Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= epV30235
(516 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X14968-1|CAA33094.1| 404|Homo sapiens protein ( Human testis mR... 190 2e-48
BT007225-1|AAP35889.1| 382|Homo sapiens protein kinase, cAMP-de... 190 2e-48
BC002763-1|AAH02763.1| 382|Homo sapiens PRKAR2A protein protein. 190 2e-48
M31158-1|AAA60099.1| 418|Homo sapiens cAMP-dependent protein ki... 189 6e-48
BC075800-1|AAH75800.1| 418|Homo sapiens protein kinase, cAMP-de... 189 6e-48
AC006387-1|AAS07389.1| 306|Homo sapiens unknown protein. 189 6e-48
M65066-1|AAC37564.1| 380|Homo sapiens cAMP-dependent protein ki... 127 3e-29
BC036828-1|AAH36828.2| 381|Homo sapiens protein kinase, cAMP-de... 127 3e-29
BC026734-1|AAH26734.1| 381|Homo sapiens PRKAR1B protein protein. 127 3e-29
M33336-1|AAB50921.1| 381|Homo sapiens cAMP-dependent protein ki... 126 3e-29
M18468-1|AAB50922.1| 381|Homo sapiens cAMP-dependent protein ki... 126 3e-29
BC093042-1|AAH93042.1| 381|Homo sapiens protein kinase, cAMP-de... 126 3e-29
BC036285-1|AAH36285.1| 381|Homo sapiens protein kinase, cAMP-de... 126 3e-29
L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP ... 119 5e-27
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 81 2e-15
D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein ki... 81 2e-15
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 80 4e-15
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 73 5e-13
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 73 5e-13
EF560730-1|ABQ59040.1| 686|Homo sapiens PRKG1 protein protein. 73 5e-13
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 73 5e-13
BC062688-1|AAH62688.1| 312|Homo sapiens PRKG1 protein protein. 73 5e-13
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 73 5e-13
AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase, cGMP-de... 73 5e-13
AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase, cGMP-de... 73 5e-13
AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase, cGMP-de... 73 5e-13
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 71 3e-12
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 71 3e-12
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 71 3e-12
AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase, cGMP-de... 71 3e-12
AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase, cGMP-de... 71 3e-12
AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase, cGMP-de... 71 3e-12
EF157730-1|ABO15447.1| 35|Homo sapiens type II cAMP-dependent ... 58 1e-08
AJ238850-1|CAB52754.1| 1203|Homo sapiens hyperpolarization-activ... 57 3e-08
AJ132429-1|CAB42604.1| 1203|Homo sapiens hyperpolarization-activ... 57 3e-08
AJ133727-1|CAB42630.1| 889|Homo sapiens hyperpolarization-activ... 57 4e-08
AJ012582-1|CAB42602.1| 889|Homo sapiens hyperpolarization-activ... 57 4e-08
AF065164-1|AAC28444.2| 889|Homo sapiens hyperpolarization-activ... 57 4e-08
AF064877-1|AAC39760.1| 597|Homo sapiens ion channel BCNG-2 prot... 57 4e-08
AL391378-3|CAI39627.1| 181|Homo sapiens protein kinase, cGMP-de... 53 7e-07
AL157399-3|CAI41306.1| 181|Homo sapiens protein kinase, cGMP-de... 53 7e-07
AF064876-1|AAC39759.1| 749|Homo sapiens ion channel BCNG-1 prot... 52 9e-07
AF488549-1|AAO49469.1| 890|Homo sapiens hyperpolarization activ... 50 5e-06
U78516-1|AAD03422.1| 1011|Homo sapiens cAMP-regulated guanine nu... 49 8e-06
BC040183-1|AAH40183.1| 867|Homo sapiens RAPGEF4 protein protein. 49 8e-06
BC028024-1|AAH28024.2| 450|Homo sapiens HCN3 protein protein. 49 8e-06
BC024004-1|AAH24004.1| 1011|Homo sapiens Rap guanine nucleotide ... 49 8e-06
BC000066-1|AAH00066.1| 571|Homo sapiens Unknown (protein for IM... 49 8e-06
AL713999-31|CAI95100.1| 774|Homo sapiens hyperpolarization acti... 49 8e-06
AF488550-1|AAO49470.1| 774|Homo sapiens hyperpolarization activ... 49 8e-06
AB040968-1|BAA96059.2| 711|Homo sapiens KIAA1535 protein protein. 49 8e-06
AB027471-1|BAB72179.1| 1011|Homo sapiens cAMP-GEFII protein. 49 8e-06
AF272900-1|AAF86274.1| 809|Homo sapiens cone photoreceptor cycl... 48 1e-05
U78169-1|AAD02890.1| 556|Homo sapiens cAMP-regulated guanine nu... 47 3e-05
U78168-1|AAD12740.1| 881|Homo sapiens cAMP-regulated guanine nu... 47 3e-05
BC092404-1|AAH92404.1| 881|Homo sapiens Rap guanine nucleotide ... 47 3e-05
BC068477-1|AAH68477.1| 343|Homo sapiens RAPGEF3 protein protein. 47 3e-05
BC040534-1|AAH40534.1| 321|Homo sapiens RAPGEF3 protein protein. 47 3e-05
BC017728-1|AAH17728.1| 881|Homo sapiens Rap guanine nucleotide ... 47 3e-05
AF103905-1|AAC83381.1| 881|Homo sapiens Rap1 guanine-nucleotide... 47 3e-05
AB209681-1|BAD92918.1| 643|Homo sapiens RAP guanine-nucleotide-... 44 3e-04
AC004492-1|AAC08318.1| 112|Homo sapiens CAMP-DEPENDENT PROTEIN ... 44 4e-04
U58837-1|AAB63387.1| 1251|Homo sapiens cGMP-gated cation channel... 42 0.001
L15297-1|AAA65619.1| 623|Homo sapiens cyclic nucleotide-gated c... 42 0.001
L15296-1|AAA65620.1| 909|Homo sapiens cyclic nucleotide-gated c... 42 0.001
BC040277-1|AAH40277.1| 474|Homo sapiens CNGA4 protein protein. 42 0.001
AF042498-1|AAC04830.1| 1245|Homo sapiens rod photoreceptor CNG-c... 42 0.001
S76069-1|AAD14208.1| 261|Homo sapiens CNG3 protein. 42 0.002
M84741-1|AAA52010.1| 690|Homo sapiens cGMP-gated cation channel... 42 0.002
BC096300-1|AAH96300.1| 694|Homo sapiens cyclic nucleotide gated... 42 0.002
BC096299-1|AAH96299.1| 676|Homo sapiens cyclic nucleotide gated... 42 0.002
BC096298-1|AAH96298.1| 694|Homo sapiens cyclic nucleotide gated... 42 0.002
AK131300-1|BAD18468.1| 698|Homo sapiens mRNA. protein. 42 0.002
AF065314-1|AAC17440.1| 694|Homo sapiens cone photoreceptor cGMP... 42 0.002
AC092675-2|AAY24181.1| 694|Homo sapiens unknown protein. 42 0.002
S76062-1|AAD14206.1| 261|Homo sapiens CNG1 protein. 40 0.004
S42457-1|AAB22778.1| 686|Homo sapiens rod photoreceptor cGMP-ga... 40 0.004
AC107068-3|AAY40919.1| 690|Homo sapiens unknown protein. 40 0.004
AF228520-1|AAF80179.1| 610|Homo sapiens cone photoreceptor cGMP... 40 0.005
S76067-1|AAD14207.1| 261|Homo sapiens CNG2 protein. 39 0.009
BC126304-1|AAI26305.1| 664|Homo sapiens cyclic nucleotide gated... 39 0.009
BC126302-1|AAI26303.1| 664|Homo sapiens cyclic nucleotide gated... 39 0.009
AC009484-1|AAY15071.1| 157|Homo sapiens unknown protein. 39 0.012
BC070478-1|AAH70478.1| 80|Homo sapiens PRKAR1B protein protein. 36 0.064
BC051768-1|AAH51768.1| 1327|Homo sapiens patatin-like phospholip... 33 0.45
BC050553-1|AAH50553.1| 1327|Homo sapiens patatin-like phospholip... 33 0.45
BC038229-1|AAH38229.1| 1332|Homo sapiens PNPLA6 protein protein. 33 0.45
AJ004832-1|CAA06164.1| 1327|Homo sapiens neuropathy target ester... 33 0.45
BC142964-1|AAI42965.1| 827|Homo sapiens RAPGEF6 protein protein. 31 3.2
BC133703-1|AAI33704.1| 1504|Homo sapiens RAPGEF6 protein protein. 31 3.2
BC036847-1|AAH36847.1| 272|Homo sapiens neurogenin 2 protein. 31 3.2
BC011982-1|AAH11982.1| 412|Homo sapiens major facilitator super... 31 3.2
AF478567-1|AAM21637.1| 1601|Homo sapiens PDZ domain-containing g... 31 3.2
AF478469-1|AAL79916.1| 1391|Homo sapiens Rap1 guanine nucleotide... 31 3.2
AF478468-1|AAL79915.1| 1601|Homo sapiens Rap1 guanine nucleotide... 31 3.2
AF414442-1|AAL65133.2|22152|Homo sapiens ovarian cancer related ... 31 3.2
AF394782-1|AAK83368.1| 1509|Homo sapiens rap guanine nucleotide ... 31 3.2
AF303002-1|AAG40770.1| 250|Homo sapiens neurogenin 2 protein. 31 3.2
AF117947-1|AAF22004.1| 1204|Homo sapiens PDZ domain-containing g... 31 3.2
AC004227-1|AAC04379.1| 579|Homo sapiens KIA001LB protein. 31 3.2
AB029009-1|BAA83038.1| 902|Homo sapiens KIAA1086 protein protein. 31 3.2
AF361486-1|AAK74120.3| 6995|Homo sapiens mucin 16 protein. 30 4.2
AB023164-1|BAA76791.3| 2330|Homo sapiens KIAA0947 protein protein. 30 4.2
Z34277-1|CAA84031.1| 477|Homo sapiens mucin protein. 30 5.5
BC117319-1|AAI17320.1| 257|Homo sapiens TPRXL protein protein. 30 5.5
AK223527-1|BAD97247.1| 257|Homo sapiens folate receptor 1 precu... 30 5.5
AJ298318-1|CAC83675.1| 1349|Homo sapiens mucin 5 protein. 29 7.3
Z83844-7|CAI20371.1| 2193|Homo sapiens protein ( S domain contai... 29 9.7
DQ278603-1|ABB77204.1| 2266|Homo sapiens trio-associated repeat ... 29 9.7
DQ228005-1|ABB59561.1| 2365|Homo sapiens TRIOBP isoform 6 protein. 29 9.7
DQ228004-1|ABB59560.1| 1144|Homo sapiens TRIOBP isoform 4 protein. 29 9.7
DQ228003-1|ABB59559.1| 2193|Homo sapiens TRIOBP isoform 3 protein. 29 9.7
BC050522-1|AAH50522.1| 970|Homo sapiens DDX11 protein protein. 29 9.7
AY053503-1|AAL15429.1| 1107|Homo sapiens ether-a-go-go-like pota... 29 9.7
AB209053-1|BAD92290.1| 583|Homo sapiens potassium voltage-gated... 29 9.7
>X14968-1|CAA33094.1| 404|Homo sapiens protein ( Human testis mRNA
for the RII-alpha subunit of cAMP dependent protein
kinase. ).
Length = 404
Score = 190 bits (463), Expect = 2e-48
Identities = 93/164 (56%), Positives = 122/164 (74%)
Frame = +2
Query: 23 PPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQ 202
P +RFN RR SV AETY+P+E++ D + PK+D QR RL EA + ILLF++LD +Q
Sbjct: 89 PVPSRFN-RRVSVCAETYNPDEEEEDTDPRVIHPKTDEQRCRLQEACKDILLFKNLDQEQ 147
Query: 203 MQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF 382
+ QVLDAMFE+ + E+VI QGDDGDNFYVIE G +D+LVT D++ + V Y+ GSF
Sbjct: 148 LSQVLDAMFERIVKADEHVIDQGDDGDNFYVIERGTYDILVTKDNQT-RSVGQYDNRGSF 206
Query: 383 GELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
GELALMYN PRAA++ A + G+LW +DR TFRRI++K+ KKRK
Sbjct: 207 GELALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNAKKRK 250
Score = 70.5 bits (165), Expect = 3e-12
Identities = 41/133 (30%), Positives = 74/133 (55%), Gaps = 9/133 (6%)
Frame = +2
Query: 116 VFPKSDAQRARLAEA-VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFY 292
+ K++A++ ++ E+ + + L +SL+ + +++D + EK + GE +I QG+ D+FY
Sbjct: 240 IIVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFY 299
Query: 293 VIENGVFDVLV--------TGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGA 448
+IE+G +L+ G ++ ++ ++G FGELAL+ N PRAAS A
Sbjct: 300 IIESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQ-YFGELALVTNKPRAASAYAVGDVK 358
Query: 449 LWAMDRHTFRRIL 487
MD F R+L
Sbjct: 359 CLVMDVQAFERLL 371
>BT007225-1|AAP35889.1| 382|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type II, alpha protein.
Length = 382
Score = 190 bits (463), Expect = 2e-48
Identities = 93/164 (56%), Positives = 122/164 (74%)
Frame = +2
Query: 23 PPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQ 202
P +RFN RR SV AETY+P+E++ D + PK+D QR RL EA + ILLF++LD +Q
Sbjct: 89 PVPSRFN-RRVSVCAETYNPDEEEEDTDPRVIHPKTDEQRCRLQEACKDILLFKNLDQEQ 147
Query: 203 MQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF 382
+ QVLDAMFE+ + E+VI QGDDGDNFYVIE G +D+LVT D++ + V Y+ GSF
Sbjct: 148 LSQVLDAMFERIVKADEHVIDQGDDGDNFYVIERGTYDILVTKDNQT-RSVGQYDNRGSF 206
Query: 383 GELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
GELALMYN PRAA++ A + G+LW +DR TFRRI++K+ KKRK
Sbjct: 207 GELALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNAKKRK 250
Score = 44.4 bits (100), Expect = 2e-04
Identities = 36/125 (28%), Positives = 63/125 (50%), Gaps = 1/125 (0%)
Frame = +2
Query: 116 VFPKSDAQRARLAEA-VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFY 292
+ K++A++ ++ E+ + + L +SL+ + +++D + EK + GE +I Q
Sbjct: 240 IIVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQTKSN---- 295
Query: 293 VIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHT 472
++G G+ VE + ++G FGELAL+ N PRAAS A MD
Sbjct: 296 --KDG-------GNQEVE-IARCHKGQ-YFGELALVTNKPRAASAYAVGDVKCLVMDVQA 344
Query: 473 FRRIL 487
F R+L
Sbjct: 345 FERLL 349
>BC002763-1|AAH02763.1| 382|Homo sapiens PRKAR2A protein protein.
Length = 382
Score = 190 bits (463), Expect = 2e-48
Identities = 93/164 (56%), Positives = 122/164 (74%)
Frame = +2
Query: 23 PPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQ 202
P +RFN RR SV AETY+P+E++ D + PK+D QR RL EA + ILLF++LD +Q
Sbjct: 89 PVPSRFN-RRVSVCAETYNPDEEEEDTDPRVIHPKTDEQRCRLQEACKDILLFKNLDQEQ 147
Query: 203 MQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF 382
+ QVLDAMFE+ + E+VI QGDDGDNFYVIE G +D+LVT D++ + V Y+ GSF
Sbjct: 148 LSQVLDAMFERIVKADEHVIDQGDDGDNFYVIERGTYDILVTKDNQT-RSVGQYDNRGSF 206
Query: 383 GELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
GELALMYN PRAA++ A + G+LW +DR TFRRI++K+ KKRK
Sbjct: 207 GELALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNAKKRK 250
Score = 44.4 bits (100), Expect = 2e-04
Identities = 36/125 (28%), Positives = 63/125 (50%), Gaps = 1/125 (0%)
Frame = +2
Query: 116 VFPKSDAQRARLAEA-VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFY 292
+ K++A++ ++ E+ + + L +SL+ + +++D + EK + GE +I Q
Sbjct: 240 IIVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQTKSN---- 295
Query: 293 VIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHT 472
++G G+ VE + ++G FGELAL+ N PRAAS A MD
Sbjct: 296 --KDG-------GNQEVE-IARCHKGQ-YFGELALVTNKPRAASAYAVGDVKCLVMDVQA 344
Query: 473 FRRIL 487
F R+L
Sbjct: 345 FERLL 349
>M31158-1|AAA60099.1| 418|Homo sapiens cAMP-dependent protein
kinase subunit RII-beta protein.
Length = 418
Score = 189 bits (460), Expect = 6e-48
Identities = 94/164 (57%), Positives = 119/164 (72%)
Frame = +2
Query: 23 PPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQ 202
P + RF RR SV AE Y+P+E++ D + + PK+D QR RL EA + ILLF++LD +Q
Sbjct: 104 PVINRFT-RRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQ 162
Query: 203 MQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF 382
M QVLDAMFEK + GE+VI QGDDGDNFYVI+ G FD+ V D V + V Y+ GSF
Sbjct: 163 MSQVLDAMFEKLVKDGEHVIDQGDDGDNFYVIDRGTFDIYVKCDG-VGRCVGNYDNRGSF 221
Query: 383 GELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
GELALMYN PRAA++ A + GALW +DR TFRRI++K+ KKRK
Sbjct: 222 GELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRK 265
Score = 63.7 bits (148), Expect = 4e-10
Identities = 42/131 (32%), Positives = 69/131 (52%), Gaps = 7/131 (5%)
Frame = +2
Query: 116 VFPKSDAQRARLAEA-VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFY 292
+ K++A++ ++ E+ + + +SL+ + +V+D + K GE +I QGD D+F+
Sbjct: 255 IIVKNNAKKRKMYESFIESLPFLKSLEFSERLKVVDVIGTKVYNDGEQIIAQGDSADSFF 314
Query: 293 VIENGVFDVLV--TGDDRVEK--VVHTYEGSGS--FGELALMYNMPRAASVRAQTAGALW 454
++E+G + + G VE+ V S FGELAL+ N PRAAS A
Sbjct: 315 IVESGEVKITMKRKGKSEVEENGAVEMPRCSRGQYFGELALVTNKPRAASAHAIGTVKCL 374
Query: 455 AMDRHTFRRIL 487
AMD F R+L
Sbjct: 375 AMDVQAFERLL 385
>BC075800-1|AAH75800.1| 418|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type II, beta protein.
Length = 418
Score = 189 bits (460), Expect = 6e-48
Identities = 94/164 (57%), Positives = 119/164 (72%)
Frame = +2
Query: 23 PPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQ 202
P + RF RR SV AE Y+P+E++ D + + PK+D QR RL EA + ILLF++LD +Q
Sbjct: 104 PVINRFT-RRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQ 162
Query: 203 MQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF 382
M QVLDAMFEK + GE+VI QGDDGDNFYVI+ G FD+ V D V + V Y+ GSF
Sbjct: 163 MSQVLDAMFEKLVKDGEHVIDQGDDGDNFYVIDRGTFDIYVKCDG-VGRCVGNYDNRGSF 221
Query: 383 GELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
GELALMYN PRAA++ A + GALW +DR TFRRI++K+ KKRK
Sbjct: 222 GELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRK 265
Score = 64.1 bits (149), Expect = 3e-10
Identities = 41/132 (31%), Positives = 69/132 (52%), Gaps = 8/132 (6%)
Frame = +2
Query: 116 VFPKSDAQRARLAEA-VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFY 292
+ K++A++ ++ E+ + + +SL+ + +V+D + K GE +I QGD D+F+
Sbjct: 255 IIVKNNAKKRKMYESFIESLPFLKSLEFSERLKVVDVIGTKVYNDGEQIIAQGDSADSFF 314
Query: 293 VIENGVFDVLV--TGDDRVE-----KVVHTYEGSGSFGELALMYNMPRAASVRAQTAGAL 451
++E+G + + G VE ++ G FGELAL+ N PRAAS A
Sbjct: 315 IVESGEVKITMKRKGKSEVEENGAVEIARCSRGQ-YFGELALVTNKPRAASAHAIGTVKC 373
Query: 452 WAMDRHTFRRIL 487
AMD F R+L
Sbjct: 374 LAMDVQAFERLL 385
>AC006387-1|AAS07389.1| 306|Homo sapiens unknown protein.
Length = 306
Score = 189 bits (460), Expect = 6e-48
Identities = 94/164 (57%), Positives = 119/164 (72%)
Frame = +2
Query: 23 PPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQ 202
P + RF RR SV AE Y+P+E++ D + + PK+D QR RL EA + ILLF++LD +Q
Sbjct: 104 PVINRFT-RRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQ 162
Query: 203 MQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSF 382
M QVLDAMFEK + GE+VI QGDDGDNFYVI+ G FD+ V D V + V Y+ GSF
Sbjct: 163 MSQVLDAMFEKLVKDGEHVIDQGDDGDNFYVIDRGTFDIYVKCDG-VGRCVGNYDNRGSF 221
Query: 383 GELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
GELALMYN PRAA++ A + GALW +DR TFRRI++K+ KKRK
Sbjct: 222 GELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRK 265
>M65066-1|AAC37564.1| 380|Homo sapiens cAMP-dependent protein
kinase RI-beta regulatory subunit protein.
Length = 380
Score = 127 bits (306), Expect = 3e-29
Identities = 73/163 (44%), Positives = 96/163 (58%)
Frame = +2
Query: 26 PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQM 205
PV + RR V AE Y E+D+ V PK LA+A+ +LF LD +
Sbjct: 88 PVVKARRRRGGVSAEVYT--EEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNER 145
Query: 206 QQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFG 385
+ DAMF GE VI+QG++GDNFYV++ G DV V G E V + EG GSFG
Sbjct: 146 SDIFDAMFPVTHIAGETVIQQGNEGDNFYVVDQGEVDVYVNG----EWVTNISEG-GSFG 200
Query: 386 ELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
ELAL+Y PRAA+V+A+T LW +DR ++RRIL+ S +KRK
Sbjct: 201 ELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRK 243
Score = 62.9 bits (146), Expect = 6e-10
Identities = 40/118 (33%), Positives = 59/118 (50%), Gaps = 1/118 (0%)
Frame = +2
Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316
+R E + + + SL+ + V D + + E GE ++ QG+ GD+FY+I G
Sbjct: 241 KRKMYEEFLSKVSILESLEKWERLTVADRLEPVQFEDGEKIVVQGEPGDDFYIITEGTAS 300
Query: 317 VLVTGDDRVEKV-VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
VL E V V S FGE+AL+ N PRAA+V A+ +DR F R+L
Sbjct: 301 VLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVL 358
>BC036828-1|AAH36828.2| 381|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type I, beta protein.
Length = 381
Score = 127 bits (306), Expect = 3e-29
Identities = 73/163 (44%), Positives = 96/163 (58%)
Frame = +2
Query: 26 PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQM 205
PV + RR V AE Y E+D+ V PK LA+A+ +LF LD +
Sbjct: 89 PVVKARRRRGGVSAEVYT--EEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNER 146
Query: 206 QQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFG 385
+ DAMF GE VI+QG++GDNFYV++ G DV V G E V + EG GSFG
Sbjct: 147 SDIFDAMFPVTHIAGETVIQQGNEGDNFYVVDQGEVDVYVNG----EWVTNISEG-GSFG 201
Query: 386 ELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
ELAL+Y PRAA+V+A+T LW +DR ++RRIL+ S +KRK
Sbjct: 202 ELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRK 244
Score = 64.9 bits (151), Expect = 2e-10
Identities = 41/118 (34%), Positives = 60/118 (50%), Gaps = 1/118 (0%)
Frame = +2
Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316
+R E + + + SL+ + V DA+ + E GE ++ QG+ GD+FY+I G
Sbjct: 242 KRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTAS 301
Query: 317 VLVTGDDRVEKV-VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
VL E V V S FGE+AL+ N PRAA+V A+ +DR F R+L
Sbjct: 302 VLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVL 359
>BC026734-1|AAH26734.1| 381|Homo sapiens PRKAR1B protein protein.
Length = 381
Score = 127 bits (306), Expect = 3e-29
Identities = 73/163 (44%), Positives = 96/163 (58%)
Frame = +2
Query: 26 PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQM 205
PV + RR V AE Y E+D+ V PK LA+A+ +LF LD +
Sbjct: 89 PVVKARRRRGGVSAEVYT--EEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNER 146
Query: 206 QQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFG 385
+ DAMF GE VI+QG++GDNFYV++ G DV V G E V + EG GSFG
Sbjct: 147 SDIFDAMFPVTHIAGETVIQQGNEGDNFYVVDQGEVDVYVNG----EWVTNISEG-GSFG 201
Query: 386 ELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
ELAL+Y PRAA+V+A+T LW +DR ++RRIL+ S +KRK
Sbjct: 202 ELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRK 244
Score = 64.9 bits (151), Expect = 2e-10
Identities = 41/118 (34%), Positives = 60/118 (50%), Gaps = 1/118 (0%)
Frame = +2
Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316
+R E + + + SL+ + V DA+ + E GE ++ QG+ GD+FY+I G
Sbjct: 242 KRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTAS 301
Query: 317 VLVTGDDRVEKV-VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
VL E V V S FGE+AL+ N PRAA+V A+ +DR F R+L
Sbjct: 302 VLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVL 359
>M33336-1|AAB50921.1| 381|Homo sapiens cAMP-dependent protein
kinase type I-alpha subunit protein.
Length = 381
Score = 126 bits (305), Expect = 3e-29
Identities = 73/163 (44%), Positives = 95/163 (58%)
Frame = +2
Query: 26 PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQM 205
PV + RR ++ AE Y E+D+ V PK A LA+A+ +LF LD +
Sbjct: 89 PVVKGRRRRGAISAEVYT--EEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNER 146
Query: 206 QQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFG 385
+ DAMF GE VI+QGD+GDNFYVI+ G DV V E EG GSFG
Sbjct: 147 SDIFDAMFSVSFIAGETVIQQGDEGDNFYVIDQGETDVYVNN----EWATSVGEG-GSFG 201
Query: 386 ELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
ELAL+Y PRAA+V+A+T LW +DR ++RRIL+ S +KRK
Sbjct: 202 ELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRK 244
Score = 61.7 bits (143), Expect = 1e-09
Identities = 40/118 (33%), Positives = 60/118 (50%), Gaps = 1/118 (0%)
Frame = +2
Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316
+R E + + + SLD + V DA+ + E G+ ++ QG+ GD F++I G
Sbjct: 242 KRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAA 301
Query: 317 VLVTGDDRVEKV-VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
VL + E V V S FGE+AL+ N PRAA+V A+ +DR F R+L
Sbjct: 302 VLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVL 359
>M18468-1|AAB50922.1| 381|Homo sapiens cAMP-dependent protein
kinase regulatory subunit type 1 protein.
Length = 381
Score = 126 bits (305), Expect = 3e-29
Identities = 73/163 (44%), Positives = 95/163 (58%)
Frame = +2
Query: 26 PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQM 205
PV + RR ++ AE Y E+D+ V PK A LA+A+ +LF LD +
Sbjct: 89 PVVKGRRRRGAISAEVYT--EEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNER 146
Query: 206 QQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFG 385
+ DAMF GE VI+QGD+GDNFYVI+ G DV V E EG GSFG
Sbjct: 147 SDIFDAMFSVSFIAGETVIQQGDEGDNFYVIDQGETDVYVNN----EWATSVGEG-GSFG 201
Query: 386 ELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
ELAL+Y PRAA+V+A+T LW +DR ++RRIL+ S +KRK
Sbjct: 202 ELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRK 244
Score = 61.7 bits (143), Expect = 1e-09
Identities = 40/118 (33%), Positives = 60/118 (50%), Gaps = 1/118 (0%)
Frame = +2
Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316
+R E + + + SLD + V DA+ + E G+ ++ QG+ GD F++I G
Sbjct: 242 KRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAA 301
Query: 317 VLVTGDDRVEKV-VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
VL + E V V S FGE+AL+ N PRAA+V A+ +DR F R+L
Sbjct: 302 VLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVL 359
>BC093042-1|AAH93042.1| 381|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type I, alpha (tissue
specific exti protein.
Length = 381
Score = 126 bits (305), Expect = 3e-29
Identities = 73/163 (44%), Positives = 95/163 (58%)
Frame = +2
Query: 26 PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQM 205
PV + RR ++ AE Y E+D+ V PK A LA+A+ +LF LD +
Sbjct: 89 PVVKGRRRRGAISAEVYT--EEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNER 146
Query: 206 QQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFG 385
+ DAMF GE VI+QGD+GDNFYVI+ G DV V E EG GSFG
Sbjct: 147 SDIFDAMFSVSFIAGETVIQQGDEGDNFYVIDQGETDVYVNN----EWATSVGEG-GSFG 201
Query: 386 ELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
ELAL+Y PRAA+V+A+T LW +DR ++RRIL+ S +KRK
Sbjct: 202 ELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRK 244
Score = 61.7 bits (143), Expect = 1e-09
Identities = 40/118 (33%), Positives = 60/118 (50%), Gaps = 1/118 (0%)
Frame = +2
Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316
+R E + + + SLD + V DA+ + E G+ ++ QG+ GD F++I G
Sbjct: 242 KRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAA 301
Query: 317 VLVTGDDRVEKV-VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
VL + E V V S FGE+AL+ N PRAA+V A+ +DR F R+L
Sbjct: 302 VLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVL 359
>BC036285-1|AAH36285.1| 381|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type I, alpha (tissue
specific exti protein.
Length = 381
Score = 126 bits (305), Expect = 3e-29
Identities = 73/163 (44%), Positives = 95/163 (58%)
Frame = +2
Query: 26 PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQM 205
PV + RR ++ AE Y E+D+ V PK A LA+A+ +LF LD +
Sbjct: 89 PVVKGRRRRGAISAEVYT--EEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNER 146
Query: 206 QQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFG 385
+ DAMF GE VI+QGD+GDNFYVI+ G DV V E EG GSFG
Sbjct: 147 SDIFDAMFSVSFIAGETVIQQGDEGDNFYVIDQGETDVYVNN----EWATSVGEG-GSFG 201
Query: 386 ELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKRK 514
ELAL+Y PRAA+V+A+T LW +DR ++RRIL+ S +KRK
Sbjct: 202 ELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRK 244
Score = 61.7 bits (143), Expect = 1e-09
Identities = 40/118 (33%), Positives = 60/118 (50%), Gaps = 1/118 (0%)
Frame = +2
Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFD 316
+R E + + + SLD + V DA+ + E G+ ++ QG+ GD F++I G
Sbjct: 242 KRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAA 301
Query: 317 VLVTGDDRVEKV-VHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
VL + E V V S FGE+AL+ N PRAA+V A+ +DR F R+L
Sbjct: 302 VLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVL 359
>L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP
protein kinase A subunit RI protein.
Length = 593
Score = 119 bits (287), Expect = 5e-27
Identities = 69/156 (44%), Positives = 91/156 (58%)
Frame = +2
Query: 26 PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQM 205
PV + RR ++ AE Y E+D+ V PK A LA+A+ +LF LD +
Sbjct: 89 PVVKGRRRRGAISAEVYT--EEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNER 146
Query: 206 QQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFG 385
+ DAMF GE VI+QGD+GDNFYVI+ G DV V E EG GSFG
Sbjct: 147 SDIFDAMFSVSFIAGETVIQQGDEGDNFYVIDQGETDVYVNN----EWATSVGEG-GSFG 201
Query: 386 ELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLK 493
ELAL+Y PRAA+V+A+T LW +DR ++RRIL++
Sbjct: 202 ELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILME 237
>X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent
protein kinase protein.
Length = 762
Score = 81.0 bits (191), Expect = 2e-15
Identities = 42/143 (29%), Positives = 79/143 (55%)
Frame = +2
Query: 71 TYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPG 250
TYD + A K +++ + +A+ + LD QQ++ +++ M+ + + G
Sbjct: 133 TYDLNKPPEFSFEKARVRKDSSEKKLITDALNKNQFLKRLDPQQIKDMVECMYGRNYQQG 192
Query: 251 EYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVR 430
Y+I+QG+ G++ +V+ G +V + EK++ + +FGELA++YN R ASV+
Sbjct: 193 SYIIKQGEPGNHIFVLAEGRLEVF-----QGEKLLSSIPMWTTFGELAILYNCTRTASVK 247
Query: 431 AQTAGALWAMDRHTFRRILLKSA 499
A T WA+DR F+ I+ ++A
Sbjct: 248 AITNVKTWALDREVFQNIMRRTA 270
Score = 53.6 bits (123), Expect = 4e-07
Identities = 29/110 (26%), Positives = 62/110 (56%), Gaps = 3/110 (2%)
Frame = +2
Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL--VTGD 334
+R + L ++L ++ +++D + + + G+Y+IR+G++G F+++ G V G
Sbjct: 281 LRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGH 340
Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAG-ALWAMDRHTFRR 481
D+ +++ T + FGE AL+ + R+A++ A+ A +DR TF +
Sbjct: 341 DQ-PQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETFNQ 389
>D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein
kinase II protein.
Length = 762
Score = 81.0 bits (191), Expect = 2e-15
Identities = 42/143 (29%), Positives = 79/143 (55%)
Frame = +2
Query: 71 TYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPG 250
TYD + A K +++ + +A+ + LD QQ++ +++ M+ + + G
Sbjct: 133 TYDLNKPPEFSFEKARVRKDSSEKKLITDALNKNQFLKRLDPQQIKDMVECMYGRNYQQG 192
Query: 251 EYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVR 430
Y+I+QG+ G++ +V+ G +V + EK++ + +FGELA++YN R ASV+
Sbjct: 193 SYIIKQGEPGNHIFVLAEGRLEVF-----QGEKLLSSIPMWTTFGELAILYNCTRTASVK 247
Query: 431 AQTAGALWAMDRHTFRRILLKSA 499
A T WA+DR F+ I+ ++A
Sbjct: 248 AITNVKTWALDREVFQNIMRRTA 270
Score = 53.6 bits (123), Expect = 4e-07
Identities = 29/110 (26%), Positives = 62/110 (56%), Gaps = 3/110 (2%)
Frame = +2
Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL--VTGD 334
+R + L ++L ++ +++D + + + G+Y+IR+G++G F+++ G V G
Sbjct: 281 LRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGH 340
Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAG-ALWAMDRHTFRR 481
D+ +++ T + FGE AL+ + R+A++ A+ A +DR TF +
Sbjct: 341 DQ-PQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETFNQ 389
>Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein
kinase protein.
Length = 734
Score = 80.2 bits (189), Expect = 4e-15
Identities = 42/143 (29%), Positives = 78/143 (54%)
Frame = +2
Query: 71 TYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPG 250
TYD + A K ++ + +A+ + LD QQ++ +++ M+ + + G
Sbjct: 133 TYDLNKPPEFSFEKARVRKDSIEKKLITDALNKNQFLKRLDPQQIKDMVECMYGRNYQQG 192
Query: 251 EYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVR 430
Y+I+QG+ G++ +V+ G +V + EK++ + +FGELA++YN R ASV+
Sbjct: 193 SYIIKQGEPGNHIFVLAEGRLEVF-----QGEKLLSSIPMWTTFGELAILYNCTRTASVK 247
Query: 431 AQTAGALWAMDRHTFRRILLKSA 499
A T WA+DR F+ I+ ++A
Sbjct: 248 AITNVKTWALDREVFQNIMRRTA 270
Score = 53.6 bits (123), Expect = 4e-07
Identities = 29/110 (26%), Positives = 62/110 (56%), Gaps = 3/110 (2%)
Frame = +2
Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVL--VTGD 334
+R + L ++L ++ +++D + + + G+Y+IR+G++G F+++ G V G
Sbjct: 281 LRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGH 340
Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAG-ALWAMDRHTFRR 481
D+ +++ T + FGE AL+ + R+A++ A+ A +DR TF +
Sbjct: 341 DQ-PQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETFNQ 389
>Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein
kinase type I beta protein.
Length = 686
Score = 73.3 bits (172), Expect = 5e-13
Identities = 45/155 (29%), Positives = 78/155 (50%), Gaps = 1/155 (0%)
Frame = +2
Query: 47 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226
+R+++ AE + D +PKS + + EA+ ++L+ Q+Q+++D M
Sbjct: 75 KRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCM 134
Query: 227 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMY 403
+ +I++GD G YV+E+G +V G V G G FGELA++Y
Sbjct: 135 YPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILY 188
Query: 404 NMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKK 508
N R A+V+ LWA+DR F+ I++++ K
Sbjct: 189 NCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIK 223
Score = 60.9 bits (141), Expect = 3e-09
Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 1/112 (0%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
E ++ + F+SL + + ++ D + E E GEY+IRQG GD F++I G +V
Sbjct: 229 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 288
Query: 335 DRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
+ V G G FGE AL R A+V A A +DR +F+ ++
Sbjct: 289 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLI 340
>Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for
type I beta cGMP-dependent protein kinase (EC
2.7.1.37). ).
Length = 686
Score = 73.3 bits (172), Expect = 5e-13
Identities = 45/155 (29%), Positives = 78/155 (50%), Gaps = 1/155 (0%)
Frame = +2
Query: 47 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226
+R+++ AE + D +PKS + + EA+ ++L+ Q+Q+++D M
Sbjct: 75 KRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCM 134
Query: 227 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMY 403
+ +I++GD G YV+E+G +V G V G G FGELA++Y
Sbjct: 135 YPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILY 188
Query: 404 NMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKK 508
N R A+V+ LWA+DR F+ I++++ K
Sbjct: 189 NCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIK 223
Score = 60.9 bits (141), Expect = 3e-09
Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 1/112 (0%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
E ++ + F+SL + + ++ D + E E GEY+IRQG GD F++I G +V
Sbjct: 229 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 288
Query: 335 DRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
+ V G G FGE AL R A+V A A +DR +F+ ++
Sbjct: 289 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLI 340
>EF560730-1|ABQ59040.1| 686|Homo sapiens PRKG1 protein protein.
Length = 686
Score = 73.3 bits (172), Expect = 5e-13
Identities = 44/154 (28%), Positives = 78/154 (50%)
Frame = +2
Query: 47 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226
+R+++ AE + D +PKS + + EA+ ++L+ Q+Q+++D M
Sbjct: 75 KRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCM 134
Query: 227 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYN 406
+ +I++GD G YV+E+G +V G K+ G FGELA++YN
Sbjct: 135 YPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEG----AKLCTMGPGK-VFGELAILYN 189
Query: 407 MPRAASVRAQTAGALWAMDRHTFRRILLKSAFKK 508
R A+V+ LWA+DR F+ I++++ K
Sbjct: 190 CTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIK 223
Score = 60.9 bits (141), Expect = 3e-09
Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 1/112 (0%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
E ++ + F+SL + + ++ D + E E GEY+IRQG GD F++I G +V
Sbjct: 229 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 288
Query: 335 DRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
+ V G G FGE AL R A+V A A +DR +F+ ++
Sbjct: 289 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLI 340
>BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 73.3 bits (172), Expect = 5e-13
Identities = 45/155 (29%), Positives = 78/155 (50%), Gaps = 1/155 (0%)
Frame = +2
Query: 47 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226
+R+++ AE + D +PKS + + EA+ ++L+ Q+Q+++D M
Sbjct: 75 KRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCM 134
Query: 227 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMY 403
+ +I++GD G YV+E+G +V G V G G FGELA++Y
Sbjct: 135 YPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILY 188
Query: 404 NMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKK 508
N R A+V+ LWA+DR F+ I++++ K
Sbjct: 189 NCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIK 223
Score = 60.9 bits (141), Expect = 3e-09
Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 1/112 (0%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
E ++ + F+SL + + ++ D + E E GEY+IRQG GD F++I G +V
Sbjct: 229 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 288
Query: 335 DRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
+ V G G FGE AL R A+V A A +DR +F+ ++
Sbjct: 289 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLI 340
>BC062688-1|AAH62688.1| 312|Homo sapiens PRKG1 protein protein.
Length = 312
Score = 73.3 bits (172), Expect = 5e-13
Identities = 45/155 (29%), Positives = 78/155 (50%), Gaps = 1/155 (0%)
Frame = +2
Query: 47 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226
+R+++ AE + D +PKS + + EA+ ++L+ Q+Q+++D M
Sbjct: 75 KRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCM 134
Query: 227 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMY 403
+ +I++GD G YV+E+G +V G V G G FGELA++Y
Sbjct: 135 YPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILY 188
Query: 404 NMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKK 508
N R A+V+ LWA+DR F+ I++++ K
Sbjct: 189 NCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIK 223
Score = 50.0 bits (114), Expect = 5e-06
Identities = 28/82 (34%), Positives = 42/82 (51%), Gaps = 1/82 (1%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
E ++ + F+SL + + ++ D + E E GEY+IRQG GD F++I G +V
Sbjct: 229 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 288
Query: 335 DRVEKVVHTYEGSGS-FGELAL 397
+ V G G FGE AL
Sbjct: 289 PSEDPVFLRTLGKGDWFGEKAL 310
>AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 73.3 bits (172), Expect = 5e-13
Identities = 45/155 (29%), Positives = 78/155 (50%), Gaps = 1/155 (0%)
Frame = +2
Query: 47 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226
+R+++ AE + D +PKS + + EA+ ++L+ Q+Q+++D M
Sbjct: 75 KRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCM 134
Query: 227 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMY 403
+ +I++GD G YV+E+G +V G V G G FGELA++Y
Sbjct: 135 YPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILY 188
Query: 404 NMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKK 508
N R A+V+ LWA+DR F+ I++++ K
Sbjct: 189 NCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIK 223
Score = 60.9 bits (141), Expect = 3e-09
Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 1/112 (0%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
E ++ + F+SL + + ++ D + E E GEY+IRQG GD F++I G +V
Sbjct: 229 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 288
Query: 335 DRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
+ V G G FGE AL R A+V A A +DR +F+ ++
Sbjct: 289 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLI 340
>AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 73.3 bits (172), Expect = 5e-13
Identities = 45/155 (29%), Positives = 78/155 (50%), Gaps = 1/155 (0%)
Frame = +2
Query: 47 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226
+R+++ AE + D +PKS + + EA+ ++L+ Q+Q+++D M
Sbjct: 75 KRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCM 134
Query: 227 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMY 403
+ +I++GD G YV+E+G +V G V G G FGELA++Y
Sbjct: 135 YPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILY 188
Query: 404 NMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKK 508
N R A+V+ LWA+DR F+ I++++ K
Sbjct: 189 NCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIK 223
Score = 60.9 bits (141), Expect = 3e-09
Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 1/112 (0%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
E ++ + F+SL + + ++ D + E E GEY+IRQG GD F++I G +V
Sbjct: 229 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 288
Query: 335 DRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
+ V G G FGE AL R A+V A A +DR +F+ ++
Sbjct: 289 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLI 340
>AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 73.3 bits (172), Expect = 5e-13
Identities = 45/155 (29%), Positives = 78/155 (50%), Gaps = 1/155 (0%)
Frame = +2
Query: 47 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226
+R+++ AE + D +PKS + + EA+ ++L+ Q+Q+++D M
Sbjct: 75 KRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCM 134
Query: 227 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMY 403
+ +I++GD G YV+E+G +V G V G G FGELA++Y
Sbjct: 135 YPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILY 188
Query: 404 NMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKK 508
N R A+V+ LWA+DR F+ I++++ K
Sbjct: 189 NCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIK 223
Score = 60.9 bits (141), Expect = 3e-09
Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 1/112 (0%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
E ++ + F+SL + + ++ D + E E GEY+IRQG GD F++I G +V
Sbjct: 229 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 288
Query: 335 DRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
+ V G G FGE AL R A+V A A +DR +F+ ++
Sbjct: 289 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLI 340
>AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 73.3 bits (172), Expect = 5e-13
Identities = 45/155 (29%), Positives = 78/155 (50%), Gaps = 1/155 (0%)
Frame = +2
Query: 47 RRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM 226
+R+++ AE + D +PKS + + EA+ ++L+ Q+Q+++D M
Sbjct: 75 KRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCM 134
Query: 227 FEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMY 403
+ +I++GD G YV+E+G +V G V G G FGELA++Y
Sbjct: 135 YPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILY 188
Query: 404 NMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKK 508
N R A+V+ LWA+DR F+ I++++ K
Sbjct: 189 NCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIK 223
Score = 60.9 bits (141), Expect = 3e-09
Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 1/112 (0%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
E ++ + F+SL + + ++ D + E E GEY+IRQG GD F++I G +V
Sbjct: 229 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 288
Query: 335 DRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
+ V G G FGE AL R A+V A A +DR +F+ ++
Sbjct: 289 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLI 340
>Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 70.5 bits (165), Expect = 3e-12
Identities = 41/131 (31%), Positives = 69/131 (52%), Gaps = 1/131 (0%)
Frame = +2
Query: 119 FPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVI 298
F KS+ + + EA+ ++L+ Q+Q+++D M+ +I++GD G YV+
Sbjct: 84 FTKSERSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVM 143
Query: 299 ENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTF 475
E+G +V G V G G FGELA++YN R A+V+ LWA+DR F
Sbjct: 144 EDGKVEVTKEG------VKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCF 197
Query: 476 RRILLKSAFKK 508
+ I++++ K
Sbjct: 198 QTIMMRTGLIK 208
Score = 60.9 bits (141), Expect = 3e-09
Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 1/112 (0%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
E ++ + F+SL + + ++ D + E E GEY+IRQG GD F++I G +V
Sbjct: 214 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 273
Query: 335 DRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
+ V G G FGE AL R A+V A A +DR +F+ ++
Sbjct: 274 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLI 325
>D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 70.5 bits (165), Expect = 3e-12
Identities = 41/131 (31%), Positives = 69/131 (52%), Gaps = 1/131 (0%)
Frame = +2
Query: 119 FPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVI 298
F KS+ + + EA+ ++L+ Q+Q+++D M+ +I++GD G YV+
Sbjct: 84 FTKSERSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVM 143
Query: 299 ENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTF 475
E+G +V G V G G FGELA++YN R A+V+ LWA+DR F
Sbjct: 144 EDGKVEVTKEG------VKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCF 197
Query: 476 RRILLKSAFKK 508
+ I++++ K
Sbjct: 198 QTIMMRTGLIK 208
Score = 60.9 bits (141), Expect = 3e-09
Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 1/112 (0%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
E ++ + F+SL + + ++ D + E E GEY+IRQG GD F++I G +V
Sbjct: 214 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 273
Query: 335 DRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
+ V G G FGE AL R A+V A A +DR +F+ ++
Sbjct: 274 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLI 325
>AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 70.5 bits (165), Expect = 3e-12
Identities = 41/131 (31%), Positives = 69/131 (52%), Gaps = 1/131 (0%)
Frame = +2
Query: 119 FPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVI 298
F KS+ + + EA+ ++L+ Q+Q+++D M+ +I++GD G YV+
Sbjct: 72 FTKSERSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVM 131
Query: 299 ENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTF 475
E+G +V G V G G FGELA++YN R A+V+ LWA+DR F
Sbjct: 132 EDGKVEVTKEG------VKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCF 185
Query: 476 RRILLKSAFKK 508
+ I++++ K
Sbjct: 186 QTIMMRTGLIK 196
Score = 60.9 bits (141), Expect = 3e-09
Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 1/112 (0%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
E ++ + F+SL + + ++ D + E E GEY+IRQG GD F++I G +V
Sbjct: 202 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 261
Query: 335 DRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
+ V G G FGE AL R A+V A A +DR +F+ ++
Sbjct: 262 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLI 313
>AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 70.5 bits (165), Expect = 3e-12
Identities = 41/131 (31%), Positives = 69/131 (52%), Gaps = 1/131 (0%)
Frame = +2
Query: 119 FPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVI 298
F KS+ + + EA+ ++L+ Q+Q+++D M+ +I++GD G YV+
Sbjct: 72 FTKSERSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVM 131
Query: 299 ENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTF 475
E+G +V G V G G FGELA++YN R A+V+ LWA+DR F
Sbjct: 132 EDGKVEVTKEG------VKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCF 185
Query: 476 RRILLKSAFKK 508
+ I++++ K
Sbjct: 186 QTIMMRTGLIK 196
Score = 60.9 bits (141), Expect = 3e-09
Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 1/112 (0%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
E ++ + F+SL + + ++ D + E E GEY+IRQG GD F++I G +V
Sbjct: 202 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 261
Query: 335 DRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
+ V G G FGE AL R A+V A A +DR +F+ ++
Sbjct: 262 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLI 313
>AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 70.5 bits (165), Expect = 3e-12
Identities = 41/131 (31%), Positives = 69/131 (52%), Gaps = 1/131 (0%)
Frame = +2
Query: 119 FPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVI 298
F KS+ + + EA+ ++L+ Q+Q+++D M+ +I++GD G YV+
Sbjct: 72 FTKSERSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVM 131
Query: 299 ENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTF 475
E+G +V G V G G FGELA++YN R A+V+ LWA+DR F
Sbjct: 132 EDGKVEVTKEG------VKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCF 185
Query: 476 RRILLKSAFKK 508
+ I++++ K
Sbjct: 186 QTIMMRTGLIK 196
Score = 60.9 bits (141), Expect = 3e-09
Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 1/112 (0%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
E ++ + F+SL + + ++ D + E E GEY+IRQG GD F++I G +V
Sbjct: 202 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 261
Query: 335 DRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
+ V G G FGE AL R A+V A A +DR +F+ ++
Sbjct: 262 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLI 313
>AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 70.5 bits (165), Expect = 3e-12
Identities = 41/131 (31%), Positives = 69/131 (52%), Gaps = 1/131 (0%)
Frame = +2
Query: 119 FPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVI 298
F KS+ + + EA+ ++L+ Q+Q+++D M+ +I++GD G YV+
Sbjct: 72 FTKSERSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVM 131
Query: 299 ENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTF 475
E+G +V G V G G FGELA++YN R A+V+ LWA+DR F
Sbjct: 132 EDGKVEVTKEG------VKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCF 185
Query: 476 RRILLKSAFKK 508
+ I++++ K
Sbjct: 186 QTIMMRTGLIK 196
Score = 60.9 bits (141), Expect = 3e-09
Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 1/112 (0%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
E ++ + F+SL + + ++ D + E E GEY+IRQG GD F++I G +V
Sbjct: 202 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 261
Query: 335 DRVEKVVHTYEGSGS-FGELALMYNMPRAASVRAQTAGALWAMDRHTFRRIL 487
+ V G G FGE AL R A+V A A +DR +F+ ++
Sbjct: 262 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLI 313
>EF157730-1|ABO15447.1| 35|Homo sapiens type II cAMP-dependent
regulatory protein kinase beta protein.
Length = 35
Score = 58.4 bits (135), Expect = 1e-08
Identities = 26/35 (74%), Positives = 30/35 (85%)
Frame = +2
Query: 197 QQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIE 301
+QM QVLDAMFEK + GE+VI QGDDGDNFYVI+
Sbjct: 1 EQMSQVLDAMFEKLVKDGEHVIDQGDDGDNFYVID 35
>AJ238850-1|CAB52754.1| 1203|Homo sapiens
hyperpolarization-activated channel type 4 protein.
Length = 1203
Score = 57.2 bits (132), Expect = 3e-08
Identities = 35/117 (29%), Positives = 58/117 (49%)
Frame = +2
Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
V + LF + D + +L + + +PG+Y+IR+G G Y I++GV VL G+
Sbjct: 590 VASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKE 649
Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511
+ +Y FGE+ L+ R ASVRA T L+++ F +L + +R
Sbjct: 650 TKLADGSY-----FGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRR 701
>AJ132429-1|CAB42604.1| 1203|Homo sapiens
hyperpolarization-activated cyclic nucleotide gated
cation channel hHCN4 protein.
Length = 1203
Score = 57.2 bits (132), Expect = 3e-08
Identities = 35/117 (29%), Positives = 58/117 (49%)
Frame = +2
Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
V + LF + D + +L + + +PG+Y+IR+G G Y I++GV VL G+
Sbjct: 590 VASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKE 649
Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511
+ +Y FGE+ L+ R ASVRA T L+++ F +L + +R
Sbjct: 650 TKLADGSY-----FGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRR 701
>AJ133727-1|CAB42630.1| 889|Homo sapiens
hyperpolarization-activated cyclic nucleotide-gated
channel hHCN2 protein.
Length = 889
Score = 56.8 bits (131), Expect = 4e-08
Identities = 37/117 (31%), Positives = 60/117 (51%)
Frame = +2
Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
V + LF + D + +L + + +PG+Y+IR+G G Y I++GV VL G+
Sbjct: 539 VASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGN-- 596
Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511
K + +GS FGE+ L+ R ASVRA T L+++ F +L + +R
Sbjct: 597 --KEMKLSDGS-YFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRR 650
>AJ012582-1|CAB42602.1| 889|Homo sapiens
hyperpolarization-activated cation channel HCN2 protein.
Length = 889
Score = 56.8 bits (131), Expect = 4e-08
Identities = 37/117 (31%), Positives = 60/117 (51%)
Frame = +2
Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
V + LF + D + +L + + +PG+Y+IR+G G Y I++GV VL G+
Sbjct: 539 VASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGN-- 596
Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511
K + +GS FGE+ L+ R ASVRA T L+++ F +L + +R
Sbjct: 597 --KEMKLSDGS-YFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRR 650
>AF065164-1|AAC28444.2| 889|Homo sapiens
hyperpolarization-activated, cyclic nucleotide-gated
channel 2 protein.
Length = 889
Score = 56.8 bits (131), Expect = 4e-08
Identities = 37/117 (31%), Positives = 60/117 (51%)
Frame = +2
Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
V + LF + D + +L + + +PG+Y+IR+G G Y I++GV VL G+
Sbjct: 539 VASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGN-- 596
Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511
K + +GS FGE+ L+ R ASVRA T L+++ F +L + +R
Sbjct: 597 --KEMKLSDGS-YFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRR 650
>AF064877-1|AAC39760.1| 597|Homo sapiens ion channel BCNG-2
protein.
Length = 597
Score = 56.8 bits (131), Expect = 4e-08
Identities = 37/117 (31%), Positives = 60/117 (51%)
Frame = +2
Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
V + LF + D + +L + + +PG+Y+IR+G G Y I++GV VL G+
Sbjct: 393 VASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGN-- 450
Query: 341 VEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511
K + +GS FGE+ L+ R ASVRA T L+++ F +L + +R
Sbjct: 451 --KEMKLSDGS-YFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRR 504
>AL391378-3|CAI39627.1| 181|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 181
Score = 52.8 bits (121), Expect = 7e-07
Identities = 31/85 (36%), Positives = 47/85 (55%), Gaps = 1/85 (1%)
Frame = +2
Query: 257 VIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPRAASVRA 433
+I++GD G YV+E+G +V G V G G FGELA++YN R A+V+
Sbjct: 3 IIKEGDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILYNCTRTATVKT 56
Query: 434 QTAGALWAMDRHTFRRILLKSAFKK 508
LWA+DR F+ I++++ K
Sbjct: 57 LVNVKLWAIDRQCFQTIMMRTGLIK 81
Score = 50.0 bits (114), Expect = 5e-06
Identities = 28/82 (34%), Positives = 42/82 (51%), Gaps = 1/82 (1%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
E ++ + F+SL + + ++ D + E E GEY+IRQG GD F++I G +V
Sbjct: 87 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 146
Query: 335 DRVEKVVHTYEGSGS-FGELAL 397
+ V G G FGE AL
Sbjct: 147 PSEDPVFLRTLGKGDWFGEKAL 168
>AL157399-3|CAI41306.1| 181|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 181
Score = 52.8 bits (121), Expect = 7e-07
Identities = 31/85 (36%), Positives = 47/85 (55%), Gaps = 1/85 (1%)
Frame = +2
Query: 257 VIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPRAASVRA 433
+I++GD G YV+E+G +V G V G G FGELA++YN R A+V+
Sbjct: 3 IIKEGDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILYNCTRTATVKT 56
Query: 434 QTAGALWAMDRHTFRRILLKSAFKK 508
LWA+DR F+ I++++ K
Sbjct: 57 LVNVKLWAIDRQCFQTIMMRTGLIK 81
Score = 50.0 bits (114), Expect = 5e-06
Identities = 28/82 (34%), Positives = 42/82 (51%), Gaps = 1/82 (1%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
E ++ + F+SL + + ++ D + E E GEY+IRQG GD F++I G +V
Sbjct: 87 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 146
Query: 335 DRVEKVVHTYEGSGS-FGELAL 397
+ V G G FGE AL
Sbjct: 147 PSEDPVFLRTLGKGDWFGEKAL 168
>AF064876-1|AAC39759.1| 749|Homo sapiens ion channel BCNG-1
protein.
Length = 749
Score = 52.4 bits (120), Expect = 9e-07
Identities = 34/112 (30%), Positives = 57/112 (50%)
Frame = +2
Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
LF + D + +L + + +PG+Y+IR+G G Y I++GV V+ + K +
Sbjct: 354 LFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVIT----KSSKEM 409
Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511
+GS FGE+ L+ R ASVRA T L+++ F +L + +R
Sbjct: 410 KLTDGS-YFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRR 460
>AF488549-1|AAO49469.1| 890|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel
protein.
Length = 890
Score = 50.0 bits (114), Expect = 5e-06
Identities = 31/103 (30%), Positives = 53/103 (51%)
Frame = +2
Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
LF + D + +L + + +PG+Y++R+G G Y I++GV V+ + K +
Sbjct: 475 LFANADPNFVTAMLSKLRFEVFQPGDYIVREGAVGKKMYFIQHGVAGVIT----KSSKEM 530
Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484
+GS FGE+ L+ R ASVRA T L+++ F +
Sbjct: 531 KLTDGS-YFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEV 572
>U78516-1|AAD03422.1| 1011|Homo sapiens cAMP-regulated guanine
nucleotide exchange factor II protein.
Length = 1011
Score = 49.2 bits (112), Expect = 8e-06
Identities = 29/89 (32%), Positives = 49/89 (55%), Gaps = 1/89 (1%)
Frame = +2
Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403
+FE ++ G + QG++G ++Y+I G +V++ G + VV T FG+LAL+
Sbjct: 373 IFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYG----KGVVCTLHEGDDFGKLALVN 428
Query: 404 NMPRAASVRAQTAGA-LWAMDRHTFRRIL 487
+ PRAAS+ + +D+ F RIL
Sbjct: 429 DAPRAASIVLREDNCHFLRVDKEDFNRIL 457
Score = 38.7 bits (86), Expect = 0.012
Identities = 26/110 (23%), Positives = 51/110 (46%), Gaps = 2/110 (1%)
Frame = +2
Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV--TGD 334
++ + F + Q+ + + E G + RQGD G N+Y + G DV V T
Sbjct: 38 LKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSS 97
Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484
+ + T +FGE +++ N PR A++ + + L +++ F+ +
Sbjct: 98 HQDAVTICTLGIGTAFGE-SILDNTPRHATIVTRESSELLRIEQKDFKAL 146
>BC040183-1|AAH40183.1| 867|Homo sapiens RAPGEF4 protein protein.
Length = 867
Score = 49.2 bits (112), Expect = 8e-06
Identities = 29/89 (32%), Positives = 49/89 (55%), Gaps = 1/89 (1%)
Frame = +2
Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403
+FE ++ G + QG++G ++Y+I G +V++ G + VV T FG+LAL+
Sbjct: 229 IFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYG----KGVVCTLHEGDDFGKLALVN 284
Query: 404 NMPRAASVRAQTAGA-LWAMDRHTFRRIL 487
+ PRAAS+ + +D+ F RIL
Sbjct: 285 DAPRAASIVLREDNCHFLRVDKEDFNRIL 313
>BC028024-1|AAH28024.2| 450|Homo sapiens HCN3 protein protein.
Length = 450
Score = 49.2 bits (112), Expect = 8e-06
Identities = 34/112 (30%), Positives = 54/112 (48%)
Frame = +2
Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
LF D + VL + + +PG+ V+R+G G Y I++G+ VL G +
Sbjct: 104 LFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLARG----ARDT 159
Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511
+GS FGE+ L+ R ASVRA T L+++ F +L + +R
Sbjct: 160 RLTDGS-YFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRR 210
>BC024004-1|AAH24004.1| 1011|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 4 protein.
Length = 1011
Score = 49.2 bits (112), Expect = 8e-06
Identities = 29/89 (32%), Positives = 49/89 (55%), Gaps = 1/89 (1%)
Frame = +2
Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403
+FE ++ G + QG++G ++Y+I G +V++ G + VV T FG+LAL+
Sbjct: 373 IFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYG----KGVVCTLHEGDDFGKLALVN 428
Query: 404 NMPRAASVRAQTAGA-LWAMDRHTFRRIL 487
+ PRAAS+ + +D+ F RIL
Sbjct: 429 DAPRAASIVLREDNCHFLRVDKEDFNRIL 457
Score = 38.7 bits (86), Expect = 0.012
Identities = 26/110 (23%), Positives = 51/110 (46%), Gaps = 2/110 (1%)
Frame = +2
Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV--TGD 334
++ + F + Q+ + + E G + RQGD G N+Y + G DV V T
Sbjct: 38 LKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSS 97
Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484
+ + T +FGE +++ N PR A++ + + L +++ F+ +
Sbjct: 98 HQDAVTICTLGIGTAFGE-SILDNTPRHATIVTRESSELLRIEQKDFKAL 146
>BC000066-1|AAH00066.1| 571|Homo sapiens Unknown (protein for
IMAGE:3507934) protein.
Length = 571
Score = 49.2 bits (112), Expect = 8e-06
Identities = 34/112 (30%), Positives = 54/112 (48%)
Frame = +2
Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
LF D + VL + + +PG+ V+R+G G Y I++G+ VL G +
Sbjct: 225 LFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLARG----ARDT 280
Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511
+GS FGE+ L+ R ASVRA T L+++ F +L + +R
Sbjct: 281 RLTDGS-YFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRR 331
>AL713999-31|CAI95100.1| 774|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel 3
protein.
Length = 774
Score = 49.2 bits (112), Expect = 8e-06
Identities = 34/112 (30%), Positives = 54/112 (48%)
Frame = +2
Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
LF D + VL + + +PG+ V+R+G G Y I++G+ VL G +
Sbjct: 428 LFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLARG----ARDT 483
Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511
+GS FGE+ L+ R ASVRA T L+++ F +L + +R
Sbjct: 484 RLTDGS-YFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRR 534
>AF488550-1|AAO49470.1| 774|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel
protein.
Length = 774
Score = 49.2 bits (112), Expect = 8e-06
Identities = 34/112 (30%), Positives = 54/112 (48%)
Frame = +2
Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
LF D + VL + + +PG+ V+R+G G Y I++G+ VL G +
Sbjct: 428 LFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLARG----ARDT 483
Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511
+GS FGE+ L+ R ASVRA T L+++ F +L + +R
Sbjct: 484 RLTDGS-YFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRR 534
>AB040968-1|BAA96059.2| 711|Homo sapiens KIAA1535 protein protein.
Length = 711
Score = 49.2 bits (112), Expect = 8e-06
Identities = 34/112 (30%), Positives = 54/112 (48%)
Frame = +2
Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
LF D + VL + + +PG+ V+R+G G Y I++G+ VL G +
Sbjct: 365 LFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLARG----ARDT 420
Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILLKSAFKKR 511
+GS FGE+ L+ R ASVRA T L+++ F +L + +R
Sbjct: 421 RLTDGS-YFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRR 471
>AB027471-1|BAB72179.1| 1011|Homo sapiens cAMP-GEFII protein.
Length = 1011
Score = 49.2 bits (112), Expect = 8e-06
Identities = 29/89 (32%), Positives = 49/89 (55%), Gaps = 1/89 (1%)
Frame = +2
Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403
+FE ++ G + QG++G ++Y+I G +V++ G + VV T FG+LAL+
Sbjct: 373 IFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYG----KGVVCTLHEGDDFGKLALVN 428
Query: 404 NMPRAASVRAQTAGA-LWAMDRHTFRRIL 487
+ PRAAS+ + +D+ F RIL
Sbjct: 429 DAPRAASIVLREDNCHFLRVDKEDFNRIL 457
Score = 38.7 bits (86), Expect = 0.012
Identities = 26/110 (23%), Positives = 51/110 (46%), Gaps = 2/110 (1%)
Frame = +2
Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV--TGD 334
++ + F + Q+ + + E G + RQGD G N+Y + G DV V T
Sbjct: 38 LKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSS 97
Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484
+ + T +FGE +++ N PR A++ + + L +++ F+ +
Sbjct: 98 HQDAVTICTLGIGTAFGE-SILDNTPRHATIVTRESSELLRIEQKDFKAL 146
>AF272900-1|AAF86274.1| 809|Homo sapiens cone photoreceptor cyclic
nucleotide-gated channel beta subunit protein.
Length = 809
Score = 48.4 bits (110), Expect = 1e-05
Identities = 32/108 (29%), Positives = 55/108 (50%), Gaps = 3/108 (2%)
Frame = +2
Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
LF+ D Q + +L + PG++V ++G+ G Y+I++G +V V G KV+
Sbjct: 524 LFKGCDTQMIYDMLLRLKSVLYLPGDFVCKKGEIGKEMYIIKHG--EVQVLGGPDGTKVL 581
Query: 356 HTYEGSGSFGELALMY---NMPRAASVRAQTAGALWAMDRHTFRRILL 490
T + FGE++L+ R A+V A L +D+ T + IL+
Sbjct: 582 VTLKAGSVFGEISLLAAGGGNRRTANVVAHGFANLLTLDKKTLQEILV 629
>U78169-1|AAD02890.1| 556|Homo sapiens cAMP-regulated guanine
nucleotide exchange factor I protein.
Length = 556
Score = 47.2 bits (107), Expect = 3e-05
Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
Frame = +2
Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403
+FE S+ G + QGD G ++Y+I G +V+ G + +V T FG+LAL+
Sbjct: 220 LFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHG----KGLVTTLHEGDDFGQLALVN 275
Query: 404 NMPRAASVRAQTAGA-LWAMDRHTFRRIL 487
+ PRAA++ + +D+ F RI+
Sbjct: 276 DAPRAATIILREYNCHFLRVDKQDFNRII 304
>U78168-1|AAD12740.1| 881|Homo sapiens cAMP-regulated guanine
nucleotide exchange factor I protein.
Length = 881
Score = 47.2 bits (107), Expect = 3e-05
Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
Frame = +2
Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403
+FE S+ G + QGD G ++Y+I G +V+ G + +V T FG+LAL+
Sbjct: 220 LFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHG----KGLVTTLHEGDDFGQLALVN 275
Query: 404 NMPRAASVRAQTAGA-LWAMDRHTFRRIL 487
+ PRAA++ + +D+ F RI+
Sbjct: 276 DAPRAATIILREYNCHFLRVDKQDFNRII 304
>BC092404-1|AAH92404.1| 881|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 3 protein.
Length = 881
Score = 47.2 bits (107), Expect = 3e-05
Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
Frame = +2
Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403
+FE S+ G + QGD G ++Y+I G +V+ G + +V T FG+LAL+
Sbjct: 220 LFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHG----KGLVTTLHEGDDFGQLALVN 275
Query: 404 NMPRAASVRAQTAGA-LWAMDRHTFRRIL 487
+ PRAA++ + +D+ F RI+
Sbjct: 276 DAPRAATIILREDNCHFLRVDKQDFNRII 304
>BC068477-1|AAH68477.1| 343|Homo sapiens RAPGEF3 protein protein.
Length = 343
Score = 47.2 bits (107), Expect = 3e-05
Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
Frame = +2
Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403
+FE S+ G + QGD G ++Y+I G +V+ G + +V T FG+LAL+
Sbjct: 220 LFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHG----KGLVTTLHEGDDFGQLALVN 275
Query: 404 NMPRAASVRAQTAGA-LWAMDRHTFRRIL 487
+ PRAA++ + +D+ F RI+
Sbjct: 276 DAPRAATIILREDNCHFLRVDKQDFNRII 304
>BC040534-1|AAH40534.1| 321|Homo sapiens RAPGEF3 protein protein.
Length = 321
Score = 47.2 bits (107), Expect = 3e-05
Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
Frame = +2
Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403
+FE S+ G + QGD G ++Y+I G +V+ G + +V T FG+LAL+
Sbjct: 220 LFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHG----KGLVTTLHEGDDFGQLALVN 275
Query: 404 NMPRAASVRAQTAGA-LWAMDRHTFRRIL 487
+ PRAA++ + +D+ F RI+
Sbjct: 276 DAPRAATIILREDNCHFLRVDKQDFNRII 304
>BC017728-1|AAH17728.1| 881|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 3 protein.
Length = 881
Score = 47.2 bits (107), Expect = 3e-05
Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
Frame = +2
Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403
+FE S+ G + QGD G ++Y+I G +V+ G + +V T FG+LAL+
Sbjct: 220 LFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHG----KGLVTTLHEGDDFGQLALVN 275
Query: 404 NMPRAASVRAQTAGA-LWAMDRHTFRRIL 487
+ PRAA++ + +D+ F RI+
Sbjct: 276 DAPRAATIILREDNCHFLRVDKQDFNRII 304
>AF103905-1|AAC83381.1| 881|Homo sapiens Rap1 guanine-nucleotide
exchange factor protein.
Length = 881
Score = 47.2 bits (107), Expect = 3e-05
Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
Frame = +2
Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403
+FE S+ G + QGD G ++Y+I G +V+ G + +V T FG+LAL+
Sbjct: 220 LFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHG----KGLVTTLHEGDDFGQLALVN 275
Query: 404 NMPRAASVRAQTAGA-LWAMDRHTFRRIL 487
+ PRAA++ + +D+ F RI+
Sbjct: 276 DAPRAATIILREDNCHFLRVDKQDFNRII 304
>AB209681-1|BAD92918.1| 643|Homo sapiens RAP
guanine-nucleotide-exchange factor 4 variant protein.
Length = 643
Score = 44.0 bits (99), Expect = 3e-04
Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 1/78 (1%)
Frame = +2
Query: 257 VIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQ 436
V QG++G ++Y+I G +V++ G + VV T FG+LAL+ + PRAAS+ +
Sbjct: 16 VFNQGEEGTSWYIILKGSVNVVIYG----KGVVCTLHEGDDFGKLALVNDAPRAASIVLR 71
Query: 437 TAGA-LWAMDRHTFRRIL 487
+D+ F RIL
Sbjct: 72 EDNCHFLRVDKEDFNRIL 89
>AC004492-1|AAC08318.1| 112|Homo sapiens CAMP-DEPENDENT PROTEIN
KINASE TYPE II-BETA REGULATORY CHAIN protein.
Length = 112
Score = 43.6 bits (98), Expect = 4e-04
Identities = 29/80 (36%), Positives = 40/80 (50%), Gaps = 7/80 (8%)
Frame = +2
Query: 269 GDDGDNFYVIENGVFDVLVT--GDDRVEK-----VVHTYEGSGSFGELALMYNMPRAASV 427
GD D+F+++E+G + + G VE+ + G FGELAL+ N PRAAS
Sbjct: 1 GDSADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCSRGQ-YFGELALVTNKPRAASA 59
Query: 428 RAQTAGALWAMDRHTFRRIL 487
A AMD F R+L
Sbjct: 60 HAIGTVKCLAMDVQAFERLL 79
>U58837-1|AAB63387.1| 1251|Homo sapiens cGMP-gated cation channel beta
subunit protein.
Length = 1251
Score = 41.9 bits (94), Expect = 0.001
Identities = 31/113 (27%), Positives = 53/113 (46%), Gaps = 3/113 (2%)
Frame = +2
Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
V + LF+ D Q + +L + P +YV ++G+ G Y+I+ G V V G
Sbjct: 957 VSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAG--QVQVLGGPD 1014
Query: 341 VEKVVHTYEGSGSFGELALMY---NMPRAASVRAQTAGALWAMDRHTFRRILL 490
+ V+ T + FGE++L+ R A+V A L+ +D+ IL+
Sbjct: 1015 GKSVLVTLKAGSVFGEISLLAVGGGNRRTANVVAHGFTNLFILDKKDLNEILV 1067
>L15297-1|AAA65619.1| 623|Homo sapiens cyclic nucleotide-gated
cation channel protein.
Length = 623
Score = 41.9 bits (94), Expect = 0.001
Identities = 31/113 (27%), Positives = 53/113 (46%), Gaps = 3/113 (2%)
Frame = +2
Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
V + LF+ D Q + +L + P +YV ++G+ G Y+I+ G V V G
Sbjct: 329 VSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAG--QVQVLGGPD 386
Query: 341 VEKVVHTYEGSGSFGELALMY---NMPRAASVRAQTAGALWAMDRHTFRRILL 490
+ V+ T + FGE++L+ R A+V A L+ +D+ IL+
Sbjct: 387 GKSVLVTLKAGSVFGEISLLAVGGGNRRTANVVAHGFTNLFILDKKDLNEILV 439
>L15296-1|AAA65620.1| 909|Homo sapiens cyclic nucleotide-gated
cation channel protein.
Length = 909
Score = 41.9 bits (94), Expect = 0.001
Identities = 31/113 (27%), Positives = 53/113 (46%), Gaps = 3/113 (2%)
Frame = +2
Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
V + LF+ D Q + +L + P +YV ++G+ G Y+I+ G V V G
Sbjct: 615 VSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAG--QVQVLGGPD 672
Query: 341 VEKVVHTYEGSGSFGELALMY---NMPRAASVRAQTAGALWAMDRHTFRRILL 490
+ V+ T + FGE++L+ R A+V A L+ +D+ IL+
Sbjct: 673 GKSVLVTLKAGSVFGEISLLAVGGGNRRTANVVAHGFTNLFILDKKDLNEILV 725
>BC040277-1|AAH40277.1| 474|Homo sapiens CNGA4 protein protein.
Length = 474
Score = 41.9 bits (94), Expect = 0.001
Identities = 22/78 (28%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Frame = +2
Query: 170 ILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEK 349
+ +F++ +A +++++ + + PGEYV R+GD G Y+I G + V DD + +
Sbjct: 364 VQIFQNCEASLLEELVLKLQPQTYSPGEYVCRKGDIGQEMYIIREG--QLAVVADDGITQ 421
Query: 350 VVHTYEGSG-SFGELALM 400
+ G+G FGE++++
Sbjct: 422 --YAVLGAGLYFGEISII 437
>AF042498-1|AAC04830.1| 1245|Homo sapiens rod photoreceptor
CNG-channel beta subunit protein.
Length = 1245
Score = 41.9 bits (94), Expect = 0.001
Identities = 31/113 (27%), Positives = 53/113 (46%), Gaps = 3/113 (2%)
Frame = +2
Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
V + LF+ D Q + +L + P +YV ++G+ G Y+I+ G V V G
Sbjct: 951 VSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAG--QVQVLGGPD 1008
Query: 341 VEKVVHTYEGSGSFGELALMY---NMPRAASVRAQTAGALWAMDRHTFRRILL 490
+ V+ T + FGE++L+ R A+V A L+ +D+ IL+
Sbjct: 1009 GKSVLVTLKAGSVFGEISLLAVGGGNRRTANVVAHGFTNLFILDKKDLNEILV 1061
>S76069-1|AAD14208.1| 261|Homo sapiens CNG3 protein.
Length = 261
Score = 41.5 bits (93), Expect = 0.002
Identities = 25/96 (26%), Positives = 52/96 (54%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
+ ++ + +F+ +A + +++ + PG+Y+ ++GD G Y+I G + V D
Sbjct: 156 DTLKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYIINEG--KLAVVAD 213
Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTA 442
D V + V +GS FGE++++ N+ + S +TA
Sbjct: 214 DGVTQFVVLSDGS-YFGEISIL-NIKGSKSGNRRTA 247
>M84741-1|AAA52010.1| 690|Homo sapiens cGMP-gated cation channel
protein protein.
Length = 690
Score = 41.5 bits (93), Expect = 0.002
Identities = 21/82 (25%), Positives = 47/82 (57%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
+ ++ + +F +A + +++ + + PG+Y+ ++GD G Y+I+ G + V D
Sbjct: 472 DTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEG--KLAVVAD 529
Query: 335 DRVEKVVHTYEGSGSFGELALM 400
D V + V +GS +FGE++++
Sbjct: 530 DGVTQFVVLSDGS-TFGEISIL 550
>BC096300-1|AAH96300.1| 694|Homo sapiens cyclic nucleotide gated
channel alpha 3 protein.
Length = 694
Score = 41.5 bits (93), Expect = 0.002
Identities = 25/96 (26%), Positives = 52/96 (54%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
+ ++ + +F+ +A + +++ + PG+Y+ ++GD G Y+I G + V D
Sbjct: 475 DTLKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYIINEG--KLAVVAD 532
Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTA 442
D V + V +GS FGE++++ N+ + S +TA
Sbjct: 533 DGVTQFVVLSDGS-YFGEISIL-NIKGSKSGNRRTA 566
>BC096299-1|AAH96299.1| 676|Homo sapiens cyclic nucleotide gated
channel alpha 3 protein.
Length = 676
Score = 41.5 bits (93), Expect = 0.002
Identities = 25/96 (26%), Positives = 52/96 (54%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
+ ++ + +F+ +A + +++ + PG+Y+ ++GD G Y+I G + V D
Sbjct: 457 DTLKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYIINEG--KLAVVAD 514
Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTA 442
D V + V +GS FGE++++ N+ + S +TA
Sbjct: 515 DGVTQFVVLSDGS-YFGEISIL-NIKGSKSGNRRTA 548
>BC096298-1|AAH96298.1| 694|Homo sapiens cyclic nucleotide gated
channel alpha 3 protein.
Length = 694
Score = 41.5 bits (93), Expect = 0.002
Identities = 25/96 (26%), Positives = 52/96 (54%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
+ ++ + +F+ +A + +++ + PG+Y+ ++GD G Y+I G + V D
Sbjct: 475 DTLKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYIINEG--KLAVVAD 532
Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTA 442
D V + V +GS FGE++++ N+ + S +TA
Sbjct: 533 DGVTQFVVLSDGS-YFGEISIL-NIKGSKSGNRRTA 566
>AK131300-1|BAD18468.1| 698|Homo sapiens mRNA. protein.
Length = 698
Score = 41.5 bits (93), Expect = 0.002
Identities = 25/96 (26%), Positives = 52/96 (54%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
+ ++ + +F+ +A + +++ + PG+Y+ ++GD G Y+I G + V D
Sbjct: 479 DTLKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYIINEG--KLAVVAD 536
Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTA 442
D V + V +GS FGE++++ N+ + S +TA
Sbjct: 537 DGVTQFVVLSDGS-YFGEISIL-NIKGSKSGNRRTA 570
>AF065314-1|AAC17440.1| 694|Homo sapiens cone photoreceptor
cGMP-gated channel alpha subunit protein.
Length = 694
Score = 41.5 bits (93), Expect = 0.002
Identities = 25/96 (26%), Positives = 52/96 (54%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
+ ++ + +F+ +A + +++ + PG+Y+ ++GD G Y+I G + V D
Sbjct: 475 DTLKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYIINEG--KLAVVAD 532
Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTA 442
D V + V +GS FGE++++ N+ + S +TA
Sbjct: 533 DGVTQFVVLSDGS-YFGEISIL-NIKGSKSGNRRTA 566
>AC092675-2|AAY24181.1| 694|Homo sapiens unknown protein.
Length = 694
Score = 41.5 bits (93), Expect = 0.002
Identities = 25/96 (26%), Positives = 52/96 (54%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
+ ++ + +F+ +A + +++ + PG+Y+ ++GD G Y+I G + V D
Sbjct: 475 DTLKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYIINEG--KLAVVAD 532
Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTA 442
D V + V +GS FGE++++ N+ + S +TA
Sbjct: 533 DGVTQFVVLSDGS-YFGEISIL-NIKGSKSGNRRTA 566
>S76062-1|AAD14206.1| 261|Homo sapiens CNG1 protein.
Length = 261
Score = 40.3 bits (90), Expect = 0.004
Identities = 21/82 (25%), Positives = 46/82 (56%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
+ ++ + +F +A + +++ + + PG+Y+ ++GD G Y+I+ G + V D
Sbjct: 156 DTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEG--KLAVVAD 213
Query: 335 DRVEKVVHTYEGSGSFGELALM 400
D V + V +GS FGE++++
Sbjct: 214 DGVTQFVVLSDGS-YFGEISIL 234
>S42457-1|AAB22778.1| 686|Homo sapiens rod photoreceptor cGMP-gated
channel protein.
Length = 686
Score = 40.3 bits (90), Expect = 0.004
Identities = 21/82 (25%), Positives = 46/82 (56%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
+ ++ + +F +A + +++ + + PG+Y+ ++GD G Y+I+ G + V D
Sbjct: 468 DTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEG--KLAVVAD 525
Query: 335 DRVEKVVHTYEGSGSFGELALM 400
D V + V +GS FGE++++
Sbjct: 526 DGVTQFVVLSDGS-YFGEISIL 546
>AC107068-3|AAY40919.1| 690|Homo sapiens unknown protein.
Length = 690
Score = 40.3 bits (90), Expect = 0.004
Identities = 21/82 (25%), Positives = 46/82 (56%)
Frame = +2
Query: 155 EAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGD 334
+ ++ + +F +A + +++ + + PG+Y+ ++GD G Y+I+ G + V D
Sbjct: 472 DTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEG--KLAVVAD 529
Query: 335 DRVEKVVHTYEGSGSFGELALM 400
D V + V +GS FGE++++
Sbjct: 530 DGVTQFVVLSDGS-YFGEISIL 550
>AF228520-1|AAF80179.1| 610|Homo sapiens cone photoreceptor
cGMP-gated cation channel beta-subunit protein.
Length = 610
Score = 39.9 bits (89), Expect = 0.005
Identities = 32/105 (30%), Positives = 53/105 (50%)
Frame = +2
Query: 176 LFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVV 355
LF+ D Q + +L + PG++V ++G+ G Y+I++G +V V G KV+
Sbjct: 330 LFKGCDTQMIYDMLLRLKSVLYLPGDFVCKKGEIGKEMYIIKHG--EVQVLGGPDGTKVL 387
Query: 356 HTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRILL 490
T + +GS LA R A+V A L +D+ T + IL+
Sbjct: 388 VTLK-AGSV-LLAAGGGNRRTANVVAHGFANLLTLDKKTLQEILV 430
>S76067-1|AAD14207.1| 261|Homo sapiens CNG2 protein.
Length = 261
Score = 39.1 bits (87), Expect = 0.009
Identities = 21/80 (26%), Positives = 43/80 (53%)
Frame = +2
Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
++ + +F +A + +++ + + PG+Y+ R+GD G Y+I+ G + V DD
Sbjct: 158 LKKVRIFHDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEG--KLAVVADDG 215
Query: 341 VEKVVHTYEGSGSFGELALM 400
V + GS FGE++++
Sbjct: 216 VTQYALLSAGS-CFGEISIL 234
>BC126304-1|AAI26305.1| 664|Homo sapiens cyclic nucleotide gated
channel alpha 2 protein.
Length = 664
Score = 39.1 bits (87), Expect = 0.009
Identities = 21/80 (26%), Positives = 43/80 (53%)
Frame = +2
Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
++ + +F +A + +++ + + PG+Y+ R+GD G Y+I+ G + V DD
Sbjct: 449 LKKVRIFHDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEG--KLAVVADDG 506
Query: 341 VEKVVHTYEGSGSFGELALM 400
V + GS FGE++++
Sbjct: 507 VTQYALLSAGS-CFGEISIL 525
>BC126302-1|AAI26303.1| 664|Homo sapiens cyclic nucleotide gated
channel alpha 2 protein.
Length = 664
Score = 39.1 bits (87), Expect = 0.009
Identities = 21/80 (26%), Positives = 43/80 (53%)
Frame = +2
Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDR 340
++ + +F +A + +++ + + PG+Y+ R+GD G Y+I+ G + V DD
Sbjct: 449 LKKVRIFHDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEG--KLAVVADDG 506
Query: 341 VEKVVHTYEGSGSFGELALM 400
V + GS FGE++++
Sbjct: 507 VTQYALLSAGS-CFGEISIL 525
>AC009484-1|AAY15071.1| 157|Homo sapiens unknown protein.
Length = 157
Score = 38.7 bits (86), Expect = 0.012
Identities = 26/110 (23%), Positives = 51/110 (46%), Gaps = 2/110 (1%)
Frame = +2
Query: 161 VRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLV--TGD 334
++ + F + Q+ + + E G + RQGD G N+Y + G DV V T
Sbjct: 16 LKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSS 75
Query: 335 DRVEKVVHTYEGSGSFGELALMYNMPRAASVRAQTAGALWAMDRHTFRRI 484
+ + T +FGE +++ N PR A++ + + L +++ F+ +
Sbjct: 76 HQDAVTICTLGIGTAFGE-SILDNTPRHATIVTRESSELLRIEQKDFKAL 124
>BC070478-1|AAH70478.1| 80|Homo sapiens PRKAR1B protein protein.
Length = 80
Score = 36.3 bits (80), Expect = 0.064
Identities = 17/54 (31%), Positives = 30/54 (55%)
Frame = +2
Query: 137 QRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGEYVIRQGDDGDNFYVI 298
+R E + + + SL+ + V DA+ + E GE ++ QG+ GD+FY+I
Sbjct: 7 KRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYII 60
>BC051768-1|AAH51768.1| 1327|Homo sapiens patatin-like phospholipase
domain containing 6 protein.
Length = 1327
Score = 33.5 bits (73), Expect = 0.45
Identities = 22/85 (25%), Positives = 36/85 (42%)
Frame = +2
Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403
M +R G+YV R G + YV+++G+ ++ + G D E VV S L +
Sbjct: 163 MVFQRLGQGDYVFRPGQPDASIYVVQDGLLELCLPGPDGKECVVKEVVPGDSVNSLLSIL 222
Query: 404 NMPRAASVRAQTAGALWAMDRHTFR 478
++ +T A A D R
Sbjct: 223 DVITGHQHPQRTVSARAARDSTVLR 247
Score = 33.1 bits (72), Expect = 0.59
Identities = 18/64 (28%), Positives = 29/64 (45%)
Frame = +2
Query: 242 EPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAA 421
E G + RQGD D Y++ NG ++ +++V Y G + + PRA
Sbjct: 603 EAGRALYRQGDRSDCTYIVLNGRLRSVIQRGSGKKELVGEYGRGDLIGVVEALTRQPRAT 662
Query: 422 SVRA 433
+V A
Sbjct: 663 TVHA 666
>BC050553-1|AAH50553.1| 1327|Homo sapiens patatin-like phospholipase
domain containing 6 protein.
Length = 1327
Score = 33.5 bits (73), Expect = 0.45
Identities = 22/85 (25%), Positives = 36/85 (42%)
Frame = +2
Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403
M +R G+YV R G + YV+++G+ ++ + G D E VV S L +
Sbjct: 163 MVFQRLGQGDYVFRPGQPDASIYVVQDGLLELCLPGPDGKECVVKEVVPGDSVNSLLSIL 222
Query: 404 NMPRAASVRAQTAGALWAMDRHTFR 478
++ +T A A D R
Sbjct: 223 DVITGHQHPQRTVSARAARDSTVLR 247
Score = 33.1 bits (72), Expect = 0.59
Identities = 18/64 (28%), Positives = 29/64 (45%)
Frame = +2
Query: 242 EPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAA 421
E G + RQGD D Y++ NG ++ +++V Y G + + PRA
Sbjct: 603 EAGRALYRQGDRSDCTYIVLNGRLRSVIQRGSGKKELVGEYGRGDLIGVVEALTRQPRAT 662
Query: 422 SVRA 433
+V A
Sbjct: 663 TVHA 666
>BC038229-1|AAH38229.1| 1332|Homo sapiens PNPLA6 protein protein.
Length = 1332
Score = 33.5 bits (73), Expect = 0.45
Identities = 22/85 (25%), Positives = 36/85 (42%)
Frame = +2
Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403
M +R G+YV R G + YV+++G+ ++ + G D E VV S L +
Sbjct: 169 MVFQRLGQGDYVFRPGQPDASIYVVQDGLLELCLPGPDGKECVVKEVVPGDSVNSLLSIL 228
Query: 404 NMPRAASVRAQTAGALWAMDRHTFR 478
++ +T A A D R
Sbjct: 229 DVITGHQHPQRTVSARAARDSTVLR 253
Score = 31.5 bits (68), Expect = 1.8
Identities = 17/62 (27%), Positives = 28/62 (45%)
Frame = +2
Query: 242 EPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAA 421
E G + RQGD D Y++ NG ++ +++V Y G + + PRA
Sbjct: 609 EAGRALYRQGDRSDCTYIVLNGRLRSVIQRGSGKKELVGEYGRGDLIGVVEALTRQPRAT 668
Query: 422 SV 427
+V
Sbjct: 669 TV 670
>AJ004832-1|CAA06164.1| 1327|Homo sapiens neuropathy target esterase
protein.
Length = 1327
Score = 33.5 bits (73), Expect = 0.45
Identities = 22/85 (25%), Positives = 36/85 (42%)
Frame = +2
Query: 224 MFEKRSEPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMY 403
M +R G+YV R G + YV+++G+ ++ + G D E VV S L +
Sbjct: 163 MVFQRLGQGDYVFRPGQPDASIYVVQDGLLELCLPGPDGKECVVKEVVPGDSVNSLLSIL 222
Query: 404 NMPRAASVRAQTAGALWAMDRHTFR 478
++ +T A A D R
Sbjct: 223 DVITGHQHPQRTVSARAARDSTVLR 247
Score = 33.1 bits (72), Expect = 0.59
Identities = 18/64 (28%), Positives = 29/64 (45%)
Frame = +2
Query: 242 EPGEYVIRQGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPRAA 421
E G + RQGD D Y++ NG ++ +++V Y G + + PRA
Sbjct: 603 EAGRALYRQGDRSDCTYIVLNGRLRSVIQRGSGKKELVGEYGRGDLIGVVEALTRQPRAT 662
Query: 422 SVRA 433
+V A
Sbjct: 663 TVHA 666
>BC142964-1|AAI42965.1| 827|Homo sapiens RAPGEF6 protein protein.
Length = 827
Score = 30.7 bits (66), Expect = 3.2
Identities = 16/66 (24%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
Frame = +2
Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM-FEKRSEPGEYVIRQGDDGDNFYVIE 301
K+D +L E + + F ++ +++ M FE + G ++ G + D++YVI
Sbjct: 263 KTDDDIEQLLEFMHQLPAFANMTMSVRRELCSVMIFEVVEQAGAIILEDGQELDSWYVIL 322
Query: 302 NGVFDV 319
NG ++
Sbjct: 323 NGTVEI 328
>BC133703-1|AAI33704.1| 1504|Homo sapiens RAPGEF6 protein protein.
Length = 1504
Score = 30.7 bits (66), Expect = 3.2
Identities = 16/66 (24%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
Frame = +2
Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM-FEKRSEPGEYVIRQGDDGDNFYVIE 301
K+D +L E + + F ++ +++ M FE + G ++ G + D++YVI
Sbjct: 263 KTDDDIEQLLEFMHQLPAFANMTMSVRRELCSVMIFEVVEQAGAIILEDGQELDSWYVIL 322
Query: 302 NGVFDV 319
NG ++
Sbjct: 323 NGTVEI 328
>BC036847-1|AAH36847.1| 272|Homo sapiens neurogenin 2 protein.
Length = 272
Score = 30.7 bits (66), Expect = 3.2
Identities = 18/44 (40%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
Frame = -1
Query: 393 ASSPNEPEPSYVW--TTFSTRSSPVTRTSKTPFSMT*KLSPSSP 268
+SS + P P+ W T SS V+ S +P+S T LSP+SP
Sbjct: 202 SSSGDSPSPASTWSCTNSPAPSSSVSSNSTSPYSCT--LSPASP 243
>BC011982-1|AAH11982.1| 412|Homo sapiens major facilitator
superfamily domain containing 3 protein.
Length = 412
Score = 30.7 bits (66), Expect = 3.2
Identities = 19/50 (38%), Positives = 24/50 (48%)
Frame = +2
Query: 104 GAPAVFPKSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAMFEKRSEPGE 253
G A P A +A L AV G+LL +L A LDA+ + EP E
Sbjct: 82 GLLAGLPPPGAGQAGLPAAVAGLLLLLNLGAAMQDVALDALAVQLLEPAE 131
>AF478567-1|AAM21637.1| 1601|Homo sapiens PDZ domain-containing
guanine nucleotide exchange factor PDZ-GEF2 protein.
Length = 1601
Score = 30.7 bits (66), Expect = 3.2
Identities = 16/66 (24%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
Frame = +2
Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM-FEKRSEPGEYVIRQGDDGDNFYVIE 301
K+D +L E + + F ++ +++ M FE + G ++ G + D++YVI
Sbjct: 263 KTDDDIEQLLEFMHQLPAFANMTMSVRRELCSVMIFEVVEQAGAIILEDGQELDSWYVIL 322
Query: 302 NGVFDV 319
NG ++
Sbjct: 323 NGTVEI 328
>AF478469-1|AAL79916.1| 1391|Homo sapiens Rap1 guanine
nucleotide-exchange factor PDZ-GEF2B protein.
Length = 1391
Score = 30.7 bits (66), Expect = 3.2
Identities = 16/66 (24%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
Frame = +2
Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM-FEKRSEPGEYVIRQGDDGDNFYVIE 301
K+D +L E + + F ++ +++ M FE + G ++ G + D++YVI
Sbjct: 263 KTDDDIEQLLEFMHQLPAFANMTMSVRRELCSVMIFEVVEQAGAIILEDGQELDSWYVIL 322
Query: 302 NGVFDV 319
NG ++
Sbjct: 323 NGTVEI 328
>AF478468-1|AAL79915.1| 1601|Homo sapiens Rap1 guanine
nucleotide-exchange factor PDZ-GEF2A protein.
Length = 1601
Score = 30.7 bits (66), Expect = 3.2
Identities = 16/66 (24%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
Frame = +2
Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM-FEKRSEPGEYVIRQGDDGDNFYVIE 301
K+D +L E + + F ++ +++ M FE + G ++ G + D++YVI
Sbjct: 263 KTDDDIEQLLEFMHQLPAFANMTMSVRRELCSVMIFEVVEQAGAIILEDGQELDSWYVIL 322
Query: 302 NGVFDV 319
NG ++
Sbjct: 323 NGTVEI 328
>AF414442-1|AAL65133.2|22152|Homo sapiens ovarian cancer related tumor
marker CA125 protein.
Length = 22152
Score = 30.7 bits (66), Expect = 3.2
Identities = 19/61 (31%), Positives = 32/61 (52%)
Frame = -1
Query: 393 ASSPNEPEPSYVWTTFSTRSSPVTRTSKTPFSMT*KLSPSSPCLITYSPGSDLFSNIASR 214
+ +P EPE + W T +S T S T + + + S ++P ++T SPG D S + +
Sbjct: 11567 SETPYEPETTVTWLTHPAETS--TTVSGTIPNFSHRGSDTAPSMVT-SPGVDTRSGVPTT 11623
Query: 213 T 211
T
Sbjct: 11624 T 11624
>AF394782-1|AAK83368.1| 1509|Homo sapiens rap guanine nucleotide
exchange factor protein.
Length = 1509
Score = 30.7 bits (66), Expect = 3.2
Identities = 16/66 (24%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
Frame = +2
Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM-FEKRSEPGEYVIRQGDDGDNFYVIE 301
K+D +L E + + F ++ +++ M FE + G ++ G + D++YVI
Sbjct: 263 KTDDDIEQLLEFMHQLPAFANMTMSVRRELCSVMIFEVVEQAGAIILEDGQELDSWYVIL 322
Query: 302 NGVFDV 319
NG ++
Sbjct: 323 NGTVEI 328
>AF303002-1|AAG40770.1| 250|Homo sapiens neurogenin 2 protein.
Length = 250
Score = 30.7 bits (66), Expect = 3.2
Identities = 18/44 (40%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
Frame = -1
Query: 393 ASSPNEPEPSYVW--TTFSTRSSPVTRTSKTPFSMT*KLSPSSP 268
+SS + P P+ W T SS V+ S +P+S T LSP+SP
Sbjct: 180 SSSGDSPSPASTWSCTNSPAPSSSVSSNSTSPYSCT--LSPASP 221
>AF117947-1|AAF22004.1| 1204|Homo sapiens PDZ domain-containing
guanine nucleotide exchange factor I protein.
Length = 1204
Score = 30.7 bits (66), Expect = 3.2
Identities = 16/66 (24%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
Frame = +2
Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM-FEKRSEPGEYVIRQGDDGDNFYVIE 301
K+D +L E + + F ++ +++ M FE + G ++ G + D++YVI
Sbjct: 313 KTDDDIEQLLEFMHQLPAFANMTMSVRRELCSVMIFEVVEQAGAIILEDGQELDSWYVIL 372
Query: 302 NGVFDV 319
NG ++
Sbjct: 373 NGTVEI 378
>AC004227-1|AAC04379.1| 579|Homo sapiens KIA001LB protein.
Length = 579
Score = 30.7 bits (66), Expect = 3.2
Identities = 16/66 (24%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
Frame = +2
Query: 125 KSDAQRARLAEAVRGILLFRSLDAQQMQQVLDAM-FEKRSEPGEYVIRQGDDGDNFYVIE 301
K+D +L E + + F ++ +++ M FE + G ++ G + D++YVI
Sbjct: 98 KTDDDIEQLLEFMHQLPAFANMTMSVRRELCSVMIFEVVEQAGAIILEDGQELDSWYVIL 157
Query: 302 NGVFDV 319
NG ++
Sbjct: 158 NGTVEI 163
>AB029009-1|BAA83038.1| 902|Homo sapiens KIAA1086 protein protein.
Length = 902
Score = 30.7 bits (66), Expect = 3.2
Identities = 17/56 (30%), Positives = 22/56 (39%), Gaps = 2/56 (3%)
Frame = -2
Query: 206 AFAARQENGTAVCPGPPQRDGLSVRPTWG--TRQGLLRQNHPLRGHKSRRKRICAD 45
A A R A+C GPP+ RP WG + L P +G C+D
Sbjct: 354 ALAKRPVASKALCEGPPEPQAAGCRPQWGKPAQPKLEGPGAPTQGGSKEAPAGCSD 409
>AF361486-1|AAK74120.3| 6995|Homo sapiens mucin 16 protein.
Length = 6995
Score = 30.3 bits (65), Expect = 4.2
Identities = 19/61 (31%), Positives = 32/61 (52%)
Frame = -1
Query: 393 ASSPNEPEPSYVWTTFSTRSSPVTRTSKTPFSMT*KLSPSSPCLITYSPGSDLFSNIASR 214
+ +P EPE + W T +S T S T + + + S ++P ++T SPG D S + +
Sbjct: 3271 SETPYEPETTATWLTHPAETS--TTVSGTIPNFSHRGSDTAPSMVT-SPGVDTRSGVPTT 3327
Query: 213 T 211
T
Sbjct: 3328 T 3328
>AB023164-1|BAA76791.3| 2330|Homo sapiens KIAA0947 protein protein.
Length = 2330
Score = 30.3 bits (65), Expect = 4.2
Identities = 14/33 (42%), Positives = 16/33 (48%)
Frame = -2
Query: 488 AGCDGTCGGPWPTERRRSGPVQMPPAACCTSGP 390
AG GGP R R+GP P AC +GP
Sbjct: 28 AGSGLAGGGPGGISRDRTGPTPRAPEACVPTGP 60
>Z34277-1|CAA84031.1| 477|Homo sapiens mucin protein.
Length = 477
Score = 29.9 bits (64), Expect = 5.5
Identities = 22/66 (33%), Positives = 33/66 (50%)
Frame = -1
Query: 351 TFSTRSSPVTRTSKTPFSMT*KLSPSSPCLITYSPGSDLFSNIASRTCCICCASRERNSS 172
T ST S+P T T+ TP + +S + T +P S S I++RT I A +S
Sbjct: 187 TTSTTSAPTTSTTSTPQT---SISSAPTSSTTSAPTS---STISARTTSIISAPTTSTTS 240
Query: 171 MPRTAS 154
P T++
Sbjct: 241 FPTTST 246
>BC117319-1|AAI17320.1| 257|Homo sapiens TPRXL protein protein.
Length = 257
Score = 29.9 bits (64), Expect = 5.5
Identities = 24/97 (24%), Positives = 47/97 (48%)
Frame = -1
Query: 393 ASSPNEPEPSYVWTTFSTRSSPVTRTSKTPFSMT*KLSPSSPCLITYSPGSDLFSNIASR 214
+SSP+ S ++ S+ SSP + +S + S + S SS + S S S+ S
Sbjct: 71 SSSPSSSHSSSSPSSSSSTSSPSSSSSSSSSSPSSSNSSSSSSSSSPSSSSSSSSSSPSS 130
Query: 213 TCCICCASRERNSSMPRTASARRALCASDLGNTAGAP 103
+ +S +SS P ++S+ + +S +++ +P
Sbjct: 131 SSSSPSSSSSSSSSSPSSSSSSPSSSSSSSSSSSSSP 167
>AK223527-1|BAD97247.1| 257|Homo sapiens folate receptor 1
precursor variant protein.
Length = 257
Score = 29.9 bits (64), Expect = 5.5
Identities = 14/34 (41%), Positives = 18/34 (52%), Gaps = 1/34 (2%)
Frame = +3
Query: 408 CRGRHLYGPRPPALCGP-WTATRSVASCSRAHSR 506
C+ HLY P P LC WT + V++ SR R
Sbjct: 175 CQPFHLYFPTPTVLCNEIWTHSYKVSNYSRGSGR 208
>AJ298318-1|CAC83675.1| 1349|Homo sapiens mucin 5 protein.
Length = 1349
Score = 29.5 bits (63), Expect = 7.3
Identities = 22/66 (33%), Positives = 33/66 (50%)
Frame = -1
Query: 351 TFSTRSSPVTRTSKTPFSMT*KLSPSSPCLITYSPGSDLFSNIASRTCCICCASRERNSS 172
T ST S+P T T+ TP + +S + T +P S S I++RT I A +S
Sbjct: 363 TTSTTSAPTTSTTSTPQT---SISSAPTSSTTSAPTS---STISARTTSIISAPTTSTTS 416
Query: 171 MPRTAS 154
P T++
Sbjct: 417 SPTTST 422
>Z83844-7|CAI20371.1| 2193|Homo sapiens protein ( S domain
containing protein ).).
Length = 2193
Score = 29.1 bits (62), Expect = 9.7
Identities = 23/85 (27%), Positives = 36/85 (42%)
Frame = -1
Query: 396 RASSPNEPEPSYVWTTFSTRSSPVTRTSKTPFSMT*KLSPSSPCLITYSPGSDLFSNIAS 217
RASSPN T+ + R +P + +P T + +P + C +P + +
Sbjct: 365 RASSPNRAARDNPTTSCAQRDNPRASRTSSPNRAT-RDNPRTSCAQRDNPRASSPNRATR 423
Query: 216 RTCCICCASRERNSSMPRTASARRA 142
CA R+ N RT+S RA
Sbjct: 424 DNPTTSCAQRD-NPRASRTSSPNRA 447
>DQ278603-1|ABB77204.1| 2266|Homo sapiens trio-associated repeat on
actin protein.
Length = 2266
Score = 29.1 bits (62), Expect = 9.7
Identities = 23/85 (27%), Positives = 36/85 (42%)
Frame = -1
Query: 396 RASSPNEPEPSYVWTTFSTRSSPVTRTSKTPFSMT*KLSPSSPCLITYSPGSDLFSNIAS 217
RASSPN T+ + R +P + +P T + +P + C +P + +
Sbjct: 537 RASSPNRAARDNPTTSCAQRDNPRASRTSSPNRAT-RDNPRTSCAQRDNPRASSPNRATR 595
Query: 216 RTCCICCASRERNSSMPRTASARRA 142
CA R+ N RT+S RA
Sbjct: 596 DNPTTSCAQRD-NPRASRTSSPNRA 619
>DQ228005-1|ABB59561.1| 2365|Homo sapiens TRIOBP isoform 6 protein.
Length = 2365
Score = 29.1 bits (62), Expect = 9.7
Identities = 23/85 (27%), Positives = 36/85 (42%)
Frame = -1
Query: 396 RASSPNEPEPSYVWTTFSTRSSPVTRTSKTPFSMT*KLSPSSPCLITYSPGSDLFSNIAS 217
RASSPN T+ + R +P + +P T + +P + C +P + +
Sbjct: 537 RASSPNRAARDNPTTSCAQRDNPRASRTSSPNRAT-RDNPRTSCAQRDNPRASSPNRATR 595
Query: 216 RTCCICCASRERNSSMPRTASARRA 142
CA R+ N RT+S RA
Sbjct: 596 DNPTTSCAQRD-NPRASRTSSPNRA 619
>DQ228004-1|ABB59560.1| 1144|Homo sapiens TRIOBP isoform 4 protein.
Length = 1144
Score = 29.1 bits (62), Expect = 9.7
Identities = 23/85 (27%), Positives = 36/85 (42%)
Frame = -1
Query: 396 RASSPNEPEPSYVWTTFSTRSSPVTRTSKTPFSMT*KLSPSSPCLITYSPGSDLFSNIAS 217
RASSPN T+ + R +P + +P T + +P + C +P + +
Sbjct: 365 RASSPNRAARDNPTTSCAQRDNPRASRTSSPNRAT-RDNPRTSCAQRDNPRASSPNRATR 423
Query: 216 RTCCICCASRERNSSMPRTASARRA 142
CA R+ N RT+S RA
Sbjct: 424 DNPTTSCAQRD-NPRASRTSSPNRA 447
>DQ228003-1|ABB59559.1| 2193|Homo sapiens TRIOBP isoform 3 protein.
Length = 2193
Score = 29.1 bits (62), Expect = 9.7
Identities = 23/85 (27%), Positives = 36/85 (42%)
Frame = -1
Query: 396 RASSPNEPEPSYVWTTFSTRSSPVTRTSKTPFSMT*KLSPSSPCLITYSPGSDLFSNIAS 217
RASSPN T+ + R +P + +P T + +P + C +P + +
Sbjct: 365 RASSPNRAARDNPTTSCAQRDNPRASRTSSPNRAT-RDNPRTSCAQRDNPRASSPNRATR 423
Query: 216 RTCCICCASRERNSSMPRTASARRA 142
CA R+ N RT+S RA
Sbjct: 424 DNPTTSCAQRD-NPRASRTSSPNRA 447
>BC050522-1|AAH50522.1| 970|Homo sapiens DDX11 protein protein.
Length = 970
Score = 29.1 bits (62), Expect = 9.7
Identities = 15/39 (38%), Positives = 16/39 (41%), Gaps = 2/39 (5%)
Frame = -2
Query: 230 RTSHPEPAAFAARQENGTAVCPG--PPQRDGLSVRPTWG 120
R H P F R G A+CP P Q GL P G
Sbjct: 844 RQGHQAPEGFCQRSAPGPAICPAPCPGQAAGLDPSPCGG 882
>AY053503-1|AAL15429.1| 1107|Homo sapiens ether-a-go-go-like
potassium channel 1 protein.
Length = 1107
Score = 29.1 bits (62), Expect = 9.7
Identities = 12/26 (46%), Positives = 17/26 (65%)
Frame = +2
Query: 245 PGEYVIRQGDDGDNFYVIENGVFDVL 322
PGEY++RQGD Y + +G +VL
Sbjct: 574 PGEYLLRQGDALQAIYFVCSGSMEVL 599
>AB209053-1|BAD92290.1| 583|Homo sapiens potassium voltage-gated
channel, subfamily H, member 8 variant protein.
Length = 583
Score = 29.1 bits (62), Expect = 9.7
Identities = 12/26 (46%), Positives = 17/26 (65%)
Frame = +2
Query: 245 PGEYVIRQGDDGDNFYVIENGVFDVL 322
PGEY++RQGD Y + +G +VL
Sbjct: 50 PGEYLLRQGDALQAIYFVCSGSMEVL 75
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 80,230,409
Number of Sequences: 237096
Number of extensions: 1807111
Number of successful extensions: 7580
Number of sequences better than 10.0: 115
Number of HSP's better than 10.0 without gapping: 6858
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7487
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4876707572
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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