BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= epV30235 (516 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q7PPI8 Cluster: ENSANGP00000022232; n=3; Endopterygota|... 239 3e-62 UniRef50_P81900 Cluster: cAMP-dependent protein kinase type II r... 232 3e-60 UniRef50_Q5DI18 Cluster: SJCHGC02266 protein; n=1; Schistosoma j... 192 5e-48 UniRef50_P31323 Cluster: cAMP-dependent protein kinase type II-b... 189 4e-47 UniRef50_Q4RSC3 Cluster: Chromosome 13 SCAF15000, whole genome s... 173 2e-42 UniRef50_P31320 Cluster: cAMP-dependent protein kinase regulator... 148 6e-35 UniRef50_A7RGJ3 Cluster: Predicted protein; n=1; Nematostella ve... 139 4e-32 UniRef50_A7S513 Cluster: Predicted protein; n=1; Nematostella ve... 132 5e-30 UniRef50_A6SCU8 Cluster: Putative uncharacterized protein; n=2; ... 132 6e-30 UniRef50_Q5H7P2 Cluster: CAMP-dependent protein kinase regulator... 131 8e-30 UniRef50_Q86ZN7 Cluster: cAMP-dependent protein kinase regulator... 130 2e-29 UniRef50_P10644 Cluster: cAMP-dependent protein kinase type I-al... 126 2e-28 UniRef50_Q4TGP1 Cluster: Chromosome undetermined SCAF3574, whole... 124 1e-27 UniRef50_P07278 Cluster: cAMP-dependent protein kinase regulator... 121 9e-27 UniRef50_Q9HEW1 Cluster: cAMP-dependent protein kinase regulator... 121 9e-27 UniRef50_Q9HFV9 Cluster: CAMP dependent protein kinase regulator... 120 2e-26 UniRef50_Q240X5 Cluster: Cyclic nucleotide-binding domain contai... 115 6e-25 UniRef50_Q5DAR5 Cluster: SJCHGC05163 protein; n=1; Schistosoma j... 113 2e-24 UniRef50_Q9BMY7 Cluster: CAMP-dependent protein kinase regulator... 111 7e-24 UniRef50_Q22NC5 Cluster: Cyclic nucleotide-binding domain contai... 111 7e-24 UniRef50_A0DZ01 Cluster: Chromosome undetermined scaffold_7, who... 111 9e-24 UniRef50_Q7KQK0 Cluster: CAMP-dependent protein kinase regulator... 109 3e-23 UniRef50_Q3SED2 Cluster: CAMP-dependent protein kinase, regulato... 109 4e-23 UniRef50_UPI0001509E09 Cluster: cyclic nucleotide-binding domain... 108 8e-23 UniRef50_P49605 Cluster: cAMP-dependent protein kinase regulator... 108 8e-23 UniRef50_P05987 Cluster: cAMP-dependent protein kinase regulator... 107 2e-22 UniRef50_Q6C2X0 Cluster: cAMP-dependent protein kinase regulator... 105 6e-22 UniRef50_Q9XTM6 Cluster: CAMP-dependent protein kinase regulator... 104 1e-21 UniRef50_A0CJF2 Cluster: Chromosome undetermined scaffold_2, who... 104 1e-21 UniRef50_A0BRC9 Cluster: Chromosome undetermined scaffold_122, w... 104 1e-21 UniRef50_Q8TF77 Cluster: cAMP-dependent protein kinase regulator... 104 1e-21 UniRef50_A0BNE3 Cluster: Chromosome undetermined scaffold_118, w... 103 2e-21 UniRef50_A2R984 Cluster: Catalytic activity: ATP + a protein <=>... 103 2e-21 UniRef50_Q4UEK0 Cluster: CAMP-dependent protein kinase regulator... 101 7e-21 UniRef50_A3FPL6 Cluster: CAMP-dependent protein kinase regulator... 100 2e-20 UniRef50_P36600 Cluster: cAMP-dependent protein kinase regulator... 99 5e-20 UniRef50_A7AU83 Cluster: cAMP-dependent protein kinase regulator... 99 7e-20 UniRef50_Q33DX2 Cluster: Putative cyclic AMP-dependent protein k... 69 2e-19 UniRef50_A0CMC2 Cluster: Chromosome undetermined scaffold_21, wh... 95 8e-19 UniRef50_UPI000065ED67 Cluster: cAMP-dependent protein kinase ty... 88 1e-16 UniRef50_UPI0000D562F1 Cluster: PREDICTED: similar to CG3324-PA;... 87 3e-16 UniRef50_Q8MQE4 Cluster: Putative uncharacterized protein; n=5; ... 85 1e-15 UniRef50_Q3SEP0 Cluster: CGMP-dependent protein kinase 8-2; n=8;... 84 2e-15 UniRef50_A0E3G7 Cluster: Chromosome undetermined scaffold_76, wh... 81 1e-14 UniRef50_Q13237 Cluster: cGMP-dependent protein kinase 2; n=23; ... 81 1e-14 UniRef50_Q03042 Cluster: cGMP-dependent protein kinase, isozyme ... 81 2e-14 UniRef50_Q16JU3 Cluster: Cgmp-dependent protein kinase; n=2; End... 78 1e-13 UniRef50_UPI0000DB6E55 Cluster: PREDICTED: similar to cGMP-depen... 77 2e-13 UniRef50_Q22SE3 Cluster: Cyclic nucleotide-binding domain contai... 76 4e-13 UniRef50_UPI0000519F68 Cluster: PREDICTED: similar to cGMP-depen... 76 6e-13 UniRef50_Q22RR1 Cluster: Protein kinase domain containing protei... 76 6e-13 UniRef50_Q9FXQ0 Cluster: Cyclic nucreotide dependent protein kin... 75 7e-13 UniRef50_Q234E6 Cluster: Protein kinase domain containing protei... 75 7e-13 UniRef50_A2EKL9 Cluster: Cyclic nucleotide-binding domain contai... 75 7e-13 UniRef50_A0D9C4 Cluster: Chromosome undetermined scaffold_42, wh... 75 1e-12 UniRef50_A0DCJ0 Cluster: Chromosome undetermined scaffold_45, wh... 73 3e-12 UniRef50_Q6P5T7 Cluster: PRKG1 protein; n=14; Euteleostomi|Rep: ... 73 3e-12 UniRef50_P14619 Cluster: cGMP-dependent protein kinase 1, beta i... 73 3e-12 UniRef50_Q31QH3 Cluster: Cyclic nucleotide-binding; n=2; Synecho... 73 4e-12 UniRef50_Q5RGL5 Cluster: Novel protein similar to vertebrate pro... 73 5e-12 UniRef50_Q8MMZ4 Cluster: CGMP-dependent protein kinase; n=14; Ap... 72 9e-12 UniRef50_Q5CWD4 Cluster: Cyclic nucleotide (CGMP)-dependent prot... 72 9e-12 UniRef50_A7PEK0 Cluster: Chromosome chr11 scaffold_13, whole gen... 71 2e-11 UniRef50_Q9VL34 Cluster: CG4839-PA, isoform A; n=2; Sophophora|R... 69 5e-11 UniRef50_O76360 Cluster: Egg laying defective protein 4, isoform... 69 6e-11 UniRef50_O17474 Cluster: Cyclic GMP-dependent protein kinase; n=... 69 6e-11 UniRef50_A7C1J1 Cluster: Protein kinase, cGMP-dependent, type I;... 69 8e-11 UniRef50_Q4QGD8 Cluster: Protein kinase A regulatory subunit, pu... 69 8e-11 UniRef50_Q23DN8 Cluster: Cyclic nucleotide-binding domain contai... 68 1e-10 UniRef50_Q4QF64 Cluster: Protein kinase, putative; n=2; Leishman... 68 1e-10 UniRef50_A0BE58 Cluster: Chromosome undetermined scaffold_101, w... 67 3e-10 UniRef50_A4S6U9 Cluster: Predicted protein; n=2; Ostreococcus|Re... 66 4e-10 UniRef50_Q01E02 Cluster: CGMP-dependent protein kinase, putative... 61 5e-10 UniRef50_Q8MMZ5 Cluster: CGMP-dependent protein kinase; n=2; Eim... 66 6e-10 UniRef50_Q4Q2R2 Cluster: Regulatory subunit of protein kinase a-... 65 8e-10 UniRef50_A0E0G1 Cluster: Chromosome undetermined scaffold_71, wh... 64 2e-09 UniRef50_Q2HGG6 Cluster: Putative uncharacterized protein; n=1; ... 64 2e-09 UniRef50_A0YP22 Cluster: Putative uncharacterized protein; n=1; ... 63 3e-09 UniRef50_Q4CSS9 Cluster: Protein kinase, putative; n=2; Trypanos... 62 6e-09 UniRef50_Q0LLK2 Cluster: Stage II sporulation E; n=1; Herpetosip... 62 7e-09 UniRef50_UPI0000660D74 Cluster: Homolog of Homo sapiens "cGMP-de... 62 1e-08 UniRef50_Q8DKN0 Cluster: Tlr0829 protein; n=1; Synechococcus elo... 62 1e-08 UniRef50_A5GVU5 Cluster: ABC-type multidrug transport system, AT... 62 1e-08 UniRef50_A3IKE0 Cluster: Putative uncharacterized protein; n=1; ... 62 1e-08 UniRef50_Q4SL71 Cluster: Chromosome 17 SCAF14563, whole genome s... 59 1e-08 UniRef50_Q8SRB5 Cluster: CAMP-DEPENDENT PROTEIN KINASE TYPE 1 RE... 61 1e-08 UniRef50_Q1D8K7 Cluster: Mechanosensitive ion channel/cyclic nuc... 61 2e-08 UniRef50_A4TWF8 Cluster: Na+/H+ Antiporter; n=1; Magnetospirillu... 61 2e-08 UniRef50_Q9M8S6 Cluster: Potassium channel SKOR (Stelar K(+) out... 59 5e-08 UniRef50_Q8CXT1 Cluster: CAMP-dependent protein kinase regulator... 59 7e-08 UniRef50_Q2VWB6 Cluster: CAMP-dependent protein kinase A regulat... 59 7e-08 UniRef50_Q5QFC4 Cluster: EnvDll2-01; n=1; Oikopleura dioica|Rep:... 58 9e-08 UniRef50_A7C147 Cluster: cGMP-dependent protein kinase type I; n... 58 1e-07 UniRef50_A3YU60 Cluster: Putative glutaminase; n=1; Synechococcu... 58 2e-07 UniRef50_Q10V66 Cluster: Cyclic nucleotide-binding protein; n=2;... 57 2e-07 UniRef50_Q9Y3Q4 Cluster: Potassium/sodium hyperpolarization-acti... 57 2e-07 UniRef50_Q4S874 Cluster: Chromosome 5 SCAF14709, whole genome sh... 57 3e-07 UniRef50_Q3W7N0 Cluster: Cyclic nucleotide-binding domain:Peptid... 57 3e-07 UniRef50_Q0VQV6 Cluster: Cyclic nucleotide-binding domain protei... 57 3e-07 UniRef50_UPI0000EC9F34 Cluster: UPI0000EC9F34 related cluster; n... 56 4e-07 UniRef50_Q6WL05 Cluster: Hyperpolarization-activated ion channel... 56 4e-07 UniRef50_A5G0B9 Cluster: Putative transcriptional regulator, Crp... 56 5e-07 UniRef50_A0LNC0 Cluster: Cyclic nucleotide-binding protein; n=1;... 56 5e-07 UniRef50_Q23EB7 Cluster: Cyclic nucleotide-binding domain contai... 56 5e-07 UniRef50_Q2LV90 Cluster: CAMP-dependent transcriptional regulato... 56 6e-07 UniRef50_Q0F2T2 Cluster: Glucose-6-phosphate 1-dehydrogenase; n=... 56 6e-07 UniRef50_Q08V69 Cluster: PKA regulatory subunit-like protein; n=... 56 6e-07 UniRef50_A7BXC8 Cluster: MscS Mechanosensitive ion channel; n=1;... 56 6e-07 UniRef50_Q2RX44 Cluster: Cyclic nucleotide-binding domain (CNMP-... 55 8e-07 UniRef50_Q695H0 Cluster: CGMP-dependent protein kinase; n=1; Chl... 55 8e-07 UniRef50_UPI0000383B9A Cluster: COG0642: Signal transduction his... 55 1e-06 UniRef50_Q4RR21 Cluster: Chromosome 14 SCAF15003, whole genome s... 55 1e-06 UniRef50_Q2S6T5 Cluster: CAMP-binding protein-catabolite gene ac... 55 1e-06 UniRef50_A0DBC7 Cluster: Chromosome undetermined scaffold_44, wh... 55 1e-06 UniRef50_Q09BB2 Cluster: Cyclic nucleotide-binding:Bacterial reg... 54 1e-06 UniRef50_A0YAY7 Cluster: CAMP-binding protein-catabolite gene ac... 54 1e-06 UniRef50_A0GWU5 Cluster: Stage II sporulation E; n=2; Chloroflex... 54 1e-06 UniRef50_Q3MD80 Cluster: Cyclic nucleotide-binding domain (CNMP-... 54 2e-06 UniRef50_Q5WUW4 Cluster: Putative uncharacterized protein; n=4; ... 54 3e-06 UniRef50_P74736 Cluster: CAMP protein kinase regulatory chain; n... 54 3e-06 UniRef50_A5UY70 Cluster: Cyclic nucleotide-binding protein; n=3;... 54 3e-06 UniRef50_A5PH37 Cluster: AKT2 inward rectifier channel; n=6; Emb... 54 3e-06 UniRef50_O76977 Cluster: Hyperpolarization-activated (Ih) channe... 54 3e-06 UniRef50_A0DKC6 Cluster: Chromosome undetermined scaffold_54, wh... 54 3e-06 UniRef50_A1Z9N7 Cluster: CG8585-PE, isoform E; n=18; Pancrustace... 53 3e-06 UniRef50_UPI000038CAE8 Cluster: COG1252: NADH dehydrogenase, FAD... 53 4e-06 UniRef50_A0DG99 Cluster: Chromosome undetermined scaffold_5, who... 53 4e-06 UniRef50_Q3AAI0 Cluster: CBS/cyclic nucleotide-binding domain pr... 52 6e-06 UniRef50_A7SE96 Cluster: Predicted protein; n=1; Nematostella ve... 52 6e-06 UniRef50_A0DXZ3 Cluster: Chromosome undetermined scaffold_69, wh... 52 6e-06 UniRef50_P74608 Cluster: Slr1575 protein; n=1; Synechocystis sp.... 52 8e-06 UniRef50_Q2ADG0 Cluster: Cyclic nucleotide-binding:Bacterial reg... 52 8e-06 UniRef50_Q7UTR3 Cluster: ATP-binding subunit of ABC transporter;... 52 1e-05 UniRef50_Q46TY3 Cluster: Cyclic nucleotide-binding; n=2; Cupriav... 52 1e-05 UniRef50_Q1D9I5 Cluster: PBS lyase HEAT-like repeat/cyclic nucle... 52 1e-05 UniRef50_Q8ILS1 Cluster: Putative uncharacterized protein; n=1; ... 52 1e-05 UniRef50_Q7RDH4 Cluster: Reticulocyte-binding protein 2 homolog ... 52 1e-05 UniRef50_UPI00006CA698 Cluster: cation channel family protein; n... 51 1e-05 UniRef50_Q09BB3 Cluster: PKA regulatory subunit-like protein; n=... 51 1e-05 UniRef50_A0YLS1 Cluster: Putative uncharacterized protein; n=1; ... 51 1e-05 UniRef50_Q7K3Z6 Cluster: GH01501p; n=4; Diptera|Rep: GH01501p - ... 51 1e-05 UniRef50_Q23EB4 Cluster: ABC transporter family protein; n=3; Te... 51 1e-05 UniRef50_Q4WI41 Cluster: Cyclic nucleotide-binding domain protei... 51 1e-05 UniRef50_A1CZ15 Cluster: Cyclic nucleotide-binding domain protei... 51 1e-05 UniRef50_UPI000038CAE7 Cluster: COG1012: NAD-dependent aldehyde ... 51 2e-05 UniRef50_Q6MJQ6 Cluster: Hyperpolarization-activated, cyclic nuc... 51 2e-05 UniRef50_A3YU63 Cluster: Possible mechanosensitive ion channel; ... 51 2e-05 UniRef50_A3EYY6 Cluster: Tetrameric potassium-selective cyclic n... 51 2e-05 UniRef50_Q10898 Cluster: Uncharacterized protein Rv0104/MT0113; ... 51 2e-05 UniRef50_UPI00006D001F Cluster: cyclic nucleotide-binding domain... 50 2e-05 UniRef50_Q131K0 Cluster: Cyclic nucleotide-binding precursor; n=... 50 2e-05 UniRef50_Q5CD46 Cluster: PKA regulatory subunit homologous prote... 50 2e-05 UniRef50_A6G0I3 Cluster: Putative uncharacterized protein; n=1; ... 50 2e-05 UniRef50_UPI00006CA699 Cluster: cyclic nucleotide-binding domain... 50 3e-05 UniRef50_UPI000065D7C1 Cluster: Homolog of Oncorhynchus mykiss "... 50 3e-05 UniRef50_Q98GM7 Cluster: Mlr3256 protein; n=2; Alphaproteobacter... 50 3e-05 UniRef50_Q2LPZ1 Cluster: Cyclic nucleotide-binding domain protei... 50 3e-05 UniRef50_Q1D5Q4 Cluster: Cyclic nucleotide-binding domain protei... 50 3e-05 UniRef50_Q08NQ8 Cluster: Protein phosphatase 1; n=2; Cystobacter... 50 4e-05 UniRef50_A0YM45 Cluster: Sulfate transporter family protein; n=1... 50 4e-05 UniRef50_Q23WN2 Cluster: Cyclic nucleotide-binding domain contai... 50 4e-05 UniRef50_P63401 Cluster: Uncharacterized ABC transporter ATP-bin... 50 4e-05 UniRef50_UPI00006CC0E9 Cluster: cation channel family protein; n... 49 6e-05 UniRef50_Q2YZI3 Cluster: Putative uncharacterized protein; n=1; ... 49 6e-05 UniRef50_Q1PUQ2 Cluster: Similar to transcriptional regulator of... 49 6e-05 UniRef50_A4M043 Cluster: Transcriptional regulator, Crp/Fnr fami... 49 6e-05 UniRef50_Q4D6P2 Cluster: Regulatory subunit of protein kinase a-... 49 6e-05 UniRef50_Q22R60 Cluster: Cyclic nucleotide-binding domain contai... 49 6e-05 UniRef50_Q8WZA2 Cluster: Rap guanine nucleotide exchange factor ... 49 6e-05 UniRef50_Q9P1Z3 Cluster: Potassium/sodium hyperpolarization-acti... 49 6e-05 UniRef50_Q1GWA6 Cluster: Cyclic nucleotide-binding protein precu... 49 7e-05 UniRef50_Q0VMY3 Cluster: CAMP-dependent protein kinase regulator... 49 7e-05 UniRef50_A0YHV0 Cluster: Putative uncharacterized protein; n=1; ... 49 7e-05 UniRef50_Q00X68 Cluster: Cyclic nucleotide dependent protein kin... 49 7e-05 UniRef50_A4RUE3 Cluster: Predicted protein; n=1; Ostreococcus lu... 49 7e-05 UniRef50_Q23EB1 Cluster: Cation channel family protein; n=2; Tet... 49 7e-05 UniRef50_UPI00006CF9CA Cluster: cation channel family protein; n... 48 1e-04 UniRef50_UPI00006A1C4D Cluster: Uncharacterized protein C20orf15... 48 1e-04 UniRef50_UPI0000EC9E1A Cluster: Rap guanine nucleotide exchange ... 48 1e-04 UniRef50_Q1DAY2 Cluster: Cyclic nucleotide-binding domain protei... 48 1e-04 UniRef50_A6G5Y4 Cluster: Protein phosphatase/cyclic nucleotide-b... 48 1e-04 UniRef50_A0YCM5 Cluster: CAMP-binding protein-catabolite gene ac... 48 1e-04 UniRef50_Q9NQW8 Cluster: Cyclic nucleotide-gated cation channel ... 48 1e-04 UniRef50_Q2SDD5 Cluster: CAMP-binding protein-catabolite gene ac... 48 1e-04 UniRef50_Q08UL3 Cluster: TrkA-N domain family; n=1; Stigmatella ... 48 1e-04 UniRef50_A0LIE9 Cluster: Cyclic nucleotide-binding protein; n=1;... 48 1e-04 UniRef50_Q23EB3 Cluster: Cyclic nucleotide-binding domain contai... 48 1e-04 UniRef50_A7SFW1 Cluster: Predicted protein; n=1; Nematostella ve... 48 1e-04 UniRef50_UPI0000F1F638 Cluster: PREDICTED: similar to putative c... 48 2e-04 UniRef50_UPI00006CFEF7 Cluster: cation channel family protein; n... 48 2e-04 UniRef50_Q5NXU3 Cluster: Catabolite gene activator; n=3; Rhodocy... 48 2e-04 UniRef50_Q2RK98 Cluster: Transcriptional regulator, Crp/Fnr fami... 48 2e-04 UniRef50_Q935V9 Cluster: Transcriptional regulator with cyclic n... 48 2e-04 UniRef50_Q7D4Z5 Cluster: Drug transporter; n=19; Mycobacterium|R... 48 2e-04 UniRef50_Q05VE2 Cluster: Possible mechanosensitive ion channel; ... 48 2e-04 UniRef50_A6GAV1 Cluster: Protein phosphatase/cyclic nucleotide-b... 48 2e-04 UniRef50_A0P0J2 Cluster: Putative catabolite gene activator; n=2... 48 2e-04 UniRef50_Q45ZY2 Cluster: Hyperpolarization-gated and cyclic nucl... 48 2e-04 UniRef50_Q24DS4 Cluster: Cation channel family protein; n=1; Tet... 48 2e-04 UniRef50_Q59V20 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04 UniRef50_Q8XR93 Cluster: Probable transcription regulator protei... 47 2e-04 UniRef50_Q2K3Q8 Cluster: Probable cation transporter protein; n=... 47 2e-04 UniRef50_Q1NMR4 Cluster: Cyclic nucleotide-binding; n=2; delta p... 47 2e-04 UniRef50_Q0LJ13 Cluster: Cyclic nucleotide-binding; n=2; Chlorof... 47 2e-04 UniRef50_A4XWI5 Cluster: Cyclic nucleotide-binding protein; n=2;... 47 2e-04 UniRef50_A1ZHX6 Cluster: Serine/threonine protein kinases; n=1; ... 47 2e-04 UniRef50_A0L6N5 Cluster: Cyclic nucleotide-binding; n=1; Magneto... 47 2e-04 UniRef50_Q554K9 Cluster: CGMP-stimulated cGMP phosphodiesterase;... 47 2e-04 UniRef50_A0CLY8 Cluster: Chromosome undetermined scaffold_21, wh... 47 2e-04 UniRef50_O95398 Cluster: Rap guanine nucleotide exchange factor ... 47 2e-04 UniRef50_Q7V424 Cluster: Possible mechanosensitive ion channel; ... 47 3e-04 UniRef50_Q9X7J4 Cluster: DnrD protein; n=9; Pseudomonas|Rep: Dnr... 47 3e-04 UniRef50_Q1YDI6 Cluster: Possible cAMP-dependent regulatory prot... 47 3e-04 UniRef50_A7SKJ9 Cluster: Predicted protein; n=1; Nematostella ve... 47 3e-04 UniRef50_P34578 Cluster: Uncharacterized protein T20G5.5; n=2; C... 47 3e-04 UniRef50_UPI000065E24B Cluster: Rap guanine nucleotide exchange ... 46 4e-04 UniRef50_Q92SD2 Cluster: PUTATIVE TRANSCRIPTION REGULATOR PROTEI... 46 4e-04 UniRef50_Q30Y06 Cluster: Transcriptional regulator, Crp/Fnr fami... 46 4e-04 UniRef50_Q7CWQ8 Cluster: AGR_C_4670p; n=6; Rhizobiaceae|Rep: AGR... 46 4e-04 UniRef50_Q236Y9 Cluster: Cyclic nucleotide-binding domain contai... 46 4e-04 UniRef50_A0CY63 Cluster: Chromosome undetermined scaffold_301, w... 46 4e-04 UniRef50_P0A642 Cluster: Uncharacterized NTE family protein Rv25... 46 4e-04 UniRef50_UPI00015BC926 Cluster: UPI00015BC926 related cluster; n... 46 5e-04 UniRef50_UPI00006CE543 Cluster: cyclic nucleotide-binding domain... 46 5e-04 UniRef50_UPI00006CB774 Cluster: cyclic nucleotide-binding domain... 46 5e-04 UniRef50_Q2W0I8 Cluster: Kef-type K+ transport systems, predicte... 46 5e-04 UniRef50_Q0VS63 Cluster: Cyclic nucleotide-binding protein; n=1;... 46 5e-04 UniRef50_A0E9X9 Cluster: Chromosome undetermined scaffold_85, wh... 46 5e-04 UniRef50_A0CUC4 Cluster: Chromosome undetermined scaffold_28, wh... 46 5e-04 UniRef50_Q2WA28 Cluster: CheY-like receiver; n=3; Magnetospirill... 46 7e-04 UniRef50_Q2G4A2 Cluster: Cyclic nucleotide-binding domain (CNMP-... 46 7e-04 UniRef50_Q1GTY7 Cluster: Transcriptional regulator, Crp/Fnr fami... 46 7e-04 UniRef50_Q0EYN2 Cluster: Possible mechanosensitive ion channel; ... 46 7e-04 UniRef50_A7BRS9 Cluster: Transcriptional Regulator, Crp/Fnr fami... 46 7e-04 UniRef50_A6G7H5 Cluster: Serine/threonine-protein kinase; n=2; P... 46 7e-04 UniRef50_A5UZM8 Cluster: Cyclic nucleotide-binding protein; n=3;... 46 7e-04 UniRef50_Q23DN4 Cluster: Cyclic nucleotide-binding domain contai... 46 7e-04 UniRef50_A7SKJ5 Cluster: Predicted protein; n=2; Nematostella ve... 46 7e-04 UniRef50_A7RFM7 Cluster: Predicted protein; n=1; Nematostella ve... 46 7e-04 UniRef50_UPI00006D001D Cluster: cation channel family protein; n... 45 9e-04 UniRef50_Q89W82 Cluster: Bll0811 protein; n=3; Bradyrhizobium|Re... 45 9e-04 UniRef50_Q6ANR0 Cluster: Related to nitrogen assimilation regula... 45 9e-04 UniRef50_Q5P0W6 Cluster: Transcriptional regulator, Dnr/Nnr type... 45 9e-04 UniRef50_Q2S8X4 Cluster: CAMP-binding protein-catabolite gene ac... 45 9e-04 UniRef50_Q1YDY1 Cluster: Putative cyclic nucleotide-binding prot... 45 9e-04 UniRef50_Q13J41 Cluster: Transcriptional regulator, Crp/Fnr fami... 45 9e-04 UniRef50_A0XC88 Cluster: Cyclic nucleotide-binding; n=1; Dinoros... 45 9e-04 UniRef50_A7RK87 Cluster: Predicted protein; n=1; Nematostella ve... 45 9e-04 UniRef50_A0E001 Cluster: Chromosome undetermined scaffold_70, wh... 45 9e-04 UniRef50_A0DVS8 Cluster: Chromosome undetermined scaffold_66, wh... 45 9e-04 UniRef50_A0DME6 Cluster: Chromosome undetermined scaffold_56, wh... 45 9e-04 UniRef50_A0DFJ4 Cluster: Chromosome undetermined scaffold_49, wh... 45 9e-04 UniRef50_Q6C384 Cluster: Similar to DEHA0B08261g Debaryomyces ha... 45 9e-04 UniRef50_Q8CXU7 Cluster: CAMP-dependent protein kinase regulator... 45 0.001 UniRef50_Q82V15 Cluster: Cyclic nucleotide-binding domain:cAMP-d... 45 0.001 UniRef50_Q746U7 Cluster: Transcriptional regulator, Crp/Fnr fami... 45 0.001 UniRef50_Q1IHC1 Cluster: Cyclic nucleotide-binding protein; n=1;... 45 0.001 UniRef50_Q0F204 Cluster: Cyclic nucleotide-binding protein; n=1;... 45 0.001 UniRef50_A1ZG79 Cluster: Transporter, small conductance mechanos... 45 0.001 UniRef50_UPI0000D56485 Cluster: PREDICTED: similar to Potassium/... 44 0.002 UniRef50_UPI0000384142 Cluster: COG2199: FOG: GGDEF domain; n=1;... 44 0.002 UniRef50_Q72T22 Cluster: Cyclic nucleotide binding patatin-like ... 44 0.002 UniRef50_Q7D903 Cluster: Cyclic nucleotide-binding protein; n=19... 44 0.002 UniRef50_A7BVI5 Cluster: Reductase; n=1; Beggiatoa sp. PS|Rep: R... 44 0.002 UniRef50_A6G6N1 Cluster: Cyclic nucleotide-binding domain protei... 44 0.002 UniRef50_A1IBE9 Cluster: Putative transcriptional regulator, Crp... 44 0.002 UniRef50_A0NZP6 Cluster: CAAX amino terminal protease family pro... 44 0.002 UniRef50_A0LQJ1 Cluster: Cyclic nucleotide-binding protein; n=1;... 44 0.002 UniRef50_Q23AA7 Cluster: Cation channel family protein; n=1; Tet... 44 0.002 UniRef50_Q23AA4 Cluster: Cation channel family protein; n=1; Tet... 44 0.002 UniRef50_Q22BB2 Cluster: Cyclic nucleotide-binding domain contai... 44 0.002 UniRef50_A5K155 Cluster: Putative uncharacterized protein; n=4; ... 44 0.002 UniRef50_A0BGA2 Cluster: Chromosome undetermined scaffold_105, w... 44 0.002 UniRef50_Q4SKD5 Cluster: Chromosome 13 SCAF14566, whole genome s... 44 0.002 UniRef50_Q89HD2 Cluster: Bll6060 protein; n=3; Bradyrhizobium|Re... 44 0.002 UniRef50_Q7MRZ8 Cluster: DNR; n=1; Wolinella succinogenes|Rep: D... 44 0.002 UniRef50_Q6MLN6 Cluster: Putative uncharacterized protein; n=1; ... 44 0.002 UniRef50_Q47A56 Cluster: Cyclic nucleotide-binding; n=1; Dechlor... 44 0.002 UniRef50_Q3JAP3 Cluster: Cyclic nucleotide-binding protein; n=1;... 44 0.002 UniRef50_Q0LIK4 Cluster: MscS Mechanosensitive ion channel; n=1;... 44 0.002 UniRef50_A4TXU7 Cluster: cAMP-binding protein-catabolite gene ac... 44 0.002 UniRef50_Q237N2 Cluster: Cation channel family protein; n=1; Tet... 44 0.002 UniRef50_A0E296 Cluster: Chromosome undetermined scaffold_74, wh... 44 0.002 UniRef50_Q64359 Cluster: Cyclic nucleotide-gated olfactory chann... 44 0.002 UniRef50_Q1LXY6 Cluster: Novel protein similar to vertebrate cyc... 44 0.003 UniRef50_Q3AF29 Cluster: Transcriptional regulator, Crp/Fnr fami... 44 0.003 UniRef50_Q1N3Q3 Cluster: Putative uncharacterized protein; n=1; ... 44 0.003 UniRef50_Q1D8V4 Cluster: Cyclic nucleotide-binding domain protei... 44 0.003 UniRef50_Q15QG5 Cluster: Transcriptional regulator, Crp/Fnr fami... 44 0.003 UniRef50_A4TW60 Cluster: cAMP-binding protein-catabolite gene ac... 44 0.003 UniRef50_Q22TN5 Cluster: Cation channel family protein; n=2; Tet... 44 0.003 UniRef50_A7SLM9 Cluster: Predicted protein; n=2; Nematostella ve... 44 0.003 UniRef50_A3LZH5 Cluster: Leucine rich repeat protein, contains F... 44 0.003 UniRef50_UPI00006CE52D Cluster: cyclic nucleotide-binding domain... 43 0.004 UniRef50_Q3I0N1 Cluster: Cyclic nucleotide-gated channel beta co... 43 0.004 UniRef50_Q97TL8 Cluster: CRP (Cyclic AMP receptor protein) regul... 43 0.004 UniRef50_Q6N2Q3 Cluster: Probable transcriptional regulator, Crp... 43 0.004 UniRef50_Q31NU6 Cluster: Cyclic nucleotide-binding domain (CNMP-... 43 0.004 UniRef50_A4LZF2 Cluster: Cyclic nucleotide-binding protein; n=2;... 43 0.004 UniRef50_Q23CM4 Cluster: Cyclic nucleotide-binding domain contai... 43 0.004 UniRef50_UPI0001509BB1 Cluster: cyclic nucleotide-binding domain... 43 0.005 UniRef50_Q9CS95 Cluster: 8 days embryo whole body cDNA, RIKEN fu... 43 0.005 UniRef50_Q1EMI3 Cluster: Putative ABC-type transport system, ATP... 43 0.005 UniRef50_Q1D9D3 Cluster: Cyclic nucleotide-binding domain protei... 43 0.005 UniRef50_Q18WV6 Cluster: Transcriptional regulator, Crp/Fnr fami... 43 0.005 UniRef50_A7BRE2 Cluster: Protein kinase, cGMP-dependent, type I;... 43 0.005 UniRef50_A5GPF7 Cluster: Conserved hyppthetical protein; n=1; Sy... 43 0.005 UniRef50_A4U0N5 Cluster: Transcriptional regulator, Crp/Fnr fami... 43 0.005 UniRef50_A2SMH7 Cluster: CAMP-dependent protein kinase-catabolit... 43 0.005 UniRef50_A0NR38 Cluster: Putative Na+/H+ antiporter with cyclic ... 43 0.005 UniRef50_Q23S28 Cluster: Cyclic nucleotide-binding domain contai... 43 0.005 UniRef50_Q03611 Cluster: Cyclic nucleotide-gated cation channel;... 43 0.005 UniRef50_UPI000155D050 Cluster: PREDICTED: similar to Cyclic nuc... 42 0.006 UniRef50_UPI0000F1EF31 Cluster: PREDICTED: similar to cyclic nuc... 42 0.006 UniRef50_UPI00006CFEE1 Cluster: cyclic nucleotide-binding domain... 42 0.006 UniRef50_Q55427 Cluster: Slr0842 protein; n=1; Synechocystis sp.... 42 0.006 UniRef50_P74678 Cluster: DNR protein; n=1; Synechocystis sp. PCC... 42 0.006 UniRef50_A4J9H6 Cluster: Putative transcriptional regulator, Crp... 42 0.006 UniRef50_Q06XL5 Cluster: Inwardly rectifying potassium channel A... 42 0.006 UniRef50_P90975 Cluster: Cyclic nucleotide-gated channel; n=3; C... 42 0.006 UniRef50_A0DV12 Cluster: Chromosome undetermined scaffold_65, wh... 42 0.006 UniRef50_Q4RYB3 Cluster: Chromosome 3 SCAF14978, whole genome sh... 42 0.008 UniRef50_Q8EY25 Cluster: Cyclic nucleotide dependent protein kin... 42 0.008 UniRef50_Q7MBF0 Cluster: Probable transcriptional regulator, Crp... 42 0.008 UniRef50_Q2W4U7 Cluster: CAMP-binding protein-catabolite gene ac... 42 0.008 UniRef50_Q2J6W1 Cluster: Transcriptional regulator, Crp/Fnr fami... 42 0.008 UniRef50_Q1ETT3 Cluster: Cyclic nucleotide-binding:regulatory pr... 42 0.008 UniRef50_Q04S82 Cluster: CAMP-dependent protein kinase; n=4; Lep... 42 0.008 UniRef50_A5U333 Cluster: Crp/Fnr family transcriptional regulato... 42 0.008 UniRef50_A4BIJ9 Cluster: Transcriptional regulator Dnr; n=1; Rei... 42 0.008 UniRef50_A3YVU5 Cluster: Cyclic nucleotide-binding domain (CNMP-... 42 0.008 UniRef50_A1IEY7 Cluster: Putative transcriptional regulator, Crp... 42 0.008 UniRef50_A0NP85 Cluster: Cyclic nucleotide-binding domain (CNMP-... 42 0.008 UniRef50_Q23AA8 Cluster: Cation channel family protein; n=1; Tet... 42 0.008 UniRef50_Q14028 Cluster: Cyclic nucleotide-gated cation channel ... 42 0.008 UniRef50_UPI00006CC101 Cluster: cyclic nucleotide-binding domain... 42 0.011 UniRef50_Q9ER33 Cluster: Cyclic nucleotide-gated channel 2b; n=9... 42 0.011 UniRef50_Q8YY17 Cluster: Transcriptional regulator; n=6; Cyanoba... 42 0.011 UniRef50_Q315Y2 Cluster: Cyclic nucleotide-binding domain (CNMP-... 42 0.011 UniRef50_Q2S0L0 Cluster: Transcription regulator, Crp family, pu... 42 0.011 UniRef50_Q2AEB9 Cluster: Cyclic nucleotide-binding:Bacterial reg... 42 0.011 UniRef50_Q0K1D5 Cluster: Transcriptional regulator CRP family; n... 42 0.011 UniRef50_A5NZN3 Cluster: Cyclic nucleotide-binding protein; n=1;... 42 0.011 UniRef50_Q9LKP2 Cluster: Putative potassium channel protein Kmt1... 42 0.011 UniRef50_Q93486 Cluster: Putative uncharacterized protein cng-1;... 42 0.011 UniRef50_Q16281 Cluster: Cyclic nucleotide-gated cation channel ... 42 0.011 UniRef50_UPI00005890C6 Cluster: PREDICTED: similar to 240K prote... 41 0.015 UniRef50_Q3M891 Cluster: Transcriptional Regulator, Crp/Fnr fami... 41 0.015 UniRef50_Q2JXE2 Cluster: Cyclic nucleotide-binding protein, trun... 41 0.015 UniRef50_Q0EX27 Cluster: Cyclic nucleotide-binding:Bacterial reg... 41 0.015 UniRef50_Q01YJ3 Cluster: Cyclic nucleotide-binding protein precu... 41 0.015 UniRef50_A7HSM8 Cluster: Cyclic nucleotide-binding protein; n=1;... 41 0.015 UniRef50_A5UY24 Cluster: Cyclic nucleotide-binding protein; n=2;... 41 0.015 UniRef50_A1B7P5 Cluster: Putative transcriptional regulator, Crp... 41 0.015 UniRef50_A4S699 Cluster: Predicted protein; n=2; Ostreococcus|Re... 41 0.015 UniRef50_Q23YQ2 Cluster: Cyclic nucleotide-binding domain contai... 41 0.015 UniRef50_Q23R10 Cluster: Cation channel family protein; n=1; Tet... 41 0.015 UniRef50_Q236Y8 Cluster: Cyclic nucleotide-binding domain contai... 41 0.015 UniRef50_A0CUS7 Cluster: Chromosome undetermined scaffold_28, wh... 41 0.015 UniRef50_A0CB28 Cluster: Chromosome undetermined scaffold_163, w... 41 0.015 UniRef50_UPI00006CC00D Cluster: hypothetical protein TTHERM_0041... 41 0.019 UniRef50_UPI00006CA695 Cluster: cyclic nucleotide-binding domain... 41 0.019 UniRef50_Q1EWQ8 Cluster: Cyclic nucleotide-binding:regulatory pr... 41 0.019 UniRef50_A5PA10 Cluster: Cyclic nucleotide-binding protein; n=1;... 41 0.019 UniRef50_UPI0000D56B62 Cluster: PREDICTED: similar to Potassium/... 40 0.025 UniRef50_Q72VQ9 Cluster: Cyclic nucleotide binding protein; n=4;... 40 0.025 UniRef50_Q0LK35 Cluster: Cyclic nucleotide-binding; n=1; Herpeto... 40 0.025 UniRef50_Q0FXM0 Cluster: Putative catabolite gene activator; n=1... 40 0.025 UniRef50_A7IGJ4 Cluster: Cyclic nucleotide-binding protein; n=1;... 40 0.025 UniRef50_A7HF79 Cluster: Cyclic nucleotide-binding protein; n=1;... 40 0.025 UniRef50_A0LNW4 Cluster: Transcriptional regulator, Crp/Fnr fami... 40 0.025 UniRef50_Q22YR2 Cluster: Cyclic nucleotide-binding domain contai... 40 0.025 UniRef50_A7STN1 Cluster: Predicted protein; n=2; Nematostella ve... 40 0.025 UniRef50_A7RGK0 Cluster: Predicted protein; n=1; Nematostella ve... 40 0.025 UniRef50_A0BIM1 Cluster: Chromosome undetermined scaffold_11, wh... 40 0.025 UniRef50_Q6BWV4 Cluster: Debaryomyces hansenii chromosome B of s... 40 0.025 UniRef50_UPI0000D556B8 Cluster: PREDICTED: similar to cyclic nuc... 40 0.034 UniRef50_UPI00006CFB0C Cluster: cyclic nucleotide-binding domain... 40 0.034 UniRef50_UPI00006CE534 Cluster: cyclic nucleotide-binding domain... 40 0.034 UniRef50_UPI00006CCBC9 Cluster: cyclic nucleotide-binding domain... 40 0.034 UniRef50_UPI000065F344 Cluster: Cyclic nucleotide-gated olfactor... 40 0.034 UniRef50_Q4T9V2 Cluster: Chromosome undetermined SCAF7488, whole... 40 0.034 UniRef50_Q4SKL1 Cluster: Chromosome undetermined SCAF14565, whol... 40 0.034 UniRef50_Q98GN8 Cluster: Mll3241 protein; n=2; Rhizobiales|Rep: ... 40 0.034 UniRef50_O83286 Cluster: Catabolite gene activator; n=2; Trepone... 40 0.034 UniRef50_Q2N5Y8 Cluster: Cyclic nucleotide-binding; n=1; Erythro... 40 0.034 UniRef50_Q12IK7 Cluster: Cyclic nucleotide-binding; n=1; Shewane... 40 0.034 UniRef50_A6G6X5 Cluster: Predicted signal transduction protein c... 40 0.034 UniRef50_A0L8L8 Cluster: Cyclic nucleotide-binding protein; n=1;... 40 0.034 UniRef50_Q89CE1 Cluster: Blr7856 protein; n=2; Bradyrhizobium|Re... 40 0.045 UniRef50_Q74BP9 Cluster: Transcriptional regulator, Crp/Fnr fami... 40 0.045 UniRef50_Q21JY8 Cluster: Cyclic nucleotide-binding; n=1; Sacchar... 40 0.045 UniRef50_Q12FL8 Cluster: Cyclic nucleotide-binding; n=1; Polarom... 40 0.045 UniRef50_A4BEG8 Cluster: Putative uncharacterized protein; n=1; ... 40 0.045 UniRef50_A4B0Y5 Cluster: Cyclic nucleotide-binding protein; n=1;... 40 0.045 UniRef50_A3VL67 Cluster: Putative uncharacterized protein; n=1; ... 40 0.045 UniRef50_Q23K39 Cluster: Cation channel family protein; n=1; Tet... 40 0.045 UniRef50_Q23AA5 Cluster: Cyclic nucleotide-binding domain contai... 40 0.045 UniRef50_A4VDK5 Cluster: Voltage and ligand gated potassium chan... 40 0.045 UniRef50_Q24278 Cluster: Cyclic nucleotide-gated cation channel;... 40 0.045 UniRef50_Q82GX1 Cluster: Putative transcriptional regulator with... 39 0.059 UniRef50_Q7NK18 Cluster: Gll1662 protein; n=1; Gloeobacter viola... 39 0.059 UniRef50_Q0ANV8 Cluster: Cyclic nucleotide-binding protein; n=2;... 39 0.059 UniRef50_Q076H6 Cluster: N-acyl phenylalanine synthase; n=1; unc... 39 0.059 UniRef50_A5CYD6 Cluster: Hypothetical transcriptional regulator;... 39 0.059 UniRef50_A1ZRY9 Cluster: Transporter, small conductance mechanos... 39 0.059 UniRef50_Q01CK0 Cluster: Predicted esterase of the alpha-beta hy... 39 0.059 UniRef50_Q23K40 Cluster: Cyclic nucleotide-binding domain contai... 39 0.059 UniRef50_Q23EB8 Cluster: Cyclic nucleotide-binding domain contai... 39 0.059 UniRef50_Q22AP6 Cluster: Cation channel family protein; n=1; Tet... 39 0.059 UniRef50_O97119 Cluster: Cyclic nucleotide-gated ion channel LCN... 39 0.059 UniRef50_A2DY06 Cluster: Cyclic nucleotide-binding domain contai... 39 0.059 UniRef50_Q5KQ28 Cluster: Vacuole protein, putative; n=1; Filobas... 39 0.059 UniRef50_UPI0000384141 Cluster: COG0664: cAMP-binding proteins -... 39 0.078 UniRef50_Q6MLB6 Cluster: Putative uncharacterized protein; n=1; ... 39 0.078 UniRef50_Q6MIF1 Cluster: Probable cyclic nucleotide binding prot... 39 0.078 UniRef50_Q30QZ1 Cluster: Putative transcriptional regulator, Crp... 39 0.078 UniRef50_Q0AWK5 Cluster: Putative uncharacterized protein; n=1; ... 39 0.078 UniRef50_Q03UH4 Cluster: Crp-like transcriptional regulator; n=2... 39 0.078 UniRef50_A7C611 Cluster: Cyclic nucleotide-binding; n=1; Beggiat... 39 0.078 UniRef50_A0UXQ0 Cluster: Transcriptional regulator, Crp/Fnr fami... 39 0.078 UniRef50_Q23CM8 Cluster: Cyclic nucleotide-binding domain contai... 39 0.078 UniRef50_A0DV88 Cluster: Chromosome undetermined scaffold_65, wh... 39 0.078 UniRef50_Q2HCN1 Cluster: Putative uncharacterized protein; n=1; ... 39 0.078 UniRef50_Q0TZR7 Cluster: Putative uncharacterized protein; n=1; ... 39 0.078 UniRef50_A5DFW8 Cluster: Putative uncharacterized protein; n=1; ... 39 0.078 UniRef50_P92960 Cluster: Potassium channel KAT3; n=7; core eudic... 39 0.078 UniRef50_UPI0000D568C5 Cluster: PREDICTED: similar to sperm-spec... 38 0.10 UniRef50_Q7NIH1 Cluster: Glr2212 protein; n=2; Cyanobacteria|Rep... 38 0.10 UniRef50_Q7M956 Cluster: PUTATIVE TRANSCRIPTIONAL REGULATOR; n=1... 38 0.10 UniRef50_Q44026 Cluster: Orf2 protein; n=3; Cupriavidus|Rep: Orf... 38 0.10 UniRef50_Q04QT5 Cluster: CAMP-binding protein; n=4; Leptospira|R... 38 0.10 UniRef50_A5NX32 Cluster: Cyclic nucleotide-binding protein; n=1;... 38 0.10 UniRef50_A4TW57 Cluster: cAMP-binding proteins-catabolite gene a... 38 0.10 UniRef50_A1IDX0 Cluster: Putative transcriptional regulator, Crp... 38 0.10 UniRef50_A1EWE7 Cluster: Conserved domain protein; n=5; Coxiella... 38 0.10 UniRef50_A0DKI0 Cluster: Chromosome undetermined scaffold_54, wh... 38 0.10 UniRef50_A7EKJ1 Cluster: Putative uncharacterized protein; n=1; ... 38 0.10 UniRef50_Q5ZVB5 Cluster: CAAX amino terminal protease family pro... 38 0.14 UniRef50_Q2W0D8 Cluster: CAMP-binding protein-catabolite gene ac... 38 0.14 UniRef50_Q51661 Cluster: Fnr-like transcriptional activator; n=2... 38 0.14 UniRef50_Q0PQI4 Cluster: Transcriptional regulator Crp/Fnr; n=1;... 38 0.14 UniRef50_A6NUW6 Cluster: Putative uncharacterized protein; n=1; ... 38 0.14 UniRef50_Q22YR4 Cluster: Cyclic nucleotide-binding domain contai... 38 0.14 UniRef50_Q22U43 Cluster: Cyclic nucleotide-binding domain contai... 38 0.14 UniRef50_A0E0P5 Cluster: Chromosome undetermined scaffold_72, wh... 38 0.14 UniRef50_Q6CWE3 Cluster: Similarities with ca|CA0961|IPF18822 Ca... 38 0.14 UniRef50_UPI0000F1EB53 Cluster: PREDICTED: hypothetical protein,... 38 0.18 UniRef50_UPI0000DB7A09 Cluster: PREDICTED: similar to CG8958-PA;... 38 0.18 UniRef50_UPI00006CB9F6 Cluster: cation channel family protein; n... 38 0.18 UniRef50_UPI00006CB8EE Cluster: cyclic nucleotide-binding domain... 38 0.18 UniRef50_Q21HQ8 Cluster: Cyclic nucleotide-binding; n=1; Sacchar... 38 0.18 UniRef50_Q1K454 Cluster: Cyclic nucleotide-binding protein; n=1;... 38 0.18 UniRef50_A7HRV0 Cluster: Putative transcriptional regulator, Crp... 38 0.18 UniRef50_A0NZG3 Cluster: CAMP-binding protein-catabolite gene ac... 38 0.18 UniRef50_A0LQJ4 Cluster: Cyclic nucleotide-binding protein; n=1;... 38 0.18 UniRef50_Q9W201 Cluster: CG3536-PA; n=3; Sophophora|Rep: CG3536-... 38 0.18 UniRef50_Q23AA6 Cluster: Cation channel family protein; n=1; Tet... 38 0.18 UniRef50_Q22U44 Cluster: Cyclic nucleotide-binding domain contai... 38 0.18 UniRef50_A0D169 Cluster: Chromosome undetermined scaffold_34, wh... 38 0.18 UniRef50_UPI0000F21589 Cluster: PREDICTED: similar to 240K prote... 37 0.24 UniRef50_UPI00006CAF68 Cluster: cyclic nucleotide-binding domain... 37 0.24 UniRef50_UPI0000383B0E Cluster: COG0664: cAMP-binding proteins -... 37 0.24 UniRef50_Q8G502 Cluster: Probable transcriptional regulator with... 37 0.24 UniRef50_Q7WBP4 Cluster: Probable regulator; n=2; Bordetella|Rep... 37 0.24 UniRef50_Q6MNF7 Cluster: Putative uncharacterized protein; n=1; ... 37 0.24 UniRef50_Q6AL49 Cluster: Probable transcription regulator; n=1; ... 37 0.24 UniRef50_Q5L1Y8 Cluster: Transcriptional regulator; n=3; Bacilla... 37 0.24 UniRef50_Q2SHS2 Cluster: CAMP-binding protein-catabolite gene ac... 37 0.24 UniRef50_Q21SN7 Cluster: Transcriptional regulator, Crp/Fnr fami... 37 0.24 UniRef50_Q1K2E6 Cluster: Cyclic nucleotide-binding protein; n=1;... 37 0.24 UniRef50_Q0S8M5 Cluster: Transcriptional regulator; n=50; Actino... 37 0.24 UniRef50_Q07HN5 Cluster: Transcriptional regulator, Crp/Fnr fami... 37 0.24 UniRef50_A7DIK0 Cluster: Cyclic nucleotide-binding protein; n=2;... 37 0.24 UniRef50_A7C5Z1 Cluster: Putative uncharacterized protein; n=1; ... 37 0.24 UniRef50_A6UE01 Cluster: Cyclic nucleotide-binding protein; n=5;... 37 0.24 UniRef50_A5NVT2 Cluster: Cyclic nucleotide-binding protein; n=1;... 37 0.24 UniRef50_A1ARS9 Cluster: Transcriptional regulator, Crp/Fnr fami... 37 0.24 UniRef50_Q22TM9 Cluster: Cyclic nucleotide-binding domain contai... 37 0.24 UniRef50_P0ACK1 Cluster: Catabolite gene activator; n=101; Gamma... 37 0.24 UniRef50_Q9SJA4 Cluster: Probable cyclic nucleotide-gated ion ch... 37 0.24 UniRef50_UPI00006CC92E Cluster: cyclic nucleotide-binding domain... 37 0.31 UniRef50_Q5LKQ8 Cluster: Cyclic nucleotide-binding protein; n=3;... 37 0.31 UniRef50_Q4ZZV6 Cluster: Cyclic nucleotide-binding; n=3; Pseudom... 37 0.31 UniRef50_Q8VQZ4 Cluster: Histidine kinase-like protein; n=2; Myx... 37 0.31 UniRef50_Q4C464 Cluster: Cyclic nucleotide-binding:Sulfate trans... 37 0.31 UniRef50_A0NV10 Cluster: Cyclic nucleotide-binding:Bacterial reg... 37 0.31 UniRef50_Q248A3 Cluster: Cyclic nucleotide-binding domain contai... 37 0.31 UniRef50_Q22C85 Cluster: Cation channel family protein; n=1; Tet... 37 0.31 UniRef50_A0DK81 Cluster: Chromosome undetermined scaffold_54, wh... 37 0.31 UniRef50_A7TIE8 Cluster: Putative uncharacterized protein; n=1; ... 37 0.31 UniRef50_UPI00006CF2CA Cluster: cyclic nucleotide-binding domain... 36 0.41 UniRef50_Q4SDJ0 Cluster: Chromosome 18 SCAF14637, whole genome s... 36 0.41 UniRef50_Q5ZY24 Cluster: Putative uncharacterized protein; n=4; ... 36 0.41 UniRef50_Q31RQ1 Cluster: Cyclic nucleotide-binding domain (CNMP-... 36 0.41 UniRef50_Q31M75 Cluster: Cyclic nucleotide-binding domain (CNMP-... 36 0.41 UniRef50_Q2AH01 Cluster: Cyclic nucleotide-binding:Bacterial reg... 36 0.41 UniRef50_Q121L3 Cluster: Cyclic nucleotide-binding domain (CNMP-... 36 0.41 UniRef50_A7HBD8 Cluster: Putative uncharacterized protein; n=1; ... 36 0.41 UniRef50_A6G9I3 Cluster: Cyclic nucleotide-binding domain (CNMP-... 36 0.41 >UniRef50_Q7PPI8 Cluster: ENSANGP00000022232; n=3; Endopterygota|Rep: ENSANGP00000022232 - Anopheles gambiae str. PEST Length = 381 Score = 239 bits (585), Expect = 3e-62 Identities = 112/165 (67%), Positives = 139/165 (84%) Frame = +2 Query: 20 KPPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQ 199 KP V R+ +RRKSVFAETYDPE DD DEGA A+FPK+D QRARL ++V+ ILLFRSLD + Sbjct: 75 KPLVNRYASRRKSVFAETYDPENDDEDEGARAIFPKTDEQRARLCDSVKNILLFRSLDKE 134 Query: 200 QMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS 379 QM +VLDAMFEK + +Y+I+QGDDGDNFYVIE+G+++ V G+D +K +HTY+ GS Sbjct: 135 QMNEVLDAMFEKIVQAKDYIIKQGDDGDNFYVIESGIYNAYV-GED--QKHIHTYDNRGS 191 Query: 380 FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 FGELAL+YNMPRAA+++A+T G LWAMDR TFRRILLKSAF+KRK Sbjct: 192 FGELALLYNMPRAATIQAETDGKLWAMDRQTFRRILLKSAFRKRK 236 Score = 60.5 bits (140), Expect = 2e-08 Identities = 37/122 (30%), Positives = 62/122 (50%), Gaps = 1/122 (0%) Frame = +2 Query: 125 KSDAQRARLAEAVR-GILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIE 301 KS ++ ++ EA+ + + ++L + + DA+ + G+ +I+QGD D Y IE Sbjct: 229 KSAFRKRKMYEALLDAVPMLKTLQNYERMNLADALIPQTYAKGDRIIKQGDAADGMYFIE 288 Query: 302 NGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481 +G + + D E + E G FGELAL+ + PRAAS A + +D F R Sbjct: 289 DGKVSIRIQ-QDAGEVEISNLEKGGYFGELALVTHRPRAASAYAVDNVKVAFLDVDAFER 347 Query: 482 IL 487 +L Sbjct: 348 LL 349 >UniRef50_P81900 Cluster: cAMP-dependent protein kinase type II regulatory subunit; n=17; Eumetazoa|Rep: cAMP-dependent protein kinase type II regulatory subunit - Drosophila melanogaster (Fruit fly) Length = 377 Score = 232 bits (568), Expect = 3e-60 Identities = 109/165 (66%), Positives = 138/165 (83%) Frame = +2 Query: 20 KPPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQ 199 +PPV ++RRKSVFAE YDPE DD D+GA AVFPK+D QRARL E+V+ +LLFRSL+ + Sbjct: 73 EPPVMA-SSRRKSVFAEAYDPEADDDDDGATAVFPKTDEQRARLVESVKNVLLFRSLEKE 131 Query: 200 QMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS 379 QM QVLDAMFE++ +PG+++IRQGDDGDNFYVIE+GV+ V + +K ++TY +G Sbjct: 132 QMNQVLDAMFERKVQPGDFIIRQGDDGDNFYVIESGVYKVYIN-----DKHINTYNHTGL 186 Query: 380 FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 FGELAL+YNMPRAA+V+A+T+G LWAMDR TFRRILLKSAF+KRK Sbjct: 187 FGELALLYNMPRAATVQAETSGLLWAMDRQTFRRILLKSAFRKRK 231 Score = 64.5 bits (150), Expect = 1e-09 Identities = 41/119 (34%), Positives = 61/119 (51%), Gaps = 2/119 (1%) Frame = +2 Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316 +R E + + + ++L + + DA+ K + GE +I+QGD D Y IE G Sbjct: 229 KRKMYEELLNSVPMLKALQNYERMNLADALVSKSYDNGERIIKQGDAADGMYFIEEGTVS 288 Query: 317 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGA--LWAMDRHTFRRIL 487 V + DD ++ +G FGELAL+ + PRAASV A T G L +D F R+L Sbjct: 289 VRMDQDDAEVEISQLGKGQ-YFGELALVTHRPRAASVYA-TGGVVKLAFLDVKAFERLL 345 >UniRef50_Q5DI18 Cluster: SJCHGC02266 protein; n=1; Schistosoma japonicum|Rep: SJCHGC02266 protein - Schistosoma japonicum (Blood fluke) Length = 377 Score = 192 bits (467), Expect = 5e-48 Identities = 93/158 (58%), Positives = 115/158 (72%), Gaps = 1/158 (0%) Frame = +2 Query: 44 NRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDA 223 +RR V AE+YDPE+DDS V PK++ QR RL +A + ILLFR LD QM+ V+DA Sbjct: 74 SRRAGVAAESYDPEKDDSSSAVKVVHPKTEEQRQRLTQATKDILLFRCLDDDQMKDVIDA 133 Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV-TGDDRVEKVVHTYEGSGSFGELALM 400 MFE+ PGE VI G+DGDNFYVIE GV+D++V GD+ EKVV Y+ GSFGELALM Sbjct: 134 MFERHVSPGEKVITLGEDGDNFYVIEKGVYDIIVKVGDE--EKVVGKYDNKGSFGELALM 191 Query: 401 YNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 YN PRAA++ A+T G LWAM R FR I+LK AF+KR+ Sbjct: 192 YNTPRAATILAKTEGVLWAMTREVFRSIVLKKAFEKRR 229 Score = 71.3 bits (167), Expect = 1e-11 Identities = 42/125 (33%), Positives = 62/125 (49%), Gaps = 1/125 (0%) Frame = +2 Query: 116 VFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYV 295 V K+ +R E + + + SL A + + DA+ K E E +I+QGD GD + Sbjct: 220 VLKKAFEKRRLYEELLNQVPILESLSAYERMSIADALRTKIFEANEQIIKQGDPGDEMFF 279 Query: 296 IENGVFDV-LVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHT 472 +E G + + + EK V E G FGELAL+ + PRAAS A L +D + Sbjct: 280 VEEGKVSIKMKRSGETEEKEVAVIEKGGYFGELALLTSHPRAASAYADCRTKLAVLDVGS 339 Query: 473 FRRIL 487 F R+L Sbjct: 340 FERLL 344 >UniRef50_P31323 Cluster: cAMP-dependent protein kinase type II-beta regulatory subunit; n=56; Deuterostomia|Rep: cAMP-dependent protein kinase type II-beta regulatory subunit - Homo sapiens (Human) Length = 418 Score = 189 bits (460), Expect = 4e-47 Identities = 94/164 (57%), Positives = 119/164 (72%) Frame = +2 Query: 23 PPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQ 202 P + RF RR SV AE Y+P+E++ D + + PK+D QR RL EA + ILLF++LD +Q Sbjct: 104 PVINRFT-RRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQ 162 Query: 203 MQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF 382 M QVLDAMFEK + GE+VI QGDDGDNFYVI+ G FD+ V D V + V Y+ GSF Sbjct: 163 MSQVLDAMFEKLVKDGEHVIDQGDDGDNFYVIDRGTFDIYVKCDG-VGRCVGNYDNRGSF 221 Query: 383 GELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 GELALMYN PRAA++ A + GALW +DR TFRRI++K+ KKRK Sbjct: 222 GELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRK 265 Score = 63.7 bits (148), Expect = 2e-09 Identities = 42/131 (32%), Positives = 69/131 (52%), Gaps = 7/131 (5%) Frame = +2 Query: 116 VFPKSDAQRARLAEA-VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFY 292 + K++A++ ++ E+ + + +SL+ + +V+D + K GE +I QGD D+F+ Sbjct: 255 IIVKNNAKKRKMYESFIESLPFLKSLEFSERLKVVDVIGTKVYNDGEQIIAQGDSADSFF 314 Query: 293 VIENGVFDVLV--TGDDRVEK--VVHTYEGSGS--FGELALMYNMPRAASVRAQTAGALW 454 ++E+G + + G VE+ V S FGELAL+ N PRAAS A Sbjct: 315 IVESGEVKITMKRKGKSEVEENGAVEMPRCSRGQYFGELALVTNKPRAASAHAIGTVKCL 374 Query: 455 AMDRHTFRRIL 487 AMD F R+L Sbjct: 375 AMDVQAFERLL 385 >UniRef50_Q4RSC3 Cluster: Chromosome 13 SCAF15000, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 13 SCAF15000, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 422 Score = 173 bits (422), Expect = 2e-42 Identities = 92/175 (52%), Positives = 118/175 (67%), Gaps = 11/175 (6%) Frame = +2 Query: 23 PPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQ 202 P + RF+ RR SV AE ++P+ED+ ++ PK+D QR RL EA R ILLF++LD ++ Sbjct: 127 PVINRFS-RRASVCAEAFNPDEDEEEKEPLVTHPKTDEQRQRLQEACRDILLFKNLDPEE 185 Query: 203 MQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF 382 M QVLDAMFEK GE++I Q DDGDNFYVIE+G F + V D EK+V Y+ GSF Sbjct: 186 MSQVLDAMFEKFCTEGEHIIDQDDDGDNFYVIESGTFSIFVK-TDSTEKLVGCYDNRGSF 244 Query: 383 GELALMYNMPRAASVRAQTAGALWAM-----------DRHTFRRILLKSAFKKRK 514 GELALMYN PRAA++ A + GALW + DR TFRRI++K+ KKRK Sbjct: 245 GELALMYNTPRAATIIATSTGALWCLAIKATQQEKQQDRLTFRRIIVKNNAKKRK 299 Score = 33.9 bits (74), Expect = 2.2 Identities = 22/53 (41%), Positives = 27/53 (50%), Gaps = 1/53 (1%) Frame = +2 Query: 332 DDRVEKV-VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 D E+V + T FGELAL+ N PRAAS A + MD F R+L Sbjct: 344 DPEEEEVDIATLSRGQYFGELALVTNKPRAASAYAVGSVKCLVMDVKAFERLL 396 >UniRef50_P31320 Cluster: cAMP-dependent protein kinase regulatory subunit; n=1; Blastocladiella emersonii|Rep: cAMP-dependent protein kinase regulatory subunit - Blastocladiella emersonii (Aquatic fungus) Length = 403 Score = 148 bits (359), Expect = 6e-35 Identities = 81/164 (49%), Positives = 97/164 (59%) Frame = +2 Query: 23 PPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQ 202 PPV RR SV AE+ P D D V PKSD QRAR+ ++ LFR+LD Q Sbjct: 107 PPVVN-RGRRTSVSAESMAPTAHDVD-AVKTVIPKSDEQRARIQASIGNNFLFRNLDEDQ 164 Query: 203 MQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF 382 V++AM EK+ GE VIRQG GD FYV+E G DV V + + V Y GSF Sbjct: 165 YTDVVNAMAEKKVAAGEVVIRQGGVGDYFYVVETGALDVFVNRNGNGDVKVTDYSAGGSF 224 Query: 383 GELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 GELALMYN PRAA+V A LWA+DR TFRRIL+ +KR+ Sbjct: 225 GELALMYNAPRAATVVATAESVLWALDRVTFRRILMDHTSRKRR 268 Score = 66.5 bits (155), Expect = 3e-10 Identities = 38/119 (31%), Positives = 64/119 (53%), Gaps = 1/119 (0%) Frame = +2 Query: 134 AQRARLAEA-VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGV 310 +++ R+ EA + + L SL+ + ++ DA+ G+ VIRQGD G+NFY+IE G Sbjct: 264 SRKRRMYEAFLEEVPLLSSLEPYERHKIADALESVAYADGDVVIRQGDVGENFYIIEAGD 323 Query: 311 FDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 +V+ ++ E FGELAL+ + PR A++RA+ + + F R+L Sbjct: 324 AEVIKIDENGEEHHFRPLHKGNYFGELALLSDKPRVATIRAKGKLKCAKLGKKAFTRLL 382 >UniRef50_A7RGJ3 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 390 Score = 139 bits (336), Expect = 4e-32 Identities = 71/156 (45%), Positives = 98/156 (62%) Frame = +2 Query: 47 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226 RR SV E Y+P + A +PKS+ R RL + I +F+S Q+ +LDAM Sbjct: 88 RRDSVAGEVYEPVNSNC-VSAQRFYPKSEDARKRLENVIGNIFIFKSCGKDQINMMLDAM 146 Query: 227 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYN 406 +E+ E +IRQGD GDNFY+I+ G F+VL + EK + +G GSFGELALMYN Sbjct: 147 YERVVYQEETIIRQGDAGDNFYIIDEGEFEVLFETNGAQEK-LGRLKGPGSFGELALMYN 205 Query: 407 MPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 PR+A++RA T G LW +DR +FRRIL+ + +KR+ Sbjct: 206 CPRSATIRACTPGVLWVLDRKSFRRILVDTTERKRR 241 Score = 49.2 bits (112), Expect = 6e-05 Identities = 36/123 (29%), Positives = 58/123 (47%), Gaps = 3/123 (2%) Frame = +2 Query: 128 SDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG 307 ++ +R + I + L A + + DA+ E +IRQ D D Y IE+G Sbjct: 236 TERKRRHYETLLERIPVLSQLTAYERTSLADALTTSVYRDEECIIRQDDPADCLYFIESG 295 Query: 308 VFDVLV-TGDDRVE-KVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWA-MDRHTFR 478 + ++ + DR + KV+ T FGELAL+ R ASV A+ A ++ + F Sbjct: 296 IVEISIRDSKDRSKVKVISTAGPGEYFGELALVNKTKRGASVHAKGGQVTCAVLEVNAFE 355 Query: 479 RIL 487 R+L Sbjct: 356 RLL 358 >UniRef50_A7S513 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 373 Score = 132 bits (319), Expect = 5e-30 Identities = 67/164 (40%), Positives = 103/164 (62%), Gaps = 1/164 (0%) Frame = +2 Query: 26 PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQM 205 P+ + +RR +V AE Y+P E+ +D A PKS+ QR L + + + LF + + Sbjct: 75 PIIKGRSRRAAVSAEPYNPNEN-ADFKAK-FHPKSEEQRNHLKKKLLELWLFEKFHREDL 132 Query: 206 QQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKV-VHTYEGSGSF 382 +LD+MFEK+ P E +I+ GD+GDNFYVI G +DV + + VHT+ G+G F Sbjct: 133 DVILDSMFEKKVSPEEIIIKVGDEGDNFYVINTGEYDVFALDTNTGASIKVHTFNGTGMF 192 Query: 383 GELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 GELALM+N R A++ A+T G LWA+DR TF ++++ A ++R+ Sbjct: 193 GELALMHNSLRNATIVAKTEGTLWALDRSTFVQVVVGGAQRRRE 236 Score = 62.5 bits (145), Expect = 6e-09 Identities = 40/118 (33%), Positives = 62/118 (52%), Gaps = 1/118 (0%) Frame = +2 Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDN-FYVIENGVF 313 +R R E ++ + + + L ++ +V DA++ K + GE VIR+G++ Y IE G Sbjct: 234 RRERNIELLKSVSILKELKPDELDKVSDALYPKEFKDGEAVIREGNESAYCMYFIEKGKV 293 Query: 314 DVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 V V D VEK V FGELAL+ N PR+ASV A ++ + F R++ Sbjct: 294 RVTVK-DGEVEKTVEF--DKNYFGELALVMNQPRSASVYAVGECKFASLKKDDFERLM 348 >UniRef50_A6SCU8 Cluster: Putative uncharacterized protein; n=2; Sclerotiniaceae|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 468 Score = 132 bits (318), Expect = 6e-30 Identities = 79/165 (47%), Positives = 99/165 (60%), Gaps = 9/165 (5%) Frame = +2 Query: 47 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226 RR SV AE+ +P +D +P K+ Q ARL +++ G LF LD +Q QVL A+ Sbjct: 169 RRTSVSAESLNPTASSNDNWSPPFHQKTQDQVARLKKSISGNFLFSHLDDEQSAQVLGAL 228 Query: 227 FEKR-SEPGEYVIRQGDDGDNFYVIENGVFDV-------LVTGDDRVEKVVHTYEGSGSF 382 EK G VI QGD GD FYV+E G FDV L G D + V T E GSF Sbjct: 229 VEKPIPAVGIKVISQGDQGDFFYVVEKGSFDVHVNSTGSLQPGPDGLGTKVATIEPGGSF 288 Query: 383 GELALMYNMPRAASV-RAQTAGALWAMDRHTFRRILLKSAFKKRK 514 GELALMYN PRAA+V A+ + LWA+DR TFRRIL+ S F++R+ Sbjct: 289 GELALMYNAPRAATVISAEASCTLWALDRITFRRILMDSTFQRRR 333 Score = 67.7 bits (158), Expect = 1e-10 Identities = 40/121 (33%), Positives = 68/121 (56%), Gaps = 1/121 (0%) Frame = +2 Query: 128 SDAQRARLAEA-VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 304 S QR RL E+ + + L +L + ++ DA+ ++ PG +I +GD G+ FY++E+ Sbjct: 327 STFQRRRLYESFLEEVPLLSTLTRYERSKIADALETQKYPPGTAIINEGDAGEAFYLLES 386 Query: 305 GVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484 G + G V+ V Y FGELAL+ + PRAASV ++T + + ++ F+R+ Sbjct: 387 GEAEAYKRG---VDNPVKLYHKGDYFGELALLNDAPRAASVVSKTEVKVATLGKNGFQRL 443 Query: 485 L 487 L Sbjct: 444 L 444 >UniRef50_Q5H7P2 Cluster: CAMP-dependent protein kinase regulatory subunit; n=1; Aspergillus oryzae|Rep: CAMP-dependent protein kinase regulatory subunit - Aspergillus oryzae Length = 416 Score = 131 bits (317), Expect = 8e-30 Identities = 77/165 (46%), Positives = 98/165 (59%), Gaps = 9/165 (5%) Frame = +2 Query: 47 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226 RR SV AE+ +P SD P PK++ Q +RL AV G LF LD Q + V+DA+ Sbjct: 119 RRTSVSAESLNPTSAGSDSWVPPHHPKTEEQVSRLKTAVSGNFLFSHLDDDQFKTVVDAL 178 Query: 227 FEKR-SEPGEYVIRQGDDGDNFYVIENGVFDVLV-------TGDDRVEKVVHTYEGSGSF 382 EK G VI QGD GD FY++E+G FDV + +G D + T GSF Sbjct: 179 VEKPIPAKGIKVISQGDAGDYFYIVEDGHFDVYIHPSGSVQSGSDGMGSKAGTIGPGGSF 238 Query: 383 GELALMYNMPRAAS-VRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 GELALMYN PRAA+ V + LWA+DR TFRRIL+ SAF++R+ Sbjct: 239 GELALMYNAPRAATIVSTDSKSTLWALDRITFRRILMDSAFQRRR 283 Score = 70.9 bits (166), Expect = 2e-11 Identities = 42/118 (35%), Positives = 67/118 (56%), Gaps = 1/118 (0%) Frame = +2 Query: 137 QRARLAEA-VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVF 313 QR R+ EA + + L SL + ++ DA+ + G +I++GD GD FY++E+G Sbjct: 280 QRRRMYEAFLEEVPLLSSLKPYERSKIADALDAIKFPAGSSIIKEGDPGDAFYLLESGEA 339 Query: 314 DVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 + G DR K +Y+ FGELAL+ + PRAAS+ A+T + + R F+R+L Sbjct: 340 EAFKEGVDRPVK---SYQRGDYFGELALLDDQPRAASIVAKTDVKVAKLGRDGFKRLL 394 >UniRef50_Q86ZN7 Cluster: cAMP-dependent protein kinase regulatory subunit; n=23; Pezizomycotina|Rep: cAMP-dependent protein kinase regulatory subunit - Trichoderma atroviride (Hypocrea atroviridis) Length = 462 Score = 130 bits (314), Expect = 2e-29 Identities = 79/171 (46%), Positives = 100/171 (58%), Gaps = 10/171 (5%) Frame = +2 Query: 32 ARFN-NRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQ 208 A++N +RR SV AE+ P D D P K+ Q RL A+ G LF LD +Q Sbjct: 155 AQYNFSRRTSVSAESLKPSADGFDNWTPPYTDKTPEQVERLKYAIEGNFLFSHLDDEQSA 214 Query: 209 QVLDAMFEKRSEP-GEYVIRQGDDGDNFYVIENGVFDVLVT-------GDDRVEKVVHTY 364 Q+L A+ EK G VI QGD GD FYV+E G FDV V G D + V T Sbjct: 215 QILGALVEKPIPARGIKVISQGDAGDYFYVVERGSFDVYVNDCGFIEPGPDGLGNKVGTI 274 Query: 365 EGSGSFGELALMYNMPRAAS-VRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 + GSFGELALMYN PRAA+ + A+ + LWA+DR TFRRIL++S F +R+ Sbjct: 275 QAGGSFGELALMYNAPRAATIISAEGSCTLWALDRVTFRRILMESTFARRR 325 Score = 61.7 bits (143), Expect = 1e-08 Identities = 35/118 (29%), Positives = 65/118 (55%) Frame = +2 Query: 134 AQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVF 313 A+R + + + SL + ++ DA+ ++ PG+ +I +GD G +FY++E+G Sbjct: 322 ARRRMYENFLEEVPILSSLTPYERSKISDALETQKFAPGDVIIHEGDPGHSFYLLESGEA 381 Query: 314 DVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 + E+ V +Y+ FGELAL+ + PRAASV A + + + ++ F+R+L Sbjct: 382 AAF-----KGEEQVLSYKKGDFFGELALLNDAPRAASVIATSDVKVATLGKNAFQRLL 434 >UniRef50_P10644 Cluster: cAMP-dependent protein kinase type I-alpha regulatory subunit; n=105; Eumetazoa|Rep: cAMP-dependent protein kinase type I-alpha regulatory subunit - Homo sapiens (Human) Length = 381 Score = 126 bits (305), Expect = 2e-28 Identities = 73/163 (44%), Positives = 95/163 (58%) Frame = +2 Query: 26 PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQM 205 PV + RR ++ AE Y E+D+ V PK A LA+A+ +LF LD + Sbjct: 89 PVVKGRRRRGAISAEVYT--EEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNER 146 Query: 206 QQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFG 385 + DAMF GE VI+QGD+GDNFYVI+ G DV V E EG GSFG Sbjct: 147 SDIFDAMFSVSFIAGETVIQQGDEGDNFYVIDQGETDVYVNN----EWATSVGEG-GSFG 201 Query: 386 ELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 ELAL+Y PRAA+V+A+T LW +DR ++RRIL+ S +KRK Sbjct: 202 ELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRK 244 Score = 61.7 bits (143), Expect = 1e-08 Identities = 40/118 (33%), Positives = 60/118 (50%), Gaps = 1/118 (0%) Frame = +2 Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316 +R E + + + SLD + V DA+ + E G+ ++ QG+ GD F++I G Sbjct: 242 KRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAA 301 Query: 317 VLVTGDDRVEKV-VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 VL + E V V S FGE+AL+ N PRAA+V A+ +DR F R+L Sbjct: 302 VLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVL 359 >UniRef50_Q4TGP1 Cluster: Chromosome undetermined SCAF3574, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF3574, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 235 Score = 124 bits (299), Expect = 1e-27 Identities = 60/117 (51%), Positives = 80/117 (68%), Gaps = 1/117 (0%) Frame = +2 Query: 41 NNRRKSVFAETYDPEEDDSDEGAPAVF-PKSDAQRARLAEAVRGILLFRSLDAQQMQQVL 217 +NRR SV AE Y+P+ED+ ++ P V PK+D QR RL +A + ILLF++LD +Q ++L Sbjct: 89 SNRRVSVCAEAYNPDEDEDEDAEPRVVNPKTDEQRRRLKDACKHILLFKTLDQEQFSEIL 148 Query: 218 DAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGE 388 DAMFE +P +++I QGDDGDNFYVIE G FD+ V D V Y+ GSFGE Sbjct: 149 DAMFEVLVKPQQHIIDQGDDGDNFYVIEKGTFDIFVQ-KDGASLCVGKYDNKGSFGE 204 >UniRef50_P07278 Cluster: cAMP-dependent protein kinase regulatory subunit; n=6; Saccharomycetales|Rep: cAMP-dependent protein kinase regulatory subunit - Saccharomyces cerevisiae (Baker's yeast) Length = 416 Score = 121 bits (292), Expect = 9e-27 Identities = 76/166 (45%), Positives = 100/166 (60%), Gaps = 3/166 (1%) Frame = +2 Query: 23 PPVA-RFN-NRRKSVFAETYDPEEDDSDEGAPAVFP-KSDAQRARLAEAVRGILLFRSLD 193 PP+ FN RR SV ET P ++ D+ P + KS+ Q RL +++R LF LD Sbjct: 132 PPLPMHFNAQRRTSVSGETLQP--NNFDDWTPDHYKEKSEQQLQRLEKSIRNNFLFNKLD 189 Query: 194 AQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGS 373 + + V++ + EK G +I+QGD GD FYV+E G D V + KV + GS Sbjct: 190 SDSKRLVINCLEEKSVPKGATIIKQGDQGDYFYVVEKGTVDFYVNDN----KVNSSGPGS 245 Query: 374 GSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511 SFGELALMYN PRAA+V A + LWA+DR TFR+ILL S+FKKR Sbjct: 246 -SFGELALMYNSPRAATVVATSDCLLWALDRLTFRKILLGSSFKKR 290 Score = 69.7 bits (163), Expect = 4e-11 Identities = 39/118 (33%), Positives = 66/118 (55%), Gaps = 1/118 (0%) Frame = +2 Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316 +R + ++ + + +SL ++ DA+ K +PGE +IR+GD G+NFY+IE G D Sbjct: 289 KRLMYDDLLKSMPVLKSLTTYDRAKLADALDTKIYQPGETIIREGDQGENFYLIEYGAVD 348 Query: 317 VLVTGDDRVEKVV-HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 V G + K+ H Y FGE+AL+ ++PR A+V A + + + F+R+L Sbjct: 349 VSKKGQGVINKLKDHDY-----FGEVALLNDLPRQATVTATKRTKVATLGKSGFQRLL 401 >UniRef50_Q9HEW1 Cluster: cAMP-dependent protein kinase regulatory subunit; n=8; Saccharomycetales|Rep: cAMP-dependent protein kinase regulatory subunit - Candida albicans (Yeast) Length = 459 Score = 121 bits (292), Expect = 9e-27 Identities = 74/164 (45%), Positives = 92/164 (56%) Frame = +2 Query: 20 KPPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQ 199 K PVA NRR SV AE +P + D P V S + LA ++ LF+ LDA Sbjct: 168 KIPVAFNANRRTSVSAEALNPAKLKLDSWKPPVNNLSITEEETLANNLKNNFLFKQLDAN 227 Query: 200 QMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS 379 + V+ A+ +K +I+QGD+GD FY+IE G D V KV + EGS S Sbjct: 228 SKKTVIAALQQKSFAKDTVIIQQGDEGDFFYIIETGTVDFYVND----AKVSSSSEGS-S 282 Query: 380 FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511 FGELALMYN PRAA+ A T WA+DR TFRRILL+ F KR Sbjct: 283 FGELALMYNSPRAATAVAATDVVCWALDRLTFRRILLEGTFNKR 326 Score = 54.4 bits (125), Expect = 1e-06 Identities = 31/117 (26%), Positives = 64/117 (54%) Frame = +2 Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316 +R + ++ I + +SL ++ DA+ + G+ ++ +G+ G+NFY+IE+G Sbjct: 325 KRLMYEDFLKDIEVLKSLSDHARSKLADALSTEMYHKGDKIVTEGEQGENFYLIESGNCQ 384 Query: 317 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 V ++++ + +G FGELAL+ ++PR A+V A + + + F+R+L Sbjct: 385 VY---NEKLGNIKQLTKGD-YFGELALIKDLPRQATVEALDNVIVATLGKSGFQRLL 437 >UniRef50_Q9HFV9 Cluster: CAMP dependent protein kinase regulatory subunit; n=3; Filobasidiella neoformans|Rep: CAMP dependent protein kinase regulatory subunit - Cryptococcus neoformans var. neoformans Length = 482 Score = 120 bits (289), Expect = 2e-26 Identities = 74/160 (46%), Positives = 98/160 (61%), Gaps = 16/160 (10%) Frame = +2 Query: 83 EEDDS----DEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPG 250 EED++ + G P VFPKS+ Q AR+ +A++ LFR+LD +Q VL AM E + + G Sbjct: 185 EEDENTVNLNSGTP-VFPKSEEQLARIRQAIKPNFLFRNLDDEQEADVLAAMKEVKVDAG 243 Query: 251 EYVIRQGDDGDNFYVIENGVFDVLVTGDDRV------------EKVVHTYEGSGSFGELA 394 E VI QG GD FY++ENG DV V + +V +KV EGS SFGELA Sbjct: 244 EVVIEQGAAGDFFYIVENGRLDVFVNKEGQVLDLEKGDRQGLGKKVAECSEGS-SFGELA 302 Query: 395 LMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 LM+N PRAAS+ + T LWA+DR +FR ILL +KR+ Sbjct: 303 LMHNAPRAASIISLTPCTLWALDRVSFRTILLDHTSRKRR 342 Score = 64.1 bits (149), Expect = 2e-09 Identities = 41/121 (33%), Positives = 64/121 (52%), Gaps = 3/121 (2%) Frame = +2 Query: 134 AQRARLAEA-VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGV 310 +++ RL E+ + + + SL Q+ ++ D + + GE VIRQGD GD F++IE+G Sbjct: 338 SRKRRLYESFLSEVPILASLQPQERAKIADVLESRTYNEGEDVIRQGDAGDEFFLIESGN 397 Query: 311 FDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGAL--WAMDRHTFRRI 484 + T +D VV FGELAL+ RAA++RA+ L A+ F R+ Sbjct: 398 AMAIKTDEDGNASVVKHLGQGEYFGELALLNRRTRAATIRAEGPDKLRVAALGEQAFTRL 457 Query: 485 L 487 L Sbjct: 458 L 458 >UniRef50_Q240X5 Cluster: Cyclic nucleotide-binding domain containing protein; n=2; Eukaryota|Rep: Cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 414 Score = 115 bits (277), Expect = 6e-25 Identities = 59/172 (34%), Positives = 99/172 (57%), Gaps = 1/172 (0%) Frame = +2 Query: 2 EXYFVKKPPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLF 181 E + +++ + R SV AE Y + P V K + Q+ R+ + +F Sbjct: 104 EHHIIQQQQKNKGKGMRASVSAEAYG-SFNKKGSYVPKVVHKEEEQKKRIEHRLMQAFMF 162 Query: 182 RSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT-GDDRVEKVVH 358 ++LD ++ + V++AM E + PG+++I+QG+DGDN YV++ G D D + + Sbjct: 163 QALDEKEREIVVNAMTEVKFSPGDWIIKQGEDGDNLYVVDQGELDCYKKFSKDAEDTYLK 222 Query: 359 TYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 TY +FGELAL+YN PRAAS++A+T L+++DR F I+ +SA K+R+ Sbjct: 223 TYMPGEAFGELALLYNAPRAASIKAKTDSILFSLDRECFNNIVKESAIKRRE 274 Score = 77.4 bits (182), Expect = 2e-13 Identities = 42/117 (35%), Positives = 68/117 (58%) Frame = +2 Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316 +R R + ++ + L S+D + + D + + + + GEYVIR+G++G FY+IE G Sbjct: 272 RRERFEQTLQKVELLDSMDPYERVHLADGIRDIKHKAGEYVIREGEEGKYFYMIEEGQLK 331 Query: 317 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 T ++ E V+ Y+ FGELAL+ N+PR A+V A T L +D TF+R+L Sbjct: 332 ATKT-ENGHEVQVYEYKEGDYFGELALVKNIPRQANVIATTDVKLMYLDHDTFKRLL 387 >UniRef50_Q5DAR5 Cluster: SJCHGC05163 protein; n=1; Schistosoma japonicum|Rep: SJCHGC05163 protein - Schistosoma japonicum (Blood fluke) Length = 172 Score = 113 bits (272), Expect = 2e-24 Identities = 54/95 (56%), Positives = 73/95 (76%), Gaps = 2/95 (2%) Frame = +2 Query: 47 RRKSVFAETYDPEED--DSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLD 220 RR+SV AE++DPE+D D++E ++PKSD+QRARL AV+ ILLFR LD +Q +V+D Sbjct: 53 RRQSVAAESFDPEKDSDDNNEEERQIYPKSDSQRARLTNAVKEILLFRCLDEEQKSKVID 112 Query: 221 AMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV 325 AM E + + G+ VI QGDDGDNFYVIE+G +D+ V Sbjct: 113 AMQEMKVKQGDVVITQGDDGDNFYVIESGTYDIYV 147 >UniRef50_Q9BMY7 Cluster: CAMP-dependent protein kinase regulatory subunit; n=1; Toxoplasma gondii|Rep: CAMP-dependent protein kinase regulatory subunit - Toxoplasma gondii Length = 385 Score = 111 bits (268), Expect = 7e-24 Identities = 63/156 (40%), Positives = 89/156 (57%), Gaps = 1/156 (0%) Frame = +2 Query: 50 RKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMF 229 R+SV AE Y AP V+PK+ Q+ R+ + + LF SLD + ++ V++A Sbjct: 92 RQSVSAEAYGEWNKRKKFVAP-VYPKTAEQKERITKVIESSFLFSSLDIEDLETVINAFQ 150 Query: 230 EKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT-GDDRVEKVVHTYEGSGSFGELALMYN 406 E + G +IRQGDDGD Y+IE G DV+ ++ K + +FGELALMYN Sbjct: 151 EVSVKKGTVIIRQGDDGDRLYLIETGEVDVMKKFPGEKENKFLCKMHPGDAFGELALMYN 210 Query: 407 MPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 PRAA+V A LWA+DR +F I+ +A KKR+ Sbjct: 211 APRAATVIAADDMLLWALDRDSFTNIVRDAAAKKRE 246 Score = 73.7 bits (173), Expect = 2e-12 Identities = 40/132 (30%), Positives = 73/132 (55%) Frame = +2 Query: 92 DSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQG 271 D D V + +R E+++ + + +D + ++ DA+ E G+ +I++G Sbjct: 229 DRDSFTNIVRDAAAKKREIFEESLKEVRILEDMDPYERSKLSDALRTATYEDGDVIIKEG 288 Query: 272 DDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGAL 451 + GD FY++ G + + + +KVV Y+ G FGELAL+ + PRAA+V A++ + Sbjct: 289 ETGDTFYILLEGAAEAI-----KNDKVVMEYKKGGFFGELALLKDQPRAATVVAKSHVQV 343 Query: 452 WAMDRHTFRRIL 487 MDR +F+R+L Sbjct: 344 AYMDRKSFKRLL 355 >UniRef50_Q22NC5 Cluster: Cyclic nucleotide-binding domain containing protein; n=5; Oligohymenophorea|Rep: Cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 381 Score = 111 bits (268), Expect = 7e-24 Identities = 60/155 (38%), Positives = 95/155 (61%) Frame = +2 Query: 50 RKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMF 229 R SV AE Y S A + PK+ Q R+ + + +F+SLD + + V+ AM Sbjct: 94 RTSVSAEAYGQYNQKSAFVAKNI-PKNANQVLRIKQRLSQAFMFQSLDENEQRVVIGAME 152 Query: 230 EKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNM 409 EK+ + GE +I+QGDDGD YV+++G+ D ++ + ++ TY+ +FGELAL+YN Sbjct: 153 EKKFKAGETIIKQGDDGDELYVVDSGLLDCYKEKANQEKILLKTYKEGEAFGELALLYNA 212 Query: 410 PRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 PRAA++ A+T L+++DR TF I+ +A KKR+ Sbjct: 213 PRAATIIAKTDCILFSLDRPTFNHIVKDAAAKKRE 247 Score = 68.5 bits (160), Expect = 8e-11 Identities = 32/96 (33%), Positives = 62/96 (64%), Gaps = 3/96 (3%) Frame = +2 Query: 209 QVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVF---DVLVTGDDRVEKVVHTYEGSGS 379 Q+ DA+ + G+Y++++G++G++F+++E G+ V+ G V+ V+ Y+ Sbjct: 269 QIADALHSHKFSKGDYIVKEGENGNSFFILEEGIAVATKVMQAGQAPVK--VYEYKSGDY 326 Query: 380 FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 FGE+AL+ N RAA+V A++ + +MDR +F+R+L Sbjct: 327 FGEIALLKNQTRAANVIAESDCTVVSMDRESFKRLL 362 >UniRef50_A0DZ01 Cluster: Chromosome undetermined scaffold_7, whole genome shotgun sequence; n=7; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_7, whole genome shotgun sequence - Paramecium tetraurelia Length = 377 Score = 111 bits (267), Expect = 9e-24 Identities = 61/167 (36%), Positives = 96/167 (57%), Gaps = 1/167 (0%) Frame = +2 Query: 17 KKPPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDA 196 K+P AR +R S+ AE Y + + + P V K+ Q+ ++ + + +F SLD Sbjct: 73 KRPAAAR--KQRASISAEAYG-QYNRKESFQPRVIVKTQQQKEKIGKRLEQSFMFASLDQ 129 Query: 197 QQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT-GDDRVEKVVHTYEGS 373 ++ V+DAM E+ ++VI+QGD+GDN YV++ G + D K + Y Sbjct: 130 REKDIVIDAMEERSYNAEDWVIQQGDNGDNLYVVDQGELNCYKRFTKDGENKFLKVYYPG 189 Query: 374 GSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 SFGELAL+YN PRAAS++ +T L+A+DR TF I+ +A +KR+ Sbjct: 190 ESFGELALLYNAPRAASIQCKTNSILFALDRQTFNHIVKDAAMRKRE 236 Score = 80.2 bits (189), Expect = 3e-14 Identities = 45/120 (37%), Positives = 70/120 (58%), Gaps = 3/120 (2%) Frame = +2 Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG--- 307 +R + ++ I L +D + V DA+ + G+YVIR+G+ GD FY+IE+G Sbjct: 234 KREKYVNVLKQIELLSMMDPYERSHVADAIRSANFQNGDYVIREGEQGDIFYMIEDGDLI 293 Query: 308 VFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 LV G + V+ V Y+ FGELAL+ ++PR A++ AQT L +DRH+F+R+L Sbjct: 294 ATKTLVQGQEPVK--VFQYKTGDYFGELALLKDIPRQANIVAQTEVKLIYLDRHSFKRML 351 >UniRef50_Q7KQK0 Cluster: CAMP-dependent protein kinase regulatory subunit, putative; n=7; Plasmodium|Rep: CAMP-dependent protein kinase regulatory subunit, putative - Plasmodium falciparum (isolate 3D7) Length = 441 Score = 109 bits (263), Expect = 3e-23 Identities = 56/156 (35%), Positives = 88/156 (56%) Frame = +2 Query: 47 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226 +R SV AE Y D P V+ K + ++A++ EA+ LF L+ ++ + +++A Sbjct: 146 KRLSVSAEAYGDWNKKIDNFIPKVYKKDEKEKAKIREALNESFLFNHLNKKEFEIIVNAF 205 Query: 227 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYN 406 F+K E G +I +GD GD YVI+ G ++ T ++ ++V+ + FGELAL+YN Sbjct: 206 FDKNVEKGVNIINEGDYGDLLYVIDQGEVEIYKTKENNKKEVLTVLKSKDVFGELALLYN 265 Query: 407 MPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 RAA+ A T LWA+DR +F I+ KKRK Sbjct: 266 SKRAATATALTKCHLWALDRESFTYIIKDMVAKKRK 301 Score = 71.7 bits (168), Expect = 9e-12 Identities = 36/117 (30%), Positives = 69/117 (58%) Frame = +2 Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316 +R + + + + + +D + +V D + K GE +I++G++GD F+++ +G + Sbjct: 299 KRKMYEDILSHVNILKDMDPYERCKVADCLKSKSYNDGEIIIKEGEEGDTFFILIDG--N 356 Query: 317 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 + + D+ KV+ TY FGELAL+ N PRAA+++AQ + +DR +F+R+L Sbjct: 357 AVASKDN---KVIKTYTKGDYFGELALLKNKPRAATIKAQNFCQVVYLDRKSFKRLL 410 >UniRef50_Q3SED2 Cluster: CAMP-dependent protein kinase, regulatory subunit 3-1; n=5; Paramecium tetraurelia|Rep: CAMP-dependent protein kinase, regulatory subunit 3-1 - Paramecium tetraurelia Length = 369 Score = 109 bits (262), Expect = 4e-23 Identities = 62/157 (39%), Positives = 94/157 (59%), Gaps = 2/157 (1%) Frame = +2 Query: 50 RKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMF 229 R +V AE Y + + ++ P KS+ Q R+ + + +F++LD + + VL AM Sbjct: 84 RAAVSAEVYG-DYNKKEDFKPRFIQKSEGQIERIKKRILNSFMFQALDEKDLNIVLGAMD 142 Query: 230 EKRSEPGEYVIRQGDDGDNFYVIENGVFDVL--VTGDDRVEKVVHTYEGSGSFGELALMY 403 EK+ + G+ VI+QGDDG+ YVI+ G + TG + EK++ TY SFGELAL+Y Sbjct: 143 EKKFQVGDEVIKQGDDGNELYVIDEGRLECYKKFTGFEE-EKLLKTYIPGESFGELALLY 201 Query: 404 NMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 N PRAA+++A +A+DR TF I+ SA KKR+ Sbjct: 202 NAPRAATIKAIEEVTTFALDRETFNNIVKFSAIKKRE 238 Score = 70.1 bits (164), Expect = 3e-11 Identities = 40/117 (34%), Positives = 67/117 (57%) Frame = +2 Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316 +R ++ E + I L +S+D + Q+ D + E++ GE +I +G+ GD Y+I G + Sbjct: 236 KREQMEEILNKIDLLQSMDNYERVQLCDVLKEEKHHAGEAIINEGEIGDRIYLIIEGELE 295 Query: 317 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 G + EK V+ Y+ FGELAL+ N PR A+V A+T L D ++F+R++ Sbjct: 296 AYWKG--QTEK-VYDYKSGDYFGELALLKNTPRQATVIAKTDVVLLYCDFNSFKRLM 349 >UniRef50_UPI0001509E09 Cluster: cyclic nucleotide-binding domain containing protein; n=2; Tetrahymena thermophila SB210|Rep: cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 331 Score = 108 bits (259), Expect = 8e-23 Identities = 58/157 (36%), Positives = 93/157 (59%), Gaps = 1/157 (0%) Frame = +2 Query: 47 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226 +R SV AE Y + + P V KS + ++ + + +F LD ++ + +++AM Sbjct: 47 QRNSVSAEAYGMF-NKRENFKPIVIAKSQDTKNKIYKRINEAFMFNCLDLKEREIIVNAM 105 Query: 227 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKV-VHTYEGSGSFGELALMY 403 EKR + G+ VI+QG++G+ YVI+ G D ++ E + TY+ SFGELAL+Y Sbjct: 106 EEKRFKSGDQVIKQGEEGNYLYVIDEGQLDCFKKYQNQPEPTYLKTYQPGESFGELALLY 165 Query: 404 NMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 N PRAAS+ ++T L+A+DR TF I+ +A KKR+ Sbjct: 166 NAPRAASIVSKTPSVLFALDRETFNHIVKDAAMKKRQ 202 >UniRef50_P49605 Cluster: cAMP-dependent protein kinase regulatory subunit; n=1; Ustilago maydis|Rep: cAMP-dependent protein kinase regulatory subunit - Ustilago maydis (Smut fungus) Length = 525 Score = 108 bits (259), Expect = 8e-23 Identities = 74/180 (41%), Positives = 102/180 (56%), Gaps = 17/180 (9%) Frame = +2 Query: 23 PPVARFN-NRRKSVFAETYDPEEDDSD-EGAP---AVFPKSDAQRARLAEAVRGILLFRS 187 PP FN RR SV AE+ P +++ +G+P V PKS+ Q R+ ++ LLFR+ Sbjct: 160 PPT--FNLGRRTSVSAESMAPSAANAESDGSPLPKTVIPKSEEQMQRIRGSIGNNLLFRN 217 Query: 188 LDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRV-------- 343 L+ Q + VL AM E + + VI QG GD FYV+E G DV V D V Sbjct: 218 LEQDQYRDVLLAMKEVKVDANVTVIEQGAQGDYFYVVEFGTLDVYVRSPDAVSEGAPSAS 277 Query: 344 ----EKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511 +K V +Y SFGELAL+Y PRAA+V + +A LWA+DR TFR IL+++ ++R Sbjct: 278 ALLGDKKV-SYGPGSSFGELALLYAQPRAATVLSTSACTLWALDRITFRSILMETNSRRR 336 Score = 56.4 bits (130), Expect = 4e-07 Identities = 36/102 (35%), Positives = 53/102 (51%) Frame = +2 Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316 +RA + + + LF L A + ++ D++ + GE VI QG+ G F++I G + Sbjct: 335 RRALYEKFLMDVPLFERLSAAERAKISDSLELREYSRGEAVISQGERGSEFFIIVEGDAE 394 Query: 317 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTA 442 V T E+VV FGELAL+ N PRAA+V A A Sbjct: 395 VRKTKQGG-EEVVGKLSRGDYFGELALLNNAPRAATVAAAGA 435 >UniRef50_P05987 Cluster: cAMP-dependent protein kinase regulatory subunit; n=2; Dictyostelium discoideum|Rep: cAMP-dependent protein kinase regulatory subunit - Dictyostelium discoideum (Slime mold) Length = 327 Score = 107 bits (256), Expect = 2e-22 Identities = 63/159 (39%), Positives = 93/159 (58%), Gaps = 1/159 (0%) Frame = +2 Query: 41 NNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLD 220 N RK A + +P D P + PK+ + RL +A+ ++F L+ ++ V Sbjct: 22 NITRKRRGAISSEPLGDKPATPLPNI-PKTVETQQRLEQALSNNIMFSHLEEEERNVVFL 80 Query: 221 AMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV-TGDDRVEKVVHTYEGSGSFGELAL 397 AM E + G+ +I+QGD+GD FYVI++G+ D+ V V+ +EG GSFGELAL Sbjct: 81 AMVEVLYKAGDIIIKQGDEGDLFYVIDSGICDIYVCQNGGSPTLVMEVFEG-GSFGELAL 139 Query: 398 MYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 +Y PRAA+V A+T LWA++ T+RRIL+ KKRK Sbjct: 140 IYGSPRAATVIARTDVRLWALNGATYRRILMDQTIKKRK 178 Score = 66.5 bits (155), Expect = 3e-10 Identities = 39/119 (32%), Positives = 58/119 (48%), Gaps = 3/119 (2%) Frame = +2 Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG--- 307 +R E + + + R +D + + DA+ + GE ++RQGD GD FY+I G Sbjct: 176 KRKLYEEFLEKVSILRHIDKYERVSLADALEPVNFQDGEVIVRQGDPGDRFYIIVEGKVV 235 Query: 308 VFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484 V V GD VV S FGE+AL+ + PRAA+V + +DR F R+ Sbjct: 236 VTQETVPGDHSTSHVVSELHPSDYFGEIALLTDRPRAATVTSIGYTKCVELDRQRFNRL 294 >UniRef50_Q6C2X0 Cluster: cAMP-dependent protein kinase regulatory subunit; n=1; Yarrowia lipolytica|Rep: cAMP-dependent protein kinase regulatory subunit - Yarrowia lipolytica (Candida lipolytica) Length = 375 Score = 105 bits (252), Expect = 6e-22 Identities = 67/162 (41%), Positives = 91/162 (56%) Frame = +2 Query: 26 PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQM 205 P A F RR SV AE+ P A S Q L ++V LF +LD + Sbjct: 94 PAAPFT-RRTSVSAESIAPGAFAGAASGVASNNLSAEQLESLYKSVSHNFLFGNLDEEAC 152 Query: 206 QQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFG 385 + VL ++ EK+ + GE +I QGD+GD FY++E+G + + G KV + GS SFG Sbjct: 153 RSVLQSLQEKKCDSGEKIITQGDEGDYFYIVESGAVEFIKDG----VKVNSSGPGS-SFG 207 Query: 386 ELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511 ELALMYN PRAA+V A LW++DR TFR+ILL ++R Sbjct: 208 ELALMYNAPRAATVVATQPCVLWSLDRVTFRKILLDGTHQRR 249 Score = 62.5 bits (145), Expect = 6e-09 Identities = 34/109 (31%), Positives = 63/109 (57%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340 ++ + + L + + ++ DA+ + EPG VI +G+ GD FY++E+G +V G+ Sbjct: 256 LKEVPILSDLGSYERNKLADALTSQVVEPGTAVITEGEAGDAFYLVESGEAEVTKKGE-- 313 Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 VV T + FGE+AL+ ++PR A+V A+T + + + F+R+L Sbjct: 314 -SGVVATLKQGDYFGEVALLNDLPRQATVTAKTKLKVATLGKDGFQRLL 361 >UniRef50_Q9XTM6 Cluster: CAMP-dependent protein kinase regulatory subunit; n=1; Euplotes octocarinatus|Rep: CAMP-dependent protein kinase regulatory subunit - Euplotes octocarinatus Length = 338 Score = 104 bits (250), Expect = 1e-21 Identities = 54/134 (40%), Positives = 80/134 (59%), Gaps = 1/134 (0%) Frame = +2 Query: 116 VFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYV 295 V PKSD + ++ + LF SLD + ++ V++AM K EP VI+QGDDG ++ Sbjct: 70 VVPKSDELKTQIRTRLLQSFLFSSLDDRDLEIVINAMEVKTFEPSSTVIKQGDDGAELFL 129 Query: 296 IENGVFDVL-VTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHT 472 + G D V K++ YE +FGELAL+YN PRAA+++A+T L+++DR T Sbjct: 130 VGEGTLDCFKVMKKGEEAKLIKEYEPGDAFGELALLYNAPRAATIKAKTEAVLYSLDRDT 189 Query: 473 FRRILLKSAFKKRK 514 F I+ SA KKR+ Sbjct: 190 FNLIVKDSAAKKRE 203 Score = 81.8 bits (193), Expect = 8e-15 Identities = 42/120 (35%), Positives = 72/120 (60%), Gaps = 3/120 (2%) Frame = +2 Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG--- 307 +R + + ++ + + S+ + Q+ DA+ E++ PG+YVI+QG+ GD FY+I G Sbjct: 201 KREKYEKCLKNVKVLDSVSIYERSQIADAIKEQKFNPGDYVIKQGEIGDTFYMISEGEAT 260 Query: 308 VFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 + + G E + +TY FGE+AL+ N PRAASV A+T + +DR++FRR++ Sbjct: 261 AYKIFEEGGKEEEVMKYTY--GDYFGEIALLKNEPRAASVVAKTDLIVMKLDRNSFRRMI 318 >UniRef50_A0CJF2 Cluster: Chromosome undetermined scaffold_2, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_2, whole genome shotgun sequence - Paramecium tetraurelia Length = 585 Score = 104 bits (250), Expect = 1e-21 Identities = 48/133 (36%), Positives = 82/133 (61%) Frame = +2 Query: 116 VFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYV 295 V PK+ Q++R+ + + LF+ L+ QQ + V +AM EK+ + E +I+QGDDGD ++ Sbjct: 317 VIPKNKDQKSRVQKKINTCYLFKHLNDQQKEIVANAMEEKKYKATETIIKQGDDGDQLFL 376 Query: 296 IENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTF 475 ++ G+ D G +K++ +Y+ FGE+AL+YN RAA++ A T LWA+D+ TF Sbjct: 377 VDQGLLDCQKRGKQIEDKIIKSYQPGDFFGEMALLYNEKRAATIIAFTECVLWALDKETF 436 Query: 476 RRILLKSAFKKRK 514 + + +KR+ Sbjct: 437 DTFIKQPVLEKRQ 449 Score = 59.3 bits (137), Expect = 5e-08 Identities = 32/106 (30%), Positives = 56/106 (52%), Gaps = 2/106 (1%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTG--DDRVEK 349 + + +D QQ+ DA++ + E V +Q D GD FY+I+ G L G D+ E+ Sbjct: 460 ILQQIDPYLRQQIADALYVVSFKADEVVFKQKDKGDYFYLIQEGQLKALKKGDEDEDEEQ 519 Query: 350 VVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 V + FGELA++ + R A++ +T L +D+ +F ++L Sbjct: 520 CVFEFGEFDYFGELAMLKEINRQATIVCETDCILLGLDKQSFTKLL 565 >UniRef50_A0BRC9 Cluster: Chromosome undetermined scaffold_122, whole genome shotgun sequence; n=4; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_122, whole genome shotgun sequence - Paramecium tetraurelia Length = 374 Score = 104 bits (249), Expect = 1e-21 Identities = 56/164 (34%), Positives = 90/164 (54%), Gaps = 2/164 (1%) Frame = +2 Query: 26 PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQM 205 PV R SV AE + + + P V PK++ Q+ ++ E + + +F++L + Sbjct: 78 PVKNAKTFRSSVSAEVFGVH-NKKENFIPRVIPKTEEQKQQILEKLMKVFMFQALGQHEQ 136 Query: 206 QQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL--VTGDDRVEKVVHTYEGSGS 379 + V++AM EK ++VI QGDDG Y++ +G D + D K + Y+ Sbjct: 137 EIVVNAMEEKHYTKDDWVITQGDDGAELYIVFSGELDCFRKMKPTDPEPKFLKKYKPGDM 196 Query: 380 FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511 FGEL+L+YN PRAAS++A+ L+A+DR TF I+ + KKR Sbjct: 197 FGELSLLYNSPRAASIQAKEDSVLFALDRSTFNNIVKDATIKKR 240 Score = 72.5 bits (170), Expect = 5e-12 Identities = 34/117 (29%), Positives = 69/117 (58%) Frame = +2 Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316 +R + E + + L +S++A + Q+ D + E+ + GE +I++G++GD FY++ G Sbjct: 239 KRLQYEEVLSKVELLQSMEAYEKTQICDGLKEQTYQKGEVIIQEGEEGDKFYMVAEGTLA 298 Query: 317 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 + + +V+ Y+ FGELAL++ +PR A++ A+T + +D ++F R+L Sbjct: 299 AYKDNNGQQVEVLR-YQPGDYFGELALIHKLPRQATIIAETQCVVVYLDSNSFLRLL 354 >UniRef50_Q8TF77 Cluster: cAMP-dependent protein kinase regulatory subunit; n=4; Mucoraceae|Rep: cAMP-dependent protein kinase regulatory subunit - Rhizomucor racemosus (Mucor circinelloides f. lusitanicus) Length = 427 Score = 104 bits (249), Expect = 1e-21 Identities = 55/131 (41%), Positives = 78/131 (59%) Frame = +2 Query: 122 PKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIE 301 P+ R+ ++ LFR+LD +Q V++AM EKR G VI QG GD FYV+E Sbjct: 167 PQISGTSERIKVSISNNFLFRNLDEEQYLDVVNAMSEKRVVKGTTVIEQGSVGDFFYVVE 226 Query: 302 NGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481 +G D + G ++V YE GSFGELALMYN PRAA++ + LWA+DR+T Sbjct: 227 SGTLDCFI-GQNKVTN----YEAGGSFGELALMYNAPRAATIITTSDSVLWALDRNTSAP 281 Query: 482 ILLKSAFKKRK 514 L+++ +KR+ Sbjct: 282 SLMENTSRKRR 292 Score = 74.9 bits (176), Expect = 1e-12 Identities = 40/132 (30%), Positives = 74/132 (56%) Frame = +2 Query: 92 DSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQG 271 D + AP++ + +R + ++L +SL++ + ++ DA+ E G+ V++QG Sbjct: 275 DRNTSAPSLMENTSRKRRMYEYFLSEVVLLKSLESYEQHKIADALESVYFEDGQEVVKQG 334 Query: 272 DDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGAL 451 D GD FY+IE+G +++ ++ V++ V+ E FGELAL+ + PRAA+V A Sbjct: 335 DVGDQFYIIESGE-AIVLKEENGVQQQVNQLERGSYFGELALLNDAPRAATVVAHGRLKC 393 Query: 452 WAMDRHTFRRIL 487 + + F R+L Sbjct: 394 ATLGKKAFTRLL 405 >UniRef50_A0BNE3 Cluster: Chromosome undetermined scaffold_118, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_118, whole genome shotgun sequence - Paramecium tetraurelia Length = 374 Score = 103 bits (247), Expect = 2e-21 Identities = 59/157 (37%), Positives = 90/157 (57%), Gaps = 2/157 (1%) Frame = +2 Query: 50 RKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMF 229 R SV AE Y ++ P + KS Q ++ E + +F LD ++ V++AM Sbjct: 87 RASVSAEVYGIYNKKTNF-KPKIVAKSHLQIQKIKEKLAQSFMFSELDEHDLRIVINAME 145 Query: 230 EKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT--GDDRVEKVVHTYEGSGSFGELALMY 403 + + G+ +IRQGDDGDN Y+++ G D T G D V + TY+ SFGELAL+Y Sbjct: 146 VIQCKKGDIIIRQGDDGDNLYIVDEGTLDCSRTKAGQDSVH--LKTYKPGESFGELALLY 203 Query: 404 NMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 N PRAA++ A+ L+++DR TF I+ +A +KR+ Sbjct: 204 NSPRAATIVAEENCVLFSLDRGTFNHIVKDAAIRKRE 240 Score = 77.4 bits (182), Expect = 2e-13 Identities = 40/118 (33%), Positives = 65/118 (55%), Gaps = 1/118 (0%) Frame = +2 Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG-VF 313 +R R + + L + LD Q+ DA+ + G+Y++++GD+GD FY +E G Sbjct: 238 KRERYEYFLAHVELLQELDPYSRSQIADALKSRNFNIGDYIVKEGDEGDIFYFLEKGEAV 297 Query: 314 DVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 V + + V+ Y+ FGE+AL+ PRAASV A+T + +DR TF+R+L Sbjct: 298 ATKVLNQSQPAQEVYFYKEGDYFGEIALLRQAPRAASVIAETPCTVVYLDRETFKRLL 355 >UniRef50_A2R984 Cluster: Catalytic activity: ATP + a protein <=> ADP + a phosphoprotein; n=1; Aspergillus niger|Rep: Catalytic activity: ATP + a protein <=> ADP + a phosphoprotein - Aspergillus niger Length = 417 Score = 103 bits (247), Expect = 2e-21 Identities = 65/165 (39%), Positives = 92/165 (55%), Gaps = 9/165 (5%) Frame = +2 Query: 47 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226 RR SV AE++ P + + F ++ Q RL AV+ + LF +LD +Q Q+L A Sbjct: 79 RRNSVSAESFVPGQQSLPSTS---FDMTEEQAHRLVRAVKEVFLFSALDKEQYAQLLSAF 135 Query: 227 FEKRSE-PGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKV---VHTYEGSGS----F 382 K G VI QGD GDNFY++E G FD+ +T + + T GS F Sbjct: 136 VGKAVPIKGTNVITQGDIGDNFYIVEKGSFDIYITLASTPQPTTPSIGTKHGSAHPGDFF 195 Query: 383 GELALMYNMPRAASVRAQTAGA-LWAMDRHTFRRILLKSAFKKRK 514 GELAL+YN PRAA++ + LWA+D +FRRI+ +SAF +R+ Sbjct: 196 GELALLYNAPRAATIISTEPDCHLWAIDGVSFRRIMAESAFARRR 240 Score = 58.0 bits (134), Expect = 1e-07 Identities = 39/109 (35%), Positives = 56/109 (51%), Gaps = 5/109 (4%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKV- 352 L L +Q ++ +A+ +R G+ +I QGD G +F++ LV+G+ R KV Sbjct: 251 LLAGLSGRQRSRIAEALQTRRYCAGDTIILQGDLGSDFFL--------LVSGEARAYKVG 302 Query: 353 ----VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 V TY G FGE A N PRAAS+ A T + +DR F R+L Sbjct: 303 FVGSVKTYTSGGWFGERAFRKNAPRAASIMAITDVVVAVLDRDAFARLL 351 >UniRef50_Q4UEK0 Cluster: CAMP-dependent protein kinase regulatory subunit, putative; n=2; Theileria|Rep: CAMP-dependent protein kinase regulatory subunit, putative - Theileria annulata Length = 313 Score = 101 bits (243), Expect = 7e-21 Identities = 54/155 (34%), Positives = 85/155 (54%) Frame = +2 Query: 50 RKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMF 229 R SV AE + S P + K+ ++A++ E ++ LF +++ + ++ A Sbjct: 21 RLSVSAEVFGDNHSKSKVVIPN-YEKTPQEQAKIMEMIKRCFLFSGVNSSGLDLLVKAFD 79 Query: 230 EKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNM 409 K + PG+ +I+QGDDGD Y+IE+G +V E+ + FGELALMYN Sbjct: 80 FKTANPGDVLIKQGDDGDKLYLIESGTVEVTRKNATGQEEFLCNLTAGDYFGELALMYNS 139 Query: 410 PRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 PRAA+V A+T LW +DR TF ++ + KKR+ Sbjct: 140 PRAATVVAKTEMHLWTLDRTTFNHVVRMAVIKKRE 174 Score = 46.4 bits (105), Expect = 4e-04 Identities = 28/104 (26%), Positives = 53/104 (50%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355 LF+ ++ ++ DA+ E+ E E VI+QG+ G + +++ G + V K+V Sbjct: 185 LFKKVNPYDRCRLADALVERTFED-ETVIKQGEPGSSLFMVLEGQAESFVEN-----KLV 238 Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 +Y FGE+ + PRA++V+A+ ++R F +L Sbjct: 239 KSYNPGDYFGEIGFILKKPRASTVKAKGKCLFVELERENFINLL 282 >UniRef50_A3FPL6 Cluster: CAMP-dependent protein kinase regulatory subunit; n=2; Cryptosporidium|Rep: CAMP-dependent protein kinase regulatory subunit - Cryptosporidium parvum Iowa II Length = 345 Score = 100 bits (239), Expect = 2e-20 Identities = 58/153 (37%), Positives = 81/153 (52%) Frame = +2 Query: 50 RKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMF 229 R SV AE Y D P+ +PK+ Q R+ E + +F SLD +++ V+ A Sbjct: 58 RTSVSAEAYGAWNKMKDFTPPS-YPKTKEQEKRIREKLLESFMFTSLDDDELKTVILACV 116 Query: 230 EKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNM 409 E + +I QGD+GD Y+I+ GV + K + +FGELAL+YN Sbjct: 117 ETSVKKDTEIITQGDNGDKLYIIDQGVVECYKKTSTEPRKHLCDLNPGDAFGELALLYNC 176 Query: 410 PRAASVRAQTAGALWAMDRHTFRRILLKSAFKK 508 PRAASV A+T LWA+DR TF I+ SA K+ Sbjct: 177 PRAASVVAKTDCLLWALDRETFNHIVKGSASKR 209 Score = 64.1 bits (149), Expect = 2e-09 Identities = 36/109 (33%), Positives = 63/109 (57%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340 ++ + + +++D ++ ++ + E G+ +I+QG+ GD FY+I G L D Sbjct: 217 LKEVEILKTMDVYELNKLTMVLKSSIFEDGQEIIKQGEQGDTFYLIITGNAVAL---KDN 273 Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 VE V +Y+ FGELAL+ N PRAA+V+A+ + +DR F+R+L Sbjct: 274 VE--VMSYKRGDYFGELALLRNAPRAATVKARGRCKVAYLDRKAFKRVL 320 >UniRef50_P36600 Cluster: cAMP-dependent protein kinase regulatory subunit; n=1; Schizosaccharomyces pombe|Rep: cAMP-dependent protein kinase regulatory subunit - Schizosaccharomyces pombe (Fission yeast) Length = 412 Score = 99.1 bits (236), Expect = 5e-20 Identities = 66/168 (39%), Positives = 96/168 (57%), Gaps = 13/168 (7%) Frame = +2 Query: 47 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRA-RLAEAVRGILLFRSLDAQQMQQVLDA 223 RR+SV E+ +P + FP D + RL +V G LF++LD + +VL+A Sbjct: 101 RRQSVSTESMNPSAFALE--TKRTFPPKDPEDLKRLKRSVAGNFLFKNLDEEHYNEVLNA 158 Query: 224 MFEKR-SEPGEYVIRQGDDGDNFYVIENGVFDVL------VTGDDRVE----KVVHTYEG 370 M EKR E G VI QG GD FY++E G FDV +T ++ + + T Sbjct: 159 MTEKRIGEAGVAVIVQGAVGDYFYIVEQGEFDVYKRPELNITPEEVLSSGYGNYITTISP 218 Query: 371 SGSFGELALMYNMPRAASVRAQTA-GALWAMDRHTFRRILLKSAFKKR 511 FGELALMYN PRAASV ++T ++A+DR +FRRI+ ++A+++R Sbjct: 219 GEYFGELALMYNAPRAASVVSKTPNNVIYALDRTSFRRIVFENAYRQR 266 Score = 73.3 bits (172), Expect = 3e-12 Identities = 46/124 (37%), Positives = 67/124 (54%) Frame = +2 Query: 116 VFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYV 295 VF + QR + + + SLD Q Q++ DA+ + G VIRQGD G+ FY+ Sbjct: 258 VFENAYRQRMLYESLLEEVPILSSLDKYQRQKIADALQTVVYQAGSIVIRQGDIGNQFYL 317 Query: 296 IENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTF 475 IE+G +V+ G + VV T FGELAL++ R A+V+A+T L D+ TF Sbjct: 318 IEDGEAEVVKNG----KGVVVTLTKGDYFGELALIHETVRNATVQAKTRLKLATFDKPTF 373 Query: 476 RRIL 487 R+L Sbjct: 374 NRLL 377 >UniRef50_A7AU83 Cluster: cAMP-dependent protein kinase regulatory subunit , putative; n=1; Babesia bovis|Rep: cAMP-dependent protein kinase regulatory subunit , putative - Babesia bovis Length = 317 Score = 98.7 bits (235), Expect = 7e-20 Identities = 64/163 (39%), Positives = 86/163 (52%), Gaps = 2/163 (1%) Frame = +2 Query: 32 ARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQ 211 AR NR S+ AE + + AP V K+ Q R+ E V LF S+DA+ + Sbjct: 17 ARARNR-VSISAEVFGAYNNPDLFVAP-VHEKTPEQATRIKETVLKCFLFSSVDAKDIDT 74 Query: 212 VLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGV--FDVLVTGDDRVEKVVHTYEGSGSFG 385 ++ A G VI+QGD GD Y+IE+G F ++V + EG G FG Sbjct: 75 LVKAFESSDVSAGTKVIQQGDPGDKLYLIESGTARFTKTSAATEQVHDLGTAGEG-GCFG 133 Query: 386 ELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 ELALMYN PRA SV A+T LW++DR TF I+ + KKR+ Sbjct: 134 ELALMYNAPRACSVVAETDMKLWSLDRSTFNHIVRNAVIKKRE 176 Score = 48.4 bits (110), Expect = 1e-04 Identities = 31/112 (27%), Positives = 59/112 (52%) Frame = +2 Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316 +R + ++ + L +LD ++ DA+ EK + E +I +GD G + ++I G + Sbjct: 174 KREKYDSLLQSVALLSNLDPYDRCRLADALTEK-TFVDEDIIVEGDKGTSVFMILEGNAE 232 Query: 317 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHT 472 G K+V +Y G FGE+AL+ PRA++V+A+ + ++R + Sbjct: 233 AYCQG-----KLVKSYSEGGYFGEIALIAQTPRASTVKAKGKCVVAELERES 279 >UniRef50_Q33DX2 Cluster: Putative cyclic AMP-dependent protein kinase regulatory subunit; n=1; Schizophyllum commune|Rep: Putative cyclic AMP-dependent protein kinase regulatory subunit - Schizophyllum commune (Bracket fungus) Length = 500 Score = 69.3 bits (162), Expect(2) = 2e-19 Identities = 37/102 (36%), Positives = 54/102 (52%) Frame = +2 Query: 20 KPPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQ 199 +PP A RR SV AE+ + + +E VFPK+ Q R+ + +FR L + Sbjct: 163 QPPNASIFARRASVSAESISVDALNREETKTRVFPKTPDQMRRIQSSTANNFIFRDLTEE 222 Query: 200 QMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV 325 Q + V AM E + VIRQGDDGD FY++E+G+ + Sbjct: 223 QKRAVFLAMQEMTVDKDTVVIRQGDDGDYFYIVESGLLHCFI 264 Score = 60.9 bits (141), Expect = 2e-08 Identities = 35/102 (34%), Positives = 56/102 (54%), Gaps = 3/102 (2%) Frame = +2 Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316 +R+ + + + L SLDA + ++ DA+ + E G+ V++QG+ GD F+ +E G Sbjct: 357 RRSMYEQFLSTVTLLSSLDASERSKIADALVSRVYEDGQAVVKQGETGDTFFFVEEGEAC 416 Query: 317 VL---VTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 433 V G+D E VV + FGEL+L+ PRAA+V A Sbjct: 417 VTKRPQDGEDGEEIVVGHLKKGDYFGELSLLRLAPRAATVSA 458 Score = 48.8 bits (111), Expect(2) = 2e-19 Identities = 24/55 (43%), Positives = 33/55 (60%) Frame = +2 Query: 347 KVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511 K V Y SFGELALMY RAA+V + +LW ++R FR +++ A K+R Sbjct: 304 KRVAEYPAGTSFGELALMYGHARAATVLSVEPSSLWKIERRDFRHVVVGLAHKRR 358 >UniRef50_A0CMC2 Cluster: Chromosome undetermined scaffold_21, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_21, whole genome shotgun sequence - Paramecium tetraurelia Length = 334 Score = 95.1 bits (226), Expect = 8e-19 Identities = 57/158 (36%), Positives = 93/158 (58%), Gaps = 2/158 (1%) Frame = +2 Query: 47 RRKSVFAETYDPEEDDSDEGAPAVF-PKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDA 223 +R SV AE Y + + E A F PKS Q R+ + ++ +F +L+ ++++ V+ A Sbjct: 50 QRFSVSAEAYG--QFNKKENFKAKFIPKSKEQSERIKQRMQAGFMFSALNEKEIEIVVGA 107 Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403 M EK EYVI+QG++G+ YV++ G D + + ++ TY SFGELAL++ Sbjct: 108 MEEKIFHKAEYVIKQGEEGNVLYVVDTGELDCF-KNYGKGDVLLKTYYPGESFGELALLF 166 Query: 404 NMPRAASVRAQTAGA-LWAMDRHTFRRILLKSAFKKRK 514 PRAAS+ ++ A LW +DR TF I+ +++ KKR+ Sbjct: 167 QSPRAASIIVKSDKAILWQLDRETFNLIVKEASIKKRQ 204 Score = 32.7 bits (71), Expect = 5.1 Identities = 13/45 (28%), Positives = 25/45 (55%) Frame = +2 Query: 173 LLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG 307 LL D ++ DA+FEK+ + G+ +++QG +++E G Sbjct: 215 LLKEIKDPYDKLKMSDALFEKQYKKGDVILQQGQKSQEIFILEQG 259 >UniRef50_UPI000065ED67 Cluster: cAMP-dependent protein kinase type I-beta regulatory subunit.; n=1; Takifugu rubripes|Rep: cAMP-dependent protein kinase type I-beta regulatory subunit. - Takifugu rubripes Length = 403 Score = 88.2 bits (209), Expect = 1e-16 Identities = 46/82 (56%), Positives = 58/82 (70%) Frame = +2 Query: 269 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGA 448 GD+GDNFYVI+ G DV V G E V + EG GSFGELAL+Y PRAA+V+A+T Sbjct: 190 GDEGDNFYVIDQGEVDVYVNG----ELVTNIGEG-GSFGELALIYGTPRAATVKAKTDLK 244 Query: 449 LWAMDRHTFRRILLKSAFKKRK 514 LW +DR ++RRIL+ S +KRK Sbjct: 245 LWGIDRDSYRRILMGSTLRKRK 266 Score = 64.9 bits (151), Expect = 1e-09 Identities = 41/118 (34%), Positives = 61/118 (51%), Gaps = 1/118 (0%) Frame = +2 Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316 +R E + + + SLD + V DA+ + E GE ++ QG G++F++I G+ Sbjct: 264 KRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGEKIVVQGAPGNDFFIITEGIAS 323 Query: 317 VLVTGDDRVEKV-VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 VL D E V V S FGE+AL+ N PRAA+V A+ +DR F R+L Sbjct: 324 VLQRRSDNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRIRFERVL 381 >UniRef50_UPI0000D562F1 Cluster: PREDICTED: similar to CG3324-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG3324-PA - Tribolium castaneum Length = 636 Score = 86.6 bits (205), Expect = 3e-16 Identities = 39/109 (35%), Positives = 68/109 (62%) Frame = +2 Query: 188 LDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYE 367 L +++Q V+D M+ + P + +I++GDDG + YV G ++V+ G KVV T+ Sbjct: 70 LQNKKLQDVVDCMYPESVSPSQTIIKEGDDGSHLYVSVTGTYEVIQNG-----KVVKTFS 124 Query: 368 GSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 FGELAL+YN R A+++A+T G +W +DR F+ +++ S ++R+ Sbjct: 125 DVRVFGELALLYNAKRIATIKARTFGKVWILDRVVFKHLMVNSDIEQRQ 173 Score = 40.3 bits (90), Expect = 0.025 Identities = 27/104 (25%), Positives = 52/104 (50%), Gaps = 1/104 (0%) Frame = +2 Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGD-DGDNFYVIENGVF 313 QR + + ++ + S+ + +++V + G ++ +G+ + D FY+I+ G Sbjct: 171 QRQEIVDFLKQVPKLNSVPLEVLEEVASLLKLDFFPTGTKIVEEGEVNPDKFYIIKAGSV 230 Query: 314 DVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAG 445 V + ++K+ Y+GS FGELAL+ R A+V A G Sbjct: 231 TVSKKNEGAIDKL---YKGS-FFGELALLKEKERKATVMADPPG 270 >UniRef50_Q8MQE4 Cluster: Putative uncharacterized protein; n=5; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 617 Score = 84.6 bits (200), Expect = 1e-15 Identities = 50/131 (38%), Positives = 75/131 (57%) Frame = +2 Query: 116 VFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYV 295 + KSDA + A+R R+LDA Q++++ AM+ G +IRQGD G YV Sbjct: 52 IIGKSDAAFETIGNALRLNSFLRNLDATQIEKISSAMYPVEVPAGAIIIRQGDLGSIMYV 111 Query: 296 IENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTF 475 I+ G V V D+R V T E FGELA++++ R A+VRA + LWA++R+ F Sbjct: 112 IQEG--KVQVVKDNRF---VRTMEDGALFGELAILHHCERTATVRAIESCHLWAIERNVF 166 Query: 476 RRILLKSAFKK 508 I+++SA +K Sbjct: 167 HAIMMESAREK 177 >UniRef50_Q3SEP0 Cluster: CGMP-dependent protein kinase 8-2; n=8; Paramecium tetraurelia|Rep: CGMP-dependent protein kinase 8-2 - Paramecium tetraurelia Length = 795 Score = 83.8 bits (198), Expect = 2e-15 Identities = 45/124 (36%), Positives = 72/124 (58%) Frame = +2 Query: 110 PAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNF 289 P + P++ + + + +F S++ Q+ Q+ +MF R G+ +I+QGD +F Sbjct: 76 PLMKPQTPQDIGFIVKCFQSHFVFSSMNETQLVQLAKSMFYCRLVIGQTIIKQGDGASSF 135 Query: 290 YVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRH 469 +V+E G +VLV G R + +G+G FGELAL+YN PR+A+ A LW +DRH Sbjct: 136 FVLEKGKINVLVDGISRKQLT----QGNG-FGELALLYNAPRSATCVAMEECFLWGIDRH 190 Query: 470 TFRR 481 TFR+ Sbjct: 191 TFRK 194 Score = 35.5 bits (78), Expect = 0.72 Identities = 21/101 (20%), Positives = 45/101 (44%), Gaps = 1/101 (0%) Frame = +2 Query: 134 AQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVF 313 +++ + + + + F L Q + + ++ E ++ +GD +FY+I G Sbjct: 202 SEQEKNRQLLEQVKFFNQLTKDQKDAIAGVLILQKFNQNEIIVNEGDQASSFYIIVEGKC 261 Query: 314 DVLVTGDDRVEKVVHTYEGSGSFGELALMY-NMPRAASVRA 433 V ++ + + T SFGE AL + N R +++A Sbjct: 262 GVF----NKEDVQIATLNPKDSFGESALKHDNQIRMMTIKA 298 >UniRef50_A0E3G7 Cluster: Chromosome undetermined scaffold_76, whole genome shotgun sequence; n=5; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_76, whole genome shotgun sequence - Paramecium tetraurelia Length = 864 Score = 81.4 bits (192), Expect = 1e-14 Identities = 37/104 (35%), Positives = 66/104 (63%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355 +F+S+ ++ V+D MF G++V +QGD ++++IE G +++ G+ + Sbjct: 117 IFKSVPQSDIEYVVDQMFYCTVPDGQFVFKQGDMASSYFLIERGQCQIIINGE-----LK 171 Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 T + +FGELA++YN PR+ASV+A A WA+DR+TFR+++ Sbjct: 172 KTLKSGDAFGELAMLYNAPRSASVKAIGDCAFWAIDRNTFRKVV 215 Score = 45.6 bits (103), Expect = 7e-04 Identities = 26/93 (27%), Positives = 47/93 (50%) Frame = +2 Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334 E ++ + F L +Q + + + GE ++ +GD ++FY+I+ G ++ GD Sbjct: 228 EFMKKVEFFSFLTEEQRDAISSVLITSVFKKGEIIVSEGDVANSFYIIKKGKV-AIIKGD 286 Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 433 V ++ SFGE AL + RAA+V+A Sbjct: 287 KEVSQM----NAGESFGEAALYQSCQRAATVKA 315 >UniRef50_Q13237 Cluster: cGMP-dependent protein kinase 2; n=23; Euteleostomi|Rep: cGMP-dependent protein kinase 2 - Homo sapiens (Human) Length = 762 Score = 81.0 bits (191), Expect = 1e-14 Identities = 42/143 (29%), Positives = 79/143 (55%) Frame = +2 Query: 71 TYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPG 250 TYD + A K +++ + +A+ + LD QQ++ +++ M+ + + G Sbjct: 133 TYDLNKPPEFSFEKARVRKDSSEKKLITDALNKNQFLKRLDPQQIKDMVECMYGRNYQQG 192 Query: 251 EYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVR 430 Y+I+QG+ G++ +V+ G +V + EK++ + +FGELA++YN R ASV+ Sbjct: 193 SYIIKQGEPGNHIFVLAEGRLEVF-----QGEKLLSSIPMWTTFGELAILYNCTRTASVK 247 Query: 431 AQTAGALWAMDRHTFRRILLKSA 499 A T WA+DR F+ I+ ++A Sbjct: 248 AITNVKTWALDREVFQNIMRRTA 270 Score = 53.6 bits (123), Expect = 3e-06 Identities = 29/110 (26%), Positives = 62/110 (56%), Gaps = 3/110 (2%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL--VTGD 334 +R + L ++L ++ +++D + + + G+Y+IR+G++G F+++ G V G Sbjct: 281 LRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGH 340 Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAG-ALWAMDRHTFRR 481 D+ +++ T + FGE AL+ + R+A++ A+ A +DR TF + Sbjct: 341 DQ-PQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETFNQ 389 >UniRef50_Q03042 Cluster: cGMP-dependent protein kinase, isozyme 1; n=28; Eumetazoa|Rep: cGMP-dependent protein kinase, isozyme 1 - Drosophila melanogaster (Fruit fly) Length = 768 Score = 80.6 bits (190), Expect = 2e-14 Identities = 40/131 (30%), Positives = 76/131 (58%), Gaps = 1/131 (0%) Frame = +2 Query: 119 FPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVI 298 + K + + ++ +A+ +++DA Q+++++D+M+ K GE+VIR+G+ G + YV Sbjct: 166 YEKDFSDKQQIKDAIMDNDFLKNIDASQVRELVDSMYSKSIAAGEFVIREGEVGAHLYVS 225 Query: 299 ENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA-QTAGALWAMDRHTF 475 G F V+ G KV+ +FGELA++YN R AS+R A +W +DR F Sbjct: 226 AAGEFAVMQQG-----KVLDKMGAGKAFGELAILYNCTRTASIRVLSEAARVWVLDRRVF 280 Query: 476 RRILLKSAFKK 508 ++I++ + ++ Sbjct: 281 QQIMMCTGLQR 291 Score = 50.4 bits (115), Expect = 2e-05 Identities = 32/112 (28%), Positives = 56/112 (50%), Gaps = 3/112 (2%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL--VTGD 334 +R + L +L + + ++ D + + G Y+IRQG GD+F++I G V +T Sbjct: 299 LRSVPLLMNLSEELLAKIADVLELEFYAAGTYIIRQGTAGDSFFLISQGNVRVTQKLTPT 358 Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGA-LWAMDRHTFRRIL 487 E + T FGE AL+ R A++ A + G +DR +F+R++ Sbjct: 359 SPEETELRTLSRGDYFGEQALINEDKRTANIIALSPGVECLTLDRDSFKRLI 410 >UniRef50_Q16JU3 Cluster: Cgmp-dependent protein kinase; n=2; Endopterygota|Rep: Cgmp-dependent protein kinase - Aedes aegypti (Yellowfever mosquito) Length = 966 Score = 77.8 bits (183), Expect = 1e-13 Identities = 36/109 (33%), Positives = 65/109 (59%) Frame = +2 Query: 188 LDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYE 367 +D ++++ V DAM P Y+I++GD G +F+V +G ++V+ KV+ ++ Sbjct: 404 MDEERLKAVTDAMSPMTFPPNSYIIKEGDIGAHFFVSADGTYEVVAEN-----KVIKSFG 458 Query: 368 GSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 FGELA++Y R AS+R T +W ++R F++I++KS K+R+ Sbjct: 459 RGVVFGELAILYKAKRFASIRVTTEAKVWMLERKVFQKIMMKSGRKERE 507 Score = 60.5 bits (140), Expect = 2e-08 Identities = 32/107 (29%), Positives = 55/107 (51%), Gaps = 1/107 (0%) Frame = +2 Query: 170 ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEK 349 + + + L +++ ++ D + + G +I+QGD GD FY+I G +V+ T V+K Sbjct: 516 VSILKDLQTEKLHKISDLLKREFYATGSTIIQQGDPGDKFYIIRGGSVNVIKTDRHGVDK 575 Query: 350 VVHTYEGSGSFGELALMYNMPRAASVRAQTAGA-LWAMDRHTFRRIL 487 +V T + FGE AL++ R AS+ A G ++R F L Sbjct: 576 LVGTLQRGAYFGEQALLHEDRRLASIIANPPGTECLTLNRIAFNEFL 622 >UniRef50_UPI0000DB6E55 Cluster: PREDICTED: similar to cGMP-dependent protein kinase 21D CG3324-PA; n=2; Apocrita|Rep: PREDICTED: similar to cGMP-dependent protein kinase 21D CG3324-PA - Apis mellifera Length = 723 Score = 77.4 bits (182), Expect = 2e-13 Identities = 40/132 (30%), Positives = 72/132 (54%), Gaps = 1/132 (0%) Frame = +2 Query: 107 APA-VFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGD 283 AP+ V+ K + R ++ +A+ +L+ Q++ ++ AM+ K+ P VI++GD G Sbjct: 123 APSPVYEKDEKSRQQIRKAILENEFLGNLEENQVEALVSAMYSKQIPPNTLVIQEGDIGS 182 Query: 284 NFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMD 463 + YV G FD+ + T+ +FGE+AL+YN R S++ + G +W +D Sbjct: 183 HLYVSAEGEFDIYEGNTFQ-----RTFGPGVAFGEIALLYNTMRLRSIKVKKGGKVWVLD 237 Query: 464 RHTFRRILLKSA 499 R F +++KSA Sbjct: 238 RSVFLTVMMKSA 249 Score = 34.7 bits (76), Expect = 1.3 Identities = 15/47 (31%), Positives = 26/47 (55%) Frame = +2 Query: 257 VIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELAL 397 ++RQG+ G+ FY+I G + +D +E+ + FGELA+ Sbjct: 295 IVRQGEKGEKFYIISGGNVKITKDTEDGMEEELVVLGKGQYFGELAI 341 >UniRef50_Q22SE3 Cluster: Cyclic nucleotide-binding domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 451 Score = 76.2 bits (179), Expect = 4e-13 Identities = 39/121 (32%), Positives = 75/121 (61%) Frame = +2 Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 304 KS + + + +++ +F +L ++++ V MF + EYV +Q D ++++IE+ Sbjct: 99 KSKSDQDLIMNSLKNHYVFYALTDEELEFVTQKMFYCENT-AEYVFKQEDKASSYFIIES 157 Query: 305 GVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484 G D+++ +D V++ ++ E SFGELAL+YN PR+AS+R + WA+DR++FR+ Sbjct: 158 GQVDIII--NDEVKRTLNPGE---SFGELALLYNAPRSASIRCKGNCHFWAIDRNSFRKT 212 Query: 485 L 487 + Sbjct: 213 I 213 Score = 54.8 bits (126), Expect = 1e-06 Identities = 31/103 (30%), Positives = 54/103 (52%) Frame = +2 Query: 179 FRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVH 358 F+S++++Q + A+ + GE ++ +GD D+F++I+ G V + +K + Sbjct: 234 FKSMNSEQKDSIASALINIKFMKGENIVNEGDAADSFFMIKEGTVSVW-----KDKKEIR 288 Query: 359 TYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 SFGE AL + RAASVRA+ L ++ R +IL Sbjct: 289 KLGKGDSFGEQALYVSSKRAASVRAEGPVKLLSLGRDNLTKIL 331 >UniRef50_UPI0000519F68 Cluster: PREDICTED: similar to cGMP-dependent protein kinase 21D CG3324-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to cGMP-dependent protein kinase 21D CG3324-PA - Apis mellifera Length = 639 Score = 75.8 bits (178), Expect = 6e-13 Identities = 46/153 (30%), Positives = 77/153 (50%), Gaps = 1/153 (0%) Frame = +2 Query: 41 NNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLD 220 N R+ SV E + S + VF K + + + A+ ++ + +++ ++ Sbjct: 30 NERKHSVIGEV-----NVSSDMPIKVFEKDEKTKNLIKNAILNNEFLKNFNESRIETLIS 84 Query: 221 AMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSG-SFGELAL 397 AM+ ++ + +I +G+ G + YV E G F + V + + GSG +FGELAL Sbjct: 85 AMYPRKVKANTRIIHEGETGSHLYVSEEGTFKIYVNN------IYNENFGSGVAFGELAL 138 Query: 398 MYNMPRAASVRAQTAGALWAMDRHTFRRILLKS 496 +YN R S+ A T LW MDR F+ I+LKS Sbjct: 139 LYNTKRLCSIDACTDAKLWVMDRQIFQTIMLKS 171 Score = 44.4 bits (100), Expect = 0.002 Identities = 23/82 (28%), Positives = 40/82 (48%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340 VR I +F+ + + ++ D + + Y+IR+GD G+ FY+I+ G + + Sbjct: 183 VRQIEIFKDFSDEVLLKICDLIIVEFYPANSYIIREGDQGNKFYIIQGGHVKITKNKPND 242 Query: 341 VEKVVHTYEGSGSFGELALMYN 406 E+ + E FGE AL N Sbjct: 243 KEEELMILEKGDYFGEKALYDN 264 >UniRef50_Q22RR1 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 1219 Score = 75.8 bits (178), Expect = 6e-13 Identities = 41/119 (34%), Positives = 68/119 (57%), Gaps = 3/119 (2%) Frame = +2 Query: 140 RARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDV 319 + ++ A+R +F +L+ Q M QV++ MF + GE++ Q D+ F+ IE G ++ Sbjct: 437 KQKIKAAIRRHFIFSNLEEQHMNQVVNKMFACTCKQGEFIFEQNDEASLFFFIEQGNVNI 496 Query: 320 LVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGA---LWAMDRHTFRRIL 487 + + +K + + SFGELAL+YN PR+AS +A G LWA+DR TF ++ Sbjct: 497 KI--NKEFKKCLDEFT---SFGELALLYNSPRSASAQAAQDGVQLILWAIDRVTFLNVI 550 Score = 36.7 bits (81), Expect = 0.31 Identities = 26/111 (23%), Positives = 53/111 (47%), Gaps = 2/111 (1%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340 + + F + +Q + ++ GE ++ GDD ++FY+I++G V + ++ Sbjct: 565 LENVSFFSNFTHEQKDLLASQFTYQKFHKGETIVNIGDDANSFYIIKSG--QVSIISQNQ 622 Query: 341 VEKVVHTYEGSGSFGELALMYNMP-RAASVRAQTAGA-LWAMDRHTFRRIL 487 +E+ + FGE +L N R +V+A++ L A+ R + IL Sbjct: 623 IEE--RQLQSGDWFGESSLYLNKSIRTRTVQAKSFDVILLALSRKATQEIL 671 >UniRef50_Q9FXQ0 Cluster: Cyclic nucreotide dependent protein kinase II; n=2; Chlamydomonas reinhardtii|Rep: Cyclic nucreotide dependent protein kinase II - Chlamydomonas reinhardtii Length = 718 Score = 75.4 bits (177), Expect = 7e-13 Identities = 40/115 (34%), Positives = 67/115 (58%), Gaps = 3/115 (2%) Frame = +2 Query: 143 ARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDG---DNFYVIENGVF 313 A + A+ +LLF LD+Q ++++ M+E+ G+ +I++GD G YV+++G F Sbjct: 46 AFIENALGRLLLFGKLDSQVQRKIVSEMYERTVPAGDILIKEGDTGLAACELYVVKSGKF 105 Query: 314 DVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFR 478 +VL + +V + E FGE++LMY+ PR A+V A +WA+DR FR Sbjct: 106 EVLQKRQGQNVRV-NIKERGDCFGEISLMYDSPRTATVAATMDAVVWALDRQVFR 159 Score = 56.8 bits (131), Expect = 3e-07 Identities = 34/119 (28%), Positives = 61/119 (51%) Frame = +2 Query: 131 DAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGV 310 + Q +++ + + + +L ++ +++DA E + G+ VI +GD GD FY+++ G Sbjct: 167 ETQVSQVELFLNSVPILANLSREERIRLVDAFEENTYQAGQKVIVEGDKGDLFYIVKEGE 226 Query: 311 FDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 V KV H ++ + F E AL+ + PR A+V A T + R TF+ IL Sbjct: 227 AIVYQNTPGGQRKVNHLFK-ADFFSERALLKDEPRMATVEAYTKLVCLTLKRETFQEIL 284 >UniRef50_Q234E6 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 829 Score = 75.4 bits (177), Expect = 7e-13 Identities = 40/109 (36%), Positives = 65/109 (59%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340 +R +F +L Q++ +++ MF + GE +I++ D+ F+++E G V V D Sbjct: 97 LRNHFVFYNLQDSQLETLVNEMFYCELQEGETIIKEEDNASTFFILEQGRIQVSVK--DN 154 Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 V++ + EG FGELAL+YN PR+AS +A LW +DR TFRR++ Sbjct: 155 VKRDIVPGEG---FGELALLYNAPRSASCKALQKCHLWGIDRATFRRVV 200 >UniRef50_A2EKL9 Cluster: Cyclic nucleotide-binding domain containing protein; n=2; Trichomonas vaginalis G3|Rep: Cyclic nucleotide-binding domain containing protein - Trichomonas vaginalis G3 Length = 374 Score = 75.4 bits (177), Expect = 7e-13 Identities = 43/132 (32%), Positives = 73/132 (55%), Gaps = 1/132 (0%) Frame = +2 Query: 122 PKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIE 301 PK+ + ++ + + L + Q+ +++A F+ + + +I+QGD DNFY+I+ Sbjct: 117 PKTPEEYTQIETICKKVSFLSYLKSDQLDALINAFFKMEFKDKDVIIKQGDKPDNFYIIQ 176 Query: 302 NGVFDV-LVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFR 478 +G D+ TGD KV+ EGS FGELALM RAA+V A WA+D+ T+ Sbjct: 177 SGNVDIWKKTGDAPEVKVITLSEGS-YFGELALMSGRTRAATVIAAGTVYCWAIDQTTYL 235 Query: 479 RILLKSAFKKRK 514 +L +++R+ Sbjct: 236 YLLKDIHYQRRQ 247 Score = 57.6 bits (133), Expect = 2e-07 Identities = 37/119 (31%), Positives = 59/119 (49%) Frame = +2 Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316 +R + E + + +F L Q V +A + +P +I+QG+ G+ FYVI G D Sbjct: 245 RRQKCKEIISEVPIFNQLPDYQAILVAEAAVLEEYQPATTIIKQGEIGNKFYVILAGTVD 304 Query: 317 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLK 493 V++ G K V+ FGE AL+YN RAA++ + + + FR+IL K Sbjct: 305 VIIDG-----KKVNELGPGKYFGERALIYNCARAATIITTSQVRIAYISGEVFRKILDK 358 >UniRef50_A0D9C4 Cluster: Chromosome undetermined scaffold_42, whole genome shotgun sequence; n=8; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_42, whole genome shotgun sequence - Paramecium tetraurelia Length = 825 Score = 74.5 bits (175), Expect = 1e-12 Identities = 33/120 (27%), Positives = 69/120 (57%) Frame = +2 Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 328 + ++ +G +F SL Q+ ++++ MF + +++ +QGD +++VIE G ++++ Sbjct: 117 IRKSFKGHFVFFSLPEDQIAKLIEHMFYCTLKANQFIFKQGDQASSYFVIEKGSVEIIIN 176 Query: 329 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKK 508 ++ + T FGE+AL+YN R+AS+R T W++DR TF++ + + K+ Sbjct: 177 -----DRQIRTLAEGSYFGEIALLYNATRSASIRTLTDCGFWSLDRSTFKKTIEELMLKE 231 Score = 52.0 bits (119), Expect = 8e-06 Identities = 31/103 (30%), Positives = 50/103 (48%) Frame = +2 Query: 179 FRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVH 358 F + ++Q + A+ + PG+ ++ +GD D+FYVI++G VL G + K+ Sbjct: 245 FSFMTSEQKDSIAHALITTKFAPGQAIVNEGDQADSFYVIKSGEVSVL-KGTKEIRKM-- 301 Query: 359 TYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 SFGE AL R A+ A+T A+ R +IL Sbjct: 302 --GAKDSFGEQALYEKSKRGATCVAETEVKCVALGRENLTKIL 342 >UniRef50_A0DCJ0 Cluster: Chromosome undetermined scaffold_45, whole genome shotgun sequence; n=7; Oligohymenophorea|Rep: Chromosome undetermined scaffold_45, whole genome shotgun sequence - Paramecium tetraurelia Length = 775 Score = 73.3 bits (172), Expect = 3e-12 Identities = 35/102 (34%), Positives = 64/102 (62%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355 +F +L +++ +++ MF + G Y+ +Q D F++++ G +V+V +++ ++ + Sbjct: 73 VFYNLSEAELENIVNKMFYCEAAAGAYIFKQQDHATCFFILQRGSLEVIV--NEKAKREL 130 Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481 T +G FGELAL+YN PR+ASV+ LW +DR+TFRR Sbjct: 131 KTGDG---FGELALLYNAPRSASVKCFENCNLWGIDRNTFRR 169 Score = 56.4 bits (130), Expect = 4e-07 Identities = 37/121 (30%), Positives = 60/121 (49%) Frame = +2 Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 304 K + + E VR F +L +Q + + ++ + ++ +GD G +FY+I+ Sbjct: 177 KEYEENRKFMEVVR---FFHNLTNEQKDAIAAVLIVQKFYKNQIIVNEGDPGSSFYIIKE 233 Query: 305 GVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484 G VL G+ V K+ Y+G SFGE AL YN R +VRA+ A+ R + +I Sbjct: 234 GTVSVL-KGNKEVRKL---YKGD-SFGEQALYYNTVRQMTVRAEDDVKCLALGRDSLTKI 288 Query: 485 L 487 L Sbjct: 289 L 289 >UniRef50_Q6P5T7 Cluster: PRKG1 protein; n=14; Euteleostomi|Rep: PRKG1 protein - Homo sapiens (Human) Length = 312 Score = 73.3 bits (172), Expect = 3e-12 Identities = 45/155 (29%), Positives = 78/155 (50%), Gaps = 1/155 (0%) Frame = +2 Query: 47 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226 +R+++ AE + D +PKS + + EA+ ++L+ Q+Q+++D M Sbjct: 75 KRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCM 134 Query: 227 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMY 403 + +I++GD G YV+E+G +V G V G G FGELA++Y Sbjct: 135 YPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILY 188 Query: 404 NMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKK 508 N R A+V+ LWA+DR F+ I++++ K Sbjct: 189 NCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIK 223 Score = 50.0 bits (114), Expect = 3e-05 Identities = 28/82 (34%), Positives = 42/82 (51%), Gaps = 1/82 (1%) Frame = +2 Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334 E ++ + F+SL + + ++ D + E E GEY+IRQG GD F++I G +V Sbjct: 229 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 288 Query: 335 DRVEKVVHTYEGSGS-FGELAL 397 + V G G FGE AL Sbjct: 289 PSEDPVFLRTLGKGDWFGEKAL 310 >UniRef50_P14619 Cluster: cGMP-dependent protein kinase 1, beta isozyme; n=49; Bilateria|Rep: cGMP-dependent protein kinase 1, beta isozyme - Homo sapiens (Human) Length = 686 Score = 73.3 bits (172), Expect = 3e-12 Identities = 45/155 (29%), Positives = 78/155 (50%), Gaps = 1/155 (0%) Frame = +2 Query: 47 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226 +R+++ AE + D +PKS + + EA+ ++L+ Q+Q+++D M Sbjct: 75 KRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCM 134 Query: 227 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMY 403 + +I++GD G YV+E+G +V G V G G FGELA++Y Sbjct: 135 YPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILY 188 Query: 404 NMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKK 508 N R A+V+ LWA+DR F+ I++++ K Sbjct: 189 NCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIK 223 Score = 60.9 bits (141), Expect = 2e-08 Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 1/112 (0%) Frame = +2 Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334 E ++ + F+SL + + ++ D + E E GEY+IRQG GD F++I G +V Sbjct: 229 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 288 Query: 335 DRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 + V G G FGE AL R A+V A A +DR +F+ ++ Sbjct: 289 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLI 340 >UniRef50_Q31QH3 Cluster: Cyclic nucleotide-binding; n=2; Synechococcus elongatus|Rep: Cyclic nucleotide-binding - Synechococcus sp. (strain PCC 7942) (Anacystis nidulans R2) Length = 449 Score = 72.9 bits (171), Expect = 4e-12 Identities = 40/113 (35%), Positives = 64/113 (56%) Frame = +2 Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 328 L +R + LFR D Q++ +++ + G+ + R+G+ G+ FY+I NG F V V Sbjct: 291 LPSLLRRVDLFRDYDDSQIRWLIEKGRRRTCVVGDVLCREGELGEEFYLILNGRFSVQVK 350 Query: 329 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 G E+ + T E FGELA+M ++PR A+V A G L+ +DR+ R +L Sbjct: 351 GR---EEAIATLESGNFFGELAVMLDIPRTATVVALEPGTLFVVDRNNLRHLL 400 >UniRef50_Q5RGL5 Cluster: Novel protein similar to vertebrate protein kinase, cGMP-dependent, type I; n=3; Danio rerio|Rep: Novel protein similar to vertebrate protein kinase, cGMP-dependent, type I - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 570 Score = 72.5 bits (170), Expect = 5e-12 Identities = 38/126 (30%), Positives = 67/126 (53%) Frame = +2 Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316 + +++ +A+ R LD +Q+ ++D M G+ +I++G +GD+ Y++ G Sbjct: 1 ETSQIVKAIGKNDFLRRLDEEQISMMVDLMKVLDCRAGDEIIKEGTEGDSMYIVAAGELK 60 Query: 317 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKS 496 V G D + FGELA++YN R ASV+A +A LW ++R T+R I+ Sbjct: 61 VTQAGRD-----LRILSPGDMFGELAILYNCKRTASVKAISAVKLWCIERQTYRSIMTNK 115 Query: 497 AFKKRK 514 + KR+ Sbjct: 116 SKMKRE 121 Score = 54.8 bits (126), Expect = 1e-06 Identities = 34/115 (29%), Positives = 63/115 (54%), Gaps = 1/115 (0%) Frame = +2 Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 304 KS +R +L ++ ++L+ Q+ +++D+M E R + E ++R+G +G+ FY+I Sbjct: 115 KSKMKREQLMGFLKTARTLKALNDVQLSKIIDSMEEVRFQDNEVIVREGAEGNTFYIILK 174 Query: 305 GVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDR 466 G +VLVT ++ G G FGELAL+ + R A+ A +++D+ Sbjct: 175 G--EVLVTKKVNGQQKTIRKMGEGEHFGELALIREILRTATCTAVGVVICFSIDK 227 >UniRef50_Q8MMZ4 Cluster: CGMP-dependent protein kinase; n=14; Apicomplexa|Rep: CGMP-dependent protein kinase - Plasmodium falciparum Length = 853 Score = 71.7 bits (168), Expect = 9e-12 Identities = 45/148 (30%), Positives = 76/148 (51%) Frame = +2 Query: 44 NRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDA 223 N++K++F+ ED E + K + +++ L+ +L+ ++ + + Sbjct: 14 NKKKAIFSNDDFTGEDSLMEDHLELREKLSEDIDMIKTSLKNNLVCSTLNDNEILTLSNY 73 Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403 M + G VI+QG+ G F++I +G FDV V +K V T SFGE AL++ Sbjct: 74 MQFFVFKSGNLVIKQGEKGSYFFIINSGKFDVYVN-----DKKVKTMGKGSSFGEAALIH 128 Query: 404 NMPRAASVRAQTAGALWAMDRHTFRRIL 487 N R+A++ A+T G LW + R TFR L Sbjct: 129 NTQRSATIIAETDGTLWGVQRSTFRATL 156 Score = 64.9 bits (151), Expect = 1e-09 Identities = 34/110 (30%), Positives = 64/110 (58%), Gaps = 1/110 (0%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340 ++ + +FR L +Q +++A R E G+Y+I++G+ G FY+I+NG +++ + Sbjct: 413 IKKMYIFRYLTDKQCNLLIEAFRTTRYEEGDYIIQEGEVGSRFYIIKNGEVEIV-----K 467 Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGA-LWAMDRHTFRRIL 487 +K + T + FGE AL+Y+ PR ASV ++ W +D+ F +I+ Sbjct: 468 NKKRLRTLGKNDYFGERALLYDEPRTASVISKVNNVECWFVDKSVFLQII 517 Score = 50.4 bits (115), Expect = 2e-05 Identities = 28/109 (25%), Positives = 54/109 (49%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340 + + +F L Q + +A + + GE +++QGD GD Y+++ G V + ++ Sbjct: 171 IDSVSVFDMLTEAQKNMITNACVIQNFKSGETIVKQGDYGDVLYILKEGKATVYINDEE- 229 Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 + E FGE AL+Y+ PR+A++ A+ A ++ R +L Sbjct: 230 ----IRVLEKGSYFGERALLYDEPRSATIIAKEPTACASICRKLLNIVL 274 >UniRef50_Q5CWD4 Cluster: Cyclic nucleotide (CGMP)-dependent protein kinase with 3 cNMP binding domains and a Ser/Thr kinase domain; n=3; Cryptosporidium|Rep: Cyclic nucleotide (CGMP)-dependent protein kinase with 3 cNMP binding domains and a Ser/Thr kinase domain - Cryptosporidium parvum Iowa II Length = 965 Score = 71.7 bits (168), Expect = 9e-12 Identities = 41/121 (33%), Positives = 66/121 (54%) Frame = +2 Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 304 K++ +++A+ G ++ SL+ ++ ++ +M E GE VI QG G F+VI Sbjct: 92 KTEEDIKTISKALAGNVVGASLNESEIATLVSSMHYYEYEVGEVVIEQGASGFYFFVIST 151 Query: 305 GVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484 G F V + G+ V+T +FGELAL++N PR+A++ G LW + R TFR Sbjct: 152 GSFGVEINGNR-----VNTMSEGTAFGELALIHNTPRSATILVIEKGGLWGLGRSTFRDT 206 Query: 485 L 487 L Sbjct: 207 L 207 Score = 54.8 bits (126), Expect = 1e-06 Identities = 31/115 (26%), Positives = 61/115 (53%), Gaps = 1/115 (0%) Frame = +2 Query: 146 RLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV 325 R +A++ +F+ + QQ+ ++ ++ + GE ++ QGD G F+++++G V Sbjct: 489 RKRDAIKSCFVFQYVSEQQLSLLVKSLRLVKFTSGEKIVVQGDKGTAFFILQSGEVAVY- 547 Query: 326 TGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGA-LWAMDRHTFRRIL 487 R K + + FGE AL+Y+ R+A++ A T LW +D+ F +I+ Sbjct: 548 ----RNNKFIRYLGKNDYFGERALLYDELRSATIEAATPEVHLWTVDKEAFLKIV 598 Score = 44.8 bits (101), Expect = 0.001 Identities = 26/109 (23%), Positives = 55/109 (50%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340 + + +F L +Q + +A+ + + +IR+ + G+ Y+I++G+ V V Sbjct: 222 IESLSIFSGLTDKQKSLLSEALVREIFVKDQVIIREKEIGNVLYMIKSGIVGVFVE---- 277 Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 +K + + +FGE +LM++ PR+A+V A ++R +IL Sbjct: 278 -DKYIRSLNEGDAFGERSLMFDEPRSATVIANATTECLTLNRGILTQIL 325 >UniRef50_A7PEK0 Cluster: Chromosome chr11 scaffold_13, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr11 scaffold_13, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 1049 Score = 70.5 bits (165), Expect = 2e-11 Identities = 39/75 (52%), Positives = 49/75 (65%), Gaps = 5/75 (6%) Frame = +2 Query: 281 DNFYVIENGVFDVLVTGDDR---VEKVVHTY--EGSGSFGELALMYNMPRAASVRAQTAG 445 D FYV+ +G F+VL T +++ V +V+ Y E SFGELALMYN P ASVRA T G Sbjct: 495 DCFYVVGSGEFEVLATQEEKNGEVTRVLQQYTAEKLSSFGELALMYNKPLQASVRAVTNG 554 Query: 446 ALWAMDRHTFRRILL 490 LWA+ R FR IL+ Sbjct: 555 TLWALKREDFRGILM 569 >UniRef50_Q9VL34 Cluster: CG4839-PA, isoform A; n=2; Sophophora|Rep: CG4839-PA, isoform A - Drosophila melanogaster (Fruit fly) Length = 1003 Score = 69.3 bits (162), Expect = 5e-11 Identities = 40/131 (30%), Positives = 69/131 (52%), Gaps = 1/131 (0%) Frame = +2 Query: 125 KSDAQRARLAEAV-RGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIE 301 K + R + A+ R L +D ++ + V++AM +IR+ ++G YV Sbjct: 414 KDEGTRNLIRTAIERNDFLNNLMDKERKEMVINAMAPASYRKHSLIIREHEEGSEIYVSA 473 Query: 302 NGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481 G +DV+ G ++V ++ + FGELA++YN PR AS+ A T +W + R TFR Sbjct: 474 EGQYDVIRGG-----QLVASFGPATVFGELAILYNAPRQASIEAATDARVWKIARETFRA 528 Query: 482 ILLKSAFKKRK 514 I+ S ++R+ Sbjct: 529 IMQISGSRERE 539 Score = 49.2 bits (112), Expect = 6e-05 Identities = 30/114 (26%), Positives = 53/114 (46%), Gaps = 1/114 (0%) Frame = +2 Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316 +R + +R + D + +V+D + K E ++R+G+ G+ FY+I G Sbjct: 537 EREENLQFLRSAPFLQEFDQSLLLKVVDLLQRKFYETDSCIVREGELGNEFYIIRCGTVT 596 Query: 317 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGA-LWAMDRHTF 475 + + + E++V + FGE AL+ R ASV A G + +DR F Sbjct: 597 IKKLDEQQQEQIVANRKRGDYFGEQALLNADVRQASVYADAPGTEVLMLDREAF 650 >UniRef50_O76360 Cluster: Egg laying defective protein 4, isoform a; n=5; Caenorhabditis elegans|Rep: Egg laying defective protein 4, isoform a - Caenorhabditis elegans Length = 780 Score = 68.9 bits (161), Expect = 6e-11 Identities = 39/146 (26%), Positives = 73/146 (50%) Frame = +2 Query: 47 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226 +R A + +P ++ + K+ + + +AV+ + L +Q+ ++++ M Sbjct: 158 QRAKKIAVSAEPTNFENKPATLQHYNKTVGAKQMIRDAVQKNDFLKQLAKEQIIELVNCM 217 Query: 227 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYN 406 +E R+ G++VI++G+ GD +V+ G V R ++ GELA++YN Sbjct: 218 YEMRARAGQWVIQEGEPGDRLFVVAEGELQV-----SREGALLGKMRAGTVMGELAILYN 272 Query: 407 MPRAASVRAQTAGALWAMDRHTFRRI 484 R ASV+A T LW +DR F+ I Sbjct: 273 CTRTASVQALTDVQLWVLDRSVFQMI 298 Score = 57.6 bits (133), Expect = 2e-07 Identities = 32/119 (26%), Positives = 62/119 (52%), Gaps = 2/119 (1%) Frame = +2 Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316 + ++L + + +F++L ++ ++ D M + + G Y+IRQG+ GD F+VI +G Sbjct: 306 RHSQLMNFLTKVSIFQNLSEDRISKMADVMDQDYYDGGHYIIRQGEKGDAFFVINSGQVK 365 Query: 317 VLVTGDDRVE-KVVHTYEGSGSFGELALMYNMPRAASVRAQTAGA-LWAMDRHTFRRIL 487 V + E + + FGE AL+ R A++ AQ G + +DR +F +++ Sbjct: 366 VTQQIEGETEPREIRVLNQGDFFGERALLGEEVRTANIIAQAPGVEVLTLDRESFGKLI 424 >UniRef50_O17474 Cluster: Cyclic GMP-dependent protein kinase; n=1; Hydra oligactis|Rep: Cyclic GMP-dependent protein kinase - Hydra oligactis (Hydra) Length = 742 Score = 68.9 bits (161), Expect = 6e-11 Identities = 48/162 (29%), Positives = 89/162 (54%) Frame = +2 Query: 29 VARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQ 208 V N+R +V AE+ E + D P + PKS + +++AV + L+ Q++ Sbjct: 115 VKTVRNKRFAVSAES-GKELQNLD--FPKI-PKSTEVKEFISQAVLKNNFLKHLEECQVK 170 Query: 209 QVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGE 388 +++ M +K + GEY+I++GD G+ +V G+ ++ GD + K + E FGE Sbjct: 171 EIVLFMSQKSFKRGEYIIKEGDMGNALFVSYVGLLEIS-QGDKILGKPLRPGE---LFGE 226 Query: 389 LALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 LA++YN R ASV+A +W ++R+ F+ ++ K+ +R+ Sbjct: 227 LAILYNCTRTASVKAIDDVEVWYLERNVFQAVMQKTGIMRRE 268 Score = 60.5 bits (140), Expect = 2e-08 Identities = 34/121 (28%), Positives = 66/121 (54%), Gaps = 3/121 (2%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL--VTGD 334 + + +F++L + ++++ + E+ E GE+++R+G+ GD+FY+++ G+ VL + G Sbjct: 274 LHSVPVFKNLPNDTLLKIVEVIEEEFYEDGEFIVREGERGDSFYILKQGLVKVLQMIEGK 333 Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGA-LWAMDRHTFRRILLKSAFKKR 511 D ++ H +G FGE AL+ R ASV A G ++R F + ++ K Sbjct: 334 DEPVEIRHLSQGE-YFGEKALLGEDVRTASVVASIGGVHCLVIERDVFMSFIGDLSYLKN 392 Query: 512 K 514 K Sbjct: 393 K 393 >UniRef50_A7C1J1 Cluster: Protein kinase, cGMP-dependent, type I; n=1; Beggiatoa sp. PS|Rep: Protein kinase, cGMP-dependent, type I - Beggiatoa sp. PS Length = 429 Score = 68.5 bits (160), Expect = 8e-11 Identities = 35/100 (35%), Positives = 59/100 (59%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355 LF + QQ+++++ ++ K+ +P E +IRQGDD Y+IE G+F V + D+R +VV Sbjct: 144 LFTYVPTQQLRRLVSSLKAKKLQPNEILIRQGDDAKEAYIIEKGLFTVQI--DERPNQVV 201 Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTF 475 T GE+AL+ N R +V AQT +++ + + F Sbjct: 202 RTMIPGDLVGEIALVKNTKRTTNVIAQTRASVFVLPQPEF 241 >UniRef50_Q4QGD8 Cluster: Protein kinase A regulatory subunit, putative; n=7; Trypanosomatidae|Rep: Protein kinase A regulatory subunit, putative - Leishmania major Length = 502 Score = 68.5 bits (160), Expect = 8e-11 Identities = 48/158 (30%), Positives = 80/158 (50%), Gaps = 2/158 (1%) Frame = +2 Query: 47 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226 RR++V E DPE + P V KS + + + +LF L ++ + V AM Sbjct: 203 RRQTVRVEGIDPEA--AKNYVPPVHEKSQEDTDMICKLLSHNVLFGFLGSKDILTVAGAM 260 Query: 227 FEKRSEPGEYVIRQGDDG-DNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403 + + E +I G D YVI++G DV+ G +KV EG+ + GEL L+Y Sbjct: 261 YREEFVKDERIIEFGQTHCDKLYVIQSGEADVIKEG----QKVFVKTEGT-AVGELELLY 315 Query: 404 NMPRAASVRAQTAGAL-WAMDRHTFRRILLKSAFKKRK 514 + P A+V+ T + W +DR T+R +++ S ++R+ Sbjct: 316 DTPAVATVKVSTEVLVAWVLDRETYRNLVMGSCIRRRE 353 Score = 41.1 bits (92), Expect = 0.015 Identities = 24/98 (24%), Positives = 42/98 (42%) Frame = +2 Query: 182 RSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHT 361 +SLDA + Q+ DA+ G+Y+I ++G+ Y+I G +V+ + V Sbjct: 366 QSLDAYERMQIADALTSDEFAAGDYIIHYDEEGEWLYIIIEGTVEVIGRDAAGNKTKVCE 425 Query: 362 YEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTF 475 + GEL + A + A T ++R F Sbjct: 426 FHSGDHIGELEFLNKHRTVADIVAVTGVTTAKLNRRHF 463 >UniRef50_Q23DN8 Cluster: Cyclic nucleotide-binding domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 808 Score = 68.1 bits (159), Expect = 1e-10 Identities = 35/96 (36%), Positives = 56/96 (58%) Frame = +2 Query: 194 AQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGS 373 AQ+++ + MF +++ +Q D+ +F+++E G +V+V EK + Sbjct: 92 AQRVELTIK-MFYCEVPMNDFIFKQSDNATSFFILERGAMEVIVN-----EKSKRELKAG 145 Query: 374 GSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481 FGELAL+YN PR+ASV+A LW +DR+TFRR Sbjct: 146 DGFGELALLYNAPRSASVKALDHCYLWGIDRNTFRR 181 Score = 51.2 bits (117), Expect = 1e-05 Identities = 35/121 (28%), Positives = 58/121 (47%) Frame = +2 Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 304 K + + E VR F +L +Q + + ++ + ++ +GD +FY+I+ Sbjct: 189 KEYEENRKFMEVVR---FFHNLTNEQKDAIAAVLIVQKFYKNQVIVTEGDPASSFYIIKE 245 Query: 305 GVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484 G V G+ V K+ Y+G SFGE AL YN R +VRA+ A+ R T ++ Sbjct: 246 GNVTVW-KGNKEVRKL---YKGD-SFGEQALYYNTVRQMTVRAEDEVKCLALGRDTLTKV 300 Query: 485 L 487 L Sbjct: 301 L 301 >UniRef50_Q4QF64 Cluster: Protein kinase, putative; n=2; Leishmania|Rep: Protein kinase, putative - Leishmania major Length = 2689 Score = 67.7 bits (158), Expect = 1e-10 Identities = 51/173 (29%), Positives = 82/173 (47%), Gaps = 9/173 (5%) Frame = +2 Query: 23 PPVARFNNRRKSVFAETYDPEEDDSDEGAPA-------VFPKSDAQRARLAEAVRGILLF 181 P + RR +V A P + E +PA V PKS A+ +L +R F Sbjct: 301 PTGGQCQGRRLAVSAAPCMPPPEIIGEDSPATALPPLRVVPKSPAEEQQLRRLLRRCHSF 360 Query: 182 RSLDAQQMQQVLDAMFEKRSEPGEYVIRQGD-DGDNFYVIENGVFDVLVTGDDRVEKVVH 358 SL+A ++ VL AM ++ G ++ QG + Y++ G + + G K + Sbjct: 361 SSLEADTLESVLKAMDKEVHAAGAAILEQGQATTEKLYLVGEGTCEAIKNG-----KSLG 415 Query: 359 TYEGSGSFGELALMYNMPR-AASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 + G+FGEL LMY AA+VR T L+ +D ++ R ++ SA +KR+ Sbjct: 416 PLQPGGTFGELELMYKQAMCAATVRCVTRCVLYTLDEASYHRAVMTSALQKRR 468 >UniRef50_A0BE58 Cluster: Chromosome undetermined scaffold_101, whole genome shotgun sequence; n=17; Oligohymenophorea|Rep: Chromosome undetermined scaffold_101, whole genome shotgun sequence - Paramecium tetraurelia Length = 823 Score = 66.9 bits (156), Expect = 3e-10 Identities = 33/91 (36%), Positives = 55/91 (60%) Frame = +2 Query: 206 QQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFG 385 + ++ MF R E+V +Q D +++I+ GV ++++ G+ V+K + T +G FG Sbjct: 135 EDIVMKMFYCRVAGNEFVFQQNDQASAYFIIDQGVCEIIINGE--VKKQLSTGDG---FG 189 Query: 386 ELALMYNMPRAASVRAQTAGALWAMDRHTFR 478 ELAL+Y PR+ASV+ + W +DR TFR Sbjct: 190 ELALLYGAPRSASVKTKDECFFWCIDRGTFR 220 Score = 44.4 bits (100), Expect = 0.002 Identities = 27/110 (24%), Positives = 52/110 (47%), Gaps = 1/110 (0%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340 + I F + Q + A+ ++ + G+ ++ +GD ++++I++G+ ++ G++ Sbjct: 238 IDSIKFFEWMTVDQKDMIAGAIIAQQFKKGQAIVNEGDMASSYFIIKSGMVKIMKGGNE- 296 Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAG-ALWAMDRHTFRRIL 487 + SFGE AL N R ASV A A+ R T +IL Sbjct: 297 ----LRQMSAGDSFGEQALYQNSVRGASVIAVDENVCCLAIGRETITKIL 342 >UniRef50_A4S6U9 Cluster: Predicted protein; n=2; Ostreococcus|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 680 Score = 66.1 bits (154), Expect = 4e-10 Identities = 38/111 (34%), Positives = 57/111 (51%) Frame = +2 Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 328 L EA+ F LDA ++V MF G ++ + + GD Y+I G FDVL Sbjct: 16 LCEALSQTFTFSELDANVRRRVASEMFFINVPEGTILMEEDEPGDALYLIAGGEFDVLQN 75 Query: 329 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481 V+ +G GELAL+Y++PR+A+VRA+T +W + F+R Sbjct: 76 RLGADISVLTRTKGD-IIGELALLYSVPRSATVRAKTRSQVWVCTQQVFKR 125 >UniRef50_Q01E02 Cluster: CGMP-dependent protein kinase, putative; n=2; Ostreococcus|Rep: CGMP-dependent protein kinase, putative - Ostreococcus tauri Length = 935 Score = 61.3 bits (142), Expect = 1e-08 Identities = 40/104 (38%), Positives = 55/104 (52%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355 LF +L QQ+ + +A + E + V RQGD G FY+IE G V V G +VV Sbjct: 248 LFNALSEQQLITISNAARRETYEARDEVFRQGDPGHCFYIIERGEVSVRVNG----AEVV 303 Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 G FGE AL+ N PRAA++ A T + ++R TF +L Sbjct: 304 KLSRGD-FFGERALVNNEPRAATIYAMTEVSCLVLNRQTFVSML 346 Score = 51.6 bits (118), Expect = 1e-05 Identities = 33/123 (26%), Positives = 58/123 (47%), Gaps = 5/123 (4%) Frame = +2 Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG---VFDVLV 325 E + + + L +++Q + + + + E VI+QG+ GD +++E+G V D Sbjct: 477 ETLSKVPILSKLSPEEIQNLAEELTDVSFRANETVIKQGESGDAMFILESGEVEVIDEKT 536 Query: 326 TGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL--LKSA 499 K++ S FGEL L+ + PRAA+VR + + R F + L LK Sbjct: 537 LNTSGDPKLLCKLGPSSYFGELGLLNSDPRAATVRVPNRATVLVITRRVFEQHLGSLKEI 596 Query: 500 FKK 508 K+ Sbjct: 597 LKR 599 Score = 45.6 bits (103), Expect(2) = 5e-10 Identities = 25/67 (37%), Positives = 36/67 (53%), Gaps = 1/67 (1%) Frame = +2 Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDG-DNFYVIE 301 ++ A + A+ G LLF LDA ++V DAM + VI QGDD + FY+IE Sbjct: 78 RTTASEQAIERAMEGNLLFAELDAASRRRVADAMMPMYVGENDVVIAQGDDECERFYIIE 137 Query: 302 NGVFDVL 322 +G V+ Sbjct: 138 SGEASVM 144 Score = 40.3 bits (90), Expect(2) = 5e-10 Identities = 24/64 (37%), Positives = 32/64 (50%) Frame = +2 Query: 323 VTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAF 502 V D V T FGELAL+Y PR+A++ AQT LW + F+ I K + Sbjct: 174 VVYDPATATCVATLGPGRGFGELALLYACPRSATIVAQTPMKLWTLHSSAFKAI--KHSV 231 Query: 503 KKRK 514 KR+ Sbjct: 232 AKRE 235 >UniRef50_Q8MMZ5 Cluster: CGMP-dependent protein kinase; n=2; Eimeria|Rep: CGMP-dependent protein kinase - Eimeria maxima Length = 1007 Score = 65.7 bits (153), Expect = 6e-10 Identities = 35/122 (28%), Positives = 69/122 (56%), Gaps = 1/122 (0%) Frame = +2 Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 304 K+D+ + + ++ G L+ SL+ +++ + +A+ G+ V +QG++G F+++ + Sbjct: 164 KTDSDLSLIRSSLSGNLVCSSLNDSEVEALANAVQFFTFAKGDIVTKQGENGSYFFIVHS 223 Query: 305 GVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA-QTAGALWAMDRHTFRR 481 G F+V+V EKVV+ +FGE++L++N R A+++ ALW + R FR Sbjct: 224 GEFEVIVN-----EKVVNKIVQGQAFGEISLIHNSARTATIKTLSDQAALWGVQRQVFRE 278 Query: 482 IL 487 L Sbjct: 279 TL 280 Score = 55.2 bits (127), Expect = 8e-07 Identities = 35/105 (33%), Positives = 56/105 (53%), Gaps = 1/105 (0%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355 +FR L QQ Q ++ A R GE +IR+G+ G F++I+ G +L G + V Sbjct: 574 IFRYLSEQQTQTLIRAFKTVRYTQGEAIIREGEIGSRFFIIKLGEVAILKGG-----RRV 628 Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGA-LWAMDRHTFRRIL 487 T FGE AL+++ R+A+V A + LW +D+ F +I+ Sbjct: 629 RTLGRHDYFGERALLHDERRSATVAANSPEVDLWVVDKDVFLQIV 673 Score = 54.4 bits (125), Expect = 1e-06 Identities = 29/103 (28%), Positives = 55/103 (53%) Frame = +2 Query: 179 FRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVH 358 F+ L Q + +A+ + +PG+ ++++G+ GD Y+I++G V + G D V Sbjct: 301 FQMLTEAQKNVITNALVVQSFKPGQPIVKEGEKGDILYIIKSGKARVSIKGKD-----VR 355 Query: 359 TYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 + FGE AL+Y+ PR+A++ A+ ++ R R+L Sbjct: 356 LLQKGDYFGERALLYDEPRSATITAEEETICVSIGRDLLDRVL 398 >UniRef50_Q4Q2R2 Cluster: Regulatory subunit of protein kinase a-like protein; n=3; Leishmania|Rep: Regulatory subunit of protein kinase a-like protein - Leishmania major Length = 648 Score = 65.3 bits (152), Expect = 8e-10 Identities = 38/144 (26%), Positives = 74/144 (51%), Gaps = 3/144 (2%) Frame = +2 Query: 92 DSDEGAPAVFPKSDAQRARLAEAVRGIL---LFRSLDAQQMQQVLDAMFEKRSEPGEYVI 262 D DE A FP + + ++ R ++ LF +LD + + M ++ E G ++ Sbjct: 335 DIDEARIASFPTTPKSQEKMKTISRVLVRHFLFSTLDDSDIAKFASIMDVEKFEAGTQIL 394 Query: 263 RQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTA 442 +G D F+++ +G + + +D E VV GS +FG+L LMY + A+V A+++ Sbjct: 395 EKGHTNDTFFIVLDGEAETTMMNEDGAEVVVPLVRGS-TFGDLGLMYEISNGAAVVARSS 453 Query: 443 GALWAMDRHTFRRILLKSAFKKRK 514 +++R T++ I ++ KR+ Sbjct: 454 VQCASLERRTYKMITSRAMEDKRR 477 >UniRef50_A0E0G1 Cluster: Chromosome undetermined scaffold_71, whole genome shotgun sequence; n=5; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_71, whole genome shotgun sequence - Paramecium tetraurelia Length = 779 Score = 64.1 bits (149), Expect = 2e-09 Identities = 34/102 (33%), Positives = 55/102 (53%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355 +F LD ++++ M+ S+ E+V +QGD F++IE G + + E+ Sbjct: 94 MFAQLDNNDKAKLIEEMYYVTSKDQEFVFKQGDKATLFFIIERGQCQITIN-----EEKK 148 Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481 + S FGELALMY+ PR+ASV A W ++R+ FR+ Sbjct: 149 RVLKPSEFFGELALMYHAPRSASVIAIGDCGFWVLERYKFRK 190 Score = 44.0 bits (99), Expect = 0.002 Identities = 28/112 (25%), Positives = 51/112 (45%), Gaps = 1/112 (0%) Frame = +2 Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334 E + + F + +Q + + + + + GE ++ +GD ++FY+I+ G V G Sbjct: 205 EFLAQVKFFDFMTEEQRDSIANVLITLKFKQGESIVNEGDMANSFYIIQKGTVQVTKQG- 263 Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGA-LWAMDRHTFRRIL 487 + + SFGE AL N R A+V+A + L ++ R IL Sbjct: 264 ----QFLRYMNQGDSFGEQALFGNCVRGATVKAHDSDVNLLSLSREDITTIL 311 >UniRef50_Q2HGG6 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 345 Score = 63.7 bits (148), Expect = 2e-09 Identities = 40/125 (32%), Positives = 68/125 (54%), Gaps = 1/125 (0%) Frame = +2 Query: 116 VFPKSDAQRARLAEA-VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFY 292 + +S R R+ E + + L +L + ++ DA+ ++ G +IR+GD G +FY Sbjct: 196 ILMESTFARRRMYEGFLEEVPLLSTLTPYERSKIADALESQKFPAGHTIIREGDPGHSFY 255 Query: 293 VIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHT 472 ++E G +G+D V H Y+ FGELAL+ + PRAASV +QT + + + Sbjct: 256 LLEAGEAVAYRSGND--TPVKH-YKKGDFFGELALLNDAPRAASVVSQTEVKVARLGKSA 312 Query: 473 FRRIL 487 F+R+L Sbjct: 313 FQRLL 317 Score = 37.5 bits (83), Expect = 0.18 Identities = 16/33 (48%), Positives = 23/33 (69%) Frame = +2 Query: 416 AASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 A + A+ LWA+DR TFRRIL++S F +R+ Sbjct: 174 ATVISAEPQCMLWALDRVTFRRILMESTFARRR 206 >UniRef50_A0YP22 Cluster: Putative uncharacterized protein; n=1; Lyngbya sp. PCC 8106|Rep: Putative uncharacterized protein - Lyngbya sp. PCC 8106 Length = 478 Score = 63.3 bits (147), Expect = 3e-09 Identities = 28/113 (24%), Positives = 66/113 (58%) Frame = +2 Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 328 L + ++ + F++ + ++Q+++ + K+ + E+++R+G+ G+ FY+I +G + + Sbjct: 311 LKDILKKVCYFKTCNDFHLRQLIELGYRKQFQASEFILREGETGERFYIILSGSVEAYLE 370 Query: 329 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 DR V++T+ FGE +LM +P+ AS+R+ L+ + +H F+ + Sbjct: 371 KVDRQIDVLNTH---NFFGEFSLMLGVPQPASIRSLEETTLFIIPKHNFQTFI 420 >UniRef50_Q4CSS9 Cluster: Protein kinase, putative; n=2; Trypanosoma cruzi|Rep: Protein kinase, putative - Trypanosoma cruzi Length = 922 Score = 62.5 bits (145), Expect = 6e-09 Identities = 38/138 (27%), Positives = 71/138 (51%), Gaps = 2/138 (1%) Frame = +2 Query: 107 APAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQ-GDDGD 283 +P V KS + + V LF ++D + ++ A+ G ++RQ G + Sbjct: 208 SPPVVAKSPEEERIVRAGVMACHLFSNMDNKDQSIIVQALKRVTFPAGTDILRQDGASVE 267 Query: 284 NFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPR-AASVRAQTAGALWAM 460 +++ G DV+ G K VHT +FGE+ +MYN+P A++R+ T L+ + Sbjct: 268 KLFLLTQGSCDVIKNG-----KRVHTLLECSTFGEMEMMYNLPTCVATIRSVTNCVLYTL 322 Query: 461 DRHTFRRILLKSAFKKRK 514 D++T++ I+L ++ KR+ Sbjct: 323 DQYTYQNIVLAASLHKRE 340 Score = 34.7 bits (76), Expect = 1.3 Identities = 23/99 (23%), Positives = 42/99 (42%) Frame = +2 Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316 +R + + + R Q+ +A+ K G+Y+IR G+ G ++I G Sbjct: 338 KREKYEALLSNVQFLREFSDYDRMQIAEALVTKTYRQGDYIIRFGETGKWMHIIVEGEVA 397 Query: 317 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 433 V+ + +++ EG GEL ++N A V A Sbjct: 398 VVGRHIGKKCEILRLKEGE-VVGELEFLFNDLTVADVIA 435 >UniRef50_Q0LLK2 Cluster: Stage II sporulation E; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Stage II sporulation E - Herpetosiphon aurantiacus ATCC 23779 Length = 570 Score = 62.1 bits (144), Expect = 7e-09 Identities = 37/108 (34%), Positives = 57/108 (52%) Frame = +2 Query: 128 SDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG 307 ++A A L E + + LF +D +Q ++ + R PGE + +GD GD+ Y++ G Sbjct: 142 TEASIAPLVEFLEQLPLFHEVDQATIQNLVQSAEHVRLAPGETLFSEGDSGDDCYIVMAG 201 Query: 308 VFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGAL 451 DV+ + G+ GE+AL+ N PRAASVRA+TA L Sbjct: 202 DVDVIKALATETILLERCRPGA-ILGEMALIDNSPRAASVRARTAATL 248 >UniRef50_UPI0000660D74 Cluster: Homolog of Homo sapiens "cGMP-dependent protein kinase 2; n=3; Coelomata|Rep: Homolog of Homo sapiens "cGMP-dependent protein kinase 2 - Takifugu rubripes Length = 93 Score = 61.7 bits (143), Expect = 1e-08 Identities = 31/92 (33%), Positives = 51/92 (55%) Frame = +2 Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334 +A+ L+ Q M Q++D MFE G+ VIR+G+ G+ YV+ G+ +V+ G Sbjct: 6 DAIMNNDFLNKLEPQHMNQMVDCMFENVYTEGQLVIREGEPGNYLYVLSEGLLEVIQNG- 64 Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVR 430 K++ +FGELA++YN R A+V+ Sbjct: 65 ----KLLGEMHAGTAFGELAILYNCKRTATVK 92 >UniRef50_Q8DKN0 Cluster: Tlr0829 protein; n=1; Synechococcus elongatus|Rep: Tlr0829 protein - Synechococcus elongatus (Thermosynechococcus elongatus) Length = 594 Score = 61.7 bits (143), Expect = 1e-08 Identities = 40/128 (31%), Positives = 67/128 (52%), Gaps = 1/128 (0%) Frame = +2 Query: 107 APAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDN 286 APA P+ L +R I F ++Q +++ + GE + R+GD GD Sbjct: 421 APAA-PEMAKAEPSLTNLLRNISCFSRCSNAELQMLIELGNREFYTVGEVICREGDPGDA 479 Query: 287 FYVIENGVFDVLVTGDDRVEKVVHT-YEGSGSFGELALMYNMPRAASVRAQTAGALWAMD 463 FY+I G +V +++ +++ T YEG FGE+A++ MPR+A+VRA L+ + Sbjct: 480 FYIILEGSVEV---RSEQLNQILATLYEGE-FFGEIAVLTGMPRSATVRALEETVLFVVH 535 Query: 464 RHTFRRIL 487 R +R+L Sbjct: 536 RAAVQRLL 543 >UniRef50_A5GVU5 Cluster: ABC-type multidrug transport system, ATPase and permease components; n=1; Synechococcus sp. RCC307|Rep: ABC-type multidrug transport system, ATPase and permease components - Synechococcus sp. (strain RCC307) Length = 718 Score = 61.7 bits (143), Expect = 1e-08 Identities = 41/127 (32%), Positives = 66/127 (51%), Gaps = 4/127 (3%) Frame = +2 Query: 119 FPKSDAQRARL-AEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYV 295 F S + R R+ A+ + I LF ++ ++ + +R PGE V R+GD D+FYV Sbjct: 576 FDISASHRVRITADRLASIPLFHGVEKAVLRWLAAEFVSERVRPGEEVFREGDPPDSFYV 635 Query: 296 IENGVFDVL---VTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDR 466 + G +VL + G +++ V E FG+ L+ + PRA +VRA+ G L +DR Sbjct: 636 VVAGTLEVLQDDLWGGVPIKQGV--VEEGDFFGDAGLLEDRPRAVTVRARGEGLLLRLDR 693 Query: 467 HTFRRIL 487 F +L Sbjct: 694 DRFLDLL 700 >UniRef50_A3IKE0 Cluster: Putative uncharacterized protein; n=1; Cyanothece sp. CCY 0110|Rep: Putative uncharacterized protein - Cyanothece sp. CCY 0110 Length = 493 Score = 61.7 bits (143), Expect = 1e-08 Identities = 34/113 (30%), Positives = 64/113 (56%) Frame = +2 Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 328 + E + + F++LD Q++++++ K + E + ++ D GD FY+I +G ++ Sbjct: 327 IKELLSKVEYFKTLDDLQIRKLIEIGTLKELKQNEILFKENDPGDAFYIILSGSVEIFTE 386 Query: 329 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 ++ ++ Y G FGELALM +PR ASV+AQ L++++ F R+L Sbjct: 387 TLNKTLAIL--YRGD-FFGELALMLGIPRTASVKAQQETILFSINNQQFDRLL 436 >UniRef50_Q4SL71 Cluster: Chromosome 17 SCAF14563, whole genome shotgun sequence; n=4; Tetraodontidae|Rep: Chromosome 17 SCAF14563, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 726 Score = 59.3 bits (137), Expect = 5e-08 Identities = 36/112 (32%), Positives = 54/112 (48%), Gaps = 1/112 (0%) Frame = +2 Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334 E ++ + F+ L + ++ D + E E GEY+IRQG GD F++I G +V Sbjct: 269 EFLKSVPTFQGLQEDILSKLADVLEETHYEDGEYIIRQGARGDTFFIISKGKVNVTREDS 328 Query: 335 DRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 E V G G FGE AL R A+V A A +DR +F+ ++ Sbjct: 329 PNGEPVYLRSLGKGDWFGEKALQGEDIRTANVIAAEAVTCLVIDRDSFKHLI 380 Score = 56.0 bits (129), Expect(2) = 1e-08 Identities = 36/130 (27%), Positives = 65/130 (50%), Gaps = 1/130 (0%) Frame = +2 Query: 47 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226 +R+++ AE + D +PKS + + EA+ ++L+ Q+Q+++D M Sbjct: 73 KRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCM 132 Query: 227 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMY 403 + +I++GD G YV+E+G +V E + G G FGELA++Y Sbjct: 133 YPVEYGKDSCIIKEGDVGSLVYVMEDGKVEV------TKESLKLCTMGPGKVFGELAILY 186 Query: 404 NMPRAASVRA 433 N R A+V++ Sbjct: 187 NCTRTATVKS 196 Score = 25.4 bits (53), Expect(2) = 1e-08 Identities = 10/28 (35%), Positives = 18/28 (64%) Frame = +2 Query: 425 VRAQTAGALWAMDRHTFRRILLKSAFKK 508 V++ T LWA+DR F+ I++++ K Sbjct: 236 VKSLTNVKLWAIDRQCFQTIMMRTGLIK 263 >UniRef50_Q8SRB5 Cluster: CAMP-DEPENDENT PROTEIN KINASE TYPE 1 REGULATORY CHAIN; n=1; Encephalitozoon cuniculi|Rep: CAMP-DEPENDENT PROTEIN KINASE TYPE 1 REGULATORY CHAIN - Encephalitozoon cuniculi Length = 312 Score = 61.3 bits (142), Expect = 1e-08 Identities = 40/157 (25%), Positives = 81/157 (51%) Frame = +2 Query: 44 NRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDA 223 +RR V++E PE + +PK + L+ + + F L+ +Q +++++ Sbjct: 79 SRRSGVYSERITPETFRLN-----YYPKDEETIRFLSSILVSDIPFGFLNPEQKTRLIES 133 Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403 + G +V+ +G+ G Y++ +G F+V G + K+ +G FGE+AL++ Sbjct: 134 TELIEIKRGTFVMHEGEIGSQMYIVASGEFEV-TKGGTLLRKLT---KGC-FFGEIALLH 188 Query: 404 NMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 N+PR A+V+A T G +W +++ +F I + +K Sbjct: 189 NIPRTATVKAVTDGKVWVVEQTSFSGIRMVDRILNKK 225 >UniRef50_Q1D8K7 Cluster: Mechanosensitive ion channel/cyclic nucleotide-binding domain protein; n=2; Cystobacterineae|Rep: Mechanosensitive ion channel/cyclic nucleotide-binding domain protein - Myxococcus xanthus (strain DK 1622) Length = 525 Score = 60.9 bits (141), Expect = 2e-08 Identities = 44/129 (34%), Positives = 69/129 (53%), Gaps = 6/129 (4%) Frame = +2 Query: 116 VFPKSDAQRARLAE-AVRGIL----LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDG 280 V + + R L+E +R +L LF+SLD +++ ++ +R GE +I++GD+G Sbjct: 343 VHVRQEMARTELSEDTIRSLLGAVDLFQSLDTEELDRLRQESLVRRFGAGERIIQEGDEG 402 Query: 281 DNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWA 457 FYV+ +G V TG + E T G GS FGE+ L+ R+A+V A L Sbjct: 403 RTFYVLASGEVSVR-TGKSQSEV---TRLGRGSYFGEMCLLTGERRSATVVAVEDSLLLE 458 Query: 458 MDRHTFRRI 484 +DR TF R+ Sbjct: 459 VDRPTFARL 467 >UniRef50_A4TWF8 Cluster: Na+/H+ Antiporter; n=1; Magnetospirillum gryphiswaldense|Rep: Na+/H+ Antiporter - Magnetospirillum gryphiswaldense Length = 868 Score = 60.9 bits (141), Expect = 2e-08 Identities = 36/114 (31%), Positives = 64/114 (56%), Gaps = 1/114 (0%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340 V G+ LF++L +Q+ +++D + + PG+++IR+G+ GD + + +G +V T +R Sbjct: 730 VEGVPLFKTLSPEQLSRIIDLLHPMLAVPGDFIIRKGEVGDGMFFVASGAVEVR-TETNR 788 Query: 341 VEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSA 499 + + GSG FGE+AL+ + PR A V A +L + F +L SA Sbjct: 789 LRR------GSGDFFGEMALLSHAPRNADVVALGFCSLLVLHARDFSALLNTSA 836 >UniRef50_Q9M8S6 Cluster: Potassium channel SKOR (Stelar K(+) outward rectifying channel); n=25; Magnoliophyta|Rep: Potassium channel SKOR (Stelar K(+) outward rectifying channel) - Arabidopsis thaliana (Mouse-ear cress) Length = 828 Score = 59.3 bits (137), Expect = 5e-08 Identities = 29/109 (26%), Positives = 58/109 (53%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340 + + LFR ++ + Q++ + E+ PGE ++ QG D Y + +GV + + D Sbjct: 398 IEKVPLFRGCSSEFINQIVIRLHEEFFLPGEVIMEQGSVVDQLYFVCHGVLEEIGITKDG 457 Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 E++V + SFGE++++ N+P+ +VR + +D+ +F IL Sbjct: 458 SEEIVAVLQPDHSFGEISILCNIPQPYTVRVAELCRILRLDKQSFMNIL 506 >UniRef50_Q8CXT1 Cluster: CAMP-dependent protein kinase regulatory chain; n=4; Leptospira|Rep: CAMP-dependent protein kinase regulatory chain - Leptospira interrogans Length = 719 Score = 58.8 bits (136), Expect = 7e-08 Identities = 36/134 (26%), Positives = 68/134 (50%), Gaps = 2/134 (1%) Frame = +2 Query: 110 PAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNF 289 P + P + L + + I +F ++ ++ L + E+R + G+ +IR+G GD F Sbjct: 450 PEITPPKHIEAYNLLDVLTQIDIFHGFPIEKAKEFLLIVNEERYKRGDQIIRKGTPGDKF 509 Query: 290 YVIENG--VFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMD 463 Y+I +G F+ L D+ + + Y FGE +L+ ++PRAA V A+T ++ Sbjct: 510 YIIASGNVKFEGL-NQDETGQGPIKRYGTYEYFGEASLVLDLPRAADVYAETDVLALTIE 568 Query: 464 RHTFRRILLKSAFK 505 ++ F + + S K Sbjct: 569 KNKFLQFIRNSDLK 582 >UniRef50_Q2VWB6 Cluster: CAMP-dependent protein kinase A regulatory subunit; n=2; Giardia intestinalis|Rep: CAMP-dependent protein kinase A regulatory subunit - Giardia lamblia (Giardia intestinalis) Length = 460 Score = 58.8 bits (136), Expect = 7e-08 Identities = 39/130 (30%), Positives = 70/130 (53%), Gaps = 2/130 (1%) Frame = +2 Query: 131 DAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGV 310 +A+ R +R + + + L ++ + A + G+ ++ QGD+G+ FY IE+G Sbjct: 335 EAEIQRYIGFLRHVEVLKQLRENELFALAQACTPEYYIDGQDIVTQGDEGNTFYFIEDGR 394 Query: 311 FDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL- 487 DV+V+ D +V ++ + FGE AL+ N PR A+ R+ + A+DR +F +L Sbjct: 395 VDVIVS-DHKVAEL----SSNSYFGEAALLNNAPRNATCRSVGETKVAALDRESFDNLLG 449 Query: 488 -LKSAFKKRK 514 LKS ++ K Sbjct: 450 PLKSILERPK 459 Score = 38.7 bits (86), Expect = 0.078 Identities = 36/141 (25%), Positives = 66/141 (46%), Gaps = 20/141 (14%) Frame = +2 Query: 116 VFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEP-GEYVIRQGDDGDNFY 292 V K+ + A + +A+ L + ++ ++Q L ++ + P G +I+QGD GD FY Sbjct: 188 VLEKTPEETALILKALNSSALTETY-SRDVKQALASVLKLIDCPMGTVLIKQGDPGDYFY 246 Query: 293 VIENGVFDVLVTGD----------------DRVEKV---VHTYEGSGSFGELALMYNMPR 415 +++ G ++ T + + V+K+ V+ G+LAL+Y PR Sbjct: 247 IMKTGHCNIYKTENVPPETVSVPDNTLDPAECVQKLGPQVNEVLPGVGVGDLALLYGAPR 306 Query: 416 AASVRAQTAGALWAMDRHTFR 478 AA+V + WA+ FR Sbjct: 307 AATVITTVESSFWAIHGTDFR 327 >UniRef50_Q5QFC4 Cluster: EnvDll2-01; n=1; Oikopleura dioica|Rep: EnvDll2-01 - Oikopleura dioica (Tunicate) Length = 703 Score = 58.4 bits (135), Expect = 9e-08 Identities = 33/101 (32%), Positives = 55/101 (54%), Gaps = 1/101 (0%) Frame = +2 Query: 188 LDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYE 367 L ++++ D + E+R + + +I+QG+ GDNFY+I G + V D EK V + Sbjct: 280 LKESNLRKIADCLEEERFDDKDPIIKQGEVGDNFYIIRTGSVRITVNTDGDEEKEV-AVK 338 Query: 368 GSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 G G FGE AL+ + R+A+V A + +DR F ++ Sbjct: 339 GEGEFFGEKALLTSDTRSANVYAVGDVVCYTLDRSAFTNLI 379 Score = 58.0 bits (134), Expect = 1e-07 Identities = 39/131 (29%), Positives = 67/131 (51%), Gaps = 3/131 (2%) Frame = +2 Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVI--RQGDDGDNFYVI 298 K+ QR + +A+ R L Q+ ++DAM + E +I R+ GD ++I Sbjct: 140 KTAEQRKLIKDALLKNSFMRGLSEDQLNMLIDAMSKIDYPATEKIIKDRENTTGDEMFII 199 Query: 299 ENGVFDVLVTGDDRVEKVVHTYE-GSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTF 475 E+G +V ++ D H + SG FGELA+MYN R A++ ++T LW + R F Sbjct: 200 EDG--EVTISKDG-----THITDIKSGLFGELAIMYNCQRTATITSKTDVTLWKLHRTAF 252 Query: 476 RRILLKSAFKK 508 + ++ + +K Sbjct: 253 QTVVKAAGEEK 263 >UniRef50_A7C147 Cluster: cGMP-dependent protein kinase type I; n=1; Beggiatoa sp. PS|Rep: cGMP-dependent protein kinase type I - Beggiatoa sp. PS Length = 387 Score = 58.0 bits (134), Expect = 1e-07 Identities = 36/118 (30%), Positives = 64/118 (54%), Gaps = 2/118 (1%) Frame = +2 Query: 146 RLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV 325 R + +R R L A+ + + + M +++ GE ++R+G+ GD FY+I++G ++ Sbjct: 131 RRMDKLRHFPALRRLPAESIYEAVHRMKIIKAKAGEIIVREGELGDAFYLIDSGRVEIWQ 190 Query: 326 TG--DDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLK 493 TG DD+ +V EG +FGE AL+ R A+VR G L +++ F ++ K Sbjct: 191 TGFYDDKPTRVTELGEGD-AFGEDALVTGGRRNATVRMIEEGQLLILEQSDFIELISK 247 >UniRef50_A3YU60 Cluster: Putative glutaminase; n=1; Synechococcus sp. WH 5701|Rep: Putative glutaminase - Synechococcus sp. WH 5701 Length = 620 Score = 57.6 bits (133), Expect = 2e-07 Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 4/100 (4%) Frame = +2 Query: 188 LDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT--GDD--RVEKVV 355 L Q + D M + GE+V+++GD G +++ G F + V G D + Sbjct: 482 LQPTHRQTLADLMQCRNFAKGEHVVKKGDPGHELFLVREGRFTITVELRGSDGQTYASRL 541 Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTF 475 T+E FGE+A + PR A+V A G+ W ++RH F Sbjct: 542 ATFEPGMCFGEIAFLSGTPRTANVTADLDGSCWVLERHDF 581 >UniRef50_Q10V66 Cluster: Cyclic nucleotide-binding protein; n=2; Oscillatoriales|Rep: Cyclic nucleotide-binding protein - Trichodesmium erythraeum (strain IMS101) Length = 454 Score = 57.2 bits (132), Expect = 2e-07 Identities = 28/111 (25%), Positives = 60/111 (54%) Frame = +2 Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334 E + + +F+ + +++++ A+ + P EY+IR+G+ G+ Y I+ G+ V Sbjct: 323 EVIEKVPIFQGSTSHFVEEIVIALKPEIVPPNEYIIREGNLGNEMYFIKRGLVQVF---S 379 Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 ++ + T E FGE++L+Y R AS+ T L+ + ++ F+++L Sbjct: 380 EKTGSIYRTMEAGTFFGEISLVYEKRRTASIITLTYCELFILYKNDFKKVL 430 >UniRef50_Q9Y3Q4 Cluster: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4; n=41; Euteleostomi|Rep: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 - Homo sapiens (Human) Length = 1203 Score = 57.2 bits (132), Expect = 2e-07 Identities = 35/117 (29%), Positives = 58/117 (49%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340 V + LF + D + +L + + +PG+Y+IR+G G Y I++GV VL G+ Sbjct: 590 VASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKE 649 Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511 + +Y FGE+ L+ R ASVRA T L+++ F +L + +R Sbjct: 650 TKLADGSY-----FGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRR 701 >UniRef50_Q4S874 Cluster: Chromosome 5 SCAF14709, whole genome shotgun sequence; n=5; Clupeocephala|Rep: Chromosome 5 SCAF14709, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1512 Score = 56.8 bits (131), Expect = 3e-07 Identities = 37/117 (31%), Positives = 59/117 (50%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340 V + LF + D + +L + + +PG+Y+IR+G G Y I++GV VL G+ Sbjct: 704 VASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGN-- 761 Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511 K +GS FGE+ L+ R ASVRA T L+++ F +L + +R Sbjct: 762 --KETKLSDGS-YFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRR 815 Score = 40.7 bits (91), Expect = 0.019 Identities = 21/71 (29%), Positives = 37/71 (52%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340 V + LF + D + +L + + +PG+Y+IR+G G Y I++GV VL G+ Sbjct: 562 VASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKE 621 Query: 341 VEKVVHTYEGS 373 + +Y G+ Sbjct: 622 TKLSDGSYFGA 632 >UniRef50_Q3W7N0 Cluster: Cyclic nucleotide-binding domain:Peptidase M50 precursor; n=1; Frankia sp. EAN1pec|Rep: Cyclic nucleotide-binding domain:Peptidase M50 precursor - Frankia sp. EAN1pec Length = 968 Score = 56.8 bits (131), Expect = 3e-07 Identities = 39/137 (28%), Positives = 66/137 (48%), Gaps = 2/137 (1%) Frame = +2 Query: 89 DDSDEGAPAVFPKSDAQ-RARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIR 265 D SD AP + +++ RA + G LF L + +L + + GE V+ Sbjct: 594 DFSDRLAPLLARRAENDTRADERAELEGFALFDGLRTRDKDTLLAHLRARSCVDGEVVVA 653 Query: 266 QGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF-GELALMYNMPRAASVRAQTA 442 +GD G FY++ +G + T D + + G+G F GE AL+++ P AA+ + Sbjct: 654 EGDPGSAFYLVRSGAVALAQTCVDGPPRTL----GAGEFFGESALLHDEPHAATATSVGE 709 Query: 443 GALWAMDRHTFRRILLK 493 LW +DR TF ++ + Sbjct: 710 TRLWELDRTTFDDVVCR 726 >UniRef50_Q0VQV6 Cluster: Cyclic nucleotide-binding domain protein; n=1; Alcanivorax borkumensis SK2|Rep: Cyclic nucleotide-binding domain protein - Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) Length = 357 Score = 56.8 bits (131), Expect = 3e-07 Identities = 35/111 (31%), Positives = 53/111 (47%), Gaps = 1/111 (0%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT-GDDRVEKV 352 LF + + + + R + GE +IRQG+ D Y+++ GV +V + G+ V Sbjct: 148 LFHRVPPSNILGIFSRLKANRHKEGERIIRQGEAADCCYILKEGVCEVSINIGEGEPTSV 207 Query: 353 VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFK 505 EG FGE AL+ PR A+V T G L +DR F +L + K Sbjct: 208 AMLEEGEW-FGEEALLSGKPRNATVSMATDGVLMRLDRQDFDALLREPIIK 257 >UniRef50_UPI0000EC9F34 Cluster: UPI0000EC9F34 related cluster; n=1; Gallus gallus|Rep: UPI0000EC9F34 UniRef100 entry - Gallus gallus Length = 747 Score = 56.4 bits (130), Expect = 4e-07 Identities = 36/117 (30%), Positives = 60/117 (51%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340 V + LF + D + +L + + +PG+Y+IR+G G Y I++GV +L G+ Sbjct: 392 VASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSILTKGN-- 449 Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511 K + +GS FGE+ L+ R ASVRA T L+++ F +L + +R Sbjct: 450 --KEMKLSDGS-YFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRR 503 >UniRef50_Q6WL05 Cluster: Hyperpolarization-activated ion channel; n=10; Pancrustacea|Rep: Hyperpolarization-activated ion channel - Panulirus argus (Spiny lobster) Length = 691 Score = 56.4 bits (130), Expect = 4e-07 Identities = 33/110 (30%), Positives = 60/110 (54%), Gaps = 1/110 (0%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340 V + F + DA+ + V+ + + +PG+ +I++G G+ Y I+ G+ D++++ + Sbjct: 429 VASVPFFANADARFVTDVVTKLRYEVYQPGDIIIKEGTIGNKMYFIQEGIVDIVMSNGE- 487 Query: 341 VEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 V T GS FGE+ L+ N R ASVRA+T L+++ F +L Sbjct: 488 ----VATSLSDGSYFGEICLLTNARRTASVRAETYCNLFSLSVEHFNTVL 533 >UniRef50_A5G0B9 Cluster: Putative transcriptional regulator, Crp/Fnr family; n=1; Acidiphilium cryptum JF-5|Rep: Putative transcriptional regulator, Crp/Fnr family - Acidiphilium cryptum (strain JF-5) Length = 227 Score = 56.0 bits (129), Expect = 5e-07 Identities = 31/106 (29%), Positives = 55/106 (51%) Frame = +2 Query: 170 ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEK 349 I LF +++ + +E+ GE +I++GD G + +I G V++ G D ++ Sbjct: 12 IPLFAPFSPEELDALYACTYERNMTTGEMLIQRGDPGTSMMLILAGEVRVVLPGIDGNDQ 71 Query: 350 VVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 ++T FGE+AL PR+A V A T G L ++R + R++ Sbjct: 72 DLNTLREGAVFGEIALFDGKPRSADVVAATNGRLLVLERASVVRLI 117 >UniRef50_A0LNC0 Cluster: Cyclic nucleotide-binding protein; n=1; Syntrophobacter fumaroxidans MPOB|Rep: Cyclic nucleotide-binding protein - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 171 Score = 56.0 bits (129), Expect = 5e-07 Identities = 35/138 (25%), Positives = 73/138 (52%) Frame = +2 Query: 80 PEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYV 259 P E +S E APA + + + + E +R + +F + +++ + + GE++ Sbjct: 4 PTERNS-ECAPASRGRCELEDS--LEILRNVSVFAGIPLPRLKLYAYLSRKMCFQAGEFL 60 Query: 260 IRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 439 QGD GD Y++ +G V+ + ++H ++ FG +AL+ ++ R SVRA T Sbjct: 61 FHQGDSGDRGYIVISGRLQVIRELKEH-SVLLHEFKPGDFFGGMALLSDVNRLFSVRAVT 119 Query: 440 AGALWAMDRHTFRRILLK 493 + ++DR +FR+++++ Sbjct: 120 SAECLSLDRESFRKLMIQ 137 >UniRef50_Q23EB7 Cluster: Cyclic nucleotide-binding domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 1079 Score = 56.0 bits (129), Expect = 5e-07 Identities = 28/114 (24%), Positives = 60/114 (52%), Gaps = 2/114 (1%) Frame = +2 Query: 152 AEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTG 331 ++ ++ +F+ Q + +++ M E PGE + +GD D+ Y+I NG ++ ++G Sbjct: 504 SQIIKKFDIFKCFSQQTINKLVFLMKEIIVSPGETIFLEGDLDDSVYLILNGQIEIFISG 563 Query: 332 --DDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 ++ K++ + FGE+A PR+AS ++ L+ ++R F +I+ Sbjct: 564 NQNNSQTKILKDLSNNQIFGEIAFFCQKPRSASAKSIVLSTLYKIERKDFMQII 617 >UniRef50_Q2LV90 Cluster: CAMP-dependent transcriptional regulator; n=2; Syntrophus aciditrophicus SB|Rep: CAMP-dependent transcriptional regulator - Syntrophus aciditrophicus (strain SB) Length = 249 Score = 55.6 bits (128), Expect = 6e-07 Identities = 29/114 (25%), Positives = 55/114 (48%) Frame = +2 Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334 + ++ I LF S + +++ + + + + GE + +GD G F++I NG+ + V+ Sbjct: 28 DLLKAIPLFESFNNSELRHLASLLKGQSLDKGEILFHKGDTGSAFFIIANGLIRISVSNK 87 Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKS 496 E G FGE+AL+ R+A A L+ +DR+ F L ++ Sbjct: 88 AGDEVTFAHLRGGDFFGEMALLDEQTRSADATALEDSTLYVLDRNDFFPFLFEN 141 >UniRef50_Q0F2T2 Cluster: Glucose-6-phosphate 1-dehydrogenase; n=1; Mariprofundus ferrooxydans PV-1|Rep: Glucose-6-phosphate 1-dehydrogenase - Mariprofundus ferrooxydans PV-1 Length = 665 Score = 55.6 bits (128), Expect = 6e-07 Identities = 32/81 (39%), Positives = 45/81 (55%) Frame = +2 Query: 248 GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASV 427 G+ + R G +G Y+IE G DV+ D VV T G FGEL+L+ R ASV Sbjct: 558 GDEIARLGTEGRELYIIEMGSVDVI----DPEGNVVTTLSGGQVFGELSLLVTKERRASV 613 Query: 428 RAQTAGALWAMDRHTFRRILL 490 RA T AL+ M++ F ++L+ Sbjct: 614 RAVTYCALYMMEKRDFCKVLM 634 >UniRef50_Q08V69 Cluster: PKA regulatory subunit-like protein; n=1; Stigmatella aurantiaca DW4/3-1|Rep: PKA regulatory subunit-like protein - Stigmatella aurantiaca DW4/3-1 Length = 450 Score = 55.6 bits (128), Expect = 6e-07 Identities = 34/105 (32%), Positives = 51/105 (48%) Frame = +2 Query: 170 ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEK 349 I LF SL + ++L + + GE ++++G G + +VI G +V+ G + Sbjct: 177 IPLFASLGREMFLEMLAGVERSVFQRGERILQEGAPGSSMFVIVEGEVNVVRQGQEGQPL 236 Query: 350 VVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484 V T G FGE+AL+Y +PR ASV A T L R I Sbjct: 237 TVATLGEGGFFGEMALLYPVPRLASVVAGTRTVLLEFSRERMEDI 281 Score = 33.9 bits (74), Expect = 2.2 Identities = 28/114 (24%), Positives = 45/114 (39%) Frame = +2 Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 328 LA +R LLF + + V +A GE ++ +G Y + G V Sbjct: 301 LANVLRSNLLFAAWPEALQRGVAEAFTPVAVPAGEELLTRGHPAHQLYFLLRGHCTVFHK 360 Query: 329 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILL 490 D E FGE++L+ + ASVR T L +++ R+L+ Sbjct: 361 HLDGHETAYPGMNEGAVFGEVSLLRSRLVTASVRTTTPCVLLKLEQTHLERLLM 414 >UniRef50_A7BXC8 Cluster: MscS Mechanosensitive ion channel; n=1; Beggiatoa sp. PS|Rep: MscS Mechanosensitive ion channel - Beggiatoa sp. PS Length = 564 Score = 55.6 bits (128), Expect = 6e-07 Identities = 29/84 (34%), Positives = 45/84 (53%) Frame = +2 Query: 236 RSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPR 415 R PG+ +++QGD GD+ ++I GV VLV DD K V FGE+AL+ R Sbjct: 424 RFNPGDTIVQQGDAGDSLFIIVEGVVSVLVQTDDGRTKEVARLGAGNFFGEMALLTGEER 483 Query: 416 AASVRAQTAGALWAMDRHTFRRIL 487 A+V+A L+ + + R ++ Sbjct: 484 MATVKALVDTYLFELTKADIRPLI 507 >UniRef50_Q2RX44 Cluster: Cyclic nucleotide-binding domain (CNMP-BD) protein; n=1; Rhodospirillum rubrum ATCC 11170|Rep: Cyclic nucleotide-binding domain (CNMP-BD) protein - Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255) Length = 129 Score = 55.2 bits (127), Expect = 8e-07 Identities = 31/84 (36%), Positives = 43/84 (51%) Frame = +2 Query: 248 GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASV 427 G V R+GD D Y++E+G+ D++V D E V+ T FGE+AL+ PR A+ Sbjct: 20 GAVVFREGDAADGVYLVESGLVDMIVRRPDGSEAVIGTVGAGEVFGEMALIDGHPRMATA 79 Query: 428 RAQTAGALWAMDRHTFRRILLKSA 499 R L + F R LKSA Sbjct: 80 RVAMEATLVRVSNEAF-RAQLKSA 102 >UniRef50_Q695H0 Cluster: CGMP-dependent protein kinase; n=1; Chlamydomonas reinhardtii|Rep: CGMP-dependent protein kinase - Chlamydomonas reinhardtii Length = 1027 Score = 55.2 bits (127), Expect = 8e-07 Identities = 37/132 (28%), Positives = 67/132 (50%), Gaps = 15/132 (11%) Frame = +2 Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQG---DDGDNFYVIENGVFDV 319 + EA++ +F+ + + +V+ M+ + G V++QG D Y ++ G +V Sbjct: 157 ILEALKRNFVFKGIPQNHLVEVVGRMYGISFKSGAVVLQQGALPKQDDCMYYLQQGEAEV 216 Query: 320 LVTGDDRVEK-----------VVHTYEGSG-SFGELALMYNMPRAASVRAQTAGALWAMD 463 +++G K V + G FG++AL+++ PR ASV A+T +WAMD Sbjct: 217 VISGGADASKNHGEERKVDGHTVRIPQKPGWLFGDVALLFHSPRTASVVAKTNITVWAMD 276 Query: 464 RHTFRRILLKSA 499 R TF + ++K A Sbjct: 277 RRTFLKFVMKHA 288 Score = 46.4 bits (105), Expect = 4e-04 Identities = 29/87 (33%), Positives = 46/87 (52%), Gaps = 4/87 (4%) Frame = +2 Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSE--PGEYVIRQGDDGDNFYVIENGVFDVL 322 ++ +R + F+ L +QM+ +LD F+ R E G+ ++ QGD + YV++ G L Sbjct: 418 VSAVIRSLPQFKGLKQEQMENILD-RFDAREELMQGDTILNQGDMLEKLYVVKIGEI-AL 475 Query: 323 VTGDDRVE--KVVHTYEGSGSFGELAL 397 D+RVE VH G FGE A+ Sbjct: 476 FRNDERVEDPNFVHEIAGFSYFGETAI 502 >UniRef50_UPI0000383B9A Cluster: COG0642: Signal transduction histidine kinase; n=1; Magnetospirillum magnetotacticum MS-1|Rep: COG0642: Signal transduction histidine kinase - Magnetospirillum magnetotacticum MS-1 Length = 385 Score = 54.8 bits (126), Expect = 1e-06 Identities = 29/105 (27%), Positives = 54/105 (51%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355 LF D + +++++ E GE + R+GD GD+ YV+ +G ++ V V+ Sbjct: 16 LFTVQDEETLKRIIACGSEVLLSDGECLFRKGDMGDSIYVVLDGAIEISVQDGGGEFHVM 75 Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILL 490 + E FGE+A++ N+PR A+ A+ L + F +I++ Sbjct: 76 NVLEVGSLFGEVAILDNLPRTANAAARGGAHLLRITGGDFHQIMI 120 >UniRef50_Q4RR21 Cluster: Chromosome 14 SCAF15003, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 14 SCAF15003, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 621 Score = 54.8 bits (126), Expect = 1e-06 Identities = 27/80 (33%), Positives = 43/80 (53%) Frame = +2 Query: 188 LDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYE 367 LD +Q ++D + +PG +VI++G +GD+ Y++ G V G D + T Sbjct: 16 LDDEQTAMMVDLLAVSNFKPGSHVIKEGSEGDSMYIVAGGQLQVTQAGRD-----LRTLT 70 Query: 368 GSGSFGELALMYNMPRAASV 427 FGELA++YN R A+V Sbjct: 71 TGDVFGELAILYNCKRTATV 90 Score = 48.0 bits (109), Expect = 1e-04 Identities = 30/122 (24%), Positives = 62/122 (50%), Gaps = 1/122 (0%) Frame = +2 Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 304 KS +R +L ++ + L+ Q+ +++D+M E + + + ++R+G + + FY+I Sbjct: 147 KSKKRREQLMGFLKMSQTLKDLNNVQLSKIIDSMEEVKYQDKDVIVREGAEANTFYIILK 206 Query: 305 GVFDVLVTGD-DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481 G +VLVT + + +K + FGE AL+ + R A+ A + +D+ F Sbjct: 207 G--EVLVTKNVNGHQKQIRRMGKGEHFGEQALIREVLRTATCTADGPVTCFTIDKEVFEE 264 Query: 482 IL 487 + Sbjct: 265 TI 266 >UniRef50_Q2S6T5 Cluster: CAMP-binding protein-catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; n=1; Hahella chejuensis KCTC 2396|Rep: CAMP-binding protein-catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase - Hahella chejuensis (strain KCTC 2396) Length = 360 Score = 54.8 bits (126), Expect = 1e-06 Identities = 34/105 (32%), Positives = 62/105 (59%), Gaps = 1/105 (0%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEK-RSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKV 352 LF +L +++V A FE+ + G+ +I +GD+GD FY++ +G V++ GD+ K Sbjct: 167 LFFNLPPANVEKVF-ARFERIEVKKGQVIIEEGDEGDYFYLLIDGSARVVIGGDE--SKP 223 Query: 353 VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 + +GS FGE AL+ + R+A++ G L +D+ +F+ +L Sbjct: 224 IRVSKGS-YFGEEALVSDTVRSATIIMSEDGVLARLDKKSFQSLL 267 >UniRef50_A0DBC7 Cluster: Chromosome undetermined scaffold_44, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_44, whole genome shotgun sequence - Paramecium tetraurelia Length = 495 Score = 54.8 bits (126), Expect = 1e-06 Identities = 37/123 (30%), Positives = 58/123 (47%), Gaps = 6/123 (4%) Frame = +2 Query: 137 QRARLAEAVRGILLFRSLDAQQMQ---QVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG 307 Q +L E + I F L + Q + DA+ K E + +QGD GD FY++ G Sbjct: 38 QAIKLQELLSTIKYFAQLFQSKQQLIYDIADALQYKFVHQNEIIFKQGDQGDMFYIVLQG 97 Query: 308 VFDVLVT---GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFR 478 + + D V K V T GSFGELAL + R A+ + T +D+ T++ Sbjct: 98 TVSIQINIPQEDVFVPKEVATITEGGSFGELALQSSQARTATSISVTDCHFATIDKTTYK 157 Query: 479 RIL 487 +++ Sbjct: 158 QLI 160 >UniRef50_Q09BB2 Cluster: Cyclic nucleotide-binding:Bacterial regulatory protein, Crp; n=2; Stigmatella aurantiaca DW4/3-1|Rep: Cyclic nucleotide-binding:Bacterial regulatory protein, Crp - Stigmatella aurantiaca DW4/3-1 Length = 226 Score = 54.4 bits (125), Expect = 1e-06 Identities = 31/107 (28%), Positives = 55/107 (51%), Gaps = 1/107 (0%) Frame = +2 Query: 170 ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEK 349 I LF +L A+ ++ + + + G+ + +QGD+G + Y++ G + + + E Sbjct: 10 IPLFENLQAEDLEHLSTLLHTRHCAKGDVIFQQGDEGADLYIVRAGQVAIRLHSPEGKE- 68 Query: 350 VVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 V+ T GSG FGEL+L+ PR+ A+ L ++ R F R L Sbjct: 69 VILTLLGSGEVFGELSLLDGEPRSTHAVAREETVLLSLRREDFHRFL 115 >UniRef50_A0YAY7 Cluster: CAMP-binding protein-catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; n=1; marine gamma proteobacterium HTCC2143|Rep: CAMP-binding protein-catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase - marine gamma proteobacterium HTCC2143 Length = 361 Score = 54.4 bits (125), Expect = 1e-06 Identities = 34/109 (31%), Positives = 57/109 (52%), Gaps = 1/109 (0%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVE-KV 352 LF + ++++LD + G+ ++RQG+ GD Y I+ GV V +++ + Sbjct: 154 LFYKVPPMNIRKILDKFSAHYASAGDTILRQGELGDCCYYIKEGVAGVYQAENEKSSPSL 213 Query: 353 VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSA 499 V + FGE AL+ + PR A++ T G L +D+ F +LLKSA Sbjct: 214 VAELDVGRCFGEDALVNDAPRNATITMHTNGVLMRLDKRDF-FLLLKSA 261 >UniRef50_A0GWU5 Cluster: Stage II sporulation E; n=2; Chloroflexus|Rep: Stage II sporulation E - Chloroflexus aggregans DSM 9485 Length = 563 Score = 54.4 bits (125), Expect = 1e-06 Identities = 30/113 (26%), Positives = 58/113 (51%) Frame = +2 Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 328 + + +R + LF+++ + + + E R PGE + QGD G YV+ +G +V +T Sbjct: 139 MLDRLRSLPLFQAVPEAVLSALAPRLAECRLAPGEVLFHQGDTGHECYVVLSGAVEV-IT 197 Query: 329 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 + E + + GE++L+ + PR+A+VRA L A++ F ++ Sbjct: 198 FVNGAELRLEVFHSGQIIGEMSLIDHSPRSATVRAIEPSRLVALNEQVFATLI 250 >UniRef50_Q3MD80 Cluster: Cyclic nucleotide-binding domain (CNMP-BD) protein; n=1; Anabaena variabilis ATCC 29413|Rep: Cyclic nucleotide-binding domain (CNMP-BD) protein - Anabaena variabilis (strain ATCC 29413 / PCC 7937) Length = 408 Score = 54.0 bits (124), Expect = 2e-06 Identities = 28/83 (33%), Positives = 45/83 (54%) Frame = +2 Query: 185 SLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTY 364 +L +Q+ Q+L + +PGE VI QGD D FY++ G +V+ D K++ Sbjct: 236 TLTDKQLIQLLPQLKMLTFQPGEIVIHQGDLADKFYILMEGEVEVIQEDGDSEPKLLKRL 295 Query: 365 EGSGSFGELALMYNMPRAASVRA 433 + FGE+ L++ R A+VRA Sbjct: 296 GPNSYFGEIGLLHETTRTATVRA 318 >UniRef50_Q5WUW4 Cluster: Putative uncharacterized protein; n=4; Legionella pneumophila|Rep: Putative uncharacterized protein - Legionella pneumophila (strain Lens) Length = 153 Score = 53.6 bits (123), Expect = 3e-06 Identities = 27/107 (25%), Positives = 54/107 (50%), Gaps = 5/107 (4%) Frame = +2 Query: 173 LLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV-----TGDD 337 +LF+ +D + + + L+ E GE++ Q + GD+ Y++E G +++ D Sbjct: 10 MLFKGVDGKYIDEFLENCEEVELPQGEFLFHQNEIGDSMYIVEQGELQIILEQNSTDSDT 69 Query: 338 RVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFR 478 + E+++ ++ GEL + + RAAS+RA L ++ FR Sbjct: 70 KEEQLIGVFKSGSLVGELCVFGQLKRAASIRALADCRLLKIEGEDFR 116 >UniRef50_P74736 Cluster: CAMP protein kinase regulatory chain; n=2; Chroococcales|Rep: CAMP protein kinase regulatory chain - Synechocystis sp. (strain PCC 6803) Length = 434 Score = 53.6 bits (123), Expect = 3e-06 Identities = 34/107 (31%), Positives = 53/107 (49%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355 + +L Q+ Q+ + + P E + R+GD GD FY I G DV G V ++ Sbjct: 139 VMNALPEQERHQLAGLLTPHHAYPREVLCREGDQGDYFYFIGGGEADV-YKGTTWVNRLT 197 Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKS 496 FGE++L+ PR+A+V A T L+ +D+ F IL +S Sbjct: 198 ----SGDIFGEMSLLTGEPRSATVVAVTPMELYQLDKENFANILSQS 240 >UniRef50_A5UY70 Cluster: Cyclic nucleotide-binding protein; n=3; Chloroflexaceae|Rep: Cyclic nucleotide-binding protein - Roseiflexus sp. RS-1 Length = 388 Score = 53.6 bits (123), Expect = 3e-06 Identities = 30/86 (34%), Positives = 43/86 (50%), Gaps = 2/86 (2%) Frame = +2 Query: 245 PGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAAS 424 PG +I QG DNFY+I G +V + D E +V+ FGE+ L++ R A Sbjct: 277 PGAVIIEQGSPADNFYIITRGDVEVFIEHPDGGEIIVNHLSTGSYFGEIGLLHQGRRTAG 336 Query: 425 VRAQTAGALWA--MDRHTFRRILLKS 496 VRA A A +D+ F +L +S Sbjct: 337 VRASFATGCDAAVLDQQEFHTLLAES 362 >UniRef50_A5PH37 Cluster: AKT2 inward rectifier channel; n=6; Embryophyta|Rep: AKT2 inward rectifier channel - Physcomitrella patens (Moss) Length = 967 Score = 53.6 bits (123), Expect = 3e-06 Identities = 35/132 (26%), Positives = 60/132 (45%), Gaps = 3/132 (2%) Frame = +2 Query: 101 EGAPAVFPK---SDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQG 271 +G AV PK S + E V + LF + Q++ M + P E +I Sbjct: 361 QGTMAVLPKAIRSSIAQYLFLETVEKVYLFHGTSYNFLTQLVTEMKAEYFPPREEIILFN 420 Query: 272 DDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGAL 451 + FY++ NG DV +T D E+++ T GE+ ++ MP+ +VR++ L Sbjct: 421 EAPSEFYIVVNGSVDV-ITMKDASEQILFTAVTGDVIGEIGVLCYMPQPFTVRSRKLSQL 479 Query: 452 WAMDRHTFRRIL 487 +DR F ++ Sbjct: 480 LRLDRSVFMNVV 491 >UniRef50_O76977 Cluster: Hyperpolarization-activated (Ih) channel; n=5; Eumetazoa|Rep: Hyperpolarization-activated (Ih) channel - Strongylocentrotus purpuratus (Purple sea urchin) Length = 767 Score = 53.6 bits (123), Expect = 3e-06 Identities = 31/122 (25%), Positives = 62/122 (50%), Gaps = 1/122 (0%) Frame = +2 Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 304 + D + V + F D+ + +V+ + + +P +YVI++G GD + I+ Sbjct: 528 RQDVANYNCRDLVASVPFFVGADSNFVTRVVTLLEFEVFQPADYVIQEGTFGDRMFFIQQ 587 Query: 305 GVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481 G+ D++++ + V+ T GS FGE+ L+ R ASV+ +T L+++ F + Sbjct: 588 GIVDIIMS-----DGVIATSLSDGSYFGEICLLTRERRVASVKCETYCTLFSLSVQHFNQ 642 Query: 482 IL 487 +L Sbjct: 643 VL 644 >UniRef50_A0DKC6 Cluster: Chromosome undetermined scaffold_54, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_54, whole genome shotgun sequence - Paramecium tetraurelia Length = 503 Score = 53.6 bits (123), Expect = 3e-06 Identities = 35/97 (36%), Positives = 51/97 (52%), Gaps = 2/97 (2%) Frame = +2 Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT--GDDRVEKVVHTYEGSGSFGELAL 397 MF ++ + E V G FYVI +G +VL+ G D +E V +G SFGELAL Sbjct: 58 MFIEKFQSTEVVFHLDTIGTKFYVILDGQVEVLIRRRGFDELESVRILKKGE-SFGELAL 116 Query: 398 MYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKK 508 ++ PR A++R T +D+ F++IL KK Sbjct: 117 IHKQPRLATIRCVTDCTFAILDKQQFQKILHYEQTKK 153 Score = 32.7 bits (71), Expect = 5.1 Identities = 13/50 (26%), Positives = 27/50 (54%) Frame = +2 Query: 170 ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDV 319 I +F L+ Q+ + F E + V+++G+ D+F +++ G+F V Sbjct: 164 ISIFNQLNRTQLTSIYLNSFLYEYEKNQVVVQEGEKSDSFLIVKQGLFQV 213 >UniRef50_A1Z9N7 Cluster: CG8585-PE, isoform E; n=18; Pancrustacea|Rep: CG8585-PE, isoform E - Drosophila melanogaster (Fruit fly) Length = 1327 Score = 53.2 bits (122), Expect = 3e-06 Identities = 33/110 (30%), Positives = 57/110 (51%), Gaps = 1/110 (0%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340 V + F + D+ + V+ + + +PG+ +I++G G Y I+ GV D+++ + Sbjct: 1119 VASVPFFANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGE- 1177 Query: 341 VEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 V T GS FGE+ L+ N R ASVRA+T L+++ F +L Sbjct: 1178 ----VATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNCVL 1223 >UniRef50_UPI000038CAE8 Cluster: COG1252: NADH dehydrogenase, FAD-containing subunit; n=1; Nostoc punctiforme PCC 73102|Rep: COG1252: NADH dehydrogenase, FAD-containing subunit - Nostoc punctiforme PCC 73102 Length = 980 Score = 52.8 bits (121), Expect = 4e-06 Identities = 31/94 (32%), Positives = 51/94 (54%) Frame = +2 Query: 185 SLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTY 364 S+ Q+ Q + A F+ G+ +++QGD G Y+I NG +VL + E ++ T Sbjct: 421 SMKVQEKQSLKKAYFQA----GQVIVKQGDIGRCLYLIRNGEVEVLQEMSNG-ETIIQTI 475 Query: 365 EGSGSFGELALMYNMPRAASVRAQTAGALWAMDR 466 FGE +++ N P A+VRA+T+ L +DR Sbjct: 476 GSGEHFGETSVIENSPHIATVRAKTSVQLVVIDR 509 >UniRef50_A0DG99 Cluster: Chromosome undetermined scaffold_5, whole genome shotgun sequence; n=4; Oligohymenophorea|Rep: Chromosome undetermined scaffold_5, whole genome shotgun sequence - Paramecium tetraurelia Length = 869 Score = 52.8 bits (121), Expect = 4e-06 Identities = 33/111 (29%), Positives = 59/111 (53%), Gaps = 1/111 (0%) Frame = +2 Query: 146 RLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV 325 R + + I +F L + ++ +LD++ + PG+ VI++G GD FY+IE+G+ V Sbjct: 606 RRLDLLSTIDIFEHLTLKNVRWLLDSVTSEEFFPGQDVIKEGTAGDRFYIIESGL--ARV 663 Query: 326 TGDDRVEKVVHTYEGSGSFGELALMYNM-PRAASVRAQTAGALWAMDRHTF 475 + ++ Y+ FGE A++ N R ASV A T + +++H F Sbjct: 664 YSKQKGQEFERYYQVGDYFGESAVLSNEGRRGASVEAVTNLKVLILEKHDF 714 >UniRef50_Q3AAI0 Cluster: CBS/cyclic nucleotide-binding domain protein; n=1; Carboxydothermus hydrogenoformans Z-2901|Rep: CBS/cyclic nucleotide-binding domain protein - Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008) Length = 631 Score = 52.4 bits (120), Expect = 6e-06 Identities = 27/117 (23%), Positives = 58/117 (49%), Gaps = 1/117 (0%) Frame = +2 Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDN-FYVIENGVFDVLV 325 + + + I F L ++++ +++ + +PGEY+ R+ + N +++ NG+ +++V Sbjct: 1 MPQTLSHIYPFSLLPENLLEELSNSLTSRNYQPGEYIFREKEPARNGLFLVFNGILEIVV 60 Query: 326 TGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKS 496 T + + V+ FGE L P A +RA T + + ++ F IL K+ Sbjct: 61 TSERGQDLVIALRRPGEFFGETVLFSGEPYPAGIRAATEALIGFIPKNIFMEILNKN 117 >UniRef50_A7SE96 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 174 Score = 52.4 bits (120), Expect = 6e-06 Identities = 38/110 (34%), Positives = 56/110 (50%), Gaps = 6/110 (5%) Frame = +2 Query: 179 FRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG------VFDVLVTGDDR 340 F + QQ + + + E +IRQG +NFY I +G +F VTG+ R Sbjct: 51 FGEYPLKMQQQPVKVGWYESFEAKRVIIRQGHPAENFYFILSGTALVTLLFVDPVTGEQR 110 Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILL 490 V +GS SFGELAL+++ R+A+V + AL A+ R FR I + Sbjct: 111 SNTVAVLGKGS-SFGELALLHHKTRSATVLCKEDVALLAVGREDFRDIFM 159 >UniRef50_A0DXZ3 Cluster: Chromosome undetermined scaffold_69, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_69, whole genome shotgun sequence - Paramecium tetraurelia Length = 945 Score = 52.4 bits (120), Expect = 6e-06 Identities = 44/123 (35%), Positives = 62/123 (50%), Gaps = 10/123 (8%) Frame = +2 Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFE---KRSEPGEYVIRQGDDGDNFYVI---ENGV 310 L + V I F++L +Q VL M K + E + GD G FY+I GV Sbjct: 458 LLQLVEAIAFFKNLQSQNPDIVLRCMSVLSYKTVKKEEILFHVGDQGSLFYIILKGSVGV 517 Query: 311 FDVLVTGDD--RVE-KVVHTYEGSGSFGELALMY-NMPRAASVRAQTAGALWAMDRHTFR 478 F +L + DD R E K V+ + SFGELAL+ N R A++ A+ L M++H F+ Sbjct: 518 FILLPSPDDSKRFELKEVNILKAGNSFGELALLNDNAKRTATIIAKEDCMLAIMEKHHFK 577 Query: 479 RIL 487 IL Sbjct: 578 SIL 580 >UniRef50_P74608 Cluster: Slr1575 protein; n=1; Synechocystis sp. PCC 6803|Rep: Slr1575 protein - Synechocystis sp. (strain PCC 6803) Length = 479 Score = 52.0 bits (119), Expect = 8e-06 Identities = 29/113 (25%), Positives = 62/113 (54%) Frame = +2 Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 328 L++ ++ F L+ +++Q+++ + + E + R+ D D FY++ +G+ +V Sbjct: 314 LSQVLKSSDYFSGLNELEIRQLVEIGQLQSLQSEEVLFRERDPADGFYIVISGLVEVYT- 372 Query: 329 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 +++ +V+ + FGELALM +PR ASV+A+ L+ + F ++L Sbjct: 373 --EKLGRVLASLGPGSFFGELALMLGIPRTASVKAKEKSLLFVVRFPQFEQLL 423 >UniRef50_Q2ADG0 Cluster: Cyclic nucleotide-binding:Bacterial regulatory protein, Crp; n=1; Halothermothrix orenii H 168|Rep: Cyclic nucleotide-binding:Bacterial regulatory protein, Crp - Halothermothrix orenii H 168 Length = 219 Score = 52.0 bits (119), Expect = 8e-06 Identities = 28/113 (24%), Positives = 54/113 (47%) Frame = +2 Query: 164 RGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRV 343 R I LF L+ +Q+ + ++R + GE + +GD D FY++ G ++ D Sbjct: 7 RSIPLFSGLNDEQLDLLKSITNKRRYKAGEILFFEGDKPDAFYIVVEGEIQIIKVSYDGK 66 Query: 344 EKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAF 502 EK++ FGE+A++ + R+A+ R +L + F ++ + F Sbjct: 67 EKILEVMGPGDFFGEMAIIDSKGRSATARVIRDSSLLVVGNQEFLNLVREYPF 119 >UniRef50_Q7UTR3 Cluster: ATP-binding subunit of ABC transporter; n=1; Pirellula sp.|Rep: ATP-binding subunit of ABC transporter - Rhodopirellula baltica Length = 397 Score = 51.6 bits (118), Expect = 1e-05 Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 3/120 (2%) Frame = +2 Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316 + A L E + +F + + ++ +M PG+ ++ GD GD FY+I G Sbjct: 262 EAAVLGEMLSQCSVFSGVAISTLTELSRSMTRTTHGPGDRIVTYGDVGDRFYLIREGTVS 321 Query: 317 V---LVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 V G + +V EG+ FGE AL+ PR A V A T +++D TF ++ Sbjct: 322 VKQPTQPGGNDFREVAQLGEGA-YFGETALLTGEPRNAHVDATTETVTYSLDAPTFSDVM 380 >UniRef50_Q46TY3 Cluster: Cyclic nucleotide-binding; n=2; Cupriavidus necator|Rep: Cyclic nucleotide-binding - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 260 Score = 51.6 bits (118), Expect = 1e-05 Identities = 35/130 (26%), Positives = 52/130 (40%), Gaps = 2/130 (1%) Frame = +2 Query: 104 GAPAVFPKSDA--QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDD 277 G P P +A RA A ++ F L + +LD + GE + +GD Sbjct: 16 GIPRGTPGGNAAPSRAEAAATLQASAWFSQLPGPLREALLDDGTWRHLAAGEALFARGDA 75 Query: 278 GDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWA 457 D Y + +G V G+ ++ E FGE+ L +PR RA A LW Sbjct: 76 FDGLYCVASGTMQVDAAGESGKAALLGLLEAGAWFGEICLFDGLPRTHDARAVHAARLWH 135 Query: 458 MDRHTFRRIL 487 + R + R L Sbjct: 136 VPRASLERRL 145 >UniRef50_Q1D9I5 Cluster: PBS lyase HEAT-like repeat/cyclic nucleotide-binding domain protein; n=2; Cystobacterineae|Rep: PBS lyase HEAT-like repeat/cyclic nucleotide-binding domain protein - Myxococcus xanthus (strain DK 1622) Length = 1034 Score = 51.6 bits (118), Expect = 1e-05 Identities = 31/110 (28%), Positives = 49/110 (44%) Frame = +2 Query: 158 AVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDD 337 A+ G+ +F D + + E GE + QGD GD YVI +G D G+ Sbjct: 866 ALEGVSVFSQCDVDDIAAIAAVAREASFRTGERIYAQGDPGDALYVIVDGAVDAFHDGEH 925 Query: 338 RVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 V ++G +FGE++L+ PR + A + +DR F +L Sbjct: 926 -----VLRFQGKQAFGEVSLLDGAPRPTDMVAAVDTRVLIIDRRDFLDLL 970 >UniRef50_Q8ILS1 Cluster: Putative uncharacterized protein; n=1; Plasmodium falciparum 3D7|Rep: Putative uncharacterized protein - Plasmodium falciparum (isolate 3D7) Length = 838 Score = 51.6 bits (118), Expect = 1e-05 Identities = 31/110 (28%), Positives = 55/110 (50%), Gaps = 1/110 (0%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340 +R + + R L +++ Q+ AM + P +I+ D FY+I G+ V + Sbjct: 591 LRNVPILRYLSEEELVQISYAMKLEMYHPNHTIIKANTYDDKFYIICKGLVTVEKNTEGN 650 Query: 341 VEKVV-HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 +K+V + + FGELAL+ N+ R A+V T L ++ F+R+L Sbjct: 651 KDKIVLSNLKKTDYFGELALIKNIKRTANVILDTEAILLSLSDSEFKRLL 700 >UniRef50_Q7RDH4 Cluster: Reticulocyte-binding protein 2 homolog A, putative; n=7; Plasmodium (Vinckeia)|Rep: Reticulocyte-binding protein 2 homolog A, putative - Plasmodium yoelii yoelii Length = 1939 Score = 51.6 bits (118), Expect = 1e-05 Identities = 29/114 (25%), Positives = 58/114 (50%), Gaps = 1/114 (0%) Frame = +2 Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 328 + + ++ + + R L + + + +M + EP +I++GD D FY+I G+ V + Sbjct: 1737 ILQVLKNVPILRYLPLEILDNISYSMKIEIHEPNHTIIKEGDYDDKFYIICKGLATVDIP 1796 Query: 329 GDDRVEK-VVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 K ++ + + + FGEL+L+ N R A+V T L+++ F R+L Sbjct: 1797 SKFSYNKLIISSLKKADYFGELSLINNTARTANVVLDTTSILFSLVSSEFNRLL 1850 Score = 44.8 bits (101), Expect = 0.001 Identities = 23/87 (26%), Positives = 49/87 (56%), Gaps = 1/87 (1%) Frame = +2 Query: 251 EYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVR 430 +++IRQ DD +FY++++G ++ D V++T FGE+++++NM R +V Sbjct: 558 QFIIRQHDDPLDFYILKDGEVNIYYNNAD---NVINTLSAYSFFGEISIIFNMLRTCNVA 614 Query: 431 AQTAGAL-WAMDRHTFRRILLKSAFKK 508 ++ A+ +++ F +L K K+ Sbjct: 615 VKSDKAICYSISSEYFLSLLNKDIVKE 641 >UniRef50_UPI00006CA698 Cluster: cation channel family protein; n=2; Tetrahymena thermophila SB210|Rep: cation channel family protein - Tetrahymena thermophila SB210 Length = 2774 Score = 51.2 bits (117), Expect = 1e-05 Identities = 27/111 (24%), Positives = 59/111 (53%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340 V+ + +F A+ + ++L M+ + + ++V++ G+ +FY++ G +++ D+ Sbjct: 264 VQNVQIFNLGQAEFVAKMLKKMYPQVAVKDDFVLKMGESAQDFYILAKGRVEIV--NQDK 321 Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLK 493 ++V+ E FGE+A++ N R V+AQT + + F +IL K Sbjct: 322 -KQVIRVLEPGAYFGEVAILINQYRTCYVKAQTDCIFMCIKKDDFLKILNK 371 Score = 41.9 bits (94), Expect = 0.008 Identities = 26/89 (29%), Positives = 47/89 (52%), Gaps = 2/89 (2%) Frame = +2 Query: 248 GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMP--RAA 421 GE+V ++GD Y IE GV + V ++ E+V+ G FG L + +P R Sbjct: 828 GEFVFQKGDLAQEIYFIEEGVVQI-VNNNNNNEEVLAEISQYGYFGGLEFINIVPSLRKI 886 Query: 422 SVRAQTAGALWAMDRHTFRRILLKSAFKK 508 S++A+T +L+ ++ + ++L + F K Sbjct: 887 SIKAKTNTSLFMLELDQYYQLLEEYPFAK 915 >UniRef50_Q09BB3 Cluster: PKA regulatory subunit-like protein; n=1; Stigmatella aurantiaca DW4/3-1|Rep: PKA regulatory subunit-like protein - Stigmatella aurantiaca DW4/3-1 Length = 415 Score = 51.2 bits (117), Expect = 1e-05 Identities = 32/114 (28%), Positives = 56/114 (49%), Gaps = 1/114 (0%) Frame = +2 Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEP-GEYVIRQGDDGDNFYVIENGVFDVLV 325 L++ + LFR L +Q ++ + F+ S P G+ ++ QG D Y++ NG V++ Sbjct: 263 LSQTISTHALFRGLSREQ-KEAMTRDFQLCSVPVGKTLVEQGQPVDALYLLLNGHCQVVL 321 Query: 326 TGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 D + E FGE++++ N+P +VRA + L +DR R L Sbjct: 322 DEDTERASPLPALEEGDVFGEISMLLNVPATVTVRADSRCTLLRLDREACERHL 375 >UniRef50_A0YLS1 Cluster: Putative uncharacterized protein; n=1; Lyngbya sp. PCC 8106|Rep: Putative uncharacterized protein - Lyngbya sp. PCC 8106 Length = 486 Score = 51.2 bits (117), Expect = 1e-05 Identities = 25/122 (20%), Positives = 61/122 (50%) Frame = +2 Query: 122 PKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIE 301 P Q L + ++ ++ F + ++ +++ + + +++ +GD GD F++I Sbjct: 314 PVYSPQDLSLRDLLKKVVYFENFSNLEILSLIEKGYRQTYYSEQFIFHEGDPGDAFHIIL 373 Query: 302 NGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481 +G +++ ++ K + FGEL+L+ + R+A VRA+ ++ + R+ F+ Sbjct: 374 SGSVEIIA---EKANKHIRDLYAGDFFGELSLLMGIRRSAGVRAKEKTIVFVVSRNIFQN 430 Query: 482 IL 487 L Sbjct: 431 FL 432 >UniRef50_Q7K3Z6 Cluster: GH01501p; n=4; Diptera|Rep: GH01501p - Drosophila melanogaster (Fruit fly) Length = 861 Score = 51.2 bits (117), Expect = 1e-05 Identities = 29/89 (32%), Positives = 50/89 (56%), Gaps = 1/89 (1%) Frame = +2 Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403 +FE ++ G + QGD+G ++Y++ G DV++ G + V T + FG+LAL+ Sbjct: 224 VFEAHAQAGTILFNQGDEGRSWYILLKGSVDVVIHG----KGTVATLKTGDDFGKLALIN 279 Query: 404 NMPRAASVRAQTAGA-LWAMDRHTFRRIL 487 + PRAA++ + L +D+ F RIL Sbjct: 280 DAPRAATIVLKENNCHLLRVDKEHFNRIL 308 >UniRef50_Q23EB4 Cluster: ABC transporter family protein; n=3; Tetrahymena thermophila SB210|Rep: ABC transporter family protein - Tetrahymena thermophila SB210 Length = 2778 Score = 51.2 bits (117), Expect = 1e-05 Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 2/113 (1%) Frame = +2 Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV--T 328 + ++ +F Q + +++ M E PGE + ++GD D+ Y+I +G ++ + T Sbjct: 2226 KTIQKFKIFNCFHQQTINKIIFQMKEITVSPGEAIFQEGDLDDSIYLILSGQIEIFLKET 2285 Query: 329 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 D ++ T FGE+A PR AS R+ L ++R F +++ Sbjct: 2286 KRDSHSFILKTLSTDQIFGEIAFFSEQPRTASARSTCFSTLCKIERKDFIQVI 2338 >UniRef50_Q4WI41 Cluster: Cyclic nucleotide-binding domain protein; n=5; Eurotiomycetidae|Rep: Cyclic nucleotide-binding domain protein - Aspergillus fumigatus (Sartorya fumigata) Length = 900 Score = 51.2 bits (117), Expect = 1e-05 Identities = 31/113 (27%), Positives = 54/113 (47%) Frame = +2 Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 328 L + +R LF+S + +V + + S P +Y++ +GD+ Y + G V T Sbjct: 54 LIDRLRSFPLFQSTPESFLVEVAQHLRPQLSAPNDYILTEGDEAKAIYWLVRGA--VSAT 111 Query: 329 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 D E + E FGE+ ++ + PR A++ A+T L + + FR IL Sbjct: 112 SRDG-ESIYADLEPGAFFGEIGVLMDRPRTATIIARTRCLLVVLSKEDFRNIL 163 >UniRef50_A1CZ15 Cluster: Cyclic nucleotide-binding domain protein; n=22; Pezizomycotina|Rep: Cyclic nucleotide-binding domain protein - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 920 Score = 51.2 bits (117), Expect = 1e-05 Identities = 31/113 (27%), Positives = 54/113 (47%) Frame = +2 Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 328 L + +R LF+S + +V + + S P +Y++ +GD+ Y + G V T Sbjct: 54 LIDRLRSFPLFQSTPESFLVEVAQHLRPQLSAPNDYILTEGDEAKAIYWLVRGA--VSAT 111 Query: 329 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 D E + E FGE+ ++ + PR A++ A+T L + + FR IL Sbjct: 112 SRDG-ESIYADLEPGAFFGEIGVLMDRPRTATIIARTRCLLVVLSKEDFRNIL 163 >UniRef50_UPI000038CAE7 Cluster: COG1012: NAD-dependent aldehyde dehydrogenases; n=1; Nostoc punctiforme PCC 73102|Rep: COG1012: NAD-dependent aldehyde dehydrogenases - Nostoc punctiforme PCC 73102 Length = 639 Score = 50.8 bits (116), Expect = 2e-05 Identities = 25/79 (31%), Positives = 43/79 (54%), Gaps = 1/79 (1%) Frame = +2 Query: 206 QQVLDAMFEKRS-EPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF 382 Q VL+ + + S G Y+ ++G D+ Y++E G+ + + VV+ E F Sbjct: 20 QMVLEKIMQPVSFSAGTYIFKEGSFADSCYILEEGIVRIETASESSSNFVVNYLEAGTIF 79 Query: 383 GELALMYNMPRAASVRAQT 439 GE++L+ MPR+A+ AQT Sbjct: 80 GEISLLDKMPRSATAYAQT 98 >UniRef50_Q6MJQ6 Cluster: Hyperpolarization-activated, cyclic nucleotide-gated K+; n=1; Bdellovibrio bacteriovorus|Rep: Hyperpolarization-activated, cyclic nucleotide-gated K+ - Bdellovibrio bacteriovorus Length = 130 Score = 50.8 bits (116), Expect = 2e-05 Identities = 27/90 (30%), Positives = 52/90 (57%), Gaps = 1/90 (1%) Frame = +2 Query: 221 AMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKV-VHTYEGSGSFGELAL 397 A+ ++ +PG+++ +GD ++FY++E+GV + T D +++ + SFGE AL Sbjct: 6 AIVKETYKPGDFIFFEGDIENHFYIVESGVVSIF-TKDQMGKRIPICDIVDGESFGEFAL 64 Query: 398 MYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 + PR+AS +A T L + F+++L Sbjct: 65 ISKSPRSASAQAVTDVVLVKVSEEGFQQLL 94 >UniRef50_A3YU63 Cluster: Possible mechanosensitive ion channel; n=1; Synechococcus sp. WH 5701|Rep: Possible mechanosensitive ion channel - Synechococcus sp. WH 5701 Length = 492 Score = 50.8 bits (116), Expect = 2e-05 Identities = 30/107 (28%), Positives = 55/107 (51%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355 LF L ++M Q+ R PGE V+R+G+ GD+ + + G+ +VL ++ V Sbjct: 340 LFGDLSEEEMLQLARNTRCLRFAPGEVVVREGNRGDSLFQVVQGMVEVLKNQEEEEPFQV 399 Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKS 496 + FGE++++ R+A+VRA L + R + +LL++ Sbjct: 400 ACLKPGDVFGEMSMLAGSQRSATVRALDECLLLEVSRTSLGPLLLQN 446 >UniRef50_A3EYY6 Cluster: Tetrameric potassium-selective cyclic nucleotide gated channel; n=4; Eumetazoa|Rep: Tetrameric potassium-selective cyclic nucleotide gated channel - Strongylocentrotus purpuratus (Purple sea urchin) Length = 2238 Score = 50.8 bits (116), Expect = 2e-05 Identities = 32/107 (29%), Positives = 54/107 (50%), Gaps = 1/107 (0%) Frame = +2 Query: 170 ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL-VTGDDRVE 346 + LFR D ++ + + P + ++RQGD GD Y I GV + L V RV Sbjct: 2097 VALFREADEAFLRALSLMLKPVLFMPNDLIVRQGDVGDEMYFICRGVVEELEVNSHSRVA 2156 Query: 347 KVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 +V+ T E ++ L+Y++PR S RA+T + ++ H + +L Sbjct: 2157 RVLETGE---FLDDINLLYDVPRRTSYRARTHVDVLSLSVHDLKSVL 2200 Score = 47.6 bits (108), Expect = 2e-04 Identities = 24/79 (30%), Positives = 45/79 (56%) Frame = +2 Query: 251 EYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVR 430 EY++R+ D G + I G+ +V V+ D + V T + FGE++L+++ PR AS+R Sbjct: 1489 EYIVRKHDFGKEMFFIHRGLVEV-VSEDGSI--VFDTMQAGRFFGEISLVFSCPRTASIR 1545 Query: 431 AQTAGALWAMDRHTFRRIL 487 AQ ++ +++ +L Sbjct: 1546 AQNNVDMFVLNKEDLDEVL 1564 Score = 42.7 bits (96), Expect = 0.005 Identities = 31/112 (27%), Positives = 52/112 (46%), Gaps = 1/112 (0%) Frame = +2 Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334 E + + LF+ D+ ++ + + PG+ ++ QGD G Y I G +VL Sbjct: 908 ETLSKVPLFKECDSNFLRMLALKLHVFIFMPGDVIVYQGDMGREMYFIRRGTCEVLSKDG 967 Query: 335 DRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 + V + G G FGE+ L++ R A+VRA + L + R R+L Sbjct: 968 NHVMSNI----GPGQYFGEVGLIFGDYRTATVRAASYCELLMLKRVDLDRVL 1015 Score = 39.5 bits (88), Expect = 0.045 Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 5/94 (5%) Frame = +2 Query: 224 MFEKRSEPGEYVIRQGDDGDN-----FYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGE 388 M +P Y+ RQ G N Y I+ G +VL DD + G FGE Sbjct: 381 MLSLEIKPSLYLPRQKIAGRNEICHDMYFIQRGEIEVLSADDDDTP-IARLNHGK-LFGE 438 Query: 389 LALMYNMPRAASVRAQTAGALWAMDRHTFRRILL 490 ++L+++MPR ++RA L +D+ + +LL Sbjct: 439 VSLIFSMPRTNTIRAAAHCDLLVLDKGDLQNVLL 472 >UniRef50_Q10898 Cluster: Uncharacterized protein Rv0104/MT0113; n=8; Mycobacterium tuberculosis complex|Rep: Uncharacterized protein Rv0104/MT0113 - Mycobacterium tuberculosis Length = 504 Score = 50.8 bits (116), Expect = 2e-05 Identities = 29/76 (38%), Positives = 39/76 (51%) Frame = +2 Query: 248 GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASV 427 G + RQG+ D+F+VIE+G + LV G KV+ FGE L+ M R A+V Sbjct: 401 GYTLFRQGERADHFFVIESGELEALVDG-----KVILRLGAGDHFGEACLLGGMRRIATV 455 Query: 428 RAQTAGALWAMDRHTF 475 RA LW +D F Sbjct: 456 RACEPSVLWELDGKAF 471 >UniRef50_UPI00006D001F Cluster: cyclic nucleotide-binding domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 705 Score = 50.4 bits (115), Expect = 2e-05 Identities = 27/109 (24%), Positives = 56/109 (51%), Gaps = 2/109 (1%) Frame = +2 Query: 173 LLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGD-NFYVIENGVFDVLVTG-DDRVE 346 L + + +++++ M E P E + +Q + D + Y I++G+ ++ V+ ++ E Sbjct: 120 LFIANFSQKVIKEIIFLMEEIIVAPNEIIFKQCEAEDQSIYFIQSGLVEIFVSNTQEQSE 179 Query: 347 KVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLK 493 KV+ E FGE++ +PR AS R+ ++ ++R F +L K Sbjct: 180 KVITQLEQDSMFGEISFFSGLPRTASARSLKLSTIYQINREKFLNLLKK 228 >UniRef50_Q131K0 Cluster: Cyclic nucleotide-binding precursor; n=1; Rhodopseudomonas palustris BisB5|Rep: Cyclic nucleotide-binding precursor - Rhodopseudomonas palustris (strain BisB5) Length = 367 Score = 50.4 bits (115), Expect = 2e-05 Identities = 36/113 (31%), Positives = 54/113 (47%) Frame = +2 Query: 146 RLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV 325 R E V + FR L A + ++ + + G V+R+G+ GD Y I +G V V Sbjct: 235 RTWELVISVPFFRDLGAAAVADIVRLLQARDVNAGTVVVREGEPGDAMYFIVSGEATVRV 294 Query: 326 TGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484 K V GS FGE+AL++N PR+A+V A L +D F ++ Sbjct: 295 A-----PKPVVLGPGS-FFGEMALLFNTPRSATVVATQPSVLLVLDIADFHQL 341 >UniRef50_Q5CD46 Cluster: PKA regulatory subunit homologous protein; n=6; Myxococcales|Rep: PKA regulatory subunit homologous protein - Myxococcus xanthus Length = 405 Score = 50.4 bits (115), Expect = 2e-05 Identities = 38/119 (31%), Positives = 56/119 (47%), Gaps = 2/119 (1%) Frame = +2 Query: 140 RARLAE-AVRGILLFRSLDAQQMQQVLDAMFEKRS-EPGEYVIRQGDDGDNFYVIENGVF 313 R R+ E +R LF L Q V FE RS GE ++ QG GD FYV+ G Sbjct: 251 RRRMVENLLRSNPLFNQLSPAQKAAV-SRDFELRSFAAGEALMTQGQPGDAFYVLLRGRC 309 Query: 314 DVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILL 490 + + FGE++L+ + P +A+VRA AG + ++R F++ LL Sbjct: 310 TPWLEQPHGRRVALSALREGDVFGEISLLLDKPVSATVRADVAGVVLRLERDAFQKHLL 368 Score = 48.0 bits (109), Expect = 1e-04 Identities = 31/113 (27%), Positives = 53/113 (46%), Gaps = 1/113 (0%) Frame = +2 Query: 131 DAQRARLAE-AVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG 307 +A RA +AE G+ + + + +L+ + + PG+ V+ +G G + + + G Sbjct: 117 EATRAHVAEDGATGLPILSQVSRETFVALLEVLQVRAFFPGQTVVEEGTPGASMFALVEG 176 Query: 308 VFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDR 466 DV+ +D + V T FGELAL+ PR A+V A L + R Sbjct: 177 RADVVRALEDGQRRSVGTVTPGDFFGELALISEGPRLATVVATERAVLLELTR 229 >UniRef50_A6G0I3 Cluster: Putative uncharacterized protein; n=1; Plesiocystis pacifica SIR-1|Rep: Putative uncharacterized protein - Plesiocystis pacifica SIR-1 Length = 428 Score = 50.4 bits (115), Expect = 2e-05 Identities = 27/80 (33%), Positives = 42/80 (52%) Frame = +2 Query: 242 EPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAA 421 EPGE +I++G+ + YVI +G +V GDD E+ + + FGE A+ + R A Sbjct: 326 EPGEVIIQEGEVAETAYVIIDGSCEVSRVGDDGGEQRLRVMDAGEVFGETAIFAGVRRTA 385 Query: 422 SVRAQTAGALWAMDRHTFRR 481 +VRA + + R F R Sbjct: 386 TVRALEPTKVGVITRDLFER 405 >UniRef50_UPI00006CA699 Cluster: cyclic nucleotide-binding domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 2731 Score = 50.0 bits (114), Expect = 3e-05 Identities = 32/112 (28%), Positives = 58/112 (51%), Gaps = 1/112 (0%) Frame = +2 Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334 E + + +F Q + +++ + K + +Y+I+ G+ + FY+I G ++L G Sbjct: 232 ELISNVQIFNLGSPQFVLKMIKKLHPKVAVKDDYIIKIGEIAEEFYIISKGKVEML--GG 289 Query: 335 DRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 D+ K V+ SGS FGE+ ++ N R VRAQT L + + F ++L Sbjct: 290 DK--KTVNRILESGSYFGEVGILLNQYRTCYVRAQTDCILMCIKKEDFLQLL 339 Score = 48.8 bits (111), Expect = 7e-05 Identities = 30/97 (30%), Positives = 49/97 (50%), Gaps = 3/97 (3%) Frame = +2 Query: 227 FEKRSEP-GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403 FEK P GE+V ++GD Y IE G+ ++ DD E+++ + FG L + Sbjct: 692 FEKILVPRGEFVFQKGDLAQEMYFIEEGIIQIVKFNDDLKEEILGEIYKNSYFGGLEFIN 751 Query: 404 NMP--RAASVRAQTAGALWAMDRHTFRRILLKSAFKK 508 +P R SVRA+T L+ + ++ I+ + F K Sbjct: 752 KVPTLRKVSVRAKTNACLYMLKMQSYIDIVQEYPFCK 788 >UniRef50_UPI000065D7C1 Cluster: Homolog of Oncorhynchus mykiss "Hyperpolarization-activated cyclic nucleotide-gated cation channel 1.; n=1; Takifugu rubripes|Rep: Homolog of Oncorhynchus mykiss "Hyperpolarization-activated cyclic nucleotide-gated cation channel 1. - Takifugu rubripes Length = 783 Score = 50.0 bits (114), Expect = 3e-05 Identities = 30/117 (25%), Positives = 60/117 (51%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340 V + LF + D + +L + + +P +Y++R+G G + I++GV +L G+ Sbjct: 391 VASMPLFANADPNFVTAMLTKLRFEVFQPKDYIVREGTIGKKMFFIQHGVVSILTKGNIS 450 Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511 ++ + +Y FGE+ L+ R ASV+A+T L+++ F +L + +R Sbjct: 451 MKLMDGSY-----FGEICLLTRGRRTASVQAETYCRLYSLSVDNFNEVLEEYPMMRR 502 >UniRef50_Q98GM7 Cluster: Mlr3256 protein; n=2; Alphaproteobacteria|Rep: Mlr3256 protein - Rhizobium loti (Mesorhizobium loti) Length = 151 Score = 50.0 bits (114), Expect = 3e-05 Identities = 29/80 (36%), Positives = 43/80 (53%) Frame = +2 Query: 248 GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASV 427 G+ + RQGD+GD YVI +G D+LV D KV S GE+A++ N R A+V Sbjct: 39 GQILFRQGDEGDAAYVILSGKADILVESDSGPIKVAELVPNS-IVGEIAILCNSSRTATV 97 Query: 428 RAQTAGALWAMDRHTFRRIL 487 RA + + + F R++ Sbjct: 98 RAASPLEALRIPKDHFLRLM 117 >UniRef50_Q2LPZ1 Cluster: Cyclic nucleotide-binding domain protein; n=1; Syntrophus aciditrophicus SB|Rep: Cyclic nucleotide-binding domain protein - Syntrophus aciditrophicus (strain SB) Length = 229 Score = 50.0 bits (114), Expect = 3e-05 Identities = 28/114 (24%), Positives = 50/114 (43%) Frame = +2 Query: 146 RLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV 325 ++ E + I LF L QQ+ ++ ++ + G+ + +GD+G FY++ +G V Sbjct: 3 KVLEIIGSIPLFNGLSEQQLGEIRGIARDRFYDKGKEIFAEGDEGGGFYIVASGQVKVFK 62 Query: 326 TGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 + E ++H Y SFGE+ + AS L R F +L Sbjct: 63 LSPEGKEHILHIYGPGHSFGEVPVFSGERFPASAETLLKSHLLFFPRTDFVALL 116 >UniRef50_Q1D5Q4 Cluster: Cyclic nucleotide-binding domain protein; n=1; Myxococcus xanthus DK 1622|Rep: Cyclic nucleotide-binding domain protein - Myxococcus xanthus (strain DK 1622) Length = 715 Score = 50.0 bits (114), Expect = 3e-05 Identities = 32/93 (34%), Positives = 46/93 (49%) Frame = +2 Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334 +A+ I LF L ++ + +R P E +I QG GD FYVI G V T + Sbjct: 442 DALPTIPLFSDLPRDAFIELFERCPLRRFGPDERIIDQGSHGDAFYVICEGAVRVFRTEE 501 Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 433 + + + T EG FGE+AL+ R ASV + Sbjct: 502 GQRQDIA-TLEGGTFFGEMALLSGAARTASVES 533 Score = 37.1 bits (82), Expect = 0.24 Identities = 27/104 (25%), Positives = 45/104 (43%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355 LFR + + +++ + E +IR GD D YV+ +G +V G + Sbjct: 580 LFRLFGRKDRRALVERFRSRDVERDTVIIRDGDPTDGLYVVLSGEVEVRKDG----HLLT 635 Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 EG FGE++L+ P A+V A L + R F ++ Sbjct: 636 QLREGD-VFGEISLLQKTPATATVTATRHTTLLRLPRADFDALI 678 >UniRef50_Q08NQ8 Cluster: Protein phosphatase 1; n=2; Cystobacterineae|Rep: Protein phosphatase 1 - Stigmatella aurantiaca DW4/3-1 Length = 470 Score = 49.6 bits (113), Expect = 4e-05 Identities = 36/111 (32%), Positives = 56/111 (50%) Frame = +2 Query: 101 EGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDG 280 +GA A S+AQ +R+ EA+R I LFR L ++ VL + G ++ +G G Sbjct: 301 DGAVASEETSEAQ-SRM-EALRKIPLFRHLTYKEQTAVLSIATTRTFPAGREIVVEGQPG 358 Query: 281 DNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 433 + +V+ G + G + E G FGE+ L+ N PR+A+VRA Sbjct: 359 EELFVVIRGRVVIEKNGVEIAE-----LRAGGHFGEMGLIDNAPRSATVRA 404 >UniRef50_A0YM45 Cluster: Sulfate transporter family protein; n=1; Lyngbya sp. PCC 8106|Rep: Sulfate transporter family protein - Lyngbya sp. PCC 8106 Length = 759 Score = 49.6 bits (113), Expect = 4e-05 Identities = 27/98 (27%), Positives = 44/98 (44%) Frame = +2 Query: 191 DAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEG 370 D+QQ+ ++ + + P E++ R GD D Y +E G V+ K V TY Sbjct: 627 DSQQVIMLMKYLKLLQISPDEFIFRTGDLADGLYFVETGQVSVIFELPTGQMKRVQTYYS 686 Query: 371 SGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484 GE+ N+PR AS+ A L+ + F ++ Sbjct: 687 GTILGEIGHYMNVPRTASIIADQPSRLYYLSTQAFEQM 724 >UniRef50_Q23WN2 Cluster: Cyclic nucleotide-binding domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 1010 Score = 49.6 bits (113), Expect = 4e-05 Identities = 26/69 (37%), Positives = 39/69 (56%) Frame = +2 Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403 M +R G+ V QGD G FY+I G+ + + + +KV G SFGELAL+ Sbjct: 61 MTYERFNSGDMVFSQGDRGSKFYIILEGLVGIYIKIKNEQKKVKELSRGE-SFGELALIN 119 Query: 404 NMPRAASVR 430 + PR+AS++ Sbjct: 120 DAPRSASIK 128 >UniRef50_P63401 Cluster: Uncharacterized ABC transporter ATP-binding protein Rv2564/MT2640; n=14; Mycobacterium tuberculosis complex|Rep: Uncharacterized ABC transporter ATP-binding protein Rv2564/MT2640 - Mycobacterium tuberculosis Length = 330 Score = 49.6 bits (113), Expect = 4e-05 Identities = 25/80 (31%), Positives = 42/80 (52%) Frame = +2 Query: 248 GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASV 427 GE + Q GD YV+ G F+++ D E++V T FGE+ +++++PR+A+V Sbjct: 234 GEVLFEQSTMGDLIYVVSEGEFEIVRELADGGEELVKTAAPGDYFGEIGVLFHLPRSATV 293 Query: 428 RAQTAGALWAMDRHTFRRIL 487 RA++ FR L Sbjct: 294 RARSDATAVGYTAQAFRERL 313 >UniRef50_UPI00006CC0E9 Cluster: cation channel family protein; n=1; Tetrahymena thermophila SB210|Rep: cation channel family protein - Tetrahymena thermophila SB210 Length = 1238 Score = 49.2 bits (112), Expect = 6e-05 Identities = 27/100 (27%), Positives = 51/100 (51%), Gaps = 5/100 (5%) Frame = +2 Query: 203 MQQVLDAMFEKRSEPGEYVIRQGDDGD-NFYVIENGVFDVLVT----GDDRVEKVVHTYE 367 +++ + + EKR P E + RQ D GD N Y I +G + + G ++ +++ + + Sbjct: 496 LERTVSIIKEKRYYPEEIIFRQNDTGDSNIYFIASGQVQIYIEASYPGGEKKVQILQSLQ 555 Query: 368 GSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 SFG + PR +VR Q L +++R++F +L Sbjct: 556 SGQSFGHYSFFTGQPRMVNVRTQGFVTLLSINRNSFINLL 595 >UniRef50_Q2YZI3 Cluster: Putative uncharacterized protein; n=1; uncultured gamma proteobacterium|Rep: Putative uncharacterized protein - uncultured gamma proteobacterium Length = 354 Score = 49.2 bits (112), Expect = 6e-05 Identities = 30/111 (27%), Positives = 57/111 (51%), Gaps = 1/111 (0%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL-VTGDDRVEKV 352 +F+ + +Q + M + GE VIRQG++G++FY+I +G V+ T + V Sbjct: 149 VFQRIPPGNIQSIFIRMQTHHFKAGEAVIRQGEEGEHFYIIRDGHCRVIRKTRKNPEGMV 208 Query: 353 VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFK 505 + + +FGE +L+ R AS+ ++ G L ++ + F +L + K Sbjct: 209 LARLKAGDNFGEESLISGGKRNASIVMESDGVLMSLSKTDFLELLNEPLLK 259 >UniRef50_Q1PUQ2 Cluster: Similar to transcriptional regulator of Crp/Fnr family; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Similar to transcriptional regulator of Crp/Fnr family - Candidatus Kuenenia stuttgartiensis Length = 228 Score = 49.2 bits (112), Expect = 6e-05 Identities = 27/109 (24%), Positives = 51/109 (46%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340 ++ + LF SL +Q++ + A K + Q D GD FY++ G + + +D Sbjct: 10 LKNVPLFNSLANEQLKTLFRAGITKSFPKDHVIFYQHDHGDTFYIVITGKVKITLLNEDG 69 Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 E V+ + FGE++LM + R+ S L+ R+ F +++ Sbjct: 70 KEIVLSLLKEGDFFGEMSLMDDETRSVSAVCVENTTLFLFTRNQFHKLI 118 >UniRef50_A4M043 Cluster: Transcriptional regulator, Crp/Fnr family; n=1; Geobacter bemidjiensis Bem|Rep: Transcriptional regulator, Crp/Fnr family - Geobacter bemidjiensis Bem Length = 238 Score = 49.2 bits (112), Expect = 6e-05 Identities = 28/110 (25%), Positives = 51/110 (46%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340 +R I LF LD + +V + EKR + V+ + D + Y++ G V+ G + Sbjct: 18 LRAIPLFSCLDPLEFSEVQRRIMEKRFHKNQVVLLEEDTANYMYIVYGGKVRVVHLGSEG 77 Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILL 490 E+++ ++ FGE+AL+ A+V A + + + TF L Sbjct: 78 SERILAVHKRGDVFGEMALLDAKTAPATVIAMEDAEIGLLSKETFDTFFL 127 >UniRef50_Q4D6P2 Cluster: Regulatory subunit of protein kinase a-like protein, putative; n=2; Trypanosoma cruzi|Rep: Regulatory subunit of protein kinase a-like protein, putative - Trypanosoma cruzi Length = 558 Score = 49.2 bits (112), Expect = 6e-05 Identities = 36/155 (23%), Positives = 70/155 (45%) Frame = +2 Query: 50 RKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMF 229 R + A + EE S E A KS + + + + LF LD +++ ++ M Sbjct: 237 RLGISARSIGAEEMMSTEFPTAA--KSSEAASFIMKVLEKHFLFSFLDDKELHKLAMVMN 294 Query: 230 EKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNM 409 + G V+ +G+ FY+I +G + + DD + + FGEL L+Y Sbjct: 295 TEDFPEGIKVLVKGETNSKFYIILDGSATITMFEDDPDRIETESLQKGSVFGELGLLYET 354 Query: 410 PRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 SV + T ++R+T++ ++ ++ +KR+ Sbjct: 355 QSEVSVESTTPLFCATLERNTYKIVVSRAEEEKRQ 389 Score = 47.2 bits (107), Expect = 2e-04 Identities = 30/120 (25%), Positives = 56/120 (46%), Gaps = 1/120 (0%) Frame = +2 Query: 131 DAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGV 310 + +R R + + L AQ+ ++ +A+ E + G+ +IR G+ D ++I G Sbjct: 385 EEKRQRYFSFLENAPFIKDLPAQERLKIAEALKEDKYTEGDKIIRYGEKVDWLHIIVEGT 444 Query: 311 FDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWA-MDRHTFRRIL 487 DV+ ++ E+ V T FG+L +Y+ A V A + A M R F +++ Sbjct: 445 ADVIGRNEEGEEEYVVTKNAGECFGDLEFLYHHETVADVVATSPFVRTAKMSRLHFEQLI 504 >UniRef50_Q22R60 Cluster: Cyclic nucleotide-binding domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 863 Score = 49.2 bits (112), Expect = 6e-05 Identities = 26/77 (33%), Positives = 42/77 (54%) Frame = +2 Query: 257 VIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQ 436 VI G+ GD FY+I G+ ++ V V + SFGELAL+ + PR A+++AQ Sbjct: 86 VIVHGERGDKFYIILQGICEIYVPNSQGQFVKVGELKAGQSFGELALINDSPRRATIKAQ 145 Query: 437 TAGALWAMDRHTFRRIL 487 T L + + + +I+ Sbjct: 146 TDCDLAILSKKDYIKII 162 >UniRef50_Q8WZA2 Cluster: Rap guanine nucleotide exchange factor 4; n=53; Coelomata|Rep: Rap guanine nucleotide exchange factor 4 - Homo sapiens (Human) Length = 1011 Score = 49.2 bits (112), Expect = 6e-05 Identities = 29/89 (32%), Positives = 49/89 (55%), Gaps = 1/89 (1%) Frame = +2 Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403 +FE ++ G + QG++G ++Y+I G +V++ G + VV T FG+LAL+ Sbjct: 373 IFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYG----KGVVCTLHEGDDFGKLALVN 428 Query: 404 NMPRAASVRAQTAGA-LWAMDRHTFRRIL 487 + PRAAS+ + +D+ F RIL Sbjct: 429 DAPRAASIVLREDNCHFLRVDKEDFNRIL 457 Score = 38.7 bits (86), Expect = 0.078 Identities = 26/110 (23%), Positives = 51/110 (46%), Gaps = 2/110 (1%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV--TGD 334 ++ + F + Q+ + + E G + RQGD G N+Y + G DV V T Sbjct: 38 LKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSS 97 Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484 + + T +FGE +++ N PR A++ + + L +++ F+ + Sbjct: 98 HQDAVTICTLGIGTAFGE-SILDNTPRHATIVTRESSELLRIEQKDFKAL 146 >UniRef50_Q9P1Z3 Cluster: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3; n=61; Eukaryota|Rep: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 - Homo sapiens (Human) Length = 774 Score = 49.2 bits (112), Expect = 6e-05 Identities = 34/112 (30%), Positives = 54/112 (48%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355 LF D + VL + + +PG+ V+R+G G Y I++G+ VL G + Sbjct: 428 LFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLARG----ARDT 483 Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511 +GS FGE+ L+ R ASVRA T L+++ F +L + +R Sbjct: 484 RLTDGS-YFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRR 534 >UniRef50_Q1GWA6 Cluster: Cyclic nucleotide-binding protein precursor; n=4; Sphingomonadales|Rep: Cyclic nucleotide-binding protein precursor - Sphingopyxis alaskensis (Sphingomonas alaskensis) Length = 811 Score = 48.8 bits (111), Expect = 7e-05 Identities = 30/101 (29%), Positives = 56/101 (55%), Gaps = 1/101 (0%) Frame = +2 Query: 188 LDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYE 367 L A+ + V++A +R G+ V+ +G+ GD+ YVI +G ++V D + + Y Sbjct: 478 LTAEDLAPVVEAAEVERVPAGKAVLIEGEQGDDVYVIRSG--SMVVEKDIGGKPIFLRYL 535 Query: 368 GSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 +GS FGE+ ++ PR A+V+A + + +FR++L Sbjct: 536 PAGSFFGEMGVLSGEPRNATVKAAVGSEVIKLTGDSFRKML 576 >UniRef50_Q0VMY3 Cluster: CAMP-dependent protein kinase regulatory chain; n=1; Alcanivorax borkumensis SK2|Rep: CAMP-dependent protein kinase regulatory chain - Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) Length = 355 Score = 48.8 bits (111), Expect = 7e-05 Identities = 32/127 (25%), Positives = 57/127 (44%) Frame = +2 Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 304 + DA +A+ LF ++ + + E+ + GE ++++GD GD +VI+ Sbjct: 127 EDDANERDWMDALLSSELFSAVPPAMIHSLFVKFQEREVQLGEVIVKEGDHGDTLFVIKQ 186 Query: 305 GVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484 G V + E + G FGE AL+ PR A++ + G L + + F+ I Sbjct: 187 GKAMVTRIKGAKQETLAALSAGR-FFGEDALISESPRNATITMTSDGVLMCLGKSDFQAI 245 Query: 485 LLKSAFK 505 L S + Sbjct: 246 LQDSVIR 252 >UniRef50_A0YHV0 Cluster: Putative uncharacterized protein; n=1; marine gamma proteobacterium HTCC2143|Rep: Putative uncharacterized protein - marine gamma proteobacterium HTCC2143 Length = 159 Score = 48.8 bits (111), Expect = 7e-05 Identities = 23/64 (35%), Positives = 39/64 (60%) Frame = +2 Query: 248 GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASV 427 GE+ Q D GD+ +++E G ++ T + ++ V+ T FGE+AL+ PR+A+V Sbjct: 39 GEFFFHQNDKGDSLFLLEKGSAEIFKTFNG-IDYVLRTVNNGDCFGEMALIDFTPRSATV 97 Query: 428 RAQT 439 RA+T Sbjct: 98 RAKT 101 >UniRef50_Q00X68 Cluster: Cyclic nucleotide dependent protein kinase; n=3; Eukaryota|Rep: Cyclic nucleotide dependent protein kinase - Ostreococcus tauri Length = 1179 Score = 48.8 bits (111), Expect = 7e-05 Identities = 36/128 (28%), Positives = 62/128 (48%), Gaps = 5/128 (3%) Frame = +2 Query: 137 QRARLAEAVRGILLFR-SLDAQQMQQVLDAMFEKRSEPGEYVIRQGD----DGDNFYVIE 301 +R RL + + +FR SLDA+ M ++DA+ E E G ++ D + FYV+ Sbjct: 197 RRCRLTSYLDAVEVFRESLDARTMSMLVDALREVTFESGHVIVSPDDVYEEESSKFYVVI 256 Query: 302 NGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481 +G + +V DD + V+ FGEL+L++ A V A + +D +F R Sbjct: 257 DG--EAVVYVDDGSKAEVNRLRRGDYFGELSLIHKTSPTAMVIAVGQVSALTLDAESFYR 314 Query: 482 ILLKSAFK 505 ++ + K Sbjct: 315 MIGEKTVK 322 Score = 43.6 bits (98), Expect = 0.003 Identities = 21/51 (41%), Positives = 35/51 (68%), Gaps = 1/51 (1%) Frame = +2 Query: 362 YEGSGSFGELALMYNMPRAASVRAQTAGA-LWAMDRHTFRRILLKSAFKKR 511 Y G +FGE+AL+ PR A+V A+++ LWA+DR TF+ + ++ F++R Sbjct: 149 YPGD-TFGEVALVRKCPRTATVIAESSSVKLWALDRATFQETVKRTTFERR 198 Score = 39.9 bits (89), Expect = 0.034 Identities = 21/74 (28%), Positives = 39/74 (52%), Gaps = 1/74 (1%) Frame = +2 Query: 89 DDSDEGAPA-VFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIR 265 DD+DE A + ++ +EA+ G+ LFR L + ++ E E G+ ++R Sbjct: 17 DDADENARIRARARRVSEPESASEALDGVALFRELKRDARAALCGSVVECEYERGDVIVR 76 Query: 266 QGDDGDNFYVIENG 307 + + G +FYV+ +G Sbjct: 77 KNEVGTHFYVVAHG 90 >UniRef50_A4RUE3 Cluster: Predicted protein; n=1; Ostreococcus lucimarinus CCE9901|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 121 Score = 48.8 bits (111), Expect = 7e-05 Identities = 36/120 (30%), Positives = 56/120 (46%), Gaps = 10/120 (8%) Frame = +2 Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG-VF 313 +R R + I +F L + + V+ +PGE +IRQG+ D FYVI G Sbjct: 1 RRLRYERTLAKIPVFADLGSYERAMVVKQAKRFSFKPGEKIIRQGEVADKFYVILKGSAV 60 Query: 314 DVLVTGD-DRV--------EKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDR 466 GD D V ++++ + FGELAL+ PR A++ A + + A+DR Sbjct: 61 STKSDGDVDHVAPGSKIPPDRIMRNFSQGQYFGELALLTGQPRLATIVANDSLEVLAIDR 120 >UniRef50_Q23EB1 Cluster: Cation channel family protein; n=2; Tetrahymena thermophila SB210|Rep: Cation channel family protein - Tetrahymena thermophila SB210 Length = 1130 Score = 48.8 bits (111), Expect = 7e-05 Identities = 27/106 (25%), Positives = 50/106 (47%), Gaps = 2/106 (1%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKV- 352 +F Q + +++ M E PGE + +GD D+ Y+I +G +L + + Sbjct: 609 IFNCFSQQSINKLVFQMKEIIVSPGEVIFSEGDRDDSIYLITSGQIQILQNTAQKSCSIF 668 Query: 353 -VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 + T + FGE+A MPR A+ ++ L+ ++R F I+ Sbjct: 669 QLKTLSENQIFGEIAFFSQMPRTATAKSLNLSTLYKIERKDFIEIV 714 >UniRef50_UPI00006CF9CA Cluster: cation channel family protein; n=1; Tetrahymena thermophila SB210|Rep: cation channel family protein - Tetrahymena thermophila SB210 Length = 1108 Score = 48.4 bits (110), Expect = 1e-04 Identities = 35/118 (29%), Positives = 61/118 (51%), Gaps = 6/118 (5%) Frame = +2 Query: 176 LFRSLDAQQ-MQQVLDAMFEKRSEPGEYVIRQ----GDDGDNFYVIENGVFDVLVTGDDR 340 LF + +Q + Q+ + EK + P E +I Q GDD + Y I++G ++ + Sbjct: 523 LFNQQNMEQFLFQISINLLEKITIPEEIIINQEESGGDDDQSMYFIQDGEVEIFYQHSN- 581 Query: 341 VEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511 K + G+GS FGE++ N+ R ASV++ +L+ + R F +IL K +K+ Sbjct: 582 -SKTILKKLGAGSYFGEISFFTNLQRTASVQSVNFASLYYLKRSEFIKILQKFPNQKK 638 >UniRef50_UPI00006A1C4D Cluster: Uncharacterized protein C20orf152.; n=2; Xenopus tropicalis|Rep: Uncharacterized protein C20orf152. - Xenopus tropicalis Length = 436 Score = 48.4 bits (110), Expect = 1e-04 Identities = 32/107 (29%), Positives = 55/107 (51%), Gaps = 4/107 (3%) Frame = +2 Query: 167 GILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL--VTGDDR 340 GIL FR +Q + ++ +R G ++R+G GD+FY + +GV V V G Sbjct: 30 GILSFRRYSSQMQLMLARVVYYRRFGRGRVIVRKGHRGDSFYFVFSGVIAVTQDVDGSSA 89 Query: 341 V--EKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTF 475 + + + ++G+ SFGE+AL+ ++ R A+V +DR F Sbjct: 90 LLDPEPILLHKGA-SFGEVALLKDLRRNATVVCMEETEFLVVDRMEF 135 >UniRef50_UPI0000EC9E1A Cluster: Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP).; n=1; Gallus gallus|Rep: Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP). - Gallus gallus Length = 766 Score = 48.4 bits (110), Expect = 1e-04 Identities = 29/89 (32%), Positives = 45/89 (50%), Gaps = 1/89 (1%) Frame = +2 Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403 MFE G + QGD G ++Y++ G +V+ G + +V T FG+LAL+ Sbjct: 189 MFESHQRAGTVLFSQGDKGTSWYIVWKGSVNVVTHG----KGLVATLHEGDDFGQLALVN 244 Query: 404 NMPRAASVRAQTAGA-LWAMDRHTFRRIL 487 + PRAAS+ + +D+ F RIL Sbjct: 245 DAPRAASIILREDNCHFLRVDKQDFNRIL 273 >UniRef50_Q1DAY2 Cluster: Cyclic nucleotide-binding domain protein; n=2; Cystobacterineae|Rep: Cyclic nucleotide-binding domain protein - Myxococcus xanthus (strain DK 1622) Length = 152 Score = 48.4 bits (110), Expect = 1e-04 Identities = 25/112 (22%), Positives = 53/112 (47%) Frame = +2 Query: 152 AEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTG 331 A ++ + LF L Q+ +V + G ++ R+G+ G +VI G + + Sbjct: 3 AAVLKKVALFEGLTQGQLAKVAQIGHSRTYPAGAFLFREGETGQEMFVIAEGKVRISKSV 62 Query: 332 DDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 E+ + E FGE+A++ + PR+A A + ++W ++R +++ Sbjct: 63 PGIGEEALAILEPGQYFGEMAVIEDSPRSADAIAHVSCSVWVIERSRLDQLM 114 >UniRef50_A6G5Y4 Cluster: Protein phosphatase/cyclic nucleotide-binding domain protein; n=1; Plesiocystis pacifica SIR-1|Rep: Protein phosphatase/cyclic nucleotide-binding domain protein - Plesiocystis pacifica SIR-1 Length = 433 Score = 48.4 bits (110), Expect = 1e-04 Identities = 34/127 (26%), Positives = 58/127 (45%), Gaps = 3/127 (2%) Frame = +2 Query: 116 VFPKSDAQRARLA---EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDN 286 V P D +R ++ + +R I LF L+ ++ ++ + GE ++R+GD+ D Sbjct: 262 VRPADDQRRRQVVNNLQTLRHIALFMDLNDSELVRIFRRFQARDYGQGEVILREGDNADC 321 Query: 287 FYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDR 466 +V+ G DV V R K + T FGE+ L+ PR+A+V + R Sbjct: 322 LFVLVEG--DVRV---GRAGKTLTTLSRGAHFGEMGLLNQRPRSATVTTLRPVHALVLGR 376 Query: 467 HTFRRIL 487 F +L Sbjct: 377 DAFNEVL 383 >UniRef50_A0YCM5 Cluster: CAMP-binding protein-catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; n=2; unclassified Gammaproteobacteria|Rep: CAMP-binding protein-catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase - marine gamma proteobacterium HTCC2143 Length = 216 Score = 48.4 bits (110), Expect = 1e-04 Identities = 27/105 (25%), Positives = 51/105 (48%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355 +F L Q+++ + + + +I + D D+ Y+IE G V + + E ++ Sbjct: 8 IFEGLTPQELEVLASSGVMRTYPKNTVIINENDLADSLYIIETGRVKVYCSDKNGKEFIM 67 Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILL 490 +T FGELAL+ + R+ASVR + + + F ++LL Sbjct: 68 NTLGAGDYFGELALLDDDRRSASVRTLEKASFLIIYKEEFNKVLL 112 >UniRef50_Q9NQW8 Cluster: Cyclic nucleotide-gated cation channel beta 3; n=21; Tetrapoda|Rep: Cyclic nucleotide-gated cation channel beta 3 - Homo sapiens (Human) Length = 809 Score = 48.4 bits (110), Expect = 1e-04 Identities = 32/108 (29%), Positives = 55/108 (50%), Gaps = 3/108 (2%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355 LF+ D Q + +L + PG++V ++G+ G Y+I++G +V V G KV+ Sbjct: 524 LFKGCDTQMIYDMLLRLKSVLYLPGDFVCKKGEIGKEMYIIKHG--EVQVLGGPDGTKVL 581 Query: 356 HTYEGSGSFGELALMY---NMPRAASVRAQTAGALWAMDRHTFRRILL 490 T + FGE++L+ R A+V A L +D+ T + IL+ Sbjct: 582 VTLKAGSVFGEISLLAAGGGNRRTANVVAHGFANLLTLDKKTLQEILV 629 >UniRef50_Q2SDD5 Cluster: CAMP-binding protein-catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; n=3; Gammaproteobacteria|Rep: CAMP-binding protein-catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase - Hahella chejuensis (strain KCTC 2396) Length = 216 Score = 48.0 bits (109), Expect = 1e-04 Identities = 28/88 (31%), Positives = 45/88 (51%) Frame = +2 Query: 170 ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEK 349 I LF DA+Q+Q + + + VI +GD D+ Y+I +G V + ++ E Sbjct: 7 IPLFSGFDAEQLQHLEKHAVFRCFQKNSIVITEGDHSDSLYIIVSGRVRVFCSDENGKEV 66 Query: 350 VVHTYEGSGSFGELALMYNMPRAASVRA 433 ++ + FGELAL + R+ASV A Sbjct: 67 TLNDLKAGEYFGELALFDDKERSASVMA 94 >UniRef50_Q08UL3 Cluster: TrkA-N domain family; n=1; Stigmatella aurantiaca DW4/3-1|Rep: TrkA-N domain family - Stigmatella aurantiaca DW4/3-1 Length = 377 Score = 48.0 bits (109), Expect = 1e-04 Identities = 35/123 (28%), Positives = 58/123 (47%) Frame = +2 Query: 122 PKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIE 301 P A L +A+R + L + + V + G + ++GD G+ F+V+ Sbjct: 224 PSLAASITPLTQALRKVDFLTPLSDEHLAGVARGAEFLQRPAGAEIFKRGDPGETFFVVL 283 Query: 302 NGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481 G +V + GD +V+ G FGELAL+ PR A+ A +A L A+ R FR Sbjct: 284 AG--EVKLVGDGG--QVMGMVGPGGFFGELALLTGEPRMATALASSACELAAVGREDFRG 339 Query: 482 ILL 490 +++ Sbjct: 340 MVM 342 >UniRef50_A0LIE9 Cluster: Cyclic nucleotide-binding protein; n=1; Syntrophobacter fumaroxidans MPOB|Rep: Cyclic nucleotide-binding protein - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 308 Score = 48.0 bits (109), Expect = 1e-04 Identities = 30/104 (28%), Positives = 48/104 (46%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355 LFR + ++ ++ + + +VIRQGD D FYVI +G V + +E+ + Sbjct: 17 LFRDIPKDRLAEIARSAQNRIVPQHGFVIRQGDAADVFYVIASGRVRVTKKNERGMEREL 76 Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 +FGE+AL+ PRAA V A + F +L Sbjct: 77 GFLGPGDNFGEIALLTGEPRAADVVALEETRCMVFSKEQFDALL 120 >UniRef50_Q23EB3 Cluster: Cyclic nucleotide-binding domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 948 Score = 48.0 bits (109), Expect = 1e-04 Identities = 28/106 (26%), Positives = 50/106 (47%), Gaps = 2/106 (1%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL--VTGDDRVEK 349 +F Q + +++ M E PGE + +GD D+ Y+I +G ++L + + Sbjct: 442 IFNCFSQQSINKLVFFMKEIILSPGEVIFSEGDIDDSIYLINSGQIEILRNTAHKNCLSF 501 Query: 350 VVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 + T + FGELA MPR A+ + L+ ++R F I+ Sbjct: 502 QLKTLSENQIFGELAFFSQMPRTATAKCIKLSMLYKIERKDFIEII 547 >UniRef50_A7SFW1 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 968 Score = 48.0 bits (109), Expect = 1e-04 Identities = 26/68 (38%), Positives = 41/68 (60%) Frame = +2 Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403 + E G + QGD+GD++Y+I G +V+V G V + +HT++ FG L+L+ Sbjct: 330 VLESCEHKGTVLFNQGDEGDSWYIILKGSVNVVVLGKGIVCQ-LHTWD---DFGRLSLVN 385 Query: 404 NMPRAASV 427 N PRAAS+ Sbjct: 386 NAPRAASI 393 Score = 35.9 bits (79), Expect = 0.55 Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 2/86 (2%) Frame = +2 Query: 173 LLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKV 352 L+F+ + ++Q+ + + EPG + RQ G N+Y I G ++ V+ ++E Sbjct: 13 LVFKKVHPHVVRQICFYAYYEDLEPGTVLYRQDAKGLNWYAILTGSVNICVSQTSKIEDA 72 Query: 353 VH-TYEGSGS-FGELALMYNMPRAAS 424 V G GS FGE +++ PR A+ Sbjct: 73 VTLCCLGPGSTFGE-SVLDGSPRTAT 97 >UniRef50_UPI0000F1F638 Cluster: PREDICTED: similar to putative cNMP-gated potassium channel; n=2; Danio rerio|Rep: PREDICTED: similar to putative cNMP-gated potassium channel - Danio rerio Length = 1716 Score = 47.6 bits (108), Expect = 2e-04 Identities = 23/79 (29%), Positives = 42/79 (53%) Frame = +2 Query: 251 EYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVR 430 + + ++GD G Y +E G +VL + KV+ FGE +L+++ PRAA++R Sbjct: 1099 DVIYKKGDCGSEVYFVEKGEVEVLSNNES---KVLFKLSAGQYFGERSLLFHEPRAATIR 1155 Query: 431 AQTAGALWAMDRHTFRRIL 487 A T ++ + + + IL Sbjct: 1156 AATNSEMYVLSQKSLHEIL 1174 Score = 36.7 bits (81), Expect = 0.31 Identities = 20/65 (30%), Positives = 32/65 (49%) Frame = +2 Query: 245 PGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAAS 424 PG+ + + G+ N Y I++G V E + T FGE+ L+Y +PR + Sbjct: 171 PGQTLAKAGEINQNLYYIKHGHVQVF---SQNPEVEIATLLPGTLFGEVHLLYEIPRNVT 227 Query: 425 VRAQT 439 +RA T Sbjct: 228 IRAST 232 >UniRef50_UPI00006CFEF7 Cluster: cation channel family protein; n=1; Tetrahymena thermophila SB210|Rep: cation channel family protein - Tetrahymena thermophila SB210 Length = 1392 Score = 47.6 bits (108), Expect = 2e-04 Identities = 38/175 (21%), Positives = 73/175 (41%), Gaps = 13/175 (7%) Frame = +2 Query: 2 EXYFVKKPPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPK-SDAQRARLAEAVRGILL 178 + Y +K +R +S Y ++D + E VF K S+ R + + + G ++ Sbjct: 605 QRYLNRKNVNISLKSRVRSYLVFLYKEQKDRNQEAEEKVFQKLSNKLRREIVQEINGKIV 664 Query: 179 ------FRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGD-NFYVIENGVFDVLVTGDD 337 ++ + + +++ AM E P E + +GD D + Y I+ G D+ D Sbjct: 665 NSCGIFTKNFSSSTINKIIFAMKECVVSPNEIIFNEGDQDDMSIYFIQGGYVDIFQQNDS 724 Query: 338 RVEK-----VVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 K V+ + FGEL+ +PR A ++ L+ + F +I+ Sbjct: 725 DKNKQSNQRVIKRLGQNQIFGELSFFSGLPRKAGAKSVNLTTLYKLAADDFLKIV 779 >UniRef50_Q5NXU3 Cluster: Catabolite gene activator; n=3; Rhodocyclaceae|Rep: Catabolite gene activator - Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) Length = 223 Score = 47.6 bits (108), Expect = 2e-04 Identities = 33/111 (29%), Positives = 55/111 (49%), Gaps = 1/111 (0%) Frame = +2 Query: 158 AVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDD 337 A++ LF+ L + V +R G+ V+ G+ D Y++ G V+V+ +D Sbjct: 11 ALKTFSLFQGLSDDTLATVSRLAMMRRIPRGQSVVHAGERCDFVYLVLTGSLKVVVSDED 70 Query: 338 RVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 E V+ T G G FGE+++ PR+A+V A L + ++ FR IL Sbjct: 71 GRE-VILTILGQGELFGEMSMFGEQPRSATVVAVMPSDLVMIAKNDFRTIL 120 >UniRef50_Q2RK98 Cluster: Transcriptional regulator, Crp/Fnr family; n=2; Clostridia|Rep: Transcriptional regulator, Crp/Fnr family - Moorella thermoacetica (strain ATCC 39073) Length = 225 Score = 47.6 bits (108), Expect = 2e-04 Identities = 22/92 (23%), Positives = 43/92 (46%) Frame = +2 Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334 E +R + +F L+ +++Q + +R Y+ +G+ GD FY ++ G + + Sbjct: 6 EFLRQVPVFAGLEPEELQHIASLALLRRYRKNMYIFMEGEPGDAFYFVKKGAIKLFQVLE 65 Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVR 430 D EK++H F E+ L P A+ + Sbjct: 66 DGREKILHFVREGEIFAEVLLFEGGPYPATAQ 97 >UniRef50_Q935V9 Cluster: Transcriptional regulator with cyclic nucleotide-binding domain; n=2; Streptomyces|Rep: Transcriptional regulator with cyclic nucleotide-binding domain - Streptomyces sp. EC3 Length = 227 Score = 47.6 bits (108), Expect = 2e-04 Identities = 25/82 (30%), Positives = 41/82 (50%) Frame = +2 Query: 242 EPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAA 421 E GE ++R+G+ G + Y++ +G + V+ +D E ++ G GELA +PR A Sbjct: 48 EKGERLLREGEQGSHVYLLLSGWYKVVARTEDDREALMAVRTGGDIVGELACFGTLPRVA 107 Query: 422 SVRAQTAGALWAMDRHTFRRIL 487 +V A G + R F L Sbjct: 108 TVMAAGPGVTRLIGRQEFNDFL 129 >UniRef50_Q7D4Z5 Cluster: Drug transporter; n=19; Mycobacterium|Rep: Drug transporter - Mycobacterium tuberculosis Length = 1071 Score = 47.6 bits (108), Expect = 2e-04 Identities = 47/154 (30%), Positives = 67/154 (43%) Frame = +2 Query: 23 PPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQ 202 PPVA RR A P A A PK+ ++ L EA+R F D QQ Sbjct: 504 PPVAPLGARRPPRPAPVASPA------AAVAPTPKT-SREVNLLEALR----FARPDTQQ 552 Query: 203 MQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF 382 ++ + G Y+ GD D YV+ +G VL GD ++VV Sbjct: 553 IEL----------QAGSYLFHAGDVSDALYVVRSGRLQVLA-GDGAKDEVVAELGRGQVV 601 Query: 383 GELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484 GEL ++ + PR+ASVRA +L + + F +I Sbjct: 602 GELGVLLDAPRSASVRAVRDSSLMRVTKAEFAKI 635 >UniRef50_Q05VE2 Cluster: Possible mechanosensitive ion channel; n=2; Synechococcus|Rep: Possible mechanosensitive ion channel - Synechococcus sp. RS9916 Length = 494 Score = 47.6 bits (108), Expect = 2e-04 Identities = 37/134 (27%), Positives = 58/134 (43%), Gaps = 5/134 (3%) Frame = +2 Query: 80 PEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYV 259 P D E PA P S + + +F L QQ+ + + PGE V Sbjct: 303 PVRDIRTEPVPARLPSSAVNPGQKQRLLACTDIFGHLSDQQLGALAANASCQSFAPGETV 362 Query: 260 IRQGDDGDNFYVIENGVFDVL-VTGDDRVEKV----VHTYEGSGSFGELALMYNMPRAAS 424 +RQG+ GD+ +++ +G DV +G + + V + S FGE+AL R+AS Sbjct: 363 VRQGERGDSLFLVVSGSLDVFQASGTNPARSLPGQQVASLHSSDIFGEMALCTGEARSAS 422 Query: 425 VRAQTAGALWAMDR 466 V L ++R Sbjct: 423 VVCNNECVLIEIER 436 >UniRef50_A6GAV1 Cluster: Protein phosphatase/cyclic nucleotide-binding domain protein; n=1; Plesiocystis pacifica SIR-1|Rep: Protein phosphatase/cyclic nucleotide-binding domain protein - Plesiocystis pacifica SIR-1 Length = 591 Score = 47.6 bits (108), Expect = 2e-04 Identities = 33/113 (29%), Positives = 56/113 (49%) Frame = +2 Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334 + ++ I LF L+ QQ+ ++++ EP + + +G G+ +VI G D+ Sbjct: 269 DTLKQIPLFSELNYQQLVRIMNLTRIVPFEPRDILCYEGQIGEELFVILRGEVDLY---- 324 Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLK 493 R + + FGE+AL+ MPR+A+ A T G L ++R F IL K Sbjct: 325 -RNDVPFASLPQGAHFGEMALIDAMPRSATAVAATHGKLLMINREDFLEILRK 376 >UniRef50_A0P0J2 Cluster: Putative catabolite gene activator; n=2; Stappia aggregata IAM 12614|Rep: Putative catabolite gene activator - Stappia aggregata IAM 12614 Length = 250 Score = 47.6 bits (108), Expect = 2e-04 Identities = 29/108 (26%), Positives = 49/108 (45%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355 +F +LDAQ + + F K+ GE + G G + I G V + E + Sbjct: 34 IFDALDAQAREDLARFAFLKKFSAGEVIFTMGTLGQSMMAIAEGTVRVSMFTPSGGEVTL 93 Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSA 499 + FGE+AL+ R+ASV+A T + ++R F +L + + Sbjct: 94 TDLKTGDVFGEIALLDGQERSASVKALTNCTVVVLERRNFLEVLRRDS 141 >UniRef50_Q45ZY2 Cluster: Hyperpolarization-gated and cyclic nucleotide regulated channel; n=1; Strongylocentrotus purpuratus|Rep: Hyperpolarization-gated and cyclic nucleotide regulated channel - Strongylocentrotus purpuratus (Purple sea urchin) Length = 638 Score = 47.6 bits (108), Expect = 2e-04 Identities = 27/80 (33%), Positives = 44/80 (55%) Frame = +2 Query: 248 GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASV 427 G+ +I+ G G Y IE+G +VLV DDR +V+ FGE++L+ + R AS+ Sbjct: 481 GDVIIKAGSLGGAMYFIEHGTVEVLV--DDR---IVNRLSDGDHFGEISLLIDERRVASI 535 Query: 428 RAQTAGALWAMDRHTFRRIL 487 A T ++ + R F ++L Sbjct: 536 IAATTCDVFCLSREDFHKVL 555 >UniRef50_Q24DS4 Cluster: Cation channel family protein; n=1; Tetrahymena thermophila SB210|Rep: Cation channel family protein - Tetrahymena thermophila SB210 Length = 2194 Score = 47.6 bits (108), Expect = 2e-04 Identities = 27/113 (23%), Positives = 56/113 (49%), Gaps = 4/113 (3%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDN--FYVIENGVFDVL--VT 328 + I LF+ + ++ ++ M E+ PGE + QGD DN +Y+++ V + + Sbjct: 545 LNNIPLFKHI--KEKDKIAKIMEEQLYSPGEMIFHQGDQDDNSLYYIVKGSVSIIFNPTS 602 Query: 329 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 +R K +H + FGE++ + PR S +A ++ ++R F +++ Sbjct: 603 NQNREAKQIHLIKKKEYFGEISFINGNPRTFSAKAADFCRIYKINRQQFIQVI 655 Score = 36.3 bits (80), Expect = 0.41 Identities = 25/114 (21%), Positives = 51/114 (44%), Gaps = 4/114 (3%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGD-DGDNFYVIENGVFDVLVTGD- 334 + I LF+ + ++ ++ M E PGE + QGD D + Y I G ++ + Sbjct: 1632 LNNIPLFKHI--KEKDKIAKIMEEHLYSPGETIFNQGDLDDSSLYYIVKGSVSIIFNPEN 1689 Query: 335 --DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILL 490 +R K + + FGE++ + PR + + ++ ++R F + +L Sbjct: 1690 NPNREAKQIQLVKKKEYFGEISFISGNPRTFTAKTADFCRIYKINRQQFLQTVL 1743 >UniRef50_Q59V20 Cluster: Putative uncharacterized protein; n=1; Candida albicans|Rep: Putative uncharacterized protein - Candida albicans (Yeast) Length = 721 Score = 47.6 bits (108), Expect = 2e-04 Identities = 32/104 (30%), Positives = 50/104 (48%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355 LF++ +QV + P E++I++GD + Y I G V VT D E Sbjct: 58 LFKNAPTSFHKQVAANLRLIHYRPQEFIIKKGDLSRSMYWILKGT--VSVTSTDGEEVYA 115 Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 +G FGE+ ++YN PR A+V A+T L + + R+L Sbjct: 116 ELNQGE-FFGEIGILYNRPRTATVIAKTRILLGVLTAESLNRVL 158 Score = 33.1 bits (72), Expect = 3.9 Identities = 26/111 (23%), Positives = 53/111 (47%), Gaps = 2/111 (1%) Frame = +2 Query: 113 AVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDD-GDNF 289 A+ K + + + + + LF+ L + ++ ++ P EY++R+GD GD + Sbjct: 177 AMQDKKNKEPLSIQSFITNLPLFQFLPPDIIHKLALSVEPLVFSPFEYILRKGDTCGDIY 236 Query: 290 YVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQT 439 ++IE +V V + V ++ SGS FGE++ + + +R T Sbjct: 237 FIIEG---EVEVLNQEGVIEIPLARLSSGSYFGEMSFLNYLQNKPRIRTAT 284 >UniRef50_Q8XR93 Cluster: Probable transcription regulator protein; n=6; Ralstonia|Rep: Probable transcription regulator protein - Ralstonia solanacearum (Pseudomonas solanacearum) Length = 225 Score = 47.2 bits (107), Expect = 2e-04 Identities = 25/86 (29%), Positives = 40/86 (46%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355 LF LDA+ + + + R ++V +GD D FYV+ G +++ G KV+ Sbjct: 16 LFEGLDAEDLATLARDSHQIRLARHDFVFHRGDCADGFYVVAVGTIKLVLPGAHGHNKVI 75 Query: 356 HTYEGSGSFGELALMYNMPRAASVRA 433 + FGE + N P AA +A Sbjct: 76 EFFGPGEYFGEPFMFLNQPHAADAQA 101 >UniRef50_Q2K3Q8 Cluster: Probable cation transporter protein; n=2; Rhizobium|Rep: Probable cation transporter protein - Rhizobium etli (strain CFN 42 / ATCC 51251) Length = 581 Score = 47.2 bits (107), Expect = 2e-04 Identities = 33/115 (28%), Positives = 53/115 (46%), Gaps = 1/115 (0%) Frame = +2 Query: 146 RLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDV-L 322 ++ + + LF + +++L K + PGE VIR+GD GD+ Y I +G +V L Sbjct: 440 KMQQLIETFPLFSQVGEDAQEELLLLFKAKSAPPGERVIRRGDRGDSMYFISSGAVEVRL 499 Query: 323 VTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 +G R+E FGE+AL+ R A V A ++R F + Sbjct: 500 ASGAIRLEP-------GAFFGEMALLSGGRRTADVIAVDFCQFEVLERRDFNMFM 547 >UniRef50_Q1NMR4 Cluster: Cyclic nucleotide-binding; n=2; delta proteobacterium MLMS-1|Rep: Cyclic nucleotide-binding - delta proteobacterium MLMS-1 Length = 358 Score = 47.2 bits (107), Expect = 2e-04 Identities = 26/66 (39%), Positives = 36/66 (54%), Gaps = 1/66 (1%) Frame = +2 Query: 245 PGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF-GELALMYNMPRAA 421 PGE + +GD G + Y IE G ++ V D R V++T G+G G L + PR A Sbjct: 13 PGELLFNKGDPGGDLYFIEQGSLEIFVYQDGR--PVIYTEMGAGEIVGVLTCLTGEPRMA 70 Query: 422 SVRAQT 439 S RA+T Sbjct: 71 SARAKT 76 >UniRef50_Q0LJ13 Cluster: Cyclic nucleotide-binding; n=2; Chloroflexi (class)|Rep: Cyclic nucleotide-binding - Herpetosiphon aurantiacus ATCC 23779 Length = 166 Score = 47.2 bits (107), Expect = 2e-04 Identities = 25/96 (26%), Positives = 51/96 (53%), Gaps = 5/96 (5%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV----- 325 +R + +F L+ ++ Q+ +++ G+ + R+ DGD+ YV+ +G ++ V Sbjct: 9 LRRVDIFAGLNDLELSQIAQLCKVAKAKKGQIIFREDSDGDDLYVVHDGAVEIQVQTRGS 68 Query: 326 TGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 433 G R+ + YEG +FGE+A++ R+A+ A Sbjct: 69 DGQHRLSTINTAYEGQ-AFGEIAMLGGGSRSATAVA 103 >UniRef50_A4XWI5 Cluster: Cyclic nucleotide-binding protein; n=2; Pseudomonas|Rep: Cyclic nucleotide-binding protein - Pseudomonas mendocina ymp Length = 369 Score = 47.2 bits (107), Expect = 2e-04 Identities = 32/105 (30%), Positives = 52/105 (49%), Gaps = 1/105 (0%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV-TGDDRVEKV 352 LF + +Q +L + G V+ +G GD + +E+G +V+ G DR +V Sbjct: 144 LFAKVPPANVQSMLGRLQRIEVAAGSQVLEEGAAGDCCFFLESGRAEVIRRAGSDR--QV 201 Query: 353 VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 + E FGE AL+ + PR A+V AG++ +DR F +L Sbjct: 202 LAELEVGACFGEEALLADRPRNATVTMVEAGSVLRLDRQDFFALL 246 >UniRef50_A1ZHX6 Cluster: Serine/threonine protein kinases; n=1; Microscilla marina ATCC 23134|Rep: Serine/threonine protein kinases - Microscilla marina ATCC 23134 Length = 455 Score = 47.2 bits (107), Expect = 2e-04 Identities = 28/123 (22%), Positives = 52/123 (42%) Frame = +2 Query: 122 PKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIE 301 P D A ++ + +F D + + + E+ +I++GD G++ Y+I Sbjct: 4 PVKDIDLAEKVAILKTVKVFAETDQDVLVNIAKVLTEEHHPKDSLIIKKGDPGESMYIIV 63 Query: 302 NGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481 +G V G V FGE AL+ PR+A V LW +++ F + Sbjct: 64 DGAVRVHDGGYTFV-----VLRNRNVFGEYALLDTKPRSADVTTLRRTRLWKLNQDVFYK 118 Query: 482 ILL 490 +++ Sbjct: 119 VMM 121 >UniRef50_A0L6N5 Cluster: Cyclic nucleotide-binding; n=1; Magnetococcus sp. MC-1|Rep: Cyclic nucleotide-binding - Magnetococcus sp. (strain MC-1) Length = 729 Score = 47.2 bits (107), Expect = 2e-04 Identities = 27/106 (25%), Positives = 52/106 (49%), Gaps = 1/106 (0%) Frame = +2 Query: 173 LLFRSLDAQQMQ-QVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEK 349 LL R + + +M ++L + E + G+ + QG+ D Y+IE+G + + D K Sbjct: 590 LLTRIMGSTEMATRILPYLKELSLKSGDILFEQGEVTDGLYIIESGKIAIYFSHPDGWTK 649 Query: 350 VVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 V E GE+ L + +PR+A+ + +G + ++R+L Sbjct: 650 QVRILEQGTLVGEMGLYHTLPRSAAAIVEESGIVHHFSHANYQRLL 695 >UniRef50_Q554K9 Cluster: CGMP-stimulated cGMP phosphodiesterase; n=2; Dictyostelium discoideum|Rep: CGMP-stimulated cGMP phosphodiesterase - Dictyostelium discoideum AX4 Length = 867 Score = 47.2 bits (107), Expect = 2e-04 Identities = 32/127 (25%), Positives = 63/127 (49%) Frame = +2 Query: 116 VFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYV 295 V S ++ + + V + +FRS+ Q ++L +++ G +I + + D FYV Sbjct: 587 VMKSSHSEAVDILKLVESVDIFRSIPLTQACEILQTATKRKYSQGSVIIARDTEPDAFYV 646 Query: 296 IENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTF 475 + +GV V + G+ + +V Y FGE++L+ R+A+V+A T + + ++ F Sbjct: 647 VASGVVCVNI-GELKKNLIVGDY-----FGEMSLVMGGLRSANVQAVTDVEVLSFNKEDF 700 Query: 476 RRILLKS 496 I S Sbjct: 701 LSITRNS 707 >UniRef50_A0CLY8 Cluster: Chromosome undetermined scaffold_21, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_21, whole genome shotgun sequence - Paramecium tetraurelia Length = 513 Score = 47.2 bits (107), Expect = 2e-04 Identities = 28/96 (29%), Positives = 47/96 (48%), Gaps = 1/96 (1%) Frame = +2 Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVE-KVVHTYEGSGSFGELALM 400 M+ ++ + E V G FY+I G VLV ++ + + V SFGELAL+ Sbjct: 57 MYCEKFKASEIVFYVDSVGTKFYIILEGSVTVLVRKPNQSDMEAVRILNKGESFGELALL 116 Query: 401 YNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKK 508 + PR A+++ T +D+ F+ IL + K+ Sbjct: 117 HKQPRLATIQCNTDCTFAVLDKQQFKHILQEEQQKQ 152 >UniRef50_O95398 Cluster: Rap guanine nucleotide exchange factor 3; n=33; Euteleostomi|Rep: Rap guanine nucleotide exchange factor 3 - Homo sapiens (Human) Length = 881 Score = 47.2 bits (107), Expect = 2e-04 Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 1/89 (1%) Frame = +2 Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403 +FE S+ G + QGD G ++Y+I G +V+ G + +V T FG+LAL+ Sbjct: 220 LFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHG----KGLVTTLHEGDDFGQLALVN 275 Query: 404 NMPRAASVRAQTAGA-LWAMDRHTFRRIL 487 + PRAA++ + +D+ F RI+ Sbjct: 276 DAPRAATIILREDNCHFLRVDKQDFNRII 304 >UniRef50_Q7V424 Cluster: Possible mechanosensitive ion channel; n=1; Prochlorococcus marinus str. MIT 9313|Rep: Possible mechanosensitive ion channel - Prochlorococcus marinus (strain MIT 9313) Length = 496 Score = 46.8 bits (106), Expect = 3e-04 Identities = 31/105 (29%), Positives = 50/105 (47%), Gaps = 1/105 (0%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355 LF L Q+ + + R GE +IRQG+ GD Y + G +V T + + +K+ Sbjct: 339 LFTDLSQAQLDALAPSTRCVRFAKGETIIRQGESGDCLYQMITGTVEVSQT-NSQGQKIT 397 Query: 356 HTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 G FGE+AL PR ++VRA L ++R + ++ Sbjct: 398 FQKLGQHEIFGEMALCTKQPRNSTVRALEESVLLEVERRDLQPLI 442 >UniRef50_Q9X7J4 Cluster: DnrD protein; n=9; Pseudomonas|Rep: DnrD protein - Pseudomonas stutzeri (Pseudomonas perfectomarina) Length = 227 Score = 46.8 bits (106), Expect = 3e-04 Identities = 28/112 (25%), Positives = 51/112 (45%), Gaps = 1/112 (0%) Frame = +2 Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334 + +R LF L+ +QM+++L+A + G+ + QG+ NFY + +G V Sbjct: 9 QILRSHHLFEPLNEEQMEELLNASQLLNLDKGDNLFHQGEPAHNFYFVISGAVKVYRLTP 68 Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPR-AASVRAQTAGALWAMDRHTFRRIL 487 D EKV +F E ++ + P AS +A ++ + R+L Sbjct: 69 DGQEKVFEVIGNRQTFAEAMMLMDTPNYVASAQAVCPSQVYRFSNAAYMRLL 120 >UniRef50_Q1YDI6 Cluster: Possible cAMP-dependent regulatory protein; n=1; Aurantimonas sp. SI85-9A1|Rep: Possible cAMP-dependent regulatory protein - Aurantimonas sp. SI85-9A1 Length = 158 Score = 46.8 bits (106), Expect = 3e-04 Identities = 28/111 (25%), Positives = 57/111 (51%) Frame = +2 Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334 + +R + +F ++ +++ + G+ + RQG+ GD+ YVI G DV + + Sbjct: 9 DLLRSVPIFAGMEPSRLKLIAFTSDSIAYRQGQVMCRQGERGDSAYVIVAGKADVSIETE 68 Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 D + VV T GE+A++ + PR A+V A++ + + + F ++L Sbjct: 69 DG-DFVVATLGPGDVVGEIAILCDTPRTATVTAKSDVSALRVRKECFLQLL 118 >UniRef50_A7SKJ9 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1023 Score = 46.8 bits (106), Expect = 3e-04 Identities = 26/91 (28%), Positives = 45/91 (49%) Frame = +2 Query: 242 EPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAA 421 +PG+Y++ GD G Y I G ++L + V+ T FGE+ L+Y R A Sbjct: 45 KPGDYIVYAGDMGREMYCIRRGQVNILCE-----DNVIGTLGPGSFFGEIGLIYGESRFA 99 Query: 422 SVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 +V+A+T + + +H +L + KR+ Sbjct: 100 TVQAKTYCQILMLTKHDLDEVLEEFPIIKRQ 130 Score = 34.7 bits (76), Expect = 1.3 Identities = 21/81 (25%), Positives = 43/81 (53%), Gaps = 1/81 (1%) Frame = +2 Query: 248 GEYVIRQGDDGDNFYVIENGVFDVLVTGD-DRVEKVVHTYEGSGSFGELALMYNMPRAAS 424 GEY+IR+GD G +++ G ++ + D +++E++V + + + L+ P S Sbjct: 920 GEYIIRKGDIGQQLIILKRGTAAIVKSEDPEKLEEMV----VNSFYSQRYLLLTGPYLES 975 Query: 425 VRAQTAGALWAMDRHTFRRIL 487 VRA T ++ +D+ +L Sbjct: 976 VRAITNVDVFLLDKKDLYEVL 996 >UniRef50_P34578 Cluster: Uncharacterized protein T20G5.5; n=2; Caenorhabditis|Rep: Uncharacterized protein T20G5.5 - Caenorhabditis elegans Length = 1234 Score = 46.8 bits (106), Expect = 3e-04 Identities = 28/87 (32%), Positives = 47/87 (54%), Gaps = 1/87 (1%) Frame = +2 Query: 230 EKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNM 409 E+ G V RQG+ G +Y++ G +V V G K+V FG+LAL+ ++ Sbjct: 590 EQYVHAGSVVFRQGEIGVYWYIVLKGAVEVNVNG-----KIVCLLREGDDFGKLALVNDL 644 Query: 410 PRAASVRAQTAGALW-AMDRHTFRRIL 487 PRAA++ +++ +D+H F +IL Sbjct: 645 PRAATIVTYEDDSMFLVVDKHHFNQIL 671 >UniRef50_UPI000065E24B Cluster: Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP).; n=1; Takifugu rubripes|Rep: Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP). - Takifugu rubripes Length = 908 Score = 46.4 bits (105), Expect = 4e-04 Identities = 29/89 (32%), Positives = 48/89 (53%), Gaps = 1/89 (1%) Frame = +2 Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403 +FE ++ G + QGD G ++Y+I G +V+ G V + +EG FG+LAL+ Sbjct: 172 VFESHAKAGTVLFSQGDKGTSWYIIWKGSVNVITHGKGLVTTL---HEGE-DFGQLALLN 227 Query: 404 NMPRAASVRAQTAGA-LWAMDRHTFRRIL 487 + PRAA++ + +D+ F RIL Sbjct: 228 DAPRAATIILREDNCHFLRVDKQDFIRIL 256 >UniRef50_Q92SD2 Cluster: PUTATIVE TRANSCRIPTION REGULATOR PROTEIN; n=2; Sinorhizobium|Rep: PUTATIVE TRANSCRIPTION REGULATOR PROTEIN - Rhizobium meliloti (Sinorhizobium meliloti) Length = 234 Score = 46.4 bits (105), Expect = 4e-04 Identities = 24/108 (22%), Positives = 50/108 (46%) Frame = +2 Query: 164 RGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRV 343 R +F D++ + ++ ++ G + ++GD GD V+ +G + + Sbjct: 12 RSFPIFEEFDSETLCELSGIASYRKWSAGTVIFQRGDQGDYMIVVVSGRIKLSLFTPQGR 71 Query: 344 EKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 E ++ +E FGE+AL+ PR+A A TA + + + F ++ Sbjct: 72 ELMLRQHEAGALFGEMALLDGQPRSADATAVTAAEGYVIGKKDFLALI 119 >UniRef50_Q30Y06 Cluster: Transcriptional regulator, Crp/Fnr family; n=3; Desulfovibrio|Rep: Transcriptional regulator, Crp/Fnr family - Desulfovibrio desulfuricans (strain G20) Length = 248 Score = 46.4 bits (105), Expect = 4e-04 Identities = 21/79 (26%), Positives = 39/79 (49%) Frame = +2 Query: 170 ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEK 349 I LF L AQQ++ + ++ + G+ + +G + Y++ +G + T D E Sbjct: 31 IPLFSGLSAQQLESMASIAVDRPVDKGQIIFVEGTRAEGLYIVLDGRVKIFKTAPDGREA 90 Query: 350 VVHTYEGSGSFGELALMYN 406 V+H + FGE+A+ N Sbjct: 91 VMHVFGAGEPFGEVAVFQN 109 >UniRef50_Q7CWQ8 Cluster: AGR_C_4670p; n=6; Rhizobiaceae|Rep: AGR_C_4670p - Agrobacterium tumefaciens (strain C58 / ATCC 33970) Length = 162 Score = 46.4 bits (105), Expect = 4e-04 Identities = 27/95 (28%), Positives = 47/95 (49%) Frame = +2 Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334 + ++ + F ++ +++ + A G+ + RQGD GD YV+ G DVLV Sbjct: 19 QMLKRVPFFSEMEPSKLKLLAFASDRVSYHAGDTLFRQGDVGDAAYVLLTGKVDVLVDSP 78 Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 439 KV G+ GE+A++ + R A++RA T Sbjct: 79 SGTLKVAE-MTGNAIVGEIAILCDSVRTATIRAST 112 >UniRef50_Q236Y9 Cluster: Cyclic nucleotide-binding domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 983 Score = 46.4 bits (105), Expect = 4e-04 Identities = 27/102 (26%), Positives = 49/102 (48%), Gaps = 1/102 (0%) Frame = +2 Query: 206 QQVLDAMFEKRSEPGEYVIRQGDDGD-NFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF 382 +++ M E PGEY+ ++ D D + Y+I G D++ T + R E ++ T + F Sbjct: 321 KEIAIIMEEVIFSPGEYIYQKDDVDDCSLYLIVKGQVDIVFTSEKRGESIIQTLDKLKYF 380 Query: 383 GELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKK 508 GE + + R S +A T ++ + R+ F + F K Sbjct: 381 GEQSFISGFQRELSAKAATFCRVYKIPRNKFLETIKLYDFDK 422 >UniRef50_A0CY63 Cluster: Chromosome undetermined scaffold_301, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_301, whole genome shotgun sequence - Paramecium tetraurelia Length = 785 Score = 46.4 bits (105), Expect = 4e-04 Identities = 28/57 (49%), Positives = 34/57 (59%), Gaps = 5/57 (8%) Frame = +2 Query: 245 PGEYVIRQGDDGDNFYVIENGVFDVLV----TGDDRV-EKVVHTYEGSGSFGELALM 400 PGEYV QGD GDN +VI +G DV + T D V E+VV + FGELA+M Sbjct: 297 PGEYVFHQGDFGDNLFVILSGSVDVKIEKKFTQDGPVIEQVVSSLYDGQHFGELAMM 353 >UniRef50_P0A642 Cluster: Uncharacterized NTE family protein Rv2565/MT2641; n=7; Mycobacterium tuberculosis complex|Rep: Uncharacterized NTE family protein Rv2565/MT2641 - Mycobacterium tuberculosis Length = 583 Score = 46.4 bits (105), Expect = 4e-04 Identities = 29/122 (23%), Positives = 60/122 (49%) Frame = +2 Query: 122 PKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIE 301 PK AR A +R + + +D +Q++++ + + +++ G+ D+ Y+++ Sbjct: 8 PKRRGTDARTA--LRNVPILADIDDEQLERLATTVERRHVPANQWLFHAGEPADSIYIVD 65 Query: 302 NGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481 +G F V V + V + + + S G+L ++ R+A VRA G +W + TF Sbjct: 66 SGRF-VAVAPEGHVFAEMASGD---SIGDLGVIAGAARSAGVRALRDGVVWRIAAETFTD 121 Query: 482 IL 487 +L Sbjct: 122 ML 123 >UniRef50_UPI00015BC926 Cluster: UPI00015BC926 related cluster; n=1; unknown|Rep: UPI00015BC926 UniRef100 entry - unknown Length = 219 Score = 46.0 bits (104), Expect = 5e-04 Identities = 25/114 (21%), Positives = 53/114 (46%) Frame = +2 Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334 + +R + LF + + ++++ + + GE V +GD +N Y++ +G+ V + Sbjct: 6 DLLRNVYLFSKVSDENLKKLKSISNIRNFKKGEIVFHEGDKPENIYILLDGLVKVYKLTN 65 Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKS 496 E V+ ++ GE+A N+ A+ T G + +D F+R + S Sbjct: 66 KGTEVVITQFKPVSIIGEMANFENISYPATAEFITEGQVLQIDFEAFKREFMTS 119 >UniRef50_UPI00006CE543 Cluster: cyclic nucleotide-binding domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 637 Score = 46.0 bits (104), Expect = 5e-04 Identities = 29/111 (26%), Positives = 54/111 (48%), Gaps = 5/111 (4%) Frame = +2 Query: 191 DAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVE-----KVV 355 D + + ++ K+ E ++V +QG+ GD FY+I G + + + K V Sbjct: 210 DIPEFIDICRNLYIKQYEKKQFVFKQGEYGDAFYIILYGSVTIYIDEPTEYKSFMQLKEV 269 Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKK 508 E +FGE+AL+Y+ R A+V A L ++++ F+ + + F K Sbjct: 270 AKLEQGDTFGEIALIYDSQRTATVIANEKTYLVVLEKNIFQSYIKQIDFFK 320 >UniRef50_UPI00006CB774 Cluster: cyclic nucleotide-binding domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 873 Score = 46.0 bits (104), Expect = 5e-04 Identities = 29/103 (28%), Positives = 52/103 (50%), Gaps = 3/103 (2%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDD-RVEKV 352 LF L + + ++DA+ + E G+ + ++GD G F++I++G + ++ +++KV Sbjct: 582 LFEDLSIKHAKHLIDAVQVEEYEKGDIIFKEGDIGHKFFIIQSGAVRIYTDNENIQIDKV 641 Query: 353 --VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTF 475 V Y G GS L + R A A T L ++RH F Sbjct: 642 FKVGDYFGEGSL----LDSSNKRIAQAEAITDCQLLTLERHDF 680 >UniRef50_Q2W0I8 Cluster: Kef-type K+ transport systems, predicted NAD-binding component; n=3; Magnetospirillum|Rep: Kef-type K+ transport systems, predicted NAD-binding component - Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) Length = 394 Score = 46.0 bits (104), Expect = 5e-04 Identities = 30/109 (27%), Positives = 52/109 (47%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340 V + F+ L A Q+ ++ + R+ GE ++R+GD G+ Y I +G +V Sbjct: 254 VAKVPFFQRLQASQIAEIAGLLKLARAIKGEVLMREGDTGECMYFIVSGQVEVKGRAGTF 313 Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 + K FGE+AL+ PR A+V+A + L +D F + + Sbjct: 314 ILK------NGDFFGEIALIERCPRTATVKAVSRCQLLILDARDFHKFV 356 >UniRef50_Q0VS63 Cluster: Cyclic nucleotide-binding protein; n=1; Alcanivorax borkumensis SK2|Rep: Cyclic nucleotide-binding protein - Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) Length = 153 Score = 46.0 bits (104), Expect = 5e-04 Identities = 28/107 (26%), Positives = 48/107 (44%) Frame = +2 Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355 LF L ++ + +F R G+ V R+GD D + G D++ + E V+ Sbjct: 13 LFAGLSEDELAILEKLVFVNRVPVGDVVCREGDRSDFVCFVVRGCLDIVKNNEGGGEVVI 72 Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKS 496 GE+AL+ + PR+A+VRA L + R ++ +S Sbjct: 73 AHLRPGDCMGEMALVDHEPRSATVRAAEDATLIVLTRKGIEQLRKRS 119 >UniRef50_A0E9X9 Cluster: Chromosome undetermined scaffold_85, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_85, whole genome shotgun sequence - Paramecium tetraurelia Length = 340 Score = 46.0 bits (104), Expect = 5e-04 Identities = 26/106 (24%), Positives = 56/106 (52%), Gaps = 1/106 (0%) Frame = +2 Query: 182 RSLDAQQMQQVLDAMFE-KRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVH 358 R + + + QV+ + + ++ + + + GD G+ FYVI G+ V V +D++ + Sbjct: 11 RIIVGEDLYQVIKSKMQIEQYSVNDVLTKIGDKGNKFYVILQGLVGVFVRNEDQLTMINV 70 Query: 359 TYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKS 496 EG G GEL++M N R A++ T + + + ++R ++++ Sbjct: 71 CREGEG-MGELSIMSNKSRMATLVCLTDCVIATLTAYQYKRYVMQN 115 >UniRef50_A0CUC4 Cluster: Chromosome undetermined scaffold_28, whole genome shotgun sequence; n=4; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_28, whole genome shotgun sequence - Paramecium tetraurelia Length = 470 Score = 46.0 bits (104), Expect = 5e-04 Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 13/101 (12%) Frame = +2 Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR-------------VEKVVHTY 364 ++ K E +Y+ +QGD GD FYVI NG V + ++K + Sbjct: 74 LYLKTYEKRQYIFKQGDQGDAFYVILNGSVKVYIDEPTEFKNFMQLVRVVCFIQKEIAQL 133 Query: 365 EGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 +FGE++L+YN R A+V A L +++ F+ + Sbjct: 134 GKGDAFGEISLLYNSKRTATVIANERSDLIVLEKDAFQEYM 174 >UniRef50_Q2WA28 Cluster: CheY-like receiver; n=3; Magnetospirillum|Rep: CheY-like receiver - Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) Length = 328 Score = 45.6 bits (103), Expect = 7e-04 Identities = 27/68 (39%), Positives = 39/68 (57%), Gaps = 1/68 (1%) Frame = +2 Query: 233 KRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEG-SGSFGELALMYNM 409 K+ G+ V +GD GD YV+E+G + T + +KV+ G +G FGE+AL+ N Sbjct: 206 KKFHAGQIVFSEGDAGDMAYVVESGKVSIFKTVNG--QKVILGQIGPNGVFGEMALIDNE 263 Query: 410 PRAASVRA 433 PR AS A Sbjct: 264 PRMASAMA 271 >UniRef50_Q2G4A2 Cluster: Cyclic nucleotide-binding domain (CNMP-BD) protein; n=1; Novosphingobium aromaticivorans DSM 12444|Rep: Cyclic nucleotide-binding domain (CNMP-BD) protein - Novosphingobium aromaticivorans (strain DSM 12444) Length = 321 Score = 45.6 bits (103), Expect = 7e-04 Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 2/82 (2%) Frame = +2 Query: 248 GEYVIRQGDDGDNFYVIENGVFDV--LVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAA 421 GE + RQGD Y++ G+ ++ + GD+ V+ E GE AL+ + PR+A Sbjct: 34 GETLFRQGDPPSALYLVGEGLLEIETRLPGDEAA--VISRIEPGQMVGEFALLDDGPRSA 91 Query: 422 SVRAQTAGALWAMDRHTFRRIL 487 +VRA A A + + R FR +L Sbjct: 92 NVRAVDASAGFVIARDRFRALL 113 >UniRef50_Q1GTY7 Cluster: Transcriptional regulator, Crp/Fnr family; n=3; Sphingomonadaceae|Rep: Transcriptional regulator, Crp/Fnr family - Sphingopyxis alaskensis (Sphingomonas alaskensis) Length = 227 Score = 45.6 bits (103), Expect = 7e-04 Identities = 33/113 (29%), Positives = 52/113 (46%), Gaps = 1/113 (0%) Frame = +2 Query: 143 ARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDV- 319 ARLAE +F L + ++ + G+ ++ QGD GD ++ G V Sbjct: 4 ARLAELQSPDSIFSGLSVEDWAEITRRAVQVNFAKGKELLVQGDPGDMMLILTEGTARVS 63 Query: 320 LVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFR 478 ++T R E V+ E GE+AL+ R ASV A +AG+ + R+ R Sbjct: 64 MLTAGGR-EIVLAYAEPGAVLGEIALLDGGERTASVTATSAGSALQLGRNALR 115 >UniRef50_Q0EYN2 Cluster: Possible mechanosensitive ion channel; n=1; Mariprofundus ferrooxydans PV-1|Rep: Possible mechanosensitive ion channel - Mariprofundus ferrooxydans PV-1 Length = 156 Score = 45.6 bits (103), Expect = 7e-04 Identities = 27/100 (27%), Positives = 53/100 (53%) Frame = +2 Query: 197 QQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSG 376 QQ++ V+ A+ K+ G+ ++++G+ G Y++ +G D+ D +V+++ EGS Sbjct: 23 QQLEGVVRAVAIKK---GDTIVKEGEKGGILYLVRSGCVDIFQDLDGQVQRLAGLGEGS- 78 Query: 377 SFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKS 496 GE+ + A+V A ++ MDR F R++ S Sbjct: 79 MIGEVTFLSGELATATVVAAEDSIVYTMDRAGFARLMQTS 118 >UniRef50_A7BRS9 Cluster: Transcriptional Regulator, Crp/Fnr family; n=1; Beggiatoa sp. PS|Rep: Transcriptional Regulator, Crp/Fnr family - Beggiatoa sp. PS Length = 248 Score = 45.6 bits (103), Expect = 7e-04 Identities = 26/88 (29%), Positives = 45/88 (51%) Frame = +2 Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334 + ++ I LF L+ QQ Q+ M R E GEY+ + G ++F++++ G +L Sbjct: 14 QELQKIYLFSGLNDQQFTQIKQGMRPIRLEDGEYLFKHGQRAEHFFMLKEGYIKLLRLSL 73 Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRA 418 + EKV +F E A+M+ MP + Sbjct: 74 EGAEKVFEVVSPGQTFAE-AIMF-MPNS 99 >UniRef50_A6G7H5 Cluster: Serine/threonine-protein kinase; n=2; Plesiocystis pacifica SIR-1|Rep: Serine/threonine-protein kinase - Plesiocystis pacifica SIR-1 Length = 547 Score = 45.6 bits (103), Expect = 7e-04 Identities = 25/65 (38%), Positives = 38/65 (58%) Frame = +2 Query: 245 PGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAAS 424 PG+++IR+ + GD Y+I G +V + D R E + + G FGE A++ + PR AS Sbjct: 347 PGDWIIREDEVGDAAYIILTGSCEVFKSIDGRWESLRKLHAGE-VFGETAILASTPRTAS 405 Query: 425 VRAQT 439 V A T Sbjct: 406 VVALT 410 >UniRef50_A5UZM8 Cluster: Cyclic nucleotide-binding protein; n=3; Chloroflexaceae|Rep: Cyclic nucleotide-binding protein - Roseiflexus sp. RS-1 Length = 167 Score = 45.6 bits (103), Expect = 7e-04 Identities = 28/98 (28%), Positives = 45/98 (45%), Gaps = 4/98 (4%) Frame = +2 Query: 146 RLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV 325 R+ E +R + +F L ++ QV R+ + V +GD GD Y++ G V++ Sbjct: 4 RVLENLRKVEIFAGLSDDELMQVAGVCRAIRTPASQTVFNEGDTGDELYIVHEGTVRVMI 63 Query: 326 T---GDDRV-EKVVHTYEGSGSFGELALMYNMPRAASV 427 T D V ++T FGE AL+ R A+V Sbjct: 64 TTRLSDGTVAPSTINTLYPGQCFGEQALLGGAARTATV 101 >UniRef50_Q23DN4 Cluster: Cyclic nucleotide-binding domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 809 Score = 45.6 bits (103), Expect = 7e-04 Identities = 33/103 (32%), Positives = 54/103 (52%), Gaps = 1/103 (0%) Frame = +2 Query: 170 ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEK 349 I +F S+ + + +L + E+ +PGEYVIRQG G FY + +G+ + DD + Sbjct: 544 IEIFESISIKNFRDLLQSAKEEYYDPGEYVIRQGTIGTKFYFVMSGIVCIF---DD--AR 598 Query: 350 VVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTF 475 + + +GS FGE AL + R RA T L ++++ F Sbjct: 599 SLSRFCPTGSYFGETALKVDSTR----RAVTPCELLSLEKQDF 637 >UniRef50_A7SKJ5 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 2425 Score = 45.6 bits (103), Expect = 7e-04 Identities = 22/63 (34%), Positives = 35/63 (55%) Frame = +2 Query: 251 EYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVR 430 EY++RQG+ G Y I+ G +VL DR + FGE+++++N PR S+R Sbjct: 1760 EYIVRQGEIGHEMYFIQKGDVEVL----DRDGNALAVLGPGSFFGEVSVLFNTPRTTSIR 1815 Query: 431 AQT 439 +T Sbjct: 1816 TRT 1818 Score = 45.2 bits (102), Expect = 9e-04 Identities = 23/81 (28%), Positives = 47/81 (58%) Frame = +2 Query: 245 PGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAAS 424 P + ++++G+ G + I G ++ DD + + + EG FGE++L+YNM RA++ Sbjct: 743 PSQMIVKKGETGQSICYIHKGKAEIY--DDDDITQSIVLEEGY-IFGEVSLVYNMLRASN 799 Query: 425 VRAQTAGALWAMDRHTFRRIL 487 VRA + ++ ++R ++L Sbjct: 800 VRALSPCVVFILNRDDMNKVL 820 Score = 42.7 bits (96), Expect = 0.005 Identities = 29/121 (23%), Positives = 54/121 (44%) Frame = +2 Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 304 + D + +R + LF D ++Q+ +PG+Y++ GD G Y I Sbjct: 1204 QQDVCEQESTDILREVPLFIECDENFIKQLSLCTTSYIFKPGDYIVYAGDMGREMYCIRR 1263 Query: 305 GVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484 G ++L D+ ++VV T FGE+ L+ R +V+ +T + +H ++ Sbjct: 1264 GQVNIL--NDE--DEVVGTLGPGSFFGEIGLVCGESRVYTVQCKTYCQTLMLTKHDMDKV 1319 Query: 485 L 487 L Sbjct: 1320 L 1320 Score = 37.5 bits (83), Expect = 0.18 Identities = 22/80 (27%), Positives = 42/80 (52%) Frame = +2 Query: 251 EYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVR 430 +Y++ +GD G +I+ G +V +TG+D +V+ E +G+ L+ P ++R Sbjct: 2322 DYILHKGDIGQQLIIIKRGTAEV-ITGED--PEVILPLEEMSFYGDRYLLAPGPHLETLR 2378 Query: 431 AQTAGALWAMDRHTFRRILL 490 A T ++ ++R ILL Sbjct: 2379 AVTNVDVFILERSDLDEILL 2398 >UniRef50_A7RFM7 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 158 Score = 45.6 bits (103), Expect = 7e-04 Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 3/114 (2%) Frame = +2 Query: 158 AVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDD 337 A++ + F L + V + + + +++QG +NFY I +G V+ D Sbjct: 29 ALQTMSSFAELPLHMQESVCKVAWHQSLPANKIIVKQGHLAENFYFIMSGSVTVVSENDP 88 Query: 338 RVEKV---VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILL 490 +V V T SFG+LA++ N R A+V ++ L + R ++RI + Sbjct: 89 TSGQVFASVATLRRGASFGDLAILKNCTRTATVVSKVPIHLLVISREDYQRIFM 142 >UniRef50_UPI00006D001D Cluster: cation channel family protein; n=1; Tetrahymena thermophila SB210|Rep: cation channel family protein - Tetrahymena thermophila SB210 Length = 1201 Score = 45.2 bits (102), Expect = 9e-04 Identities = 25/103 (24%), Positives = 51/103 (49%), Gaps = 2/103 (1%) Frame = +2 Query: 173 LLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGD-NFYVIENGVFDVLVTGD-DRVE 346 L + ++ +++V+ M E P E + +Q D D + Y I++G ++ V + + + Sbjct: 696 LFMVNFQSKVIKEVVYLMEEIIVAPNEIIFKQNDSEDQSIYFIQSGDVEIFVADNLGQTQ 755 Query: 347 KVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTF 475 KV+ FGE++ +PR AS R+ ++ ++R F Sbjct: 756 KVLAQITSDSVFGEISFFSGLPRTASARSLNLSTIYKINRQKF 798 >UniRef50_Q89W82 Cluster: Bll0811 protein; n=3; Bradyrhizobium|Rep: Bll0811 protein - Bradyrhizobium japonicum Length = 738 Score = 45.2 bits (102), Expect = 9e-04 Identities = 22/91 (24%), Positives = 46/91 (50%) Frame = +2 Query: 242 EPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAA 421 E GE +++ GD D+ + I +G +++ + V + + GE+ L+ PR+A Sbjct: 623 EAGEIIVQAGDAADSMHFILDGRVGIMIPAEQNGMTRVRSLGRYTTIGEMGLVSQTPRSA 682 Query: 422 SVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 +++A+ L+ ++ H F I ++ RK Sbjct: 683 TIQAEVDSVLYVLNTHQFDAIRDEAPALSRK 713 >UniRef50_Q6ANR0 Cluster: Related to nitrogen assimilation regulatory protein; n=1; Desulfotalea psychrophila|Rep: Related to nitrogen assimilation regulatory protein - Desulfotalea psychrophila Length = 881 Score = 45.2 bits (102), Expect = 9e-04 Identities = 30/114 (26%), Positives = 51/114 (44%) Frame = +2 Query: 173 LLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKV 352 +LF+ L +++ + + + GEYV RQG D Y++ G +++ D Sbjct: 14 VLFQDLSPEEIGRCSEMAMVEIVPMGEYVYRQGGQTDLLYLVAVGEAELVFEFDTSSVSA 73 Query: 353 VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514 V G FGE AL+ P A +VRA L F+ +L ++ +R+ Sbjct: 74 VGRVGPGGHFGETALLTGKPHAVAVRALFDLVLLIFKGSFFKDLLERNQCVRRR 127 >UniRef50_Q5P0W6 Cluster: Transcriptional regulator, Dnr/Nnr type; n=2; Azoarcus|Rep: Transcriptional regulator, Dnr/Nnr type - Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) Length = 229 Score = 45.2 bits (102), Expect = 9e-04 Identities = 26/90 (28%), Positives = 40/90 (44%) Frame = +2 Query: 143 ARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL 322 A + +R I F L A + +V E+ E GE + ++GD F+ + +G + Sbjct: 6 ADIPTLLRQISFFSELSADDIDRVARYTRERTLEKGEVLFQRGDPVHGFFFVVSGQMKLA 65 Query: 323 VTGDDRVEKVVHTYEGSGSFGELALMYNMP 412 V+ EKVV SFGE + N P Sbjct: 66 VSSAQGNEKVVEIISPMNSFGEAVMFLNRP 95 >UniRef50_Q2S8X4 Cluster: CAMP-binding protein-catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; n=1; Hahella chejuensis KCTC 2396|Rep: CAMP-binding protein-catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase - Hahella chejuensis (strain KCTC 2396) Length = 263 Score = 45.2 bits (102), Expect = 9e-04 Identities = 28/80 (35%), Positives = 45/80 (56%) Frame = +2 Query: 236 RSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPR 415 R +PG+ +IRQG++ DN Y + G D V D+ ++V +EG FG +A + N PR Sbjct: 153 RYKPGDVIIRQGEEADNVYTMMKG--DAKVFIDE--QEVGEVHEGE-IFGAIAALTNAPR 207 Query: 416 AASVRAQTAGALWAMDRHTF 475 A+V A + + A+ + F Sbjct: 208 NATVVAGNSCTVMAVPKTQF 227 >UniRef50_Q1YDY1 Cluster: Putative cyclic nucleotide-binding protein; n=2; Aurantimonadaceae|Rep: Putative cyclic nucleotide-binding protein - Aurantimonas sp. SI85-9A1 Length = 151 Score = 45.2 bits (102), Expect = 9e-04 Identities = 34/109 (31%), Positives = 49/109 (44%) Frame = +2 Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340 +R + LF L A Q++ + +R E+V R+ D VI +G L+ G Sbjct: 10 LRNVPLFEDLHADQLRLLAFGAERRRLHRDEFVFREDARSDAGLVIVSGEI-ALLRGRPA 68 Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 + VV TY GE+AL+ R S R T L + R FRR+L Sbjct: 69 HQTVVGTYGPGTLLGEMALITETRRPTSARTLTDCELIRITRPLFRRML 117 >UniRef50_Q13J41 Cluster: Transcriptional regulator, Crp/Fnr family; n=5; Burkholderiaceae|Rep: Transcriptional regulator, Crp/Fnr family - Burkholderia xenovorans (strain LB400) Length = 237 Score = 45.2 bits (102), Expect = 9e-04 Identities = 29/114 (25%), Positives = 49/114 (42%) Frame = +2 Query: 146 RLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV 325 +LA + FRS A Q+++A +R G+ + +GD D Y + +G+ + Sbjct: 9 KLAAVLERSAWFRSAPATMQAQLVEAGRLERLAAGQRLFTRGDSDDGLYCVLDGLVRIGA 68 Query: 326 TGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487 E ++ E FGE+AL N PR A+ L+ + R +L Sbjct: 69 ASSAGKEALLAVIEPVNWFGEIALFDNRPRTHDAYAERDSELFHVPRAALAALL 122 >UniRef50_A0XC88 Cluster: Cyclic nucleotide-binding; n=1; Dinoroseobacter shibae DFL 12|Rep: Cyclic nucleotide-binding - Dinoroseobacter shibae DFL 12 Length = 733 Score = 45.2 bits (102), Expect = 9e-04 Identities = 29/93 (31%), Positives = 47/93 (50%), Gaps = 1/93 (1%) Frame = +2 Query: 191 DAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV-TGDDRVEKVVHTYE 367 DA Q+VL M + G+ ++ GD + ++E G VL T D R+ ++ Sbjct: 602 DAALAQRVLSMMTREEVAAGQRLMACGDRDTDVILVERGQLAVLAPTPDGRMRRIQSLRP 661 Query: 368 GSGSFGELALMYNMPRAASVRAQTAGALWAMDR 466 G+ GE+A +PRAA V A+TA ++ +R Sbjct: 662 GA-LIGEIASYAGLPRAADVIAETAATVYRFNR 693 >UniRef50_A7RK87 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 573 Score = 45.2 bits (102), Expect = 9e-04 Identities = 29/123 (23%), Positives = 59/123 (47%), Gaps = 1/123 (0%) Frame = +2 Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 304 +++ Q A++ ++R I F + ++++ + + ++RQG FY + + Sbjct: 165 RTEQQCAKVLFSLRSIRAFAEYPQRIQHKLINVGWYESHSSKRAILRQGQIPQAFYFVLS 224 Query: 305 GVFDVLVTGD-DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481 G V V G+ D + VH SFGELA++++ R ++V ++ L + R F Sbjct: 225 GSAVVTVLGEHDTFARTVHFLRRGDSFGELAILHDTQRQSTVISREPIELLVISREDFID 284 Query: 482 ILL 490 I + Sbjct: 285 IFM 287 >UniRef50_A0E001 Cluster: Chromosome undetermined scaffold_70, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_70, whole genome shotgun sequence - Paramecium tetraurelia Length = 467 Score = 45.2 bits (102), Expect = 9e-04 Identities = 31/95 (32%), Positives = 49/95 (51%), Gaps = 16/95 (16%) Frame = +2 Query: 248 GEYVIRQGDDGDNFYVIENG---VFDVLVTGD-------------DRVEKVVHTYEGSGS 379 GE + R+GD GD FY+I G V+ V + D+ K+ H EG + Sbjct: 67 GEIICREGDKGDKFYIILQGNVSVYRKNVNSNYEPNSVLSEQIFMDQNVKIGHLKEGE-T 125 Query: 380 FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484 FGELAL N PR A+++AQ+ L ++ + + ++ Sbjct: 126 FGELALSLNKPRFATIKAQSTVILCSLSKDNYAKM 160 >UniRef50_A0DVS8 Cluster: Chromosome undetermined scaffold_66, whole genome shotgun sequence; n=5; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_66, whole genome shotgun sequence - Paramecium tetraurelia Length = 637 Score = 45.2 bits (102), Expect = 9e-04 Identities = 26/66 (39%), Positives = 40/66 (60%), Gaps = 4/66 (6%) Frame = +2 Query: 248 GEYVIRQGDDGDNFYVIENGVFDV----LVTGDDRVEKVVHTYEGSGSFGELALMYNMPR 415 G+ + R+GD G FY+I G + LV + + ++++ +G G FGELAL N PR Sbjct: 106 GQTLFREGDVGTTFYIILQGRVSIHKRLLVQEEFQDKELIQLQDGQG-FGELALENNEPR 164 Query: 416 AASVRA 433 +ASV+A Sbjct: 165 SASVKA 170 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 545,932,510 Number of Sequences: 1657284 Number of extensions: 11821154 Number of successful extensions: 55057 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 50874 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 54721 length of database: 575,637,011 effective HSP length: 95 effective length of database: 418,195,031 effective search space used: 31782822356 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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