Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= epV30559
(516 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 96 6e-20
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 96 6e-20
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 96 6e-20
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 91 3e-18
U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 66 7e-11
D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 66 7e-11
BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family... 66 7e-11
BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 66 7e-11
BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 66 7e-11
BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 66 7e-11
AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 66 7e-11
AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 66 7e-11
AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 66 7e-11
AF221943-1|AAF86378.1| 175|Homo sapiens leukotriene B4 omega hy... 66 7e-11
AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 66 7e-11
AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 66 7e-11
AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 66 7e-11
AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 66 7e-11
AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 66 9e-11
AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 65 2e-10
AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. 65 2e-10
BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family... 64 4e-10
BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family... 64 4e-10
BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family... 64 4e-10
D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV prot... 63 5e-10
D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV prot... 63 5e-10
AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family... 63 5e-10
AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hy... 63 5e-10
AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hy... 63 5e-10
BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 63 6e-10
AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 63 6e-10
X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for ... 62 1e-09
DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family... 62 1e-09
BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family... 62 1e-09
AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P4... 62 1e-09
AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. 62 1e-09
AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. 62 1e-09
AY064484-1|AAL57719.1| 295|Homo sapiens truncated cytochrome P4... 62 1e-09
AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family... 62 1e-09
AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family... 62 1e-09
AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family... 62 1e-09
AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family... 62 1e-09
AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens ... 62 1e-09
AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. 62 1e-09
J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cyto... 60 5e-09
S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxyl... 60 6e-09
S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxyl... 60 6e-09
L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. 60 6e-09
D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxy... 60 6e-09
D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxyl... 60 6e-09
BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. 60 6e-09
BC022851-1|AAH22851.1| 215|Homo sapiens CYP4A11 protein protein. 60 6e-09
AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family... 60 6e-09
AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family... 60 6e-09
AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family... 60 6e-09
AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfam... 60 6e-09
AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 57 4e-08
BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein. 56 6e-08
AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K p... 56 6e-08
BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein. 53 5e-07
AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 52 9e-07
AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, famil... 52 9e-07
AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family... 52 9e-07
BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 52 1e-06
AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 52 1e-06
AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 52 1e-06
AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 52 1e-06
AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 52 1e-06
AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 51 2e-06
AY696295-1|AAU10524.1| 292|Homo sapiens cytochrome P450 protein. 51 3e-06
M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein. 50 5e-06
BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein. 50 5e-06
AK097373-1|BAC05026.1| 340|Homo sapiens protein ( Homo sapiens ... 50 5e-06
AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. 50 6e-06
AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. 50 6e-06
AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family... 50 6e-06
AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family... 50 6e-06
AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens ... 48 2e-05
AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 48 2e-05
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 47 3e-05
J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 47 3e-05
J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 47 3e-05
DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 47 3e-05
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 47 3e-05
DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 47 3e-05
BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 47 3e-05
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 47 3e-05
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 47 3e-05
AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 47 3e-05
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 47 3e-05
AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 47 3e-05
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 47 3e-05
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 47 5e-05
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 47 5e-05
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 47 5e-05
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 47 5e-05
EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1 var... 47 5e-05
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 47 5e-05
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 47 5e-05
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 47 5e-05
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 47 5e-05
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 47 5e-05
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 47 5e-05
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 47 5e-05
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 47 5e-05
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 47 5e-05
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 47 5e-05
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 47 5e-05
U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 46 6e-05
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 46 6e-05
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 46 6e-05
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 46 6e-05
BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein. 46 6e-05
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 46 6e-05
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 46 6e-05
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 46 6e-05
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 46 6e-05
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 46 8e-05
BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 46 1e-04
U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 45 1e-04
S63426-1|ABB76283.1| 214|Homo sapiens (S)-mephenytoin hydroxyla... 44 2e-04
M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 44 2e-04
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 44 3e-04
AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1 pro... 44 3e-04
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 44 4e-04
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 44 4e-04
L16880-1|AAD13466.1| 273|Homo sapiens cytochrome P-450 2C protein. 44 4e-04
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 44 4e-04
EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1 var... 44 4e-04
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 44 4e-04
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 44 4e-04
BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein. 44 4e-04
BC070317-1|AAH70317.1| 162|Homo sapiens CYP2C9 protein protein. 44 4e-04
BC020754-1|AAH20754.1| 162|Homo sapiens CYP2C9 protein protein. 44 4e-04
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 44 4e-04
AY513607-1|AAR90938.1| 100|Homo sapiens truncated cytochrome P4... 44 4e-04
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 44 4e-04
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 44 4e-04
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 44 4e-04
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 43 6e-04
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 43 6e-04
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 43 6e-04
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 43 6e-04
M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrom... 43 7e-04
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 43 7e-04
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 43 7e-04
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 42 0.001
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 42 0.001
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 42 0.001
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 42 0.001
AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P4... 42 0.002
AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family... 42 0.002
AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family... 42 0.002
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 42 0.002
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 41 0.002
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 41 0.002
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 41 0.002
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 41 0.002
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 41 0.002
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 41 0.002
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 41 0.002
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 41 0.002
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 41 0.002
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 41 0.002
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 41 0.003
L39098-1|AAL31347.1| 160|Homo sapiens S-mephenytoin 4-hydroxyla... 41 0.003
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 41 0.003
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 41 0.003
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 41 0.003
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 41 0.003
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 41 0.003
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 41 0.003
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 41 0.003
AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family... 40 0.004
AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family... 40 0.004
M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 39 0.009
BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family... 39 0.012
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 39 0.012
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 39 0.012
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 39 0.012
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 39 0.012
AF280111-1|AAG33012.1| 250|Homo sapiens cytochrome P450 subfami... 39 0.012
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 39 0.012
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 39 0.012
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 39 0.012
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 39 0.012
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 39 0.012
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 38 0.021
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 38 0.021
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 38 0.021
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 38 0.021
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 37 0.036
DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P4... 37 0.036
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 37 0.036
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 37 0.036
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 37 0.048
AF280107-1|AAG32291.1| 106|Homo sapiens cytochrome P450 polypep... 35 0.19
BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family... 33 0.45
BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family... 33 0.45
AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1 pro... 33 0.45
X54807-1|CAA38578.1| 56|Homo sapiens unspecific monooxygenase ... 33 0.59
U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 33 0.59
BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 33 0.59
AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 33 0.59
AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 33 0.59
AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450 epoxyge... 33 0.59
AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 33 0.59
BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein. 33 0.78
AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein. 33 0.78
X56452-1|CAA39833.1| 56|Homo sapiens unspecific monooxygenase ... 32 1.4
BC004367-1|AAH04367.1| 313|Homo sapiens potassium channel, subf... 31 1.8
AK222545-1|BAD96265.1| 313|Homo sapiens potassium channel, subf... 31 1.8
AJ297404-1|CAC15489.1| 313|Homo sapiens potassium channel, subf... 31 1.8
AF281303-1|AAG10507.1| 179|Homo sapiens 2P domain K+ channel TW... 31 1.8
AF281302-1|AAG10506.1| 313|Homo sapiens 2P domain K+ channel TW... 31 1.8
AF134149-1|AAD22980.1| 313|Homo sapiens 2-pore K+ channel subun... 31 1.8
AF117708-1|AAD24000.1| 313|Homo sapiens tandem pore domain pota... 31 1.8
DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6 pro... 31 2.4
AF280113-1|AAG33014.1| 74|Homo sapiens cytochrome P450 subfami... 31 2.4
AF280112-1|AAG33013.1| 126|Homo sapiens cytochrome P450 subfami... 31 2.4
AF183185-1|AAG12991.1| 1997|Homo sapiens brain otoferlin long is... 31 3.2
AK024290-1|BAB14875.1| 590|Homo sapiens protein ( Homo sapiens ... 30 4.2
AF280107-4|AAG32288.1| 106|Homo sapiens cytochrome P450 polypep... 30 4.2
AB040956-1|BAA96047.1| 687|Homo sapiens KIAA1523 protein protein. 30 4.2
AF081569-1|AAD25924.1| 52|Homo sapiens cytochrome P450 protein. 29 9.7
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 96.3 bits (229), Expect = 6e-20
Identities = 52/136 (38%), Positives = 80/136 (58%), Gaps = 3/136 (2%)
Frame = +1
Query: 118 LLGLTTAIWILYRWQQNSHMHKLAELIPGPA-PIPIFGNALTLMRKDPHELVNLALGYAQ 294
L G + + +L R + + IP A P+ G+AL LM+ D E + Y +
Sbjct: 24 LAGASLVLSLLQRVASYARKWQQMRPIPTVARAYPLVGHAL-LMKPDGREFFQQIIEYTE 82
Query: 295 TFGNV--VRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPK 468
+ ++ +++W+G +V L +A+++E+IL S IDK++ YKF +PWLG GLL S+G K
Sbjct: 83 EYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNK 142
Query: 469 WRSHRKMIAPTFHINI 516
WRS RKM+ PTFH I
Sbjct: 143 WRSRRKMLTPTFHFTI 158
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 96.3 bits (229), Expect = 6e-20
Identities = 52/136 (38%), Positives = 80/136 (58%), Gaps = 3/136 (2%)
Frame = +1
Query: 118 LLGLTTAIWILYRWQQNSHMHKLAELIPGPA-PIPIFGNALTLMRKDPHELVNLALGYAQ 294
L G + + +L R + + IP A P+ G+AL LM+ D E + Y +
Sbjct: 24 LAGASLVLSLLQRVASYARKWQQMRPIPTVARAYPLVGHAL-LMKPDGREFFQQIIEYTE 82
Query: 295 TFGNV--VRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPK 468
+ ++ +++W+G +V L +A+++E+IL S IDK++ YKF +PWLG GLL S+G K
Sbjct: 83 EYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNK 142
Query: 469 WRSHRKMIAPTFHINI 516
WRS RKM+ PTFH I
Sbjct: 143 WRSRRKMLTPTFHFTI 158
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 96.3 bits (229), Expect = 6e-20
Identities = 52/136 (38%), Positives = 80/136 (58%), Gaps = 3/136 (2%)
Frame = +1
Query: 118 LLGLTTAIWILYRWQQNSHMHKLAELIPGPA-PIPIFGNALTLMRKDPHELVNLALGYAQ 294
L G + + +L R + + IP A P+ G+AL LM+ D E + Y +
Sbjct: 24 LAGASLVLSLLQRVASYARKWQQMRPIPTVARAYPLVGHAL-LMKPDGREFFQQIIEYTE 82
Query: 295 TFGNV--VRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPK 468
+ ++ +++W+G +V L +A+++E+IL S IDK++ YKF +PWLG GLL S+G K
Sbjct: 83 EYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNK 142
Query: 469 WRSHRKMIAPTFHINI 516
WRS RKM+ PTFH I
Sbjct: 143 WRSRRKMLTPTFHFTI 158
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 90.6 bits (215), Expect = 3e-18
Identities = 41/94 (43%), Positives = 62/94 (65%), Gaps = 2/94 (2%)
Frame = +1
Query: 241 LMRKDPHELVNLALGYAQTFGNV--VRVWLGSKLIVFLADADDIEIILNSHVHIDKATEY 414
LM+ D E + Y + + ++ +++W+G +V L +A+++E+IL S IDK++ Y
Sbjct: 43 LMKPDGREFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMY 102
Query: 415 KFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINI 516
KF +PWLG GLL S+G KWRS RKM+ PTFH I
Sbjct: 103 KFLEPWLGLGLLTSTGNKWRSRRKMLTPTFHFTI 136
>U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein.
Length = 520
Score = 66.1 bits (154), Expect = 7e-11
Identities = 34/87 (39%), Positives = 48/87 (55%), Gaps = 3/87 (3%)
Frame = +1
Query: 265 LVNLALGYAQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHIDKATE--YKFFKPWL 435
L L Y Q F +VW+G ++ L D I ++N+ I + Y F +PWL
Sbjct: 77 LTQLVATYPQGF----KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWL 132
Query: 436 GEGLLISSGPKWRSHRKMIAPTFHINI 516
G+GLL+S+G KW HR+M+ P FH NI
Sbjct: 133 GDGLLLSAGDKWSRHRRMLTPAFHFNI 159
>D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 66.1 bits (154), Expect = 7e-11
Identities = 34/87 (39%), Positives = 48/87 (55%), Gaps = 3/87 (3%)
Frame = +1
Query: 265 LVNLALGYAQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHIDKATE--YKFFKPWL 435
L L Y Q F +VW+G ++ L D I ++N+ I + Y F +PWL
Sbjct: 77 LTQLVATYPQGF----KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWL 132
Query: 436 GEGLLISSGPKWRSHRKMIAPTFHINI 516
G+GLL+S+G KW HR+M+ P FH NI
Sbjct: 133 GDGLLLSAGDKWSRHRRMLTPAFHFNI 159
>BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 66.1 bits (154), Expect = 7e-11
Identities = 34/87 (39%), Positives = 48/87 (55%), Gaps = 3/87 (3%)
Frame = +1
Query: 265 LVNLALGYAQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHIDKATE--YKFFKPWL 435
L L Y Q F +VW+G ++ L D I ++N+ I + Y F +PWL
Sbjct: 77 LTQLVATYPQGF----KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWL 132
Query: 436 GEGLLISSGPKWRSHRKMIAPTFHINI 516
G+GLL+S+G KW HR+M+ P FH NI
Sbjct: 133 GDGLLLSAGDKWSRHRRMLTPAFHFNI 159
>BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 66.1 bits (154), Expect = 7e-11
Identities = 34/87 (39%), Positives = 48/87 (55%), Gaps = 3/87 (3%)
Frame = +1
Query: 265 LVNLALGYAQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHIDKATE--YKFFKPWL 435
L L Y Q F +VW+G ++ L D I ++N+ I + Y F +PWL
Sbjct: 77 LTQLVATYPQGF----KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWL 132
Query: 436 GEGLLISSGPKWRSHRKMIAPTFHINI 516
G+GLL+S+G KW HR+M+ P FH NI
Sbjct: 133 GDGLLLSAGDKWSRHRRMLTPAFHFNI 159
>BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 66.1 bits (154), Expect = 7e-11
Identities = 34/87 (39%), Positives = 48/87 (55%), Gaps = 3/87 (3%)
Frame = +1
Query: 265 LVNLALGYAQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHIDKATE--YKFFKPWL 435
L L Y Q F +VW+G ++ L D I ++N+ I + Y F +PWL
Sbjct: 77 LTQLVATYPQGF----KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWL 132
Query: 436 GEGLLISSGPKWRSHRKMIAPTFHINI 516
G+GLL+S+G KW HR+M+ P FH NI
Sbjct: 133 GDGLLLSAGDKWSRHRRMLTPAFHFNI 159
>BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 12 protein.
Length = 524
Score = 66.1 bits (154), Expect = 7e-11
Identities = 32/77 (41%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
Frame = +1
Query: 295 TFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLLISSGP 465
T+ VWLG + + L D I I N+ I +F KPWLGEG+L+S G
Sbjct: 83 TYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGD 142
Query: 466 KWRSHRKMIAPTFHINI 516
KW HR+M+ P FH NI
Sbjct: 143 KWSRHRRMLTPAFHFNI 159
>AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein.
Length = 524
Score = 66.1 bits (154), Expect = 7e-11
Identities = 32/77 (41%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
Frame = +1
Query: 295 TFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLLISSGP 465
T+ VWLG + + L D I I N+ I +F KPWLGEG+L+S G
Sbjct: 83 TYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGD 142
Query: 466 KWRSHRKMIAPTFHINI 516
KW HR+M+ P FH NI
Sbjct: 143 KWSRHRRMLTPAFHFNI 159
>AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform
4F12 protein.
Length = 524
Score = 66.1 bits (154), Expect = 7e-11
Identities = 32/77 (41%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
Frame = +1
Query: 295 TFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLLISSGP 465
T+ VWLG + + L D I I N+ I +F KPWLGEG+L+S G
Sbjct: 83 TYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGD 142
Query: 466 KWRSHRKMIAPTFHINI 516
KW HR+M+ P FH NI
Sbjct: 143 KWSRHRRMLTPAFHFNI 159
>AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfamily
IVF, polypeptide 2 protein.
Length = 520
Score = 66.1 bits (154), Expect = 7e-11
Identities = 34/87 (39%), Positives = 48/87 (55%), Gaps = 3/87 (3%)
Frame = +1
Query: 265 LVNLALGYAQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHIDKATE--YKFFKPWL 435
L L Y Q F +VW+G ++ L D I ++N+ I + Y F +PWL
Sbjct: 77 LTQLVATYPQGF----KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWL 132
Query: 436 GEGLLISSGPKWRSHRKMIAPTFHINI 516
G+GLL+S+G KW HR+M+ P FH NI
Sbjct: 133 GDGLLLSAGDKWSRHRRMLTPAFHFNI 159
>AF221943-1|AAF86378.1| 175|Homo sapiens leukotriene B4 omega
hydroxylase protein.
Length = 175
Score = 66.1 bits (154), Expect = 7e-11
Identities = 34/87 (39%), Positives = 48/87 (55%), Gaps = 3/87 (3%)
Frame = +1
Query: 265 LVNLALGYAQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHIDKATE--YKFFKPWL 435
L L Y Q F +VW+G ++ L D I ++N+ I + Y F +PWL
Sbjct: 77 LTQLVATYPQGF----KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWL 132
Query: 436 GEGLLISSGPKWRSHRKMIAPTFHINI 516
G+GLL+S+G KW HR+M+ P FH NI
Sbjct: 133 GDGLLLSAGDKWSRHRRMLTPAFHFNI 159
>AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein.
Length = 520
Score = 66.1 bits (154), Expect = 7e-11
Identities = 34/87 (39%), Positives = 48/87 (55%), Gaps = 3/87 (3%)
Frame = +1
Query: 265 LVNLALGYAQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHIDKATE--YKFFKPWL 435
L L Y Q F +VW+G ++ L D I ++N+ I + Y F +PWL
Sbjct: 77 LTQLVATYPQGF----KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWL 132
Query: 436 GEGLLISSGPKWRSHRKMIAPTFHINI 516
G+GLL+S+G KW HR+M+ P FH NI
Sbjct: 133 GDGLLLSAGDKWSRHRRMLTPAFHFNI 159
>AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 66.1 bits (154), Expect = 7e-11
Identities = 32/77 (41%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
Frame = +1
Query: 295 TFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLLISSGP 465
T+ VWLG + + L D I I N+ I +F KPWLGEG+L+S G
Sbjct: 83 TYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGD 142
Query: 466 KWRSHRKMIAPTFHINI 516
KW HR+M+ P FH NI
Sbjct: 143 KWSRHRRMLTPAFHFNI 159
>AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 66.1 bits (154), Expect = 7e-11
Identities = 32/77 (41%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
Frame = +1
Query: 295 TFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLLISSGP 465
T+ VWLG + + L D I I N+ I +F KPWLGEG+L+S G
Sbjct: 83 TYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGD 142
Query: 466 KWRSHRKMIAPTFHINI 516
KW HR+M+ P FH NI
Sbjct: 143 KWSRHRRMLTPAFHFNI 159
>AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 66.1 bits (154), Expect = 7e-11
Identities = 34/87 (39%), Positives = 48/87 (55%), Gaps = 3/87 (3%)
Frame = +1
Query: 265 LVNLALGYAQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHIDKATE--YKFFKPWL 435
L L Y Q F +VW+G ++ L D I ++N+ I + Y F +PWL
Sbjct: 77 LTQLVATYPQGF----KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWL 132
Query: 436 GEGLLISSGPKWRSHRKMIAPTFHINI 516
G+GLL+S+G KW HR+M+ P FH NI
Sbjct: 133 GDGLLLSAGDKWSRHRRMLTPAFHFNI 159
>AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein.
Length = 458
Score = 65.7 bits (153), Expect = 9e-11
Identities = 31/77 (40%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
Frame = +1
Query: 295 TFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLLISSGP 465
T+ +WLG + + L D I I N+ I +F KPWLGEG+L+S G
Sbjct: 17 TYSQGFTIWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGD 76
Query: 466 KWRSHRKMIAPTFHINI 516
KW HR+M+ P FH NI
Sbjct: 77 KWSRHRRMLTPAFHFNI 93
>AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein.
Length = 520
Score = 64.9 bits (151), Expect = 2e-10
Identities = 39/87 (44%), Positives = 49/87 (56%), Gaps = 3/87 (3%)
Frame = +1
Query: 265 LVNLALGYAQTFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHI-DK-ATEYKFFKPWL 435
L L Y Q F VR WLG I+ L D + ++N+ I DK YK KPWL
Sbjct: 77 LTQLVATYPQGF---VR-WLGPITPIINLCHPDIVRSVINTSDAITDKDIVFYKTLKPWL 132
Query: 436 GEGLLISSGPKWRSHRKMIAPTFHINI 516
G+GLL+S G KWR HR+++ P FH NI
Sbjct: 133 GDGLLLSVGDKWRHHRRLLTPAFHFNI 159
>AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein.
Length = 520
Score = 64.9 bits (151), Expect = 2e-10
Identities = 35/88 (39%), Positives = 48/88 (54%), Gaps = 4/88 (4%)
Frame = +1
Query: 265 LVNLALGYAQTFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHI---DKATEYKFFKPW 432
L L Y Q F +VW+G ++ + I ++N+ I DK Y F KPW
Sbjct: 77 LTQLVATYPQGF----KVWMGPIFPVIRFCHPNIIRSVINASAAIVPKDKVF-YSFLKPW 131
Query: 433 LGEGLLISSGPKWRSHRKMIAPTFHINI 516
LG+GLL+S+G KW HR+M+ P FH NI
Sbjct: 132 LGDGLLLSAGEKWSRHRRMLTPAFHFNI 159
>BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 63.7 bits (148), Expect = 4e-10
Identities = 30/74 (40%), Positives = 45/74 (60%), Gaps = 3/74 (4%)
Frame = +1
Query: 304 NVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATE--YKFFKPWLGEGLLISSGPKWR 474
+V+ VW+G L ++ L D I+ +L + I + Y F KPWLG+GLL+S G KW
Sbjct: 94 HVLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGLLLSKGDKWS 153
Query: 475 SHRKMIAPTFHINI 516
HR+++ P FH +I
Sbjct: 154 RHRRLLTPAFHFDI 167
>BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 63.7 bits (148), Expect = 4e-10
Identities = 30/74 (40%), Positives = 45/74 (60%), Gaps = 3/74 (4%)
Frame = +1
Query: 304 NVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATE--YKFFKPWLGEGLLISSGPKWR 474
+V+ VW+G L ++ L D I+ +L + I + Y F KPWLG+GLL+S G KW
Sbjct: 94 HVLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGLLLSKGDKWS 153
Query: 475 SHRKMIAPTFHINI 516
HR+++ P FH +I
Sbjct: 154 RHRRLLTPAFHFDI 167
>BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 63.7 bits (148), Expect = 4e-10
Identities = 30/74 (40%), Positives = 45/74 (60%), Gaps = 3/74 (4%)
Frame = +1
Query: 304 NVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATE--YKFFKPWLGEGLLISSGPKWR 474
+V+ VW+G L ++ L D I+ +L + I + Y F KPWLG+GLL+S G KW
Sbjct: 94 HVLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGLLLSKGDKWS 153
Query: 475 SHRKMIAPTFHINI 516
HR+++ P FH +I
Sbjct: 154 RHRRLLTPAFHFDI 167
>D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV
protein.
Length = 389
Score = 63.3 bits (147), Expect = 5e-10
Identities = 35/80 (43%), Positives = 47/80 (58%), Gaps = 4/80 (5%)
Frame = +1
Query: 289 AQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHI---DKATEYKFFKPWLGEGLLIS 456
A TFG++ W+G IV + I+ +L + I DK Y F KPWLG+GLL+S
Sbjct: 81 ACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVF-YSFLKPWLGDGLLLS 139
Query: 457 SGPKWRSHRKMIAPTFHINI 516
+G KW HR+M+ P FH NI
Sbjct: 140 AGEKWSRHRRMLTPAFHFNI 159
>D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV
protein.
Length = 520
Score = 63.3 bits (147), Expect = 5e-10
Identities = 35/80 (43%), Positives = 47/80 (58%), Gaps = 4/80 (5%)
Frame = +1
Query: 289 AQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHI---DKATEYKFFKPWLGEGLLIS 456
A TFG++ W+G IV + I+ +L + I DK Y F KPWLG+GLL+S
Sbjct: 81 ACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVF-YSFLKPWLGDGLLLS 139
Query: 457 SGPKWRSHRKMIAPTFHINI 516
+G KW HR+M+ P FH NI
Sbjct: 140 AGEKWSRHRRMLTPAFHFNI 159
>AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 3 protein.
Length = 520
Score = 63.3 bits (147), Expect = 5e-10
Identities = 35/80 (43%), Positives = 47/80 (58%), Gaps = 4/80 (5%)
Frame = +1
Query: 289 AQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHI---DKATEYKFFKPWLGEGLLIS 456
A TFG++ W+G IV + I+ +L + I DK Y F KPWLG+GLL+S
Sbjct: 81 ACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVF-YSFLKPWLGDGLLLS 139
Query: 457 SGPKWRSHRKMIAPTFHINI 516
+G KW HR+M+ P FH NI
Sbjct: 140 AGEKWSRHRRMLTPAFHFNI 159
>AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 63.3 bits (147), Expect = 5e-10
Identities = 35/80 (43%), Positives = 47/80 (58%), Gaps = 4/80 (5%)
Frame = +1
Query: 289 AQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHI---DKATEYKFFKPWLGEGLLIS 456
A TFG++ W+G IV + I+ +L + I DK Y F KPWLG+GLL+S
Sbjct: 81 ACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVF-YSFLKPWLGDGLLLS 139
Query: 457 SGPKWRSHRKMIAPTFHINI 516
+G KW HR+M+ P FH NI
Sbjct: 140 AGEKWSRHRRMLTPAFHFNI 159
>AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 63.3 bits (147), Expect = 5e-10
Identities = 35/80 (43%), Positives = 47/80 (58%), Gaps = 4/80 (5%)
Frame = +1
Query: 289 AQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHI---DKATEYKFFKPWLGEGLLIS 456
A TFG++ W+G IV + I+ +L + I DK Y F KPWLG+GLL+S
Sbjct: 81 ACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVF-YSFLKPWLGDGLLLS 139
Query: 457 SGPKWRSHRKMIAPTFHINI 516
+G KW HR+M+ P FH NI
Sbjct: 140 AGEKWSRHRRMLTPAFHFNI 159
>BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein.
Length = 524
Score = 62.9 bits (146), Expect = 6e-10
Identities = 34/87 (39%), Positives = 45/87 (51%), Gaps = 3/87 (3%)
Frame = +1
Query: 265 LVNLALGYAQTFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATE--YKFFKPWL 435
L L Y Q F ++WLG ++ L D I I ++ + Y F KPWL
Sbjct: 77 LTQLVTTYPQGF----KLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWL 132
Query: 436 GEGLLISSGPKWRSHRKMIAPTFHINI 516
G+GLL+S G KW HR+M+ P FH NI
Sbjct: 133 GDGLLLSGGDKWSRHRRMLTPAFHFNI 159
>AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein.
Length = 524
Score = 62.9 bits (146), Expect = 6e-10
Identities = 34/87 (39%), Positives = 45/87 (51%), Gaps = 3/87 (3%)
Frame = +1
Query: 265 LVNLALGYAQTFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATE--YKFFKPWL 435
L L Y Q F ++WLG ++ L D I I ++ + Y F KPWL
Sbjct: 77 LTQLVTTYPQGF----KLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWL 132
Query: 436 GEGLLISSGPKWRSHRKMIAPTFHINI 516
G+GLL+S G KW HR+M+ P FH NI
Sbjct: 133 GDGLLLSGGDKWSRHRRMLTPAFHFNI 159
>X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for
cytochrome P-450HP. ).
Length = 511
Score = 61.7 bits (143), Expect = 1e-09
Identities = 39/133 (29%), Positives = 58/133 (43%)
Frame = +1
Query: 118 LLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQT 297
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 298 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 477
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 478 HRKMIAPTFHINI 516
HRK++ P FH ++
Sbjct: 137 HRKLLTPGFHYDV 149
>DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 61.7 bits (143), Expect = 1e-09
Identities = 39/133 (29%), Positives = 58/133 (43%)
Frame = +1
Query: 118 LLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQT 297
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 298 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 477
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 478 HRKMIAPTFHINI 516
HRK++ P FH ++
Sbjct: 137 HRKLLTPGFHYDV 149
>BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 61.7 bits (143), Expect = 1e-09
Identities = 39/133 (29%), Positives = 58/133 (43%)
Frame = +1
Query: 118 LLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQT 297
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 298 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 477
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 478 HRKMIAPTFHINI 516
HRK++ P FH ++
Sbjct: 137 HRKLLTPGFHYDV 149
>AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P450
4B1 protein.
Length = 512
Score = 61.7 bits (143), Expect = 1e-09
Identities = 39/133 (29%), Positives = 58/133 (43%)
Frame = +1
Query: 118 LLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQT 297
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 298 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 477
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 478 HRKMIAPTFHINI 516
HRK++ P FH ++
Sbjct: 137 HRKLLTPGFHYDV 149
>AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 61.7 bits (143), Expect = 1e-09
Identities = 39/133 (29%), Positives = 58/133 (43%)
Frame = +1
Query: 118 LLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQT 297
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 298 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 477
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 478 HRKMIAPTFHINI 516
HRK++ P FH ++
Sbjct: 137 HRKLLTPGFHYDV 149
>AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 61.7 bits (143), Expect = 1e-09
Identities = 39/133 (29%), Positives = 58/133 (43%)
Frame = +1
Query: 118 LLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQT 297
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 298 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 477
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 478 HRKMIAPTFHINI 516
HRK++ P FH ++
Sbjct: 137 HRKLLTPGFHYDV 149
>AY064484-1|AAL57719.1| 295|Homo sapiens truncated cytochrome P450
protein.
Length = 295
Score = 61.7 bits (143), Expect = 1e-09
Identities = 39/133 (29%), Positives = 58/133 (43%)
Frame = +1
Query: 118 LLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQT 297
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 298 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 477
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 478 HRKMIAPTFHINI 516
HRK++ P FH ++
Sbjct: 137 HRKLLTPGFHYDV 149
>AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 61.7 bits (143), Expect = 1e-09
Identities = 39/133 (29%), Positives = 58/133 (43%)
Frame = +1
Query: 118 LLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQT 297
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 298 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 477
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 478 HRKMIAPTFHINI 516
HRK++ P FH ++
Sbjct: 137 HRKLLTPGFHYDV 149
>AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 61.7 bits (143), Expect = 1e-09
Identities = 39/133 (29%), Positives = 58/133 (43%)
Frame = +1
Query: 118 LLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQT 297
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 298 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 477
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 478 HRKMIAPTFHINI 516
HRK++ P FH ++
Sbjct: 137 HRKLLTPGFHYDV 149
>AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 61.7 bits (143), Expect = 1e-09
Identities = 39/133 (29%), Positives = 58/133 (43%)
Frame = +1
Query: 118 LLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQT 297
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 298 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 477
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 478 HRKMIAPTFHINI 516
HRK++ P FH ++
Sbjct: 137 HRKLLTPGFHYDV 149
>AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 61.7 bits (143), Expect = 1e-09
Identities = 39/133 (29%), Positives = 58/133 (43%)
Frame = +1
Query: 118 LLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQT 297
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 298 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 477
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 478 HRKMIAPTFHINI 516
HRK++ P FH ++
Sbjct: 137 HRKLLTPGFHYDV 149
>AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ39501 fis, clone PROST2016980, moderately
similar to CYTOCHROME P450 4F2 (EC 1.14.13.30). ).
Length = 531
Score = 61.7 bits (143), Expect = 1e-09
Identities = 29/74 (39%), Positives = 44/74 (59%), Gaps = 3/74 (4%)
Frame = +1
Query: 304 NVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATE--YKFFKPWLGEGLLISSGPKWR 474
+V+ VW+G L ++ L D I+ +L + + Y F KPWLG+GLL+S G KW
Sbjct: 94 HVLLVWMGPVLPLLVLVHPDYIKPLLGASAATAPKDDLFYGFLKPWLGDGLLLSKGDKWS 153
Query: 475 SHRKMIAPTFHINI 516
HR+++ P FH +I
Sbjct: 154 RHRRLLTPAFHFDI 167
>AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 61.7 bits (143), Expect = 1e-09
Identities = 39/133 (29%), Positives = 58/133 (43%)
Frame = +1
Query: 118 LLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQT 297
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 298 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 477
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 478 HRKMIAPTFHINI 516
HRK++ P FH ++
Sbjct: 137 HRKLLTPGFHYDV 149
>J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung
cytochrome P450 (IV subfamily) BI protein, complete cds.
).
Length = 511
Score = 60.1 bits (139), Expect = 5e-09
Identities = 38/133 (28%), Positives = 58/133 (43%)
Frame = +1
Query: 118 LLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQT 297
+LG I +L R + + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRRT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 298 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 477
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 478 HRKMIAPTFHINI 516
HRK++ P FH ++
Sbjct: 137 HRKLLTPGFHYDV 149
>S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 591
Score = 59.7 bits (138), Expect = 6e-09
Identities = 35/113 (30%), Positives = 56/113 (49%), Gaps = 1/113 (0%)
Frame = +1
Query: 181 KLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWL-GSKLIVFLADA 357
K + P P +FG+ L + + + + +TF + WL G K+ V L D
Sbjct: 46 KALQQFPCPPSHWLFGHIQELQQDQELQRIQK---WVETFPSACPHWLWGGKVRVQLYDP 102
Query: 358 DDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINI 516
D +++IL + Y+F PW+G GLL+ +G W HR+M+ P FH +I
Sbjct: 103 DYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDI 154
>S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 519
Score = 59.7 bits (138), Expect = 6e-09
Identities = 35/113 (30%), Positives = 56/113 (49%), Gaps = 1/113 (0%)
Frame = +1
Query: 181 KLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWL-GSKLIVFLADA 357
K + P P +FG+ L + + + + +TF + WL G K+ V L D
Sbjct: 46 KALQQFPCPPSHWLFGHIQELQQDQELQRIQK---WVETFPSACPHWLWGGKVRVQLYDP 102
Query: 358 DDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINI 516
D +++IL + Y+F PW+G GLL+ +G W HR+M+ P FH +I
Sbjct: 103 DYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDI 154
>L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein.
Length = 519
Score = 59.7 bits (138), Expect = 6e-09
Identities = 35/113 (30%), Positives = 56/113 (49%), Gaps = 1/113 (0%)
Frame = +1
Query: 181 KLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWL-GSKLIVFLADA 357
K + P P +FG+ L + + + + +TF + WL G K+ V L D
Sbjct: 46 KALQQFPCPPSHWLFGHIQELQQDQELQRIQK---WVETFPSACPHWLWGGKVRVQLYDP 102
Query: 358 DDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINI 516
D +++IL + Y+F PW+G GLL+ +G W HR+M+ P FH +I
Sbjct: 103 DYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDI 154
>D26481-1|BAA05491.1| 519|Homo sapiens fatty acids
omega-hydroxylase protein.
Length = 519
Score = 59.7 bits (138), Expect = 6e-09
Identities = 35/113 (30%), Positives = 56/113 (49%), Gaps = 1/113 (0%)
Frame = +1
Query: 181 KLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWL-GSKLIVFLADA 357
K + P P +FG+ L + + + + +TF + WL G K+ V L D
Sbjct: 46 KALQQFPCPPSHWLFGHIQELQQDQELQRIQK---WVETFPSACPHWLWGGKVRVQLYDP 102
Query: 358 DDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINI 516
D +++IL + Y+F PW+G GLL+ +G W HR+M+ P FH +I
Sbjct: 103 DYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDI 154
>D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 521
Score = 59.7 bits (138), Expect = 6e-09
Identities = 35/113 (30%), Positives = 56/113 (49%), Gaps = 1/113 (0%)
Frame = +1
Query: 181 KLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWL-GSKLIVFLADA 357
K + P P +FG+ L + + + + +TF + WL G K+ V L D
Sbjct: 46 KALQQFPCPPSHWLFGHIQELQQDQELQRIQK---WVETFPSACPHWLWGGKVRVQLYDP 102
Query: 358 DDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINI 516
D +++IL + Y+F PW+G GLL+ +G W HR+M+ P FH +I
Sbjct: 103 DYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDI 154
>BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein.
Length = 455
Score = 59.7 bits (138), Expect = 6e-09
Identities = 35/113 (30%), Positives = 56/113 (49%), Gaps = 1/113 (0%)
Frame = +1
Query: 181 KLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWL-GSKLIVFLADA 357
K + P P +FG+ L + + + + +TF + WL G K+ V L D
Sbjct: 46 KALQQFPCPPSHWLFGHIQELQQDQELQRIQK---WVETFPSACPHWLWGGKVRVQLYDP 102
Query: 358 DDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINI 516
D +++IL + Y+F PW+G GLL+ +G W HR+M+ P FH +I
Sbjct: 103 DYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDI 154
>BC022851-1|AAH22851.1| 215|Homo sapiens CYP4A11 protein protein.
Length = 215
Score = 59.7 bits (138), Expect = 6e-09
Identities = 35/113 (30%), Positives = 56/113 (49%), Gaps = 1/113 (0%)
Frame = +1
Query: 181 KLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWL-GSKLIVFLADA 357
K + P P +FG+ L + + + + +TF + WL G K+ V L D
Sbjct: 46 KALQQFPCPPSHWLFGHIQELQQDQELQRIQK---WVETFPSACPHWLWGGKVRVQLYDP 102
Query: 358 DDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINI 516
D +++IL + Y+F PW+G GLL+ +G W HR+M+ P FH +I
Sbjct: 103 DYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDI 154
>AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 59.7 bits (138), Expect = 6e-09
Identities = 35/113 (30%), Positives = 56/113 (49%), Gaps = 1/113 (0%)
Frame = +1
Query: 181 KLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWL-GSKLIVFLADA 357
K + P P +FG+ L + + + + +TF + WL G K+ V L D
Sbjct: 46 KALQQFPCPPSHWLFGHIQELQQDQELQRIQK---WVETFPSACPHWLWGGKVRVQLYDP 102
Query: 358 DDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINI 516
D +++IL + Y+F PW+G GLL+ +G W HR+M+ P FH +I
Sbjct: 103 DYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDI 154
>AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 455
Score = 59.7 bits (138), Expect = 6e-09
Identities = 35/113 (30%), Positives = 56/113 (49%), Gaps = 1/113 (0%)
Frame = +1
Query: 181 KLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWL-GSKLIVFLADA 357
K + P P +FG+ L + + + + +TF + WL G K+ V L D
Sbjct: 46 KALQQFPCPPSHWLFGHIQELQQDQELQRIQK---WVETFPSACPHWLWGGKVRVQLYDP 102
Query: 358 DDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINI 516
D +++IL + Y+F PW+G GLL+ +G W HR+M+ P FH +I
Sbjct: 103 DYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDI 154
>AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 59.7 bits (138), Expect = 6e-09
Identities = 35/113 (30%), Positives = 56/113 (49%), Gaps = 1/113 (0%)
Frame = +1
Query: 181 KLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWL-GSKLIVFLADA 357
K + P P +FG+ L + + + + +TF + WL G K+ V L D
Sbjct: 46 KALQQFPCPPSHWLFGHIQELQQDQELQRIQK---WVETFPSACPHWLWGGKVRVQLYDP 102
Query: 358 DDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINI 516
D +++IL + Y+F PW+G GLL+ +G W HR+M+ P FH +I
Sbjct: 103 DYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDI 154
>AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfamily
IVA, polypeptide 11 protein.
Length = 519
Score = 59.7 bits (138), Expect = 6e-09
Identities = 35/113 (30%), Positives = 56/113 (49%), Gaps = 1/113 (0%)
Frame = +1
Query: 181 KLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWL-GSKLIVFLADA 357
K + P P +FG+ L + + + + +TF + WL G K+ V L D
Sbjct: 46 KALQQFPCPPSHWLFGHIQELQQDQELQRIQK---WVETFPSACPHWLWGGKVRVQLYDP 102
Query: 358 DDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINI 516
D +++IL + Y+F PW+G GLL+ +G W HR+M+ P FH +I
Sbjct: 103 DYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDI 154
>AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22
protein.
Length = 519
Score = 56.8 bits (131), Expect = 4e-08
Identities = 28/76 (36%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
Frame = +1
Query: 292 QTFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPK 468
+TF + W+ G K+ V L D D +++IL + YKF PW+G LL+ +G
Sbjct: 80 KTFPSACPYWIWGGKVRVQLYDPDYMKVILGRSDSKSHGS-YKFLAPWIGYSLLLLNGQT 138
Query: 469 WRSHRKMIAPTFHINI 516
W HR+M+ P FH +I
Sbjct: 139 WFQHRRMLTPAFHYDI 154
>BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein.
Length = 455
Score = 56.4 bits (130), Expect = 6e-08
Identities = 28/76 (36%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
Frame = +1
Query: 292 QTFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPK 468
+TF + W+ G K+ V L D D +++IL + YKF PW+G LL+ +G
Sbjct: 80 KTFPSACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPWIGYSLLLLNGQT 138
Query: 469 WRSHRKMIAPTFHINI 516
W HR+M+ P FH +I
Sbjct: 139 WFQHRRMLTPAFHYDI 154
>AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K
protein.
Length = 519
Score = 56.4 bits (130), Expect = 6e-08
Identities = 28/76 (36%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
Frame = +1
Query: 292 QTFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPK 468
+TF + W+ G K+ V L D D +++IL + YKF PW+G LL+ +G
Sbjct: 80 KTFPSACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPWIGYSLLLLNGQT 138
Query: 469 WRSHRKMIAPTFHINI 516
W HR+M+ P FH +I
Sbjct: 139 WFQHRRMLTPAFHYDI 154
>BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein.
Length = 357
Score = 53.2 bits (122), Expect = 5e-07
Identities = 28/76 (36%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
Frame = +1
Query: 292 QTFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPK 468
+TF + W+ G K+ V L D D +++IL + YKF P +G GLL+ +G
Sbjct: 80 KTFPSACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPRIGYGLLLLNGQT 138
Query: 469 WRSHRKMIAPTFHINI 516
W HR+M+ P FH +I
Sbjct: 139 WFQHRRMLTPAFHYDI 154
>AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 455
Score = 52.4 bits (120), Expect = 9e-07
Identities = 28/76 (36%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
Frame = +1
Query: 292 QTFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPK 468
+TF + W+ G K+ V L D D +++IL + YKF P +G GLL+ +G
Sbjct: 80 KTFPSACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPRIGYGLLLLNGQT 138
Query: 469 WRSHRKMIAPTFHINI 516
W HR+M+ P FH +I
Sbjct: 139 WFQHRRMLTPAFHNDI 154
>AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 421
Score = 52.4 bits (120), Expect = 9e-07
Identities = 28/76 (36%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
Frame = +1
Query: 292 QTFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPK 468
+TF + W+ G K+ V L D D +++IL + YKF P +G GLL+ +G
Sbjct: 80 KTFPSACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPRIGYGLLLLNGQT 138
Query: 469 WRSHRKMIAPTFHINI 516
W HR+M+ P FH +I
Sbjct: 139 WFQHRRMLTPAFHNDI 154
>AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 22 protein.
Length = 519
Score = 52.4 bits (120), Expect = 9e-07
Identities = 28/76 (36%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
Frame = +1
Query: 292 QTFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPK 468
+TF + W+ G K+ V L D D +++IL + YKF P +G GLL+ +G
Sbjct: 80 KTFPSACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPRIGYGLLLLNGQT 138
Query: 469 WRSHRKMIAPTFHINI 516
W HR+M+ P FH +I
Sbjct: 139 WFQHRRMLTPAFHNDI 154
>BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 52.0 bits (119), Expect = 1e-06
Identities = 44/142 (30%), Positives = 65/142 (45%), Gaps = 5/142 (3%)
Frame = +1
Query: 106 IFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIP--IFGNALTLMRKDPHELVNLA 279
+F LGL AI + R Q+ L +L P PAP G+ + + +L +
Sbjct: 19 VFCLALGLLQAIKLYLRRQR-----LLRDLRPFPAPPTHWFLGHQKFIQDDNMEKLEEII 73
Query: 280 LGYAQTFGNVVRVWLGSKLIVF-LADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLL 450
Y + F W+G F + D D + +L+ D ++Y KF P LG+GL
Sbjct: 74 EKYPRAFP----FWIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLA 126
Query: 451 ISSGPKWRSHRKMIAPTFHINI 516
GPKW HR+++ P FH NI
Sbjct: 127 ALDGPKWFQHRRLLTPGFHFNI 148
>AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein.
Length = 509
Score = 52.0 bits (119), Expect = 1e-06
Identities = 44/142 (30%), Positives = 65/142 (45%), Gaps = 5/142 (3%)
Frame = +1
Query: 106 IFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIP--IFGNALTLMRKDPHELVNLA 279
+F LGL AI + R Q+ L +L P PAP G+ + + +L +
Sbjct: 19 VFCLALGLLQAIKLYLRRQR-----LLRDLRPFPAPPTHWFLGHQKFIQDDNMEKLEEII 73
Query: 280 LGYAQTFGNVVRVWLGSKLIVF-LADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLL 450
Y + F W+G F + D D + +L+ D ++Y KF P LG+GL
Sbjct: 74 EKYPRAFP----FWIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLA 126
Query: 451 ISSGPKWRSHRKMIAPTFHINI 516
GPKW HR+++ P FH NI
Sbjct: 127 ALDGPKWFQHRRLLTPGFHFNI 148
>AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein.
Length = 509
Score = 52.0 bits (119), Expect = 1e-06
Identities = 44/142 (30%), Positives = 65/142 (45%), Gaps = 5/142 (3%)
Frame = +1
Query: 106 IFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIP--IFGNALTLMRKDPHELVNLA 279
+F LGL AI + R Q+ L +L P PAP G+ + + +L +
Sbjct: 19 VFCLALGLLQAIKLYLRRQR-----LLRDLRPFPAPPTHWFLGHQKFIQDDNMEKLEEII 73
Query: 280 LGYAQTFGNVVRVWLGSKLIVF-LADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLL 450
Y + F W+G F + D D + +L+ D ++Y KF P LG+GL
Sbjct: 74 EKYPRAFP----FWIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLA 126
Query: 451 ISSGPKWRSHRKMIAPTFHINI 516
GPKW HR+++ P FH NI
Sbjct: 127 ALDGPKWFQHRRLLTPGFHFNI 148
>AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 52.0 bits (119), Expect = 1e-06
Identities = 44/142 (30%), Positives = 65/142 (45%), Gaps = 5/142 (3%)
Frame = +1
Query: 106 IFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIP--IFGNALTLMRKDPHELVNLA 279
+F LGL AI + R Q+ L +L P PAP G+ + + +L +
Sbjct: 19 VFCLALGLLQAIKLYLRRQR-----LLRDLRPFPAPPTHWFLGHQKFIQDDNMEKLEEII 73
Query: 280 LGYAQTFGNVVRVWLGSKLIVF-LADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLL 450
Y + F W+G F + D D + +L+ D ++Y KF P LG+GL
Sbjct: 74 EKYPRAFP----FWIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLA 126
Query: 451 ISSGPKWRSHRKMIAPTFHINI 516
GPKW HR+++ P FH NI
Sbjct: 127 ALDGPKWFQHRRLLTPGFHFNI 148
>AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 509
Score = 52.0 bits (119), Expect = 1e-06
Identities = 44/142 (30%), Positives = 65/142 (45%), Gaps = 5/142 (3%)
Frame = +1
Query: 106 IFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIP--IFGNALTLMRKDPHELVNLA 279
+F LGL AI + R Q+ L +L P PAP G+ + + +L +
Sbjct: 19 VFCLALGLLQAIKLYLRRQR-----LLRDLRPFPAPPTHWFLGHQKFIQDDNMEKLEEII 73
Query: 280 LGYAQTFGNVVRVWLGSKLIVF-LADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLL 450
Y + F W+G F + D D + +L+ D ++Y KF P LG+GL
Sbjct: 74 EKYPRAFP----FWIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLA 126
Query: 451 ISSGPKWRSHRKMIAPTFHINI 516
GPKW HR+++ P FH NI
Sbjct: 127 ALDGPKWFQHRRLLTPGFHFNI 148
>AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid
omega-hydroxylase CYP4A11 protein.
Length = 519
Score = 51.2 bits (117), Expect = 2e-06
Identities = 27/76 (35%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
Frame = +1
Query: 292 QTFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPK 468
+TF + W+ G K+ V L D D +++IL + Y+F P +G GLL+ +G
Sbjct: 80 KTFPSACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPRIGYGLLLLNGQT 138
Query: 469 WRSHRKMIAPTFHINI 516
W HR+M+ P FH +I
Sbjct: 139 WFQHRRMLTPAFHNDI 154
>AY696295-1|AAU10524.1| 292|Homo sapiens cytochrome P450 protein.
Length = 292
Score = 50.8 bits (116), Expect = 3e-06
Identities = 23/70 (32%), Positives = 41/70 (58%), Gaps = 1/70 (1%)
Frame = +1
Query: 310 VRVWLGSKLIVF-LADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRK 486
V +W+G + F + D D ++I+L + A +K + W+G GL+ G KW+ HR+
Sbjct: 80 VPLWVGPFTMFFNIHDPDYVKILLKRQ-NPKSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138
Query: 487 MIAPTFHINI 516
++ P F+I+I
Sbjct: 139 IVKPGFNISI 148
>M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein.
Length = 377
Score = 50.0 bits (114), Expect = 5e-06
Identities = 35/127 (27%), Positives = 62/127 (48%), Gaps = 2/127 (1%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGN 306
LT + +L + NSH L PGP P+P+ GN L++ D L+ L + + +G+
Sbjct: 12 LTGLLLLLVQRHPNSH----GTLPPGPRPLPLLGN---LLQMDRRGLLKSFLRFREKYGD 64
Query: 307 VVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKP-WLGEGLLISSGPKWRSH 480
V V LG + +V L + I E ++++ + P + G G+L ++G +W+
Sbjct: 65 VFTVHLGPRPVVMLCGVEAIREALVDNAEAFSGRGKIVIMDPVYQGYGMLFANGNRWKVL 124
Query: 481 RKMIAPT 501
R+ T
Sbjct: 125 RRFSVTT 131
>BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein.
Length = 377
Score = 50.0 bits (114), Expect = 5e-06
Identities = 35/127 (27%), Positives = 62/127 (48%), Gaps = 2/127 (1%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGN 306
LT + +L + NSH L PGP P+P+ GN L++ D L+ L + + +G+
Sbjct: 12 LTGLLLLLVQRHPNSH----GTLPPGPRPLPLLGN---LLQMDRRGLLKSFLRFREKYGD 64
Query: 307 VVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKP-WLGEGLLISSGPKWRSH 480
V V LG + +V L + I E ++++ + P + G G+L ++G +W+
Sbjct: 65 VFTVHLGPRPVVMLCGVEAIREALVDNAEAFSGRGKIVIMDPVYQGYGMLFANGNRWKVL 124
Query: 481 RKMIAPT 501
R+ T
Sbjct: 125 RRFSVTT 131
>AK097373-1|BAC05026.1| 340|Homo sapiens protein ( Homo sapiens
cDNA FLJ40054 fis, clone TBAES2000315, weakly similar to
CYTOCHROME P450 4A1 (EC 1.14.15.3). ).
Length = 340
Score = 50.0 bits (114), Expect = 5e-06
Identities = 23/70 (32%), Positives = 40/70 (57%), Gaps = 1/70 (1%)
Frame = +1
Query: 310 VRVWLGSKLIVF-LADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRK 486
V +W+G + F + D D ++I+L A +K + W+G GL+ G KW+ HR+
Sbjct: 80 VPLWVGPFTMFFNIHDPDYVKILLKRQ-DPKSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138
Query: 487 MIAPTFHINI 516
++ P F+I+I
Sbjct: 139 IVKPGFNISI 148
>AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein.
Length = 505
Score = 49.6 bits (113), Expect = 6e-06
Identities = 22/69 (31%), Positives = 35/69 (50%)
Frame = +1
Query: 310 VRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKM 489
V +W+G + F D IL A +K + W+G GL+ G KW+ HR++
Sbjct: 80 VPLWVGPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQI 139
Query: 490 IAPTFHINI 516
+ P F+I+I
Sbjct: 140 VKPGFNISI 148
>AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein.
Length = 505
Score = 49.6 bits (113), Expect = 6e-06
Identities = 22/69 (31%), Positives = 35/69 (50%)
Frame = +1
Query: 310 VRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKM 489
V +W+G + F D IL A +K + W+G GL+ G KW+ HR++
Sbjct: 80 VPLWVGPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQI 139
Query: 490 IAPTFHINI 516
+ P F+I+I
Sbjct: 140 VKPGFNISI 148
>AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 49.6 bits (113), Expect = 6e-06
Identities = 22/69 (31%), Positives = 35/69 (50%)
Frame = +1
Query: 310 VRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKM 489
V +W+G + F D IL A +K + W+G GL+ G KW+ HR++
Sbjct: 80 VPLWVGPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQI 139
Query: 490 IAPTFHINI 516
+ P F+I+I
Sbjct: 140 VKPGFNISI 148
>AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 49.6 bits (113), Expect = 6e-06
Identities = 22/69 (31%), Positives = 35/69 (50%)
Frame = +1
Query: 310 VRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKM 489
V +W+G + F D IL A +K + W+G GL+ G KW+ HR++
Sbjct: 80 VPLWVGPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQI 139
Query: 490 IAPTFHINI 516
+ P F+I+I
Sbjct: 140 VKPGFNISI 148
>AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ16384 fis, clone TLIVE2007607, weakly similar
to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 508
Score = 48.0 bits (109), Expect = 2e-05
Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 3/69 (4%)
Frame = +1
Query: 319 WLGSKLIVF-LADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLLISSGPKWRSHRKM 489
W+G F + D D + +L+ D ++Y KF P LG+GL GPKW HR++
Sbjct: 82 WIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 138
Query: 490 IAPTFHINI 516
+ P FH NI
Sbjct: 139 LTPGFHFNI 147
>AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens
cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 444
Score = 48.0 bits (109), Expect = 2e-05
Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 3/69 (4%)
Frame = +1
Query: 319 WLGSKLIVF-LADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLLISSGPKWRSHRKM 489
W+G F + D D + +L+ D ++Y KF P LG+GL GPKW HR++
Sbjct: 18 WIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 74
Query: 490 IAPTFHINI 516
+ P FH NI
Sbjct: 75 LTPGFHFNI 83
>M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein.
Length = 491
Score = 47.2 bits (107), Expect = 3e-05
Identities = 33/127 (25%), Positives = 61/127 (48%), Gaps = 2/127 (1%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGN 306
LT + +L + N+H L PGP P+P+ GN L++ D L+ L + + +G+
Sbjct: 12 LTGLLLLLVQRHPNTH----DRLPPGPRPLPLLGN---LLQMDRRGLLKSFLRFREKYGD 64
Query: 307 VVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL-GEGLLISSGPKWRSH 480
V V LG + +V L + I E +++ + P+ G G++ ++G +W+
Sbjct: 65 VFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVL 124
Query: 481 RKMIAPT 501
R+ T
Sbjct: 125 RRFSVTT 131
>J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrome
P450IIE1 (ethanol-inducible) gene, complete cds. ).
Length = 493
Score = 47.2 bits (107), Expect = 3e-05
Identities = 38/136 (27%), Positives = 61/136 (44%), Gaps = 9/136 (6%)
Frame = +1
Query: 121 LGLTTA--IWILY-----RWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKD-PHELVNL 276
LG+T A +W + W+Q +H L PGP P+PI GN L K+ P L
Sbjct: 4 LGVTVALLVWAAFLLLVSMWRQ---VHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRL 60
Query: 277 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWLGEGLLI 453
AQ FG V +++GS+ +V + + E +L+ + F G++
Sbjct: 61 ----AQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIF 116
Query: 454 SSGPKWRSHRKMIAPT 501
++GP W+ R+ T
Sbjct: 117 NNGPTWKDIRRFSLTT 132
>J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrome
P-450j mRNA, complete cds. ).
Length = 493
Score = 47.2 bits (107), Expect = 3e-05
Identities = 38/136 (27%), Positives = 61/136 (44%), Gaps = 9/136 (6%)
Frame = +1
Query: 121 LGLTTA--IWILY-----RWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKD-PHELVNL 276
LG+T A +W + W+Q +H L PGP P+PI GN L K+ P L
Sbjct: 4 LGVTVALLVWAAFLLLVSMWRQ---VHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRL 60
Query: 277 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWLGEGLLI 453
AQ FG V +++GS+ +V + + E +L+ + F G++
Sbjct: 61 ----AQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIF 116
Query: 454 SSGPKWRSHRKMIAPT 501
++GP W+ R+ T
Sbjct: 117 NNGPTWKDIRRFSLTT 132
>DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 47.2 bits (107), Expect = 3e-05
Identities = 38/136 (27%), Positives = 61/136 (44%), Gaps = 9/136 (6%)
Frame = +1
Query: 121 LGLTTA--IWILY-----RWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKD-PHELVNL 276
LG+T A +W + W+Q +H L PGP P+PI GN L K+ P L
Sbjct: 4 LGVTVALLVWAAFLLLVSMWRQ---VHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRL 60
Query: 277 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWLGEGLLI 453
AQ FG V +++GS+ +V + + E +L+ + F G++
Sbjct: 61 ----AQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIF 116
Query: 454 SSGPKWRSHRKMIAPT 501
++GP W+ R+ T
Sbjct: 117 NNGPTWKDIRRFSLTT 132
>DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 47.2 bits (107), Expect = 3e-05
Identities = 33/127 (25%), Positives = 61/127 (48%), Gaps = 2/127 (1%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGN 306
LT + +L + N+H L PGP P+P+ GN L++ D L+ L + + +G+
Sbjct: 12 LTGLLLLLVQRHPNTH----DRLPPGPRPLPLLGN---LLQMDRRGLLKSFLRFREKYGD 64
Query: 307 VVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL-GEGLLISSGPKWRSH 480
V V LG + +V L + I E +++ + P+ G G++ ++G +W+
Sbjct: 65 VFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVL 124
Query: 481 RKMIAPT 501
R+ T
Sbjct: 125 RRFSVTT 131
>DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1
protein.
Length = 493
Score = 47.2 bits (107), Expect = 3e-05
Identities = 38/136 (27%), Positives = 61/136 (44%), Gaps = 9/136 (6%)
Frame = +1
Query: 121 LGLTTA--IWILY-----RWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKD-PHELVNL 276
LG+T A +W + W+Q +H L PGP P+PI GN L K+ P L
Sbjct: 4 LGVTVALLVWAAFLLLVSMWRQ---VHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRL 60
Query: 277 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWLGEGLLI 453
AQ FG V +++GS+ +V + + E +L+ + F G++
Sbjct: 61 ----AQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIF 116
Query: 454 SSGPKWRSHRKMIAPT 501
++GP W+ R+ T
Sbjct: 117 NNGPTWKDIRRFSLTT 132
>BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 47.2 bits (107), Expect = 3e-05
Identities = 38/136 (27%), Positives = 61/136 (44%), Gaps = 9/136 (6%)
Frame = +1
Query: 121 LGLTTA--IWILY-----RWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKD-PHELVNL 276
LG+T A +W + W+Q +H L PGP P+PI GN L K+ P L
Sbjct: 4 LGVTVALLVWAAFLLLVSMWRQ---VHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRL 60
Query: 277 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWLGEGLLI 453
AQ FG V +++GS+ +V + + E +L+ + F G++
Sbjct: 61 ----AQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIF 116
Query: 454 SSGPKWRSHRKMIAPT 501
++GP W+ R+ T
Sbjct: 117 NNGPAWKDIRRFSLTT 132
>BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 47.2 bits (107), Expect = 3e-05
Identities = 33/127 (25%), Positives = 61/127 (48%), Gaps = 2/127 (1%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGN 306
LT + +L + N+H L PGP P+P+ GN L++ D L+ L + + +G+
Sbjct: 12 LTGLLLLLVQRHPNTH----DRLPPGPRPLPLLGN---LLQMDRRGLLKSFLRFREKYGD 64
Query: 307 VVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL-GEGLLISSGPKWRSH 480
V V LG + +V L + I E +++ + P+ G G++ ++G +W+
Sbjct: 65 VFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVL 124
Query: 481 RKMIAPT 501
R+ T
Sbjct: 125 RRFSVTT 131
>BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 47.2 bits (107), Expect = 3e-05
Identities = 33/127 (25%), Positives = 61/127 (48%), Gaps = 2/127 (1%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGN 306
LT + +L + N+H L PGP P+P+ GN L++ D L+ L + + +G+
Sbjct: 12 LTGLLLLLVQRHPNTH----DRLPPGPRPLPLLGN---LLQMDRRGLLKSFLRFREKYGD 64
Query: 307 VVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL-GEGLLISSGPKWRSH 480
V V LG + +V L + I E +++ + P+ G G++ ++G +W+
Sbjct: 65 VFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVL 124
Query: 481 RKMIAPT 501
R+ T
Sbjct: 125 RRFSVTT 131
>AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 47.2 bits (107), Expect = 3e-05
Identities = 38/136 (27%), Positives = 61/136 (44%), Gaps = 9/136 (6%)
Frame = +1
Query: 121 LGLTTA--IWILY-----RWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKD-PHELVNL 276
LG+T A +W + W+Q +H L PGP P+PI GN L K+ P L
Sbjct: 4 LGVTVALLVWAAFLLLVSMWRQ---VHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRL 60
Query: 277 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWLGEGLLI 453
AQ FG V +++GS+ +V + + E +L+ + F G++
Sbjct: 61 ----AQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIF 116
Query: 454 SSGPKWRSHRKMIAPT 501
++GP W+ R+ T
Sbjct: 117 NNGPTWKDIRRFSLTT 132
>AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6
protein.
Length = 491
Score = 47.2 bits (107), Expect = 3e-05
Identities = 33/127 (25%), Positives = 61/127 (48%), Gaps = 2/127 (1%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGN 306
LT + +L + N+H L PGP P+P+ GN L++ D L+ L + + +G+
Sbjct: 12 LTGLLLLLVQRHPNTH----DRLPPGPRPLPLLGN---LLQMDRRGLLKSFLRFREKYGD 64
Query: 307 VVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL-GEGLLISSGPKWRSH 480
V V LG + +V L + I E +++ + P+ G G++ ++G +W+
Sbjct: 65 VFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVL 124
Query: 481 RKMIAPT 501
R+ T
Sbjct: 125 RRFSVTT 131
>AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1
protein.
Length = 493
Score = 47.2 bits (107), Expect = 3e-05
Identities = 38/136 (27%), Positives = 61/136 (44%), Gaps = 9/136 (6%)
Frame = +1
Query: 121 LGLTTA--IWILY-----RWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKD-PHELVNL 276
LG+T A +W + W+Q +H L PGP P+PI GN L K+ P L
Sbjct: 4 LGVTVALLVWAAFLLLVSMWRQ---VHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRL 60
Query: 277 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWLGEGLLI 453
AQ FG V +++GS+ +V + + E +L+ + F G++
Sbjct: 61 ----AQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIF 116
Query: 454 SSGPKWRSHRKMIAPT 501
++GP W+ R+ T
Sbjct: 117 NNGPTWKDIRRFSLTT 132
>AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein.
Length = 491
Score = 47.2 bits (107), Expect = 3e-05
Identities = 33/127 (25%), Positives = 61/127 (48%), Gaps = 2/127 (1%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGN 306
LT + +L + N+H L PGP P+P+ GN L++ D L+ L + + +G+
Sbjct: 12 LTGLLLLLVQRHPNTH----DRLPPGPRPLPLLGN---LLQMDRRGLLKSFLRFREKYGD 64
Query: 307 VVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL-GEGLLISSGPKWRSH 480
V V LG + +V L + I E +++ + P+ G G++ ++G +W+
Sbjct: 65 VFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVL 124
Query: 481 RKMIAPT 501
R+ T
Sbjct: 125 RRFSVTT 131
>X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mRNA
for P-450 IIA4 protein. ).
Length = 494
Score = 46.8 bits (106), Expect = 5e-05
Identities = 36/138 (26%), Positives = 63/138 (45%), Gaps = 3/138 (2%)
Frame = +1
Query: 97 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNL 276
S ++ LL T + ++ WQQ KL PGP P+P GN L L + ++ N
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 277 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 447
+ ++ +G V + LG + +V L D + E +++ E F W+ G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 448 LISSGPKWRSHRKMIAPT 501
+ S+G + + R+ T
Sbjct: 117 VFSNGERAKQLRRFSIAT 134
>X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for
cytochrome P-450IIA. ).
Length = 489
Score = 46.8 bits (106), Expect = 5e-05
Identities = 35/136 (25%), Positives = 63/136 (46%), Gaps = 3/136 (2%)
Frame = +1
Query: 103 VIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLAL 282
++ LL T + ++ WQQ + KL PGP P+P GN L L + ++ N +
Sbjct: 1 MLLVALLVCLTVMVLMSVWQQRKNKGKLP---PGPTPLPFIGNYLQL---NTEQMYNSLM 54
Query: 283 GYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGLLI 453
++ +G V + LG + +V L D + E +++ E F W+ G G++
Sbjct: 55 KISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGVVF 113
Query: 454 SSGPKWRSHRKMIAPT 501
S+G + + R+ T
Sbjct: 114 SNGERAKQLRRFSIAT 129
>U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 46.8 bits (106), Expect = 5e-05
Identities = 36/138 (26%), Positives = 62/138 (44%), Gaps = 3/138 (2%)
Frame = +1
Query: 97 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNL 276
S ++ LL T + ++ W+Q KL PGP P+P GN L L + ++ N
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 277 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 447
+ ++ +G V + LG + +V L D + E +++ E F WL G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATF-DWLFKGYGV 116
Query: 448 LISSGPKWRSHRKMIAPT 501
S+G + + R+ T
Sbjct: 117 AFSNGERAKQLRRFSIAT 134
>M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 46.8 bits (106), Expect = 5e-05
Identities = 36/138 (26%), Positives = 63/138 (45%), Gaps = 3/138 (2%)
Frame = +1
Query: 97 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNL 276
S ++ LL T + ++ WQQ KL PGP P+P GN L L + ++ N
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 277 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 447
+ ++ +G V + LG + +V L D + E +++ E F W+ G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 448 LISSGPKWRSHRKMIAPT 501
+ S+G + + R+ T
Sbjct: 117 VFSNGERAKQLRRFSIAT 134
>EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 321
Score = 46.8 bits (106), Expect = 5e-05
Identities = 29/101 (28%), Positives = 51/101 (50%), Gaps = 2/101 (1%)
Frame = +1
Query: 190 ELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDI- 366
+L PGP P+PI GN L L +D ++ ++ +G++ V LG + +V L+ +
Sbjct: 29 KLPPGPRPLPILGNLLLLCSQD---MLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVK 85
Query: 367 EIILNSHVHIDKATEY-KFFKPWLGEGLLISSGPKWRSHRK 486
E +++ +Y FF G G+ SSG +W+ R+
Sbjct: 86 EALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQ 126
>BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 46.8 bits (106), Expect = 5e-05
Identities = 36/138 (26%), Positives = 63/138 (45%), Gaps = 3/138 (2%)
Frame = +1
Query: 97 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNL 276
S ++ LL T + ++ WQQ KL PGP P+P GN L L + ++ N
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 277 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 447
+ ++ +G V + LG + +V L D + E +++ E F W+ G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 448 LISSGPKWRSHRKMIAPT 501
+ S+G + + R+ T
Sbjct: 117 VFSNGERAKQLRRFSIAT 134
>BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 46.8 bits (106), Expect = 5e-05
Identities = 36/138 (26%), Positives = 63/138 (45%), Gaps = 3/138 (2%)
Frame = +1
Query: 97 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNL 276
S ++ LL T + ++ WQQ KL PGP P+P GN L L + ++ N
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 277 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 447
+ ++ +G V + LG + +V L D + E +++ E F W+ G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 448 LISSGPKWRSHRKMIAPT 501
+ S+G + + R+ T
Sbjct: 117 VFSNGERAKQLRRFSIAT 134
>BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 46.8 bits (106), Expect = 5e-05
Identities = 36/138 (26%), Positives = 63/138 (45%), Gaps = 3/138 (2%)
Frame = +1
Query: 97 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNL 276
S ++ LL T + ++ WQQ KL PGP P+P GN L L + ++ N
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 277 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 447
+ ++ +G V + LG + +V L D + E +++ E F W+ G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 448 LISSGPKWRSHRKMIAPT 501
+ S+G + + R+ T
Sbjct: 117 VFSNGERAKQLRRFSIAT 134
>BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 46.8 bits (106), Expect = 5e-05
Identities = 36/138 (26%), Positives = 63/138 (45%), Gaps = 3/138 (2%)
Frame = +1
Query: 97 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNL 276
S ++ LL T + ++ WQQ KL PGP P+P GN L L + ++ N
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 277 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 447
+ ++ +G V + LG + +V L D + E +++ E F W+ G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 448 LISSGPKWRSHRKMIAPT 501
+ S+G + + R+ T
Sbjct: 117 VFSNGERAKQLRRFSIAT 134
>AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13
variant 6 protein.
Length = 494
Score = 46.8 bits (106), Expect = 5e-05
Identities = 36/138 (26%), Positives = 62/138 (44%), Gaps = 3/138 (2%)
Frame = +1
Query: 97 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNL 276
S ++ LL T + ++ W+Q KL PGP P+P GN L L + ++ N
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 277 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 447
+ ++ +G V + LG + +V L D + E +++ E F WL G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATF-DWLFKGYGV 116
Query: 448 LISSGPKWRSHRKMIAPT 501
S+G + + R+ T
Sbjct: 117 AFSNGERAKQLRRFSIAT 134
>AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13
variant 5 protein.
Length = 494
Score = 46.8 bits (106), Expect = 5e-05
Identities = 36/138 (26%), Positives = 62/138 (44%), Gaps = 3/138 (2%)
Frame = +1
Query: 97 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNL 276
S ++ LL T + ++ W+Q KL PGP P+P GN L L + ++ N
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 277 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 447
+ ++ +G V + LG + +V L D + E +++ E F WL G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATF-DWLFKGYGV 116
Query: 448 LISSGPKWRSHRKMIAPT 501
S+G + + R+ T
Sbjct: 117 AFSNGERAKQLRRFSIAT 134
>AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13
variant 3 protein.
Length = 494
Score = 46.8 bits (106), Expect = 5e-05
Identities = 36/138 (26%), Positives = 62/138 (44%), Gaps = 3/138 (2%)
Frame = +1
Query: 97 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNL 276
S ++ LL T + ++ W+Q KL PGP P+P GN L L + ++ N
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 277 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 447
+ ++ +G V + LG + +V L D + E +++ E F WL G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATF-DWLFKGYGV 116
Query: 448 LISSGPKWRSHRKMIAPT 501
S+G + + R+ T
Sbjct: 117 AFSNGERAKQLRRFSIAT 134
>AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13
variant 2 protein.
Length = 494
Score = 46.8 bits (106), Expect = 5e-05
Identities = 36/138 (26%), Positives = 62/138 (44%), Gaps = 3/138 (2%)
Frame = +1
Query: 97 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNL 276
S ++ LL T + ++ W+Q KL PGP P+P GN L L + ++ N
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 277 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 447
+ ++ +G V + LG + +V L D + E +++ E F WL G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATF-DWLFKGYGV 116
Query: 448 LISSGPKWRSHRKMIAPT 501
S+G + + R+ T
Sbjct: 117 AFSNGERAKQLRRFSIAT 134
>AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13
variant 1 protein.
Length = 494
Score = 46.8 bits (106), Expect = 5e-05
Identities = 36/138 (26%), Positives = 62/138 (44%), Gaps = 3/138 (2%)
Frame = +1
Query: 97 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNL 276
S ++ LL T + ++ W+Q KL PGP P+P GN L L + ++ N
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 277 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 447
+ ++ +G V + LG + +V L D + E +++ E F WL G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATF-DWLFKGYGV 116
Query: 448 LISSGPKWRSHRKMIAPT 501
S+G + + R+ T
Sbjct: 117 AFSNGERAKQLRRFSIAT 134
>AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13
protein.
Length = 494
Score = 46.8 bits (106), Expect = 5e-05
Identities = 36/138 (26%), Positives = 62/138 (44%), Gaps = 3/138 (2%)
Frame = +1
Query: 97 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNL 276
S ++ LL T + ++ W+Q KL PGP P+P GN L L + ++ N
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 277 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 447
+ ++ +G V + LG + +V L D + E +++ E F WL G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATF-DWLFKGYGV 116
Query: 448 LISSGPKWRSHRKMIAPT 501
S+G + + R+ T
Sbjct: 117 AFSNGERAKQLRRFSIAT 134
>AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6
protein.
Length = 494
Score = 46.8 bits (106), Expect = 5e-05
Identities = 36/138 (26%), Positives = 63/138 (45%), Gaps = 3/138 (2%)
Frame = +1
Query: 97 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNL 276
S ++ LL T + ++ WQQ KL PGP P+P GN L L + ++ N
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 277 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 447
+ ++ +G V + LG + +V L D + E +++ E F W+ G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 448 LISSGPKWRSHRKMIAPT 501
+ S+G + + R+ T
Sbjct: 117 VFSNGERAKQLRRFSIAT 134
>U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 46.4 bits (105), Expect = 6e-05
Identities = 34/127 (26%), Positives = 59/127 (46%), Gaps = 3/127 (2%)
Frame = +1
Query: 97 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNL 276
S ++ LL T + ++ WQQ KL PGP P+P GN L L + ++ N
Sbjct: 4 SGMLLVALLACLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 277 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 447
+ ++ +G V + LG + +V L D + E +++ E F W+ G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 448 LISSGPK 468
+ S+G +
Sbjct: 117 VFSNGER 123
>M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 46.4 bits (105), Expect = 6e-05
Identities = 35/125 (28%), Positives = 60/125 (48%), Gaps = 2/125 (1%)
Frame = +1
Query: 133 TAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVV 312
+ +++L W+Q+S +L GP P+PI GN L L KD + + +++ +G V
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVKDMSKSLT---NFSKVYGPVF 65
Query: 313 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWRSHRK 486
V+ G K IV L + ++ L H + + K G G+L S+G +W+ R+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRR 125
Query: 487 MIAPT 501
T
Sbjct: 126 FCLMT 130
>L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18
protein.
Length = 490
Score = 46.4 bits (105), Expect = 6e-05
Identities = 35/125 (28%), Positives = 60/125 (48%), Gaps = 2/125 (1%)
Frame = +1
Query: 133 TAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVV 312
+ +++L W+Q+S +L GP P+PI GN L L KD + + +++ +G V
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVKDMSKSLT---NFSKVYGPVF 65
Query: 313 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWRSHRK 486
V+ G K IV L + ++ L H + + K G G+L S+G +W+ R+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRR 125
Query: 487 MIAPT 501
T
Sbjct: 126 FCLMT 130
>BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein.
Length = 431
Score = 46.4 bits (105), Expect = 6e-05
Identities = 35/125 (28%), Positives = 60/125 (48%), Gaps = 2/125 (1%)
Frame = +1
Query: 133 TAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVV 312
+ +++L W+Q+S +L GP P+PI GN L L KD + + +++ +G V
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVKDMSKSLT---NFSKVYGPVF 65
Query: 313 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWRSHRK 486
V+ G K IV L + ++ L H + + K G G+L S+G +W+ R+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRR 125
Query: 487 MIAPT 501
T
Sbjct: 126 FCLMT 130
>BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein.
Length = 443
Score = 46.4 bits (105), Expect = 6e-05
Identities = 35/125 (28%), Positives = 60/125 (48%), Gaps = 2/125 (1%)
Frame = +1
Query: 133 TAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVV 312
+ +++L W+Q+S +L GP P+PI GN L L KD + + +++ +G V
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVKDMSKSLT---NFSKVYGPVF 65
Query: 313 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWRSHRK 486
V+ G K IV L + ++ L H + + K G G+L S+G +W+ R+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRR 125
Query: 487 MIAPT 501
T
Sbjct: 126 FCLMT 130
>BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 46.4 bits (105), Expect = 6e-05
Identities = 35/125 (28%), Positives = 60/125 (48%), Gaps = 2/125 (1%)
Frame = +1
Query: 133 TAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVV 312
+ +++L W+Q+S +L GP P+PI GN L L KD + + +++ +G V
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVKDMSKSLT---NFSKVYGPVF 65
Query: 313 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWRSHRK 486
V+ G K IV L + ++ L H + + K G G+L S+G +W+ R+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRR 125
Query: 487 MIAPT 501
T
Sbjct: 126 FCLMT 130
>BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 46.4 bits (105), Expect = 6e-05
Identities = 35/125 (28%), Positives = 60/125 (48%), Gaps = 2/125 (1%)
Frame = +1
Query: 133 TAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVV 312
+ +++L W+Q+S +L GP P+PI GN L L KD + + +++ +G V
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVKDMSKSLT---NFSKVYGPVF 65
Query: 313 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWRSHRK 486
V+ G K IV L + ++ L H + + K G G+L S+G +W+ R+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRR 125
Query: 487 MIAPT 501
T
Sbjct: 126 FCLMT 130
>BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 46.4 bits (105), Expect = 6e-05
Identities = 35/125 (28%), Positives = 60/125 (48%), Gaps = 2/125 (1%)
Frame = +1
Query: 133 TAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVV 312
+ +++L W+Q+S +L GP P+PI GN L L KD + + +++ +G V
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVKDMSKSLT---NFSKVYGPVF 65
Query: 313 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWRSHRK 486
V+ G K IV L + ++ L H + + K G G+L S+G +W+ R+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRR 125
Query: 487 MIAPT 501
T
Sbjct: 126 FCLMT 130
>AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 46.4 bits (105), Expect = 6e-05
Identities = 35/125 (28%), Positives = 60/125 (48%), Gaps = 2/125 (1%)
Frame = +1
Query: 133 TAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVV 312
+ +++L W+Q+S +L GP P+PI GN L L KD + + +++ +G V
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVKDMSKSLT---NFSKVYGPVF 65
Query: 313 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWRSHRK 486
V+ G K IV L + ++ L H + + K G G+L S+G +W+ R+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRR 125
Query: 487 MIAPT 501
T
Sbjct: 126 FCLMT 130
>AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 variant protein.
Length = 490
Score = 46.0 bits (104), Expect = 8e-05
Identities = 35/125 (28%), Positives = 59/125 (47%), Gaps = 2/125 (1%)
Frame = +1
Query: 133 TAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVV 312
+ +++L W Q+S +L GP P+PI GN L L KD + + +++ +G V
Sbjct: 12 SCLFLLSLWGQSSGRGRLPS---GPTPLPIIGNILQLDVKDMSKSLT---NFSKVYGPVF 65
Query: 313 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWRSHRK 486
V+ G K IV L + ++ L H + + K G G+L S+G +W+ R+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFFGRGSFPVAEKVNKGLGILFSNGKRWKEIRR 125
Query: 487 MIAPT 501
T
Sbjct: 126 FCLMT 130
>BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 45.6 bits (103), Expect = 1e-04
Identities = 38/136 (27%), Positives = 60/136 (44%), Gaps = 9/136 (6%)
Frame = +1
Query: 121 LGLTTA--IWILY-----RWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKD-PHELVNL 276
LG+T A +W + W+Q +H L PGP P+PI GN L K+ P L
Sbjct: 4 LGVTVALLVWAAFLLLVSMWRQ---VHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRL 60
Query: 277 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWLGEGLLI 453
AQ FG V + +GS+ +V + + E +L+ + F G++
Sbjct: 61 ----AQRFGPVFTLCVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIF 116
Query: 454 SSGPKWRSHRKMIAPT 501
++GP W+ R+ T
Sbjct: 117 NNGPTWKDIRRFSLTT 132
>U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 45.2 bits (102), Expect = 1e-04
Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 3/127 (2%)
Frame = +1
Query: 97 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNL 276
S ++ LL T + ++ WQQ KL PGP P+P GN L L + + +
Sbjct: 4 SGLLLVALLACLTVMVLMSVWQQRKSRGKLP---PGPTPLPFIGNYLQL---NTEHICDS 57
Query: 277 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 447
+ +++ +G V + LG + +V L D + E +++ E F+ W+ G G+
Sbjct: 58 IMKFSECYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFE-WVFKGYGV 116
Query: 448 LISSGPK 468
S+G +
Sbjct: 117 AFSNGER 123
>S63426-1|ABB76283.1| 214|Homo sapiens (S)-mephenytoin hydroxylase
associated cytochrome P450 protein.
Length = 214
Score = 44.4 bits (100), Expect = 2e-04
Identities = 33/116 (28%), Positives = 57/116 (49%), Gaps = 2/116 (1%)
Frame = +1
Query: 133 TAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVV 312
+ +++L W+Q+S +L GP P+PI GN L L KD + + +++ +G V
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVKDMSKSLT---NFSKVYGPVF 65
Query: 313 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWR 474
V+ G K IV L + ++ L H + + K G G+L S+G +W+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWK 121
>M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 44.4 bits (100), Expect = 2e-04
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 3/127 (2%)
Frame = +1
Query: 97 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNL 276
S ++ LL T + ++ WQQ KL PGP P+P GN L L + + +
Sbjct: 4 SGLLLVALLACLTVMVLMSVWQQRKSRGKLP---PGPTPLPFIGNYLQL---NTEHICDS 57
Query: 277 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 447
+ +++ +G V + LG + +V L D + E +++ E F W+ G G+
Sbjct: 58 IMKFSECYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 448 LISSGPK 468
S+G +
Sbjct: 117 AFSNGER 123
>BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 44.0 bits (99), Expect = 3e-04
Identities = 32/133 (24%), Positives = 60/133 (45%), Gaps = 3/133 (2%)
Frame = +1
Query: 112 YPLLGLTTAIWILYR-WQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGY 288
+ +L L + +L+ W+Q+ KL PGP P+PI GN L + D ++ +
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNMLQI---DVKDICKSFTNF 57
Query: 289 AQTFGNVVRVWLGSKLIVFLADADDIE--IILNSHVHIDKATEYKFFKPWLGEGLLISSG 462
++ +G V V+ G IV + ++ +I N + + G G++ S+G
Sbjct: 58 SKVYGPVFTVYFGMNPIVVFHGYESVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNG 117
Query: 463 PKWRSHRKMIAPT 501
+W+ R+ T
Sbjct: 118 KRWKEIRRFSLTT 130
>AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1
protein.
Length = 462
Score = 44.0 bits (99), Expect = 3e-04
Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 2/105 (1%)
Frame = +1
Query: 193 LIPGPAPIPIFGNALTLMRKD-PHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDI- 366
L PGP P+PI GN L K+ P L AQ FG V +++GS+ +V + +
Sbjct: 1 LPPGPFPLPIIGNLFQLELKNIPKSFTRL----AQRFGPVFTLYVGSQRMVVMHGYKAVK 56
Query: 367 EIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPT 501
E +L+ + F G++ ++GP W+ R+ T
Sbjct: 57 EALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWKDIRRFSLTT 101
>M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 43.6 bits (98), Expect = 4e-04
Identities = 34/121 (28%), Positives = 59/121 (48%), Gaps = 3/121 (2%)
Frame = +1
Query: 133 TAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKD-PHELVNLALGYAQTFGNV 309
+ + +L W+Q+S KL PGP P+P+ GN L + KD L NL ++ +G V
Sbjct: 7 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKDISKSLTNL----SKVYGPV 59
Query: 310 VRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWRSHR 483
++ G K IV L + + E +++ + + G G++ S+G KW+ R
Sbjct: 60 FTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIR 119
Query: 484 K 486
+
Sbjct: 120 R 120
>M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 43.6 bits (98), Expect = 4e-04
Identities = 34/121 (28%), Positives = 59/121 (48%), Gaps = 3/121 (2%)
Frame = +1
Query: 133 TAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKD-PHELVNLALGYAQTFGNV 309
+ + +L W+Q+S KL PGP P+P+ GN L + KD L NL ++ +G V
Sbjct: 7 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKDISKSLTNL----SKVYGPV 59
Query: 310 VRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWRSHR 483
++ G K IV L + + E +++ + + G G++ S+G KW+ R
Sbjct: 60 FTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIR 119
Query: 484 K 486
+
Sbjct: 120 R 120
>L16880-1|AAD13466.1| 273|Homo sapiens cytochrome P-450 2C protein.
Length = 273
Score = 43.6 bits (98), Expect = 4e-04
Identities = 34/121 (28%), Positives = 59/121 (48%), Gaps = 3/121 (2%)
Frame = +1
Query: 133 TAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKD-PHELVNLALGYAQTFGNV 309
+ + +L W+Q+S KL PGP P+P+ GN L + KD L NL ++ +G V
Sbjct: 12 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKDISKSLTNL----SKVYGPV 64
Query: 310 VRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWRSHR 483
++ G K IV L + + E +++ + + G G++ S+G KW+ R
Sbjct: 65 FTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIR 124
Query: 484 K 486
+
Sbjct: 125 R 125
>J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein.
Length = 491
Score = 43.6 bits (98), Expect = 4e-04
Identities = 28/101 (27%), Positives = 50/101 (49%), Gaps = 2/101 (1%)
Frame = +1
Query: 190 ELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDI- 366
+L PGP P+ I GN L L +D ++ ++ +G++ V LG + +V L+ +
Sbjct: 29 KLPPGPRPLSILGNLLLLCSQD---MLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVK 85
Query: 367 EIILNSHVHIDKATEY-KFFKPWLGEGLLISSGPKWRSHRK 486
E +++ +Y FF G G+ SSG +W+ R+
Sbjct: 86 EALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQ 126
>EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 491
Score = 43.6 bits (98), Expect = 4e-04
Identities = 28/101 (27%), Positives = 50/101 (49%), Gaps = 2/101 (1%)
Frame = +1
Query: 190 ELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDI- 366
+L PGP P+ I GN L L +D ++ ++ +G++ V LG + +V L+ +
Sbjct: 29 KLPPGPRPLSILGNLLLLCSQD---MLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVK 85
Query: 367 EIILNSHVHIDKATEY-KFFKPWLGEGLLISSGPKWRSHRK 486
E +++ +Y FF G G+ SSG +W+ R+
Sbjct: 86 EALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQ 126
>D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein.
Length = 487
Score = 43.6 bits (98), Expect = 4e-04
Identities = 34/121 (28%), Positives = 59/121 (48%), Gaps = 3/121 (2%)
Frame = +1
Query: 133 TAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKD-PHELVNLALGYAQTFGNV 309
+ + +L W+Q+S KL PGP P+P+ GN L + KD L NL ++ +G V
Sbjct: 9 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKDISKSLTNL----SKVYGPV 61
Query: 310 VRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWRSHR 483
++ G K IV L + + E +++ + + G G++ S+G KW+ R
Sbjct: 62 FTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIR 121
Query: 484 K 486
+
Sbjct: 122 R 122
>BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 43.6 bits (98), Expect = 4e-04
Identities = 34/121 (28%), Positives = 59/121 (48%), Gaps = 3/121 (2%)
Frame = +1
Query: 133 TAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKD-PHELVNLALGYAQTFGNV 309
+ + +L W+Q+S KL PGP P+P+ GN L + KD L NL ++ +G V
Sbjct: 12 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKDISKSLTNL----SKVYGPV 64
Query: 310 VRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWRSHR 483
++ G K IV L + + E +++ + + G G++ S+G KW+ R
Sbjct: 65 FTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIR 124
Query: 484 K 486
+
Sbjct: 125 R 125
>BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein.
Length = 320
Score = 43.6 bits (98), Expect = 4e-04
Identities = 28/101 (27%), Positives = 50/101 (49%), Gaps = 2/101 (1%)
Frame = +1
Query: 190 ELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDI- 366
+L PGP P+ I GN L L +D ++ ++ +G++ V LG + +V L+ +
Sbjct: 29 KLPPGPRPLSILGNLLLLCSQD---MLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVK 85
Query: 367 EIILNSHVHIDKATEY-KFFKPWLGEGLLISSGPKWRSHRK 486
E +++ +Y FF G G+ SSG +W+ R+
Sbjct: 86 EALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQ 126
>BC070317-1|AAH70317.1| 162|Homo sapiens CYP2C9 protein protein.
Length = 162
Score = 43.6 bits (98), Expect = 4e-04
Identities = 34/121 (28%), Positives = 59/121 (48%), Gaps = 3/121 (2%)
Frame = +1
Query: 133 TAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKD-PHELVNLALGYAQTFGNV 309
+ + +L W+Q+S KL PGP P+P+ GN L + KD L NL ++ +G V
Sbjct: 12 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKDISKSLTNL----SKVYGPV 64
Query: 310 VRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWRSHR 483
++ G K IV L + + E +++ + + G G++ S+G KW+ R
Sbjct: 65 FTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIR 124
Query: 484 K 486
+
Sbjct: 125 R 125
>BC020754-1|AAH20754.1| 162|Homo sapiens CYP2C9 protein protein.
Length = 162
Score = 43.6 bits (98), Expect = 4e-04
Identities = 34/121 (28%), Positives = 59/121 (48%), Gaps = 3/121 (2%)
Frame = +1
Query: 133 TAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKD-PHELVNLALGYAQTFGNV 309
+ + +L W+Q+S KL PGP P+P+ GN L + KD L NL ++ +G V
Sbjct: 12 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKDISKSLTNL----SKVYGPV 64
Query: 310 VRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWRSHR 483
++ G K IV L + + E +++ + + G G++ S+G KW+ R
Sbjct: 65 FTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIR 124
Query: 484 K 486
+
Sbjct: 125 R 125
>AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 43.6 bits (98), Expect = 4e-04
Identities = 34/121 (28%), Positives = 59/121 (48%), Gaps = 3/121 (2%)
Frame = +1
Query: 133 TAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKD-PHELVNLALGYAQTFGNV 309
+ + +L W+Q+S KL PGP P+P+ GN L + KD L NL ++ +G V
Sbjct: 12 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKDISKSLTNL----SKVYGPV 64
Query: 310 VRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWRSHR 483
++ G K IV L + + E +++ + + G G++ S+G KW+ R
Sbjct: 65 FTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIR 124
Query: 484 K 486
+
Sbjct: 125 R 125
>AY513607-1|AAR90938.1| 100|Homo sapiens truncated cytochrome P450
2A13 variant 4 protein.
Length = 100
Score = 43.6 bits (98), Expect = 4e-04
Identities = 29/106 (27%), Positives = 51/106 (48%)
Frame = +1
Query: 97 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNL 276
S ++ LL T + ++ W+Q KL PGP P+P GN L L + ++ N
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 277 ALGYAQTFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEY 414
+ ++ +G V + LG + +V L D ++ L +D+A E+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVKEAL-----VDQAEEF 98
>AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 43.6 bits (98), Expect = 4e-04
Identities = 34/121 (28%), Positives = 59/121 (48%), Gaps = 3/121 (2%)
Frame = +1
Query: 133 TAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKD-PHELVNLALGYAQTFGNV 309
+ + +L W+Q+S KL PGP P+P+ GN L + KD L NL ++ +G V
Sbjct: 12 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKDISKSLTNL----SKVYGPV 64
Query: 310 VRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWRSHR 483
++ G K IV L + + E +++ + + G G++ S+G KW+ R
Sbjct: 65 FTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIR 124
Query: 484 K 486
+
Sbjct: 125 R 125
>AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 43.6 bits (98), Expect = 4e-04
Identities = 34/121 (28%), Positives = 59/121 (48%), Gaps = 3/121 (2%)
Frame = +1
Query: 133 TAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKD-PHELVNLALGYAQTFGNV 309
+ + +L W+Q+S KL PGP P+P+ GN L + KD L NL ++ +G V
Sbjct: 12 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKDISKSLTNL----SKVYGPV 64
Query: 310 VRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWRSHR 483
++ G K IV L + + E +++ + + G G++ S+G KW+ R
Sbjct: 65 FTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIR 124
Query: 484 K 486
+
Sbjct: 125 R 125
>AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1
protein.
Length = 495
Score = 43.6 bits (98), Expect = 4e-04
Identities = 28/101 (27%), Positives = 50/101 (49%), Gaps = 2/101 (1%)
Frame = +1
Query: 190 ELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDI- 366
+L PGP P+ I GN L L +D ++ ++ +G++ V LG + +V L+ +
Sbjct: 29 KLPPGPRPLSILGNLLLLCSQD---MLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVK 85
Query: 367 EIILNSHVHIDKATEY-KFFKPWLGEGLLISSGPKWRSHRK 486
E +++ +Y FF G G+ SSG +W+ R+
Sbjct: 86 EALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQ 126
>Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein.
Length = 490
Score = 43.2 bits (97), Expect = 6e-04
Identities = 32/133 (24%), Positives = 60/133 (45%), Gaps = 3/133 (2%)
Frame = +1
Query: 112 YPLLGLTTAIWILYR-WQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGY 288
+ +L L + +L+ W+Q+ KL PGP P+PI GN L + D ++ +
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNMLQI---DVKDICKSFTNF 57
Query: 289 AQTFGNVVRVWLGSKLIVFLADADDIE--IILNSHVHIDKATEYKFFKPWLGEGLLISSG 462
++ +G V V+ G IV + ++ +I N + + G G++ S+G
Sbjct: 58 SKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNG 117
Query: 463 PKWRSHRKMIAPT 501
+W+ R+ T
Sbjct: 118 KRWKEIRRFSLTT 130
>S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein.
Length = 477
Score = 43.2 bits (97), Expect = 6e-04
Identities = 34/117 (29%), Positives = 57/117 (48%), Gaps = 3/117 (2%)
Frame = +1
Query: 145 ILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKD-PHELVNLALGYAQTFGNVVRVW 321
+L W+Q+S KL PGP P+P+ GN L + KD L NL ++ +G V ++
Sbjct: 3 LLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKDISKSLTNL----SKVYGPVFTLY 55
Query: 322 LGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWRSHRK 486
G K IV L + + E +++ + + G G++ S+G KW+ R+
Sbjct: 56 FGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRR 112
>AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 43.2 bits (97), Expect = 6e-04
Identities = 32/133 (24%), Positives = 60/133 (45%), Gaps = 3/133 (2%)
Frame = +1
Query: 112 YPLLGLTTAIWILYR-WQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGY 288
+ +L L + +L+ W+Q+ KL PGP P+PI GN L + D ++ +
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNMLQI---DVKDICKSFTNF 57
Query: 289 AQTFGNVVRVWLGSKLIVFLADADDIE--IILNSHVHIDKATEYKFFKPWLGEGLLISSG 462
++ +G V V+ G IV + ++ +I N + + G G++ S+G
Sbjct: 58 SKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNG 117
Query: 463 PKWRSHRKMIAPT 501
+W+ R+ T
Sbjct: 118 KRWKEIRRFSLTT 130
>AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 43.2 bits (97), Expect = 6e-04
Identities = 32/133 (24%), Positives = 60/133 (45%), Gaps = 3/133 (2%)
Frame = +1
Query: 112 YPLLGLTTAIWILYR-WQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGY 288
+ +L L + +L+ W+Q+ KL PGP P+PI GN L + D ++ +
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNMLQI---DVKDICKSFTNF 57
Query: 289 AQTFGNVVRVWLGSKLIVFLADADDIE--IILNSHVHIDKATEYKFFKPWLGEGLLISSG 462
++ +G V V+ G IV + ++ +I N + + G G++ S+G
Sbjct: 58 SKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNG 117
Query: 463 PKWRSHRKMIAPT 501
+W+ R+ T
Sbjct: 118 KRWKEIRRFSLTT 130
>M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrome
P-450 1 mRNA, complete cds, clone Hp1-2. ).
Length = 393
Score = 42.7 bits (96), Expect = 7e-04
Identities = 31/128 (24%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
Frame = +1
Query: 112 YPLLGLTTAIWILYR-WQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGY 288
+ +L L + +L+ W+Q+ KL PGP P+PI GN L + D ++ +
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNMLQI---DVKDICKSFTNF 57
Query: 289 AQTFGNVVRVWLGSKLIVFLADADDIE--IILNSHVHIDKATEYKFFKPWLGEGLLISSG 462
++ +G V V+ G IV + ++ +I N + + G G++ S+G
Sbjct: 58 SKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNG 117
Query: 463 PKWRSHRK 486
+W+ R+
Sbjct: 118 KRWKEIRR 125
>M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrome
P-450 1 functional form mRNA, complete cds. ).
Length = 490
Score = 42.7 bits (96), Expect = 7e-04
Identities = 31/128 (24%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
Frame = +1
Query: 112 YPLLGLTTAIWILYR-WQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGY 288
+ +L L + +L+ W+Q+ KL PGP P+PI GN L + D ++ +
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNMLQI---DVKDICKSFTNF 57
Query: 289 AQTFGNVVRVWLGSKLIVFLADADDIE--IILNSHVHIDKATEYKFFKPWLGEGLLISSG 462
++ +G V V+ G IV + ++ +I N + + G G++ S+G
Sbjct: 58 SKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNG 117
Query: 463 PKWRSHRK 486
+W+ R+
Sbjct: 118 KRWKEIRR 125
>BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 7 protein.
Length = 494
Score = 42.7 bits (96), Expect = 7e-04
Identities = 33/127 (25%), Positives = 57/127 (44%), Gaps = 3/127 (2%)
Frame = +1
Query: 97 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNL 276
S ++ LL T + ++ WQQ KL PGP P+P GN L L + + +
Sbjct: 4 SGLLLVALLACLTVMVLMSVWQQRKSRGKLP---PGPTPLPFIGNYLQL---NTEHICDS 57
Query: 277 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 447
+ +++ +G V + LG + V L D + E +++ E F W+ G G+
Sbjct: 58 IMKFSECYGPVFTIHLGPRRAVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 448 LISSGPK 468
S+G +
Sbjct: 117 AFSNGER 123
>M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein.
Length = 480
Score = 42.3 bits (95), Expect = 0.001
Identities = 29/117 (24%), Positives = 52/117 (44%), Gaps = 2/117 (1%)
Frame = +1
Query: 157 WQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWLGSKL 336
W+Q+ KL PGP P+PI GN L + D ++ +++ +G V V+ G
Sbjct: 10 WRQSCRRRKLP---PGPTPLPIIGNMLQI---DVKDICKSFTNFSKVYGPVFTVYFGMNP 63
Query: 337 IVFLADADDIE--IILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPT 501
IV + ++ +I N + + G G++ S+G +W+ R+ T
Sbjct: 64 IVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTT 120
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 41.9 bits (94), Expect = 0.001
Identities = 32/130 (24%), Positives = 62/130 (47%), Gaps = 4/130 (3%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSH--MHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTF 300
L ++ +LY + +SH KL IPGP P+P GN L+ + + + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHK----GFCMFDMECHKKY 68
Query: 301 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 474
G V + G + ++ + D D I+++L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKLVLVKECY-SVFTNREPFGPVGFMKSAISIAEDEEWK 127
Query: 475 SHRKMIAPTF 504
R +++PTF
Sbjct: 128 RLRSLLSPTF 137
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 41.9 bits (94), Expect = 0.001
Identities = 32/130 (24%), Positives = 61/130 (46%), Gaps = 4/130 (3%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSH--MHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTF 300
L ++ +LY + +SH KL IPGP P+P GN L+ + + + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHK----GFCMFDMECHKKY 68
Query: 301 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 474
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVCGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 475 SHRKMIAPTF 504
R +++PTF
Sbjct: 128 RLRSLLSPTF 137
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 41.9 bits (94), Expect = 0.001
Identities = 32/130 (24%), Positives = 62/130 (47%), Gaps = 4/130 (3%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSH--MHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTF 300
L ++ +LY + +SH KL IPGP P+P GN L+ + + + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHK----GFCMFDMECHKKY 68
Query: 301 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 474
G V + G + ++ + D D I+++L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKLVLVKECY-SVFTNREPFGPVGFMKSAISIAEDEEWK 127
Query: 475 SHRKMIAPTF 504
R +++PTF
Sbjct: 128 RLRSLLSPTF 137
>AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P450
4B1 variant protein.
Length = 497
Score = 41.5 bits (93), Expect = 0.002
Identities = 38/133 (28%), Positives = 57/133 (42%)
Frame = +1
Query: 118 LLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQT 297
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 298 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 477
F +W G + I FL +I + K G GLL+ GPKW
Sbjct: 77 FPYAHPLWFG-QFIGFL--------------NIYEPDYAKAVYSRGGRGLLVLEGPKWLQ 121
Query: 478 HRKMIAPTFHINI 516
HRK++ P FH ++
Sbjct: 122 HRKLLTPGFHYDV 134
>AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 41.5 bits (93), Expect = 0.002
Identities = 38/133 (28%), Positives = 57/133 (42%)
Frame = +1
Query: 118 LLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQT 297
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 298 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 477
F +W G + I FL +I + K G GLL+ GPKW
Sbjct: 77 FPYAHPLWFG-QFIGFL--------------NIYEPDYAKAVYSRGGRGLLVLEGPKWLQ 121
Query: 478 HRKMIAPTFHINI 516
HRK++ P FH ++
Sbjct: 122 HRKLLTPGFHYDV 134
>AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 41.5 bits (93), Expect = 0.002
Identities = 38/133 (28%), Positives = 57/133 (42%)
Frame = +1
Query: 118 LLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQT 297
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 298 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 477
F +W G + I FL +I + K G GLL+ GPKW
Sbjct: 77 FPYAHPLWFG-QFIGFL--------------NIYEPDYAKAVYSRGGRGLLVLEGPKWLQ 121
Query: 478 HRKMIAPTFHINI 516
HRK++ P FH ++
Sbjct: 122 HRKLLTPGFHYDV 134
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 41.5 bits (93), Expect = 0.002
Identities = 32/130 (24%), Positives = 62/130 (47%), Gaps = 4/130 (3%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSH--MHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTF 300
+ T++ +LY + +SH KL IPGP P+P GN L+ + + + +
Sbjct: 15 VATSLVLLYIYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHK----GFCMFDMECHKKY 68
Query: 301 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 474
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 475 SHRKMIAPTF 504
R +++PTF
Sbjct: 128 RLRSLLSPTF 137
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 41.1 bits (92), Expect = 0.002
Identities = 32/130 (24%), Positives = 61/130 (46%), Gaps = 4/130 (3%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSH--MHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTF 300
L ++ +LY + +SH KL IPGP P+P GN L+ + + + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHK----GFCMFDMECHKKY 68
Query: 301 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 474
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 475 SHRKMIAPTF 504
R +++PTF
Sbjct: 128 RLRSLLSPTF 137
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 41.1 bits (92), Expect = 0.002
Identities = 32/130 (24%), Positives = 61/130 (46%), Gaps = 4/130 (3%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSH--MHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTF 300
L ++ +LY + +SH KL IPGP P+P GN L+ + + + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHK----GFCMFDMECHKKY 68
Query: 301 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 474
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 475 SHRKMIAPTF 504
R +++PTF
Sbjct: 128 RLRSLLSPTF 137
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 41.1 bits (92), Expect = 0.002
Identities = 32/130 (24%), Positives = 61/130 (46%), Gaps = 4/130 (3%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSH--MHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTF 300
L ++ +LY + +SH KL IPGP P+P GN L+ + + + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHK----GFCMFDMECHKKY 68
Query: 301 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 474
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 475 SHRKMIAPTF 504
R +++PTF
Sbjct: 128 RLRSLLSPTF 137
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.002
Identities = 32/130 (24%), Positives = 61/130 (46%), Gaps = 4/130 (3%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSH--MHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTF 300
L ++ +LY + +SH KL IPGP P+P GN L+ + + + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHK----GFCMFDMECHKKY 68
Query: 301 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 474
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 475 SHRKMIAPTF 504
R +++PTF
Sbjct: 128 RLRSLLSPTF 137
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.002
Identities = 32/130 (24%), Positives = 61/130 (46%), Gaps = 4/130 (3%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSH--MHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTF 300
L ++ +LY + +SH KL IPGP P+P GN L+ + + + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHK----GFCMFDMECHKKY 68
Query: 301 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 474
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 475 SHRKMIAPTF 504
R +++PTF
Sbjct: 128 RLRSLLSPTF 137
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.002
Identities = 32/130 (24%), Positives = 61/130 (46%), Gaps = 4/130 (3%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSH--MHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTF 300
L ++ +LY + +SH KL IPGP P+P GN L+ + + + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHK----GFCMFDMECHKKY 68
Query: 301 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 474
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 475 SHRKMIAPTF 504
R +++PTF
Sbjct: 128 RLRSLLSPTF 137
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.002
Identities = 32/130 (24%), Positives = 61/130 (46%), Gaps = 4/130 (3%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSH--MHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTF 300
L ++ +LY + +SH KL IPGP P+P GN L+ + + + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHK----GFCMFDMECHKKY 68
Query: 301 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 474
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 475 SHRKMIAPTF 504
R +++PTF
Sbjct: 128 RLRSLLSPTF 137
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.002
Identities = 32/130 (24%), Positives = 61/130 (46%), Gaps = 4/130 (3%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSH--MHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTF 300
L ++ +LY + +SH KL IPGP P+P GN L+ + + + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHK----GFCMFDMECHKKY 68
Query: 301 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 474
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 475 SHRKMIAPTF 504
R +++PTF
Sbjct: 128 RLRSLLSPTF 137
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.002
Identities = 32/130 (24%), Positives = 61/130 (46%), Gaps = 4/130 (3%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSH--MHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTF 300
L ++ +LY + +SH KL IPGP P+P GN L+ + + + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHK----GFCMFDMECHKKY 68
Query: 301 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 474
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 475 SHRKMIAPTF 504
R +++PTF
Sbjct: 128 RLRSLLSPTF 137
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.002
Identities = 32/130 (24%), Positives = 61/130 (46%), Gaps = 4/130 (3%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSH--MHKLAELIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTF 300
L ++ +LY + +SH KL IPGP P+P GN L+ + + + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHK----GFCMFDMECHKKY 68
Query: 301 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 474
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 475 SHRKMIAPTF 504
R +++PTF
Sbjct: 128 RLRSLLSPTF 137
>M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 40.7 bits (91), Expect = 0.003
Identities = 33/129 (25%), Positives = 62/129 (48%), Gaps = 3/129 (2%)
Frame = +1
Query: 109 FYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKD-PHELVNLALG 285
F L+ + + +L W+Q+S KL PGP P+P+ GN L + KD L NL
Sbjct: 4 FVVLVLCLSCLLLLSIWRQSSGRGKLP---PGPTPLPVIGNILQIDIKDVSKSLTNL--- 57
Query: 286 YAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISS 459
++ +G V ++ G + +V L + + E +++ + + G G++ S+
Sbjct: 58 -SKIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSN 116
Query: 460 GPKWRSHRK 486
G +W+ R+
Sbjct: 117 GKRWKEIRR 125
>L39098-1|AAL31347.1| 160|Homo sapiens S-mephenytoin 4-hydroxylase
protein.
Length = 160
Score = 40.7 bits (91), Expect = 0.003
Identities = 33/129 (25%), Positives = 62/129 (48%), Gaps = 3/129 (2%)
Frame = +1
Query: 109 FYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKD-PHELVNLALG 285
F L+ + + +L W+Q+S KL PGP P+P+ GN L + KD L NL
Sbjct: 4 FVVLVLCLSCLLLLSIWRQSSGRGKLP---PGPTPLPVIGNILQIDIKDVSKSLTNL--- 57
Query: 286 YAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISS 459
++ +G V ++ G + +V L + + E +++ + + G G++ S+
Sbjct: 58 -SKIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSN 116
Query: 460 GPKWRSHRK 486
G +W+ R+
Sbjct: 117 GKRWKEIRR 125
>BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family 2,
subfamily S, polypeptide 1 protein.
Length = 504
Score = 40.7 bits (91), Expect = 0.003
Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 3/101 (2%)
Frame = +1
Query: 193 LIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWLGS-KLIVFLADADDIE 369
L PGP P+P+ GN L L P L + + ++ +G V ++LG + +V L + +
Sbjct: 32 LPPGPTPLPLLGNLLQLR---PGALYSGLMRLSKKYGPVFTIYLGPWRPVVVLVGQEAVR 88
Query: 370 IILNSHVH--IDKATEYKFFKPWLGEGLLISSGPKWRSHRK 486
L + T + G G+ S+G +WR RK
Sbjct: 89 EALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRK 129
>AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 40.7 bits (91), Expect = 0.003
Identities = 33/129 (25%), Positives = 62/129 (48%), Gaps = 3/129 (2%)
Frame = +1
Query: 109 FYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKD-PHELVNLALG 285
F L+ + + +L W+Q+S KL PGP P+P+ GN L + KD L NL
Sbjct: 4 FVVLVLCLSCLLLLSIWRQSSGRGKLP---PGPTPLPVIGNILQIDIKDVSKSLTNL--- 57
Query: 286 YAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISS 459
++ +G V ++ G + +V L + + E +++ + + G G++ S+
Sbjct: 58 -SKIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSN 116
Query: 460 GPKWRSHRK 486
G +W+ R+
Sbjct: 117 GKRWKEIRR 125
>AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein.
Length = 504
Score = 40.7 bits (91), Expect = 0.003
Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 3/101 (2%)
Frame = +1
Query: 193 LIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWLGS-KLIVFLADADDIE 369
L PGP P+P+ GN L L P L + + ++ +G V ++LG + +V L + +
Sbjct: 32 LPPGPTPLPLLGNLLQLR---PGALYSGLMRLSKKYGPVFTIYLGPWRPVVVLVGQEAVR 88
Query: 370 IILNSHVH--IDKATEYKFFKPWLGEGLLISSGPKWRSHRK 486
L + T + G G+ S+G +WR RK
Sbjct: 89 EALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRK 129
>AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 40.7 bits (91), Expect = 0.003
Identities = 33/129 (25%), Positives = 62/129 (48%), Gaps = 3/129 (2%)
Frame = +1
Query: 109 FYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKD-PHELVNLALG 285
F L+ + + +L W+Q+S KL PGP P+P+ GN L + KD L NL
Sbjct: 4 FVVLVLCLSCLLLLSIWRQSSGRGKLP---PGPTPLPVIGNILQIDIKDVSKSLTNL--- 57
Query: 286 YAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISS 459
++ +G V ++ G + +V L + + E +++ + + G G++ S+
Sbjct: 58 -SKIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSN 116
Query: 460 GPKWRSHRK 486
G +W+ R+
Sbjct: 117 GKRWKEIRR 125
>AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 40.7 bits (91), Expect = 0.003
Identities = 33/129 (25%), Positives = 62/129 (48%), Gaps = 3/129 (2%)
Frame = +1
Query: 109 FYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKD-PHELVNLALG 285
F L+ + + +L W+Q+S KL PGP P+P+ GN L + KD L NL
Sbjct: 4 FVVLVLCLSCLLLLSIWRQSSGRGKLP---PGPTPLPVIGNILQIDIKDVSKSLTNL--- 57
Query: 286 YAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISS 459
++ +G V ++ G + +V L + + E +++ + + G G++ S+
Sbjct: 58 -SKIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSN 116
Query: 460 GPKWRSHRK 486
G +W+ R+
Sbjct: 117 GKRWKEIRR 125
>AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens
cDNA FLJ14699 fis, clone NT2RP2006571, moderately
similar to CYTOCHROME P450 2G1 (EC 1.14.14.1). ).
Length = 564
Score = 40.7 bits (91), Expect = 0.003
Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 3/101 (2%)
Frame = +1
Query: 193 LIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWLGS-KLIVFLADADDIE 369
L PGP P+P+ GN L L P L + + ++ +G V ++LG + +V L + +
Sbjct: 32 LPPGPTPLPLLGNLLQLR---PGALYSGLMRLSKKYGPVFTIYLGPWRPVVVLVGQEAVR 88
Query: 370 IILNSHVH--IDKATEYKFFKPWLGEGLLISSGPKWRSHRK 486
L + T + G G+ S+G +WR RK
Sbjct: 89 EALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRK 129
>AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1
protein.
Length = 504
Score = 40.7 bits (91), Expect = 0.003
Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 3/101 (2%)
Frame = +1
Query: 193 LIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWLGS-KLIVFLADADDIE 369
L PGP P+P+ GN L L P L + + ++ +G V ++LG + +V L + +
Sbjct: 32 LPPGPTPLPLLGNLLQLR---PGALYSGLMRLSKKYGPVFTIYLGPWRPVVVLVGQEAVR 88
Query: 370 IILNSHVH--IDKATEYKFFKPWLGEGLLISSGPKWRSHRK 486
L + T + G G+ S+G +WR RK
Sbjct: 89 EALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRK 129
>AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 40.3 bits (90), Expect = 0.004
Identities = 32/102 (31%), Positives = 52/102 (50%), Gaps = 5/102 (4%)
Frame = +1
Query: 199 PGPAPIPIFGNALTLMRKDPHELVNLALG-YAQTFGNVVRVWLGSKLIVFLADADDIE-- 369
PGP P+ G+ LTL K+PH LAL +Q +G+V+++ +GS +V L+ D I
Sbjct: 41 PGPWDWPLIGHMLTL-GKNPH----LALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQA 95
Query: 370 IILNSHVHIDKATEYKFFKPWLGEGLLIS--SGPKWRSHRKM 489
++ + Y F G+ + S SGP W + R++
Sbjct: 96 LVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRL 137
>AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 40.3 bits (90), Expect = 0.004
Identities = 32/102 (31%), Positives = 52/102 (50%), Gaps = 5/102 (4%)
Frame = +1
Query: 199 PGPAPIPIFGNALTLMRKDPHELVNLALG-YAQTFGNVVRVWLGSKLIVFLADADDIE-- 369
PGP P+ G+ LTL K+PH LAL +Q +G+V+++ +GS +V L+ D I
Sbjct: 41 PGPWDWPLIGHMLTL-GKNPH----LALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQA 95
Query: 370 IILNSHVHIDKATEYKFFKPWLGEGLLIS--SGPKWRSHRKM 489
++ + Y F G+ + S SGP W + R++
Sbjct: 96 LVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRL 137
>M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein.
Length = 462
Score = 39.1 bits (87), Expect = 0.009
Identities = 26/105 (24%), Positives = 47/105 (44%), Gaps = 2/105 (1%)
Frame = +1
Query: 193 LIPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDIE- 369
L PGP P+PI GN L + D ++ +++ +G V V+ G IV + ++
Sbjct: 1 LPPGPTPLPIIGNMLQI---DVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKE 57
Query: 370 -IILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPT 501
+I N + + G G++ S+G +W+ R+ T
Sbjct: 58 ALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTT 102
>BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family 2,
subfamily W, polypeptide 1 protein.
Length = 490
Score = 38.7 bits (86), Expect = 0.012
Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 2/105 (1%)
Frame = +1
Query: 199 PGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDIEIIL 378
PGP P+P+ GN L L+R + + L ++ +G V V LG + V L + ++ L
Sbjct: 33 PGPRPLPLVGN-LHLLRLSQQDRSLMEL--SERYGPVFTVHLGRQKTVVLTGFEAVKEAL 89
Query: 379 NSHVH--IDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFH 507
D+ F G G+ SSG +WR+ R+ H
Sbjct: 90 AGPGQELADRPPIAIFQLIQRGGGIFFSSGARWRAARQFTVRALH 134
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 38.7 bits (86), Expect = 0.012
Identities = 32/130 (24%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSHMHKLAEL--IPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTF 300
+ T++ +LY + +H HKL + IPGP P+P G L +R L N + +
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLR----GLWNFDRECNEKY 68
Query: 301 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 474
G + ++ G + ++ + D D I+ +L + T P +L L + +W+
Sbjct: 69 GEMWGLYEGQQPMLVIMDPDMIKTVLVKECY-SVFTNQMPLGPMGFLKSALSFAEDEEWK 127
Query: 475 SHRKMIAPTF 504
R +++P F
Sbjct: 128 RIRTLLSPAF 137
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 38.7 bits (86), Expect = 0.012
Identities = 32/130 (24%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSHMHKLAEL--IPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTF 300
+ T++ +LY + +H HKL + IPGP P+P G L +R L N + +
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLR----GLWNFDRECNEKY 68
Query: 301 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 474
G + ++ G + ++ + D D I+ +L + T P +L L + +W+
Sbjct: 69 GEMWGLYEGQQPMLVIMDPDMIKTVLVKECY-SVFTNQMPLGPMGFLKSALSFAEDEEWK 127
Query: 475 SHRKMIAPTF 504
R +++P F
Sbjct: 128 RIRTLLSPAF 137
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 38.7 bits (86), Expect = 0.012
Identities = 32/130 (24%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSHMHKLAEL--IPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTF 300
+ T++ +LY + +H HKL + IPGP P+P G L +R L N + +
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLR----GLWNFDRECNEKY 68
Query: 301 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 474
G + ++ G + ++ + D D I+ +L + T P +L L + +W+
Sbjct: 69 GEMWGLYEGQQPMLVIMDPDMIKTVLVKECY-SVFTNQMPLGPMGFLKSALSFAEDEEWK 127
Query: 475 SHRKMIAPTF 504
R +++P F
Sbjct: 128 RIRTLLSPAF 137
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 38.7 bits (86), Expect = 0.012
Identities = 32/130 (24%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSHMHKLAEL--IPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTF 300
+ T++ +LY + +H HKL + IPGP P+P G L +R L N + +
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLR----GLWNFDRECNEKY 68
Query: 301 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 474
G + ++ G + ++ + D D I+ +L + T P +L L + +W+
Sbjct: 69 GEMWGLYEGQQPMLVIMDPDMIKTVLVKECY-SVFTNQMPLGPMGFLKSALSFAEDEEWK 127
Query: 475 SHRKMIAPTF 504
R +++P F
Sbjct: 128 RIRTLLSPAF 137
>AF280111-1|AAG33012.1| 250|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 250
Score = 38.7 bits (86), Expect = 0.012
Identities = 32/130 (24%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSHMHKLAEL--IPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTF 300
+ T++ +LY + +H HKL + IPGP P+P G L +R L N + +
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLR----GLWNFDRECNEKY 68
Query: 301 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 474
G + ++ G + ++ + D D I+ +L + T P +L L + +W+
Sbjct: 69 GEMWGLYEGQQPMLVIMDPDMIKTVLVKECY-SVFTNQMPLGPMGFLKSALSFAEDEEWK 127
Query: 475 SHRKMIAPTF 504
R +++P F
Sbjct: 128 RIRTLLSPAF 137
>AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 420
Score = 38.7 bits (86), Expect = 0.012
Identities = 32/130 (24%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSHMHKLAEL--IPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTF 300
+ T++ +LY + +H HKL + IPGP P+P G L +R L N + +
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLR----GLWNFDRECNEKY 68
Query: 301 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 474
G + ++ G + ++ + D D I+ +L + T P +L L + +W+
Sbjct: 69 GEMWGLYEGQQPMLVIMDPDMIKTVLVKECY-SVFTNQMPLGPMGFLKSALSFAEDEEWK 127
Query: 475 SHRKMIAPTF 504
R +++P F
Sbjct: 128 RIRTLLSPAF 137
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 38.7 bits (86), Expect = 0.012
Identities = 32/130 (24%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSHMHKLAEL--IPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTF 300
+ T++ +LY + +H HKL + IPGP P+P G L +R L N + +
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLR----GLWNFDRECNEKY 68
Query: 301 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 474
G + ++ G + ++ + D D I+ +L + T P +L L + +W+
Sbjct: 69 GEMWGLYEGQQPMLVIMDPDMIKTVLVKECY-SVFTNQMPLGPMGFLKSALSFAEDEEWK 127
Query: 475 SHRKMIAPTF 504
R +++P F
Sbjct: 128 RIRTLLSPAF 137
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 38.7 bits (86), Expect = 0.012
Identities = 32/130 (24%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSHMHKLAEL--IPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTF 300
+ T++ +LY + +H HKL + IPGP P+P G L +R L N + +
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLR----GLWNFDRECNEKY 68
Query: 301 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 474
G + ++ G + ++ + D D I+ +L + T P +L L + +W+
Sbjct: 69 GEMWGLYEGQQPMLVIMDPDMIKTVLVKECY-SVFTNQMPLGPMGFLKSALSFAEDEEWK 127
Query: 475 SHRKMIAPTF 504
R +++P F
Sbjct: 128 RIRTLLSPAF 137
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 38.7 bits (86), Expect = 0.012
Identities = 32/130 (24%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSHMHKLAEL--IPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTF 300
+ T++ +LY + +H HKL + IPGP P+P G L +R L N + +
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLR----GLWNFDRECNEKY 68
Query: 301 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 474
G + ++ G + ++ + D D I+ +L + T P +L L + +W+
Sbjct: 69 GEMWGLYEGQQPMLVIMDPDMIKTVLVKECY-SVFTNQMPLGPMGFLKSALSFAEDEEWK 127
Query: 475 SHRKMIAPTF 504
R +++P F
Sbjct: 128 RIRTLLSPAF 137
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 38.7 bits (86), Expect = 0.012
Identities = 32/130 (24%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSHMHKLAEL--IPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTF 300
+ T++ +LY + +H HKL + IPGP P+P G L +R L N + +
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLR----GLWNFDRECNEKY 68
Query: 301 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 474
G + ++ G + ++ + D D I+ +L + T P +L L + +W+
Sbjct: 69 GEMWGLYEGQQPMLVIMDPDMIKTVLVKECY-SVFTNQMPLGPMGFLKSALSFAEDEEWK 127
Query: 475 SHRKMIAPTF 504
R +++P F
Sbjct: 128 RIRTLLSPAF 137
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 37.9 bits (84), Expect = 0.021
Identities = 33/139 (23%), Positives = 64/139 (46%), Gaps = 2/139 (1%)
Frame = +1
Query: 94 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVN 273
N V + LL ++ + LY + + KL IPGP P+P GNAL+ + +
Sbjct: 6 NLAVETWLLLAVSLILLYLYGTRTHGLFKKLG--IPGPTPLPFLGNALSFRKGYWTFDME 63
Query: 274 LALGYAQTFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGL 447
Y + +G ++ + ++ + D D I+ +L + T + F P ++ +
Sbjct: 64 CYKKYRKVWG----IYDCQQPMLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAI 118
Query: 448 LISSGPKWRSHRKMIAPTF 504
I+ +W+ R +++PTF
Sbjct: 119 SIAEDEEWKRIRSLLSPTF 137
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 37.9 bits (84), Expect = 0.021
Identities = 33/139 (23%), Positives = 64/139 (46%), Gaps = 2/139 (1%)
Frame = +1
Query: 94 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVN 273
N V + LL ++ + LY + + KL IPGP P+P GNAL+ + +
Sbjct: 6 NLAVETWLLLAVSLILLYLYGTRTHGLFKKLG--IPGPTPLPFLGNALSFRKGYWTFDME 63
Query: 274 LALGYAQTFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGL 447
Y + +G ++ + ++ + D D I+ +L + T + F P ++ +
Sbjct: 64 CYKKYRKVWG----IYDCQQPMLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAI 118
Query: 448 LISSGPKWRSHRKMIAPTF 504
I+ +W+ R +++PTF
Sbjct: 119 SIAEDEEWKRIRSLLSPTF 137
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 37.9 bits (84), Expect = 0.021
Identities = 33/139 (23%), Positives = 64/139 (46%), Gaps = 2/139 (1%)
Frame = +1
Query: 94 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVN 273
N V + LL ++ + LY + + KL IPGP P+P GNAL+ + +
Sbjct: 6 NLAVETWLLLAVSLILLYLYGTRTHGLFKKLG--IPGPTPLPFLGNALSFRKGYWTFDME 63
Query: 274 LALGYAQTFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGL 447
Y + +G ++ + ++ + D D I+ +L + T + F P ++ +
Sbjct: 64 CYKKYRKVWG----IYDCQQPMLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAI 118
Query: 448 LISSGPKWRSHRKMIAPTF 504
I+ +W+ R +++PTF
Sbjct: 119 SIAEDEEWKRIRSLLSPTF 137
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 37.9 bits (84), Expect = 0.021
Identities = 33/139 (23%), Positives = 64/139 (46%), Gaps = 2/139 (1%)
Frame = +1
Query: 94 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVN 273
N V + LL ++ + LY + + KL IPGP P+P GNAL+ + +
Sbjct: 6 NLAVETWLLLAVSLILLYLYGTRTHGLFKKLG--IPGPTPLPFLGNALSFRKGYWTFDME 63
Query: 274 LALGYAQTFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGL 447
Y + +G ++ + ++ + D D I+ +L + T + F P ++ +
Sbjct: 64 CYKKYRKVWG----IYDCQQPMLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAI 118
Query: 448 LISSGPKWRSHRKMIAPTF 504
I+ +W+ R +++PTF
Sbjct: 119 SIAEDEEWKRIRSLLSPTF 137
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 37.1 bits (82), Expect = 0.036
Identities = 30/139 (21%), Positives = 61/139 (43%), Gaps = 2/139 (1%)
Frame = +1
Query: 94 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVN 273
N V + LL ++ + LY + + +L IPGP P+P+ GN L+ + L
Sbjct: 6 NLAVETWLLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVLSYRQ----GLWK 59
Query: 274 LALGYAQTFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGL 447
+ +G + + G ++ + D D I +L + T + P ++ +
Sbjct: 60 FDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECY-SVFTNRRSLGPVGFMKSAI 118
Query: 448 LISSGPKWRSHRKMIAPTF 504
++ +W+ R +++PTF
Sbjct: 119 SLAEDEEWKRIRSLLSPTF 137
>DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P450,
family 3, subfamily A, polypeptide 5 protein.
Length = 347
Score = 37.1 bits (82), Expect = 0.036
Identities = 30/139 (21%), Positives = 61/139 (43%), Gaps = 2/139 (1%)
Frame = +1
Query: 94 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVN 273
N V + LL ++ + LY + + +L IPGP P+P+ GN L+ + L
Sbjct: 6 NLAVETWLLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVLSYRQ----GLWK 59
Query: 274 LALGYAQTFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGL 447
+ +G + + G ++ + D D I +L + T + P ++ +
Sbjct: 60 FDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECY-SVFTNRRSLGPVGFMKSAI 118
Query: 448 LISSGPKWRSHRKMIAPTF 504
++ +W+ R +++PTF
Sbjct: 119 SLAEDEEWKRIRSLLSPTF 137
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 37.1 bits (82), Expect = 0.036
Identities = 30/139 (21%), Positives = 61/139 (43%), Gaps = 2/139 (1%)
Frame = +1
Query: 94 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVN 273
N V + LL ++ + LY + + +L IPGP P+P+ GN L+ + L
Sbjct: 6 NLAVETWLLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVLSYRQ----GLWK 59
Query: 274 LALGYAQTFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGL 447
+ +G + + G ++ + D D I +L + T + P ++ +
Sbjct: 60 FDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECY-SVFTNRRSLGPVGFMKSAI 118
Query: 448 LISSGPKWRSHRKMIAPTF 504
++ +W+ R +++PTF
Sbjct: 119 SLAEDEEWKRIRSLLSPTF 137
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 37.1 bits (82), Expect = 0.036
Identities = 30/139 (21%), Positives = 61/139 (43%), Gaps = 2/139 (1%)
Frame = +1
Query: 94 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVN 273
N V + LL ++ + LY + + +L IPGP P+P+ GN L+ + L
Sbjct: 6 NLAVETWLLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVLSYRQ----GLWK 59
Query: 274 LALGYAQTFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGL 447
+ +G + + G ++ + D D I +L + T + P ++ +
Sbjct: 60 FDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECY-SVFTNRRSLGPVGFMKSAI 118
Query: 448 LISSGPKWRSHRKMIAPTF 504
++ +W+ R +++PTF
Sbjct: 119 SLAEDEEWKRIRSLLSPTF 137
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 36.7 bits (81), Expect = 0.048
Identities = 30/139 (21%), Positives = 61/139 (43%), Gaps = 2/139 (1%)
Frame = +1
Query: 94 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKDPHELVN 273
N V + LL ++ + LY + + +L IPGP P+P+ GN L+ + L
Sbjct: 6 NLAVETWLLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVLSYRQ----GLWK 59
Query: 274 LALGYAQTFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGL 447
+ +G + + G ++ + D D I +L + T + P ++ +
Sbjct: 60 FDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECY-SVFTNRRSLGPVGFMKSAI 118
Query: 448 LISSGPKWRSHRKMIAPTF 504
++ +W+ R +++PTF
Sbjct: 119 SLAEDEEWKRIRPLLSPTF 137
>AF280107-1|AAG32291.1| 106|Homo sapiens cytochrome P450
polypeptide 43 protein.
Length = 106
Score = 34.7 bits (76), Expect = 0.19
Identities = 24/86 (27%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSHMHKLAEL--IPGPAPIPIFGNALTLMRKDPHELVNLALGYAQTF 300
+ T++ +LY + +H HKL + IPGP P+P G L +R L N + +
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLR----GLWNFDRECNEKY 68
Query: 301 GNVVRVWLGSKLIVFLADADDIEIIL 378
G + ++ G + ++ + D D I+ +L
Sbjct: 69 GEMWGLYEGQQPMLVIMDPDMIKTVL 94
>BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 33.5 bits (73), Expect = 0.45
Identities = 29/107 (27%), Positives = 45/107 (42%), Gaps = 5/107 (4%)
Frame = +1
Query: 199 PGPAPIPIFGNALTLMRKD--PHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDIE- 369
PGP +P GN +L PH + +Q +G + + LG V L D ++
Sbjct: 41 PGPPGLPFIGNIYSLAASSELPHVYMR---KQSQVYGEIFSLDLGGISTVVLNGYDVVKE 97
Query: 370 -IILNSHVHIDKATEYKFFKPWLGEGLLISS-GPKWRSHRKMIAPTF 504
++ S + D+ F K GLL S G W HR++ +F
Sbjct: 98 CLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWVDHRRLAVNSF 144
>BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 33.5 bits (73), Expect = 0.45
Identities = 29/107 (27%), Positives = 45/107 (42%), Gaps = 5/107 (4%)
Frame = +1
Query: 199 PGPAPIPIFGNALTLMRKD--PHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDIE- 369
PGP +P GN +L PH + +Q +G + + LG V L D ++
Sbjct: 41 PGPPGLPFIGNIYSLAASSELPHVYMR---KQSQVYGEIFSLDLGGISTVVLNGYDVVKE 97
Query: 370 -IILNSHVHIDKATEYKFFKPWLGEGLLISS-GPKWRSHRKMIAPTF 504
++ S + D+ F K GLL S G W HR++ +F
Sbjct: 98 CLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWVDHRRLAVNSF 144
>AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1
protein.
Length = 501
Score = 33.5 bits (73), Expect = 0.45
Identities = 29/107 (27%), Positives = 45/107 (42%), Gaps = 5/107 (4%)
Frame = +1
Query: 199 PGPAPIPIFGNALTLMRKD--PHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDIE- 369
PGP +P GN +L PH + +Q +G + + LG V L D ++
Sbjct: 41 PGPPGLPFIGNIYSLAASSELPHVYMR---KQSQVYGEIFSLDLGGISTVVLNGYDVVKE 97
Query: 370 -IILNSHVHIDKATEYKFFKPWLGEGLLISS-GPKWRSHRKMIAPTF 504
++ S + D+ F K GLL S G W HR++ +F
Sbjct: 98 CLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWVDHRRLAVNSF 144
>X54807-1|CAA38578.1| 56|Homo sapiens unspecific monooxygenase
protein.
Length = 56
Score = 33.1 bits (72), Expect = 0.59
Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
Frame = +1
Query: 112 YPLLGLTTAIWILYR-WQQNSHMHKLAELIPGPAPIPIFGNALTLMRKD 255
+ +L L + +L+ W+Q+ KL PGP P+PI GN L + KD
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNMLQIDVKD 49
>U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450
monooxygenase CYP2J2 protein.
Length = 502
Score = 33.1 bits (72), Expect = 0.59
Identities = 25/101 (24%), Positives = 46/101 (45%), Gaps = 5/101 (4%)
Frame = +1
Query: 199 PGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDIEIIL 378
PGP +P GN + + H V L + + +GN+ + LG V + + +I
Sbjct: 45 PGPWRLPFLGNFFLVDFEQSHLEVQL---FVKKYGNLFSLELGDISAVLITG---LPLIK 98
Query: 379 NSHVHIDKATEYKFFKP-----WLGEGLLISSGPKWRSHRK 486
+ +H+D+ + P + GL++SSG W+ R+
Sbjct: 99 EALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRR 139
>BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 33.1 bits (72), Expect = 0.59
Identities = 25/101 (24%), Positives = 46/101 (45%), Gaps = 5/101 (4%)
Frame = +1
Query: 199 PGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDIEIIL 378
PGP +P GN + + H V L + + +GN+ + LG V + + +I
Sbjct: 45 PGPWRLPFLGNFFLVDFEQSHLEVQL---FVKKYGNLFSLELGDISAVLITG---LPLIK 98
Query: 379 NSHVHIDKATEYKFFKP-----WLGEGLLISSGPKWRSHRK 486
+ +H+D+ + P + GL++SSG W+ R+
Sbjct: 99 EALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRR 139
>AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 33.1 bits (72), Expect = 0.59
Identities = 25/101 (24%), Positives = 46/101 (45%), Gaps = 5/101 (4%)
Frame = +1
Query: 199 PGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDIEIIL 378
PGP +P GN + + H V L + + +GN+ + LG V + + +I
Sbjct: 45 PGPWRLPFLGNFFLVDFEQSHLEVQL---FVKKYGNLFSLELGDISAVLITG---LPLIK 98
Query: 379 NSHVHIDKATEYKFFKP-----WLGEGLLISSGPKWRSHRK 486
+ +H+D+ + P + GL++SSG W+ R+
Sbjct: 99 EALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRR 139
>AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein.
Length = 502
Score = 33.1 bits (72), Expect = 0.59
Identities = 25/101 (24%), Positives = 46/101 (45%), Gaps = 5/101 (4%)
Frame = +1
Query: 199 PGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDIEIIL 378
PGP +P GN + + H V L + + +GN+ + LG V + + +I
Sbjct: 45 PGPWRLPFLGNFFLVDFEQSHLEVQL---FVKKYGNLFSLELGDISAVLITG---LPLIK 98
Query: 379 NSHVHIDKATEYKFFKP-----WLGEGLLISSGPKWRSHRK 486
+ +H+D+ + P + GL++SSG W+ R+
Sbjct: 99 EALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRR 139
>AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450
epoxygenase protein.
Length = 339
Score = 33.1 bits (72), Expect = 0.59
Identities = 25/101 (24%), Positives = 46/101 (45%), Gaps = 5/101 (4%)
Frame = +1
Query: 199 PGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDIEIIL 378
PGP +P GN + + H V L + + +GN+ + LG V + + +I
Sbjct: 14 PGPWRLPFLGNFFLVDFEQSHLEVQL---FVKKYGNLFSLELGDISAVLITG---LPLIK 67
Query: 379 NSHVHIDKATEYKFFKP-----WLGEGLLISSGPKWRSHRK 486
+ +H+D+ + P + GL++SSG W+ R+
Sbjct: 68 EALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRR 108
>AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2
protein.
Length = 502
Score = 33.1 bits (72), Expect = 0.59
Identities = 25/101 (24%), Positives = 46/101 (45%), Gaps = 5/101 (4%)
Frame = +1
Query: 199 PGPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDIEIIL 378
PGP +P GN + + H V L + + +GN+ + LG V + + +I
Sbjct: 45 PGPWRLPFLGNFFLVDFEQSHLEVQL---FVKKYGNLFSLELGDISAVLITG---LPLIK 98
Query: 379 NSHVHIDKATEYKFFKP-----WLGEGLLISSGPKWRSHRK 486
+ +H+D+ + P + GL++SSG W+ R+
Sbjct: 99 EALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRR 139
>BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein.
Length = 393
Score = 32.7 bits (71), Expect = 0.78
Identities = 17/53 (32%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSHMHKLAEL--IPGPAPIPIFGNALTLMRKDPHELVNLA 279
+ T++ +LY + +H HKL + IPGP P+P G L +R+ +++ + A
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLRRSLNKIPSWA 65
>AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein.
Length = 516
Score = 32.7 bits (71), Expect = 0.78
Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 6/133 (4%)
Frame = +1
Query: 121 LGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTL-MRKDPHELVNLALGYAQT 297
L + AI++L + H A PGP P+P GN L + + P+ L +
Sbjct: 9 LAMIVAIFLLLVDLMHRHQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDV 68
Query: 298 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDK--ATEYKF--FKPWLGEGLLISS-G 462
F N+ W ++ LA + ++ D+ A Y+ F P +G+++S G
Sbjct: 69 F-NLQLAWTPVVVLNGLAAVRE-AMVTRGEDTADRPPAPIYQVLGFGP-RSQGVILSRYG 125
Query: 463 PKWRSHRKMIAPT 501
P WR R+ T
Sbjct: 126 PAWREQRRFSVST 138
>X56452-1|CAA39833.1| 56|Homo sapiens unspecific monooxygenase
protein.
Length = 56
Score = 31.9 bits (69), Expect = 1.4
Identities = 16/41 (39%), Positives = 24/41 (58%)
Frame = +1
Query: 133 TAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRKD 255
+ +++L W+Q+S +L GP P+PI GN L L KD
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVKD 49
>BC004367-1|AAH04367.1| 313|Homo sapiens potassium channel,
subfamily K, member 6 protein.
Length = 313
Score = 31.5 bits (68), Expect = 1.8
Identities = 17/44 (38%), Positives = 22/44 (50%)
Frame = +1
Query: 103 VIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNA 234
V Y LGL + +L ++ S +H L ELI P P P NA
Sbjct: 238 VTVYLFLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNA 281
>AK222545-1|BAD96265.1| 313|Homo sapiens potassium channel,
subfamily K, member 6 variant protein.
Length = 313
Score = 31.5 bits (68), Expect = 1.8
Identities = 17/44 (38%), Positives = 22/44 (50%)
Frame = +1
Query: 103 VIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNA 234
V Y LGL + +L ++ S +H L ELI P P P NA
Sbjct: 238 VTVYLFLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNA 281
>AJ297404-1|CAC15489.1| 313|Homo sapiens potassium channel,
subfamily K, member 6 (TWIK-2) protein.
Length = 313
Score = 31.5 bits (68), Expect = 1.8
Identities = 17/44 (38%), Positives = 22/44 (50%)
Frame = +1
Query: 103 VIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNA 234
V Y LGL + +L ++ S +H L ELI P P P NA
Sbjct: 238 VTVYLFLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNA 281
>AF281303-1|AAG10507.1| 179|Homo sapiens 2P domain K+ channel
TWIK-2 protein.
Length = 179
Score = 31.5 bits (68), Expect = 1.8
Identities = 17/44 (38%), Positives = 22/44 (50%)
Frame = +1
Query: 103 VIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNA 234
V Y LGL + +L ++ S +H L ELI P P P NA
Sbjct: 104 VTVYLFLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNA 147
>AF281302-1|AAG10506.1| 313|Homo sapiens 2P domain K+ channel
TWIK-2 protein.
Length = 313
Score = 31.5 bits (68), Expect = 1.8
Identities = 17/44 (38%), Positives = 22/44 (50%)
Frame = +1
Query: 103 VIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNA 234
V Y LGL + +L ++ S +H L ELI P P P NA
Sbjct: 238 VTVYLFLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNA 281
>AF134149-1|AAD22980.1| 313|Homo sapiens 2-pore K+ channel subunit
TOSS protein.
Length = 313
Score = 31.5 bits (68), Expect = 1.8
Identities = 17/44 (38%), Positives = 22/44 (50%)
Frame = +1
Query: 103 VIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNA 234
V Y LGL + +L ++ S +H L ELI P P P NA
Sbjct: 238 VTVYLFLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNA 281
>AF117708-1|AAD24000.1| 313|Homo sapiens tandem pore domain
potassium channel TWIK-2 protein.
Length = 313
Score = 31.5 bits (68), Expect = 1.8
Identities = 17/44 (38%), Positives = 22/44 (50%)
Frame = +1
Query: 103 VIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNA 234
V Y LGL + +L ++ S +H L ELI P P P NA
Sbjct: 238 VTVYLFLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNA 281
>DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 31.1 bits (67), Expect = 2.4
Identities = 35/134 (26%), Positives = 52/134 (38%), Gaps = 7/134 (5%)
Frame = +1
Query: 121 LGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTL-MRKDPHELVNLALGYAQT 297
L + AI++L + H A PGP P+P GN L + + P+ L +
Sbjct: 9 LAVIVAIFLLLVDLMHRHQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQL----RRR 64
Query: 298 FGNVVRVWLGSKLIVFLADADDIEIILNSHVH--IDK----ATEYKFFKPWLGEGLLISS 459
FG+V + L +V L + L +H D+ T+ F P L
Sbjct: 65 FGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARY 124
Query: 460 GPKWRSHRKMIAPT 501
GP WR R+ T
Sbjct: 125 GPAWREQRRFSVST 138
>AF280113-1|AAG33014.1| 74|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 74
Score = 31.1 bits (67), Expect = 2.4
Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSHMHKLAEL--IPGPAPIPIFGNALTLMR 249
+ T++ +LY + +H HKL + IPGP P+P G L +R
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLR 55
>AF280112-1|AAG33013.1| 126|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 126
Score = 31.1 bits (67), Expect = 2.4
Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSHMHKLAEL--IPGPAPIPIFGNALTLMR 249
+ T++ +LY + +H HKL + IPGP P+P G L +R
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLR 55
>AF183185-1|AAG12991.1| 1997|Homo sapiens brain otoferlin long
isoform protein.
Length = 1997
Score = 30.7 bits (66), Expect = 3.2
Identities = 20/69 (28%), Positives = 36/69 (52%)
Frame = +1
Query: 202 GPAPIPIFGNALTLMRKDPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDIEIILN 381
GPA + ++G+ D H+ +N LG +F R+ LG L V + D + E+ +
Sbjct: 533 GPAWVNMYGSTRNYTLLDEHQDLNEGLGEGVSFR--ARLLLG--LAVEIVDTSNPELTSS 588
Query: 382 SHVHIDKAT 408
+ V +++AT
Sbjct: 589 TEVQVEQAT 597
>AK024290-1|BAB14875.1| 590|Homo sapiens protein ( Homo sapiens
cDNA FLJ14228 fis, clone NT2RP3004148. ).
Length = 590
Score = 30.3 bits (65), Expect = 4.2
Identities = 13/28 (46%), Positives = 18/28 (64%)
Frame = +1
Query: 73 ETEGYHVNSRVIFYPLLGLTTAIWILYR 156
E + V +R +FYPLLGL A+ + YR
Sbjct: 372 EVQRKEVQARAVFYPLLGLGGAVNMCYR 399
>AF280107-4|AAG32288.1| 106|Homo sapiens cytochrome P450
polypeptide 5 protein.
Length = 106
Score = 30.3 bits (65), Expect = 4.2
Identities = 16/49 (32%), Positives = 26/49 (53%)
Frame = +1
Query: 94 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALT 240
N V + LL ++ + LY + + +L IPGP P+P+ GN L+
Sbjct: 6 NLAVETWLLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVLS 52
>AB040956-1|BAA96047.1| 687|Homo sapiens KIAA1523 protein protein.
Length = 687
Score = 30.3 bits (65), Expect = 4.2
Identities = 13/28 (46%), Positives = 18/28 (64%)
Frame = +1
Query: 73 ETEGYHVNSRVIFYPLLGLTTAIWILYR 156
E + V +R +FYPLLGL A+ + YR
Sbjct: 469 EVQRKEVQARAVFYPLLGLGGAVNMCYR 496
>AF081569-1|AAD25924.1| 52|Homo sapiens cytochrome P450 protein.
Length = 52
Score = 29.1 bits (62), Expect = 9.7
Identities = 15/42 (35%), Positives = 23/42 (54%)
Frame = +1
Query: 127 LTTAIWILYRWQQNSHMHKLAELIPGPAPIPIFGNALTLMRK 252
LT + +L + N+H L PGP P+P+ GN L + R+
Sbjct: 12 LTGLLLLLVQRHPNTH----DRLPPGPRPLPLLGNLLQMDRR 49
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 81,898,913
Number of Sequences: 237096
Number of extensions: 1801582
Number of successful extensions: 3643
Number of sequences better than 10.0: 225
Number of HSP's better than 10.0 without gapping: 3458
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3595
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4876707572
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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