Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= epV30805
(789 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X56494-1|CAA39849.1| 531|Homo sapiens pyruvate kinase protein. 286 5e-77
M23725-1|AAA36449.1| 531|Homo sapiens M2-type pyruvate kinase p... 286 5e-77
BC012811-1|AAH12811.3| 531|Homo sapiens pyruvate kinase, muscle... 286 5e-77
BC007952-1|AAH07952.3| 531|Homo sapiens pyruvate kinase, muscle... 286 5e-77
BC007640-1|AAH07640.1| 531|Homo sapiens pyruvate kinase, muscle... 286 5e-77
BC000481-1|AAH00481.3| 531|Homo sapiens pyruvate kinase, muscle... 286 5e-77
AY352517-1|AAQ15274.1| 531|Homo sapiens pyruvate kinase, muscle... 286 5e-77
M26252-1|AAA36672.1| 531|Homo sapiens protein ( Human TCB gene ... 285 9e-77
AK222927-1|BAD96647.1| 531|Homo sapiens pyruvate kinase 3 isofo... 283 5e-76
BC035198-1|AAH35198.1| 531|Homo sapiens pyruvate kinase, muscle... 283 7e-76
M15465-1|AAA60104.1| 543|Homo sapiens pyruvate kinase protein. 275 1e-73
U47654-2|AAA92536.1| 566|Homo sapiens pyruvate kinase PK-L isoe... 272 9e-73
U47654-1|AAA92535.1| 587|Homo sapiens pyruvate kinase PK-R isoe... 272 9e-73
D13243-1|BAA02515.1| 599|Homo sapiens pyruvate kinase L protein. 272 9e-73
BC025737-1|AAH25737.1| 574|Homo sapiens pyruvate kinase, liver ... 272 9e-73
AY316591-1|AAP69527.1| 574|Homo sapiens pyruvate kinase, liver ... 272 9e-73
AL713999-33|CAI95102.1| 585|Homo sapiens pyruvate kinase, liver... 272 9e-73
AL713999-32|CAI95101.1| 565|Homo sapiens pyruvate kinase, liver... 272 9e-73
AB015983-1|BAA31706.1| 574|Homo sapiens pyruvate kinase L protein. 272 9e-73
BC019265-1|AAH19265.2| 343|Homo sapiens PKM2 protein protein. 93 1e-18
BC094767-1|AAH94767.1| 366|Homo sapiens PKM2 protein protein. 75 3e-13
BX538020-1|CAD97966.1| 1510|Homo sapiens hypothetical protein pr... 30 8.3
AB023164-1|BAA76791.3| 2330|Homo sapiens KIAA0947 protein protein. 30 8.3
>X56494-1|CAA39849.1| 531|Homo sapiens pyruvate kinase protein.
Length = 531
Score = 286 bits (702), Expect = 5e-77
Identities = 136/226 (60%), Positives = 176/226 (77%)
Frame = +2
Query: 110 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 289
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 290 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 469
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 470 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 649
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG LGS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 650 KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALH 787
KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +H
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVH 252
>M23725-1|AAA36449.1| 531|Homo sapiens M2-type pyruvate kinase
protein.
Length = 531
Score = 286 bits (702), Expect = 5e-77
Identities = 136/226 (60%), Positives = 176/226 (77%)
Frame = +2
Query: 110 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 289
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 290 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 469
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 470 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 649
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG LGS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 650 KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALH 787
KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +H
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVH 252
>BC012811-1|AAH12811.3| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 286 bits (702), Expect = 5e-77
Identities = 136/226 (60%), Positives = 176/226 (77%)
Frame = +2
Query: 110 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 289
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 290 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 469
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 470 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 649
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG LGS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 650 KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALH 787
KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +H
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVH 252
>BC007952-1|AAH07952.3| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 286 bits (702), Expect = 5e-77
Identities = 136/226 (60%), Positives = 176/226 (77%)
Frame = +2
Query: 110 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 289
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 290 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 469
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 470 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 649
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG LGS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 650 KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALH 787
KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +H
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVH 252
>BC007640-1|AAH07640.1| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 286 bits (702), Expect = 5e-77
Identities = 136/226 (60%), Positives = 176/226 (77%)
Frame = +2
Query: 110 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 289
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 290 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 469
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 470 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 649
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG LGS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 650 KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALH 787
KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +H
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVH 252
>BC000481-1|AAH00481.3| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 286 bits (702), Expect = 5e-77
Identities = 136/226 (60%), Positives = 176/226 (77%)
Frame = +2
Query: 110 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 289
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 290 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 469
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 470 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 649
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG LGS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 650 KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALH 787
KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +H
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVH 252
>AY352517-1|AAQ15274.1| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 286 bits (702), Expect = 5e-77
Identities = 136/226 (60%), Positives = 176/226 (77%)
Frame = +2
Query: 110 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 289
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 290 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 469
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 470 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 649
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG LGS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 650 KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALH 787
KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +H
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVH 252
>M26252-1|AAA36672.1| 531|Homo sapiens protein ( Human TCB gene
encoding cytosolic thyroid hormone-binding protein,
complete cds. ).
Length = 531
Score = 285 bits (700), Expect = 9e-77
Identities = 135/226 (59%), Positives = 176/226 (77%)
Frame = +2
Query: 110 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 289
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 290 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 469
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AE+ELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPYLYRPVAVALDTKGPEIRTGLIKGSGTAELELKKGATLKITLDN 146
Query: 470 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 649
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG LGS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 650 KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALH 787
KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +H
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVH 252
>AK222927-1|BAD96647.1| 531|Homo sapiens pyruvate kinase 3 isoform
1 variant protein.
Length = 531
Score = 283 bits (694), Expect = 5e-76
Identities = 135/223 (60%), Positives = 174/223 (78%)
Frame = +2
Query: 110 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 289
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 290 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 469
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 470 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 649
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG LGS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKRKGADFLVTEVENGGSLGSK 206
Query: 650 KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGA 778
KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR +
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAS 249
>BC035198-1|AAH35198.1| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 283 bits (693), Expect = 7e-76
Identities = 135/226 (59%), Positives = 175/226 (77%)
Frame = +2
Query: 110 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 289
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 290 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 469
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 470 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 649
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG L S+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLVSK 206
Query: 650 KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALH 787
KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +H
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVH 252
>M15465-1|AAA60104.1| 543|Homo sapiens pyruvate kinase protein.
Length = 543
Score = 275 bits (675), Expect = 1e-73
Identities = 133/226 (58%), Positives = 172/226 (76%), Gaps = 3/226 (1%)
Frame = +2
Query: 110 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 289
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 39 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 98
Query: 290 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 460
TI N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 99 TIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 155
Query: 461 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 640
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q +S + L +ENGG+L
Sbjct: 156 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKISPEGLVTQVENGGVL 215
Query: 641 GSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGA 778
GSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R +
Sbjct: 216 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKAS 261
>U47654-2|AAA92536.1| 566|Homo sapiens pyruvate kinase PK-L
isoenzyme protein.
Length = 566
Score = 272 bits (667), Expect = 9e-73
Identities = 131/226 (57%), Positives = 171/226 (75%), Gaps = 3/226 (1%)
Frame = +2
Query: 110 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 289
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 62 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 121
Query: 290 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 460
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 122 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 178
Query: 461 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 640
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L
Sbjct: 179 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 238
Query: 641 GSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGA 778
GSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R +
Sbjct: 239 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKAS 284
>U47654-1|AAA92535.1| 587|Homo sapiens pyruvate kinase PK-R
isoenzyme protein.
Length = 587
Score = 272 bits (667), Expect = 9e-73
Identities = 131/226 (57%), Positives = 171/226 (75%), Gaps = 3/226 (1%)
Frame = +2
Query: 110 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 289
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 83 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 142
Query: 290 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 460
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 143 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 199
Query: 461 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 640
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L
Sbjct: 200 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 259
Query: 641 GSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGA 778
GSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R +
Sbjct: 260 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKAS 305
>D13243-1|BAA02515.1| 599|Homo sapiens pyruvate kinase L protein.
Length = 599
Score = 272 bits (667), Expect = 9e-73
Identities = 131/226 (57%), Positives = 171/226 (75%), Gaps = 3/226 (1%)
Frame = +2
Query: 110 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 289
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 95 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 154
Query: 290 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 460
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 155 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 211
Query: 461 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 640
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L
Sbjct: 212 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 271
Query: 641 GSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGA 778
GSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R +
Sbjct: 272 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKAS 317
>BC025737-1|AAH25737.1| 574|Homo sapiens pyruvate kinase, liver and
RBC protein.
Length = 574
Score = 272 bits (667), Expect = 9e-73
Identities = 131/226 (57%), Positives = 171/226 (75%), Gaps = 3/226 (1%)
Frame = +2
Query: 110 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 289
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 70 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 129
Query: 290 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 460
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 130 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 186
Query: 461 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 640
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L
Sbjct: 187 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 246
Query: 641 GSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGA 778
GSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R +
Sbjct: 247 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKAS 292
>AY316591-1|AAP69527.1| 574|Homo sapiens pyruvate kinase, liver and
RBC protein.
Length = 574
Score = 272 bits (667), Expect = 9e-73
Identities = 131/226 (57%), Positives = 171/226 (75%), Gaps = 3/226 (1%)
Frame = +2
Query: 110 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 289
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 70 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 129
Query: 290 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 460
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 130 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 186
Query: 461 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 640
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L
Sbjct: 187 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 246
Query: 641 GSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGA 778
GSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R +
Sbjct: 247 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKAS 292
>AL713999-33|CAI95102.1| 585|Homo sapiens pyruvate kinase, liver
and RBC protein.
Length = 585
Score = 272 bits (667), Expect = 9e-73
Identities = 131/226 (57%), Positives = 171/226 (75%), Gaps = 3/226 (1%)
Frame = +2
Query: 110 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 289
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 81 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 140
Query: 290 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 460
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 141 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 197
Query: 461 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 640
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L
Sbjct: 198 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 257
Query: 641 GSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGA 778
GSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R +
Sbjct: 258 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKAS 303
>AL713999-32|CAI95101.1| 565|Homo sapiens pyruvate kinase, liver
and RBC protein.
Length = 565
Score = 272 bits (667), Expect = 9e-73
Identities = 131/226 (57%), Positives = 171/226 (75%), Gaps = 3/226 (1%)
Frame = +2
Query: 110 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 289
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 61 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 120
Query: 290 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 460
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 121 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 177
Query: 461 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 640
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L
Sbjct: 178 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 237
Query: 641 GSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGA 778
GSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R +
Sbjct: 238 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKAS 283
>AB015983-1|BAA31706.1| 574|Homo sapiens pyruvate kinase L protein.
Length = 574
Score = 272 bits (667), Expect = 9e-73
Identities = 131/226 (57%), Positives = 171/226 (75%), Gaps = 3/226 (1%)
Frame = +2
Query: 110 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 289
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 70 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 129
Query: 290 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 460
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 130 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 186
Query: 461 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 640
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L
Sbjct: 187 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 246
Query: 641 GSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGA 778
GSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R +
Sbjct: 247 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKAS 292
>BC019265-1|AAH19265.2| 343|Homo sapiens PKM2 protein protein.
Length = 343
Score = 93.1 bits (221), Expect = 1e-18
Identities = 44/63 (69%), Positives = 49/63 (77%)
Frame = +2
Query: 599 ADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGA 778
AD L +ENGG LGS+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR +
Sbjct: 2 ADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAS 61
Query: 779 ALH 787
+H
Sbjct: 62 DVH 64
>BC094767-1|AAH94767.1| 366|Homo sapiens PKM2 protein protein.
Length = 366
Score = 74.9 bits (176), Expect = 3e-13
Identities = 35/48 (72%), Positives = 39/48 (81%)
Frame = +2
Query: 644 SRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALH 787
S+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +H
Sbjct: 40 SKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVH 87
>BX538020-1|CAD97966.1| 1510|Homo sapiens hypothetical protein
protein.
Length = 1510
Score = 30.3 bits (65), Expect = 8.3
Identities = 14/43 (32%), Positives = 23/43 (53%)
Frame = -1
Query: 756 AKIISTPCSTPKSRSDLSFSETAGRSTGMPGRLTPFRDPSIPP 628
A +I+TP T + S L S + G+++PFR+ +PP
Sbjct: 881 APLIATPPRTSQPLSPLISSSSPSSPASPVGQVSPFRETPVPP 923
>AB023164-1|BAA76791.3| 2330|Homo sapiens KIAA0947 protein protein.
Length = 2330
Score = 30.3 bits (65), Expect = 8.3
Identities = 14/43 (32%), Positives = 23/43 (53%)
Frame = -1
Query: 756 AKIISTPCSTPKSRSDLSFSETAGRSTGMPGRLTPFRDPSIPP 628
A +I+TP T + S L S + G+++PFR+ +PP
Sbjct: 1701 APLIATPPRTSQPLSPLISSSSPSSPASPVGQVSPFRETPVPP 1743
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 115,671,979
Number of Sequences: 237096
Number of extensions: 2485963
Number of successful extensions: 7329
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 6994
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7319
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9646050614
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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