BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= epV30683 (722 letters) Database: human 237,096 sequences; 76,859,062 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BC019320-1|AAH19320.2| 427|Homo sapiens pseudouridylate synthas... 42 0.002 BC009505-1|AAH09505.2| 427|Homo sapiens pseudouridylate synthas... 42 0.002 BC002901-1|AAH02901.1| 399|Homo sapiens pseudouridylate synthas... 42 0.002 AF116238-1|AAD21042.1| 365|Homo sapiens pseudouridine synthase ... 42 0.002 J03250-1|AAA61207.1| 765|Homo sapiens TOP1 protein. 32 1.8 U07806-1|AAB60380.1| 761|Homo sapiens DNA topoisomerase I protein. 31 5.5 U07804-1|AAB60379.1| 761|Homo sapiens DNA topoisomerase I protein. 31 5.5 M60706-1|AAA61206.1| 765|Homo sapiens topoisomerase I protein. 31 5.5 BC092404-1|AAH92404.1| 881|Homo sapiens Rap guanine nucleotide ... 31 5.5 AL035652-1|CAI19767.1| 765|Homo sapiens topoisomerase (DNA) I p... 31 5.5 AL022394-1|CAI42886.1| 765|Homo sapiens topoisomerase (DNA) I p... 31 5.5 U78168-1|AAD12740.1| 881|Homo sapiens cAMP-regulated guanine nu... 30 7.3 BC017728-1|AAH17728.1| 881|Homo sapiens Rap guanine nucleotide ... 30 7.3 AF103905-1|AAC83381.1| 881|Homo sapiens Rap1 guanine-nucleotide... 30 7.3 >BC019320-1|AAH19320.2| 427|Homo sapiens pseudouridylate synthase 1 protein. Length = 427 Score = 42.3 bits (95), Expect = 0.002 Identities = 21/43 (48%), Positives = 31/43 (72%), Gaps = 1/43 (2%) Frame = +2 Query: 596 VSLKLPLEVNV-EEINKRLPETIKVFAVKRVTNRFNSKSKCNA 721 VSLK+ L ++ E+IN LP I++ +KRVT FNSK++C+A Sbjct: 156 VSLKVWLIDDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDA 198 Score = 37.5 bits (83), Expect = 0.048 Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 3/70 (4%) Frame = +3 Query: 372 ERIKRKKMAMLLGYSGVEYYGMQRNPG---VQTIXXXXXXXXXXXXYITQEDFENAQNAQ 542 E+ ++K+ +L+ YSG Y+GMQRN G +TI I + E+ + Sbjct: 79 EKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMS 138 Query: 543 FQRSSRD*QG 572 FQR +R +G Sbjct: 139 FQRCARTDKG 148 >BC009505-1|AAH09505.2| 427|Homo sapiens pseudouridylate synthase 1 protein. Length = 427 Score = 42.3 bits (95), Expect = 0.002 Identities = 21/43 (48%), Positives = 31/43 (72%), Gaps = 1/43 (2%) Frame = +2 Query: 596 VSLKLPLEVNV-EEINKRLPETIKVFAVKRVTNRFNSKSKCNA 721 VSLK+ L ++ E+IN LP I++ +KRVT FNSK++C+A Sbjct: 156 VSLKVWLIDDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDA 198 Score = 37.5 bits (83), Expect = 0.048 Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 3/70 (4%) Frame = +3 Query: 372 ERIKRKKMAMLLGYSGVEYYGMQRNPG---VQTIXXXXXXXXXXXXYITQEDFENAQNAQ 542 E+ ++K+ +L+ YSG Y+GMQRN G +TI I + E+ + Sbjct: 79 EKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMS 138 Query: 543 FQRSSRD*QG 572 FQR +R +G Sbjct: 139 FQRCARTDKG 148 >BC002901-1|AAH02901.1| 399|Homo sapiens pseudouridylate synthase 1 protein. Length = 399 Score = 42.3 bits (95), Expect = 0.002 Identities = 21/43 (48%), Positives = 31/43 (72%), Gaps = 1/43 (2%) Frame = +2 Query: 596 VSLKLPLEVNV-EEINKRLPETIKVFAVKRVTNRFNSKSKCNA 721 VSLK+ L ++ E+IN LP I++ +KRVT FNSK++C+A Sbjct: 128 VSLKVWLIDDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDA 170 Score = 37.5 bits (83), Expect = 0.048 Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 3/70 (4%) Frame = +3 Query: 372 ERIKRKKMAMLLGYSGVEYYGMQRNPG---VQTIXXXXXXXXXXXXYITQEDFENAQNAQ 542 E+ ++K+ +L+ YSG Y+GMQRN G +TI I + E+ + Sbjct: 51 EKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMS 110 Query: 543 FQRSSRD*QG 572 FQR +R +G Sbjct: 111 FQRCARTDKG 120 >AF116238-1|AAD21042.1| 365|Homo sapiens pseudouridine synthase 1 protein. Length = 365 Score = 42.3 bits (95), Expect = 0.002 Identities = 21/43 (48%), Positives = 31/43 (72%), Gaps = 1/43 (2%) Frame = +2 Query: 596 VSLKLPLEVNV-EEINKRLPETIKVFAVKRVTNRFNSKSKCNA 721 VSLK+ L ++ E+IN LP I++ +KRVT FNSK++C+A Sbjct: 94 VSLKVWLIDDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDA 136 Score = 37.5 bits (83), Expect = 0.048 Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 3/70 (4%) Frame = +3 Query: 372 ERIKRKKMAMLLGYSGVEYYGMQRNPG---VQTIXXXXXXXXXXXXYITQEDFENAQNAQ 542 E+ ++K+ +L+ YSG Y+GMQRN G +TI I + E+ + Sbjct: 17 EKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMS 76 Query: 543 FQRSSRD*QG 572 FQR +R +G Sbjct: 77 FQRCARTDKG 86 >J03250-1|AAA61207.1| 765|Homo sapiens TOP1 protein. Length = 765 Score = 32.3 bits (70), Expect = 1.8 Identities = 16/48 (33%), Positives = 27/48 (56%) Frame = +3 Query: 252 KDEENKSIDIVPNKLLTRYNKRRAHRDWETKPPGEIKKPYERIKRKKM 395 +DE++ +D P K+ T K+ R E + G++KKP + K KK+ Sbjct: 140 RDEDD--VDYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKV 185 >U07806-1|AAB60380.1| 761|Homo sapiens DNA topoisomerase I protein. Length = 761 Score = 30.7 bits (66), Expect = 5.5 Identities = 16/48 (33%), Positives = 26/48 (54%) Frame = +3 Query: 252 KDEENKSIDIVPNKLLTRYNKRRAHRDWETKPPGEIKKPYERIKRKKM 395 +DE++ D P K+ T K+ R E + G++KKP + K KK+ Sbjct: 136 RDEDDA--DYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKV 181 >U07804-1|AAB60379.1| 761|Homo sapiens DNA topoisomerase I protein. Length = 761 Score = 30.7 bits (66), Expect = 5.5 Identities = 16/48 (33%), Positives = 26/48 (54%) Frame = +3 Query: 252 KDEENKSIDIVPNKLLTRYNKRRAHRDWETKPPGEIKKPYERIKRKKM 395 +DE++ D P K+ T K+ R E + G++KKP + K KK+ Sbjct: 136 RDEDDA--DYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKV 181 >M60706-1|AAA61206.1| 765|Homo sapiens topoisomerase I protein. Length = 765 Score = 30.7 bits (66), Expect = 5.5 Identities = 16/48 (33%), Positives = 26/48 (54%) Frame = +3 Query: 252 KDEENKSIDIVPNKLLTRYNKRRAHRDWETKPPGEIKKPYERIKRKKM 395 +DE++ D P K+ T K+ R E + G++KKP + K KK+ Sbjct: 140 RDEDDA--DYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKV 185 >BC092404-1|AAH92404.1| 881|Homo sapiens Rap guanine nucleotide exchange factor (GEF) 3 protein. Length = 881 Score = 30.7 bits (66), Expect = 5.5 Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 2/49 (4%) Frame = -3 Query: 351 LEVWSPNRD--VPGVCCTSLIAYSALYRLTYFLHLSLRRQLPLRTASVR 211 L VW PN+D +PG C + Y + H L QLP+ TASVR Sbjct: 494 LPVWLPNQDEPLPGSSCAIQVGDKVPYDICRPDHSVLTMQLPV-TASVR 541 >AL035652-1|CAI19767.1| 765|Homo sapiens topoisomerase (DNA) I protein. Length = 765 Score = 30.7 bits (66), Expect = 5.5 Identities = 16/48 (33%), Positives = 26/48 (54%) Frame = +3 Query: 252 KDEENKSIDIVPNKLLTRYNKRRAHRDWETKPPGEIKKPYERIKRKKM 395 +DE++ D P K+ T K+ R E + G++KKP + K KK+ Sbjct: 140 RDEDDA--DYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKV 185 >AL022394-1|CAI42886.1| 765|Homo sapiens topoisomerase (DNA) I protein. Length = 765 Score = 30.7 bits (66), Expect = 5.5 Identities = 16/48 (33%), Positives = 26/48 (54%) Frame = +3 Query: 252 KDEENKSIDIVPNKLLTRYNKRRAHRDWETKPPGEIKKPYERIKRKKM 395 +DE++ D P K+ T K+ R E + G++KKP + K KK+ Sbjct: 140 RDEDDA--DYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKV 185 >U78168-1|AAD12740.1| 881|Homo sapiens cAMP-regulated guanine nucleotide exchange factor I protein. Length = 881 Score = 30.3 bits (65), Expect = 7.3 Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 2/49 (4%) Frame = -3 Query: 351 LEVWSPNRD--VPGVCCTSLIAYSALYRLTYFLHLSLRRQLPLRTASVR 211 L VW PN+D +PG C + Y + H L QLP+ TASVR Sbjct: 494 LPVWLPNQDEPLPGSSCAIQVGDKVPYDICRPDHSVLTLQLPV-TASVR 541 >BC017728-1|AAH17728.1| 881|Homo sapiens Rap guanine nucleotide exchange factor (GEF) 3 protein. Length = 881 Score = 30.3 bits (65), Expect = 7.3 Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 2/49 (4%) Frame = -3 Query: 351 LEVWSPNRD--VPGVCCTSLIAYSALYRLTYFLHLSLRRQLPLRTASVR 211 L VW PN+D +PG C + Y + H L QLP+ TASVR Sbjct: 494 LPVWLPNQDEPLPGSSCAIQVGDKVPYDICRPDHSVLTLQLPV-TASVR 541 >AF103905-1|AAC83381.1| 881|Homo sapiens Rap1 guanine-nucleotide exchange factor protein. Length = 881 Score = 30.3 bits (65), Expect = 7.3 Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 2/49 (4%) Frame = -3 Query: 351 LEVWSPNRD--VPGVCCTSLIAYSALYRLTYFLHLSLRRQLPLRTASVR 211 L VW PN+D +PG C + Y + H L QLP+ TASVR Sbjct: 494 LPVWLPNQDEPLPGSSCAIQVGDKVPYDICRPDHSVLTLQLPV-TASVR 541 Database: human Posted date: Oct 23, 2007 1:18 PM Number of letters in database: 76,859,062 Number of sequences in database: 237,096 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 98,760,791 Number of Sequences: 237096 Number of extensions: 2056512 Number of successful extensions: 4161 Number of sequences better than 10.0: 14 Number of HSP's better than 10.0 without gapping: 4035 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4159 length of database: 76,859,062 effective HSP length: 88 effective length of database: 55,994,614 effective search space used: 8511181328 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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