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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= epV30235
         (516 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q7PPI8 Cluster: ENSANGP00000022232; n=3; Endopterygota|...   239   3e-62
UniRef50_P81900 Cluster: cAMP-dependent protein kinase type II r...   232   3e-60
UniRef50_Q5DI18 Cluster: SJCHGC02266 protein; n=1; Schistosoma j...   192   5e-48
UniRef50_P31323 Cluster: cAMP-dependent protein kinase type II-b...   189   4e-47
UniRef50_Q4RSC3 Cluster: Chromosome 13 SCAF15000, whole genome s...   173   2e-42
UniRef50_P31320 Cluster: cAMP-dependent protein kinase regulator...   148   6e-35
UniRef50_A7RGJ3 Cluster: Predicted protein; n=1; Nematostella ve...   139   4e-32
UniRef50_A7S513 Cluster: Predicted protein; n=1; Nematostella ve...   132   5e-30
UniRef50_A6SCU8 Cluster: Putative uncharacterized protein; n=2; ...   132   6e-30
UniRef50_Q5H7P2 Cluster: CAMP-dependent protein kinase regulator...   131   8e-30
UniRef50_Q86ZN7 Cluster: cAMP-dependent protein kinase regulator...   130   2e-29
UniRef50_P10644 Cluster: cAMP-dependent protein kinase type I-al...   126   2e-28
UniRef50_Q4TGP1 Cluster: Chromosome undetermined SCAF3574, whole...   124   1e-27
UniRef50_P07278 Cluster: cAMP-dependent protein kinase regulator...   121   9e-27
UniRef50_Q9HEW1 Cluster: cAMP-dependent protein kinase regulator...   121   9e-27
UniRef50_Q9HFV9 Cluster: CAMP dependent protein kinase regulator...   120   2e-26
UniRef50_Q240X5 Cluster: Cyclic nucleotide-binding domain contai...   115   6e-25
UniRef50_Q5DAR5 Cluster: SJCHGC05163 protein; n=1; Schistosoma j...   113   2e-24
UniRef50_Q9BMY7 Cluster: CAMP-dependent protein kinase regulator...   111   7e-24
UniRef50_Q22NC5 Cluster: Cyclic nucleotide-binding domain contai...   111   7e-24
UniRef50_A0DZ01 Cluster: Chromosome undetermined scaffold_7, who...   111   9e-24
UniRef50_Q7KQK0 Cluster: CAMP-dependent protein kinase regulator...   109   3e-23
UniRef50_Q3SED2 Cluster: CAMP-dependent protein kinase, regulato...   109   4e-23
UniRef50_UPI0001509E09 Cluster: cyclic nucleotide-binding domain...   108   8e-23
UniRef50_P49605 Cluster: cAMP-dependent protein kinase regulator...   108   8e-23
UniRef50_P05987 Cluster: cAMP-dependent protein kinase regulator...   107   2e-22
UniRef50_Q6C2X0 Cluster: cAMP-dependent protein kinase regulator...   105   6e-22
UniRef50_Q9XTM6 Cluster: CAMP-dependent protein kinase regulator...   104   1e-21
UniRef50_A0CJF2 Cluster: Chromosome undetermined scaffold_2, who...   104   1e-21
UniRef50_A0BRC9 Cluster: Chromosome undetermined scaffold_122, w...   104   1e-21
UniRef50_Q8TF77 Cluster: cAMP-dependent protein kinase regulator...   104   1e-21
UniRef50_A0BNE3 Cluster: Chromosome undetermined scaffold_118, w...   103   2e-21
UniRef50_A2R984 Cluster: Catalytic activity: ATP + a protein <=>...   103   2e-21
UniRef50_Q4UEK0 Cluster: CAMP-dependent protein kinase regulator...   101   7e-21
UniRef50_A3FPL6 Cluster: CAMP-dependent protein kinase regulator...   100   2e-20
UniRef50_P36600 Cluster: cAMP-dependent protein kinase regulator...    99   5e-20
UniRef50_A7AU83 Cluster: cAMP-dependent protein kinase regulator...    99   7e-20
UniRef50_Q33DX2 Cluster: Putative cyclic AMP-dependent protein k...    69   2e-19
UniRef50_A0CMC2 Cluster: Chromosome undetermined scaffold_21, wh...    95   8e-19
UniRef50_UPI000065ED67 Cluster: cAMP-dependent protein kinase ty...    88   1e-16
UniRef50_UPI0000D562F1 Cluster: PREDICTED: similar to CG3324-PA;...    87   3e-16
UniRef50_Q8MQE4 Cluster: Putative uncharacterized protein; n=5; ...    85   1e-15
UniRef50_Q3SEP0 Cluster: CGMP-dependent protein kinase 8-2; n=8;...    84   2e-15
UniRef50_A0E3G7 Cluster: Chromosome undetermined scaffold_76, wh...    81   1e-14
UniRef50_Q13237 Cluster: cGMP-dependent protein kinase 2; n=23; ...    81   1e-14
UniRef50_Q03042 Cluster: cGMP-dependent protein kinase, isozyme ...    81   2e-14
UniRef50_Q16JU3 Cluster: Cgmp-dependent protein kinase; n=2; End...    78   1e-13
UniRef50_UPI0000DB6E55 Cluster: PREDICTED: similar to cGMP-depen...    77   2e-13
UniRef50_Q22SE3 Cluster: Cyclic nucleotide-binding domain contai...    76   4e-13
UniRef50_UPI0000519F68 Cluster: PREDICTED: similar to cGMP-depen...    76   6e-13
UniRef50_Q22RR1 Cluster: Protein kinase domain containing protei...    76   6e-13
UniRef50_Q9FXQ0 Cluster: Cyclic nucreotide dependent protein kin...    75   7e-13
UniRef50_Q234E6 Cluster: Protein kinase domain containing protei...    75   7e-13
UniRef50_A2EKL9 Cluster: Cyclic nucleotide-binding domain contai...    75   7e-13
UniRef50_A0D9C4 Cluster: Chromosome undetermined scaffold_42, wh...    75   1e-12
UniRef50_A0DCJ0 Cluster: Chromosome undetermined scaffold_45, wh...    73   3e-12
UniRef50_Q6P5T7 Cluster: PRKG1 protein; n=14; Euteleostomi|Rep: ...    73   3e-12
UniRef50_P14619 Cluster: cGMP-dependent protein kinase 1, beta i...    73   3e-12
UniRef50_Q31QH3 Cluster: Cyclic nucleotide-binding; n=2; Synecho...    73   4e-12
UniRef50_Q5RGL5 Cluster: Novel protein similar to vertebrate pro...    73   5e-12
UniRef50_Q8MMZ4 Cluster: CGMP-dependent protein kinase; n=14; Ap...    72   9e-12
UniRef50_Q5CWD4 Cluster: Cyclic nucleotide (CGMP)-dependent prot...    72   9e-12
UniRef50_A7PEK0 Cluster: Chromosome chr11 scaffold_13, whole gen...    71   2e-11
UniRef50_Q9VL34 Cluster: CG4839-PA, isoform A; n=2; Sophophora|R...    69   5e-11
UniRef50_O76360 Cluster: Egg laying defective protein 4, isoform...    69   6e-11
UniRef50_O17474 Cluster: Cyclic GMP-dependent protein kinase; n=...    69   6e-11
UniRef50_A7C1J1 Cluster: Protein kinase, cGMP-dependent, type I;...    69   8e-11
UniRef50_Q4QGD8 Cluster: Protein kinase A regulatory subunit, pu...    69   8e-11
UniRef50_Q23DN8 Cluster: Cyclic nucleotide-binding domain contai...    68   1e-10
UniRef50_Q4QF64 Cluster: Protein kinase, putative; n=2; Leishman...    68   1e-10
UniRef50_A0BE58 Cluster: Chromosome undetermined scaffold_101, w...    67   3e-10
UniRef50_A4S6U9 Cluster: Predicted protein; n=2; Ostreococcus|Re...    66   4e-10
UniRef50_Q01E02 Cluster: CGMP-dependent protein kinase, putative...    61   5e-10
UniRef50_Q8MMZ5 Cluster: CGMP-dependent protein kinase; n=2; Eim...    66   6e-10
UniRef50_Q4Q2R2 Cluster: Regulatory subunit of protein kinase a-...    65   8e-10
UniRef50_A0E0G1 Cluster: Chromosome undetermined scaffold_71, wh...    64   2e-09
UniRef50_Q2HGG6 Cluster: Putative uncharacterized protein; n=1; ...    64   2e-09
UniRef50_A0YP22 Cluster: Putative uncharacterized protein; n=1; ...    63   3e-09
UniRef50_Q4CSS9 Cluster: Protein kinase, putative; n=2; Trypanos...    62   6e-09
UniRef50_Q0LLK2 Cluster: Stage II sporulation E; n=1; Herpetosip...    62   7e-09
UniRef50_UPI0000660D74 Cluster: Homolog of Homo sapiens "cGMP-de...    62   1e-08
UniRef50_Q8DKN0 Cluster: Tlr0829 protein; n=1; Synechococcus elo...    62   1e-08
UniRef50_A5GVU5 Cluster: ABC-type multidrug transport system, AT...    62   1e-08
UniRef50_A3IKE0 Cluster: Putative uncharacterized protein; n=1; ...    62   1e-08
UniRef50_Q4SL71 Cluster: Chromosome 17 SCAF14563, whole genome s...    59   1e-08
UniRef50_Q8SRB5 Cluster: CAMP-DEPENDENT PROTEIN KINASE TYPE 1 RE...    61   1e-08
UniRef50_Q1D8K7 Cluster: Mechanosensitive ion channel/cyclic nuc...    61   2e-08
UniRef50_A4TWF8 Cluster: Na+/H+ Antiporter; n=1; Magnetospirillu...    61   2e-08
UniRef50_Q9M8S6 Cluster: Potassium channel SKOR (Stelar K(+) out...    59   5e-08
UniRef50_Q8CXT1 Cluster: CAMP-dependent protein kinase regulator...    59   7e-08
UniRef50_Q2VWB6 Cluster: CAMP-dependent protein kinase A regulat...    59   7e-08
UniRef50_Q5QFC4 Cluster: EnvDll2-01; n=1; Oikopleura dioica|Rep:...    58   9e-08
UniRef50_A7C147 Cluster: cGMP-dependent protein kinase type I; n...    58   1e-07
UniRef50_A3YU60 Cluster: Putative glutaminase; n=1; Synechococcu...    58   2e-07
UniRef50_Q10V66 Cluster: Cyclic nucleotide-binding protein; n=2;...    57   2e-07
UniRef50_Q9Y3Q4 Cluster: Potassium/sodium hyperpolarization-acti...    57   2e-07
UniRef50_Q4S874 Cluster: Chromosome 5 SCAF14709, whole genome sh...    57   3e-07
UniRef50_Q3W7N0 Cluster: Cyclic nucleotide-binding domain:Peptid...    57   3e-07
UniRef50_Q0VQV6 Cluster: Cyclic nucleotide-binding domain protei...    57   3e-07
UniRef50_UPI0000EC9F34 Cluster: UPI0000EC9F34 related cluster; n...    56   4e-07
UniRef50_Q6WL05 Cluster: Hyperpolarization-activated ion channel...    56   4e-07
UniRef50_A5G0B9 Cluster: Putative transcriptional regulator, Crp...    56   5e-07
UniRef50_A0LNC0 Cluster: Cyclic nucleotide-binding protein; n=1;...    56   5e-07
UniRef50_Q23EB7 Cluster: Cyclic nucleotide-binding domain contai...    56   5e-07
UniRef50_Q2LV90 Cluster: CAMP-dependent transcriptional regulato...    56   6e-07
UniRef50_Q0F2T2 Cluster: Glucose-6-phosphate 1-dehydrogenase; n=...    56   6e-07
UniRef50_Q08V69 Cluster: PKA regulatory subunit-like protein; n=...    56   6e-07
UniRef50_A7BXC8 Cluster: MscS Mechanosensitive ion channel; n=1;...    56   6e-07
UniRef50_Q2RX44 Cluster: Cyclic nucleotide-binding domain (CNMP-...    55   8e-07
UniRef50_Q695H0 Cluster: CGMP-dependent protein kinase; n=1; Chl...    55   8e-07
UniRef50_UPI0000383B9A Cluster: COG0642: Signal transduction his...    55   1e-06
UniRef50_Q4RR21 Cluster: Chromosome 14 SCAF15003, whole genome s...    55   1e-06
UniRef50_Q2S6T5 Cluster: CAMP-binding protein-catabolite gene ac...    55   1e-06
UniRef50_A0DBC7 Cluster: Chromosome undetermined scaffold_44, wh...    55   1e-06
UniRef50_Q09BB2 Cluster: Cyclic nucleotide-binding:Bacterial reg...    54   1e-06
UniRef50_A0YAY7 Cluster: CAMP-binding protein-catabolite gene ac...    54   1e-06
UniRef50_A0GWU5 Cluster: Stage II sporulation E; n=2; Chloroflex...    54   1e-06
UniRef50_Q3MD80 Cluster: Cyclic nucleotide-binding domain (CNMP-...    54   2e-06
UniRef50_Q5WUW4 Cluster: Putative uncharacterized protein; n=4; ...    54   3e-06
UniRef50_P74736 Cluster: CAMP protein kinase regulatory chain; n...    54   3e-06
UniRef50_A5UY70 Cluster: Cyclic nucleotide-binding protein; n=3;...    54   3e-06
UniRef50_A5PH37 Cluster: AKT2 inward rectifier channel; n=6; Emb...    54   3e-06
UniRef50_O76977 Cluster: Hyperpolarization-activated (Ih) channe...    54   3e-06
UniRef50_A0DKC6 Cluster: Chromosome undetermined scaffold_54, wh...    54   3e-06
UniRef50_A1Z9N7 Cluster: CG8585-PE, isoform E; n=18; Pancrustace...    53   3e-06
UniRef50_UPI000038CAE8 Cluster: COG1252: NADH dehydrogenase, FAD...    53   4e-06
UniRef50_A0DG99 Cluster: Chromosome undetermined scaffold_5, who...    53   4e-06
UniRef50_Q3AAI0 Cluster: CBS/cyclic nucleotide-binding domain pr...    52   6e-06
UniRef50_A7SE96 Cluster: Predicted protein; n=1; Nematostella ve...    52   6e-06
UniRef50_A0DXZ3 Cluster: Chromosome undetermined scaffold_69, wh...    52   6e-06
UniRef50_P74608 Cluster: Slr1575 protein; n=1; Synechocystis sp....    52   8e-06
UniRef50_Q2ADG0 Cluster: Cyclic nucleotide-binding:Bacterial reg...    52   8e-06
UniRef50_Q7UTR3 Cluster: ATP-binding subunit of ABC transporter;...    52   1e-05
UniRef50_Q46TY3 Cluster: Cyclic nucleotide-binding; n=2; Cupriav...    52   1e-05
UniRef50_Q1D9I5 Cluster: PBS lyase HEAT-like repeat/cyclic nucle...    52   1e-05
UniRef50_Q8ILS1 Cluster: Putative uncharacterized protein; n=1; ...    52   1e-05
UniRef50_Q7RDH4 Cluster: Reticulocyte-binding protein 2 homolog ...    52   1e-05
UniRef50_UPI00006CA698 Cluster: cation channel family protein; n...    51   1e-05
UniRef50_Q09BB3 Cluster: PKA regulatory subunit-like protein; n=...    51   1e-05
UniRef50_A0YLS1 Cluster: Putative uncharacterized protein; n=1; ...    51   1e-05
UniRef50_Q7K3Z6 Cluster: GH01501p; n=4; Diptera|Rep: GH01501p - ...    51   1e-05
UniRef50_Q23EB4 Cluster: ABC transporter family protein; n=3; Te...    51   1e-05
UniRef50_Q4WI41 Cluster: Cyclic nucleotide-binding domain protei...    51   1e-05
UniRef50_A1CZ15 Cluster: Cyclic nucleotide-binding domain protei...    51   1e-05
UniRef50_UPI000038CAE7 Cluster: COG1012: NAD-dependent aldehyde ...    51   2e-05
UniRef50_Q6MJQ6 Cluster: Hyperpolarization-activated, cyclic nuc...    51   2e-05
UniRef50_A3YU63 Cluster: Possible mechanosensitive ion channel; ...    51   2e-05
UniRef50_A3EYY6 Cluster: Tetrameric potassium-selective cyclic n...    51   2e-05
UniRef50_Q10898 Cluster: Uncharacterized protein Rv0104/MT0113; ...    51   2e-05
UniRef50_UPI00006D001F Cluster: cyclic nucleotide-binding domain...    50   2e-05
UniRef50_Q131K0 Cluster: Cyclic nucleotide-binding precursor; n=...    50   2e-05
UniRef50_Q5CD46 Cluster: PKA regulatory subunit homologous prote...    50   2e-05
UniRef50_A6G0I3 Cluster: Putative uncharacterized protein; n=1; ...    50   2e-05
UniRef50_UPI00006CA699 Cluster: cyclic nucleotide-binding domain...    50   3e-05
UniRef50_UPI000065D7C1 Cluster: Homolog of Oncorhynchus mykiss "...    50   3e-05
UniRef50_Q98GM7 Cluster: Mlr3256 protein; n=2; Alphaproteobacter...    50   3e-05
UniRef50_Q2LPZ1 Cluster: Cyclic nucleotide-binding domain protei...    50   3e-05
UniRef50_Q1D5Q4 Cluster: Cyclic nucleotide-binding domain protei...    50   3e-05
UniRef50_Q08NQ8 Cluster: Protein phosphatase 1; n=2; Cystobacter...    50   4e-05
UniRef50_A0YM45 Cluster: Sulfate transporter family protein; n=1...    50   4e-05
UniRef50_Q23WN2 Cluster: Cyclic nucleotide-binding domain contai...    50   4e-05
UniRef50_P63401 Cluster: Uncharacterized ABC transporter ATP-bin...    50   4e-05
UniRef50_UPI00006CC0E9 Cluster: cation channel family protein; n...    49   6e-05
UniRef50_Q2YZI3 Cluster: Putative uncharacterized protein; n=1; ...    49   6e-05
UniRef50_Q1PUQ2 Cluster: Similar to transcriptional regulator of...    49   6e-05
UniRef50_A4M043 Cluster: Transcriptional regulator, Crp/Fnr fami...    49   6e-05
UniRef50_Q4D6P2 Cluster: Regulatory subunit of protein kinase a-...    49   6e-05
UniRef50_Q22R60 Cluster: Cyclic nucleotide-binding domain contai...    49   6e-05
UniRef50_Q8WZA2 Cluster: Rap guanine nucleotide exchange factor ...    49   6e-05
UniRef50_Q9P1Z3 Cluster: Potassium/sodium hyperpolarization-acti...    49   6e-05
UniRef50_Q1GWA6 Cluster: Cyclic nucleotide-binding protein precu...    49   7e-05
UniRef50_Q0VMY3 Cluster: CAMP-dependent protein kinase regulator...    49   7e-05
UniRef50_A0YHV0 Cluster: Putative uncharacterized protein; n=1; ...    49   7e-05
UniRef50_Q00X68 Cluster: Cyclic nucleotide dependent protein kin...    49   7e-05
UniRef50_A4RUE3 Cluster: Predicted protein; n=1; Ostreococcus lu...    49   7e-05
UniRef50_Q23EB1 Cluster: Cation channel family protein; n=2; Tet...    49   7e-05
UniRef50_UPI00006CF9CA Cluster: cation channel family protein; n...    48   1e-04
UniRef50_UPI00006A1C4D Cluster: Uncharacterized protein C20orf15...    48   1e-04
UniRef50_UPI0000EC9E1A Cluster: Rap guanine nucleotide exchange ...    48   1e-04
UniRef50_Q1DAY2 Cluster: Cyclic nucleotide-binding domain protei...    48   1e-04
UniRef50_A6G5Y4 Cluster: Protein phosphatase/cyclic nucleotide-b...    48   1e-04
UniRef50_A0YCM5 Cluster: CAMP-binding protein-catabolite gene ac...    48   1e-04
UniRef50_Q9NQW8 Cluster: Cyclic nucleotide-gated cation channel ...    48   1e-04
UniRef50_Q2SDD5 Cluster: CAMP-binding protein-catabolite gene ac...    48   1e-04
UniRef50_Q08UL3 Cluster: TrkA-N domain family; n=1; Stigmatella ...    48   1e-04
UniRef50_A0LIE9 Cluster: Cyclic nucleotide-binding protein; n=1;...    48   1e-04
UniRef50_Q23EB3 Cluster: Cyclic nucleotide-binding domain contai...    48   1e-04
UniRef50_A7SFW1 Cluster: Predicted protein; n=1; Nematostella ve...    48   1e-04
UniRef50_UPI0000F1F638 Cluster: PREDICTED: similar to putative c...    48   2e-04
UniRef50_UPI00006CFEF7 Cluster: cation channel family protein; n...    48   2e-04
UniRef50_Q5NXU3 Cluster: Catabolite gene activator; n=3; Rhodocy...    48   2e-04
UniRef50_Q2RK98 Cluster: Transcriptional regulator, Crp/Fnr fami...    48   2e-04
UniRef50_Q935V9 Cluster: Transcriptional regulator with cyclic n...    48   2e-04
UniRef50_Q7D4Z5 Cluster: Drug transporter; n=19; Mycobacterium|R...    48   2e-04
UniRef50_Q05VE2 Cluster: Possible mechanosensitive ion channel; ...    48   2e-04
UniRef50_A6GAV1 Cluster: Protein phosphatase/cyclic nucleotide-b...    48   2e-04
UniRef50_A0P0J2 Cluster: Putative catabolite gene activator; n=2...    48   2e-04
UniRef50_Q45ZY2 Cluster: Hyperpolarization-gated and cyclic nucl...    48   2e-04
UniRef50_Q24DS4 Cluster: Cation channel family protein; n=1; Tet...    48   2e-04
UniRef50_Q59V20 Cluster: Putative uncharacterized protein; n=1; ...    48   2e-04
UniRef50_Q8XR93 Cluster: Probable transcription regulator protei...    47   2e-04
UniRef50_Q2K3Q8 Cluster: Probable cation transporter protein; n=...    47   2e-04
UniRef50_Q1NMR4 Cluster: Cyclic nucleotide-binding; n=2; delta p...    47   2e-04
UniRef50_Q0LJ13 Cluster: Cyclic nucleotide-binding; n=2; Chlorof...    47   2e-04
UniRef50_A4XWI5 Cluster: Cyclic nucleotide-binding protein; n=2;...    47   2e-04
UniRef50_A1ZHX6 Cluster: Serine/threonine protein kinases; n=1; ...    47   2e-04
UniRef50_A0L6N5 Cluster: Cyclic nucleotide-binding; n=1; Magneto...    47   2e-04
UniRef50_Q554K9 Cluster: CGMP-stimulated cGMP phosphodiesterase;...    47   2e-04
UniRef50_A0CLY8 Cluster: Chromosome undetermined scaffold_21, wh...    47   2e-04
UniRef50_O95398 Cluster: Rap guanine nucleotide exchange factor ...    47   2e-04
UniRef50_Q7V424 Cluster: Possible mechanosensitive ion channel; ...    47   3e-04
UniRef50_Q9X7J4 Cluster: DnrD protein; n=9; Pseudomonas|Rep: Dnr...    47   3e-04
UniRef50_Q1YDI6 Cluster: Possible cAMP-dependent regulatory prot...    47   3e-04
UniRef50_A7SKJ9 Cluster: Predicted protein; n=1; Nematostella ve...    47   3e-04
UniRef50_P34578 Cluster: Uncharacterized protein T20G5.5; n=2; C...    47   3e-04
UniRef50_UPI000065E24B Cluster: Rap guanine nucleotide exchange ...    46   4e-04
UniRef50_Q92SD2 Cluster: PUTATIVE TRANSCRIPTION REGULATOR PROTEI...    46   4e-04
UniRef50_Q30Y06 Cluster: Transcriptional regulator, Crp/Fnr fami...    46   4e-04
UniRef50_Q7CWQ8 Cluster: AGR_C_4670p; n=6; Rhizobiaceae|Rep: AGR...    46   4e-04
UniRef50_Q236Y9 Cluster: Cyclic nucleotide-binding domain contai...    46   4e-04
UniRef50_A0CY63 Cluster: Chromosome undetermined scaffold_301, w...    46   4e-04
UniRef50_P0A642 Cluster: Uncharacterized NTE family protein Rv25...    46   4e-04
UniRef50_UPI00015BC926 Cluster: UPI00015BC926 related cluster; n...    46   5e-04
UniRef50_UPI00006CE543 Cluster: cyclic nucleotide-binding domain...    46   5e-04
UniRef50_UPI00006CB774 Cluster: cyclic nucleotide-binding domain...    46   5e-04
UniRef50_Q2W0I8 Cluster: Kef-type K+ transport systems, predicte...    46   5e-04
UniRef50_Q0VS63 Cluster: Cyclic nucleotide-binding protein; n=1;...    46   5e-04
UniRef50_A0E9X9 Cluster: Chromosome undetermined scaffold_85, wh...    46   5e-04
UniRef50_A0CUC4 Cluster: Chromosome undetermined scaffold_28, wh...    46   5e-04
UniRef50_Q2WA28 Cluster: CheY-like receiver; n=3; Magnetospirill...    46   7e-04
UniRef50_Q2G4A2 Cluster: Cyclic nucleotide-binding domain (CNMP-...    46   7e-04
UniRef50_Q1GTY7 Cluster: Transcriptional regulator, Crp/Fnr fami...    46   7e-04
UniRef50_Q0EYN2 Cluster: Possible mechanosensitive ion channel; ...    46   7e-04
UniRef50_A7BRS9 Cluster: Transcriptional Regulator, Crp/Fnr fami...    46   7e-04
UniRef50_A6G7H5 Cluster: Serine/threonine-protein kinase; n=2; P...    46   7e-04
UniRef50_A5UZM8 Cluster: Cyclic nucleotide-binding protein; n=3;...    46   7e-04
UniRef50_Q23DN4 Cluster: Cyclic nucleotide-binding domain contai...    46   7e-04
UniRef50_A7SKJ5 Cluster: Predicted protein; n=2; Nematostella ve...    46   7e-04
UniRef50_A7RFM7 Cluster: Predicted protein; n=1; Nematostella ve...    46   7e-04
UniRef50_UPI00006D001D Cluster: cation channel family protein; n...    45   9e-04
UniRef50_Q89W82 Cluster: Bll0811 protein; n=3; Bradyrhizobium|Re...    45   9e-04
UniRef50_Q6ANR0 Cluster: Related to nitrogen assimilation regula...    45   9e-04
UniRef50_Q5P0W6 Cluster: Transcriptional regulator, Dnr/Nnr type...    45   9e-04
UniRef50_Q2S8X4 Cluster: CAMP-binding protein-catabolite gene ac...    45   9e-04
UniRef50_Q1YDY1 Cluster: Putative cyclic nucleotide-binding prot...    45   9e-04
UniRef50_Q13J41 Cluster: Transcriptional regulator, Crp/Fnr fami...    45   9e-04
UniRef50_A0XC88 Cluster: Cyclic nucleotide-binding; n=1; Dinoros...    45   9e-04
UniRef50_A7RK87 Cluster: Predicted protein; n=1; Nematostella ve...    45   9e-04
UniRef50_A0E001 Cluster: Chromosome undetermined scaffold_70, wh...    45   9e-04
UniRef50_A0DVS8 Cluster: Chromosome undetermined scaffold_66, wh...    45   9e-04
UniRef50_A0DME6 Cluster: Chromosome undetermined scaffold_56, wh...    45   9e-04
UniRef50_A0DFJ4 Cluster: Chromosome undetermined scaffold_49, wh...    45   9e-04
UniRef50_Q6C384 Cluster: Similar to DEHA0B08261g Debaryomyces ha...    45   9e-04
UniRef50_Q8CXU7 Cluster: CAMP-dependent protein kinase regulator...    45   0.001
UniRef50_Q82V15 Cluster: Cyclic nucleotide-binding domain:cAMP-d...    45   0.001
UniRef50_Q746U7 Cluster: Transcriptional regulator, Crp/Fnr fami...    45   0.001
UniRef50_Q1IHC1 Cluster: Cyclic nucleotide-binding protein; n=1;...    45   0.001
UniRef50_Q0F204 Cluster: Cyclic nucleotide-binding protein; n=1;...    45   0.001
UniRef50_A1ZG79 Cluster: Transporter, small conductance mechanos...    45   0.001
UniRef50_UPI0000D56485 Cluster: PREDICTED: similar to Potassium/...    44   0.002
UniRef50_UPI0000384142 Cluster: COG2199: FOG: GGDEF domain; n=1;...    44   0.002
UniRef50_Q72T22 Cluster: Cyclic nucleotide binding patatin-like ...    44   0.002
UniRef50_Q7D903 Cluster: Cyclic nucleotide-binding protein; n=19...    44   0.002
UniRef50_A7BVI5 Cluster: Reductase; n=1; Beggiatoa sp. PS|Rep: R...    44   0.002
UniRef50_A6G6N1 Cluster: Cyclic nucleotide-binding domain protei...    44   0.002
UniRef50_A1IBE9 Cluster: Putative transcriptional regulator, Crp...    44   0.002
UniRef50_A0NZP6 Cluster: CAAX amino terminal protease family pro...    44   0.002
UniRef50_A0LQJ1 Cluster: Cyclic nucleotide-binding protein; n=1;...    44   0.002
UniRef50_Q23AA7 Cluster: Cation channel family protein; n=1; Tet...    44   0.002
UniRef50_Q23AA4 Cluster: Cation channel family protein; n=1; Tet...    44   0.002
UniRef50_Q22BB2 Cluster: Cyclic nucleotide-binding domain contai...    44   0.002
UniRef50_A5K155 Cluster: Putative uncharacterized protein; n=4; ...    44   0.002
UniRef50_A0BGA2 Cluster: Chromosome undetermined scaffold_105, w...    44   0.002
UniRef50_Q4SKD5 Cluster: Chromosome 13 SCAF14566, whole genome s...    44   0.002
UniRef50_Q89HD2 Cluster: Bll6060 protein; n=3; Bradyrhizobium|Re...    44   0.002
UniRef50_Q7MRZ8 Cluster: DNR; n=1; Wolinella succinogenes|Rep: D...    44   0.002
UniRef50_Q6MLN6 Cluster: Putative uncharacterized protein; n=1; ...    44   0.002
UniRef50_Q47A56 Cluster: Cyclic nucleotide-binding; n=1; Dechlor...    44   0.002
UniRef50_Q3JAP3 Cluster: Cyclic nucleotide-binding protein; n=1;...    44   0.002
UniRef50_Q0LIK4 Cluster: MscS Mechanosensitive ion channel; n=1;...    44   0.002
UniRef50_A4TXU7 Cluster: cAMP-binding protein-catabolite gene ac...    44   0.002
UniRef50_Q237N2 Cluster: Cation channel family protein; n=1; Tet...    44   0.002
UniRef50_A0E296 Cluster: Chromosome undetermined scaffold_74, wh...    44   0.002
UniRef50_Q64359 Cluster: Cyclic nucleotide-gated olfactory chann...    44   0.002
UniRef50_Q1LXY6 Cluster: Novel protein similar to vertebrate cyc...    44   0.003
UniRef50_Q3AF29 Cluster: Transcriptional regulator, Crp/Fnr fami...    44   0.003
UniRef50_Q1N3Q3 Cluster: Putative uncharacterized protein; n=1; ...    44   0.003
UniRef50_Q1D8V4 Cluster: Cyclic nucleotide-binding domain protei...    44   0.003
UniRef50_Q15QG5 Cluster: Transcriptional regulator, Crp/Fnr fami...    44   0.003
UniRef50_A4TW60 Cluster: cAMP-binding protein-catabolite gene ac...    44   0.003
UniRef50_Q22TN5 Cluster: Cation channel family protein; n=2; Tet...    44   0.003
UniRef50_A7SLM9 Cluster: Predicted protein; n=2; Nematostella ve...    44   0.003
UniRef50_A3LZH5 Cluster: Leucine rich repeat protein, contains F...    44   0.003
UniRef50_UPI00006CE52D Cluster: cyclic nucleotide-binding domain...    43   0.004
UniRef50_Q3I0N1 Cluster: Cyclic nucleotide-gated channel beta co...    43   0.004
UniRef50_Q97TL8 Cluster: CRP (Cyclic AMP receptor protein) regul...    43   0.004
UniRef50_Q6N2Q3 Cluster: Probable transcriptional regulator, Crp...    43   0.004
UniRef50_Q31NU6 Cluster: Cyclic nucleotide-binding domain (CNMP-...    43   0.004
UniRef50_A4LZF2 Cluster: Cyclic nucleotide-binding protein; n=2;...    43   0.004
UniRef50_Q23CM4 Cluster: Cyclic nucleotide-binding domain contai...    43   0.004
UniRef50_UPI0001509BB1 Cluster: cyclic nucleotide-binding domain...    43   0.005
UniRef50_Q9CS95 Cluster: 8 days embryo whole body cDNA, RIKEN fu...    43   0.005
UniRef50_Q1EMI3 Cluster: Putative ABC-type transport system, ATP...    43   0.005
UniRef50_Q1D9D3 Cluster: Cyclic nucleotide-binding domain protei...    43   0.005
UniRef50_Q18WV6 Cluster: Transcriptional regulator, Crp/Fnr fami...    43   0.005
UniRef50_A7BRE2 Cluster: Protein kinase, cGMP-dependent, type I;...    43   0.005
UniRef50_A5GPF7 Cluster: Conserved hyppthetical protein; n=1; Sy...    43   0.005
UniRef50_A4U0N5 Cluster: Transcriptional regulator, Crp/Fnr fami...    43   0.005
UniRef50_A2SMH7 Cluster: CAMP-dependent protein kinase-catabolit...    43   0.005
UniRef50_A0NR38 Cluster: Putative Na+/H+ antiporter with cyclic ...    43   0.005
UniRef50_Q23S28 Cluster: Cyclic nucleotide-binding domain contai...    43   0.005
UniRef50_Q03611 Cluster: Cyclic nucleotide-gated cation channel;...    43   0.005
UniRef50_UPI000155D050 Cluster: PREDICTED: similar to Cyclic nuc...    42   0.006
UniRef50_UPI0000F1EF31 Cluster: PREDICTED: similar to cyclic nuc...    42   0.006
UniRef50_UPI00006CFEE1 Cluster: cyclic nucleotide-binding domain...    42   0.006
UniRef50_Q55427 Cluster: Slr0842 protein; n=1; Synechocystis sp....    42   0.006
UniRef50_P74678 Cluster: DNR protein; n=1; Synechocystis sp. PCC...    42   0.006
UniRef50_A4J9H6 Cluster: Putative transcriptional regulator, Crp...    42   0.006
UniRef50_Q06XL5 Cluster: Inwardly rectifying potassium channel A...    42   0.006
UniRef50_P90975 Cluster: Cyclic nucleotide-gated channel; n=3; C...    42   0.006
UniRef50_A0DV12 Cluster: Chromosome undetermined scaffold_65, wh...    42   0.006
UniRef50_Q4RYB3 Cluster: Chromosome 3 SCAF14978, whole genome sh...    42   0.008
UniRef50_Q8EY25 Cluster: Cyclic nucleotide dependent protein kin...    42   0.008
UniRef50_Q7MBF0 Cluster: Probable transcriptional regulator, Crp...    42   0.008
UniRef50_Q2W4U7 Cluster: CAMP-binding protein-catabolite gene ac...    42   0.008
UniRef50_Q2J6W1 Cluster: Transcriptional regulator, Crp/Fnr fami...    42   0.008
UniRef50_Q1ETT3 Cluster: Cyclic nucleotide-binding:regulatory pr...    42   0.008
UniRef50_Q04S82 Cluster: CAMP-dependent protein kinase; n=4; Lep...    42   0.008
UniRef50_A5U333 Cluster: Crp/Fnr family transcriptional regulato...    42   0.008
UniRef50_A4BIJ9 Cluster: Transcriptional regulator Dnr; n=1; Rei...    42   0.008
UniRef50_A3YVU5 Cluster: Cyclic nucleotide-binding domain (CNMP-...    42   0.008
UniRef50_A1IEY7 Cluster: Putative transcriptional regulator, Crp...    42   0.008
UniRef50_A0NP85 Cluster: Cyclic nucleotide-binding domain (CNMP-...    42   0.008
UniRef50_Q23AA8 Cluster: Cation channel family protein; n=1; Tet...    42   0.008
UniRef50_Q14028 Cluster: Cyclic nucleotide-gated cation channel ...    42   0.008
UniRef50_UPI00006CC101 Cluster: cyclic nucleotide-binding domain...    42   0.011
UniRef50_Q9ER33 Cluster: Cyclic nucleotide-gated channel 2b; n=9...    42   0.011
UniRef50_Q8YY17 Cluster: Transcriptional regulator; n=6; Cyanoba...    42   0.011
UniRef50_Q315Y2 Cluster: Cyclic nucleotide-binding domain (CNMP-...    42   0.011
UniRef50_Q2S0L0 Cluster: Transcription regulator, Crp family, pu...    42   0.011
UniRef50_Q2AEB9 Cluster: Cyclic nucleotide-binding:Bacterial reg...    42   0.011
UniRef50_Q0K1D5 Cluster: Transcriptional regulator CRP family; n...    42   0.011
UniRef50_A5NZN3 Cluster: Cyclic nucleotide-binding protein; n=1;...    42   0.011
UniRef50_Q9LKP2 Cluster: Putative potassium channel protein Kmt1...    42   0.011
UniRef50_Q93486 Cluster: Putative uncharacterized protein cng-1;...    42   0.011
UniRef50_Q16281 Cluster: Cyclic nucleotide-gated cation channel ...    42   0.011
UniRef50_UPI00005890C6 Cluster: PREDICTED: similar to 240K prote...    41   0.015
UniRef50_Q3M891 Cluster: Transcriptional Regulator, Crp/Fnr fami...    41   0.015
UniRef50_Q2JXE2 Cluster: Cyclic nucleotide-binding protein, trun...    41   0.015
UniRef50_Q0EX27 Cluster: Cyclic nucleotide-binding:Bacterial reg...    41   0.015
UniRef50_Q01YJ3 Cluster: Cyclic nucleotide-binding protein precu...    41   0.015
UniRef50_A7HSM8 Cluster: Cyclic nucleotide-binding protein; n=1;...    41   0.015
UniRef50_A5UY24 Cluster: Cyclic nucleotide-binding protein; n=2;...    41   0.015
UniRef50_A1B7P5 Cluster: Putative transcriptional regulator, Crp...    41   0.015
UniRef50_A4S699 Cluster: Predicted protein; n=2; Ostreococcus|Re...    41   0.015
UniRef50_Q23YQ2 Cluster: Cyclic nucleotide-binding domain contai...    41   0.015
UniRef50_Q23R10 Cluster: Cation channel family protein; n=1; Tet...    41   0.015
UniRef50_Q236Y8 Cluster: Cyclic nucleotide-binding domain contai...    41   0.015
UniRef50_A0CUS7 Cluster: Chromosome undetermined scaffold_28, wh...    41   0.015
UniRef50_A0CB28 Cluster: Chromosome undetermined scaffold_163, w...    41   0.015
UniRef50_UPI00006CC00D Cluster: hypothetical protein TTHERM_0041...    41   0.019
UniRef50_UPI00006CA695 Cluster: cyclic nucleotide-binding domain...    41   0.019
UniRef50_Q1EWQ8 Cluster: Cyclic nucleotide-binding:regulatory pr...    41   0.019
UniRef50_A5PA10 Cluster: Cyclic nucleotide-binding protein; n=1;...    41   0.019
UniRef50_UPI0000D56B62 Cluster: PREDICTED: similar to Potassium/...    40   0.025
UniRef50_Q72VQ9 Cluster: Cyclic nucleotide binding protein; n=4;...    40   0.025
UniRef50_Q0LK35 Cluster: Cyclic nucleotide-binding; n=1; Herpeto...    40   0.025
UniRef50_Q0FXM0 Cluster: Putative catabolite gene activator; n=1...    40   0.025
UniRef50_A7IGJ4 Cluster: Cyclic nucleotide-binding protein; n=1;...    40   0.025
UniRef50_A7HF79 Cluster: Cyclic nucleotide-binding protein; n=1;...    40   0.025
UniRef50_A0LNW4 Cluster: Transcriptional regulator, Crp/Fnr fami...    40   0.025
UniRef50_Q22YR2 Cluster: Cyclic nucleotide-binding domain contai...    40   0.025
UniRef50_A7STN1 Cluster: Predicted protein; n=2; Nematostella ve...    40   0.025
UniRef50_A7RGK0 Cluster: Predicted protein; n=1; Nematostella ve...    40   0.025
UniRef50_A0BIM1 Cluster: Chromosome undetermined scaffold_11, wh...    40   0.025
UniRef50_Q6BWV4 Cluster: Debaryomyces hansenii chromosome B of s...    40   0.025
UniRef50_UPI0000D556B8 Cluster: PREDICTED: similar to cyclic nuc...    40   0.034
UniRef50_UPI00006CFB0C Cluster: cyclic nucleotide-binding domain...    40   0.034
UniRef50_UPI00006CE534 Cluster: cyclic nucleotide-binding domain...    40   0.034
UniRef50_UPI00006CCBC9 Cluster: cyclic nucleotide-binding domain...    40   0.034
UniRef50_UPI000065F344 Cluster: Cyclic nucleotide-gated olfactor...    40   0.034
UniRef50_Q4T9V2 Cluster: Chromosome undetermined SCAF7488, whole...    40   0.034
UniRef50_Q4SKL1 Cluster: Chromosome undetermined SCAF14565, whol...    40   0.034
UniRef50_Q98GN8 Cluster: Mll3241 protein; n=2; Rhizobiales|Rep: ...    40   0.034
UniRef50_O83286 Cluster: Catabolite gene activator; n=2; Trepone...    40   0.034
UniRef50_Q2N5Y8 Cluster: Cyclic nucleotide-binding; n=1; Erythro...    40   0.034
UniRef50_Q12IK7 Cluster: Cyclic nucleotide-binding; n=1; Shewane...    40   0.034
UniRef50_A6G6X5 Cluster: Predicted signal transduction protein c...    40   0.034
UniRef50_A0L8L8 Cluster: Cyclic nucleotide-binding protein; n=1;...    40   0.034
UniRef50_Q89CE1 Cluster: Blr7856 protein; n=2; Bradyrhizobium|Re...    40   0.045
UniRef50_Q74BP9 Cluster: Transcriptional regulator, Crp/Fnr fami...    40   0.045
UniRef50_Q21JY8 Cluster: Cyclic nucleotide-binding; n=1; Sacchar...    40   0.045
UniRef50_Q12FL8 Cluster: Cyclic nucleotide-binding; n=1; Polarom...    40   0.045
UniRef50_A4BEG8 Cluster: Putative uncharacterized protein; n=1; ...    40   0.045
UniRef50_A4B0Y5 Cluster: Cyclic nucleotide-binding protein; n=1;...    40   0.045
UniRef50_A3VL67 Cluster: Putative uncharacterized protein; n=1; ...    40   0.045
UniRef50_Q23K39 Cluster: Cation channel family protein; n=1; Tet...    40   0.045
UniRef50_Q23AA5 Cluster: Cyclic nucleotide-binding domain contai...    40   0.045
UniRef50_A4VDK5 Cluster: Voltage and ligand gated potassium chan...    40   0.045
UniRef50_Q24278 Cluster: Cyclic nucleotide-gated cation channel;...    40   0.045
UniRef50_Q82GX1 Cluster: Putative transcriptional regulator with...    39   0.059
UniRef50_Q7NK18 Cluster: Gll1662 protein; n=1; Gloeobacter viola...    39   0.059
UniRef50_Q0ANV8 Cluster: Cyclic nucleotide-binding protein; n=2;...    39   0.059
UniRef50_Q076H6 Cluster: N-acyl phenylalanine synthase; n=1; unc...    39   0.059
UniRef50_A5CYD6 Cluster: Hypothetical transcriptional regulator;...    39   0.059
UniRef50_A1ZRY9 Cluster: Transporter, small conductance mechanos...    39   0.059
UniRef50_Q01CK0 Cluster: Predicted esterase of the alpha-beta hy...    39   0.059
UniRef50_Q23K40 Cluster: Cyclic nucleotide-binding domain contai...    39   0.059
UniRef50_Q23EB8 Cluster: Cyclic nucleotide-binding domain contai...    39   0.059
UniRef50_Q22AP6 Cluster: Cation channel family protein; n=1; Tet...    39   0.059
UniRef50_O97119 Cluster: Cyclic nucleotide-gated ion channel LCN...    39   0.059
UniRef50_A2DY06 Cluster: Cyclic nucleotide-binding domain contai...    39   0.059
UniRef50_Q5KQ28 Cluster: Vacuole protein, putative; n=1; Filobas...    39   0.059
UniRef50_UPI0000384141 Cluster: COG0664: cAMP-binding proteins -...    39   0.078
UniRef50_Q6MLB6 Cluster: Putative uncharacterized protein; n=1; ...    39   0.078
UniRef50_Q6MIF1 Cluster: Probable cyclic nucleotide binding prot...    39   0.078
UniRef50_Q30QZ1 Cluster: Putative transcriptional regulator, Crp...    39   0.078
UniRef50_Q0AWK5 Cluster: Putative uncharacterized protein; n=1; ...    39   0.078
UniRef50_Q03UH4 Cluster: Crp-like transcriptional regulator; n=2...    39   0.078
UniRef50_A7C611 Cluster: Cyclic nucleotide-binding; n=1; Beggiat...    39   0.078
UniRef50_A0UXQ0 Cluster: Transcriptional regulator, Crp/Fnr fami...    39   0.078
UniRef50_Q23CM8 Cluster: Cyclic nucleotide-binding domain contai...    39   0.078
UniRef50_A0DV88 Cluster: Chromosome undetermined scaffold_65, wh...    39   0.078
UniRef50_Q2HCN1 Cluster: Putative uncharacterized protein; n=1; ...    39   0.078
UniRef50_Q0TZR7 Cluster: Putative uncharacterized protein; n=1; ...    39   0.078
UniRef50_A5DFW8 Cluster: Putative uncharacterized protein; n=1; ...    39   0.078
UniRef50_P92960 Cluster: Potassium channel KAT3; n=7; core eudic...    39   0.078
UniRef50_UPI0000D568C5 Cluster: PREDICTED: similar to sperm-spec...    38   0.10 
UniRef50_Q7NIH1 Cluster: Glr2212 protein; n=2; Cyanobacteria|Rep...    38   0.10 
UniRef50_Q7M956 Cluster: PUTATIVE TRANSCRIPTIONAL REGULATOR; n=1...    38   0.10 
UniRef50_Q44026 Cluster: Orf2 protein; n=3; Cupriavidus|Rep: Orf...    38   0.10 
UniRef50_Q04QT5 Cluster: CAMP-binding protein; n=4; Leptospira|R...    38   0.10 
UniRef50_A5NX32 Cluster: Cyclic nucleotide-binding protein; n=1;...    38   0.10 
UniRef50_A4TW57 Cluster: cAMP-binding proteins-catabolite gene a...    38   0.10 
UniRef50_A1IDX0 Cluster: Putative transcriptional regulator, Crp...    38   0.10 
UniRef50_A1EWE7 Cluster: Conserved domain protein; n=5; Coxiella...    38   0.10 
UniRef50_A0DKI0 Cluster: Chromosome undetermined scaffold_54, wh...    38   0.10 
UniRef50_A7EKJ1 Cluster: Putative uncharacterized protein; n=1; ...    38   0.10 
UniRef50_Q5ZVB5 Cluster: CAAX amino terminal protease family pro...    38   0.14 
UniRef50_Q2W0D8 Cluster: CAMP-binding protein-catabolite gene ac...    38   0.14 
UniRef50_Q51661 Cluster: Fnr-like transcriptional activator; n=2...    38   0.14 
UniRef50_Q0PQI4 Cluster: Transcriptional regulator Crp/Fnr; n=1;...    38   0.14 
UniRef50_A6NUW6 Cluster: Putative uncharacterized protein; n=1; ...    38   0.14 
UniRef50_Q22YR4 Cluster: Cyclic nucleotide-binding domain contai...    38   0.14 
UniRef50_Q22U43 Cluster: Cyclic nucleotide-binding domain contai...    38   0.14 
UniRef50_A0E0P5 Cluster: Chromosome undetermined scaffold_72, wh...    38   0.14 
UniRef50_Q6CWE3 Cluster: Similarities with ca|CA0961|IPF18822 Ca...    38   0.14 
UniRef50_UPI0000F1EB53 Cluster: PREDICTED: hypothetical protein,...    38   0.18 
UniRef50_UPI0000DB7A09 Cluster: PREDICTED: similar to CG8958-PA;...    38   0.18 
UniRef50_UPI00006CB9F6 Cluster: cation channel family protein; n...    38   0.18 
UniRef50_UPI00006CB8EE Cluster: cyclic nucleotide-binding domain...    38   0.18 
UniRef50_Q21HQ8 Cluster: Cyclic nucleotide-binding; n=1; Sacchar...    38   0.18 
UniRef50_Q1K454 Cluster: Cyclic nucleotide-binding protein; n=1;...    38   0.18 
UniRef50_A7HRV0 Cluster: Putative transcriptional regulator, Crp...    38   0.18 
UniRef50_A0NZG3 Cluster: CAMP-binding protein-catabolite gene ac...    38   0.18 
UniRef50_A0LQJ4 Cluster: Cyclic nucleotide-binding protein; n=1;...    38   0.18 
UniRef50_Q9W201 Cluster: CG3536-PA; n=3; Sophophora|Rep: CG3536-...    38   0.18 
UniRef50_Q23AA6 Cluster: Cation channel family protein; n=1; Tet...    38   0.18 
UniRef50_Q22U44 Cluster: Cyclic nucleotide-binding domain contai...    38   0.18 
UniRef50_A0D169 Cluster: Chromosome undetermined scaffold_34, wh...    38   0.18 
UniRef50_UPI0000F21589 Cluster: PREDICTED: similar to 240K prote...    37   0.24 
UniRef50_UPI00006CAF68 Cluster: cyclic nucleotide-binding domain...    37   0.24 
UniRef50_UPI0000383B0E Cluster: COG0664: cAMP-binding proteins -...    37   0.24 
UniRef50_Q8G502 Cluster: Probable transcriptional regulator with...    37   0.24 
UniRef50_Q7WBP4 Cluster: Probable regulator; n=2; Bordetella|Rep...    37   0.24 
UniRef50_Q6MNF7 Cluster: Putative uncharacterized protein; n=1; ...    37   0.24 
UniRef50_Q6AL49 Cluster: Probable transcription regulator; n=1; ...    37   0.24 
UniRef50_Q5L1Y8 Cluster: Transcriptional regulator; n=3; Bacilla...    37   0.24 
UniRef50_Q2SHS2 Cluster: CAMP-binding protein-catabolite gene ac...    37   0.24 
UniRef50_Q21SN7 Cluster: Transcriptional regulator, Crp/Fnr fami...    37   0.24 
UniRef50_Q1K2E6 Cluster: Cyclic nucleotide-binding protein; n=1;...    37   0.24 
UniRef50_Q0S8M5 Cluster: Transcriptional regulator; n=50; Actino...    37   0.24 
UniRef50_Q07HN5 Cluster: Transcriptional regulator, Crp/Fnr fami...    37   0.24 
UniRef50_A7DIK0 Cluster: Cyclic nucleotide-binding protein; n=2;...    37   0.24 
UniRef50_A7C5Z1 Cluster: Putative uncharacterized protein; n=1; ...    37   0.24 
UniRef50_A6UE01 Cluster: Cyclic nucleotide-binding protein; n=5;...    37   0.24 
UniRef50_A5NVT2 Cluster: Cyclic nucleotide-binding protein; n=1;...    37   0.24 
UniRef50_A1ARS9 Cluster: Transcriptional regulator, Crp/Fnr fami...    37   0.24 
UniRef50_Q22TM9 Cluster: Cyclic nucleotide-binding domain contai...    37   0.24 
UniRef50_P0ACK1 Cluster: Catabolite gene activator; n=101; Gamma...    37   0.24 
UniRef50_Q9SJA4 Cluster: Probable cyclic nucleotide-gated ion ch...    37   0.24 
UniRef50_UPI00006CC92E Cluster: cyclic nucleotide-binding domain...    37   0.31 
UniRef50_Q5LKQ8 Cluster: Cyclic nucleotide-binding protein; n=3;...    37   0.31 
UniRef50_Q4ZZV6 Cluster: Cyclic nucleotide-binding; n=3; Pseudom...    37   0.31 
UniRef50_Q8VQZ4 Cluster: Histidine kinase-like protein; n=2; Myx...    37   0.31 
UniRef50_Q4C464 Cluster: Cyclic nucleotide-binding:Sulfate trans...    37   0.31 
UniRef50_A0NV10 Cluster: Cyclic nucleotide-binding:Bacterial reg...    37   0.31 
UniRef50_Q248A3 Cluster: Cyclic nucleotide-binding domain contai...    37   0.31 
UniRef50_Q22C85 Cluster: Cation channel family protein; n=1; Tet...    37   0.31 
UniRef50_A0DK81 Cluster: Chromosome undetermined scaffold_54, wh...    37   0.31 
UniRef50_A7TIE8 Cluster: Putative uncharacterized protein; n=1; ...    37   0.31 
UniRef50_UPI00006CF2CA Cluster: cyclic nucleotide-binding domain...    36   0.41 
UniRef50_Q4SDJ0 Cluster: Chromosome 18 SCAF14637, whole genome s...    36   0.41 
UniRef50_Q5ZY24 Cluster: Putative uncharacterized protein; n=4; ...    36   0.41 
UniRef50_Q31RQ1 Cluster: Cyclic nucleotide-binding domain (CNMP-...    36   0.41 
UniRef50_Q31M75 Cluster: Cyclic nucleotide-binding domain (CNMP-...    36   0.41 
UniRef50_Q2AH01 Cluster: Cyclic nucleotide-binding:Bacterial reg...    36   0.41 
UniRef50_Q121L3 Cluster: Cyclic nucleotide-binding domain (CNMP-...    36   0.41 
UniRef50_A7HBD8 Cluster: Putative uncharacterized protein; n=1; ...    36   0.41 
UniRef50_A6G9I3 Cluster: Cyclic nucleotide-binding domain (CNMP-...    36   0.41 

>UniRef50_Q7PPI8 Cluster: ENSANGP00000022232; n=3;
           Endopterygota|Rep: ENSANGP00000022232 - Anopheles
           gambiae str. PEST
          Length = 381

 Score =  239 bits (585), Expect = 3e-62
 Identities = 112/165 (67%), Positives = 139/165 (84%)
 Frame = +2

Query: 20  KPPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQ 199
           KP V R+ +RRKSVFAETYDPE DD DEGA A+FPK+D QRARL ++V+ ILLFRSLD +
Sbjct: 75  KPLVNRYASRRKSVFAETYDPENDDEDEGARAIFPKTDEQRARLCDSVKNILLFRSLDKE 134

Query: 200 QMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS 379
           QM +VLDAMFEK  +  +Y+I+QGDDGDNFYVIE+G+++  V G+D  +K +HTY+  GS
Sbjct: 135 QMNEVLDAMFEKIVQAKDYIIKQGDDGDNFYVIESGIYNAYV-GED--QKHIHTYDNRGS 191

Query: 380 FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
           FGELAL+YNMPRAA+++A+T G LWAMDR TFRRILLKSAF+KRK
Sbjct: 192 FGELALLYNMPRAATIQAETDGKLWAMDRQTFRRILLKSAFRKRK 236



 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 37/122 (30%), Positives = 62/122 (50%), Gaps = 1/122 (0%)
 Frame = +2

Query: 125 KSDAQRARLAEAVR-GILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIE 301
           KS  ++ ++ EA+   + + ++L   +   + DA+  +    G+ +I+QGD  D  Y IE
Sbjct: 229 KSAFRKRKMYEALLDAVPMLKTLQNYERMNLADALIPQTYAKGDRIIKQGDAADGMYFIE 288

Query: 302 NGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481
           +G   + +   D  E  +   E  G FGELAL+ + PRAAS  A     +  +D   F R
Sbjct: 289 DGKVSIRIQ-QDAGEVEISNLEKGGYFGELALVTHRPRAASAYAVDNVKVAFLDVDAFER 347

Query: 482 IL 487
           +L
Sbjct: 348 LL 349


>UniRef50_P81900 Cluster: cAMP-dependent protein kinase type II
           regulatory subunit; n=17; Eumetazoa|Rep: cAMP-dependent
           protein kinase type II regulatory subunit - Drosophila
           melanogaster (Fruit fly)
          Length = 377

 Score =  232 bits (568), Expect = 3e-60
 Identities = 109/165 (66%), Positives = 138/165 (83%)
 Frame = +2

Query: 20  KPPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQ 199
           +PPV   ++RRKSVFAE YDPE DD D+GA AVFPK+D QRARL E+V+ +LLFRSL+ +
Sbjct: 73  EPPVMA-SSRRKSVFAEAYDPEADDDDDGATAVFPKTDEQRARLVESVKNVLLFRSLEKE 131

Query: 200 QMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS 379
           QM QVLDAMFE++ +PG+++IRQGDDGDNFYVIE+GV+ V +      +K ++TY  +G 
Sbjct: 132 QMNQVLDAMFERKVQPGDFIIRQGDDGDNFYVIESGVYKVYIN-----DKHINTYNHTGL 186

Query: 380 FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
           FGELAL+YNMPRAA+V+A+T+G LWAMDR TFRRILLKSAF+KRK
Sbjct: 187 FGELALLYNMPRAATVQAETSGLLWAMDRQTFRRILLKSAFRKRK 231



 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 41/119 (34%), Positives = 61/119 (51%), Gaps = 2/119 (1%)
 Frame = +2

Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316
           +R    E +  + + ++L   +   + DA+  K  + GE +I+QGD  D  Y IE G   
Sbjct: 229 KRKMYEELLNSVPMLKALQNYERMNLADALVSKSYDNGERIIKQGDAADGMYFIEEGTVS 288

Query: 317 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGA--LWAMDRHTFRRIL 487
           V +  DD   ++    +G   FGELAL+ + PRAASV A T G   L  +D   F R+L
Sbjct: 289 VRMDQDDAEVEISQLGKGQ-YFGELALVTHRPRAASVYA-TGGVVKLAFLDVKAFERLL 345


>UniRef50_Q5DI18 Cluster: SJCHGC02266 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC02266 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 377

 Score =  192 bits (467), Expect = 5e-48
 Identities = 93/158 (58%), Positives = 115/158 (72%), Gaps = 1/158 (0%)
 Frame = +2

Query: 44  NRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDA 223
           +RR  V AE+YDPE+DDS      V PK++ QR RL +A + ILLFR LD  QM+ V+DA
Sbjct: 74  SRRAGVAAESYDPEKDDSSSAVKVVHPKTEEQRQRLTQATKDILLFRCLDDDQMKDVIDA 133

Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV-TGDDRVEKVVHTYEGSGSFGELALM 400
           MFE+   PGE VI  G+DGDNFYVIE GV+D++V  GD+  EKVV  Y+  GSFGELALM
Sbjct: 134 MFERHVSPGEKVITLGEDGDNFYVIEKGVYDIIVKVGDE--EKVVGKYDNKGSFGELALM 191

Query: 401 YNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
           YN PRAA++ A+T G LWAM R  FR I+LK AF+KR+
Sbjct: 192 YNTPRAATILAKTEGVLWAMTREVFRSIVLKKAFEKRR 229



 Score = 71.3 bits (167), Expect = 1e-11
 Identities = 42/125 (33%), Positives = 62/125 (49%), Gaps = 1/125 (0%)
 Frame = +2

Query: 116 VFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYV 295
           V  K+  +R    E +  + +  SL A +   + DA+  K  E  E +I+QGD GD  + 
Sbjct: 220 VLKKAFEKRRLYEELLNQVPILESLSAYERMSIADALRTKIFEANEQIIKQGDPGDEMFF 279

Query: 296 IENGVFDV-LVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHT 472
           +E G   + +    +  EK V   E  G FGELAL+ + PRAAS  A     L  +D  +
Sbjct: 280 VEEGKVSIKMKRSGETEEKEVAVIEKGGYFGELALLTSHPRAASAYADCRTKLAVLDVGS 339

Query: 473 FRRIL 487
           F R+L
Sbjct: 340 FERLL 344


>UniRef50_P31323 Cluster: cAMP-dependent protein kinase type II-beta
           regulatory subunit; n=56; Deuterostomia|Rep:
           cAMP-dependent protein kinase type II-beta regulatory
           subunit - Homo sapiens (Human)
          Length = 418

 Score =  189 bits (460), Expect = 4e-47
 Identities = 94/164 (57%), Positives = 119/164 (72%)
 Frame = +2

Query: 23  PPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQ 202
           P + RF  RR SV AE Y+P+E++ D  +  + PK+D QR RL EA + ILLF++LD +Q
Sbjct: 104 PVINRFT-RRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQ 162

Query: 203 MQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF 382
           M QVLDAMFEK  + GE+VI QGDDGDNFYVI+ G FD+ V  D  V + V  Y+  GSF
Sbjct: 163 MSQVLDAMFEKLVKDGEHVIDQGDDGDNFYVIDRGTFDIYVKCDG-VGRCVGNYDNRGSF 221

Query: 383 GELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
           GELALMYN PRAA++ A + GALW +DR TFRRI++K+  KKRK
Sbjct: 222 GELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRK 265



 Score = 63.7 bits (148), Expect = 2e-09
 Identities = 42/131 (32%), Positives = 69/131 (52%), Gaps = 7/131 (5%)
 Frame = +2

Query: 116 VFPKSDAQRARLAEA-VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFY 292
           +  K++A++ ++ E+ +  +   +SL+  +  +V+D +  K    GE +I QGD  D+F+
Sbjct: 255 IIVKNNAKKRKMYESFIESLPFLKSLEFSERLKVVDVIGTKVYNDGEQIIAQGDSADSFF 314

Query: 293 VIENGVFDVLV--TGDDRVEK--VVHTYEGSGS--FGELALMYNMPRAASVRAQTAGALW 454
           ++E+G   + +   G   VE+   V     S    FGELAL+ N PRAAS  A       
Sbjct: 315 IVESGEVKITMKRKGKSEVEENGAVEMPRCSRGQYFGELALVTNKPRAASAHAIGTVKCL 374

Query: 455 AMDRHTFRRIL 487
           AMD   F R+L
Sbjct: 375 AMDVQAFERLL 385


>UniRef50_Q4RSC3 Cluster: Chromosome 13 SCAF15000, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 13
           SCAF15000, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 422

 Score =  173 bits (422), Expect = 2e-42
 Identities = 92/175 (52%), Positives = 118/175 (67%), Gaps = 11/175 (6%)
 Frame = +2

Query: 23  PPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQ 202
           P + RF+ RR SV AE ++P+ED+ ++      PK+D QR RL EA R ILLF++LD ++
Sbjct: 127 PVINRFS-RRASVCAEAFNPDEDEEEKEPLVTHPKTDEQRQRLQEACRDILLFKNLDPEE 185

Query: 203 MQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF 382
           M QVLDAMFEK    GE++I Q DDGDNFYVIE+G F + V   D  EK+V  Y+  GSF
Sbjct: 186 MSQVLDAMFEKFCTEGEHIIDQDDDGDNFYVIESGTFSIFVK-TDSTEKLVGCYDNRGSF 244

Query: 383 GELALMYNMPRAASVRAQTAGALWAM-----------DRHTFRRILLKSAFKKRK 514
           GELALMYN PRAA++ A + GALW +           DR TFRRI++K+  KKRK
Sbjct: 245 GELALMYNTPRAATIIATSTGALWCLAIKATQQEKQQDRLTFRRIIVKNNAKKRK 299



 Score = 33.9 bits (74), Expect = 2.2
 Identities = 22/53 (41%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
 Frame = +2

Query: 332 DDRVEKV-VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
           D   E+V + T      FGELAL+ N PRAAS  A  +     MD   F R+L
Sbjct: 344 DPEEEEVDIATLSRGQYFGELALVTNKPRAASAYAVGSVKCLVMDVKAFERLL 396


>UniRef50_P31320 Cluster: cAMP-dependent protein kinase regulatory
           subunit; n=1; Blastocladiella emersonii|Rep:
           cAMP-dependent protein kinase regulatory subunit -
           Blastocladiella emersonii (Aquatic fungus)
          Length = 403

 Score =  148 bits (359), Expect = 6e-35
 Identities = 81/164 (49%), Positives = 97/164 (59%)
 Frame = +2

Query: 23  PPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQ 202
           PPV     RR SV AE+  P   D D     V PKSD QRAR+  ++    LFR+LD  Q
Sbjct: 107 PPVVN-RGRRTSVSAESMAPTAHDVD-AVKTVIPKSDEQRARIQASIGNNFLFRNLDEDQ 164

Query: 203 MQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF 382
              V++AM EK+   GE VIRQG  GD FYV+E G  DV V  +   +  V  Y   GSF
Sbjct: 165 YTDVVNAMAEKKVAAGEVVIRQGGVGDYFYVVETGALDVFVNRNGNGDVKVTDYSAGGSF 224

Query: 383 GELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
           GELALMYN PRAA+V A     LWA+DR TFRRIL+    +KR+
Sbjct: 225 GELALMYNAPRAATVVATAESVLWALDRVTFRRILMDHTSRKRR 268



 Score = 66.5 bits (155), Expect = 3e-10
 Identities = 38/119 (31%), Positives = 64/119 (53%), Gaps = 1/119 (0%)
 Frame = +2

Query: 134 AQRARLAEA-VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGV 310
           +++ R+ EA +  + L  SL+  +  ++ DA+       G+ VIRQGD G+NFY+IE G 
Sbjct: 264 SRKRRMYEAFLEEVPLLSSLEPYERHKIADALESVAYADGDVVIRQGDVGENFYIIEAGD 323

Query: 311 FDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
            +V+   ++  E           FGELAL+ + PR A++RA+       + +  F R+L
Sbjct: 324 AEVIKIDENGEEHHFRPLHKGNYFGELALLSDKPRVATIRAKGKLKCAKLGKKAFTRLL 382


>UniRef50_A7RGJ3 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 390

 Score =  139 bits (336), Expect = 4e-32
 Identities = 71/156 (45%), Positives = 98/156 (62%)
 Frame = +2

Query: 47  RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226
           RR SV  E Y+P   +    A   +PKS+  R RL   +  I +F+S    Q+  +LDAM
Sbjct: 88  RRDSVAGEVYEPVNSNC-VSAQRFYPKSEDARKRLENVIGNIFIFKSCGKDQINMMLDAM 146

Query: 227 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYN 406
           +E+     E +IRQGD GDNFY+I+ G F+VL   +   EK +   +G GSFGELALMYN
Sbjct: 147 YERVVYQEETIIRQGDAGDNFYIIDEGEFEVLFETNGAQEK-LGRLKGPGSFGELALMYN 205

Query: 407 MPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
            PR+A++RA T G LW +DR +FRRIL+ +  +KR+
Sbjct: 206 CPRSATIRACTPGVLWVLDRKSFRRILVDTTERKRR 241



 Score = 49.2 bits (112), Expect = 6e-05
 Identities = 36/123 (29%), Positives = 58/123 (47%), Gaps = 3/123 (2%)
 Frame = +2

Query: 128 SDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG 307
           ++ +R      +  I +   L A +   + DA+        E +IRQ D  D  Y IE+G
Sbjct: 236 TERKRRHYETLLERIPVLSQLTAYERTSLADALTTSVYRDEECIIRQDDPADCLYFIESG 295

Query: 308 VFDVLV-TGDDRVE-KVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWA-MDRHTFR 478
           + ++ +    DR + KV+ T      FGELAL+    R ASV A+      A ++ + F 
Sbjct: 296 IVEISIRDSKDRSKVKVISTAGPGEYFGELALVNKTKRGASVHAKGGQVTCAVLEVNAFE 355

Query: 479 RIL 487
           R+L
Sbjct: 356 RLL 358


>UniRef50_A7S513 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 373

 Score =  132 bits (319), Expect = 5e-30
 Identities = 67/164 (40%), Positives = 103/164 (62%), Gaps = 1/164 (0%)
 Frame = +2

Query: 26  PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQM 205
           P+ +  +RR +V AE Y+P E+ +D  A    PKS+ QR  L + +  + LF     + +
Sbjct: 75  PIIKGRSRRAAVSAEPYNPNEN-ADFKAK-FHPKSEEQRNHLKKKLLELWLFEKFHREDL 132

Query: 206 QQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKV-VHTYEGSGSF 382
             +LD+MFEK+  P E +I+ GD+GDNFYVI  G +DV     +    + VHT+ G+G F
Sbjct: 133 DVILDSMFEKKVSPEEIIIKVGDEGDNFYVINTGEYDVFALDTNTGASIKVHTFNGTGMF 192

Query: 383 GELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
           GELALM+N  R A++ A+T G LWA+DR TF ++++  A ++R+
Sbjct: 193 GELALMHNSLRNATIVAKTEGTLWALDRSTFVQVVVGGAQRRRE 236



 Score = 62.5 bits (145), Expect = 6e-09
 Identities = 40/118 (33%), Positives = 62/118 (52%), Gaps = 1/118 (0%)
 Frame = +2

Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDN-FYVIENGVF 313
           +R R  E ++ + + + L   ++ +V DA++ K  + GE VIR+G++     Y IE G  
Sbjct: 234 RRERNIELLKSVSILKELKPDELDKVSDALYPKEFKDGEAVIREGNESAYCMYFIEKGKV 293

Query: 314 DVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
            V V  D  VEK V        FGELAL+ N PR+ASV A       ++ +  F R++
Sbjct: 294 RVTVK-DGEVEKTVEF--DKNYFGELALVMNQPRSASVYAVGECKFASLKKDDFERLM 348


>UniRef50_A6SCU8 Cluster: Putative uncharacterized protein; n=2;
           Sclerotiniaceae|Rep: Putative uncharacterized protein -
           Botryotinia fuckeliana B05.10
          Length = 468

 Score =  132 bits (318), Expect = 6e-30
 Identities = 79/165 (47%), Positives = 99/165 (60%), Gaps = 9/165 (5%)
 Frame = +2

Query: 47  RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226
           RR SV AE+ +P    +D  +P    K+  Q ARL +++ G  LF  LD +Q  QVL A+
Sbjct: 169 RRTSVSAESLNPTASSNDNWSPPFHQKTQDQVARLKKSISGNFLFSHLDDEQSAQVLGAL 228

Query: 227 FEKR-SEPGEYVIRQGDDGDNFYVIENGVFDV-------LVTGDDRVEKVVHTYEGSGSF 382
            EK     G  VI QGD GD FYV+E G FDV       L  G D +   V T E  GSF
Sbjct: 229 VEKPIPAVGIKVISQGDQGDFFYVVEKGSFDVHVNSTGSLQPGPDGLGTKVATIEPGGSF 288

Query: 383 GELALMYNMPRAASV-RAQTAGALWAMDRHTFRRILLKSAFKKRK 514
           GELALMYN PRAA+V  A+ +  LWA+DR TFRRIL+ S F++R+
Sbjct: 289 GELALMYNAPRAATVISAEASCTLWALDRITFRRILMDSTFQRRR 333



 Score = 67.7 bits (158), Expect = 1e-10
 Identities = 40/121 (33%), Positives = 68/121 (56%), Gaps = 1/121 (0%)
 Frame = +2

Query: 128 SDAQRARLAEA-VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 304
           S  QR RL E+ +  + L  +L   +  ++ DA+  ++  PG  +I +GD G+ FY++E+
Sbjct: 327 STFQRRRLYESFLEEVPLLSTLTRYERSKIADALETQKYPPGTAIINEGDAGEAFYLLES 386

Query: 305 GVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484
           G  +    G   V+  V  Y     FGELAL+ + PRAASV ++T   +  + ++ F+R+
Sbjct: 387 GEAEAYKRG---VDNPVKLYHKGDYFGELALLNDAPRAASVVSKTEVKVATLGKNGFQRL 443

Query: 485 L 487
           L
Sbjct: 444 L 444


>UniRef50_Q5H7P2 Cluster: CAMP-dependent protein kinase regulatory
           subunit; n=1; Aspergillus oryzae|Rep: CAMP-dependent
           protein kinase regulatory subunit - Aspergillus oryzae
          Length = 416

 Score =  131 bits (317), Expect = 8e-30
 Identities = 77/165 (46%), Positives = 98/165 (59%), Gaps = 9/165 (5%)
 Frame = +2

Query: 47  RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226
           RR SV AE+ +P    SD   P   PK++ Q +RL  AV G  LF  LD  Q + V+DA+
Sbjct: 119 RRTSVSAESLNPTSAGSDSWVPPHHPKTEEQVSRLKTAVSGNFLFSHLDDDQFKTVVDAL 178

Query: 227 FEKR-SEPGEYVIRQGDDGDNFYVIENGVFDVLV-------TGDDRVEKVVHTYEGSGSF 382
            EK     G  VI QGD GD FY++E+G FDV +       +G D +     T    GSF
Sbjct: 179 VEKPIPAKGIKVISQGDAGDYFYIVEDGHFDVYIHPSGSVQSGSDGMGSKAGTIGPGGSF 238

Query: 383 GELALMYNMPRAAS-VRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
           GELALMYN PRAA+ V   +   LWA+DR TFRRIL+ SAF++R+
Sbjct: 239 GELALMYNAPRAATIVSTDSKSTLWALDRITFRRILMDSAFQRRR 283



 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 42/118 (35%), Positives = 67/118 (56%), Gaps = 1/118 (0%)
 Frame = +2

Query: 137 QRARLAEA-VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVF 313
           QR R+ EA +  + L  SL   +  ++ DA+   +   G  +I++GD GD FY++E+G  
Sbjct: 280 QRRRMYEAFLEEVPLLSSLKPYERSKIADALDAIKFPAGSSIIKEGDPGDAFYLLESGEA 339

Query: 314 DVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
           +    G DR  K   +Y+    FGELAL+ + PRAAS+ A+T   +  + R  F+R+L
Sbjct: 340 EAFKEGVDRPVK---SYQRGDYFGELALLDDQPRAASIVAKTDVKVAKLGRDGFKRLL 394


>UniRef50_Q86ZN7 Cluster: cAMP-dependent protein kinase regulatory
           subunit; n=23; Pezizomycotina|Rep: cAMP-dependent
           protein kinase regulatory subunit - Trichoderma
           atroviride (Hypocrea atroviridis)
          Length = 462

 Score =  130 bits (314), Expect = 2e-29
 Identities = 79/171 (46%), Positives = 100/171 (58%), Gaps = 10/171 (5%)
 Frame = +2

Query: 32  ARFN-NRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQ 208
           A++N +RR SV AE+  P  D  D   P    K+  Q  RL  A+ G  LF  LD +Q  
Sbjct: 155 AQYNFSRRTSVSAESLKPSADGFDNWTPPYTDKTPEQVERLKYAIEGNFLFSHLDDEQSA 214

Query: 209 QVLDAMFEKRSEP-GEYVIRQGDDGDNFYVIENGVFDVLVT-------GDDRVEKVVHTY 364
           Q+L A+ EK     G  VI QGD GD FYV+E G FDV V        G D +   V T 
Sbjct: 215 QILGALVEKPIPARGIKVISQGDAGDYFYVVERGSFDVYVNDCGFIEPGPDGLGNKVGTI 274

Query: 365 EGSGSFGELALMYNMPRAAS-VRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
           +  GSFGELALMYN PRAA+ + A+ +  LWA+DR TFRRIL++S F +R+
Sbjct: 275 QAGGSFGELALMYNAPRAATIISAEGSCTLWALDRVTFRRILMESTFARRR 325



 Score = 61.7 bits (143), Expect = 1e-08
 Identities = 35/118 (29%), Positives = 65/118 (55%)
 Frame = +2

Query: 134 AQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVF 313
           A+R      +  + +  SL   +  ++ DA+  ++  PG+ +I +GD G +FY++E+G  
Sbjct: 322 ARRRMYENFLEEVPILSSLTPYERSKISDALETQKFAPGDVIIHEGDPGHSFYLLESGEA 381

Query: 314 DVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
                   + E+ V +Y+    FGELAL+ + PRAASV A +   +  + ++ F+R+L
Sbjct: 382 AAF-----KGEEQVLSYKKGDFFGELALLNDAPRAASVIATSDVKVATLGKNAFQRLL 434


>UniRef50_P10644 Cluster: cAMP-dependent protein kinase type I-alpha
           regulatory subunit; n=105; Eumetazoa|Rep: cAMP-dependent
           protein kinase type I-alpha regulatory subunit - Homo
           sapiens (Human)
          Length = 381

 Score =  126 bits (305), Expect = 2e-28
 Identities = 73/163 (44%), Positives = 95/163 (58%)
 Frame = +2

Query: 26  PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQM 205
           PV +   RR ++ AE Y   E+D+      V PK     A LA+A+   +LF  LD  + 
Sbjct: 89  PVVKGRRRRGAISAEVYT--EEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNER 146

Query: 206 QQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFG 385
             + DAMF      GE VI+QGD+GDNFYVI+ G  DV V      E      EG GSFG
Sbjct: 147 SDIFDAMFSVSFIAGETVIQQGDEGDNFYVIDQGETDVYVNN----EWATSVGEG-GSFG 201

Query: 386 ELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
           ELAL+Y  PRAA+V+A+T   LW +DR ++RRIL+ S  +KRK
Sbjct: 202 ELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRK 244



 Score = 61.7 bits (143), Expect = 1e-08
 Identities = 40/118 (33%), Positives = 60/118 (50%), Gaps = 1/118 (0%)
 Frame = +2

Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316
           +R    E +  + +  SLD  +   V DA+   + E G+ ++ QG+ GD F++I  G   
Sbjct: 242 KRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAA 301

Query: 317 VLVTGDDRVEKV-VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
           VL    +  E V V     S  FGE+AL+ N PRAA+V A+       +DR  F R+L
Sbjct: 302 VLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVL 359


>UniRef50_Q4TGP1 Cluster: Chromosome undetermined SCAF3574, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF3574,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 235

 Score =  124 bits (299), Expect = 1e-27
 Identities = 60/117 (51%), Positives = 80/117 (68%), Gaps = 1/117 (0%)
 Frame = +2

Query: 41  NNRRKSVFAETYDPEEDDSDEGAPAVF-PKSDAQRARLAEAVRGILLFRSLDAQQMQQVL 217
           +NRR SV AE Y+P+ED+ ++  P V  PK+D QR RL +A + ILLF++LD +Q  ++L
Sbjct: 89  SNRRVSVCAEAYNPDEDEDEDAEPRVVNPKTDEQRRRLKDACKHILLFKTLDQEQFSEIL 148

Query: 218 DAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGE 388
           DAMFE   +P +++I QGDDGDNFYVIE G FD+ V   D     V  Y+  GSFGE
Sbjct: 149 DAMFEVLVKPQQHIIDQGDDGDNFYVIEKGTFDIFVQ-KDGASLCVGKYDNKGSFGE 204


>UniRef50_P07278 Cluster: cAMP-dependent protein kinase regulatory
           subunit; n=6; Saccharomycetales|Rep: cAMP-dependent
           protein kinase regulatory subunit - Saccharomyces
           cerevisiae (Baker's yeast)
          Length = 416

 Score =  121 bits (292), Expect = 9e-27
 Identities = 76/166 (45%), Positives = 100/166 (60%), Gaps = 3/166 (1%)
 Frame = +2

Query: 23  PPVA-RFN-NRRKSVFAETYDPEEDDSDEGAPAVFP-KSDAQRARLAEAVRGILLFRSLD 193
           PP+   FN  RR SV  ET  P  ++ D+  P  +  KS+ Q  RL +++R   LF  LD
Sbjct: 132 PPLPMHFNAQRRTSVSGETLQP--NNFDDWTPDHYKEKSEQQLQRLEKSIRNNFLFNKLD 189

Query: 194 AQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGS 373
           +   + V++ + EK    G  +I+QGD GD FYV+E G  D  V  +    KV  +  GS
Sbjct: 190 SDSKRLVINCLEEKSVPKGATIIKQGDQGDYFYVVEKGTVDFYVNDN----KVNSSGPGS 245

Query: 374 GSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511
            SFGELALMYN PRAA+V A +   LWA+DR TFR+ILL S+FKKR
Sbjct: 246 -SFGELALMYNSPRAATVVATSDCLLWALDRLTFRKILLGSSFKKR 290



 Score = 69.7 bits (163), Expect = 4e-11
 Identities = 39/118 (33%), Positives = 66/118 (55%), Gaps = 1/118 (0%)
 Frame = +2

Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316
           +R    + ++ + + +SL      ++ DA+  K  +PGE +IR+GD G+NFY+IE G  D
Sbjct: 289 KRLMYDDLLKSMPVLKSLTTYDRAKLADALDTKIYQPGETIIREGDQGENFYLIEYGAVD 348

Query: 317 VLVTGDDRVEKVV-HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
           V   G   + K+  H Y     FGE+AL+ ++PR A+V A     +  + +  F+R+L
Sbjct: 349 VSKKGQGVINKLKDHDY-----FGEVALLNDLPRQATVTATKRTKVATLGKSGFQRLL 401


>UniRef50_Q9HEW1 Cluster: cAMP-dependent protein kinase regulatory
           subunit; n=8; Saccharomycetales|Rep: cAMP-dependent
           protein kinase regulatory subunit - Candida albicans
           (Yeast)
          Length = 459

 Score =  121 bits (292), Expect = 9e-27
 Identities = 74/164 (45%), Positives = 92/164 (56%)
 Frame = +2

Query: 20  KPPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQ 199
           K PVA   NRR SV AE  +P +   D   P V   S  +   LA  ++   LF+ LDA 
Sbjct: 168 KIPVAFNANRRTSVSAEALNPAKLKLDSWKPPVNNLSITEEETLANNLKNNFLFKQLDAN 227

Query: 200 QMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS 379
             + V+ A+ +K       +I+QGD+GD FY+IE G  D  V       KV  + EGS S
Sbjct: 228 SKKTVIAALQQKSFAKDTVIIQQGDEGDFFYIIETGTVDFYVND----AKVSSSSEGS-S 282

Query: 380 FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511
           FGELALMYN PRAA+  A T    WA+DR TFRRILL+  F KR
Sbjct: 283 FGELALMYNSPRAATAVAATDVVCWALDRLTFRRILLEGTFNKR 326



 Score = 54.4 bits (125), Expect = 1e-06
 Identities = 31/117 (26%), Positives = 64/117 (54%)
 Frame = +2

Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316
           +R    + ++ I + +SL      ++ DA+  +    G+ ++ +G+ G+NFY+IE+G   
Sbjct: 325 KRLMYEDFLKDIEVLKSLSDHARSKLADALSTEMYHKGDKIVTEGEQGENFYLIESGNCQ 384

Query: 317 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
           V    ++++  +    +G   FGELAL+ ++PR A+V A     +  + +  F+R+L
Sbjct: 385 VY---NEKLGNIKQLTKGD-YFGELALIKDLPRQATVEALDNVIVATLGKSGFQRLL 437


>UniRef50_Q9HFV9 Cluster: CAMP dependent protein kinase regulatory
           subunit; n=3; Filobasidiella neoformans|Rep: CAMP
           dependent protein kinase regulatory subunit -
           Cryptococcus neoformans var. neoformans
          Length = 482

 Score =  120 bits (289), Expect = 2e-26
 Identities = 74/160 (46%), Positives = 98/160 (61%), Gaps = 16/160 (10%)
 Frame = +2

Query: 83  EEDDS----DEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPG 250
           EED++    + G P VFPKS+ Q AR+ +A++   LFR+LD +Q   VL AM E + + G
Sbjct: 185 EEDENTVNLNSGTP-VFPKSEEQLARIRQAIKPNFLFRNLDDEQEADVLAAMKEVKVDAG 243

Query: 251 EYVIRQGDDGDNFYVIENGVFDVLVTGDDRV------------EKVVHTYEGSGSFGELA 394
           E VI QG  GD FY++ENG  DV V  + +V            +KV    EGS SFGELA
Sbjct: 244 EVVIEQGAAGDFFYIVENGRLDVFVNKEGQVLDLEKGDRQGLGKKVAECSEGS-SFGELA 302

Query: 395 LMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
           LM+N PRAAS+ + T   LWA+DR +FR ILL    +KR+
Sbjct: 303 LMHNAPRAASIISLTPCTLWALDRVSFRTILLDHTSRKRR 342



 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 41/121 (33%), Positives = 64/121 (52%), Gaps = 3/121 (2%)
 Frame = +2

Query: 134 AQRARLAEA-VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGV 310
           +++ RL E+ +  + +  SL  Q+  ++ D +  +    GE VIRQGD GD F++IE+G 
Sbjct: 338 SRKRRLYESFLSEVPILASLQPQERAKIADVLESRTYNEGEDVIRQGDAGDEFFLIESGN 397

Query: 311 FDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGAL--WAMDRHTFRRI 484
              + T +D    VV        FGELAL+    RAA++RA+    L   A+    F R+
Sbjct: 398 AMAIKTDEDGNASVVKHLGQGEYFGELALLNRRTRAATIRAEGPDKLRVAALGEQAFTRL 457

Query: 485 L 487
           L
Sbjct: 458 L 458


>UniRef50_Q240X5 Cluster: Cyclic nucleotide-binding domain
           containing protein; n=2; Eukaryota|Rep: Cyclic
           nucleotide-binding domain containing protein -
           Tetrahymena thermophila SB210
          Length = 414

 Score =  115 bits (277), Expect = 6e-25
 Identities = 59/172 (34%), Positives = 99/172 (57%), Gaps = 1/172 (0%)
 Frame = +2

Query: 2   EXYFVKKPPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLF 181
           E + +++    +    R SV AE Y    +      P V  K + Q+ R+   +    +F
Sbjct: 104 EHHIIQQQQKNKGKGMRASVSAEAYG-SFNKKGSYVPKVVHKEEEQKKRIEHRLMQAFMF 162

Query: 182 RSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT-GDDRVEKVVH 358
           ++LD ++ + V++AM E +  PG+++I+QG+DGDN YV++ G  D       D  +  + 
Sbjct: 163 QALDEKEREIVVNAMTEVKFSPGDWIIKQGEDGDNLYVVDQGELDCYKKFSKDAEDTYLK 222

Query: 359 TYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
           TY    +FGELAL+YN PRAAS++A+T   L+++DR  F  I+ +SA K+R+
Sbjct: 223 TYMPGEAFGELALLYNAPRAASIKAKTDSILFSLDRECFNNIVKESAIKRRE 274



 Score = 77.4 bits (182), Expect = 2e-13
 Identities = 42/117 (35%), Positives = 68/117 (58%)
 Frame = +2

Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316
           +R R  + ++ + L  S+D  +   + D + + + + GEYVIR+G++G  FY+IE G   
Sbjct: 272 RRERFEQTLQKVELLDSMDPYERVHLADGIRDIKHKAGEYVIREGEEGKYFYMIEEGQLK 331

Query: 317 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
              T ++  E  V+ Y+    FGELAL+ N+PR A+V A T   L  +D  TF+R+L
Sbjct: 332 ATKT-ENGHEVQVYEYKEGDYFGELALVKNIPRQANVIATTDVKLMYLDHDTFKRLL 387


>UniRef50_Q5DAR5 Cluster: SJCHGC05163 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC05163 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 172

 Score =  113 bits (272), Expect = 2e-24
 Identities = 54/95 (56%), Positives = 73/95 (76%), Gaps = 2/95 (2%)
 Frame = +2

Query: 47  RRKSVFAETYDPEED--DSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLD 220
           RR+SV AE++DPE+D  D++E    ++PKSD+QRARL  AV+ ILLFR LD +Q  +V+D
Sbjct: 53  RRQSVAAESFDPEKDSDDNNEEERQIYPKSDSQRARLTNAVKEILLFRCLDEEQKSKVID 112

Query: 221 AMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV 325
           AM E + + G+ VI QGDDGDNFYVIE+G +D+ V
Sbjct: 113 AMQEMKVKQGDVVITQGDDGDNFYVIESGTYDIYV 147


>UniRef50_Q9BMY7 Cluster: CAMP-dependent protein kinase regulatory
           subunit; n=1; Toxoplasma gondii|Rep: CAMP-dependent
           protein kinase regulatory subunit - Toxoplasma gondii
          Length = 385

 Score =  111 bits (268), Expect = 7e-24
 Identities = 63/156 (40%), Positives = 89/156 (57%), Gaps = 1/156 (0%)
 Frame = +2

Query: 50  RKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMF 229
           R+SV AE Y          AP V+PK+  Q+ R+ + +    LF SLD + ++ V++A  
Sbjct: 92  RQSVSAEAYGEWNKRKKFVAP-VYPKTAEQKERITKVIESSFLFSSLDIEDLETVINAFQ 150

Query: 230 EKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT-GDDRVEKVVHTYEGSGSFGELALMYN 406
           E   + G  +IRQGDDGD  Y+IE G  DV+     ++  K +       +FGELALMYN
Sbjct: 151 EVSVKKGTVIIRQGDDGDRLYLIETGEVDVMKKFPGEKENKFLCKMHPGDAFGELALMYN 210

Query: 407 MPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
            PRAA+V A     LWA+DR +F  I+  +A KKR+
Sbjct: 211 APRAATVIAADDMLLWALDRDSFTNIVRDAAAKKRE 246



 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 40/132 (30%), Positives = 73/132 (55%)
 Frame = +2

Query: 92  DSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQG 271
           D D     V   +  +R    E+++ + +   +D  +  ++ DA+     E G+ +I++G
Sbjct: 229 DRDSFTNIVRDAAAKKREIFEESLKEVRILEDMDPYERSKLSDALRTATYEDGDVIIKEG 288

Query: 272 DDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGAL 451
           + GD FY++  G  + +     + +KVV  Y+  G FGELAL+ + PRAA+V A++   +
Sbjct: 289 ETGDTFYILLEGAAEAI-----KNDKVVMEYKKGGFFGELALLKDQPRAATVVAKSHVQV 343

Query: 452 WAMDRHTFRRIL 487
             MDR +F+R+L
Sbjct: 344 AYMDRKSFKRLL 355


>UniRef50_Q22NC5 Cluster: Cyclic nucleotide-binding domain
           containing protein; n=5; Oligohymenophorea|Rep: Cyclic
           nucleotide-binding domain containing protein -
           Tetrahymena thermophila SB210
          Length = 381

 Score =  111 bits (268), Expect = 7e-24
 Identities = 60/155 (38%), Positives = 95/155 (61%)
 Frame = +2

Query: 50  RKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMF 229
           R SV AE Y      S   A  + PK+  Q  R+ + +    +F+SLD  + + V+ AM 
Sbjct: 94  RTSVSAEAYGQYNQKSAFVAKNI-PKNANQVLRIKQRLSQAFMFQSLDENEQRVVIGAME 152

Query: 230 EKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNM 409
           EK+ + GE +I+QGDDGD  YV+++G+ D      ++ + ++ TY+   +FGELAL+YN 
Sbjct: 153 EKKFKAGETIIKQGDDGDELYVVDSGLLDCYKEKANQEKILLKTYKEGEAFGELALLYNA 212

Query: 410 PRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
           PRAA++ A+T   L+++DR TF  I+  +A KKR+
Sbjct: 213 PRAATIIAKTDCILFSLDRPTFNHIVKDAAAKKRE 247



 Score = 68.5 bits (160), Expect = 8e-11
 Identities = 32/96 (33%), Positives = 62/96 (64%), Gaps = 3/96 (3%)
 Frame = +2

Query: 209 QVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVF---DVLVTGDDRVEKVVHTYEGSGS 379
           Q+ DA+   +   G+Y++++G++G++F+++E G+     V+  G   V+  V+ Y+    
Sbjct: 269 QIADALHSHKFSKGDYIVKEGENGNSFFILEEGIAVATKVMQAGQAPVK--VYEYKSGDY 326

Query: 380 FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
           FGE+AL+ N  RAA+V A++   + +MDR +F+R+L
Sbjct: 327 FGEIALLKNQTRAANVIAESDCTVVSMDRESFKRLL 362


>UniRef50_A0DZ01 Cluster: Chromosome undetermined scaffold_7, whole
           genome shotgun sequence; n=7; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_7,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 377

 Score =  111 bits (267), Expect = 9e-24
 Identities = 61/167 (36%), Positives = 96/167 (57%), Gaps = 1/167 (0%)
 Frame = +2

Query: 17  KKPPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDA 196
           K+P  AR   +R S+ AE Y  + +  +   P V  K+  Q+ ++ + +    +F SLD 
Sbjct: 73  KRPAAAR--KQRASISAEAYG-QYNRKESFQPRVIVKTQQQKEKIGKRLEQSFMFASLDQ 129

Query: 197 QQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT-GDDRVEKVVHTYEGS 373
           ++   V+DAM E+     ++VI+QGD+GDN YV++ G  +       D   K +  Y   
Sbjct: 130 REKDIVIDAMEERSYNAEDWVIQQGDNGDNLYVVDQGELNCYKRFTKDGENKFLKVYYPG 189

Query: 374 GSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
            SFGELAL+YN PRAAS++ +T   L+A+DR TF  I+  +A +KR+
Sbjct: 190 ESFGELALLYNAPRAASIQCKTNSILFALDRQTFNHIVKDAAMRKRE 236



 Score = 80.2 bits (189), Expect = 3e-14
 Identities = 45/120 (37%), Positives = 70/120 (58%), Gaps = 3/120 (2%)
 Frame = +2

Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG--- 307
           +R +    ++ I L   +D  +   V DA+     + G+YVIR+G+ GD FY+IE+G   
Sbjct: 234 KREKYVNVLKQIELLSMMDPYERSHVADAIRSANFQNGDYVIREGEQGDIFYMIEDGDLI 293

Query: 308 VFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
               LV G + V+  V  Y+    FGELAL+ ++PR A++ AQT   L  +DRH+F+R+L
Sbjct: 294 ATKTLVQGQEPVK--VFQYKTGDYFGELALLKDIPRQANIVAQTEVKLIYLDRHSFKRML 351


>UniRef50_Q7KQK0 Cluster: CAMP-dependent protein kinase regulatory
           subunit, putative; n=7; Plasmodium|Rep: CAMP-dependent
           protein kinase regulatory subunit, putative - Plasmodium
           falciparum (isolate 3D7)
          Length = 441

 Score =  109 bits (263), Expect = 3e-23
 Identities = 56/156 (35%), Positives = 88/156 (56%)
 Frame = +2

Query: 47  RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226
           +R SV AE Y       D   P V+ K + ++A++ EA+    LF  L+ ++ + +++A 
Sbjct: 146 KRLSVSAEAYGDWNKKIDNFIPKVYKKDEKEKAKIREALNESFLFNHLNKKEFEIIVNAF 205

Query: 227 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYN 406
           F+K  E G  +I +GD GD  YVI+ G  ++  T ++  ++V+   +    FGELAL+YN
Sbjct: 206 FDKNVEKGVNIINEGDYGDLLYVIDQGEVEIYKTKENNKKEVLTVLKSKDVFGELALLYN 265

Query: 407 MPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
             RAA+  A T   LWA+DR +F  I+     KKRK
Sbjct: 266 SKRAATATALTKCHLWALDRESFTYIIKDMVAKKRK 301



 Score = 71.7 bits (168), Expect = 9e-12
 Identities = 36/117 (30%), Positives = 69/117 (58%)
 Frame = +2

Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316
           +R    + +  + + + +D  +  +V D +  K    GE +I++G++GD F+++ +G  +
Sbjct: 299 KRKMYEDILSHVNILKDMDPYERCKVADCLKSKSYNDGEIIIKEGEEGDTFFILIDG--N 356

Query: 317 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
            + + D+   KV+ TY     FGELAL+ N PRAA+++AQ    +  +DR +F+R+L
Sbjct: 357 AVASKDN---KVIKTYTKGDYFGELALLKNKPRAATIKAQNFCQVVYLDRKSFKRLL 410


>UniRef50_Q3SED2 Cluster: CAMP-dependent protein kinase, regulatory
           subunit 3-1; n=5; Paramecium tetraurelia|Rep:
           CAMP-dependent protein kinase, regulatory subunit 3-1 -
           Paramecium tetraurelia
          Length = 369

 Score =  109 bits (262), Expect = 4e-23
 Identities = 62/157 (39%), Positives = 94/157 (59%), Gaps = 2/157 (1%)
 Frame = +2

Query: 50  RKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMF 229
           R +V AE Y  + +  ++  P    KS+ Q  R+ + +    +F++LD + +  VL AM 
Sbjct: 84  RAAVSAEVYG-DYNKKEDFKPRFIQKSEGQIERIKKRILNSFMFQALDEKDLNIVLGAMD 142

Query: 230 EKRSEPGEYVIRQGDDGDNFYVIENGVFDVL--VTGDDRVEKVVHTYEGSGSFGELALMY 403
           EK+ + G+ VI+QGDDG+  YVI+ G  +     TG +  EK++ TY    SFGELAL+Y
Sbjct: 143 EKKFQVGDEVIKQGDDGNELYVIDEGRLECYKKFTGFEE-EKLLKTYIPGESFGELALLY 201

Query: 404 NMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
           N PRAA+++A      +A+DR TF  I+  SA KKR+
Sbjct: 202 NAPRAATIKAIEEVTTFALDRETFNNIVKFSAIKKRE 238



 Score = 70.1 bits (164), Expect = 3e-11
 Identities = 40/117 (34%), Positives = 67/117 (57%)
 Frame = +2

Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316
           +R ++ E +  I L +S+D  +  Q+ D + E++   GE +I +G+ GD  Y+I  G  +
Sbjct: 236 KREQMEEILNKIDLLQSMDNYERVQLCDVLKEEKHHAGEAIINEGEIGDRIYLIIEGELE 295

Query: 317 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
               G  + EK V+ Y+    FGELAL+ N PR A+V A+T   L   D ++F+R++
Sbjct: 296 AYWKG--QTEK-VYDYKSGDYFGELALLKNTPRQATVIAKTDVVLLYCDFNSFKRLM 349


>UniRef50_UPI0001509E09 Cluster: cyclic nucleotide-binding domain
           containing protein; n=2; Tetrahymena thermophila
           SB210|Rep: cyclic nucleotide-binding domain containing
           protein - Tetrahymena thermophila SB210
          Length = 331

 Score =  108 bits (259), Expect = 8e-23
 Identities = 58/157 (36%), Positives = 93/157 (59%), Gaps = 1/157 (0%)
 Frame = +2

Query: 47  RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226
           +R SV AE Y    +  +   P V  KS   + ++ + +    +F  LD ++ + +++AM
Sbjct: 47  QRNSVSAEAYGMF-NKRENFKPIVIAKSQDTKNKIYKRINEAFMFNCLDLKEREIIVNAM 105

Query: 227 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKV-VHTYEGSGSFGELALMY 403
            EKR + G+ VI+QG++G+  YVI+ G  D      ++ E   + TY+   SFGELAL+Y
Sbjct: 106 EEKRFKSGDQVIKQGEEGNYLYVIDEGQLDCFKKYQNQPEPTYLKTYQPGESFGELALLY 165

Query: 404 NMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
           N PRAAS+ ++T   L+A+DR TF  I+  +A KKR+
Sbjct: 166 NAPRAASIVSKTPSVLFALDRETFNHIVKDAAMKKRQ 202


>UniRef50_P49605 Cluster: cAMP-dependent protein kinase regulatory
           subunit; n=1; Ustilago maydis|Rep: cAMP-dependent
           protein kinase regulatory subunit - Ustilago maydis
           (Smut fungus)
          Length = 525

 Score =  108 bits (259), Expect = 8e-23
 Identities = 74/180 (41%), Positives = 102/180 (56%), Gaps = 17/180 (9%)
 Frame = +2

Query: 23  PPVARFN-NRRKSVFAETYDPEEDDSD-EGAP---AVFPKSDAQRARLAEAVRGILLFRS 187
           PP   FN  RR SV AE+  P   +++ +G+P    V PKS+ Q  R+  ++   LLFR+
Sbjct: 160 PPT--FNLGRRTSVSAESMAPSAANAESDGSPLPKTVIPKSEEQMQRIRGSIGNNLLFRN 217

Query: 188 LDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRV-------- 343
           L+  Q + VL AM E + +    VI QG  GD FYV+E G  DV V   D V        
Sbjct: 218 LEQDQYRDVLLAMKEVKVDANVTVIEQGAQGDYFYVVEFGTLDVYVRSPDAVSEGAPSAS 277

Query: 344 ----EKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511
               +K V +Y    SFGELAL+Y  PRAA+V + +A  LWA+DR TFR IL+++  ++R
Sbjct: 278 ALLGDKKV-SYGPGSSFGELALLYAQPRAATVLSTSACTLWALDRITFRSILMETNSRRR 336



 Score = 56.4 bits (130), Expect = 4e-07
 Identities = 36/102 (35%), Positives = 53/102 (51%)
 Frame = +2

Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316
           +RA   + +  + LF  L A +  ++ D++  +    GE VI QG+ G  F++I  G  +
Sbjct: 335 RRALYEKFLMDVPLFERLSAAERAKISDSLELREYSRGEAVISQGERGSEFFIIVEGDAE 394

Query: 317 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTA 442
           V  T     E+VV        FGELAL+ N PRAA+V A  A
Sbjct: 395 VRKTKQGG-EEVVGKLSRGDYFGELALLNNAPRAATVAAAGA 435


>UniRef50_P05987 Cluster: cAMP-dependent protein kinase regulatory
           subunit; n=2; Dictyostelium discoideum|Rep:
           cAMP-dependent protein kinase regulatory subunit -
           Dictyostelium discoideum (Slime mold)
          Length = 327

 Score =  107 bits (256), Expect = 2e-22
 Identities = 63/159 (39%), Positives = 93/159 (58%), Gaps = 1/159 (0%)
 Frame = +2

Query: 41  NNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLD 220
           N  RK   A + +P  D      P + PK+   + RL +A+   ++F  L+ ++   V  
Sbjct: 22  NITRKRRGAISSEPLGDKPATPLPNI-PKTVETQQRLEQALSNNIMFSHLEEEERNVVFL 80

Query: 221 AMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV-TGDDRVEKVVHTYEGSGSFGELAL 397
           AM E   + G+ +I+QGD+GD FYVI++G+ D+ V         V+  +EG GSFGELAL
Sbjct: 81  AMVEVLYKAGDIIIKQGDEGDLFYVIDSGICDIYVCQNGGSPTLVMEVFEG-GSFGELAL 139

Query: 398 MYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
           +Y  PRAA+V A+T   LWA++  T+RRIL+    KKRK
Sbjct: 140 IYGSPRAATVIARTDVRLWALNGATYRRILMDQTIKKRK 178



 Score = 66.5 bits (155), Expect = 3e-10
 Identities = 39/119 (32%), Positives = 58/119 (48%), Gaps = 3/119 (2%)
 Frame = +2

Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG--- 307
           +R    E +  + + R +D  +   + DA+     + GE ++RQGD GD FY+I  G   
Sbjct: 176 KRKLYEEFLEKVSILRHIDKYERVSLADALEPVNFQDGEVIVRQGDPGDRFYIIVEGKVV 235

Query: 308 VFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484
           V    V GD     VV     S  FGE+AL+ + PRAA+V +        +DR  F R+
Sbjct: 236 VTQETVPGDHSTSHVVSELHPSDYFGEIALLTDRPRAATVTSIGYTKCVELDRQRFNRL 294


>UniRef50_Q6C2X0 Cluster: cAMP-dependent protein kinase regulatory
           subunit; n=1; Yarrowia lipolytica|Rep: cAMP-dependent
           protein kinase regulatory subunit - Yarrowia lipolytica
           (Candida lipolytica)
          Length = 375

 Score =  105 bits (252), Expect = 6e-22
 Identities = 67/162 (41%), Positives = 91/162 (56%)
 Frame = +2

Query: 26  PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQM 205
           P A F  RR SV AE+  P          A    S  Q   L ++V    LF +LD +  
Sbjct: 94  PAAPFT-RRTSVSAESIAPGAFAGAASGVASNNLSAEQLESLYKSVSHNFLFGNLDEEAC 152

Query: 206 QQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFG 385
           + VL ++ EK+ + GE +I QGD+GD FY++E+G  + +  G     KV  +  GS SFG
Sbjct: 153 RSVLQSLQEKKCDSGEKIITQGDEGDYFYIVESGAVEFIKDG----VKVNSSGPGS-SFG 207

Query: 386 ELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511
           ELALMYN PRAA+V A     LW++DR TFR+ILL    ++R
Sbjct: 208 ELALMYNAPRAATVVATQPCVLWSLDRVTFRKILLDGTHQRR 249



 Score = 62.5 bits (145), Expect = 6e-09
 Identities = 34/109 (31%), Positives = 63/109 (57%)
 Frame = +2

Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
           ++ + +   L + +  ++ DA+  +  EPG  VI +G+ GD FY++E+G  +V   G+  
Sbjct: 256 LKEVPILSDLGSYERNKLADALTSQVVEPGTAVITEGEAGDAFYLVESGEAEVTKKGE-- 313

Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
              VV T +    FGE+AL+ ++PR A+V A+T   +  + +  F+R+L
Sbjct: 314 -SGVVATLKQGDYFGEVALLNDLPRQATVTAKTKLKVATLGKDGFQRLL 361


>UniRef50_Q9XTM6 Cluster: CAMP-dependent protein kinase regulatory
           subunit; n=1; Euplotes octocarinatus|Rep: CAMP-dependent
           protein kinase regulatory subunit - Euplotes
           octocarinatus
          Length = 338

 Score =  104 bits (250), Expect = 1e-21
 Identities = 54/134 (40%), Positives = 80/134 (59%), Gaps = 1/134 (0%)
 Frame = +2

Query: 116 VFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYV 295
           V PKSD  + ++   +    LF SLD + ++ V++AM  K  EP   VI+QGDDG   ++
Sbjct: 70  VVPKSDELKTQIRTRLLQSFLFSSLDDRDLEIVINAMEVKTFEPSSTVIKQGDDGAELFL 129

Query: 296 IENGVFDVL-VTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHT 472
           +  G  D   V       K++  YE   +FGELAL+YN PRAA+++A+T   L+++DR T
Sbjct: 130 VGEGTLDCFKVMKKGEEAKLIKEYEPGDAFGELALLYNAPRAATIKAKTEAVLYSLDRDT 189

Query: 473 FRRILLKSAFKKRK 514
           F  I+  SA KKR+
Sbjct: 190 FNLIVKDSAAKKRE 203



 Score = 81.8 bits (193), Expect = 8e-15
 Identities = 42/120 (35%), Positives = 72/120 (60%), Gaps = 3/120 (2%)
 Frame = +2

Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG--- 307
           +R +  + ++ + +  S+   +  Q+ DA+ E++  PG+YVI+QG+ GD FY+I  G   
Sbjct: 201 KREKYEKCLKNVKVLDSVSIYERSQIADAIKEQKFNPGDYVIKQGEIGDTFYMISEGEAT 260

Query: 308 VFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
            + +   G    E + +TY     FGE+AL+ N PRAASV A+T   +  +DR++FRR++
Sbjct: 261 AYKIFEEGGKEEEVMKYTY--GDYFGEIALLKNEPRAASVVAKTDLIVMKLDRNSFRRMI 318


>UniRef50_A0CJF2 Cluster: Chromosome undetermined scaffold_2, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_2,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 585

 Score =  104 bits (250), Expect = 1e-21
 Identities = 48/133 (36%), Positives = 82/133 (61%)
 Frame = +2

Query: 116 VFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYV 295
           V PK+  Q++R+ + +    LF+ L+ QQ + V +AM EK+ +  E +I+QGDDGD  ++
Sbjct: 317 VIPKNKDQKSRVQKKINTCYLFKHLNDQQKEIVANAMEEKKYKATETIIKQGDDGDQLFL 376

Query: 296 IENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTF 475
           ++ G+ D    G    +K++ +Y+    FGE+AL+YN  RAA++ A T   LWA+D+ TF
Sbjct: 377 VDQGLLDCQKRGKQIEDKIIKSYQPGDFFGEMALLYNEKRAATIIAFTECVLWALDKETF 436

Query: 476 RRILLKSAFKKRK 514
              + +   +KR+
Sbjct: 437 DTFIKQPVLEKRQ 449



 Score = 59.3 bits (137), Expect = 5e-08
 Identities = 32/106 (30%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTG--DDRVEK 349
           + + +D    QQ+ DA++    +  E V +Q D GD FY+I+ G    L  G  D+  E+
Sbjct: 460 ILQQIDPYLRQQIADALYVVSFKADEVVFKQKDKGDYFYLIQEGQLKALKKGDEDEDEEQ 519

Query: 350 VVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
            V  +     FGELA++  + R A++  +T   L  +D+ +F ++L
Sbjct: 520 CVFEFGEFDYFGELAMLKEINRQATIVCETDCILLGLDKQSFTKLL 565


>UniRef50_A0BRC9 Cluster: Chromosome undetermined scaffold_122,
           whole genome shotgun sequence; n=4; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_122,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 374

 Score =  104 bits (249), Expect = 1e-21
 Identities = 56/164 (34%), Positives = 90/164 (54%), Gaps = 2/164 (1%)
 Frame = +2

Query: 26  PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQM 205
           PV      R SV AE +    +  +   P V PK++ Q+ ++ E +  + +F++L   + 
Sbjct: 78  PVKNAKTFRSSVSAEVFGVH-NKKENFIPRVIPKTEEQKQQILEKLMKVFMFQALGQHEQ 136

Query: 206 QQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL--VTGDDRVEKVVHTYEGSGS 379
           + V++AM EK     ++VI QGDDG   Y++ +G  D    +   D   K +  Y+    
Sbjct: 137 EIVVNAMEEKHYTKDDWVITQGDDGAELYIVFSGELDCFRKMKPTDPEPKFLKKYKPGDM 196

Query: 380 FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511
           FGEL+L+YN PRAAS++A+    L+A+DR TF  I+  +  KKR
Sbjct: 197 FGELSLLYNSPRAASIQAKEDSVLFALDRSTFNNIVKDATIKKR 240



 Score = 72.5 bits (170), Expect = 5e-12
 Identities = 34/117 (29%), Positives = 69/117 (58%)
 Frame = +2

Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316
           +R +  E +  + L +S++A +  Q+ D + E+  + GE +I++G++GD FY++  G   
Sbjct: 239 KRLQYEEVLSKVELLQSMEAYEKTQICDGLKEQTYQKGEVIIQEGEEGDKFYMVAEGTLA 298

Query: 317 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
                + +  +V+  Y+    FGELAL++ +PR A++ A+T   +  +D ++F R+L
Sbjct: 299 AYKDNNGQQVEVLR-YQPGDYFGELALIHKLPRQATIIAETQCVVVYLDSNSFLRLL 354


>UniRef50_Q8TF77 Cluster: cAMP-dependent protein kinase regulatory
           subunit; n=4; Mucoraceae|Rep: cAMP-dependent protein
           kinase regulatory subunit - Rhizomucor racemosus (Mucor
           circinelloides f. lusitanicus)
          Length = 427

 Score =  104 bits (249), Expect = 1e-21
 Identities = 55/131 (41%), Positives = 78/131 (59%)
 Frame = +2

Query: 122 PKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIE 301
           P+      R+  ++    LFR+LD +Q   V++AM EKR   G  VI QG  GD FYV+E
Sbjct: 167 PQISGTSERIKVSISNNFLFRNLDEEQYLDVVNAMSEKRVVKGTTVIEQGSVGDFFYVVE 226

Query: 302 NGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481
           +G  D  + G ++V      YE  GSFGELALMYN PRAA++   +   LWA+DR+T   
Sbjct: 227 SGTLDCFI-GQNKVTN----YEAGGSFGELALMYNAPRAATIITTSDSVLWALDRNTSAP 281

Query: 482 ILLKSAFKKRK 514
            L+++  +KR+
Sbjct: 282 SLMENTSRKRR 292



 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 40/132 (30%), Positives = 74/132 (56%)
 Frame = +2

Query: 92  DSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQG 271
           D +  AP++   +  +R      +  ++L +SL++ +  ++ DA+     E G+ V++QG
Sbjct: 275 DRNTSAPSLMENTSRKRRMYEYFLSEVVLLKSLESYEQHKIADALESVYFEDGQEVVKQG 334

Query: 272 DDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGAL 451
           D GD FY+IE+G   +++  ++ V++ V+  E    FGELAL+ + PRAA+V A      
Sbjct: 335 DVGDQFYIIESGE-AIVLKEENGVQQQVNQLERGSYFGELALLNDAPRAATVVAHGRLKC 393

Query: 452 WAMDRHTFRRIL 487
             + +  F R+L
Sbjct: 394 ATLGKKAFTRLL 405


>UniRef50_A0BNE3 Cluster: Chromosome undetermined scaffold_118,
           whole genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_118,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 374

 Score =  103 bits (247), Expect = 2e-21
 Identities = 59/157 (37%), Positives = 90/157 (57%), Gaps = 2/157 (1%)
 Frame = +2

Query: 50  RKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMF 229
           R SV AE Y      ++   P +  KS  Q  ++ E +    +F  LD   ++ V++AM 
Sbjct: 87  RASVSAEVYGIYNKKTNF-KPKIVAKSHLQIQKIKEKLAQSFMFSELDEHDLRIVINAME 145

Query: 230 EKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT--GDDRVEKVVHTYEGSGSFGELALMY 403
             + + G+ +IRQGDDGDN Y+++ G  D   T  G D V   + TY+   SFGELAL+Y
Sbjct: 146 VIQCKKGDIIIRQGDDGDNLYIVDEGTLDCSRTKAGQDSVH--LKTYKPGESFGELALLY 203

Query: 404 NMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
           N PRAA++ A+    L+++DR TF  I+  +A +KR+
Sbjct: 204 NSPRAATIVAEENCVLFSLDRGTFNHIVKDAAIRKRE 240



 Score = 77.4 bits (182), Expect = 2e-13
 Identities = 40/118 (33%), Positives = 65/118 (55%), Gaps = 1/118 (0%)
 Frame = +2

Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG-VF 313
           +R R    +  + L + LD     Q+ DA+  +    G+Y++++GD+GD FY +E G   
Sbjct: 238 KRERYEYFLAHVELLQELDPYSRSQIADALKSRNFNIGDYIVKEGDEGDIFYFLEKGEAV 297

Query: 314 DVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
              V    +  + V+ Y+    FGE+AL+   PRAASV A+T   +  +DR TF+R+L
Sbjct: 298 ATKVLNQSQPAQEVYFYKEGDYFGEIALLRQAPRAASVIAETPCTVVYLDRETFKRLL 355


>UniRef50_A2R984 Cluster: Catalytic activity: ATP + a protein <=>
           ADP + a phosphoprotein; n=1; Aspergillus niger|Rep:
           Catalytic activity: ATP + a protein <=> ADP + a
           phosphoprotein - Aspergillus niger
          Length = 417

 Score =  103 bits (247), Expect = 2e-21
 Identities = 65/165 (39%), Positives = 92/165 (55%), Gaps = 9/165 (5%)
 Frame = +2

Query: 47  RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226
           RR SV AE++ P +      +   F  ++ Q  RL  AV+ + LF +LD +Q  Q+L A 
Sbjct: 79  RRNSVSAESFVPGQQSLPSTS---FDMTEEQAHRLVRAVKEVFLFSALDKEQYAQLLSAF 135

Query: 227 FEKRSE-PGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKV---VHTYEGSGS----F 382
             K     G  VI QGD GDNFY++E G FD+ +T     +     + T  GS      F
Sbjct: 136 VGKAVPIKGTNVITQGDIGDNFYIVEKGSFDIYITLASTPQPTTPSIGTKHGSAHPGDFF 195

Query: 383 GELALMYNMPRAASVRAQTAGA-LWAMDRHTFRRILLKSAFKKRK 514
           GELAL+YN PRAA++ +      LWA+D  +FRRI+ +SAF +R+
Sbjct: 196 GELALLYNAPRAATIISTEPDCHLWAIDGVSFRRIMAESAFARRR 240



 Score = 58.0 bits (134), Expect = 1e-07
 Identities = 39/109 (35%), Positives = 56/109 (51%), Gaps = 5/109 (4%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKV- 352
           L   L  +Q  ++ +A+  +R   G+ +I QGD G +F++        LV+G+ R  KV 
Sbjct: 251 LLAGLSGRQRSRIAEALQTRRYCAGDTIILQGDLGSDFFL--------LVSGEARAYKVG 302

Query: 353 ----VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
               V TY   G FGE A   N PRAAS+ A T   +  +DR  F R+L
Sbjct: 303 FVGSVKTYTSGGWFGERAFRKNAPRAASIMAITDVVVAVLDRDAFARLL 351


>UniRef50_Q4UEK0 Cluster: CAMP-dependent protein kinase regulatory
           subunit, putative; n=2; Theileria|Rep: CAMP-dependent
           protein kinase regulatory subunit, putative - Theileria
           annulata
          Length = 313

 Score =  101 bits (243), Expect = 7e-21
 Identities = 54/155 (34%), Positives = 85/155 (54%)
 Frame = +2

Query: 50  RKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMF 229
           R SV AE +      S    P  + K+  ++A++ E ++   LF  +++  +  ++ A  
Sbjct: 21  RLSVSAEVFGDNHSKSKVVIPN-YEKTPQEQAKIMEMIKRCFLFSGVNSSGLDLLVKAFD 79

Query: 230 EKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNM 409
            K + PG+ +I+QGDDGD  Y+IE+G  +V        E+ +        FGELALMYN 
Sbjct: 80  FKTANPGDVLIKQGDDGDKLYLIESGTVEVTRKNATGQEEFLCNLTAGDYFGELALMYNS 139

Query: 410 PRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
           PRAA+V A+T   LW +DR TF  ++  +  KKR+
Sbjct: 140 PRAATVVAKTEMHLWTLDRTTFNHVVRMAVIKKRE 174



 Score = 46.4 bits (105), Expect = 4e-04
 Identities = 28/104 (26%), Positives = 53/104 (50%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
           LF+ ++     ++ DA+ E+  E  E VI+QG+ G + +++  G  +  V       K+V
Sbjct: 185 LFKKVNPYDRCRLADALVERTFED-ETVIKQGEPGSSLFMVLEGQAESFVEN-----KLV 238

Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
            +Y     FGE+  +   PRA++V+A+       ++R  F  +L
Sbjct: 239 KSYNPGDYFGEIGFILKKPRASTVKAKGKCLFVELERENFINLL 282


>UniRef50_A3FPL6 Cluster: CAMP-dependent protein kinase regulatory
           subunit; n=2; Cryptosporidium|Rep: CAMP-dependent
           protein kinase regulatory subunit - Cryptosporidium
           parvum Iowa II
          Length = 345

 Score =  100 bits (239), Expect = 2e-20
 Identities = 58/153 (37%), Positives = 81/153 (52%)
 Frame = +2

Query: 50  RKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMF 229
           R SV AE Y       D   P+ +PK+  Q  R+ E +    +F SLD  +++ V+ A  
Sbjct: 58  RTSVSAEAYGAWNKMKDFTPPS-YPKTKEQEKRIREKLLESFMFTSLDDDELKTVILACV 116

Query: 230 EKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNM 409
           E   +    +I QGD+GD  Y+I+ GV +          K +       +FGELAL+YN 
Sbjct: 117 ETSVKKDTEIITQGDNGDKLYIIDQGVVECYKKTSTEPRKHLCDLNPGDAFGELALLYNC 176

Query: 410 PRAASVRAQTAGALWAMDRHTFRRILLKSAFKK 508
           PRAASV A+T   LWA+DR TF  I+  SA K+
Sbjct: 177 PRAASVVAKTDCLLWALDRETFNHIVKGSASKR 209



 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 36/109 (33%), Positives = 63/109 (57%)
 Frame = +2

Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
           ++ + + +++D  ++ ++   +     E G+ +I+QG+ GD FY+I  G    L    D 
Sbjct: 217 LKEVEILKTMDVYELNKLTMVLKSSIFEDGQEIIKQGEQGDTFYLIITGNAVAL---KDN 273

Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
           VE  V +Y+    FGELAL+ N PRAA+V+A+    +  +DR  F+R+L
Sbjct: 274 VE--VMSYKRGDYFGELALLRNAPRAATVKARGRCKVAYLDRKAFKRVL 320


>UniRef50_P36600 Cluster: cAMP-dependent protein kinase regulatory
           subunit; n=1; Schizosaccharomyces pombe|Rep:
           cAMP-dependent protein kinase regulatory subunit -
           Schizosaccharomyces pombe (Fission yeast)
          Length = 412

 Score = 99.1 bits (236), Expect = 5e-20
 Identities = 66/168 (39%), Positives = 96/168 (57%), Gaps = 13/168 (7%)
 Frame = +2

Query: 47  RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRA-RLAEAVRGILLFRSLDAQQMQQVLDA 223
           RR+SV  E+ +P     +      FP  D +   RL  +V G  LF++LD +   +VL+A
Sbjct: 101 RRQSVSTESMNPSAFALE--TKRTFPPKDPEDLKRLKRSVAGNFLFKNLDEEHYNEVLNA 158

Query: 224 MFEKR-SEPGEYVIRQGDDGDNFYVIENGVFDVL------VTGDDRVE----KVVHTYEG 370
           M EKR  E G  VI QG  GD FY++E G FDV       +T ++ +       + T   
Sbjct: 159 MTEKRIGEAGVAVIVQGAVGDYFYIVEQGEFDVYKRPELNITPEEVLSSGYGNYITTISP 218

Query: 371 SGSFGELALMYNMPRAASVRAQTA-GALWAMDRHTFRRILLKSAFKKR 511
              FGELALMYN PRAASV ++T    ++A+DR +FRRI+ ++A+++R
Sbjct: 219 GEYFGELALMYNAPRAASVVSKTPNNVIYALDRTSFRRIVFENAYRQR 266



 Score = 73.3 bits (172), Expect = 3e-12
 Identities = 46/124 (37%), Positives = 67/124 (54%)
 Frame = +2

Query: 116 VFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYV 295
           VF  +  QR      +  + +  SLD  Q Q++ DA+     + G  VIRQGD G+ FY+
Sbjct: 258 VFENAYRQRMLYESLLEEVPILSSLDKYQRQKIADALQTVVYQAGSIVIRQGDIGNQFYL 317

Query: 296 IENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTF 475
           IE+G  +V+  G    + VV T      FGELAL++   R A+V+A+T   L   D+ TF
Sbjct: 318 IEDGEAEVVKNG----KGVVVTLTKGDYFGELALIHETVRNATVQAKTRLKLATFDKPTF 373

Query: 476 RRIL 487
            R+L
Sbjct: 374 NRLL 377


>UniRef50_A7AU83 Cluster: cAMP-dependent protein kinase regulatory
           subunit , putative; n=1; Babesia bovis|Rep:
           cAMP-dependent protein kinase regulatory subunit ,
           putative - Babesia bovis
          Length = 317

 Score = 98.7 bits (235), Expect = 7e-20
 Identities = 64/163 (39%), Positives = 86/163 (52%), Gaps = 2/163 (1%)
 Frame = +2

Query: 32  ARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQ 211
           AR  NR  S+ AE +    +     AP V  K+  Q  R+ E V    LF S+DA+ +  
Sbjct: 17  ARARNR-VSISAEVFGAYNNPDLFVAP-VHEKTPEQATRIKETVLKCFLFSSVDAKDIDT 74

Query: 212 VLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGV--FDVLVTGDDRVEKVVHTYEGSGSFG 385
           ++ A        G  VI+QGD GD  Y+IE+G   F       ++V  +    EG G FG
Sbjct: 75  LVKAFESSDVSAGTKVIQQGDPGDKLYLIESGTARFTKTSAATEQVHDLGTAGEG-GCFG 133

Query: 386 ELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
           ELALMYN PRA SV A+T   LW++DR TF  I+  +  KKR+
Sbjct: 134 ELALMYNAPRACSVVAETDMKLWSLDRSTFNHIVRNAVIKKRE 176



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 31/112 (27%), Positives = 59/112 (52%)
 Frame = +2

Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316
           +R +    ++ + L  +LD     ++ DA+ EK +   E +I +GD G + ++I  G  +
Sbjct: 174 KREKYDSLLQSVALLSNLDPYDRCRLADALTEK-TFVDEDIIVEGDKGTSVFMILEGNAE 232

Query: 317 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHT 472
               G     K+V +Y   G FGE+AL+   PRA++V+A+    +  ++R +
Sbjct: 233 AYCQG-----KLVKSYSEGGYFGEIALIAQTPRASTVKAKGKCVVAELERES 279


>UniRef50_Q33DX2 Cluster: Putative cyclic AMP-dependent protein
           kinase regulatory subunit; n=1; Schizophyllum
           commune|Rep: Putative cyclic AMP-dependent protein
           kinase regulatory subunit - Schizophyllum commune
           (Bracket fungus)
          Length = 500

 Score = 69.3 bits (162), Expect(2) = 2e-19
 Identities = 37/102 (36%), Positives = 54/102 (52%)
 Frame = +2

Query: 20  KPPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQ 199
           +PP A    RR SV AE+   +  + +E    VFPK+  Q  R+  +     +FR L  +
Sbjct: 163 QPPNASIFARRASVSAESISVDALNREETKTRVFPKTPDQMRRIQSSTANNFIFRDLTEE 222

Query: 200 QMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV 325
           Q + V  AM E   +    VIRQGDDGD FY++E+G+    +
Sbjct: 223 QKRAVFLAMQEMTVDKDTVVIRQGDDGDYFYIVESGLLHCFI 264



 Score = 60.9 bits (141), Expect = 2e-08
 Identities = 35/102 (34%), Positives = 56/102 (54%), Gaps = 3/102 (2%)
 Frame = +2

Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316
           +R+   + +  + L  SLDA +  ++ DA+  +  E G+ V++QG+ GD F+ +E G   
Sbjct: 357 RRSMYEQFLSTVTLLSSLDASERSKIADALVSRVYEDGQAVVKQGETGDTFFFVEEGEAC 416

Query: 317 VL---VTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 433
           V      G+D  E VV   +    FGEL+L+   PRAA+V A
Sbjct: 417 VTKRPQDGEDGEEIVVGHLKKGDYFGELSLLRLAPRAATVSA 458



 Score = 48.8 bits (111), Expect(2) = 2e-19
 Identities = 24/55 (43%), Positives = 33/55 (60%)
 Frame = +2

Query: 347 KVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511
           K V  Y    SFGELALMY   RAA+V +    +LW ++R  FR +++  A K+R
Sbjct: 304 KRVAEYPAGTSFGELALMYGHARAATVLSVEPSSLWKIERRDFRHVVVGLAHKRR 358


>UniRef50_A0CMC2 Cluster: Chromosome undetermined scaffold_21, whole
           genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_21,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 334

 Score = 95.1 bits (226), Expect = 8e-19
 Identities = 57/158 (36%), Positives = 93/158 (58%), Gaps = 2/158 (1%)
 Frame = +2

Query: 47  RRKSVFAETYDPEEDDSDEGAPAVF-PKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDA 223
           +R SV AE Y   + +  E   A F PKS  Q  R+ + ++   +F +L+ ++++ V+ A
Sbjct: 50  QRFSVSAEAYG--QFNKKENFKAKFIPKSKEQSERIKQRMQAGFMFSALNEKEIEIVVGA 107

Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403
           M EK     EYVI+QG++G+  YV++ G  D       + + ++ TY    SFGELAL++
Sbjct: 108 MEEKIFHKAEYVIKQGEEGNVLYVVDTGELDCF-KNYGKGDVLLKTYYPGESFGELALLF 166

Query: 404 NMPRAASVRAQTAGA-LWAMDRHTFRRILLKSAFKKRK 514
             PRAAS+  ++  A LW +DR TF  I+ +++ KKR+
Sbjct: 167 QSPRAASIIVKSDKAILWQLDRETFNLIVKEASIKKRQ 204



 Score = 32.7 bits (71), Expect = 5.1
 Identities = 13/45 (28%), Positives = 25/45 (55%)
 Frame = +2

Query: 173 LLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG 307
           LL    D     ++ DA+FEK+ + G+ +++QG      +++E G
Sbjct: 215 LLKEIKDPYDKLKMSDALFEKQYKKGDVILQQGQKSQEIFILEQG 259


>UniRef50_UPI000065ED67 Cluster: cAMP-dependent protein kinase type
           I-beta regulatory subunit.; n=1; Takifugu rubripes|Rep:
           cAMP-dependent protein kinase type I-beta regulatory
           subunit. - Takifugu rubripes
          Length = 403

 Score = 88.2 bits (209), Expect = 1e-16
 Identities = 46/82 (56%), Positives = 58/82 (70%)
 Frame = +2

Query: 269 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGA 448
           GD+GDNFYVI+ G  DV V G    E V +  EG GSFGELAL+Y  PRAA+V+A+T   
Sbjct: 190 GDEGDNFYVIDQGEVDVYVNG----ELVTNIGEG-GSFGELALIYGTPRAATVKAKTDLK 244

Query: 449 LWAMDRHTFRRILLKSAFKKRK 514
           LW +DR ++RRIL+ S  +KRK
Sbjct: 245 LWGIDRDSYRRILMGSTLRKRK 266



 Score = 64.9 bits (151), Expect = 1e-09
 Identities = 41/118 (34%), Positives = 61/118 (51%), Gaps = 1/118 (0%)
 Frame = +2

Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316
           +R    E +  + +  SLD  +   V DA+   + E GE ++ QG  G++F++I  G+  
Sbjct: 264 KRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGEKIVVQGAPGNDFFIITEGIAS 323

Query: 317 VLVTGDDRVEKV-VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
           VL    D  E V V     S  FGE+AL+ N PRAA+V A+       +DR  F R+L
Sbjct: 324 VLQRRSDNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRIRFERVL 381


>UniRef50_UPI0000D562F1 Cluster: PREDICTED: similar to CG3324-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG3324-PA - Tribolium castaneum
          Length = 636

 Score = 86.6 bits (205), Expect = 3e-16
 Identities = 39/109 (35%), Positives = 68/109 (62%)
 Frame = +2

Query: 188 LDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYE 367
           L  +++Q V+D M+ +   P + +I++GDDG + YV   G ++V+  G     KVV T+ 
Sbjct: 70  LQNKKLQDVVDCMYPESVSPSQTIIKEGDDGSHLYVSVTGTYEVIQNG-----KVVKTFS 124

Query: 368 GSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
               FGELAL+YN  R A+++A+T G +W +DR  F+ +++ S  ++R+
Sbjct: 125 DVRVFGELALLYNAKRIATIKARTFGKVWILDRVVFKHLMVNSDIEQRQ 173



 Score = 40.3 bits (90), Expect = 0.025
 Identities = 27/104 (25%), Positives = 52/104 (50%), Gaps = 1/104 (0%)
 Frame = +2

Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGD-DGDNFYVIENGVF 313
           QR  + + ++ +    S+  + +++V   +       G  ++ +G+ + D FY+I+ G  
Sbjct: 171 QRQEIVDFLKQVPKLNSVPLEVLEEVASLLKLDFFPTGTKIVEEGEVNPDKFYIIKAGSV 230

Query: 314 DVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAG 445
            V    +  ++K+   Y+GS  FGELAL+    R A+V A   G
Sbjct: 231 TVSKKNEGAIDKL---YKGS-FFGELALLKEKERKATVMADPPG 270


>UniRef50_Q8MQE4 Cluster: Putative uncharacterized protein; n=5;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 617

 Score = 84.6 bits (200), Expect = 1e-15
 Identities = 50/131 (38%), Positives = 75/131 (57%)
 Frame = +2

Query: 116 VFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYV 295
           +  KSDA    +  A+R     R+LDA Q++++  AM+      G  +IRQGD G   YV
Sbjct: 52  IIGKSDAAFETIGNALRLNSFLRNLDATQIEKISSAMYPVEVPAGAIIIRQGDLGSIMYV 111

Query: 296 IENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTF 475
           I+ G   V V  D+R    V T E    FGELA++++  R A+VRA  +  LWA++R+ F
Sbjct: 112 IQEG--KVQVVKDNRF---VRTMEDGALFGELAILHHCERTATVRAIESCHLWAIERNVF 166

Query: 476 RRILLKSAFKK 508
             I+++SA +K
Sbjct: 167 HAIMMESAREK 177


>UniRef50_Q3SEP0 Cluster: CGMP-dependent protein kinase 8-2; n=8;
           Paramecium tetraurelia|Rep: CGMP-dependent protein
           kinase 8-2 - Paramecium tetraurelia
          Length = 795

 Score = 83.8 bits (198), Expect = 2e-15
 Identities = 45/124 (36%), Positives = 72/124 (58%)
 Frame = +2

Query: 110 PAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNF 289
           P + P++      + +  +   +F S++  Q+ Q+  +MF  R   G+ +I+QGD   +F
Sbjct: 76  PLMKPQTPQDIGFIVKCFQSHFVFSSMNETQLVQLAKSMFYCRLVIGQTIIKQGDGASSF 135

Query: 290 YVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRH 469
           +V+E G  +VLV G  R +      +G+G FGELAL+YN PR+A+  A     LW +DRH
Sbjct: 136 FVLEKGKINVLVDGISRKQLT----QGNG-FGELALLYNAPRSATCVAMEECFLWGIDRH 190

Query: 470 TFRR 481
           TFR+
Sbjct: 191 TFRK 194



 Score = 35.5 bits (78), Expect = 0.72
 Identities = 21/101 (20%), Positives = 45/101 (44%), Gaps = 1/101 (0%)
 Frame = +2

Query: 134 AQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVF 313
           +++ +  + +  +  F  L   Q   +   +  ++    E ++ +GD   +FY+I  G  
Sbjct: 202 SEQEKNRQLLEQVKFFNQLTKDQKDAIAGVLILQKFNQNEIIVNEGDQASSFYIIVEGKC 261

Query: 314 DVLVTGDDRVEKVVHTYEGSGSFGELALMY-NMPRAASVRA 433
            V     ++ +  + T     SFGE AL + N  R  +++A
Sbjct: 262 GVF----NKEDVQIATLNPKDSFGESALKHDNQIRMMTIKA 298


>UniRef50_A0E3G7 Cluster: Chromosome undetermined scaffold_76, whole
           genome shotgun sequence; n=5; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_76,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 864

 Score = 81.4 bits (192), Expect = 1e-14
 Identities = 37/104 (35%), Positives = 66/104 (63%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
           +F+S+    ++ V+D MF      G++V +QGD   ++++IE G   +++ G+     + 
Sbjct: 117 IFKSVPQSDIEYVVDQMFYCTVPDGQFVFKQGDMASSYFLIERGQCQIIINGE-----LK 171

Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
            T +   +FGELA++YN PR+ASV+A    A WA+DR+TFR+++
Sbjct: 172 KTLKSGDAFGELAMLYNAPRSASVKAIGDCAFWAIDRNTFRKVV 215



 Score = 45.6 bits (103), Expect = 7e-04
 Identities = 26/93 (27%), Positives = 47/93 (50%)
 Frame = +2

Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
           E ++ +  F  L  +Q   +   +     + GE ++ +GD  ++FY+I+ G    ++ GD
Sbjct: 228 EFMKKVEFFSFLTEEQRDAISSVLITSVFKKGEIIVSEGDVANSFYIIKKGKV-AIIKGD 286

Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 433
             V ++        SFGE AL  +  RAA+V+A
Sbjct: 287 KEVSQM----NAGESFGEAALYQSCQRAATVKA 315


>UniRef50_Q13237 Cluster: cGMP-dependent protein kinase 2; n=23;
           Euteleostomi|Rep: cGMP-dependent protein kinase 2 - Homo
           sapiens (Human)
          Length = 762

 Score = 81.0 bits (191), Expect = 1e-14
 Identities = 42/143 (29%), Positives = 79/143 (55%)
 Frame = +2

Query: 71  TYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPG 250
           TYD  +        A   K  +++  + +A+      + LD QQ++ +++ M+ +  + G
Sbjct: 133 TYDLNKPPEFSFEKARVRKDSSEKKLITDALNKNQFLKRLDPQQIKDMVECMYGRNYQQG 192

Query: 251 EYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVR 430
            Y+I+QG+ G++ +V+  G  +V      + EK++ +     +FGELA++YN  R ASV+
Sbjct: 193 SYIIKQGEPGNHIFVLAEGRLEVF-----QGEKLLSSIPMWTTFGELAILYNCTRTASVK 247

Query: 431 AQTAGALWAMDRHTFRRILLKSA 499
           A T    WA+DR  F+ I+ ++A
Sbjct: 248 AITNVKTWALDREVFQNIMRRTA 270



 Score = 53.6 bits (123), Expect = 3e-06
 Identities = 29/110 (26%), Positives = 62/110 (56%), Gaps = 3/110 (2%)
 Frame = +2

Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL--VTGD 334
           +R + L ++L   ++ +++D +  +  + G+Y+IR+G++G  F+++  G   V     G 
Sbjct: 281 LRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGH 340

Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAG-ALWAMDRHTFRR 481
           D+  +++ T +    FGE AL+ +  R+A++ A+    A   +DR TF +
Sbjct: 341 DQ-PQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETFNQ 389


>UniRef50_Q03042 Cluster: cGMP-dependent protein kinase, isozyme 1;
           n=28; Eumetazoa|Rep: cGMP-dependent protein kinase,
           isozyme 1 - Drosophila melanogaster (Fruit fly)
          Length = 768

 Score = 80.6 bits (190), Expect = 2e-14
 Identities = 40/131 (30%), Positives = 76/131 (58%), Gaps = 1/131 (0%)
 Frame = +2

Query: 119 FPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVI 298
           + K  + + ++ +A+      +++DA Q+++++D+M+ K    GE+VIR+G+ G + YV 
Sbjct: 166 YEKDFSDKQQIKDAIMDNDFLKNIDASQVRELVDSMYSKSIAAGEFVIREGEVGAHLYVS 225

Query: 299 ENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA-QTAGALWAMDRHTF 475
             G F V+  G     KV+       +FGELA++YN  R AS+R    A  +W +DR  F
Sbjct: 226 AAGEFAVMQQG-----KVLDKMGAGKAFGELAILYNCTRTASIRVLSEAARVWVLDRRVF 280

Query: 476 RRILLKSAFKK 508
           ++I++ +  ++
Sbjct: 281 QQIMMCTGLQR 291



 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 32/112 (28%), Positives = 56/112 (50%), Gaps = 3/112 (2%)
 Frame = +2

Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL--VTGD 334
           +R + L  +L  + + ++ D +  +    G Y+IRQG  GD+F++I  G   V   +T  
Sbjct: 299 LRSVPLLMNLSEELLAKIADVLELEFYAAGTYIIRQGTAGDSFFLISQGNVRVTQKLTPT 358

Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGA-LWAMDRHTFRRIL 487
              E  + T      FGE AL+    R A++ A + G     +DR +F+R++
Sbjct: 359 SPEETELRTLSRGDYFGEQALINEDKRTANIIALSPGVECLTLDRDSFKRLI 410


>UniRef50_Q16JU3 Cluster: Cgmp-dependent protein kinase; n=2;
           Endopterygota|Rep: Cgmp-dependent protein kinase - Aedes
           aegypti (Yellowfever mosquito)
          Length = 966

 Score = 77.8 bits (183), Expect = 1e-13
 Identities = 36/109 (33%), Positives = 65/109 (59%)
 Frame = +2

Query: 188 LDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYE 367
           +D ++++ V DAM      P  Y+I++GD G +F+V  +G ++V+        KV+ ++ 
Sbjct: 404 MDEERLKAVTDAMSPMTFPPNSYIIKEGDIGAHFFVSADGTYEVVAEN-----KVIKSFG 458

Query: 368 GSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
               FGELA++Y   R AS+R  T   +W ++R  F++I++KS  K+R+
Sbjct: 459 RGVVFGELAILYKAKRFASIRVTTEAKVWMLERKVFQKIMMKSGRKERE 507



 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 32/107 (29%), Positives = 55/107 (51%), Gaps = 1/107 (0%)
 Frame = +2

Query: 170 ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEK 349
           + + + L  +++ ++ D +  +    G  +I+QGD GD FY+I  G  +V+ T    V+K
Sbjct: 516 VSILKDLQTEKLHKISDLLKREFYATGSTIIQQGDPGDKFYIIRGGSVNVIKTDRHGVDK 575

Query: 350 VVHTYEGSGSFGELALMYNMPRAASVRAQTAGA-LWAMDRHTFRRIL 487
           +V T +    FGE AL++   R AS+ A   G     ++R  F   L
Sbjct: 576 LVGTLQRGAYFGEQALLHEDRRLASIIANPPGTECLTLNRIAFNEFL 622


>UniRef50_UPI0000DB6E55 Cluster: PREDICTED: similar to
           cGMP-dependent protein kinase 21D CG3324-PA; n=2;
           Apocrita|Rep: PREDICTED: similar to cGMP-dependent
           protein kinase 21D CG3324-PA - Apis mellifera
          Length = 723

 Score = 77.4 bits (182), Expect = 2e-13
 Identities = 40/132 (30%), Positives = 72/132 (54%), Gaps = 1/132 (0%)
 Frame = +2

Query: 107 APA-VFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGD 283
           AP+ V+ K +  R ++ +A+       +L+  Q++ ++ AM+ K+  P   VI++GD G 
Sbjct: 123 APSPVYEKDEKSRQQIRKAILENEFLGNLEENQVEALVSAMYSKQIPPNTLVIQEGDIGS 182

Query: 284 NFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMD 463
           + YV   G FD+      +      T+    +FGE+AL+YN  R  S++ +  G +W +D
Sbjct: 183 HLYVSAEGEFDIYEGNTFQ-----RTFGPGVAFGEIALLYNTMRLRSIKVKKGGKVWVLD 237

Query: 464 RHTFRRILLKSA 499
           R  F  +++KSA
Sbjct: 238 RSVFLTVMMKSA 249



 Score = 34.7 bits (76), Expect = 1.3
 Identities = 15/47 (31%), Positives = 26/47 (55%)
 Frame = +2

Query: 257 VIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELAL 397
           ++RQG+ G+ FY+I  G   +    +D +E+ +        FGELA+
Sbjct: 295 IVRQGEKGEKFYIISGGNVKITKDTEDGMEEELVVLGKGQYFGELAI 341


>UniRef50_Q22SE3 Cluster: Cyclic nucleotide-binding domain
           containing protein; n=1; Tetrahymena thermophila
           SB210|Rep: Cyclic nucleotide-binding domain containing
           protein - Tetrahymena thermophila SB210
          Length = 451

 Score = 76.2 bits (179), Expect = 4e-13
 Identities = 39/121 (32%), Positives = 75/121 (61%)
 Frame = +2

Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 304
           KS + +  +  +++   +F +L  ++++ V   MF   +   EYV +Q D   ++++IE+
Sbjct: 99  KSKSDQDLIMNSLKNHYVFYALTDEELEFVTQKMFYCENT-AEYVFKQEDKASSYFIIES 157

Query: 305 GVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484
           G  D+++  +D V++ ++  E   SFGELAL+YN PR+AS+R +     WA+DR++FR+ 
Sbjct: 158 GQVDIII--NDEVKRTLNPGE---SFGELALLYNAPRSASIRCKGNCHFWAIDRNSFRKT 212

Query: 485 L 487
           +
Sbjct: 213 I 213



 Score = 54.8 bits (126), Expect = 1e-06
 Identities = 31/103 (30%), Positives = 54/103 (52%)
 Frame = +2

Query: 179 FRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVH 358
           F+S++++Q   +  A+   +   GE ++ +GD  D+F++I+ G   V      + +K + 
Sbjct: 234 FKSMNSEQKDSIASALINIKFMKGENIVNEGDAADSFFMIKEGTVSVW-----KDKKEIR 288

Query: 359 TYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
                 SFGE AL  +  RAASVRA+    L ++ R    +IL
Sbjct: 289 KLGKGDSFGEQALYVSSKRAASVRAEGPVKLLSLGRDNLTKIL 331


>UniRef50_UPI0000519F68 Cluster: PREDICTED: similar to
           cGMP-dependent protein kinase 21D CG3324-PA; n=1; Apis
           mellifera|Rep: PREDICTED: similar to cGMP-dependent
           protein kinase 21D CG3324-PA - Apis mellifera
          Length = 639

 Score = 75.8 bits (178), Expect = 6e-13
 Identities = 46/153 (30%), Positives = 77/153 (50%), Gaps = 1/153 (0%)
 Frame = +2

Query: 41  NNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLD 220
           N R+ SV  E      + S +    VF K +  +  +  A+      ++ +  +++ ++ 
Sbjct: 30  NERKHSVIGEV-----NVSSDMPIKVFEKDEKTKNLIKNAILNNEFLKNFNESRIETLIS 84

Query: 221 AMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSG-SFGELAL 397
           AM+ ++ +    +I +G+ G + YV E G F + V        + +   GSG +FGELAL
Sbjct: 85  AMYPRKVKANTRIIHEGETGSHLYVSEEGTFKIYVNN------IYNENFGSGVAFGELAL 138

Query: 398 MYNMPRAASVRAQTAGALWAMDRHTFRRILLKS 496
           +YN  R  S+ A T   LW MDR  F+ I+LKS
Sbjct: 139 LYNTKRLCSIDACTDAKLWVMDRQIFQTIMLKS 171



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 23/82 (28%), Positives = 40/82 (48%)
 Frame = +2

Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
           VR I +F+    + + ++ D +  +      Y+IR+GD G+ FY+I+ G   +     + 
Sbjct: 183 VRQIEIFKDFSDEVLLKICDLIIVEFYPANSYIIREGDQGNKFYIIQGGHVKITKNKPND 242

Query: 341 VEKVVHTYEGSGSFGELALMYN 406
            E+ +   E    FGE AL  N
Sbjct: 243 KEEELMILEKGDYFGEKALYDN 264


>UniRef50_Q22RR1 Cluster: Protein kinase domain containing protein;
           n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
           domain containing protein - Tetrahymena thermophila
           SB210
          Length = 1219

 Score = 75.8 bits (178), Expect = 6e-13
 Identities = 41/119 (34%), Positives = 68/119 (57%), Gaps = 3/119 (2%)
 Frame = +2

Query: 140 RARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDV 319
           + ++  A+R   +F +L+ Q M QV++ MF    + GE++  Q D+   F+ IE G  ++
Sbjct: 437 KQKIKAAIRRHFIFSNLEEQHMNQVVNKMFACTCKQGEFIFEQNDEASLFFFIEQGNVNI 496

Query: 320 LVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGA---LWAMDRHTFRRIL 487
            +  +   +K +  +    SFGELAL+YN PR+AS +A   G    LWA+DR TF  ++
Sbjct: 497 KI--NKEFKKCLDEFT---SFGELALLYNSPRSASAQAAQDGVQLILWAIDRVTFLNVI 550



 Score = 36.7 bits (81), Expect = 0.31
 Identities = 26/111 (23%), Positives = 53/111 (47%), Gaps = 2/111 (1%)
 Frame = +2

Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
           +  +  F +   +Q   +      ++   GE ++  GDD ++FY+I++G   V +   ++
Sbjct: 565 LENVSFFSNFTHEQKDLLASQFTYQKFHKGETIVNIGDDANSFYIIKSG--QVSIISQNQ 622

Query: 341 VEKVVHTYEGSGSFGELALMYNMP-RAASVRAQTAGA-LWAMDRHTFRRIL 487
           +E+     +    FGE +L  N   R  +V+A++    L A+ R   + IL
Sbjct: 623 IEE--RQLQSGDWFGESSLYLNKSIRTRTVQAKSFDVILLALSRKATQEIL 671


>UniRef50_Q9FXQ0 Cluster: Cyclic nucreotide dependent protein kinase
           II; n=2; Chlamydomonas reinhardtii|Rep: Cyclic
           nucreotide dependent protein kinase II - Chlamydomonas
           reinhardtii
          Length = 718

 Score = 75.4 bits (177), Expect = 7e-13
 Identities = 40/115 (34%), Positives = 67/115 (58%), Gaps = 3/115 (2%)
 Frame = +2

Query: 143 ARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDG---DNFYVIENGVF 313
           A +  A+  +LLF  LD+Q  ++++  M+E+    G+ +I++GD G      YV+++G F
Sbjct: 46  AFIENALGRLLLFGKLDSQVQRKIVSEMYERTVPAGDILIKEGDTGLAACELYVVKSGKF 105

Query: 314 DVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFR 478
           +VL     +  +V +  E    FGE++LMY+ PR A+V A     +WA+DR  FR
Sbjct: 106 EVLQKRQGQNVRV-NIKERGDCFGEISLMYDSPRTATVAATMDAVVWALDRQVFR 159



 Score = 56.8 bits (131), Expect = 3e-07
 Identities = 34/119 (28%), Positives = 61/119 (51%)
 Frame = +2

Query: 131 DAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGV 310
           + Q +++   +  + +  +L  ++  +++DA  E   + G+ VI +GD GD FY+++ G 
Sbjct: 167 ETQVSQVELFLNSVPILANLSREERIRLVDAFEENTYQAGQKVIVEGDKGDLFYIVKEGE 226

Query: 311 FDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
             V         KV H ++ +  F E AL+ + PR A+V A T      + R TF+ IL
Sbjct: 227 AIVYQNTPGGQRKVNHLFK-ADFFSERALLKDEPRMATVEAYTKLVCLTLKRETFQEIL 284


>UniRef50_Q234E6 Cluster: Protein kinase domain containing protein;
           n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
           domain containing protein - Tetrahymena thermophila
           SB210
          Length = 829

 Score = 75.4 bits (177), Expect = 7e-13
 Identities = 40/109 (36%), Positives = 65/109 (59%)
 Frame = +2

Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
           +R   +F +L   Q++ +++ MF    + GE +I++ D+   F+++E G   V V   D 
Sbjct: 97  LRNHFVFYNLQDSQLETLVNEMFYCELQEGETIIKEEDNASTFFILEQGRIQVSVK--DN 154

Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
           V++ +   EG   FGELAL+YN PR+AS +A     LW +DR TFRR++
Sbjct: 155 VKRDIVPGEG---FGELALLYNAPRSASCKALQKCHLWGIDRATFRRVV 200


>UniRef50_A2EKL9 Cluster: Cyclic nucleotide-binding domain
           containing protein; n=2; Trichomonas vaginalis G3|Rep:
           Cyclic nucleotide-binding domain containing protein -
           Trichomonas vaginalis G3
          Length = 374

 Score = 75.4 bits (177), Expect = 7e-13
 Identities = 43/132 (32%), Positives = 73/132 (55%), Gaps = 1/132 (0%)
 Frame = +2

Query: 122 PKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIE 301
           PK+  +  ++    + +     L + Q+  +++A F+   +  + +I+QGD  DNFY+I+
Sbjct: 117 PKTPEEYTQIETICKKVSFLSYLKSDQLDALINAFFKMEFKDKDVIIKQGDKPDNFYIIQ 176

Query: 302 NGVFDV-LVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFR 478
           +G  D+   TGD    KV+   EGS  FGELALM    RAA+V A      WA+D+ T+ 
Sbjct: 177 SGNVDIWKKTGDAPEVKVITLSEGS-YFGELALMSGRTRAATVIAAGTVYCWAIDQTTYL 235

Query: 479 RILLKSAFKKRK 514
            +L    +++R+
Sbjct: 236 YLLKDIHYQRRQ 247



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 37/119 (31%), Positives = 59/119 (49%)
 Frame = +2

Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316
           +R +  E +  + +F  L   Q   V +A   +  +P   +I+QG+ G+ FYVI  G  D
Sbjct: 245 RRQKCKEIISEVPIFNQLPDYQAILVAEAAVLEEYQPATTIIKQGEIGNKFYVILAGTVD 304

Query: 317 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLK 493
           V++ G     K V+       FGE AL+YN  RAA++   +   +  +    FR+IL K
Sbjct: 305 VIIDG-----KKVNELGPGKYFGERALIYNCARAATIITTSQVRIAYISGEVFRKILDK 358


>UniRef50_A0D9C4 Cluster: Chromosome undetermined scaffold_42, whole
           genome shotgun sequence; n=8; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_42,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 825

 Score = 74.5 bits (175), Expect = 1e-12
 Identities = 33/120 (27%), Positives = 69/120 (57%)
 Frame = +2

Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 328
           + ++ +G  +F SL   Q+ ++++ MF    +  +++ +QGD   +++VIE G  ++++ 
Sbjct: 117 IRKSFKGHFVFFSLPEDQIAKLIEHMFYCTLKANQFIFKQGDQASSYFVIEKGSVEIIIN 176

Query: 329 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKK 508
                ++ + T      FGE+AL+YN  R+AS+R  T    W++DR TF++ + +   K+
Sbjct: 177 -----DRQIRTLAEGSYFGEIALLYNATRSASIRTLTDCGFWSLDRSTFKKTIEELMLKE 231



 Score = 52.0 bits (119), Expect = 8e-06
 Identities = 31/103 (30%), Positives = 50/103 (48%)
 Frame = +2

Query: 179 FRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVH 358
           F  + ++Q   +  A+   +  PG+ ++ +GD  D+FYVI++G   VL  G   + K+  
Sbjct: 245 FSFMTSEQKDSIAHALITTKFAPGQAIVNEGDQADSFYVIKSGEVSVL-KGTKEIRKM-- 301

Query: 359 TYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
                 SFGE AL     R A+  A+T     A+ R    +IL
Sbjct: 302 --GAKDSFGEQALYEKSKRGATCVAETEVKCVALGRENLTKIL 342


>UniRef50_A0DCJ0 Cluster: Chromosome undetermined scaffold_45, whole
           genome shotgun sequence; n=7; Oligohymenophorea|Rep:
           Chromosome undetermined scaffold_45, whole genome
           shotgun sequence - Paramecium tetraurelia
          Length = 775

 Score = 73.3 bits (172), Expect = 3e-12
 Identities = 35/102 (34%), Positives = 64/102 (62%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
           +F +L   +++ +++ MF   +  G Y+ +Q D    F++++ G  +V+V  +++ ++ +
Sbjct: 73  VFYNLSEAELENIVNKMFYCEAAAGAYIFKQQDHATCFFILQRGSLEVIV--NEKAKREL 130

Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481
            T +G   FGELAL+YN PR+ASV+      LW +DR+TFRR
Sbjct: 131 KTGDG---FGELALLYNAPRSASVKCFENCNLWGIDRNTFRR 169



 Score = 56.4 bits (130), Expect = 4e-07
 Identities = 37/121 (30%), Positives = 60/121 (49%)
 Frame = +2

Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 304
           K   +  +  E VR    F +L  +Q   +   +  ++    + ++ +GD G +FY+I+ 
Sbjct: 177 KEYEENRKFMEVVR---FFHNLTNEQKDAIAAVLIVQKFYKNQIIVNEGDPGSSFYIIKE 233

Query: 305 GVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484
           G   VL  G+  V K+   Y+G  SFGE AL YN  R  +VRA+      A+ R +  +I
Sbjct: 234 GTVSVL-KGNKEVRKL---YKGD-SFGEQALYYNTVRQMTVRAEDDVKCLALGRDSLTKI 288

Query: 485 L 487
           L
Sbjct: 289 L 289


>UniRef50_Q6P5T7 Cluster: PRKG1 protein; n=14; Euteleostomi|Rep:
           PRKG1 protein - Homo sapiens (Human)
          Length = 312

 Score = 73.3 bits (172), Expect = 3e-12
 Identities = 45/155 (29%), Positives = 78/155 (50%), Gaps = 1/155 (0%)
 Frame = +2

Query: 47  RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226
           +R+++ AE    +  D        +PKS   +  + EA+      ++L+  Q+Q+++D M
Sbjct: 75  KRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCM 134

Query: 227 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMY 403
           +         +I++GD G   YV+E+G  +V   G      V     G G  FGELA++Y
Sbjct: 135 YPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILY 188

Query: 404 NMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKK 508
           N  R A+V+      LWA+DR  F+ I++++   K
Sbjct: 189 NCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIK 223



 Score = 50.0 bits (114), Expect = 3e-05
 Identities = 28/82 (34%), Positives = 42/82 (51%), Gaps = 1/82 (1%)
 Frame = +2

Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
           E ++ +  F+SL  + + ++ D + E   E GEY+IRQG  GD F++I  G  +V     
Sbjct: 229 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 288

Query: 335 DRVEKVVHTYEGSGS-FGELAL 397
              + V     G G  FGE AL
Sbjct: 289 PSEDPVFLRTLGKGDWFGEKAL 310


>UniRef50_P14619 Cluster: cGMP-dependent protein kinase 1, beta
           isozyme; n=49; Bilateria|Rep: cGMP-dependent protein
           kinase 1, beta isozyme - Homo sapiens (Human)
          Length = 686

 Score = 73.3 bits (172), Expect = 3e-12
 Identities = 45/155 (29%), Positives = 78/155 (50%), Gaps = 1/155 (0%)
 Frame = +2

Query: 47  RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226
           +R+++ AE    +  D        +PKS   +  + EA+      ++L+  Q+Q+++D M
Sbjct: 75  KRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCM 134

Query: 227 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMY 403
           +         +I++GD G   YV+E+G  +V   G      V     G G  FGELA++Y
Sbjct: 135 YPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILY 188

Query: 404 NMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKK 508
           N  R A+V+      LWA+DR  F+ I++++   K
Sbjct: 189 NCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIK 223



 Score = 60.9 bits (141), Expect = 2e-08
 Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 1/112 (0%)
 Frame = +2

Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
           E ++ +  F+SL  + + ++ D + E   E GEY+IRQG  GD F++I  G  +V     
Sbjct: 229 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 288

Query: 335 DRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
              + V     G G  FGE AL     R A+V A  A     +DR +F+ ++
Sbjct: 289 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLI 340


>UniRef50_Q31QH3 Cluster: Cyclic nucleotide-binding; n=2;
           Synechococcus elongatus|Rep: Cyclic nucleotide-binding -
           Synechococcus sp. (strain PCC 7942) (Anacystis nidulans
           R2)
          Length = 449

 Score = 72.9 bits (171), Expect = 4e-12
 Identities = 40/113 (35%), Positives = 64/113 (56%)
 Frame = +2

Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 328
           L   +R + LFR  D  Q++ +++    +    G+ + R+G+ G+ FY+I NG F V V 
Sbjct: 291 LPSLLRRVDLFRDYDDSQIRWLIEKGRRRTCVVGDVLCREGELGEEFYLILNGRFSVQVK 350

Query: 329 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
           G    E+ + T E    FGELA+M ++PR A+V A   G L+ +DR+  R +L
Sbjct: 351 GR---EEAIATLESGNFFGELAVMLDIPRTATVVALEPGTLFVVDRNNLRHLL 400


>UniRef50_Q5RGL5 Cluster: Novel protein similar to vertebrate
           protein kinase, cGMP-dependent, type I; n=3; Danio
           rerio|Rep: Novel protein similar to vertebrate protein
           kinase, cGMP-dependent, type I - Danio rerio (Zebrafish)
           (Brachydanio rerio)
          Length = 570

 Score = 72.5 bits (170), Expect = 5e-12
 Identities = 38/126 (30%), Positives = 67/126 (53%)
 Frame = +2

Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316
           + +++ +A+      R LD +Q+  ++D M       G+ +I++G +GD+ Y++  G   
Sbjct: 1   ETSQIVKAIGKNDFLRRLDEEQISMMVDLMKVLDCRAGDEIIKEGTEGDSMYIVAAGELK 60

Query: 317 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKS 496
           V   G D     +        FGELA++YN  R ASV+A +A  LW ++R T+R I+   
Sbjct: 61  VTQAGRD-----LRILSPGDMFGELAILYNCKRTASVKAISAVKLWCIERQTYRSIMTNK 115

Query: 497 AFKKRK 514
           +  KR+
Sbjct: 116 SKMKRE 121



 Score = 54.8 bits (126), Expect = 1e-06
 Identities = 34/115 (29%), Positives = 63/115 (54%), Gaps = 1/115 (0%)
 Frame = +2

Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 304
           KS  +R +L   ++     ++L+  Q+ +++D+M E R +  E ++R+G +G+ FY+I  
Sbjct: 115 KSKMKREQLMGFLKTARTLKALNDVQLSKIIDSMEEVRFQDNEVIVREGAEGNTFYIILK 174

Query: 305 GVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDR 466
           G  +VLVT     ++      G G  FGELAL+  + R A+  A      +++D+
Sbjct: 175 G--EVLVTKKVNGQQKTIRKMGEGEHFGELALIREILRTATCTAVGVVICFSIDK 227


>UniRef50_Q8MMZ4 Cluster: CGMP-dependent protein kinase; n=14;
           Apicomplexa|Rep: CGMP-dependent protein kinase -
           Plasmodium falciparum
          Length = 853

 Score = 71.7 bits (168), Expect = 9e-12
 Identities = 45/148 (30%), Positives = 76/148 (51%)
 Frame = +2

Query: 44  NRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDA 223
           N++K++F+      ED   E    +  K       +  +++  L+  +L+  ++  + + 
Sbjct: 14  NKKKAIFSNDDFTGEDSLMEDHLELREKLSEDIDMIKTSLKNNLVCSTLNDNEILTLSNY 73

Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403
           M     + G  VI+QG+ G  F++I +G FDV V      +K V T     SFGE AL++
Sbjct: 74  MQFFVFKSGNLVIKQGEKGSYFFIINSGKFDVYVN-----DKKVKTMGKGSSFGEAALIH 128

Query: 404 NMPRAASVRAQTAGALWAMDRHTFRRIL 487
           N  R+A++ A+T G LW + R TFR  L
Sbjct: 129 NTQRSATIIAETDGTLWGVQRSTFRATL 156



 Score = 64.9 bits (151), Expect = 1e-09
 Identities = 34/110 (30%), Positives = 64/110 (58%), Gaps = 1/110 (0%)
 Frame = +2

Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
           ++ + +FR L  +Q   +++A    R E G+Y+I++G+ G  FY+I+NG  +++     +
Sbjct: 413 IKKMYIFRYLTDKQCNLLIEAFRTTRYEEGDYIIQEGEVGSRFYIIKNGEVEIV-----K 467

Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGA-LWAMDRHTFRRIL 487
            +K + T   +  FGE AL+Y+ PR ASV ++      W +D+  F +I+
Sbjct: 468 NKKRLRTLGKNDYFGERALLYDEPRTASVISKVNNVECWFVDKSVFLQII 517



 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 28/109 (25%), Positives = 54/109 (49%)
 Frame = +2

Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
           +  + +F  L   Q   + +A   +  + GE +++QGD GD  Y+++ G   V +  ++ 
Sbjct: 171 IDSVSVFDMLTEAQKNMITNACVIQNFKSGETIVKQGDYGDVLYILKEGKATVYINDEE- 229

Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
               +   E    FGE AL+Y+ PR+A++ A+   A  ++ R     +L
Sbjct: 230 ----IRVLEKGSYFGERALLYDEPRSATIIAKEPTACASICRKLLNIVL 274


>UniRef50_Q5CWD4 Cluster: Cyclic nucleotide (CGMP)-dependent protein
           kinase with 3 cNMP binding domains and a Ser/Thr kinase
           domain; n=3; Cryptosporidium|Rep: Cyclic nucleotide
           (CGMP)-dependent protein kinase with 3 cNMP binding
           domains and a Ser/Thr kinase domain - Cryptosporidium
           parvum Iowa II
          Length = 965

 Score = 71.7 bits (168), Expect = 9e-12
 Identities = 41/121 (33%), Positives = 66/121 (54%)
 Frame = +2

Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 304
           K++     +++A+ G ++  SL+  ++  ++ +M     E GE VI QG  G  F+VI  
Sbjct: 92  KTEEDIKTISKALAGNVVGASLNESEIATLVSSMHYYEYEVGEVVIEQGASGFYFFVIST 151

Query: 305 GVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484
           G F V + G+      V+T     +FGELAL++N PR+A++     G LW + R TFR  
Sbjct: 152 GSFGVEINGNR-----VNTMSEGTAFGELALIHNTPRSATILVIEKGGLWGLGRSTFRDT 206

Query: 485 L 487
           L
Sbjct: 207 L 207



 Score = 54.8 bits (126), Expect = 1e-06
 Identities = 31/115 (26%), Positives = 61/115 (53%), Gaps = 1/115 (0%)
 Frame = +2

Query: 146 RLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV 325
           R  +A++   +F+ +  QQ+  ++ ++   +   GE ++ QGD G  F+++++G   V  
Sbjct: 489 RKRDAIKSCFVFQYVSEQQLSLLVKSLRLVKFTSGEKIVVQGDKGTAFFILQSGEVAVY- 547

Query: 326 TGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGA-LWAMDRHTFRRIL 487
               R  K +     +  FGE AL+Y+  R+A++ A T    LW +D+  F +I+
Sbjct: 548 ----RNNKFIRYLGKNDYFGERALLYDELRSATIEAATPEVHLWTVDKEAFLKIV 598



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 26/109 (23%), Positives = 55/109 (50%)
 Frame = +2

Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
           +  + +F  L  +Q   + +A+  +     + +IR+ + G+  Y+I++G+  V V     
Sbjct: 222 IESLSIFSGLTDKQKSLLSEALVREIFVKDQVIIREKEIGNVLYMIKSGIVGVFVE---- 277

Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
            +K + +     +FGE +LM++ PR+A+V A        ++R    +IL
Sbjct: 278 -DKYIRSLNEGDAFGERSLMFDEPRSATVIANATTECLTLNRGILTQIL 325


>UniRef50_A7PEK0 Cluster: Chromosome chr11 scaffold_13, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr11 scaffold_13, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 1049

 Score = 70.5 bits (165), Expect = 2e-11
 Identities = 39/75 (52%), Positives = 49/75 (65%), Gaps = 5/75 (6%)
 Frame = +2

Query: 281 DNFYVIENGVFDVLVTGDDR---VEKVVHTY--EGSGSFGELALMYNMPRAASVRAQTAG 445
           D FYV+ +G F+VL T +++   V +V+  Y  E   SFGELALMYN P  ASVRA T G
Sbjct: 495 DCFYVVGSGEFEVLATQEEKNGEVTRVLQQYTAEKLSSFGELALMYNKPLQASVRAVTNG 554

Query: 446 ALWAMDRHTFRRILL 490
            LWA+ R  FR IL+
Sbjct: 555 TLWALKREDFRGILM 569


>UniRef50_Q9VL34 Cluster: CG4839-PA, isoform A; n=2; Sophophora|Rep:
           CG4839-PA, isoform A - Drosophila melanogaster (Fruit
           fly)
          Length = 1003

 Score = 69.3 bits (162), Expect = 5e-11
 Identities = 40/131 (30%), Positives = 69/131 (52%), Gaps = 1/131 (0%)
 Frame = +2

Query: 125 KSDAQRARLAEAV-RGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIE 301
           K +  R  +  A+ R   L   +D ++ + V++AM          +IR+ ++G   YV  
Sbjct: 414 KDEGTRNLIRTAIERNDFLNNLMDKERKEMVINAMAPASYRKHSLIIREHEEGSEIYVSA 473

Query: 302 NGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481
            G +DV+  G     ++V ++  +  FGELA++YN PR AS+ A T   +W + R TFR 
Sbjct: 474 EGQYDVIRGG-----QLVASFGPATVFGELAILYNAPRQASIEAATDARVWKIARETFRA 528

Query: 482 ILLKSAFKKRK 514
           I+  S  ++R+
Sbjct: 529 IMQISGSRERE 539



 Score = 49.2 bits (112), Expect = 6e-05
 Identities = 30/114 (26%), Positives = 53/114 (46%), Gaps = 1/114 (0%)
 Frame = +2

Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316
           +R    + +R     +  D   + +V+D +  K  E    ++R+G+ G+ FY+I  G   
Sbjct: 537 EREENLQFLRSAPFLQEFDQSLLLKVVDLLQRKFYETDSCIVREGELGNEFYIIRCGTVT 596

Query: 317 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGA-LWAMDRHTF 475
           +    + + E++V   +    FGE AL+    R ASV A   G  +  +DR  F
Sbjct: 597 IKKLDEQQQEQIVANRKRGDYFGEQALLNADVRQASVYADAPGTEVLMLDREAF 650


>UniRef50_O76360 Cluster: Egg laying defective protein 4, isoform a;
           n=5; Caenorhabditis elegans|Rep: Egg laying defective
           protein 4, isoform a - Caenorhabditis elegans
          Length = 780

 Score = 68.9 bits (161), Expect = 6e-11
 Identities = 39/146 (26%), Positives = 73/146 (50%)
 Frame = +2

Query: 47  RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226
           +R    A + +P   ++       + K+   +  + +AV+     + L  +Q+ ++++ M
Sbjct: 158 QRAKKIAVSAEPTNFENKPATLQHYNKTVGAKQMIRDAVQKNDFLKQLAKEQIIELVNCM 217

Query: 227 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYN 406
           +E R+  G++VI++G+ GD  +V+  G   V      R   ++         GELA++YN
Sbjct: 218 YEMRARAGQWVIQEGEPGDRLFVVAEGELQV-----SREGALLGKMRAGTVMGELAILYN 272

Query: 407 MPRAASVRAQTAGALWAMDRHTFRRI 484
             R ASV+A T   LW +DR  F+ I
Sbjct: 273 CTRTASVQALTDVQLWVLDRSVFQMI 298



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 32/119 (26%), Positives = 62/119 (52%), Gaps = 2/119 (1%)
 Frame = +2

Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316
           + ++L   +  + +F++L   ++ ++ D M +   + G Y+IRQG+ GD F+VI +G   
Sbjct: 306 RHSQLMNFLTKVSIFQNLSEDRISKMADVMDQDYYDGGHYIIRQGEKGDAFFVINSGQVK 365

Query: 317 VLVTGDDRVE-KVVHTYEGSGSFGELALMYNMPRAASVRAQTAGA-LWAMDRHTFRRIL 487
           V    +   E + +        FGE AL+    R A++ AQ  G  +  +DR +F +++
Sbjct: 366 VTQQIEGETEPREIRVLNQGDFFGERALLGEEVRTANIIAQAPGVEVLTLDRESFGKLI 424


>UniRef50_O17474 Cluster: Cyclic GMP-dependent protein kinase; n=1;
           Hydra oligactis|Rep: Cyclic GMP-dependent protein kinase
           - Hydra oligactis (Hydra)
          Length = 742

 Score = 68.9 bits (161), Expect = 6e-11
 Identities = 48/162 (29%), Positives = 89/162 (54%)
 Frame = +2

Query: 29  VARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQ 208
           V    N+R +V AE+   E  + D   P + PKS   +  +++AV      + L+  Q++
Sbjct: 115 VKTVRNKRFAVSAES-GKELQNLD--FPKI-PKSTEVKEFISQAVLKNNFLKHLEECQVK 170

Query: 209 QVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGE 388
           +++  M +K  + GEY+I++GD G+  +V   G+ ++   GD  + K +   E    FGE
Sbjct: 171 EIVLFMSQKSFKRGEYIIKEGDMGNALFVSYVGLLEIS-QGDKILGKPLRPGE---LFGE 226

Query: 389 LALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
           LA++YN  R ASV+A     +W ++R+ F+ ++ K+   +R+
Sbjct: 227 LAILYNCTRTASVKAIDDVEVWYLERNVFQAVMQKTGIMRRE 268



 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 34/121 (28%), Positives = 66/121 (54%), Gaps = 3/121 (2%)
 Frame = +2

Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL--VTGD 334
           +  + +F++L    + ++++ + E+  E GE+++R+G+ GD+FY+++ G+  VL  + G 
Sbjct: 274 LHSVPVFKNLPNDTLLKIVEVIEEEFYEDGEFIVREGERGDSFYILKQGLVKVLQMIEGK 333

Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGA-LWAMDRHTFRRILLKSAFKKR 511
           D   ++ H  +G   FGE AL+    R ASV A   G     ++R  F   +   ++ K 
Sbjct: 334 DEPVEIRHLSQGE-YFGEKALLGEDVRTASVVASIGGVHCLVIERDVFMSFIGDLSYLKN 392

Query: 512 K 514
           K
Sbjct: 393 K 393


>UniRef50_A7C1J1 Cluster: Protein kinase, cGMP-dependent, type I;
           n=1; Beggiatoa sp. PS|Rep: Protein kinase,
           cGMP-dependent, type I - Beggiatoa sp. PS
          Length = 429

 Score = 68.5 bits (160), Expect = 8e-11
 Identities = 35/100 (35%), Positives = 59/100 (59%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
           LF  +  QQ+++++ ++  K+ +P E +IRQGDD    Y+IE G+F V +  D+R  +VV
Sbjct: 144 LFTYVPTQQLRRLVSSLKAKKLQPNEILIRQGDDAKEAYIIEKGLFTVQI--DERPNQVV 201

Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTF 475
            T       GE+AL+ N  R  +V AQT  +++ + +  F
Sbjct: 202 RTMIPGDLVGEIALVKNTKRTTNVIAQTRASVFVLPQPEF 241


>UniRef50_Q4QGD8 Cluster: Protein kinase A regulatory subunit,
           putative; n=7; Trypanosomatidae|Rep: Protein kinase A
           regulatory subunit, putative - Leishmania major
          Length = 502

 Score = 68.5 bits (160), Expect = 8e-11
 Identities = 48/158 (30%), Positives = 80/158 (50%), Gaps = 2/158 (1%)
 Frame = +2

Query: 47  RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226
           RR++V  E  DPE   +    P V  KS      + + +   +LF  L ++ +  V  AM
Sbjct: 203 RRQTVRVEGIDPEA--AKNYVPPVHEKSQEDTDMICKLLSHNVLFGFLGSKDILTVAGAM 260

Query: 227 FEKRSEPGEYVIRQGDDG-DNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403
           + +     E +I  G    D  YVI++G  DV+  G    +KV    EG+ + GEL L+Y
Sbjct: 261 YREEFVKDERIIEFGQTHCDKLYVIQSGEADVIKEG----QKVFVKTEGT-AVGELELLY 315

Query: 404 NMPRAASVRAQTAGAL-WAMDRHTFRRILLKSAFKKRK 514
           + P  A+V+  T   + W +DR T+R +++ S  ++R+
Sbjct: 316 DTPAVATVKVSTEVLVAWVLDRETYRNLVMGSCIRRRE 353



 Score = 41.1 bits (92), Expect = 0.015
 Identities = 24/98 (24%), Positives = 42/98 (42%)
 Frame = +2

Query: 182 RSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHT 361
           +SLDA +  Q+ DA+       G+Y+I   ++G+  Y+I  G  +V+       +  V  
Sbjct: 366 QSLDAYERMQIADALTSDEFAAGDYIIHYDEEGEWLYIIIEGTVEVIGRDAAGNKTKVCE 425

Query: 362 YEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTF 475
           +      GEL  +      A + A T      ++R  F
Sbjct: 426 FHSGDHIGELEFLNKHRTVADIVAVTGVTTAKLNRRHF 463


>UniRef50_Q23DN8 Cluster: Cyclic nucleotide-binding domain
           containing protein; n=1; Tetrahymena thermophila
           SB210|Rep: Cyclic nucleotide-binding domain containing
           protein - Tetrahymena thermophila SB210
          Length = 808

 Score = 68.1 bits (159), Expect = 1e-10
 Identities = 35/96 (36%), Positives = 56/96 (58%)
 Frame = +2

Query: 194 AQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGS 373
           AQ+++  +  MF       +++ +Q D+  +F+++E G  +V+V      EK     +  
Sbjct: 92  AQRVELTIK-MFYCEVPMNDFIFKQSDNATSFFILERGAMEVIVN-----EKSKRELKAG 145

Query: 374 GSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481
             FGELAL+YN PR+ASV+A     LW +DR+TFRR
Sbjct: 146 DGFGELALLYNAPRSASVKALDHCYLWGIDRNTFRR 181



 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 35/121 (28%), Positives = 58/121 (47%)
 Frame = +2

Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 304
           K   +  +  E VR    F +L  +Q   +   +  ++    + ++ +GD   +FY+I+ 
Sbjct: 189 KEYEENRKFMEVVR---FFHNLTNEQKDAIAAVLIVQKFYKNQVIVTEGDPASSFYIIKE 245

Query: 305 GVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484
           G   V   G+  V K+   Y+G  SFGE AL YN  R  +VRA+      A+ R T  ++
Sbjct: 246 GNVTVW-KGNKEVRKL---YKGD-SFGEQALYYNTVRQMTVRAEDEVKCLALGRDTLTKV 300

Query: 485 L 487
           L
Sbjct: 301 L 301


>UniRef50_Q4QF64 Cluster: Protein kinase, putative; n=2;
           Leishmania|Rep: Protein kinase, putative - Leishmania
           major
          Length = 2689

 Score = 67.7 bits (158), Expect = 1e-10
 Identities = 51/173 (29%), Positives = 82/173 (47%), Gaps = 9/173 (5%)
 Frame = +2

Query: 23  PPVARFNNRRKSVFAETYDPEEDDSDEGAPA-------VFPKSDAQRARLAEAVRGILLF 181
           P   +   RR +V A    P  +   E +PA       V PKS A+  +L   +R    F
Sbjct: 301 PTGGQCQGRRLAVSAAPCMPPPEIIGEDSPATALPPLRVVPKSPAEEQQLRRLLRRCHSF 360

Query: 182 RSLDAQQMQQVLDAMFEKRSEPGEYVIRQGD-DGDNFYVIENGVFDVLVTGDDRVEKVVH 358
            SL+A  ++ VL AM ++    G  ++ QG    +  Y++  G  + +  G     K + 
Sbjct: 361 SSLEADTLESVLKAMDKEVHAAGAAILEQGQATTEKLYLVGEGTCEAIKNG-----KSLG 415

Query: 359 TYEGSGSFGELALMYNMPR-AASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
             +  G+FGEL LMY     AA+VR  T   L+ +D  ++ R ++ SA +KR+
Sbjct: 416 PLQPGGTFGELELMYKQAMCAATVRCVTRCVLYTLDEASYHRAVMTSALQKRR 468


>UniRef50_A0BE58 Cluster: Chromosome undetermined scaffold_101,
           whole genome shotgun sequence; n=17;
           Oligohymenophorea|Rep: Chromosome undetermined
           scaffold_101, whole genome shotgun sequence - Paramecium
           tetraurelia
          Length = 823

 Score = 66.9 bits (156), Expect = 3e-10
 Identities = 33/91 (36%), Positives = 55/91 (60%)
 Frame = +2

Query: 206 QQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFG 385
           + ++  MF  R    E+V +Q D    +++I+ GV ++++ G+  V+K + T +G   FG
Sbjct: 135 EDIVMKMFYCRVAGNEFVFQQNDQASAYFIIDQGVCEIIINGE--VKKQLSTGDG---FG 189

Query: 386 ELALMYNMPRAASVRAQTAGALWAMDRHTFR 478
           ELAL+Y  PR+ASV+ +     W +DR TFR
Sbjct: 190 ELALLYGAPRSASVKTKDECFFWCIDRGTFR 220



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 27/110 (24%), Positives = 52/110 (47%), Gaps = 1/110 (0%)
 Frame = +2

Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
           +  I  F  +   Q   +  A+  ++ + G+ ++ +GD   ++++I++G+  ++  G++ 
Sbjct: 238 IDSIKFFEWMTVDQKDMIAGAIIAQQFKKGQAIVNEGDMASSYFIIKSGMVKIMKGGNE- 296

Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAG-ALWAMDRHTFRRIL 487
               +       SFGE AL  N  R ASV A        A+ R T  +IL
Sbjct: 297 ----LRQMSAGDSFGEQALYQNSVRGASVIAVDENVCCLAIGRETITKIL 342


>UniRef50_A4S6U9 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 680

 Score = 66.1 bits (154), Expect = 4e-10
 Identities = 38/111 (34%), Positives = 57/111 (51%)
 Frame = +2

Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 328
           L EA+     F  LDA   ++V   MF      G  ++ + + GD  Y+I  G FDVL  
Sbjct: 16  LCEALSQTFTFSELDANVRRRVASEMFFINVPEGTILMEEDEPGDALYLIAGGEFDVLQN 75

Query: 329 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481
                  V+   +G    GELAL+Y++PR+A+VRA+T   +W   +  F+R
Sbjct: 76  RLGADISVLTRTKGD-IIGELALLYSVPRSATVRAKTRSQVWVCTQQVFKR 125


>UniRef50_Q01E02 Cluster: CGMP-dependent protein kinase, putative;
           n=2; Ostreococcus|Rep: CGMP-dependent protein kinase,
           putative - Ostreococcus tauri
          Length = 935

 Score = 61.3 bits (142), Expect = 1e-08
 Identities = 40/104 (38%), Positives = 55/104 (52%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
           LF +L  QQ+  + +A   +  E  + V RQGD G  FY+IE G   V V G     +VV
Sbjct: 248 LFNALSEQQLITISNAARRETYEARDEVFRQGDPGHCFYIIERGEVSVRVNG----AEVV 303

Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
               G   FGE AL+ N PRAA++ A T  +   ++R TF  +L
Sbjct: 304 KLSRGD-FFGERALVNNEPRAATIYAMTEVSCLVLNRQTFVSML 346



 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 33/123 (26%), Positives = 58/123 (47%), Gaps = 5/123 (4%)
 Frame = +2

Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG---VFDVLV 325
           E +  + +   L  +++Q + + + +      E VI+QG+ GD  +++E+G   V D   
Sbjct: 477 ETLSKVPILSKLSPEEIQNLAEELTDVSFRANETVIKQGESGDAMFILESGEVEVIDEKT 536

Query: 326 TGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL--LKSA 499
                  K++     S  FGEL L+ + PRAA+VR      +  + R  F + L  LK  
Sbjct: 537 LNTSGDPKLLCKLGPSSYFGELGLLNSDPRAATVRVPNRATVLVITRRVFEQHLGSLKEI 596

Query: 500 FKK 508
            K+
Sbjct: 597 LKR 599



 Score = 45.6 bits (103), Expect(2) = 5e-10
 Identities = 25/67 (37%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
 Frame = +2

Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDG-DNFYVIE 301
           ++ A    +  A+ G LLF  LDA   ++V DAM        + VI QGDD  + FY+IE
Sbjct: 78  RTTASEQAIERAMEGNLLFAELDAASRRRVADAMMPMYVGENDVVIAQGDDECERFYIIE 137

Query: 302 NGVFDVL 322
           +G   V+
Sbjct: 138 SGEASVM 144



 Score = 40.3 bits (90), Expect(2) = 5e-10
 Identities = 24/64 (37%), Positives = 32/64 (50%)
 Frame = +2

Query: 323 VTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAF 502
           V  D      V T      FGELAL+Y  PR+A++ AQT   LW +    F+ I  K + 
Sbjct: 174 VVYDPATATCVATLGPGRGFGELALLYACPRSATIVAQTPMKLWTLHSSAFKAI--KHSV 231

Query: 503 KKRK 514
            KR+
Sbjct: 232 AKRE 235


>UniRef50_Q8MMZ5 Cluster: CGMP-dependent protein kinase; n=2;
           Eimeria|Rep: CGMP-dependent protein kinase - Eimeria
           maxima
          Length = 1007

 Score = 65.7 bits (153), Expect = 6e-10
 Identities = 35/122 (28%), Positives = 69/122 (56%), Gaps = 1/122 (0%)
 Frame = +2

Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 304
           K+D+  + +  ++ G L+  SL+  +++ + +A+       G+ V +QG++G  F+++ +
Sbjct: 164 KTDSDLSLIRSSLSGNLVCSSLNDSEVEALANAVQFFTFAKGDIVTKQGENGSYFFIVHS 223

Query: 305 GVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA-QTAGALWAMDRHTFRR 481
           G F+V+V      EKVV+      +FGE++L++N  R A+++      ALW + R  FR 
Sbjct: 224 GEFEVIVN-----EKVVNKIVQGQAFGEISLIHNSARTATIKTLSDQAALWGVQRQVFRE 278

Query: 482 IL 487
            L
Sbjct: 279 TL 280



 Score = 55.2 bits (127), Expect = 8e-07
 Identities = 35/105 (33%), Positives = 56/105 (53%), Gaps = 1/105 (0%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
           +FR L  QQ Q ++ A    R   GE +IR+G+ G  F++I+ G   +L  G     + V
Sbjct: 574 IFRYLSEQQTQTLIRAFKTVRYTQGEAIIREGEIGSRFFIIKLGEVAILKGG-----RRV 628

Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGA-LWAMDRHTFRRIL 487
            T      FGE AL+++  R+A+V A +    LW +D+  F +I+
Sbjct: 629 RTLGRHDYFGERALLHDERRSATVAANSPEVDLWVVDKDVFLQIV 673



 Score = 54.4 bits (125), Expect = 1e-06
 Identities = 29/103 (28%), Positives = 55/103 (53%)
 Frame = +2

Query: 179 FRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVH 358
           F+ L   Q   + +A+  +  +PG+ ++++G+ GD  Y+I++G   V + G D     V 
Sbjct: 301 FQMLTEAQKNVITNALVVQSFKPGQPIVKEGEKGDILYIIKSGKARVSIKGKD-----VR 355

Query: 359 TYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
             +    FGE AL+Y+ PR+A++ A+      ++ R    R+L
Sbjct: 356 LLQKGDYFGERALLYDEPRSATITAEEETICVSIGRDLLDRVL 398


>UniRef50_Q4Q2R2 Cluster: Regulatory subunit of protein kinase
           a-like protein; n=3; Leishmania|Rep: Regulatory subunit
           of protein kinase a-like protein - Leishmania major
          Length = 648

 Score = 65.3 bits (152), Expect = 8e-10
 Identities = 38/144 (26%), Positives = 74/144 (51%), Gaps = 3/144 (2%)
 Frame = +2

Query: 92  DSDEGAPAVFPKSDAQRARLAEAVRGIL---LFRSLDAQQMQQVLDAMFEKRSEPGEYVI 262
           D DE   A FP +   + ++    R ++   LF +LD   + +    M  ++ E G  ++
Sbjct: 335 DIDEARIASFPTTPKSQEKMKTISRVLVRHFLFSTLDDSDIAKFASIMDVEKFEAGTQIL 394

Query: 263 RQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTA 442
            +G   D F+++ +G  +  +  +D  E VV    GS +FG+L LMY +   A+V A+++
Sbjct: 395 EKGHTNDTFFIVLDGEAETTMMNEDGAEVVVPLVRGS-TFGDLGLMYEISNGAAVVARSS 453

Query: 443 GALWAMDRHTFRRILLKSAFKKRK 514
               +++R T++ I  ++   KR+
Sbjct: 454 VQCASLERRTYKMITSRAMEDKRR 477


>UniRef50_A0E0G1 Cluster: Chromosome undetermined scaffold_71, whole
           genome shotgun sequence; n=5; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_71,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 779

 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 34/102 (33%), Positives = 55/102 (53%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
           +F  LD     ++++ M+   S+  E+V +QGD    F++IE G   + +      E+  
Sbjct: 94  MFAQLDNNDKAKLIEEMYYVTSKDQEFVFKQGDKATLFFIIERGQCQITIN-----EEKK 148

Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481
              + S  FGELALMY+ PR+ASV A      W ++R+ FR+
Sbjct: 149 RVLKPSEFFGELALMYHAPRSASVIAIGDCGFWVLERYKFRK 190



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 28/112 (25%), Positives = 51/112 (45%), Gaps = 1/112 (0%)
 Frame = +2

Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
           E +  +  F  +  +Q   + + +   + + GE ++ +GD  ++FY+I+ G   V   G 
Sbjct: 205 EFLAQVKFFDFMTEEQRDSIANVLITLKFKQGESIVNEGDMANSFYIIQKGTVQVTKQG- 263

Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGA-LWAMDRHTFRRIL 487
               + +       SFGE AL  N  R A+V+A  +   L ++ R     IL
Sbjct: 264 ----QFLRYMNQGDSFGEQALFGNCVRGATVKAHDSDVNLLSLSREDITTIL 311


>UniRef50_Q2HGG6 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 345

 Score = 63.7 bits (148), Expect = 2e-09
 Identities = 40/125 (32%), Positives = 68/125 (54%), Gaps = 1/125 (0%)
 Frame = +2

Query: 116 VFPKSDAQRARLAEA-VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFY 292
           +  +S   R R+ E  +  + L  +L   +  ++ DA+  ++   G  +IR+GD G +FY
Sbjct: 196 ILMESTFARRRMYEGFLEEVPLLSTLTPYERSKIADALESQKFPAGHTIIREGDPGHSFY 255

Query: 293 VIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHT 472
           ++E G      +G+D    V H Y+    FGELAL+ + PRAASV +QT   +  + +  
Sbjct: 256 LLEAGEAVAYRSGND--TPVKH-YKKGDFFGELALLNDAPRAASVVSQTEVKVARLGKSA 312

Query: 473 FRRIL 487
           F+R+L
Sbjct: 313 FQRLL 317



 Score = 37.5 bits (83), Expect = 0.18
 Identities = 16/33 (48%), Positives = 23/33 (69%)
 Frame = +2

Query: 416 AASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
           A  + A+    LWA+DR TFRRIL++S F +R+
Sbjct: 174 ATVISAEPQCMLWALDRVTFRRILMESTFARRR 206


>UniRef50_A0YP22 Cluster: Putative uncharacterized protein; n=1;
           Lyngbya sp. PCC 8106|Rep: Putative uncharacterized
           protein - Lyngbya sp. PCC 8106
          Length = 478

 Score = 63.3 bits (147), Expect = 3e-09
 Identities = 28/113 (24%), Positives = 66/113 (58%)
 Frame = +2

Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 328
           L + ++ +  F++ +   ++Q+++  + K+ +  E+++R+G+ G+ FY+I +G  +  + 
Sbjct: 311 LKDILKKVCYFKTCNDFHLRQLIELGYRKQFQASEFILREGETGERFYIILSGSVEAYLE 370

Query: 329 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
             DR   V++T+     FGE +LM  +P+ AS+R+     L+ + +H F+  +
Sbjct: 371 KVDRQIDVLNTH---NFFGEFSLMLGVPQPASIRSLEETTLFIIPKHNFQTFI 420


>UniRef50_Q4CSS9 Cluster: Protein kinase, putative; n=2; Trypanosoma
           cruzi|Rep: Protein kinase, putative - Trypanosoma cruzi
          Length = 922

 Score = 62.5 bits (145), Expect = 6e-09
 Identities = 38/138 (27%), Positives = 71/138 (51%), Gaps = 2/138 (1%)
 Frame = +2

Query: 107 APAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQ-GDDGD 283
           +P V  KS  +   +   V    LF ++D +    ++ A+       G  ++RQ G   +
Sbjct: 208 SPPVVAKSPEEERIVRAGVMACHLFSNMDNKDQSIIVQALKRVTFPAGTDILRQDGASVE 267

Query: 284 NFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPR-AASVRAQTAGALWAM 460
             +++  G  DV+  G     K VHT     +FGE+ +MYN+P   A++R+ T   L+ +
Sbjct: 268 KLFLLTQGSCDVIKNG-----KRVHTLLECSTFGEMEMMYNLPTCVATIRSVTNCVLYTL 322

Query: 461 DRHTFRRILLKSAFKKRK 514
           D++T++ I+L ++  KR+
Sbjct: 323 DQYTYQNIVLAASLHKRE 340



 Score = 34.7 bits (76), Expect = 1.3
 Identities = 23/99 (23%), Positives = 42/99 (42%)
 Frame = +2

Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316
           +R +    +  +   R        Q+ +A+  K    G+Y+IR G+ G   ++I  G   
Sbjct: 338 KREKYEALLSNVQFLREFSDYDRMQIAEALVTKTYRQGDYIIRFGETGKWMHIIVEGEVA 397

Query: 317 VLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 433
           V+     +  +++   EG    GEL  ++N    A V A
Sbjct: 398 VVGRHIGKKCEILRLKEGE-VVGELEFLFNDLTVADVIA 435


>UniRef50_Q0LLK2 Cluster: Stage II sporulation E; n=1; Herpetosiphon
           aurantiacus ATCC 23779|Rep: Stage II sporulation E -
           Herpetosiphon aurantiacus ATCC 23779
          Length = 570

 Score = 62.1 bits (144), Expect = 7e-09
 Identities = 37/108 (34%), Positives = 57/108 (52%)
 Frame = +2

Query: 128 SDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG 307
           ++A  A L E +  + LF  +D   +Q ++ +    R  PGE +  +GD GD+ Y++  G
Sbjct: 142 TEASIAPLVEFLEQLPLFHEVDQATIQNLVQSAEHVRLAPGETLFSEGDSGDDCYIVMAG 201

Query: 308 VFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGAL 451
             DV+         +     G+   GE+AL+ N PRAASVRA+TA  L
Sbjct: 202 DVDVIKALATETILLERCRPGA-ILGEMALIDNSPRAASVRARTAATL 248


>UniRef50_UPI0000660D74 Cluster: Homolog of Homo sapiens
           "cGMP-dependent protein kinase 2; n=3; Coelomata|Rep:
           Homolog of Homo sapiens "cGMP-dependent protein kinase 2
           - Takifugu rubripes
          Length = 93

 Score = 61.7 bits (143), Expect = 1e-08
 Identities = 31/92 (33%), Positives = 51/92 (55%)
 Frame = +2

Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
           +A+        L+ Q M Q++D MFE     G+ VIR+G+ G+  YV+  G+ +V+  G 
Sbjct: 6   DAIMNNDFLNKLEPQHMNQMVDCMFENVYTEGQLVIREGEPGNYLYVLSEGLLEVIQNG- 64

Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVR 430
               K++       +FGELA++YN  R A+V+
Sbjct: 65  ----KLLGEMHAGTAFGELAILYNCKRTATVK 92


>UniRef50_Q8DKN0 Cluster: Tlr0829 protein; n=1; Synechococcus
           elongatus|Rep: Tlr0829 protein - Synechococcus elongatus
           (Thermosynechococcus elongatus)
          Length = 594

 Score = 61.7 bits (143), Expect = 1e-08
 Identities = 40/128 (31%), Positives = 67/128 (52%), Gaps = 1/128 (0%)
 Frame = +2

Query: 107 APAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDN 286
           APA  P+       L   +R I  F      ++Q +++    +    GE + R+GD GD 
Sbjct: 421 APAA-PEMAKAEPSLTNLLRNISCFSRCSNAELQMLIELGNREFYTVGEVICREGDPGDA 479

Query: 287 FYVIENGVFDVLVTGDDRVEKVVHT-YEGSGSFGELALMYNMPRAASVRAQTAGALWAMD 463
           FY+I  G  +V     +++ +++ T YEG   FGE+A++  MPR+A+VRA     L+ + 
Sbjct: 480 FYIILEGSVEV---RSEQLNQILATLYEGE-FFGEIAVLTGMPRSATVRALEETVLFVVH 535

Query: 464 RHTFRRIL 487
           R   +R+L
Sbjct: 536 RAAVQRLL 543


>UniRef50_A5GVU5 Cluster: ABC-type multidrug transport system,
           ATPase and permease components; n=1; Synechococcus sp.
           RCC307|Rep: ABC-type multidrug transport system, ATPase
           and permease components - Synechococcus sp. (strain
           RCC307)
          Length = 718

 Score = 61.7 bits (143), Expect = 1e-08
 Identities = 41/127 (32%), Positives = 66/127 (51%), Gaps = 4/127 (3%)
 Frame = +2

Query: 119 FPKSDAQRARL-AEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYV 295
           F  S + R R+ A+ +  I LF  ++   ++ +      +R  PGE V R+GD  D+FYV
Sbjct: 576 FDISASHRVRITADRLASIPLFHGVEKAVLRWLAAEFVSERVRPGEEVFREGDPPDSFYV 635

Query: 296 IENGVFDVL---VTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDR 466
           +  G  +VL   + G   +++ V   E    FG+  L+ + PRA +VRA+  G L  +DR
Sbjct: 636 VVAGTLEVLQDDLWGGVPIKQGV--VEEGDFFGDAGLLEDRPRAVTVRARGEGLLLRLDR 693

Query: 467 HTFRRIL 487
             F  +L
Sbjct: 694 DRFLDLL 700


>UniRef50_A3IKE0 Cluster: Putative uncharacterized protein; n=1;
           Cyanothece sp. CCY 0110|Rep: Putative uncharacterized
           protein - Cyanothece sp. CCY 0110
          Length = 493

 Score = 61.7 bits (143), Expect = 1e-08
 Identities = 34/113 (30%), Positives = 64/113 (56%)
 Frame = +2

Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 328
           + E +  +  F++LD  Q++++++    K  +  E + ++ D GD FY+I +G  ++   
Sbjct: 327 IKELLSKVEYFKTLDDLQIRKLIEIGTLKELKQNEILFKENDPGDAFYIILSGSVEIFTE 386

Query: 329 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
             ++   ++  Y G   FGELALM  +PR ASV+AQ    L++++   F R+L
Sbjct: 387 TLNKTLAIL--YRGD-FFGELALMLGIPRTASVKAQQETILFSINNQQFDRLL 436


>UniRef50_Q4SL71 Cluster: Chromosome 17 SCAF14563, whole genome
           shotgun sequence; n=4; Tetraodontidae|Rep: Chromosome 17
           SCAF14563, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 726

 Score = 59.3 bits (137), Expect = 5e-08
 Identities = 36/112 (32%), Positives = 54/112 (48%), Gaps = 1/112 (0%)
 Frame = +2

Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
           E ++ +  F+ L    + ++ D + E   E GEY+IRQG  GD F++I  G  +V     
Sbjct: 269 EFLKSVPTFQGLQEDILSKLADVLEETHYEDGEYIIRQGARGDTFFIISKGKVNVTREDS 328

Query: 335 DRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
              E V     G G  FGE AL     R A+V A  A     +DR +F+ ++
Sbjct: 329 PNGEPVYLRSLGKGDWFGEKALQGEDIRTANVIAAEAVTCLVIDRDSFKHLI 380



 Score = 56.0 bits (129), Expect(2) = 1e-08
 Identities = 36/130 (27%), Positives = 65/130 (50%), Gaps = 1/130 (0%)
 Frame = +2

Query: 47  RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226
           +R+++ AE    +  D        +PKS   +  + EA+      ++L+  Q+Q+++D M
Sbjct: 73  KRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCM 132

Query: 227 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMY 403
           +         +I++GD G   YV+E+G  +V        E +     G G  FGELA++Y
Sbjct: 133 YPVEYGKDSCIIKEGDVGSLVYVMEDGKVEV------TKESLKLCTMGPGKVFGELAILY 186

Query: 404 NMPRAASVRA 433
           N  R A+V++
Sbjct: 187 NCTRTATVKS 196



 Score = 25.4 bits (53), Expect(2) = 1e-08
 Identities = 10/28 (35%), Positives = 18/28 (64%)
 Frame = +2

Query: 425 VRAQTAGALWAMDRHTFRRILLKSAFKK 508
           V++ T   LWA+DR  F+ I++++   K
Sbjct: 236 VKSLTNVKLWAIDRQCFQTIMMRTGLIK 263


>UniRef50_Q8SRB5 Cluster: CAMP-DEPENDENT PROTEIN KINASE TYPE 1
           REGULATORY CHAIN; n=1; Encephalitozoon cuniculi|Rep:
           CAMP-DEPENDENT PROTEIN KINASE TYPE 1 REGULATORY CHAIN -
           Encephalitozoon cuniculi
          Length = 312

 Score = 61.3 bits (142), Expect = 1e-08
 Identities = 40/157 (25%), Positives = 81/157 (51%)
 Frame = +2

Query: 44  NRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDA 223
           +RR  V++E   PE    +      +PK +     L+  +   + F  L+ +Q  +++++
Sbjct: 79  SRRSGVYSERITPETFRLN-----YYPKDEETIRFLSSILVSDIPFGFLNPEQKTRLIES 133

Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403
                 + G +V+ +G+ G   Y++ +G F+V   G   + K+    +G   FGE+AL++
Sbjct: 134 TELIEIKRGTFVMHEGEIGSQMYIVASGEFEV-TKGGTLLRKLT---KGC-FFGEIALLH 188

Query: 404 NMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
           N+PR A+V+A T G +W +++ +F  I +      +K
Sbjct: 189 NIPRTATVKAVTDGKVWVVEQTSFSGIRMVDRILNKK 225


>UniRef50_Q1D8K7 Cluster: Mechanosensitive ion channel/cyclic
           nucleotide-binding domain protein; n=2;
           Cystobacterineae|Rep: Mechanosensitive ion
           channel/cyclic nucleotide-binding domain protein -
           Myxococcus xanthus (strain DK 1622)
          Length = 525

 Score = 60.9 bits (141), Expect = 2e-08
 Identities = 44/129 (34%), Positives = 69/129 (53%), Gaps = 6/129 (4%)
 Frame = +2

Query: 116 VFPKSDAQRARLAE-AVRGIL----LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDG 280
           V  + +  R  L+E  +R +L    LF+SLD +++ ++      +R   GE +I++GD+G
Sbjct: 343 VHVRQEMARTELSEDTIRSLLGAVDLFQSLDTEELDRLRQESLVRRFGAGERIIQEGDEG 402

Query: 281 DNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWA 457
             FYV+ +G   V  TG  + E    T  G GS FGE+ L+    R+A+V A     L  
Sbjct: 403 RTFYVLASGEVSVR-TGKSQSEV---TRLGRGSYFGEMCLLTGERRSATVVAVEDSLLLE 458

Query: 458 MDRHTFRRI 484
           +DR TF R+
Sbjct: 459 VDRPTFARL 467


>UniRef50_A4TWF8 Cluster: Na+/H+ Antiporter; n=1; Magnetospirillum
            gryphiswaldense|Rep: Na+/H+ Antiporter - Magnetospirillum
            gryphiswaldense
          Length = 868

 Score = 60.9 bits (141), Expect = 2e-08
 Identities = 36/114 (31%), Positives = 64/114 (56%), Gaps = 1/114 (0%)
 Frame = +2

Query: 161  VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
            V G+ LF++L  +Q+ +++D +    + PG+++IR+G+ GD  + + +G  +V  T  +R
Sbjct: 730  VEGVPLFKTLSPEQLSRIIDLLHPMLAVPGDFIIRKGEVGDGMFFVASGAVEVR-TETNR 788

Query: 341  VEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSA 499
            + +      GSG  FGE+AL+ + PR A V A    +L  +    F  +L  SA
Sbjct: 789  LRR------GSGDFFGEMALLSHAPRNADVVALGFCSLLVLHARDFSALLNTSA 836


>UniRef50_Q9M8S6 Cluster: Potassium channel SKOR (Stelar K(+)
           outward rectifying channel); n=25; Magnoliophyta|Rep:
           Potassium channel SKOR (Stelar K(+) outward rectifying
           channel) - Arabidopsis thaliana (Mouse-ear cress)
          Length = 828

 Score = 59.3 bits (137), Expect = 5e-08
 Identities = 29/109 (26%), Positives = 58/109 (53%)
 Frame = +2

Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
           +  + LFR   ++ + Q++  + E+   PGE ++ QG   D  Y + +GV + +    D 
Sbjct: 398 IEKVPLFRGCSSEFINQIVIRLHEEFFLPGEVIMEQGSVVDQLYFVCHGVLEEIGITKDG 457

Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
            E++V   +   SFGE++++ N+P+  +VR      +  +D+ +F  IL
Sbjct: 458 SEEIVAVLQPDHSFGEISILCNIPQPYTVRVAELCRILRLDKQSFMNIL 506


>UniRef50_Q8CXT1 Cluster: CAMP-dependent protein kinase regulatory
           chain; n=4; Leptospira|Rep: CAMP-dependent protein
           kinase regulatory chain - Leptospira interrogans
          Length = 719

 Score = 58.8 bits (136), Expect = 7e-08
 Identities = 36/134 (26%), Positives = 68/134 (50%), Gaps = 2/134 (1%)
 Frame = +2

Query: 110 PAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNF 289
           P + P    +   L + +  I +F     ++ ++ L  + E+R + G+ +IR+G  GD F
Sbjct: 450 PEITPPKHIEAYNLLDVLTQIDIFHGFPIEKAKEFLLIVNEERYKRGDQIIRKGTPGDKF 509

Query: 290 YVIENG--VFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMD 463
           Y+I +G   F+ L   D+  +  +  Y     FGE +L+ ++PRAA V A+T      ++
Sbjct: 510 YIIASGNVKFEGL-NQDETGQGPIKRYGTYEYFGEASLVLDLPRAADVYAETDVLALTIE 568

Query: 464 RHTFRRILLKSAFK 505
           ++ F + +  S  K
Sbjct: 569 KNKFLQFIRNSDLK 582


>UniRef50_Q2VWB6 Cluster: CAMP-dependent protein kinase A regulatory
           subunit; n=2; Giardia intestinalis|Rep: CAMP-dependent
           protein kinase A regulatory subunit - Giardia lamblia
           (Giardia intestinalis)
          Length = 460

 Score = 58.8 bits (136), Expect = 7e-08
 Identities = 39/130 (30%), Positives = 70/130 (53%), Gaps = 2/130 (1%)
 Frame = +2

Query: 131 DAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGV 310
           +A+  R    +R + + + L   ++  +  A   +    G+ ++ QGD+G+ FY IE+G 
Sbjct: 335 EAEIQRYIGFLRHVEVLKQLRENELFALAQACTPEYYIDGQDIVTQGDEGNTFYFIEDGR 394

Query: 311 FDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL- 487
            DV+V+ D +V ++      +  FGE AL+ N PR A+ R+     + A+DR +F  +L 
Sbjct: 395 VDVIVS-DHKVAEL----SSNSYFGEAALLNNAPRNATCRSVGETKVAALDRESFDNLLG 449

Query: 488 -LKSAFKKRK 514
            LKS  ++ K
Sbjct: 450 PLKSILERPK 459



 Score = 38.7 bits (86), Expect = 0.078
 Identities = 36/141 (25%), Positives = 66/141 (46%), Gaps = 20/141 (14%)
 Frame = +2

Query: 116 VFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEP-GEYVIRQGDDGDNFY 292
           V  K+  + A + +A+    L  +  ++ ++Q L ++ +    P G  +I+QGD GD FY
Sbjct: 188 VLEKTPEETALILKALNSSALTETY-SRDVKQALASVLKLIDCPMGTVLIKQGDPGDYFY 246

Query: 293 VIENGVFDVLVTGD----------------DRVEKV---VHTYEGSGSFGELALMYNMPR 415
           +++ G  ++  T +                + V+K+   V+        G+LAL+Y  PR
Sbjct: 247 IMKTGHCNIYKTENVPPETVSVPDNTLDPAECVQKLGPQVNEVLPGVGVGDLALLYGAPR 306

Query: 416 AASVRAQTAGALWAMDRHTFR 478
           AA+V      + WA+    FR
Sbjct: 307 AATVITTVESSFWAIHGTDFR 327


>UniRef50_Q5QFC4 Cluster: EnvDll2-01; n=1; Oikopleura dioica|Rep:
           EnvDll2-01 - Oikopleura dioica (Tunicate)
          Length = 703

 Score = 58.4 bits (135), Expect = 9e-08
 Identities = 33/101 (32%), Positives = 55/101 (54%), Gaps = 1/101 (0%)
 Frame = +2

Query: 188 LDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYE 367
           L    ++++ D + E+R +  + +I+QG+ GDNFY+I  G   + V  D   EK V   +
Sbjct: 280 LKESNLRKIADCLEEERFDDKDPIIKQGEVGDNFYIIRTGSVRITVNTDGDEEKEV-AVK 338

Query: 368 GSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
           G G  FGE AL+ +  R+A+V A      + +DR  F  ++
Sbjct: 339 GEGEFFGEKALLTSDTRSANVYAVGDVVCYTLDRSAFTNLI 379



 Score = 58.0 bits (134), Expect = 1e-07
 Identities = 39/131 (29%), Positives = 67/131 (51%), Gaps = 3/131 (2%)
 Frame = +2

Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVI--RQGDDGDNFYVI 298
           K+  QR  + +A+      R L   Q+  ++DAM +      E +I  R+   GD  ++I
Sbjct: 140 KTAEQRKLIKDALLKNSFMRGLSEDQLNMLIDAMSKIDYPATEKIIKDRENTTGDEMFII 199

Query: 299 ENGVFDVLVTGDDRVEKVVHTYE-GSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTF 475
           E+G  +V ++ D       H  +  SG FGELA+MYN  R A++ ++T   LW + R  F
Sbjct: 200 EDG--EVTISKDG-----THITDIKSGLFGELAIMYNCQRTATITSKTDVTLWKLHRTAF 252

Query: 476 RRILLKSAFKK 508
           + ++  +  +K
Sbjct: 253 QTVVKAAGEEK 263


>UniRef50_A7C147 Cluster: cGMP-dependent protein kinase type I; n=1;
           Beggiatoa sp. PS|Rep: cGMP-dependent protein kinase type
           I - Beggiatoa sp. PS
          Length = 387

 Score = 58.0 bits (134), Expect = 1e-07
 Identities = 36/118 (30%), Positives = 64/118 (54%), Gaps = 2/118 (1%)
 Frame = +2

Query: 146 RLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV 325
           R  + +R     R L A+ + + +  M   +++ GE ++R+G+ GD FY+I++G  ++  
Sbjct: 131 RRMDKLRHFPALRRLPAESIYEAVHRMKIIKAKAGEIIVREGELGDAFYLIDSGRVEIWQ 190

Query: 326 TG--DDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLK 493
           TG  DD+  +V    EG  +FGE AL+    R A+VR    G L  +++  F  ++ K
Sbjct: 191 TGFYDDKPTRVTELGEGD-AFGEDALVTGGRRNATVRMIEEGQLLILEQSDFIELISK 247


>UniRef50_A3YU60 Cluster: Putative glutaminase; n=1; Synechococcus
           sp. WH 5701|Rep: Putative glutaminase - Synechococcus
           sp. WH 5701
          Length = 620

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 4/100 (4%)
 Frame = +2

Query: 188 LDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT--GDD--RVEKVV 355
           L     Q + D M  +    GE+V+++GD G   +++  G F + V   G D       +
Sbjct: 482 LQPTHRQTLADLMQCRNFAKGEHVVKKGDPGHELFLVREGRFTITVELRGSDGQTYASRL 541

Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTF 475
            T+E    FGE+A +   PR A+V A   G+ W ++RH F
Sbjct: 542 ATFEPGMCFGEIAFLSGTPRTANVTADLDGSCWVLERHDF 581


>UniRef50_Q10V66 Cluster: Cyclic nucleotide-binding protein; n=2;
           Oscillatoriales|Rep: Cyclic nucleotide-binding protein -
           Trichodesmium erythraeum (strain IMS101)
          Length = 454

 Score = 57.2 bits (132), Expect = 2e-07
 Identities = 28/111 (25%), Positives = 60/111 (54%)
 Frame = +2

Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
           E +  + +F+   +  +++++ A+  +   P EY+IR+G+ G+  Y I+ G+  V     
Sbjct: 323 EVIEKVPIFQGSTSHFVEEIVIALKPEIVPPNEYIIREGNLGNEMYFIKRGLVQVF---S 379

Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
           ++   +  T E    FGE++L+Y   R AS+   T   L+ + ++ F+++L
Sbjct: 380 EKTGSIYRTMEAGTFFGEISLVYEKRRTASIITLTYCELFILYKNDFKKVL 430


>UniRef50_Q9Y3Q4 Cluster: Potassium/sodium
           hyperpolarization-activated cyclic nucleotide-gated
           channel 4; n=41; Euteleostomi|Rep: Potassium/sodium
           hyperpolarization-activated cyclic nucleotide-gated
           channel 4 - Homo sapiens (Human)
          Length = 1203

 Score = 57.2 bits (132), Expect = 2e-07
 Identities = 35/117 (29%), Positives = 58/117 (49%)
 Frame = +2

Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
           V  + LF + D   +  +L  +  +  +PG+Y+IR+G  G   Y I++GV  VL  G+  
Sbjct: 590 VASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKE 649

Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511
            +    +Y     FGE+ L+    R ASVRA T   L+++    F  +L +    +R
Sbjct: 650 TKLADGSY-----FGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRR 701


>UniRef50_Q4S874 Cluster: Chromosome 5 SCAF14709, whole genome shotgun
            sequence; n=5; Clupeocephala|Rep: Chromosome 5 SCAF14709,
            whole genome shotgun sequence - Tetraodon nigroviridis
            (Green puffer)
          Length = 1512

 Score = 56.8 bits (131), Expect = 3e-07
 Identities = 37/117 (31%), Positives = 59/117 (50%)
 Frame = +2

Query: 161  VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
            V  + LF + D   +  +L  +  +  +PG+Y+IR+G  G   Y I++GV  VL  G+  
Sbjct: 704  VASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGN-- 761

Query: 341  VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511
              K     +GS  FGE+ L+    R ASVRA T   L+++    F  +L +    +R
Sbjct: 762  --KETKLSDGS-YFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRR 815



 Score = 40.7 bits (91), Expect = 0.019
 Identities = 21/71 (29%), Positives = 37/71 (52%)
 Frame = +2

Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
           V  + LF + D   +  +L  +  +  +PG+Y+IR+G  G   Y I++GV  VL  G+  
Sbjct: 562 VASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKE 621

Query: 341 VEKVVHTYEGS 373
            +    +Y G+
Sbjct: 622 TKLSDGSYFGA 632


>UniRef50_Q3W7N0 Cluster: Cyclic nucleotide-binding domain:Peptidase
           M50 precursor; n=1; Frankia sp. EAN1pec|Rep: Cyclic
           nucleotide-binding domain:Peptidase M50 precursor -
           Frankia sp. EAN1pec
          Length = 968

 Score = 56.8 bits (131), Expect = 3e-07
 Identities = 39/137 (28%), Positives = 66/137 (48%), Gaps = 2/137 (1%)
 Frame = +2

Query: 89  DDSDEGAPAVFPKSDAQ-RARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIR 265
           D SD  AP +  +++   RA     + G  LF  L  +    +L  +  +    GE V+ 
Sbjct: 594 DFSDRLAPLLARRAENDTRADERAELEGFALFDGLRTRDKDTLLAHLRARSCVDGEVVVA 653

Query: 266 QGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF-GELALMYNMPRAASVRAQTA 442
           +GD G  FY++ +G   +  T  D   + +    G+G F GE AL+++ P AA+  +   
Sbjct: 654 EGDPGSAFYLVRSGAVALAQTCVDGPPRTL----GAGEFFGESALLHDEPHAATATSVGE 709

Query: 443 GALWAMDRHTFRRILLK 493
             LW +DR TF  ++ +
Sbjct: 710 TRLWELDRTTFDDVVCR 726


>UniRef50_Q0VQV6 Cluster: Cyclic nucleotide-binding domain protein;
           n=1; Alcanivorax borkumensis SK2|Rep: Cyclic
           nucleotide-binding domain protein - Alcanivorax
           borkumensis (strain SK2 / ATCC 700651 / DSM 11573)
          Length = 357

 Score = 56.8 bits (131), Expect = 3e-07
 Identities = 35/111 (31%), Positives = 53/111 (47%), Gaps = 1/111 (0%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT-GDDRVEKV 352
           LF  +    +  +   +   R + GE +IRQG+  D  Y+++ GV +V +  G+     V
Sbjct: 148 LFHRVPPSNILGIFSRLKANRHKEGERIIRQGEAADCCYILKEGVCEVSINIGEGEPTSV 207

Query: 353 VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFK 505
               EG   FGE AL+   PR A+V   T G L  +DR  F  +L +   K
Sbjct: 208 AMLEEGEW-FGEEALLSGKPRNATVSMATDGVLMRLDRQDFDALLREPIIK 257


>UniRef50_UPI0000EC9F34 Cluster: UPI0000EC9F34 related cluster; n=1;
           Gallus gallus|Rep: UPI0000EC9F34 UniRef100 entry -
           Gallus gallus
          Length = 747

 Score = 56.4 bits (130), Expect = 4e-07
 Identities = 36/117 (30%), Positives = 60/117 (51%)
 Frame = +2

Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
           V  + LF + D   +  +L  +  +  +PG+Y+IR+G  G   Y I++GV  +L  G+  
Sbjct: 392 VASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSILTKGN-- 449

Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511
             K +   +GS  FGE+ L+    R ASVRA T   L+++    F  +L +    +R
Sbjct: 450 --KEMKLSDGS-YFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRR 503


>UniRef50_Q6WL05 Cluster: Hyperpolarization-activated ion channel;
           n=10; Pancrustacea|Rep: Hyperpolarization-activated ion
           channel - Panulirus argus (Spiny lobster)
          Length = 691

 Score = 56.4 bits (130), Expect = 4e-07
 Identities = 33/110 (30%), Positives = 60/110 (54%), Gaps = 1/110 (0%)
 Frame = +2

Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
           V  +  F + DA+ +  V+  +  +  +PG+ +I++G  G+  Y I+ G+ D++++  + 
Sbjct: 429 VASVPFFANADARFVTDVVTKLRYEVYQPGDIIIKEGTIGNKMYFIQEGIVDIVMSNGE- 487

Query: 341 VEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
               V T    GS FGE+ L+ N  R ASVRA+T   L+++    F  +L
Sbjct: 488 ----VATSLSDGSYFGEICLLTNARRTASVRAETYCNLFSLSVEHFNTVL 533


>UniRef50_A5G0B9 Cluster: Putative transcriptional regulator,
           Crp/Fnr family; n=1; Acidiphilium cryptum JF-5|Rep:
           Putative transcriptional regulator, Crp/Fnr family -
           Acidiphilium cryptum (strain JF-5)
          Length = 227

 Score = 56.0 bits (129), Expect = 5e-07
 Identities = 31/106 (29%), Positives = 55/106 (51%)
 Frame = +2

Query: 170 ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEK 349
           I LF     +++  +    +E+    GE +I++GD G +  +I  G   V++ G D  ++
Sbjct: 12  IPLFAPFSPEELDALYACTYERNMTTGEMLIQRGDPGTSMMLILAGEVRVVLPGIDGNDQ 71

Query: 350 VVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
            ++T      FGE+AL    PR+A V A T G L  ++R +  R++
Sbjct: 72  DLNTLREGAVFGEIALFDGKPRSADVVAATNGRLLVLERASVVRLI 117


>UniRef50_A0LNC0 Cluster: Cyclic nucleotide-binding protein; n=1;
           Syntrophobacter fumaroxidans MPOB|Rep: Cyclic
           nucleotide-binding protein - Syntrophobacter
           fumaroxidans (strain DSM 10017 / MPOB)
          Length = 171

 Score = 56.0 bits (129), Expect = 5e-07
 Identities = 35/138 (25%), Positives = 73/138 (52%)
 Frame = +2

Query: 80  PEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYV 259
           P E +S E APA   + + + +   E +R + +F  +   +++       +   + GE++
Sbjct: 4   PTERNS-ECAPASRGRCELEDS--LEILRNVSVFAGIPLPRLKLYAYLSRKMCFQAGEFL 60

Query: 260 IRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 439
             QGD GD  Y++ +G   V+    +    ++H ++    FG +AL+ ++ R  SVRA T
Sbjct: 61  FHQGDSGDRGYIVISGRLQVIRELKEH-SVLLHEFKPGDFFGGMALLSDVNRLFSVRAVT 119

Query: 440 AGALWAMDRHTFRRILLK 493
           +    ++DR +FR+++++
Sbjct: 120 SAECLSLDRESFRKLMIQ 137


>UniRef50_Q23EB7 Cluster: Cyclic nucleotide-binding domain
           containing protein; n=1; Tetrahymena thermophila
           SB210|Rep: Cyclic nucleotide-binding domain containing
           protein - Tetrahymena thermophila SB210
          Length = 1079

 Score = 56.0 bits (129), Expect = 5e-07
 Identities = 28/114 (24%), Positives = 60/114 (52%), Gaps = 2/114 (1%)
 Frame = +2

Query: 152 AEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTG 331
           ++ ++   +F+    Q + +++  M E    PGE +  +GD  D+ Y+I NG  ++ ++G
Sbjct: 504 SQIIKKFDIFKCFSQQTINKLVFLMKEIIVSPGETIFLEGDLDDSVYLILNGQIEIFISG 563

Query: 332 --DDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
             ++   K++     +  FGE+A     PR+AS ++     L+ ++R  F +I+
Sbjct: 564 NQNNSQTKILKDLSNNQIFGEIAFFCQKPRSASAKSIVLSTLYKIERKDFMQII 617


>UniRef50_Q2LV90 Cluster: CAMP-dependent transcriptional regulator;
           n=2; Syntrophus aciditrophicus SB|Rep: CAMP-dependent
           transcriptional regulator - Syntrophus aciditrophicus
           (strain SB)
          Length = 249

 Score = 55.6 bits (128), Expect = 6e-07
 Identities = 29/114 (25%), Positives = 55/114 (48%)
 Frame = +2

Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
           + ++ I LF S +  +++ +   +  +  + GE +  +GD G  F++I NG+  + V+  
Sbjct: 28  DLLKAIPLFESFNNSELRHLASLLKGQSLDKGEILFHKGDTGSAFFIIANGLIRISVSNK 87

Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKS 496
              E       G   FGE+AL+    R+A   A     L+ +DR+ F   L ++
Sbjct: 88  AGDEVTFAHLRGGDFFGEMALLDEQTRSADATALEDSTLYVLDRNDFFPFLFEN 141


>UniRef50_Q0F2T2 Cluster: Glucose-6-phosphate 1-dehydrogenase; n=1;
           Mariprofundus ferrooxydans PV-1|Rep: Glucose-6-phosphate
           1-dehydrogenase - Mariprofundus ferrooxydans PV-1
          Length = 665

 Score = 55.6 bits (128), Expect = 6e-07
 Identities = 32/81 (39%), Positives = 45/81 (55%)
 Frame = +2

Query: 248 GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASV 427
           G+ + R G +G   Y+IE G  DV+    D    VV T  G   FGEL+L+    R ASV
Sbjct: 558 GDEIARLGTEGRELYIIEMGSVDVI----DPEGNVVTTLSGGQVFGELSLLVTKERRASV 613

Query: 428 RAQTAGALWAMDRHTFRRILL 490
           RA T  AL+ M++  F ++L+
Sbjct: 614 RAVTYCALYMMEKRDFCKVLM 634


>UniRef50_Q08V69 Cluster: PKA regulatory subunit-like protein; n=1;
           Stigmatella aurantiaca DW4/3-1|Rep: PKA regulatory
           subunit-like protein - Stigmatella aurantiaca DW4/3-1
          Length = 450

 Score = 55.6 bits (128), Expect = 6e-07
 Identities = 34/105 (32%), Positives = 51/105 (48%)
 Frame = +2

Query: 170 ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEK 349
           I LF SL  +   ++L  +     + GE ++++G  G + +VI  G  +V+  G +    
Sbjct: 177 IPLFASLGREMFLEMLAGVERSVFQRGERILQEGAPGSSMFVIVEGEVNVVRQGQEGQPL 236

Query: 350 VVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484
            V T    G FGE+AL+Y +PR ASV A T   L    R     I
Sbjct: 237 TVATLGEGGFFGEMALLYPVPRLASVVAGTRTVLLEFSRERMEDI 281



 Score = 33.9 bits (74), Expect = 2.2
 Identities = 28/114 (24%), Positives = 45/114 (39%)
 Frame = +2

Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 328
           LA  +R  LLF +      + V +A        GE ++ +G      Y +  G   V   
Sbjct: 301 LANVLRSNLLFAAWPEALQRGVAEAFTPVAVPAGEELLTRGHPAHQLYFLLRGHCTVFHK 360

Query: 329 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILL 490
             D  E           FGE++L+ +    ASVR  T   L  +++    R+L+
Sbjct: 361 HLDGHETAYPGMNEGAVFGEVSLLRSRLVTASVRTTTPCVLLKLEQTHLERLLM 414


>UniRef50_A7BXC8 Cluster: MscS Mechanosensitive ion channel; n=1;
           Beggiatoa sp. PS|Rep: MscS Mechanosensitive ion channel
           - Beggiatoa sp. PS
          Length = 564

 Score = 55.6 bits (128), Expect = 6e-07
 Identities = 29/84 (34%), Positives = 45/84 (53%)
 Frame = +2

Query: 236 RSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPR 415
           R  PG+ +++QGD GD+ ++I  GV  VLV  DD   K V        FGE+AL+    R
Sbjct: 424 RFNPGDTIVQQGDAGDSLFIIVEGVVSVLVQTDDGRTKEVARLGAGNFFGEMALLTGEER 483

Query: 416 AASVRAQTAGALWAMDRHTFRRIL 487
            A+V+A     L+ + +   R ++
Sbjct: 484 MATVKALVDTYLFELTKADIRPLI 507


>UniRef50_Q2RX44 Cluster: Cyclic nucleotide-binding domain (CNMP-BD)
           protein; n=1; Rhodospirillum rubrum ATCC 11170|Rep:
           Cyclic nucleotide-binding domain (CNMP-BD) protein -
           Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255)
          Length = 129

 Score = 55.2 bits (127), Expect = 8e-07
 Identities = 31/84 (36%), Positives = 43/84 (51%)
 Frame = +2

Query: 248 GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASV 427
           G  V R+GD  D  Y++E+G+ D++V   D  E V+ T      FGE+AL+   PR A+ 
Sbjct: 20  GAVVFREGDAADGVYLVESGLVDMIVRRPDGSEAVIGTVGAGEVFGEMALIDGHPRMATA 79

Query: 428 RAQTAGALWAMDRHTFRRILLKSA 499
           R      L  +    F R  LKSA
Sbjct: 80  RVAMEATLVRVSNEAF-RAQLKSA 102


>UniRef50_Q695H0 Cluster: CGMP-dependent protein kinase; n=1;
           Chlamydomonas reinhardtii|Rep: CGMP-dependent protein
           kinase - Chlamydomonas reinhardtii
          Length = 1027

 Score = 55.2 bits (127), Expect = 8e-07
 Identities = 37/132 (28%), Positives = 67/132 (50%), Gaps = 15/132 (11%)
 Frame = +2

Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQG---DDGDNFYVIENGVFDV 319
           + EA++   +F+ +    + +V+  M+    + G  V++QG      D  Y ++ G  +V
Sbjct: 157 ILEALKRNFVFKGIPQNHLVEVVGRMYGISFKSGAVVLQQGALPKQDDCMYYLQQGEAEV 216

Query: 320 LVTGDDRVEK-----------VVHTYEGSG-SFGELALMYNMPRAASVRAQTAGALWAMD 463
           +++G     K            V   +  G  FG++AL+++ PR ASV A+T   +WAMD
Sbjct: 217 VISGGADASKNHGEERKVDGHTVRIPQKPGWLFGDVALLFHSPRTASVVAKTNITVWAMD 276

Query: 464 RHTFRRILLKSA 499
           R TF + ++K A
Sbjct: 277 RRTFLKFVMKHA 288



 Score = 46.4 bits (105), Expect = 4e-04
 Identities = 29/87 (33%), Positives = 46/87 (52%), Gaps = 4/87 (4%)
 Frame = +2

Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSE--PGEYVIRQGDDGDNFYVIENGVFDVL 322
           ++  +R +  F+ L  +QM+ +LD  F+ R E   G+ ++ QGD  +  YV++ G    L
Sbjct: 418 VSAVIRSLPQFKGLKQEQMENILD-RFDAREELMQGDTILNQGDMLEKLYVVKIGEI-AL 475

Query: 323 VTGDDRVE--KVVHTYEGSGSFGELAL 397
              D+RVE    VH   G   FGE A+
Sbjct: 476 FRNDERVEDPNFVHEIAGFSYFGETAI 502


>UniRef50_UPI0000383B9A Cluster: COG0642: Signal transduction
           histidine kinase; n=1; Magnetospirillum magnetotacticum
           MS-1|Rep: COG0642: Signal transduction histidine kinase
           - Magnetospirillum magnetotacticum MS-1
          Length = 385

 Score = 54.8 bits (126), Expect = 1e-06
 Identities = 29/105 (27%), Positives = 54/105 (51%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
           LF   D + +++++    E     GE + R+GD GD+ YV+ +G  ++ V        V+
Sbjct: 16  LFTVQDEETLKRIIACGSEVLLSDGECLFRKGDMGDSIYVVLDGAIEISVQDGGGEFHVM 75

Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILL 490
           +  E    FGE+A++ N+PR A+  A+    L  +    F +I++
Sbjct: 76  NVLEVGSLFGEVAILDNLPRTANAAARGGAHLLRITGGDFHQIMI 120


>UniRef50_Q4RR21 Cluster: Chromosome 14 SCAF15003, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 14
           SCAF15003, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 621

 Score = 54.8 bits (126), Expect = 1e-06
 Identities = 27/80 (33%), Positives = 43/80 (53%)
 Frame = +2

Query: 188 LDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYE 367
           LD +Q   ++D +     +PG +VI++G +GD+ Y++  G   V   G D     + T  
Sbjct: 16  LDDEQTAMMVDLLAVSNFKPGSHVIKEGSEGDSMYIVAGGQLQVTQAGRD-----LRTLT 70

Query: 368 GSGSFGELALMYNMPRAASV 427
               FGELA++YN  R A+V
Sbjct: 71  TGDVFGELAILYNCKRTATV 90



 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 30/122 (24%), Positives = 62/122 (50%), Gaps = 1/122 (0%)
 Frame = +2

Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 304
           KS  +R +L   ++     + L+  Q+ +++D+M E + +  + ++R+G + + FY+I  
Sbjct: 147 KSKKRREQLMGFLKMSQTLKDLNNVQLSKIIDSMEEVKYQDKDVIVREGAEANTFYIILK 206

Query: 305 GVFDVLVTGD-DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481
           G  +VLVT + +  +K +        FGE AL+  + R A+  A      + +D+  F  
Sbjct: 207 G--EVLVTKNVNGHQKQIRRMGKGEHFGEQALIREVLRTATCTADGPVTCFTIDKEVFEE 264

Query: 482 IL 487
            +
Sbjct: 265 TI 266


>UniRef50_Q2S6T5 Cluster: CAMP-binding protein-catabolite gene
           activator and regulatory subunit of cAMP-dependent
           protein kinase; n=1; Hahella chejuensis KCTC 2396|Rep:
           CAMP-binding protein-catabolite gene activator and
           regulatory subunit of cAMP-dependent protein kinase -
           Hahella chejuensis (strain KCTC 2396)
          Length = 360

 Score = 54.8 bits (126), Expect = 1e-06
 Identities = 34/105 (32%), Positives = 62/105 (59%), Gaps = 1/105 (0%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEK-RSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKV 352
           LF +L    +++V  A FE+   + G+ +I +GD+GD FY++ +G   V++ GD+   K 
Sbjct: 167 LFFNLPPANVEKVF-ARFERIEVKKGQVIIEEGDEGDYFYLLIDGSARVVIGGDE--SKP 223

Query: 353 VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
           +   +GS  FGE AL+ +  R+A++     G L  +D+ +F+ +L
Sbjct: 224 IRVSKGS-YFGEEALVSDTVRSATIIMSEDGVLARLDKKSFQSLL 267


>UniRef50_A0DBC7 Cluster: Chromosome undetermined scaffold_44, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_44,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 495

 Score = 54.8 bits (126), Expect = 1e-06
 Identities = 37/123 (30%), Positives = 58/123 (47%), Gaps = 6/123 (4%)
 Frame = +2

Query: 137 QRARLAEAVRGILLFRSLDAQQMQ---QVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG 307
           Q  +L E +  I  F  L   + Q    + DA+  K     E + +QGD GD FY++  G
Sbjct: 38  QAIKLQELLSTIKYFAQLFQSKQQLIYDIADALQYKFVHQNEIIFKQGDQGDMFYIVLQG 97

Query: 308 VFDVLVT---GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFR 478
              + +     D  V K V T    GSFGELAL  +  R A+  + T      +D+ T++
Sbjct: 98  TVSIQINIPQEDVFVPKEVATITEGGSFGELALQSSQARTATSISVTDCHFATIDKTTYK 157

Query: 479 RIL 487
           +++
Sbjct: 158 QLI 160


>UniRef50_Q09BB2 Cluster: Cyclic nucleotide-binding:Bacterial
           regulatory protein, Crp; n=2; Stigmatella aurantiaca
           DW4/3-1|Rep: Cyclic nucleotide-binding:Bacterial
           regulatory protein, Crp - Stigmatella aurantiaca DW4/3-1
          Length = 226

 Score = 54.4 bits (125), Expect = 1e-06
 Identities = 31/107 (28%), Positives = 55/107 (51%), Gaps = 1/107 (0%)
 Frame = +2

Query: 170 ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEK 349
           I LF +L A+ ++ +   +  +    G+ + +QGD+G + Y++  G   + +   +  E 
Sbjct: 10  IPLFENLQAEDLEHLSTLLHTRHCAKGDVIFQQGDEGADLYIVRAGQVAIRLHSPEGKE- 68

Query: 350 VVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
           V+ T  GSG  FGEL+L+   PR+    A+    L ++ R  F R L
Sbjct: 69  VILTLLGSGEVFGELSLLDGEPRSTHAVAREETVLLSLRREDFHRFL 115


>UniRef50_A0YAY7 Cluster: CAMP-binding protein-catabolite gene
           activator and regulatory subunit of cAMP-dependent
           protein kinase; n=1; marine gamma proteobacterium
           HTCC2143|Rep: CAMP-binding protein-catabolite gene
           activator and regulatory subunit of cAMP-dependent
           protein kinase - marine gamma proteobacterium HTCC2143
          Length = 361

 Score = 54.4 bits (125), Expect = 1e-06
 Identities = 34/109 (31%), Positives = 57/109 (52%), Gaps = 1/109 (0%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVE-KV 352
           LF  +    ++++LD      +  G+ ++RQG+ GD  Y I+ GV  V    +++    +
Sbjct: 154 LFYKVPPMNIRKILDKFSAHYASAGDTILRQGELGDCCYYIKEGVAGVYQAENEKSSPSL 213

Query: 353 VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSA 499
           V   +    FGE AL+ + PR A++   T G L  +D+  F  +LLKSA
Sbjct: 214 VAELDVGRCFGEDALVNDAPRNATITMHTNGVLMRLDKRDF-FLLLKSA 261


>UniRef50_A0GWU5 Cluster: Stage II sporulation E; n=2;
           Chloroflexus|Rep: Stage II sporulation E - Chloroflexus
           aggregans DSM 9485
          Length = 563

 Score = 54.4 bits (125), Expect = 1e-06
 Identities = 30/113 (26%), Positives = 58/113 (51%)
 Frame = +2

Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 328
           + + +R + LF+++    +  +   + E R  PGE +  QGD G   YV+ +G  +V +T
Sbjct: 139 MLDRLRSLPLFQAVPEAVLSALAPRLAECRLAPGEVLFHQGDTGHECYVVLSGAVEV-IT 197

Query: 329 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
             +  E  +  +      GE++L+ + PR+A+VRA     L A++   F  ++
Sbjct: 198 FVNGAELRLEVFHSGQIIGEMSLIDHSPRSATVRAIEPSRLVALNEQVFATLI 250


>UniRef50_Q3MD80 Cluster: Cyclic nucleotide-binding domain (CNMP-BD)
           protein; n=1; Anabaena variabilis ATCC 29413|Rep: Cyclic
           nucleotide-binding domain (CNMP-BD) protein - Anabaena
           variabilis (strain ATCC 29413 / PCC 7937)
          Length = 408

 Score = 54.0 bits (124), Expect = 2e-06
 Identities = 28/83 (33%), Positives = 45/83 (54%)
 Frame = +2

Query: 185 SLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTY 364
           +L  +Q+ Q+L  +     +PGE VI QGD  D FY++  G  +V+    D   K++   
Sbjct: 236 TLTDKQLIQLLPQLKMLTFQPGEIVIHQGDLADKFYILMEGEVEVIQEDGDSEPKLLKRL 295

Query: 365 EGSGSFGELALMYNMPRAASVRA 433
             +  FGE+ L++   R A+VRA
Sbjct: 296 GPNSYFGEIGLLHETTRTATVRA 318


>UniRef50_Q5WUW4 Cluster: Putative uncharacterized protein; n=4;
           Legionella pneumophila|Rep: Putative uncharacterized
           protein - Legionella pneumophila (strain Lens)
          Length = 153

 Score = 53.6 bits (123), Expect = 3e-06
 Identities = 27/107 (25%), Positives = 54/107 (50%), Gaps = 5/107 (4%)
 Frame = +2

Query: 173 LLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV-----TGDD 337
           +LF+ +D + + + L+   E     GE++  Q + GD+ Y++E G   +++       D 
Sbjct: 10  MLFKGVDGKYIDEFLENCEEVELPQGEFLFHQNEIGDSMYIVEQGELQIILEQNSTDSDT 69

Query: 338 RVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFR 478
           + E+++  ++     GEL +   + RAAS+RA     L  ++   FR
Sbjct: 70  KEEQLIGVFKSGSLVGELCVFGQLKRAASIRALADCRLLKIEGEDFR 116


>UniRef50_P74736 Cluster: CAMP protein kinase regulatory chain; n=2;
           Chroococcales|Rep: CAMP protein kinase regulatory chain
           - Synechocystis sp. (strain PCC 6803)
          Length = 434

 Score = 53.6 bits (123), Expect = 3e-06
 Identities = 34/107 (31%), Positives = 53/107 (49%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
           +  +L  Q+  Q+   +    + P E + R+GD GD FY I  G  DV   G   V ++ 
Sbjct: 139 VMNALPEQERHQLAGLLTPHHAYPREVLCREGDQGDYFYFIGGGEADV-YKGTTWVNRLT 197

Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKS 496
                   FGE++L+   PR+A+V A T   L+ +D+  F  IL +S
Sbjct: 198 ----SGDIFGEMSLLTGEPRSATVVAVTPMELYQLDKENFANILSQS 240


>UniRef50_A5UY70 Cluster: Cyclic nucleotide-binding protein; n=3;
           Chloroflexaceae|Rep: Cyclic nucleotide-binding protein -
           Roseiflexus sp. RS-1
          Length = 388

 Score = 53.6 bits (123), Expect = 3e-06
 Identities = 30/86 (34%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
 Frame = +2

Query: 245 PGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAAS 424
           PG  +I QG   DNFY+I  G  +V +   D  E +V+       FGE+ L++   R A 
Sbjct: 277 PGAVIIEQGSPADNFYIITRGDVEVFIEHPDGGEIIVNHLSTGSYFGEIGLLHQGRRTAG 336

Query: 425 VRAQTAGALWA--MDRHTFRRILLKS 496
           VRA  A    A  +D+  F  +L +S
Sbjct: 337 VRASFATGCDAAVLDQQEFHTLLAES 362


>UniRef50_A5PH37 Cluster: AKT2 inward rectifier channel; n=6;
           Embryophyta|Rep: AKT2 inward rectifier channel -
           Physcomitrella patens (Moss)
          Length = 967

 Score = 53.6 bits (123), Expect = 3e-06
 Identities = 35/132 (26%), Positives = 60/132 (45%), Gaps = 3/132 (2%)
 Frame = +2

Query: 101 EGAPAVFPK---SDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQG 271
           +G  AV PK   S   +    E V  + LF       + Q++  M  +   P E +I   
Sbjct: 361 QGTMAVLPKAIRSSIAQYLFLETVEKVYLFHGTSYNFLTQLVTEMKAEYFPPREEIILFN 420

Query: 272 DDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGAL 451
           +    FY++ NG  DV +T  D  E+++ T       GE+ ++  MP+  +VR++    L
Sbjct: 421 EAPSEFYIVVNGSVDV-ITMKDASEQILFTAVTGDVIGEIGVLCYMPQPFTVRSRKLSQL 479

Query: 452 WAMDRHTFRRIL 487
             +DR  F  ++
Sbjct: 480 LRLDRSVFMNVV 491


>UniRef50_O76977 Cluster: Hyperpolarization-activated (Ih) channel;
           n=5; Eumetazoa|Rep: Hyperpolarization-activated (Ih)
           channel - Strongylocentrotus purpuratus (Purple sea
           urchin)
          Length = 767

 Score = 53.6 bits (123), Expect = 3e-06
 Identities = 31/122 (25%), Positives = 62/122 (50%), Gaps = 1/122 (0%)
 Frame = +2

Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 304
           + D       + V  +  F   D+  + +V+  +  +  +P +YVI++G  GD  + I+ 
Sbjct: 528 RQDVANYNCRDLVASVPFFVGADSNFVTRVVTLLEFEVFQPADYVIQEGTFGDRMFFIQQ 587

Query: 305 GVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481
           G+ D++++     + V+ T    GS FGE+ L+    R ASV+ +T   L+++    F +
Sbjct: 588 GIVDIIMS-----DGVIATSLSDGSYFGEICLLTRERRVASVKCETYCTLFSLSVQHFNQ 642

Query: 482 IL 487
           +L
Sbjct: 643 VL 644


>UniRef50_A0DKC6 Cluster: Chromosome undetermined scaffold_54, whole
           genome shotgun sequence; n=3; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_54,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 503

 Score = 53.6 bits (123), Expect = 3e-06
 Identities = 35/97 (36%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
 Frame = +2

Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT--GDDRVEKVVHTYEGSGSFGELAL 397
           MF ++ +  E V      G  FYVI +G  +VL+   G D +E V    +G  SFGELAL
Sbjct: 58  MFIEKFQSTEVVFHLDTIGTKFYVILDGQVEVLIRRRGFDELESVRILKKGE-SFGELAL 116

Query: 398 MYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKK 508
           ++  PR A++R  T      +D+  F++IL     KK
Sbjct: 117 IHKQPRLATIRCVTDCTFAILDKQQFQKILHYEQTKK 153



 Score = 32.7 bits (71), Expect = 5.1
 Identities = 13/50 (26%), Positives = 27/50 (54%)
 Frame = +2

Query: 170 ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDV 319
           I +F  L+  Q+  +    F    E  + V+++G+  D+F +++ G+F V
Sbjct: 164 ISIFNQLNRTQLTSIYLNSFLYEYEKNQVVVQEGEKSDSFLIVKQGLFQV 213


>UniRef50_A1Z9N7 Cluster: CG8585-PE, isoform E; n=18;
            Pancrustacea|Rep: CG8585-PE, isoform E - Drosophila
            melanogaster (Fruit fly)
          Length = 1327

 Score = 53.2 bits (122), Expect = 3e-06
 Identities = 33/110 (30%), Positives = 57/110 (51%), Gaps = 1/110 (0%)
 Frame = +2

Query: 161  VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
            V  +  F + D+  +  V+  +  +  +PG+ +I++G  G   Y I+ GV D+++   + 
Sbjct: 1119 VASVPFFANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGE- 1177

Query: 341  VEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
                V T    GS FGE+ L+ N  R ASVRA+T   L+++    F  +L
Sbjct: 1178 ----VATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNCVL 1223


>UniRef50_UPI000038CAE8 Cluster: COG1252: NADH dehydrogenase,
           FAD-containing subunit; n=1; Nostoc punctiforme PCC
           73102|Rep: COG1252: NADH dehydrogenase, FAD-containing
           subunit - Nostoc punctiforme PCC 73102
          Length = 980

 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 31/94 (32%), Positives = 51/94 (54%)
 Frame = +2

Query: 185 SLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTY 364
           S+  Q+ Q +  A F+     G+ +++QGD G   Y+I NG  +VL    +  E ++ T 
Sbjct: 421 SMKVQEKQSLKKAYFQA----GQVIVKQGDIGRCLYLIRNGEVEVLQEMSNG-ETIIQTI 475

Query: 365 EGSGSFGELALMYNMPRAASVRAQTAGALWAMDR 466
                FGE +++ N P  A+VRA+T+  L  +DR
Sbjct: 476 GSGEHFGETSVIENSPHIATVRAKTSVQLVVIDR 509


>UniRef50_A0DG99 Cluster: Chromosome undetermined scaffold_5, whole
           genome shotgun sequence; n=4; Oligohymenophorea|Rep:
           Chromosome undetermined scaffold_5, whole genome shotgun
           sequence - Paramecium tetraurelia
          Length = 869

 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 33/111 (29%), Positives = 59/111 (53%), Gaps = 1/111 (0%)
 Frame = +2

Query: 146 RLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV 325
           R  + +  I +F  L  + ++ +LD++  +   PG+ VI++G  GD FY+IE+G+    V
Sbjct: 606 RRLDLLSTIDIFEHLTLKNVRWLLDSVTSEEFFPGQDVIKEGTAGDRFYIIESGL--ARV 663

Query: 326 TGDDRVEKVVHTYEGSGSFGELALMYNM-PRAASVRAQTAGALWAMDRHTF 475
               + ++    Y+    FGE A++ N   R ASV A T   +  +++H F
Sbjct: 664 YSKQKGQEFERYYQVGDYFGESAVLSNEGRRGASVEAVTNLKVLILEKHDF 714


>UniRef50_Q3AAI0 Cluster: CBS/cyclic nucleotide-binding domain
           protein; n=1; Carboxydothermus hydrogenoformans
           Z-2901|Rep: CBS/cyclic nucleotide-binding domain protein
           - Carboxydothermus hydrogenoformans (strain Z-2901 / DSM
           6008)
          Length = 631

 Score = 52.4 bits (120), Expect = 6e-06
 Identities = 27/117 (23%), Positives = 58/117 (49%), Gaps = 1/117 (0%)
 Frame = +2

Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDN-FYVIENGVFDVLV 325
           + + +  I  F  L    ++++ +++  +  +PGEY+ R+ +   N  +++ NG+ +++V
Sbjct: 1   MPQTLSHIYPFSLLPENLLEELSNSLTSRNYQPGEYIFREKEPARNGLFLVFNGILEIVV 60

Query: 326 TGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKS 496
           T +   + V+        FGE  L    P  A +RA T   +  + ++ F  IL K+
Sbjct: 61  TSERGQDLVIALRRPGEFFGETVLFSGEPYPAGIRAATEALIGFIPKNIFMEILNKN 117


>UniRef50_A7SE96 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 174

 Score = 52.4 bits (120), Expect = 6e-06
 Identities = 38/110 (34%), Positives = 56/110 (50%), Gaps = 6/110 (5%)
 Frame = +2

Query: 179 FRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG------VFDVLVTGDDR 340
           F     +  QQ +   + +  E    +IRQG   +NFY I +G      +F   VTG+ R
Sbjct: 51  FGEYPLKMQQQPVKVGWYESFEAKRVIIRQGHPAENFYFILSGTALVTLLFVDPVTGEQR 110

Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILL 490
              V    +GS SFGELAL+++  R+A+V  +   AL A+ R  FR I +
Sbjct: 111 SNTVAVLGKGS-SFGELALLHHKTRSATVLCKEDVALLAVGREDFRDIFM 159


>UniRef50_A0DXZ3 Cluster: Chromosome undetermined scaffold_69, whole
           genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_69,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 945

 Score = 52.4 bits (120), Expect = 6e-06
 Identities = 44/123 (35%), Positives = 62/123 (50%), Gaps = 10/123 (8%)
 Frame = +2

Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFE---KRSEPGEYVIRQGDDGDNFYVI---ENGV 310
           L + V  I  F++L +Q    VL  M     K  +  E +   GD G  FY+I     GV
Sbjct: 458 LLQLVEAIAFFKNLQSQNPDIVLRCMSVLSYKTVKKEEILFHVGDQGSLFYIILKGSVGV 517

Query: 311 FDVLVTGDD--RVE-KVVHTYEGSGSFGELALMY-NMPRAASVRAQTAGALWAMDRHTFR 478
           F +L + DD  R E K V+  +   SFGELAL+  N  R A++ A+    L  M++H F+
Sbjct: 518 FILLPSPDDSKRFELKEVNILKAGNSFGELALLNDNAKRTATIIAKEDCMLAIMEKHHFK 577

Query: 479 RIL 487
            IL
Sbjct: 578 SIL 580


>UniRef50_P74608 Cluster: Slr1575 protein; n=1; Synechocystis sp.
           PCC 6803|Rep: Slr1575 protein - Synechocystis sp.
           (strain PCC 6803)
          Length = 479

 Score = 52.0 bits (119), Expect = 8e-06
 Identities = 29/113 (25%), Positives = 62/113 (54%)
 Frame = +2

Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 328
           L++ ++    F  L+  +++Q+++    +  +  E + R+ D  D FY++ +G+ +V   
Sbjct: 314 LSQVLKSSDYFSGLNELEIRQLVEIGQLQSLQSEEVLFRERDPADGFYIVISGLVEVYT- 372

Query: 329 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
             +++ +V+ +      FGELALM  +PR ASV+A+    L+ +    F ++L
Sbjct: 373 --EKLGRVLASLGPGSFFGELALMLGIPRTASVKAKEKSLLFVVRFPQFEQLL 423


>UniRef50_Q2ADG0 Cluster: Cyclic nucleotide-binding:Bacterial
           regulatory protein, Crp; n=1; Halothermothrix orenii H
           168|Rep: Cyclic nucleotide-binding:Bacterial regulatory
           protein, Crp - Halothermothrix orenii H 168
          Length = 219

 Score = 52.0 bits (119), Expect = 8e-06
 Identities = 28/113 (24%), Positives = 54/113 (47%)
 Frame = +2

Query: 164 RGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRV 343
           R I LF  L+ +Q+  +     ++R + GE +  +GD  D FY++  G   ++    D  
Sbjct: 7   RSIPLFSGLNDEQLDLLKSITNKRRYKAGEILFFEGDKPDAFYIVVEGEIQIIKVSYDGK 66

Query: 344 EKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAF 502
           EK++        FGE+A++ +  R+A+ R     +L  +    F  ++ +  F
Sbjct: 67  EKILEVMGPGDFFGEMAIIDSKGRSATARVIRDSSLLVVGNQEFLNLVREYPF 119


>UniRef50_Q7UTR3 Cluster: ATP-binding subunit of ABC transporter;
           n=1; Pirellula sp.|Rep: ATP-binding subunit of ABC
           transporter - Rhodopirellula baltica
          Length = 397

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 3/120 (2%)
 Frame = +2

Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316
           + A L E +    +F  +    + ++  +M      PG+ ++  GD GD FY+I  G   
Sbjct: 262 EAAVLGEMLSQCSVFSGVAISTLTELSRSMTRTTHGPGDRIVTYGDVGDRFYLIREGTVS 321

Query: 317 V---LVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
           V      G +   +V    EG+  FGE AL+   PR A V A T    +++D  TF  ++
Sbjct: 322 VKQPTQPGGNDFREVAQLGEGA-YFGETALLTGEPRNAHVDATTETVTYSLDAPTFSDVM 380


>UniRef50_Q46TY3 Cluster: Cyclic nucleotide-binding; n=2;
           Cupriavidus necator|Rep: Cyclic nucleotide-binding -
           Ralstonia eutropha (strain JMP134) (Alcaligenes
           eutrophus)
          Length = 260

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 35/130 (26%), Positives = 52/130 (40%), Gaps = 2/130 (1%)
 Frame = +2

Query: 104 GAPAVFPKSDA--QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDD 277
           G P   P  +A   RA  A  ++    F  L     + +LD    +    GE +  +GD 
Sbjct: 16  GIPRGTPGGNAAPSRAEAAATLQASAWFSQLPGPLREALLDDGTWRHLAAGEALFARGDA 75

Query: 278 GDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWA 457
            D  Y + +G   V   G+     ++   E    FGE+ L   +PR    RA  A  LW 
Sbjct: 76  FDGLYCVASGTMQVDAAGESGKAALLGLLEAGAWFGEICLFDGLPRTHDARAVHAARLWH 135

Query: 458 MDRHTFRRIL 487
           + R +  R L
Sbjct: 136 VPRASLERRL 145


>UniRef50_Q1D9I5 Cluster: PBS lyase HEAT-like repeat/cyclic
            nucleotide-binding domain protein; n=2;
            Cystobacterineae|Rep: PBS lyase HEAT-like repeat/cyclic
            nucleotide-binding domain protein - Myxococcus xanthus
            (strain DK 1622)
          Length = 1034

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 31/110 (28%), Positives = 49/110 (44%)
 Frame = +2

Query: 158  AVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDD 337
            A+ G+ +F   D   +  +     E     GE +  QGD GD  YVI +G  D    G+ 
Sbjct: 866  ALEGVSVFSQCDVDDIAAIAAVAREASFRTGERIYAQGDPGDALYVIVDGAVDAFHDGEH 925

Query: 338  RVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
                 V  ++G  +FGE++L+   PR   + A     +  +DR  F  +L
Sbjct: 926  -----VLRFQGKQAFGEVSLLDGAPRPTDMVAAVDTRVLIIDRRDFLDLL 970


>UniRef50_Q8ILS1 Cluster: Putative uncharacterized protein; n=1;
           Plasmodium falciparum 3D7|Rep: Putative uncharacterized
           protein - Plasmodium falciparum (isolate 3D7)
          Length = 838

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 31/110 (28%), Positives = 55/110 (50%), Gaps = 1/110 (0%)
 Frame = +2

Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
           +R + + R L  +++ Q+  AM  +   P   +I+     D FY+I  G+  V    +  
Sbjct: 591 LRNVPILRYLSEEELVQISYAMKLEMYHPNHTIIKANTYDDKFYIICKGLVTVEKNTEGN 650

Query: 341 VEKVV-HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
            +K+V    + +  FGELAL+ N+ R A+V   T   L ++    F+R+L
Sbjct: 651 KDKIVLSNLKKTDYFGELALIKNIKRTANVILDTEAILLSLSDSEFKRLL 700


>UniRef50_Q7RDH4 Cluster: Reticulocyte-binding protein 2 homolog A,
            putative; n=7; Plasmodium (Vinckeia)|Rep:
            Reticulocyte-binding protein 2 homolog A, putative -
            Plasmodium yoelii yoelii
          Length = 1939

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 29/114 (25%), Positives = 58/114 (50%), Gaps = 1/114 (0%)
 Frame = +2

Query: 149  LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 328
            + + ++ + + R L  + +  +  +M  +  EP   +I++GD  D FY+I  G+  V + 
Sbjct: 1737 ILQVLKNVPILRYLPLEILDNISYSMKIEIHEPNHTIIKEGDYDDKFYIICKGLATVDIP 1796

Query: 329  GDDRVEK-VVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
                  K ++ + + +  FGEL+L+ N  R A+V   T   L+++    F R+L
Sbjct: 1797 SKFSYNKLIISSLKKADYFGELSLINNTARTANVVLDTTSILFSLVSSEFNRLL 1850



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 23/87 (26%), Positives = 49/87 (56%), Gaps = 1/87 (1%)
 Frame = +2

Query: 251 EYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVR 430
           +++IRQ DD  +FY++++G  ++     D    V++T      FGE+++++NM R  +V 
Sbjct: 558 QFIIRQHDDPLDFYILKDGEVNIYYNNAD---NVINTLSAYSFFGEISIIFNMLRTCNVA 614

Query: 431 AQTAGAL-WAMDRHTFRRILLKSAFKK 508
            ++  A+ +++    F  +L K   K+
Sbjct: 615 VKSDKAICYSISSEYFLSLLNKDIVKE 641


>UniRef50_UPI00006CA698 Cluster: cation channel family protein; n=2;
           Tetrahymena thermophila SB210|Rep: cation channel family
           protein - Tetrahymena thermophila SB210
          Length = 2774

 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 27/111 (24%), Positives = 59/111 (53%)
 Frame = +2

Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
           V+ + +F    A+ + ++L  M+ + +   ++V++ G+   +FY++  G  +++    D+
Sbjct: 264 VQNVQIFNLGQAEFVAKMLKKMYPQVAVKDDFVLKMGESAQDFYILAKGRVEIV--NQDK 321

Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLK 493
            ++V+   E    FGE+A++ N  R   V+AQT      + +  F +IL K
Sbjct: 322 -KQVIRVLEPGAYFGEVAILINQYRTCYVKAQTDCIFMCIKKDDFLKILNK 371



 Score = 41.9 bits (94), Expect = 0.008
 Identities = 26/89 (29%), Positives = 47/89 (52%), Gaps = 2/89 (2%)
 Frame = +2

Query: 248  GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMP--RAA 421
            GE+V ++GD     Y IE GV  + V  ++  E+V+      G FG L  +  +P  R  
Sbjct: 828  GEFVFQKGDLAQEIYFIEEGVVQI-VNNNNNNEEVLAEISQYGYFGGLEFINIVPSLRKI 886

Query: 422  SVRAQTAGALWAMDRHTFRRILLKSAFKK 508
            S++A+T  +L+ ++   + ++L +  F K
Sbjct: 887  SIKAKTNTSLFMLELDQYYQLLEEYPFAK 915


>UniRef50_Q09BB3 Cluster: PKA regulatory subunit-like protein; n=1;
           Stigmatella aurantiaca DW4/3-1|Rep: PKA regulatory
           subunit-like protein - Stigmatella aurantiaca DW4/3-1
          Length = 415

 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 32/114 (28%), Positives = 56/114 (49%), Gaps = 1/114 (0%)
 Frame = +2

Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEP-GEYVIRQGDDGDNFYVIENGVFDVLV 325
           L++ +    LFR L  +Q ++ +   F+  S P G+ ++ QG   D  Y++ NG   V++
Sbjct: 263 LSQTISTHALFRGLSREQ-KEAMTRDFQLCSVPVGKTLVEQGQPVDALYLLLNGHCQVVL 321

Query: 326 TGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
             D      +   E    FGE++++ N+P   +VRA +   L  +DR    R L
Sbjct: 322 DEDTERASPLPALEEGDVFGEISMLLNVPATVTVRADSRCTLLRLDREACERHL 375


>UniRef50_A0YLS1 Cluster: Putative uncharacterized protein; n=1;
           Lyngbya sp. PCC 8106|Rep: Putative uncharacterized
           protein - Lyngbya sp. PCC 8106
          Length = 486

 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 25/122 (20%), Positives = 61/122 (50%)
 Frame = +2

Query: 122 PKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIE 301
           P    Q   L + ++ ++ F +    ++  +++  + +     +++  +GD GD F++I 
Sbjct: 314 PVYSPQDLSLRDLLKKVVYFENFSNLEILSLIEKGYRQTYYSEQFIFHEGDPGDAFHIIL 373

Query: 302 NGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481
           +G  +++    ++  K +        FGEL+L+  + R+A VRA+    ++ + R+ F+ 
Sbjct: 374 SGSVEIIA---EKANKHIRDLYAGDFFGELSLLMGIRRSAGVRAKEKTIVFVVSRNIFQN 430

Query: 482 IL 487
            L
Sbjct: 431 FL 432


>UniRef50_Q7K3Z6 Cluster: GH01501p; n=4; Diptera|Rep: GH01501p -
           Drosophila melanogaster (Fruit fly)
          Length = 861

 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 29/89 (32%), Positives = 50/89 (56%), Gaps = 1/89 (1%)
 Frame = +2

Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403
           +FE  ++ G  +  QGD+G ++Y++  G  DV++ G    +  V T +    FG+LAL+ 
Sbjct: 224 VFEAHAQAGTILFNQGDEGRSWYILLKGSVDVVIHG----KGTVATLKTGDDFGKLALIN 279

Query: 404 NMPRAASVRAQTAGA-LWAMDRHTFRRIL 487
           + PRAA++  +     L  +D+  F RIL
Sbjct: 280 DAPRAATIVLKENNCHLLRVDKEHFNRIL 308


>UniRef50_Q23EB4 Cluster: ABC transporter family protein; n=3;
            Tetrahymena thermophila SB210|Rep: ABC transporter family
            protein - Tetrahymena thermophila SB210
          Length = 2778

 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 2/113 (1%)
 Frame = +2

Query: 155  EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV--T 328
            + ++   +F     Q + +++  M E    PGE + ++GD  D+ Y+I +G  ++ +  T
Sbjct: 2226 KTIQKFKIFNCFHQQTINKIIFQMKEITVSPGEAIFQEGDLDDSIYLILSGQIEIFLKET 2285

Query: 329  GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
              D    ++ T      FGE+A     PR AS R+     L  ++R  F +++
Sbjct: 2286 KRDSHSFILKTLSTDQIFGEIAFFSEQPRTASARSTCFSTLCKIERKDFIQVI 2338


>UniRef50_Q4WI41 Cluster: Cyclic nucleotide-binding domain protein;
           n=5; Eurotiomycetidae|Rep: Cyclic nucleotide-binding
           domain protein - Aspergillus fumigatus (Sartorya
           fumigata)
          Length = 900

 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 31/113 (27%), Positives = 54/113 (47%)
 Frame = +2

Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 328
           L + +R   LF+S     + +V   +  + S P +Y++ +GD+    Y +  G   V  T
Sbjct: 54  LIDRLRSFPLFQSTPESFLVEVAQHLRPQLSAPNDYILTEGDEAKAIYWLVRGA--VSAT 111

Query: 329 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
             D  E +    E    FGE+ ++ + PR A++ A+T   L  + +  FR IL
Sbjct: 112 SRDG-ESIYADLEPGAFFGEIGVLMDRPRTATIIARTRCLLVVLSKEDFRNIL 163


>UniRef50_A1CZ15 Cluster: Cyclic nucleotide-binding domain protein;
           n=22; Pezizomycotina|Rep: Cyclic nucleotide-binding
           domain protein - Neosartorya fischeri (strain ATCC 1020
           / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain
           ATCC 1020 / DSM 3700 / NRRL 181))
          Length = 920

 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 31/113 (27%), Positives = 54/113 (47%)
 Frame = +2

Query: 149 LAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVT 328
           L + +R   LF+S     + +V   +  + S P +Y++ +GD+    Y +  G   V  T
Sbjct: 54  LIDRLRSFPLFQSTPESFLVEVAQHLRPQLSAPNDYILTEGDEAKAIYWLVRGA--VSAT 111

Query: 329 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
             D  E +    E    FGE+ ++ + PR A++ A+T   L  + +  FR IL
Sbjct: 112 SRDG-ESIYADLEPGAFFGEIGVLMDRPRTATIIARTRCLLVVLSKEDFRNIL 163


>UniRef50_UPI000038CAE7 Cluster: COG1012: NAD-dependent aldehyde
           dehydrogenases; n=1; Nostoc punctiforme PCC 73102|Rep:
           COG1012: NAD-dependent aldehyde dehydrogenases - Nostoc
           punctiforme PCC 73102
          Length = 639

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 25/79 (31%), Positives = 43/79 (54%), Gaps = 1/79 (1%)
 Frame = +2

Query: 206 QQVLDAMFEKRS-EPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF 382
           Q VL+ + +  S   G Y+ ++G   D+ Y++E G+  +    +     VV+  E    F
Sbjct: 20  QMVLEKIMQPVSFSAGTYIFKEGSFADSCYILEEGIVRIETASESSSNFVVNYLEAGTIF 79

Query: 383 GELALMYNMPRAASVRAQT 439
           GE++L+  MPR+A+  AQT
Sbjct: 80  GEISLLDKMPRSATAYAQT 98


>UniRef50_Q6MJQ6 Cluster: Hyperpolarization-activated, cyclic
           nucleotide-gated K+; n=1; Bdellovibrio
           bacteriovorus|Rep: Hyperpolarization-activated, cyclic
           nucleotide-gated K+ - Bdellovibrio bacteriovorus
          Length = 130

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 27/90 (30%), Positives = 52/90 (57%), Gaps = 1/90 (1%)
 Frame = +2

Query: 221 AMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKV-VHTYEGSGSFGELAL 397
           A+ ++  +PG+++  +GD  ++FY++E+GV  +  T D   +++ +       SFGE AL
Sbjct: 6   AIVKETYKPGDFIFFEGDIENHFYIVESGVVSIF-TKDQMGKRIPICDIVDGESFGEFAL 64

Query: 398 MYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
           +   PR+AS +A T   L  +    F+++L
Sbjct: 65  ISKSPRSASAQAVTDVVLVKVSEEGFQQLL 94


>UniRef50_A3YU63 Cluster: Possible mechanosensitive ion channel;
           n=1; Synechococcus sp. WH 5701|Rep: Possible
           mechanosensitive ion channel - Synechococcus sp. WH 5701
          Length = 492

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 30/107 (28%), Positives = 55/107 (51%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
           LF  L  ++M Q+       R  PGE V+R+G+ GD+ + +  G+ +VL   ++     V
Sbjct: 340 LFGDLSEEEMLQLARNTRCLRFAPGEVVVREGNRGDSLFQVVQGMVEVLKNQEEEEPFQV 399

Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKS 496
              +    FGE++++    R+A+VRA     L  + R +   +LL++
Sbjct: 400 ACLKPGDVFGEMSMLAGSQRSATVRALDECLLLEVSRTSLGPLLLQN 446


>UniRef50_A3EYY6 Cluster: Tetrameric potassium-selective cyclic
            nucleotide gated channel; n=4; Eumetazoa|Rep: Tetrameric
            potassium-selective cyclic nucleotide gated channel -
            Strongylocentrotus purpuratus (Purple sea urchin)
          Length = 2238

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 32/107 (29%), Positives = 54/107 (50%), Gaps = 1/107 (0%)
 Frame = +2

Query: 170  ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL-VTGDDRVE 346
            + LFR  D   ++ +   +      P + ++RQGD GD  Y I  GV + L V    RV 
Sbjct: 2097 VALFREADEAFLRALSLMLKPVLFMPNDLIVRQGDVGDEMYFICRGVVEELEVNSHSRVA 2156

Query: 347  KVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
            +V+ T E      ++ L+Y++PR  S RA+T   + ++  H  + +L
Sbjct: 2157 RVLETGE---FLDDINLLYDVPRRTSYRARTHVDVLSLSVHDLKSVL 2200



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 24/79 (30%), Positives = 45/79 (56%)
 Frame = +2

Query: 251  EYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVR 430
            EY++R+ D G   + I  G+ +V V+ D  +  V  T +    FGE++L+++ PR AS+R
Sbjct: 1489 EYIVRKHDFGKEMFFIHRGLVEV-VSEDGSI--VFDTMQAGRFFGEISLVFSCPRTASIR 1545

Query: 431  AQTAGALWAMDRHTFRRIL 487
            AQ    ++ +++     +L
Sbjct: 1546 AQNNVDMFVLNKEDLDEVL 1564



 Score = 42.7 bits (96), Expect = 0.005
 Identities = 31/112 (27%), Positives = 52/112 (46%), Gaps = 1/112 (0%)
 Frame = +2

Query: 155  EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
            E +  + LF+  D+  ++ +   +      PG+ ++ QGD G   Y I  G  +VL    
Sbjct: 908  ETLSKVPLFKECDSNFLRMLALKLHVFIFMPGDVIVYQGDMGREMYFIRRGTCEVLSKDG 967

Query: 335  DRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
            + V   +    G G  FGE+ L++   R A+VRA +   L  + R    R+L
Sbjct: 968  NHVMSNI----GPGQYFGEVGLIFGDYRTATVRAASYCELLMLKRVDLDRVL 1015



 Score = 39.5 bits (88), Expect = 0.045
 Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 5/94 (5%)
 Frame = +2

Query: 224 MFEKRSEPGEYVIRQGDDGDN-----FYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGE 388
           M     +P  Y+ RQ   G N      Y I+ G  +VL   DD    +     G   FGE
Sbjct: 381 MLSLEIKPSLYLPRQKIAGRNEICHDMYFIQRGEIEVLSADDDDTP-IARLNHGK-LFGE 438

Query: 389 LALMYNMPRAASVRAQTAGALWAMDRHTFRRILL 490
           ++L+++MPR  ++RA     L  +D+   + +LL
Sbjct: 439 VSLIFSMPRTNTIRAAAHCDLLVLDKGDLQNVLL 472


>UniRef50_Q10898 Cluster: Uncharacterized protein Rv0104/MT0113;
           n=8; Mycobacterium tuberculosis complex|Rep:
           Uncharacterized protein Rv0104/MT0113 - Mycobacterium
           tuberculosis
          Length = 504

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 29/76 (38%), Positives = 39/76 (51%)
 Frame = +2

Query: 248 GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASV 427
           G  + RQG+  D+F+VIE+G  + LV G     KV+        FGE  L+  M R A+V
Sbjct: 401 GYTLFRQGERADHFFVIESGELEALVDG-----KVILRLGAGDHFGEACLLGGMRRIATV 455

Query: 428 RAQTAGALWAMDRHTF 475
           RA     LW +D   F
Sbjct: 456 RACEPSVLWELDGKAF 471


>UniRef50_UPI00006D001F Cluster: cyclic nucleotide-binding domain
           containing protein; n=1; Tetrahymena thermophila
           SB210|Rep: cyclic nucleotide-binding domain containing
           protein - Tetrahymena thermophila SB210
          Length = 705

 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 27/109 (24%), Positives = 56/109 (51%), Gaps = 2/109 (1%)
 Frame = +2

Query: 173 LLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGD-NFYVIENGVFDVLVTG-DDRVE 346
           L   +   + +++++  M E    P E + +Q +  D + Y I++G+ ++ V+   ++ E
Sbjct: 120 LFIANFSQKVIKEIIFLMEEIIVAPNEIIFKQCEAEDQSIYFIQSGLVEIFVSNTQEQSE 179

Query: 347 KVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLK 493
           KV+   E    FGE++    +PR AS R+     ++ ++R  F  +L K
Sbjct: 180 KVITQLEQDSMFGEISFFSGLPRTASARSLKLSTIYQINREKFLNLLKK 228


>UniRef50_Q131K0 Cluster: Cyclic nucleotide-binding precursor; n=1;
           Rhodopseudomonas palustris BisB5|Rep: Cyclic
           nucleotide-binding precursor - Rhodopseudomonas
           palustris (strain BisB5)
          Length = 367

 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 36/113 (31%), Positives = 54/113 (47%)
 Frame = +2

Query: 146 RLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV 325
           R  E V  +  FR L A  +  ++  +  +    G  V+R+G+ GD  Y I +G   V V
Sbjct: 235 RTWELVISVPFFRDLGAAAVADIVRLLQARDVNAGTVVVREGEPGDAMYFIVSGEATVRV 294

Query: 326 TGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484
                  K V    GS  FGE+AL++N PR+A+V A     L  +D   F ++
Sbjct: 295 A-----PKPVVLGPGS-FFGEMALLFNTPRSATVVATQPSVLLVLDIADFHQL 341


>UniRef50_Q5CD46 Cluster: PKA regulatory subunit homologous protein;
           n=6; Myxococcales|Rep: PKA regulatory subunit homologous
           protein - Myxococcus xanthus
          Length = 405

 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 38/119 (31%), Positives = 56/119 (47%), Gaps = 2/119 (1%)
 Frame = +2

Query: 140 RARLAE-AVRGILLFRSLDAQQMQQVLDAMFEKRS-EPGEYVIRQGDDGDNFYVIENGVF 313
           R R+ E  +R   LF  L   Q   V    FE RS   GE ++ QG  GD FYV+  G  
Sbjct: 251 RRRMVENLLRSNPLFNQLSPAQKAAV-SRDFELRSFAAGEALMTQGQPGDAFYVLLRGRC 309

Query: 314 DVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILL 490
              +         +        FGE++L+ + P +A+VRA  AG +  ++R  F++ LL
Sbjct: 310 TPWLEQPHGRRVALSALREGDVFGEISLLLDKPVSATVRADVAGVVLRLERDAFQKHLL 368



 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 31/113 (27%), Positives = 53/113 (46%), Gaps = 1/113 (0%)
 Frame = +2

Query: 131 DAQRARLAE-AVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG 307
           +A RA +AE    G+ +   +  +    +L+ +  +   PG+ V+ +G  G + + +  G
Sbjct: 117 EATRAHVAEDGATGLPILSQVSRETFVALLEVLQVRAFFPGQTVVEEGTPGASMFALVEG 176

Query: 308 VFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDR 466
             DV+   +D   + V T      FGELAL+   PR A+V A     L  + R
Sbjct: 177 RADVVRALEDGQRRSVGTVTPGDFFGELALISEGPRLATVVATERAVLLELTR 229


>UniRef50_A6G0I3 Cluster: Putative uncharacterized protein; n=1;
           Plesiocystis pacifica SIR-1|Rep: Putative
           uncharacterized protein - Plesiocystis pacifica SIR-1
          Length = 428

 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 27/80 (33%), Positives = 42/80 (52%)
 Frame = +2

Query: 242 EPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAA 421
           EPGE +I++G+  +  YVI +G  +V   GDD  E+ +   +    FGE A+   + R A
Sbjct: 326 EPGEVIIQEGEVAETAYVIIDGSCEVSRVGDDGGEQRLRVMDAGEVFGETAIFAGVRRTA 385

Query: 422 SVRAQTAGALWAMDRHTFRR 481
           +VRA     +  + R  F R
Sbjct: 386 TVRALEPTKVGVITRDLFER 405


>UniRef50_UPI00006CA699 Cluster: cyclic nucleotide-binding domain
           containing protein; n=1; Tetrahymena thermophila
           SB210|Rep: cyclic nucleotide-binding domain containing
           protein - Tetrahymena thermophila SB210
          Length = 2731

 Score = 50.0 bits (114), Expect = 3e-05
 Identities = 32/112 (28%), Positives = 58/112 (51%), Gaps = 1/112 (0%)
 Frame = +2

Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
           E +  + +F     Q + +++  +  K +   +Y+I+ G+  + FY+I  G  ++L  G 
Sbjct: 232 ELISNVQIFNLGSPQFVLKMIKKLHPKVAVKDDYIIKIGEIAEEFYIISKGKVEML--GG 289

Query: 335 DRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
           D+  K V+    SGS FGE+ ++ N  R   VRAQT   L  + +  F ++L
Sbjct: 290 DK--KTVNRILESGSYFGEVGILLNQYRTCYVRAQTDCILMCIKKEDFLQLL 339



 Score = 48.8 bits (111), Expect = 7e-05
 Identities = 30/97 (30%), Positives = 49/97 (50%), Gaps = 3/97 (3%)
 Frame = +2

Query: 227 FEKRSEP-GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403
           FEK   P GE+V ++GD     Y IE G+  ++   DD  E+++     +  FG L  + 
Sbjct: 692 FEKILVPRGEFVFQKGDLAQEMYFIEEGIIQIVKFNDDLKEEILGEIYKNSYFGGLEFIN 751

Query: 404 NMP--RAASVRAQTAGALWAMDRHTFRRILLKSAFKK 508
            +P  R  SVRA+T   L+ +   ++  I+ +  F K
Sbjct: 752 KVPTLRKVSVRAKTNACLYMLKMQSYIDIVQEYPFCK 788


>UniRef50_UPI000065D7C1 Cluster: Homolog of Oncorhynchus mykiss
           "Hyperpolarization-activated cyclic nucleotide-gated
           cation channel 1.; n=1; Takifugu rubripes|Rep: Homolog
           of Oncorhynchus mykiss "Hyperpolarization-activated
           cyclic nucleotide-gated cation channel 1. - Takifugu
           rubripes
          Length = 783

 Score = 50.0 bits (114), Expect = 3e-05
 Identities = 30/117 (25%), Positives = 60/117 (51%)
 Frame = +2

Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
           V  + LF + D   +  +L  +  +  +P +Y++R+G  G   + I++GV  +L  G+  
Sbjct: 391 VASMPLFANADPNFVTAMLTKLRFEVFQPKDYIVREGTIGKKMFFIQHGVVSILTKGNIS 450

Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511
           ++ +  +Y     FGE+ L+    R ASV+A+T   L+++    F  +L +    +R
Sbjct: 451 MKLMDGSY-----FGEICLLTRGRRTASVQAETYCRLYSLSVDNFNEVLEEYPMMRR 502


>UniRef50_Q98GM7 Cluster: Mlr3256 protein; n=2;
           Alphaproteobacteria|Rep: Mlr3256 protein - Rhizobium
           loti (Mesorhizobium loti)
          Length = 151

 Score = 50.0 bits (114), Expect = 3e-05
 Identities = 29/80 (36%), Positives = 43/80 (53%)
 Frame = +2

Query: 248 GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASV 427
           G+ + RQGD+GD  YVI +G  D+LV  D    KV      S   GE+A++ N  R A+V
Sbjct: 39  GQILFRQGDEGDAAYVILSGKADILVESDSGPIKVAELVPNS-IVGEIAILCNSSRTATV 97

Query: 428 RAQTAGALWAMDRHTFRRIL 487
           RA +      + +  F R++
Sbjct: 98  RAASPLEALRIPKDHFLRLM 117


>UniRef50_Q2LPZ1 Cluster: Cyclic nucleotide-binding domain protein;
           n=1; Syntrophus aciditrophicus SB|Rep: Cyclic
           nucleotide-binding domain protein - Syntrophus
           aciditrophicus (strain SB)
          Length = 229

 Score = 50.0 bits (114), Expect = 3e-05
 Identities = 28/114 (24%), Positives = 50/114 (43%)
 Frame = +2

Query: 146 RLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV 325
           ++ E +  I LF  L  QQ+ ++     ++  + G+ +  +GD+G  FY++ +G   V  
Sbjct: 3   KVLEIIGSIPLFNGLSEQQLGEIRGIARDRFYDKGKEIFAEGDEGGGFYIVASGQVKVFK 62

Query: 326 TGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
              +  E ++H Y    SFGE+ +       AS        L    R  F  +L
Sbjct: 63  LSPEGKEHILHIYGPGHSFGEVPVFSGERFPASAETLLKSHLLFFPRTDFVALL 116


>UniRef50_Q1D5Q4 Cluster: Cyclic nucleotide-binding domain protein;
           n=1; Myxococcus xanthus DK 1622|Rep: Cyclic
           nucleotide-binding domain protein - Myxococcus xanthus
           (strain DK 1622)
          Length = 715

 Score = 50.0 bits (114), Expect = 3e-05
 Identities = 32/93 (34%), Positives = 46/93 (49%)
 Frame = +2

Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
           +A+  I LF  L      ++ +    +R  P E +I QG  GD FYVI  G   V  T +
Sbjct: 442 DALPTIPLFSDLPRDAFIELFERCPLRRFGPDERIIDQGSHGDAFYVICEGAVRVFRTEE 501

Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 433
            + + +  T EG   FGE+AL+    R ASV +
Sbjct: 502 GQRQDIA-TLEGGTFFGEMALLSGAARTASVES 533



 Score = 37.1 bits (82), Expect = 0.24
 Identities = 27/104 (25%), Positives = 45/104 (43%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
           LFR    +  + +++    +  E    +IR GD  D  YV+ +G  +V   G      + 
Sbjct: 580 LFRLFGRKDRRALVERFRSRDVERDTVIIRDGDPTDGLYVVLSGEVEVRKDG----HLLT 635

Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
              EG   FGE++L+   P  A+V A     L  + R  F  ++
Sbjct: 636 QLREGD-VFGEISLLQKTPATATVTATRHTTLLRLPRADFDALI 678


>UniRef50_Q08NQ8 Cluster: Protein phosphatase 1; n=2;
           Cystobacterineae|Rep: Protein phosphatase 1 -
           Stigmatella aurantiaca DW4/3-1
          Length = 470

 Score = 49.6 bits (113), Expect = 4e-05
 Identities = 36/111 (32%), Positives = 56/111 (50%)
 Frame = +2

Query: 101 EGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDG 280
           +GA A    S+AQ +R+ EA+R I LFR L  ++   VL     +    G  ++ +G  G
Sbjct: 301 DGAVASEETSEAQ-SRM-EALRKIPLFRHLTYKEQTAVLSIATTRTFPAGREIVVEGQPG 358

Query: 281 DNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 433
           +  +V+  G   +   G +  E         G FGE+ L+ N PR+A+VRA
Sbjct: 359 EELFVVIRGRVVIEKNGVEIAE-----LRAGGHFGEMGLIDNAPRSATVRA 404


>UniRef50_A0YM45 Cluster: Sulfate transporter family protein; n=1;
           Lyngbya sp. PCC 8106|Rep: Sulfate transporter family
           protein - Lyngbya sp. PCC 8106
          Length = 759

 Score = 49.6 bits (113), Expect = 4e-05
 Identities = 27/98 (27%), Positives = 44/98 (44%)
 Frame = +2

Query: 191 DAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEG 370
           D+QQ+  ++  +   +  P E++ R GD  D  Y +E G   V+        K V TY  
Sbjct: 627 DSQQVIMLMKYLKLLQISPDEFIFRTGDLADGLYFVETGQVSVIFELPTGQMKRVQTYYS 686

Query: 371 SGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484
               GE+    N+PR AS+ A     L+ +    F ++
Sbjct: 687 GTILGEIGHYMNVPRTASIIADQPSRLYYLSTQAFEQM 724


>UniRef50_Q23WN2 Cluster: Cyclic nucleotide-binding domain
           containing protein; n=1; Tetrahymena thermophila
           SB210|Rep: Cyclic nucleotide-binding domain containing
           protein - Tetrahymena thermophila SB210
          Length = 1010

 Score = 49.6 bits (113), Expect = 4e-05
 Identities = 26/69 (37%), Positives = 39/69 (56%)
 Frame = +2

Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403
           M  +R   G+ V  QGD G  FY+I  G+  + +   +  +KV     G  SFGELAL+ 
Sbjct: 61  MTYERFNSGDMVFSQGDRGSKFYIILEGLVGIYIKIKNEQKKVKELSRGE-SFGELALIN 119

Query: 404 NMPRAASVR 430
           + PR+AS++
Sbjct: 120 DAPRSASIK 128


>UniRef50_P63401 Cluster: Uncharacterized ABC transporter
           ATP-binding protein Rv2564/MT2640; n=14; Mycobacterium
           tuberculosis complex|Rep: Uncharacterized ABC
           transporter ATP-binding protein Rv2564/MT2640 -
           Mycobacterium tuberculosis
          Length = 330

 Score = 49.6 bits (113), Expect = 4e-05
 Identities = 25/80 (31%), Positives = 42/80 (52%)
 Frame = +2

Query: 248 GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASV 427
           GE +  Q   GD  YV+  G F+++    D  E++V T      FGE+ +++++PR+A+V
Sbjct: 234 GEVLFEQSTMGDLIYVVSEGEFEIVRELADGGEELVKTAAPGDYFGEIGVLFHLPRSATV 293

Query: 428 RAQTAGALWAMDRHTFRRIL 487
           RA++           FR  L
Sbjct: 294 RARSDATAVGYTAQAFRERL 313


>UniRef50_UPI00006CC0E9 Cluster: cation channel family protein; n=1;
           Tetrahymena thermophila SB210|Rep: cation channel family
           protein - Tetrahymena thermophila SB210
          Length = 1238

 Score = 49.2 bits (112), Expect = 6e-05
 Identities = 27/100 (27%), Positives = 51/100 (51%), Gaps = 5/100 (5%)
 Frame = +2

Query: 203 MQQVLDAMFEKRSEPGEYVIRQGDDGD-NFYVIENGVFDVLVT----GDDRVEKVVHTYE 367
           +++ +  + EKR  P E + RQ D GD N Y I +G   + +     G ++  +++ + +
Sbjct: 496 LERTVSIIKEKRYYPEEIIFRQNDTGDSNIYFIASGQVQIYIEASYPGGEKKVQILQSLQ 555

Query: 368 GSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
              SFG  +     PR  +VR Q    L +++R++F  +L
Sbjct: 556 SGQSFGHYSFFTGQPRMVNVRTQGFVTLLSINRNSFINLL 595


>UniRef50_Q2YZI3 Cluster: Putative uncharacterized protein; n=1;
           uncultured gamma proteobacterium|Rep: Putative
           uncharacterized protein - uncultured gamma
           proteobacterium
          Length = 354

 Score = 49.2 bits (112), Expect = 6e-05
 Identities = 30/111 (27%), Positives = 57/111 (51%), Gaps = 1/111 (0%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL-VTGDDRVEKV 352
           +F+ +    +Q +   M     + GE VIRQG++G++FY+I +G   V+  T  +    V
Sbjct: 149 VFQRIPPGNIQSIFIRMQTHHFKAGEAVIRQGEEGEHFYIIRDGHCRVIRKTRKNPEGMV 208

Query: 353 VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFK 505
           +   +   +FGE +L+    R AS+  ++ G L ++ +  F  +L +   K
Sbjct: 209 LARLKAGDNFGEESLISGGKRNASIVMESDGVLMSLSKTDFLELLNEPLLK 259


>UniRef50_Q1PUQ2 Cluster: Similar to transcriptional regulator of
           Crp/Fnr family; n=1; Candidatus Kuenenia
           stuttgartiensis|Rep: Similar to transcriptional
           regulator of Crp/Fnr family - Candidatus Kuenenia
           stuttgartiensis
          Length = 228

 Score = 49.2 bits (112), Expect = 6e-05
 Identities = 27/109 (24%), Positives = 51/109 (46%)
 Frame = +2

Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
           ++ + LF SL  +Q++ +  A   K       +  Q D GD FY++  G   + +  +D 
Sbjct: 10  LKNVPLFNSLANEQLKTLFRAGITKSFPKDHVIFYQHDHGDTFYIVITGKVKITLLNEDG 69

Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
            E V+   +    FGE++LM +  R+ S        L+   R+ F +++
Sbjct: 70  KEIVLSLLKEGDFFGEMSLMDDETRSVSAVCVENTTLFLFTRNQFHKLI 118


>UniRef50_A4M043 Cluster: Transcriptional regulator, Crp/Fnr family;
           n=1; Geobacter bemidjiensis Bem|Rep: Transcriptional
           regulator, Crp/Fnr family - Geobacter bemidjiensis Bem
          Length = 238

 Score = 49.2 bits (112), Expect = 6e-05
 Identities = 28/110 (25%), Positives = 51/110 (46%)
 Frame = +2

Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
           +R I LF  LD  +  +V   + EKR    + V+ + D  +  Y++  G   V+  G + 
Sbjct: 18  LRAIPLFSCLDPLEFSEVQRRIMEKRFHKNQVVLLEEDTANYMYIVYGGKVRVVHLGSEG 77

Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILL 490
            E+++  ++    FGE+AL+      A+V A     +  + + TF    L
Sbjct: 78  SERILAVHKRGDVFGEMALLDAKTAPATVIAMEDAEIGLLSKETFDTFFL 127


>UniRef50_Q4D6P2 Cluster: Regulatory subunit of protein kinase
           a-like protein, putative; n=2; Trypanosoma cruzi|Rep:
           Regulatory subunit of protein kinase a-like protein,
           putative - Trypanosoma cruzi
          Length = 558

 Score = 49.2 bits (112), Expect = 6e-05
 Identities = 36/155 (23%), Positives = 70/155 (45%)
 Frame = +2

Query: 50  RKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMF 229
           R  + A +   EE  S E   A   KS    + + + +    LF  LD +++ ++   M 
Sbjct: 237 RLGISARSIGAEEMMSTEFPTAA--KSSEAASFIMKVLEKHFLFSFLDDKELHKLAMVMN 294

Query: 230 EKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNM 409
            +    G  V+ +G+    FY+I +G   + +  DD       + +    FGEL L+Y  
Sbjct: 295 TEDFPEGIKVLVKGETNSKFYIILDGSATITMFEDDPDRIETESLQKGSVFGELGLLYET 354

Query: 410 PRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
               SV + T      ++R+T++ ++ ++  +KR+
Sbjct: 355 QSEVSVESTTPLFCATLERNTYKIVVSRAEEEKRQ 389



 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 30/120 (25%), Positives = 56/120 (46%), Gaps = 1/120 (0%)
 Frame = +2

Query: 131 DAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGV 310
           + +R R    +      + L AQ+  ++ +A+ E +   G+ +IR G+  D  ++I  G 
Sbjct: 385 EEKRQRYFSFLENAPFIKDLPAQERLKIAEALKEDKYTEGDKIIRYGEKVDWLHIIVEGT 444

Query: 311 FDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWA-MDRHTFRRIL 487
            DV+   ++  E+ V T      FG+L  +Y+    A V A +     A M R  F +++
Sbjct: 445 ADVIGRNEEGEEEYVVTKNAGECFGDLEFLYHHETVADVVATSPFVRTAKMSRLHFEQLI 504


>UniRef50_Q22R60 Cluster: Cyclic nucleotide-binding domain
           containing protein; n=1; Tetrahymena thermophila
           SB210|Rep: Cyclic nucleotide-binding domain containing
           protein - Tetrahymena thermophila SB210
          Length = 863

 Score = 49.2 bits (112), Expect = 6e-05
 Identities = 26/77 (33%), Positives = 42/77 (54%)
 Frame = +2

Query: 257 VIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQ 436
           VI  G+ GD FY+I  G+ ++ V         V   +   SFGELAL+ + PR A+++AQ
Sbjct: 86  VIVHGERGDKFYIILQGICEIYVPNSQGQFVKVGELKAGQSFGELALINDSPRRATIKAQ 145

Query: 437 TAGALWAMDRHTFRRIL 487
           T   L  + +  + +I+
Sbjct: 146 TDCDLAILSKKDYIKII 162


>UniRef50_Q8WZA2 Cluster: Rap guanine nucleotide exchange factor 4;
           n=53; Coelomata|Rep: Rap guanine nucleotide exchange
           factor 4 - Homo sapiens (Human)
          Length = 1011

 Score = 49.2 bits (112), Expect = 6e-05
 Identities = 29/89 (32%), Positives = 49/89 (55%), Gaps = 1/89 (1%)
 Frame = +2

Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403
           +FE  ++ G  +  QG++G ++Y+I  G  +V++ G    + VV T      FG+LAL+ 
Sbjct: 373 IFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYG----KGVVCTLHEGDDFGKLALVN 428

Query: 404 NMPRAASVRAQTAGA-LWAMDRHTFRRIL 487
           + PRAAS+  +        +D+  F RIL
Sbjct: 429 DAPRAASIVLREDNCHFLRVDKEDFNRIL 457



 Score = 38.7 bits (86), Expect = 0.078
 Identities = 26/110 (23%), Positives = 51/110 (46%), Gaps = 2/110 (1%)
 Frame = +2

Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV--TGD 334
           ++ +  F       + Q+    + +  E G  + RQGD G N+Y +  G  DV V  T  
Sbjct: 38  LKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSS 97

Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484
            +    + T     +FGE +++ N PR A++  + +  L  +++  F+ +
Sbjct: 98  HQDAVTICTLGIGTAFGE-SILDNTPRHATIVTRESSELLRIEQKDFKAL 146


>UniRef50_Q9P1Z3 Cluster: Potassium/sodium
           hyperpolarization-activated cyclic nucleotide-gated
           channel 3; n=61; Eukaryota|Rep: Potassium/sodium
           hyperpolarization-activated cyclic nucleotide-gated
           channel 3 - Homo sapiens (Human)
          Length = 774

 Score = 49.2 bits (112), Expect = 6e-05
 Identities = 34/112 (30%), Positives = 54/112 (48%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
           LF   D   +  VL  +  +  +PG+ V+R+G  G   Y I++G+  VL  G     +  
Sbjct: 428 LFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLARG----ARDT 483

Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511
              +GS  FGE+ L+    R ASVRA T   L+++    F  +L +    +R
Sbjct: 484 RLTDGS-YFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRR 534


>UniRef50_Q1GWA6 Cluster: Cyclic nucleotide-binding protein
           precursor; n=4; Sphingomonadales|Rep: Cyclic
           nucleotide-binding protein precursor - Sphingopyxis
           alaskensis (Sphingomonas alaskensis)
          Length = 811

 Score = 48.8 bits (111), Expect = 7e-05
 Identities = 30/101 (29%), Positives = 56/101 (55%), Gaps = 1/101 (0%)
 Frame = +2

Query: 188 LDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYE 367
           L A+ +  V++A   +R   G+ V+ +G+ GD+ YVI +G   ++V  D   + +   Y 
Sbjct: 478 LTAEDLAPVVEAAEVERVPAGKAVLIEGEQGDDVYVIRSG--SMVVEKDIGGKPIFLRYL 535

Query: 368 GSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
            +GS FGE+ ++   PR A+V+A     +  +   +FR++L
Sbjct: 536 PAGSFFGEMGVLSGEPRNATVKAAVGSEVIKLTGDSFRKML 576


>UniRef50_Q0VMY3 Cluster: CAMP-dependent protein kinase regulatory
           chain; n=1; Alcanivorax borkumensis SK2|Rep:
           CAMP-dependent protein kinase regulatory chain -
           Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM
           11573)
          Length = 355

 Score = 48.8 bits (111), Expect = 7e-05
 Identities = 32/127 (25%), Positives = 57/127 (44%)
 Frame = +2

Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 304
           + DA      +A+    LF ++    +  +     E+  + GE ++++GD GD  +VI+ 
Sbjct: 127 EDDANERDWMDALLSSELFSAVPPAMIHSLFVKFQEREVQLGEVIVKEGDHGDTLFVIKQ 186

Query: 305 GVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484
           G   V      + E +     G   FGE AL+   PR A++   + G L  + +  F+ I
Sbjct: 187 GKAMVTRIKGAKQETLAALSAGR-FFGEDALISESPRNATITMTSDGVLMCLGKSDFQAI 245

Query: 485 LLKSAFK 505
           L  S  +
Sbjct: 246 LQDSVIR 252


>UniRef50_A0YHV0 Cluster: Putative uncharacterized protein; n=1;
           marine gamma proteobacterium HTCC2143|Rep: Putative
           uncharacterized protein - marine gamma proteobacterium
           HTCC2143
          Length = 159

 Score = 48.8 bits (111), Expect = 7e-05
 Identities = 23/64 (35%), Positives = 39/64 (60%)
 Frame = +2

Query: 248 GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASV 427
           GE+   Q D GD+ +++E G  ++  T +  ++ V+ T      FGE+AL+   PR+A+V
Sbjct: 39  GEFFFHQNDKGDSLFLLEKGSAEIFKTFNG-IDYVLRTVNNGDCFGEMALIDFTPRSATV 97

Query: 428 RAQT 439
           RA+T
Sbjct: 98  RAKT 101


>UniRef50_Q00X68 Cluster: Cyclic nucleotide dependent protein
           kinase; n=3; Eukaryota|Rep: Cyclic nucleotide dependent
           protein kinase - Ostreococcus tauri
          Length = 1179

 Score = 48.8 bits (111), Expect = 7e-05
 Identities = 36/128 (28%), Positives = 62/128 (48%), Gaps = 5/128 (3%)
 Frame = +2

Query: 137 QRARLAEAVRGILLFR-SLDAQQMQQVLDAMFEKRSEPGEYVIRQGD----DGDNFYVIE 301
           +R RL   +  + +FR SLDA+ M  ++DA+ E   E G  ++   D    +   FYV+ 
Sbjct: 197 RRCRLTSYLDAVEVFRESLDARTMSMLVDALREVTFESGHVIVSPDDVYEEESSKFYVVI 256

Query: 302 NGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481
           +G  + +V  DD  +  V+       FGEL+L++     A V A    +   +D  +F R
Sbjct: 257 DG--EAVVYVDDGSKAEVNRLRRGDYFGELSLIHKTSPTAMVIAVGQVSALTLDAESFYR 314

Query: 482 ILLKSAFK 505
           ++ +   K
Sbjct: 315 MIGEKTVK 322



 Score = 43.6 bits (98), Expect = 0.003
 Identities = 21/51 (41%), Positives = 35/51 (68%), Gaps = 1/51 (1%)
 Frame = +2

Query: 362 YEGSGSFGELALMYNMPRAASVRAQTAGA-LWAMDRHTFRRILLKSAFKKR 511
           Y G  +FGE+AL+   PR A+V A+++   LWA+DR TF+  + ++ F++R
Sbjct: 149 YPGD-TFGEVALVRKCPRTATVIAESSSVKLWALDRATFQETVKRTTFERR 198



 Score = 39.9 bits (89), Expect = 0.034
 Identities = 21/74 (28%), Positives = 39/74 (52%), Gaps = 1/74 (1%)
 Frame = +2

Query: 89  DDSDEGAPA-VFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIR 265
           DD+DE A      +  ++    +EA+ G+ LFR L       +  ++ E   E G+ ++R
Sbjct: 17  DDADENARIRARARRVSEPESASEALDGVALFRELKRDARAALCGSVVECEYERGDVIVR 76

Query: 266 QGDDGDNFYVIENG 307
           + + G +FYV+ +G
Sbjct: 77  KNEVGTHFYVVAHG 90


>UniRef50_A4RUE3 Cluster: Predicted protein; n=1; Ostreococcus
           lucimarinus CCE9901|Rep: Predicted protein -
           Ostreococcus lucimarinus CCE9901
          Length = 121

 Score = 48.8 bits (111), Expect = 7e-05
 Identities = 36/120 (30%), Positives = 56/120 (46%), Gaps = 10/120 (8%)
 Frame = +2

Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENG-VF 313
           +R R    +  I +F  L + +   V+        +PGE +IRQG+  D FYVI  G   
Sbjct: 1   RRLRYERTLAKIPVFADLGSYERAMVVKQAKRFSFKPGEKIIRQGEVADKFYVILKGSAV 60

Query: 314 DVLVTGD-DRV--------EKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDR 466
                GD D V        ++++  +     FGELAL+   PR A++ A  +  + A+DR
Sbjct: 61  STKSDGDVDHVAPGSKIPPDRIMRNFSQGQYFGELALLTGQPRLATIVANDSLEVLAIDR 120


>UniRef50_Q23EB1 Cluster: Cation channel family protein; n=2;
           Tetrahymena thermophila SB210|Rep: Cation channel family
           protein - Tetrahymena thermophila SB210
          Length = 1130

 Score = 48.8 bits (111), Expect = 7e-05
 Identities = 27/106 (25%), Positives = 50/106 (47%), Gaps = 2/106 (1%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKV- 352
           +F     Q + +++  M E    PGE +  +GD  D+ Y+I +G   +L     +   + 
Sbjct: 609 IFNCFSQQSINKLVFQMKEIIVSPGEVIFSEGDRDDSIYLITSGQIQILQNTAQKSCSIF 668

Query: 353 -VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
            + T   +  FGE+A    MPR A+ ++     L+ ++R  F  I+
Sbjct: 669 QLKTLSENQIFGEIAFFSQMPRTATAKSLNLSTLYKIERKDFIEIV 714


>UniRef50_UPI00006CF9CA Cluster: cation channel family protein; n=1;
           Tetrahymena thermophila SB210|Rep: cation channel family
           protein - Tetrahymena thermophila SB210
          Length = 1108

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 35/118 (29%), Positives = 61/118 (51%), Gaps = 6/118 (5%)
 Frame = +2

Query: 176 LFRSLDAQQ-MQQVLDAMFEKRSEPGEYVIRQ----GDDGDNFYVIENGVFDVLVTGDDR 340
           LF   + +Q + Q+   + EK + P E +I Q    GDD  + Y I++G  ++     + 
Sbjct: 523 LFNQQNMEQFLFQISINLLEKITIPEEIIINQEESGGDDDQSMYFIQDGEVEIFYQHSN- 581

Query: 341 VEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511
             K +    G+GS FGE++   N+ R ASV++    +L+ + R  F +IL K   +K+
Sbjct: 582 -SKTILKKLGAGSYFGEISFFTNLQRTASVQSVNFASLYYLKRSEFIKILQKFPNQKK 638


>UniRef50_UPI00006A1C4D Cluster: Uncharacterized protein C20orf152.;
           n=2; Xenopus tropicalis|Rep: Uncharacterized protein
           C20orf152. - Xenopus tropicalis
          Length = 436

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 32/107 (29%), Positives = 55/107 (51%), Gaps = 4/107 (3%)
 Frame = +2

Query: 167 GILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL--VTGDDR 340
           GIL FR   +Q    +   ++ +R   G  ++R+G  GD+FY + +GV  V   V G   
Sbjct: 30  GILSFRRYSSQMQLMLARVVYYRRFGRGRVIVRKGHRGDSFYFVFSGVIAVTQDVDGSSA 89

Query: 341 V--EKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTF 475
           +   + +  ++G+ SFGE+AL+ ++ R A+V          +DR  F
Sbjct: 90  LLDPEPILLHKGA-SFGEVALLKDLRRNATVVCMEETEFLVVDRMEF 135


>UniRef50_UPI0000EC9E1A Cluster: Rap guanine nucleotide exchange
           factor 3 (cAMP-regulated guanine nucleotide exchange
           factor I) (cAMP-GEFI) (Exchange factor directly
           activated by cAMP 1) (Epac 1) (Rap1
           guanine-nucleotide-exchange factor directly activated by
           cAMP).; n=1; Gallus gallus|Rep: Rap guanine nucleotide
           exchange factor 3 (cAMP-regulated guanine nucleotide
           exchange factor I) (cAMP-GEFI) (Exchange factor directly
           activated by cAMP 1) (Epac 1) (Rap1
           guanine-nucleotide-exchange factor directly activated by
           cAMP). - Gallus gallus
          Length = 766

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 29/89 (32%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
 Frame = +2

Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403
           MFE     G  +  QGD G ++Y++  G  +V+  G    + +V T      FG+LAL+ 
Sbjct: 189 MFESHQRAGTVLFSQGDKGTSWYIVWKGSVNVVTHG----KGLVATLHEGDDFGQLALVN 244

Query: 404 NMPRAASVRAQTAGA-LWAMDRHTFRRIL 487
           + PRAAS+  +        +D+  F RIL
Sbjct: 245 DAPRAASIILREDNCHFLRVDKQDFNRIL 273


>UniRef50_Q1DAY2 Cluster: Cyclic nucleotide-binding domain protein;
           n=2; Cystobacterineae|Rep: Cyclic nucleotide-binding
           domain protein - Myxococcus xanthus (strain DK 1622)
          Length = 152

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 25/112 (22%), Positives = 53/112 (47%)
 Frame = +2

Query: 152 AEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTG 331
           A  ++ + LF  L   Q+ +V      +    G ++ R+G+ G   +VI  G   +  + 
Sbjct: 3   AAVLKKVALFEGLTQGQLAKVAQIGHSRTYPAGAFLFREGETGQEMFVIAEGKVRISKSV 62

Query: 332 DDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
               E+ +   E    FGE+A++ + PR+A   A  + ++W ++R    +++
Sbjct: 63  PGIGEEALAILEPGQYFGEMAVIEDSPRSADAIAHVSCSVWVIERSRLDQLM 114


>UniRef50_A6G5Y4 Cluster: Protein phosphatase/cyclic
           nucleotide-binding domain protein; n=1; Plesiocystis
           pacifica SIR-1|Rep: Protein phosphatase/cyclic
           nucleotide-binding domain protein - Plesiocystis
           pacifica SIR-1
          Length = 433

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 34/127 (26%), Positives = 58/127 (45%), Gaps = 3/127 (2%)
 Frame = +2

Query: 116 VFPKSDAQRARLA---EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDN 286
           V P  D +R ++    + +R I LF  L+  ++ ++      +    GE ++R+GD+ D 
Sbjct: 262 VRPADDQRRRQVVNNLQTLRHIALFMDLNDSELVRIFRRFQARDYGQGEVILREGDNADC 321

Query: 287 FYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDR 466
            +V+  G  DV V    R  K + T      FGE+ L+   PR+A+V          + R
Sbjct: 322 LFVLVEG--DVRV---GRAGKTLTTLSRGAHFGEMGLLNQRPRSATVTTLRPVHALVLGR 376

Query: 467 HTFRRIL 487
             F  +L
Sbjct: 377 DAFNEVL 383


>UniRef50_A0YCM5 Cluster: CAMP-binding protein-catabolite gene
           activator and regulatory subunit of cAMP-dependent
           protein kinase; n=2; unclassified
           Gammaproteobacteria|Rep: CAMP-binding protein-catabolite
           gene activator and regulatory subunit of cAMP-dependent
           protein kinase - marine gamma proteobacterium HTCC2143
          Length = 216

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 27/105 (25%), Positives = 51/105 (48%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
           +F  L  Q+++ +  +   +       +I + D  D+ Y+IE G   V  +  +  E ++
Sbjct: 8   IFEGLTPQELEVLASSGVMRTYPKNTVIINENDLADSLYIIETGRVKVYCSDKNGKEFIM 67

Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILL 490
           +T      FGELAL+ +  R+ASVR     +   + +  F ++LL
Sbjct: 68  NTLGAGDYFGELALLDDDRRSASVRTLEKASFLIIYKEEFNKVLL 112


>UniRef50_Q9NQW8 Cluster: Cyclic nucleotide-gated cation channel
           beta 3; n=21; Tetrapoda|Rep: Cyclic nucleotide-gated
           cation channel beta 3 - Homo sapiens (Human)
          Length = 809

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 32/108 (29%), Positives = 55/108 (50%), Gaps = 3/108 (2%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
           LF+  D Q +  +L  +      PG++V ++G+ G   Y+I++G  +V V G     KV+
Sbjct: 524 LFKGCDTQMIYDMLLRLKSVLYLPGDFVCKKGEIGKEMYIIKHG--EVQVLGGPDGTKVL 581

Query: 356 HTYEGSGSFGELALMY---NMPRAASVRAQTAGALWAMDRHTFRRILL 490
            T +    FGE++L+       R A+V A     L  +D+ T + IL+
Sbjct: 582 VTLKAGSVFGEISLLAAGGGNRRTANVVAHGFANLLTLDKKTLQEILV 629


>UniRef50_Q2SDD5 Cluster: CAMP-binding protein-catabolite gene
           activator and regulatory subunit of cAMP-dependent
           protein kinase; n=3; Gammaproteobacteria|Rep:
           CAMP-binding protein-catabolite gene activator and
           regulatory subunit of cAMP-dependent protein kinase -
           Hahella chejuensis (strain KCTC 2396)
          Length = 216

 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 28/88 (31%), Positives = 45/88 (51%)
 Frame = +2

Query: 170 ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEK 349
           I LF   DA+Q+Q +      +  +    VI +GD  D+ Y+I +G   V  + ++  E 
Sbjct: 7   IPLFSGFDAEQLQHLEKHAVFRCFQKNSIVITEGDHSDSLYIIVSGRVRVFCSDENGKEV 66

Query: 350 VVHTYEGSGSFGELALMYNMPRAASVRA 433
            ++  +    FGELAL  +  R+ASV A
Sbjct: 67  TLNDLKAGEYFGELALFDDKERSASVMA 94


>UniRef50_Q08UL3 Cluster: TrkA-N domain family; n=1; Stigmatella
           aurantiaca DW4/3-1|Rep: TrkA-N domain family -
           Stigmatella aurantiaca DW4/3-1
          Length = 377

 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 35/123 (28%), Positives = 58/123 (47%)
 Frame = +2

Query: 122 PKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIE 301
           P   A    L +A+R +     L  + +  V       +   G  + ++GD G+ F+V+ 
Sbjct: 224 PSLAASITPLTQALRKVDFLTPLSDEHLAGVARGAEFLQRPAGAEIFKRGDPGETFFVVL 283

Query: 302 NGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481
            G  +V + GD    +V+      G FGELAL+   PR A+  A +A  L A+ R  FR 
Sbjct: 284 AG--EVKLVGDGG--QVMGMVGPGGFFGELALLTGEPRMATALASSACELAAVGREDFRG 339

Query: 482 ILL 490
           +++
Sbjct: 340 MVM 342


>UniRef50_A0LIE9 Cluster: Cyclic nucleotide-binding protein; n=1;
           Syntrophobacter fumaroxidans MPOB|Rep: Cyclic
           nucleotide-binding protein - Syntrophobacter
           fumaroxidans (strain DSM 10017 / MPOB)
          Length = 308

 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 30/104 (28%), Positives = 48/104 (46%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
           LFR +   ++ ++  +   +      +VIRQGD  D FYVI +G   V    +  +E+ +
Sbjct: 17  LFRDIPKDRLAEIARSAQNRIVPQHGFVIRQGDAADVFYVIASGRVRVTKKNERGMEREL 76

Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
                  +FGE+AL+   PRAA V A          +  F  +L
Sbjct: 77  GFLGPGDNFGEIALLTGEPRAADVVALEETRCMVFSKEQFDALL 120


>UniRef50_Q23EB3 Cluster: Cyclic nucleotide-binding domain
           containing protein; n=1; Tetrahymena thermophila
           SB210|Rep: Cyclic nucleotide-binding domain containing
           protein - Tetrahymena thermophila SB210
          Length = 948

 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 28/106 (26%), Positives = 50/106 (47%), Gaps = 2/106 (1%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL--VTGDDRVEK 349
           +F     Q + +++  M E    PGE +  +GD  D+ Y+I +G  ++L      + +  
Sbjct: 442 IFNCFSQQSINKLVFFMKEIILSPGEVIFSEGDIDDSIYLINSGQIEILRNTAHKNCLSF 501

Query: 350 VVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
            + T   +  FGELA    MPR A+ +      L+ ++R  F  I+
Sbjct: 502 QLKTLSENQIFGELAFFSQMPRTATAKCIKLSMLYKIERKDFIEII 547


>UniRef50_A7SFW1 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 968

 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 26/68 (38%), Positives = 41/68 (60%)
 Frame = +2

Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403
           + E     G  +  QGD+GD++Y+I  G  +V+V G   V + +HT++    FG L+L+ 
Sbjct: 330 VLESCEHKGTVLFNQGDEGDSWYIILKGSVNVVVLGKGIVCQ-LHTWD---DFGRLSLVN 385

Query: 404 NMPRAASV 427
           N PRAAS+
Sbjct: 386 NAPRAASI 393



 Score = 35.9 bits (79), Expect = 0.55
 Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
 Frame = +2

Query: 173 LLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKV 352
           L+F+ +    ++Q+    + +  EPG  + RQ   G N+Y I  G  ++ V+   ++E  
Sbjct: 13  LVFKKVHPHVVRQICFYAYYEDLEPGTVLYRQDAKGLNWYAILTGSVNICVSQTSKIEDA 72

Query: 353 VH-TYEGSGS-FGELALMYNMPRAAS 424
           V     G GS FGE +++   PR A+
Sbjct: 73  VTLCCLGPGSTFGE-SVLDGSPRTAT 97


>UniRef50_UPI0000F1F638 Cluster: PREDICTED: similar to putative
            cNMP-gated potassium channel; n=2; Danio rerio|Rep:
            PREDICTED: similar to putative cNMP-gated potassium
            channel - Danio rerio
          Length = 1716

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 23/79 (29%), Positives = 42/79 (53%)
 Frame = +2

Query: 251  EYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVR 430
            + + ++GD G   Y +E G  +VL   +    KV+        FGE +L+++ PRAA++R
Sbjct: 1099 DVIYKKGDCGSEVYFVEKGEVEVLSNNES---KVLFKLSAGQYFGERSLLFHEPRAATIR 1155

Query: 431  AQTAGALWAMDRHTFRRIL 487
            A T   ++ + + +   IL
Sbjct: 1156 AATNSEMYVLSQKSLHEIL 1174



 Score = 36.7 bits (81), Expect = 0.31
 Identities = 20/65 (30%), Positives = 32/65 (49%)
 Frame = +2

Query: 245 PGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAAS 424
           PG+ + + G+   N Y I++G   V        E  + T      FGE+ L+Y +PR  +
Sbjct: 171 PGQTLAKAGEINQNLYYIKHGHVQVF---SQNPEVEIATLLPGTLFGEVHLLYEIPRNVT 227

Query: 425 VRAQT 439
           +RA T
Sbjct: 228 IRAST 232


>UniRef50_UPI00006CFEF7 Cluster: cation channel family protein; n=1;
            Tetrahymena thermophila SB210|Rep: cation channel family
            protein - Tetrahymena thermophila SB210
          Length = 1392

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 38/175 (21%), Positives = 73/175 (41%), Gaps = 13/175 (7%)
 Frame = +2

Query: 2    EXYFVKKPPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPK-SDAQRARLAEAVRGILL 178
            + Y  +K       +R +S     Y  ++D + E    VF K S+  R  + + + G ++
Sbjct: 605  QRYLNRKNVNISLKSRVRSYLVFLYKEQKDRNQEAEEKVFQKLSNKLRREIVQEINGKIV 664

Query: 179  ------FRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGD-NFYVIENGVFDVLVTGDD 337
                   ++  +  + +++ AM E    P E +  +GD  D + Y I+ G  D+    D 
Sbjct: 665  NSCGIFTKNFSSSTINKIIFAMKECVVSPNEIIFNEGDQDDMSIYFIQGGYVDIFQQNDS 724

Query: 338  RVEK-----VVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
               K     V+     +  FGEL+    +PR A  ++     L+ +    F +I+
Sbjct: 725  DKNKQSNQRVIKRLGQNQIFGELSFFSGLPRKAGAKSVNLTTLYKLAADDFLKIV 779


>UniRef50_Q5NXU3 Cluster: Catabolite gene activator; n=3;
           Rhodocyclaceae|Rep: Catabolite gene activator - Azoarcus
           sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1))
          Length = 223

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 33/111 (29%), Positives = 55/111 (49%), Gaps = 1/111 (0%)
 Frame = +2

Query: 158 AVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDD 337
           A++   LF+ L    +  V      +R   G+ V+  G+  D  Y++  G   V+V+ +D
Sbjct: 11  ALKTFSLFQGLSDDTLATVSRLAMMRRIPRGQSVVHAGERCDFVYLVLTGSLKVVVSDED 70

Query: 338 RVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
             E V+ T  G G  FGE+++    PR+A+V A     L  + ++ FR IL
Sbjct: 71  GRE-VILTILGQGELFGEMSMFGEQPRSATVVAVMPSDLVMIAKNDFRTIL 120


>UniRef50_Q2RK98 Cluster: Transcriptional regulator, Crp/Fnr family;
           n=2; Clostridia|Rep: Transcriptional regulator, Crp/Fnr
           family - Moorella thermoacetica (strain ATCC 39073)
          Length = 225

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 22/92 (23%), Positives = 43/92 (46%)
 Frame = +2

Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
           E +R + +F  L+ +++Q +      +R     Y+  +G+ GD FY ++ G   +    +
Sbjct: 6   EFLRQVPVFAGLEPEELQHIASLALLRRYRKNMYIFMEGEPGDAFYFVKKGAIKLFQVLE 65

Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVR 430
           D  EK++H       F E+ L    P  A+ +
Sbjct: 66  DGREKILHFVREGEIFAEVLLFEGGPYPATAQ 97


>UniRef50_Q935V9 Cluster: Transcriptional regulator with cyclic
           nucleotide-binding domain; n=2; Streptomyces|Rep:
           Transcriptional regulator with cyclic nucleotide-binding
           domain - Streptomyces sp. EC3
          Length = 227

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 25/82 (30%), Positives = 41/82 (50%)
 Frame = +2

Query: 242 EPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAA 421
           E GE ++R+G+ G + Y++ +G + V+   +D  E ++    G    GELA    +PR A
Sbjct: 48  EKGERLLREGEQGSHVYLLLSGWYKVVARTEDDREALMAVRTGGDIVGELACFGTLPRVA 107

Query: 422 SVRAQTAGALWAMDRHTFRRIL 487
           +V A   G    + R  F   L
Sbjct: 108 TVMAAGPGVTRLIGRQEFNDFL 129


>UniRef50_Q7D4Z5 Cluster: Drug transporter; n=19; Mycobacterium|Rep:
           Drug transporter - Mycobacterium tuberculosis
          Length = 1071

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 47/154 (30%), Positives = 67/154 (43%)
 Frame = +2

Query: 23  PPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQ 202
           PPVA    RR    A    P        A A  PK+ ++   L EA+R    F   D QQ
Sbjct: 504 PPVAPLGARRPPRPAPVASPA------AAVAPTPKT-SREVNLLEALR----FARPDTQQ 552

Query: 203 MQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF 382
           ++           + G Y+   GD  D  YV+ +G   VL  GD   ++VV         
Sbjct: 553 IEL----------QAGSYLFHAGDVSDALYVVRSGRLQVLA-GDGAKDEVVAELGRGQVV 601

Query: 383 GELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484
           GEL ++ + PR+ASVRA    +L  + +  F +I
Sbjct: 602 GELGVLLDAPRSASVRAVRDSSLMRVTKAEFAKI 635


>UniRef50_Q05VE2 Cluster: Possible mechanosensitive ion channel;
           n=2; Synechococcus|Rep: Possible mechanosensitive ion
           channel - Synechococcus sp. RS9916
          Length = 494

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 37/134 (27%), Positives = 58/134 (43%), Gaps = 5/134 (3%)
 Frame = +2

Query: 80  PEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYV 259
           P  D   E  PA  P S     +    +    +F  L  QQ+  +      +   PGE V
Sbjct: 303 PVRDIRTEPVPARLPSSAVNPGQKQRLLACTDIFGHLSDQQLGALAANASCQSFAPGETV 362

Query: 260 IRQGDDGDNFYVIENGVFDVL-VTGDDRVEKV----VHTYEGSGSFGELALMYNMPRAAS 424
           +RQG+ GD+ +++ +G  DV   +G +    +    V +   S  FGE+AL     R+AS
Sbjct: 363 VRQGERGDSLFLVVSGSLDVFQASGTNPARSLPGQQVASLHSSDIFGEMALCTGEARSAS 422

Query: 425 VRAQTAGALWAMDR 466
           V       L  ++R
Sbjct: 423 VVCNNECVLIEIER 436


>UniRef50_A6GAV1 Cluster: Protein phosphatase/cyclic
           nucleotide-binding domain protein; n=1; Plesiocystis
           pacifica SIR-1|Rep: Protein phosphatase/cyclic
           nucleotide-binding domain protein - Plesiocystis
           pacifica SIR-1
          Length = 591

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 33/113 (29%), Positives = 56/113 (49%)
 Frame = +2

Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
           + ++ I LF  L+ QQ+ ++++       EP + +  +G  G+  +VI  G  D+     
Sbjct: 269 DTLKQIPLFSELNYQQLVRIMNLTRIVPFEPRDILCYEGQIGEELFVILRGEVDLY---- 324

Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLK 493
            R +    +      FGE+AL+  MPR+A+  A T G L  ++R  F  IL K
Sbjct: 325 -RNDVPFASLPQGAHFGEMALIDAMPRSATAVAATHGKLLMINREDFLEILRK 376


>UniRef50_A0P0J2 Cluster: Putative catabolite gene activator; n=2;
           Stappia aggregata IAM 12614|Rep: Putative catabolite
           gene activator - Stappia aggregata IAM 12614
          Length = 250

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 29/108 (26%), Positives = 49/108 (45%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
           +F +LDAQ  + +    F K+   GE +   G  G +   I  G   V +      E  +
Sbjct: 34  IFDALDAQAREDLARFAFLKKFSAGEVIFTMGTLGQSMMAIAEGTVRVSMFTPSGGEVTL 93

Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSA 499
              +    FGE+AL+    R+ASV+A T   +  ++R  F  +L + +
Sbjct: 94  TDLKTGDVFGEIALLDGQERSASVKALTNCTVVVLERRNFLEVLRRDS 141


>UniRef50_Q45ZY2 Cluster: Hyperpolarization-gated and cyclic
           nucleotide regulated channel; n=1; Strongylocentrotus
           purpuratus|Rep: Hyperpolarization-gated and cyclic
           nucleotide regulated channel - Strongylocentrotus
           purpuratus (Purple sea urchin)
          Length = 638

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 27/80 (33%), Positives = 44/80 (55%)
 Frame = +2

Query: 248 GEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASV 427
           G+ +I+ G  G   Y IE+G  +VLV  DDR   +V+       FGE++L+ +  R AS+
Sbjct: 481 GDVIIKAGSLGGAMYFIEHGTVEVLV--DDR---IVNRLSDGDHFGEISLLIDERRVASI 535

Query: 428 RAQTAGALWAMDRHTFRRIL 487
            A T   ++ + R  F ++L
Sbjct: 536 IAATTCDVFCLSREDFHKVL 555


>UniRef50_Q24DS4 Cluster: Cation channel family protein; n=1;
           Tetrahymena thermophila SB210|Rep: Cation channel family
           protein - Tetrahymena thermophila SB210
          Length = 2194

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 27/113 (23%), Positives = 56/113 (49%), Gaps = 4/113 (3%)
 Frame = +2

Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDN--FYVIENGVFDVL--VT 328
           +  I LF+ +  ++  ++   M E+   PGE +  QGD  DN  +Y+++  V  +    +
Sbjct: 545 LNNIPLFKHI--KEKDKIAKIMEEQLYSPGEMIFHQGDQDDNSLYYIVKGSVSIIFNPTS 602

Query: 329 GDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
             +R  K +H  +    FGE++ +   PR  S +A     ++ ++R  F +++
Sbjct: 603 NQNREAKQIHLIKKKEYFGEISFINGNPRTFSAKAADFCRIYKINRQQFIQVI 655



 Score = 36.3 bits (80), Expect = 0.41
 Identities = 25/114 (21%), Positives = 51/114 (44%), Gaps = 4/114 (3%)
 Frame = +2

Query: 161  VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGD-DGDNFYVIENGVFDVLVTGD- 334
            +  I LF+ +  ++  ++   M E    PGE +  QGD D  + Y I  G   ++   + 
Sbjct: 1632 LNNIPLFKHI--KEKDKIAKIMEEHLYSPGETIFNQGDLDDSSLYYIVKGSVSIIFNPEN 1689

Query: 335  --DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILL 490
              +R  K +   +    FGE++ +   PR  + +      ++ ++R  F + +L
Sbjct: 1690 NPNREAKQIQLVKKKEYFGEISFISGNPRTFTAKTADFCRIYKINRQQFLQTVL 1743


>UniRef50_Q59V20 Cluster: Putative uncharacterized protein; n=1;
           Candida albicans|Rep: Putative uncharacterized protein -
           Candida albicans (Yeast)
          Length = 721

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 32/104 (30%), Positives = 50/104 (48%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
           LF++      +QV   +      P E++I++GD   + Y I  G   V VT  D  E   
Sbjct: 58  LFKNAPTSFHKQVAANLRLIHYRPQEFIIKKGDLSRSMYWILKGT--VSVTSTDGEEVYA 115

Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
              +G   FGE+ ++YN PR A+V A+T   L  +   +  R+L
Sbjct: 116 ELNQGE-FFGEIGILYNRPRTATVIAKTRILLGVLTAESLNRVL 158



 Score = 33.1 bits (72), Expect = 3.9
 Identities = 26/111 (23%), Positives = 53/111 (47%), Gaps = 2/111 (1%)
 Frame = +2

Query: 113 AVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDD-GDNF 289
           A+  K + +   +   +  + LF+ L    + ++  ++      P EY++R+GD  GD +
Sbjct: 177 AMQDKKNKEPLSIQSFITNLPLFQFLPPDIIHKLALSVEPLVFSPFEYILRKGDTCGDIY 236

Query: 290 YVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQT 439
           ++IE    +V V   + V ++      SGS FGE++ +  +     +R  T
Sbjct: 237 FIIEG---EVEVLNQEGVIEIPLARLSSGSYFGEMSFLNYLQNKPRIRTAT 284


>UniRef50_Q8XR93 Cluster: Probable transcription regulator protein;
           n=6; Ralstonia|Rep: Probable transcription regulator
           protein - Ralstonia solanacearum (Pseudomonas
           solanacearum)
          Length = 225

 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 25/86 (29%), Positives = 40/86 (46%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
           LF  LDA+ +  +     + R    ++V  +GD  D FYV+  G   +++ G     KV+
Sbjct: 16  LFEGLDAEDLATLARDSHQIRLARHDFVFHRGDCADGFYVVAVGTIKLVLPGAHGHNKVI 75

Query: 356 HTYEGSGSFGELALMYNMPRAASVRA 433
             +     FGE  +  N P AA  +A
Sbjct: 76  EFFGPGEYFGEPFMFLNQPHAADAQA 101


>UniRef50_Q2K3Q8 Cluster: Probable cation transporter protein; n=2;
           Rhizobium|Rep: Probable cation transporter protein -
           Rhizobium etli (strain CFN 42 / ATCC 51251)
          Length = 581

 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 33/115 (28%), Positives = 53/115 (46%), Gaps = 1/115 (0%)
 Frame = +2

Query: 146 RLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDV-L 322
           ++ + +    LF  +     +++L     K + PGE VIR+GD GD+ Y I +G  +V L
Sbjct: 440 KMQQLIETFPLFSQVGEDAQEELLLLFKAKSAPPGERVIRRGDRGDSMYFISSGAVEVRL 499

Query: 323 VTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
            +G  R+E           FGE+AL+    R A V A        ++R  F   +
Sbjct: 500 ASGAIRLEP-------GAFFGEMALLSGGRRTADVIAVDFCQFEVLERRDFNMFM 547


>UniRef50_Q1NMR4 Cluster: Cyclic nucleotide-binding; n=2; delta
           proteobacterium MLMS-1|Rep: Cyclic nucleotide-binding -
           delta proteobacterium MLMS-1
          Length = 358

 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 26/66 (39%), Positives = 36/66 (54%), Gaps = 1/66 (1%)
 Frame = +2

Query: 245 PGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF-GELALMYNMPRAA 421
           PGE +  +GD G + Y IE G  ++ V  D R   V++T  G+G   G L  +   PR A
Sbjct: 13  PGELLFNKGDPGGDLYFIEQGSLEIFVYQDGR--PVIYTEMGAGEIVGVLTCLTGEPRMA 70

Query: 422 SVRAQT 439
           S RA+T
Sbjct: 71  SARAKT 76


>UniRef50_Q0LJ13 Cluster: Cyclic nucleotide-binding; n=2;
           Chloroflexi (class)|Rep: Cyclic nucleotide-binding -
           Herpetosiphon aurantiacus ATCC 23779
          Length = 166

 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 25/96 (26%), Positives = 51/96 (53%), Gaps = 5/96 (5%)
 Frame = +2

Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV----- 325
           +R + +F  L+  ++ Q+       +++ G+ + R+  DGD+ YV+ +G  ++ V     
Sbjct: 9   LRRVDIFAGLNDLELSQIAQLCKVAKAKKGQIIFREDSDGDDLYVVHDGAVEIQVQTRGS 68

Query: 326 TGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRA 433
            G  R+  +   YEG  +FGE+A++    R+A+  A
Sbjct: 69  DGQHRLSTINTAYEGQ-AFGEIAMLGGGSRSATAVA 103


>UniRef50_A4XWI5 Cluster: Cyclic nucleotide-binding protein; n=2;
           Pseudomonas|Rep: Cyclic nucleotide-binding protein -
           Pseudomonas mendocina ymp
          Length = 369

 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 32/105 (30%), Positives = 52/105 (49%), Gaps = 1/105 (0%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV-TGDDRVEKV 352
           LF  +    +Q +L  +       G  V+ +G  GD  + +E+G  +V+   G DR  +V
Sbjct: 144 LFAKVPPANVQSMLGRLQRIEVAAGSQVLEEGAAGDCCFFLESGRAEVIRRAGSDR--QV 201

Query: 353 VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
           +   E    FGE AL+ + PR A+V    AG++  +DR  F  +L
Sbjct: 202 LAELEVGACFGEEALLADRPRNATVTMVEAGSVLRLDRQDFFALL 246


>UniRef50_A1ZHX6 Cluster: Serine/threonine protein kinases; n=1;
           Microscilla marina ATCC 23134|Rep: Serine/threonine
           protein kinases - Microscilla marina ATCC 23134
          Length = 455

 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 28/123 (22%), Positives = 52/123 (42%)
 Frame = +2

Query: 122 PKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIE 301
           P  D   A     ++ + +F   D   +  +   + E+       +I++GD G++ Y+I 
Sbjct: 4   PVKDIDLAEKVAILKTVKVFAETDQDVLVNIAKVLTEEHHPKDSLIIKKGDPGESMYIIV 63

Query: 302 NGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481
           +G   V   G   V            FGE AL+   PR+A V       LW +++  F +
Sbjct: 64  DGAVRVHDGGYTFV-----VLRNRNVFGEYALLDTKPRSADVTTLRRTRLWKLNQDVFYK 118

Query: 482 ILL 490
           +++
Sbjct: 119 VMM 121


>UniRef50_A0L6N5 Cluster: Cyclic nucleotide-binding; n=1;
           Magnetococcus sp. MC-1|Rep: Cyclic nucleotide-binding -
           Magnetococcus sp. (strain MC-1)
          Length = 729

 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 27/106 (25%), Positives = 52/106 (49%), Gaps = 1/106 (0%)
 Frame = +2

Query: 173 LLFRSLDAQQMQ-QVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEK 349
           LL R + + +M  ++L  + E   + G+ +  QG+  D  Y+IE+G   +  +  D   K
Sbjct: 590 LLTRIMGSTEMATRILPYLKELSLKSGDILFEQGEVTDGLYIIESGKIAIYFSHPDGWTK 649

Query: 350 VVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
            V   E     GE+ L + +PR+A+   + +G +       ++R+L
Sbjct: 650 QVRILEQGTLVGEMGLYHTLPRSAAAIVEESGIVHHFSHANYQRLL 695


>UniRef50_Q554K9 Cluster: CGMP-stimulated cGMP phosphodiesterase;
           n=2; Dictyostelium discoideum|Rep: CGMP-stimulated cGMP
           phosphodiesterase - Dictyostelium discoideum AX4
          Length = 867

 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 32/127 (25%), Positives = 63/127 (49%)
 Frame = +2

Query: 116 VFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYV 295
           V   S ++   + + V  + +FRS+   Q  ++L    +++   G  +I +  + D FYV
Sbjct: 587 VMKSSHSEAVDILKLVESVDIFRSIPLTQACEILQTATKRKYSQGSVIIARDTEPDAFYV 646

Query: 296 IENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTF 475
           + +GV  V + G+ +   +V  Y     FGE++L+    R+A+V+A T   + + ++  F
Sbjct: 647 VASGVVCVNI-GELKKNLIVGDY-----FGEMSLVMGGLRSANVQAVTDVEVLSFNKEDF 700

Query: 476 RRILLKS 496
             I   S
Sbjct: 701 LSITRNS 707


>UniRef50_A0CLY8 Cluster: Chromosome undetermined scaffold_21, whole
           genome shotgun sequence; n=3; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_21,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 513

 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 28/96 (29%), Positives = 47/96 (48%), Gaps = 1/96 (1%)
 Frame = +2

Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVE-KVVHTYEGSGSFGELALM 400
           M+ ++ +  E V      G  FY+I  G   VLV   ++ + + V       SFGELAL+
Sbjct: 57  MYCEKFKASEIVFYVDSVGTKFYIILEGSVTVLVRKPNQSDMEAVRILNKGESFGELALL 116

Query: 401 YNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKK 508
           +  PR A+++  T      +D+  F+ IL +   K+
Sbjct: 117 HKQPRLATIQCNTDCTFAVLDKQQFKHILQEEQQKQ 152


>UniRef50_O95398 Cluster: Rap guanine nucleotide exchange factor 3;
           n=33; Euteleostomi|Rep: Rap guanine nucleotide exchange
           factor 3 - Homo sapiens (Human)
          Length = 881

 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = +2

Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403
           +FE  S+ G  +  QGD G ++Y+I  G  +V+  G    + +V T      FG+LAL+ 
Sbjct: 220 LFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHG----KGLVTTLHEGDDFGQLALVN 275

Query: 404 NMPRAASVRAQTAGA-LWAMDRHTFRRIL 487
           + PRAA++  +        +D+  F RI+
Sbjct: 276 DAPRAATIILREDNCHFLRVDKQDFNRII 304


>UniRef50_Q7V424 Cluster: Possible mechanosensitive ion channel;
           n=1; Prochlorococcus marinus str. MIT 9313|Rep: Possible
           mechanosensitive ion channel - Prochlorococcus marinus
           (strain MIT 9313)
          Length = 496

 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 31/105 (29%), Positives = 50/105 (47%), Gaps = 1/105 (0%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
           LF  L   Q+  +  +    R   GE +IRQG+ GD  Y +  G  +V  T + + +K+ 
Sbjct: 339 LFTDLSQAQLDALAPSTRCVRFAKGETIIRQGESGDCLYQMITGTVEVSQT-NSQGQKIT 397

Query: 356 HTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
               G    FGE+AL    PR ++VRA     L  ++R   + ++
Sbjct: 398 FQKLGQHEIFGEMALCTKQPRNSTVRALEESVLLEVERRDLQPLI 442


>UniRef50_Q9X7J4 Cluster: DnrD protein; n=9; Pseudomonas|Rep: DnrD
           protein - Pseudomonas stutzeri (Pseudomonas
           perfectomarina)
          Length = 227

 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 28/112 (25%), Positives = 51/112 (45%), Gaps = 1/112 (0%)
 Frame = +2

Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
           + +R   LF  L+ +QM+++L+A      + G+ +  QG+   NFY + +G   V     
Sbjct: 9   QILRSHHLFEPLNEEQMEELLNASQLLNLDKGDNLFHQGEPAHNFYFVISGAVKVYRLTP 68

Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPR-AASVRAQTAGALWAMDRHTFRRIL 487
           D  EKV        +F E  ++ + P   AS +A     ++      + R+L
Sbjct: 69  DGQEKVFEVIGNRQTFAEAMMLMDTPNYVASAQAVCPSQVYRFSNAAYMRLL 120


>UniRef50_Q1YDI6 Cluster: Possible cAMP-dependent regulatory
           protein; n=1; Aurantimonas sp. SI85-9A1|Rep: Possible
           cAMP-dependent regulatory protein - Aurantimonas sp.
           SI85-9A1
          Length = 158

 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 28/111 (25%), Positives = 57/111 (51%)
 Frame = +2

Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
           + +R + +F  ++  +++ +           G+ + RQG+ GD+ YVI  G  DV +  +
Sbjct: 9   DLLRSVPIFAGMEPSRLKLIAFTSDSIAYRQGQVMCRQGERGDSAYVIVAGKADVSIETE 68

Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
           D  + VV T       GE+A++ + PR A+V A++  +   + +  F ++L
Sbjct: 69  DG-DFVVATLGPGDVVGEIAILCDTPRTATVTAKSDVSALRVRKECFLQLL 118


>UniRef50_A7SKJ9 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 1023

 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 26/91 (28%), Positives = 45/91 (49%)
 Frame = +2

Query: 242 EPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAA 421
           +PG+Y++  GD G   Y I  G  ++L       + V+ T      FGE+ L+Y   R A
Sbjct: 45  KPGDYIVYAGDMGREMYCIRRGQVNILCE-----DNVIGTLGPGSFFGEIGLIYGESRFA 99

Query: 422 SVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
           +V+A+T   +  + +H    +L +    KR+
Sbjct: 100 TVQAKTYCQILMLTKHDLDEVLEEFPIIKRQ 130



 Score = 34.7 bits (76), Expect = 1.3
 Identities = 21/81 (25%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
 Frame = +2

Query: 248  GEYVIRQGDDGDNFYVIENGVFDVLVTGD-DRVEKVVHTYEGSGSFGELALMYNMPRAAS 424
            GEY+IR+GD G    +++ G   ++ + D +++E++V     +  + +  L+   P   S
Sbjct: 920  GEYIIRKGDIGQQLIILKRGTAAIVKSEDPEKLEEMV----VNSFYSQRYLLLTGPYLES 975

Query: 425  VRAQTAGALWAMDRHTFRRIL 487
            VRA T   ++ +D+     +L
Sbjct: 976  VRAITNVDVFLLDKKDLYEVL 996


>UniRef50_P34578 Cluster: Uncharacterized protein T20G5.5; n=2;
           Caenorhabditis|Rep: Uncharacterized protein T20G5.5 -
           Caenorhabditis elegans
          Length = 1234

 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 28/87 (32%), Positives = 47/87 (54%), Gaps = 1/87 (1%)
 Frame = +2

Query: 230 EKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNM 409
           E+    G  V RQG+ G  +Y++  G  +V V G     K+V        FG+LAL+ ++
Sbjct: 590 EQYVHAGSVVFRQGEIGVYWYIVLKGAVEVNVNG-----KIVCLLREGDDFGKLALVNDL 644

Query: 410 PRAASVRAQTAGALW-AMDRHTFRRIL 487
           PRAA++      +++  +D+H F +IL
Sbjct: 645 PRAATIVTYEDDSMFLVVDKHHFNQIL 671


>UniRef50_UPI000065E24B Cluster: Rap guanine nucleotide exchange
           factor 3 (cAMP-regulated guanine nucleotide exchange
           factor I) (cAMP-GEFI) (Exchange factor directly
           activated by cAMP 1) (Epac 1) (Rap1
           guanine-nucleotide-exchange factor directly activated by
           cAMP).; n=1; Takifugu rubripes|Rep: Rap guanine
           nucleotide exchange factor 3 (cAMP-regulated guanine
           nucleotide exchange factor I) (cAMP-GEFI) (Exchange
           factor directly activated by cAMP 1) (Epac 1) (Rap1
           guanine-nucleotide-exchange factor directly activated by
           cAMP). - Takifugu rubripes
          Length = 908

 Score = 46.4 bits (105), Expect = 4e-04
 Identities = 29/89 (32%), Positives = 48/89 (53%), Gaps = 1/89 (1%)
 Frame = +2

Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403
           +FE  ++ G  +  QGD G ++Y+I  G  +V+  G   V  +   +EG   FG+LAL+ 
Sbjct: 172 VFESHAKAGTVLFSQGDKGTSWYIIWKGSVNVITHGKGLVTTL---HEGE-DFGQLALLN 227

Query: 404 NMPRAASVRAQTAGA-LWAMDRHTFRRIL 487
           + PRAA++  +        +D+  F RIL
Sbjct: 228 DAPRAATIILREDNCHFLRVDKQDFIRIL 256


>UniRef50_Q92SD2 Cluster: PUTATIVE TRANSCRIPTION REGULATOR PROTEIN;
           n=2; Sinorhizobium|Rep: PUTATIVE TRANSCRIPTION REGULATOR
           PROTEIN - Rhizobium meliloti (Sinorhizobium meliloti)
          Length = 234

 Score = 46.4 bits (105), Expect = 4e-04
 Identities = 24/108 (22%), Positives = 50/108 (46%)
 Frame = +2

Query: 164 RGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRV 343
           R   +F   D++ + ++      ++   G  + ++GD GD   V+ +G   + +      
Sbjct: 12  RSFPIFEEFDSETLCELSGIASYRKWSAGTVIFQRGDQGDYMIVVVSGRIKLSLFTPQGR 71

Query: 344 EKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
           E ++  +E    FGE+AL+   PR+A   A TA   + + +  F  ++
Sbjct: 72  ELMLRQHEAGALFGEMALLDGQPRSADATAVTAAEGYVIGKKDFLALI 119


>UniRef50_Q30Y06 Cluster: Transcriptional regulator, Crp/Fnr family;
           n=3; Desulfovibrio|Rep: Transcriptional regulator,
           Crp/Fnr family - Desulfovibrio desulfuricans (strain
           G20)
          Length = 248

 Score = 46.4 bits (105), Expect = 4e-04
 Identities = 21/79 (26%), Positives = 39/79 (49%)
 Frame = +2

Query: 170 ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEK 349
           I LF  L AQQ++ +     ++  + G+ +  +G   +  Y++ +G   +  T  D  E 
Sbjct: 31  IPLFSGLSAQQLESMASIAVDRPVDKGQIIFVEGTRAEGLYIVLDGRVKIFKTAPDGREA 90

Query: 350 VVHTYEGSGSFGELALMYN 406
           V+H +     FGE+A+  N
Sbjct: 91  VMHVFGAGEPFGEVAVFQN 109


>UniRef50_Q7CWQ8 Cluster: AGR_C_4670p; n=6; Rhizobiaceae|Rep:
           AGR_C_4670p - Agrobacterium tumefaciens (strain C58 /
           ATCC 33970)
          Length = 162

 Score = 46.4 bits (105), Expect = 4e-04
 Identities = 27/95 (28%), Positives = 47/95 (49%)
 Frame = +2

Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
           + ++ +  F  ++  +++ +  A        G+ + RQGD GD  YV+  G  DVLV   
Sbjct: 19  QMLKRVPFFSEMEPSKLKLLAFASDRVSYHAGDTLFRQGDVGDAAYVLLTGKVDVLVDSP 78

Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQT 439
               KV     G+   GE+A++ +  R A++RA T
Sbjct: 79  SGTLKVAE-MTGNAIVGEIAILCDSVRTATIRAST 112


>UniRef50_Q236Y9 Cluster: Cyclic nucleotide-binding domain
           containing protein; n=1; Tetrahymena thermophila
           SB210|Rep: Cyclic nucleotide-binding domain containing
           protein - Tetrahymena thermophila SB210
          Length = 983

 Score = 46.4 bits (105), Expect = 4e-04
 Identities = 27/102 (26%), Positives = 49/102 (48%), Gaps = 1/102 (0%)
 Frame = +2

Query: 206 QQVLDAMFEKRSEPGEYVIRQGDDGD-NFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF 382
           +++   M E    PGEY+ ++ D  D + Y+I  G  D++ T + R E ++ T +    F
Sbjct: 321 KEIAIIMEEVIFSPGEYIYQKDDVDDCSLYLIVKGQVDIVFTSEKRGESIIQTLDKLKYF 380

Query: 383 GELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKK 508
           GE + +    R  S +A T   ++ + R+ F   +    F K
Sbjct: 381 GEQSFISGFQRELSAKAATFCRVYKIPRNKFLETIKLYDFDK 422


>UniRef50_A0CY63 Cluster: Chromosome undetermined scaffold_301,
           whole genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_301,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 785

 Score = 46.4 bits (105), Expect = 4e-04
 Identities = 28/57 (49%), Positives = 34/57 (59%), Gaps = 5/57 (8%)
 Frame = +2

Query: 245 PGEYVIRQGDDGDNFYVIENGVFDVLV----TGDDRV-EKVVHTYEGSGSFGELALM 400
           PGEYV  QGD GDN +VI +G  DV +    T D  V E+VV +      FGELA+M
Sbjct: 297 PGEYVFHQGDFGDNLFVILSGSVDVKIEKKFTQDGPVIEQVVSSLYDGQHFGELAMM 353


>UniRef50_P0A642 Cluster: Uncharacterized NTE family protein
           Rv2565/MT2641; n=7; Mycobacterium tuberculosis
           complex|Rep: Uncharacterized NTE family protein
           Rv2565/MT2641 - Mycobacterium tuberculosis
          Length = 583

 Score = 46.4 bits (105), Expect = 4e-04
 Identities = 29/122 (23%), Positives = 60/122 (49%)
 Frame = +2

Query: 122 PKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIE 301
           PK     AR A  +R + +   +D +Q++++   +  +     +++   G+  D+ Y+++
Sbjct: 8   PKRRGTDARTA--LRNVPILADIDDEQLERLATTVERRHVPANQWLFHAGEPADSIYIVD 65

Query: 302 NGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481
           +G F V V  +  V   + + +   S G+L ++    R+A VRA   G +W +   TF  
Sbjct: 66  SGRF-VAVAPEGHVFAEMASGD---SIGDLGVIAGAARSAGVRALRDGVVWRIAAETFTD 121

Query: 482 IL 487
           +L
Sbjct: 122 ML 123


>UniRef50_UPI00015BC926 Cluster: UPI00015BC926 related cluster; n=1;
           unknown|Rep: UPI00015BC926 UniRef100 entry - unknown
          Length = 219

 Score = 46.0 bits (104), Expect = 5e-04
 Identities = 25/114 (21%), Positives = 53/114 (46%)
 Frame = +2

Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
           + +R + LF  +  + ++++      +  + GE V  +GD  +N Y++ +G+  V    +
Sbjct: 6   DLLRNVYLFSKVSDENLKKLKSISNIRNFKKGEIVFHEGDKPENIYILLDGLVKVYKLTN 65

Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKS 496
              E V+  ++     GE+A   N+   A+    T G +  +D   F+R  + S
Sbjct: 66  KGTEVVITQFKPVSIIGEMANFENISYPATAEFITEGQVLQIDFEAFKREFMTS 119


>UniRef50_UPI00006CE543 Cluster: cyclic nucleotide-binding domain
           containing protein; n=1; Tetrahymena thermophila
           SB210|Rep: cyclic nucleotide-binding domain containing
           protein - Tetrahymena thermophila SB210
          Length = 637

 Score = 46.0 bits (104), Expect = 5e-04
 Identities = 29/111 (26%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
 Frame = +2

Query: 191 DAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVE-----KVV 355
           D  +   +   ++ K+ E  ++V +QG+ GD FY+I  G   + +      +     K V
Sbjct: 210 DIPEFIDICRNLYIKQYEKKQFVFKQGEYGDAFYIILYGSVTIYIDEPTEYKSFMQLKEV 269

Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKK 508
              E   +FGE+AL+Y+  R A+V A     L  ++++ F+  + +  F K
Sbjct: 270 AKLEQGDTFGEIALIYDSQRTATVIANEKTYLVVLEKNIFQSYIKQIDFFK 320


>UniRef50_UPI00006CB774 Cluster: cyclic nucleotide-binding domain
           containing protein; n=1; Tetrahymena thermophila
           SB210|Rep: cyclic nucleotide-binding domain containing
           protein - Tetrahymena thermophila SB210
          Length = 873

 Score = 46.0 bits (104), Expect = 5e-04
 Identities = 29/103 (28%), Positives = 52/103 (50%), Gaps = 3/103 (2%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDD-RVEKV 352
           LF  L  +  + ++DA+  +  E G+ + ++GD G  F++I++G   +    ++ +++KV
Sbjct: 582 LFEDLSIKHAKHLIDAVQVEEYEKGDIIFKEGDIGHKFFIIQSGAVRIYTDNENIQIDKV 641

Query: 353 --VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTF 475
             V  Y G GS     L  +  R A   A T   L  ++RH F
Sbjct: 642 FKVGDYFGEGSL----LDSSNKRIAQAEAITDCQLLTLERHDF 680


>UniRef50_Q2W0I8 Cluster: Kef-type K+ transport systems, predicted
           NAD-binding component; n=3; Magnetospirillum|Rep:
           Kef-type K+ transport systems, predicted NAD-binding
           component - Magnetospirillum magneticum (strain AMB-1 /
           ATCC 700264)
          Length = 394

 Score = 46.0 bits (104), Expect = 5e-04
 Identities = 30/109 (27%), Positives = 52/109 (47%)
 Frame = +2

Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
           V  +  F+ L A Q+ ++   +   R+  GE ++R+GD G+  Y I +G  +V       
Sbjct: 254 VAKVPFFQRLQASQIAEIAGLLKLARAIKGEVLMREGDTGECMYFIVSGQVEVKGRAGTF 313

Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
           + K          FGE+AL+   PR A+V+A +   L  +D   F + +
Sbjct: 314 ILK------NGDFFGEIALIERCPRTATVKAVSRCQLLILDARDFHKFV 356


>UniRef50_Q0VS63 Cluster: Cyclic nucleotide-binding protein; n=1;
           Alcanivorax borkumensis SK2|Rep: Cyclic
           nucleotide-binding protein - Alcanivorax borkumensis
           (strain SK2 / ATCC 700651 / DSM 11573)
          Length = 153

 Score = 46.0 bits (104), Expect = 5e-04
 Identities = 28/107 (26%), Positives = 48/107 (44%)
 Frame = +2

Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
           LF  L   ++  +   +F  R   G+ V R+GD  D    +  G  D++   +   E V+
Sbjct: 13  LFAGLSEDELAILEKLVFVNRVPVGDVVCREGDRSDFVCFVVRGCLDIVKNNEGGGEVVI 72

Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKS 496
                    GE+AL+ + PR+A+VRA     L  + R    ++  +S
Sbjct: 73  AHLRPGDCMGEMALVDHEPRSATVRAAEDATLIVLTRKGIEQLRKRS 119


>UniRef50_A0E9X9 Cluster: Chromosome undetermined scaffold_85, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_85,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 340

 Score = 46.0 bits (104), Expect = 5e-04
 Identities = 26/106 (24%), Positives = 56/106 (52%), Gaps = 1/106 (0%)
 Frame = +2

Query: 182 RSLDAQQMQQVLDAMFE-KRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVH 358
           R +  + + QV+ +  + ++    + + + GD G+ FYVI  G+  V V  +D++  +  
Sbjct: 11  RIIVGEDLYQVIKSKMQIEQYSVNDVLTKIGDKGNKFYVILQGLVGVFVRNEDQLTMINV 70

Query: 359 TYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKS 496
             EG G  GEL++M N  R A++   T   +  +  + ++R ++++
Sbjct: 71  CREGEG-MGELSIMSNKSRMATLVCLTDCVIATLTAYQYKRYVMQN 115


>UniRef50_A0CUC4 Cluster: Chromosome undetermined scaffold_28, whole
           genome shotgun sequence; n=4; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_28,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 470

 Score = 46.0 bits (104), Expect = 5e-04
 Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 13/101 (12%)
 Frame = +2

Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR-------------VEKVVHTY 364
           ++ K  E  +Y+ +QGD GD FYVI NG   V +                  ++K +   
Sbjct: 74  LYLKTYEKRQYIFKQGDQGDAFYVILNGSVKVYIDEPTEFKNFMQLVRVVCFIQKEIAQL 133

Query: 365 EGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
               +FGE++L+YN  R A+V A     L  +++  F+  +
Sbjct: 134 GKGDAFGEISLLYNSKRTATVIANERSDLIVLEKDAFQEYM 174


>UniRef50_Q2WA28 Cluster: CheY-like receiver; n=3;
           Magnetospirillum|Rep: CheY-like receiver -
           Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
          Length = 328

 Score = 45.6 bits (103), Expect = 7e-04
 Identities = 27/68 (39%), Positives = 39/68 (57%), Gaps = 1/68 (1%)
 Frame = +2

Query: 233 KRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEG-SGSFGELALMYNM 409
           K+   G+ V  +GD GD  YV+E+G   +  T +   +KV+    G +G FGE+AL+ N 
Sbjct: 206 KKFHAGQIVFSEGDAGDMAYVVESGKVSIFKTVNG--QKVILGQIGPNGVFGEMALIDNE 263

Query: 410 PRAASVRA 433
           PR AS  A
Sbjct: 264 PRMASAMA 271


>UniRef50_Q2G4A2 Cluster: Cyclic nucleotide-binding domain (CNMP-BD)
           protein; n=1; Novosphingobium aromaticivorans DSM
           12444|Rep: Cyclic nucleotide-binding domain (CNMP-BD)
           protein - Novosphingobium aromaticivorans (strain DSM
           12444)
          Length = 321

 Score = 45.6 bits (103), Expect = 7e-04
 Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 2/82 (2%)
 Frame = +2

Query: 248 GEYVIRQGDDGDNFYVIENGVFDV--LVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAA 421
           GE + RQGD     Y++  G+ ++   + GD+    V+   E     GE AL+ + PR+A
Sbjct: 34  GETLFRQGDPPSALYLVGEGLLEIETRLPGDEAA--VISRIEPGQMVGEFALLDDGPRSA 91

Query: 422 SVRAQTAGALWAMDRHTFRRIL 487
           +VRA  A A + + R  FR +L
Sbjct: 92  NVRAVDASAGFVIARDRFRALL 113


>UniRef50_Q1GTY7 Cluster: Transcriptional regulator, Crp/Fnr family;
           n=3; Sphingomonadaceae|Rep: Transcriptional regulator,
           Crp/Fnr family - Sphingopyxis alaskensis (Sphingomonas
           alaskensis)
          Length = 227

 Score = 45.6 bits (103), Expect = 7e-04
 Identities = 33/113 (29%), Positives = 52/113 (46%), Gaps = 1/113 (0%)
 Frame = +2

Query: 143 ARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDV- 319
           ARLAE      +F  L  +   ++     +     G+ ++ QGD GD   ++  G   V 
Sbjct: 4   ARLAELQSPDSIFSGLSVEDWAEITRRAVQVNFAKGKELLVQGDPGDMMLILTEGTARVS 63

Query: 320 LVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFR 478
           ++T   R E V+   E     GE+AL+    R ASV A +AG+   + R+  R
Sbjct: 64  MLTAGGR-EIVLAYAEPGAVLGEIALLDGGERTASVTATSAGSALQLGRNALR 115


>UniRef50_Q0EYN2 Cluster: Possible mechanosensitive ion channel;
           n=1; Mariprofundus ferrooxydans PV-1|Rep: Possible
           mechanosensitive ion channel - Mariprofundus
           ferrooxydans PV-1
          Length = 156

 Score = 45.6 bits (103), Expect = 7e-04
 Identities = 27/100 (27%), Positives = 53/100 (53%)
 Frame = +2

Query: 197 QQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSG 376
           QQ++ V+ A+  K+   G+ ++++G+ G   Y++ +G  D+    D +V+++    EGS 
Sbjct: 23  QQLEGVVRAVAIKK---GDTIVKEGEKGGILYLVRSGCVDIFQDLDGQVQRLAGLGEGS- 78

Query: 377 SFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKS 496
             GE+  +      A+V A     ++ MDR  F R++  S
Sbjct: 79  MIGEVTFLSGELATATVVAAEDSIVYTMDRAGFARLMQTS 118


>UniRef50_A7BRS9 Cluster: Transcriptional Regulator, Crp/Fnr family;
           n=1; Beggiatoa sp. PS|Rep: Transcriptional Regulator,
           Crp/Fnr family - Beggiatoa sp. PS
          Length = 248

 Score = 45.6 bits (103), Expect = 7e-04
 Identities = 26/88 (29%), Positives = 45/88 (51%)
 Frame = +2

Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
           + ++ I LF  L+ QQ  Q+   M   R E GEY+ + G   ++F++++ G   +L    
Sbjct: 14  QELQKIYLFSGLNDQQFTQIKQGMRPIRLEDGEYLFKHGQRAEHFFMLKEGYIKLLRLSL 73

Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRA 418
           +  EKV        +F E A+M+ MP +
Sbjct: 74  EGAEKVFEVVSPGQTFAE-AIMF-MPNS 99


>UniRef50_A6G7H5 Cluster: Serine/threonine-protein kinase; n=2;
           Plesiocystis pacifica SIR-1|Rep:
           Serine/threonine-protein kinase - Plesiocystis pacifica
           SIR-1
          Length = 547

 Score = 45.6 bits (103), Expect = 7e-04
 Identities = 25/65 (38%), Positives = 38/65 (58%)
 Frame = +2

Query: 245 PGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAAS 424
           PG+++IR+ + GD  Y+I  G  +V  + D R E +   + G   FGE A++ + PR AS
Sbjct: 347 PGDWIIREDEVGDAAYIILTGSCEVFKSIDGRWESLRKLHAGE-VFGETAILASTPRTAS 405

Query: 425 VRAQT 439
           V A T
Sbjct: 406 VVALT 410


>UniRef50_A5UZM8 Cluster: Cyclic nucleotide-binding protein; n=3;
           Chloroflexaceae|Rep: Cyclic nucleotide-binding protein -
           Roseiflexus sp. RS-1
          Length = 167

 Score = 45.6 bits (103), Expect = 7e-04
 Identities = 28/98 (28%), Positives = 45/98 (45%), Gaps = 4/98 (4%)
 Frame = +2

Query: 146 RLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV 325
           R+ E +R + +F  L   ++ QV       R+   + V  +GD GD  Y++  G   V++
Sbjct: 4   RVLENLRKVEIFAGLSDDELMQVAGVCRAIRTPASQTVFNEGDTGDELYIVHEGTVRVMI 63

Query: 326 T---GDDRV-EKVVHTYEGSGSFGELALMYNMPRAASV 427
           T    D  V    ++T      FGE AL+    R A+V
Sbjct: 64  TTRLSDGTVAPSTINTLYPGQCFGEQALLGGAARTATV 101


>UniRef50_Q23DN4 Cluster: Cyclic nucleotide-binding domain
           containing protein; n=1; Tetrahymena thermophila
           SB210|Rep: Cyclic nucleotide-binding domain containing
           protein - Tetrahymena thermophila SB210
          Length = 809

 Score = 45.6 bits (103), Expect = 7e-04
 Identities = 33/103 (32%), Positives = 54/103 (52%), Gaps = 1/103 (0%)
 Frame = +2

Query: 170 ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEK 349
           I +F S+  +  + +L +  E+  +PGEYVIRQG  G  FY + +G+  +    DD   +
Sbjct: 544 IEIFESISIKNFRDLLQSAKEEYYDPGEYVIRQGTIGTKFYFVMSGIVCIF---DD--AR 598

Query: 350 VVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTF 475
            +  +  +GS FGE AL  +  R    RA T   L ++++  F
Sbjct: 599 SLSRFCPTGSYFGETALKVDSTR----RAVTPCELLSLEKQDF 637


>UniRef50_A7SKJ5 Cluster: Predicted protein; n=2; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 2425

 Score = 45.6 bits (103), Expect = 7e-04
 Identities = 22/63 (34%), Positives = 35/63 (55%)
 Frame = +2

Query: 251  EYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVR 430
            EY++RQG+ G   Y I+ G  +VL    DR    +        FGE+++++N PR  S+R
Sbjct: 1760 EYIVRQGEIGHEMYFIQKGDVEVL----DRDGNALAVLGPGSFFGEVSVLFNTPRTTSIR 1815

Query: 431  AQT 439
             +T
Sbjct: 1816 TRT 1818



 Score = 45.2 bits (102), Expect = 9e-04
 Identities = 23/81 (28%), Positives = 47/81 (58%)
 Frame = +2

Query: 245 PGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAAS 424
           P + ++++G+ G +   I  G  ++    DD + + +   EG   FGE++L+YNM RA++
Sbjct: 743 PSQMIVKKGETGQSICYIHKGKAEIY--DDDDITQSIVLEEGY-IFGEVSLVYNMLRASN 799

Query: 425 VRAQTAGALWAMDRHTFRRIL 487
           VRA +   ++ ++R    ++L
Sbjct: 800 VRALSPCVVFILNRDDMNKVL 820



 Score = 42.7 bits (96), Expect = 0.005
 Identities = 29/121 (23%), Positives = 54/121 (44%)
 Frame = +2

Query: 125  KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 304
            + D       + +R + LF   D   ++Q+         +PG+Y++  GD G   Y I  
Sbjct: 1204 QQDVCEQESTDILREVPLFIECDENFIKQLSLCTTSYIFKPGDYIVYAGDMGREMYCIRR 1263

Query: 305  GVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484
            G  ++L   D+  ++VV T      FGE+ L+    R  +V+ +T      + +H   ++
Sbjct: 1264 GQVNIL--NDE--DEVVGTLGPGSFFGEIGLVCGESRVYTVQCKTYCQTLMLTKHDMDKV 1319

Query: 485  L 487
            L
Sbjct: 1320 L 1320



 Score = 37.5 bits (83), Expect = 0.18
 Identities = 22/80 (27%), Positives = 42/80 (52%)
 Frame = +2

Query: 251  EYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVR 430
            +Y++ +GD G    +I+ G  +V +TG+D   +V+   E    +G+  L+   P   ++R
Sbjct: 2322 DYILHKGDIGQQLIIIKRGTAEV-ITGED--PEVILPLEEMSFYGDRYLLAPGPHLETLR 2378

Query: 431  AQTAGALWAMDRHTFRRILL 490
            A T   ++ ++R     ILL
Sbjct: 2379 AVTNVDVFILERSDLDEILL 2398


>UniRef50_A7RFM7 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 158

 Score = 45.6 bits (103), Expect = 7e-04
 Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 3/114 (2%)
 Frame = +2

Query: 158 AVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDD 337
           A++ +  F  L     + V    + +     + +++QG   +NFY I +G   V+   D 
Sbjct: 29  ALQTMSSFAELPLHMQESVCKVAWHQSLPANKIIVKQGHLAENFYFIMSGSVTVVSENDP 88

Query: 338 RVEKV---VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILL 490
              +V   V T     SFG+LA++ N  R A+V ++    L  + R  ++RI +
Sbjct: 89  TSGQVFASVATLRRGASFGDLAILKNCTRTATVVSKVPIHLLVISREDYQRIFM 142


>UniRef50_UPI00006D001D Cluster: cation channel family protein; n=1;
            Tetrahymena thermophila SB210|Rep: cation channel family
            protein - Tetrahymena thermophila SB210
          Length = 1201

 Score = 45.2 bits (102), Expect = 9e-04
 Identities = 25/103 (24%), Positives = 51/103 (49%), Gaps = 2/103 (1%)
 Frame = +2

Query: 173  LLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGD-NFYVIENGVFDVLVTGD-DRVE 346
            L   +  ++ +++V+  M E    P E + +Q D  D + Y I++G  ++ V  +  + +
Sbjct: 696  LFMVNFQSKVIKEVVYLMEEIIVAPNEIIFKQNDSEDQSIYFIQSGDVEIFVADNLGQTQ 755

Query: 347  KVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTF 475
            KV+        FGE++    +PR AS R+     ++ ++R  F
Sbjct: 756  KVLAQITSDSVFGEISFFSGLPRTASARSLNLSTIYKINRQKF 798


>UniRef50_Q89W82 Cluster: Bll0811 protein; n=3; Bradyrhizobium|Rep:
           Bll0811 protein - Bradyrhizobium japonicum
          Length = 738

 Score = 45.2 bits (102), Expect = 9e-04
 Identities = 22/91 (24%), Positives = 46/91 (50%)
 Frame = +2

Query: 242 EPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAA 421
           E GE +++ GD  D+ + I +G   +++  +      V +     + GE+ L+   PR+A
Sbjct: 623 EAGEIIVQAGDAADSMHFILDGRVGIMIPAEQNGMTRVRSLGRYTTIGEMGLVSQTPRSA 682

Query: 422 SVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
           +++A+    L+ ++ H F  I  ++    RK
Sbjct: 683 TIQAEVDSVLYVLNTHQFDAIRDEAPALSRK 713


>UniRef50_Q6ANR0 Cluster: Related to nitrogen assimilation
           regulatory protein; n=1; Desulfotalea psychrophila|Rep:
           Related to nitrogen assimilation regulatory protein -
           Desulfotalea psychrophila
          Length = 881

 Score = 45.2 bits (102), Expect = 9e-04
 Identities = 30/114 (26%), Positives = 51/114 (44%)
 Frame = +2

Query: 173 LLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKV 352
           +LF+ L  +++ +  +    +    GEYV RQG   D  Y++  G  +++   D      
Sbjct: 14  VLFQDLSPEEIGRCSEMAMVEIVPMGEYVYRQGGQTDLLYLVAVGEAELVFEFDTSSVSA 73

Query: 353 VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
           V      G FGE AL+   P A +VRA     L       F+ +L ++   +R+
Sbjct: 74  VGRVGPGGHFGETALLTGKPHAVAVRALFDLVLLIFKGSFFKDLLERNQCVRRR 127


>UniRef50_Q5P0W6 Cluster: Transcriptional regulator, Dnr/Nnr type;
           n=2; Azoarcus|Rep: Transcriptional regulator, Dnr/Nnr
           type - Azoarcus sp. (strain EbN1) (Aromatoleum
           aromaticum (strain EbN1))
          Length = 229

 Score = 45.2 bits (102), Expect = 9e-04
 Identities = 26/90 (28%), Positives = 40/90 (44%)
 Frame = +2

Query: 143 ARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL 322
           A +   +R I  F  L A  + +V     E+  E GE + ++GD    F+ + +G   + 
Sbjct: 6   ADIPTLLRQISFFSELSADDIDRVARYTRERTLEKGEVLFQRGDPVHGFFFVVSGQMKLA 65

Query: 323 VTGDDRVEKVVHTYEGSGSFGELALMYNMP 412
           V+     EKVV       SFGE  +  N P
Sbjct: 66  VSSAQGNEKVVEIISPMNSFGEAVMFLNRP 95


>UniRef50_Q2S8X4 Cluster: CAMP-binding protein-catabolite gene
           activator and regulatory subunit of cAMP-dependent
           protein kinase; n=1; Hahella chejuensis KCTC 2396|Rep:
           CAMP-binding protein-catabolite gene activator and
           regulatory subunit of cAMP-dependent protein kinase -
           Hahella chejuensis (strain KCTC 2396)
          Length = 263

 Score = 45.2 bits (102), Expect = 9e-04
 Identities = 28/80 (35%), Positives = 45/80 (56%)
 Frame = +2

Query: 236 RSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPR 415
           R +PG+ +IRQG++ DN Y +  G  D  V  D+  ++V   +EG   FG +A + N PR
Sbjct: 153 RYKPGDVIIRQGEEADNVYTMMKG--DAKVFIDE--QEVGEVHEGE-IFGAIAALTNAPR 207

Query: 416 AASVRAQTAGALWAMDRHTF 475
            A+V A  +  + A+ +  F
Sbjct: 208 NATVVAGNSCTVMAVPKTQF 227


>UniRef50_Q1YDY1 Cluster: Putative cyclic nucleotide-binding
           protein; n=2; Aurantimonadaceae|Rep: Putative cyclic
           nucleotide-binding protein - Aurantimonas sp. SI85-9A1
          Length = 151

 Score = 45.2 bits (102), Expect = 9e-04
 Identities = 34/109 (31%), Positives = 49/109 (44%)
 Frame = +2

Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
           +R + LF  L A Q++ +      +R    E+V R+    D   VI +G    L+ G   
Sbjct: 10  LRNVPLFEDLHADQLRLLAFGAERRRLHRDEFVFREDARSDAGLVIVSGEI-ALLRGRPA 68

Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
            + VV TY      GE+AL+    R  S R  T   L  + R  FRR+L
Sbjct: 69  HQTVVGTYGPGTLLGEMALITETRRPTSARTLTDCELIRITRPLFRRML 117


>UniRef50_Q13J41 Cluster: Transcriptional regulator, Crp/Fnr family;
           n=5; Burkholderiaceae|Rep: Transcriptional regulator,
           Crp/Fnr family - Burkholderia xenovorans (strain LB400)
          Length = 237

 Score = 45.2 bits (102), Expect = 9e-04
 Identities = 29/114 (25%), Positives = 49/114 (42%)
 Frame = +2

Query: 146 RLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV 325
           +LA  +     FRS  A    Q+++A   +R   G+ +  +GD  D  Y + +G+  +  
Sbjct: 9   KLAAVLERSAWFRSAPATMQAQLVEAGRLERLAAGQRLFTRGDSDDGLYCVLDGLVRIGA 68

Query: 326 TGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
                 E ++   E    FGE+AL  N PR     A+    L+ + R     +L
Sbjct: 69  ASSAGKEALLAVIEPVNWFGEIALFDNRPRTHDAYAERDSELFHVPRAALAALL 122


>UniRef50_A0XC88 Cluster: Cyclic nucleotide-binding; n=1;
           Dinoroseobacter shibae DFL 12|Rep: Cyclic
           nucleotide-binding - Dinoroseobacter shibae DFL 12
          Length = 733

 Score = 45.2 bits (102), Expect = 9e-04
 Identities = 29/93 (31%), Positives = 47/93 (50%), Gaps = 1/93 (1%)
 Frame = +2

Query: 191 DAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV-TGDDRVEKVVHTYE 367
           DA   Q+VL  M  +    G+ ++  GD   +  ++E G   VL  T D R+ ++     
Sbjct: 602 DAALAQRVLSMMTREEVAAGQRLMACGDRDTDVILVERGQLAVLAPTPDGRMRRIQSLRP 661

Query: 368 GSGSFGELALMYNMPRAASVRAQTAGALWAMDR 466
           G+   GE+A    +PRAA V A+TA  ++  +R
Sbjct: 662 GA-LIGEIASYAGLPRAADVIAETAATVYRFNR 693


>UniRef50_A7RK87 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 573

 Score = 45.2 bits (102), Expect = 9e-04
 Identities = 29/123 (23%), Positives = 59/123 (47%), Gaps = 1/123 (0%)
 Frame = +2

Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIEN 304
           +++ Q A++  ++R I  F     +   ++++  + +       ++RQG     FY + +
Sbjct: 165 RTEQQCAKVLFSLRSIRAFAEYPQRIQHKLINVGWYESHSSKRAILRQGQIPQAFYFVLS 224

Query: 305 GVFDVLVTGD-DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRR 481
           G   V V G+ D   + VH      SFGELA++++  R ++V ++    L  + R  F  
Sbjct: 225 GSAVVTVLGEHDTFARTVHFLRRGDSFGELAILHDTQRQSTVISREPIELLVISREDFID 284

Query: 482 ILL 490
           I +
Sbjct: 285 IFM 287


>UniRef50_A0E001 Cluster: Chromosome undetermined scaffold_70, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_70,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 467

 Score = 45.2 bits (102), Expect = 9e-04
 Identities = 31/95 (32%), Positives = 49/95 (51%), Gaps = 16/95 (16%)
 Frame = +2

Query: 248 GEYVIRQGDDGDNFYVIENG---VFDVLVTGD-------------DRVEKVVHTYEGSGS 379
           GE + R+GD GD FY+I  G   V+   V  +             D+  K+ H  EG  +
Sbjct: 67  GEIICREGDKGDKFYIILQGNVSVYRKNVNSNYEPNSVLSEQIFMDQNVKIGHLKEGE-T 125

Query: 380 FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484
           FGELAL  N PR A+++AQ+   L ++ +  + ++
Sbjct: 126 FGELALSLNKPRFATIKAQSTVILCSLSKDNYAKM 160


>UniRef50_A0DVS8 Cluster: Chromosome undetermined scaffold_66, whole
           genome shotgun sequence; n=5; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_66,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 637

 Score = 45.2 bits (102), Expect = 9e-04
 Identities = 26/66 (39%), Positives = 40/66 (60%), Gaps = 4/66 (6%)
 Frame = +2

Query: 248 GEYVIRQGDDGDNFYVIENGVFDV----LVTGDDRVEKVVHTYEGSGSFGELALMYNMPR 415
           G+ + R+GD G  FY+I  G   +    LV  + + ++++   +G G FGELAL  N PR
Sbjct: 106 GQTLFREGDVGTTFYIILQGRVSIHKRLLVQEEFQDKELIQLQDGQG-FGELALENNEPR 164

Query: 416 AASVRA 433
           +ASV+A
Sbjct: 165 SASVKA 170


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 545,932,510
Number of Sequences: 1657284
Number of extensions: 11821154
Number of successful extensions: 55057
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 50874
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 54721
length of database: 575,637,011
effective HSP length: 95
effective length of database: 418,195,031
effective search space used: 31782822356
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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