MRVVRMNFSHGSHEYHCQTIQAARKAIAMYVEQTGLPRTLAIALDTKGPEIRTGKLAGGN 60
Query: 416 S-AEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQS 592
AE+ELK G+ + L+T + +K N D IYVDY+ + +VKPGNR+F+DDGLI++I +
Sbjct: 61 DRAEIELKTGDKVTLSTKKEMADKSNKDNIYVDYQRLPQLVKPGNRVFVDDGLIALIVKE 120
Query: 593 VSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRN 772
D + C +ENGG LGS KG+NLPG+PVDLP+V+EKDK DL FG EQ VDMIFASFIR+
Sbjct: 121 SKGDEVICQVENGGKLGSHKGINLPGVPVDLPSVTEKDKQDLKFGAEQKVDMIFASFIRD 180
Query: 773 GAAL 784
AL
Sbjct: 181 ANAL 184
>UniRef50_Q27686 Cluster: Pyruvate kinase; n=16; Kinetoplastida|Rep:
Pyruvate kinase - Leishmania mexicana
Length = 499
Score = 229 bits (561), Expect = 5e-59
Identities = 118/224 (52%), Positives = 157/224 (70%), Gaps = 1/224 (0%)
Frame = +2
Query: 104 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 283
SQL H L I + R + IICTIGP++++V L+ ++++GM+VARMNFSHGSHEYH
Sbjct: 2 SQLAHNLTLSIFDPVANYRAARIICTIGPSTQSVEALKGLIQSGMSVARMNFSHGSHEYH 61
Query: 284 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 463
TI N R+A +A+LG ++AIALDTKGPEIRTG GG + +++G T +TT
Sbjct: 62 QTTINNVRQA----AAELG--VNIAIALDTKGPEIRTGQFVGGDAV---MERGATCYVTT 112
Query: 464 SSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSAD-TLTCTIENGGML 640
+ +KG D Y+DY+N++ VV+PGN I+IDDG++ + QS + TL CT+ N +
Sbjct: 113 DPAFADKGTKDKFYIDYQNLSKVVRPGNYIYIDDGILILQVQSHEDEQTLECTVTNSHTI 172
Query: 641 GSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRN 772
R+GVNLPG VDLPAVS KD+ DL FGVEQGVDMIFASFIR+
Sbjct: 173 SDRRGVNLPGCDVDLPAVSAKDRVDLQFGVEQGVDMIFASFIRS 216
>UniRef50_Q7RVA8 Cluster: Pyruvate kinase; n=11; Ascomycota|Rep:
Pyruvate kinase - Neurospora crassa
Length = 527
Score = 206 bits (503), Expect = 5e-52
Identities = 104/229 (45%), Positives = 149/229 (65%), Gaps = 2/229 (0%)
Frame = +2
Query: 95 NVGSQLQHMCGLDIDSKSSY-IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGS 271
++G ++Q + L+ + + + R + IICTIGP + +V + K+ + G+NV RMNFSHGS
Sbjct: 10 SLGGKIQWLAQLNTEFQPAREFRRTSIICTIGPKTNSVEAINKLRDAGLNVVRMNFSHGS 69
Query: 272 HEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETI 451
+EYH I N R+AEK + G P +AIALDTKGPEIRTG + ++ + G +
Sbjct: 70 YEYHQSVIDNARQAEKVHP---GRP--IAIALDTKGPEIRTGNTKN--DEDIPISAGTIL 122
Query: 452 KLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIEN 628
+TT Y+++ + +YVDY NIT V+ PG I++DDG+++ + + V T+ N
Sbjct: 123 NITTDEKYKDECTIEHMYVDYVNITKVIAPGRIIYVDDGVLAFEVLEIVDDKTIKVKARN 182
Query: 629 GGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNG 775
G + SRKGVNLP VDLPA+SEKDK+DL FGV+ VDM+FASFIR G
Sbjct: 183 NGYISSRKGVNLPNTDVDLPALSEKDKADLRFGVKNKVDMVFASFIRRG 231
>UniRef50_Q9VQH0 Cluster: Pyruvate kinase; n=3; Sophophora|Rep:
Pyruvate kinase - Drosophila melanogaster (Fruit fly)
Length = 554
Score = 199 bits (486), Expect = 6e-50
Identities = 98/231 (42%), Positives = 146/231 (63%)
Frame = +2
Query: 80 KPTVANVGSQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNF 259
K + +QL H+C LD+ ++S+ RL +I TI +SRN + M+ G+N+ R+NF
Sbjct: 6 KSVLKEGSTQLSHICELDLAQQASHQRLVSLIATISVSSRNADTIYTMIMRGVNIFRLNF 65
Query: 260 SHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKK 439
SH SHE H++TI EA + + G ++AIA DT+GP+IRTGLL+G +V L+
Sbjct: 66 SHESHEMHSKTIELINEALERIHKETGQIRTVAIAADTRGPQIRTGLLDG----DVFLRS 121
Query: 440 GETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCT 619
G+ ++L+ + D +KGN + +YVDY NI N+ K G+R+FIDDG + + V D L C
Sbjct: 122 GDNLRLSINRDLYDKGNKEAVYVDYPNIINLTKTGDRLFIDDGRLLLHILEVGVDGLLCE 181
Query: 620 IENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRN 772
+ +GG L + V LP I +DLPAVSEKD D+ F ++ VD +FAS +R+
Sbjct: 182 VIHGGQLNNNCNVILPEIEIDLPAVSEKDMFDIQFSIKANVDFLFASAVRS 232
>UniRef50_Q42806 Cluster: Pyruvate kinase, cytosolic isozyme; n=62;
Eukaryota|Rep: Pyruvate kinase, cytosolic isozyme -
Glycine max (Soybean)
Length = 511
Score = 189 bits (460), Expect = 8e-47
Identities = 98/208 (47%), Positives = 134/208 (64%), Gaps = 3/208 (1%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
I+CT+GPASR+V + EK++ GMNVAR NFSHG+H+YH ET+ N + +A +
Sbjct: 25 IVCTLGPASRSVEMTEKLLRAGMNVARFNFSHGTHDYHQETLNNLK------TAMHNTGI 78
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
A+ LDTKGPEIRTG L+ G ++LK+G+ + +TT DY KG+ + I + YK +
Sbjct: 79 LCAVMLDTKGPEIRTGFLKDG--KPIQLKEGQEVTITT--DYDIKGDPEMISMSYKKLPV 134
Query: 530 VVKPGNRIFIDDGLISIICQSVSAD--TLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEK 703
+KPGN I DG I++ S D T+ C EN LG RK VNLPG+ VDLP ++EK
Sbjct: 135 HLKPGNTILCSDGTITLTVLSCDPDAGTVRCRCENTATLGERKNVNLPGVVVDLPTLTEK 194
Query: 704 DKSDLL-FGVEQGVDMIFASFIRNGAAL 784
DK D+L +GV +DMI SF+R G+ L
Sbjct: 195 DKEDILGWGVPNKIDMIALSFVRKGSDL 222
>UniRef50_P77983 Cluster: Pyruvate kinase I; n=29; Bacteria|Rep:
Pyruvate kinase I - Salmonella typhimurium
Length = 470
Score = 183 bits (445), Expect = 5e-45
Identities = 94/200 (47%), Positives = 126/200 (63%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
I+CTIGP + + +L KM++ GMNV R+NFSHG + H + I+N R +K G
Sbjct: 6 IVCTIGPKTESEEMLSKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNV----MSKTGK-- 59
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
AI LDTKGPEIRT LEGG +V LK G+T TT D GN + + V Y+ T+
Sbjct: 60 KAAILLDTKGPEIRTIKLEGGN--DVSLKAGQTFTFTT--DKSVVGNNEIVAVTYEGFTS 115
Query: 530 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 709
+ GN + +DDGLI + ++ + + C + N G LG KGVNLPG+ + LPA++EKDK
Sbjct: 116 DLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALAEKDK 175
Query: 710 SDLLFGVEQGVDMIFASFIR 769
DL+FG EQGVD + ASFIR
Sbjct: 176 QDLIFGCEQGVDFVAASFIR 195
>UniRef50_Q9M057 Cluster: Pyruvate kinase; n=11; Magnoliophyta|Rep:
Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress)
Length = 510
Score = 182 bits (442), Expect = 1e-44
Identities = 97/208 (46%), Positives = 134/208 (64%), Gaps = 3/208 (1%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
IICT+GP SR+V ++EK+++ GMNVAR NFSHGSH YH ET+ N R A + +
Sbjct: 20 IICTLGPVSRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDN------TGI 73
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
A+ LDTKGPEIRTG L+ G ++L +G+ ++T S DY +G+++ I + YK +
Sbjct: 74 LSAVMLDTKGPEIRTGFLKEG--KPIQLNQGQ--EITISIDYMIEGDSNVISMSYKKLAE 129
Query: 530 VVKPGNRIFIDDGLISIICQSV--SADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEK 703
VKPG+ I DG IS+ S S + C EN +LG RK VNLPGI VDLP ++EK
Sbjct: 130 DVKPGDVILCSDGTISLTVLSCDKSFGLVRCRCENSAILGERKNVNLPGIVVDLPTLTEK 189
Query: 704 DKSDLL-FGVEQGVDMIFASFIRNGAAL 784
DK D++ +GV +D+I SF+R G+ L
Sbjct: 190 DKEDIIQWGVPNKIDIIALSFVRKGSDL 217
>UniRef50_A4E9R2 Cluster: Pyruvate kinase; n=1; Collinsella
aerofaciens ATCC 25986|Rep: Pyruvate kinase -
Collinsella aerofaciens ATCC 25986
Length = 486
Score = 179 bits (435), Expect = 8e-44
Identities = 91/208 (43%), Positives = 137/208 (65%), Gaps = 3/208 (1%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
I+CT+GPA + + +M++ GMNVAR NFSHGS++ H I R K +LG P
Sbjct: 7 IVCTMGPACDSDETIREMIKAGMNVARFNFSHGSYDEHHGRIERVRRISK----ELGLP- 61
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT---TSSDYQEKGNADTIYVDYKN 520
+ I LDTKGPE+RTGLL G +V +K G+ I +T TS D+ G A+ I +DY
Sbjct: 62 -VGILLDTKGPEVRTGLLVDG--KKVAVKTGDKIVVTAQPTSEDFH--GTAEHISLDYLA 116
Query: 521 ITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 700
+ + V+ G+ I IDDGL+++ +SV +TC ++N G++G RKGVN+P + + LPA++E
Sbjct: 117 LPSEVEKGSLILIDDGLVALEVESVDGQDMTCVVKNDGLIGERKGVNMPNVNISLPAITE 176
Query: 701 KDKSDLLFGVEQGVDMIFASFIRNGAAL 784
+D+ D+LFG+ + +D I ASFIR+G ++
Sbjct: 177 RDRQDILFGLTENIDYIAASFIRDGESV 204
>UniRef50_P80885 Cluster: Pyruvate kinase; n=161; Bacteria|Rep:
Pyruvate kinase - Bacillus subtilis
Length = 585
Score = 177 bits (432), Expect = 2e-43
Identities = 98/207 (47%), Positives = 135/207 (65%), Gaps = 2/207 (0%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
+R + I+CTIGPAS ++ +L K+ME+GMNVAR+NFSHG E H I+N REA K K
Sbjct: 1 MRKTKIVCTIGPASESIEMLTKLMESGMNVARLNFSHGDFEEHGARIKNIREASK----K 56
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
LG ++ I LDTKGPEIRT +E GG +EL+ G+ +L S D + G D I V Y
Sbjct: 57 LGK--NVGILLDTKGPEIRTHTMENGG---IELETGK--ELIISMD-EVVGTTDKISVTY 108
Query: 515 KNITNVVKPGNRIFIDDGLISIICQSVSA--DTLTCTIENGGMLGSRKGVNLPGIPVDLP 688
+ + + V+ G+ I +DDGLI + V A + + N G L ++KGVN+PG+ V+LP
Sbjct: 109 EGLVHDVEQGSTILLDDGLIGLEVLDVDAAKREIKTKVLNNGTLKNKKGVNVPGVSVNLP 168
Query: 689 AVSEKDKSDLLFGVEQGVDMIFASFIR 769
++EKD D++FG+EQGVD I SFIR
Sbjct: 169 GITEKDARDIVFGIEQGVDFIAPSFIR 195
>UniRef50_Q8EX62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep:
Pyruvate kinase - Leptospira interrogans
Length = 486
Score = 177 bits (431), Expect = 3e-43
Identities = 90/211 (42%), Positives = 138/211 (65%)
Frame = +2
Query: 140 SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEK 319
S+SS R + IICTIGPA+ + +++ + E GMNVAR+N SHG+H++H IRN + K
Sbjct: 3 SESSVFRKTKIICTIGPATSDKKMIQALAEAGMNVARLNMSHGNHDFHRSIIRNIKSLNK 62
Query: 320 SYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADT 499
L +P +AI LDT+GPEIRTG L+ ++LK GET E+ +
Sbjct: 63 DV---LKNP--IAILLDTQGPEIRTGDLQVD---HLDLKVGETFTFHIIPG--EESEEQS 112
Query: 500 IYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPV 679
++V+YK+I +K G+ + +D+GLI+++ + ++ L C + +GG LGSRK +NLPGI V
Sbjct: 113 VFVNYKDIVKDLKVGDPVTVDNGLINLVVEEINDSALKCKVLDGGRLGSRKHINLPGIRV 172
Query: 680 DLPAVSEKDKSDLLFGVEQGVDMIFASFIRN 772
+LP+++ KD D+LFG+E+ VD I SF+R+
Sbjct: 173 NLPSITPKDHKDILFGLEEDVDFIALSFVRS 203
>UniRef50_Q9KUN0 Cluster: Pyruvate kinase; n=24; cellular
organisms|Rep: Pyruvate kinase - Vibrio cholerae
Length = 470
Score = 173 bits (420), Expect = 6e-42
Identities = 93/203 (45%), Positives = 123/203 (60%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
I+CTIGP + +V L +++ GMNV R+NFSHG + H I N R+ + +L
Sbjct: 6 IVCTIGPKTESVEKLTELVNAGMNVMRLNFSHGDYVEHGTRITNFRKVMEVTGKQL---- 61
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
AI LDTKGPEIRT LE G +V+L G+ TT D + GN + + V Y
Sbjct: 62 --AILLDTKGPEIRTIKLENGD--DVDLVAGQEFTFTT--DTKVVGNKERVAVTYSGFAK 115
Query: 530 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 709
+ GNRI +DDGLI + + + + C + N G LG KGVNLPG+ V+LPA+SEKDK
Sbjct: 116 DLNVGNRILVDDGLIEMEVLATTDTEVKCKVLNNGALGENKGVNLPGVSVNLPALSEKDK 175
Query: 710 SDLLFGVEQGVDMIFASFIRNGA 778
+DL FG EQGVD + ASFIR G+
Sbjct: 176 NDLKFGCEQGVDFVAASFIRKGS 198
>UniRef50_O44006 Cluster: Pyruvate kinase; n=10; cellular
organisms|Rep: Pyruvate kinase - Eimeria tenella
Length = 531
Score = 170 bits (413), Expect = 4e-41
Identities = 85/202 (42%), Positives = 126/202 (62%), Gaps = 1/202 (0%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
I+CT+GP+ +V + ++++ GMNV R+NFSHG HE H ++N +EA K K
Sbjct: 60 IVCTMGPSCWDVDKMVQLIDAGMNVCRLNFSHGDHEAHGRVVKNLQEALKQRPGK----- 114
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
+A+ LDTKGPEIRTG+LEG +EL G+ +K+ T DY GN I Y+ + +
Sbjct: 115 RVALLLDTKGPEIRTGMLEG--DKPIELHAGDMLKIVT--DYSFVGNKSCIACSYEKLPS 170
Query: 530 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 709
VKPGN I I DG +S+ D + + N ++G++K +NLPG+ VDLP + EKDK
Sbjct: 171 SVKPGNTILIADGSLSVEVVECGKDYVMTRVMNPAIIGNKKNMNLPGVKVDLPVIGEKDK 230
Query: 710 SDLL-FGVEQGVDMIFASFIRN 772
+D+L FG+ G + I ASF+++
Sbjct: 231 NDILNFGIPMGCNFIAASFVQS 252
>UniRef50_P52489 Cluster: Pyruvate kinase 2; n=33; Dikarya|Rep:
Pyruvate kinase 2 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 506
Score = 169 bits (411), Expect = 7e-41
Identities = 89/223 (39%), Positives = 129/223 (57%), Gaps = 1/223 (0%)
Frame = +2
Query: 104 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 283
S+LQ + L I + +R + II TIGP + + + + + G+N+ R+NFSHGS+E+H
Sbjct: 4 SRLQRLANLKIGTPQQ-LRRTSIIGTIGPKTNSCEAITALRKAGLNIIRLNFSHGSYEFH 62
Query: 284 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 463
I N ++E+ + G P LAIALDTKGPEIRTG ++ + + TT
Sbjct: 63 QSVIENAVKSEQQFP---GRP--LAIALDTKGPEIRTGRTLN--DQDLYIPVDHQMIFTT 115
Query: 464 SSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGML 640
+ + N +Y+DY N+T V+ PG I++DDG++S + Q + L N G +
Sbjct: 116 DASFANTSNDKIMYIDYANLTKVIVPGRFIYVDDGILSFKVLQIIDESNLRVQAVNSGYI 175
Query: 641 GSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIR 769
S KGVNLP VDLP +S KD DL FGV G+ ++FASFIR
Sbjct: 176 ASHKGVNLPNTDVDLPPLSAKDMKDLQFGVRNGIHIVFASFIR 218
>UniRef50_Q2TSW8 Cluster: Pyruvate kinase; n=4; stramenopiles|Rep:
Pyruvate kinase - Phaeodactylum tricornutum
Length = 543
Score = 168 bits (409), Expect = 1e-40
Identities = 91/207 (43%), Positives = 128/207 (61%), Gaps = 3/207 (1%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
R + I+CTIGPA NV LE ++E+GMNVAR NFSHG H H + R+A ++
Sbjct: 31 RRTKIVCTIGPACWNVDQLEILIESGMNVARFNFSHGDHAGHGAVLERVRQAAQNKGR-- 88
Query: 338 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 517
++AI LDTKGPEIRTG G S ++EL KGETI LT SDY+ KG+ + Y
Sbjct: 89 ----NIAILLDTKGPEIRTGFFANGAS-KIELVKGETIVLT--SDYKFKGDQHKLACSYP 141
Query: 518 NITNVVKPGNRIFIDDG--LISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPA 691
+ V G +I + DG +++++ +A ++C I+N +G RK +NLPG+ VDLP
Sbjct: 142 ALAQSVTQGQQILVADGSLVLTVLQTDEAAGEVSCRIDNNASMGERKNMNLPGVKVDLPT 201
Query: 692 VSEKDKSDLL-FGVEQGVDMIFASFIR 769
+EKD D++ FG++ VD I ASF+R
Sbjct: 202 FTEKDVDDIVNFGIKHKVDFIAASFVR 228
>UniRef50_Q1FK29 Cluster: Pyruvate kinase; n=4; Clostridiales|Rep:
Pyruvate kinase - Clostridium phytofermentans ISDg
Length = 580
Score = 167 bits (407), Expect = 2e-40
Identities = 87/205 (42%), Positives = 127/205 (61%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
+R + I+CT+GPA+ + AVL ++M GM+VAR NFSHG +E H R SA+
Sbjct: 1 MRKTKIVCTLGPATEDDAVLRQLMIEGMDVARFNFSHGDYEQHTRNYERIRRL----SAE 56
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
L P +A LDTKGPEIR G E G ++ELKKG+ LTT+ G+ + + Y
Sbjct: 57 LKLP--IATLLDTKGPEIRIGTFENG---KIELKKGQIFTLTTNDIV---GDETQVSITY 108
Query: 515 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 694
KN+ +K G +I IDDGLI + +++ + C + NGGM+ + KGVN+PG+ + +P +
Sbjct: 109 KNLIRDIKNGVKILIDDGLIELKVFNITDTDIICEVLNGGMISNHKGVNVPGVELSMPFI 168
Query: 695 SEKDKSDLLFGVEQGVDMIFASFIR 769
S++D D++FG+ QG D I ASF R
Sbjct: 169 SKRDYEDIVFGIGQGFDFIAASFTR 193
>UniRef50_Q2TSW6 Cluster: Pyruvate kinase; n=1; Achlya
bisexualis|Rep: Pyruvate kinase - Achlya bisexualis
(Water mold)
Length = 517
Score = 166 bits (404), Expect = 5e-40
Identities = 84/213 (39%), Positives = 130/213 (61%), Gaps = 3/213 (1%)
Frame = +2
Query: 140 SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEK 319
SK+ ++ I+ T+GP S N +++ G+ + R+NFSH +++ + + R ++
Sbjct: 23 SKNDAFSMTKIVGTVGPVSENAKTTQELTNAGLKIMRINFSHATYDEAHLRMSHLRASKG 82
Query: 320 SYSAKLGSPFSL-AIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNAD 496
++ G F++ A+ LDT+GPEIR G ++ L KG+ I LTT Y+E D
Sbjct: 83 VHAKHTGKEFNVRAVLLDTQGPEIRGGAFP---EKKINLTKGDMITLTTDVQYKEASTKD 139
Query: 497 TIYVDYKNITNVVKPGNRIFIDDGLISIICQS--VSADTLTCTIENGGMLGSRKGVNLPG 670
+YV Y+ + VK G+ + +DDGLIS+ +S V++ + C IEN +LGSRKGVNLPG
Sbjct: 140 MLYVTYEQLPATVKVGDTVLLDDGLISLTVKSIDVASGQVRCLIENSEVLGSRKGVNLPG 199
Query: 671 IPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIR 769
+ VDLPA++ KDK D+ FGVE +D I SF+R
Sbjct: 200 LVVDLPALTAKDKQDVEFGVEHDMDFIAVSFVR 232
>UniRef50_Q55863 Cluster: Pyruvate kinase 1; n=5; Cyanobacteria|Rep:
Pyruvate kinase 1 - Synechocystis sp. (strain PCC 6803)
Length = 483
Score = 165 bits (400), Expect = 1e-39
Identities = 86/206 (41%), Positives = 127/206 (61%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
I+ TIGPAS +V V+ +M++ GMNVAR+NFSHGS+E HA +R R E+ ++ +P
Sbjct: 20 IVATIGPASSSVEVIRQMVDAGMNVARLNFSHGSYEDHATMVRLLRSVEQ----EMDTPI 75
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
+L D +GP+IR G L GG E +L++GE + L A + +DY ++
Sbjct: 76 TLL--QDLQGPKIRIGQLPGG---EKQLREGEKVSLVPVEIGDRHPGA--VGIDYPHLAT 128
Query: 530 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 709
K G RI +DDGL+ + S+ + C + GG+L SRKGVNLPG+ + LP+++ KDK
Sbjct: 129 EAKVGERILLDDGLLEMKVVSIQDPEVICEVVTGGILKSRKGVNLPGLVLTLPSMTTKDK 188
Query: 710 SDLLFGVEQGVDMIFASFIRNGAALH 787
DL FG+ QG+D + SF+R G +H
Sbjct: 189 QDLEFGLSQGIDWVSLSFVRKGEDIH 214
>UniRef50_Q22Z06 Cluster: Pyruvate kinase family protein; n=3;
Oligohymenophorea|Rep: Pyruvate kinase family protein -
Tetrahymena thermophila SB210
Length = 505
Score = 159 bits (387), Expect = 6e-38
Identities = 82/205 (40%), Positives = 124/205 (60%), Gaps = 1/205 (0%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
R + I+CTIGP+ + L +++E GMNVAR+NFSHG H H ET+R +EA K+
Sbjct: 22 RKTKIVCTIGPSCWDHDNLVQLLENGMNVARLNFSHGDHAGHGETVRRLKEAFKARKN-- 79
Query: 338 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 517
A+ LDTKGPEIRTGL++ + L G+ +++TT DY G+ + YK
Sbjct: 80 ---IQCALMLDTKGPEIRTGLVKDQTKKLINLVAGQELEITT--DYSVLGDEKVLACSYK 134
Query: 518 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 697
++ VK G ++ I DG + I + + D++ ++N +G +K +NLPG VDLP V+
Sbjct: 135 SLPKSVKVGGQVLIADGTLVCIVKEIKQDSIIVNVQNTCSIGEKKNMNLPGAIVDLPTVT 194
Query: 698 EKDKSDLL-FGVEQGVDMIFASFIR 769
EKD+ D++ FG++ G+D I SF R
Sbjct: 195 EKDEDDIVNFGLKHGIDCIALSFAR 219
>UniRef50_Q090R5 Cluster: Pyruvate kinase; n=1; Stigmatella
aurantiaca DW4/3-1|Rep: Pyruvate kinase - Stigmatella
aurantiaca DW4/3-1
Length = 515
Score = 159 bits (385), Expect = 1e-37
Identities = 87/209 (41%), Positives = 128/209 (61%), Gaps = 1/209 (0%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
+R + I+CT+GPAS++ +LE ++E GM+VAR+NFSHGSHE HAE I R A S K
Sbjct: 10 MRRAKIVCTLGPASQSQDMLEALIEAGMDVARLNFSHGSHEQHAENIAKLRAA----SLK 65
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
L ++ I D +GP+IRTG G + LK+G +TT D KGN D + Y
Sbjct: 66 LRK--AVGILGDLQGPKIRTGRFITGSTV---LKEGAIFSITT--DESVKGNDDIVSTTY 118
Query: 515 KNITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPA 691
++ V PG+RI +DDGL+ + + ++ L + GG L + KG+NLPG+ V A
Sbjct: 119 AHLAADVNPGDRILLDDGLLELKVLETDKKQLLRTQVVIGGTLKNNKGINLPGVAVRADA 178
Query: 692 VSEKDKSDLLFGVEQGVDMIFASFIRNGA 778
++ KD+ DL+FG+++GVD + SF+R A
Sbjct: 179 LTPKDREDLVFGIKEGVDFLALSFVRQPA 207
>UniRef50_Q747D6 Cluster: Pyruvate kinase; n=6;
Desulfuromonadales|Rep: Pyruvate kinase - Geobacter
sulfurreducens
Length = 480
Score = 157 bits (381), Expect = 3e-37
Identities = 87/207 (42%), Positives = 126/207 (60%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
R + II T+GP S + ++ ++M+ G++V R+NFSHGS++ E I R SA+
Sbjct: 6 RKTKIIATLGPVSSSPDMIRQLMDAGVDVFRLNFSHGSNDQRREVIAAIRRL----SAER 61
Query: 338 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 517
G + I D +GP+IRTG +E G + L +G+++ +TT G TIY +
Sbjct: 62 GK--EIGILADLQGPKIRTGRMENGA---IPLVRGDSLDITTDEVLGRPGLISTIY---Q 113
Query: 518 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 697
++ + VKPG+RI +DDGLI + QSVS T+ CT+ GGML KG+NLPG+ V P++S
Sbjct: 114 SLPHDVKPGSRILLDDGLIELRVQSVSGATVRCTVVQGGMLKDLKGINLPGVKVSAPSLS 173
Query: 698 EKDKSDLLFGVEQGVDMIFASFIRNGA 778
EKD DL F +E GVD I SF+R A
Sbjct: 174 EKDLRDLDFCLEVGVDYIALSFVRTAA 200
>UniRef50_Q1K4D5 Cluster: Pyruvate kinase; n=1; Desulfuromonas
acetoxidans DSM 684|Rep: Pyruvate kinase -
Desulfuromonas acetoxidans DSM 684
Length = 474
Score = 154 bits (373), Expect = 3e-36
Identities = 82/205 (40%), Positives = 127/205 (61%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
+R + I+CT+GPAS + A LE+M+ +GMNVAR+NFSHG H+ H + I R K +
Sbjct: 1 MRRTKIVCTVGPASADEATLEQMISSGMNVARLNFSHGDHDSHQQLIERIRAVAK----R 56
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
L P +AI D GP+IR G L G V L +G+ + L ++ + G D + VDY
Sbjct: 57 LNQP--VAILQDLCGPKIRLGQLPEQG---VRLHQGDAVSLCSTG---QAGEGD-LPVDY 107
Query: 515 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 694
++ V+ G+ I + DGL+ + + + A + C++ +GG+ SRKGVN+P + +PA
Sbjct: 108 PSLHEDVQVGDSIMLSDGLMELQVERIDAPQVQCSVISGGVAYSRKGVNMPSSHLSIPAF 167
Query: 695 SEKDKSDLLFGVEQGVDMIFASFIR 769
+EKD+ DL FG++QGVD++ SF+R
Sbjct: 168 TEKDRDDLRFGLQQGVDIVALSFVR 192
>UniRef50_Q46078 Cluster: Pyruvate kinase; n=19; Actinobacteria
(class)|Rep: Pyruvate kinase - Corynebacterium
glutamicum (Brevibacterium flavum)
Length = 475
Score = 154 bits (373), Expect = 3e-36
Identities = 78/207 (37%), Positives = 121/207 (58%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
R + I+CT+GPA + + +++E GM+VAR+NFSHG H H + + REA + +
Sbjct: 3 RRTKIVCTLGPAVASADGILRLVEDGMDVARLNFSHGDHPDHEQNYKWVREAAEKTGRAV 62
Query: 338 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 517
G I D +GP+IR G G + + GETI++T +G D + YK
Sbjct: 63 G------ILADLQGPKIRLGRFTDGATV---WENGETIRITVDD---VEGTHDRVSTTYK 110
Query: 518 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 697
N+ KPG+R+ +DDG + ++C SV + + C + GG + + KGV+LPG+ + +PA+S
Sbjct: 111 NLAKDAKPGDRLLVDDGKVGLVCVSVEGNDVICEVVEGGPVSNNKGVSLPGMDISVPALS 170
Query: 698 EKDKSDLLFGVEQGVDMIFASFIRNGA 778
EKD DL F ++ GVD I SF+R+ A
Sbjct: 171 EKDIRDLRFALKLGVDFIALSFVRSPA 197
>UniRef50_A7HIL5 Cluster: Pyruvate kinase; n=9; Bacteria|Rep:
Pyruvate kinase - Anaeromyxobacter sp. Fw109-5
Length = 491
Score = 153 bits (371), Expect = 5e-36
Identities = 80/206 (38%), Positives = 124/206 (60%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
+R + I+ T+GPAS + VL++M+ G++VAR+NFSHG HE HA+ + R A S
Sbjct: 4 MRRAKIVATLGPASSDPDVLQRMLAAGVDVARLNFSHGRHEDHAQMLDRIRTA----SRH 59
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
LG ++A+ D +GP+IRTG L G V L+ G + + T D + KG+A + Y
Sbjct: 60 LGR--AVAVLQDLQGPKIRTGPLAAGREG-VRLEAGAELVIAT--DAEVKGDAKLVSTTY 114
Query: 515 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 694
++ V+PG+R+ +DDGLI + C + GG+L KG+NLPG+ + A+
Sbjct: 115 PHLAEDVRPGDRLLVDDGLIELRVLETDGVRARCQVVEGGVLREHKGINLPGVALRAEAL 174
Query: 695 SEKDKSDLLFGVEQGVDMIFASFIRN 772
SEKD++D+ FG+ GVD + SF+R+
Sbjct: 175 SEKDRADIAFGLAHGVDAVALSFVRS 200
>UniRef50_Q08SK3 Cluster: Pyruvate kinase; n=2;
Cystobacterineae|Rep: Pyruvate kinase - Stigmatella
aurantiaca DW4/3-1
Length = 481
Score = 151 bits (367), Expect = 1e-35
Identities = 83/211 (39%), Positives = 123/211 (58%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
+R + IICT+GPAS V+E ++ GMNVAR+NFSHG +E H + R+ S K
Sbjct: 16 MRKAKIICTLGPASDTPEVIEGLVRAGMNVARINFSHGVYEDHRRRVNTLRKV----SRK 71
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
LG P +AI D +GP+IR G EGG ++ ++ G+T+ +TT + G I
Sbjct: 72 LGIP--VAILQDIQGPKIRLGRFEGG---QLLVQAGQTVTVTTRAVL---GQGTLIPTPV 123
Query: 515 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 694
+++T V G+ I +DDG + + V+ +T T+E GG+L KG+NLPG + +P +
Sbjct: 124 RSLTRDVTRGDMILLDDGRVRLRVVRVAGRDVTATVEVGGLLKDHKGLNLPGAAISVPTI 183
Query: 695 SEKDKSDLLFGVEQGVDMIFASFIRNGAALH 787
+EKD DL FG E GVD + SF+R +H
Sbjct: 184 TEKDAEDLAFGQELGVDYVALSFVRTANDIH 214
>UniRef50_A3I0G9 Cluster: Pyruvate kinase; n=3;
Flexibacteraceae|Rep: Pyruvate kinase - Algoriphagus sp.
PR1
Length = 476
Score = 150 bits (363), Expect = 4e-35
Identities = 81/201 (40%), Positives = 115/201 (57%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
I+ TIGPAS N + + G NV R+NFSHGSH+ H E I R+ K + LG
Sbjct: 11 ILATIGPASNNYETISSLAAAGANVFRLNFSHGSHDIHQEVIEIIRKINKEQNLNLG--- 67
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
I D +GP+IR G +E G VE+K GE K+T ++D G + + Y+N+
Sbjct: 68 ---ILQDLQGPKIRVGEVENNG---VEIKPGE--KITITND-PVVGTSTLVSTVYQNLPQ 118
Query: 530 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 709
V G+RI IDDG + ++ + CT+ +GG+L SRKG+NLP V P+++EKD
Sbjct: 119 DVVSGDRILIDDGNLEVVVNDTDGKNVNCTVIHGGILKSRKGINLPNTKVSAPSLTEKDI 178
Query: 710 SDLLFGVEQGVDMIFASFIRN 772
DL FG+ + VD I SF+R+
Sbjct: 179 EDLAFGLSKEVDWIALSFVRS 199
>UniRef50_Q4U977 Cluster: Pyruvate kinase, putative; n=3;
Piroplasmida|Rep: Pyruvate kinase, putative - Theileria
annulata
Length = 513
Score = 150 bits (363), Expect = 4e-35
Identities = 81/199 (40%), Positives = 118/199 (59%), Gaps = 1/199 (0%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
I+CT+GPA NV + +M+++GMN+ R NFSHG+HE H +T+ +EA KS
Sbjct: 42 IVCTMGPACGNVETIIQMVKSGMNICRFNFSHGNHETHTKTLNLVKEALKSVPEA----- 96
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
++ + LDTKGPEIRTG L+ + L++G T+K+TT DY +G+ I YK +
Sbjct: 97 NIGLMLDTKGPEIRTGFLK--NHTPITLEEGSTLKITT--DYTIEGDETIISCSYKKLPQ 152
Query: 530 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 709
VK GN I I DG +S +V D + + N +G K +NLPG+ V+LP ++E DK
Sbjct: 153 SVKVGNIILIADGSLSCEVLAVFDDYIEVKVLNNAKIGEYKNMNLPGVKVELPVLTESDK 212
Query: 710 SDLL-FGVEQGVDMIFASF 763
+L FG+ +D I SF
Sbjct: 213 DYILNFGIPNQMDFIALSF 231
>UniRef50_Q81N35 Cluster: Pyruvate kinase; n=11; Bacillus cereus
group|Rep: Pyruvate kinase - Bacillus anthracis
Length = 352
Score = 149 bits (360), Expect = 1e-34
Identities = 79/199 (39%), Positives = 117/199 (58%)
Frame = +2
Query: 173 ICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 352
+CTIGPAS N L K++ GM + R+N SHG+HE H + IR + + S
Sbjct: 6 VCTIGPASNNKETLAKLINNGMKIVRLNLSHGTHESHKDIIRLVKSLDDS---------- 55
Query: 353 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 532
+ I D +GP+IR G ++G ++ L+ G++ L T G++ VDY+ I N
Sbjct: 56 IKILGDVQGPKIRLGEIKG---EQITLQAGDSFMLRTQP---VTGSSTEASVDYEGIAND 109
Query: 533 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 712
VK G+RI ++DG + +I + VS D + ++ GG + S KGVNLPG V LPA++EKDK
Sbjct: 110 VKVGSRILMNDGEVELIVEKVSTDKIETKVKTGGNISSHKGVNLPGAIVSLPAITEKDKK 169
Query: 713 DLLFGVEQGVDMIFASFIR 769
D+ F +E+ VD I SF+R
Sbjct: 170 DIQFLLEEDVDFIACSFVR 188
>UniRef50_Q2IHE2 Cluster: Pyruvate kinase; n=1; Anaeromyxobacter
dehalogenans 2CP-C|Rep: Pyruvate kinase -
Anaeromyxobacter dehalogenans (strain 2CP-C)
Length = 489
Score = 148 bits (359), Expect = 1e-34
Identities = 77/205 (37%), Positives = 123/205 (60%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
+R + I+ T+GPAS VL +++E G++VAR+NFSHG HE HA + R A S
Sbjct: 1 MRRAKIVATLGPASGEPDVLARLLEQGVDVARLNFSHGRHEDHARMLDKIRAA----SRH 56
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
LG ++A+ D +GP+IRTG L+ G A V+++ G+ + +TT + G+A + Y
Sbjct: 57 LGK--AVAVLQDLQGPKIRTGPLKAG-KAGVQVEAGQELVITTEGELP--GDAHLVSTTY 111
Query: 515 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 694
++ V+ G+R+ +DDGL+ + + + GG LG KG+NLPG+ + A+
Sbjct: 112 PHLAEDVRAGDRLLVDDGLLEFRVLATDGVRVRTEVVEGGWLGEHKGINLPGVALRAEAL 171
Query: 695 SEKDKSDLLFGVEQGVDMIFASFIR 769
SEKD++D+ FG+ GVD + SF+R
Sbjct: 172 SEKDRADVAFGISHGVDYVALSFVR 196
>UniRef50_Q8PYY4 Cluster: Pyruvate kinase; n=3;
Methanosarcinaceae|Rep: Pyruvate kinase - Methanosarcina
mazei (Methanosarcina frisia)
Length = 477
Score = 146 bits (353), Expect = 7e-34
Identities = 83/201 (41%), Positives = 115/201 (57%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
I+CTIGPAS + ++ K+M GMNVAR+NFSHG E H+ +R R+ + +LG
Sbjct: 10 IVCTIGPASSSEEMIRKLMLAGMNVARINFSHGDFESHSRVVRIIRKV----ADELGR-- 63
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
++AI D GP+IR G LE V L KG I LT GN + I V YK +
Sbjct: 64 TIAILADLPGPKIRIGKLE---KEPVMLHKGNPITLTIDDT---PGNEERIPVSYKQLPE 117
Query: 530 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 709
V PG+ I++ DG I ++C+ V+ + C + GG L S KG+NLPG + L AV+EKD
Sbjct: 118 SVTPGSLIYLSDGFIQLLCKEVTGKDVLCEVLIGGELYSHKGLNLPGAKIFLDAVTEKDF 177
Query: 710 SDLLFGVEQGVDMIFASFIRN 772
L F +E+ +D SF+ N
Sbjct: 178 RILEFALEEDIDTFSISFVEN 198
>UniRef50_O06134 Cluster: Pyruvate kinase; n=29; Bacteria|Rep:
Pyruvate kinase - Mycobacterium tuberculosis
Length = 472
Score = 145 bits (351), Expect = 1e-33
Identities = 73/207 (35%), Positives = 117/207 (56%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
R I+CT+GPA++ ++ ++E GM+VARMNFSHG ++ H R A + +
Sbjct: 3 RRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAV 62
Query: 338 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 517
G + D +GP+IR G G + E GET+++T + +G+ D + YK
Sbjct: 63 G------VLADLQGPKIRLGRFASGATHWAE---GETVRITVGAC---EGSHDRVSTTYK 110
Query: 518 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 697
+ G+R+ +DDG ++++ +V D + CT+ GG + KG++LPG+ V PA+S
Sbjct: 111 RLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALS 170
Query: 698 EKDKSDLLFGVEQGVDMIFASFIRNGA 778
EKD DL F + GVDM+ SF+R+ A
Sbjct: 171 EKDIEDLTFALNLGVDMVALSFVRSPA 197
>UniRef50_Q6MLB5 Cluster: Pyruvate kinase; n=1; Bdellovibrio
bacteriovorus|Rep: Pyruvate kinase - Bdellovibrio
bacteriovorus
Length = 495
Score = 144 bits (349), Expect = 2e-33
Identities = 78/205 (38%), Positives = 118/205 (57%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
R + I+ TIGPA+R+ LEK ++ GMNVAR+NFSHGSHE H + + + R+ K A +
Sbjct: 5 RRAKIVATIGPATRDEKNLEKAIKAGMNVARLNFSHGSHEDHLKVVHSLRKLSKELQAPV 64
Query: 338 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 517
AI D +GP+IR G E G +E+K GE + +TT+ + G + D++
Sbjct: 65 ------AILQDLQGPKIRVGKFENGS---IEIKPGEKLVVTTA---KVLGKPGLVPSDFQ 112
Query: 518 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 697
+ PG RI +DDGL+ + V + + + GG+L RKG+NLPG+ + + ++
Sbjct: 113 ELPLACVPGTRILLDDGLMEVKVLQVRGEEIDVEVVYGGILKDRKGMNLPGVNLPVDCMT 172
Query: 698 EKDKSDLLFGVEQGVDMIFASFIRN 772
KD DL FG+ VD I SF+R+
Sbjct: 173 PKDLEDLQFGIANKVDYIALSFVRH 197
>UniRef50_Q0W8N0 Cluster: Pyruvate kinase; n=7; cellular
organisms|Rep: Pyruvate kinase - Uncultured methanogenic
archaeon RC-I
Length = 583
Score = 144 bits (349), Expect = 2e-33
Identities = 79/205 (38%), Positives = 117/205 (57%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
+R + I+CTIGPA + +LEK+ GMNVAR+N SH HE+ +TI N R ++
Sbjct: 1 MRKTKIVCTIGPACDSQDMLEKLAVAGMNVARLNMSHADHEHTVQTINNIRMVSEA---- 56
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
+G P + I +D +GP+IR G L+ LK G T LTT G++ + V +
Sbjct: 57 IGKP--IGILMDLQGPKIRVGTLQ----QPANLKPGGTFTLTTRD---VPGDSQEVNVPF 107
Query: 515 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 694
K + V G + +DDGLI + +V+ + + GG L S+KG+NLP + +P++
Sbjct: 108 KELPQSVSTGQTLLLDDGLIELKVDAVTETDIRTKVVRGGELKSKKGINLPQSTIRIPSI 167
Query: 695 SEKDKSDLLFGVEQGVDMIFASFIR 769
+EKD DL FG+E VDMI SF+R
Sbjct: 168 TEKDVRDLEFGIEHEVDMIAMSFVR 192
>UniRef50_Q3JCE7 Cluster: Pyruvate kinase; n=1; Nitrosococcus oceani
ATCC 19707|Rep: Pyruvate kinase - Nitrosococcus oceani
(strain ATCC 19707 / NCIMB 11848)
Length = 492
Score = 143 bits (347), Expect = 4e-33
Identities = 82/209 (39%), Positives = 122/209 (58%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
R I+CTIGPASR+ A+L KM+ +GMNVAR+NFSHG+HE H REA + +L
Sbjct: 24 RACRIVCTIGPASRSPAILRKMLLSGMNVARLNFSHGNHESHGRIACEIREAAQ----RL 79
Query: 338 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 517
P +AI D +G ++R G ++ S + L++G+ I L + E ++ I +DY+
Sbjct: 80 MKP--VAILQDLQGHKVRVGKVQHPPS--LSLEEGQEILL----GHGETISSKRIGIDYQ 131
Query: 518 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 697
+I V PG ++F+DD I + S+ L C ++ GG L SRKGV P + P ++
Sbjct: 132 DIIQYVTPGQKVFLDDASIELEVLSIEEKDLHCQVKFGGQLRSRKGVIFPDSQLSFPLLN 191
Query: 698 EKDKSDLLFGVEQGVDMIFASFIRNGAAL 784
EKD +D FGV VDM+ SF+R+ +
Sbjct: 192 EKDATDARFGVFLDVDMVAMSFVRSATEI 220
>UniRef50_Q6A9P1 Cluster: Pyruvate kinase; n=4; Actinomycetales|Rep:
Pyruvate kinase - Propionibacterium acnes
Length = 477
Score = 143 bits (346), Expect = 5e-33
Identities = 74/211 (35%), Positives = 126/211 (59%), Gaps = 3/211 (1%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
+R + I+ T+GPA + ++++ME GMN+AR+N SHG + H E + + +S S +
Sbjct: 1 MRRAKIVNTLGPAVTSHDAMKELMEAGMNIARLNMSHGDYSEHQERL----DLVRSVSKE 56
Query: 335 LGSPFSLAIALDTKGPEIRTGLLE---GGGSAEVELKKGETIKLTTSSDYQEKGNADTIY 505
LG ++A D +GP+IRTGL E G + +++LK G+ +TT GN + +
Sbjct: 57 LG--LNVAALADLQGPKIRTGLFEKAEGESNGKIDLKIGDKFTITTDDIV---GNQERVS 111
Query: 506 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDL 685
+K + KPG+ I IDDG + SVS + + C G +G KG+NLPG+ V +
Sbjct: 112 TTFKGLPQDCKPGDVILIDDGKTVLQVDSVSGNDVNCHCTVAGPVGDHKGINLPGVAVSI 171
Query: 686 PAVSEKDKSDLLFGVEQGVDMIFASFIRNGA 778
PA+++KD+ +L + ++ G+D++ SF+R+G+
Sbjct: 172 PALTKKDEENLRWALKAGIDLVALSFVRHGS 202
>UniRef50_Q8TJ98 Cluster: Pyruvate kinase; n=2; Methanomicrobia|Rep:
Pyruvate kinase - Methanosarcina acetivorans
Length = 489
Score = 142 bits (344), Expect = 9e-33
Identities = 79/199 (39%), Positives = 112/199 (56%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
I+CTIGPAS + VL K++ GMNVAR+NFSHG E H + IR R+ +
Sbjct: 22 IVCTIGPASFSEEVLRKLVLAGMNVARINFSHGDFESHGKVIRRVRKVAEELDR------ 75
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
++AI D GP+IR G L+ + L KG I LTT + G+ D I V+YK +
Sbjct: 76 TVAILADLPGPKIRVGKLK---KEPLMLHKGNRITLTTD---ETSGSEDRIPVNYKQLPE 129
Query: 530 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 709
V PG+ I++ DG I ++C +S + C + GG L S KG+NLPG + L +V+E D
Sbjct: 130 SVSPGSLIYLSDGFIQLLCLEISGKDVVCEVMVGGQLYSHKGLNLPGAKIYLDSVTEHDF 189
Query: 710 SDLLFGVEQGVDMIFASFI 766
L F + + VD + SF+
Sbjct: 190 KILEFALNEEVDAVSISFV 208
>UniRef50_A7CUA8 Cluster: Pyruvate kinase; n=1; Opitutaceae
bacterium TAV2|Rep: Pyruvate kinase - Opitutaceae
bacterium TAV2
Length = 480
Score = 142 bits (343), Expect = 1e-32
Identities = 76/210 (36%), Positives = 126/210 (60%), Gaps = 2/210 (0%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
IR + I+ T+GPA+ + +LEK++ G +VAR+N +H +HE+ IR RE K +
Sbjct: 10 IRRTKIVFTLGPATESEEMLEKLIRAGADVARLNMAHANHEWTRMIIRRIREVSK----R 65
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNAD--TIYV 508
+G +AI +D KGPEIRTG + S+ +ELK GE T + + + ++ V
Sbjct: 66 VGR--EIAIMMDIKGPEIRTGDV----SSPIELKAGEIFDFTIRPGAAQDSSEEVRSVDV 119
Query: 509 DYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLP 688
+YK++ N ++ G+ + +D+GLI + + C + G L SR+ +NLPG+ V+LP
Sbjct: 120 NYKDLVNDIRVGDTVLVDNGLIRLEVLEKQNTRIRCRVLIPGELKSRRHINLPGVKVNLP 179
Query: 689 AVSEKDKSDLLFGVEQGVDMIFASFIRNGA 778
+++EKDK+DL G+ +G+D + SF+R A
Sbjct: 180 SLTEKDKTDLAVGLIEGIDFVALSFVREAA 209
>UniRef50_Q1IHI1 Cluster: Pyruvate kinase; n=2; Bacteria|Rep:
Pyruvate kinase - Acidobacteria bacterium (strain
Ellin345)
Length = 509
Score = 141 bits (342), Expect = 2e-32
Identities = 74/204 (36%), Positives = 115/204 (56%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
R + I+CTIGPA A ++++M GM+VAR+NFSHG+H+ H I+ R+
Sbjct: 20 RRAKIVCTIGPACNTEAAMQELMRAGMDVARLNFSHGTHDEHLVVIQRLRKVAAEEQR-- 77
Query: 338 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 517
S+ I D +GP+IRTGLL+ V L+ G T+ +T G+A + ++
Sbjct: 78 ----SICILQDLQGPKIRTGLLKD--HKPVMLETGNTVTITPRDIV---GDASLLATTFQ 128
Query: 518 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 697
+ V+PG+RI + DG I + + + C I NGG L +G+N+PG + +PA++
Sbjct: 129 TLALDVQPGSRILLSDGKIELSVSRIEGADVECHIVNGGELKEHQGINIPGAILSIPALT 188
Query: 698 EKDKSDLLFGVEQGVDMIFASFIR 769
KD DL FG++ GVD + SF+R
Sbjct: 189 NKDLEDLAFGLKNGVDAVAISFVR 212
>UniRef50_Q1Q4I4 Cluster: Strongly similar to pyruvate kinase; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Strongly
similar to pyruvate kinase - Candidatus Kuenenia
stuttgartiensis
Length = 472
Score = 141 bits (341), Expect = 2e-32
Identities = 80/204 (39%), Positives = 119/204 (58%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
R + I+CTIGPAS + A++E+++ GMNVAR+NFSHG H E I + R + S KL
Sbjct: 5 RKTKIVCTIGPASNSPAMIEQLICAGMNVARLNFSHGELSQHKECISHIR----AISEKL 60
Query: 338 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 517
P +A+ D GP+IR G+L G V LK +T LTT + GN I ++Y
Sbjct: 61 MQP--VAVLQDLSGPKIRIGMLSGDA---VTLKTNDTFTLTTRNIV---GNERVISINYS 112
Query: 518 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 697
++ V G+ + + DG I + + C + GG+L SRKG+N+P + + +++
Sbjct: 113 DLPMNVSIGDTLLLSDGEIEVEVIQKDDRNIHCKVIVGGVLTSRKGINIPARSLPVSSLT 172
Query: 698 EKDKSDLLFGVEQGVDMIFASFIR 769
EKDK DL FG+EQGVD + SF++
Sbjct: 173 EKDKKDLEFGIEQGVDYVAMSFVK 196
>UniRef50_A5C814 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Rep:
Pyruvate kinase - Vitis vinifera (Grape)
Length = 621
Score = 141 bits (341), Expect = 2e-32
Identities = 74/210 (35%), Positives = 123/210 (58%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
R + I+CTIGP++ + ++ K+ ETGMNVAR+N SHG H H +TI +E + K+
Sbjct: 166 RKTKIVCTIGPSTSSREMIWKLAETGMNVARLNMSHGDHASHKKTIDLVKEYNAQFEDKV 225
Query: 338 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 517
+AI LDTKGPE+R+G + + LK+G+ T + +T+ V+Y
Sbjct: 226 -----IAIMLDTKGPEVRSGDVP----KPIMLKEGQEFNFTIKRGVSSE---NTVSVNYD 273
Query: 518 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 697
+ N V+ G+ + +D G++S+ +S S D + C + +GG L SR+ +N+ G LP+++
Sbjct: 274 DFVNDVEVGDILLVDGGMMSLAVKSKSKDLVKCQVIDGGELKSRRHLNVRGKSATLPSIT 333
Query: 698 EKDKSDLLFGVEQGVDMIFASFIRNGAALH 787
+KD D+ FGV+ VD SF+++ +H
Sbjct: 334 DKDWEDIKFGVDNQVDFYAVSFVKDAEVVH 363
>UniRef50_Q2S3S2 Cluster: Pyruvate kinase; n=1; Salinibacter ruber
DSM 13855|Rep: Pyruvate kinase - Salinibacter ruber
(strain DSM 13855)
Length = 476
Score = 140 bits (340), Expect = 3e-32
Identities = 72/204 (35%), Positives = 116/204 (56%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
R + I+CT+GPA+ + L +++ GM+VARMNFSHG+HE H E + RE ++
Sbjct: 3 RRTKIVCTLGPATTDPETLRRLVAAGMDVARMNFSHGTHEEHRERVETVREVAEAEGK-- 60
Query: 338 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 517
+ + D +GP+IR G ++ V L +G+ ++++T D + + I++DY+
Sbjct: 61 ----GITVLQDLQGPKIRVGAVQNDS---VMLAEGDEVRVST--DTPRESTNEHIFIDYE 111
Query: 518 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 697
+ + G RI IDDGL+ + + L T+ GG L SRKGVNLP + P ++
Sbjct: 112 ALARDAREGERILIDDGLLELRVIETNGSQLRATVVEGGPLRSRKGVNLPDLQASTPPMT 171
Query: 698 EKDKSDLLFGVEQGVDMIFASFIR 769
EKD DL G+E VD++ SF++
Sbjct: 172 EKDLKDLELGLELEVDVVALSFVQ 195
>UniRef50_Q2I6K6 Cluster: Pyruvate kinase; n=1; uncultured delta
proteobacterium DeepAnt-32C6|Rep: Pyruvate kinase -
uncultured delta proteobacterium DeepAnt-32C6
Length = 466
Score = 139 bits (337), Expect = 6e-32
Identities = 80/209 (38%), Positives = 115/209 (55%), Gaps = 1/209 (0%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
+R + I+CTIGPA+ + +++ GM+ AR+NFSHG+ + HA RE + +
Sbjct: 1 MRRAKIVCTIGPATHTREGIRALIDAGMDCARLNFSHGTQQGHARVAALVREL----ATE 56
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
G P +A+ D GP+IR G G VEL +G LTT G ++Y
Sbjct: 57 AGRP--IALLADLCGPKIRVGRFPEGA---VELVEGTAFTLTTRD---VAGTDKQASINY 108
Query: 515 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 694
+ V PG+ I IDDGLI ++ + V + C +E GGML RKG+N+PG + PA+
Sbjct: 109 AALPQDVDPGDAIMIDDGLIRLVVREVEGPDIHCIVEVGGMLSERKGINVPGSALSTPAL 168
Query: 695 SEKDKSDLLFGVEQ-GVDMIFASFIRNGA 778
++KDK DL F V+ GVD I SF+R A
Sbjct: 169 TDKDKRDLAFAVDTIGVDWIALSFVRTAA 197
>UniRef50_Q1NTW3 Cluster: Pyruvate kinase; n=1; delta
proteobacterium MLMS-1|Rep: Pyruvate kinase - delta
proteobacterium MLMS-1
Length = 493
Score = 139 bits (336), Expect = 8e-32
Identities = 78/204 (38%), Positives = 119/204 (58%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
R + I+CTIGPA+ + + ++ E GMNVAR+N SHGS E+H I N + K Y+
Sbjct: 16 RRTKIVCTIGPATASFEAICRLAEQGMNVARLNMSHGSREWHRGVIGNIKRYNKKYAG-- 73
Query: 338 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 517
SLA+ LDT+G EIR+G L+ ++EL+ G+ + LTT Q + + V +
Sbjct: 74 ----SLAVLLDTRGAEIRSGDLK----QDLELRVGDGLTLTTRR--QAELEPGCVEVSHD 123
Query: 518 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 697
V PG+ I +D G++ + V + C + G+LGSR+ +N+ G DLPA++
Sbjct: 124 GFVAEVTPGDIILVDGGMLRLKVVEVGRTDVRCQSLDEGVLGSRRHLNIRGKSADLPAIT 183
Query: 698 EKDKSDLLFGVEQGVDMIFASFIR 769
E+D +D+ FG+EQ VD I SF+R
Sbjct: 184 EQDWADIEFGMEQRVDFIALSFVR 207
>UniRef50_Q8SQP0 Cluster: Pyruvate kinase; n=1; Encephalitozoon
cuniculi|Rep: Pyruvate kinase - Encephalitozoon cuniculi
Length = 519
Score = 139 bits (336), Expect = 8e-32
Identities = 74/202 (36%), Positives = 122/202 (60%)
Frame = +2
Query: 161 LSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLG 340
L+ I+CTIGP + + ++++++ GM++AR+NFSHGS E H E IRN R++ G
Sbjct: 96 LTKIVCTIGPRTSSREKIKELIDAGMSIARLNFSHGSREAHLEVIRNIRDSRS------G 149
Query: 341 SPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKN 520
+ ++IALDT+GPE+R E +++++ GE ++ + S ++ VD K+
Sbjct: 150 AGRHVSIALDTRGPEVRLRTPE---MKDIKVEGGEVLRFSLLSSEKDIWIPG---VDLKS 203
Query: 521 ITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 700
+ NR+FIDDG I + +V D C + N GM+ S K +N PG + A+ +
Sbjct: 204 LG----VDNRVFIDDGAIELRVVNVEEDGFECEVLNSGMIKSNKSMNFPGTDIGDRALGD 259
Query: 701 KDKSDLLFGVEQGVDMIFASFI 766
+DK+D+ FG+E G+DM+FASF+
Sbjct: 260 EDKNDIAFGLENGIDMVFASFV 281
>UniRef50_Q1IJ65 Cluster: Pyruvate kinase; n=6; Bacteria|Rep:
Pyruvate kinase - Acidobacteria bacterium (strain
Ellin345)
Length = 485
Score = 138 bits (335), Expect = 1e-31
Identities = 74/201 (36%), Positives = 120/201 (59%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
I+ TIGPAS + +LE+++ TG++VAR+NFSHG H E I N R A S + G
Sbjct: 10 IVGTIGPASESPEMLERLIRTGLDVARLNFSHGDFSGHRERIANLRAA----SDRAGR-- 63
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
++A+ D GP++R G ++ + + L+ G+ LTT S G+ + + +
Sbjct: 64 AVAVLADLPGPKMRLGTIQ---NEPIHLRAGDPFTLTTDSIV---GDNRRCSMSFAALPQ 117
Query: 530 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 709
VVKPG+R++++DGL+ ++ + + + C + GG L SRKG+NLPGI + + A +E D+
Sbjct: 118 VVKPGDRLYLNDGLVHLLVERIEGTDVHCVVAVGGELRSRKGLNLPGINLGISAFTEHDR 177
Query: 710 SDLLFGVEQGVDMIFASFIRN 772
L F +E GVD + SF++N
Sbjct: 178 DCLKFALENGVDAVSQSFVQN 198
>UniRef50_Q8F253 Cluster: Pyruvate kinase; n=4; Leptospira|Rep:
Pyruvate kinase - Leptospira interrogans
Length = 478
Score = 138 bits (334), Expect = 1e-31
Identities = 77/205 (37%), Positives = 115/205 (56%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
I+CTIGPAS + + +++ GM++ARMNFSHG+H+ H R+ E+ + F
Sbjct: 14 IVCTIGPASSSEETILSILKAGMDIARMNFSHGTHDSHKRVYDTLRKCEQIFG------F 67
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
L I D +GP+IRTG L+ + L K + I++ SD G+ I Y N+
Sbjct: 68 PLGIMADLQGPKIRTGKLKLNS---ILLHKNQEIEIVPDSDIL--GDEHKIGCTYPNLIR 122
Query: 530 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 709
++ ++I IDDG + + S +++ + GG+L S KG+NLPG P+ PA+SEKD
Sbjct: 123 DIQEEDKILIDDGKLILKVISKKSNSAILKVIVGGILWSNKGINLPGTPISAPALSEKDI 182
Query: 710 SDLLFGVEQGVDMIFASFIRNGAAL 784
DL F + GVD SF+R GA L
Sbjct: 183 EDLKFALSLGVDYAALSFVRTGADL 207
>UniRef50_Q6MAN9 Cluster: Pyruvate kinase; n=1; Candidatus
Protochlamydia amoebophila UWE25|Rep: Pyruvate kinase -
Protochlamydia amoebophila (strain UWE25)
Length = 598
Score = 138 bits (333), Expect = 2e-31
Identities = 80/201 (39%), Positives = 116/201 (57%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
I+CTIGPA ++ + +++ GMNVAR+NFSHG+ E H TI +EA +L P
Sbjct: 8 IVCTIGPACNSLEKIIELINVGMNVARLNFSHGTQEEHLRTINLLKEAR----CQLNLP- 62
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
LAI LDTKGPEIR G + G ++ L G+ +L + G+ + + NI +
Sbjct: 63 -LAIMLDTKGPEIRLGKIRDG---QIFLTVGQKWRLVKK---EVLGDESQVSIFPLNILD 115
Query: 530 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 709
+ G I DDG I+ S++ + I N GM+ S KGVN+P ++LPAV+EKD
Sbjct: 116 QLPVGTTILFDDGYIASRVIENSSEGVLVEINNSGMIRSSKGVNIPNTSLNLPAVTEKDI 175
Query: 710 SDLLFGVEQGVDMIFASFIRN 772
D+ FG Q +D+I ASF+R+
Sbjct: 176 DDIRFGCSQDIDLIAASFVRS 196
>UniRef50_Q5V4I8 Cluster: Pyruvate kinase; n=4;
Halobacteriaceae|Rep: Pyruvate kinase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 610
Score = 137 bits (332), Expect = 3e-31
Identities = 74/211 (35%), Positives = 119/211 (56%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
+R + I+CT+GPAS +V + + + GM+VAR+N SHGS E+ E I R+ +++
Sbjct: 15 MRSAKIVCTLGPASDSVDDIASLAKAGMSVARLNASHGSPEHRREMIDRIRQVDEAVEEP 74
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
+ A LD GPE+RT ++ ++L +G TI+ D A V
Sbjct: 75 V------AAMLDMPGPEVRTAEID----EPIQLTEGSTIRYVVGDD------ATPEEVGL 118
Query: 515 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 694
V+PG+R+ +DDG I + V +T+ T+ENGG L +RKGVN+PG+ +DLP +
Sbjct: 119 SQSITAVEPGDRVLLDDGRIETTVERVEDETVFATVENGGELAARKGVNVPGVELDLPTI 178
Query: 695 SEKDKSDLLFGVEQGVDMIFASFIRNGAALH 787
+E D+ +L E+ D + ASF+R+G ++
Sbjct: 179 TENDEQELDVAAEKEPDFVAASFVRDGEDIY 209
>UniRef50_P73534 Cluster: Pyruvate kinase 2; n=37; Bacteria|Rep:
Pyruvate kinase 2 - Synechocystis sp. (strain PCC 6803)
Length = 591
Score = 137 bits (332), Expect = 3e-31
Identities = 80/209 (38%), Positives = 124/209 (59%), Gaps = 4/209 (1%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
R + I+ TIGPA+++ VL ++++ G R+NFSHG H YH ++IR R+ + +L
Sbjct: 8 RRTKIVATIGPATQSKEVLRQLIQAGATTFRLNFSHGDHAYHQQSIRLIRQI----AFEL 63
Query: 338 GSPFSLAIALDTKGPEIRTG-LLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIY-VD 511
P + I D +GP+IR G L GS V+LK G+ LT+ + +TI +
Sbjct: 64 NQP--VGILQDLQGPKIRVGKFLNDAGS--VQLKNGDPYTLTS----RPVECTETISSIS 115
Query: 512 YKNITNVVKPGNRIFIDDGLISIICQSVS--ADTLTCTIENGGMLGSRKGVNLPGIPVDL 685
Y+ + + V G RI +DDG + ++ + V A L C + GG L S KGVN PG+ + +
Sbjct: 116 YEYLADEVPSGARILLDDGKLEMLVEEVDTVARDLHCRVIVGGTLSSNKGVNFPGVCLSV 175
Query: 686 PAVSEKDKSDLLFGVEQGVDMIFASFIRN 772
A+++KDK DL+FG++QGVD + SF+RN
Sbjct: 176 KAMTDKDKEDLMFGLDQGVDWVALSFVRN 204
>UniRef50_Q40546 Cluster: Pyruvate kinase isozyme G, chloroplast
precursor; n=58; Viridiplantae|Rep: Pyruvate kinase
isozyme G, chloroplast precursor - Nicotiana tabacum
(Common tobacco)
Length = 562
Score = 137 bits (332), Expect = 3e-31
Identities = 75/224 (33%), Positives = 125/224 (55%), Gaps = 3/224 (1%)
Frame = +2
Query: 125 GLDIDSKSSYI---RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETI 295
G + +S Y+ R + I+CTIGP++ + ++ K+ E GMNVAR+N SHG H H TI
Sbjct: 77 GYSLGQESVYLNSPRKTKIVCTIGPSTSSREMIWKLAEAGMNVARLNMSHGDHASHQRTI 136
Query: 296 RNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDY 475
+E + K+ +AI LDTKGPE+ + G + LK+G+ +
Sbjct: 137 DLVKEYNAQFEDKV-----IAIMLDTKGPEV----ISGDVPKPILLKEGQEFNFSIKRGV 187
Query: 476 QEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKG 655
+ DT+ V+Y + N V+ G+ + +D G++S+ +S ++D + C + +GG L SR+
Sbjct: 188 STE---DTVSVNYDDFINDVEAGDILLVDGGMMSLAVKSKTSDIVKCEVIDGGELKSRRH 244
Query: 656 VNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALH 787
+N+ G LP+++EKD D+ FGV VD SF+++ +H
Sbjct: 245 LNVRGKSATLPSITEKDWDDIKFGVNNQVDFYAVSFVKDAKVVH 288
>UniRef50_Q56XD5 Cluster: Pyruvate kinase; n=14; Magnoliophyta|Rep:
Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress)
Length = 579
Score = 137 bits (331), Expect = 3e-31
Identities = 75/216 (34%), Positives = 121/216 (56%)
Frame = +2
Query: 140 SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEK 319
SK + R + I+CT+GP++ ++ K+ E GMNVARMN SHG H H + I + K
Sbjct: 104 SKPTVRRKTKIVCTVGPSTNTREMIWKLAEAGMNVARMNMSHGDHASHKKVI----DLVK 159
Query: 320 SYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADT 499
Y+A+ ++AI LDTKGPE+R+G L + L G+ T
Sbjct: 160 EYNAQTKDN-TIAIMLDTKGPEVRSGDLP----QPIMLDPGQEFTFTIERGVS---TPSC 211
Query: 500 IYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPV 679
+ V+Y + N V+ G+ + +D G++S + +S + D++ C + +GG L SR+ +N+ G
Sbjct: 212 VSVNYDDFVNDVEAGDMLLVDGGMMSFMVKSKTKDSVKCEVVDGGELKSRRHLNVRGKSA 271
Query: 680 DLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALH 787
LP+++EKD D+ FGVE VD SF+++ +H
Sbjct: 272 TLPSITEKDWEDIKFGVENKVDFYAVSFVKDAQVVH 307
>UniRef50_P94685 Cluster: Pyruvate kinase; n=8; Chlamydiaceae|Rep:
Pyruvate kinase - Chlamydia trachomatis
Length = 485
Score = 136 bits (329), Expect = 6e-31
Identities = 77/200 (38%), Positives = 114/200 (57%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
IICTIGPA+ +LEK+++ GMNVAR+NFSHG+HE H TI +E +
Sbjct: 7 IICTIGPATNTPEMLEKLLDAGMNVARLNFSHGTHESHGRTIAILKELREKRQV------ 60
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
LAI LDTKGPEIR G +E + ++++ G+ + L + K + T+Y +
Sbjct: 61 PLAIMLDTKGPEIRLGQVE----SPIKVQPGDRLTLVSKEILGSKESGVTLYPSC--VFP 114
Query: 530 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 709
V+ + IDDG I + + + +N G + S K +++ I V LP ++EKD
Sbjct: 115 YVRERAPVLIDDGYIQAVVVNAQEHMVEIEFQNSGEIKSNKSLSIKDIDVALPFMTEKDI 174
Query: 710 SDLLFGVEQGVDMIFASFIR 769
+DL FGVEQ +D+I ASF+R
Sbjct: 175 ADLKFGVEQELDLIAASFVR 194
>UniRef50_Q44473 Cluster: Pyruvate kinase; n=4; Proteobacteria|Rep:
Pyruvate kinase - Agrobacterium vitis (Rhizobium vitis)
Length = 482
Score = 136 bits (328), Expect = 8e-31
Identities = 76/204 (37%), Positives = 114/204 (55%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
R S I+ T+GPAS + +L + G++ R+NFSHG+ HAE RN R E+ + A
Sbjct: 7 RRSKIVATVGPASSSPDMLRSLFLAGVDTFRLNFSHGARADHAEVYRNIRALEQEHDA-- 64
Query: 338 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 517
++A+ D +GP+IR G+L G ++L +G TI + E N I + ++
Sbjct: 65 ----AIAVLQDLQGPKIRIGVLAHG---RLDLARGSTIGFILGREGGEGMN--DIPLPHR 115
Query: 518 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 697
I V PG + IDDG I + V L C + NGG L +RKGVN+PG +D+ ++
Sbjct: 116 EIFEVAVPGMDLLIDDGRIKVRIMEVMDGRLVCEVLNGGALSNRKGVNVPGAVLDISPLT 175
Query: 698 EKDKSDLLFGVEQGVDMIFASFIR 769
KD+ DL FG+E GVD + SF++
Sbjct: 176 AKDREDLEFGLELGVDWVALSFVQ 199
>UniRef50_Q9RR62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep:
Pyruvate kinase - Deinococcus radiodurans
Length = 482
Score = 135 bits (327), Expect = 1e-30
Identities = 74/205 (36%), Positives = 114/205 (55%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
R + I+ T+GPASR+ VL +M++ G+NV R+NFSHG E H +T++ R+ S +
Sbjct: 6 RATKIVATVGPASRSTEVLGRMIDVGLNVVRLNFSHGDLEDHRQTVQMVRDLAVSKGVTI 65
Query: 338 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 517
G I D +GP+IR G G V L G+ +T + +GNA+ + YK
Sbjct: 66 G------ILQDLQGPKIRVGRFAEGS---VTLNPGQKFVITMD---EVEGNAERVGSTYK 113
Query: 518 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 697
+ V PG + +DDG +S+ V + + T+ GG L + KG+N+P + +PA+S
Sbjct: 114 GLAGDVTPGMTLLLDDGNMSLRVDHVRGNDIQTTVLIGGTLKNNKGINVPEADLTVPALS 173
Query: 698 EKDKSDLLFGVEQGVDMIFASFIRN 772
EKD D+ FG GVD + SF+R+
Sbjct: 174 EKDVQDMEFGASLGVDWVALSFVRS 198
>UniRef50_Q8YTZ8 Cluster: Pyruvate kinase; n=3; Nostocaceae|Rep:
Pyruvate kinase - Anabaena sp. (strain PCC 7120)
Length = 476
Score = 134 bits (324), Expect = 2e-30
Identities = 77/207 (37%), Positives = 122/207 (58%), Gaps = 1/207 (0%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
+R + IICT+GPA+ LE ++E GMNVAR+NFSHG++++HA+T + R+ SA
Sbjct: 1 MRRTKIICTVGPATSAPERLEALVEAGMNVARLNFSHGAYDFHAQTAQYLRQI----SAD 56
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNA-DTIYVD 511
P +AI D GP+IR G L G + ++ G+ + QEKG++ D + +
Sbjct: 57 RQKP--VAIMQDLCGPKIRLGTLPPEG---LMVEAGQEVTFVL----QEKGSSLDELPLP 107
Query: 512 YKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPA 691
+ +V+PG I I+DG + +I AD + + GG+L +RKGVNLP + + +
Sbjct: 108 LPTLFAMVRPGEPILINDGRVKLIVTDRDADRIRAIAKIGGLLSTRKGVNLPATRLPVSS 167
Query: 692 VSEKDKSDLLFGVEQGVDMIFASFIRN 772
++EKD DL FG++ VD + SF+R+
Sbjct: 168 ITEKDLQDLRFGIDLSVDWVAVSFVRS 194
>UniRef50_Q6AII5 Cluster: Pyruvate kinase; n=1; Desulfotalea
psychrophila|Rep: Pyruvate kinase - Desulfotalea
psychrophila
Length = 581
Score = 133 bits (321), Expect = 6e-30
Identities = 77/200 (38%), Positives = 114/200 (57%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
II T+GP S++V + +++ GMNVAR+N SHG E + I N +EA K
Sbjct: 6 IIATLGPQSQSVEEIYSLIQAGMNVARINLSHGDAESYKHLISNVKEARKLAEK------ 59
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
AI LD +GPEIR +E ++ L GE + +T + E + I +Y +
Sbjct: 60 DTAILLDNRGPEIRVSEME----EDIHLVDGEELVITNRA---ETVSPSRITTNYPQLAG 112
Query: 530 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 709
V+ G+RI +DDG +++ ++ + + + GG+L SRK V LP V+LP++SEKDK
Sbjct: 113 DVQVGSRILLDDGKLALEVLAIEDEEVITKVIAGGILSSRKRVALPDNEVNLPSLSEKDK 172
Query: 710 SDLLFGVEQGVDMIFASFIR 769
D+ FGVEQ VD I ASF+R
Sbjct: 173 EDIAFGVEQDVDFIAASFVR 192
>UniRef50_Q2JLA2 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep:
Pyruvate kinase - Synechococcus sp. (strain
JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone
B-Prime)
Length = 619
Score = 132 bits (320), Expect = 7e-30
Identities = 80/207 (38%), Positives = 112/207 (54%), Gaps = 2/207 (0%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
R + I+ TIGPAS N A+L +M+ G R+NFSHG HE H +IR R+ + L
Sbjct: 8 RRTKIVATIGPASSNPAILREMILQGATTLRLNFSHGDHELHRRSIRLIRQT----AMDL 63
Query: 338 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 517
G +AI D +GP+IR G G + LK G+ LT+ G+ + +V Y
Sbjct: 64 G--IQVAILQDLQGPKIRLGKFAEGS---ITLKAGDPFVLTSKPVL---GSQERSWVTYD 115
Query: 518 NITNVVKPGNRIFIDDGLISIICQSVS--ADTLTCTIENGGMLGSRKGVNLPGIPVDLPA 691
+ V G I IDDG + + ++V A L C GG L + KGVN PG+ + + A
Sbjct: 116 KLAQEVPEGATILIDDGRVEMRVEAVDPEAGELFCRTIVGGTLSNNKGVNFPGVRLSIRA 175
Query: 692 VSEKDKSDLLFGVEQGVDMIFASFIRN 772
V+ KDK DL FG+ QGVD + SF+R+
Sbjct: 176 VTPKDKEDLYFGLNQGVDWVALSFVRD 202
>UniRef50_A0QNT2 Cluster: Pyruvate kinase; n=1; Mycobacterium
smegmatis str. MC2 155|Rep: Pyruvate kinase -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 477
Score = 132 bits (319), Expect = 1e-29
Identities = 70/204 (34%), Positives = 111/204 (54%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
R + I+CT+GPA+ +VL ++++ GM+VAR+NFSH +H H+ RE +
Sbjct: 4 RRAKIVCTLGPATATSSVLTELVDAGMDVARLNFSHSTHAEHSALYGMVREIAAQRGRVV 63
Query: 338 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 517
G + D +GP+IR G G V GE + +TT G+ D + Y
Sbjct: 64 G------VLADLQGPKIRLGCFADG---PVVWATGEHVTITTEDC---PGDHDRVSTTYA 111
Query: 518 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 697
++ V+ G+R+ +DDG + + +V + C + +GG + KG++LP IPV +P +S
Sbjct: 112 GLSQDVRAGDRLLVDDGRVDLRVVAVDGPDIRCEVVDGGPVSDHKGISLPNIPVSVPPLS 171
Query: 698 EKDKSDLLFGVEQGVDMIFASFIR 769
+KD DL F +E G DMI SF+R
Sbjct: 172 DKDIEDLKFALELGADMIAMSFVR 195
>UniRef50_Q56301 Cluster: Pyruvate kinase; n=5; Thermococcaceae|Rep:
Pyruvate kinase - Thermococcus litoralis
Length = 220
Score = 132 bits (318), Expect = 1e-29
Identities = 72/199 (36%), Positives = 118/199 (59%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
II TIGPAS+ ++KM++ GM+VAR+NFSHG+ E HA+TI R+ + ++
Sbjct: 14 IIATIGPASKQKESIKKMIKAGMSVARINFSHGTLEEHAKTIETVRDVAEKLERRV---- 69
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
AI D G ++R G ++G V L+KG+ + LTT +G+ TI V++K++
Sbjct: 70 --AILGDLPGLKMRVGKIKGDS---VTLRKGDKVVLTTRDI---EGDETTIPVEFKDLPK 121
Query: 530 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 709
+V G+ I++ DG I + + V + + C + NGG+L S KG+N+P + + A++ +D
Sbjct: 122 LVSKGDTIYLSDGYIMLRVEEVRENEVECVVVNGGILFSHKGINIPKANLPIEAITPRDF 181
Query: 710 SDLLFGVEQGVDMIFASFI 766
+ F +E GVD I SF+
Sbjct: 182 EIIEFAIEHGVDAIGLSFV 200
>UniRef50_Q1AXJ8 Cluster: Pyruvate kinase; n=1; Rubrobacter
xylanophilus DSM 9941|Rep: Pyruvate kinase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 477
Score = 131 bits (317), Expect = 2e-29
Identities = 74/209 (35%), Positives = 121/209 (57%), Gaps = 2/209 (0%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
+R + I+ T+GPA+ + + ++ G++V R+NFSHG+H+ H + R REA +A+
Sbjct: 3 VRRTKIVATLGPATSSEESIGALVRAGVDVMRLNFSHGTHDMHLDNARTVREA----AAE 58
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
G ++AI D +GP+IRTG +EGG EL +G + + D+ G+A + Y
Sbjct: 59 AGR--NVAIMQDLQGPKIRTGEVEGG----TELVEGSRV-VIAPGDF--VGDASRLSTSY 109
Query: 515 KNITNVVKPGNRIFIDDGLISIICQSVSAD-TLTCTIENGGMLGSRKGVNLPGIPVDLPA 691
+ VKPG+R+ IDDGLI + +S+ + + C + GG + S KG+N P + +
Sbjct: 110 DRLAQDVKPGHRLLIDDGLIGLRVESIKENGEIVCEVLEGGPVSSHKGLNFPDSSLSISG 169
Query: 692 VSEKDKSDLLFGVEQ-GVDMIFASFIRNG 775
++EKD DL FG+E+ D + SF+R G
Sbjct: 170 LTEKDLEDLRFGLEELRPDWVAISFVRTG 198
>UniRef50_A6Q7D7 Cluster: Pyruvate kinase; n=19; cellular
organisms|Rep: Pyruvate kinase - Sulfurovum sp. (strain
NBC37-1)
Length = 488
Score = 129 bits (312), Expect = 7e-29
Identities = 71/203 (34%), Positives = 116/203 (57%), Gaps = 2/203 (0%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
II TIGPA+ + ++ +M G+N+ R+NFSHG+HEYH+E + R+A + G
Sbjct: 7 IIATIGPATDSYEKIKALMCAGVNLFRLNFSHGTHEYHSEVLGRIRKAIEETGLITG--- 63
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS--DYQEKGNADTIYVDYKNI 523
I D GP+IR G+LE + LK G+ ++ Y+ K + ++ +I
Sbjct: 64 ---ILQDISGPKIRVGMLE----EDFILKSGDILEFVKEEIVGYKVKEGVYRLCINEPDI 116
Query: 524 TNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEK 703
+ ++ G I++ DG+I + + SAD + IEN GML SRKGVN P + + ++EK
Sbjct: 117 LDQLEVGESIYMYDGIIRAVVKEKSADMVKVEIENNGMLSSRKGVNFPNTHLGINVLTEK 176
Query: 704 DKSDLLFGVEQGVDMIFASFIRN 772
DK D+L+G++ VD + SF+++
Sbjct: 177 DKKDILWGIKHEVDFMAISFVQH 199
>UniRef50_Q7UF82 Cluster: Pyruvate kinase; n=1; Pirellula sp.|Rep:
Pyruvate kinase - Rhodopirellula baltica
Length = 476
Score = 128 bits (310), Expect = 1e-28
Identities = 72/208 (34%), Positives = 116/208 (55%), Gaps = 4/208 (1%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
R + II TIGPA+ + L ++E G++V R+N +HG+ E+ E + R+ K S +
Sbjct: 5 RHTKIIATIGPATESPEKLAALIEAGVDVMRLNMAHGTPEWVGEIVARIRKVSKDISRHV 64
Query: 338 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTS--SDYQ--EKGNADTIY 505
A+ +D KGPEIRTG +E +ELK G+ + L T +D E +
Sbjct: 65 ------AVMMDVKGPEIRTGAVEDA----IELKAGDELVLFTEDCADQSAVESDGTPRVS 114
Query: 506 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDL 685
V+Y + + + I +D GL+ A T+ C + G+L SR+ +NLPG+ V+L
Sbjct: 115 VNYLGLPGAIDLDSTILVDSGLLHWHVLKKDATTVRCRVITPGVLESRRHINLPGVQVNL 174
Query: 686 PAVSEKDKSDLLFGVEQGVDMIFASFIR 769
PA+++KD++DL GV+ G+D + SF+R
Sbjct: 175 PAITDKDRTDLAAGVKAGIDFVALSFVR 202
>UniRef50_A4MK73 Cluster: Pyruvate kinase; n=1; Petrotoga mobilis
SJ95|Rep: Pyruvate kinase - Petrotoga mobilis SJ95
Length = 478
Score = 128 bits (310), Expect = 1e-28
Identities = 72/200 (36%), Positives = 116/200 (58%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
I+CTIGPA+++ +++K++ GMNVAR+N SH + H + + ++ K L PF
Sbjct: 12 IVCTIGPATQDETMIKKLINAGMNVARLNTSHDTIADHEKRVNLIKKIRKD----LNIPF 67
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
AI LD +GP+IRTG E + +V L++G+ LT + GN + + ++Y+ +
Sbjct: 68 --AILLDLEGPKIRTGKFE---TDQVMLEEGQKFILTIE---EIVGNKERVSINYRELPK 119
Query: 530 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 709
VK G+ I +DDG I ++ S + + + GG + R+G+N+PGI + LP ++EKD
Sbjct: 120 EVKKGDFILLDDGKIRLVVVSSNEKEIVTKVVTGGSITHRRGINVPGIDISLPPLTEKDM 179
Query: 710 SDLLFGVEQGVDMIFASFIR 769
L VE VD I SF+R
Sbjct: 180 EYLNKAVEWNVDYIAQSFVR 199
>UniRef50_A0L7K0 Cluster: Pyruvate kinase; n=1; Magnetococcus sp.
MC-1|Rep: Pyruvate kinase - Magnetococcus sp. (strain
MC-1)
Length = 569
Score = 128 bits (310), Expect = 1e-28
Identities = 70/206 (33%), Positives = 109/206 (52%), Gaps = 1/206 (0%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
R + I+ T+GPA +V + +++E G++VAR+N SHG H+ H E I N REA + ++
Sbjct: 3 RRAKIVATLGPACSSVEQITRLIEAGLDVARLNMSHGDHKAHLELIHNVREASRIAKREV 62
Query: 338 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIY-VDY 514
A+ D +GP+IR G L+ + L+KG+ + + K D I Y
Sbjct: 63 ------ALLCDLQGPKIRVGHLD----EPLRLEKGQQWAIIPEGSHPPKLKCDGIIPCTY 112
Query: 515 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 694
+ PG RI DDG + L IE+GG+L S KG+N+P + P++
Sbjct: 113 AGLAKDAVPGCRILFDDGYLQARAIGTEEGALLVNIEHGGLLKSHKGINMPDASISAPSL 172
Query: 695 SEKDKSDLLFGVEQGVDMIFASFIRN 772
+ KD+ DL FGV+ VD + SF+R+
Sbjct: 173 TTKDQQDLFFGVKHDVDYVALSFVRS 198
>UniRef50_A7D456 Cluster: Pyruvate kinase; n=2;
Halobacteriaceae|Rep: Pyruvate kinase - Halorubrum
lacusprofundi ATCC 49239
Length = 613
Score = 128 bits (308), Expect = 2e-28
Identities = 77/232 (33%), Positives = 122/232 (52%), Gaps = 3/232 (1%)
Frame = +2
Query: 86 TVANVGSQLQHMCGLDID-SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFS 262
TV NV S CG + +KS +R + I+CTIGPAS + + + + GM+V R+N S
Sbjct: 5 TVTNVHSVATQPCGFFLSCAKSGDMRNAKIVCTIGPASDSRDAIRDLADAGMSVVRLNAS 64
Query: 263 HGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKG 442
HG+ + E I R + ++ P LA+ +D KGPE+RT L+
Sbjct: 65 HGTTAHREEVIERARAVDN----EIDDP--LAVMVDLKGPEVRTAELD------------ 106
Query: 443 ETIKLTTSSD--YQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTC 616
E+I L T S+ + E +A V + PG+ + +DDG I + V +++
Sbjct: 107 ESISLATGSEVTFVEGDDATPERVGLTHSIAAAGPGDTVLLDDGRIECRVERVDGESVVA 166
Query: 617 TIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRN 772
T+ +GG L SRKGVNLPG+ +D+ ++ +D+++L D + ASF+RN
Sbjct: 167 TVVSGGKLSSRKGVNLPGVAIDVDLITAEDEAELDLAARTNADFVAASFVRN 218
>UniRef50_A6LH43 Cluster: Pyruvate kinase; n=2; Parabacteroides|Rep:
Pyruvate kinase - Parabacteroides distasonis (strain
ATCC 8503 / DSM 20701 / NCTC11152)
Length = 485
Score = 126 bits (305), Expect = 5e-28
Identities = 73/201 (36%), Positives = 113/201 (56%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
I+ T+ +VA +E + + GMNV R+N +H E + N R + S ++G
Sbjct: 7 IVATVSDQRCDVAFVEALYKAGMNVVRLNTAHMMEEGLTRVVNNVR----TVSDRIG--- 59
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
I +DTKGPE+RT + K GE +K+ + D QE + D I V YKN N
Sbjct: 60 ---ILMDTKGPEVRTTTTVN--KEPIPFKTGEIVKVIGNPD-QETSH-DCICVSYKNFVN 112
Query: 530 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 709
+ G+ I IDDG + + S D L C I+N LGSRK VN+PG+ ++LP+++EKD+
Sbjct: 113 DLAIGSDILIDDGDLEMKVTGKSGDCLLCEIQNDATLGSRKSVNVPGVRINLPSLTEKDR 172
Query: 710 SDLLFGVEQGVDMIFASFIRN 772
+++L+ ++ +D I SF+RN
Sbjct: 173 NNILWAIDHDLDFIAHSFVRN 193
>UniRef50_Q8G5M1 Cluster: Pyruvate kinase; n=23;
Actinobacteridae|Rep: Pyruvate kinase - Bifidobacterium
longum
Length = 509
Score = 126 bits (304), Expect = 6e-28
Identities = 69/212 (32%), Positives = 120/212 (56%), Gaps = 2/212 (0%)
Frame = +2
Query: 140 SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEK 319
++ +++R + I+ TIGP++ + L K++E GM+VAR+N SHG+ E H + N R+A +
Sbjct: 25 NRQAFMRKAKIVDTIGPSTEDYDNLLKLVEAGMDVARLNRSHGTPEDHLKVYNNVRKASE 84
Query: 320 SYSAKLGSPFSLAIALDTKGPEIRTGLLE--GGGSAEVELKKGETIKLTTSSDYQEKGNA 493
+ ++A +D +GP+IR G + G +V+L+ G+ +TT +G+
Sbjct: 85 ATGR------NVAALVDLQGPKIRCGWFKKNADGEDKVQLQLGQEFVITTDD---VEGDE 135
Query: 494 DTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGI 673
+K + PG+ I IDDG + + V + + + G + S KG+NLPG+
Sbjct: 136 HITSTTFKGLPGDCHPGDPILIDDGKVRLEVTKVEGNNVYTKVVVAGPVSSHKGINLPGV 195
Query: 674 PVDLPAVSEKDKSDLLFGVEQGVDMIFASFIR 769
V LPA++EKD++DL + + G D+I SF+R
Sbjct: 196 AVSLPALTEKDEADLRWAIRTGADIIAMSFVR 227
>UniRef50_A6FYT4 Cluster: Pyruvate kinase; n=1; Plesiocystis
pacifica SIR-1|Rep: Pyruvate kinase - Plesiocystis
pacifica SIR-1
Length = 485
Score = 126 bits (303), Expect = 8e-28
Identities = 71/205 (34%), Positives = 116/205 (56%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
+R + I+ T+GPAS + ++ +M+ G++ R+NFSHGSHE HA+ RE + S +
Sbjct: 6 LRRAKILGTLGPASNSDEMIGALMDAGLDAVRLNFSHGSHEDHAQVYGKVRE-QSSIRRR 64
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
+A+ D +GP+IR G + G + L+ GET+ T D + + + +DY
Sbjct: 65 -----PVAVLGDLQGPKIRVGKIPDPG---MTLETGETLVFLT--DPTAEISQGRVTIDY 114
Query: 515 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 694
+ K G R+ +DDG + ++A + + NGG+L +RKGVNLP + LP++
Sbjct: 115 PTLDEEAKVGERVLMDDGELEARITEINAGEVHAEMLNGGVLKARKGVNLPDSDLLLPSL 174
Query: 695 SEKDKSDLLFGVEQGVDMIFASFIR 769
++KD DL F +E GVD + SF+R
Sbjct: 175 TDKDAKDLRFALELGVDFVALSFVR 199
>UniRef50_UPI0000DB6F59 Cluster: PREDICTED: similar to Pyruvate
kinase CG7070-PB, isoform B; n=1; Apis mellifera|Rep:
PREDICTED: similar to Pyruvate kinase CG7070-PB, isoform
B - Apis mellifera
Length = 538
Score = 124 bits (299), Expect = 3e-27
Identities = 66/239 (27%), Positives = 123/239 (51%), Gaps = 2/239 (0%)
Frame = +2
Query: 77 EKPTVANVGSQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMN 256
E+ A ++L+H L+I+S RL+ I+ T+G + + + +M G N+ R+N
Sbjct: 12 EQIKAAYQNTRLEHNINLNINSSPKLARLTRIMVTLGRRNSHPEAVVSIMMAGANIVRLN 71
Query: 257 FSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSA--EVE 430
+H + ++H T+++ R+A + + L +A++ +GPEIR G G ++ +
Sbjct: 72 MAHETDKWHTATVQSVRKAGNTMYEFTSEIYPLGVAINLQGPEIRAGAFRGDKTSLGYAK 131
Query: 431 LKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTL 610
LK+G+ +KL T + G A+ +V Y N+ + + G+RI ID G + + + +
Sbjct: 132 LKEGKMVKLVTQDIAKRAGRANCFWVSYPNLPKICQVGDRILIDRGAVLLQVTCIHEQAI 191
Query: 611 TCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALH 787
TC I GG++ K + L V LP +SEKD + + + D + + +RN L+
Sbjct: 192 TCKIIKGGIVKDGKLIQLLDSLVPLPQISEKDIAHVKWASHLECDFLIMNHVRNEKVLY 250
>UniRef50_A4APL1 Cluster: Pyruvate kinase; n=15; Bacteroidetes|Rep:
Pyruvate kinase - Flavobacteriales bacterium HTCC2170
Length = 480
Score = 123 bits (297), Expect = 4e-27
Identities = 69/207 (33%), Positives = 114/207 (55%), Gaps = 1/207 (0%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
I+ + I+ T+GPA+ V+ M++ G++V R+NFSH +E ++ RE + +
Sbjct: 4 IKKTKIVATLGPATSKKEVIIDMIKAGVDVFRINFSHADYEDVTARVKMIREVNEEIDS- 62
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
++AI D +GP++R G++ G EV + G+ I T ++ GN++ +Y++Y
Sbjct: 63 -----NIAILGDLQGPKLRVGVMSG----EVVVTPGDEIDFVTGEPFE--GNSERVYMNY 111
Query: 515 KNITNVVKPGNRIFIDDG-LISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPA 691
V PG RI +DDG L+ + + D + + GG L S+KGVNLP + LPA
Sbjct: 112 AAFPKDVNPGERILLDDGKLMFEVVSTNKKDKVRAKVIQGGPLKSKKGVNLPNTNISLPA 171
Query: 692 VSEKDKSDLLFGVEQGVDMIFASFIRN 772
++EKD D F + VD I SF+R+
Sbjct: 172 LTEKDVKDAKFAISLDVDWIALSFVRH 198
>UniRef50_Q6YQT6 Cluster: Pyruvate kinase; n=6; Candidatus
Phytoplasma|Rep: Pyruvate kinase - Onion yellows
phytoplasma
Length = 446
Score = 123 bits (296), Expect = 6e-27
Identities = 72/202 (35%), Positives = 116/202 (57%), Gaps = 2/202 (0%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
IICT+GPAS + +L+ +++TG+NVAR NFSH +E ++ K+ S KL
Sbjct: 6 IICTLGPASYDKNILQALIQTGLNVARFNFSHAQYEQTKLLMKTI----KTISDKLDK-- 59
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
+ + LDTKGPEIRT +G V ++K +K++ + + GNA V Y N+ N
Sbjct: 60 NTGLMLDTKGPEIRTHEFDG----VVTIQKDSEVKISMT---EVLGNAKLFSVSYSNLYN 112
Query: 530 VVKPGNRIFIDDGLIS--IICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEK 703
+K G+ + IDDG +S ++ + + L +N + SR+GVN+P + +++ +S K
Sbjct: 113 ELKVGDMVNIDDGYLSLEVVGKDEAKQQLVTKAKNTHSIKSRRGVNVPKVNLEMDFISPK 172
Query: 704 DKSDLLFGVEQGVDMIFASFIR 769
D D++F +Q D I ASF+R
Sbjct: 173 DYQDIVFAAQQDFDYIAASFVR 194
>UniRef50_UPI00015BD1E0 Cluster: UPI00015BD1E0 related cluster; n=1;
unknown|Rep: UPI00015BD1E0 UniRef100 entry - unknown
Length = 477
Score = 122 bits (295), Expect = 8e-27
Identities = 68/201 (33%), Positives = 113/201 (56%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
I+CTIGPAS+ V L KM+E GMN+AR+NF+HGS E H + N R+A K
Sbjct: 11 IVCTIGPASQEVETLTKMIENGMNIARINFAHGSFEEHETVVENIRKASKIVGK------ 64
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
+ I D GP+IR G ++ +E+KKG+ + L+ EK I +++K+ +
Sbjct: 65 DVTIMGDLPGPKIRIGDIK-----PMEIKKGDILILS------EKPQEGVIPINFKDFSK 113
Query: 530 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 709
VK G+ I+++DG + ++ + V D + + G + S KGVNLP + + + A+ + +K
Sbjct: 114 YVKVGDSIYMNDGFVELMVEKVEDDKVYAVSLSAGKISSHKGVNLPNVDLPVRAIGDYEK 173
Query: 710 SDLLFGVEQGVDMIFASFIRN 772
+ F + +D I SF+++
Sbjct: 174 RCIDFAKKIDMDAISVSFVKD 194
>UniRef50_A1BQT0 Cluster: Pyruvate kinase; n=2; Eukaryota|Rep:
Pyruvate kinase - Monocercomonoides sp. PA203
Length = 516
Score = 122 bits (295), Expect = 8e-27
Identities = 71/210 (33%), Positives = 116/210 (55%), Gaps = 2/210 (0%)
Frame = +2
Query: 146 SSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSY 325
+S+ L+ I+ T+GPA+ + +++ G+NV RMNFSHG+HE+H + + R+ +
Sbjct: 32 ASFTPLTKIVATLGPATSTYETISQVVTAGVNVIRMNFSHGTHEFHEQLYKIVRKVAED- 90
Query: 326 SAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIY 505
LG +AI D +GP++RT GG ++ +K+G+ + + S + + G T +
Sbjct: 91 ---LGK--EVAIIADLQGPKVRTNTFPGG---KITIKRGDKVSIVGSPEPGKPGVITTKF 142
Query: 506 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPV-D 682
NV +P + IDDGLI +I Q + + L C +E GG + KG+NLP +
Sbjct: 143 TPMITHCNVGEP---VLIDDGLIRLIVQEKNPNELVCLVEQGGDVKDHKGINLPATDLGP 199
Query: 683 LPAVSEKDKSDLLFGVEQ-GVDMIFASFIR 769
LPA++EKD D F ++ VD SF+R
Sbjct: 200 LPALTEKDIEDAKFVLDTLEVDFFALSFVR 229
>UniRef50_A6Q5W9 Cluster: Pyruvate kinase; n=2;
Epsilonproteobacteria|Rep: Pyruvate kinase -
Nitratiruptor sp. (strain SB155-2)
Length = 458
Score = 122 bits (293), Expect = 1e-26
Identities = 73/204 (35%), Positives = 117/204 (57%)
Frame = +2
Query: 161 LSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLG 340
++ I+ TIGP+S + ++K++ G+NV R+NFSH H+ H +I+ RE K KLG
Sbjct: 1 MTKIVATIGPSS--IEKIDKLILAGVNVFRLNFSHADHKTHKASIKKIRETAK----KLG 54
Query: 341 SPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKN 520
+ AI D GP+IR G ++G +EL KG+ I+L + K D + + Y
Sbjct: 55 T--KTAILQDISGPKIRIGEVDG----ILELSKGDKIRLVKT---HPKSKYD-LTLSYPQ 104
Query: 521 ITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 700
I + ++ G +F DG I +D++T ++N G+L SRKGVN P + L A++
Sbjct: 105 IIDDLEVGEYVFFADGTIRTKVIEKDSDSVTLLVKNPGVLSSRKGVNFPHSNLRLSAITP 164
Query: 701 KDKSDLLFGVEQGVDMIFASFIRN 772
KD+ DL FG ++GVD++ SF+ +
Sbjct: 165 KDEKDLRFGAKEGVDIVAISFVNS 188
>UniRef50_A6C474 Cluster: Pyruvate kinase; n=1; Planctomyces maris
DSM 8797|Rep: Pyruvate kinase - Planctomyces maris DSM
8797
Length = 489
Score = 122 bits (293), Expect = 1e-26
Identities = 67/203 (33%), Positives = 118/203 (58%), Gaps = 2/203 (0%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
II T+GPAS + +L+K++ G+++ R+NF+HG HE+ +E ++N E SA++ P
Sbjct: 17 IIATVGPASDSREMLQKLIIAGVDLFRLNFAHGKHEWLSEIVKNIHEI----SAEMEKP- 71
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
+ I D GP+IR G+L G E+ ++ + D N + Y+++
Sbjct: 72 -IGILGDLSGPKIRLGVLPGD---EITCRQDMRFRFIQGLD---SDNPQELTCTYESLIG 124
Query: 530 VVKPGNRIFIDDGLISIICQSVSADT--LTCTIENGGMLGSRKGVNLPGIPVDLPAVSEK 703
++ G+ + + DG++++ SAD + C +E G++ S++GVNLPG+ + P ++EK
Sbjct: 125 DLRVGDPVLLADGMVAMRVVEKSADDEFVECVVEREGIIRSKQGVNLPGVQLSTPCLTEK 184
Query: 704 DKSDLLFGVEQGVDMIFASFIRN 772
D SDL + VE G+D I SF+R+
Sbjct: 185 DLSDLAWAVEHGLDYIGLSFVRS 207
>UniRef50_Q6KHW9 Cluster: Pyruvate kinase; n=3; Mycoplasma|Rep:
Pyruvate kinase - Mycoplasma mobile
Length = 483
Score = 121 bits (292), Expect = 2e-26
Identities = 76/203 (37%), Positives = 112/203 (55%)
Frame = +2
Query: 164 SGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGS 343
S +I TIGP+S+N +L++MM GM R NFSHG H AE + A K + +L
Sbjct: 17 SKMIATIGPSSQNKEILKQMMLKGMTTVRANFSHGDH---AEQLNKFVLA-KEVAKELNL 72
Query: 344 PFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNI 523
P SL LDTKGPEIR G ++ G S ++E+ K T+ LT Y+ T + +
Sbjct: 73 PMSLM--LDTKGPEIRVGKMKDG-SQKIEVGKIITV-LTDEVSYKTFEGIPTKFTVSHRM 128
Query: 524 TNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEK 703
VK G+ I DDG ++ I V + + N +L S K +N+PG + L +S+K
Sbjct: 129 DKDVKVGSYILFDDGKLTTIVTGVKSGIVEVKTINSHVLKSNKRINIPGAQLSLEFLSKK 188
Query: 704 DKSDLLFGVEQGVDMIFASFIRN 772
DK D++FG++ V+ I ASF+ +
Sbjct: 189 DKEDIIFGIKNDVNYIAASFVNS 211
>UniRef50_A6DH47 Cluster: Pyruvate kinase; n=1; Lentisphaera
araneosa HTCC2155|Rep: Pyruvate kinase - Lentisphaera
araneosa HTCC2155
Length = 485
Score = 121 bits (292), Expect = 2e-26
Identities = 71/207 (34%), Positives = 116/207 (56%), Gaps = 2/207 (0%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
I+ T+GP ++ L++++E G++V R+NFSHGSHE HAE I+ A +G
Sbjct: 9 IVSTLGPTTKGR--LKELIEEGVDVFRLNFSHGSHEEHAERIQEVISAATELKRTVG--- 63
Query: 350 SLAIALDTKGPEIRTG-LLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNIT 526
I D +GP+IR G ++EGG ++L+ G+ + +TT E T++ + +
Sbjct: 64 ---ILGDLQGPKIRCGKIIEGG----IQLEAGQELVITTDEILGEGSRISTVF---QALP 113
Query: 527 NVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKD 706
VK G+ I +DDGL+ + + + + + C + G L S KG+NLP + PA++EKD
Sbjct: 114 REVKVGDPILMDDGLLEAVVERIEGNEIFCKMLVAGKLTSNKGINLPETDIQSPALTEKD 173
Query: 707 KSDLLFGVE-QGVDMIFASFIRNGAAL 784
+ DL F +E +D + SF+R G L
Sbjct: 174 ERDLKFIIENDAIDFVALSFVRKGEDL 200
>UniRef50_A0L5K6 Cluster: Pyruvate kinase; n=5; Proteobacteria|Rep:
Pyruvate kinase - Magnetococcus sp. (strain MC-1)
Length = 483
Score = 118 bits (283), Expect = 2e-25
Identities = 67/205 (32%), Positives = 115/205 (56%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
IR + II T+GP + + ++ + TG++ R+NFSHGSHE H R E+ +
Sbjct: 4 IRRTKIIATLGPNASSRDFIKHLALTGVDTFRLNFSHGSHEDHRRRHGWIRSVEE----E 59
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
LG P L I +D +GP++R G E ++EVEL +G+ L + G+ + + + +
Sbjct: 60 LGRP--LGIMMDLQGPKLRIGTFE---NSEVELVRGQKFALYKE---ERTGDINGVTLPH 111
Query: 515 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 694
+ V++PG + ++DG I++ V + C + GG+L RKG+N+P + + A+
Sbjct: 112 NELFQVMRPGLELLLNDGRINLRVMEVEDFGVCCEVRVGGILSDRKGLNVPAAMLPVKAL 171
Query: 695 SEKDKSDLLFGVEQGVDMIFASFIR 769
++KD DL FG+E G+D SF++
Sbjct: 172 TDKDLEDLEFGLELGIDWCALSFVQ 196
>UniRef50_Q64MR8 Cluster: Pyruvate kinase; n=6; Bacteroides|Rep:
Pyruvate kinase - Bacteroides fragilis
Length = 485
Score = 117 bits (282), Expect = 3e-25
Identities = 65/206 (31%), Positives = 111/206 (53%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
++ + I+ +I +V ++++ + GMNV RMN +H S E I N R
Sbjct: 3 LKQTKIVASISDRRCDVDFIKELFDAGMNVVRMNTAHASREGFEALIANVRAVSNR---- 58
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
+AI +DTKGPE+RT + + + GE +K+ D + + I V Y
Sbjct: 59 ------IAILMDTKGPEVRTT----ANADPILYQIGEKVKIVGDPDRET--TRECIAVSY 106
Query: 515 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 694
N + + G I IDDG + + + + L C ++N LGSRK VN+PG+ ++LP++
Sbjct: 107 PNFVHDLNVGGTILIDDGDLELRVIDKTTEYLLCEVQNEATLGSRKSVNVPGVRINLPSL 166
Query: 695 SEKDKSDLLFGVEQGVDMIFASFIRN 772
+EKD++++L+ +E+ +D I SF+RN
Sbjct: 167 TEKDRNNILYAIEKDIDFIAHSFVRN 192
>UniRef50_Q82XE9 Cluster: Pyruvate kinase family; n=130;
Proteobacteria|Rep: Pyruvate kinase family -
Nitrosomonas europaea
Length = 496
Score = 117 bits (281), Expect = 4e-25
Identities = 66/207 (31%), Positives = 108/207 (52%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
+R + I+ T+GPAS N VL +M+E G++V R+NFSHG+ + H ++ R +S
Sbjct: 2 MRRTKIVATLGPASSNAEVLGRMLEAGVDVIRINFSHGTKDEHIASVELVRSLARSLGRT 61
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
+G + D +GP+IR G E G ++ LK G+ L + GN + + +DY
Sbjct: 62 VG------VLADLQGPKIRIGKFEQG---KIRLKTGDEFILDAEC---QLGNQERVGLDY 109
Query: 515 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 694
+ + N V+ G + +DDG I + V + C + GG+L + KG+N G + PA+
Sbjct: 110 RELPNDVEAGATLLLDDGRIVLTVAKVRESEIFCEVLQGGILSNNKGINRKGGGLSAPAL 169
Query: 695 SEKDKSDLLFGVEQGVDMIFASFIRNG 775
+ KD D+ D + SF R+G
Sbjct: 170 TAKDLLDIKTSAVIRADYLAVSFPRSG 196
>UniRef50_A7CAK5 Cluster: Pyruvate kinase; n=3; Ralstonia
pickettii|Rep: Pyruvate kinase - Ralstonia pickettii 12D
Length = 507
Score = 117 bits (281), Expect = 4e-25
Identities = 67/211 (31%), Positives = 107/211 (50%)
Frame = +2
Query: 137 DSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAE 316
++K R + I+ T+GPAS + + + + G +V R+NFSHGSHE H + R E
Sbjct: 13 NTKMRRFRNTKILATLGPASSDKDTIRALFDAGADVFRLNFSHGSHEDHRKRYDTVRAVE 72
Query: 317 KSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNAD 496
A+ G P + I D +GP++R G G V LK G+ L G+
Sbjct: 73 ----AETGRP--IGILADMQGPKLRIGTFADG---RVVLKNGDRFVLDRDPT---PGDVT 120
Query: 497 TIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIP 676
+++ + + PG + +DDG I + ++ + + +GG L RKGVN+P
Sbjct: 121 RVHLPHPELYAATAPGQSLLLDDGKIRLAVEAADPTAIVTRVVDGGPLSDRKGVNVPDAV 180
Query: 677 VDLPAVSEKDKSDLLFGVEQGVDMIFASFIR 769
+ +PA++EKD DL F + GVD I SF++
Sbjct: 181 IPIPALTEKDLRDLDFALSLGVDWIALSFVQ 211
>UniRef50_Q6F1U1 Cluster: Pyruvate kinase; n=10; Mollicutes|Rep:
Pyruvate kinase - Mesoplasma florum (Acholeplasma
florum)
Length = 478
Score = 115 bits (277), Expect = 1e-24
Identities = 69/206 (33%), Positives = 110/206 (53%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
++ + II T GP++ + ++ E GM R+NFSHG +E I ++ + +
Sbjct: 10 VKRTKIITTTGPSTNEPEQIRELFENGMTTIRLNFSHGDYEEQGYRIAGAKKVRE----E 65
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
LG P S I LDTKGPEIR G G EV + TI S ++ + + V Y
Sbjct: 66 LGKPVS--ILLDTKGPEIRVGKFVDG-KQEVTANQSITIYTDAESFKNKECLSGEMTVAY 122
Query: 515 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 694
+++ +K G+ I IDDG + + + V + N ++ + K VNLPG+ +P +
Sbjct: 123 -DMSVDLKIGDTILIDDGKLEMTVEEVKPGVVKAIAFNNHLVKTNKRVNLPGVDFSMPFL 181
Query: 695 SEKDKSDLLFGVEQGVDMIFASFIRN 772
++KD +D+ +GVEQGVD I ASF+ +
Sbjct: 182 AQKDINDIKYGVEQGVDYIAASFVNS 207
>UniRef50_O05118 Cluster: Pyruvate kinase; n=44; Proteobacteria|Rep:
Pyruvate kinase - Methylobacterium extorquens
(Protomonas extorquens)
Length = 483
Score = 115 bits (276), Expect = 2e-24
Identities = 68/204 (33%), Positives = 109/204 (53%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
R + I+ T+GPAS ++EK+ G +V R+N SH + E E I R E+ +
Sbjct: 10 RRTKIVATLGPASDTPEMIEKLFHAGADVFRINMSHLAREKLPERIEVIRTIEREGKRPI 69
Query: 338 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 517
G I +D +GP++R G G + L+ G+T L SD G+ D +++ +
Sbjct: 70 G------ILVDLQGPKLRLGTFVGDAAV---LENGQTFVL--DSD-PTPGDTDRVFLPHP 117
Query: 518 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 697
I + ++P + I IDDG + +I VS +E GG + +RKGV+LP + +PA++
Sbjct: 118 EILSALEPSHGILIDDGKLRLIVTEVSEGRAVTRVEVGGRISNRKGVSLPHTALPVPAMT 177
Query: 698 EKDKSDLLFGVEQGVDMIFASFIR 769
EKD+ DL G+ G D I SF++
Sbjct: 178 EKDRGDLEAGLAAGADWIAVSFVQ 201
>UniRef50_Q63P20 Cluster: Pyruvate kinase; n=74; Proteobacteria|Rep:
Pyruvate kinase - Burkholderia pseudomallei (Pseudomonas
pseudomallei)
Length = 484
Score = 113 bits (272), Expect = 5e-24
Identities = 63/204 (30%), Positives = 110/204 (53%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
R + I+ T+GP+S +E + G +V R+NFSHG+H HA +R+ A ++ A++
Sbjct: 13 RSTKIVATLGPSSSTETAIEALARAGADVFRLNFSHGTHADHA--LRHA--AVRAIEARI 68
Query: 338 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 517
G P + + LD +GP++R G G ++ KG G+A + + +
Sbjct: 69 GHP--IGVLLDLQGPKLRVGQFASG---RAQIAKGRPFVFDRDP---APGDARRVSLPHP 120
Query: 518 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 697
I + +PG+ + +DDG + +VS+ + T G++ RKGV++P + +PA+S
Sbjct: 121 EIFDAARPGHLLLVDDGKLRFRVDAVSSARIETTALLDGIVSDRKGVSVPDATLAIPALS 180
Query: 698 EKDKSDLLFGVEQGVDMIFASFIR 769
KD+ DL FG+ GVD + SF++
Sbjct: 181 AKDRDDLEFGLSLGVDWVALSFVQ 204
>UniRef50_Q2TSX0 Cluster: Pyruvate kinase; n=2; cellular
organisms|Rep: Pyruvate kinase - Phaeodactylum
tricornutum
Length = 665
Score = 112 bits (270), Expect = 8e-24
Identities = 64/202 (31%), Positives = 108/202 (53%)
Frame = +2
Query: 173 ICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 352
+ T+GPAS N ++EK+ G +V R+NFSHGS E E + RE E+ YS +G
Sbjct: 158 VVTLGPASSNKEMIEKLFLAGADVFRLNFSHGSQEQKKELLIMIREVEEKYSHPIG---- 213
Query: 353 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 532
I D +GP++R G +EL G++ +L + KG+ + + + I
Sbjct: 214 --ILGDLQGPKLRVGEFSKPEGEFLEL--GQSFRLDLDN---AKGDNKRVQLPHPEIIKA 266
Query: 533 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 712
+ G+ + +DDG + ++ + D L C ++ GM+ RKGVN P +++ ++ KD+S
Sbjct: 267 SELGHALLVDDGKVKLVVTAKGDDYLECRVDVAGMIKDRKGVNTPDSVLEISPLTPKDRS 326
Query: 713 DLLFGVEQGVDMIFASFIRNGA 778
DL + + GVD + SF++ A
Sbjct: 327 DLEYMLGIGVDWVALSFVQTPA 348
>UniRef50_UPI0000D56D72 Cluster: PREDICTED: similar to CG7070-PB,
isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG7070-PB, isoform B - Tribolium castaneum
Length = 535
Score = 109 bits (262), Expect = 8e-23
Identities = 61/200 (30%), Positives = 102/200 (51%)
Frame = +2
Query: 110 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 289
L+H+ L S+ RL+ I P ++ +E+ ++ GM VA + + + + E
Sbjct: 44 LEHLARLQEKSRVRRKRLTQFSVIIPPRI-SIEHIEEFLKAGMTVALIRMDYFTVDEIEE 102
Query: 290 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 469
+ R + K+G + +AI LD EI+TG L E+EL+KG+T K+
Sbjct: 103 MVAMIRNVVDDFGKKIGRVYPIAIGLDVSEQEIKTGKLLKP-LKEIELEKGQTTKIVAKP 161
Query: 470 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 649
++ + + + IYV+Y+NI +VVKPG+ + I D I + V+ D + C IE G+L
Sbjct: 162 EFANRVSKEFIYVNYENIADVVKPGDSLIIGDDNIRMSAIEVARDIINCIIEKAGLLTDN 221
Query: 650 KGVNLPGIPVDLPAVSEKDK 709
V LP +P+ LP +K
Sbjct: 222 LSVKLPNVPITLPKTESHEK 241
>UniRef50_Q9YEU2 Cluster: Pyruvate kinase; n=1; Aeropyrum
pernix|Rep: Pyruvate kinase - Aeropyrum pernix
Length = 458
Score = 109 bits (262), Expect = 8e-23
Identities = 65/201 (32%), Positives = 110/201 (54%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
I+ T+GP+S + ++L +M+ G++VAR+N SHG E + + R AE++ ++G
Sbjct: 7 IVATVGPSSSSASILAQMLSLGVDVARINASHGGVEQWNSMLESLRRAEEAVGKRVG--- 63
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
+A+D +GP +RTG S V+L+KG+ + L + E + VD +
Sbjct: 64 ---VAVDLEGPRVRTG-----NSEPVKLEKGDLVTL----GFME----GDVPVDARQFFE 107
Query: 530 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 709
+ G+ + +DDG I + +SV + + GG+LG RKGV + G DLP +S KD+
Sbjct: 108 TIDEGDIVLLDDGKIILQVESVEGFRVKARVLEGGVLGPRKGVVVRGKEPDLPPLSAKDR 167
Query: 710 SDLLFGVEQGVDMIFASFIRN 772
L F ++GV ++ SF R+
Sbjct: 168 RALEFFADKGVSHVYVSFARS 188
>UniRef50_Q8ZNW0 Cluster: Pyruvate kinase II; n=173;
Proteobacteria|Rep: Pyruvate kinase II - Salmonella
typhimurium
Length = 480
Score = 107 bits (257), Expect = 3e-22
Identities = 74/214 (34%), Positives = 110/214 (51%)
Frame = +2
Query: 146 SSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSY 325
S +R + I+ T+GPA+ LEK++ G NV RMNFSHGS E H RE
Sbjct: 2 SRRLRRTKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSPEDHKMRADKVREI---- 57
Query: 326 SAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIY 505
+AKLG +AI D +GP+IR + G +V L G+ L + E G+ + +
Sbjct: 58 AAKLGR--HVAILGDLQGPKIRVSTFKEG---KVFLNIGDKFLLDANLGKGE-GDKEKVG 111
Query: 506 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDL 685
+DYK + V PG+ + +DDG + + V + + GG L + KG+N G +
Sbjct: 112 IDYKGLPADVVPGDILLLDDGRVQLKVLEVQGMKVFTEVTVGGPLSNNKGINKLGGGLSA 171
Query: 686 PAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALH 787
A++EKDK+D+ GVD + SF R G L+
Sbjct: 172 EALTEKDKADIQTAALIGVDYLAVSFPRCGEDLN 205
>UniRef50_A1WED1 Cluster: Pyruvate kinase; n=1; Verminephrobacter
eiseniae EF01-2|Rep: Pyruvate kinase - Verminephrobacter
eiseniae (strain EF01-2)
Length = 496
Score = 106 bits (255), Expect = 5e-22
Identities = 67/205 (32%), Positives = 105/205 (51%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
R + I+ T+GPAS A+LE M+ G+NV R+NFSHG + H + R A +
Sbjct: 23 RATKIVATLGPASSEPALLEAMIRAGVNVVRLNFSHGKAQDHIDRAACVRAAAQR----- 77
Query: 338 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 517
+ +AI D +GP+IR G G V L G L S E G+ D + +DYK
Sbjct: 78 -AGHEVAIMADLQGPKIRVGKFAEG---RVLLAPGAPFVLDASRT--EPGDIDGVGLDYK 131
Query: 518 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 697
+ + VK G+ + ++DGLI + +V + + T++ GG L + KG+N G + A++
Sbjct: 132 ELPHDVKGGDLLLLNDGLIVLSVDAVRGEQVHTTVKIGGELSNNKGINKKGGGLTASALT 191
Query: 698 EKDKSDLLFGVEQGVDMIFASFIRN 772
KD D+ + D + SF +N
Sbjct: 192 AKDMEDIRTAMGFQADYVAVSFPKN 216
>UniRef50_A1IEN3 Cluster: Pyruvate kinase; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: Pyruvate kinase -
Candidatus Desulfococcus oleovorans Hxd3
Length = 478
Score = 105 bits (253), Expect = 1e-21
Identities = 60/204 (29%), Positives = 109/204 (53%), Gaps = 4/204 (1%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
+I TIGP SR+ AV+EK++ G+ + R+NFSH A+ I++ RE E+
Sbjct: 5 LIATIGPRSRDRAVIEKLVAVGVTIFRLNFSHAGPGDFADVIQSVREIEQQTGT------ 58
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
L + D GP+IR G + G A + + G+ ++L + G+A + ++ I
Sbjct: 59 ILTLMGDLSGPKIRIGEVAG---APLSVATGQLVRLGPARAKGAFGDALYLPLELAEILE 115
Query: 530 VVKPGNRIFIDDGL----ISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 697
+KPG + + DG+ + + + +N G++ S KG++ PG+ +DLPA++
Sbjct: 116 QLKPGAPVILSDGIPVFRVRKRLDTEAGPVFELETQNSGLVSSNKGISFPGLAIDLPALT 175
Query: 698 EKDKSDLLFGVEQGVDMIFASFIR 769
KD+SD+ ++ G+D + SF++
Sbjct: 176 AKDRSDVAAALDVGIDALALSFVQ 199
>UniRef50_Q0C0E8 Cluster: Pyruvate kinase; n=1; Hyphomonas neptunium
ATCC 15444|Rep: Pyruvate kinase - Hyphomonas neptunium
(strain ATCC 15444)
Length = 474
Score = 105 bits (251), Expect = 2e-21
Identities = 67/201 (33%), Positives = 111/201 (55%), Gaps = 1/201 (0%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
I+ T+GP SR+ + + E G++V R+NFSHG H H E ++ R AE A +G P
Sbjct: 13 IVATLGPGSRSPREVRALAEAGVDVFRLNFSHGEHAAHLEALKAVRAAE----AAVGWP- 67
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
LA D +GP++R G + GGS ++ +K I + ++ + +TI V + I
Sbjct: 68 -LATLADLQGPKVRVGKFD-GGSLKLGFRKEYRIIVGETAP-----DPETIPVPHAEIVA 120
Query: 530 VVKPGNRIFIDDG-LISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKD 706
+++ G+ I DDG LI + S + + G LG +KG + G + + A++EKD
Sbjct: 121 ILEEGDTILADDGKLIFTVISGGSEPRVRAEVP--GKLGDKKGFTVRGKALPVRALTEKD 178
Query: 707 KSDLLFGVEQGVDMIFASFIR 769
++DL F +E GVD++ SF++
Sbjct: 179 RADLDFALEIGVDIVALSFVQ 199
>UniRef50_Q40545 Cluster: Pyruvate kinase isozyme A, chloroplast
precursor; n=15; Magnoliophyta|Rep: Pyruvate kinase
isozyme A, chloroplast precursor - Nicotiana tabacum
(Common tobacco)
Length = 593
Score = 105 bits (251), Expect = 2e-21
Identities = 71/217 (32%), Positives = 108/217 (49%), Gaps = 8/217 (3%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
R + +ICTIGPA+ LE++ E GMNVAR+N HG+ E+H I R +
Sbjct: 114 RRTKLICTIGPATCGFEQLERLAEGGMNVARINMCHGTREWHRMVIERLRRLNEE----- 168
Query: 338 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 517
F++AI +DT+G EI G L G SA+ E GE T S + T+ V+Y
Sbjct: 169 -KGFAVAIMMDTEGSEIHMGDLGGASSAKAE--DGEIWNFTVRS-FDPPLPERTVTVNYD 224
Query: 518 NITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGMLGSRKGVNL--PGIPVD-- 682
VK G+ + +D G++ + + + D + C + G+L R + G V
Sbjct: 225 GFAEDVKVGDELLVDGGMVRFEVIEKIGPD-VKCLCTDPGLLLPRANLTFWRDGKLVRER 283
Query: 683 ---LPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAAL 784
LP +S KD D+ FG+ +GVD I SF+++ +
Sbjct: 284 NAMLPTISSKDWLDIDFGIAEGVDFIAVSFVKSAEVI 320
>UniRef50_Q7QVW2 Cluster: Pyruvate kinase; n=1; Giardia lamblia ATCC
50803|Rep: Pyruvate kinase - Giardia lamblia ATCC 50803
Length = 553
Score = 104 bits (249), Expect = 3e-21
Identities = 63/217 (29%), Positives = 111/217 (51%), Gaps = 2/217 (0%)
Frame = +2
Query: 134 IDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREA 313
+D + I CT+GP+S NV V+ M+ G ++ R+NFSHG+ + H + ++A
Sbjct: 30 VDKNHPHFNRVKICCTLGPSSFNVEVIAGMIRAGADIIRINFSHGNTDDHTQIFHKVQQA 89
Query: 314 EKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNA 493
+ K ++AI D +GP++R + +ELK+G+ L ++ G+
Sbjct: 90 -MQLTGK-----TVAIMGDIQGPKLRIAGFSNPDNC-IELKEGQEFTLDHNN---VNGDE 139
Query: 494 DTIYVDYKNITNVVKPGNRIFIDDGLISIICQSV--SADTLTCTIENGGMLGSRKGVNLP 667
+Y+ +K V +P + I ++DG I ++ SV A + ++ GG LG+RKG+ +P
Sbjct: 140 SRVYLPHKEFFAVCEPNDDIILNDGYIRLVATSVDRQAMRIVTRVKTGGKLGARKGITIP 199
Query: 668 GIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGA 778
+ L +S KD D+ G+D I SF++ A
Sbjct: 200 TRILPLSGLSPKDLGDIRNACRLGMDWIALSFVQTKA 236
>UniRef50_Q0PQH4 Cluster: Pyruvate kinase; n=1; Endoriftia
persephone 'Hot96_1+Hot96_2'|Rep: Pyruvate kinase -
Endoriftia persephone 'Hot96_1+Hot96_2'
Length = 246
Score = 103 bits (248), Expect = 4e-21
Identities = 59/204 (28%), Positives = 104/204 (50%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
R + I+ T+GPA+ + V++K++ G++V R+N SH H+ E R+ ++ ++
Sbjct: 36 RRTKIVATLGPATDDPKVMDKLIHAGVDVVRLNLSHDPHDQQRERAERIRDRSRASGRQV 95
Query: 338 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 517
G + D +GP+IR G + S V L++ L + G+ + + + Y
Sbjct: 96 G------VLCDLQGPKIRIGRFK---SDFVMLEEDGAFILDAECPLTD-GDDERVGLTYP 145
Query: 518 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 697
++ N V G+ + +DDG I + V + C + GG L + KG+N G + PA++
Sbjct: 146 DLINDVARGDTLLLDDGAIVLWIAEVEGKQVHCKVVVGGKLSNNKGINKQGGGLSAPALT 205
Query: 698 EKDKSDLLFGVEQGVDMIFASFIR 769
EKDK D+ F E D + SF+R
Sbjct: 206 EKDKQDIKFAAEIDADYLAVSFVR 229
>UniRef50_Q9WY51 Cluster: Pyruvate kinase; n=3; Thermotogaceae|Rep:
Pyruvate kinase - Thermotoga maritima
Length = 466
Score = 103 bits (248), Expect = 4e-21
Identities = 62/205 (30%), Positives = 109/205 (53%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
+R + I+CT+GP + + ++EKM++ G+NV R+N SHG + I ++ + K
Sbjct: 1 MRSTKIVCTVGPRTDSYEMIEKMIDLGVNVFRINTSHGDWNEQEQKILKIKDLRE----K 56
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
P +AI +D GP+IRTG LE VELK+G+ LTT + GN + V+
Sbjct: 57 KKKP--VAILIDLAGPKIRTGYLE---KEFVELKEGQIFTLTTK---EILGNEHIVSVNL 108
Query: 515 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 694
++ VK G+ I + DG I + + + ++ GG + R+GVN+P + + ++
Sbjct: 109 SSLPKDVKKGDTILLSDGEIVLEVIETTDTEVKTVVKVGGKITHRRGVNVPTADLSVESI 168
Query: 695 SEKDKSDLLFGVEQGVDMIFASFIR 769
+++D+ + G V+ SF+R
Sbjct: 169 TDRDREFIKLGTLHDVEFFALSFVR 193
>UniRef50_O51323 Cluster: Pyruvate kinase; n=5; cellular
organisms|Rep: Pyruvate kinase - Borrelia burgdorferi
(Lyme disease spirochete)
Length = 477
Score = 102 bits (245), Expect = 9e-21
Identities = 63/205 (30%), Positives = 105/205 (51%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
+L+ I+ TI ++ + + G+NV R+N +H SHE + I N R+
Sbjct: 4 KLTKIVATISDLRCEPEHIKDLHDAGVNVIRLNTAHQSHEDTIKVIDNVRKISNK----- 58
Query: 338 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 517
+A+ +DTKGPE+RT +E + +K G+ + ++TS E N T +Y
Sbjct: 59 -----IALMIDTKGPEVRTANIEN----PIIVKTGDKVIISTSP-INEPNNFQT---NYD 105
Query: 518 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 697
V G+++ IDDG + + + D L C I+N G + ++K +N PGI + L +V+
Sbjct: 106 GFVKEVPQGSKVLIDDGELEMTVVAKLPDRLICEIKNDGQIKNKKSINTPGISLKLQSVT 165
Query: 698 EKDKSDLLFGVEQGVDMIFASFIRN 772
EKDK + + VD I SF+R+
Sbjct: 166 EKDKGFIELAAKYNVDFIAHSFVRH 190
>UniRef50_Q7P1G4 Cluster: Pyruvate kinase; n=4; Bacteria|Rep:
Pyruvate kinase - Chromobacterium violaceum
Length = 468
Score = 102 bits (244), Expect = 1e-20
Identities = 57/208 (27%), Positives = 105/208 (50%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
+R + I+ T+GP+S + ++ +G+N+ R+N SHGSH+ H + R AEK+
Sbjct: 2 LRNTKILATLGPSSSAPEKILELARSGVNIFRLNMSHGSHDDHRARLAAIRAAEKTLDRP 61
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
+G + +D +GP++R G +K G+ + + +GNA+ + +
Sbjct: 62 IG------VLVDLQGPKLRIGKFP----QPTTVKTGDRYEFVLD---ETEGNAERATLPH 108
Query: 515 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 694
++PG+ I ++DG ++ + + + GG L S KG NLP + L A+
Sbjct: 109 PEAFEALEPGHLILVNDGKLAFEVAEMHPRRIVTRVTVGGELSSNKGFNLPHTVLPLSAI 168
Query: 695 SEKDKSDLLFGVEQGVDMIFASFIRNGA 778
+ KD+ D F +E+G D + SF++ A
Sbjct: 169 TGKDRKDAEFALEEGADWVAMSFVQTAA 196
>UniRef50_Q1MPC8 Cluster: Pyruvate kinase; n=4;
Desulfovibrionaceae|Rep: Pyruvate kinase - Lawsonia
intracellularis (strain PHE/MN1-00)
Length = 471
Score = 101 bits (243), Expect = 2e-20
Identities = 64/204 (31%), Positives = 107/204 (52%), Gaps = 3/204 (1%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
II TIGPAS + L ++++ G+++ R+NFSHG E I RE E +
Sbjct: 5 IIATIGPASNSKETLSQLIQAGVSIFRLNFSHGDSSAFIELISTIRELEHIHQ------I 58
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYV--DYKNI 523
+ I D GP+IR G L G + + KG+ + L ++K D Y+ D+K I
Sbjct: 59 PITIMQDLSGPKIRIGALPG--DVALNVSKGDVLCLGP----EDKRTNDYPYIPFDHKAI 112
Query: 524 TNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 700
+ + + + + DG + + + S T + G++ SRKG+ LPG + +PA++E
Sbjct: 113 LSDLVVNDILILADGTLQFQVKEQNSNGTFLLIAQEDGIITSRKGLALPGKSIKVPAITE 172
Query: 701 KDKSDLLFGVEQGVDMIFASFIRN 772
KD+ DL G++ GVD + SF+++
Sbjct: 173 KDQKDLSDGLKLGVDAVAISFVQS 196
>UniRef50_Q07637 Cluster: Pyruvate kinase; n=44;
Streptococcaceae|Rep: Pyruvate kinase - Lactococcus
lactis subsp. lactis (Streptococcus lactis)
Length = 502
Score = 101 bits (241), Expect = 3e-20
Identities = 65/198 (32%), Positives = 101/198 (51%), Gaps = 5/198 (2%)
Frame = +2
Query: 191 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 370
+++N+A L +E G NV R NFSHG H + AE+ K+G LD
Sbjct: 38 SAKNIAAL---IEEGANVFRFNFSHGDHPEQGARMATVHRAEEIAGHKVG------FLLD 88
Query: 371 TKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYV-DYKNITNVVKPGN 547
TKGPE+RT L G A + + G+ ++ T + + V +I + V+ G
Sbjct: 89 TKGPEMRTELFADGADA-ISVVTGDKFRVATKQGLKSTPELIALNVAGGLDIFDDVEIGQ 147
Query: 548 RIFIDDGLISIICQSVSADTLTCTIE--NGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLL 721
I IDDG + + A T +E N G++G +KGVN+P + PA++E+D +D+
Sbjct: 148 TILIDDGKLGLSLTGKDAATREFEVEAQNDGVIGKQKGVNIPNTKIPFPALAERDDADIR 207
Query: 722 FGVEQ--GVDMIFASFIR 769
FG+ Q G++ I SF+R
Sbjct: 208 FGLSQPGGINFIAISFVR 225
>UniRef50_Q5ZZ75 Cluster: Pyruvate kinase II; n=4; Legionella
pneumophila|Rep: Pyruvate kinase II - Legionella
pneumophila subsp. pneumophila (strain Philadelphia 1
/ATCC 33152 / DSM 7513)
Length = 474
Score = 100 bits (240), Expect = 4e-20
Identities = 62/206 (30%), Positives = 107/206 (51%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
+R + I+ T+GPAS+ +L M+ G+NV R+NFSH + I R+ + +
Sbjct: 2 LRRTKIVATLGPASKEPEILRSMLAAGVNVVRINFSHADSSA-LQLIALVRKI----ADE 56
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
L P +A+ D +GP+IR G + + + L G+ L + G+ + + V Y
Sbjct: 57 LNHP--VAVMADLQGPKIRVGRFQ---NKSITLIDGQNFTLDCMAP-DTLGDINGVSVAY 110
Query: 515 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 694
N+ N + G+ + I+DGLI + +S + C + GG+L KG+N G + +
Sbjct: 111 PNLANELSIGDHLLINDGLIELEVIEISGSKIHCKVVEGGVLTDLKGLNRKGGGLAARTL 170
Query: 695 SEKDKSDLLFGVEQGVDMIFASFIRN 772
+EKD++DL +E VD I SF+++
Sbjct: 171 TEKDRNDLRTAIEAEVDYISLSFVKD 196
>UniRef50_A7PC98 Cluster: Chromosome chr2 scaffold_11, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr2 scaffold_11, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 475
Score = 100 bits (239), Expect = 5e-20
Identities = 56/168 (33%), Positives = 93/168 (55%)
Frame = +2
Query: 260 SHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKK 439
SHG H H +TI +E + K+ +AI LDTKGPE+R+G + + LK+
Sbjct: 2 SHGDHASHKKTIDLVKEYNAQFEDKV-----IAIMLDTKGPEVRSGDVP----KPIMLKE 52
Query: 440 GETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCT 619
G+ T + +T+ V+Y + N V+ G+ + +D G++S++ +S S D + C
Sbjct: 53 GQEFNFTIKRGVSSE---NTVSVNYDDFVNDVEVGDILLVDGGMMSLVVKSKSKDLVKCQ 109
Query: 620 IENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASF 763
+ +GG L SR+ +N+ G LP++++KD D+ FGV+ VD SF
Sbjct: 110 VIDGGELKSRRHLNVRGKSATLPSITDKDWEDIKFGVDNQVDFYAVSF 157
>UniRef50_P78031 Cluster: Pyruvate kinase; n=6; Mycoplasma|Rep:
Pyruvate kinase - Mycoplasma pneumoniae
Length = 508
Score = 99.5 bits (237), Expect = 8e-20
Identities = 63/190 (33%), Positives = 98/190 (51%), Gaps = 3/190 (1%)
Frame = +2
Query: 206 AVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPE 385
A +E +++ G+ V R+NFSHG+HE A I+ R+ K KL P S I LDT GPE
Sbjct: 42 ANIENIIKNGVTVIRLNFSHGNHEEQAVRIKIVRDVAK----KLNLPVS--IMLDTNGPE 95
Query: 386 IRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK-NITNVVKPGNRIFID 562
IR + E LK E + TT+ + + N+ N VK G +I +D
Sbjct: 96 IR--VFETAPEGLKILKDSEVVINTTTKEVAKNNQFSVSDASGTYNMVNDVKVGQKILVD 153
Query: 563 DGLISIICQSVSA--DTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQ 736
DG +S++ + + + + C +N + ++K +NLP +P +S KD D+ FG+
Sbjct: 154 DGKLSLVVKRIDTKNNQVICVAQNDHTIFTKKRLNLPNADYSIPFLSAKDLRDIDFGLTH 213
Query: 737 GVDMIFASFI 766
+D I ASF+
Sbjct: 214 QIDYIAASFV 223
>UniRef50_A7APT5 Cluster: Pyruvate kinase family protein; n=1;
Babesia bovis|Rep: Pyruvate kinase family protein -
Babesia bovis
Length = 693
Score = 99.1 bits (236), Expect = 1e-19
Identities = 65/226 (28%), Positives = 112/226 (49%), Gaps = 17/226 (7%)
Frame = +2
Query: 143 KSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKS 322
+ ++ L+ + T+GP++ L +ME G ++ R+NFSHG+ + R R+ E
Sbjct: 105 QGQFMTLTKQVSTLGPSTCTADSLRSIMEAGTDIYRLNFSHGTRLFKLRLTRMIRQLELV 164
Query: 323 YSAKLGSPFSLA----IALDTKGPEIRTGL-----------LEGGGSAEVELKKGETIKL 457
S+ GS + I D +GP++R G +E + VELKKG+
Sbjct: 165 RSSGEGSDSFMVSPKGILGDIQGPKLRIGRFMPNVDAVGKGIESSAAEFVELKKGDKFTF 224
Query: 458 TTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSAD--TLTCTIENG 631
T + KG+ + ++ +I + GN I +DDG +++ SV D ++T + N
Sbjct: 225 DT---HDVKGSQTRVRFNFPDILRDLNVGNTIAMDDGNLNLEVISVDRDAPSVTAVVLND 281
Query: 632 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIR 769
G+L SRKG +P + + + SEKD D +F G+D + SF++
Sbjct: 282 GVLSSRKGFAVPNVAITVDLFSEKDVKDTIFSYALGLDFLGVSFVQ 327
>UniRef50_Q8EWX2 Cluster: Pyruvate kinase; n=1; Mycoplasma
penetrans|Rep: Pyruvate kinase - Mycoplasma penetrans
Length = 498
Score = 98.7 bits (235), Expect = 1e-19
Identities = 65/204 (31%), Positives = 101/204 (49%), Gaps = 6/204 (2%)
Frame = +2
Query: 182 IGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAI 361
I A +N+A L + G+NV R NFSHG +E + RE K + +
Sbjct: 36 IETAKKNLAAL---FDAGVNVVRFNFSHGDYEEQTIRLNLVREVAKEKGVNIST------ 86
Query: 362 ALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYV----DYKNITN 529
LDTKGPEIR + EVE+K +++ T+ +E G ++ V N+
Sbjct: 87 MLDTKGPEIR---VYKTSEKEVEIKSDSKVRIYTTK--KEIGTSEKFSVLDSTGTYNMAK 141
Query: 530 VVKPGNRIFIDDGLIS--IICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEK 703
V+PGN IF+DDG + +I +V + N +L K +NLP +P +S+K
Sbjct: 142 DVQPGNTIFVDDGKLKLEVISSNVEEGIIETIARNTWILRENKRINLPDSNYSIPFMSDK 201
Query: 704 DKSDLLFGVEQGVDMIFASFIRNG 775
D++D++F ++ D I ASF+ G
Sbjct: 202 DRNDIIFAIKNKFDYIAASFVNTG 225
>UniRef50_Q9PF54 Cluster: Pyruvate kinase; n=11;
Xanthomonadaceae|Rep: Pyruvate kinase - Xylella
fastidiosa
Length = 501
Score = 98.3 bits (234), Expect = 2e-19
Identities = 64/210 (30%), Positives = 99/210 (47%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
R + I+ T+GPA+ VL+ + + G+NV R+NFSHG A R A ++
Sbjct: 19 RRTRILATLGPATDPPGVLDALFKAGVNVVRLNFSHGDASDQARRAAEVRAAAAHVGVEI 78
Query: 338 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 517
G I D GP+IR G G +V L L S+ G+A + V Y
Sbjct: 79 G------ILADLPGPKIRIGRFTEG---KVRLVADARFDLLADSN-APLGDATQVGVSYL 128
Query: 518 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 697
+ V G+ + +DDGL+ + V + T+ N G+L RKG+N G + L A++
Sbjct: 129 GLPQDVAAGDVLLLDDGLMQLQVVQVQGARIVTTVLNDGVLSDRKGLNKQGGGLSLGALT 188
Query: 698 EKDKSDLLFGVEQGVDMIFASFIRNGAALH 787
++D+ + GVD I SF R+ +H
Sbjct: 189 DRDRELIGIVSRMGVDFIAVSFCRHAEEMH 218
>UniRef50_A3ZTM3 Cluster: Pyruvate kinase; n=1; Blastopirellula
marina DSM 3645|Rep: Pyruvate kinase - Blastopirellula
marina DSM 3645
Length = 490
Score = 97.9 bits (233), Expect = 3e-19
Identities = 58/200 (29%), Positives = 105/200 (52%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
I+ T+GPA +LE+M+ G++V R+N +HG + H+ RE S +L P
Sbjct: 15 IVATVGPACNTPEMLEQMILAGVDVFRLNLAHGELDEHSRVATTIREI----SERLKRP- 69
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
+A D GP+IR G L VE + I+ +++ E + +Y+ + +
Sbjct: 70 -VATLADLSGPKIRLGTLVQDPIYCVEEQMYRFIRGDVATEPNE------LVSNYEPLID 122
Query: 530 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 709
VK G+ + + DG I++ + D++TC + GG+L SR+G+NLPG + + ++ +D+
Sbjct: 123 EVKVGDNVMLADGTITMEVVEKTEDSVTCVVVAGGILRSRQGINLPGTKLGVETITPRDR 182
Query: 710 SDLLFGVEQGVDMIFASFIR 769
+ + E +D + SF+R
Sbjct: 183 DHIRWAAETDLDYVSLSFVR 202
>UniRef50_Q1ZJ78 Cluster: Pyruvate kinase; n=1; Psychromonas sp.
CNPT3|Rep: Pyruvate kinase - Psychromonas sp. CNPT3
Length = 485
Score = 97.5 bits (232), Expect = 3e-19
Identities = 63/208 (30%), Positives = 107/208 (51%), Gaps = 2/208 (0%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
II T+GPAS++ ++ K++ G+N+ R+NFSHGS + H + C + + SA+LG
Sbjct: 6 IIATLGPASQSEDMIRKLILAGVNIVRLNFSHGSAQEHID----CAKLVRRISAELGK-- 59
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
+ + +D +GP+IR + + VEL G+ L + G+ + + Y ++
Sbjct: 60 YVGVLVDLQGPKIRIACFK---NDVVELVAGQRFVLDAKL-AEFDGSVSAVGLGYPDLIA 115
Query: 530 VVKPGNRIFIDDGLISIICQSVSADTL--TCTIENGGMLGSRKGVNLPGIPVDLPAVSEK 703
+ + + +DDG I + VS + L T + N G L +RKG+NL G + PA++ K
Sbjct: 116 DLNIDDVLLLDDGRIHLQVTEVSKEELKVTTKVLNSGKLSNRKGINLLGGGLSAPALTPK 175
Query: 704 DKSDLLFGVEQGVDMIFASFIRNGAALH 787
D D+ D + SF RN +H
Sbjct: 176 DIEDMSTAALLNADFLAISFPRNAQDIH 203
>UniRef50_Q8IJ37 Cluster: Pyruvate kinase; n=7; Plasmodium|Rep:
Pyruvate kinase - Plasmodium falciparum (isolate 3D7)
Length = 745
Score = 97.5 bits (232), Expect = 3e-19
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 13/212 (6%)
Frame = +2
Query: 173 ICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 352
I TIGPAS N LEK+ G++V R+NFSHG I + R EK Y +G
Sbjct: 102 IATIGPASENFEQLEKLYLNGIDVFRLNFSHGLKSIKKYIINSIRILEKKYDTTIG---- 157
Query: 353 LAIALDTKGPEIRTG------LLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
I D +GP+IR G + E + VELK+G+ + GN + + ++Y
Sbjct: 158 --ILGDIQGPKIRIGEFEKNQINENDNNTFVELKEGDLFSFDLMNSL---GNQNRVQLNY 212
Query: 515 KNITNVVKPGNRIFIDDGLISIICQSVSADT-------LTCTIENGGMLGSRKGVNLPGI 673
+ K G I +DDG + + + DT + + GG L S+KG +P +
Sbjct: 213 PELIKNAKAGQIILLDDGNLKMKILENNYDTSNIQNSYIKVQVLTGGKLYSKKGFCIPNM 272
Query: 674 PVDLPAVSEKDKSDLLFGVEQGVDMIFASFIR 769
+ + +SEKD D+LF + + VD + SF++
Sbjct: 273 IMPIDVLSEKDIKDILFCINEEVDFLGYSFVQ 304
>UniRef50_Q04668 Cluster: Pyruvate kinase; n=2; Leishmania
braziliensis|Rep: Pyruvate kinase - Leishmania
braziliensis
Length = 91
Score = 97.5 bits (232), Expect = 3e-19
Identities = 54/99 (54%), Positives = 72/99 (72%), Gaps = 1/99 (1%)
Frame = +2
Query: 104 SQLQHMCGLDIDSKSSYIRLSG-IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEY 280
SQL H L I +R +G I+CTIGP++++V L+ ++++GM+VARMNFSHGSHEY
Sbjct: 2 SQLAHNLTLSIFEP---LRTTGTIVCTIGPSTQSVEALKGLIKSGMSVARMNFSHGSHEY 58
Query: 281 HAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTG 397
H TI N R+A +A+LG ++AIALDTKGPEIRTG
Sbjct: 59 HQTTINNVRQA----AAELG--VNIAIALDTKGPEIRTG 91
>UniRef50_UPI0000E481DE Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 461
Score = 96.3 bits (229), Expect = 8e-19
Identities = 45/64 (70%), Positives = 50/64 (78%)
Frame = +2
Query: 596 SADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNG 775
SAD L C I NGGMLGSRKGVNLP VDLPA+SEKDK DL FG+E GV+M+FASFIR
Sbjct: 117 SADYLDCKIINGGMLGSRKGVNLPNAEVDLPALSEKDKGDLRFGLEHGVEMVFASFIRKA 176
Query: 776 AALH 787
+H
Sbjct: 177 TDVH 180
>UniRef50_Q94KE3 Cluster: Pyruvate kinase; n=25; Magnoliophyta|Rep:
Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress)
Length = 527
Score = 95.1 bits (226), Expect = 2e-18
Identities = 67/222 (30%), Positives = 116/222 (52%), Gaps = 11/222 (4%)
Frame = +2
Query: 140 SKSSYI-RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAE 316
SKSS+ L+ I+ T+GP SR+V L ++ GM+VAR +FS G +YH ET+ N + A
Sbjct: 21 SKSSFFPALTKIVGTLGPKSRSVEALSGCLKAGMSVARFDFSWGDADYHQETLDNLKVAV 80
Query: 317 KSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNAD 496
+S + KL A+ LDT GPE++ + + LK + LT + D ++ +++
Sbjct: 81 RS-TKKL-----CAVMLDTVGPELQ---VINKSEKAITLKADGLVTLTPNQD--QEASSE 129
Query: 497 TIYVDYKNITNVVKPGNRIFIDDGLIS--------IICQSVSADTLTCTIENGGML-GSR 649
+ +++ + VK G+ IF+ L + + V D + C N L GS
Sbjct: 130 VLPINFNGLAKAVKKGDTIFVGQYLFTGSETTSVWLEVDEVKGDDVICLSRNAATLAGSL 189
Query: 650 KGVNLPGIPVDLPAVSEKDKSDL-LFGVEQGVDMIFASFIRN 772
++ + +DLP ++EKDK + +GV+ +D + S+ R+
Sbjct: 190 FTLHSSQVHIDLPTLTEKDKEVISTWGVQNKIDFLSLSYCRH 231
>UniRef50_A7QH42 Cluster: Chromosome chr3 scaffold_95, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr3 scaffold_95, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 573
Score = 93.9 bits (223), Expect = 4e-18
Identities = 60/216 (27%), Positives = 111/216 (51%), Gaps = 6/216 (2%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
+R + ++CTIGPA + LE + +GMNVAR+N H + E+H + IR + +
Sbjct: 87 MRKTKLVCTIGPACCLLEDLENLASSGMNVARLNMCHNTWEWHRDVIRKIKRLNEE---- 142
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
+ +++ +DT+G +I +++ G V+ + E+I L T+ + E T+ +Y
Sbjct: 143 --KGYCVSVMIDTEGGQIH--VVDHGAPFSVK-AENESIWLFTTQKF-EGSRPFTVQANY 196
Query: 515 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVN------LPGIP 676
+ + + G+ + ID G+ S + L C + G+L R ++ L
Sbjct: 197 EGFSEGITVGDEVVIDGGMASFEVIEKIGNDLRCKCTDPGLLLPRAKLSFWRDGKLVEKN 256
Query: 677 VDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAAL 784
+LP +S KD +D+ FG+ +GVD I SF+++ A+
Sbjct: 257 YELPTISTKDWADIEFGISEGVDFIAMSFVKDANAI 292
>UniRef50_Q4N603 Cluster: Pyruvate kinase; n=2; Theileria|Rep:
Pyruvate kinase - Theileria parva
Length = 699
Score = 92.3 bits (219), Expect = 1e-17
Identities = 67/225 (29%), Positives = 115/225 (51%), Gaps = 19/225 (8%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSH-EYH--AETIRNCR--EAEK 319
+ L+ + T+GPA+ N ++ + + G++V R+NFSH S H ++TIR E K
Sbjct: 116 LTLTKQVATLGPATNNAESIKSLFDAGVDVFRLNFSHDSRLSKHLVSKTIRQLEINEPPK 175
Query: 320 SYSAKLGSPFS-LAIALDTKGPEIRTG----------LLEGGGSAE-VELKKGETIKLTT 463
+Y +I D +GP++R G +L G E VELK G+ L T
Sbjct: 176 NYPFNGDHVVEHKSILGDIQGPKLRIGKFMPNLDVPGVLPGSKGCEFVELKAGD---LFT 232
Query: 464 SSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSAD--TLTCTIENGGM 637
Y G+ + +D+ I +K G++I +DDG +S+ + + ++T ++N
Sbjct: 233 FDAYDVLGSKSRVQLDFPEILKELKVGDKILLDDGNLSMTVVKTNPEEPSVTAEVKNDYK 292
Query: 638 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRN 772
L SRKG ++P + + + + EKD D +F + GVD + SF++N
Sbjct: 293 LSSRKGFSVPKVVLPIEFLDEKDVKDAIFCLGIGVDFLGVSFVQN 337
>UniRef50_Q0AHE3 Cluster: Pyruvate kinase; n=2;
Nitrosomonadaceae|Rep: Pyruvate kinase - Nitrosomonas
eutropha (strain C71)
Length = 483
Score = 91.5 bits (217), Expect = 2e-17
Identities = 59/202 (29%), Positives = 100/202 (49%), Gaps = 1/202 (0%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGM-NVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSP 346
IICT+GPA+ VL +++ GM +VAR N SHG H HA I+ R+ A+
Sbjct: 19 IICTLGPATDQPGVLARLIGAGMMDVARFNLSHGDHASHARRIQQVRQL-----AQQAGR 73
Query: 347 FSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNIT 526
F +A+ +D GP+ R G L G EL G + L +D D + V + +
Sbjct: 74 F-IAVLMDLPGPKFRLGELSNGAR---ELHLGADVILALEAD-----PPDGLPVKHPALL 124
Query: 527 NVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKD 706
++ G +++ DG I + + A+ + C + G + S G+N+P + ++ D
Sbjct: 125 QALRVGESVYLADGAIRLEVKIAGAERVVCQVLVSGTVTSGSGINVPESKRSVLIPTDDD 184
Query: 707 KSDLLFGVEQGVDMIFASFIRN 772
+ L+F +EQ + I SF+++
Sbjct: 185 RRHLVFALEQQAEWIGVSFVQS 206
>UniRef50_P32044 Cluster: Pyruvate kinase; n=2; Thermoplasma|Rep:
Pyruvate kinase - Thermoplasma acidophilum
Length = 544
Score = 89.8 bits (213), Expect = 7e-17
Identities = 57/200 (28%), Positives = 105/200 (52%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
I+ TIGPAS + ++++M++ G+++ R+N +H + + + +S + +G
Sbjct: 5 IVATIGPASSSPEIMKQMIDNGLSLVRINSAHAD----IKDVSKITQMVRSINRDVG--- 57
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
I +D KGPE+RTG GG T+K+++ DY I ++ N+ +
Sbjct: 58 ---IMIDLKGPELRTGEFAGG-----------TLKISSGKDYVM---GKDIVLNNMNVLS 100
Query: 530 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 709
V+ G+RI + DG +S +S D T N G+L R VN+PG ++L ++++D+
Sbjct: 101 AVQVGDRILMSDGEVSFEVEST--DPFTIRALNDGVLRDRSRVNIPGRFIELGTITDRDR 158
Query: 710 SDLLFGVEQGVDMIFASFIR 769
+ + G+ GVD SF++
Sbjct: 159 AFIREGIADGVDFFALSFVQ 178
>UniRef50_Q5C2V0 Cluster: Pyruvate kinase; n=1; Schistosoma
japonicum|Rep: Pyruvate kinase - Schistosoma japonicum
(Blood fluke)
Length = 168
Score = 89.0 bits (211), Expect = 1e-16
Identities = 44/136 (32%), Positives = 80/136 (58%)
Frame = +2
Query: 104 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 283
S +QH+ ID ++R + ++CT+G + +++M+++GMN+ R+N S G+ E +
Sbjct: 25 SLMQHISNQSIDHAPFFVRHTNLVCTLGDHWDSDEKIDQMIKSGMNILRLNLSMGTKEKY 84
Query: 284 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 463
AE IR R E+SY +P S+ IALD P +RTGL+ A V ++ G+ + LT
Sbjct: 85 AEVIRRVRRLEESYDY---NP-SVGIALDLSAPPVRTGLINESVDAVVVIQTGQMVTLTI 140
Query: 464 SSDYQEKGNADTIYVD 511
+ +Y++ + I+++
Sbjct: 141 NDEYEKNTTSSIIWIN 156
>UniRef50_UPI0000DA20CA Cluster: PREDICTED: similar to Pyruvate
kinase isozyme M2; n=4; Rattus norvegicus|Rep:
PREDICTED: similar to Pyruvate kinase isozyme M2 -
Rattus norvegicus
Length = 123
Score = 88.6 bits (210), Expect = 2e-16
Identities = 44/89 (49%), Positives = 62/89 (69%)
Frame = +2
Query: 110 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 289
L+HMC L+IDS +GIICTIG ++V +L+ M+ +GMNVA +NFSHG+HEYHAE
Sbjct: 27 LEHMCCLEIDSAPIMAHNTGIICTIG---QSVEMLKGMIMSGMNVAHLNFSHGTHEYHAE 83
Query: 290 TIRNCREAEKSYSAKLGSPFSLAIALDTK 376
TI+N +S+++ S+ +ALDTK
Sbjct: 84 TIKNVCATTESFASDPILYLSIVVALDTK 112
>UniRef50_Q9VFG4 Cluster: Pyruvate kinase; n=3; Sophophora|Rep:
Pyruvate kinase - Drosophila melanogaster (Fruit fly)
Length = 1010
Score = 85.0 bits (201), Expect = 2e-15
Identities = 42/95 (44%), Positives = 59/95 (62%)
Frame = +2
Query: 104 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 283
SQL + L + + + L+ IICTIGP+S VL ++ GM V R++FS G+H+ H
Sbjct: 165 SQLDYQSRLQFQAPALRLPLTSIICTIGPSSSQPEVLLNLIHAGMKVVRLDFSDGTHDCH 224
Query: 284 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEI 388
+ I+ R+A Y+ + G P SLAIALDTKGP I
Sbjct: 225 CQAIQAARKAIAMYAEETGLPRSLAIALDTKGPVI 259
Score = 54.4 bits (125), Expect = 3e-06
Identities = 25/43 (58%), Positives = 32/43 (74%)
Frame = +2
Query: 656 VNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAAL 784
+N G+ DL A++E+DK DL FG +Q VDMIFASFIR+ AL
Sbjct: 259 INPQGVAADLNAITEQDKLDLKFGADQKVDMIFASFIRDAKAL 301
>UniRef50_A3DMY9 Cluster: Pyruvate kinase; n=1; Staphylothermus
marinus F1|Rep: Pyruvate kinase - Staphylothermus
marinus (strain ATCC 43588 / DSM 3639 / F1)
Length = 469
Score = 85.0 bits (201), Expect = 2e-15
Identities = 57/203 (28%), Positives = 102/203 (50%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
II TIGP+S VL ++++ G++ R+NFSHG+ E ++ RE + Y +
Sbjct: 6 IITTIGPSSGKYEVLSRLIQEGVDGFRINFSHGNPHEWDEWVKMVRELAEKYERE----- 60
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
++I D GP++R G L E+K +T+KL E+ +TI V + +
Sbjct: 61 -ISIMGDLPGPQVRIGEL-----PVQEIKAKQTVKLVYKDKVDEE---NTIPVPNRKVFE 111
Query: 530 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 709
+++ G+ + IDDG I + + + + N +L K + + G +DLP +SEKD
Sbjct: 112 ILELGDIVLIDDGKIILRIIDIGGNEAEAIVLNDAVLYPHKTLVVFGKEIDLPVLSEKDV 171
Query: 710 SDLLFGVEQGVDMIFASFIRNGA 778
+ + V + + + SF+R +
Sbjct: 172 DLVNYSVSRKLTYLAISFVRRSS 194
>UniRef50_Q6L281 Cluster: Pyruvate kinase; n=2;
Thermoplasmatales|Rep: Pyruvate kinase - Picrophilus
torridus
Length = 555
Score = 84.6 bits (200), Expect = 3e-15
Identities = 55/201 (27%), Positives = 103/201 (51%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
+I TIGPAS ++ +++KM G++ R+N +H + Y + + + KS +G
Sbjct: 6 LIATIGPASESMEIIKKMANLGLSCIRINTAHIENGYITKVAKMVDDVNKSEGTYIG--- 62
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
+ +D KGPE+RTG + G S +++ K I Y + N D I ++Y NI++
Sbjct: 63 ---LMVDLKGPELRTGKFKDG-SFKIDYNKKYKIS------YNKNDNPD-ILINY-NISD 110
Query: 530 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 709
+ I + DG + SV+ D + T + G L VN+PG + L +++++D+
Sbjct: 111 FIDDKTLIAMSDGKLRFSVDSVNGDIINVTSLDSGSLRDNSRVNVPGKLLRLGSLTDRDR 170
Query: 710 SDLLFGVEQGVDMIFASFIRN 772
+ G++ V+ SF+++
Sbjct: 171 MFIEEGIKNNVNFYALSFVQS 191
>UniRef50_Q5IX04 Cluster: Pyruvate kinase; n=1; Prototheca
wickerhamii|Rep: Pyruvate kinase - Prototheca
wickerhamii
Length = 259
Score = 83.4 bits (197), Expect = 6e-15
Identities = 53/147 (36%), Positives = 84/147 (57%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
R + +CTIGP S + ++ + GMNV R+N SHG H H + I RE Y+A L
Sbjct: 100 RKTKTVCTIGPTSCDREAFFRLADAGMNVVRLNMSHGDHASHQQVIDLVRE----YNA-L 154
Query: 338 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 517
G +LAI LDTKGPE+R+G L + ++L+KG+ I T + G + I V+Y
Sbjct: 155 GRR-NLAIMLDTKGPEVRSGDL----TQPLDLEKGDLITFTIVAG--ADGTNNRIGVNYD 207
Query: 518 NITNVVKPGNRIFIDDGLISIICQSVS 598
+ V+ G+ + +D G+++++ +S S
Sbjct: 208 GFIDDVEVGDMLLVDGGIMTMLVKSKS 234
>UniRef50_A3ALA5 Cluster: Pyruvate kinase; n=3; Oryza sativa|Rep:
Pyruvate kinase - Oryza sativa subsp. japonica (Rice)
Length = 548
Score = 83.0 bits (196), Expect = 8e-15
Identities = 59/213 (27%), Positives = 108/213 (50%), Gaps = 7/213 (3%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
+R + ++CT+GPA V L + GM VAR+N HG +H +R R +
Sbjct: 62 LRKTKLVCTVGPAC--VGALPALARGGMGVARVNLCHGGRGWHRAVMREVRRLNEEEG-- 117
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
F +++ +DT+G ++ + GG+A V+ + G T S ++ + T++V++
Sbjct: 118 ----FCVSLMVDTEGSQLLVA--DHGGAASVKAEDGSEWLFT--SKRTDESHPFTMHVNF 169
Query: 515 KNITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGMLGSRKGVNL--PGIPVD- 682
+ + G+ + ID G+ + + + V D L C + G+L R ++ G V+
Sbjct: 170 DKFSEDILVGDELVIDGGMATFEVIEKVGND-LRCKCTDPGLLLPRAKLSFWRNGKLVER 228
Query: 683 ---LPAVSEKDKSDLLFGVEQGVDMIFASFIRN 772
LP +S KD +D+ FG+ +GVD I SF+++
Sbjct: 229 NFGLPTLSAKDWADIEFGIAEGVDCIALSFVKD 261
>UniRef50_Q2FMN4 Cluster: Pyruvate kinase; n=1; Methanospirillum
hungatei JF-1|Rep: Pyruvate kinase - Methanospirillum
hungatei (strain JF-1 / DSM 864)
Length = 500
Score = 82.6 bits (195), Expect = 1e-14
Identities = 59/207 (28%), Positives = 102/207 (49%)
Frame = +2
Query: 146 SSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSY 325
S +R + II TIGPAS N ++ +M+ +GM++AR+N SHGS +H ET++ R
Sbjct: 29 SCTMRRTKIIATIGPASSNPRIIREMILSGMDIARLNLSHGSPPWHEETVQQIRALADEL 88
Query: 326 SAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIY 505
+ ++G I +D GP++R L+ S ++ G+TI + ++ + I+
Sbjct: 89 NREIG------ILVDIPGPKLRV-LIH---SPPRDVVPGDTIHIAAEHEHA----SGAIH 134
Query: 506 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDL 685
V + V PG+ + + DG +++ LT T+ +GG + GV +PG D+
Sbjct: 135 VHPPDCIPKVCPGDVVLVGDGAVTLQVLKPGPPMLT-TVISGGTIREGMGVVIPGRRPDV 193
Query: 686 PAVSEKDKSDLLFGVEQGVDMIFASFI 766
P + + G D I SF+
Sbjct: 194 PYAGARFIDYIRQGAALRPDYIALSFV 220
>UniRef50_Q4YDL9 Cluster: Putative uncharacterized protein; n=1;
Plasmodium berghei|Rep: Putative uncharacterized protein
- Plasmodium berghei
Length = 158
Score = 81.8 bits (193), Expect = 2e-14
Identities = 47/123 (38%), Positives = 69/123 (56%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
I+CT+GPA ++V L ++++ GM++ R NFSHG+H+ H + N +A+
Sbjct: 41 IVCTLGPACKSVETLVQLIDAGMDICRFNFSHGTHDDH-KMFENVLKAQAQ-----RPNC 94
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
+L + LD KGPEIRTGLL G+ E LK+G +KL +DY G+ I Y T
Sbjct: 95 TLGMLLDNKGPEIRTGLL---GNKEAHLKEGSKLKLV--ADYSYLGDETCIACSYTKCTT 149
Query: 530 VVK 538
K
Sbjct: 150 KCK 152
>UniRef50_A2BLH1 Cluster: Pyruvate kinase; n=1; Hyperthermus
butylicus DSM 5456|Rep: Pyruvate kinase - Hyperthermus
butylicus (strain DSM 5456 / JCM 9403)
Length = 466
Score = 80.6 bits (190), Expect = 4e-14
Identities = 57/200 (28%), Positives = 96/200 (48%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
II +IGP+S + V+ ++ E G++ R+NF+HG E REAE+ K G P
Sbjct: 8 IIASIGPSSGSPEVILRLAELGVSGFRINFAHGEPSLWREWAEYVREAER----KTGRP- 62
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
LA+ D GP IR G ++ ++L G+ + + E G+ I + + +
Sbjct: 63 -LALIGDLVGPSIRLGRVKN----PIKLNAGDRAEFRCVEE-SEGGDTKIIPLPVRRVYE 116
Query: 530 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 709
V+ G+ I +DDG + + VS + + SRK + + G LP +S++D
Sbjct: 117 VLDEGDLIVMDDGRVRLRVLEVSGYSAIVEALTPATITSRKAIAIRGKDPGLPTLSQRDV 176
Query: 710 SDLLFGVEQGVDMIFASFIR 769
+ F ++ G D I S +R
Sbjct: 177 EHVKFALDNGFDYIALSHVR 196
>UniRef50_UPI000155B976 Cluster: PREDICTED: similar to pyruvate
kinase, liver and RBC, partial; n=1; Ornithorhynchus
anatinus|Rep: PREDICTED: similar to pyruvate kinase,
liver and RBC, partial - Ornithorhynchus anatinus
Length = 339
Score = 79.0 bits (186), Expect = 1e-13
Identities = 35/57 (61%), Positives = 45/57 (78%)
Frame = +2
Query: 608 LTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGA 778
L +E+GG LGSRKGVN+PG +DLPAVSE+D DL FG++Q VD++FASF+R A
Sbjct: 55 LVTEVESGGRLGSRKGVNVPGAVLDLPAVSEQDARDLRFGLDQDVDIVFASFVRKAA 111
>UniRef50_A7QTW5 Cluster: Chromosome undetermined scaffold_171,
whole genome shotgun sequence; n=1; Vitis vinifera|Rep:
Chromosome undetermined scaffold_171, whole genome
shotgun sequence - Vitis vinifera (Grape)
Length = 622
Score = 77.4 bits (182), Expect = 4e-13
Identities = 62/216 (28%), Positives = 106/216 (49%), Gaps = 11/216 (5%)
Frame = +2
Query: 158 RLSGIICTIGP-ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
R + I+ T+G + N ++ ++++G + R+N +HG+ +E IR R + S
Sbjct: 258 RTAHIMVTVGQEVTENETLITDILKSGATIIRINCAHGNPSIWSEIIRRVRRS----SQM 313
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQE----KGNADTI 502
L P I +D GP++RTG ++ G V L+ G+ + ++ S ++ + D
Sbjct: 314 LEKP--CRILMDLAGPKLRTGNMKAG-PCFVRLRVGDLLIISLDSSIEQDELTQPTVDAY 370
Query: 503 YVDYKN--ITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIEN----GGMLGSRKGVNL 664
V + + + VKPG I DDG I + Q SA + +I + G LG+ K +N+
Sbjct: 371 RVTCPSSFLFDSVKPGEPIAFDDGKIWGVIQGTSASEIIVSITHASPRGTKLGAEKSINI 430
Query: 665 PGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRN 772
P + ++ KD DL F V DM+ SFIR+
Sbjct: 431 PESNIRFEGLTTKDLMDLEF-VAAHADMVGISFIRD 465
>UniRef50_A5JEK8 Cluster: Pyruvate kinase; n=1; Nosema bombycis|Rep:
Pyruvate kinase - Nosema bombycis
Length = 441
Score = 77.4 bits (182), Expect = 4e-13
Identities = 56/204 (27%), Positives = 103/204 (50%)
Frame = +2
Query: 161 LSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLG 340
++ II T+ S + L ++ G+++ R+N SHG+ H +I N R+ K ++G
Sbjct: 5 MTKIIVTVSSVSDDEETLTNFLKEGVHIFRINLSHGTSYQHEHSILNIRKCAK----EMG 60
Query: 341 SPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKN 520
I LDT+GPE+R + E +E+ LK+G+ I T S+ + ++ I++ +
Sbjct: 61 --IVPVICLDTRGPEVRIEIAE---RSEIPLKEGDKI---TFSNVR---TSNKIFLPIPD 109
Query: 521 ITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 700
T ++I++DD +++I S T N L + K +LPG+ +
Sbjct: 110 FTKFPLK-SKIYLDDAMLAIEVLETSKCECTGRAMNSHRLKNNKKASLPGLVFEDNESEA 168
Query: 701 KDKSDLLFGVEQGVDMIFASFIRN 772
+DK D ++ +D++FASFI +
Sbjct: 169 RDKKDFEIILKHKIDVVFASFINS 192
>UniRef50_A1RX09 Cluster: Pyruvate kinase; n=1; Thermofilum pendens
Hrk 5|Rep: Pyruvate kinase - Thermofilum pendens (strain
Hrk 5)
Length = 464
Score = 76.6 bits (180), Expect = 7e-13
Identities = 52/203 (25%), Positives = 93/203 (45%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
++ T+GP+S + +++M+ G+N R+NFSH + E + R E
Sbjct: 6 LVATLGPSSWSEETMKRMVAEGVNAFRLNFSHVDYARFEELAKQVRRLETPLRP------ 59
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
L + D +GP IR G A +++ G+ + T SS +EK + V
Sbjct: 60 -LTLIADLQGPVIRLGEF-----APFQVRPGDRVTFTLSSKTEEKY---AVPVPNGVFFE 110
Query: 530 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 709
+V+ G+ + ++ G ++ + G + RK V + G + LP ++EKD
Sbjct: 111 IVREGDEVLVEGGRLAFRIVDAGPEKAVGEALLEGEVKPRKTVTVRGKDIPLPTITEKDL 170
Query: 710 SDLLFGVEQGVDMIFASFIRNGA 778
D+ F V+ G D I SF+R+ +
Sbjct: 171 RDIEFSVKAGFDAIALSFVRSSS 193
>UniRef50_Q97ZD7 Cluster: Pyruvate kinase; n=4; Sulfolobaceae|Rep:
Pyruvate kinase - Sulfolobus solfataricus
Length = 452
Score = 70.5 bits (165), Expect = 4e-11
Identities = 61/204 (29%), Positives = 104/204 (50%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
+R + I+ T+GP+S K + ++V R+NF+HG H R + ++Y+
Sbjct: 1 MRKTKIVATLGPSSEEKV---KELAEYVDVFRINFAHGDETSH----RKYFDLIRTYA-- 51
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
P S +I +D GP++R G L+ +E+KKG+ I + +K D I VD
Sbjct: 52 ---PES-SIIVDLPGPKLRLGELK----EPIEVKKGDKIV------FSQK---DGIPVDD 94
Query: 515 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 694
+ + VK + I I DG I + +S + D + T+ GG+L SRKG+N+P + + +
Sbjct: 95 ELFYSAVKENSDILIADGTIRVRVKSKAKDRVEGTVIEGGILLSRKGINIPNVNLK-SGI 153
Query: 695 SEKDKSDLLFGVEQGVDMIFASFI 766
++ D L ++ G D I SF+
Sbjct: 154 TDNDLKLLKRALDLGADYIGLSFV 177
>UniRef50_UPI00006CE5D4 Cluster: pyruvate kinase family protein;
n=1; Tetrahymena thermophila SB210|Rep: pyruvate kinase
family protein - Tetrahymena thermophila SB210
Length = 495
Score = 66.1 bits (154), Expect = 9e-10
Identities = 60/225 (26%), Positives = 100/225 (44%), Gaps = 19/225 (8%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 337
R + I+CT+GP S +V ++ K++++GMNVAR+ + HG K
Sbjct: 22 RKTKIVCTLGPQSSSVEMICKLLDSGMNVARITYCHG--------------------LKQ 61
Query: 338 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 517
G ++ D K EI+ G ++ + K+ +Y+ G+ I
Sbjct: 62 GPDIRTSLLKDKKPIEIKK-----GQKLKITFNRFLIQKVDEQPEYE--GDEQGIGCSIA 114
Query: 518 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 697
++ +V+ G + + D I V+ + EN G+L K V LPG+ +DLP +S
Sbjct: 115 -LSKLVQVGQHVLLSDNTIYSHVVEVNESDIVVQFENEGILNEVKNVRLPGVKIDLPTIS 173
Query: 698 EKD------KSDLLF-------------GVEQGVDMIFASFIRNG 775
E+ K+D F G+E+GVD I SF+R+G
Sbjct: 174 EEGIFIIQFKNDQQFQLILIDEDFIISQGLEKGVDFIAVSFVRSG 218
>UniRef50_Q9PQV7 Cluster: Pyruvate kinase; n=1; Ureaplasma
parvum|Rep: Pyruvate kinase - Ureaplasma parvum
(Ureaplasma urealyticum biotype 1)
Length = 474
Score = 66.1 bits (154), Expect = 9e-10
Identities = 53/192 (27%), Positives = 86/192 (44%), Gaps = 5/192 (2%)
Frame = +2
Query: 212 LEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIR 391
++ ++ +G+N+ RMN SHG + H + ++ K+ I DTKGPEIR
Sbjct: 41 IKDLILSGVNIFRMNLSHGDQKIHLFRTQLIKKIADELKIKV------EILFDTKGPEIR 94
Query: 392 TGLLEGGGSAEVELKKGETI---KLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFID 562
+ +K E I K + E D N+ + VK +RI ID
Sbjct: 95 VCEMSDNNFI---IKNSEVIIHCKEKVLGSFNEFSVTDA--TGQYNMISDVKINHRILID 149
Query: 563 DGLISIICQSVS--ADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQ 736
DG + +I + + + + T +N L + K +NLP LP +S+KD D+ V+
Sbjct: 150 DGKLILIVKKIDFLKNIIYTTAKNSYSLKTNKRLNLPDANYSLPFLSKKDIDDINLAVKL 209
Query: 737 GVDMIFASFIRN 772
+ + SFI N
Sbjct: 210 KIPYLALSFISN 221
>UniRef50_Q7NJ33 Cluster: Pyruvate kinase; n=1; Gloeobacter
violaceus|Rep: Pyruvate kinase - Gloeobacter violaceus
Length = 501
Score = 65.7 bits (153), Expect = 1e-09
Identities = 57/210 (27%), Positives = 94/210 (44%), Gaps = 8/210 (3%)
Frame = +2
Query: 158 RLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
R + I+ T+ A + +L ++ GMN AR+N H S + N R AE+
Sbjct: 142 RATRIMVTLPSEAEGDYRLLCALIRAGMNCARINCVHDSETVWERMVGNIRRAEREVGR- 200
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADT---IY 505
+ I +D GP++RTG L + + L+KGE + L ++ D+ +
Sbjct: 201 -----ACRILMDLGGPKLRTGPL----AEPLTLRKGEGLVLCRDAEEGRSACEDSPARVV 251
Query: 506 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTI----ENGGMLGSRKGVNLPGI 673
I V+ G + DDG I + + V+ D + I + G L + KG+N P
Sbjct: 252 CAVSGIYGGVQVGEAVLFDDGKIESVVRGVAQDEIQLEITRADDKGSRLAADKGINFPES 311
Query: 674 PVDLPAVSEKDKSDLLFGVEQGVDMIFASF 763
+ L +SE+D L F V + D++ SF
Sbjct: 312 RLKLRGLSEQDLEHLDF-VARRADIVGMSF 340
>UniRef50_A6LTB0 Cluster: Pyruvate kinase; n=1; Clostridium
beijerinckii NCIMB 8052|Rep: Pyruvate kinase -
Clostridium beijerinckii NCIMB 8052
Length = 340
Score = 65.7 bits (153), Expect = 1e-09
Identities = 58/205 (28%), Positives = 95/205 (46%), Gaps = 6/205 (2%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
II T+GP ++ AVL+ ++E+G+N R NF HGS E E ++ ++ +
Sbjct: 3 IIGTVGPNVKDRAVLKGIIESGVNALRFNFIHGSAEEFLEFLKMAKDIKS---------- 52
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQE--KGNADTIYVDYKNI 523
+ + LD G ++R + G ++ GE I Y E K + + I V NI
Sbjct: 53 DIQVMLDLSGTKVR---VSGKFQYIFKVYNGEVIYFCGEDKYSEVVKNSKNKIKVIPLNI 109
Query: 524 TNVV---KPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPA 691
N + K +I I D ++ I V TI GG++ KG N+ +
Sbjct: 110 KNKILNEKDYKQIGIKDNTMTFDIVDKVDGLIKAITI-RGGVIRKWKGCNIKNLERKELP 168
Query: 692 VSEKDKSDLLFGVEQGVDMIFASFI 766
++E DK +++GV VD+I SF+
Sbjct: 169 LNENDKDAIVWGVNNKVDIICQSFV 193
>UniRef50_Q8MR79 Cluster: Pyruvate kinase; n=3; Sophophora|Rep:
Pyruvate kinase - Drosophila melanogaster (Fruit fly)
Length = 659
Score = 64.1 bits (149), Expect = 4e-09
Identities = 50/182 (27%), Positives = 84/182 (46%), Gaps = 4/182 (2%)
Frame = +2
Query: 233 GMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTG----L 400
G+ +N G+ + I REAE S S +LG P + ++ + TG
Sbjct: 175 GVRCFMVNLFEGTQHDNQSLIVKLREAEISVSKELGFPVTSSVMVKISPRHQFTGGFSTQ 234
Query: 401 LEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISI 580
G VEL +G+ + LT Y ++ NAD IYV+ + + V P + I I + I +
Sbjct: 235 FRQEGKKCVELVQGQKVILTVDRQYSDRSNADVIYVNARFLIVDVHPLDFILIGED-IQL 293
Query: 581 ICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFAS 760
+ +S+ AD L + GGML + V P +S ++ DL F E G++++ +
Sbjct: 294 MVRSIHADHLKGCVARGGMLYAHMPVLFPA-RCRRFRISYEELEDLTFAREVGLNVVVSH 352
Query: 761 FI 766
+
Sbjct: 353 IV 354
>UniRef50_P19680 Cluster: Pyruvate kinase; n=1; Spiroplasma
citri|Rep: Pyruvate kinase - Spiroplasma citri
Length = 192
Score = 64.1 bits (149), Expect = 4e-09
Identities = 34/73 (46%), Positives = 44/73 (60%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
II TIGP++ + +E++ +TGM R+NFSHG H I RE SAK+G P
Sbjct: 15 IITTIGPSTHSPGAIEELFKTGMTTIRLNFSHGDHAEQGARIVWAREV----SAKIGKPI 70
Query: 350 SLAIALDTKGPEI 388
S + LDTKGPEI
Sbjct: 71 S--VLLDTKGPEI 81
>UniRef50_Q2JJ60 Cluster: Pyruvate kinase; n=5; Bacteria|Rep:
Pyruvate kinase - Synechococcus sp. (strain
JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone
B-Prime)
Length = 476
Score = 63.3 bits (147), Expect = 7e-09
Identities = 53/214 (24%), Positives = 99/214 (46%), Gaps = 5/214 (2%)
Frame = +2
Query: 158 RLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
R + I+ T+ A+ +L +++E GMNVAR+N +H + + + R+AE +
Sbjct: 118 RRARIMVTLPSEAAEQPELLLQLLERGMNVARINCAHDEPSVWEKMVAHLRQAEAQTQRR 177
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
I LD GP+IRTG + + ++ +G+ I LT + +
Sbjct: 178 ------CKILLDLAGPKIRTGPV-AMPPGKTKVYRGDRILLTAKVPEASADISCQVTCSL 230
Query: 515 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIE----NGGMLGSRKGVNLPGIPVD 682
+ ++ G ++IDDG I + + ++ G L + KG+N P +
Sbjct: 231 PEVLAHLQVGATVWIDDGKIGARVVRIEPAGVVLEVDKVAPQGKKLRAEKGLNFPDSQLQ 290
Query: 683 LPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAAL 784
+ ++++KD DL F V + D++ SF++ A L
Sbjct: 291 IRSLTDKDCQDLDF-VVRHADLVGYSFVQQPADL 323
>UniRef50_Q57572 Cluster: Pyruvate kinase; n=6; Methanococcales|Rep:
Pyruvate kinase - Methanococcus jannaschii
Length = 447
Score = 59.7 bits (138), Expect = 8e-08
Identities = 61/206 (29%), Positives = 95/206 (46%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
+R + I+ T+GP+ N L+K + ++ R N SH + +Y E N EK+ AK
Sbjct: 5 MRKTKILVTLGPSLENK--LDKAINL-IDGVRFNMSHATTDY-CEKFLNI--LEKNNIAK 58
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
+ +D KG +IR ++ LK GE K+ D + N DTI
Sbjct: 59 V---------MDLKGIKIRIKEVKLKNKI---LKMGE--KVVIGEDIKLNYNIDTI---- 100
Query: 515 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 694
+ G+ I I+DG I + D + +E GG + GVNLP ++LP +
Sbjct: 101 -------EEGHFILINDGKIKLRVVE-KTDKIIAVVEVGGEIKEGMGVNLPDTRIELPII 152
Query: 695 SEKDKSDLLFGVEQGVDMIFASFIRN 772
E D ++ F VE+ + I SF+RN
Sbjct: 153 DETDLKNIKFAVEKDFEYIALSFVRN 178
>UniRef50_A0NLM6 Cluster: Pyruvate kinase; n=2;
Alphaproteobacteria|Rep: Pyruvate kinase - Stappia
aggregata IAM 12614
Length = 512
Score = 58.0 bits (134), Expect = 3e-07
Identities = 52/197 (26%), Positives = 90/197 (45%), Gaps = 5/197 (2%)
Frame = +2
Query: 191 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 370
A+ + A + ++ GMNVAR+N +H E + + R A A+L + I +D
Sbjct: 165 AADDPAFVRDLVRKGMNVARLNCAHDGPEAWEKMAAHVRTA-----AELEGR-DVRILMD 218
Query: 371 TKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGN-ADTIYVDYKNITNVVKPGN 547
GP+IRT + +L GE +L + A T V + N ++ G+
Sbjct: 219 IAGPKIRTETVVPQKKTP-KLTIGERFRLVVQETPDAHSDIAVTASVSLPQMVNRLREGD 277
Query: 548 RIFIDDGLISIICQSVSADTLTCTI----ENGGMLGSRKGVNLPGIPVDLPAVSEKDKSD 715
R+ DD + + + VS + ++G + +KG+NLP + + ++ KDK+D
Sbjct: 278 RLLYDDSKLEGVVEEVSNGEAVIRVTRAKDSGVKIKPQKGINLPDTALGVSPLTAKDKTD 337
Query: 716 LLFGVEQGVDMIFASFI 766
L V DM+ SF+
Sbjct: 338 LK-TVTALADMVGYSFV 353
>UniRef50_A6PUS2 Cluster: Pyruvate kinase; n=1; Victivallis vadensis
ATCC BAA-548|Rep: Pyruvate kinase - Victivallis vadensis
ATCC BAA-548
Length = 357
Score = 57.2 bits (132), Expect = 4e-07
Identities = 26/77 (33%), Positives = 43/77 (55%)
Frame = +2
Query: 542 GNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLL 721
G RI DDG + ++ S L C + G L + K VN+PG + +PA++ KD+ +
Sbjct: 2 GARIIFDDGAMELLVLGKSGGLLHCEAKRDGELKNHKSVNVPGAELKMPALTRKDRDFIE 61
Query: 722 FGVEQGVDMIFASFIRN 772
+ V+ +D I SF+R+
Sbjct: 62 YAVKNDLDFIAHSFVRS 78
>UniRef50_Q3J5D7 Cluster: Pyruvate kinase; n=2; Rhodobacter
sphaeroides|Rep: Pyruvate kinase - Rhodobacter
sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 /
DSM158)
Length = 508
Score = 56.4 bits (130), Expect = 8e-07
Identities = 49/197 (24%), Positives = 94/197 (47%), Gaps = 4/197 (2%)
Frame = +2
Query: 191 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 370
A+ + A++ +++ G + R+N +H E A I + R++E+ KL I++D
Sbjct: 161 AASDPAIVRELVAAGADAFRINCAHDGPEAWAAMIGHIRKSERMTGRKL------PISMD 214
Query: 371 TKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNR 550
GP+ R + + GG L+ G+ +G + + + + + PG +
Sbjct: 215 LGGPKFR--VTKTGGPLPKRLQAGDRFAFVEKPSLAPEGRGWAM-LGHPALLAALAPGVQ 271
Query: 551 IFIDDG-LISIICQSVSADTLTCTI---ENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDL 718
+ +DDG L + + Q+ L E G L +GVNLPG +D+ A++E+D + L
Sbjct: 272 VSVDDGKLWATVIQTGRGHALLEVDRVGERGLKLKPGRGVNLPGSHLDVAALTEEDLAAL 331
Query: 719 LFGVEQGVDMIFASFIR 769
V + D++ SF++
Sbjct: 332 DVVVAE-ADLVAFSFVQ 347
>UniRef50_Q59ZE3 Cluster: Putative uncharacterized protein; n=1;
Candida albicans|Rep: Putative uncharacterized protein -
Candida albicans (Yeast)
Length = 105
Score = 55.2 bits (127), Expect = 2e-06
Identities = 34/93 (36%), Positives = 52/93 (55%), Gaps = 1/93 (1%)
Frame = -1
Query: 789 SCSAAPLRMNDAKIISTPCSTPKSRSDLSFSETAGRSTGMPGRLTPFRDPSIPPFSMVHV 610
S ++ + + +AKI+ T TP S +SFS+ AG+ST +PG+LTP + +P
Sbjct: 13 SKTSLAVSIKEAKIMWTLFLTPNLISAISFSDKAGKSTSVPGKLTPLWEEILPALRDSTF 72
Query: 609 RV-SALTD*QMIEMRPSSMKIRFPGFTTFVMFL 514
+V S+ T+ + PSS + PG T VMFL
Sbjct: 73 KVCSSSTEMTSNDKTPSSTYMILPGAMTLVMFL 105
>UniRef50_P46614 Cluster: Pyruvate kinase; n=1; Candida
albicans|Rep: Pyruvate kinase - Candida albicans (Yeast)
Length = 92
Score = 54.0 bits (124), Expect = 4e-06
Identities = 28/69 (40%), Positives = 38/69 (55%), Gaps = 1/69 (1%)
Frame = +2
Query: 458 TTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSV-SADTLTCTIENGG 634
TT Y+ K + + +DYKNIT V+ PG I++DDG++S SV TL N G
Sbjct: 12 TTDDAYKTKCDDKVMIIDYKNITKVIAPGKIIYVDDGVLSFEVISVDDQQTLKVRSLNAG 71
Query: 635 MLGSRKGVN 661
M+ S K N
Sbjct: 72 MISSHKTAN 80
>UniRef50_Q8XLL6 Cluster: Pyruvate kinase; n=3; Clostridium
perfringens|Rep: Pyruvate kinase - Clostridium
perfringens
Length = 364
Score = 52.8 bits (121), Expect = 9e-06
Identities = 48/188 (25%), Positives = 82/188 (43%), Gaps = 4/188 (2%)
Frame = +2
Query: 212 LEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIR 391
++ +++ G N+ RMN SHG H R+ E + ++ I LD +G +IR
Sbjct: 30 IDNIVKGGGNIIRMNLSHGKH----------RDVECCIDYIRSNHKNVKILLDLQGNKIR 79
Query: 392 TGLLEGGGSAEVELKKGETIKLTTSSDYQEK-GNADTIYVDYKNITNVVKPGN---RIFI 559
G ++ G+ + + Y N D + NI N N +I++
Sbjct: 80 VANNIYG---TFKVNSGDLVYFCSEETYDAYLKNIDRNKLIPLNIKNKFIYNNTFKKIYM 136
Query: 560 DDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQG 739
D + I S + + ++ GG++ KG NLP + VSEKD D+ F ++
Sbjct: 137 KDATMEFIVISNNNGLIKTKVKLGGVVRKEKGCNLPNLDRKNWGVSEKDLEDIKFAIDNK 196
Query: 740 VDMIFASF 763
VD+I S+
Sbjct: 197 VDIIDYSY 204
>UniRef50_Q5M6U9 Cluster: Pyruvate kinase; n=2; Campylobacter
jejuni|Rep: Pyruvate kinase - Campylobacter jejuni
Length = 319
Score = 51.2 bits (117), Expect = 3e-05
Identities = 48/203 (23%), Positives = 91/203 (44%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
+I T GP+ L ++ + + R+N +HG E TI N R+ +
Sbjct: 4 LILTTGPSLGGKINLNQIHQDKF-IYRINGAHGDIESIKNTIINLRKQKAD--------- 53
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
+ I +D G +IRT G S ++++K + L +YK
Sbjct: 54 -IDILIDLPGNKIRTS----GISEAIQVEKDKDFSLKIDQ------------FNYKEFYK 96
Query: 530 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 709
+VKPG ++ +D + I + V+ + T ++ G+L + KG+++ + ++P + EKDK
Sbjct: 97 LVKPGMEVYANDSVFLFIVKEVNDKEIIFTSKSTGLLLNNKGMHVRNLHDNIPFLFEKDK 156
Query: 710 SDLLFGVEQGVDMIFASFIRNGA 778
+ E + + ASF+R +
Sbjct: 157 ELIKLCNEFDIAYVGASFVRKAS 179
>UniRef50_Q8FLV7 Cluster: Pyruvate kinase; n=6; Corynebacterium|Rep:
Pyruvate kinase - Corynebacterium efficiens
Length = 630
Score = 47.2 bits (107), Expect = 5e-04
Identities = 37/131 (28%), Positives = 58/131 (44%), Gaps = 12/131 (9%)
Frame = +2
Query: 416 SAEVELKKGETIKLTTSSDYQEK----GNADTIYVDYKNITNVVKPGNRIFIDDGLISII 583
S + LK G + LT+ + G I +K G+R+ DDG I+ +
Sbjct: 331 SQRINLKVGNRLFLTSEEVVYDPSAGHGRIPKISCTLPEAVGAIKVGHRVLFDDGSIAAV 390
Query: 584 C--------QSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQG 739
C V +T G L + KG+NLP + LP+++E+D L F V +
Sbjct: 391 CIDRREHDGHHVVELEVTRARPQGVNLAAYKGINLPDSELPLPSLTEEDLRHLRF-VAKH 449
Query: 740 VDMIFASFIRN 772
D++ SFIR+
Sbjct: 450 ADIVNVSFIRD 460
>UniRef50_A3PTF7 Cluster: Pyruvate kinase; n=5; Mycobacterium|Rep:
Pyruvate kinase - Mycobacterium sp. (strain JLS)
Length = 615
Score = 47.2 bits (107), Expect = 5e-04
Identities = 32/101 (31%), Positives = 49/101 (48%), Gaps = 4/101 (3%)
Frame = +2
Query: 479 EKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIEN----GGMLGS 646
+ G A I + + +PG +I DDG I +V D L I+ G LGS
Sbjct: 354 DHGGAPRIGCTLPEVFDHARPGEKIRFDDGRIGGEIVAVERDALRVRIDRTAPGGSKLGS 413
Query: 647 RKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIR 769
KGVN+P + + A+++KD DL V D++ SF++
Sbjct: 414 AKGVNVPDTHLPIAALTDKDVEDLA-TVVAIADIVQISFVQ 453
Score = 44.8 bits (101), Expect = 0.002
Identities = 31/108 (28%), Positives = 53/108 (49%), Gaps = 1/108 (0%)
Frame = +2
Query: 92 ANVGSQLQHMCGLDIDSKSSYIRLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHG 268
ANVG +L +D+ + R + I+ T+ A+ + ++ ++ GMNVAR+N +H
Sbjct: 116 ANVGDELLREHAVDLFGPAPAERATRIMVTLPSSAATDPDLVRDLIARGMNVARINCAHD 175
Query: 269 SHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGG 412
E + R A +S K +A+D GP++RTG + G
Sbjct: 176 DAEAWTAMAGHVRRAAESTGRK------CLVAMDLAGPKLRTGPIRPG 217
>UniRef50_Q9V2V8 Cluster: Pyruvate kinase; n=1; Thermoproteus
tenax|Rep: Pyruvate kinase - Thermoproteus tenax
Length = 446
Score = 47.2 bits (107), Expect = 5e-04
Identities = 47/205 (22%), Positives = 90/205 (43%), Gaps = 2/205 (0%)
Frame = +2
Query: 170 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 349
I+ T+GP++ + + ++ V R+N SH S + R+ E++ S
Sbjct: 5 IVATLGPSTDRLPDITALLSKVHGV-RINMSHASPSEVEARVNAVRKYEET------SGR 57
Query: 350 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 529
+AI D +GP +RTGL+ +++ G + S EKG+ + V +
Sbjct: 58 YIAIIADLRGPSVRTGLMR-----PLQITAGARV----SFKLAEKGDG-FVPVPRREFFE 107
Query: 530 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 709
V++ G+ + + DG + + S + + + G++ S K + + G + E+D
Sbjct: 108 VIEEGDEVLMLDGKLVLRIISAAQTSAEAESLSSGVISSNKAIVVKGKEYHIEQPVEEDI 167
Query: 710 SDL--LFGVEQGVDMIFASFIRNGA 778
L L VD + S +R+GA
Sbjct: 168 RALQTLSRFRDDVDYVALSLVRDGA 192
>UniRef50_Q8DLH6 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep:
Pyruvate kinase - Synechococcus elongatus
(Thermosynechococcus elongatus)
Length = 506
Score = 46.8 bits (106), Expect = 6e-04
Identities = 49/187 (26%), Positives = 78/187 (41%), Gaps = 3/187 (1%)
Frame = +2
Query: 221 MMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGL 400
++ GMN AR+N +H I + R A S G P I +D GP+ R
Sbjct: 160 LLRKGMNCARVNCAHDDPATWEAMIEHLRAA----SHITGQP--CKILMDLGGPKPRIAD 213
Query: 401 LEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLIS- 577
+ V + G+ ++LTT E G I ++ G R++IDDG
Sbjct: 214 I---FPETVRVHSGDRLRLTTEI-CPEGGEIPQFTCSLPEIVPQLEVGQRVWIDDGRTGG 269
Query: 578 -IICQSVSADTLTCT-IENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMI 751
I+ + LT T + G L KG+N P + L ++ D+ L F D+I
Sbjct: 270 RIVSKDAQGVELTITHCKEGQRLKVAKGLNFPDSDLRLCPLTASDREHLAFACRY-ADII 328
Query: 752 FASFIRN 772
S++++
Sbjct: 329 GYSYVQS 335
>UniRef50_Q22CT0 Cluster: Pyruvate kinase, barrel domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep:
Pyruvate kinase, barrel domain containing protein -
Tetrahymena thermophila SB210
Length = 747
Score = 46.8 bits (106), Expect = 6e-04
Identities = 43/147 (29%), Positives = 74/147 (50%), Gaps = 1/147 (0%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREA-EKSYSAK 334
R + I+ TI + L+ M+E G+N +N ++ + + T+R R+A EK + +
Sbjct: 66 RRTKIVGTISSFYSSYENLKSMVEAGLNSFMVNMAYCTPDLLV-TLRKHRDALEKEFDIQ 124
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
L P + + KG +R G L E+ L+KG+ ++ + ++ GN+ VD
Sbjct: 125 L--PITCVL----KGTLVRIGTLM---QPEIFLRKGQEYRIVLN--HKVLGNSLYCAVDD 173
Query: 515 KNITNVVKPGNRIFIDDGLISIICQSV 595
K I VK GN+I ID G IS+ + +
Sbjct: 174 KEIIRRVKVGNQILIDYGQISMTIKRI 200
>UniRef50_Q9M3B6 Cluster: Pyruvate kinase; n=1; Arabidopsis
thaliana|Rep: Pyruvate kinase - Arabidopsis thaliana
(Mouse-ear cress)
Length = 710
Score = 46.4 bits (105), Expect = 8e-04
Identities = 36/124 (29%), Positives = 55/124 (44%), Gaps = 8/124 (6%)
Frame = +2
Query: 425 VELKKGETIKLTTSSDYQEKG----NADTIYVDYKNITNVVKPGNRIFIDDGLISIICQS 592
V LK G+ + +T E A + + + VKPG I DDG I + +
Sbjct: 437 VRLKVGDLLVITREGSLDEPSVTVPGAHRLTCPSGYLFDSVKPGETIGFDDGKIWGVIKG 496
Query: 593 VSADTLTCTIEN----GGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFAS 760
S + +I + G LGS K +N+P + ++ KD DL + V DM+ S
Sbjct: 497 TSPSEVIVSITHARPKGTKLGSEKSINIPQSDIHFKGLTSKDIKDLDY-VASHADMVGIS 555
Query: 761 FIRN 772
FIR+
Sbjct: 556 FIRD 559
Score = 37.1 bits (82), Expect = 0.50
Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
Frame = +2
Query: 158 RLSGIICTIGP-ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
R + I+ TIG A+ + + +++ G +V R+N +HG E I+ R S
Sbjct: 234 RSTHIMVTIGEEATLSETFITDILKAGTSVIRINCAHGDPSIWGEIIKRVRRT----SQM 289
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGG 412
L P + +D GP++RTG L+ G
Sbjct: 290 LEMP--CRVHMDLAGPKLRTGTLKPG 313
>UniRef50_A4ARB8 Cluster: Pyruvate kinase; n=1; Flavobacteriales
bacterium HTCC2170|Rep: Pyruvate kinase -
Flavobacteriales bacterium HTCC2170
Length = 624
Score = 45.2 bits (102), Expect = 0.002
Identities = 25/83 (30%), Positives = 44/83 (53%), Gaps = 4/83 (4%)
Frame = +2
Query: 536 KPGNRIFIDDGLISIICQSVSADTLTCTI----ENGGMLGSRKGVNLPGIPVDLPAVSEK 703
K G I+ DDG I I + V+A+ + I + G L + KG+NLP + + ++ K
Sbjct: 377 KKGEPIYFDDGKIEGIIEKVTAEDIVVKITHAKDKGSKLKADKGINLPKSDLKISGLTNK 436
Query: 704 DKSDLLFGVEQGVDMIFASFIRN 772
D+ D+ F + + D + SF+ +
Sbjct: 437 DREDIKF-IAKHADAVNFSFVNS 458
Score = 43.6 bits (98), Expect = 0.006
Identities = 28/86 (32%), Positives = 47/86 (54%), Gaps = 2/86 (2%)
Frame = +2
Query: 158 RLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
R + I+ T+ A+ ++ + K++ GMN AR+N +H + E + I N + A K K
Sbjct: 131 RFTRIMVTLPNTAAEDLGFIRKLLANGMNCARINCAHDTPEDWLKMIDNLKIASKRQRKK 190
Query: 335 LGSPFSLAIALDTKGPEIRTG-LLEG 409
IA+D GP++RTG ++EG
Sbjct: 191 ------CKIAMDLSGPKLRTGPMVEG 210
>UniRef50_UPI000049906E Cluster: pyruvate kinase; n=3; Entamoeba
histolytica HM-1:IMSS|Rep: pyruvate kinase - Entamoeba
histolytica HM-1:IMSS
Length = 321
Score = 43.6 bits (98), Expect = 0.006
Identities = 35/138 (25%), Positives = 69/138 (50%), Gaps = 2/138 (1%)
Frame = +2
Query: 359 IALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVK 538
I +D +G +IR + + L K ++++LT + ++ I++ N ++
Sbjct: 54 IYVDLQGSKIRISRSQ----PNLILTKDQSVELTIKAPTKD---TKAIHIGNPNTIKLLS 106
Query: 539 PGNRIFIDDGLISIICQSVS-ADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSD 715
G + IDDG + I+ S+ ++T T+ GG L KG NL P +SE+D ++
Sbjct: 107 QGTHVKIDDGRMEIVVNSIKDSETAIATVIKGGELKPGKGFNLQPHPFVQNQLSERD-AE 165
Query: 716 LLFGVEQGVDMIFA-SFI 766
++ ++ ++ FA SF+
Sbjct: 166 IVEKLKDVKEVCFALSFV 183
>UniRef50_A7QZ91 Cluster: Chromosome undetermined scaffold_267,
whole genome shotgun sequence; n=1; Vitis vinifera|Rep:
Chromosome undetermined scaffold_267, whole genome
shotgun sequence - Vitis vinifera (Grape)
Length = 314
Score = 43.2 bits (97), Expect = 0.008
Identities = 29/110 (26%), Positives = 53/110 (48%), Gaps = 1/110 (0%)
Frame = +2
Query: 314 EKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNA 493
+K++ + F +AI +DT+G EI G L SA+ E GE I + + +
Sbjct: 184 KKAFLTEQEKGFVVAIMMDTEGSEIHMGELGSAPSAKTE--DGE-IWIFSVQTFDSPRPE 240
Query: 494 DTIYVDYKNITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGML 640
TI ++Y VK G+ + +D G++ + + + D + C + G+L
Sbjct: 241 STININYDGFAEDVKVGDELLVDSGMVRFDVIEKIGPD-VKCRCTDPGLL 289
>UniRef50_A6PU80 Cluster: Pyruvate kinase; n=1; Victivallis vadensis
ATCC BAA-548|Rep: Pyruvate kinase - Victivallis vadensis
ATCC BAA-548
Length = 121
Score = 42.7 bits (96), Expect = 0.010
Identities = 39/133 (29%), Positives = 61/133 (45%)
Frame = +2
Query: 155 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 334
++ + I+ TI ++ +L + + GM+V R+N +H + R+
Sbjct: 1 MKYTKIVATINASTCTEELLRGLYKNGMDVVRLNTAHMEIADMDRIVALVRKVSDK---- 56
Query: 335 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 514
LAI +DTKGP IRT L+ A + LK G+ + LT + QEK + V+Y
Sbjct: 57 ------LAIMVDTKGPNIRTCNLD----APLALKIGDKLDLTGETVPQEK----AVQVNY 102
Query: 515 KNITNVVKPGNRI 553
T V G RI
Sbjct: 103 SKFTAEVPVGARI 115
>UniRef50_A1U5Q4 Cluster: Pyruvate kinase; n=2; Marinobacter
aquaeolei VT8|Rep: Pyruvate kinase - Marinobacter
aquaeolei (strain ATCC 700491 / DSM 11845 /
VT8)(Marinobacter hydrocarbonoclasticus (strain DSM
11845))
Length = 626
Score = 42.7 bits (96), Expect = 0.010
Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 4/96 (4%)
Frame = +2
Query: 497 TIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIEN----GGMLGSRKGVNL 664
TI + + V PG ++ DDG I + + V D I++ G L + KG+NL
Sbjct: 373 TISCTMPEVVSQVHPGESVWFDDGKIGGVIEKVETDRFWVKIQHARPEGSKLRAGKGMNL 432
Query: 665 PGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRN 772
P +++ +++ D S L F + + D + SF+ +
Sbjct: 433 PDSQLNVSSLTPTDISHLTF-IAKHADAVQMSFVNS 467
Score = 41.5 bits (93), Expect = 0.023
Identities = 21/74 (28%), Positives = 41/74 (55%)
Frame = +2
Query: 191 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 370
++++ +++ +++ GMN R+N +H E E I N + A++ + S + +D
Sbjct: 154 SAQDPSIIRDLLKAGMNCMRINCAHDDPETWLEMINNLQTAKEEFGQ------SCQVFMD 207
Query: 371 TKGPEIRTGLLEGG 412
GP+IRTG +E G
Sbjct: 208 LGGPKIRTGEIEPG 221
>UniRef50_Q5KVI2 Cluster: Pyruvate kinase; n=2; Geobacillus|Rep:
Pyruvate kinase - Geobacillus kaustophilus
Length = 660
Score = 41.9 bits (94), Expect = 0.018
Identities = 32/113 (28%), Positives = 55/113 (48%), Gaps = 2/113 (1%)
Frame = +2
Query: 107 QLQHMCGLDIDSKSSYIRLSGIICTIGPA-SRNVAVLEKMMETGMNVARMNFSHGSHEYH 283
QL H + S +R + I+ T+ A ++E+++ GM++AR+N ++GS E
Sbjct: 154 QLLHKRAEAVFGSPSSVRPTRIMVTMDEAWVDEPGLIERLLLYGMDIARINCAYGSPETW 213
Query: 284 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTG-LLEGGGSAEVELKK 439
+ R+AEK +L I +D GP+IR L G ++ +KK
Sbjct: 214 EALVAIIRQAEKQLEQQLQGR-RCRIYMDLPGPKIRVDRLAVNAGPMKLSVKK 265
>UniRef50_Q648E3 Cluster: Pyruvate kinase; n=1; uncultured archaeon
GZfos3D4|Rep: Pyruvate kinase - uncultured archaeon
GZfos3D4
Length = 588
Score = 41.1 bits (92), Expect = 0.031
Identities = 50/195 (25%), Positives = 81/195 (41%), Gaps = 23/195 (11%)
Frame = +2
Query: 236 MNVARMNFS-HGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGG 412
++V RMN + H E + RE +K G ++A+ D GP+IR G G
Sbjct: 2 VDVIRMNMAFHKGGETERAIFKWLRENKK------GMTKNVAVLGDLPGPKIRLG---GV 52
Query: 413 GSAEVELKKGETIKL---TTSSDYQEKGNADTIYVDYKNITNVVKPGNR----------- 550
G A +++ KGE L + + K ++ V+ K VVK N
Sbjct: 53 GGA-IKVSKGEHFDLYFRKRNEVSKSKRAGASVLVNDKPFEEVVKKINEYDGIGDYIGES 111
Query: 551 --------IFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKD 706
I I DG + + S + C +E G + KGV + +D P+ ++D
Sbjct: 112 IRNNKDVVISIADGSVILKAVGESEGVVECEVEKEGEIKDHKGVTIKRAELDAPSFEQRD 171
Query: 707 KSDLLFGVEQGVDMI 751
K L F +++G D +
Sbjct: 172 KEALRFLLDEGGDFL 186
>UniRef50_Q4IUP8 Cluster: Pyruvate kinase; n=1; Azotobacter
vinelandii AvOP|Rep: Pyruvate kinase - Azotobacter
vinelandii AvOP
Length = 165
Score = 40.7 bits (91), Expect = 0.041
Identities = 18/51 (35%), Positives = 29/51 (56%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCRE 310
R + I+ T+G A+ +E +++ G++V R+NFSHG E H RE
Sbjct: 3 RRTKIVATLGSATETPEAIEGLVKAGVDVVRLNFSHGKAEEHQARATLVRE 53
>UniRef50_A4VPY3 Cluster: Pyruvate kinase; n=1; Pseudomonas stutzeri
A1501|Rep: Pyruvate kinase - Pseudomonas stutzeri
(strain A1501)
Length = 625
Score = 39.9 bits (89), Expect = 0.071
Identities = 24/69 (34%), Positives = 39/69 (56%)
Frame = +2
Query: 191 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 370
A+ N ++E +++ GM+ AR+N +H + I + R AEK+ LG +ALD
Sbjct: 150 AAHNRDLIEALIKEGMDCARINCAHDDPDSWRAMIEHVRAAEKA----LGR--ECKVALD 203
Query: 371 TKGPEIRTG 397
GP++RTG
Sbjct: 204 LAGPKLRTG 212
Score = 37.5 bits (83), Expect = 0.38
Identities = 34/123 (27%), Positives = 51/123 (41%), Gaps = 13/123 (10%)
Frame = +2
Query: 431 LKKGETIKLTTSS---DYQEKGNADTIYVD--YKNITNVVKPGNRIFIDDGLISIICQSV 595
L+ G+ + LT D NA+T + ++ V G+ ++ DDG I +
Sbjct: 337 LRVGDLLALTADDQPIDPPSNDNAETARIGCTLPHVLAAVAAGDPVWFDDGKIGARVEKA 396
Query: 596 SADTLTCTI------ENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQG--VDMI 751
SAD L I L S KG+N P + + A +E D L F + V M
Sbjct: 397 SADALILRITQIAHASGRAKLASDKGINFPDNALPVRAPTEDDIETLAFAAKHADIVQMS 456
Query: 752 FAS 760
FA+
Sbjct: 457 FAN 459
>UniRef50_Q9VVH0 Cluster: CG12229-PA; n=2; Sophophora|Rep:
CG12229-PA - Drosophila melanogaster (Fruit fly)
Length = 571
Score = 39.9 bits (89), Expect = 0.071
Identities = 38/165 (23%), Positives = 75/165 (45%), Gaps = 12/165 (7%)
Frame = +2
Query: 209 VLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKS-----------YSAKLGSPFSL 355
V + + ET + R +G++ +H +T+ N + K+ +SA+ +
Sbjct: 78 VAKLVTETTHDELRRMLENGTYTFHVDTVGNKPDELKAILDTMNIAISAHSAERELRLTT 137
Query: 356 AIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYV-DYKNITNV 532
+AL+ G R G L + V L +G + LTT Y+ KG + +YV + +
Sbjct: 138 GLALEINGECCRVGRLRN--NCTVMLARGGVVTLTTDESYRYKGFKEIVYVINLRCYLAS 195
Query: 533 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLP 667
V+ G+ + I + + +++ + LT I + G++ S + LP
Sbjct: 196 VQLGDIVMIGREVRGKVVKTL-REALTVMIIDAGLVASYDFIELP 239
>UniRef50_UPI00006CB055 Cluster: hypothetical protein TTHERM_00239360;
n=1; Tetrahymena thermophila SB210|Rep: hypothetical
protein TTHERM_00239360 - Tetrahymena thermophila SB210
Length = 1220
Score = 37.1 bits (82), Expect = 0.50
Identities = 19/66 (28%), Positives = 34/66 (51%)
Frame = +2
Query: 320 SYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADT 499
S S + + F+ LDT GP + + ++++K E+IK+ + YQ KGN+
Sbjct: 924 SKSQQNSNQFNQGNQLDTLGPFENNAVQNSLENISLKIEKNESIKIQSKDIYQNKGNSQF 983
Query: 500 IYVDYK 517
+ +D K
Sbjct: 984 LNIDQK 989
>UniRef50_A0V3R8 Cluster: S-layer-like region; n=1; Clostridium
cellulolyticum H10|Rep: S-layer-like region -
Clostridium cellulolyticum H10
Length = 1382
Score = 35.5 bits (78), Expect = 1.5
Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 4/100 (4%)
Frame = +2
Query: 359 IALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIY-VDYKNI--TN 529
I ++ ++R +L+G E+E+ KGE I +T S E D I V NI T
Sbjct: 243 IKIEKNNNKLRIVILDGNTVKEIEIAKGEEIIVTGSVGTLEIATPDVIVKVIAANISDTK 302
Query: 530 VVKPGNRIFID-DGLISIICQSVSADTLTCTIENGGMLGS 646
VV IF+D + I + + SA+ E G ++ +
Sbjct: 303 VVSANASIFVDKESKIKSVSINNSAENTAIKAEKGAVVNT 342
>UniRef50_A7EYT0 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 375
Score = 35.1 bits (77), Expect = 2.0
Identities = 22/59 (37%), Positives = 27/59 (45%), Gaps = 2/59 (3%)
Frame = -1
Query: 774 PLRMNDAKIISTPCSTPKSRSDLSFSETA--GRSTGMPGRLTPFRDPSIPPFSMVHVRV 604
P N STP STP S S S+T RS MPG LTP + P + +R+
Sbjct: 285 PPDQNQDSSTSTPTSTPSSSDSDSNSQTPIFARSPPMPGLLTPSEILTKAPLDKIKIRI 343
>UniRef50_A2STG1 Cluster: Putative anti-sigma regulatory factor,
serine/threonine protein kinase; n=1; Methanocorpusculum
labreanum Z|Rep: Putative anti-sigma regulatory factor,
serine/threonine protein kinase - Methanocorpusculum
labreanum (strain ATCC 43576 / DSM 4855 / Z)
Length = 777
Score = 35.1 bits (77), Expect = 2.0
Identities = 17/48 (35%), Positives = 25/48 (52%)
Frame = +2
Query: 125 GLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHG 268
G ID K +YI+ SG+IC G A + V +KM G + ++ G
Sbjct: 349 GTGIDVKGTYIQNSGMICGTGMAGDGICVAKKMTVYGGKIEATGYTTG 396
>UniRef50_Q9RHY8 Cluster: ORF1 protein; n=1; Corynebacterium
ammoniagenes|Rep: ORF1 protein - Corynebacterium
ammoniagenes (Brevibacterium ammoniagenes)
Length = 320
Score = 34.7 bits (76), Expect = 2.7
Identities = 26/103 (25%), Positives = 44/103 (42%), Gaps = 2/103 (1%)
Frame = -3
Query: 667 GQVDAFPGSEHTSVFNGTRKSVSADRLTDDRDEAIIDEDSVSWLHDIRYVLVVHVNCISI 488
G VD G ++ V T +V + L DD I +DS D++ L H +
Sbjct: 140 GTVDLILGEDYPGVMPLTDNTVEREHLIDDELVLITPQDSTLTFQDVK-ELAGHEGQPEV 198
Query: 487 AFLL--IIRTCRQLYSLSLLQFDFS*AAAFQEPSSDLRSFSVQ 365
F L + + R+ + LQ+ F F+ P L+++ V+
Sbjct: 199 RFALDSVEFSLRRFFQAYCLQYGFEPKVDFETPDPFLQTYLVR 241
>UniRef50_Q4CYW8 Cluster: Putative uncharacterized protein; n=3;
Trypanosoma|Rep: Putative uncharacterized protein -
Trypanosoma cruzi
Length = 435
Score = 34.7 bits (76), Expect = 2.7
Identities = 36/144 (25%), Positives = 60/144 (41%), Gaps = 7/144 (4%)
Frame = +2
Query: 158 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREA--EKSYSA 331
R+SG++ T+ P + A+ E + +A + +H E HA+ C A E+ S+
Sbjct: 30 RVSGLLFTVNPRQESKALRELQLYLHPLIADLEEAHKRVEEHADARGRCDNATTEEQSSS 89
Query: 332 KLGSPFSLAIALDTK---GPEIRTGLLEGGGSAEVELKK--GETIKLTTSSDYQEKGNAD 496
K+ + IA T E+ + GG E+++ + K S D EK + D
Sbjct: 90 KMSTDAGGKIAPSTSSLLAAELAEYITTRGGQRRHEMRRIPMKEEKSDVSDDEDEKKSTD 149
Query: 497 TIYVDYKNITNVVKPGNRIFIDDG 568
+ N +N NR D G
Sbjct: 150 NNNNNNNNNSNNNILRNRSSDDGG 173
>UniRef50_A5NL17 Cluster: ATP-dependent Clp protease, ATP-binding
subunit ClpA; n=1; Shewanella baltica OS223|Rep:
ATP-dependent Clp protease, ATP-binding subunit ClpA -
Shewanella baltica OS223
Length = 66
Score = 34.3 bits (75), Expect = 3.5
Identities = 20/51 (39%), Positives = 29/51 (56%), Gaps = 4/51 (7%)
Frame = +2
Query: 311 AEKSYSAKLGS-PFSLAIALDTKGP---EIRTGLLEGGGSAEVELKKGETI 451
AEK Y +G+ P + + K P EI G+LE GG A V++K+GE +
Sbjct: 3 AEKGYDKNMGARPMARVVTELIKRPLADEILFGVLESGGVAHVDVKEGELV 53
>UniRef50_Q8EYH8 Cluster: MutS-like mismatch repair protein,
ATPases; n=4; Leptospira|Rep: MutS-like mismatch repair
protein, ATPases - Leptospira interrogans
Length = 610
Score = 33.5 bits (73), Expect = 6.2
Identities = 49/171 (28%), Positives = 73/171 (42%), Gaps = 22/171 (12%)
Frame = +2
Query: 125 GLDIDSKSSYIRLSGIICTIG------PASR-NVAVLEKMMETGMNVARMNFSHGSHEYH 283
G ++ K++Y+R G+ + PAS+ ++ VL+ + T M N G ++
Sbjct: 441 GSNMSGKTTYLRTIGVASILSMAGGPVPASKFSLPVLK--IHTSMR-NEDNLEEGISFFY 497
Query: 284 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 463
AE +R E K K S L + KG R L G + ELKK TI T
Sbjct: 498 AE-VRRLSEIVKKIRDKNSSHLVLLDEI-LKGTNTRERSLACKGILK-ELKKNRTIVFVT 554
Query: 464 SSD-------------YQEKGNADTIYVDYKNITNVVKPGN--RIFIDDGL 571
S D +QE+ T+Y DYK +V+ N RI + +GL
Sbjct: 555 SHDLELAKVEGVILKHFQEEVLDGTMYFDYKIREGLVETSNALRILVQEGL 605
>UniRef50_Q2AHN9 Cluster: Radical SAM; n=1; Halothermothrix orenii H
168|Rep: Radical SAM - Halothermothrix orenii H 168
Length = 231
Score = 33.5 bits (73), Expect = 6.2
Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Frame = +2
Query: 359 IALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIY---VDYKNITN 529
IA+D K P R GLL G ++K+ I L ++ DY+ + Y D I
Sbjct: 120 IAMDIKAPFSRYGLLAGSSKYNNQIKESINILLNSNIDYEFRTTVIPGYHTENDLIKIAE 179
Query: 530 VVKPGNRIFIDD 565
++K R FI +
Sbjct: 180 LIKGAGRYFIQN 191
>UniRef50_Q6IKV8 Cluster: HDC11342; n=2; Drosophila melanogaster|Rep:
HDC11342 - Drosophila melanogaster (Fruit fly)
Length = 1115
Score = 33.5 bits (73), Expect = 6.2
Identities = 13/23 (56%), Positives = 17/23 (73%)
Frame = -1
Query: 744 STPCSTPKSRSDLSFSETAGRST 676
+TPCSTP+ DLSF E A ++T
Sbjct: 949 TTPCSTPRGEDDLSFKEGAPKTT 971
>UniRef50_Q3EBL2 Cluster: Uncharacterized protein At2g37440.1; n=3;
Arabidopsis thaliana|Rep: Uncharacterized protein
At2g37440.1 - Arabidopsis thaliana (Mouse-ear cress)
Length = 479
Score = 33.1 bits (72), Expect = 8.2
Identities = 18/40 (45%), Positives = 22/40 (55%)
Frame = -3
Query: 634 TSVFNGTRKSVSADRLTDDRDEAIIDEDSVSWLHDIRYVL 515
T +F TR S S+ D R E I+D D V WL D+ Y L
Sbjct: 276 TEIFKRTRFSRSSK---DSRPETIMDHDKVIWLGDLNYRL 312
>UniRef50_A5BAI3 Cluster: Putative uncharacterized protein; n=2;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 929
Score = 33.1 bits (72), Expect = 8.2
Identities = 29/102 (28%), Positives = 40/102 (39%)
Frame = +2
Query: 26 KMVYPTIHDGEIEAGAVEKPTVANVGSQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNV 205
K + PT++DG + G PT ++ GS + + S SY L ++ I P S
Sbjct: 694 KEIQPTVNDGAPDPGEESHPTASSGGSPVDDATCISA-SPFSYTELGEMLKRIPPGSDVA 752
Query: 206 AVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSA 331
KM E A M F E +AE S SA
Sbjct: 753 VPSAKMFE----AAEMTFVSQRINSEEELRLRLEQAEASLSA 790
>UniRef50_Q5JCZ5 Cluster: Putative uncharacterized protein; n=2;
Thermococcus kodakarensis KOD1|Rep: Putative
uncharacterized protein - Pyrococcus kodakaraensis
(Thermococcus kodakaraensis)
Length = 628
Score = 33.1 bits (72), Expect = 8.2
Identities = 47/200 (23%), Positives = 84/200 (42%), Gaps = 13/200 (6%)
Frame = +2
Query: 53 GEIEAGAVEKPTVANV----GSQLQHMCGLDIDS-----KSSYIRLSGIICTIGPASRNV 205
G+ G + PT ++ G+ QH L +S +Y + T+ P +V
Sbjct: 354 GKYYLGDISGPTQISIKFKAGAVGQHGFTLSFESHDAIMSKTYTTTKSVTYTVEPLPFSV 413
Query: 206 AVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF---SLAIALDTK 376
+ + + G N R++ S G +++ + E + SP+ S ++ + ++
Sbjct: 414 QMPSEW-QVGQNELRISESSGQSYLITAVLKDSQGNEVWSDSHAFSPYEAYSFSVNVPSE 472
Query: 377 GPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIF 556
G + L G A ++ I LTT EKG TI + +KN ++ V+ I
Sbjct: 473 G-QYTLELQWNGQVATYDVTVNPAITLTTKQLTVEKGGEGTIVLHFKNPSSDVQ-YYTIK 530
Query: 557 IDDGLI-SIICQSVSADTLT 613
+ G + S I QS+S LT
Sbjct: 531 VSGGFLPSEINQSISVGPLT 550
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 797,468,264
Number of Sequences: 1657284
Number of extensions: 16764042
Number of successful extensions: 58732
Number of sequences better than 10.0: 176
Number of HSP's better than 10.0 without gapping: 55457
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 58449
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 67085240885
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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