SilkBase IMG001 IMG002 IMG003 IMG005 IMG006 IMG007 IMG008 IMG009 kuwako IMG010 IMG011 IMG012

Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= epV30573
         (516 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

X72389-1|CAA51082.1|  393|Homo sapiens 4-hydroxyphenylpyruvate d...   208   1e-53
U29895-1|AAC73008.1|  393|Homo sapiens 4-hydroxyphenylpyruvate-d...   208   1e-53
D31628-1|BAA06498.1|  393|Homo sapiens 4-hydroxyphenylpyruvic ac...   208   1e-53
BC024287-1|AAH24287.1|  393|Homo sapiens 4-hydroxyphenylpyruvate...   208   1e-53
BC007293-1|AAH07293.1|  371|Homo sapiens 4-hydroxyphenylpyruvate...    37   0.036
AL359540-1|CAI21712.1|  371|Homo sapiens 4-hydroxyphenylpyruvate...    37   0.036
BC111944-1|AAI11945.1|  304|Homo sapiens family with sequence si...    31   2.4  
BC093665-1|AAH93665.1|  304|Homo sapiens family with sequence si...    31   2.4  
AK126284-1|BAC86515.1|  304|Homo sapiens n 2 (Gab2).  protein.         31   2.4  
DQ109808-1|AAZ83370.1| 2479|Homo sapiens nephrocystin-6 protein.       30   4.2  
AF273044-1|AAG34904.1|  761|Homo sapiens CTCL tumor antigen se2-...    30   4.2  
AB002371-1|BAA20828.2| 1540|Homo sapiens KIAA0373 protein.             30   4.2  
BC117429-1|AAI17430.1|  725|Homo sapiens MAK10 homolog, amino-ac...    29   9.7  
BC117427-1|AAI17428.1|  725|Homo sapiens MAK10 homolog, amino-ac...    29   9.7  
AL353743-7|CAI12659.1|  725|Homo sapiens MAK10 homolog, amino-ac...    29   9.7  
AL161453-3|CAI16313.1|  725|Homo sapiens MAK10 homolog, amino-ac...    29   9.7  
AL161447-5|CAH73155.1|  725|Homo sapiens MAK10 homolog, amino-ac...    29   9.7  

>X72389-1|CAA51082.1|  393|Homo sapiens 4-hydroxyphenylpyruvate
           dioxygenase protein.
          Length = 393

 Score =  208 bits (507), Expect = 1e-53
 Identities = 89/161 (55%), Positives = 121/161 (75%)
 Frame = +3

Query: 27  MTTYTDKGRKPDDGRFLAFDHVTFWVSNAKQAASYYVTRFGFEPLAYSGLETGSRQISSH 206
           MTTY+DKG KP+ GRFL F  VTFWV NAKQAAS+Y ++ GFEPLAY GLETGSR++ SH
Sbjct: 1   MTTYSDKGAKPERGRFLHFHSVTFWVGNAKQAASFYCSKMGFEPLAYRGLETGSREVVSH 60

Query: 207 AVRMNKIIFVFQAQYEPMETEFVNEVAIHGDFVKDVAFQVENLDYILEYARKQGAKVVKD 386
            ++  KI+FV  +   P   E  + +  HGD VKD+AF+VE+ DYI++ AR++GAK++++
Sbjct: 61  VIKQGKIVFVLSSALNPWNKEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAKIMRE 120

Query: 387 LWEEKDQYGVVRMATLKTYGSNTHTLVDRSKYTGPFLPGYQ 509
            W E+D++G V+ A L+TYG  THTLV++  Y G FLPGY+
Sbjct: 121 PWVEQDKFGKVKFAVLQTYGDTTHTLVEKMNYIGQFLPGYE 161


>U29895-1|AAC73008.1|  393|Homo sapiens
           4-hydroxyphenylpyruvate-dioxygenase protein.
          Length = 393

 Score =  208 bits (507), Expect = 1e-53
 Identities = 89/161 (55%), Positives = 121/161 (75%)
 Frame = +3

Query: 27  MTTYTDKGRKPDDGRFLAFDHVTFWVSNAKQAASYYVTRFGFEPLAYSGLETGSRQISSH 206
           MTTY+DKG KP+ GRFL F  VTFWV NAKQAAS+Y ++ GFEPLAY GLETGSR++ SH
Sbjct: 1   MTTYSDKGAKPERGRFLHFHSVTFWVGNAKQAASFYCSKMGFEPLAYRGLETGSREVVSH 60

Query: 207 AVRMNKIIFVFQAQYEPMETEFVNEVAIHGDFVKDVAFQVENLDYILEYARKQGAKVVKD 386
            ++  KI+FV  +   P   E  + +  HGD VKD+AF+VE+ DYI++ AR++GAK++++
Sbjct: 61  VIKQGKIVFVLSSALNPWNKEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAKIMRE 120

Query: 387 LWEEKDQYGVVRMATLKTYGSNTHTLVDRSKYTGPFLPGYQ 509
            W E+D++G V+ A L+TYG  THTLV++  Y G FLPGY+
Sbjct: 121 PWVEQDKFGKVKFAVLQTYGDTTHTLVEKMNYIGQFLPGYE 161


>D31628-1|BAA06498.1|  393|Homo sapiens 4-hydroxyphenylpyruvic acid
           dioxgenase (HPD) protein.
          Length = 393

 Score =  208 bits (507), Expect = 1e-53
 Identities = 89/161 (55%), Positives = 121/161 (75%)
 Frame = +3

Query: 27  MTTYTDKGRKPDDGRFLAFDHVTFWVSNAKQAASYYVTRFGFEPLAYSGLETGSRQISSH 206
           MTTY+DKG KP+ GRFL F  VTFWV NAKQAAS+Y ++ GFEPLAY GLETGSR++ SH
Sbjct: 1   MTTYSDKGAKPERGRFLHFHSVTFWVGNAKQAASFYCSKMGFEPLAYRGLETGSREVVSH 60

Query: 207 AVRMNKIIFVFQAQYEPMETEFVNEVAIHGDFVKDVAFQVENLDYILEYARKQGAKVVKD 386
            ++  KI+FV  +   P   E  + +  HGD VKD+AF+VE+ DYI++ AR++GAK++++
Sbjct: 61  VIKQGKIVFVLSSALNPWNKEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAKIMRE 120

Query: 387 LWEEKDQYGVVRMATLKTYGSNTHTLVDRSKYTGPFLPGYQ 509
            W E+D++G V+ A L+TYG  THTLV++  Y G FLPGY+
Sbjct: 121 PWVEQDKFGKVKFAVLQTYGDTTHTLVEKMNYIGQFLPGYE 161


>BC024287-1|AAH24287.1|  393|Homo sapiens 4-hydroxyphenylpyruvate
           dioxygenase protein.
          Length = 393

 Score =  208 bits (507), Expect = 1e-53
 Identities = 89/161 (55%), Positives = 121/161 (75%)
 Frame = +3

Query: 27  MTTYTDKGRKPDDGRFLAFDHVTFWVSNAKQAASYYVTRFGFEPLAYSGLETGSRQISSH 206
           MTTY+DKG KP+ GRFL F  VTFWV NAKQAAS+Y ++ GFEPLAY GLETGSR++ SH
Sbjct: 1   MTTYSDKGAKPERGRFLHFHSVTFWVGNAKQAASFYCSKMGFEPLAYRGLETGSREVVSH 60

Query: 207 AVRMNKIIFVFQAQYEPMETEFVNEVAIHGDFVKDVAFQVENLDYILEYARKQGAKVVKD 386
            ++  KI+FV  +   P   E  + +  HGD VKD+AF+VE+ DYI++ AR++GAK++++
Sbjct: 61  VIKQGKIVFVLSSALNPWNKEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAKIMRE 120

Query: 387 LWEEKDQYGVVRMATLKTYGSNTHTLVDRSKYTGPFLPGYQ 509
            W E+D++G V+ A L+TYG  THTLV++  Y G FLPGY+
Sbjct: 121 PWVEQDKFGKVKFAVLQTYGDTTHTLVEKMNYIGQFLPGYE 161


>BC007293-1|AAH07293.1|  371|Homo sapiens 4-hydroxyphenylpyruvate
           dioxygenase-like protein.
          Length = 371

 Score = 37.1 bits (82), Expect = 0.036
 Identities = 35/142 (24%), Positives = 58/142 (40%), Gaps = 1/142 (0%)
 Frame = +3

Query: 87  HVTFWVSNAKQAASYYVTRFGFEPLAYSGLETGSRQISSHAVRMNKIIFVFQAQYEPMET 266
           H+ F V   +  A      FGF+PLA   ++ G RQ+   A+R    +F+        E 
Sbjct: 10  HIAFHVPAGQPLARNLQRLFGFQPLASREVD-GWRQL---ALRSGDAVFLVNEGAGSGEP 65

Query: 267 EFVNEVAIHGDFVKDVAFQVENLDYILEYARKQGAKVVKDLWEEKDQYGVVRMATLKT-Y 443
            +  +         ++ F V +           G  V       +D  G    A + +  
Sbjct: 66  LYGLDPRHAVPSATNLCFDVADAGAATRELAALGCSVPVPPVRVRDAQGAATYAVVSSPA 125

Query: 444 GSNTHTLVDRSKYTGPFLPGYQ 509
           G  + TL++R+ Y GPFLPG++
Sbjct: 126 GILSLTLLERAGYRGPFLPGFR 147


>AL359540-1|CAI21712.1|  371|Homo sapiens 4-hydroxyphenylpyruvate
           dioxygenase-like protein.
          Length = 371

 Score = 37.1 bits (82), Expect = 0.036
 Identities = 35/142 (24%), Positives = 58/142 (40%), Gaps = 1/142 (0%)
 Frame = +3

Query: 87  HVTFWVSNAKQAASYYVTRFGFEPLAYSGLETGSRQISSHAVRMNKIIFVFQAQYEPMET 266
           H+ F V   +  A      FGF+PLA   ++ G RQ+   A+R    +F+        E 
Sbjct: 10  HIAFHVPAGQPLARNLQRLFGFQPLASREVD-GWRQL---ALRSGDAVFLVNEGAGSGEP 65

Query: 267 EFVNEVAIHGDFVKDVAFQVENLDYILEYARKQGAKVVKDLWEEKDQYGVVRMATLKT-Y 443
            +  +         ++ F V +           G  V       +D  G    A + +  
Sbjct: 66  LYGLDPRHAVPSATNLCFDVADAGAATRELAALGCSVPVPPVRVRDAQGAATYAVVSSPA 125

Query: 444 GSNTHTLVDRSKYTGPFLPGYQ 509
           G  + TL++R+ Y GPFLPG++
Sbjct: 126 GILSLTLLERAGYRGPFLPGFR 147


>BC111944-1|AAI11945.1|  304|Homo sapiens family with sequence
           similarity 92, member B protein.
          Length = 304

 Score = 31.1 bits (67), Expect = 2.4
 Identities = 14/48 (29%), Positives = 27/48 (56%)
 Frame = +3

Query: 240 QAQYEPMETEFVNEVAIHGDFVKDVAFQVENLDYILEYARKQGAKVVK 383
           QAQ E +ET+ VN + ++G  +K    +++   ++  +  KQ  K+ K
Sbjct: 83  QAQVERLETKVVNPLKLYGAQIKQTRAEIKKFKHVQNHEIKQLEKLEK 130


>BC093665-1|AAH93665.1|  304|Homo sapiens family with sequence
           similarity 92, member B protein.
          Length = 304

 Score = 31.1 bits (67), Expect = 2.4
 Identities = 14/48 (29%), Positives = 27/48 (56%)
 Frame = +3

Query: 240 QAQYEPMETEFVNEVAIHGDFVKDVAFQVENLDYILEYARKQGAKVVK 383
           QAQ E +ET+ VN + ++G  +K    +++   ++  +  KQ  K+ K
Sbjct: 83  QAQVERLETKVVNPLKLYGAQIKQTRAEIKKFKHVQNHEIKQLEKLEK 130


>AK126284-1|BAC86515.1|  304|Homo sapiens n 2 (Gab2).  protein.
          Length = 304

 Score = 31.1 bits (67), Expect = 2.4
 Identities = 14/48 (29%), Positives = 27/48 (56%)
 Frame = +3

Query: 240 QAQYEPMETEFVNEVAIHGDFVKDVAFQVENLDYILEYARKQGAKVVK 383
           QAQ E +ET+ VN + ++G  +K    +++   ++  +  KQ  K+ K
Sbjct: 83  QAQVERLETKVVNPLKLYGAQIKQTRAEIKKFKHVQNHEIKQLEKLEK 130


>DQ109808-1|AAZ83370.1| 2479|Homo sapiens nephrocystin-6 protein.
          Length = 2479

 Score = 30.3 bits (65), Expect = 4.2
 Identities = 19/79 (24%), Positives = 40/79 (50%)
 Frame = +3

Query: 168  SGLETGSRQISSHAVRMNKIIFVFQAQYEPMETEFVNEVAIHGDFVKDVAFQVENLDYIL 347
            S L    +++S    R  +I  +   ++E ++ +       H D VK V  +VE+L Y+L
Sbjct: 1638 SSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQEN---HEDEVKKVKAEVEDLKYLL 1694

Query: 348  EYARKQGAKVVKDLWEEKD 404
            + ++K+   +  +L  +K+
Sbjct: 1695 DQSQKESQCLKSELQAQKE 1713


>AF273044-1|AAG34904.1|  761|Homo sapiens CTCL tumor antigen se2-2
           protein.
          Length = 761

 Score = 30.3 bits (65), Expect = 4.2
 Identities = 19/79 (24%), Positives = 40/79 (50%)
 Frame = +3

Query: 168 SGLETGSRQISSHAVRMNKIIFVFQAQYEPMETEFVNEVAIHGDFVKDVAFQVENLDYIL 347
           S L    +++S    R  +I  +   ++E ++ +       H D VK V  +VE+L Y+L
Sbjct: 13  SSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQEN---HEDEVKKVKAEVEDLKYLL 69

Query: 348 EYARKQGAKVVKDLWEEKD 404
           + ++K+   +  +L  +K+
Sbjct: 70  DQSQKESQCLKSELQAQKE 88


>AB002371-1|BAA20828.2| 1540|Homo sapiens KIAA0373 protein.
          Length = 1540

 Score = 30.3 bits (65), Expect = 4.2
 Identities = 19/79 (24%), Positives = 40/79 (50%)
 Frame = +3

Query: 168 SGLETGSRQISSHAVRMNKIIFVFQAQYEPMETEFVNEVAIHGDFVKDVAFQVENLDYIL 347
           S L    +++S    R  +I  +   ++E ++ +       H D VK V  +VE+L Y+L
Sbjct: 699 SSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQEN---HEDEVKKVKAEVEDLKYLL 755

Query: 348 EYARKQGAKVVKDLWEEKD 404
           + ++K+   +  +L  +K+
Sbjct: 756 DQSQKESQCLKSELQAQKE 774


>BC117429-1|AAI17430.1|  725|Homo sapiens MAK10 homolog, amino-acid
           N-acetyltransferase subunit, (S. cerevisiae) protein.
          Length = 725

 Score = 29.1 bits (62), Expect = 9.7
 Identities = 14/42 (33%), Positives = 22/42 (52%)
 Frame = -2

Query: 353 ILQYVVQVFHLEGYVFHEVTMNCDFVYEFGFHWLILRLKHED 228
           ++QY++  F LE Y  HE      ++ EF + WL+  L   D
Sbjct: 500 MIQYLLSGFELELYSMHEYYYIYWYLSEFLYAWLMSTLSRAD 541


>BC117427-1|AAI17428.1|  725|Homo sapiens MAK10 homolog, amino-acid
           N-acetyltransferase subunit, (S. cerevisiae) protein.
          Length = 725

 Score = 29.1 bits (62), Expect = 9.7
 Identities = 14/42 (33%), Positives = 22/42 (52%)
 Frame = -2

Query: 353 ILQYVVQVFHLEGYVFHEVTMNCDFVYEFGFHWLILRLKHED 228
           ++QY++  F LE Y  HE      ++ EF + WL+  L   D
Sbjct: 500 MIQYLLSGFELELYSMHEYYYIYWYLSEFLYAWLMSTLSRAD 541


>AL353743-7|CAI12659.1|  725|Homo sapiens MAK10 homolog, amino-acid
           N-acetyltransferase subunit, (S. cerevisiae) protein.
          Length = 725

 Score = 29.1 bits (62), Expect = 9.7
 Identities = 14/42 (33%), Positives = 22/42 (52%)
 Frame = -2

Query: 353 ILQYVVQVFHLEGYVFHEVTMNCDFVYEFGFHWLILRLKHED 228
           ++QY++  F LE Y  HE      ++ EF + WL+  L   D
Sbjct: 500 MIQYLLSGFELELYSMHEYYYIYWYLSEFLYAWLMSTLSRAD 541


>AL161453-3|CAI16313.1|  725|Homo sapiens MAK10 homolog, amino-acid
           N-acetyltransferase subunit, (S. cerevisiae) protein.
          Length = 725

 Score = 29.1 bits (62), Expect = 9.7
 Identities = 14/42 (33%), Positives = 22/42 (52%)
 Frame = -2

Query: 353 ILQYVVQVFHLEGYVFHEVTMNCDFVYEFGFHWLILRLKHED 228
           ++QY++  F LE Y  HE      ++ EF + WL+  L   D
Sbjct: 500 MIQYLLSGFELELYSMHEYYYIYWYLSEFLYAWLMSTLSRAD 541


>AL161447-5|CAH73155.1|  725|Homo sapiens MAK10 homolog, amino-acid
           N-acetyltransferase subunit, (S. cerevisiae) protein.
          Length = 725

 Score = 29.1 bits (62), Expect = 9.7
 Identities = 14/42 (33%), Positives = 22/42 (52%)
 Frame = -2

Query: 353 ILQYVVQVFHLEGYVFHEVTMNCDFVYEFGFHWLILRLKHED 228
           ++QY++  F LE Y  HE      ++ EF + WL+  L   D
Sbjct: 500 MIQYLLSGFELELYSMHEYYYIYWYLSEFLYAWLMSTLSRAD 541


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 78,404,311
Number of Sequences: 237096
Number of extensions: 1605036
Number of successful extensions: 3269
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 3203
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3267
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4876707572
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

- SilkBase 1999-2023 -