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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= epV30566
         (516 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P55072 Cluster: Transitional endoplasmic reticulum ATPa...   225   4e-58
UniRef50_A4ICJ9 Cluster: Transitional endoplasmic reticulum ATPa...   163   2e-39
UniRef50_Q4Y788 Cluster: Cell division cycle protein 48 homologu...   151   9e-36
UniRef50_UPI0000E4A84B Cluster: PREDICTED: similar to valosin; n...   135   6e-31
UniRef50_A0EEE7 Cluster: Chromosome undetermined scaffold_91, wh...   105   8e-22
UniRef50_Q4YQQ6 Cluster: Cell division cycle ATPase, putative; n...    70   4e-11
UniRef50_A5KAB5 Cluster: Cell division cycle ATPase, putative; n...    64   2e-09
UniRef50_Q7QWL6 Cluster: GLP_762_31096_33708; n=1; Giardia lambl...    61   1e-08
UniRef50_A7AVE1 Cluster: Cell division cycle protein ATPase, put...    50   2e-05
UniRef50_Q4MZM6 Cluster: Cell division cycle protein 48, putativ...    49   7e-05
UniRef50_Q1JSD1 Cluster: Transitional endoplasmic reticulum ATPa...    49   7e-05
UniRef50_Q4UBT9 Cluster: Cell divison cycle CDC48 homologue, put...    47   3e-04
UniRef50_A2FWK7 Cluster: ATPase, AAA family protein; n=1; Tricho...    35   0.96 
UniRef50_UPI0000499E59 Cluster: hypothetical protein 73.t00008; ...    33   2.9  
UniRef50_Q7QTA1 Cluster: GLP_15_26945_31573; n=3; root|Rep: GLP_...    33   2.9  
UniRef50_Q28VJ3 Cluster: Putative uncharacterized protein; n=1; ...    33   5.1  
UniRef50_Q4E0K4 Cluster: Ubiquitin hydrolase, putative; n=3; Try...    32   8.9  
UniRef50_A6R127 Cluster: Putative uncharacterized protein; n=1; ...    32   8.9  

>UniRef50_P55072 Cluster: Transitional endoplasmic reticulum ATPase
           (TER ATPase) (15S Mg(2+)- ATPase p97 subunit); n=169;
           Eukaryota|Rep: Transitional endoplasmic reticulum ATPase
           (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) - Homo
           sapiens (Human)
          Length = 806

 Score =  225 bits (551), Expect = 4e-58
 Identities = 104/147 (70%), Positives = 124/147 (84%)
 Frame = +2

Query: 71  ADNKSPDDLSTAILRRKDRPNRLIVEEAVSDDNSVVALSQAKMEQLQLFRGDTVLLKGKR 250
           AD+K  DDLSTAIL++K+RPNRLIV+EA+++DNSVV+LSQ KM++LQLFRGDTVLLKGK+
Sbjct: 5   ADSKG-DDLSTAILKQKNRPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKK 63

Query: 251 RKETVCIVLSDDNCPDEKIRMXXXXXXXXXXXXSDVVSIAPCPSVKYGKRVHILPIDDSV 430
           R+E VCIVLSDD C DEKIRM             DV+SI PCP VKYGKR+H+LPIDD+V
Sbjct: 64  RREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTV 123

Query: 431 EGLTGNLFEVYLKPYFMEAYRPIHRDD 511
           EG+TGNLFEVYLKPYF+EAYRPI + D
Sbjct: 124 EGITGNLFEVYLKPYFLEAYRPIRKGD 150


>UniRef50_A4ICJ9 Cluster: Transitional endoplasmic reticulum ATPase,
           putative; n=2; Leishmania|Rep: Transitional endoplasmic
           reticulum ATPase, putative - Leishmania infantum
          Length = 690

 Score =  163 bits (397), Expect = 2e-39
 Identities = 72/132 (54%), Positives = 95/132 (71%)
 Frame = +2

Query: 119 KDRPNRLIVEEAVSDDNSVVALSQAKMEQLQLFRGDTVLLKGKRRKETVCIVLSDDNCPD 298
           K + N+LIVEE  +DDNSVV+L+  +ME+L +FRGDTVL+KGK+ + TVCI + DD CP 
Sbjct: 11  KVKLNKLIVEEPYNDDNSVVSLNPKRMEELNIFRGDTVLVKGKKHRSTVCIAMEDDECPP 70

Query: 299 EKIRMXXXXXXXXXXXXSDVVSIAPCPSVKYGKRVHILPIDDSVEGLTGNLFEVYLKPYF 478
           EKI+M             D + I PC  V YG RVH+LPIDD+VE LTG+LFE +LKPYF
Sbjct: 71  EKIKMNKVARRNIRIHLGDTIRIVPCKDVPYGNRVHLLPIDDTVENLTGDLFENFLKPYF 130

Query: 479 MEAYRPIHRDDT 514
           +E+YRP+ + D+
Sbjct: 131 LESYRPVKKGDS 142


>UniRef50_Q4Y788 Cluster: Cell division cycle protein 48 homologue,
           putative; n=4; Plasmodium|Rep: Cell division cycle
           protein 48 homologue, putative - Plasmodium chabaudi
          Length = 250

 Score =  151 bits (366), Expect = 9e-36
 Identities = 69/147 (46%), Positives = 99/147 (67%), Gaps = 1/147 (0%)
 Frame = +2

Query: 74  DNKSPDDLSTAILRRKDRPNRLIVEEAVSDDNSVVALSQAKMEQLQLFRGDTVLLKGKRR 253
           D K+  D +   L +K    RLIVEEA +DDNSVVAL+  +ME+L  FRGDT+L+KGK+R
Sbjct: 6   DTKTLGDDNNGKLPKKKNLCRLIVEEATNDDNSVVALNTKRMEELNFFRGDTILIKGKKR 65

Query: 254 KETVCIVLSDDNCPDEKIRMXXXXXXXXXXXXSDVVSIAPCPSVKYGKRVHILPIDDSVE 433
             T+CI+L+D++  + KIR+             D+V +  CP + YGK++ +LPIDD++E
Sbjct: 66  HSTICIILNDNDLDEGKIRINKVARKNLRVCLGDIVYVKACPEIPYGKKIQVLPIDDTIE 125

Query: 434 GLT-GNLFEVYLKPYFMEAYRPIHRDD 511
           GL    LFE++LKPYF E+YRP+ + D
Sbjct: 126 GLAKDTLFEIFLKPYFNESYRPVKKGD 152


>UniRef50_UPI0000E4A84B Cluster: PREDICTED: similar to valosin; n=3;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           valosin - Strongylocentrotus purpuratus
          Length = 596

 Score =  135 bits (326), Expect = 6e-31
 Identities = 78/148 (52%), Positives = 100/148 (67%)
 Frame = +2

Query: 68  MADNKSPDDLSTAILRRKDRPNRLIVEEAVSDDNSVVALSQAKMEQLQLFRGDTVLLKGK 247
           MA+N S DD++TAILR K +PNRL+VEEA++DDNSVV+LSQAKM++LQLFRGDTV+LKGK
Sbjct: 1   MAEN-SGDDIATAILRTKAKPNRLVVEEAINDDNSVVSLSQAKMDELQLFRGDTVMLKGK 59

Query: 248 RRKETVCIVLSDDNCPDEKIRMXXXXXXXXXXXXSDVVSIAPCPSVKYGKRVHILPIDDS 427
           +R++TVCIVLSDD   D+KIR+                       V+   RV    + D 
Sbjct: 60  KRRDTVCIVLSDDTVTDDKIRVNRV--------------------VRSNLRVR---LGDI 96

Query: 428 VEGLTGNLFEVYLKPYFMEAYRPIHRDD 511
           V  L    F+VYL+PYF EAYRP+ + D
Sbjct: 97  VRNL----FDVYLRPYFQEAYRPVRKGD 120


>UniRef50_A0EEE7 Cluster: Chromosome undetermined scaffold_91, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_91,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 772

 Score =  105 bits (251), Expect = 8e-22
 Identities = 55/128 (42%), Positives = 77/128 (60%), Gaps = 1/128 (0%)
 Frame = +2

Query: 131 NRLIVEEAVSDDNSVVALSQAKMEQLQLFRGDTVLLKGKRRKETVCIVLSDDNCPDEKIR 310
           NRL+V E+ +DDNSVV L Q K+ +L+LF+GD VLL+GK  K+TV I +S+     E + 
Sbjct: 17  NRLMVCESTADDNSVVQLCQDKLNELKLFKGDMVLLEGKNNKKTVAIAISNRQ-DKESVH 75

Query: 311 MXXXXXXXXXXXXSDVVSIAPCPSVKYGKRVHILPIDDSVEGLT-GNLFEVYLKPYFMEA 487
           M             D ++I P  S+    +VHILP  DS+ G    NL + YL PYF++A
Sbjct: 76  MNSVIRKNLGIQIGDFITIQPTASLPQLTKVHILPFQDSISGTNEKNLTQNYLIPYFLDA 135

Query: 488 YRPIHRDD 511
           YRP+ + D
Sbjct: 136 YRPVSKGD 143


>UniRef50_Q4YQQ6 Cluster: Cell division cycle ATPase, putative; n=3;
           Plasmodium (Vinckeia)|Rep: Cell division cycle ATPase,
           putative - Plasmodium berghei
          Length = 932

 Score = 69.7 bits (163), Expect = 4e-11
 Identities = 41/131 (31%), Positives = 67/131 (51%), Gaps = 2/131 (1%)
 Frame = +2

Query: 128 PNRLIVEEAVSD-DNSVVALSQAKMEQLQLFRGDTVLLKGKRRKETVCIVLSDDNCPDEK 304
           PN  +VE    + DN  + +S+ KM++L +  G TVLLKGK++KE V IV  D+      
Sbjct: 101 PNYCLVENIDENADNFDIYMSKEKMKELNINDGFTVLLKGKKKKEMVAIVREDNRLNKYS 160

Query: 305 IRMXXXXXXXXXXXXSDVVSIAPCPSVKYGKRVHILPIDDSVEGLTGNLFE-VYLKPYFM 481
           + +            +D++ I P  ++K  K V + P +D+V  +T    E   L  Y  
Sbjct: 161 VSISFSIKRNLRLMHNDIIKIYPLSNIKNIKNVILSPFNDTVNNITKQEIEKEILNTYLK 220

Query: 482 EAYRPIHRDDT 514
            +Y+P+  D+T
Sbjct: 221 NSYKPLSVDNT 231


>UniRef50_A5KAB5 Cluster: Cell division cycle ATPase, putative; n=1;
           Plasmodium vivax|Rep: Cell division cycle ATPase,
           putative - Plasmodium vivax
          Length = 1089

 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 40/126 (31%), Positives = 62/126 (49%), Gaps = 2/126 (1%)
 Frame = +2

Query: 128 PNRLIVEEAVSD-DNSVVALSQAKMEQLQLFRGDTVLLKGKRRKETVCIVLSDDNCPDEK 304
           P+  +VE      DN  + LS+AKME+L L  G TVLLKGK++KE + I   D       
Sbjct: 270 PSYCLVENVDEQIDNCEIYLSKAKMEELNLSEGFTVLLKGKKKKEMLAIAKLDRRLQKHF 329

Query: 305 IRMXXXXXXXXXXXXSDVVSIAPCPSVKYGKRVHILPIDDSVEGLT-GNLFEVYLKPYFM 481
           + +            +D++ I P   V   + V + P  D+V GL+   L +  L+PY  
Sbjct: 330 VVISFAMKKNLRLMHNDIIKIFPLMKVHPLRTVVLSPFSDTVGGLSKAELEQEVLRPYLK 389

Query: 482 EAYRPI 499
             ++P+
Sbjct: 390 GTFKPL 395


>UniRef50_Q7QWL6 Cluster: GLP_762_31096_33708; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_762_31096_33708 - Giardia lamblia
           ATCC 50803
          Length = 870

 Score = 61.3 bits (142), Expect = 1e-08
 Identities = 33/103 (32%), Positives = 52/103 (50%)
 Frame = +2

Query: 131 NRLIVEEAVSDDNSVVALSQAKMEQLQLFRGDTVLLKGKRRKETVCIVLSDDNCPDEKIR 310
           NR IV +    D+S + LS  K+  L LF+GD V LKG+  K T  +V S ++     + 
Sbjct: 12  NRFIVNDNPGGDDSQIILSSEKVNVLDLFQGDYVRLKGRFGKTTHAMVQSREDVDKIVVL 71

Query: 311 MXXXXXXXXXXXXSDVVSIAPCPSVKYGKRVHILPIDDSVEGL 439
           M             D+V + P  ++ Y KR+ ++P +  +EGL
Sbjct: 72  MNKTMRANLGVNLGDIVILYPAQNLPYHKRIKVIPFEQDLEGL 114


>UniRef50_A7AVE1 Cluster: Cell division cycle protein ATPase,
           putative; n=1; Babesia bovis|Rep: Cell division cycle
           protein ATPase, putative - Babesia bovis
          Length = 922

 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 2/103 (1%)
 Frame = +2

Query: 128 PNRLIVEEAVSDDNSVVALSQAK--MEQLQLFRGDTVLLKGKRRKETVCIVLSDDNCPDE 301
           PN L V   V D NS + +   K    +L +  G+ V ++GK+R +TVC+V  D N  D 
Sbjct: 133 PN-LFVLSGVFDGNSSIEIRMGKEPANKLGVAEGNLVRVRGKKRCDTVCVVGIDPNITDN 191

Query: 302 KIRMXXXXXXXXXXXXSDVVSIAPCPSVKYGKRVHILPIDDSV 430
           ++ +             DV+SI     +   K V ++P +DSV
Sbjct: 192 QVLIHSDTRRNLKLRTGDVMSIDLISDIPPAKLVKLMPFEDSV 234


>UniRef50_Q4MZM6 Cluster: Cell division cycle protein 48, putative;
           n=1; Theileria parva|Rep: Cell division cycle protein
           48, putative - Theileria parva
          Length = 954

 Score = 48.8 bits (111), Expect = 7e-05
 Identities = 29/97 (29%), Positives = 46/97 (47%)
 Frame = +2

Query: 161 DDNSVVALSQAKMEQLQLFRGDTVLLKGKRRKETVCIVLSDDNCPDEKIRMXXXXXXXXX 340
           + N  V + +A+  +L +  GD + +KG+RRK TVC V   ++    ++           
Sbjct: 154 NSNVNVRIGKAQANKLSVMPGDLLKVKGRRRKVTVCGVDVTESITKNEVSFHEDLRRNLR 213

Query: 341 XXXSDVVSIAPCPSVKYGKRVHILPIDDSVEGLTGNL 451
               DVV +    +V   K VHILP  D++E L   L
Sbjct: 214 LRLGDVVFMEKINTVPEAKFVHILPFKDTIEPLIKQL 250


>UniRef50_Q1JSD1 Cluster: Transitional endoplasmic reticulum ATPase;
           n=1; Toxoplasma gondii|Rep: Transitional endoplasmic
           reticulum ATPase - Toxoplasma gondii
          Length = 792

 Score = 48.8 bits (111), Expect = 7e-05
 Identities = 23/78 (29%), Positives = 39/78 (50%)
 Frame = +2

Query: 197 MEQLQLFRGDTVLLKGKRRKETVCIVLSDDNCPDEKIRMXXXXXXXXXXXXSDVVSIAPC 376
           M  LQ+ RGD VLL G+R++ETV I + D +     + +             D + + P 
Sbjct: 1   MAALQVQRGDVVLLSGRRKRETVAIAMPDRSLEARHVVLHAHALKNIKLHAQDAIKVTPQ 60

Query: 377 PSVKYGKRVHILPIDDSV 430
             + + +RV +LP  D++
Sbjct: 61  RLLPHARRVFVLPFSDTL 78


>UniRef50_Q4UBT9 Cluster: Cell divison cycle CDC48 homologue,
           putative or transitional endoplasmic reticulum ATPase,
           putative; n=1; Theileria annulata|Rep: Cell divison
           cycle CDC48 homologue, putative or transitional
           endoplasmic reticulum ATPase, putative - Theileria
           annulata
          Length = 905

 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 27/97 (27%), Positives = 45/97 (46%)
 Frame = +2

Query: 161 DDNSVVALSQAKMEQLQLFRGDTVLLKGKRRKETVCIVLSDDNCPDEKIRMXXXXXXXXX 340
           + N  V + + +  +L L  GD V ++G+RRK TVC V   ++    ++           
Sbjct: 129 NSNVNVKIGKEQANKLNLMTGDFVKVRGRRRKVTVCGVDVTESITKNEVSFHEDLRRNLR 188

Query: 341 XXXSDVVSIAPCPSVKYGKRVHILPIDDSVEGLTGNL 451
               D+V +    ++   K VHILP  D++E L   L
Sbjct: 189 LRLGDIVFMDKINTIPEAKIVHILPFKDTIEPLIKQL 225


>UniRef50_A2FWK7 Cluster: ATPase, AAA family protein; n=1;
           Trichomonas vaginalis G3|Rep: ATPase, AAA family protein
           - Trichomonas vaginalis G3
          Length = 2005

 Score = 35.1 bits (77), Expect = 0.96
 Identities = 24/105 (22%), Positives = 47/105 (44%), Gaps = 1/105 (0%)
 Frame = +2

Query: 149 EAVSDDNSVVA-LSQAKMEQLQLFRGDTVLLKGKRRKETVCIVLSDDNCPDEKIRMXXXX 325
           + V D N + A +S   M  L +  G  V ++ ++  +T+  +   D  PD  IR+    
Sbjct: 9   DKVDDFNDLNAYISNKAMNALGISDGSVVSVRNQQNSQTLVAIQGCD-MPDNVIRLSRCH 67

Query: 326 XXXXXXXXSDVVSIAPCPSVKYGKRVHILPIDDSVEGLTGNLFEV 460
                    + V I+     +  + V + PI D++ G++GN  ++
Sbjct: 68  RINIGSFLGETVKISKPIKSQKAEIVLVAPIADTINGISGNFCDL 112


>UniRef50_UPI0000499E59 Cluster: hypothetical protein 73.t00008;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
           protein 73.t00008 - Entamoeba histolytica HM-1:IMSS
          Length = 586

 Score = 33.5 bits (73), Expect = 2.9
 Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 5/86 (5%)
 Frame = +2

Query: 68  MADNKSPDDLSTAILRRKDRPNRLIVEEAVSDDNSVVALSQAKMEQLQLFR-----GDTV 232
           ++D+ S DD+ T + +   +   L   ++  DD+   AL++ + E+ + F       D  
Sbjct: 130 ISDSDSDDDVKTDVKKTTTKKEELSDSDSDDDDDIAAALAKKRAERAKKFAISDSDSDDD 189

Query: 233 LLKGKRRKETVCIVLSDDNCPDEKIR 310
            +K   +K T  I LSD +  D+ I+
Sbjct: 190 DIKPAAKKTTKKISLSDSDSDDDDIK 215


>UniRef50_Q7QTA1 Cluster: GLP_15_26945_31573; n=3; root|Rep:
            GLP_15_26945_31573 - Giardia lamblia ATCC 50803
          Length = 1542

 Score = 33.5 bits (73), Expect = 2.9
 Identities = 22/87 (25%), Positives = 34/87 (39%), Gaps = 8/87 (9%)
 Frame = -2

Query: 434  PQLN-HQLAVCGLVFHISLKDTELWIPHQKDAHEGCFSRHGSSEFSH-------QGNYHL 279
            P +N + +++ G  +  S K+    +P     HEG FS     E+ H        G Y  
Sbjct: 1125 PHMNPYTISISGTRYEFSTKNDTYTVPFPLTVHEGRFSVPTKIEYFHPDRPTCKDGEYAW 1184

Query: 278  RARCKRFPCGVCL*ARLCHHGRVEVAP 198
            R +   F C +C     C  G +   P
Sbjct: 1185 RLQTGAFTCMICPTGYFCSEGVMNPCP 1211


>UniRef50_Q28VJ3 Cluster: Putative uncharacterized protein; n=1;
           Jannaschia sp. CCS1|Rep: Putative uncharacterized
           protein - Jannaschia sp. (strain CCS1)
          Length = 348

 Score = 32.7 bits (71), Expect = 5.1
 Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 2/69 (2%)
 Frame = +2

Query: 83  SPDDLST--AILRRKDRPNRLIVEEAVSDDNSVVALSQAKMEQLQLFRGDTVLLKGKRRK 256
           S  DL+T  A++R + +P R+     + DD + + +    ME   L  GD + L G++  
Sbjct: 259 SAADLATGRAVVRDRTKPMRIFYH-LMLDDPACLLVENCPMETAHL--GDVMALGGRQIS 315

Query: 257 ETVCIVLSD 283
           +  C VLSD
Sbjct: 316 QAACPVLSD 324


>UniRef50_Q4E0K4 Cluster: Ubiquitin hydrolase, putative; n=3;
           Trypanosoma cruzi|Rep: Ubiquitin hydrolase, putative -
           Trypanosoma cruzi
          Length = 1135

 Score = 31.9 bits (69), Expect = 8.9
 Identities = 9/17 (52%), Positives = 13/17 (76%)
 Frame = -2

Query: 227 CHHGRVEVAPFWPVKVP 177
           CHH R +++PFW + VP
Sbjct: 752 CHHTRTQLSPFWDISVP 768


>UniRef50_A6R127 Cluster: Putative uncharacterized protein; n=1;
           Ajellomyces capsulatus NAm1|Rep: Putative
           uncharacterized protein - Ajellomyces capsulatus NAm1
          Length = 885

 Score = 31.9 bits (69), Expect = 8.9
 Identities = 17/45 (37%), Positives = 28/45 (62%)
 Frame = +2

Query: 128 PNRLIVEEAVSDDNSVVALSQAKMEQLQLFRGDTVLLKGKRRKET 262
           P R    +A SD+ S+V + ++ +  +++ RGDT L KGKR+  T
Sbjct: 407 PERCGDVDATSDERSMVVVEESYLP-VEIDRGDTRLGKGKRKAST 450


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 520,781,231
Number of Sequences: 1657284
Number of extensions: 9827539
Number of successful extensions: 24812
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 24164
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 24806
length of database: 575,637,011
effective HSP length: 95
effective length of database: 418,195,031
effective search space used: 31782822356
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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