BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= epV30528 (508 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q7PPI8 Cluster: ENSANGP00000022232; n=3; Endopterygota|... 203 2e-51 UniRef50_P81900 Cluster: cAMP-dependent protein kinase type II r... 196 2e-49 UniRef50_Q5DI18 Cluster: SJCHGC02266 protein; n=1; Schistosoma j... 167 1e-40 UniRef50_P31323 Cluster: cAMP-dependent protein kinase type II-b... 167 1e-40 UniRef50_Q4RSC3 Cluster: Chromosome 13 SCAF15000, whole genome s... 162 5e-39 UniRef50_P31320 Cluster: cAMP-dependent protein kinase regulator... 126 3e-28 UniRef50_Q4TGP1 Cluster: Chromosome undetermined SCAF3574, whole... 124 1e-27 UniRef50_A7RGJ3 Cluster: Predicted protein; n=1; Nematostella ve... 119 3e-26 UniRef50_A7S513 Cluster: Predicted protein; n=1; Nematostella ve... 116 2e-25 UniRef50_Q5DAR5 Cluster: SJCHGC05163 protein; n=1; Schistosoma j... 113 2e-24 UniRef50_P10644 Cluster: cAMP-dependent protein kinase type I-al... 107 1e-22 UniRef50_A6SCU8 Cluster: Putative uncharacterized protein; n=2; ... 106 3e-22 UniRef50_Q86ZN7 Cluster: cAMP-dependent protein kinase regulator... 104 1e-21 UniRef50_Q5H7P2 Cluster: CAMP-dependent protein kinase regulator... 104 1e-21 UniRef50_Q9HFV9 Cluster: CAMP dependent protein kinase regulator... 101 9e-21 UniRef50_Q240X5 Cluster: Cyclic nucleotide-binding domain contai... 97 3e-19 UniRef50_Q9HEW1 Cluster: cAMP-dependent protein kinase regulator... 96 5e-19 UniRef50_Q9BMY7 Cluster: CAMP-dependent protein kinase regulator... 95 1e-18 UniRef50_Q22NC5 Cluster: Cyclic nucleotide-binding domain contai... 95 1e-18 UniRef50_P07278 Cluster: cAMP-dependent protein kinase regulator... 94 1e-18 UniRef50_Q7KQK0 Cluster: CAMP-dependent protein kinase regulator... 93 2e-18 UniRef50_A0DZ01 Cluster: Chromosome undetermined scaffold_7, who... 92 6e-18 UniRef50_Q3SED2 Cluster: CAMP-dependent protein kinase, regulato... 92 8e-18 UniRef50_A0CJF2 Cluster: Chromosome undetermined scaffold_2, who... 91 1e-17 UniRef50_P49605 Cluster: cAMP-dependent protein kinase regulator... 90 3e-17 UniRef50_Q8TF77 Cluster: cAMP-dependent protein kinase regulator... 90 3e-17 UniRef50_UPI0001509E09 Cluster: cyclic nucleotide-binding domain... 88 1e-16 UniRef50_P05987 Cluster: cAMP-dependent protein kinase regulator... 87 2e-16 UniRef50_A0BNE3 Cluster: Chromosome undetermined scaffold_118, w... 87 3e-16 UniRef50_Q6C2X0 Cluster: cAMP-dependent protein kinase regulator... 87 3e-16 UniRef50_Q9XTM6 Cluster: CAMP-dependent protein kinase regulator... 86 4e-16 UniRef50_A0BRC9 Cluster: Chromosome undetermined scaffold_122, w... 86 4e-16 UniRef50_Q4UEK0 Cluster: CAMP-dependent protein kinase regulator... 86 5e-16 UniRef50_Q33DX2 Cluster: Putative cyclic AMP-dependent protein k... 69 1e-15 UniRef50_A2R984 Cluster: Catalytic activity: ATP + a protein <=>... 84 2e-15 UniRef50_A3FPL6 Cluster: CAMP-dependent protein kinase regulator... 83 3e-15 UniRef50_A7AU83 Cluster: cAMP-dependent protein kinase regulator... 81 1e-14 UniRef50_P36600 Cluster: cAMP-dependent protein kinase regulator... 81 2e-14 UniRef50_A0CMC2 Cluster: Chromosome undetermined scaffold_21, wh... 78 1e-13 UniRef50_UPI0000D562F1 Cluster: PREDICTED: similar to CG3324-PA;... 74 2e-12 UniRef50_Q3SEP0 Cluster: CGMP-dependent protein kinase 8-2; n=8;... 71 2e-11 UniRef50_Q8MQE4 Cluster: Putative uncharacterized protein; n=5; ... 69 5e-11 UniRef50_UPI000065ED67 Cluster: cAMP-dependent protein kinase ty... 69 6e-11 UniRef50_Q03042 Cluster: cGMP-dependent protein kinase, isozyme ... 69 8e-11 UniRef50_Q13237 Cluster: cGMP-dependent protein kinase 2; n=23; ... 67 2e-10 UniRef50_A7C1J1 Cluster: Protein kinase, cGMP-dependent, type I;... 66 3e-10 UniRef50_Q5CWD4 Cluster: Cyclic nucleotide (CGMP)-dependent prot... 66 3e-10 UniRef50_A0E3G7 Cluster: Chromosome undetermined scaffold_76, wh... 66 6e-10 UniRef50_A2EKL9 Cluster: Cyclic nucleotide-binding domain contai... 65 8e-10 UniRef50_Q8MMZ4 Cluster: CGMP-dependent protein kinase; n=14; Ap... 65 1e-09 UniRef50_Q22RR1 Cluster: Protein kinase domain containing protei... 65 1e-09 UniRef50_Q9FXQ0 Cluster: Cyclic nucreotide dependent protein kin... 64 2e-09 UniRef50_Q234E6 Cluster: Protein kinase domain containing protei... 64 2e-09 UniRef50_UPI0000DB6E55 Cluster: PREDICTED: similar to cGMP-depen... 63 3e-09 UniRef50_Q31QH3 Cluster: Cyclic nucleotide-binding; n=2; Synecho... 63 3e-09 UniRef50_Q22SE3 Cluster: Cyclic nucleotide-binding domain contai... 63 3e-09 UniRef50_A0D9C4 Cluster: Chromosome undetermined scaffold_42, wh... 62 5e-09 UniRef50_Q0LLK2 Cluster: Stage II sporulation E; n=1; Herpetosip... 62 7e-09 UniRef50_A0DCJ0 Cluster: Chromosome undetermined scaffold_45, wh... 62 7e-09 UniRef50_UPI0000660D74 Cluster: Homolog of Homo sapiens "cGMP-de... 62 9e-09 UniRef50_Q01E02 Cluster: CGMP-dependent protein kinase, putative... 56 1e-08 UniRef50_A4S6U9 Cluster: Predicted protein; n=2; Ostreococcus|Re... 61 1e-08 UniRef50_Q16JU3 Cluster: Cgmp-dependent protein kinase; n=2; End... 61 2e-08 UniRef50_Q8MMZ5 Cluster: CGMP-dependent protein kinase; n=2; Eim... 60 3e-08 UniRef50_O76360 Cluster: Egg laying defective protein 4, isoform... 60 3e-08 UniRef50_UPI0000519F68 Cluster: PREDICTED: similar to cGMP-depen... 60 4e-08 UniRef50_Q6P5T7 Cluster: PRKG1 protein; n=14; Euteleostomi|Rep: ... 60 4e-08 UniRef50_P14619 Cluster: cGMP-dependent protein kinase 1, beta i... 60 4e-08 UniRef50_Q5RGL5 Cluster: Novel protein similar to vertebrate pro... 59 5e-08 UniRef50_A7PEK0 Cluster: Chromosome chr11 scaffold_13, whole gen... 59 5e-08 UniRef50_O17474 Cluster: Cyclic GMP-dependent protein kinase; n=... 59 7e-08 UniRef50_Q2HGG6 Cluster: Putative uncharacterized protein; n=1; ... 59 7e-08 UniRef50_A4TWF8 Cluster: Na+/H+ Antiporter; n=1; Magnetospirillu... 58 1e-07 UniRef50_Q9VL34 Cluster: CG4839-PA, isoform A; n=2; Sophophora|R... 57 2e-07 UniRef50_A0YP22 Cluster: Putative uncharacterized protein; n=1; ... 57 3e-07 UniRef50_Q23DN8 Cluster: Cyclic nucleotide-binding domain contai... 57 3e-07 UniRef50_Q8DKN0 Cluster: Tlr0829 protein; n=1; Synechococcus elo... 56 3e-07 UniRef50_Q4Q2R2 Cluster: Regulatory subunit of protein kinase a-... 56 3e-07 UniRef50_A0BE58 Cluster: Chromosome undetermined scaffold_101, w... 56 3e-07 UniRef50_Q8SRB5 Cluster: CAMP-DEPENDENT PROTEIN KINASE TYPE 1 RE... 56 3e-07 UniRef50_Q4SL71 Cluster: Chromosome 17 SCAF14563, whole genome s... 56 5e-07 UniRef50_Q8CXT1 Cluster: CAMP-dependent protein kinase regulator... 56 6e-07 UniRef50_A5GVU5 Cluster: ABC-type multidrug transport system, AT... 55 8e-07 UniRef50_Q4RR21 Cluster: Chromosome 14 SCAF15003, whole genome s... 55 1e-06 UniRef50_A3IKE0 Cluster: Putative uncharacterized protein; n=1; ... 55 1e-06 UniRef50_A0E0G1 Cluster: Chromosome undetermined scaffold_71, wh... 55 1e-06 UniRef50_Q08V69 Cluster: PKA regulatory subunit-like protein; n=... 54 1e-06 UniRef50_A7BXC8 Cluster: MscS Mechanosensitive ion channel; n=1;... 54 1e-06 UniRef50_Q3MD80 Cluster: Cyclic nucleotide-binding domain (CNMP-... 54 2e-06 UniRef50_A7C147 Cluster: cGMP-dependent protein kinase type I; n... 54 2e-06 UniRef50_Q6WL05 Cluster: Hyperpolarization-activated ion channel... 53 3e-06 UniRef50_Q5QFC4 Cluster: EnvDll2-01; n=1; Oikopleura dioica|Rep:... 53 3e-06 UniRef50_Q4QGD8 Cluster: Protein kinase A regulatory subunit, pu... 53 4e-06 UniRef50_Q4QF64 Cluster: Protein kinase, putative; n=2; Leishman... 53 4e-06 UniRef50_Q9M8S6 Cluster: Potassium channel SKOR (Stelar K(+) out... 53 4e-06 UniRef50_UPI0000383B9A Cluster: COG0642: Signal transduction his... 52 7e-06 UniRef50_Q5WUW4 Cluster: Putative uncharacterized protein; n=4; ... 52 7e-06 UniRef50_Q1D8K7 Cluster: Mechanosensitive ion channel/cyclic nuc... 52 7e-06 UniRef50_Q9Y3Q4 Cluster: Potassium/sodium hyperpolarization-acti... 52 7e-06 UniRef50_Q4S874 Cluster: Chromosome 5 SCAF14709, whole genome sh... 52 1e-05 UniRef50_A5G0B9 Cluster: Putative transcriptional regulator, Crp... 52 1e-05 UniRef50_UPI0000EC9F34 Cluster: UPI0000EC9F34 related cluster; n... 51 1e-05 UniRef50_A1Z9N7 Cluster: CG8585-PE, isoform E; n=18; Pancrustace... 51 1e-05 UniRef50_UPI000038CAE7 Cluster: COG1012: NAD-dependent aldehyde ... 51 2e-05 UniRef50_Q2RX44 Cluster: Cyclic nucleotide-binding domain (CNMP-... 51 2e-05 UniRef50_Q10V66 Cluster: Cyclic nucleotide-binding protein; n=2;... 51 2e-05 UniRef50_A5UY70 Cluster: Cyclic nucleotide-binding protein; n=3;... 51 2e-05 UniRef50_Q125U4 Cluster: Transcriptional regulator, Crp/Fnr fami... 50 2e-05 UniRef50_A0GWU5 Cluster: Stage II sporulation E; n=2; Chloroflex... 50 2e-05 UniRef50_A0DBC7 Cluster: Chromosome undetermined scaffold_44, wh... 50 2e-05 UniRef50_Q2ADG0 Cluster: Cyclic nucleotide-binding:Bacterial reg... 50 3e-05 UniRef50_Q1D5Q4 Cluster: Cyclic nucleotide-binding domain protei... 50 3e-05 UniRef50_Q2LPZ1 Cluster: Cyclic nucleotide-binding domain protei... 50 4e-05 UniRef50_P74608 Cluster: Slr1575 protein; n=1; Synechocystis sp.... 50 4e-05 UniRef50_Q08NQ8 Cluster: Protein phosphatase 1; n=2; Cystobacter... 50 4e-05 UniRef50_Q2VWB6 Cluster: CAMP-dependent protein kinase A regulat... 50 4e-05 UniRef50_Q23WN2 Cluster: Cyclic nucleotide-binding domain contai... 50 4e-05 UniRef50_O76977 Cluster: Hyperpolarization-activated (Ih) channe... 50 4e-05 UniRef50_UPI000038CAE8 Cluster: COG1252: NADH dehydrogenase, FAD... 49 5e-05 UniRef50_Q98GM7 Cluster: Mlr3256 protein; n=2; Alphaproteobacter... 49 5e-05 UniRef50_Q8XR93 Cluster: Probable transcription regulator protei... 49 5e-05 UniRef50_Q23EB7 Cluster: Cyclic nucleotide-binding domain contai... 49 5e-05 UniRef50_P63401 Cluster: Uncharacterized ABC transporter ATP-bin... 49 5e-05 UniRef50_Q46TY3 Cluster: Cyclic nucleotide-binding; n=2; Cupriav... 49 7e-05 UniRef50_A3YU60 Cluster: Putative glutaminase; n=1; Synechococcu... 49 7e-05 UniRef50_A0YHV0 Cluster: Putative uncharacterized protein; n=1; ... 49 7e-05 UniRef50_A0DG99 Cluster: Chromosome undetermined scaffold_5, who... 49 7e-05 UniRef50_Q3AAI0 Cluster: CBS/cyclic nucleotide-binding domain pr... 48 9e-05 UniRef50_Q0VQV6 Cluster: Cyclic nucleotide-binding domain protei... 48 9e-05 UniRef50_A3YU63 Cluster: Possible mechanosensitive ion channel; ... 48 9e-05 UniRef50_Q2SDD5 Cluster: CAMP-binding protein-catabolite gene ac... 48 1e-04 UniRef50_Q3W7N0 Cluster: Cyclic nucleotide-binding domain:Peptid... 48 1e-04 UniRef50_A6G0I3 Cluster: Putative uncharacterized protein; n=1; ... 48 1e-04 UniRef50_Q22R60 Cluster: Cyclic nucleotide-binding domain contai... 48 1e-04 UniRef50_A7SFW1 Cluster: Predicted protein; n=1; Nematostella ve... 48 1e-04 UniRef50_A3EYY6 Cluster: Tetrameric potassium-selective cyclic n... 48 1e-04 UniRef50_UPI00006CA698 Cluster: cation channel family protein; n... 48 2e-04 UniRef50_Q6MJQ6 Cluster: Hyperpolarization-activated, cyclic nuc... 48 2e-04 UniRef50_Q2S6T5 Cluster: CAMP-binding protein-catabolite gene ac... 48 2e-04 UniRef50_Q2RK98 Cluster: Transcriptional regulator, Crp/Fnr fami... 48 2e-04 UniRef50_Q2LV90 Cluster: CAMP-dependent transcriptional regulato... 48 2e-04 UniRef50_A0LIE9 Cluster: Cyclic nucleotide-binding protein; n=1;... 48 2e-04 UniRef50_Q1NMR4 Cluster: Cyclic nucleotide-binding; n=2; delta p... 47 2e-04 UniRef50_Q1D9I5 Cluster: PBS lyase HEAT-like repeat/cyclic nucle... 47 2e-04 UniRef50_Q0LJ13 Cluster: Cyclic nucleotide-binding; n=2; Chlorof... 47 2e-04 UniRef50_Q0F2T2 Cluster: Glucose-6-phosphate 1-dehydrogenase; n=... 47 2e-04 UniRef50_Q09BB2 Cluster: Cyclic nucleotide-binding:Bacterial reg... 47 2e-04 UniRef50_Q05VE2 Cluster: Possible mechanosensitive ion channel; ... 47 2e-04 UniRef50_Q7K3Z6 Cluster: GH01501p; n=4; Diptera|Rep: GH01501p - ... 47 2e-04 UniRef50_Q131K0 Cluster: Cyclic nucleotide-binding precursor; n=... 47 3e-04 UniRef50_Q5CD46 Cluster: PKA regulatory subunit homologous prote... 47 3e-04 UniRef50_A0YM45 Cluster: Sulfate transporter family protein; n=1... 47 3e-04 UniRef50_Q4D6P2 Cluster: Regulatory subunit of protein kinase a-... 47 3e-04 UniRef50_Q10898 Cluster: Uncharacterized protein Rv0104/MT0113; ... 47 3e-04 UniRef50_UPI00006CA699 Cluster: cyclic nucleotide-binding domain... 46 4e-04 UniRef50_UPI00006A1C4D Cluster: Uncharacterized protein C20orf15... 46 4e-04 UniRef50_Q30Y06 Cluster: Transcriptional regulator, Crp/Fnr fami... 46 4e-04 UniRef50_Q7CWQ8 Cluster: AGR_C_4670p; n=6; Rhizobiaceae|Rep: AGR... 46 4e-04 UniRef50_A6G5Y4 Cluster: Protein phosphatase/cyclic nucleotide-b... 46 4e-04 UniRef50_Q695H0 Cluster: CGMP-dependent protein kinase; n=1; Chl... 46 4e-04 UniRef50_A5PH37 Cluster: AKT2 inward rectifier channel; n=6; Emb... 46 4e-04 UniRef50_Q4CSS9 Cluster: Protein kinase, putative; n=2; Trypanos... 46 4e-04 UniRef50_Q23EB4 Cluster: ABC transporter family protein; n=3; Te... 46 4e-04 UniRef50_A0CY63 Cluster: Chromosome undetermined scaffold_301, w... 46 4e-04 UniRef50_Q8WZA2 Cluster: Rap guanine nucleotide exchange factor ... 46 4e-04 UniRef50_Q2K3Q8 Cluster: Probable cation transporter protein; n=... 46 5e-04 UniRef50_Q7RDH4 Cluster: Reticulocyte-binding protein 2 homolog ... 46 5e-04 UniRef50_A0DKC6 Cluster: Chromosome undetermined scaffold_54, wh... 46 5e-04 UniRef50_Q9P1Z3 Cluster: Potassium/sodium hyperpolarization-acti... 46 5e-04 UniRef50_UPI0000EC9E1A Cluster: Rap guanine nucleotide exchange ... 46 7e-04 UniRef50_Q2WA28 Cluster: CheY-like receiver; n=3; Magnetospirill... 46 7e-04 UniRef50_Q1YDI6 Cluster: Possible cAMP-dependent regulatory prot... 46 7e-04 UniRef50_Q09BB3 Cluster: PKA regulatory subunit-like protein; n=... 46 7e-04 UniRef50_A7BRS9 Cluster: Transcriptional Regulator, Crp/Fnr fami... 46 7e-04 UniRef50_A6G7H5 Cluster: Serine/threonine-protein kinase; n=2; P... 46 7e-04 UniRef50_A5UZM8 Cluster: Cyclic nucleotide-binding protein; n=3;... 46 7e-04 UniRef50_A0YLS1 Cluster: Putative uncharacterized protein; n=1; ... 46 7e-04 UniRef50_A0YAY7 Cluster: CAMP-binding protein-catabolite gene ac... 46 7e-04 UniRef50_Q554K9 Cluster: CGMP-stimulated cGMP phosphodiesterase;... 46 7e-04 UniRef50_A7SKJ5 Cluster: Predicted protein; n=2; Nematostella ve... 46 7e-04 UniRef50_Q7UTR3 Cluster: ATP-binding subunit of ABC transporter;... 45 9e-04 UniRef50_Q5P0W6 Cluster: Transcriptional regulator, Dnr/Nnr type... 45 9e-04 UniRef50_Q1PUQ2 Cluster: Similar to transcriptional regulator of... 45 9e-04 UniRef50_Q8ILS1 Cluster: Putative uncharacterized protein; n=1; ... 45 9e-04 UniRef50_Q23DN4 Cluster: Cyclic nucleotide-binding domain contai... 45 9e-04 UniRef50_A0DVS8 Cluster: Chromosome undetermined scaffold_66, wh... 45 9e-04 UniRef50_O95398 Cluster: Rap guanine nucleotide exchange factor ... 45 9e-04 UniRef50_UPI000065E24B Cluster: Rap guanine nucleotide exchange ... 45 0.001 UniRef50_UPI000065D7C1 Cluster: Homolog of Oncorhynchus mykiss "... 45 0.001 UniRef50_Q92SD2 Cluster: PUTATIVE TRANSCRIPTION REGULATOR PROTEI... 45 0.001 UniRef50_Q6ANR0 Cluster: Related to nitrogen assimilation regula... 45 0.001 UniRef50_Q935V9 Cluster: Transcriptional regulator with cyclic n... 45 0.001 UniRef50_Q1DAY2 Cluster: Cyclic nucleotide-binding domain protei... 45 0.001 UniRef50_A4M043 Cluster: Transcriptional regulator, Crp/Fnr fami... 45 0.001 UniRef50_A4RUE3 Cluster: Predicted protein; n=1; Ostreococcus lu... 45 0.001 UniRef50_UPI00006CFEF7 Cluster: cation channel family protein; n... 44 0.002 UniRef50_Q7D4Z5 Cluster: Drug transporter; n=19; Mycobacterium|R... 44 0.002 UniRef50_Q2YZI3 Cluster: Putative uncharacterized protein; n=1; ... 44 0.002 UniRef50_A7BVI5 Cluster: Reductase; n=1; Beggiatoa sp. PS|Rep: R... 44 0.002 UniRef50_A1IBE9 Cluster: Putative transcriptional regulator, Crp... 44 0.002 UniRef50_A0NZP6 Cluster: CAAX amino terminal protease family pro... 44 0.002 UniRef50_Q00X68 Cluster: Cyclic nucleotide dependent protein kin... 44 0.002 UniRef50_A7SE96 Cluster: Predicted protein; n=1; Nematostella ve... 44 0.002 UniRef50_Q7V424 Cluster: Possible mechanosensitive ion channel; ... 44 0.002 UniRef50_Q6MLN6 Cluster: Putative uncharacterized protein; n=1; ... 44 0.002 UniRef50_Q3JAP3 Cluster: Cyclic nucleotide-binding protein; n=1;... 44 0.002 UniRef50_Q1GWA6 Cluster: Cyclic nucleotide-binding protein precu... 44 0.002 UniRef50_Q0VS63 Cluster: Cyclic nucleotide-binding protein; n=1;... 44 0.002 UniRef50_Q59V20 Cluster: Putative uncharacterized protein; n=1; ... 44 0.002 UniRef50_Q4WI41 Cluster: Cyclic nucleotide-binding domain protei... 44 0.002 UniRef50_A1CZ15 Cluster: Cyclic nucleotide-binding domain protei... 44 0.002 UniRef50_UPI00006CC0E9 Cluster: cation channel family protein; n... 44 0.003 UniRef50_Q2S8X4 Cluster: CAMP-binding protein-catabolite gene ac... 44 0.003 UniRef50_P74736 Cluster: CAMP protein kinase regulatory chain; n... 44 0.003 UniRef50_Q9X7J4 Cluster: DnrD protein; n=9; Pseudomonas|Rep: Dnr... 44 0.003 UniRef50_Q7D903 Cluster: Cyclic nucleotide-binding protein; n=19... 44 0.003 UniRef50_Q13J41 Cluster: Transcriptional regulator, Crp/Fnr fami... 44 0.003 UniRef50_A0YCM5 Cluster: CAMP-binding protein-catabolite gene ac... 44 0.003 UniRef50_A0LNC0 Cluster: Cyclic nucleotide-binding protein; n=1;... 44 0.003 UniRef50_A0L6N5 Cluster: Cyclic nucleotide-binding; n=1; Magneto... 44 0.003 UniRef50_Q24DS4 Cluster: Cation channel family protein; n=1; Tet... 44 0.003 UniRef50_Q23EB1 Cluster: Cation channel family protein; n=2; Tet... 44 0.003 UniRef50_A0BGA2 Cluster: Chromosome undetermined scaffold_105, w... 44 0.003 UniRef50_Q6C384 Cluster: Similar to DEHA0B08261g Debaryomyces ha... 44 0.003 UniRef50_A3LZH5 Cluster: Leucine rich repeat protein, contains F... 44 0.003 UniRef50_UPI0000F1F638 Cluster: PREDICTED: similar to putative c... 43 0.003 UniRef50_UPI00006D001F Cluster: cyclic nucleotide-binding domain... 43 0.003 UniRef50_Q97TL8 Cluster: CRP (Cyclic AMP receptor protein) regul... 43 0.003 UniRef50_Q746U7 Cluster: Transcriptional regulator, Crp/Fnr fami... 43 0.003 UniRef50_Q31NU6 Cluster: Cyclic nucleotide-binding domain (CNMP-... 43 0.003 UniRef50_A0XC88 Cluster: Cyclic nucleotide-binding; n=1; Dinoros... 43 0.003 UniRef50_Q236Y9 Cluster: Cyclic nucleotide-binding domain contai... 43 0.003 UniRef50_A0DXZ3 Cluster: Chromosome undetermined scaffold_69, wh... 43 0.003 UniRef50_Q1D9D3 Cluster: Cyclic nucleotide-binding domain protei... 43 0.005 UniRef50_A7BRE2 Cluster: Protein kinase, cGMP-dependent, type I;... 43 0.005 UniRef50_A5GPF7 Cluster: Conserved hyppthetical protein; n=1; Sy... 43 0.005 UniRef50_A1ZG79 Cluster: Transporter, small conductance mechanos... 43 0.005 UniRef50_A7RK87 Cluster: Predicted protein; n=1; Nematostella ve... 43 0.005 UniRef50_Q03611 Cluster: Cyclic nucleotide-gated cation channel;... 43 0.005 UniRef50_Q9NQW8 Cluster: Cyclic nucleotide-gated cation channel ... 43 0.005 UniRef50_UPI000155D050 Cluster: PREDICTED: similar to Cyclic nuc... 42 0.006 UniRef50_Q5NXU3 Cluster: Catabolite gene activator; n=3; Rhodocy... 42 0.006 UniRef50_Q55427 Cluster: Slr0842 protein; n=1; Synechocystis sp.... 42 0.006 UniRef50_Q1GTY7 Cluster: Transcriptional regulator, Crp/Fnr fami... 42 0.006 UniRef50_A4TW60 Cluster: cAMP-binding protein-catabolite gene ac... 42 0.006 UniRef50_Q23EB3 Cluster: Cyclic nucleotide-binding domain contai... 42 0.006 UniRef50_Q23AA4 Cluster: Cation channel family protein; n=1; Tet... 42 0.006 UniRef50_A7SKJ9 Cluster: Predicted protein; n=1; Nematostella ve... 42 0.006 UniRef50_A0E9X9 Cluster: Chromosome undetermined scaffold_85, wh... 42 0.006 UniRef50_A0E001 Cluster: Chromosome undetermined scaffold_70, wh... 42 0.006 UniRef50_P0A642 Cluster: Uncharacterized NTE family protein Rv25... 42 0.006 UniRef50_Q8CXU7 Cluster: CAMP-dependent protein kinase regulator... 42 0.008 UniRef50_Q7MBF0 Cluster: Probable transcriptional regulator, Crp... 42 0.008 UniRef50_Q6N2Q3 Cluster: Probable transcriptional regulator, Crp... 42 0.008 UniRef50_Q2W0I8 Cluster: Kef-type K+ transport systems, predicte... 42 0.008 UniRef50_Q0VMY3 Cluster: CAMP-dependent protein kinase regulator... 42 0.008 UniRef50_Q04S82 Cluster: CAMP-dependent protein kinase; n=4; Lep... 42 0.008 UniRef50_A0P0J2 Cluster: Putative catabolite gene activator; n=2... 42 0.008 UniRef50_Q22BB2 Cluster: Cyclic nucleotide-binding domain contai... 42 0.008 UniRef50_A7SLM9 Cluster: Predicted protein; n=2; Nematostella ve... 42 0.008 UniRef50_A0DFJ4 Cluster: Chromosome undetermined scaffold_49, wh... 42 0.008 UniRef50_A0CUC4 Cluster: Chromosome undetermined scaffold_28, wh... 42 0.008 UniRef50_UPI00006CE543 Cluster: cyclic nucleotide-binding domain... 42 0.011 UniRef50_Q4RYB3 Cluster: Chromosome 3 SCAF14978, whole genome sh... 42 0.011 UniRef50_Q9ER33 Cluster: Cyclic nucleotide-gated channel 2b; n=9... 42 0.011 UniRef50_Q8YY17 Cluster: Transcriptional regulator; n=6; Cyanoba... 42 0.011 UniRef50_Q7MRZ8 Cluster: DNR; n=1; Wolinella succinogenes|Rep: D... 42 0.011 UniRef50_Q2S0L0 Cluster: Transcription regulator, Crp family, pu... 42 0.011 UniRef50_P74678 Cluster: DNR protein; n=1; Synechocystis sp. PCC... 42 0.011 UniRef50_A4U0N5 Cluster: Transcriptional regulator, Crp/Fnr fami... 42 0.011 UniRef50_P90975 Cluster: Cyclic nucleotide-gated channel; n=3; C... 42 0.011 UniRef50_Q16281 Cluster: Cyclic nucleotide-gated cation channel ... 42 0.011 UniRef50_Q64359 Cluster: Cyclic nucleotide-gated olfactory chann... 42 0.011 UniRef50_UPI0000F1EF31 Cluster: PREDICTED: similar to cyclic nuc... 41 0.014 UniRef50_UPI00006CC101 Cluster: cyclic nucleotide-binding domain... 41 0.014 UniRef50_UPI00006CB774 Cluster: cyclic nucleotide-binding domain... 41 0.014 UniRef50_Q3AF29 Cluster: Transcriptional regulator, Crp/Fnr fami... 41 0.014 UniRef50_Q2JXE2 Cluster: Cyclic nucleotide-binding protein, trun... 41 0.014 UniRef50_Q1N3Q3 Cluster: Putative uncharacterized protein; n=1; ... 41 0.014 UniRef50_Q01YJ3 Cluster: Cyclic nucleotide-binding protein precu... 41 0.014 UniRef50_A5UY24 Cluster: Cyclic nucleotide-binding protein; n=2;... 41 0.014 UniRef50_A1ZHX6 Cluster: Serine/threonine protein kinases; n=1; ... 41 0.014 UniRef50_A1B7P5 Cluster: Putative transcriptional regulator, Crp... 41 0.014 UniRef50_A0NR38 Cluster: Putative Na+/H+ antiporter with cyclic ... 41 0.014 UniRef50_Q23YQ2 Cluster: Cyclic nucleotide-binding domain contai... 41 0.014 UniRef50_A0CUS7 Cluster: Chromosome undetermined scaffold_28, wh... 41 0.014 UniRef50_UPI00006D001D Cluster: cation channel family protein; n... 41 0.019 UniRef50_UPI00006CC00D Cluster: hypothetical protein TTHERM_0041... 41 0.019 UniRef50_Q3I0N1 Cluster: Cyclic nucleotide-gated channel beta co... 41 0.019 UniRef50_Q8EY25 Cluster: Cyclic nucleotide dependent protein kin... 41 0.019 UniRef50_Q2AEB9 Cluster: Cyclic nucleotide-binding:Bacterial reg... 41 0.019 UniRef50_Q0LIK4 Cluster: MscS Mechanosensitive ion channel; n=1;... 41 0.019 UniRef50_Q08UL3 Cluster: TrkA-N domain family; n=1; Stigmatella ... 41 0.019 UniRef50_A5PA10 Cluster: Cyclic nucleotide-binding protein; n=1;... 41 0.019 UniRef50_A0NP85 Cluster: Cyclic nucleotide-binding domain (CNMP-... 41 0.019 UniRef50_A5K155 Cluster: Putative uncharacterized protein; n=4; ... 41 0.019 UniRef50_P34578 Cluster: Uncharacterized protein T20G5.5; n=2; C... 41 0.019 UniRef50_UPI0000D56485 Cluster: PREDICTED: similar to Potassium/... 40 0.024 UniRef50_UPI00006CF9CA Cluster: cation channel family protein; n... 40 0.024 UniRef50_Q4SKD5 Cluster: Chromosome 13 SCAF14566, whole genome s... 40 0.024 UniRef50_Q72VQ9 Cluster: Cyclic nucleotide binding protein; n=4;... 40 0.024 UniRef50_Q2N5Y8 Cluster: Cyclic nucleotide-binding; n=1; Erythro... 40 0.024 UniRef50_Q1ETT3 Cluster: Cyclic nucleotide-binding:regulatory pr... 40 0.024 UniRef50_Q0EX27 Cluster: Cyclic nucleotide-binding:Bacterial reg... 40 0.024 UniRef50_A6GAV1 Cluster: Protein phosphatase/cyclic nucleotide-b... 40 0.024 UniRef50_A0LNW4 Cluster: Transcriptional regulator, Crp/Fnr fami... 40 0.024 UniRef50_Q45ZY2 Cluster: Hyperpolarization-gated and cyclic nucl... 40 0.024 UniRef50_Q23S28 Cluster: Cyclic nucleotide-binding domain contai... 40 0.024 UniRef50_Q23AA7 Cluster: Cation channel family protein; n=1; Tet... 40 0.024 UniRef50_A7RGK0 Cluster: Predicted protein; n=1; Nematostella ve... 40 0.024 UniRef50_Q6BWV4 Cluster: Debaryomyces hansenii chromosome B of s... 40 0.024 UniRef50_UPI000065F344 Cluster: Cyclic nucleotide-gated olfactor... 40 0.032 UniRef50_Q4T9V2 Cluster: Chromosome undetermined SCAF7488, whole... 40 0.032 UniRef50_Q3M891 Cluster: Transcriptional Regulator, Crp/Fnr fami... 40 0.032 UniRef50_A6G6X5 Cluster: Predicted signal transduction protein c... 40 0.032 UniRef50_A4LZF2 Cluster: Cyclic nucleotide-binding protein; n=2;... 40 0.032 UniRef50_A4BIJ9 Cluster: Transcriptional regulator Dnr; n=1; Rei... 40 0.032 UniRef50_A2SMH7 Cluster: CAMP-dependent protein kinase-catabolit... 40 0.032 UniRef50_A0L8L8 Cluster: Cyclic nucleotide-binding protein; n=1;... 40 0.032 UniRef50_A4S699 Cluster: Predicted protein; n=2; Ostreococcus|Re... 40 0.032 UniRef50_A7RFM7 Cluster: Predicted protein; n=1; Nematostella ve... 40 0.032 UniRef50_A0CLY8 Cluster: Chromosome undetermined scaffold_21, wh... 40 0.032 UniRef50_UPI00015BC926 Cluster: UPI00015BC926 related cluster; n... 40 0.043 UniRef50_UPI00006CFEE1 Cluster: cyclic nucleotide-binding domain... 40 0.043 UniRef50_UPI00006CA695 Cluster: cyclic nucleotide-binding domain... 40 0.043 UniRef50_Q2J6W1 Cluster: Transcriptional regulator, Crp/Fnr fami... 40 0.043 UniRef50_Q2G4A2 Cluster: Cyclic nucleotide-binding domain (CNMP-... 40 0.043 UniRef50_Q15QG5 Cluster: Transcriptional regulator, Crp/Fnr fami... 40 0.043 UniRef50_Q24278 Cluster: Cyclic nucleotide-gated cation channel;... 40 0.043 UniRef50_Q9CS95 Cluster: 8 days embryo whole body cDNA, RIKEN fu... 39 0.057 UniRef50_Q82GX1 Cluster: Putative transcriptional regulator with... 39 0.057 UniRef50_Q72T22 Cluster: Cyclic nucleotide binding patatin-like ... 39 0.057 UniRef50_Q47A56 Cluster: Cyclic nucleotide-binding; n=1; Dechlor... 39 0.057 UniRef50_Q076H6 Cluster: N-acyl phenylalanine synthase; n=1; unc... 39 0.057 UniRef50_A6G6N1 Cluster: Cyclic nucleotide-binding domain protei... 39 0.057 UniRef50_A0LQJ1 Cluster: Cyclic nucleotide-binding protein; n=1;... 39 0.057 UniRef50_Q01CK0 Cluster: Predicted esterase of the alpha-beta hy... 39 0.057 UniRef50_Q23R10 Cluster: Cation channel family protein; n=1; Tet... 39 0.057 UniRef50_Q23AA8 Cluster: Cation channel family protein; n=1; Tet... 39 0.057 UniRef50_Q237N2 Cluster: Cation channel family protein; n=1; Tet... 39 0.057 UniRef50_A0DV12 Cluster: Chromosome undetermined scaffold_65, wh... 39 0.057 UniRef50_Q14028 Cluster: Cyclic nucleotide-gated cation channel ... 39 0.057 UniRef50_UPI00006CE534 Cluster: cyclic nucleotide-binding domain... 39 0.075 UniRef50_UPI00006CE52D Cluster: cyclic nucleotide-binding domain... 39 0.075 UniRef50_Q82V15 Cluster: Cyclic nucleotide-binding domain:cAMP-d... 39 0.075 UniRef50_Q6MLB6 Cluster: Putative uncharacterized protein; n=1; ... 39 0.075 UniRef50_Q04QT5 Cluster: CAMP-binding protein; n=4; Leptospira|R... 39 0.075 UniRef50_Q03UH4 Cluster: Crp-like transcriptional regulator; n=2... 39 0.075 UniRef50_A7C611 Cluster: Cyclic nucleotide-binding; n=1; Beggiat... 39 0.075 UniRef50_Q9LKP2 Cluster: Putative potassium channel protein Kmt1... 39 0.075 UniRef50_A7STN1 Cluster: Predicted protein; n=2; Nematostella ve... 39 0.075 UniRef50_Q2HCN1 Cluster: Putative uncharacterized protein; n=1; ... 39 0.075 UniRef50_UPI0000D568C5 Cluster: PREDICTED: similar to sperm-spec... 38 0.099 UniRef50_Q1LXY6 Cluster: Novel protein similar to vertebrate cyc... 38 0.099 UniRef50_Q89W82 Cluster: Bll0811 protein; n=3; Bradyrhizobium|Re... 38 0.099 UniRef50_Q30QZ1 Cluster: Putative transcriptional regulator, Crp... 38 0.099 UniRef50_O83286 Cluster: Catabolite gene activator; n=2; Trepone... 38 0.099 UniRef50_A6NUW6 Cluster: Putative uncharacterized protein; n=1; ... 38 0.099 UniRef50_A4TXU7 Cluster: cAMP-binding protein-catabolite gene ac... 38 0.099 UniRef50_A4TW57 Cluster: cAMP-binding proteins-catabolite gene a... 38 0.099 UniRef50_A1ZRY9 Cluster: Transporter, small conductance mechanos... 38 0.099 UniRef50_A1IDX0 Cluster: Putative transcriptional regulator, Crp... 38 0.099 UniRef50_A0UXQ0 Cluster: Transcriptional regulator, Crp/Fnr fami... 38 0.099 UniRef50_Q93486 Cluster: Putative uncharacterized protein cng-1;... 38 0.099 UniRef50_Q23CM4 Cluster: Cyclic nucleotide-binding domain contai... 38 0.099 UniRef50_Q22TN5 Cluster: Cation channel family protein; n=2; Tet... 38 0.099 UniRef50_A0CB28 Cluster: Chromosome undetermined scaffold_163, w... 38 0.099 UniRef50_Q5KQ28 Cluster: Vacuole protein, putative; n=1; Filobas... 38 0.099 UniRef50_UPI0001509BB1 Cluster: cyclic nucleotide-binding domain... 38 0.13 UniRef50_UPI0000D56B62 Cluster: PREDICTED: similar to Potassium/... 38 0.13 UniRef50_Q98GN8 Cluster: Mll3241 protein; n=2; Rhizobiales|Rep: ... 38 0.13 UniRef50_Q5ZVB5 Cluster: CAAX amino terminal protease family pro... 38 0.13 UniRef50_Q1K2E6 Cluster: Cyclic nucleotide-binding protein; n=1;... 38 0.13 UniRef50_Q1EWQ8 Cluster: Cyclic nucleotide-binding:regulatory pr... 38 0.13 UniRef50_Q1D8V4 Cluster: Cyclic nucleotide-binding domain protei... 38 0.13 UniRef50_Q18WV6 Cluster: Transcriptional regulator, Crp/Fnr fami... 38 0.13 UniRef50_Q0PQI4 Cluster: Transcriptional regulator Crp/Fnr; n=1;... 38 0.13 UniRef50_A3YVU5 Cluster: Cyclic nucleotide-binding domain (CNMP-... 38 0.13 UniRef50_O97119 Cluster: Cyclic nucleotide-gated ion channel LCN... 38 0.13 UniRef50_A5DFW8 Cluster: Putative uncharacterized protein; n=1; ... 38 0.13 UniRef50_UPI00006CB8EE Cluster: cyclic nucleotide-binding domain... 38 0.17 UniRef50_Q4SKL1 Cluster: Chromosome undetermined SCAF14565, whol... 38 0.17 UniRef50_Q89HD2 Cluster: Bll6060 protein; n=3; Bradyrhizobium|Re... 38 0.17 UniRef50_Q7NIH1 Cluster: Glr2212 protein; n=2; Cyanobacteria|Rep... 38 0.17 UniRef50_Q6MIF1 Cluster: Probable cyclic nucleotide binding prot... 38 0.17 UniRef50_Q44026 Cluster: Orf2 protein; n=3; Cupriavidus|Rep: Orf... 38 0.17 UniRef50_Q21HQ8 Cluster: Cyclic nucleotide-binding; n=1; Sacchar... 38 0.17 UniRef50_Q0K1D5 Cluster: Transcriptional regulator CRP family; n... 38 0.17 UniRef50_Q0AWK5 Cluster: Putative uncharacterized protein; n=1; ... 38 0.17 UniRef50_A7HRV0 Cluster: Putative transcriptional regulator, Crp... 38 0.17 UniRef50_A7HF79 Cluster: Cyclic nucleotide-binding protein; n=1;... 38 0.17 UniRef50_A3VL67 Cluster: Putative uncharacterized protein; n=1; ... 38 0.17 UniRef50_A0NZG3 Cluster: CAMP-binding protein-catabolite gene ac... 38 0.17 UniRef50_Q06XL5 Cluster: Inwardly rectifying potassium channel A... 38 0.17 UniRef50_Q23AA5 Cluster: Cyclic nucleotide-binding domain contai... 38 0.17 UniRef50_A0BIM1 Cluster: Chromosome undetermined scaffold_11, wh... 38 0.17 UniRef50_UPI0000DB7A09 Cluster: PREDICTED: similar to CG8958-PA;... 37 0.23 UniRef50_UPI0000384142 Cluster: COG2199: FOG: GGDEF domain; n=1;... 37 0.23 UniRef50_Q8G502 Cluster: Probable transcriptional regulator with... 37 0.23 UniRef50_Q7WBP4 Cluster: Probable regulator; n=2; Bordetella|Rep... 37 0.23 UniRef50_Q74BP9 Cluster: Transcriptional regulator, Crp/Fnr fami... 37 0.23 UniRef50_Q2W0D8 Cluster: CAMP-binding protein-catabolite gene ac... 37 0.23 UniRef50_Q2SHS2 Cluster: CAMP-binding protein-catabolite gene ac... 37 0.23 UniRef50_Q1EMI3 Cluster: Putative ABC-type transport system, ATP... 37 0.23 UniRef50_Q0F204 Cluster: Cyclic nucleotide-binding protein; n=1;... 37 0.23 UniRef50_A7IGJ4 Cluster: Cyclic nucleotide-binding protein; n=1;... 37 0.23 UniRef50_A6KX98 Cluster: Putative regulatory protein; n=2; Bacte... 37 0.23 UniRef50_A1EWE7 Cluster: Conserved domain protein; n=5; Coxiella... 37 0.23 UniRef50_Q9W201 Cluster: CG3536-PA; n=3; Sophophora|Rep: CG3536-... 37 0.23 UniRef50_Q22U44 Cluster: Cyclic nucleotide-binding domain contai... 37 0.23 UniRef50_A0E296 Cluster: Chromosome undetermined scaffold_74, wh... 37 0.23 UniRef50_A0DME6 Cluster: Chromosome undetermined scaffold_56, wh... 37 0.23 UniRef50_A7EKJ1 Cluster: Putative uncharacterized protein; n=1; ... 37 0.23 UniRef50_Q9SJA4 Cluster: Probable cyclic nucleotide-gated ion ch... 37 0.23 UniRef50_UPI0000F21589 Cluster: PREDICTED: similar to 240K prote... 37 0.30 UniRef50_UPI00005890C6 Cluster: PREDICTED: similar to 240K prote... 37 0.30 UniRef50_Q6AL49 Cluster: Probable transcription regulator; n=1; ... 37 0.30 UniRef50_Q5LKQ8 Cluster: Cyclic nucleotide-binding protein; n=3;... 37 0.30 UniRef50_Q4ZZV6 Cluster: Cyclic nucleotide-binding; n=3; Pseudom... 37 0.30 UniRef50_A7C5Z1 Cluster: Putative uncharacterized protein; n=1; ... 37 0.30 UniRef50_Q6R6B4 Cluster: Putative uncharacterized protein; n=2; ... 37 0.30 UniRef50_Q22U43 Cluster: Cyclic nucleotide-binding domain contai... 37 0.30 UniRef50_A7TIE8 Cluster: Putative uncharacterized protein; n=1; ... 37 0.30 UniRef50_UPI0000D556B8 Cluster: PREDICTED: similar to cyclic nuc... 36 0.40 UniRef50_UPI0000384141 Cluster: COG0664: cAMP-binding proteins -... 36 0.40 UniRef50_UPI0000383B0E Cluster: COG0664: cAMP-binding proteins -... 36 0.40 UniRef50_Q4SDJ0 Cluster: Chromosome 18 SCAF14637, whole genome s... 36 0.40 UniRef50_Q5ZY24 Cluster: Putative uncharacterized protein; n=4; ... 36 0.40 UniRef50_Q2W4U7 Cluster: CAMP-binding protein-catabolite gene ac... 36 0.40 UniRef50_Q2AH01 Cluster: Cyclic nucleotide-binding:Bacterial reg... 36 0.40 UniRef50_Q1K454 Cluster: Cyclic nucleotide-binding protein; n=1;... 36 0.40 UniRef50_A7HBD8 Cluster: Putative uncharacterized protein; n=1; ... 36 0.40 UniRef50_A6G9I3 Cluster: Cyclic nucleotide-binding domain (CNMP-... 36 0.40 UniRef50_A4GJB6 Cluster: Possible cyclic nucleotide-binding/ion ... 36 0.40 UniRef50_A4B0Y5 Cluster: Cyclic nucleotide-binding protein; n=1;... 36 0.40 UniRef50_A3WV71 Cluster: Patatin; n=3; Nitrobacter|Rep: Patatin ... 36 0.40 UniRef50_Q236N7 Cluster: Cyclic nucleotide-binding domain contai... 36 0.40 UniRef50_Q6CWE3 Cluster: Similarities with ca|CA0961|IPF18822 Ca... 36 0.40 UniRef50_Q1DLC7 Cluster: Lysophospholipase NTE1; n=8; Pezizomyco... 36 0.40 UniRef50_UPI00006CFB0C Cluster: cyclic nucleotide-binding domain... 36 0.53 UniRef50_Q315Y2 Cluster: Cyclic nucleotide-binding domain (CNMP-... 36 0.53 UniRef50_Q21JY8 Cluster: Cyclic nucleotide-binding; n=1; Sacchar... 36 0.53 UniRef50_Q121L3 Cluster: Cyclic nucleotide-binding domain (CNMP-... 36 0.53 UniRef50_Q0LK35 Cluster: Cyclic nucleotide-binding; n=1; Herpeto... 36 0.53 UniRef50_P72309 Cluster: B protein; n=1; Rhodococcus opacus|Rep:... 36 0.53 UniRef50_A4EXU1 Cluster: Transcriptional activator FtrB; n=4; Rh... 36 0.53 UniRef50_A4A439 Cluster: Transcriptional regulatory protein; n=1... 36 0.53 UniRef50_A2DY06 Cluster: Cyclic nucleotide-binding domain contai... 36 0.53 UniRef50_A0D546 Cluster: Chromosome undetermined scaffold_38, wh... 36 0.53 UniRef50_UPI0000E4A0F9 Cluster: PREDICTED: similar to ENSANGP000... 36 0.70 UniRef50_Q12IK7 Cluster: Cyclic nucleotide-binding; n=1; Shewane... 36 0.70 UniRef50_Q0FXM0 Cluster: Putative catabolite gene activator; n=1... 36 0.70 UniRef50_A7HSM8 Cluster: Cyclic nucleotide-binding protein; n=1;... 36 0.70 UniRef50_A7HFA3 Cluster: Cyclic nucleotide-binding protein precu... 36 0.70 UniRef50_A5CYD6 Cluster: Hypothetical transcriptional regulator;... 36 0.70 UniRef50_A4TWD8 Cluster: MscS Mechanosensitive ion channel; n=1;... 36 0.70 UniRef50_A4SX00 Cluster: Cyclic nucleotide-binding protein; n=1;... 36 0.70 UniRef50_Q16TJ9 Cluster: Cyclic-nucleotide-gated cation channel;... 36 0.70 UniRef50_Q38898 Cluster: Potassium channel AKT2/3; n=6; core eud... 36 0.70 UniRef50_Q6MHS5 Cluster: Putative transcriptional regulator; n=1... 35 0.92 UniRef50_Q62HJ0 Cluster: Transcriptional regulator, putative; n=... 35 0.92 UniRef50_Q31RQ1 Cluster: Cyclic nucleotide-binding domain (CNMP-... 35 0.92 UniRef50_Q9X7J7 Cluster: DnrE protein; n=5; Pseudomonas stutzeri... 35 0.92 UniRef50_A5UWJ7 Cluster: Cyclic nucleotide-binding protein; n=3;... 35 0.92 UniRef50_A4BEG8 Cluster: Putative uncharacterized protein; n=1; ... 35 0.92 UniRef50_A0LQJ4 Cluster: Cyclic nucleotide-binding protein; n=1;... 35 0.92 UniRef50_A0KFI6 Cluster: Transporter, small conductance mechanos... 35 0.92 UniRef50_Q8VX27 Cluster: Inwardly rectifying potassium channel; ... 35 0.92 UniRef50_Q8ILS2 Cluster: Putative uncharacterized protein; n=2; ... 35 0.92 UniRef50_Q612C2 Cluster: Putative uncharacterized protein CBG168... 35 0.92 UniRef50_Q23AQ7 Cluster: Zinc knuckle family protein; n=1; Tetra... 35 0.92 UniRef50_A0DKI0 Cluster: Chromosome undetermined scaffold_54, wh... 35 0.92 UniRef50_A0BGS4 Cluster: Chromosome undetermined scaffold_106, w... 35 0.92 UniRef50_P46908 Cluster: Anaerobic regulatory protein; n=21; Bac... 35 0.92 UniRef50_UPI000150A51C Cluster: cyclic nucleotide-binding domain... 35 1.2 UniRef50_UPI00006CB136 Cluster: cation channel family protein; n... 35 1.2 UniRef50_Q893F0 Cluster: Transcriptional regulatory protein; n=1... 35 1.2 UniRef50_Q2P3K9 Cluster: Fumarate and nitrate reduction regulato... 35 1.2 UniRef50_Q2BRJ0 Cluster: Cyclic nucleotide-binding:Bacterial reg... 35 1.2 UniRef50_Q21SN7 Cluster: Transcriptional regulator, Crp/Fnr fami... 35 1.2 UniRef50_Q0LC35 Cluster: Stage II sporulation E; n=1; Herpetosip... 35 1.2 UniRef50_O68882 Cluster: CAMP-dependent protein kinase; n=10; Ps... 35 1.2 UniRef50_A4A8R0 Cluster: Protein containing Cyclic nucleotide-bi... 35 1.2 UniRef50_A2WVE6 Cluster: Putative uncharacterized protein; n=1; ... 35 1.2 UniRef50_Q23K40 Cluster: Cyclic nucleotide-binding domain contai... 35 1.2 UniRef50_A7RTA9 Cluster: Predicted protein; n=2; Nematostella ve... 35 1.2 UniRef50_A4VDK5 Cluster: Voltage and ligand gated potassium chan... 35 1.2 UniRef50_A0D4X5 Cluster: Chromosome undetermined scaffold_38, wh... 35 1.2 UniRef50_P0ACK1 Cluster: Catabolite gene activator; n=101; Gamma... 35 1.2 UniRef50_O65717 Cluster: Cyclic nucleotide-gated ion channel 1; ... 35 1.2 UniRef50_UPI000150A0A0 Cluster: cyclic nucleotide-binding domain... 34 1.6 UniRef50_UPI0000E48F05 Cluster: PREDICTED: similar to cGMP-depen... 34 1.6 UniRef50_Q89CE1 Cluster: Blr7856 protein; n=2; Bradyrhizobium|Re... 34 1.6 UniRef50_Q5P1U7 Cluster: Nnr-like transcriptional regulator, Crp... 34 1.6 UniRef50_Q2IIM5 Cluster: Cyclic nucleotide-binding domain (CNMP-... 34 1.6 UniRef50_Q53240 Cluster: Nitrite and nitric oxide reductase regu... 34 1.6 UniRef50_Q51661 Cluster: Fnr-like transcriptional activator; n=2... 34 1.6 UniRef50_Q18S66 Cluster: Transcriptional regulator, Crp/Fnr fami... 34 1.6 UniRef50_A6G9E4 Cluster: Cyclic nucleotide-binding domain (CNMP-... 34 1.6 UniRef50_A4B9S7 Cluster: Cyclic nucleotide-binding (CNMP-BD) pro... 34 1.6 >UniRef50_Q7PPI8 Cluster: ENSANGP00000022232; n=3; Endopterygota|Rep: ENSANGP00000022232 - Anopheles gambiae str. PEST Length = 381 Score = 203 bits (496), Expect = 2e-51 Identities = 94/145 (64%), Positives = 120/145 (82%) Frame = +2 Query: 17 KPPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQ 196 KP V R+ +RRKSVFAETYDPE DD DEGA A+FPK+D QRARL ++V+ ILLFRSLD + Sbjct: 75 KPLVNRYASRRKSVFAETYDPENDDEDEGARAIFPKTDEQRARLCDSVKNILLFRSLDKE 134 Query: 197 QMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS 376 QM +VLDAMFEK + +Y+I+QGDDGDNFYVIE+G+++ V G+D +K +HTY+ GS Sbjct: 135 QMNEVLDAMFEKIVQAKDYIIKQGDDGDNFYVIESGIYNAYV-GED--QKHIHTYDNRGS 191 Query: 377 FGELALMYNMPRAASVRAQTAGALW 451 FGELAL+YNMPRAA+++A+T G LW Sbjct: 192 FGELALLYNMPRAATIQAETDGKLW 216 Score = 57.2 bits (132), Expect = 2e-07 Identities = 33/104 (31%), Positives = 55/104 (52%), Gaps = 1/104 (0%) Frame = +2 Query: 122 KSDAQRARLAEAVR-GILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIE 298 KS ++ ++ EA+ + + ++L + + DA+ + G+ +I+QGD D Y IE Sbjct: 229 KSAFRKRKMYEALLDAVPMLKTLQNYERMNLADALIPQTYAKGDRIIKQGDAADGMYFIE 288 Query: 299 NGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 430 +G + + D E + E G FGELAL+ + PRAAS A Sbjct: 289 DGKVSIRIQ-QDAGEVEISNLEKGGYFGELALVTHRPRAASAYA 331 >UniRef50_P81900 Cluster: cAMP-dependent protein kinase type II regulatory subunit; n=17; Eumetazoa|Rep: cAMP-dependent protein kinase type II regulatory subunit - Drosophila melanogaster (Fruit fly) Length = 377 Score = 196 bits (479), Expect = 2e-49 Identities = 91/145 (62%), Positives = 119/145 (82%) Frame = +2 Query: 17 KPPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQ 196 +PPV ++RRKSVFAE YDPE DD D+GA AVFPK+D QRARL E+V+ +LLFRSL+ + Sbjct: 73 EPPVMA-SSRRKSVFAEAYDPEADDDDDGATAVFPKTDEQRARLVESVKNVLLFRSLEKE 131 Query: 197 QMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS 376 QM QVLDAMFE++ +PG+++IRQGDDGDNFYVIE+GV+ V + +K ++TY +G Sbjct: 132 QMNQVLDAMFERKVQPGDFIIRQGDDGDNFYVIESGVYKVYIN-----DKHINTYNHTGL 186 Query: 377 FGELALMYNMPRAASVRAQTAGALW 451 FGELAL+YNMPRAA+V+A+T+G LW Sbjct: 187 FGELALLYNMPRAATVQAETSGLLW 211 Score = 62.1 bits (144), Expect = 7e-09 Identities = 36/105 (34%), Positives = 55/105 (52%) Frame = +2 Query: 134 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 313 +R E + + + ++L + + DA+ K + GE +I+QGD D Y IE G Sbjct: 229 KRKMYEELLNSVPMLKALQNYERMNLADALVSKSYDNGERIIKQGDAADGMYFIEEGTVS 288 Query: 314 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGAL 448 V + DD ++ +G FGELAL+ + PRAASV A T G + Sbjct: 289 VRMDQDDAEVEISQLGKGQ-YFGELALVTHRPRAASVYA-TGGVV 331 >UniRef50_Q5DI18 Cluster: SJCHGC02266 protein; n=1; Schistosoma japonicum|Rep: SJCHGC02266 protein - Schistosoma japonicum (Blood fluke) Length = 377 Score = 167 bits (407), Expect = 1e-40 Identities = 81/138 (58%), Positives = 100/138 (72%), Gaps = 1/138 (0%) Frame = +2 Query: 41 NRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDA 220 +RR V AE+YDPE+DDS V PK++ QR RL +A + ILLFR LD QM+ V+DA Sbjct: 74 SRRAGVAAESYDPEKDDSSSAVKVVHPKTEEQRQRLTQATKDILLFRCLDDDQMKDVIDA 133 Query: 221 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV-TGDDRVEKVVHTYEGSGSFGELALM 397 MFE+ PGE VI G+DGDNFYVIE GV+D++V GD+ EKVV Y+ GSFGELALM Sbjct: 134 MFERHVSPGEKVITLGEDGDNFYVIEKGVYDIIVKVGDE--EKVVGKYDNKGSFGELALM 191 Query: 398 YNMPRAASVRAQTAGALW 451 YN PRAA++ A+T G LW Sbjct: 192 YNTPRAATILAKTEGVLW 209 Score = 64.5 bits (150), Expect = 1e-09 Identities = 37/107 (34%), Positives = 54/107 (50%), Gaps = 1/107 (0%) Frame = +2 Query: 113 VFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYV 292 V K+ +R E + + + SL A + + DA+ K E E +I+QGD GD + Sbjct: 220 VLKKAFEKRRLYEELLNQVPILESLSAYERMSIADALRTKIFEANEQIIKQGDPGDEMFF 279 Query: 293 IENGVFDV-LVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 430 +E G + + + EK V E G FGELAL+ + PRAAS A Sbjct: 280 VEEGKVSIKMKRSGETEEKEVAVIEKGGYFGELALLTSHPRAASAYA 326 >UniRef50_P31323 Cluster: cAMP-dependent protein kinase type II-beta regulatory subunit; n=56; Deuterostomia|Rep: cAMP-dependent protein kinase type II-beta regulatory subunit - Homo sapiens (Human) Length = 418 Score = 167 bits (406), Expect = 1e-40 Identities = 83/145 (57%), Positives = 104/145 (71%) Frame = +2 Query: 20 PPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQ 199 P + RF RR SV AE Y+P+E++ D + + PK+D QR RL EA + ILLF++LD +Q Sbjct: 104 PVINRFT-RRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQ 162 Query: 200 MQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF 379 M QVLDAMFEK + GE+VI QGDDGDNFYVI+ G FD+ V D V + V Y+ GSF Sbjct: 163 MSQVLDAMFEKLVKDGEHVIDQGDDGDNFYVIDRGTFDIYVKCDG-VGRCVGNYDNRGSF 221 Query: 380 GELALMYNMPRAASVRAQTAGALWG 454 GELALMYN PRAA++ A + GALWG Sbjct: 222 GELALMYNTPRAATITATSPGALWG 246 Score = 56.8 bits (131), Expect = 3e-07 Identities = 36/113 (31%), Positives = 62/113 (54%), Gaps = 7/113 (6%) Frame = +2 Query: 113 VFPKSDAQRARLAEA-VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFY 289 + K++A++ ++ E+ + + +SL+ + +V+D + K GE +I QGD D+F+ Sbjct: 255 IIVKNNAKKRKMYESFIESLPFLKSLEFSERLKVVDVIGTKVYNDGEQIIAQGDSADSFF 314 Query: 290 VIENGVFDVLV--TGDDRVEK--VVHTYEGSGS--FGELALMYNMPRAASVRA 430 ++E+G + + G VE+ V S FGELAL+ N PRAAS A Sbjct: 315 IVESGEVKITMKRKGKSEVEENGAVEMPRCSRGQYFGELALVTNKPRAASAHA 367 >UniRef50_Q4RSC3 Cluster: Chromosome 13 SCAF15000, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 13 SCAF15000, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 422 Score = 162 bits (393), Expect = 5e-39 Identities = 80/144 (55%), Positives = 102/144 (70%) Frame = +2 Query: 20 PPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQ 199 P + RF+ RR SV AE ++P+ED+ ++ PK+D QR RL EA R ILLF++LD ++ Sbjct: 127 PVINRFS-RRASVCAEAFNPDEDEEEKEPLVTHPKTDEQRQRLQEACRDILLFKNLDPEE 185 Query: 200 MQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF 379 M QVLDAMFEK GE++I Q DDGDNFYVIE+G F + V D EK+V Y+ GSF Sbjct: 186 MSQVLDAMFEKFCTEGEHIIDQDDDGDNFYVIESGTFSIFVK-TDSTEKLVGCYDNRGSF 244 Query: 380 GELALMYNMPRAASVRAQTAGALW 451 GELALMYN PRAA++ A + GALW Sbjct: 245 GELALMYNTPRAATIIATSTGALW 268 >UniRef50_P31320 Cluster: cAMP-dependent protein kinase regulatory subunit; n=1; Blastocladiella emersonii|Rep: cAMP-dependent protein kinase regulatory subunit - Blastocladiella emersonii (Aquatic fungus) Length = 403 Score = 126 bits (304), Expect = 3e-28 Identities = 70/144 (48%), Positives = 82/144 (56%) Frame = +2 Query: 20 PPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQ 199 PPV RR SV AE+ P D D V PKSD QRAR+ ++ LFR+LD Q Sbjct: 107 PPVVN-RGRRTSVSAESMAPTAHDVD-AVKTVIPKSDEQRARIQASIGNNFLFRNLDEDQ 164 Query: 200 MQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF 379 V++AM EK+ GE VIRQG GD FYV+E G DV V + + V Y GSF Sbjct: 165 YTDVVNAMAEKKVAAGEVVIRQGGVGDYFYVVETGALDVFVNRNGNGDVKVTDYSAGGSF 224 Query: 380 GELALMYNMPRAASVRAQTAGALW 451 GELALMYN PRAA+V A LW Sbjct: 225 GELALMYNAPRAATVVATAESVLW 248 Score = 64.5 bits (150), Expect = 1e-09 Identities = 35/102 (34%), Positives = 58/102 (56%), Gaps = 1/102 (0%) Frame = +2 Query: 131 AQRARLAEA-VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGV 307 +++ R+ EA + + L SL+ + ++ DA+ G+ VIRQGD G+NFY+IE G Sbjct: 264 SRKRRMYEAFLEEVPLLSSLEPYERHKIADALESVAYADGDVVIRQGDVGENFYIIEAGD 323 Query: 308 FDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQ 433 +V+ ++ E FGELAL+ + PR A++RA+ Sbjct: 324 AEVIKIDENGEEHHFRPLHKGNYFGELALLSDKPRVATIRAK 365 >UniRef50_Q4TGP1 Cluster: Chromosome undetermined SCAF3574, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF3574, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 235 Score = 124 bits (299), Expect = 1e-27 Identities = 60/117 (51%), Positives = 80/117 (68%), Gaps = 1/117 (0%) Frame = +2 Query: 38 NNRRKSVFAETYDPEEDDSDEGAPAVF-PKSDAQRARLAEAVRGILLFRSLDAQQMQQVL 214 +NRR SV AE Y+P+ED+ ++ P V PK+D QR RL +A + ILLF++LD +Q ++L Sbjct: 89 SNRRVSVCAEAYNPDEDEDEDAEPRVVNPKTDEQRRRLKDACKHILLFKTLDQEQFSEIL 148 Query: 215 DAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGE 385 DAMFE +P +++I QGDDGDNFYVIE G FD+ V D V Y+ GSFGE Sbjct: 149 DAMFEVLVKPQQHIIDQGDDGDNFYVIEKGTFDIFVQ-KDGASLCVGKYDNKGSFGE 204 >UniRef50_A7RGJ3 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 390 Score = 119 bits (287), Expect = 3e-26 Identities = 62/136 (45%), Positives = 83/136 (61%) Frame = +2 Query: 44 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 223 RR SV E Y+P + A +PKS+ R RL + I +F+S Q+ +LDAM Sbjct: 88 RRDSVAGEVYEPVNSNC-VSAQRFYPKSEDARKRLENVIGNIFIFKSCGKDQINMMLDAM 146 Query: 224 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYN 403 +E+ E +IRQGD GDNFY+I+ G F+VL + EK + +G GSFGELALMYN Sbjct: 147 YERVVYQEETIIRQGDAGDNFYIIDEGEFEVLFETNGAQEK-LGRLKGPGSFGELALMYN 205 Query: 404 MPRAASVRAQTAGALW 451 PR+A++RA T G LW Sbjct: 206 CPRSATIRACTPGVLW 221 Score = 47.2 bits (107), Expect = 2e-04 Identities = 32/105 (30%), Positives = 50/105 (47%), Gaps = 2/105 (1%) Frame = +2 Query: 125 SDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG 304 ++ +R + I + L A + + DA+ E +IRQ D D Y IE+G Sbjct: 236 TERKRRHYETLLERIPVLSQLTAYERTSLADALTTSVYRDEECIIRQDDPADCLYFIESG 295 Query: 305 VFDVLV-TGDDRVE-KVVHTYEGSGSFGELALMYNMPRAASVRAQ 433 + ++ + DR + KV+ T FGELAL+ R ASV A+ Sbjct: 296 IVEISIRDSKDRSKVKVISTAGPGEYFGELALVNKTKRGASVHAK 340 >UniRef50_A7S513 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 373 Score = 116 bits (280), Expect = 2e-25 Identities = 60/144 (41%), Positives = 88/144 (61%), Gaps = 1/144 (0%) Frame = +2 Query: 23 PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQM 202 P+ + +RR +V AE Y+P E+ +D A PKS+ QR L + + + LF + + Sbjct: 75 PIIKGRSRRAAVSAEPYNPNEN-ADFKAK-FHPKSEEQRNHLKKKLLELWLFEKFHREDL 132 Query: 203 QQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKV-VHTYEGSGSF 379 +LD+MFEK+ P E +I+ GD+GDNFYVI G +DV + + VHT+ G+G F Sbjct: 133 DVILDSMFEKKVSPEEIIIKVGDEGDNFYVINTGEYDVFALDTNTGASIKVHTFNGTGMF 192 Query: 380 GELALMYNMPRAASVRAQTAGALW 451 GELALM+N R A++ A+T G LW Sbjct: 193 GELALMHNSLRNATIVAKTEGTLW 216 Score = 60.5 bits (140), Expect = 2e-08 Identities = 38/100 (38%), Positives = 55/100 (55%), Gaps = 1/100 (1%) Frame = +2 Query: 134 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDN-FYVIENGVF 310 +R R E ++ + + + L ++ +V DA++ K + GE VIR+G++ Y IE G Sbjct: 234 RRERNIELLKSVSILKELKPDELDKVSDALYPKEFKDGEAVIREGNESAYCMYFIEKGKV 293 Query: 311 DVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 430 V V D VEK V FGELAL+ N PR+ASV A Sbjct: 294 RVTVK-DGEVEKTVEF--DKNYFGELALVMNQPRSASVYA 330 >UniRef50_Q5DAR5 Cluster: SJCHGC05163 protein; n=1; Schistosoma japonicum|Rep: SJCHGC05163 protein - Schistosoma japonicum (Blood fluke) Length = 172 Score = 113 bits (272), Expect = 2e-24 Identities = 54/95 (56%), Positives = 73/95 (76%), Gaps = 2/95 (2%) Frame = +2 Query: 44 RRKSVFAETYDPEED--DSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLD 217 RR+SV AE++DPE+D D++E ++PKSD+QRARL AV+ ILLFR LD +Q +V+D Sbjct: 53 RRQSVAAESFDPEKDSDDNNEEERQIYPKSDSQRARLTNAVKEILLFRCLDEEQKSKVID 112 Query: 218 AMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV 322 AM E + + G+ VI QGDDGDNFYVIE+G +D+ V Sbjct: 113 AMQEMKVKQGDVVITQGDDGDNFYVIESGTYDIYV 147 >UniRef50_P10644 Cluster: cAMP-dependent protein kinase type I-alpha regulatory subunit; n=105; Eumetazoa|Rep: cAMP-dependent protein kinase type I-alpha regulatory subunit - Homo sapiens (Human) Length = 381 Score = 107 bits (257), Expect = 1e-22 Identities = 64/144 (44%), Positives = 81/144 (56%) Frame = +2 Query: 23 PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQM 202 PV + RR ++ AE Y E+D+ V PK A LA+A+ +LF LD + Sbjct: 89 PVVKGRRRRGAISAEVYT--EEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNER 146 Query: 203 QQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFG 382 + DAMF GE VI+QGD+GDNFYVI+ G DV V E EG GSFG Sbjct: 147 SDIFDAMFSVSFIAGETVIQQGDEGDNFYVIDQGETDVYVNN----EWATSVGEG-GSFG 201 Query: 383 ELALMYNMPRAASVRAQTAGALWG 454 ELAL+Y PRAA+V+A+T LWG Sbjct: 202 ELALIYGTPRAATVKAKTNVKLWG 225 Score = 55.6 bits (128), Expect = 6e-07 Identities = 35/101 (34%), Positives = 53/101 (52%), Gaps = 1/101 (0%) Frame = +2 Query: 134 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 313 +R E + + + SLD + V DA+ + E G+ ++ QG+ GD F++I G Sbjct: 242 KRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAA 301 Query: 314 VLVTGDDRVEKV-VHTYEGSGSFGELALMYNMPRAASVRAQ 433 VL + E V V S FGE+AL+ N PRAA+V A+ Sbjct: 302 VLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVAR 342 >UniRef50_A6SCU8 Cluster: Putative uncharacterized protein; n=2; Sclerotiniaceae|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 468 Score = 106 bits (254), Expect = 3e-22 Identities = 67/145 (46%), Positives = 82/145 (56%), Gaps = 9/145 (6%) Frame = +2 Query: 44 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 223 RR SV AE+ +P +D +P K+ Q ARL +++ G LF LD +Q QVL A+ Sbjct: 169 RRTSVSAESLNPTASSNDNWSPPFHQKTQDQVARLKKSISGNFLFSHLDDEQSAQVLGAL 228 Query: 224 FEKR-SEPGEYVIRQGDDGDNFYVIENGVFDV-------LVTGDDRVEKVVHTYEGSGSF 379 EK G VI QGD GD FYV+E G FDV L G D + V T E GSF Sbjct: 229 VEKPIPAVGIKVISQGDQGDFFYVVEKGSFDVHVNSTGSLQPGPDGLGTKVATIEPGGSF 288 Query: 380 GELALMYNMPRAASV-RAQTAGALW 451 GELALMYN PRAA+V A+ + LW Sbjct: 289 GELALMYNAPRAATVISAEASCTLW 313 Score = 62.5 bits (145), Expect = 5e-09 Identities = 37/105 (35%), Positives = 59/105 (56%), Gaps = 1/105 (0%) Frame = +2 Query: 125 SDAQRARLAEA-VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 301 S QR RL E+ + + L +L + ++ DA+ ++ PG +I +GD G+ FY++E+ Sbjct: 327 STFQRRRLYESFLEEVPLLSTLTRYERSKIADALETQKYPPGTAIINEGDAGEAFYLLES 386 Query: 302 GVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 G + G V+ V Y FGELAL+ + PRAASV ++T Sbjct: 387 GEAEAYKRG---VDNPVKLYHKGDYFGELALLNDAPRAASVVSKT 428 >UniRef50_Q86ZN7 Cluster: cAMP-dependent protein kinase regulatory subunit; n=23; Pezizomycotina|Rep: cAMP-dependent protein kinase regulatory subunit - Trichoderma atroviride (Hypocrea atroviridis) Length = 462 Score = 104 bits (250), Expect = 1e-21 Identities = 67/151 (44%), Positives = 83/151 (54%), Gaps = 10/151 (6%) Frame = +2 Query: 29 ARFN-NRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQ 205 A++N +RR SV AE+ P D D P K+ Q RL A+ G LF LD +Q Sbjct: 155 AQYNFSRRTSVSAESLKPSADGFDNWTPPYTDKTPEQVERLKYAIEGNFLFSHLDDEQSA 214 Query: 206 QVLDAMFEKRSEP-GEYVIRQGDDGDNFYVIENGVFDVLVT-------GDDRVEKVVHTY 361 Q+L A+ EK G VI QGD GD FYV+E G FDV V G D + V T Sbjct: 215 QILGALVEKPIPARGIKVISQGDAGDYFYVVERGSFDVYVNDCGFIEPGPDGLGNKVGTI 274 Query: 362 EGSGSFGELALMYNMPRAAS-VRAQTAGALW 451 + GSFGELALMYN PRAA+ + A+ + LW Sbjct: 275 QAGGSFGELALMYNAPRAATIISAEGSCTLW 305 Score = 56.0 bits (129), Expect = 5e-07 Identities = 32/100 (32%), Positives = 55/100 (55%) Frame = +2 Query: 131 AQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVF 310 A+R + + + SL + ++ DA+ ++ PG+ +I +GD G +FY++E+G Sbjct: 322 ARRRMYENFLEEVPILSSLTPYERSKISDALETQKFAPGDVIIHEGDPGHSFYLLESGEA 381 Query: 311 DVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 430 + E+ V +Y+ FGELAL+ + PRAASV A Sbjct: 382 AAF-----KGEEQVLSYKKGDFFGELALLNDAPRAASVIA 416 >UniRef50_Q5H7P2 Cluster: CAMP-dependent protein kinase regulatory subunit; n=1; Aspergillus oryzae|Rep: CAMP-dependent protein kinase regulatory subunit - Aspergillus oryzae Length = 416 Score = 104 bits (249), Expect = 1e-21 Identities = 64/145 (44%), Positives = 80/145 (55%), Gaps = 9/145 (6%) Frame = +2 Query: 44 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 223 RR SV AE+ +P SD P PK++ Q +RL AV G LF LD Q + V+DA+ Sbjct: 119 RRTSVSAESLNPTSAGSDSWVPPHHPKTEEQVSRLKTAVSGNFLFSHLDDDQFKTVVDAL 178 Query: 224 FEKR-SEPGEYVIRQGDDGDNFYVIENGVFDVLV-------TGDDRVEKVVHTYEGSGSF 379 EK G VI QGD GD FY++E+G FDV + +G D + T GSF Sbjct: 179 VEKPIPAKGIKVISQGDAGDYFYIVEDGHFDVYIHPSGSVQSGSDGMGSKAGTIGPGGSF 238 Query: 380 GELALMYNMPRAAS-VRAQTAGALW 451 GELALMYN PRAA+ V + LW Sbjct: 239 GELALMYNAPRAATIVSTDSKSTLW 263 Score = 65.7 bits (153), Expect = 6e-10 Identities = 37/102 (36%), Positives = 60/102 (58%), Gaps = 1/102 (0%) Frame = +2 Query: 134 QRARLAEA-VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVF 310 QR R+ EA + + L SL + ++ DA+ + G +I++GD GD FY++E+G Sbjct: 280 QRRRMYEAFLEEVPLLSSLKPYERSKIADALDAIKFPAGSSIIKEGDPGDAFYLLESGEA 339 Query: 311 DVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 + G V++ V +Y+ FGELAL+ + PRAAS+ A+T Sbjct: 340 EAFKEG---VDRPVKSYQRGDYFGELALLDDQPRAASIVAKT 378 >UniRef50_Q9HFV9 Cluster: CAMP dependent protein kinase regulatory subunit; n=3; Filobasidiella neoformans|Rep: CAMP dependent protein kinase regulatory subunit - Cryptococcus neoformans var. neoformans Length = 482 Score = 101 bits (242), Expect = 9e-21 Identities = 64/140 (45%), Positives = 84/140 (60%), Gaps = 16/140 (11%) Frame = +2 Query: 80 EEDDS----DEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPG 247 EED++ + G P VFPKS+ Q AR+ +A++ LFR+LD +Q VL AM E + + G Sbjct: 185 EEDENTVNLNSGTP-VFPKSEEQLARIRQAIKPNFLFRNLDDEQEADVLAAMKEVKVDAG 243 Query: 248 EYVIRQGDDGDNFYVIENGVFDVLVTGDDRV------------EKVVHTYEGSGSFGELA 391 E VI QG GD FY++ENG DV V + +V +KV EGS SFGELA Sbjct: 244 EVVIEQGAAGDFFYIVENGRLDVFVNKEGQVLDLEKGDRQGLGKKVAECSEGS-SFGELA 302 Query: 392 LMYNMPRAASVRAQTAGALW 451 LM+N PRAAS+ + T LW Sbjct: 303 LMHNAPRAASIISLTPCTLW 322 Score = 62.5 bits (145), Expect = 5e-09 Identities = 36/102 (35%), Positives = 57/102 (55%), Gaps = 1/102 (0%) Frame = +2 Query: 131 AQRARLAEA-VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGV 307 +++ RL E+ + + + SL Q+ ++ D + + GE VIRQGD GD F++IE+G Sbjct: 338 SRKRRLYESFLSEVPILASLQPQERAKIADVLESRTYNEGEDVIRQGDAGDEFFLIESGN 397 Query: 308 FDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQ 433 + T +D VV FGELAL+ RAA++RA+ Sbjct: 398 AMAIKTDEDGNASVVKHLGQGEYFGELALLNRRTRAATIRAE 439 >UniRef50_Q240X5 Cluster: Cyclic nucleotide-binding domain containing protein; n=2; Eukaryota|Rep: Cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 414 Score = 96.7 bits (230), Expect = 3e-19 Identities = 50/136 (36%), Positives = 79/136 (58%), Gaps = 1/136 (0%) Frame = +2 Query: 47 RKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMF 226 R SV AE Y + P V K + Q+ R+ + +F++LD ++ + V++AM Sbjct: 120 RASVSAEAYG-SFNKKGSYVPKVVHKEEEQKKRIEHRLMQAFMFQALDEKEREIVVNAMT 178 Query: 227 EKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT-GDDRVEKVVHTYEGSGSFGELALMYN 403 E + PG+++I+QG+DGDN YV++ G D D + + TY +FGELAL+YN Sbjct: 179 EVKFSPGDWIIKQGEDGDNLYVVDQGELDCYKKFSKDAEDTYLKTYMPGEAFGELALLYN 238 Query: 404 MPRAASVRAQTAGALW 451 PRAAS++A+T L+ Sbjct: 239 APRAASIKAKTDSILF 254 Score = 66.9 bits (156), Expect = 2e-10 Identities = 36/101 (35%), Positives = 59/101 (58%) Frame = +2 Query: 134 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 313 +R R + ++ + L S+D + + D + + + + GEYVIR+G++G FY+IE G Sbjct: 272 RRERFEQTLQKVELLDSMDPYERVHLADGIRDIKHKAGEYVIREGEEGKYFYMIEEGQLK 331 Query: 314 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 T ++ E V+ Y+ FGELAL+ N+PR A+V A T Sbjct: 332 ATKT-ENGHEVQVYEYKEGDYFGELALVKNIPRQANVIATT 371 >UniRef50_Q9HEW1 Cluster: cAMP-dependent protein kinase regulatory subunit; n=8; Saccharomycetales|Rep: cAMP-dependent protein kinase regulatory subunit - Candida albicans (Yeast) Length = 459 Score = 95.9 bits (228), Expect = 5e-19 Identities = 61/145 (42%), Positives = 77/145 (53%) Frame = +2 Query: 17 KPPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQ 196 K PVA NRR SV AE +P + D P V S + LA ++ LF+ LDA Sbjct: 168 KIPVAFNANRRTSVSAEALNPAKLKLDSWKPPVNNLSITEEETLANNLKNNFLFKQLDAN 227 Query: 197 QMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS 376 + V+ A+ +K +I+QGD+GD FY+IE G D V KV + EGS S Sbjct: 228 SKKTVIAALQQKSFAKDTVIIQQGDEGDFFYIIETGTVDFYVND----AKVSSSSEGS-S 282 Query: 377 FGELALMYNMPRAASVRAQTAGALW 451 FGELALMYN PRAA+ A T W Sbjct: 283 FGELALMYNSPRAATAVAATDVVCW 307 Score = 51.6 bits (118), Expect = 1e-05 Identities = 28/99 (28%), Positives = 56/99 (56%) Frame = +2 Query: 134 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 313 +R + ++ I + +SL ++ DA+ + G+ ++ +G+ G+NFY+IE+G Sbjct: 325 KRLMYEDFLKDIEVLKSLSDHARSKLADALSTEMYHKGDKIVTEGEQGENFYLIESGNCQ 384 Query: 314 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 430 V ++++ + +G FGELAL+ ++PR A+V A Sbjct: 385 VY---NEKLGNIKQLTKGD-YFGELALIKDLPRQATVEA 419 >UniRef50_Q9BMY7 Cluster: CAMP-dependent protein kinase regulatory subunit; n=1; Toxoplasma gondii|Rep: CAMP-dependent protein kinase regulatory subunit - Toxoplasma gondii Length = 385 Score = 94.7 bits (225), Expect = 1e-18 Identities = 54/136 (39%), Positives = 75/136 (55%), Gaps = 1/136 (0%) Frame = +2 Query: 47 RKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMF 226 R+SV AE Y AP V+PK+ Q+ R+ + + LF SLD + ++ V++A Sbjct: 92 RQSVSAEAYGEWNKRKKFVAP-VYPKTAEQKERITKVIESSFLFSSLDIEDLETVINAFQ 150 Query: 227 EKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT-GDDRVEKVVHTYEGSGSFGELALMYN 403 E + G +IRQGDDGD Y+IE G DV+ ++ K + +FGELALMYN Sbjct: 151 EVSVKKGTVIIRQGDDGDRLYLIETGEVDVMKKFPGEKENKFLCKMHPGDAFGELALMYN 210 Query: 404 MPRAASVRAQTAGALW 451 PRAA+V A LW Sbjct: 211 APRAATVIAADDMLLW 226 Score = 63.7 bits (148), Expect = 2e-09 Identities = 34/116 (29%), Positives = 63/116 (54%) Frame = +2 Query: 89 DSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQG 268 D D V + +R E+++ + + +D + ++ DA+ E G+ +I++G Sbjct: 229 DRDSFTNIVRDAAAKKREIFEESLKEVRILEDMDPYERSKLSDALRTATYEDGDVIIKEG 288 Query: 269 DDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 + GD FY++ G + + + +KVV Y+ G FGELAL+ + PRAA+V A++ Sbjct: 289 ETGDTFYILLEGAAEAI-----KNDKVVMEYKKGGFFGELALLKDQPRAATVVAKS 339 >UniRef50_Q22NC5 Cluster: Cyclic nucleotide-binding domain containing protein; n=5; Oligohymenophorea|Rep: Cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 381 Score = 94.7 bits (225), Expect = 1e-18 Identities = 50/130 (38%), Positives = 79/130 (60%) Frame = +2 Query: 47 RKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMF 226 R SV AE Y S A + PK+ Q R+ + + +F+SLD + + V+ AM Sbjct: 94 RTSVSAEAYGQYNQKSAFVAKNI-PKNANQVLRIKQRLSQAFMFQSLDENEQRVVIGAME 152 Query: 227 EKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNM 406 EK+ + GE +I+QGDDGD YV+++G+ D ++ + ++ TY+ +FGELAL+YN Sbjct: 153 EKKFKAGETIIKQGDDGDELYVVDSGLLDCYKEKANQEKILLKTYKEGEAFGELALLYNA 212 Query: 407 PRAASVRAQT 436 PRAA++ A+T Sbjct: 213 PRAATIIAKT 222 Score = 56.4 bits (130), Expect = 3e-07 Identities = 26/80 (32%), Positives = 51/80 (63%), Gaps = 3/80 (3%) Frame = +2 Query: 206 QVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGV---FDVLVTGDDRVEKVVHTYEGSGS 376 Q+ DA+ + G+Y++++G++G++F+++E G+ V+ G V+ V+ Y+ Sbjct: 269 QIADALHSHKFSKGDYIVKEGENGNSFFILEEGIAVATKVMQAGQAPVK--VYEYKSGDY 326 Query: 377 FGELALMYNMPRAASVRAQT 436 FGE+AL+ N RAA+V A++ Sbjct: 327 FGEIALLKNQTRAANVIAES 346 >UniRef50_P07278 Cluster: cAMP-dependent protein kinase regulatory subunit; n=6; Saccharomycetales|Rep: cAMP-dependent protein kinase regulatory subunit - Saccharomyces cerevisiae (Baker's yeast) Length = 416 Score = 94.3 bits (224), Expect = 1e-18 Identities = 62/147 (42%), Positives = 83/147 (56%), Gaps = 3/147 (2%) Frame = +2 Query: 20 PPVA-RFN-NRRKSVFAETYDPEEDDSDEGAPAVFP-KSDAQRARLAEAVRGILLFRSLD 190 PP+ FN RR SV ET P ++ D+ P + KS+ Q RL +++R LF LD Sbjct: 132 PPLPMHFNAQRRTSVSGETLQP--NNFDDWTPDHYKEKSEQQLQRLEKSIRNNFLFNKLD 189 Query: 191 AQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGS 370 + + V++ + EK G +I+QGD GD FYV+E G D V + KV + GS Sbjct: 190 SDSKRLVINCLEEKSVPKGATIIKQGDQGDYFYVVEKGTVDFYVNDN----KVNSSGPGS 245 Query: 371 GSFGELALMYNMPRAASVRAQTAGALW 451 SFGELALMYN PRAA+V A + LW Sbjct: 246 -SFGELALMYNSPRAATVVATSDCLLW 271 Score = 65.7 bits (153), Expect = 6e-10 Identities = 36/100 (36%), Positives = 58/100 (58%), Gaps = 1/100 (1%) Frame = +2 Query: 134 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 313 +R + ++ + + +SL ++ DA+ K +PGE +IR+GD G+NFY+IE G D Sbjct: 289 KRLMYDDLLKSMPVLKSLTTYDRAKLADALDTKIYQPGETIIREGDQGENFYLIEYGAVD 348 Query: 314 VLVTGDDRVEKVV-HTYEGSGSFGELALMYNMPRAASVRA 430 V G + K+ H Y FGE+AL+ ++PR A+V A Sbjct: 349 VSKKGQGVINKLKDHDY-----FGEVALLNDLPRQATVTA 383 >UniRef50_Q7KQK0 Cluster: CAMP-dependent protein kinase regulatory subunit, putative; n=7; Plasmodium|Rep: CAMP-dependent protein kinase regulatory subunit, putative - Plasmodium falciparum (isolate 3D7) Length = 441 Score = 93.5 bits (222), Expect = 2e-18 Identities = 47/136 (34%), Positives = 76/136 (55%) Frame = +2 Query: 44 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 223 +R SV AE Y D P V+ K + ++A++ EA+ LF L+ ++ + +++A Sbjct: 146 KRLSVSAEAYGDWNKKIDNFIPKVYKKDEKEKAKIREALNESFLFNHLNKKEFEIIVNAF 205 Query: 224 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYN 403 F+K E G +I +GD GD YVI+ G ++ T ++ ++V+ + FGELAL+YN Sbjct: 206 FDKNVEKGVNIINEGDYGDLLYVIDQGEVEIYKTKENNKKEVLTVLKSKDVFGELALLYN 265 Query: 404 MPRAASVRAQTAGALW 451 RAA+ A T LW Sbjct: 266 SKRAATATALTKCHLW 281 Score = 62.9 bits (146), Expect = 4e-09 Identities = 31/100 (31%), Positives = 59/100 (59%) Frame = +2 Query: 134 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 313 +R + + + + + +D + +V D + K GE +I++G++GD F+++ +G + Sbjct: 299 KRKMYEDILSHVNILKDMDPYERCKVADCLKSKSYNDGEIIIKEGEEGDTFFILIDG--N 356 Query: 314 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQ 433 + + D+ KV+ TY FGELAL+ N PRAA+++AQ Sbjct: 357 AVASKDN---KVIKTYTKGDYFGELALLKNKPRAATIKAQ 393 >UniRef50_A0DZ01 Cluster: Chromosome undetermined scaffold_7, whole genome shotgun sequence; n=7; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_7, whole genome shotgun sequence - Paramecium tetraurelia Length = 377 Score = 92.3 bits (219), Expect = 6e-18 Identities = 52/147 (35%), Positives = 82/147 (55%), Gaps = 1/147 (0%) Frame = +2 Query: 14 KKPPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDA 193 K+P AR +R S+ AE Y + + + P V K+ Q+ ++ + + +F SLD Sbjct: 73 KRPAAAR--KQRASISAEAYG-QYNRKESFQPRVIVKTQQQKEKIGKRLEQSFMFASLDQ 129 Query: 194 QQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT-GDDRVEKVVHTYEGS 370 ++ V+DAM E+ ++VI+QGD+GDN YV++ G + D K + Y Sbjct: 130 REKDIVIDAMEERSYNAEDWVIQQGDNGDNLYVVDQGELNCYKRFTKDGENKFLKVYYPG 189 Query: 371 GSFGELALMYNMPRAASVRAQTAGALW 451 SFGELAL+YN PRAAS++ +T L+ Sbjct: 190 ESFGELALLYNAPRAASIQCKTNSILF 216 Score = 66.5 bits (155), Expect = 3e-10 Identities = 38/104 (36%), Positives = 59/104 (56%), Gaps = 3/104 (2%) Frame = +2 Query: 134 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG--- 304 +R + ++ I L +D + V DA+ + G+YVIR+G+ GD FY+IE+G Sbjct: 234 KREKYVNVLKQIELLSMMDPYERSHVADAIRSANFQNGDYVIREGEQGDIFYMIEDGDLI 293 Query: 305 VFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 LV G + V+ V Y+ FGELAL+ ++PR A++ AQT Sbjct: 294 ATKTLVQGQEPVK--VFQYKTGDYFGELALLKDIPRQANIVAQT 335 >UniRef50_Q3SED2 Cluster: CAMP-dependent protein kinase, regulatory subunit 3-1; n=5; Paramecium tetraurelia|Rep: CAMP-dependent protein kinase, regulatory subunit 3-1 - Paramecium tetraurelia Length = 369 Score = 91.9 bits (218), Expect = 8e-18 Identities = 51/130 (39%), Positives = 79/130 (60%), Gaps = 2/130 (1%) Frame = +2 Query: 47 RKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMF 226 R +V AE Y + + ++ P KS+ Q R+ + + +F++LD + + VL AM Sbjct: 84 RAAVSAEVYG-DYNKKEDFKPRFIQKSEGQIERIKKRILNSFMFQALDEKDLNIVLGAMD 142 Query: 227 EKRSEPGEYVIRQGDDGDNFYVIENGVFDVL--VTGDDRVEKVVHTYEGSGSFGELALMY 400 EK+ + G+ VI+QGDDG+ YVI+ G + TG + EK++ TY SFGELAL+Y Sbjct: 143 EKKFQVGDEVIKQGDDGNELYVIDEGRLECYKKFTGFEE-EKLLKTYIPGESFGELALLY 201 Query: 401 NMPRAASVRA 430 N PRAA+++A Sbjct: 202 NAPRAATIKA 211 Score = 63.7 bits (148), Expect = 2e-09 Identities = 36/101 (35%), Positives = 58/101 (57%) Frame = +2 Query: 134 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 313 +R ++ E + I L +S+D + Q+ D + E++ GE +I +G+ GD Y+I G + Sbjct: 236 KREQMEEILNKIDLLQSMDNYERVQLCDVLKEEKHHAGEAIINEGEIGDRIYLIIEGELE 295 Query: 314 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 G + EK V+ Y+ FGELAL+ N PR A+V A+T Sbjct: 296 AYWKG--QTEK-VYDYKSGDYFGELALLKNTPRQATVIAKT 333 >UniRef50_A0CJF2 Cluster: Chromosome undetermined scaffold_2, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_2, whole genome shotgun sequence - Paramecium tetraurelia Length = 585 Score = 91.1 bits (216), Expect = 1e-17 Identities = 42/113 (37%), Positives = 70/113 (61%) Frame = +2 Query: 113 VFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYV 292 V PK+ Q++R+ + + LF+ L+ QQ + V +AM EK+ + E +I+QGDDGD ++ Sbjct: 317 VIPKNKDQKSRVQKKINTCYLFKHLNDQQKEIVANAMEEKKYKATETIIKQGDDGDQLFL 376 Query: 293 IENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 ++ G+ D G +K++ +Y+ FGE+AL+YN RAA++ A T LW Sbjct: 377 VDQGLLDCQKRGKQIEDKIIKSYQPGDFFGEMALLYNEKRAATIIAFTECVLW 429 Score = 52.0 bits (119), Expect = 7e-06 Identities = 30/96 (31%), Positives = 49/96 (51%), Gaps = 2/96 (2%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTG--DDRVEK 346 + + +D QQ+ DA++ + E V +Q D GD FY+I+ G L G D+ E+ Sbjct: 460 ILQQIDPYLRQQIADALYVVSFKADEVVFKQKDKGDYFYLIQEGQLKALKKGDEDEDEEQ 519 Query: 347 VVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWG 454 V + FGELA++ + R A++ +T L G Sbjct: 520 CVFEFGEFDYFGELAMLKEINRQATIVCETDCILLG 555 >UniRef50_P49605 Cluster: cAMP-dependent protein kinase regulatory subunit; n=1; Ustilago maydis|Rep: cAMP-dependent protein kinase regulatory subunit - Ustilago maydis (Smut fungus) Length = 525 Score = 89.8 bits (213), Expect = 3e-17 Identities = 65/161 (40%), Positives = 87/161 (54%), Gaps = 17/161 (10%) Frame = +2 Query: 20 PPVARFN-NRRKSVFAETYDPEEDDSD-EGAP---AVFPKSDAQRARLAEAVRGILLFRS 184 PP FN RR SV AE+ P +++ +G+P V PKS+ Q R+ ++ LLFR+ Sbjct: 160 PPT--FNLGRRTSVSAESMAPSAANAESDGSPLPKTVIPKSEEQMQRIRGSIGNNLLFRN 217 Query: 185 LDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRV-------- 340 L+ Q + VL AM E + + VI QG GD FYV+E G DV V D V Sbjct: 218 LEQDQYRDVLLAMKEVKVDANVTVIEQGAQGDYFYVVEFGTLDVYVRSPDAVSEGAPSAS 277 Query: 341 ----EKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 +K V +Y SFGELAL+Y PRAA+V + +A LW Sbjct: 278 ALLGDKKV-SYGPGSSFGELALLYAQPRAATVLSTSACTLW 317 Score = 56.4 bits (130), Expect = 3e-07 Identities = 36/102 (35%), Positives = 53/102 (51%) Frame = +2 Query: 134 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 313 +RA + + + LF L A + ++ D++ + GE VI QG+ G F++I G + Sbjct: 335 RRALYEKFLMDVPLFERLSAAERAKISDSLELREYSRGEAVISQGERGSEFFIIVEGDAE 394 Query: 314 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTA 439 V T E+VV FGELAL+ N PRAA+V A A Sbjct: 395 VRKTKQGG-EEVVGKLSRGDYFGELALLNNAPRAATVAAAGA 435 >UniRef50_Q8TF77 Cluster: cAMP-dependent protein kinase regulatory subunit; n=4; Mucoraceae|Rep: cAMP-dependent protein kinase regulatory subunit - Rhizomucor racemosus (Mucor circinelloides f. lusitanicus) Length = 427 Score = 89.8 bits (213), Expect = 3e-17 Identities = 48/111 (43%), Positives = 64/111 (57%) Frame = +2 Query: 119 PKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIE 298 P+ R+ ++ LFR+LD +Q V++AM EKR G VI QG GD FYV+E Sbjct: 167 PQISGTSERIKVSISNNFLFRNLDEEQYLDVVNAMSEKRVVKGTTVIEQGSVGDFFYVVE 226 Query: 299 NGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 +G D + G ++V YE GSFGELALMYN PRAA++ + LW Sbjct: 227 SGTLDCFI-GQNKVT----NYEAGGSFGELALMYNAPRAATIITTSDSVLW 272 Score = 72.5 bits (170), Expect = 5e-12 Identities = 37/114 (32%), Positives = 68/114 (59%) Frame = +2 Query: 89 DSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQG 268 D + AP++ + +R + ++L +SL++ + ++ DA+ E G+ V++QG Sbjct: 275 DRNTSAPSLMENTSRKRRMYEYFLSEVVLLKSLESYEQHKIADALESVYFEDGQEVVKQG 334 Query: 269 DDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 430 D GD FY+IE+G +++ ++ V++ V+ E FGELAL+ + PRAA+V A Sbjct: 335 DVGDQFYIIESGE-AIVLKEENGVQQQVNQLERGSYFGELALLNDAPRAATVVA 387 >UniRef50_UPI0001509E09 Cluster: cyclic nucleotide-binding domain containing protein; n=2; Tetrahymena thermophila SB210|Rep: cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 331 Score = 87.8 bits (208), Expect = 1e-16 Identities = 48/137 (35%), Positives = 79/137 (57%), Gaps = 1/137 (0%) Frame = +2 Query: 44 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 223 +R SV AE Y + + P V KS + ++ + + +F LD ++ + +++AM Sbjct: 47 QRNSVSAEAYGMF-NKRENFKPIVIAKSQDTKNKIYKRINEAFMFNCLDLKEREIIVNAM 105 Query: 224 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKV-VHTYEGSGSFGELALMY 400 EKR + G+ VI+QG++G+ YVI+ G D ++ E + TY+ SFGELAL+Y Sbjct: 106 EEKRFKSGDQVIKQGEEGNYLYVIDEGQLDCFKKYQNQPEPTYLKTYQPGESFGELALLY 165 Query: 401 NMPRAASVRAQTAGALW 451 N PRAAS+ ++T L+ Sbjct: 166 NAPRAASIVSKTPSVLF 182 >UniRef50_P05987 Cluster: cAMP-dependent protein kinase regulatory subunit; n=2; Dictyostelium discoideum|Rep: cAMP-dependent protein kinase regulatory subunit - Dictyostelium discoideum (Slime mold) Length = 327 Score = 87.0 bits (206), Expect = 2e-16 Identities = 53/139 (38%), Positives = 79/139 (56%), Gaps = 1/139 (0%) Frame = +2 Query: 38 NNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLD 217 N RK A + +P D P + PK+ + RL +A+ ++F L+ ++ V Sbjct: 22 NITRKRRGAISSEPLGDKPATPLPNI-PKTVETQQRLEQALSNNIMFSHLEEEERNVVFL 80 Query: 218 AMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV-TGDDRVEKVVHTYEGSGSFGELAL 394 AM E + G+ +I+QGD+GD FYVI++G+ D+ V V+ +EG GSFGELAL Sbjct: 81 AMVEVLYKAGDIIIKQGDEGDLFYVIDSGICDIYVCQNGGSPTLVMEVFEG-GSFGELAL 139 Query: 395 MYNMPRAASVRAQTAGALW 451 +Y PRAA+V A+T LW Sbjct: 140 IYGSPRAATVIARTDVRLW 158 Score = 62.5 bits (145), Expect = 5e-09 Identities = 35/100 (35%), Positives = 51/100 (51%), Gaps = 3/100 (3%) Frame = +2 Query: 134 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG--- 304 +R E + + + R +D + + DA+ + GE ++RQGD GD FY+I G Sbjct: 176 KRKLYEEFLEKVSILRHIDKYERVSLADALEPVNFQDGEVIVRQGDPGDRFYIIVEGKVV 235 Query: 305 VFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASV 424 V V GD VV S FGE+AL+ + PRAA+V Sbjct: 236 VTQETVPGDHSTSHVVSELHPSDYFGEIALLTDRPRAATV 275 >UniRef50_A0BNE3 Cluster: Chromosome undetermined scaffold_118, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_118, whole genome shotgun sequence - Paramecium tetraurelia Length = 374 Score = 86.6 bits (205), Expect = 3e-16 Identities = 50/131 (38%), Positives = 74/131 (56%), Gaps = 2/131 (1%) Frame = +2 Query: 47 RKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMF 226 R SV AE Y ++ P + KS Q ++ E + +F LD ++ V++AM Sbjct: 87 RASVSAEVYGIYNKKTNF-KPKIVAKSHLQIQKIKEKLAQSFMFSELDEHDLRIVINAME 145 Query: 227 EKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT--GDDRVEKVVHTYEGSGSFGELALMY 400 + + G+ +IRQGDDGDN Y+++ G D T G D V + TY+ SFGELAL+Y Sbjct: 146 VIQCKKGDIIIRQGDDGDNLYIVDEGTLDCSRTKAGQDSVH--LKTYKPGESFGELALLY 203 Query: 401 NMPRAASVRAQ 433 N PRAA++ A+ Sbjct: 204 NSPRAATIVAE 214 Score = 65.7 bits (153), Expect = 6e-10 Identities = 34/102 (33%), Positives = 55/102 (53%), Gaps = 1/102 (0%) Frame = +2 Query: 134 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG-VF 310 +R R + + L + LD Q+ DA+ + G+Y++++GD+GD FY +E G Sbjct: 238 KRERYEYFLAHVELLQELDPYSRSQIADALKSRNFNIGDYIVKEGDEGDIFYFLEKGEAV 297 Query: 311 DVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 V + + V+ Y+ FGE+AL+ PRAASV A+T Sbjct: 298 ATKVLNQSQPAQEVYFYKEGDYFGEIALLRQAPRAASVIAET 339 >UniRef50_Q6C2X0 Cluster: cAMP-dependent protein kinase regulatory subunit; n=1; Yarrowia lipolytica|Rep: cAMP-dependent protein kinase regulatory subunit - Yarrowia lipolytica (Candida lipolytica) Length = 375 Score = 86.6 bits (205), Expect = 3e-16 Identities = 58/143 (40%), Positives = 77/143 (53%) Frame = +2 Query: 23 PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQM 202 P A F RR SV AE+ P A S Q L ++V LF +LD + Sbjct: 94 PAAPFT-RRTSVSAESIAPGAFAGAASGVASNNLSAEQLESLYKSVSHNFLFGNLDEEAC 152 Query: 203 QQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFG 382 + VL ++ EK+ + GE +I QGD+GD FY++E+G + + G KV + GS SFG Sbjct: 153 RSVLQSLQEKKCDSGEKIITQGDEGDYFYIVESGAVEFIKDG----VKVNSSGPGS-SFG 207 Query: 383 ELALMYNMPRAASVRAQTAGALW 451 ELALMYN PRAA+V A LW Sbjct: 208 ELALMYNAPRAATVVATQPCVLW 230 Score = 58.4 bits (135), Expect = 9e-08 Identities = 31/93 (33%), Positives = 55/93 (59%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 337 ++ + + L + + ++ DA+ + EPG VI +G+ GD FY++E+G +V G+ Sbjct: 256 LKEVPILSDLGSYERNKLADALTSQVVEPGTAVITEGEAGDAFYLVESGEAEVTKKGE-- 313 Query: 338 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 VV T + FGE+AL+ ++PR A+V A+T Sbjct: 314 -SGVVATLKQGDYFGEVALLNDLPRQATVTAKT 345 >UniRef50_Q9XTM6 Cluster: CAMP-dependent protein kinase regulatory subunit; n=1; Euplotes octocarinatus|Rep: CAMP-dependent protein kinase regulatory subunit - Euplotes octocarinatus Length = 338 Score = 86.2 bits (204), Expect = 4e-16 Identities = 44/114 (38%), Positives = 66/114 (57%), Gaps = 1/114 (0%) Frame = +2 Query: 113 VFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYV 292 V PKSD + ++ + LF SLD + ++ V++AM K EP VI+QGDDG ++ Sbjct: 70 VVPKSDELKTQIRTRLLQSFLFSSLDDRDLEIVINAMEVKTFEPSSTVIKQGDDGAELFL 129 Query: 293 IENGVFDVL-VTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 + G D V K++ YE +FGELAL+YN PRAA+++A+T L+ Sbjct: 130 VGEGTLDCFKVMKKGEEAKLIKEYEPGDAFGELALLYNAPRAATIKAKTEAVLY 183 Score = 71.3 bits (167), Expect = 1e-11 Identities = 37/104 (35%), Positives = 61/104 (58%), Gaps = 3/104 (2%) Frame = +2 Query: 134 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG--- 304 +R + + ++ + + S+ + Q+ DA+ E++ PG+YVI+QG+ GD FY+I G Sbjct: 201 KREKYEKCLKNVKVLDSVSIYERSQIADAIKEQKFNPGDYVIKQGEIGDTFYMISEGEAT 260 Query: 305 VFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 + + G E + +TY FGE+AL+ N PRAASV A+T Sbjct: 261 AYKIFEEGGKEEEVMKYTY--GDYFGEIALLKNEPRAASVVAKT 302 >UniRef50_A0BRC9 Cluster: Chromosome undetermined scaffold_122, whole genome shotgun sequence; n=4; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_122, whole genome shotgun sequence - Paramecium tetraurelia Length = 374 Score = 86.2 bits (204), Expect = 4e-16 Identities = 47/145 (32%), Positives = 78/145 (53%), Gaps = 2/145 (1%) Frame = +2 Query: 23 PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQM 202 PV R SV AE + + + P V PK++ Q+ ++ E + + +F++L + Sbjct: 78 PVKNAKTFRSSVSAEVFGVH-NKKENFIPRVIPKTEEQKQQILEKLMKVFMFQALGQHEQ 136 Query: 203 QQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL--VTGDDRVEKVVHTYEGSGS 376 + V++AM EK ++VI QGDDG Y++ +G D + D K + Y+ Sbjct: 137 EIVVNAMEEKHYTKDDWVITQGDDGAELYIVFSGELDCFRKMKPTDPEPKFLKKYKPGDM 196 Query: 377 FGELALMYNMPRAASVRAQTAGALW 451 FGEL+L+YN PRAAS++A+ L+ Sbjct: 197 FGELSLLYNSPRAASIQAKEDSVLF 221 Score = 66.1 bits (154), Expect = 4e-10 Identities = 30/101 (29%), Positives = 60/101 (59%) Frame = +2 Query: 134 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 313 +R + E + + L +S++A + Q+ D + E+ + GE +I++G++GD FY++ G Sbjct: 239 KRLQYEEVLSKVELLQSMEAYEKTQICDGLKEQTYQKGEVIIQEGEEGDKFYMVAEGTLA 298 Query: 314 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 + + +V+ Y+ FGELAL++ +PR A++ A+T Sbjct: 299 AYKDNNGQQVEVLR-YQPGDYFGELALIHKLPRQATIIAET 338 >UniRef50_Q4UEK0 Cluster: CAMP-dependent protein kinase regulatory subunit, putative; n=2; Theileria|Rep: CAMP-dependent protein kinase regulatory subunit, putative - Theileria annulata Length = 313 Score = 85.8 bits (203), Expect = 5e-16 Identities = 47/135 (34%), Positives = 73/135 (54%) Frame = +2 Query: 47 RKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMF 226 R SV AE + S P + K+ ++A++ E ++ LF +++ + ++ A Sbjct: 21 RLSVSAEVFGDNHSKSKVVIPN-YEKTPQEQAKIMEMIKRCFLFSGVNSSGLDLLVKAFD 79 Query: 227 EKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNM 406 K + PG+ +I+QGDDGD Y+IE+G +V E+ + FGELALMYN Sbjct: 80 FKTANPGDVLIKQGDDGDKLYLIESGTVEVTRKNATGQEEFLCNLTAGDYFGELALMYNS 139 Query: 407 PRAASVRAQTAGALW 451 PRAA+V A+T LW Sbjct: 140 PRAATVVAKTEMHLW 154 Score = 43.6 bits (98), Expect = 0.003 Identities = 25/87 (28%), Positives = 47/87 (54%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 352 LF+ ++ ++ DA+ E+ E E VI+QG+ G + +++ G + V K+V Sbjct: 185 LFKKVNPYDRCRLADALVERTFED-ETVIKQGEPGSSLFMVLEGQAESFVEN-----KLV 238 Query: 353 HTYEGSGSFGELALMYNMPRAASVRAQ 433 +Y FGE+ + PRA++V+A+ Sbjct: 239 KSYNPGDYFGEIGFILKKPRASTVKAK 265 >UniRef50_Q33DX2 Cluster: Putative cyclic AMP-dependent protein kinase regulatory subunit; n=1; Schizophyllum commune|Rep: Putative cyclic AMP-dependent protein kinase regulatory subunit - Schizophyllum commune (Bracket fungus) Length = 500 Score = 69.3 bits (162), Expect(2) = 1e-15 Identities = 37/102 (36%), Positives = 54/102 (52%) Frame = +2 Query: 17 KPPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQ 196 +PP A RR SV AE+ + + +E VFPK+ Q R+ + +FR L + Sbjct: 163 QPPNASIFARRASVSAESISVDALNREETKTRVFPKTPDQMRRIQSSTANNFIFRDLTEE 222 Query: 197 QMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV 322 Q + V AM E + VIRQGDDGD FY++E+G+ + Sbjct: 223 QKRAVFLAMQEMTVDKDTVVIRQGDDGDYFYIVESGLLHCFI 264 Score = 60.9 bits (141), Expect = 2e-08 Identities = 35/102 (34%), Positives = 56/102 (54%), Gaps = 3/102 (2%) Frame = +2 Query: 134 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 313 +R+ + + + L SLDA + ++ DA+ + E G+ V++QG+ GD F+ +E G Sbjct: 357 RRSMYEQFLSTVTLLSSLDASERSKIADALVSRVYEDGQAVVKQGETGDTFFFVEEGEAC 416 Query: 314 VL---VTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 430 V G+D E VV + FGEL+L+ PRAA+V A Sbjct: 417 VTKRPQDGEDGEEIVVGHLKKGDYFGELSLLRLAPRAATVSA 458 Score = 35.5 bits (78), Expect(2) = 1e-15 Identities = 18/36 (50%), Positives = 21/36 (58%) Frame = +2 Query: 344 KVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 K V Y SFGELALMY RAA+V + +LW Sbjct: 304 KRVAEYPAGTSFGELALMYGHARAATVLSVEPSSLW 339 >UniRef50_A2R984 Cluster: Catalytic activity: ATP + a protein <=> ADP + a phosphoprotein; n=1; Aspergillus niger|Rep: Catalytic activity: ATP + a protein <=> ADP + a phosphoprotein - Aspergillus niger Length = 417 Score = 83.8 bits (198), Expect = 2e-15 Identities = 53/135 (39%), Positives = 73/135 (54%), Gaps = 8/135 (5%) Frame = +2 Query: 44 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 223 RR SV AE++ P + + F ++ Q RL AV+ + LF +LD +Q Q+L A Sbjct: 79 RRNSVSAESFVPGQQSLPSTS---FDMTEEQAHRLVRAVKEVFLFSALDKEQYAQLLSAF 135 Query: 224 FEKRSE-PGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKV---VHTYEGSGS----F 379 K G VI QGD GDNFY++E G FD+ +T + + T GS F Sbjct: 136 VGKAVPIKGTNVITQGDIGDNFYIVEKGSFDIYITLASTPQPTTPSIGTKHGSAHPGDFF 195 Query: 380 GELALMYNMPRAASV 424 GELAL+YN PRAA++ Sbjct: 196 GELALLYNAPRAATI 210 Score = 49.6 bits (113), Expect = 4e-05 Identities = 34/93 (36%), Positives = 48/93 (51%), Gaps = 5/93 (5%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKV- 349 L L +Q ++ +A+ +R G+ +I QGD G +F++ LV+G+ R KV Sbjct: 251 LLAGLSGRQRSRIAEALQTRRYCAGDTIILQGDLGSDFFL--------LVSGEARAYKVG 302 Query: 350 ----VHTYEGSGSFGELALMYNMPRAASVRAQT 436 V TY G FGE A N PRAAS+ A T Sbjct: 303 FVGSVKTYTSGGWFGERAFRKNAPRAASIMAIT 335 >UniRef50_A3FPL6 Cluster: CAMP-dependent protein kinase regulatory subunit; n=2; Cryptosporidium|Rep: CAMP-dependent protein kinase regulatory subunit - Cryptosporidium parvum Iowa II Length = 345 Score = 83.4 bits (197), Expect = 3e-15 Identities = 49/135 (36%), Positives = 69/135 (51%) Frame = +2 Query: 47 RKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMF 226 R SV AE Y D P+ +PK+ Q R+ E + +F SLD +++ V+ A Sbjct: 58 RTSVSAEAYGAWNKMKDFTPPS-YPKTKEQEKRIREKLLESFMFTSLDDDELKTVILACV 116 Query: 227 EKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNM 406 E + +I QGD+GD Y+I+ GV + K + +FGELAL+YN Sbjct: 117 ETSVKKDTEIITQGDNGDKLYIIDQGVVECYKKTSTEPRKHLCDLNPGDAFGELALLYNC 176 Query: 407 PRAASVRAQTAGALW 451 PRAASV A+T LW Sbjct: 177 PRAASVVAKTDCLLW 191 Score = 55.6 bits (128), Expect = 6e-07 Identities = 31/92 (33%), Positives = 54/92 (58%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 337 ++ + + +++D ++ ++ + E G+ +I+QG+ GD FY+I G V D Sbjct: 217 LKEVEILKTMDVYELNKLTMVLKSSIFEDGQEIIKQGEQGDTFYLIITG---NAVALKDN 273 Query: 338 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQ 433 VE V +Y+ FGELAL+ N PRAA+V+A+ Sbjct: 274 VE--VMSYKRGDYFGELALLRNAPRAATVKAR 303 >UniRef50_A7AU83 Cluster: cAMP-dependent protein kinase regulatory subunit , putative; n=1; Babesia bovis|Rep: cAMP-dependent protein kinase regulatory subunit , putative - Babesia bovis Length = 317 Score = 81.0 bits (191), Expect = 1e-14 Identities = 56/143 (39%), Positives = 73/143 (51%), Gaps = 2/143 (1%) Frame = +2 Query: 29 ARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQ 208 AR NR S+ AE + + AP V K+ Q R+ E V LF S+DA+ + Sbjct: 17 ARARNR-VSISAEVFGAYNNPDLFVAP-VHEKTPEQATRIKETVLKCFLFSSVDAKDIDT 74 Query: 209 VLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGV--FDVLVTGDDRVEKVVHTYEGSGSFG 382 ++ A G VI+QGD GD Y+IE+G F ++V + EG G FG Sbjct: 75 LVKAFESSDVSAGTKVIQQGDPGDKLYLIESGTARFTKTSAATEQVHDLGTAGEG-GCFG 133 Query: 383 ELALMYNMPRAASVRAQTAGALW 451 ELALMYN PRA SV A+T LW Sbjct: 134 ELALMYNAPRACSVVAETDMKLW 156 Score = 48.0 bits (109), Expect = 1e-04 Identities = 30/100 (30%), Positives = 54/100 (54%) Frame = +2 Query: 134 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 313 +R + ++ + L +LD ++ DA+ EK + E +I +GD G + ++I G + Sbjct: 174 KREKYDSLLQSVALLSNLDPYDRCRLADALTEK-TFVDEDIIVEGDKGTSVFMILEGNAE 232 Query: 314 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQ 433 G K+V +Y G FGE+AL+ PRA++V+A+ Sbjct: 233 AYCQG-----KLVKSYSEGGYFGEIALIAQTPRASTVKAK 267 >UniRef50_P36600 Cluster: cAMP-dependent protein kinase regulatory subunit; n=1; Schizosaccharomyces pombe|Rep: cAMP-dependent protein kinase regulatory subunit - Schizosaccharomyces pombe (Fission yeast) Length = 412 Score = 80.6 bits (190), Expect = 2e-14 Identities = 57/143 (39%), Positives = 77/143 (53%), Gaps = 12/143 (8%) Frame = +2 Query: 44 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRA-RLAEAVRGILLFRSLDAQQMQQVLDA 220 RR+SV E+ +P + FP D + RL +V G LF++LD + +VL+A Sbjct: 101 RRQSVSTESMNPSAFALE--TKRTFPPKDPEDLKRLKRSVAGNFLFKNLDEEHYNEVLNA 158 Query: 221 MFEKR-SEPGEYVIRQGDDGDNFYVIENGVFDVL------VTGDDRVE----KVVHTYEG 367 M EKR E G VI QG GD FY++E G FDV +T ++ + + T Sbjct: 159 MTEKRIGEAGVAVIVQGAVGDYFYIVEQGEFDVYKRPELNITPEEVLSSGYGNYITTISP 218 Query: 368 SGSFGELALMYNMPRAASVRAQT 436 FGELALMYN PRAASV ++T Sbjct: 219 GEYFGELALMYNAPRAASVVSKT 241 Score = 64.1 bits (149), Expect = 2e-09 Identities = 40/108 (37%), Positives = 59/108 (54%) Frame = +2 Query: 113 VFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYV 292 VF + QR + + + SLD Q Q++ DA+ + G VIRQGD G+ FY+ Sbjct: 258 VFENAYRQRMLYESLLEEVPILSSLDKYQRQKIADALQTVVYQAGSIVIRQGDIGNQFYL 317 Query: 293 IENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 IE+G +V+ G + VV T FGELAL++ R A+V+A+T Sbjct: 318 IEDGEAEVVKNG----KGVVVTLTKGDYFGELALIHETVRNATVQAKT 361 >UniRef50_A0CMC2 Cluster: Chromosome undetermined scaffold_21, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_21, whole genome shotgun sequence - Paramecium tetraurelia Length = 334 Score = 77.8 bits (183), Expect = 1e-13 Identities = 49/138 (35%), Positives = 79/138 (57%), Gaps = 2/138 (1%) Frame = +2 Query: 44 RRKSVFAETYDPEEDDSDEGAPAVF-PKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDA 220 +R SV AE Y + + E A F PKS Q R+ + ++ +F +L+ ++++ V+ A Sbjct: 50 QRFSVSAEAYG--QFNKKENFKAKFIPKSKEQSERIKQRMQAGFMFSALNEKEIEIVVGA 107 Query: 221 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 400 M EK EYVI+QG++G+ YV++ G D + + ++ TY SFGELAL++ Sbjct: 108 MEEKIFHKAEYVIKQGEEGNVLYVVDTGELDCF-KNYGKGDVLLKTYYPGESFGELALLF 166 Query: 401 NMPRAASVRAQTAGA-LW 451 PRAAS+ ++ A LW Sbjct: 167 QSPRAASIIVKSDKAILW 184 Score = 32.7 bits (71), Expect = 4.9 Identities = 13/45 (28%), Positives = 25/45 (55%) Frame = +2 Query: 170 LLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG 304 LL D ++ DA+FEK+ + G+ +++QG +++E G Sbjct: 215 LLKEIKDPYDKLKMSDALFEKQYKKGDVILQQGQKSQEIFILEQG 259 >UniRef50_UPI0000D562F1 Cluster: PREDICTED: similar to CG3324-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG3324-PA - Tribolium castaneum Length = 636 Score = 73.7 bits (173), Expect = 2e-12 Identities = 34/89 (38%), Positives = 55/89 (61%) Frame = +2 Query: 185 LDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYE 364 L +++Q V+D M+ + P + +I++GDDG + YV G ++V+ G KVV T+ Sbjct: 70 LQNKKLQDVVDCMYPESVSPSQTIIKEGDDGSHLYVSVTGTYEVIQNG-----KVVKTFS 124 Query: 365 GSGSFGELALMYNMPRAASVRAQTAGALW 451 FGELAL+YN R A+++A+T G +W Sbjct: 125 DVRVFGELALLYNAKRIATIKARTFGKVW 153 Score = 40.3 bits (90), Expect = 0.024 Identities = 27/104 (25%), Positives = 52/104 (50%), Gaps = 1/104 (0%) Frame = +2 Query: 134 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGD-DGDNFYVIENGVF 310 QR + + ++ + S+ + +++V + G ++ +G+ + D FY+I+ G Sbjct: 171 QRQEIVDFLKQVPKLNSVPLEVLEEVASLLKLDFFPTGTKIVEEGEVNPDKFYIIKAGSV 230 Query: 311 DVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAG 442 V + ++K+ Y+GS FGELAL+ R A+V A G Sbjct: 231 TVSKKNEGAIDKL---YKGS-FFGELALLKEKERKATVMADPPG 270 >UniRef50_Q3SEP0 Cluster: CGMP-dependent protein kinase 8-2; n=8; Paramecium tetraurelia|Rep: CGMP-dependent protein kinase 8-2 - Paramecium tetraurelia Length = 795 Score = 70.9 bits (166), Expect = 2e-11 Identities = 40/116 (34%), Positives = 65/116 (56%) Frame = +2 Query: 107 PAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNF 286 P + P++ + + + +F S++ Q+ Q+ +MF R G+ +I+QGD +F Sbjct: 76 PLMKPQTPQDIGFIVKCFQSHFVFSSMNETQLVQLAKSMFYCRLVIGQTIIKQGDGASSF 135 Query: 287 YVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWG 454 +V+E G +VLV G R + +G+G FGELAL+YN PR+A+ A LWG Sbjct: 136 FVLEKGKINVLVDGISRKQLT----QGNG-FGELALLYNAPRSATCVAMEECFLWG 186 Score = 35.5 bits (78), Expect = 0.70 Identities = 21/101 (20%), Positives = 45/101 (44%), Gaps = 1/101 (0%) Frame = +2 Query: 131 AQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVF 310 +++ + + + + F L Q + + ++ E ++ +GD +FY+I G Sbjct: 202 SEQEKNRQLLEQVKFFNQLTKDQKDAIAGVLILQKFNQNEIIVNEGDQASSFYIIVEGKC 261 Query: 311 DVLVTGDDRVEKVVHTYEGSGSFGELALMY-NMPRAASVRA 430 V ++ + + T SFGE AL + N R +++A Sbjct: 262 GVF----NKEDVQIATLNPKDSFGESALKHDNQIRMMTIKA 298 >UniRef50_Q8MQE4 Cluster: Putative uncharacterized protein; n=5; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 617 Score = 69.3 bits (162), Expect = 5e-11 Identities = 43/113 (38%), Positives = 61/113 (53%) Frame = +2 Query: 113 VFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYV 292 + KSDA + A+R R+LDA Q++++ AM+ G +IRQGD G YV Sbjct: 52 IIGKSDAAFETIGNALRLNSFLRNLDATQIEKISSAMYPVEVPAGAIIIRQGDLGSIMYV 111 Query: 293 IENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 I+ G V V D+R V T E FGELA++++ R A+VRA + LW Sbjct: 112 IQEG--KVQVVKDNR---FVRTMEDGALFGELAILHHCERTATVRAIESCHLW 159 >UniRef50_UPI000065ED67 Cluster: cAMP-dependent protein kinase type I-beta regulatory subunit.; n=1; Takifugu rubripes|Rep: cAMP-dependent protein kinase type I-beta regulatory subunit. - Takifugu rubripes Length = 403 Score = 68.9 bits (161), Expect = 6e-11 Identities = 37/63 (58%), Positives = 44/63 (69%) Frame = +2 Query: 266 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGA 445 GD+GDNFYVI+ G DV V G E V + EG GSFGELAL+Y PRAA+V+A+T Sbjct: 190 GDEGDNFYVIDQGEVDVYVNG----ELVTNIGEG-GSFGELALIYGTPRAATVKAKTDLK 244 Query: 446 LWG 454 LWG Sbjct: 245 LWG 247 Score = 59.3 bits (137), Expect = 5e-08 Identities = 36/101 (35%), Positives = 54/101 (53%), Gaps = 1/101 (0%) Frame = +2 Query: 134 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 313 +R E + + + SLD + V DA+ + E GE ++ QG G++F++I G+ Sbjct: 264 KRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGEKIVVQGAPGNDFFIITEGIAS 323 Query: 314 VLVTGDDRVEKV-VHTYEGSGSFGELALMYNMPRAASVRAQ 433 VL D E V V S FGE+AL+ N PRAA+V A+ Sbjct: 324 VLQRRSDNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVAR 364 >UniRef50_Q03042 Cluster: cGMP-dependent protein kinase, isozyme 1; n=28; Eumetazoa|Rep: cGMP-dependent protein kinase, isozyme 1 - Drosophila melanogaster (Fruit fly) Length = 768 Score = 68.5 bits (160), Expect = 8e-11 Identities = 36/113 (31%), Positives = 64/113 (56%), Gaps = 1/113 (0%) Frame = +2 Query: 116 FPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVI 295 + K + + ++ +A+ +++DA Q+++++D+M+ K GE+VIR+G+ G + YV Sbjct: 166 YEKDFSDKQQIKDAIMDNDFLKNIDASQVRELVDSMYSKSIAAGEFVIREGEVGAHLYVS 225 Query: 296 ENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA-QTAGALW 451 G F V+ G KV+ +FGELA++YN R AS+R A +W Sbjct: 226 AAGEFAVMQQG-----KVLDKMGAGKAFGELAILYNCTRTASIRVLSEAARVW 273 Score = 44.0 bits (99), Expect = 0.002 Identities = 28/97 (28%), Positives = 47/97 (48%), Gaps = 2/97 (2%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL--VTGD 331 +R + L +L + + ++ D + + G Y+IRQG GD+F++I G V +T Sbjct: 299 LRSVPLLMNLSEELLAKIADVLELEFYAAGTYIIRQGTAGDSFFLISQGNVRVTQKLTPT 358 Query: 332 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAG 442 E + T FGE AL+ R A++ A + G Sbjct: 359 SPEETELRTLSRGDYFGEQALINEDKRTANIIALSPG 395 >UniRef50_Q13237 Cluster: cGMP-dependent protein kinase 2; n=23; Euteleostomi|Rep: cGMP-dependent protein kinase 2 - Homo sapiens (Human) Length = 762 Score = 66.9 bits (156), Expect = 2e-10 Identities = 36/128 (28%), Positives = 68/128 (53%) Frame = +2 Query: 68 TYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPG 247 TYD + A K +++ + +A+ + LD QQ++ +++ M+ + + G Sbjct: 133 TYDLNKPPEFSFEKARVRKDSSEKKLITDALNKNQFLKRLDPQQIKDMVECMYGRNYQQG 192 Query: 248 EYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVR 427 Y+I+QG+ G++ +V+ G +V + EK++ + +FGELA++YN R ASV+ Sbjct: 193 SYIIKQGEPGNHIFVLAEGRLEVF-----QGEKLLSSIPMWTTFGELAILYNCTRTASVK 247 Query: 428 AQTAGALW 451 A T W Sbjct: 248 AITNVKTW 255 Score = 49.6 bits (113), Expect = 4e-05 Identities = 24/94 (25%), Positives = 55/94 (58%), Gaps = 2/94 (2%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL--VTGD 331 +R + L ++L ++ +++D + + + G+Y+IR+G++G F+++ G V G Sbjct: 281 LRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGH 340 Query: 332 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQ 433 D+ +++ T + FGE AL+ + R+A++ A+ Sbjct: 341 DQ-PQLIKTLQKGEYFGEKALISDDVRSANIIAE 373 >UniRef50_A7C1J1 Cluster: Protein kinase, cGMP-dependent, type I; n=1; Beggiatoa sp. PS|Rep: Protein kinase, cGMP-dependent, type I - Beggiatoa sp. PS Length = 429 Score = 66.5 bits (155), Expect = 3e-10 Identities = 34/93 (36%), Positives = 56/93 (60%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 352 LF + QQ+++++ ++ K+ +P E +IRQGDD Y+IE G+F V + D+R +VV Sbjct: 144 LFTYVPTQQLRRLVSSLKAKKLQPNEILIRQGDDAKEAYIIEKGLFTVQI--DERPNQVV 201 Query: 353 HTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 T GE+AL+ N R +V AQT +++ Sbjct: 202 RTMIPGDLVGEIALVKNTKRTTNVIAQTRASVF 234 >UniRef50_Q5CWD4 Cluster: Cyclic nucleotide (CGMP)-dependent protein kinase with 3 cNMP binding domains and a Ser/Thr kinase domain; n=3; Cryptosporidium|Rep: Cyclic nucleotide (CGMP)-dependent protein kinase with 3 cNMP binding domains and a Ser/Thr kinase domain - Cryptosporidium parvum Iowa II Length = 965 Score = 66.5 bits (155), Expect = 3e-10 Identities = 38/113 (33%), Positives = 62/113 (54%) Frame = +2 Query: 122 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 301 K++ +++A+ G ++ SL+ ++ ++ +M E GE VI QG G F+VI Sbjct: 92 KTEEDIKTISKALAGNVVGASLNESEIATLVSSMHYYEYEVGEVVIEQGASGFYFFVIST 151 Query: 302 GVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWGHG 460 G F V + G+ V+T +FGELAL++N PR+A++ G LWG G Sbjct: 152 GSFGVEINGNR-----VNTMSEGTAFGELALIHNTPRSATILVIEKGGLWGLG 199 Score = 46.8 bits (106), Expect = 3e-04 Identities = 28/104 (26%), Positives = 54/104 (51%), Gaps = 1/104 (0%) Frame = +2 Query: 143 RLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV 322 R +A++ +F+ + QQ+ ++ ++ + GE ++ QGD G F+++++G V Sbjct: 489 RKRDAIKSCFVFQYVSEQQLSLLVKSLRLVKFTSGEKIVVQGDKGTAFFILQSGEVAVY- 547 Query: 323 TGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGA-LW 451 R K + + FGE AL+Y+ R+A++ A T LW Sbjct: 548 ----RNNKFIRYLGKNDYFGERALLYDELRSATIEAATPEVHLW 587 Score = 41.9 bits (94), Expect = 0.008 Identities = 23/91 (25%), Positives = 49/91 (53%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 337 + + +F L +Q + +A+ + + +IR+ + G+ Y+I++G+ V V Sbjct: 222 IESLSIFSGLTDKQKSLLSEALVREIFVKDQVIIREKEIGNVLYMIKSGIVGVFVE---- 277 Query: 338 VEKVVHTYEGSGSFGELALMYNMPRAASVRA 430 +K + + +FGE +LM++ PR+A+V A Sbjct: 278 -DKYIRSLNEGDAFGERSLMFDEPRSATVIA 307 >UniRef50_A0E3G7 Cluster: Chromosome undetermined scaffold_76, whole genome shotgun sequence; n=5; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_76, whole genome shotgun sequence - Paramecium tetraurelia Length = 864 Score = 65.7 bits (153), Expect = 6e-10 Identities = 31/93 (33%), Positives = 55/93 (59%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 352 +F+S+ ++ V+D MF G++V +QGD ++++IE G +++ G+ + Sbjct: 117 IFKSVPQSDIEYVVDQMFYCTVPDGQFVFKQGDMASSYFLIERGQCQIIINGE-----LK 171 Query: 353 HTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 T + +FGELA++YN PR+ASV+A A W Sbjct: 172 KTLKSGDAFGELAMLYNAPRSASVKAIGDCAFW 204 Score = 45.6 bits (103), Expect = 7e-04 Identities = 26/93 (27%), Positives = 47/93 (50%) Frame = +2 Query: 152 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 331 E ++ + F L +Q + + + GE ++ +GD ++FY+I+ G ++ GD Sbjct: 228 EFMKKVEFFSFLTEEQRDAISSVLITSVFKKGEIIVSEGDVANSFYIIKKGKV-AIIKGD 286 Query: 332 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 430 V ++ SFGE AL + RAA+V+A Sbjct: 287 KEVSQM----NAGESFGEAALYQSCQRAATVKA 315 >UniRef50_A2EKL9 Cluster: Cyclic nucleotide-binding domain containing protein; n=2; Trichomonas vaginalis G3|Rep: Cyclic nucleotide-binding domain containing protein - Trichomonas vaginalis G3 Length = 374 Score = 65.3 bits (152), Expect = 8e-10 Identities = 38/112 (33%), Positives = 60/112 (53%), Gaps = 1/112 (0%) Frame = +2 Query: 119 PKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIE 298 PK+ + ++ + + L + Q+ +++A F+ + + +I+QGD DNFY+I+ Sbjct: 117 PKTPEEYTQIETICKKVSFLSYLKSDQLDALINAFFKMEFKDKDVIIKQGDKPDNFYIIQ 176 Query: 299 NGVFDV-LVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 +G D+ TGD KV+ EGS FGELALM RAA+V A W Sbjct: 177 SGNVDIWKKTGDAPEVKVITLSEGS-YFGELALMSGRTRAATVIAAGTVYCW 227 Score = 53.6 bits (123), Expect = 2e-06 Identities = 32/97 (32%), Positives = 50/97 (51%) Frame = +2 Query: 134 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 313 +R + E + + +F L Q V +A + +P +I+QG+ G+ FYVI G D Sbjct: 245 RRQKCKEIISEVPIFNQLPDYQAILVAEAAVLEEYQPATTIIKQGEIGNKFYVILAGTVD 304 Query: 314 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASV 424 V++ G K V+ FGE AL+YN RAA++ Sbjct: 305 VIIDG-----KKVNELGPGKYFGERALIYNCARAATI 336 >UniRef50_Q8MMZ4 Cluster: CGMP-dependent protein kinase; n=14; Apicomplexa|Rep: CGMP-dependent protein kinase - Plasmodium falciparum Length = 853 Score = 64.9 bits (151), Expect = 1e-09 Identities = 41/138 (29%), Positives = 71/138 (51%) Frame = +2 Query: 41 NRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDA 220 N++K++F+ ED E + K + +++ L+ +L+ ++ + + Sbjct: 14 NKKKAIFSNDDFTGEDSLMEDHLELREKLSEDIDMIKTSLKNNLVCSTLNDNEILTLSNY 73 Query: 221 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 400 M + G VI+QG+ G F++I +G FDV V +K V T SFGE AL++ Sbjct: 74 MQFFVFKSGNLVIKQGEKGSYFFIINSGKFDVYVN-----DKKVKTMGKGSSFGEAALIH 128 Query: 401 NMPRAASVRAQTAGALWG 454 N R+A++ A+T G LWG Sbjct: 129 NTQRSATIIAETDGTLWG 146 Score = 59.7 bits (138), Expect = 4e-08 Identities = 30/89 (33%), Positives = 54/89 (60%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 337 ++ + +FR L +Q +++A R E G+Y+I++G+ G FY+I+NG +++ + Sbjct: 413 IKKMYIFRYLTDKQCNLLIEAFRTTRYEEGDYIIQEGEVGSRFYIIKNGEVEIV-----K 467 Query: 338 VEKVVHTYEGSGSFGELALMYNMPRAASV 424 +K + T + FGE AL+Y+ PR ASV Sbjct: 468 NKKRLRTLGKNDYFGERALLYDEPRTASV 496 Score = 49.6 bits (113), Expect = 4e-05 Identities = 25/92 (27%), Positives = 48/92 (52%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 337 + + +F L Q + +A + + GE +++QGD GD Y+++ G V + ++ Sbjct: 171 IDSVSVFDMLTEAQKNMITNACVIQNFKSGETIVKQGDYGDVLYILKEGKATVYINDEE- 229 Query: 338 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQ 433 + E FGE AL+Y+ PR+A++ A+ Sbjct: 230 ----IRVLEKGSYFGERALLYDEPRSATIIAK 257 >UniRef50_Q22RR1 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 1219 Score = 64.9 bits (151), Expect = 1e-09 Identities = 34/102 (33%), Positives = 58/102 (56%) Frame = +2 Query: 137 RARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDV 316 + ++ A+R +F +L+ Q M QV++ MF + GE++ Q D+ F+ IE G ++ Sbjct: 437 KQKIKAAIRRHFIFSNLEEQHMNQVVNKMFACTCKQGEFIFEQNDEASLFFFIEQGNVNI 496 Query: 317 LVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAG 442 + + +K + + SFGELAL+YN PR+AS +A G Sbjct: 497 KI--NKEFKKCLDEFT---SFGELALLYNSPRSASAQAAQDG 533 Score = 34.7 bits (76), Expect = 1.2 Identities = 21/94 (22%), Positives = 46/94 (48%), Gaps = 1/94 (1%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 337 + + F + +Q + ++ GE ++ GDD ++FY+I++G V + ++ Sbjct: 565 LENVSFFSNFTHEQKDLLASQFTYQKFHKGETIVNIGDDANSFYIIKSG--QVSIISQNQ 622 Query: 338 VEKVVHTYEGSGSFGELALMYNMP-RAASVRAQT 436 +E+ + FGE +L N R +V+A++ Sbjct: 623 IEE--RQLQSGDWFGESSLYLNKSIRTRTVQAKS 654 >UniRef50_Q9FXQ0 Cluster: Cyclic nucreotide dependent protein kinase II; n=2; Chlamydomonas reinhardtii|Rep: Cyclic nucreotide dependent protein kinase II - Chlamydomonas reinhardtii Length = 718 Score = 64.1 bits (149), Expect = 2e-09 Identities = 35/107 (32%), Positives = 61/107 (57%), Gaps = 3/107 (2%) Frame = +2 Query: 140 ARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDG---DNFYVIENGVF 310 A + A+ +LLF LD+Q ++++ M+E+ G+ +I++GD G YV+++G F Sbjct: 46 AFIENALGRLLLFGKLDSQVQRKIVSEMYERTVPAGDILIKEGDTGLAACELYVVKSGKF 105 Query: 311 DVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 +VL + + V+ E FGE++LMY+ PR A+V A +W Sbjct: 106 EVLQKRQGQNVR-VNIKERGDCFGEISLMYDSPRTATVAATMDAVVW 151 Score = 49.6 bits (113), Expect = 4e-05 Identities = 29/103 (28%), Positives = 54/103 (52%) Frame = +2 Query: 128 DAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGV 307 + Q +++ + + + +L ++ +++DA E + G+ VI +GD GD FY+++ G Sbjct: 167 ETQVSQVELFLNSVPILANLSREERIRLVDAFEENTYQAGQKVIVEGDKGDLFYIVKEGE 226 Query: 308 FDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 V KV H ++ + F E AL+ + PR A+V A T Sbjct: 227 AIVYQNTPGGQRKVNHLFK-ADFFSERALLKDEPRMATVEAYT 268 >UniRef50_Q234E6 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 829 Score = 63.7 bits (148), Expect = 2e-09 Identities = 35/99 (35%), Positives = 57/99 (57%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 337 +R +F +L Q++ +++ MF + GE +I++ D+ F+++E G V V D Sbjct: 97 LRNHFVFYNLQDSQLETLVNEMFYCELQEGETIIKEEDNASTFFILEQGRIQVSVK--DN 154 Query: 338 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWG 454 V++ + EG FGELAL+YN PR+AS +A LWG Sbjct: 155 VKRDIVPGEG---FGELALLYNAPRSASCKALQKCHLWG 190 >UniRef50_UPI0000DB6E55 Cluster: PREDICTED: similar to cGMP-dependent protein kinase 21D CG3324-PA; n=2; Apocrita|Rep: PREDICTED: similar to cGMP-dependent protein kinase 21D CG3324-PA - Apis mellifera Length = 723 Score = 63.3 bits (147), Expect = 3e-09 Identities = 34/117 (29%), Positives = 61/117 (52%), Gaps = 1/117 (0%) Frame = +2 Query: 104 APA-VFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGD 280 AP+ V+ K + R ++ +A+ +L+ Q++ ++ AM+ K+ P VI++GD G Sbjct: 123 APSPVYEKDEKSRQQIRKAILENEFLGNLEENQVEALVSAMYSKQIPPNTLVIQEGDIGS 182 Query: 281 NFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 + YV G FD+ T+ +FGE+AL+YN R S++ + G +W Sbjct: 183 HLYVSAEGEFDIY-----EGNTFQRTFGPGVAFGEIALLYNTMRLRSIKVKKGGKVW 234 Score = 34.7 bits (76), Expect = 1.2 Identities = 15/47 (31%), Positives = 26/47 (55%) Frame = +2 Query: 254 VIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELAL 394 ++RQG+ G+ FY+I G + +D +E+ + FGELA+ Sbjct: 295 IVRQGEKGEKFYIISGGNVKITKDTEDGMEEELVVLGKGQYFGELAI 341 >UniRef50_Q31QH3 Cluster: Cyclic nucleotide-binding; n=2; Synechococcus elongatus|Rep: Cyclic nucleotide-binding - Synechococcus sp. (strain PCC 7942) (Anacystis nidulans R2) Length = 449 Score = 63.3 bits (147), Expect = 3e-09 Identities = 36/102 (35%), Positives = 57/102 (55%) Frame = +2 Query: 146 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 325 L +R + LFR D Q++ +++ + G+ + R+G+ G+ FY+I NG F V V Sbjct: 291 LPSLLRRVDLFRDYDDSQIRWLIEKGRRRTCVVGDVLCREGELGEEFYLILNGRFSVQVK 350 Query: 326 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 G E+ + T E FGELA+M ++PR A+V A G L+ Sbjct: 351 GR---EEAIATLESGNFFGELAVMLDIPRTATVVALEPGTLF 389 >UniRef50_Q22SE3 Cluster: Cyclic nucleotide-binding domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 451 Score = 63.3 bits (147), Expect = 3e-09 Identities = 34/110 (30%), Positives = 65/110 (59%) Frame = +2 Query: 122 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 301 KS + + + +++ +F +L ++++ V MF + EYV +Q D ++++IE+ Sbjct: 99 KSKSDQDLIMNSLKNHYVFYALTDEELEFVTQKMFYCENT-AEYVFKQEDKASSYFIIES 157 Query: 302 GVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 G D+++ +D V++ ++ E SFGELAL+YN PR+AS+R + W Sbjct: 158 GQVDIII--NDEVKRTLNPGE---SFGELALLYNAPRSASIRCKGNCHFW 202 Score = 50.8 bits (116), Expect = 2e-05 Identities = 27/86 (31%), Positives = 47/86 (54%) Frame = +2 Query: 176 FRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVH 355 F+S++++Q + A+ + GE ++ +GD D+F++I+ G V + +K + Sbjct: 234 FKSMNSEQKDSIASALINIKFMKGENIVNEGDAADSFFMIKEGTVSVW-----KDKKEIR 288 Query: 356 TYEGSGSFGELALMYNMPRAASVRAQ 433 SFGE AL + RAASVRA+ Sbjct: 289 KLGKGDSFGEQALYVSSKRAASVRAE 314 >UniRef50_A0D9C4 Cluster: Chromosome undetermined scaffold_42, whole genome shotgun sequence; n=8; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_42, whole genome shotgun sequence - Paramecium tetraurelia Length = 825 Score = 62.5 bits (145), Expect = 5e-09 Identities = 28/102 (27%), Positives = 57/102 (55%) Frame = +2 Query: 146 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 325 + ++ +G +F SL Q+ ++++ MF + +++ +QGD +++VIE G ++++ Sbjct: 117 IRKSFKGHFVFFSLPEDQIAKLIEHMFYCTLKANQFIFKQGDQASSYFVIEKGSVEIIIN 176 Query: 326 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 ++ + T FGE+AL+YN R+AS+R T W Sbjct: 177 -----DRQIRTLAEGSYFGEIALLYNATRSASIRTLTDCGFW 213 Score = 48.0 bits (109), Expect = 1e-04 Identities = 27/87 (31%), Positives = 44/87 (50%) Frame = +2 Query: 176 FRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVH 355 F + ++Q + A+ + PG+ ++ +GD D+FYVI++G VL G + K+ Sbjct: 245 FSFMTSEQKDSIAHALITTKFAPGQAIVNEGDQADSFYVIKSGEVSVL-KGTKEIRKM-- 301 Query: 356 TYEGSGSFGELALMYNMPRAASVRAQT 436 SFGE AL R A+ A+T Sbjct: 302 --GAKDSFGEQALYEKSKRGATCVAET 326 >UniRef50_Q0LLK2 Cluster: Stage II sporulation E; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Stage II sporulation E - Herpetosiphon aurantiacus ATCC 23779 Length = 570 Score = 62.1 bits (144), Expect = 7e-09 Identities = 37/108 (34%), Positives = 57/108 (52%) Frame = +2 Query: 125 SDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG 304 ++A A L E + + LF +D +Q ++ + R PGE + +GD GD+ Y++ G Sbjct: 142 TEASIAPLVEFLEQLPLFHEVDQATIQNLVQSAEHVRLAPGETLFSEGDSGDDCYIVMAG 201 Query: 305 VFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGAL 448 DV+ + G+ GE+AL+ N PRAASVRA+TA L Sbjct: 202 DVDVIKALATETILLERCRPGA-ILGEMALIDNSPRAASVRARTAATL 248 >UniRef50_A0DCJ0 Cluster: Chromosome undetermined scaffold_45, whole genome shotgun sequence; n=7; Oligohymenophorea|Rep: Chromosome undetermined scaffold_45, whole genome shotgun sequence - Paramecium tetraurelia Length = 775 Score = 62.1 bits (144), Expect = 7e-09 Identities = 30/94 (31%), Positives = 57/94 (60%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 352 +F +L +++ +++ MF + G Y+ +Q D F++++ G +V+V +++ ++ + Sbjct: 73 VFYNLSEAELENIVNKMFYCEAAAGAYIFKQQDHATCFFILQRGSLEVIV--NEKAKREL 130 Query: 353 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWG 454 T +G FGELAL+YN PR+ASV+ LWG Sbjct: 131 KTGDG---FGELALLYNAPRSASVKCFENCNLWG 161 Score = 52.8 bits (121), Expect = 4e-06 Identities = 33/104 (31%), Positives = 53/104 (50%) Frame = +2 Query: 122 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 301 K + + E VR F +L +Q + + ++ + ++ +GD G +FY+I+ Sbjct: 177 KEYEENRKFMEVVR---FFHNLTNEQKDAIAAVLIVQKFYKNQIIVNEGDPGSSFYIIKE 233 Query: 302 GVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQ 433 G VL G+ V K+ Y+G SFGE AL YN R +VRA+ Sbjct: 234 GTVSVL-KGNKEVRKL---YKGD-SFGEQALYYNTVRQMTVRAE 272 >UniRef50_UPI0000660D74 Cluster: Homolog of Homo sapiens "cGMP-dependent protein kinase 2; n=3; Coelomata|Rep: Homolog of Homo sapiens "cGMP-dependent protein kinase 2 - Takifugu rubripes Length = 93 Score = 61.7 bits (143), Expect = 9e-09 Identities = 31/92 (33%), Positives = 51/92 (55%) Frame = +2 Query: 152 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 331 +A+ L+ Q M Q++D MFE G+ VIR+G+ G+ YV+ G+ +V+ G Sbjct: 6 DAIMNNDFLNKLEPQHMNQMVDCMFENVYTEGQLVIREGEPGNYLYVLSEGLLEVIQNG- 64 Query: 332 DRVEKVVHTYEGSGSFGELALMYNMPRAASVR 427 K++ +FGELA++YN R A+V+ Sbjct: 65 ----KLLGEMHAGTAFGELAILYNCKRTATVK 92 >UniRef50_Q01E02 Cluster: CGMP-dependent protein kinase, putative; n=2; Ostreococcus|Rep: CGMP-dependent protein kinase, putative - Ostreococcus tauri Length = 935 Score = 55.6 bits (128), Expect = 6e-07 Identities = 36/88 (40%), Positives = 47/88 (53%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 352 LF +L QQ+ + +A + E + V RQGD G FY+IE G V V G +VV Sbjct: 248 LFNALSEQQLITISNAARRETYEARDEVFRQGDPGHCFYIIERGEVSVRVNG----AEVV 303 Query: 353 HTYEGSGSFGELALMYNMPRAASVRAQT 436 G FGE AL+ N PRAA++ A T Sbjct: 304 KLSRGD-FFGERALVNNEPRAATIYAMT 330 Score = 46.8 bits (106), Expect = 3e-04 Identities = 27/95 (28%), Positives = 48/95 (50%), Gaps = 3/95 (3%) Frame = +2 Query: 152 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG---VFDVLV 322 E + + + L +++Q + + + + E VI+QG+ GD +++E+G V D Sbjct: 477 ETLSKVPILSKLSPEEIQNLAEELTDVSFRANETVIKQGESGDAMFILESGEVEVIDEKT 536 Query: 323 TGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVR 427 K++ S FGEL L+ + PRAA+VR Sbjct: 537 LNTSGDPKLLCKLGPSSYFGELGLLNSDPRAATVR 571 Score = 45.6 bits (103), Expect(2) = 1e-08 Identities = 25/67 (37%), Positives = 36/67 (53%), Gaps = 1/67 (1%) Frame = +2 Query: 122 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDG-DNFYVIE 298 ++ A + A+ G LLF LDA ++V DAM + VI QGDD + FY+IE Sbjct: 78 RTTASEQAIERAMEGNLLFAELDAASRRRVADAMMPMYVGENDVVIAQGDDECERFYIIE 137 Query: 299 NGVFDVL 319 +G V+ Sbjct: 138 SGEASVM 144 Score = 35.9 bits (79), Expect(2) = 1e-08 Identities = 19/44 (43%), Positives = 23/44 (52%) Frame = +2 Query: 320 VTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 V D V T FGELAL+Y PR+A++ AQT LW Sbjct: 174 VVYDPATATCVATLGPGRGFGELALLYACPRSATIVAQTPMKLW 217 >UniRef50_A4S6U9 Cluster: Predicted protein; n=2; Ostreococcus|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 680 Score = 61.3 bits (142), Expect = 1e-08 Identities = 36/102 (35%), Positives = 53/102 (51%) Frame = +2 Query: 146 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 325 L EA+ F LDA ++V MF G ++ + + GD Y+I G FDVL Sbjct: 16 LCEALSQTFTFSELDANVRRRVASEMFFINVPEGTILMEEDEPGDALYLIAGGEFDVLQN 75 Query: 326 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 V+ +G GELAL+Y++PR+A+VRA+T +W Sbjct: 76 RLGADISVLTRTKGD-IIGELALLYSVPRSATVRAKTRSQVW 116 >UniRef50_Q16JU3 Cluster: Cgmp-dependent protein kinase; n=2; Endopterygota|Rep: Cgmp-dependent protein kinase - Aedes aegypti (Yellowfever mosquito) Length = 966 Score = 60.9 bits (141), Expect = 2e-08 Identities = 29/89 (32%), Positives = 50/89 (56%) Frame = +2 Query: 185 LDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYE 364 +D ++++ V DAM P Y+I++GD G +F+V +G ++V+ KV+ ++ Sbjct: 404 MDEERLKAVTDAMSPMTFPPNSYIIKEGDIGAHFFVSADGTYEVVAE-----NKVIKSFG 458 Query: 365 GSGSFGELALMYNMPRAASVRAQTAGALW 451 FGELA++Y R AS+R T +W Sbjct: 459 RGVVFGELAILYKAKRFASIRVTTEAKVW 487 Score = 60.1 bits (139), Expect = 3e-08 Identities = 29/92 (31%), Positives = 50/92 (54%) Frame = +2 Query: 167 ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEK 346 + + + L +++ ++ D + + G +I+QGD GD FY+I G +V+ T V+K Sbjct: 516 VSILKDLQTEKLHKISDLLKREFYATGSTIIQQGDPGDKFYIIRGGSVNVIKTDRHGVDK 575 Query: 347 VVHTYEGSGSFGELALMYNMPRAASVRAQTAG 442 +V T + FGE AL++ R AS+ A G Sbjct: 576 LVGTLQRGAYFGEQALLHEDRRLASIIANPPG 607 >UniRef50_Q8MMZ5 Cluster: CGMP-dependent protein kinase; n=2; Eimeria|Rep: CGMP-dependent protein kinase - Eimeria maxima Length = 1007 Score = 60.1 bits (139), Expect = 3e-08 Identities = 32/112 (28%), Positives = 65/112 (58%), Gaps = 1/112 (0%) Frame = +2 Query: 122 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 301 K+D+ + + ++ G L+ SL+ +++ + +A+ G+ V +QG++G F+++ + Sbjct: 164 KTDSDLSLIRSSLSGNLVCSSLNDSEVEALANAVQFFTFAKGDIVTKQGENGSYFFIVHS 223 Query: 302 GVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA-QTAGALWG 454 G F+V+V EKVV+ +FGE++L++N R A+++ ALWG Sbjct: 224 GEFEVIVN-----EKVVNKIVQGQAFGEISLIHNSARTATIKTLSDQAALWG 270 Score = 52.4 bits (120), Expect = 6e-06 Identities = 26/86 (30%), Positives = 49/86 (56%) Frame = +2 Query: 176 FRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVH 355 F+ L Q + +A+ + +PG+ ++++G+ GD Y+I++G V + G D V Sbjct: 301 FQMLTEAQKNVITNALVVQSFKPGQPIVKEGEKGDILYIIKSGKARVSIKGKD-----VR 355 Query: 356 TYEGSGSFGELALMYNMPRAASVRAQ 433 + FGE AL+Y+ PR+A++ A+ Sbjct: 356 LLQKGDYFGERALLYDEPRSATITAE 381 Score = 48.0 bits (109), Expect = 1e-04 Identities = 32/94 (34%), Positives = 49/94 (52%), Gaps = 1/94 (1%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 352 +FR L QQ Q ++ A R GE +IR+G+ G F++I+ G +L G + V Sbjct: 574 IFRYLSEQQTQTLIRAFKTVRYTQGEAIIREGEIGSRFFIIKLGEVAILKGG-----RRV 628 Query: 353 HTYEGSGSFGELALMYNMPRAASVRAQTAGA-LW 451 T FGE AL+++ R+A+V A + LW Sbjct: 629 RTLGRHDYFGERALLHDERRSATVAANSPEVDLW 662 >UniRef50_O76360 Cluster: Egg laying defective protein 4, isoform a; n=5; Caenorhabditis elegans|Rep: Egg laying defective protein 4, isoform a - Caenorhabditis elegans Length = 780 Score = 60.1 bits (139), Expect = 3e-08 Identities = 35/136 (25%), Positives = 67/136 (49%) Frame = +2 Query: 44 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 223 +R A + +P ++ + K+ + + +AV+ + L +Q+ ++++ M Sbjct: 158 QRAKKIAVSAEPTNFENKPATLQHYNKTVGAKQMIRDAVQKNDFLKQLAKEQIIELVNCM 217 Query: 224 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYN 403 +E R+ G++VI++G+ GD +V+ G V R ++ GELA++YN Sbjct: 218 YEMRARAGQWVIQEGEPGDRLFVVAEGELQV-----SREGALLGKMRAGTVMGELAILYN 272 Query: 404 MPRAASVRAQTAGALW 451 R ASV+A T LW Sbjct: 273 CTRTASVQALTDVQLW 288 Score = 52.8 bits (121), Expect = 4e-06 Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 1/104 (0%) Frame = +2 Query: 134 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 313 + ++L + + +F++L ++ ++ D M + + G Y+IRQG+ GD F+VI +G Sbjct: 306 RHSQLMNFLTKVSIFQNLSEDRISKMADVMDQDYYDGGHYIIRQGEKGDAFFVINSGQVK 365 Query: 314 VLVTGDDRVE-KVVHTYEGSGSFGELALMYNMPRAASVRAQTAG 442 V + E + + FGE AL+ R A++ AQ G Sbjct: 366 VTQQIEGETEPREIRVLNQGDFFGERALLGEEVRTANIIAQAPG 409 >UniRef50_UPI0000519F68 Cluster: PREDICTED: similar to cGMP-dependent protein kinase 21D CG3324-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to cGMP-dependent protein kinase 21D CG3324-PA - Apis mellifera Length = 639 Score = 59.7 bits (138), Expect = 4e-08 Identities = 38/139 (27%), Positives = 67/139 (48%), Gaps = 1/139 (0%) Frame = +2 Query: 38 NNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLD 217 N R+ SV E + S + VF K + + + A+ ++ + +++ ++ Sbjct: 30 NERKHSVIGEV-----NVSSDMPIKVFEKDEKTKNLIKNAILNNEFLKNFNESRIETLIS 84 Query: 218 AMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSG-SFGELAL 394 AM+ ++ + +I +G+ G + YV E G F + V + + GSG +FGELAL Sbjct: 85 AMYPRKVKANTRIIHEGETGSHLYVSEEGTFKIY------VNNIYNENFGSGVAFGELAL 138 Query: 395 MYNMPRAASVRAQTAGALW 451 +YN R S+ A T LW Sbjct: 139 LYNTKRLCSIDACTDAKLW 157 Score = 44.4 bits (100), Expect = 0.002 Identities = 23/82 (28%), Positives = 40/82 (48%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 337 VR I +F+ + + ++ D + + Y+IR+GD G+ FY+I+ G + + Sbjct: 183 VRQIEIFKDFSDEVLLKICDLIIVEFYPANSYIIREGDQGNKFYIIQGGHVKITKNKPND 242 Query: 338 VEKVVHTYEGSGSFGELALMYN 403 E+ + E FGE AL N Sbjct: 243 KEEELMILEKGDYFGEKALYDN 264 >UniRef50_Q6P5T7 Cluster: PRKG1 protein; n=14; Euteleostomi|Rep: PRKG1 protein - Homo sapiens (Human) Length = 312 Score = 59.7 bits (138), Expect = 4e-08 Identities = 39/137 (28%), Positives = 66/137 (48%), Gaps = 1/137 (0%) Frame = +2 Query: 44 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 223 +R+++ AE + D +PKS + + EA+ ++L+ Q+Q+++D M Sbjct: 75 KRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCM 134 Query: 224 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMY 400 + +I++GD G YV+E+G +V G V G G FGELA++Y Sbjct: 135 YPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILY 188 Query: 401 NMPRAASVRAQTAGALW 451 N R A+V+ LW Sbjct: 189 NCTRTATVKTLVNVKLW 205 Score = 50.0 bits (114), Expect = 3e-05 Identities = 28/82 (34%), Positives = 42/82 (51%), Gaps = 1/82 (1%) Frame = +2 Query: 152 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 331 E ++ + F+SL + + ++ D + E E GEY+IRQG GD F++I G +V Sbjct: 229 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 288 Query: 332 DRVEKVVHTYEGSGS-FGELAL 394 + V G G FGE AL Sbjct: 289 PSEDPVFLRTLGKGDWFGEKAL 310 >UniRef50_P14619 Cluster: cGMP-dependent protein kinase 1, beta isozyme; n=49; Bilateria|Rep: cGMP-dependent protein kinase 1, beta isozyme - Homo sapiens (Human) Length = 686 Score = 59.7 bits (138), Expect = 4e-08 Identities = 39/137 (28%), Positives = 66/137 (48%), Gaps = 1/137 (0%) Frame = +2 Query: 44 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 223 +R+++ AE + D +PKS + + EA+ ++L+ Q+Q+++D M Sbjct: 75 KRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCM 134 Query: 224 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMY 400 + +I++GD G YV+E+G +V G V G G FGELA++Y Sbjct: 135 YPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILY 188 Query: 401 NMPRAASVRAQTAGALW 451 N R A+V+ LW Sbjct: 189 NCTRTATVKTLVNVKLW 205 Score = 53.6 bits (123), Expect = 2e-06 Identities = 33/97 (34%), Positives = 48/97 (49%), Gaps = 1/97 (1%) Frame = +2 Query: 152 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 331 E ++ + F+SL + + ++ D + E E GEY+IRQG GD F++I G +V Sbjct: 229 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 288 Query: 332 DRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTA 439 + V G G FGE AL R A+V A A Sbjct: 289 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEA 325 >UniRef50_Q5RGL5 Cluster: Novel protein similar to vertebrate protein kinase, cGMP-dependent, type I; n=3; Danio rerio|Rep: Novel protein similar to vertebrate protein kinase, cGMP-dependent, type I - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 570 Score = 59.3 bits (137), Expect = 5e-08 Identities = 32/106 (30%), Positives = 55/106 (51%) Frame = +2 Query: 134 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 313 + +++ +A+ R LD +Q+ ++D M G+ +I++G +GD+ Y++ G Sbjct: 1 ETSQIVKAIGKNDFLRRLDEEQISMMVDLMKVLDCRAGDEIIKEGTEGDSMYIVAAGELK 60 Query: 314 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 V G D + FGELA++YN R ASV+A +A LW Sbjct: 61 VTQAGRD-----LRILSPGDMFGELAILYNCKRTASVKAISAVKLW 101 Score = 54.0 bits (124), Expect = 2e-06 Identities = 33/104 (31%), Positives = 58/104 (55%), Gaps = 1/104 (0%) Frame = +2 Query: 122 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 301 KS +R +L ++ ++L+ Q+ +++D+M E R + E ++R+G +G+ FY+I Sbjct: 115 KSKMKREQLMGFLKTARTLKALNDVQLSKIIDSMEEVRFQDNEVIVREGAEGNTFYIILK 174 Query: 302 GVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPRAASVRA 430 G +VLVT ++ G G FGELAL+ + R A+ A Sbjct: 175 G--EVLVTKKVNGQQKTIRKMGEGEHFGELALIREILRTATCTA 216 >UniRef50_A7PEK0 Cluster: Chromosome chr11 scaffold_13, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr11 scaffold_13, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 1049 Score = 59.3 bits (137), Expect = 5e-08 Identities = 33/63 (52%), Positives = 41/63 (65%), Gaps = 5/63 (7%) Frame = +2 Query: 278 DNFYVIENGVFDVLVTGDDR---VEKVVHTY--EGSGSFGELALMYNMPRAASVRAQTAG 442 D FYV+ +G F+VL T +++ V +V+ Y E SFGELALMYN P ASVRA T G Sbjct: 495 DCFYVVGSGEFEVLATQEEKNGEVTRVLQQYTAEKLSSFGELALMYNKPLQASVRAVTNG 554 Query: 443 ALW 451 LW Sbjct: 555 TLW 557 >UniRef50_O17474 Cluster: Cyclic GMP-dependent protein kinase; n=1; Hydra oligactis|Rep: Cyclic GMP-dependent protein kinase - Hydra oligactis (Hydra) Length = 742 Score = 58.8 bits (136), Expect = 7e-08 Identities = 30/97 (30%), Positives = 57/97 (58%), Gaps = 2/97 (2%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL--VTGD 331 + + +F++L + ++++ + E+ E GE+++R+G+ GD+FY+++ G+ VL + G Sbjct: 274 LHSVPVFKNLPNDTLLKIVEVIEEEFYEDGEFIVREGERGDSFYILKQGLVKVLQMIEGK 333 Query: 332 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAG 442 D ++ H +G FGE AL+ R ASV A G Sbjct: 334 DEPVEIRHLSQGE-YFGEKALLGEDVRTASVVASIGG 369 Score = 56.8 bits (131), Expect = 3e-07 Identities = 44/142 (30%), Positives = 76/142 (53%) Frame = +2 Query: 26 VARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQ 205 V N+R +V AE+ E + D P + PKS + +++AV + L+ Q++ Sbjct: 115 VKTVRNKRFAVSAES-GKELQNLD--FPKI-PKSTEVKEFISQAVLKNNFLKHLEECQVK 170 Query: 206 QVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGE 385 +++ M +K + GEY+I++GD G+ +V G+ ++ GD + K + E FGE Sbjct: 171 EIVLFMSQKSFKRGEYIIKEGDMGNALFVSYVGLLEI-SQGDKILGKPLRPGE---LFGE 226 Query: 386 LALMYNMPRAASVRAQTAGALW 451 LA++YN R ASV+A +W Sbjct: 227 LAILYNCTRTASVKAIDDVEVW 248 >UniRef50_Q2HGG6 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 345 Score = 58.8 bits (136), Expect = 7e-08 Identities = 37/109 (33%), Positives = 60/109 (55%), Gaps = 1/109 (0%) Frame = +2 Query: 113 VFPKSDAQRARLAEA-VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFY 289 + +S R R+ E + + L +L + ++ DA+ ++ G +IR+GD G +FY Sbjct: 196 ILMESTFARRRMYEGFLEEVPLLSTLTPYERSKIADALESQKFPAGHTIIREGDPGHSFY 255 Query: 290 VIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 ++E G +G+D V H Y+ FGELAL+ + PRAASV +QT Sbjct: 256 LLEAGEAVAYRSGND--TPVKH-YKKGDFFGELALLNDAPRAASVVSQT 301 >UniRef50_A4TWF8 Cluster: Na+/H+ Antiporter; n=1; Magnetospirillum gryphiswaldense|Rep: Na+/H+ Antiporter - Magnetospirillum gryphiswaldense Length = 868 Score = 58.0 bits (134), Expect = 1e-07 Identities = 31/92 (33%), Positives = 56/92 (60%), Gaps = 1/92 (1%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 337 V G+ LF++L +Q+ +++D + + PG+++IR+G+ GD + + +G +V T +R Sbjct: 730 VEGVPLFKTLSPEQLSRIIDLLHPMLAVPGDFIIRKGEVGDGMFFVASGAVEVR-TETNR 788 Query: 338 VEKVVHTYEGSGS-FGELALMYNMPRAASVRA 430 + + GSG FGE+AL+ + PR A V A Sbjct: 789 LRR------GSGDFFGEMALLSHAPRNADVVA 814 >UniRef50_Q9VL34 Cluster: CG4839-PA, isoform A; n=2; Sophophora|Rep: CG4839-PA, isoform A - Drosophila melanogaster (Fruit fly) Length = 1003 Score = 57.2 bits (132), Expect = 2e-07 Identities = 33/111 (29%), Positives = 57/111 (51%), Gaps = 1/111 (0%) Frame = +2 Query: 122 KSDAQRARLAEAV-RGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIE 298 K + R + A+ R L +D ++ + V++AM +IR+ ++G YV Sbjct: 414 KDEGTRNLIRTAIERNDFLNNLMDKERKEMVINAMAPASYRKHSLIIREHEEGSEIYVSA 473 Query: 299 NGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 G +DV+ G ++V ++ + FGELA++YN PR AS+ A T +W Sbjct: 474 EGQYDVIRGG-----QLVASFGPATVFGELAILYNAPRQASIEAATDARVW 519 Score = 46.8 bits (106), Expect = 3e-04 Identities = 27/103 (26%), Positives = 48/103 (46%) Frame = +2 Query: 134 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 313 +R + +R + D + +V+D + K E ++R+G+ G+ FY+I G Sbjct: 537 EREENLQFLRSAPFLQEFDQSLLLKVVDLLQRKFYETDSCIVREGELGNEFYIIRCGTVT 596 Query: 314 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAG 442 + + + E++V + FGE AL+ R ASV A G Sbjct: 597 IKKLDEQQQEQIVANRKRGDYFGEQALLNADVRQASVYADAPG 639 >UniRef50_A0YP22 Cluster: Putative uncharacterized protein; n=1; Lyngbya sp. PCC 8106|Rep: Putative uncharacterized protein - Lyngbya sp. PCC 8106 Length = 478 Score = 56.8 bits (131), Expect = 3e-07 Identities = 25/95 (26%), Positives = 58/95 (61%) Frame = +2 Query: 146 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 325 L + ++ + F++ + ++Q+++ + K+ + E+++R+G+ G+ FY+I +G + + Sbjct: 311 LKDILKKVCYFKTCNDFHLRQLIELGYRKQFQASEFILREGETGERFYIILSGSVEAYLE 370 Query: 326 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 430 DR V++T+ FGE +LM +P+ AS+R+ Sbjct: 371 KVDRQIDVLNTH---NFFGEFSLMLGVPQPASIRS 402 >UniRef50_Q23DN8 Cluster: Cyclic nucleotide-binding domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 808 Score = 56.8 bits (131), Expect = 3e-07 Identities = 30/88 (34%), Positives = 49/88 (55%) Frame = +2 Query: 191 AQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGS 370 AQ+++ + MF +++ +Q D+ +F+++E G +V+V EK + Sbjct: 92 AQRVELTIK-MFYCEVPMNDFIFKQSDNATSFFILERGAMEVIVN-----EKSKRELKAG 145 Query: 371 GSFGELALMYNMPRAASVRAQTAGALWG 454 FGELAL+YN PR+ASV+A LWG Sbjct: 146 DGFGELALLYNAPRSASVKALDHCYLWG 173 Score = 46.0 bits (104), Expect = 5e-04 Identities = 31/104 (29%), Positives = 51/104 (49%) Frame = +2 Query: 122 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 301 K + + E VR F +L +Q + + ++ + ++ +GD +FY+I+ Sbjct: 189 KEYEENRKFMEVVR---FFHNLTNEQKDAIAAVLIVQKFYKNQVIVTEGDPASSFYIIKE 245 Query: 302 GVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQ 433 G V G+ V K+ Y+G SFGE AL YN R +VRA+ Sbjct: 246 GNVTVW-KGNKEVRKL---YKGD-SFGEQALYYNTVRQMTVRAE 284 >UniRef50_Q8DKN0 Cluster: Tlr0829 protein; n=1; Synechococcus elongatus|Rep: Tlr0829 protein - Synechococcus elongatus (Thermosynechococcus elongatus) Length = 594 Score = 56.4 bits (130), Expect = 3e-07 Identities = 36/110 (32%), Positives = 59/110 (53%), Gaps = 1/110 (0%) Frame = +2 Query: 104 APAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDN 283 APA P+ L +R I F ++Q +++ + GE + R+GD GD Sbjct: 421 APAA-PEMAKAEPSLTNLLRNISCFSRCSNAELQMLIELGNREFYTVGEVICREGDPGDA 479 Query: 284 FYVIENGVFDVLVTGDDRVEKVVHT-YEGSGSFGELALMYNMPRAASVRA 430 FY+I G +V +++ +++ T YEG FGE+A++ MPR+A+VRA Sbjct: 480 FYIILEGSVEV---RSEQLNQILATLYEGE-FFGEIAVLTGMPRSATVRA 525 >UniRef50_Q4Q2R2 Cluster: Regulatory subunit of protein kinase a-like protein; n=3; Leishmania|Rep: Regulatory subunit of protein kinase a-like protein - Leishmania major Length = 648 Score = 56.4 bits (130), Expect = 3e-07 Identities = 33/120 (27%), Positives = 61/120 (50%), Gaps = 3/120 (2%) Frame = +2 Query: 89 DSDEGAPAVFPKSDAQRARLAEAVRGIL---LFRSLDAQQMQQVLDAMFEKRSEPGEYVI 259 D DE A FP + + ++ R ++ LF +LD + + M ++ E G ++ Sbjct: 335 DIDEARIASFPTTPKSQEKMKTISRVLVRHFLFSTLDDSDIAKFASIMDVEKFEAGTQIL 394 Query: 260 RQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTA 439 +G D F+++ +G + + +D E VV GS +FG+L LMY + A+V A+++ Sbjct: 395 EKGHTNDTFFIVLDGEAETTMMNEDGAEVVVPLVRGS-TFGDLGLMYEISNGAAVVARSS 453 >UniRef50_A0BE58 Cluster: Chromosome undetermined scaffold_101, whole genome shotgun sequence; n=17; Oligohymenophorea|Rep: Chromosome undetermined scaffold_101, whole genome shotgun sequence - Paramecium tetraurelia Length = 823 Score = 56.4 bits (130), Expect = 3e-07 Identities = 28/83 (33%), Positives = 49/83 (59%) Frame = +2 Query: 203 QQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFG 382 + ++ MF R E+V +Q D +++I+ GV ++++ G+ V+K + T +G FG Sbjct: 135 EDIVMKMFYCRVAGNEFVFQQNDQASAYFIIDQGVCEIIINGE--VKKQLSTGDG---FG 189 Query: 383 ELALMYNMPRAASVRAQTAGALW 451 ELAL+Y PR+ASV+ + W Sbjct: 190 ELALLYGAPRSASVKTKDECFFW 212 Score = 42.3 bits (95), Expect = 0.006 Identities = 22/91 (24%), Positives = 45/91 (49%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 337 + I F + Q + A+ ++ + G+ ++ +GD ++++I++G+ ++ G++ Sbjct: 238 IDSIKFFEWMTVDQKDMIAGAIIAQQFKKGQAIVNEGDMASSYFIIKSGMVKIMKGGNE- 296 Query: 338 VEKVVHTYEGSGSFGELALMYNMPRAASVRA 430 + SFGE AL N R ASV A Sbjct: 297 ----LRQMSAGDSFGEQALYQNSVRGASVIA 323 >UniRef50_Q8SRB5 Cluster: CAMP-DEPENDENT PROTEIN KINASE TYPE 1 REGULATORY CHAIN; n=1; Encephalitozoon cuniculi|Rep: CAMP-DEPENDENT PROTEIN KINASE TYPE 1 REGULATORY CHAIN - Encephalitozoon cuniculi Length = 312 Score = 56.4 bits (130), Expect = 3e-07 Identities = 37/137 (27%), Positives = 72/137 (52%) Frame = +2 Query: 41 NRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDA 220 +RR V++E PE + +PK + L+ + + F L+ +Q +++++ Sbjct: 79 SRRSGVYSERITPETFRLN-----YYPKDEETIRFLSSILVSDIPFGFLNPEQKTRLIES 133 Query: 221 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 400 + G +V+ +G+ G Y++ +G F+V G + K+ +G FGE+AL++ Sbjct: 134 TELIEIKRGTFVMHEGEIGSQMYIVASGEFEV-TKGGTLLRKLT---KGC-FFGEIALLH 188 Query: 401 NMPRAASVRAQTAGALW 451 N+PR A+V+A T G +W Sbjct: 189 NIPRTATVKAVTDGKVW 205 >UniRef50_Q4SL71 Cluster: Chromosome 17 SCAF14563, whole genome shotgun sequence; n=4; Tetraodontidae|Rep: Chromosome 17 SCAF14563, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 726 Score = 56.0 bits (129), Expect = 5e-07 Identities = 36/130 (27%), Positives = 65/130 (50%), Gaps = 1/130 (0%) Frame = +2 Query: 44 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 223 +R+++ AE + D +PKS + + EA+ ++L+ Q+Q+++D M Sbjct: 73 KRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCM 132 Query: 224 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMY 400 + +I++GD G YV+E+G +V E + G G FGELA++Y Sbjct: 133 YPVEYGKDSCIIKEGDVGSLVYVMEDGKVEV------TKESLKLCTMGPGKVFGELAILY 186 Query: 401 NMPRAASVRA 430 N R A+V++ Sbjct: 187 NCTRTATVKS 196 Score = 52.0 bits (119), Expect = 7e-06 Identities = 33/97 (34%), Positives = 46/97 (47%), Gaps = 1/97 (1%) Frame = +2 Query: 152 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 331 E ++ + F+ L + ++ D + E E GEY+IRQG GD F++I G +V Sbjct: 269 EFLKSVPTFQGLQEDILSKLADVLEETHYEDGEYIIRQGARGDTFFIISKGKVNVTREDS 328 Query: 332 DRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTA 439 E V G G FGE AL R A+V A A Sbjct: 329 PNGEPVYLRSLGKGDWFGEKALQGEDIRTANVIAAEA 365 >UniRef50_Q8CXT1 Cluster: CAMP-dependent protein kinase regulatory chain; n=4; Leptospira|Rep: CAMP-dependent protein kinase regulatory chain - Leptospira interrogans Length = 719 Score = 55.6 bits (128), Expect = 6e-07 Identities = 33/112 (29%), Positives = 59/112 (52%), Gaps = 2/112 (1%) Frame = +2 Query: 107 PAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNF 286 P + P + L + + I +F ++ ++ L + E+R + G+ +IR+G GD F Sbjct: 450 PEITPPKHIEAYNLLDVLTQIDIFHGFPIEKAKEFLLIVNEERYKRGDQIIRKGTPGDKF 509 Query: 287 YVIENG--VFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 Y+I +G F+ L D+ + + Y FGE +L+ ++PRAA V A+T Sbjct: 510 YIIASGNVKFEGL-NQDETGQGPIKRYGTYEYFGEASLVLDLPRAADVYAET 560 >UniRef50_A5GVU5 Cluster: ABC-type multidrug transport system, ATPase and permease components; n=1; Synechococcus sp. RCC307|Rep: ABC-type multidrug transport system, ATPase and permease components - Synechococcus sp. (strain RCC307) Length = 718 Score = 55.2 bits (127), Expect = 8e-07 Identities = 37/115 (32%), Positives = 60/115 (52%), Gaps = 4/115 (3%) Frame = +2 Query: 116 FPKSDAQRARL-AEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYV 292 F S + R R+ A+ + I LF ++ ++ + +R PGE V R+GD D+FYV Sbjct: 576 FDISASHRVRITADRLASIPLFHGVEKAVLRWLAAEFVSERVRPGEEVFREGDPPDSFYV 635 Query: 293 IENGVFDVL---VTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGAL 448 + G +VL + G +++ V E FG+ L+ + PRA +VRA+ G L Sbjct: 636 VVAGTLEVLQDDLWGGVPIKQGV--VEEGDFFGDAGLLEDRPRAVTVRARGEGLL 688 >UniRef50_Q4RR21 Cluster: Chromosome 14 SCAF15003, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 14 SCAF15003, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 621 Score = 54.8 bits (126), Expect = 1e-06 Identities = 27/80 (33%), Positives = 43/80 (53%) Frame = +2 Query: 185 LDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYE 364 LD +Q ++D + +PG +VI++G +GD+ Y++ G V G D + T Sbjct: 16 LDDEQTAMMVDLLAVSNFKPGSHVIKEGSEGDSMYIVAGGQLQVTQAGRD-----LRTLT 70 Query: 365 GSGSFGELALMYNMPRAASV 424 FGELA++YN R A+V Sbjct: 71 TGDVFGELAILYNCKRTATV 90 Score = 44.0 bits (99), Expect = 0.002 Identities = 28/104 (26%), Positives = 56/104 (53%), Gaps = 1/104 (0%) Frame = +2 Query: 122 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 301 KS +R +L ++ + L+ Q+ +++D+M E + + + ++R+G + + FY+I Sbjct: 147 KSKKRREQLMGFLKMSQTLKDLNNVQLSKIIDSMEEVKYQDKDVIVREGAEANTFYIILK 206 Query: 302 GVFDVLVTGD-DRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 430 G +VLVT + + +K + FGE AL+ + R A+ A Sbjct: 207 G--EVLVTKNVNGHQKQIRRMGKGEHFGEQALIREVLRTATCTA 248 >UniRef50_A3IKE0 Cluster: Putative uncharacterized protein; n=1; Cyanothece sp. CCY 0110|Rep: Putative uncharacterized protein - Cyanothece sp. CCY 0110 Length = 493 Score = 54.8 bits (126), Expect = 1e-06 Identities = 30/96 (31%), Positives = 55/96 (57%) Frame = +2 Query: 146 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 325 + E + + F++LD Q++++++ K + E + ++ D GD FY+I +G ++ Sbjct: 327 IKELLSKVEYFKTLDDLQIRKLIEIGTLKELKQNEILFKENDPGDAFYIILSGSVEIFTE 386 Query: 326 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQ 433 ++ ++ Y G FGELALM +PR ASV+AQ Sbjct: 387 TLNKTLAIL--YRGD-FFGELALMLGIPRTASVKAQ 419 >UniRef50_A0E0G1 Cluster: Chromosome undetermined scaffold_71, whole genome shotgun sequence; n=5; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_71, whole genome shotgun sequence - Paramecium tetraurelia Length = 779 Score = 54.8 bits (126), Expect = 1e-06 Identities = 31/93 (33%), Positives = 48/93 (51%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 352 +F LD ++++ M+ S+ E+V +QGD F++IE G + + E+ Sbjct: 94 MFAQLDNNDKAKLIEEMYYVTSKDQEFVFKQGDKATLFFIIERGQCQITIN-----EEKK 148 Query: 353 HTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 + S FGELALMY+ PR+ASV A W Sbjct: 149 RVLKPSEFFGELALMYHAPRSASVIAIGDCGFW 181 Score = 42.7 bits (96), Expect = 0.005 Identities = 24/93 (25%), Positives = 44/93 (47%) Frame = +2 Query: 152 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 331 E + + F + +Q + + + + + GE ++ +GD ++FY+I+ G V G Sbjct: 205 EFLAQVKFFDFMTEEQRDSIANVLITLKFKQGESIVNEGDMANSFYIIQKGTVQVTKQG- 263 Query: 332 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 430 + + SFGE AL N R A+V+A Sbjct: 264 ----QFLRYMNQGDSFGEQALFGNCVRGATVKA 292 >UniRef50_Q08V69 Cluster: PKA regulatory subunit-like protein; n=1; Stigmatella aurantiaca DW4/3-1|Rep: PKA regulatory subunit-like protein - Stigmatella aurantiaca DW4/3-1 Length = 450 Score = 54.4 bits (125), Expect = 1e-06 Identities = 32/94 (34%), Positives = 49/94 (52%) Frame = +2 Query: 167 ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEK 346 I LF SL + ++L + + GE ++++G G + +VI G +V+ G + Sbjct: 177 IPLFASLGREMFLEMLAGVERSVFQRGERILQEGAPGSSMFVIVEGEVNVVRQGQEGQPL 236 Query: 347 VVHTYEGSGSFGELALMYNMPRAASVRAQTAGAL 448 V T G FGE+AL+Y +PR ASV A T L Sbjct: 237 TVATLGEGGFFGEMALLYPVPRLASVVAGTRTVL 270 >UniRef50_A7BXC8 Cluster: MscS Mechanosensitive ion channel; n=1; Beggiatoa sp. PS|Rep: MscS Mechanosensitive ion channel - Beggiatoa sp. PS Length = 564 Score = 54.4 bits (125), Expect = 1e-06 Identities = 27/66 (40%), Positives = 38/66 (57%) Frame = +2 Query: 233 RSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPR 412 R PG+ +++QGD GD+ ++I GV VLV DD K V FGE+AL+ R Sbjct: 424 RFNPGDTIVQQGDAGDSLFIIVEGVVSVLVQTDDGRTKEVARLGAGNFFGEMALLTGEER 483 Query: 413 AASVRA 430 A+V+A Sbjct: 484 MATVKA 489 >UniRef50_Q3MD80 Cluster: Cyclic nucleotide-binding domain (CNMP-BD) protein; n=1; Anabaena variabilis ATCC 29413|Rep: Cyclic nucleotide-binding domain (CNMP-BD) protein - Anabaena variabilis (strain ATCC 29413 / PCC 7937) Length = 408 Score = 54.0 bits (124), Expect = 2e-06 Identities = 28/83 (33%), Positives = 45/83 (54%) Frame = +2 Query: 182 SLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTY 361 +L +Q+ Q+L + +PGE VI QGD D FY++ G +V+ D K++ Sbjct: 236 TLTDKQLIQLLPQLKMLTFQPGEIVIHQGDLADKFYILMEGEVEVIQEDGDSEPKLLKRL 295 Query: 362 EGSGSFGELALMYNMPRAASVRA 430 + FGE+ L++ R A+VRA Sbjct: 296 GPNSYFGEIGLLHETTRTATVRA 318 >UniRef50_A7C147 Cluster: cGMP-dependent protein kinase type I; n=1; Beggiatoa sp. PS|Rep: cGMP-dependent protein kinase type I - Beggiatoa sp. PS Length = 387 Score = 54.0 bits (124), Expect = 2e-06 Identities = 34/104 (32%), Positives = 57/104 (54%), Gaps = 2/104 (1%) Frame = +2 Query: 143 RLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV 322 R + +R R L A+ + + + M +++ GE ++R+G+ GD FY+I++G ++ Sbjct: 131 RRMDKLRHFPALRRLPAESIYEAVHRMKIIKAKAGEIIVREGELGDAFYLIDSGRVEIWQ 190 Query: 323 TG--DDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGAL 448 TG DD+ +V EG +FGE AL+ R A+VR G L Sbjct: 191 TGFYDDKPTRVTELGEGD-AFGEDALVTGGRRNATVRMIEEGQL 233 >UniRef50_Q6WL05 Cluster: Hyperpolarization-activated ion channel; n=10; Pancrustacea|Rep: Hyperpolarization-activated ion channel - Panulirus argus (Spiny lobster) Length = 691 Score = 53.2 bits (122), Expect = 3e-06 Identities = 30/94 (31%), Positives = 53/94 (56%), Gaps = 1/94 (1%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 337 V + F + DA+ + V+ + + +PG+ +I++G G+ Y I+ G+ D++++ + Sbjct: 429 VASVPFFANADARFVTDVVTKLRYEVYQPGDIIIKEGTIGNKMYFIQEGIVDIVMSNGE- 487 Query: 338 VEKVVHTYEGSGS-FGELALMYNMPRAASVRAQT 436 V T GS FGE+ L+ N R ASVRA+T Sbjct: 488 ----VATSLSDGSYFGEICLLTNARRTASVRAET 517 >UniRef50_Q5QFC4 Cluster: EnvDll2-01; n=1; Oikopleura dioica|Rep: EnvDll2-01 - Oikopleura dioica (Tunicate) Length = 703 Score = 53.2 bits (122), Expect = 3e-06 Identities = 30/83 (36%), Positives = 48/83 (57%), Gaps = 1/83 (1%) Frame = +2 Query: 185 LDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYE 364 L ++++ D + E+R + + +I+QG+ GDNFY+I G + V D EK V + Sbjct: 280 LKESNLRKIADCLEEERFDDKDPIIKQGEVGDNFYIIRTGSVRITVNTDGDEEKEV-AVK 338 Query: 365 GSGS-FGELALMYNMPRAASVRA 430 G G FGE AL+ + R+A+V A Sbjct: 339 GEGEFFGEKALLTSDTRSANVYA 361 Score = 52.4 bits (120), Expect = 6e-06 Identities = 36/113 (31%), Positives = 58/113 (51%), Gaps = 3/113 (2%) Frame = +2 Query: 122 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVI--RQGDDGDNFYVI 295 K+ QR + +A+ R L Q+ ++DAM + E +I R+ GD ++I Sbjct: 140 KTAEQRKLIKDALLKNSFMRGLSEDQLNMLIDAMSKIDYPATEKIIKDRENTTGDEMFII 199 Query: 296 ENGVFDVLVTGDDRVEKVVHTYE-GSGSFGELALMYNMPRAASVRAQTAGALW 451 E+G +V ++ D H + SG FGELA+MYN R A++ ++T LW Sbjct: 200 EDG--EVTISKDG-----THITDIKSGLFGELAIMYNCQRTATITSKTDVTLW 245 >UniRef50_Q4QGD8 Cluster: Protein kinase A regulatory subunit, putative; n=7; Trypanosomatidae|Rep: Protein kinase A regulatory subunit, putative - Leishmania major Length = 502 Score = 52.8 bits (121), Expect = 4e-06 Identities = 41/132 (31%), Positives = 64/132 (48%), Gaps = 1/132 (0%) Frame = +2 Query: 44 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 223 RR++V E DPE + P V KS + + + +LF L ++ + V AM Sbjct: 203 RRQTVRVEGIDPEA--AKNYVPPVHEKSQEDTDMICKLLSHNVLFGFLGSKDILTVAGAM 260 Query: 224 FEKRSEPGEYVIRQGDDG-DNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 400 + + E +I G D YVI++G DV+ G +KV EG+ + GEL L+Y Sbjct: 261 YREEFVKDERIIEFGQTHCDKLYVIQSGEADVIKEG----QKVFVKTEGT-AVGELELLY 315 Query: 401 NMPRAASVRAQT 436 + P A+V+ T Sbjct: 316 DTPAVATVKVST 327 Score = 39.5 bits (88), Expect = 0.043 Identities = 22/86 (25%), Positives = 38/86 (44%) Frame = +2 Query: 179 RSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHT 358 +SLDA + Q+ DA+ G+Y+I ++G+ Y+I G +V+ + V Sbjct: 366 QSLDAYERMQIADALTSDEFAAGDYIIHYDEEGEWLYIIIEGTVEVIGRDAAGNKTKVCE 425 Query: 359 YEGSGSFGELALMYNMPRAASVRAQT 436 + GEL + A + A T Sbjct: 426 FHSGDHIGELEFLNKHRTVADIVAVT 451 >UniRef50_Q4QF64 Cluster: Protein kinase, putative; n=2; Leishmania|Rep: Protein kinase, putative - Leishmania major Length = 2689 Score = 52.8 bits (121), Expect = 4e-06 Identities = 45/153 (29%), Positives = 69/153 (45%), Gaps = 9/153 (5%) Frame = +2 Query: 20 PPVARFNNRRKSVFAETYDPEEDDSDEGAPA-------VFPKSDAQRARLAEAVRGILLF 178 P + RR +V A P + E +PA V PKS A+ +L +R F Sbjct: 301 PTGGQCQGRRLAVSAAPCMPPPEIIGEDSPATALPPLRVVPKSPAEEQQLRRLLRRCHSF 360 Query: 179 RSLDAQQMQQVLDAMFEKRSEPGEYVIRQGD-DGDNFYVIENGVFDVLVTGDDRVEKVVH 355 SL+A ++ VL AM ++ G ++ QG + Y++ G + + G K + Sbjct: 361 SSLEADTLESVLKAMDKEVHAAGAAILEQGQATTEKLYLVGEGTCEAIKNG-----KSLG 415 Query: 356 TYEGSGSFGELALMYNMPR-AASVRAQTAGALW 451 + G+FGEL LMY AA+VR T L+ Sbjct: 416 PLQPGGTFGELELMYKQAMCAATVRCVTRCVLY 448 >UniRef50_Q9M8S6 Cluster: Potassium channel SKOR (Stelar K(+) outward rectifying channel); n=25; Magnoliophyta|Rep: Potassium channel SKOR (Stelar K(+) outward rectifying channel) - Arabidopsis thaliana (Mouse-ear cress) Length = 828 Score = 52.8 bits (121), Expect = 4e-06 Identities = 25/90 (27%), Positives = 50/90 (55%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 337 + + LFR ++ + Q++ + E+ PGE ++ QG D Y + +GV + + D Sbjct: 398 IEKVPLFRGCSSEFINQIVIRLHEEFFLPGEVIMEQGSVVDQLYFVCHGVLEEIGITKDG 457 Query: 338 VEKVVHTYEGSGSFGELALMYNMPRAASVR 427 E++V + SFGE++++ N+P+ +VR Sbjct: 458 SEEIVAVLQPDHSFGEISILCNIPQPYTVR 487 >UniRef50_UPI0000383B9A Cluster: COG0642: Signal transduction histidine kinase; n=1; Magnetospirillum magnetotacticum MS-1|Rep: COG0642: Signal transduction histidine kinase - Magnetospirillum magnetotacticum MS-1 Length = 385 Score = 52.0 bits (119), Expect = 7e-06 Identities = 26/87 (29%), Positives = 47/87 (54%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 352 LF D + +++++ E GE + R+GD GD+ YV+ +G ++ V V+ Sbjct: 16 LFTVQDEETLKRIIACGSEVLLSDGECLFRKGDMGDSIYVVLDGAIEISVQDGGGEFHVM 75 Query: 353 HTYEGSGSFGELALMYNMPRAASVRAQ 433 + E FGE+A++ N+PR A+ A+ Sbjct: 76 NVLEVGSLFGEVAILDNLPRTANAAAR 102 >UniRef50_Q5WUW4 Cluster: Putative uncharacterized protein; n=4; Legionella pneumophila|Rep: Putative uncharacterized protein - Legionella pneumophila (strain Lens) Length = 153 Score = 52.0 bits (119), Expect = 7e-06 Identities = 24/92 (26%), Positives = 49/92 (53%), Gaps = 5/92 (5%) Frame = +2 Query: 170 LLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV-----TGDD 334 +LF+ +D + + + L+ E GE++ Q + GD+ Y++E G +++ D Sbjct: 10 MLFKGVDGKYIDEFLENCEEVELPQGEFLFHQNEIGDSMYIVEQGELQIILEQNSTDSDT 69 Query: 335 RVEKVVHTYEGSGSFGELALMYNMPRAASVRA 430 + E+++ ++ GEL + + RAAS+RA Sbjct: 70 KEEQLIGVFKSGSLVGELCVFGQLKRAASIRA 101 >UniRef50_Q1D8K7 Cluster: Mechanosensitive ion channel/cyclic nucleotide-binding domain protein; n=2; Cystobacterineae|Rep: Mechanosensitive ion channel/cyclic nucleotide-binding domain protein - Myxococcus xanthus (strain DK 1622) Length = 525 Score = 52.0 bits (119), Expect = 7e-06 Identities = 38/112 (33%), Positives = 61/112 (54%), Gaps = 6/112 (5%) Frame = +2 Query: 113 VFPKSDAQRARLAE-AVRGIL----LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDG 277 V + + R L+E +R +L LF+SLD +++ ++ +R GE +I++GD+G Sbjct: 343 VHVRQEMARTELSEDTIRSLLGAVDLFQSLDTEELDRLRQESLVRRFGAGERIIQEGDEG 402 Query: 278 DNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPRAASVRA 430 FYV+ +G V TG + E T G GS FGE+ L+ R+A+V A Sbjct: 403 RTFYVLASGEVSVR-TGKSQSEV---TRLGRGSYFGEMCLLTGERRSATVVA 450 >UniRef50_Q9Y3Q4 Cluster: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4; n=41; Euteleostomi|Rep: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 - Homo sapiens (Human) Length = 1203 Score = 52.0 bits (119), Expect = 7e-06 Identities = 31/93 (33%), Positives = 48/93 (51%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 337 V + LF + D + +L + + +PG+Y+IR+G G Y I++GV VL G+ Sbjct: 590 VASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKE 649 Query: 338 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 + +Y FGE+ L+ R ASVRA T Sbjct: 650 TKLADGSY-----FGEICLLTRGRRTASVRADT 677 >UniRef50_Q4S874 Cluster: Chromosome 5 SCAF14709, whole genome shotgun sequence; n=5; Clupeocephala|Rep: Chromosome 5 SCAF14709, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1512 Score = 51.6 bits (118), Expect = 1e-05 Identities = 33/93 (35%), Positives = 49/93 (52%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 337 V + LF + D + +L + + +PG+Y+IR+G G Y I++GV VL G+ Sbjct: 704 VASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGN-- 761 Query: 338 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 K +GS FGE+ L+ R ASVRA T Sbjct: 762 --KETKLSDGS-YFGEICLLTRGRRTASVRADT 791 Score = 40.7 bits (91), Expect = 0.019 Identities = 21/71 (29%), Positives = 37/71 (52%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 337 V + LF + D + +L + + +PG+Y+IR+G G Y I++GV VL G+ Sbjct: 562 VASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKE 621 Query: 338 VEKVVHTYEGS 370 + +Y G+ Sbjct: 622 TKLSDGSYFGA 632 >UniRef50_A5G0B9 Cluster: Putative transcriptional regulator, Crp/Fnr family; n=1; Acidiphilium cryptum JF-5|Rep: Putative transcriptional regulator, Crp/Fnr family - Acidiphilium cryptum (strain JF-5) Length = 227 Score = 51.6 bits (118), Expect = 1e-05 Identities = 29/94 (30%), Positives = 48/94 (51%) Frame = +2 Query: 167 ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEK 346 I LF +++ + +E+ GE +I++GD G + +I G V++ G D ++ Sbjct: 12 IPLFAPFSPEELDALYACTYERNMTTGEMLIQRGDPGTSMMLILAGEVRVVLPGIDGNDQ 71 Query: 347 VVHTYEGSGSFGELALMYNMPRAASVRAQTAGAL 448 ++T FGE+AL PR+A V A T G L Sbjct: 72 DLNTLREGAVFGEIALFDGKPRSADVVAATNGRL 105 >UniRef50_UPI0000EC9F34 Cluster: UPI0000EC9F34 related cluster; n=1; Gallus gallus|Rep: UPI0000EC9F34 UniRef100 entry - Gallus gallus Length = 747 Score = 51.2 bits (117), Expect = 1e-05 Identities = 32/93 (34%), Positives = 50/93 (53%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 337 V + LF + D + +L + + +PG+Y+IR+G G Y I++GV +L G+ Sbjct: 392 VASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSILTKGN-- 449 Query: 338 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 K + +GS FGE+ L+ R ASVRA T Sbjct: 450 --KEMKLSDGS-YFGEICLLTRGRRTASVRADT 479 >UniRef50_A1Z9N7 Cluster: CG8585-PE, isoform E; n=18; Pancrustacea|Rep: CG8585-PE, isoform E - Drosophila melanogaster (Fruit fly) Length = 1327 Score = 51.2 bits (117), Expect = 1e-05 Identities = 30/94 (31%), Positives = 50/94 (53%), Gaps = 1/94 (1%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 337 V + F + D+ + V+ + + +PG+ +I++G G Y I+ GV D+++ + Sbjct: 1119 VASVPFFANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGE- 1177 Query: 338 VEKVVHTYEGSGS-FGELALMYNMPRAASVRAQT 436 V T GS FGE+ L+ N R ASVRA+T Sbjct: 1178 ----VATSLSDGSYFGEICLLTNARRVASVRAET 1207 >UniRef50_UPI000038CAE7 Cluster: COG1012: NAD-dependent aldehyde dehydrogenases; n=1; Nostoc punctiforme PCC 73102|Rep: COG1012: NAD-dependent aldehyde dehydrogenases - Nostoc punctiforme PCC 73102 Length = 639 Score = 50.8 bits (116), Expect = 2e-05 Identities = 25/79 (31%), Positives = 43/79 (54%), Gaps = 1/79 (1%) Frame = +2 Query: 203 QQVLDAMFEKRS-EPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF 379 Q VL+ + + S G Y+ ++G D+ Y++E G+ + + VV+ E F Sbjct: 20 QMVLEKIMQPVSFSAGTYIFKEGSFADSCYILEEGIVRIETASESSSNFVVNYLEAGTIF 79 Query: 380 GELALMYNMPRAASVRAQT 436 GE++L+ MPR+A+ AQT Sbjct: 80 GEISLLDKMPRSATAYAQT 98 >UniRef50_Q2RX44 Cluster: Cyclic nucleotide-binding domain (CNMP-BD) protein; n=1; Rhodospirillum rubrum ATCC 11170|Rep: Cyclic nucleotide-binding domain (CNMP-BD) protein - Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255) Length = 129 Score = 50.8 bits (116), Expect = 2e-05 Identities = 25/68 (36%), Positives = 36/68 (52%) Frame = +2 Query: 245 GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASV 424 G V R+GD D Y++E+G+ D++V D E V+ T FGE+AL+ PR A+ Sbjct: 20 GAVVFREGDAADGVYLVESGLVDMIVRRPDGSEAVIGTVGAGEVFGEMALIDGHPRMATA 79 Query: 425 RAQTAGAL 448 R L Sbjct: 80 RVAMEATL 87 >UniRef50_Q10V66 Cluster: Cyclic nucleotide-binding protein; n=2; Oscillatoriales|Rep: Cyclic nucleotide-binding protein - Trichodesmium erythraeum (strain IMS101) Length = 454 Score = 50.8 bits (116), Expect = 2e-05 Identities = 24/91 (26%), Positives = 49/91 (53%) Frame = +2 Query: 152 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 331 E + + +F+ + +++++ A+ + P EY+IR+G+ G+ Y I+ G+ V Sbjct: 323 EVIEKVPIFQGSTSHFVEEIVIALKPEIVPPNEYIIREGNLGNEMYFIKRGLVQVF---S 379 Query: 332 DRVEKVVHTYEGSGSFGELALMYNMPRAASV 424 ++ + T E FGE++L+Y R AS+ Sbjct: 380 EKTGSIYRTMEAGTFFGEISLVYEKRRTASI 410 >UniRef50_A5UY70 Cluster: Cyclic nucleotide-binding protein; n=3; Chloroflexaceae|Rep: Cyclic nucleotide-binding protein - Roseiflexus sp. RS-1 Length = 388 Score = 50.8 bits (116), Expect = 2e-05 Identities = 25/66 (37%), Positives = 34/66 (51%) Frame = +2 Query: 242 PGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAAS 421 PG +I QG DNFY+I G +V + D E +V+ FGE+ L++ R A Sbjct: 277 PGAVIIEQGSPADNFYIITRGDVEVFIEHPDGGEIIVNHLSTGSYFGEIGLLHQGRRTAG 336 Query: 422 VRAQTA 439 VRA A Sbjct: 337 VRASFA 342 >UniRef50_Q125U4 Cluster: Transcriptional regulator, Crp/Fnr family; n=3; Burkholderiales|Rep: Transcriptional regulator, Crp/Fnr family - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 225 Score = 50.4 bits (115), Expect = 2e-05 Identities = 33/112 (29%), Positives = 54/112 (48%) Frame = +2 Query: 152 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 331 E +R + LF L A Q + V +A+ ++R + GE ++ QG + +I G V+ T Sbjct: 9 ELIRRVPLFSMLTASQAESVANAVVKRRFKRGEAIVEQGKKSNALSIILTGRARVITTDT 68 Query: 332 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWGHGPPHVSFAXC 487 E ++ T GE++L+ N P +A+V A+ G P FA C Sbjct: 69 RGREVILATMHPGDYVGEMSLIDNEPHSATVCAEVQTDALILGQP--EFARC 118 >UniRef50_A0GWU5 Cluster: Stage II sporulation E; n=2; Chloroflexus|Rep: Stage II sporulation E - Chloroflexus aggregans DSM 9485 Length = 563 Score = 50.4 bits (115), Expect = 2e-05 Identities = 27/95 (28%), Positives = 51/95 (53%) Frame = +2 Query: 146 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 325 + + +R + LF+++ + + + E R PGE + QGD G YV+ +G +V +T Sbjct: 139 MLDRLRSLPLFQAVPEAVLSALAPRLAECRLAPGEVLFHQGDTGHECYVVLSGAVEV-IT 197 Query: 326 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 430 + E + + GE++L+ + PR+A+VRA Sbjct: 198 FVNGAELRLEVFHSGQIIGEMSLIDHSPRSATVRA 232 >UniRef50_A0DBC7 Cluster: Chromosome undetermined scaffold_44, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_44, whole genome shotgun sequence - Paramecium tetraurelia Length = 495 Score = 50.4 bits (115), Expect = 2e-05 Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 6/102 (5%) Frame = +2 Query: 134 QRARLAEAVRGILLFRSLDAQQMQ---QVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG 304 Q +L E + I F L + Q + DA+ K E + +QGD GD FY++ G Sbjct: 38 QAIKLQELLSTIKYFAQLFQSKQQLIYDIADALQYKFVHQNEIIFKQGDQGDMFYIVLQG 97 Query: 305 VFDVLVT---GDDRVEKVVHTYEGSGSFGELALMYNMPRAAS 421 + + D V K V T GSFGELAL + R A+ Sbjct: 98 TVSIQINIPQEDVFVPKEVATITEGGSFGELALQSSQARTAT 139 >UniRef50_Q2ADG0 Cluster: Cyclic nucleotide-binding:Bacterial regulatory protein, Crp; n=1; Halothermothrix orenii H 168|Rep: Cyclic nucleotide-binding:Bacterial regulatory protein, Crp - Halothermothrix orenii H 168 Length = 219 Score = 50.0 bits (114), Expect = 3e-05 Identities = 25/89 (28%), Positives = 46/89 (51%) Frame = +2 Query: 161 RGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRV 340 R I LF L+ +Q+ + ++R + GE + +GD D FY++ G ++ D Sbjct: 7 RSIPLFSGLNDEQLDLLKSITNKRRYKAGEILFFEGDKPDAFYIVVEGEIQIIKVSYDGK 66 Query: 341 EKVVHTYEGSGSFGELALMYNMPRAASVR 427 EK++ FGE+A++ + R+A+ R Sbjct: 67 EKILEVMGPGDFFGEMAIIDSKGRSATAR 95 >UniRef50_Q1D5Q4 Cluster: Cyclic nucleotide-binding domain protein; n=1; Myxococcus xanthus DK 1622|Rep: Cyclic nucleotide-binding domain protein - Myxococcus xanthus (strain DK 1622) Length = 715 Score = 50.0 bits (114), Expect = 3e-05 Identities = 32/93 (34%), Positives = 46/93 (49%) Frame = +2 Query: 152 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 331 +A+ I LF L ++ + +R P E +I QG GD FYVI G V T + Sbjct: 442 DALPTIPLFSDLPRDAFIELFERCPLRRFGPDERIIDQGSHGDAFYVICEGAVRVFRTEE 501 Query: 332 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 430 + + + T EG FGE+AL+ R ASV + Sbjct: 502 GQRQDIA-TLEGGTFFGEMALLSGAARTASVES 533 Score = 35.1 bits (77), Expect = 0.92 Identities = 24/86 (27%), Positives = 39/86 (45%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 352 LFR + + +++ + E +IR GD D YV+ +G +V G + Sbjct: 580 LFRLFGRKDRRALVERFRSRDVERDTVIIRDGDPTDGLYVVLSGEVEVRKDG----HLLT 635 Query: 353 HTYEGSGSFGELALMYNMPRAASVRA 430 EG FGE++L+ P A+V A Sbjct: 636 QLREGD-VFGEISLLQKTPATATVTA 660 >UniRef50_Q2LPZ1 Cluster: Cyclic nucleotide-binding domain protein; n=1; Syntrophus aciditrophicus SB|Rep: Cyclic nucleotide-binding domain protein - Syntrophus aciditrophicus (strain SB) Length = 229 Score = 49.6 bits (113), Expect = 4e-05 Identities = 22/82 (26%), Positives = 42/82 (51%) Frame = +2 Query: 143 RLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV 322 ++ E + I LF L QQ+ ++ ++ + G+ + +GD+G FY++ +G V Sbjct: 3 KVLEIIGSIPLFNGLSEQQLGEIRGIARDRFYDKGKEIFAEGDEGGGFYIVASGQVKVFK 62 Query: 323 TGDDRVEKVVHTYEGSGSFGEL 388 + E ++H Y SFGE+ Sbjct: 63 LSPEGKEHILHIYGPGHSFGEV 84 >UniRef50_P74608 Cluster: Slr1575 protein; n=1; Synechocystis sp. PCC 6803|Rep: Slr1575 protein - Synechocystis sp. (strain PCC 6803) Length = 479 Score = 49.6 bits (113), Expect = 4e-05 Identities = 27/102 (26%), Positives = 57/102 (55%) Frame = +2 Query: 146 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 325 L++ ++ F L+ +++Q+++ + + E + R+ D D FY++ +G+ +V Sbjct: 314 LSQVLKSSDYFSGLNELEIRQLVEIGQLQSLQSEEVLFRERDPADGFYIVISGLVEVYT- 372 Query: 326 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 +++ +V+ + FGELALM +PR ASV+A+ L+ Sbjct: 373 --EKLGRVLASLGPGSFFGELALMLGIPRTASVKAKEKSLLF 412 >UniRef50_Q08NQ8 Cluster: Protein phosphatase 1; n=2; Cystobacterineae|Rep: Protein phosphatase 1 - Stigmatella aurantiaca DW4/3-1 Length = 470 Score = 49.6 bits (113), Expect = 4e-05 Identities = 36/111 (32%), Positives = 56/111 (50%) Frame = +2 Query: 98 EGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDG 277 +GA A S+AQ +R+ EA+R I LFR L ++ VL + G ++ +G G Sbjct: 301 DGAVASEETSEAQ-SRM-EALRKIPLFRHLTYKEQTAVLSIATTRTFPAGREIVVEGQPG 358 Query: 278 DNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 430 + +V+ G + G + E G FGE+ L+ N PR+A+VRA Sbjct: 359 EELFVVIRGRVVIEKNGVEIAE-----LRAGGHFGEMGLIDNAPRSATVRA 404 >UniRef50_Q2VWB6 Cluster: CAMP-dependent protein kinase A regulatory subunit; n=2; Giardia intestinalis|Rep: CAMP-dependent protein kinase A regulatory subunit - Giardia lamblia (Giardia intestinalis) Length = 460 Score = 49.6 bits (113), Expect = 4e-05 Identities = 30/101 (29%), Positives = 55/101 (54%) Frame = +2 Query: 128 DAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGV 307 +A+ R +R + + + L ++ + A + G+ ++ QGD+G+ FY IE+G Sbjct: 335 EAEIQRYIGFLRHVEVLKQLRENELFALAQACTPEYYIDGQDIVTQGDEGNTFYFIEDGR 394 Query: 308 FDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 430 DV+V+ D +V ++ + FGE AL+ N PR A+ R+ Sbjct: 395 VDVIVS-DHKVAEL----SSNSYFGEAALLNNAPRNATCRS 430 >UniRef50_Q23WN2 Cluster: Cyclic nucleotide-binding domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 1010 Score = 49.6 bits (113), Expect = 4e-05 Identities = 26/69 (37%), Positives = 39/69 (56%) Frame = +2 Query: 221 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 400 M +R G+ V QGD G FY+I G+ + + + +KV G SFGELAL+ Sbjct: 61 MTYERFNSGDMVFSQGDRGSKFYIILEGLVGIYIKIKNEQKKVKELSRGE-SFGELALIN 119 Query: 401 NMPRAASVR 427 + PR+AS++ Sbjct: 120 DAPRSASIK 128 >UniRef50_O76977 Cluster: Hyperpolarization-activated (Ih) channel; n=5; Eumetazoa|Rep: Hyperpolarization-activated (Ih) channel - Strongylocentrotus purpuratus (Purple sea urchin) Length = 767 Score = 49.6 bits (113), Expect = 4e-05 Identities = 30/117 (25%), Positives = 57/117 (48%), Gaps = 1/117 (0%) Frame = +2 Query: 122 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 301 + D + V + F D+ + +V+ + + +P +YVI++G GD + I+ Sbjct: 528 RQDVANYNCRDLVASVPFFVGADSNFVTRVVTLLEFEVFQPADYVIQEGTFGDRMFFIQQ 587 Query: 302 GVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWGHGPPH 469 G+ D++++ + V+ T GS FGE+ L+ R ASV+ +T L+ H Sbjct: 588 GIVDIIMS-----DGVIATSLSDGSYFGEICLLTRERRVASVKCETYCTLFSLSVQH 639 >UniRef50_UPI000038CAE8 Cluster: COG1252: NADH dehydrogenase, FAD-containing subunit; n=1; Nostoc punctiforme PCC 73102|Rep: COG1252: NADH dehydrogenase, FAD-containing subunit - Nostoc punctiforme PCC 73102 Length = 980 Score = 49.2 bits (112), Expect = 5e-05 Identities = 28/86 (32%), Positives = 47/86 (54%) Frame = +2 Query: 182 SLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTY 361 S+ Q+ Q + A F+ G+ +++QGD G Y+I NG +VL + E ++ T Sbjct: 421 SMKVQEKQSLKKAYFQA----GQVIVKQGDIGRCLYLIRNGEVEVLQEMSNG-ETIIQTI 475 Query: 362 EGSGSFGELALMYNMPRAASVRAQTA 439 FGE +++ N P A+VRA+T+ Sbjct: 476 GSGEHFGETSVIENSPHIATVRAKTS 501 >UniRef50_Q98GM7 Cluster: Mlr3256 protein; n=2; Alphaproteobacteria|Rep: Mlr3256 protein - Rhizobium loti (Mesorhizobium loti) Length = 151 Score = 49.2 bits (112), Expect = 5e-05 Identities = 27/62 (43%), Positives = 36/62 (58%) Frame = +2 Query: 245 GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASV 424 G+ + RQGD+GD YVI +G D+LV D KV S GE+A++ N R A+V Sbjct: 39 GQILFRQGDEGDAAYVILSGKADILVESDSGPIKVAELVPNS-IVGEIAILCNSSRTATV 97 Query: 425 RA 430 RA Sbjct: 98 RA 99 >UniRef50_Q8XR93 Cluster: Probable transcription regulator protein; n=6; Ralstonia|Rep: Probable transcription regulator protein - Ralstonia solanacearum (Pseudomonas solanacearum) Length = 225 Score = 49.2 bits (112), Expect = 5e-05 Identities = 29/103 (28%), Positives = 45/103 (43%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 352 LF LDA+ + + + R ++V +GD D FYV+ G +++ G KV+ Sbjct: 16 LFEGLDAEDLATLARDSHQIRLARHDFVFHRGDCADGFYVVAVGTIKLVLPGAHGHNKVI 75 Query: 353 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWGHGPPHVSFA 481 + FGE + N P AA +A L G P + A Sbjct: 76 EFFGPGEYFGEPFMFLNQPHAADAQALEDSLLIRIGKPTIDAA 118 >UniRef50_Q23EB7 Cluster: Cyclic nucleotide-binding domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 1079 Score = 49.2 bits (112), Expect = 5e-05 Identities = 25/103 (24%), Positives = 53/103 (51%), Gaps = 2/103 (1%) Frame = +2 Query: 149 AEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTG 328 ++ ++ +F+ Q + +++ M E PGE + +GD D+ Y+I NG ++ ++G Sbjct: 504 SQIIKKFDIFKCFSQQTINKLVFLMKEIIVSPGETIFLEGDLDDSVYLILNGQIEIFISG 563 Query: 329 --DDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 ++ K++ + FGE+A PR+AS ++ L+ Sbjct: 564 NQNNSQTKILKDLSNNQIFGEIAFFCQKPRSASAKSIVLSTLY 606 >UniRef50_P63401 Cluster: Uncharacterized ABC transporter ATP-binding protein Rv2564/MT2640; n=14; Mycobacterium tuberculosis complex|Rep: Uncharacterized ABC transporter ATP-binding protein Rv2564/MT2640 - Mycobacterium tuberculosis Length = 330 Score = 49.2 bits (112), Expect = 5e-05 Identities = 23/71 (32%), Positives = 41/71 (57%) Frame = +2 Query: 245 GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASV 424 GE + Q GD YV+ G F+++ D E++V T FGE+ +++++PR+A+V Sbjct: 234 GEVLFEQSTMGDLIYVVSEGEFEIVRELADGGEELVKTAAPGDYFGEIGVLFHLPRSATV 293 Query: 425 RAQTAGALWGH 457 RA++ G+ Sbjct: 294 RARSDATAVGY 304 >UniRef50_Q46TY3 Cluster: Cyclic nucleotide-binding; n=2; Cupriavidus necator|Rep: Cyclic nucleotide-binding - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 260 Score = 48.8 bits (111), Expect = 7e-05 Identities = 34/123 (27%), Positives = 49/123 (39%), Gaps = 2/123 (1%) Frame = +2 Query: 101 GAPAVFPKSDA--QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDD 274 G P P +A RA A ++ F L + +LD + GE + +GD Sbjct: 16 GIPRGTPGGNAAPSRAEAAATLQASAWFSQLPGPLREALLDDGTWRHLAAGEALFARGDA 75 Query: 275 GDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWG 454 D Y + +G V G+ ++ E FGE+ L +PR RA A LW Sbjct: 76 FDGLYCVASGTMQVDAAGESGKAALLGLLEAGAWFGEICLFDGLPRTHDARAVHAARLW- 134 Query: 455 HGP 463 H P Sbjct: 135 HVP 137 >UniRef50_A3YU60 Cluster: Putative glutaminase; n=1; Synechococcus sp. WH 5701|Rep: Putative glutaminase - Synechococcus sp. WH 5701 Length = 620 Score = 48.8 bits (111), Expect = 7e-05 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 4/93 (4%) Frame = +2 Query: 185 LDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT--GDD--RVEKVV 352 L Q + D M + GE+V+++GD G +++ G F + V G D + Sbjct: 482 LQPTHRQTLADLMQCRNFAKGEHVVKKGDPGHELFLVREGRFTITVELRGSDGQTYASRL 541 Query: 353 HTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 T+E FGE+A + PR A+V A G+ W Sbjct: 542 ATFEPGMCFGEIAFLSGTPRTANVTADLDGSCW 574 >UniRef50_A0YHV0 Cluster: Putative uncharacterized protein; n=1; marine gamma proteobacterium HTCC2143|Rep: Putative uncharacterized protein - marine gamma proteobacterium HTCC2143 Length = 159 Score = 48.8 bits (111), Expect = 7e-05 Identities = 23/64 (35%), Positives = 39/64 (60%) Frame = +2 Query: 245 GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASV 424 GE+ Q D GD+ +++E G ++ T + ++ V+ T FGE+AL+ PR+A+V Sbjct: 39 GEFFFHQNDKGDSLFLLEKGSAEIFKTFNG-IDYVLRTVNNGDCFGEMALIDFTPRSATV 97 Query: 425 RAQT 436 RA+T Sbjct: 98 RAKT 101 >UniRef50_A0DG99 Cluster: Chromosome undetermined scaffold_5, whole genome shotgun sequence; n=4; Oligohymenophorea|Rep: Chromosome undetermined scaffold_5, whole genome shotgun sequence - Paramecium tetraurelia Length = 869 Score = 48.8 bits (111), Expect = 7e-05 Identities = 31/99 (31%), Positives = 53/99 (53%), Gaps = 1/99 (1%) Frame = +2 Query: 143 RLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV 322 R + + I +F L + ++ +LD++ + PG+ VI++G GD FY+IE+G+ V Sbjct: 606 RRLDLLSTIDIFEHLTLKNVRWLLDSVTSEEFFPGQDVIKEGTAGDRFYIIESGL--ARV 663 Query: 323 TGDDRVEKVVHTYEGSGSFGELALMYNM-PRAASVRAQT 436 + ++ Y+ FGE A++ N R ASV A T Sbjct: 664 YSKQKGQEFERYYQVGDYFGESAVLSNEGRRGASVEAVT 702 >UniRef50_Q3AAI0 Cluster: CBS/cyclic nucleotide-binding domain protein; n=1; Carboxydothermus hydrogenoformans Z-2901|Rep: CBS/cyclic nucleotide-binding domain protein - Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008) Length = 631 Score = 48.4 bits (110), Expect = 9e-05 Identities = 27/110 (24%), Positives = 55/110 (50%), Gaps = 1/110 (0%) Frame = +2 Query: 146 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDN-FYVIENGVFDVLV 322 + + + I F L ++++ +++ + +PGEY+ R+ + N +++ NG+ +++V Sbjct: 1 MPQTLSHIYPFSLLPENLLEELSNSLTSRNYQPGEYIFREKEPARNGLFLVFNGILEIVV 60 Query: 323 TGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWGHGPPHV 472 T + + V+ FGE L P A +RA T AL G P ++ Sbjct: 61 TSERGQDLVIALRRPGEFFGETVLFSGEPYPAGIRAATE-ALIGFIPKNI 109 >UniRef50_Q0VQV6 Cluster: Cyclic nucleotide-binding domain protein; n=1; Alcanivorax borkumensis SK2|Rep: Cyclic nucleotide-binding domain protein - Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) Length = 357 Score = 48.4 bits (110), Expect = 9e-05 Identities = 30/93 (32%), Positives = 45/93 (48%), Gaps = 1/93 (1%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT-GDDRVEKV 349 LF + + + + R + GE +IRQG+ D Y+++ GV +V + G+ V Sbjct: 148 LFHRVPPSNILGIFSRLKANRHKEGERIIRQGEAADCCYILKEGVCEVSINIGEGEPTSV 207 Query: 350 VHTYEGSGSFGELALMYNMPRAASVRAQTAGAL 448 EG FGE AL+ PR A+V T G L Sbjct: 208 AMLEEGEW-FGEEALLSGKPRNATVSMATDGVL 239 >UniRef50_A3YU63 Cluster: Possible mechanosensitive ion channel; n=1; Synechococcus sp. WH 5701|Rep: Possible mechanosensitive ion channel - Synechococcus sp. WH 5701 Length = 492 Score = 48.4 bits (110), Expect = 9e-05 Identities = 26/86 (30%), Positives = 46/86 (53%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 352 LF L ++M Q+ R PGE V+R+G+ GD+ + + G+ +VL ++ V Sbjct: 340 LFGDLSEEEMLQLARNTRCLRFAPGEVVVREGNRGDSLFQVVQGMVEVLKNQEEEEPFQV 399 Query: 353 HTYEGSGSFGELALMYNMPRAASVRA 430 + FGE++++ R+A+VRA Sbjct: 400 ACLKPGDVFGEMSMLAGSQRSATVRA 425 >UniRef50_Q2SDD5 Cluster: CAMP-binding protein-catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; n=3; Gammaproteobacteria|Rep: CAMP-binding protein-catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase - Hahella chejuensis (strain KCTC 2396) Length = 216 Score = 48.0 bits (109), Expect = 1e-04 Identities = 28/88 (31%), Positives = 45/88 (51%) Frame = +2 Query: 167 ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEK 346 I LF DA+Q+Q + + + VI +GD D+ Y+I +G V + ++ E Sbjct: 7 IPLFSGFDAEQLQHLEKHAVFRCFQKNSIVITEGDHSDSLYIIVSGRVRVFCSDENGKEV 66 Query: 347 VVHTYEGSGSFGELALMYNMPRAASVRA 430 ++ + FGELAL + R+ASV A Sbjct: 67 TLNDLKAGEYFGELALFDDKERSASVMA 94 >UniRef50_Q3W7N0 Cluster: Cyclic nucleotide-binding domain:Peptidase M50 precursor; n=1; Frankia sp. EAN1pec|Rep: Cyclic nucleotide-binding domain:Peptidase M50 precursor - Frankia sp. EAN1pec Length = 968 Score = 48.0 bits (109), Expect = 1e-04 Identities = 35/124 (28%), Positives = 58/124 (46%), Gaps = 2/124 (1%) Frame = +2 Query: 86 DDSDEGAPAVFPKSDAQ-RARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIR 262 D SD AP + +++ RA + G LF L + +L + + GE V+ Sbjct: 594 DFSDRLAPLLARRAENDTRADERAELEGFALFDGLRTRDKDTLLAHLRARSCVDGEVVVA 653 Query: 263 QGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTA 439 +GD G FY++ +G + T D + + G+G FGE AL+++ P AA+ + Sbjct: 654 EGDPGSAFYLVRSGAVALAQTCVDGPPRTL----GAGEFFGESALLHDEPHAATATSVGE 709 Query: 440 GALW 451 LW Sbjct: 710 TRLW 713 >UniRef50_A6G0I3 Cluster: Putative uncharacterized protein; n=1; Plesiocystis pacifica SIR-1|Rep: Putative uncharacterized protein - Plesiocystis pacifica SIR-1 Length = 428 Score = 48.0 bits (109), Expect = 1e-04 Identities = 24/64 (37%), Positives = 37/64 (57%) Frame = +2 Query: 239 EPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAA 418 EPGE +I++G+ + YVI +G +V GDD E+ + + FGE A+ + R A Sbjct: 326 EPGEVIIQEGEVAETAYVIIDGSCEVSRVGDDGGEQRLRVMDAGEVFGETAIFAGVRRTA 385 Query: 419 SVRA 430 +VRA Sbjct: 386 TVRA 389 >UniRef50_Q22R60 Cluster: Cyclic nucleotide-binding domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 863 Score = 48.0 bits (109), Expect = 1e-04 Identities = 24/61 (39%), Positives = 35/61 (57%) Frame = +2 Query: 254 VIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQ 433 VI G+ GD FY+I G+ ++ V V + SFGELAL+ + PR A+++AQ Sbjct: 86 VIVHGERGDKFYIILQGICEIYVPNSQGQFVKVGELKAGQSFGELALINDSPRRATIKAQ 145 Query: 434 T 436 T Sbjct: 146 T 146 >UniRef50_A7SFW1 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 968 Score = 48.0 bits (109), Expect = 1e-04 Identities = 26/68 (38%), Positives = 41/68 (60%) Frame = +2 Query: 221 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 400 + E G + QGD+GD++Y+I G +V+V G V + +HT++ FG L+L+ Sbjct: 330 VLESCEHKGTVLFNQGDEGDSWYIILKGSVNVVVLGKGIVCQ-LHTWD---DFGRLSLVN 385 Query: 401 NMPRAASV 424 N PRAAS+ Sbjct: 386 NAPRAASI 393 Score = 35.9 bits (79), Expect = 0.53 Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 2/86 (2%) Frame = +2 Query: 170 LLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKV 349 L+F+ + ++Q+ + + EPG + RQ G N+Y I G ++ V+ ++E Sbjct: 13 LVFKKVHPHVVRQICFYAYYEDLEPGTVLYRQDAKGLNWYAILTGSVNICVSQTSKIEDA 72 Query: 350 VH-TYEGSGS-FGELALMYNMPRAAS 421 V G GS FGE +++ PR A+ Sbjct: 73 VTLCCLGPGSTFGE-SVLDGSPRTAT 97 >UniRef50_A3EYY6 Cluster: Tetrameric potassium-selective cyclic nucleotide gated channel; n=4; Eumetazoa|Rep: Tetrameric potassium-selective cyclic nucleotide gated channel - Strongylocentrotus purpuratus (Purple sea urchin) Length = 2238 Score = 48.0 bits (109), Expect = 1e-04 Identities = 30/91 (32%), Positives = 47/91 (51%), Gaps = 1/91 (1%) Frame = +2 Query: 167 ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL-VTGDDRVE 343 + LFR D ++ + + P + ++RQGD GD Y I GV + L V RV Sbjct: 2097 VALFREADEAFLRALSLMLKPVLFMPNDLIVRQGDVGDEMYFICRGVVEELEVNSHSRVA 2156 Query: 344 KVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 +V+ T E ++ L+Y++PR S RA+T Sbjct: 2157 RVLETGE---FLDDINLLYDVPRRTSYRART 2184 Score = 45.6 bits (103), Expect = 7e-04 Identities = 23/62 (37%), Positives = 38/62 (61%) Frame = +2 Query: 248 EYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVR 427 EY++R+ D G + I G+ +V V+ D + V T + FGE++L+++ PR AS+R Sbjct: 1489 EYIVRKHDFGKEMFFIHRGLVEV-VSEDGSI--VFDTMQAGRFFGEISLVFSCPRTASIR 1545 Query: 428 AQ 433 AQ Sbjct: 1546 AQ 1547 Score = 39.9 bits (89), Expect = 0.032 Identities = 27/94 (28%), Positives = 45/94 (47%), Gaps = 1/94 (1%) Frame = +2 Query: 152 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 331 E + + LF+ D+ ++ + + PG+ ++ QGD G Y I G +VL Sbjct: 908 ETLSKVPLFKECDSNFLRMLALKLHVFIFMPGDVIVYQGDMGREMYFIRRGTCEVLSKDG 967 Query: 332 DRVEKVVHTYEGSGS-FGELALMYNMPRAASVRA 430 + V + G G FGE+ L++ R A+VRA Sbjct: 968 NHVMSNI----GPGQYFGEVGLIFGDYRTATVRA 997 Score = 34.3 bits (75), Expect = 1.6 Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 5/75 (6%) Frame = +2 Query: 221 MFEKRSEPGEYVIRQGDDGDN-----FYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGE 385 M +P Y+ RQ G N Y I+ G +VL DD + G FGE Sbjct: 381 MLSLEIKPSLYLPRQKIAGRNEICHDMYFIQRGEIEVLSADDDDTP-IARLNHGK-LFGE 438 Query: 386 LALMYNMPRAASVRA 430 ++L+++MPR ++RA Sbjct: 439 VSLIFSMPRTNTIRA 453 >UniRef50_UPI00006CA698 Cluster: cation channel family protein; n=2; Tetrahymena thermophila SB210|Rep: cation channel family protein - Tetrahymena thermophila SB210 Length = 2774 Score = 47.6 bits (108), Expect = 2e-04 Identities = 23/93 (24%), Positives = 52/93 (55%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 337 V+ + +F A+ + ++L M+ + + ++V++ G+ +FY++ G +++ D+ Sbjct: 264 VQNVQIFNLGQAEFVAKMLKKMYPQVAVKDDFVLKMGESAQDFYILAKGRVEIV--NQDK 321 Query: 338 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 ++V+ E FGE+A++ N R V+AQT Sbjct: 322 -KQVIRVLEPGAYFGEVAILINQYRTCYVKAQT 353 Score = 37.1 bits (82), Expect = 0.23 Identities = 23/71 (32%), Positives = 38/71 (53%), Gaps = 2/71 (2%) Frame = +2 Query: 245 GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMP--RAA 418 GE+V ++GD Y IE GV + V ++ E+V+ G FG L + +P R Sbjct: 828 GEFVFQKGDLAQEIYFIEEGVVQI-VNNNNNNEEVLAEISQYGYFGGLEFINIVPSLRKI 886 Query: 419 SVRAQTAGALW 451 S++A+T +L+ Sbjct: 887 SIKAKTNTSLF 897 >UniRef50_Q6MJQ6 Cluster: Hyperpolarization-activated, cyclic nucleotide-gated K+; n=1; Bdellovibrio bacteriovorus|Rep: Hyperpolarization-activated, cyclic nucleotide-gated K+ - Bdellovibrio bacteriovorus Length = 130 Score = 47.6 bits (108), Expect = 2e-04 Identities = 24/74 (32%), Positives = 45/74 (60%), Gaps = 1/74 (1%) Frame = +2 Query: 218 AMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKV-VHTYEGSGSFGELAL 394 A+ ++ +PG+++ +GD ++FY++E+GV + T D +++ + SFGE AL Sbjct: 6 AIVKETYKPGDFIFFEGDIENHFYIVESGVVSIF-TKDQMGKRIPICDIVDGESFGEFAL 64 Query: 395 MYNMPRAASVRAQT 436 + PR+AS +A T Sbjct: 65 ISKSPRSASAQAVT 78 >UniRef50_Q2S6T5 Cluster: CAMP-binding protein-catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; n=1; Hahella chejuensis KCTC 2396|Rep: CAMP-binding protein-catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase - Hahella chejuensis (strain KCTC 2396) Length = 360 Score = 47.6 bits (108), Expect = 2e-04 Identities = 31/93 (33%), Positives = 54/93 (58%), Gaps = 1/93 (1%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEK-RSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKV 349 LF +L +++V A FE+ + G+ +I +GD+GD FY++ +G V++ GD+ K Sbjct: 167 LFFNLPPANVEKVF-ARFERIEVKKGQVIIEEGDEGDYFYLLIDGSARVVIGGDE--SKP 223 Query: 350 VHTYEGSGSFGELALMYNMPRAASVRAQTAGAL 448 + +GS FGE AL+ + R+A++ G L Sbjct: 224 IRVSKGS-YFGEEALVSDTVRSATIIMSEDGVL 255 >UniRef50_Q2RK98 Cluster: Transcriptional regulator, Crp/Fnr family; n=2; Clostridia|Rep: Transcriptional regulator, Crp/Fnr family - Moorella thermoacetica (strain ATCC 39073) Length = 225 Score = 47.6 bits (108), Expect = 2e-04 Identities = 22/92 (23%), Positives = 43/92 (46%) Frame = +2 Query: 152 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 331 E +R + +F L+ +++Q + +R Y+ +G+ GD FY ++ G + + Sbjct: 6 EFLRQVPVFAGLEPEELQHIASLALLRRYRKNMYIFMEGEPGDAFYFVKKGAIKLFQVLE 65 Query: 332 DRVEKVVHTYEGSGSFGELALMYNMPRAASVR 427 D EK++H F E+ L P A+ + Sbjct: 66 DGREKILHFVREGEIFAEVLLFEGGPYPATAQ 97 >UniRef50_Q2LV90 Cluster: CAMP-dependent transcriptional regulator; n=2; Syntrophus aciditrophicus SB|Rep: CAMP-dependent transcriptional regulator - Syntrophus aciditrophicus (strain SB) Length = 249 Score = 47.6 bits (108), Expect = 2e-04 Identities = 25/100 (25%), Positives = 47/100 (47%) Frame = +2 Query: 152 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 331 + ++ I LF S + +++ + + + + GE + +GD G F++I NG+ + V+ Sbjct: 28 DLLKAIPLFESFNNSELRHLASLLKGQSLDKGEILFHKGDTGSAFFIIANGLIRISVSNK 87 Query: 332 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 E G FGE+AL+ R+A A L+ Sbjct: 88 AGDEVTFAHLRGGDFFGEMALLDEQTRSADATALEDSTLY 127 >UniRef50_A0LIE9 Cluster: Cyclic nucleotide-binding protein; n=1; Syntrophobacter fumaroxidans MPOB|Rep: Cyclic nucleotide-binding protein - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 308 Score = 47.6 bits (108), Expect = 2e-04 Identities = 28/86 (32%), Positives = 44/86 (51%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 352 LFR + ++ ++ + + +VIRQGD D FYVI +G V + +E+ + Sbjct: 17 LFRDIPKDRLAEIARSAQNRIVPQHGFVIRQGDAADVFYVIASGRVRVTKKNERGMEREL 76 Query: 353 HTYEGSGSFGELALMYNMPRAASVRA 430 +FGE+AL+ PRAA V A Sbjct: 77 GFLGPGDNFGEIALLTGEPRAADVVA 102 >UniRef50_Q1NMR4 Cluster: Cyclic nucleotide-binding; n=2; delta proteobacterium MLMS-1|Rep: Cyclic nucleotide-binding - delta proteobacterium MLMS-1 Length = 358 Score = 47.2 bits (107), Expect = 2e-04 Identities = 26/66 (39%), Positives = 36/66 (54%), Gaps = 1/66 (1%) Frame = +2 Query: 242 PGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF-GELALMYNMPRAA 418 PGE + +GD G + Y IE G ++ V D R V++T G+G G L + PR A Sbjct: 13 PGELLFNKGDPGGDLYFIEQGSLEIFVYQDGR--PVIYTEMGAGEIVGVLTCLTGEPRMA 70 Query: 419 SVRAQT 436 S RA+T Sbjct: 71 SARAKT 76 >UniRef50_Q1D9I5 Cluster: PBS lyase HEAT-like repeat/cyclic nucleotide-binding domain protein; n=2; Cystobacterineae|Rep: PBS lyase HEAT-like repeat/cyclic nucleotide-binding domain protein - Myxococcus xanthus (strain DK 1622) Length = 1034 Score = 47.2 bits (107), Expect = 2e-04 Identities = 27/92 (29%), Positives = 42/92 (45%) Frame = +2 Query: 155 AVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDD 334 A+ G+ +F D + + E GE + QGD GD YVI +G D G+ Sbjct: 866 ALEGVSVFSQCDVDDIAAIAAVAREASFRTGERIYAQGDPGDALYVIVDGAVDAFHDGEH 925 Query: 335 RVEKVVHTYEGSGSFGELALMYNMPRAASVRA 430 V ++G +FGE++L+ PR + A Sbjct: 926 -----VLRFQGKQAFGEVSLLDGAPRPTDMVA 952 >UniRef50_Q0LJ13 Cluster: Cyclic nucleotide-binding; n=2; Chloroflexi (class)|Rep: Cyclic nucleotide-binding - Herpetosiphon aurantiacus ATCC 23779 Length = 166 Score = 47.2 bits (107), Expect = 2e-04 Identities = 25/96 (26%), Positives = 51/96 (53%), Gaps = 5/96 (5%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV----- 322 +R + +F L+ ++ Q+ +++ G+ + R+ DGD+ YV+ +G ++ V Sbjct: 9 LRRVDIFAGLNDLELSQIAQLCKVAKAKKGQIIFREDSDGDDLYVVHDGAVEIQVQTRGS 68 Query: 323 TGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 430 G R+ + YEG +FGE+A++ R+A+ A Sbjct: 69 DGQHRLSTINTAYEGQ-AFGEIAMLGGGSRSATAVA 103 >UniRef50_Q0F2T2 Cluster: Glucose-6-phosphate 1-dehydrogenase; n=1; Mariprofundus ferrooxydans PV-1|Rep: Glucose-6-phosphate 1-dehydrogenase - Mariprofundus ferrooxydans PV-1 Length = 665 Score = 47.2 bits (107), Expect = 2e-04 Identities = 29/69 (42%), Positives = 37/69 (53%) Frame = +2 Query: 245 GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASV 424 G+ + R G +G Y+IE G DV+ D VV T G FGEL+L+ R ASV Sbjct: 558 GDEIARLGTEGRELYIIEMGSVDVI----DPEGNVVTTLSGGQVFGELSLLVTKERRASV 613 Query: 425 RAQTAGALW 451 RA T AL+ Sbjct: 614 RAVTYCALY 622 >UniRef50_Q09BB2 Cluster: Cyclic nucleotide-binding:Bacterial regulatory protein, Crp; n=2; Stigmatella aurantiaca DW4/3-1|Rep: Cyclic nucleotide-binding:Bacterial regulatory protein, Crp - Stigmatella aurantiaca DW4/3-1 Length = 226 Score = 47.2 bits (107), Expect = 2e-04 Identities = 26/90 (28%), Positives = 48/90 (53%), Gaps = 1/90 (1%) Frame = +2 Query: 167 ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEK 346 I LF +L A+ ++ + + + G+ + +QGD+G + Y++ G + + + E Sbjct: 10 IPLFENLQAEDLEHLSTLLHTRHCAKGDVIFQQGDEGADLYIVRAGQVAIRLHSPEGKE- 68 Query: 347 VVHTYEGSGS-FGELALMYNMPRAASVRAQ 433 V+ T GSG FGEL+L+ PR+ A+ Sbjct: 69 VILTLLGSGEVFGELSLLDGEPRSTHAVAR 98 >UniRef50_Q05VE2 Cluster: Possible mechanosensitive ion channel; n=2; Synechococcus|Rep: Possible mechanosensitive ion channel - Synechococcus sp. RS9916 Length = 494 Score = 47.2 bits (107), Expect = 2e-04 Identities = 35/121 (28%), Positives = 54/121 (44%), Gaps = 5/121 (4%) Frame = +2 Query: 77 PEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYV 256 P D E PA P S + + +F L QQ+ + + PGE V Sbjct: 303 PVRDIRTEPVPARLPSSAVNPGQKQRLLACTDIFGHLSDQQLGALAANASCQSFAPGETV 362 Query: 257 IRQGDDGDNFYVIENGVFDVL-VTGDDRVEKV----VHTYEGSGSFGELALMYNMPRAAS 421 +RQG+ GD+ +++ +G DV +G + + V + S FGE+AL R+AS Sbjct: 363 VRQGERGDSLFLVVSGSLDVFQASGTNPARSLPGQQVASLHSSDIFGEMALCTGEARSAS 422 Query: 422 V 424 V Sbjct: 423 V 423 >UniRef50_Q7K3Z6 Cluster: GH01501p; n=4; Diptera|Rep: GH01501p - Drosophila melanogaster (Fruit fly) Length = 861 Score = 47.2 bits (107), Expect = 2e-04 Identities = 23/68 (33%), Positives = 41/68 (60%) Frame = +2 Query: 221 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 400 +FE ++ G + QGD+G ++Y++ G DV++ G + V T + FG+LAL+ Sbjct: 224 VFEAHAQAGTILFNQGDEGRSWYILLKGSVDVVIHG----KGTVATLKTGDDFGKLALIN 279 Query: 401 NMPRAASV 424 + PRAA++ Sbjct: 280 DAPRAATI 287 >UniRef50_Q131K0 Cluster: Cyclic nucleotide-binding precursor; n=1; Rhodopseudomonas palustris BisB5|Rep: Cyclic nucleotide-binding precursor - Rhodopseudomonas palustris (strain BisB5) Length = 367 Score = 46.8 bits (106), Expect = 3e-04 Identities = 34/102 (33%), Positives = 49/102 (48%) Frame = +2 Query: 143 RLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV 322 R E V + FR L A + ++ + + G V+R+G+ GD Y I +G V V Sbjct: 235 RTWELVISVPFFRDLGAAAVADIVRLLQARDVNAGTVVVREGEPGDAMYFIVSGEATVRV 294 Query: 323 TGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGAL 448 K V GS FGE+AL++N PR+A+V A L Sbjct: 295 A-----PKPVVLGPGS-FFGEMALLFNTPRSATVVATQPSVL 330 >UniRef50_Q5CD46 Cluster: PKA regulatory subunit homologous protein; n=6; Myxococcales|Rep: PKA regulatory subunit homologous protein - Myxococcus xanthus Length = 405 Score = 46.8 bits (106), Expect = 3e-04 Identities = 30/108 (27%), Positives = 51/108 (47%), Gaps = 1/108 (0%) Frame = +2 Query: 128 DAQRARLAE-AVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG 304 +A RA +AE G+ + + + +L+ + + PG+ V+ +G G + + + G Sbjct: 117 EATRAHVAEDGATGLPILSQVSRETFVALLEVLQVRAFFPGQTVVEEGTPGASMFALVEG 176 Query: 305 VFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGAL 448 DV+ +D + V T FGELAL+ PR A+V A L Sbjct: 177 RADVVRALEDGQRRSVGTVTPGDFFGELALISEGPRLATVVATERAVL 224 Score = 42.7 bits (96), Expect = 0.005 Identities = 34/106 (32%), Positives = 48/106 (45%), Gaps = 2/106 (1%) Frame = +2 Query: 137 RARLAE-AVRGILLFRSLDAQQMQQVLDAMFEKRS-EPGEYVIRQGDDGDNFYVIENGVF 310 R R+ E +R LF L Q V FE RS GE ++ QG GD FYV+ G Sbjct: 251 RRRMVENLLRSNPLFNQLSPAQKAAV-SRDFELRSFAAGEALMTQGQPGDAFYVLLRGRC 309 Query: 311 DVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGAL 448 + + FGE++L+ + P +A+VRA AG + Sbjct: 310 TPWLEQPHGRRVALSALREGDVFGEISLLLDKPVSATVRADVAGVV 355 >UniRef50_A0YM45 Cluster: Sulfate transporter family protein; n=1; Lyngbya sp. PCC 8106|Rep: Sulfate transporter family protein - Lyngbya sp. PCC 8106 Length = 759 Score = 46.8 bits (106), Expect = 3e-04 Identities = 26/88 (29%), Positives = 40/88 (45%) Frame = +2 Query: 188 DAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEG 367 D+QQ+ ++ + + P E++ R GD D Y +E G V+ K V TY Sbjct: 627 DSQQVIMLMKYLKLLQISPDEFIFRTGDLADGLYFVETGQVSVIFELPTGQMKRVQTYYS 686 Query: 368 SGSFGELALMYNMPRAASVRAQTAGALW 451 GE+ N+PR AS+ A L+ Sbjct: 687 GTILGEIGHYMNVPRTASIIADQPSRLY 714 >UniRef50_Q4D6P2 Cluster: Regulatory subunit of protein kinase a-like protein, putative; n=2; Trypanosoma cruzi|Rep: Regulatory subunit of protein kinase a-like protein, putative - Trypanosoma cruzi Length = 558 Score = 46.8 bits (106), Expect = 3e-04 Identities = 26/101 (25%), Positives = 48/101 (47%) Frame = +2 Query: 128 DAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGV 307 + +R R + + L AQ+ ++ +A+ E + G+ +IR G+ D ++I G Sbjct: 385 EEKRQRYFSFLENAPFIKDLPAQERLKIAEALKEDKYTEGDKIIRYGEKVDWLHIIVEGT 444 Query: 308 FDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 430 DV+ ++ E+ V T FG+L +Y+ A V A Sbjct: 445 ADVIGRNEEGEEEYVVTKNAGECFGDLEFLYHHETVADVVA 485 Score = 41.5 bits (93), Expect = 0.011 Identities = 32/130 (24%), Positives = 55/130 (42%) Frame = +2 Query: 47 RKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMF 226 R + A + EE S E A KS + + + + LF LD +++ ++ M Sbjct: 237 RLGISARSIGAEEMMSTEFPTAA--KSSEAASFIMKVLEKHFLFSFLDDKELHKLAMVMN 294 Query: 227 EKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNM 406 + G V+ +G+ FY+I +G + + DD + + FGEL L+Y Sbjct: 295 TEDFPEGIKVLVKGETNSKFYIILDGSATITMFEDDPDRIETESLQKGSVFGELGLLYET 354 Query: 407 PRAASVRAQT 436 SV + T Sbjct: 355 QSEVSVESTT 364 >UniRef50_Q10898 Cluster: Uncharacterized protein Rv0104/MT0113; n=8; Mycobacterium tuberculosis complex|Rep: Uncharacterized protein Rv0104/MT0113 - Mycobacterium tuberculosis Length = 504 Score = 46.8 bits (106), Expect = 3e-04 Identities = 27/69 (39%), Positives = 36/69 (52%) Frame = +2 Query: 245 GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASV 424 G + RQG+ D+F+VIE+G + LV G KV+ FGE L+ M R A+V Sbjct: 401 GYTLFRQGERADHFFVIESGELEALVDG-----KVILRLGAGDHFGEACLLGGMRRIATV 455 Query: 425 RAQTAGALW 451 RA LW Sbjct: 456 RACEPSVLW 464 >UniRef50_UPI00006CA699 Cluster: cyclic nucleotide-binding domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 2731 Score = 46.4 bits (105), Expect = 4e-04 Identities = 29/96 (30%), Positives = 51/96 (53%), Gaps = 1/96 (1%) Frame = +2 Query: 152 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 331 E + + +F Q + +++ + K + +Y+I+ G+ + FY+I G ++L G Sbjct: 232 ELISNVQIFNLGSPQFVLKMIKKLHPKVAVKDDYIIKIGEIAEEFYIISKGKVEML--GG 289 Query: 332 DRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQT 436 D+ K V+ SGS FGE+ ++ N R VRAQT Sbjct: 290 DK--KTVNRILESGSYFGEVGILLNQYRTCYVRAQT 323 Score = 46.0 bits (104), Expect = 5e-04 Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 3/79 (3%) Frame = +2 Query: 224 FEKRSEP-GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 400 FEK P GE+V ++GD Y IE G+ ++ DD E+++ + FG L + Sbjct: 692 FEKILVPRGEFVFQKGDLAQEMYFIEEGIIQIVKFNDDLKEEILGEIYKNSYFGGLEFIN 751 Query: 401 NMP--RAASVRAQTAGALW 451 +P R SVRA+T L+ Sbjct: 752 KVPTLRKVSVRAKTNACLY 770 >UniRef50_UPI00006A1C4D Cluster: Uncharacterized protein C20orf152.; n=2; Xenopus tropicalis|Rep: Uncharacterized protein C20orf152. - Xenopus tropicalis Length = 436 Score = 46.4 bits (105), Expect = 4e-04 Identities = 29/91 (31%), Positives = 51/91 (56%), Gaps = 4/91 (4%) Frame = +2 Query: 164 GILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL--VTGDDR 337 GIL FR +Q + ++ +R G ++R+G GD+FY + +GV V V G Sbjct: 30 GILSFRRYSSQMQLMLARVVYYRRFGRGRVIVRKGHRGDSFYFVFSGVIAVTQDVDGSSA 89 Query: 338 V--EKVVHTYEGSGSFGELALMYNMPRAASV 424 + + + ++G+ SFGE+AL+ ++ R A+V Sbjct: 90 LLDPEPILLHKGA-SFGEVALLKDLRRNATV 119 >UniRef50_Q30Y06 Cluster: Transcriptional regulator, Crp/Fnr family; n=3; Desulfovibrio|Rep: Transcriptional regulator, Crp/Fnr family - Desulfovibrio desulfuricans (strain G20) Length = 248 Score = 46.4 bits (105), Expect = 4e-04 Identities = 21/79 (26%), Positives = 39/79 (49%) Frame = +2 Query: 167 ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEK 346 I LF L AQQ++ + ++ + G+ + +G + Y++ +G + T D E Sbjct: 31 IPLFSGLSAQQLESMASIAVDRPVDKGQIIFVEGTRAEGLYIVLDGRVKIFKTAPDGREA 90 Query: 347 VVHTYEGSGSFGELALMYN 403 V+H + FGE+A+ N Sbjct: 91 VMHVFGAGEPFGEVAVFQN 109 >UniRef50_Q7CWQ8 Cluster: AGR_C_4670p; n=6; Rhizobiaceae|Rep: AGR_C_4670p - Agrobacterium tumefaciens (strain C58 / ATCC 33970) Length = 162 Score = 46.4 bits (105), Expect = 4e-04 Identities = 27/95 (28%), Positives = 47/95 (49%) Frame = +2 Query: 152 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 331 + ++ + F ++ +++ + A G+ + RQGD GD YV+ G DVLV Sbjct: 19 QMLKRVPFFSEMEPSKLKLLAFASDRVSYHAGDTLFRQGDVGDAAYVLLTGKVDVLVDSP 78 Query: 332 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 KV G+ GE+A++ + R A++RA T Sbjct: 79 SGTLKVAE-MTGNAIVGEIAILCDSVRTATIRAST 112 >UniRef50_A6G5Y4 Cluster: Protein phosphatase/cyclic nucleotide-binding domain protein; n=1; Plesiocystis pacifica SIR-1|Rep: Protein phosphatase/cyclic nucleotide-binding domain protein - Plesiocystis pacifica SIR-1 Length = 433 Score = 46.4 bits (105), Expect = 4e-04 Identities = 31/107 (28%), Positives = 53/107 (49%), Gaps = 3/107 (2%) Frame = +2 Query: 113 VFPKSDAQRARLA---EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDN 283 V P D +R ++ + +R I LF L+ ++ ++ + GE ++R+GD+ D Sbjct: 262 VRPADDQRRRQVVNNLQTLRHIALFMDLNDSELVRIFRRFQARDYGQGEVILREGDNADC 321 Query: 284 FYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASV 424 +V+ G DV V R K + T FGE+ L+ PR+A+V Sbjct: 322 LFVLVEG--DVRV---GRAGKTLTTLSRGAHFGEMGLLNQRPRSATV 363 >UniRef50_Q695H0 Cluster: CGMP-dependent protein kinase; n=1; Chlamydomonas reinhardtii|Rep: CGMP-dependent protein kinase - Chlamydomonas reinhardtii Length = 1027 Score = 46.4 bits (105), Expect = 4e-04 Identities = 29/87 (33%), Positives = 46/87 (52%), Gaps = 4/87 (4%) Frame = +2 Query: 146 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSE--PGEYVIRQGDDGDNFYVIENGVFDVL 319 ++ +R + F+ L +QM+ +LD F+ R E G+ ++ QGD + YV++ G L Sbjct: 418 VSAVIRSLPQFKGLKQEQMENILD-RFDAREELMQGDTILNQGDMLEKLYVVKIGEI-AL 475 Query: 320 VTGDDRVE--KVVHTYEGSGSFGELAL 394 D+RVE VH G FGE A+ Sbjct: 476 FRNDERVEDPNFVHEIAGFSYFGETAI 502 Score = 38.3 bits (85), Expect = 0.099 Identities = 29/117 (24%), Positives = 56/117 (47%), Gaps = 15/117 (12%) Frame = +2 Query: 146 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQG---DDGDNFYVIENGVFDV 316 + EA++ +F+ + + +V+ M+ + G V++QG D Y ++ G +V Sbjct: 157 ILEALKRNFVFKGIPQNHLVEVVGRMYGISFKSGAVVLQQGALPKQDDCMYYLQQGEAEV 216 Query: 317 LVTGDDRVEK-----------VVHTYEGSG-SFGELALMYNMPRAASVRAQTAGALW 451 +++G K V + G FG++AL+++ PR ASV A+T +W Sbjct: 217 VISGGADASKNHGEERKVDGHTVRIPQKPGWLFGDVALLFHSPRTASVVAKTNITVW 273 >UniRef50_A5PH37 Cluster: AKT2 inward rectifier channel; n=6; Embryophyta|Rep: AKT2 inward rectifier channel - Physcomitrella patens (Moss) Length = 967 Score = 46.4 bits (105), Expect = 4e-04 Identities = 32/120 (26%), Positives = 54/120 (45%), Gaps = 3/120 (2%) Frame = +2 Query: 98 EGAPAVFPK---SDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQG 268 +G AV PK S + E V + LF + Q++ M + P E +I Sbjct: 361 QGTMAVLPKAIRSSIAQYLFLETVEKVYLFHGTSYNFLTQLVTEMKAEYFPPREEIILFN 420 Query: 269 DDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGAL 448 + FY++ NG DV +T D E+++ T GE+ ++ MP+ +VR++ L Sbjct: 421 EAPSEFYIVVNGSVDV-ITMKDASEQILFTAVTGDVIGEIGVLCYMPQPFTVRSRKLSQL 479 >UniRef50_Q4CSS9 Cluster: Protein kinase, putative; n=2; Trypanosoma cruzi|Rep: Protein kinase, putative - Trypanosoma cruzi Length = 922 Score = 46.4 bits (105), Expect = 4e-04 Identities = 32/118 (27%), Positives = 56/118 (47%), Gaps = 2/118 (1%) Frame = +2 Query: 104 APAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQ-GDDGD 280 +P V KS + + V LF ++D + ++ A+ G ++RQ G + Sbjct: 208 SPPVVAKSPEEERIVRAGVMACHLFSNMDNKDQSIIVQALKRVTFPAGTDILRQDGASVE 267 Query: 281 NFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPR-AASVRAQTAGALW 451 +++ G DV+ G K VHT +FGE+ +MYN+P A++R+ T L+ Sbjct: 268 KLFLLTQGSCDVIKNG-----KRVHTLLECSTFGEMEMMYNLPTCVATIRSVTNCVLY 320 Score = 34.7 bits (76), Expect = 1.2 Identities = 23/99 (23%), Positives = 42/99 (42%) Frame = +2 Query: 134 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 313 +R + + + R Q+ +A+ K G+Y+IR G+ G ++I G Sbjct: 338 KREKYEALLSNVQFLREFSDYDRMQIAEALVTKTYRQGDYIIRFGETGKWMHIIVEGEVA 397 Query: 314 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 430 V+ + +++ EG GEL ++N A V A Sbjct: 398 VVGRHIGKKCEILRLKEGE-VVGELEFLFNDLTVADVIA 435 >UniRef50_Q23EB4 Cluster: ABC transporter family protein; n=3; Tetrahymena thermophila SB210|Rep: ABC transporter family protein - Tetrahymena thermophila SB210 Length = 2778 Score = 46.4 bits (105), Expect = 4e-04 Identities = 25/95 (26%), Positives = 46/95 (48%), Gaps = 2/95 (2%) Frame = +2 Query: 152 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV--T 325 + ++ +F Q + +++ M E PGE + ++GD D+ Y+I +G ++ + T Sbjct: 2226 KTIQKFKIFNCFHQQTINKIIFQMKEITVSPGEAIFQEGDLDDSIYLILSGQIEIFLKET 2285 Query: 326 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 430 D ++ T FGE+A PR AS R+ Sbjct: 2286 KRDSHSFILKTLSTDQIFGEIAFFSEQPRTASARS 2320 >UniRef50_A0CY63 Cluster: Chromosome undetermined scaffold_301, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_301, whole genome shotgun sequence - Paramecium tetraurelia Length = 785 Score = 46.4 bits (105), Expect = 4e-04 Identities = 28/57 (49%), Positives = 34/57 (59%), Gaps = 5/57 (8%) Frame = +2 Query: 242 PGEYVIRQGDDGDNFYVIENGVFDVLV----TGDDRV-EKVVHTYEGSGSFGELALM 397 PGEYV QGD GDN +VI +G DV + T D V E+VV + FGELA+M Sbjct: 297 PGEYVFHQGDFGDNLFVILSGSVDVKIEKKFTQDGPVIEQVVSSLYDGQHFGELAMM 353 >UniRef50_Q8WZA2 Cluster: Rap guanine nucleotide exchange factor 4; n=53; Coelomata|Rep: Rap guanine nucleotide exchange factor 4 - Homo sapiens (Human) Length = 1011 Score = 46.4 bits (105), Expect = 4e-04 Identities = 24/68 (35%), Positives = 41/68 (60%) Frame = +2 Query: 221 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 400 +FE ++ G + QG++G ++Y+I G +V++ G + VV T FG+LAL+ Sbjct: 373 IFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYG----KGVVCTLHEGDDFGKLALVN 428 Query: 401 NMPRAASV 424 + PRAAS+ Sbjct: 429 DAPRAASI 436 Score = 35.5 bits (78), Expect = 0.70 Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 2/99 (2%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV--TGD 331 ++ + F + Q+ + + E G + RQGD G N+Y + G DV V T Sbjct: 38 LKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSS 97 Query: 332 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGAL 448 + + T +FGE +++ N PR A++ + + L Sbjct: 98 HQDAVTICTLGIGTAFGE-SILDNTPRHATIVTRESSEL 135 >UniRef50_Q2K3Q8 Cluster: Probable cation transporter protein; n=2; Rhizobium|Rep: Probable cation transporter protein - Rhizobium etli (strain CFN 42 / ATCC 51251) Length = 581 Score = 46.0 bits (104), Expect = 5e-04 Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 1/97 (1%) Frame = +2 Query: 143 RLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDV-L 319 ++ + + LF + +++L K + PGE VIR+GD GD+ Y I +G +V L Sbjct: 440 KMQQLIETFPLFSQVGEDAQEELLLLFKAKSAPPGERVIRRGDRGDSMYFISSGAVEVRL 499 Query: 320 VTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 430 +G R+E FGE+AL+ R A V A Sbjct: 500 ASGAIRLEP-------GAFFGEMALLSGGRRTADVIA 529 >UniRef50_Q7RDH4 Cluster: Reticulocyte-binding protein 2 homolog A, putative; n=7; Plasmodium (Vinckeia)|Rep: Reticulocyte-binding protein 2 homolog A, putative - Plasmodium yoelii yoelii Length = 1939 Score = 46.0 bits (104), Expect = 5e-04 Identities = 26/103 (25%), Positives = 52/103 (50%), Gaps = 1/103 (0%) Frame = +2 Query: 146 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 325 + + ++ + + R L + + + +M + EP +I++GD D FY+I G+ V + Sbjct: 1737 ILQVLKNVPILRYLPLEILDNISYSMKIEIHEPNHTIIKEGDYDDKFYIICKGLATVDIP 1796 Query: 326 GDDRVEK-VVHTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 K ++ + + + FGEL+L+ N R A+V T L+ Sbjct: 1797 SKFSYNKLIISSLKKADYFGELSLINNTARTANVVLDTTSILF 1839 Score = 42.7 bits (96), Expect = 0.005 Identities = 19/67 (28%), Positives = 40/67 (59%) Frame = +2 Query: 248 EYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVR 427 +++IRQ DD +FY++++G ++ D V++T FGE+++++NM R +V Sbjct: 558 QFIIRQHDDPLDFYILKDGEVNIYYNNAD---NVINTLSAYSFFGEISIIFNMLRTCNVA 614 Query: 428 AQTAGAL 448 ++ A+ Sbjct: 615 VKSDKAI 621 >UniRef50_A0DKC6 Cluster: Chromosome undetermined scaffold_54, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_54, whole genome shotgun sequence - Paramecium tetraurelia Length = 503 Score = 46.0 bits (104), Expect = 5e-04 Identities = 29/74 (39%), Positives = 41/74 (55%), Gaps = 2/74 (2%) Frame = +2 Query: 221 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT--GDDRVEKVVHTYEGSGSFGELAL 394 MF ++ + E V G FYVI +G +VL+ G D +E V +G SFGELAL Sbjct: 58 MFIEKFQSTEVVFHLDTIGTKFYVILDGQVEVLIRRRGFDELESVRILKKGE-SFGELAL 116 Query: 395 MYNMPRAASVRAQT 436 ++ PR A++R T Sbjct: 117 IHKQPRLATIRCVT 130 Score = 32.7 bits (71), Expect = 4.9 Identities = 13/50 (26%), Positives = 27/50 (54%) Frame = +2 Query: 167 ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDV 316 I +F L+ Q+ + F E + V+++G+ D+F +++ G+F V Sbjct: 164 ISIFNQLNRTQLTSIYLNSFLYEYEKNQVVVQEGEKSDSFLIVKQGLFQV 213 >UniRef50_Q9P1Z3 Cluster: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3; n=61; Eukaryota|Rep: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 - Homo sapiens (Human) Length = 774 Score = 46.0 bits (104), Expect = 5e-04 Identities = 32/99 (32%), Positives = 47/99 (47%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 352 LF D + VL + + +PG+ V+R+G G Y I++G+ VL G + Sbjct: 428 LFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLARG----ARDT 483 Query: 353 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWGHGPPH 469 +GS FGE+ L+ R ASVRA T L+ H Sbjct: 484 RLTDGS-YFGEICLLTRGRRTASVRADTYCRLYSLSVDH 521 >UniRef50_UPI0000EC9E1A Cluster: Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP).; n=1; Gallus gallus|Rep: Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP). - Gallus gallus Length = 766 Score = 45.6 bits (103), Expect = 7e-04 Identities = 24/68 (35%), Positives = 37/68 (54%) Frame = +2 Query: 221 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 400 MFE G + QGD G ++Y++ G +V+ G + +V T FG+LAL+ Sbjct: 189 MFESHQRAGTVLFSQGDKGTSWYIVWKGSVNVVTHG----KGLVATLHEGDDFGQLALVN 244 Query: 401 NMPRAASV 424 + PRAAS+ Sbjct: 245 DAPRAASI 252 >UniRef50_Q2WA28 Cluster: CheY-like receiver; n=3; Magnetospirillum|Rep: CheY-like receiver - Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) Length = 328 Score = 45.6 bits (103), Expect = 7e-04 Identities = 27/68 (39%), Positives = 39/68 (57%), Gaps = 1/68 (1%) Frame = +2 Query: 230 KRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEG-SGSFGELALMYNM 406 K+ G+ V +GD GD YV+E+G + T + +KV+ G +G FGE+AL+ N Sbjct: 206 KKFHAGQIVFSEGDAGDMAYVVESGKVSIFKTVNG--QKVILGQIGPNGVFGEMALIDNE 263 Query: 407 PRAASVRA 430 PR AS A Sbjct: 264 PRMASAMA 271 >UniRef50_Q1YDI6 Cluster: Possible cAMP-dependent regulatory protein; n=1; Aurantimonas sp. SI85-9A1|Rep: Possible cAMP-dependent regulatory protein - Aurantimonas sp. SI85-9A1 Length = 158 Score = 45.6 bits (103), Expect = 7e-04 Identities = 26/95 (27%), Positives = 50/95 (52%) Frame = +2 Query: 152 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 331 + +R + +F ++ +++ + G+ + RQG+ GD+ YVI G DV + + Sbjct: 9 DLLRSVPIFAGMEPSRLKLIAFTSDSIAYRQGQVMCRQGERGDSAYVIVAGKADVSIETE 68 Query: 332 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 D + VV T GE+A++ + PR A+V A++ Sbjct: 69 DG-DFVVATLGPGDVVGEIAILCDTPRTATVTAKS 102 >UniRef50_Q09BB3 Cluster: PKA regulatory subunit-like protein; n=1; Stigmatella aurantiaca DW4/3-1|Rep: PKA regulatory subunit-like protein - Stigmatella aurantiaca DW4/3-1 Length = 415 Score = 45.6 bits (103), Expect = 7e-04 Identities = 27/98 (27%), Positives = 50/98 (51%), Gaps = 1/98 (1%) Frame = +2 Query: 146 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEP-GEYVIRQGDDGDNFYVIENGVFDVLV 322 L++ + LFR L +Q ++ + F+ S P G+ ++ QG D Y++ NG V++ Sbjct: 263 LSQTISTHALFRGLSREQ-KEAMTRDFQLCSVPVGKTLVEQGQPVDALYLLLNGHCQVVL 321 Query: 323 TGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 D + E FGE++++ N+P +VRA + Sbjct: 322 DEDTERASPLPALEEGDVFGEISMLLNVPATVTVRADS 359 >UniRef50_A7BRS9 Cluster: Transcriptional Regulator, Crp/Fnr family; n=1; Beggiatoa sp. PS|Rep: Transcriptional Regulator, Crp/Fnr family - Beggiatoa sp. PS Length = 248 Score = 45.6 bits (103), Expect = 7e-04 Identities = 26/88 (29%), Positives = 45/88 (51%) Frame = +2 Query: 152 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 331 + ++ I LF L+ QQ Q+ M R E GEY+ + G ++F++++ G +L Sbjct: 14 QELQKIYLFSGLNDQQFTQIKQGMRPIRLEDGEYLFKHGQRAEHFFMLKEGYIKLLRLSL 73 Query: 332 DRVEKVVHTYEGSGSFGELALMYNMPRA 415 + EKV +F E A+M+ MP + Sbjct: 74 EGAEKVFEVVSPGQTFAE-AIMF-MPNS 99 >UniRef50_A6G7H5 Cluster: Serine/threonine-protein kinase; n=2; Plesiocystis pacifica SIR-1|Rep: Serine/threonine-protein kinase - Plesiocystis pacifica SIR-1 Length = 547 Score = 45.6 bits (103), Expect = 7e-04 Identities = 25/65 (38%), Positives = 38/65 (58%) Frame = +2 Query: 242 PGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAAS 421 PG+++IR+ + GD Y+I G +V + D R E + + G FGE A++ + PR AS Sbjct: 347 PGDWIIREDEVGDAAYIILTGSCEVFKSIDGRWESLRKLHAGE-VFGETAILASTPRTAS 405 Query: 422 VRAQT 436 V A T Sbjct: 406 VVALT 410 >UniRef50_A5UZM8 Cluster: Cyclic nucleotide-binding protein; n=3; Chloroflexaceae|Rep: Cyclic nucleotide-binding protein - Roseiflexus sp. RS-1 Length = 167 Score = 45.6 bits (103), Expect = 7e-04 Identities = 28/98 (28%), Positives = 45/98 (45%), Gaps = 4/98 (4%) Frame = +2 Query: 143 RLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV 322 R+ E +R + +F L ++ QV R+ + V +GD GD Y++ G V++ Sbjct: 4 RVLENLRKVEIFAGLSDDELMQVAGVCRAIRTPASQTVFNEGDTGDELYIVHEGTVRVMI 63 Query: 323 T---GDDRV-EKVVHTYEGSGSFGELALMYNMPRAASV 424 T D V ++T FGE AL+ R A+V Sbjct: 64 TTRLSDGTVAPSTINTLYPGQCFGEQALLGGAARTATV 101 >UniRef50_A0YLS1 Cluster: Putative uncharacterized protein; n=1; Lyngbya sp. PCC 8106|Rep: Putative uncharacterized protein - Lyngbya sp. PCC 8106 Length = 486 Score = 45.6 bits (103), Expect = 7e-04 Identities = 22/105 (20%), Positives = 53/105 (50%) Frame = +2 Query: 119 PKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIE 298 P Q L + ++ ++ F + ++ +++ + + +++ +GD GD F++I Sbjct: 314 PVYSPQDLSLRDLLKKVVYFENFSNLEILSLIEKGYRQTYYSEQFIFHEGDPGDAFHIIL 373 Query: 299 NGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQ 433 +G +++ ++ K + FGEL+L+ + R+A VRA+ Sbjct: 374 SGSVEIIA---EKANKHIRDLYAGDFFGELSLLMGIRRSAGVRAK 415 >UniRef50_A0YAY7 Cluster: CAMP-binding protein-catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; n=1; marine gamma proteobacterium HTCC2143|Rep: CAMP-binding protein-catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase - marine gamma proteobacterium HTCC2143 Length = 361 Score = 45.6 bits (103), Expect = 7e-04 Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 1/93 (1%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVE-KV 349 LF + ++++LD + G+ ++RQG+ GD Y I+ GV V +++ + Sbjct: 154 LFYKVPPMNIRKILDKFSAHYASAGDTILRQGELGDCCYYIKEGVAGVYQAENEKSSPSL 213 Query: 350 VHTYEGSGSFGELALMYNMPRAASVRAQTAGAL 448 V + FGE AL+ + PR A++ T G L Sbjct: 214 VAELDVGRCFGEDALVNDAPRNATITMHTNGVL 246 >UniRef50_Q554K9 Cluster: CGMP-stimulated cGMP phosphodiesterase; n=2; Dictyostelium discoideum|Rep: CGMP-stimulated cGMP phosphodiesterase - Dictyostelium discoideum AX4 Length = 867 Score = 45.6 bits (103), Expect = 7e-04 Identities = 29/108 (26%), Positives = 56/108 (51%) Frame = +2 Query: 113 VFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYV 292 V S ++ + + V + +FRS+ Q ++L +++ G +I + + D FYV Sbjct: 587 VMKSSHSEAVDILKLVESVDIFRSIPLTQACEILQTATKRKYSQGSVIIARDTEPDAFYV 646 Query: 293 IENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 + +GV V + G+ + +V Y FGE++L+ R+A+V+A T Sbjct: 647 VASGVVCVNI-GELKKNLIVGDY-----FGEMSLVMGGLRSANVQAVT 688 >UniRef50_A7SKJ5 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 2425 Score = 45.6 bits (103), Expect = 7e-04 Identities = 22/63 (34%), Positives = 35/63 (55%) Frame = +2 Query: 248 EYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVR 427 EY++RQG+ G Y I+ G +VL DR + FGE+++++N PR S+R Sbjct: 1760 EYIVRQGEIGHEMYFIQKGDVEVL----DRDGNALAVLGPGSFFGEVSVLFNTPRTTSIR 1815 Query: 428 AQT 436 +T Sbjct: 1816 TRT 1818 Score = 40.7 bits (91), Expect = 0.019 Identities = 21/63 (33%), Positives = 38/63 (60%) Frame = +2 Query: 242 PGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAAS 421 P + ++++G+ G + I G ++ DD + + + EG FGE++L+YNM RA++ Sbjct: 743 PSQMIVKKGETGQSICYIHKGKAEIY--DDDDITQSIVLEEGY-IFGEVSLVYNMLRASN 799 Query: 422 VRA 430 VRA Sbjct: 800 VRA 802 Score = 39.9 bits (89), Expect = 0.032 Identities = 27/105 (25%), Positives = 48/105 (45%) Frame = +2 Query: 122 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 301 + D + +R + LF D ++Q+ +PG+Y++ GD G Y I Sbjct: 1204 QQDVCEQESTDILREVPLFIECDENFIKQLSLCTTSYIFKPGDYIVYAGDMGREMYCIRR 1263 Query: 302 GVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 G ++L D+ ++VV T FGE+ L+ R +V+ +T Sbjct: 1264 GQVNIL--NDE--DEVVGTLGPGSFFGEIGLVCGESRVYTVQCKT 1304 Score = 33.1 bits (72), Expect = 3.7 Identities = 18/63 (28%), Positives = 34/63 (53%) Frame = +2 Query: 248 EYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVR 427 +Y++ +GD G +I+ G +V +TG+D +V+ E +G+ L+ P ++R Sbjct: 2322 DYILHKGDIGQQLIIIKRGTAEV-ITGED--PEVILPLEEMSFYGDRYLLAPGPHLETLR 2378 Query: 428 AQT 436 A T Sbjct: 2379 AVT 2381 >UniRef50_Q7UTR3 Cluster: ATP-binding subunit of ABC transporter; n=1; Pirellula sp.|Rep: ATP-binding subunit of ABC transporter - Rhodopirellula baltica Length = 397 Score = 45.2 bits (102), Expect = 9e-04 Identities = 33/117 (28%), Positives = 50/117 (42%), Gaps = 3/117 (2%) Frame = +2 Query: 134 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 313 + A L E + +F + + ++ +M PG+ ++ GD GD FY+I G Sbjct: 262 EAAVLGEMLSQCSVFSGVAISTLTELSRSMTRTTHGPGDRIVTYGDVGDRFYLIREGTVS 321 Query: 314 V---LVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWGHGPPHVS 475 V G + +V EG+ FGE AL+ PR A V A T + P S Sbjct: 322 VKQPTQPGGNDFREVAQLGEGA-YFGETALLTGEPRNAHVDATTETVTYSLDAPTFS 377 >UniRef50_Q5P0W6 Cluster: Transcriptional regulator, Dnr/Nnr type; n=2; Azoarcus|Rep: Transcriptional regulator, Dnr/Nnr type - Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) Length = 229 Score = 45.2 bits (102), Expect = 9e-04 Identities = 26/90 (28%), Positives = 40/90 (44%) Frame = +2 Query: 140 ARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL 319 A + +R I F L A + +V E+ E GE + ++GD F+ + +G + Sbjct: 6 ADIPTLLRQISFFSELSADDIDRVARYTRERTLEKGEVLFQRGDPVHGFFFVVSGQMKLA 65 Query: 320 VTGDDRVEKVVHTYEGSGSFGELALMYNMP 409 V+ EKVV SFGE + N P Sbjct: 66 VSSAQGNEKVVEIISPMNSFGEAVMFLNRP 95 >UniRef50_Q1PUQ2 Cluster: Similar to transcriptional regulator of Crp/Fnr family; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Similar to transcriptional regulator of Crp/Fnr family - Candidatus Kuenenia stuttgartiensis Length = 228 Score = 45.2 bits (102), Expect = 9e-04 Identities = 24/88 (27%), Positives = 43/88 (48%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 337 ++ + LF SL +Q++ + A K + Q D GD FY++ G + + +D Sbjct: 10 LKNVPLFNSLANEQLKTLFRAGITKSFPKDHVIFYQHDHGDTFYIVITGKVKITLLNEDG 69 Query: 338 VEKVVHTYEGSGSFGELALMYNMPRAAS 421 E V+ + FGE++LM + R+ S Sbjct: 70 KEIVLSLLKEGDFFGEMSLMDDETRSVS 97 >UniRef50_Q8ILS1 Cluster: Putative uncharacterized protein; n=1; Plasmodium falciparum 3D7|Rep: Putative uncharacterized protein - Plasmodium falciparum (isolate 3D7) Length = 838 Score = 45.2 bits (102), Expect = 9e-04 Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 1/98 (1%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 337 +R + + R L +++ Q+ AM + P +I+ D FY+I G+ V + Sbjct: 591 LRNVPILRYLSEEELVQISYAMKLEMYHPNHTIIKANTYDDKFYIICKGLVTVEKNTEGN 650 Query: 338 VEKVV-HTYEGSGSFGELALMYNMPRAASVRAQTAGAL 448 +K+V + + FGELAL+ N+ R A+V T L Sbjct: 651 KDKIVLSNLKKTDYFGELALIKNIKRTANVILDTEAIL 688 >UniRef50_Q23DN4 Cluster: Cyclic nucleotide-binding domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 809 Score = 45.2 bits (102), Expect = 9e-04 Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 1/85 (1%) Frame = +2 Query: 167 ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEK 346 I +F S+ + + +L + E+ +PGEYVIRQG G FY + +G+ + DD + Sbjct: 544 IEIFESISIKNFRDLLQSAKEEYYDPGEYVIRQGTIGTKFYFVMSGIVCIF---DD--AR 598 Query: 347 VVHTYEGSGS-FGELALMYNMPRAA 418 + + +GS FGE AL + R A Sbjct: 599 SLSRFCPTGSYFGETALKVDSTRRA 623 >UniRef50_A0DVS8 Cluster: Chromosome undetermined scaffold_66, whole genome shotgun sequence; n=5; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_66, whole genome shotgun sequence - Paramecium tetraurelia Length = 637 Score = 45.2 bits (102), Expect = 9e-04 Identities = 26/66 (39%), Positives = 40/66 (60%), Gaps = 4/66 (6%) Frame = +2 Query: 245 GEYVIRQGDDGDNFYVIENGVFDV----LVTGDDRVEKVVHTYEGSGSFGELALMYNMPR 412 G+ + R+GD G FY+I G + LV + + ++++ +G G FGELAL N PR Sbjct: 106 GQTLFREGDVGTTFYIILQGRVSIHKRLLVQEEFQDKELIQLQDGQG-FGELALENNEPR 164 Query: 413 AASVRA 430 +ASV+A Sbjct: 165 SASVKA 170 >UniRef50_O95398 Cluster: Rap guanine nucleotide exchange factor 3; n=33; Euteleostomi|Rep: Rap guanine nucleotide exchange factor 3 - Homo sapiens (Human) Length = 881 Score = 45.2 bits (102), Expect = 9e-04 Identities = 24/68 (35%), Positives = 39/68 (57%) Frame = +2 Query: 221 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 400 +FE S+ G + QGD G ++Y+I G +V+ G + +V T FG+LAL+ Sbjct: 220 LFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHG----KGLVTTLHEGDDFGQLALVN 275 Query: 401 NMPRAASV 424 + PRAA++ Sbjct: 276 DAPRAATI 283 >UniRef50_UPI000065E24B Cluster: Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP).; n=1; Takifugu rubripes|Rep: Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP). - Takifugu rubripes Length = 908 Score = 44.8 bits (101), Expect = 0.001 Identities = 24/68 (35%), Positives = 40/68 (58%) Frame = +2 Query: 221 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 400 +FE ++ G + QGD G ++Y+I G +V+ G V + +EG FG+LAL+ Sbjct: 172 VFESHAKAGTVLFSQGDKGTSWYIIWKGSVNVITHGKGLVTTL---HEGE-DFGQLALLN 227 Query: 401 NMPRAASV 424 + PRAA++ Sbjct: 228 DAPRAATI 235 >UniRef50_UPI000065D7C1 Cluster: Homolog of Oncorhynchus mykiss "Hyperpolarization-activated cyclic nucleotide-gated cation channel 1.; n=1; Takifugu rubripes|Rep: Homolog of Oncorhynchus mykiss "Hyperpolarization-activated cyclic nucleotide-gated cation channel 1. - Takifugu rubripes Length = 783 Score = 44.8 bits (101), Expect = 0.001 Identities = 26/93 (27%), Positives = 50/93 (53%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 337 V + LF + D + +L + + +P +Y++R+G G + I++GV +L G+ Sbjct: 391 VASMPLFANADPNFVTAMLTKLRFEVFQPKDYIVREGTIGKKMFFIQHGVVSILTKGNIS 450 Query: 338 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 ++ + +Y FGE+ L+ R ASV+A+T Sbjct: 451 MKLMDGSY-----FGEICLLTRGRRTASVQAET 478 >UniRef50_Q92SD2 Cluster: PUTATIVE TRANSCRIPTION REGULATOR PROTEIN; n=2; Sinorhizobium|Rep: PUTATIVE TRANSCRIPTION REGULATOR PROTEIN - Rhizobium meliloti (Sinorhizobium meliloti) Length = 234 Score = 44.8 bits (101), Expect = 0.001 Identities = 23/93 (24%), Positives = 44/93 (47%) Frame = +2 Query: 161 RGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRV 340 R +F D++ + ++ ++ G + ++GD GD V+ +G + + Sbjct: 12 RSFPIFEEFDSETLCELSGIASYRKWSAGTVIFQRGDQGDYMIVVVSGRIKLSLFTPQGR 71 Query: 341 EKVVHTYEGSGSFGELALMYNMPRAASVRAQTA 439 E ++ +E FGE+AL+ PR+A A TA Sbjct: 72 ELMLRQHEAGALFGEMALLDGQPRSADATAVTA 104 >UniRef50_Q6ANR0 Cluster: Related to nitrogen assimilation regulatory protein; n=1; Desulfotalea psychrophila|Rep: Related to nitrogen assimilation regulatory protein - Desulfotalea psychrophila Length = 881 Score = 44.8 bits (101), Expect = 0.001 Identities = 26/87 (29%), Positives = 41/87 (47%) Frame = +2 Query: 170 LLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKV 349 +LF+ L +++ + + + GEYV RQG D Y++ G +++ D Sbjct: 14 VLFQDLSPEEIGRCSEMAMVEIVPMGEYVYRQGGQTDLLYLVAVGEAELVFEFDTSSVSA 73 Query: 350 VHTYEGSGSFGELALMYNMPRAASVRA 430 V G FGE AL+ P A +VRA Sbjct: 74 VGRVGPGGHFGETALLTGKPHAVAVRA 100 >UniRef50_Q935V9 Cluster: Transcriptional regulator with cyclic nucleotide-binding domain; n=2; Streptomyces|Rep: Transcriptional regulator with cyclic nucleotide-binding domain - Streptomyces sp. EC3 Length = 227 Score = 44.8 bits (101), Expect = 0.001 Identities = 22/68 (32%), Positives = 37/68 (54%) Frame = +2 Query: 239 EPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAA 418 E GE ++R+G+ G + Y++ +G + V+ +D E ++ G GELA +PR A Sbjct: 48 EKGERLLREGEQGSHVYLLLSGWYKVVARTEDDREALMAVRTGGDIVGELACFGTLPRVA 107 Query: 419 SVRAQTAG 442 +V A G Sbjct: 108 TVMAAGPG 115 >UniRef50_Q1DAY2 Cluster: Cyclic nucleotide-binding domain protein; n=2; Cystobacterineae|Rep: Cyclic nucleotide-binding domain protein - Myxococcus xanthus (strain DK 1622) Length = 152 Score = 44.8 bits (101), Expect = 0.001 Identities = 24/101 (23%), Positives = 47/101 (46%) Frame = +2 Query: 149 AEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTG 328 A ++ + LF L Q+ +V + G ++ R+G+ G +VI G + + Sbjct: 3 AAVLKKVALFEGLTQGQLAKVAQIGHSRTYPAGAFLFREGETGQEMFVIAEGKVRISKSV 62 Query: 329 DDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 E+ + E FGE+A++ + PR+A A + ++W Sbjct: 63 PGIGEEALAILEPGQYFGEMAVIEDSPRSADAIAHVSCSVW 103 >UniRef50_A4M043 Cluster: Transcriptional regulator, Crp/Fnr family; n=1; Geobacter bemidjiensis Bem|Rep: Transcriptional regulator, Crp/Fnr family - Geobacter bemidjiensis Bem Length = 238 Score = 44.8 bits (101), Expect = 0.001 Identities = 25/91 (27%), Positives = 45/91 (49%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 337 +R I LF LD + +V + EKR + V+ + D + Y++ G V+ G + Sbjct: 18 LRAIPLFSCLDPLEFSEVQRRIMEKRFHKNQVVLLEEDTANYMYIVYGGKVRVVHLGSEG 77 Query: 338 VEKVVHTYEGSGSFGELALMYNMPRAASVRA 430 E+++ ++ FGE+AL+ A+V A Sbjct: 78 SERILAVHKRGDVFGEMALLDAKTAPATVIA 108 >UniRef50_A4RUE3 Cluster: Predicted protein; n=1; Ostreococcus lucimarinus CCE9901|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 121 Score = 44.8 bits (101), Expect = 0.001 Identities = 33/109 (30%), Positives = 50/109 (45%), Gaps = 10/109 (9%) Frame = +2 Query: 134 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG-VF 310 +R R + I +F L + + V+ +PGE +IRQG+ D FYVI G Sbjct: 1 RRLRYERTLAKIPVFADLGSYERAMVVKQAKRFSFKPGEKIIRQGEVADKFYVILKGSAV 60 Query: 311 DVLVTGD-DRV--------EKVVHTYEGSGSFGELALMYNMPRAASVRA 430 GD D V ++++ + FGELAL+ PR A++ A Sbjct: 61 STKSDGDVDHVAPGSKIPPDRIMRNFSQGQYFGELALLTGQPRLATIVA 109 >UniRef50_UPI00006CFEF7 Cluster: cation channel family protein; n=1; Tetrahymena thermophila SB210|Rep: cation channel family protein - Tetrahymena thermophila SB210 Length = 1392 Score = 44.4 bits (100), Expect = 0.002 Identities = 36/162 (22%), Positives = 67/162 (41%), Gaps = 13/162 (8%) Frame = +2 Query: 5 YFVKKPPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPK-SDAQRARLAEAVRGILL-- 175 Y +K +R +S Y ++D + E VF K S+ R + + + G ++ Sbjct: 607 YLNRKNVNISLKSRVRSYLVFLYKEQKDRNQEAEEKVFQKLSNKLRREIVQEINGKIVNS 666 Query: 176 ----FRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGD-NFYVIENGVFDVLVTGDDRV 340 ++ + + +++ AM E P E + +GD D + Y I+ G D+ D Sbjct: 667 CGIFTKNFSSSTINKIIFAMKECVVSPNEIIFNEGDQDDMSIYFIQGGYVDIFQQNDSDK 726 Query: 341 EK-----VVHTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 K V+ + FGEL+ +PR A ++ L+ Sbjct: 727 NKQSNQRVIKRLGQNQIFGELSFFSGLPRKAGAKSVNLTTLY 768 >UniRef50_Q7D4Z5 Cluster: Drug transporter; n=19; Mycobacterium|Rep: Drug transporter - Mycobacterium tuberculosis Length = 1071 Score = 44.4 bits (100), Expect = 0.002 Identities = 44/137 (32%), Positives = 60/137 (43%) Frame = +2 Query: 20 PPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQ 199 PPVA RR A P A A PK+ ++ L EA+R F D QQ Sbjct: 504 PPVAPLGARRPPRPAPVASPA------AAVAPTPKT-SREVNLLEALR----FARPDTQQ 552 Query: 200 MQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF 379 ++ + G Y+ GD D YV+ +G VL GD ++VV Sbjct: 553 IEL----------QAGSYLFHAGDVSDALYVVRSGRLQVLA-GDGAKDEVVAELGRGQVV 601 Query: 380 GELALMYNMPRAASVRA 430 GEL ++ + PR+ASVRA Sbjct: 602 GELGVLLDAPRSASVRA 618 >UniRef50_Q2YZI3 Cluster: Putative uncharacterized protein; n=1; uncultured gamma proteobacterium|Rep: Putative uncharacterized protein - uncultured gamma proteobacterium Length = 354 Score = 44.4 bits (100), Expect = 0.002 Identities = 27/93 (29%), Positives = 49/93 (52%), Gaps = 1/93 (1%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL-VTGDDRVEKV 349 +F+ + +Q + M + GE VIRQG++G++FY+I +G V+ T + V Sbjct: 149 VFQRIPPGNIQSIFIRMQTHHFKAGEAVIRQGEEGEHFYIIRDGHCRVIRKTRKNPEGMV 208 Query: 350 VHTYEGSGSFGELALMYNMPRAASVRAQTAGAL 448 + + +FGE +L+ R AS+ ++ G L Sbjct: 209 LARLKAGDNFGEESLISGGKRNASIVMESDGVL 241 >UniRef50_A7BVI5 Cluster: Reductase; n=1; Beggiatoa sp. PS|Rep: Reductase - Beggiatoa sp. PS Length = 1008 Score = 44.4 bits (100), Expect = 0.002 Identities = 27/69 (39%), Positives = 36/69 (52%) Frame = +2 Query: 227 EKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNM 406 EK + GE V ++GD GD FY+I G V G K V SFGE+AL+ + Sbjct: 166 EKTFKDGEVVFQEGDIGDRFYLILEGTAKVTKNG-----KFVSRLNRGQSFGEVALVGDK 220 Query: 407 PRAASVRAQ 433 PR +V A+ Sbjct: 221 PRDVTVSAE 229 Score = 41.1 bits (92), Expect = 0.014 Identities = 35/111 (31%), Positives = 58/111 (52%), Gaps = 6/111 (5%) Frame = +2 Query: 119 PKSDA-QRARLAEAVRGIL----LFRSLD-AQQMQQVLDAMFEKRSEPGEYVIRQGDDGD 280 P+S A Q R+A+ + ++ LF+SL ++Q Q L+ M + E G + ++GD D Sbjct: 304 PESVAKQSGRVAQVRQNLVTESSLFKSLPFSEQSAQWLEEM---QFEDGAIIFQEGDVAD 360 Query: 281 NFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQ 433 FY+I +G+ + + EK+V FGE+AL+ N PR A+ Sbjct: 361 RFYLILSGMVKI-TKKEANDEKLVALLCRGQYFGEVALIRNEPRIVKAVAE 410 Score = 40.7 bits (91), Expect = 0.019 Identities = 21/84 (25%), Positives = 44/84 (52%), Gaps = 1/84 (1%) Frame = +2 Query: 149 AEAVR-GILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 325 A+++R + L ++L ++ Q++ E E + +GD G + Y+I++G VL T Sbjct: 7 AQSIRCNLPLLKTLSQEKQQELFAHAKILNVELDEIIFEEGDVGHSMYLIKSGAVRVLTT 66 Query: 326 GDDRVEKVVHTYEGSGSFGELALM 397 +D ++ + + FGE A++ Sbjct: 67 NEDGQPMILASLQSGDCFGEQAIL 90 >UniRef50_A1IBE9 Cluster: Putative transcriptional regulator, Crp/Fnr family; n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Putative transcriptional regulator, Crp/Fnr family - Candidatus Desulfococcus oleovorans Hxd3 Length = 275 Score = 44.4 bits (100), Expect = 0.002 Identities = 27/85 (31%), Positives = 47/85 (55%), Gaps = 2/85 (2%) Frame = +2 Query: 182 SLDAQQMQQVLDAMFEKRS-EPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHT 358 +++ ++ L F RS EPG+ + R+GD GD Y+I +G+ V +T + ++V Sbjct: 100 TMEEKEDHSSLPGGFATRSFEPGDVIFREGDPGDAAYLILSGL--VKITRQQKKTRLVLN 157 Query: 359 YEGSGS-FGELALMYNMPRAASVRA 430 G+ FGE+A++ PR A+ A Sbjct: 158 QLGADQIFGEMAMITGEPRTATATA 182 >UniRef50_A0NZP6 Cluster: CAAX amino terminal protease family protein; n=1; Stappia aggregata IAM 12614|Rep: CAAX amino terminal protease family protein - Stappia aggregata IAM 12614 Length = 379 Score = 44.4 bits (100), Expect = 0.002 Identities = 32/95 (33%), Positives = 47/95 (49%), Gaps = 5/95 (5%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAM-FEKRSEP---GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRV 340 +FR + Q+V DA+ R P E VI +G+ D Y++ G F + G + Sbjct: 21 IFRKMTEFMPQRVADAVQAASRKVPVAAHEDVIVEGECNDALYIVLEGTFGIYRKGGETA 80 Query: 341 EKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAG 442 G G FGE+AL+ PR+A+VRA+T G Sbjct: 81 ADHRVAEIGPGQPFGEMALLDGEPRSATVRAETDG 115 >UniRef50_Q00X68 Cluster: Cyclic nucleotide dependent protein kinase; n=3; Eukaryota|Rep: Cyclic nucleotide dependent protein kinase - Ostreococcus tauri Length = 1179 Score = 44.4 bits (100), Expect = 0.002 Identities = 32/104 (30%), Positives = 52/104 (50%), Gaps = 5/104 (4%) Frame = +2 Query: 134 QRARLAEAVRGILLFR-SLDAQQMQQVLDAMFEKRSEPGEYVIRQGD----DGDNFYVIE 298 +R RL + + +FR SLDA+ M ++DA+ E E G ++ D + FYV+ Sbjct: 197 RRCRLTSYLDAVEVFRESLDARTMSMLVDALREVTFESGHVIVSPDDVYEEESSKFYVVI 256 Query: 299 NGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 430 +G + +V DD + V+ FGEL+L++ A V A Sbjct: 257 DG--EAVVYVDDGSKAEVNRLRRGDYFGELSLIHKTSPTAMVIA 298 Score = 39.9 bits (89), Expect = 0.032 Identities = 21/74 (28%), Positives = 39/74 (52%), Gaps = 1/74 (1%) Frame = +2 Query: 86 DDSDEGAPA-VFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIR 262 DD+DE A + ++ +EA+ G+ LFR L + ++ E E G+ ++R Sbjct: 17 DDADENARIRARARRVSEPESASEALDGVALFRELKRDARAALCGSVVECEYERGDVIVR 76 Query: 263 QGDDGDNFYVIENG 304 + + G +FYV+ +G Sbjct: 77 KNEVGTHFYVVAHG 90 >UniRef50_A7SE96 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 174 Score = 44.4 bits (100), Expect = 0.002 Identities = 34/101 (33%), Positives = 50/101 (49%), Gaps = 6/101 (5%) Frame = +2 Query: 176 FRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG------VFDVLVTGDDR 337 F + QQ + + + E +IRQG +NFY I +G +F VTG+ R Sbjct: 51 FGEYPLKMQQQPVKVGWYESFEAKRVIIRQGHPAENFYFILSGTALVTLLFVDPVTGEQR 110 Query: 338 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWGHG 460 V +GS SFGELAL+++ R+A+V + AL G Sbjct: 111 SNTVAVLGKGS-SFGELALLHHKTRSATVLCKEDVALLAVG 150 >UniRef50_Q7V424 Cluster: Possible mechanosensitive ion channel; n=1; Prochlorococcus marinus str. MIT 9313|Rep: Possible mechanosensitive ion channel - Prochlorococcus marinus (strain MIT 9313) Length = 496 Score = 44.0 bits (99), Expect = 0.002 Identities = 29/87 (33%), Positives = 43/87 (49%), Gaps = 1/87 (1%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 352 LF L Q+ + + R GE +IRQG+ GD Y + G +V T + + +K+ Sbjct: 339 LFTDLSQAQLDALAPSTRCVRFAKGETIIRQGESGDCLYQMITGTVEVSQT-NSQGQKIT 397 Query: 353 HTYEGSGS-FGELALMYNMPRAASVRA 430 G FGE+AL PR ++VRA Sbjct: 398 FQKLGQHEIFGEMALCTKQPRNSTVRA 424 >UniRef50_Q6MLN6 Cluster: Putative uncharacterized protein; n=1; Bdellovibrio bacteriovorus|Rep: Putative uncharacterized protein - Bdellovibrio bacteriovorus Length = 400 Score = 44.0 bits (99), Expect = 0.002 Identities = 26/62 (41%), Positives = 37/62 (59%), Gaps = 1/62 (1%) Frame = +2 Query: 248 EYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPRAASV 424 + + +GD GD Y+IE G + +T D E++ T G G FGE+AL+ N R+ASV Sbjct: 14 QIIFSEGDAGDCAYIIEKGRVLIYLTKDK--EEIPLTILGEGEIFGEMALIDNQNRSASV 71 Query: 425 RA 430 RA Sbjct: 72 RA 73 >UniRef50_Q3JAP3 Cluster: Cyclic nucleotide-binding protein; n=1; Nitrosococcus oceani ATCC 19707|Rep: Cyclic nucleotide-binding protein - Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) Length = 257 Score = 44.0 bits (99), Expect = 0.002 Identities = 24/68 (35%), Positives = 35/68 (51%) Frame = +2 Query: 200 MQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF 379 + QVLD + R EPGE V R G+ G + + G+F + G ++VH + SF Sbjct: 47 LAQVLDPIEIHRFEPGEMVCRVGEKGRYLFSVRAGIFKAVRYGQGGEYRIVHLFRNGESF 106 Query: 380 GELALMYN 403 G L L+ N Sbjct: 107 G-LELLTN 113 >UniRef50_Q1GWA6 Cluster: Cyclic nucleotide-binding protein precursor; n=4; Sphingomonadales|Rep: Cyclic nucleotide-binding protein precursor - Sphingopyxis alaskensis (Sphingomonas alaskensis) Length = 811 Score = 44.0 bits (99), Expect = 0.002 Identities = 27/83 (32%), Positives = 48/83 (57%), Gaps = 1/83 (1%) Frame = +2 Query: 185 LDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYE 364 L A+ + V++A +R G+ V+ +G+ GD+ YVI +G ++V D + + Y Sbjct: 478 LTAEDLAPVVEAAEVERVPAGKAVLIEGEQGDDVYVIRSG--SMVVEKDIGGKPIFLRYL 535 Query: 365 GSGS-FGELALMYNMPRAASVRA 430 +GS FGE+ ++ PR A+V+A Sbjct: 536 PAGSFFGEMGVLSGEPRNATVKA 558 >UniRef50_Q0VS63 Cluster: Cyclic nucleotide-binding protein; n=1; Alcanivorax borkumensis SK2|Rep: Cyclic nucleotide-binding protein - Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) Length = 153 Score = 44.0 bits (99), Expect = 0.002 Identities = 25/86 (29%), Positives = 41/86 (47%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 352 LF L ++ + +F R G+ V R+GD D + G D++ + E V+ Sbjct: 13 LFAGLSEDELAILEKLVFVNRVPVGDVVCREGDRSDFVCFVVRGCLDIVKNNEGGGEVVI 72 Query: 353 HTYEGSGSFGELALMYNMPRAASVRA 430 GE+AL+ + PR+A+VRA Sbjct: 73 AHLRPGDCMGEMALVDHEPRSATVRA 98 >UniRef50_Q59V20 Cluster: Putative uncharacterized protein; n=1; Candida albicans|Rep: Putative uncharacterized protein - Candida albicans (Yeast) Length = 721 Score = 44.0 bits (99), Expect = 0.002 Identities = 29/88 (32%), Positives = 44/88 (50%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 352 LF++ +QV + P E++I++GD + Y I G V VT D E Sbjct: 58 LFKNAPTSFHKQVAANLRLIHYRPQEFIIKKGDLSRSMYWILKGT--VSVTSTDGEEVYA 115 Query: 353 HTYEGSGSFGELALMYNMPRAASVRAQT 436 +G FGE+ ++YN PR A+V A+T Sbjct: 116 ELNQGE-FFGEIGILYNRPRTATVIAKT 142 Score = 33.1 bits (72), Expect = 3.7 Identities = 26/111 (23%), Positives = 53/111 (47%), Gaps = 2/111 (1%) Frame = +2 Query: 110 AVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDD-GDNF 286 A+ K + + + + + LF+ L + ++ ++ P EY++R+GD GD + Sbjct: 177 AMQDKKNKEPLSIQSFITNLPLFQFLPPDIIHKLALSVEPLVFSPFEYILRKGDTCGDIY 236 Query: 287 YVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQT 436 ++IE +V V + V ++ SGS FGE++ + + +R T Sbjct: 237 FIIEG---EVEVLNQEGVIEIPLARLSSGSYFGEMSFLNYLQNKPRIRTAT 284 >UniRef50_Q4WI41 Cluster: Cyclic nucleotide-binding domain protein; n=5; Eurotiomycetidae|Rep: Cyclic nucleotide-binding domain protein - Aspergillus fumigatus (Sartorya fumigata) Length = 900 Score = 44.0 bits (99), Expect = 0.002 Identities = 26/97 (26%), Positives = 47/97 (48%) Frame = +2 Query: 146 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 325 L + +R LF+S + +V + + S P +Y++ +GD+ Y + G V T Sbjct: 54 LIDRLRSFPLFQSTPESFLVEVAQHLRPQLSAPNDYILTEGDEAKAIYWLVRGA--VSAT 111 Query: 326 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 D E + E FGE+ ++ + PR A++ A+T Sbjct: 112 SRDG-ESIYADLEPGAFFGEIGVLMDRPRTATIIART 147 >UniRef50_A1CZ15 Cluster: Cyclic nucleotide-binding domain protein; n=22; Pezizomycotina|Rep: Cyclic nucleotide-binding domain protein - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 920 Score = 44.0 bits (99), Expect = 0.002 Identities = 26/97 (26%), Positives = 47/97 (48%) Frame = +2 Query: 146 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 325 L + +R LF+S + +V + + S P +Y++ +GD+ Y + G V T Sbjct: 54 LIDRLRSFPLFQSTPESFLVEVAQHLRPQLSAPNDYILTEGDEAKAIYWLVRGA--VSAT 111 Query: 326 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 D E + E FGE+ ++ + PR A++ A+T Sbjct: 112 SRDG-ESIYADLEPGAFFGEIGVLMDRPRTATIIART 147 >UniRef50_UPI00006CC0E9 Cluster: cation channel family protein; n=1; Tetrahymena thermophila SB210|Rep: cation channel family protein - Tetrahymena thermophila SB210 Length = 1238 Score = 43.6 bits (98), Expect = 0.003 Identities = 23/83 (27%), Positives = 41/83 (49%), Gaps = 5/83 (6%) Frame = +2 Query: 200 MQQVLDAMFEKRSEPGEYVIRQGDDGD-NFYVIENGVFDVLV----TGDDRVEKVVHTYE 364 +++ + + EKR P E + RQ D GD N Y I +G + + G ++ +++ + + Sbjct: 496 LERTVSIIKEKRYYPEEIIFRQNDTGDSNIYFIASGQVQIYIEASYPGGEKKVQILQSLQ 555 Query: 365 GSGSFGELALMYNMPRAASVRAQ 433 SFG + PR +VR Q Sbjct: 556 SGQSFGHYSFFTGQPRMVNVRTQ 578 >UniRef50_Q2S8X4 Cluster: CAMP-binding protein-catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; n=1; Hahella chejuensis KCTC 2396|Rep: CAMP-binding protein-catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase - Hahella chejuensis (strain KCTC 2396) Length = 263 Score = 43.6 bits (98), Expect = 0.003 Identities = 30/89 (33%), Positives = 45/89 (50%) Frame = +2 Query: 233 RSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPR 412 R +PG+ +IRQG++ DN Y + G D V D+ ++V +EG FG +A + N PR Sbjct: 153 RYKPGDVIIRQGEEADNVYTMMKG--DAKVFIDE--QEVGEVHEGE-IFGAIAALTNAPR 207 Query: 413 AASVRAQTAGALWGHGPPHVSFAXCSRAH 499 A+V A + + P F AH Sbjct: 208 NATVVAGNSCTVM--AVPKTQFVSLIHAH 234 >UniRef50_P74736 Cluster: CAMP protein kinase regulatory chain; n=2; Chroococcales|Rep: CAMP protein kinase regulatory chain - Synechocystis sp. (strain PCC 6803) Length = 434 Score = 43.6 bits (98), Expect = 0.003 Identities = 29/93 (31%), Positives = 45/93 (48%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 352 + +L Q+ Q+ + + P E + R+GD GD FY I G DV G V ++ Sbjct: 139 VMNALPEQERHQLAGLLTPHHAYPREVLCREGDQGDYFYFIGGGEADV-YKGTTWVNRLT 197 Query: 353 HTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 FGE++L+ PR+A+V A T L+ Sbjct: 198 ----SGDIFGEMSLLTGEPRSATVVAVTPMELY 226 >UniRef50_Q9X7J4 Cluster: DnrD protein; n=9; Pseudomonas|Rep: DnrD protein - Pseudomonas stutzeri (Pseudomonas perfectomarina) Length = 227 Score = 43.6 bits (98), Expect = 0.003 Identities = 26/94 (27%), Positives = 45/94 (47%), Gaps = 1/94 (1%) Frame = +2 Query: 152 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 331 + +R LF L+ +QM+++L+A + G+ + QG+ NFY + +G V Sbjct: 9 QILRSHHLFEPLNEEQMEELLNASQLLNLDKGDNLFHQGEPAHNFYFVISGAVKVYRLTP 68 Query: 332 DRVEKVVHTYEGSGSFGELALMYNMPR-AASVRA 430 D EKV +F E ++ + P AS +A Sbjct: 69 DGQEKVFEVIGNRQTFAEAMMLMDTPNYVASAQA 102 >UniRef50_Q7D903 Cluster: Cyclic nucleotide-binding protein; n=19; Mycobacterium|Rep: Cyclic nucleotide-binding protein - Mycobacterium tuberculosis Length = 316 Score = 43.6 bits (98), Expect = 0.003 Identities = 24/84 (28%), Positives = 46/84 (54%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 352 +F+ A+ + + ++ R+ G+ ++RQG+ +F +I +G +V GDD V + Sbjct: 3 VFQGCPAEGLVSLAASVQPLRAAAGQVLLRQGEPAVSFLLISSGSAEVSHVGDDGVAIIA 62 Query: 353 HTYEGSGSFGELALMYNMPRAASV 424 G GE+AL+ + PR+A+V Sbjct: 63 RALPGM-IVGEIALLRDSPRSATV 85 >UniRef50_Q13J41 Cluster: Transcriptional regulator, Crp/Fnr family; n=5; Burkholderiaceae|Rep: Transcriptional regulator, Crp/Fnr family - Burkholderia xenovorans (strain LB400) Length = 237 Score = 43.6 bits (98), Expect = 0.003 Identities = 29/107 (27%), Positives = 47/107 (43%) Frame = +2 Query: 143 RLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV 322 +LA + FRS A Q+++A +R G+ + +GD D Y + +G+ + Sbjct: 9 KLAAVLERSAWFRSAPATMQAQLVEAGRLERLAAGQRLFTRGDSDDGLYCVLDGLVRIGA 68 Query: 323 TGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWGHGP 463 E ++ E FGE+AL N PR A+ L+ H P Sbjct: 69 ASSAGKEALLAVIEPVNWFGEIALFDNRPRTHDAYAERDSELF-HVP 114 >UniRef50_A0YCM5 Cluster: CAMP-binding protein-catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; n=2; unclassified Gammaproteobacteria|Rep: CAMP-binding protein-catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase - marine gamma proteobacterium HTCC2143 Length = 216 Score = 43.6 bits (98), Expect = 0.003 Identities = 24/85 (28%), Positives = 43/85 (50%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 352 +F L Q+++ + + + +I + D D+ Y+IE G V + + E ++ Sbjct: 8 IFEGLTPQELEVLASSGVMRTYPKNTVIINENDLADSLYIIETGRVKVYCSDKNGKEFIM 67 Query: 353 HTYEGSGSFGELALMYNMPRAASVR 427 +T FGELAL+ + R+ASVR Sbjct: 68 NTLGAGDYFGELALLDDDRRSASVR 92 >UniRef50_A0LNC0 Cluster: Cyclic nucleotide-binding protein; n=1; Syntrophobacter fumaroxidans MPOB|Rep: Cyclic nucleotide-binding protein - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 171 Score = 43.6 bits (98), Expect = 0.003 Identities = 31/121 (25%), Positives = 61/121 (50%) Frame = +2 Query: 77 PEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYV 256 P E +S E APA + + + + E +R + +F + +++ + + GE++ Sbjct: 4 PTERNS-ECAPASRGRCELEDS--LEILRNVSVFAGIPLPRLKLYAYLSRKMCFQAGEFL 60 Query: 257 IRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 436 QGD GD Y++ +G V+ + ++H ++ FG +AL+ ++ R SVRA T Sbjct: 61 FHQGDSGDRGYIVISGRLQVIRELKEH-SVLLHEFKPGDFFGGMALLSDVNRLFSVRAVT 119 Query: 437 A 439 + Sbjct: 120 S 120 >UniRef50_A0L6N5 Cluster: Cyclic nucleotide-binding; n=1; Magnetococcus sp. MC-1|Rep: Cyclic nucleotide-binding - Magnetococcus sp. (strain MC-1) Length = 729 Score = 43.6 bits (98), Expect = 0.003 Identities = 25/92 (27%), Positives = 46/92 (50%), Gaps = 1/92 (1%) Frame = +2 Query: 170 LLFRSLDAQQMQ-QVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEK 346 LL R + + +M ++L + E + G+ + QG+ D Y+IE+G + + D K Sbjct: 590 LLTRIMGSTEMATRILPYLKELSLKSGDILFEQGEVTDGLYIIESGKIAIYFSHPDGWTK 649 Query: 347 VVHTYEGSGSFGELALMYNMPRAASVRAQTAG 442 V E GE+ L + +PR+A+ + +G Sbjct: 650 QVRILEQGTLVGEMGLYHTLPRSAAAIVEESG 681 >UniRef50_Q24DS4 Cluster: Cation channel family protein; n=1; Tetrahymena thermophila SB210|Rep: Cation channel family protein - Tetrahymena thermophila SB210 Length = 2194 Score = 43.6 bits (98), Expect = 0.003 Identities = 25/95 (26%), Positives = 47/95 (49%), Gaps = 4/95 (4%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDN--FYVIENGVFDVL--VT 325 + I LF+ + ++ ++ M E+ PGE + QGD DN +Y+++ V + + Sbjct: 545 LNNIPLFKHI--KEKDKIAKIMEEQLYSPGEMIFHQGDQDDNSLYYIVKGSVSIIFNPTS 602 Query: 326 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 430 +R K +H + FGE++ + PR S +A Sbjct: 603 NQNREAKQIHLIKKKEYFGEISFINGNPRTFSAKA 637 Score = 32.3 bits (70), Expect = 6.5 Identities = 22/94 (23%), Positives = 42/94 (44%), Gaps = 4/94 (4%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGD-DGDNFYVIENGVFDVLVTGD- 331 + I LF+ + ++ ++ M E PGE + QGD D + Y I G ++ + Sbjct: 1632 LNNIPLFKHI--KEKDKIAKIMEEHLYSPGETIFNQGDLDDSSLYYIVKGSVSIIFNPEN 1689 Query: 332 --DRVEKVVHTYEGSGSFGELALMYNMPRAASVR 427 +R K + + FGE++ + PR + + Sbjct: 1690 NPNREAKQIQLVKKKEYFGEISFISGNPRTFTAK 1723 >UniRef50_Q23EB1 Cluster: Cation channel family protein; n=2; Tetrahymena thermophila SB210|Rep: Cation channel family protein - Tetrahymena thermophila SB210 Length = 1130 Score = 43.6 bits (98), Expect = 0.003 Identities = 24/95 (25%), Positives = 44/95 (46%), Gaps = 2/95 (2%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKV- 349 +F Q + +++ M E PGE + +GD D+ Y+I +G +L + + Sbjct: 609 IFNCFSQQSINKLVFQMKEIIVSPGEVIFSEGDRDDSIYLITSGQIQILQNTAQKSCSIF 668 Query: 350 -VHTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 + T + FGE+A MPR A+ ++ L+ Sbjct: 669 QLKTLSENQIFGEIAFFSQMPRTATAKSLNLSTLY 703 >UniRef50_A0BGA2 Cluster: Chromosome undetermined scaffold_105, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_105, whole genome shotgun sequence - Paramecium tetraurelia Length = 969 Score = 43.6 bits (98), Expect = 0.003 Identities = 21/93 (22%), Positives = 47/93 (50%), Gaps = 1/93 (1%) Frame = +2 Query: 149 AEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGD-DGDNFYVIENGVFDVLVT 325 A+ + I +F+ +++++ M + +P E +++Q D D+ Y+I+ G + T Sbjct: 463 AKYFQKIAVFQKFSQDTQERLIEKMTYQIFQPNEMILKQNSRDDDSLYMIKRGCVKICYT 522 Query: 326 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASV 424 G + + + +FGE++ +PR +SV Sbjct: 523 GINNAQTGIKQLTKFQTFGEVSFFTGLPRTSSV 555 >UniRef50_Q6C384 Cluster: Similar to DEHA0B08261g Debaryomyces hansenii IPF 9819.1; n=1; Yarrowia lipolytica|Rep: Similar to DEHA0B08261g Debaryomyces hansenii IPF 9819.1 - Yarrowia lipolytica (Candida lipolytica) Length = 964 Score = 43.6 bits (98), Expect = 0.003 Identities = 25/65 (38%), Positives = 34/65 (52%) Frame = +2 Query: 242 PGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAAS 421 P EY++ QGD+ Y I G V VT D E V E FGE+ ++++ PR A+ Sbjct: 127 PQEYIVTQGDEAKAMYWILKG--QVNVTSRDG-ESVYAELEAGSFFGEIGILFDRPRTAT 183 Query: 422 VRAQT 436 V A T Sbjct: 184 VLAST 188 Score = 37.5 bits (83), Expect = 0.17 Identities = 22/88 (25%), Positives = 44/88 (50%), Gaps = 2/88 (2%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD-DRVEKV 349 LFR + + ++ A+ + EP +Y+I+Q G Y + +G+ +V+ + + Sbjct: 256 LFRHIPETIVHKLALAVEPRTYEPFQYIIKQDTIGQEIYFLTSGIVEVIDEREIGTAAHI 315 Query: 350 VHTYEGSGSFGELALMYNMP-RAASVRA 430 + FGE+A + + P R AS+R+ Sbjct: 316 IARLTKGSYFGEMAFLSSNPVRTASIRS 343 >UniRef50_A3LZH5 Cluster: Leucine rich repeat protein, contains F-box; n=1; Pichia stipitis|Rep: Leucine rich repeat protein, contains F-box - Pichia stipitis (Yeast) Length = 868 Score = 43.6 bits (98), Expect = 0.003 Identities = 24/65 (36%), Positives = 35/65 (53%) Frame = +2 Query: 242 PGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAAS 421 P EY+I++GD + Y I G V VT D E + FGE+ +++N PR A+ Sbjct: 49 PQEYIIKKGDPSKSMYWILKGT--VSVTSTDG-ESIYAELAAGSFFGEIGILFNRPRTAT 105 Query: 422 VRAQT 436 V A+T Sbjct: 106 VVART 110 Score = 32.7 bits (71), Expect = 4.9 Identities = 22/108 (20%), Positives = 51/108 (47%), Gaps = 8/108 (7%) Frame = +2 Query: 98 EGAPAVFPKSDAQRAR----LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQ 265 E AP++ P + A + + ++ + +F++L + + Q+ + EY+I + Sbjct: 165 ESAPSLPPIRNGINANATISIQDFIKNLPIFQNLPSTIIHQLALGVEPINFNAFEYIIHK 224 Query: 266 GDDGDNFYVIENGVFDVLVTGDDR----VEKVVHTYEGSGSFGELALM 397 GD + Y I NG +V+ ++ +E+++ FGE++ + Sbjct: 225 GDTNSDIYFIINGEVEVIDYSRNQEGAHIERILARLSSGSYFGEMSFL 272 >UniRef50_UPI0000F1F638 Cluster: PREDICTED: similar to putative cNMP-gated potassium channel; n=2; Danio rerio|Rep: PREDICTED: similar to putative cNMP-gated potassium channel - Danio rerio Length = 1716 Score = 43.2 bits (97), Expect = 0.003 Identities = 21/68 (30%), Positives = 37/68 (54%) Frame = +2 Query: 248 EYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVR 427 + + ++GD G Y +E G +VL + KV+ FGE +L+++ PRAA++R Sbjct: 1099 DVIYKKGDCGSEVYFVEKGEVEVLSNNES---KVLFKLSAGQYFGERSLLFHEPRAATIR 1155 Query: 428 AQTAGALW 451 A T ++ Sbjct: 1156 AATNSEMY 1163 Score = 36.7 bits (81), Expect = 0.30 Identities = 20/65 (30%), Positives = 32/65 (49%) Frame = +2 Query: 242 PGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAAS 421 PG+ + + G+ N Y I++G V E + T FGE+ L+Y +PR + Sbjct: 171 PGQTLAKAGEINQNLYYIKHGHVQVF---SQNPEVEIATLLPGTLFGEVHLLYEIPRNVT 227 Query: 422 VRAQT 436 +RA T Sbjct: 228 IRAST 232 >UniRef50_UPI00006D001F Cluster: cyclic nucleotide-binding domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 705 Score = 43.2 bits (97), Expect = 0.003 Identities = 23/89 (25%), Positives = 47/89 (52%), Gaps = 2/89 (2%) Frame = +2 Query: 170 LLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGD-NFYVIENGVFDVLVTG-DDRVE 343 L + + +++++ M E P E + +Q + D + Y I++G+ ++ V+ ++ E Sbjct: 120 LFIANFSQKVIKEIIFLMEEIIVAPNEIIFKQCEAEDQSIYFIQSGLVEIFVSNTQEQSE 179 Query: 344 KVVHTYEGSGSFGELALMYNMPRAASVRA 430 KV+ E FGE++ +PR AS R+ Sbjct: 180 KVITQLEQDSMFGEISFFSGLPRTASARS 208 >UniRef50_Q97TL8 Cluster: CRP (Cyclic AMP receptor protein) regulatory protein; n=1; Clostridium acetobutylicum|Rep: CRP (Cyclic AMP receptor protein) regulatory protein - Clostridium acetobutylicum Length = 188 Score = 43.2 bits (97), Expect = 0.003 Identities = 19/60 (31%), Positives = 31/60 (51%) Frame = +2 Query: 248 EYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVR 427 + + RQG+ NFY ++ G V V D +EK++ Y+ FGE + PR +S + Sbjct: 6 QIIYRQGEIAKNFYYLKEGRVQVFVNSTDGLEKILAIYKKGEIFGEASFFDGFPRMSSAK 65 >UniRef50_Q746U7 Cluster: Transcriptional regulator, Crp/Fnr family; n=7; Desulfuromonadales|Rep: Transcriptional regulator, Crp/Fnr family - Geobacter sulfurreducens Length = 241 Score = 43.2 bits (97), Expect = 0.003 Identities = 26/99 (26%), Positives = 41/99 (41%) Frame = +2 Query: 146 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 325 + + +R LLF LD + +V + GE V +G+ + FY++ G + Sbjct: 14 IRDILRKSLLFSGLDENHLAEVAAIAARRPFARGETVFAEGEPANGFYLLAQGSMKLCKV 73 Query: 326 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAG 442 D EKV+H +F E A + A RA G Sbjct: 74 SPDGKEKVLHFVHPGETFAEAAFFGDGKYPAEARAVEKG 112 >UniRef50_Q31NU6 Cluster: Cyclic nucleotide-binding domain (CNMP-BD) protein; n=2; Synechococcus elongatus|Rep: Cyclic nucleotide-binding domain (CNMP-BD) protein - Synechococcus sp. (strain PCC 7942) (Anacystis nidulans R2) Length = 231 Score = 43.2 bits (97), Expect = 0.003 Identities = 28/97 (28%), Positives = 45/97 (46%) Frame = +2 Query: 149 AEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTG 328 + AV+ LF +L A+Q+ ++ A + G+ V+ + D D +Y+I G+ V + Sbjct: 4 SSAVQQHPLFANLSAEQLARLTQASRPRHYPAGQAVLLEHDWSDGYYLITAGIAKVAIAS 63 Query: 329 DDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTA 439 E +V FGEL + R A V A TA Sbjct: 64 SGGDEVIVGLLGAGELFGELRALGFEARTAEVTALTA 100 >UniRef50_A0XC88 Cluster: Cyclic nucleotide-binding; n=1; Dinoroseobacter shibae DFL 12|Rep: Cyclic nucleotide-binding - Dinoroseobacter shibae DFL 12 Length = 733 Score = 43.2 bits (97), Expect = 0.003 Identities = 28/89 (31%), Positives = 45/89 (50%), Gaps = 1/89 (1%) Frame = +2 Query: 188 DAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV-TGDDRVEKVVHTYE 364 DA Q+VL M + G+ ++ GD + ++E G VL T D R+ ++ Sbjct: 602 DAALAQRVLSMMTREEVAAGQRLMACGDRDTDVILVERGQLAVLAPTPDGRMRRIQSLRP 661 Query: 365 GSGSFGELALMYNMPRAASVRAQTAGALW 451 G+ GE+A +PRAA V A+TA ++ Sbjct: 662 GA-LIGEIASYAGLPRAADVIAETAATVY 689 >UniRef50_Q236Y9 Cluster: Cyclic nucleotide-binding domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 983 Score = 43.2 bits (97), Expect = 0.003 Identities = 23/79 (29%), Positives = 40/79 (50%), Gaps = 1/79 (1%) Frame = +2 Query: 203 QQVLDAMFEKRSEPGEYVIRQGDDGD-NFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF 379 +++ M E PGEY+ ++ D D + Y+I G D++ T + R E ++ T + F Sbjct: 321 KEIAIIMEEVIFSPGEYIYQKDDVDDCSLYLIVKGQVDIVFTSEKRGESIIQTLDKLKYF 380 Query: 380 GELALMYNMPRAASVRAQT 436 GE + + R S +A T Sbjct: 381 GEQSFISGFQRELSAKAAT 399 >UniRef50_A0DXZ3 Cluster: Chromosome undetermined scaffold_69, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_69, whole genome shotgun sequence - Paramecium tetraurelia Length = 945 Score = 43.2 bits (97), Expect = 0.003 Identities = 38/106 (35%), Positives = 53/106 (50%), Gaps = 10/106 (9%) Frame = +2 Query: 146 LAEAVRGILLFRSLDAQQMQQVLDAMFE---KRSEPGEYVIRQGDDGDNFYVI---ENGV 307 L + V I F++L +Q VL M K + E + GD G FY+I GV Sbjct: 458 LLQLVEAIAFFKNLQSQNPDIVLRCMSVLSYKTVKKEEILFHVGDQGSLFYIILKGSVGV 517 Query: 308 FDVLVTGDD--RVE-KVVHTYEGSGSFGELALMY-NMPRAASVRAQ 433 F +L + DD R E K V+ + SFGELAL+ N R A++ A+ Sbjct: 518 FILLPSPDDSKRFELKEVNILKAGNSFGELALLNDNAKRTATIIAK 563 >UniRef50_Q1D9D3 Cluster: Cyclic nucleotide-binding domain protein; n=2; Cystobacterineae|Rep: Cyclic nucleotide-binding domain protein - Myxococcus xanthus (strain DK 1622) Length = 449 Score = 42.7 bits (96), Expect = 0.005 Identities = 30/87 (34%), Positives = 43/87 (49%), Gaps = 1/87 (1%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 352 LF LD ++ M +R +P E V R+G+ D+ YV+ G + VT E Sbjct: 173 LFAELDRDAFVDLVRLMAWRRVKPEEAVSREGEPADSLYVLVAGKAE--VTRQMEGEART 230 Query: 353 HTYEGSGS-FGELALMYNMPRAASVRA 430 + G GS FGE+AL+ P A+V A Sbjct: 231 LGFLGGGSIFGEIALLTGAPPTATVSA 257 >UniRef50_A7BRE2 Cluster: Protein kinase, cGMP-dependent, type I; n=1; Beggiatoa sp. PS|Rep: Protein kinase, cGMP-dependent, type I - Beggiatoa sp. PS Length = 200 Score = 42.7 bits (96), Expect = 0.005 Identities = 29/82 (35%), Positives = 43/82 (52%), Gaps = 2/82 (2%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD-- 331 +R L F+ L + + M + G+ +IRQG+ GD FY+I++G +V V D Sbjct: 108 IRHSLAFQRLPLECVIGAFKCMKTVNVKQGDEIIRQGEQGDKFYLIKSGRAEVWVLEDFE 167 Query: 332 DRVEKVVHTYEGSGSFGELALM 397 D EK V + SFGE AL+ Sbjct: 168 DEPEK-VGILGTNDSFGEQALL 188 >UniRef50_A5GPF7 Cluster: Conserved hyppthetical protein; n=1; Synechococcus sp. WH 7803|Rep: Conserved hyppthetical protein - Synechococcus sp. (strain WH7803) Length = 465 Score = 42.7 bits (96), Expect = 0.005 Identities = 27/89 (30%), Positives = 45/89 (50%), Gaps = 2/89 (2%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV--TGDDRVEK 346 LF SL Q++ ++ E ++R+GD GD+ YV+ G V V +G + + Sbjct: 309 LFASLTDAQIRDIVVHDAALAFGDSEVIVREGDVGDSMYVVLEGTCSVQVKASGGPQEQI 368 Query: 347 VVHTYEGSGSFGELALMYNMPRAASVRAQ 433 ++ FGE+A + + PR ASV A+ Sbjct: 369 LLAELRQGAVFGEMAALTDEPRKASVLAK 397 >UniRef50_A1ZG79 Cluster: Transporter, small conductance mechanosensitive ion channel (MscS) family; n=1; Microscilla marina ATCC 23134|Rep: Transporter, small conductance mechanosensitive ion channel (MscS) family - Microscilla marina ATCC 23134 Length = 487 Score = 42.7 bits (96), Expect = 0.005 Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 1/99 (1%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV-TGDD 334 +R + LF+ L ++ + ++ GE VIR GD+GD+ +V+ G+ +V V D Sbjct: 323 LRKVELFKPLGESELAVLGTSIKRIEFTKGEVVIRTGDEGDSMFVVLEGLLEVFVDVFGD 382 Query: 335 RVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALW 451 E V + GE +L+ R+A+ +A T L+ Sbjct: 383 GDELRVGLVKPGQFLGEKSLLTGASRSATAKAATNAILY 421 >UniRef50_A7RK87 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 573 Score = 42.7 bits (96), Expect = 0.005 Identities = 25/102 (24%), Positives = 51/102 (50%), Gaps = 1/102 (0%) Frame = +2 Query: 122 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 301 +++ Q A++ ++R I F + ++++ + + ++RQG FY + + Sbjct: 165 RTEQQCAKVLFSLRSIRAFAEYPQRIQHKLINVGWYESHSSKRAILRQGQIPQAFYFVLS 224 Query: 302 GVFDVLVTGD-DRVEKVVHTYEGSGSFGELALMYNMPRAASV 424 G V V G+ D + VH SFGELA++++ R ++V Sbjct: 225 GSAVVTVLGEHDTFARTVHFLRRGDSFGELAILHDTQRQSTV 266 >UniRef50_Q03611 Cluster: Cyclic nucleotide-gated cation channel; n=2; Caenorhabditis|Rep: Cyclic nucleotide-gated cation channel - Caenorhabditis elegans Length = 733 Score = 42.7 bits (96), Expect = 0.005 Identities = 21/82 (25%), Positives = 46/82 (56%) Frame = +2 Query: 152 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 331 E +R + +F+ +A + +++ + + PG+++ ++GD G Y+++ G V+ D Sbjct: 486 ETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVV---D 542 Query: 332 DRVEKVVHTYEGSGSFGELALM 397 D +KV T + FGEL+++ Sbjct: 543 DDGKKVFVTLQEGSVFGELSIL 564 >UniRef50_Q9NQW8 Cluster: Cyclic nucleotide-gated cation channel beta 3; n=21; Tetrapoda|Rep: Cyclic nucleotide-gated cation channel beta 3 - Homo sapiens (Human) Length = 809 Score = 42.7 bits (96), Expect = 0.005 Identities = 23/75 (30%), Positives = 41/75 (54%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 352 LF+ D Q + +L + PG++V ++G+ G Y+I++G +V V G KV+ Sbjct: 524 LFKGCDTQMIYDMLLRLKSVLYLPGDFVCKKGEIGKEMYIIKHG--EVQVLGGPDGTKVL 581 Query: 353 HTYEGSGSFGELALM 397 T + FGE++L+ Sbjct: 582 VTLKAGSVFGEISLL 596 >UniRef50_UPI000155D050 Cluster: PREDICTED: similar to Cyclic nucleotide gated channel alpha 2; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to Cyclic nucleotide gated channel alpha 2 - Ornithorhynchus anatinus Length = 613 Score = 42.3 bits (95), Expect = 0.006 Identities = 22/80 (27%), Positives = 45/80 (56%) Frame = +2 Query: 158 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 337 ++ + +F+ +A + +++ + + PG+Y+ R+GD G Y+I+ G + V GDD Sbjct: 398 LKKVRIFQDCEAGLLVELVLKLQPQVFSPGDYICRKGDVGKEMYIIKEG--KLAVVGDDG 455 Query: 338 VEKVVHTYEGSGSFGELALM 397 V + GS FGE++++ Sbjct: 456 VTQYALLLAGS-CFGEISIL 474 >UniRef50_Q5NXU3 Cluster: Catabolite gene activator; n=3; Rhodocyclaceae|Rep: Catabolite gene activator - Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) Length = 223 Score = 42.3 bits (95), Expect = 0.006 Identities = 28/93 (30%), Positives = 47/93 (50%), Gaps = 1/93 (1%) Frame = +2 Query: 155 AVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDD 334 A++ LF+ L + V +R G+ V+ G+ D Y++ G V+V+ +D Sbjct: 11 ALKTFSLFQGLSDDTLATVSRLAMMRRIPRGQSVVHAGERCDFVYLVLTGSLKVVVSDED 70 Query: 335 RVEKVVHTYEGSGS-FGELALMYNMPRAASVRA 430 E V+ T G G FGE+++ PR+A+V A Sbjct: 71 GRE-VILTILGQGELFGEMSMFGEQPRSATVVA 102 >UniRef50_Q55427 Cluster: Slr0842 protein; n=1; Synechocystis sp. PCC 6803|Rep: Slr0842 protein - Synechocystis sp. (strain PCC 6803) Length = 404 Score = 42.3 bits (95), Expect = 0.006 Identities = 28/71 (39%), Positives = 40/71 (56%), Gaps = 2/71 (2%) Frame = +2 Query: 230 KRSEPGEYVIRQGDDGDNFYVIENGVFDVL--VTGDDRVEKVVHTYEGSGSFGELALMYN 403 +R G+ + +GD G+ Y+IE G ++ + GD RV V+ GS FGELAL+ Sbjct: 11 RRYRAGDPIFSEGDQGNFAYIIEEGQVEIWTELNGDRRVLNVLQP--GS-LFGELALVDA 67 Query: 404 MPRAASVRAQT 436 PR+AS A T Sbjct: 68 KPRSASASALT 78 >UniRef50_Q1GTY7 Cluster: Transcriptional regulator, Crp/Fnr family; n=3; Sphingomonadaceae|Rep: Transcriptional regulator, Crp/Fnr family - Sphingopyxis alaskensis (Sphingomonas alaskensis) Length = 227 Score = 42.3 bits (95), Expect = 0.006 Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 1/103 (0%) Frame = +2 Query: 140 ARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDV- 316 ARLAE +F L + ++ + G+ ++ QGD GD ++ G V Sbjct: 4 ARLAELQSPDSIFSGLSVEDWAEITRRAVQVNFAKGKELLVQGDPGDMMLILTEGTARVS 63 Query: 317 LVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGA 445 ++T R E V+ E GE+AL+ R ASV A +AG+ Sbjct: 64 MLTAGGR-EIVLAYAEPGAVLGEIALLDGGERTASVTATSAGS 105 >UniRef50_A4TW60 Cluster: cAMP-binding protein-catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; n=3; Magnetospirillum|Rep: cAMP-binding protein-catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase - Magnetospirillum gryphiswaldense Length = 115 Score = 42.3 bits (95), Expect = 0.006 Identities = 26/76 (34%), Positives = 42/76 (55%), Gaps = 1/76 (1%) Frame = +2 Query: 212 LDAMFEKRSEP-GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGEL 388 ++ + E+R P GE + R+GD G Y+I+ G + L G ++ + + FGE+ Sbjct: 3 INNVLERRFFPAGETIFREGDTGSVAYIIQTGTVE-LSCG----RLMIAELQDNAIFGEM 57 Query: 389 ALMYNMPRAASVRAQT 436 AL+ PR A+ RAQT Sbjct: 58 ALIDGAPRMATARAQT 73 >UniRef50_Q23EB3 Cluster: Cyclic nucleotide-binding domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 948 Score = 42.3 bits (95), Expect = 0.006 Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 2/87 (2%) Frame = +2 Query: 173 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL--VTGDDRVEK 346 +F Q + +++ M E PGE + +GD D+ Y+I +G ++L + + Sbjct: 442 IFNCFSQQSINKLVFFMKEIILSPGEVIFSEGDIDDSIYLINSGQIEILRNTAHKNCLSF 501 Query: 347 VVHTYEGSGSFGELALMYNMPRAASVR 427 + T + FGELA MPR A+ + Sbjct: 502 QLKTLSENQIFGELAFFSQMPRTATAK 528 >UniRef50_Q23AA4 Cluster: Cation channel family protein; n=1; Tetrahymena thermophila SB210|Rep: Cation channel family protein - Tetrahymena thermophila SB210 Length = 1345 Score = 42.3 bits (95), Expect = 0.006 Identities = 21/86 (24%), Positives = 44/86 (51%), Gaps = 1/86 (1%) Frame = +2 Query: 179 RSLDAQQMQQVLDAMFEKRSEPGEYVIRQG-DDGDNFYVIENGVFDVLVTGDDRVEKVVH 355 R+ M+Q++ + E + P ++ ++G D + Y IENG +VL+ D+ ++ + Sbjct: 548 RNFSKSTMEQIIPLIQEMKYTPETFICQEGIQDDASIYFIENGSVEVLLQVKDKKQRSLF 607 Query: 356 TYEGSGSFGELALMYNMPRAASVRAQ 433 T + SFG + R ++R++ Sbjct: 608 TLKKGESFGAHTFFTGLSRVNNIRSK 633 >UniRef50_A7SKJ9 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1023 Score = 42.3 bits (95), Expect = 0.006 Identities = 22/66 (33%), Positives = 35/66 (53%) Frame = +2 Query: 239 EPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAA 418 +PG+Y++ GD G Y I G ++L + V+ T FGE+ L+Y R A Sbjct: 45 KPGDYIVYAGDMGREMYCIRRGQVNILCE-----DNVIGTLGPGSFFGEIGLIYGESRFA 99 Query: 419 SVRAQT 436 +V+A+T Sbjct: 100 TVQAKT 105 Score = 31.9 bits (69), Expect = 8.6 Identities = 19/65 (29%), Positives = 36/65 (55%), Gaps = 1/65 (1%) Frame = +2 Query: 245 GEYVIRQGDDGDNFYVIENGVFDVLVTGD-DRVEKVVHTYEGSGSFGELALMYNMPRAAS 421 GEY+IR+GD G +++ G ++ + D +++E++V + + + L+ P S Sbjct: 920 GEYIIRKGDIGQQLIILKRGTAAIVKSEDPEKLEEMV----VNSFYSQRYLLLTGPYLES 975 Query: 422 VRAQT 436 VRA T Sbjct: 976 VRAIT 980 >UniRef50_A0E9X9 Cluster: Chromosome undetermined scaffold_85, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_85, whole genome shotgun sequence - Paramecium tetraurelia Length = 340 Score = 42.3 bits (95), Expect = 0.006 Identities = 24/83 (28%), Positives = 45/83 (54%), Gaps = 1/83 (1%) Frame = +2 Query: 179 RSLDAQQMQQVLDAMFE-KRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVH 355 R + + + QV+ + + ++ + + + GD G+ FYVI G+ V V +D++ + Sbjct: 11 RIIVGEDLYQVIKSKMQIEQYSVNDVLTKIGDKGNKFYVILQGLVGVFVRNEDQLTMINV 70 Query: 356 TYEGSGSFGELALMYNMPRAASV 424 EG G GEL++M N R A++ Sbjct: 71 CREGEG-MGELSIMSNKSRMATL 92 >UniRef50_A0E001 Cluster: Chromosome undetermined scaffold_70, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_70, whole genome shotgun sequence - Paramecium tetraurelia Length = 467 Score = 42.3 bits (95), Expect = 0.006 Identities = 30/80 (37%), Positives = 42/80 (52%), Gaps = 16/80 (20%) Frame = +2 Query: 245 GEYVIRQGDDGDNFYVIENG---VFDVLVTGD-------------DRVEKVVHTYEGSGS 376 GE + R+GD GD FY+I G V+ V + D+ K+ H EG + Sbjct: 67 GEIICREGDKGDKFYIILQGNVSVYRKNVNSNYEPNSVLSEQIFMDQNVKIGHLKEGE-T 125 Query: 377 FGELALMYNMPRAASVRAQT 436 FGELAL N PR A+++AQ+ Sbjct: 126 FGELALSLNKPRFATIKAQS 145 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 552,875,194 Number of Sequences: 1657284 Number of extensions: 12008671 Number of successful extensions: 54491 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 50405 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 54207 length of database: 575,637,011 effective HSP length: 95 effective length of database: 418,195,031 effective search space used: 30528237263 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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