Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= epV30063
(825 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X04412-1|CAA28000.1| 782|Homo sapiens plasma gelsolin protein. 217 4e-56
BC026033-1|AAH26033.1| 782|Homo sapiens gelsolin (amyloidosis, ... 217 4e-56
AL513122-6|CAM20459.1| 731|Homo sapiens gelsolin (amyloidosis, ... 217 4e-56
AL513122-5|CAI14415.1| 260|Homo sapiens gelsolin (amyloidosis, ... 217 4e-56
AL513122-4|CAI14414.1| 228|Homo sapiens gelsolin (amyloidosis, ... 217 4e-56
AL513122-3|CAI14413.1| 782|Homo sapiens gelsolin (amyloidosis, ... 217 4e-56
AF276507-1|AAK60494.1| 715|Homo sapiens scinderin protein. 208 2e-53
AC005281-1|AAD15423.1| 527|Homo sapiens WUGSC:H_DJ0722F20.1 pro... 208 2e-53
AB067492-1|BAB67798.1| 626|Homo sapiens KIAA1905 protein protein. 208 2e-53
BC021090-1|AAH21090.1| 715|Homo sapiens SCIN protein protein. 207 3e-53
AK075123-1|BAC11416.1| 715|Homo sapiens protein ( Homo sapiens ... 206 6e-53
AF041449-1|AAC25051.1| 819|Homo sapiens advillin protein. 190 5e-48
X12901-1|CAA31386.1| 827|Homo sapiens protein ( Human mRNA for ... 182 2e-45
BC017303-1|AAH17303.1| 421|Homo sapiens VIL1 protein protein. 182 2e-45
AK223398-1|BAD97118.1| 827|Homo sapiens villin 1 variant protein. 182 2e-45
BC111730-1|AAI11731.1| 812|Homo sapiens AVIL protein protein. 176 7e-44
M94345-1|AAA59570.1| 348|Homo sapiens macrophage capping protei... 165 1e-40
BC014549-1|AAH14549.1| 348|Homo sapiens capping protein (actin ... 165 1e-40
BC000728-1|AAH00728.1| 348|Homo sapiens capping protein (actin ... 165 1e-40
AC062037-3|AAY24128.1| 348|Homo sapiens unknown protein. 165 1e-40
U12026-1|AAA92670.1| 172|Homo sapiens Cap-G protein. 133 8e-31
U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein. 126 1e-28
U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog prot... 126 1e-28
BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog (D... 126 1e-28
AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog va... 126 1e-28
AL513122-7|CAI14416.1| 485|Homo sapiens gelsolin (amyloidosis, ... 93 8e-19
AK075198-1|BAC11465.1| 396|Homo sapiens protein ( Homo sapiens ... 78 3e-14
AK027778-1|BAB55361.1| 468|Homo sapiens protein ( Homo sapiens ... 78 3e-14
BC075797-1|AAH75797.1| 85|Homo sapiens Unknown (protein for MG... 73 2e-12
X07066-1|CAA30102.1| 69|Homo sapiens protein ( Human gene for ... 71 4e-12
AL160060-2|CAH71300.1| 2214|Homo sapiens supervillin protein. 59 9e-09
AL158167-3|CAI15237.1| 2214|Homo sapiens supervillin protein. 59 9e-09
AF109135-1|AAD14682.1| 2214|Homo sapiens archvillin protein. 59 9e-09
AL160060-1|CAH71301.1| 1788|Homo sapiens supervillin protein. 59 9e-09
AL158167-2|CAI15236.1| 1788|Homo sapiens supervillin protein. 59 9e-09
AF051851-1|AAC64696.1| 1788|Homo sapiens supervillin protein. 59 9e-09
AF051850-1|AAC64695.1| 1788|Homo sapiens supervillin protein. 59 9e-09
D88154-1|BAA21668.1| 686|Homo sapiens villin-like protein protein. 60 1e-08
BC004300-1|AAH04300.1| 672|Homo sapiens VILL protein protein. 60 1e-08
BC000243-1|AAH00243.1| 686|Homo sapiens VILL protein protein. 60 1e-08
BC017491-1|AAH17491.1| 285|Homo sapiens Similar to gelsolin (am... 56 1e-07
AK092426-1|BAC03887.1| 258|Homo sapiens protein ( Homo sapiens ... 38 0.058
BC117319-1|AAI17320.1| 257|Homo sapiens TPRXL protein protein. 35 0.31
AL513122-9|CAI14417.1| 207|Homo sapiens gelsolin (amyloidosis, ... 32 2.2
Z37352-1|CAA85604.1| 124|Homo sapiens immunoglobulin lambda cha... 32 2.9
BC106877-1|AAI06878.1| 663|Homo sapiens chromosome 1 open readi... 32 2.9
AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ ... 32 2.9
AK001763-1|BAA91892.1| 663|Homo sapiens protein ( Homo sapiens ... 32 2.9
AF063745-1|AAC16826.1| 109|Homo sapiens immunoglobulin lambda l... 31 5.1
U77456-1|AAC50870.1| 375|Homo sapiens nucleosome assembly prote... 31 6.7
BC022090-1|AAH22090.1| 375|Homo sapiens nucleosome assembly pro... 31 6.7
D31661-1|BAA06506.1| 981|Homo sapiens tyrosine kinase precursor... 30 8.8
AY307931-1|AAQ73825.1| 336|Homo sapiens intestinal mucin MUC3B ... 30 8.8
>X04412-1|CAA28000.1| 782|Homo sapiens plasma gelsolin protein.
Length = 782
Score = 217 bits (530), Expect = 4e-56
Identities = 103/206 (50%), Positives = 140/206 (67%), Gaps = 1/206 (0%)
Frame = +1
Query: 16 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 192
H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++ L +D+H+W
Sbjct: 56 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 115
Query: 193 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHAS 372
LG+ SQDE+GAAAI TV LDD G AVQHREVQ +ES FL YF ++Y KGG AS
Sbjct: 116 LGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVAS 174
Query: 373 GFSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKG 552
GF HV NE +RLFQ+KG+R VR +V ++ES NNGDCFILD+ + I + G +
Sbjct: 175 GFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNR 234
Query: 553 VERMKAITVANQIKDQDHNGRADIEV 630
ER+KA V+ I+D + +GRA + V
Sbjct: 235 YERLKATQVSKGIRDNERSGRARVHV 260
Score = 93.5 bits (222), Expect = 8e-19
Identities = 73/214 (34%), Positives = 103/214 (48%), Gaps = 4/214 (1%)
Frame = +1
Query: 55 EIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAAA 234
+IWRIE V V +G FY GDSYI+L R I+ W G++++QDE A+A
Sbjct: 448 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASA 507
Query: 235 ILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYLKGGHASGFSHVTINEGTE 408
ILT L DE+ G+ VQ R VQ E + F P I Y KGG S T T
Sbjct: 508 ILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIY-KGG-TSREGGQTAPAST- 563
Query: 409 KRLFQIKGKR--NVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVA 582
RLFQ++ R +V P +LN+ D F+L +++VG A E+ A +
Sbjct: 564 -RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELL 622
Query: 583 NQIKDQDHNGRADIEVVDSEAHDGIFDRFFDALG 684
++ Q ++V + DG F++ALG
Sbjct: 623 RVLRAQ------PVQVAEGSEPDG----FWEALG 646
Score = 47.6 bits (108), Expect = 5e-05
Identities = 45/173 (26%), Positives = 77/173 (44%), Gaps = 8/173 (4%)
Frame = +1
Query: 178 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLK 357
+IH W GS +++ E A ++ + D + G A H + E + L+ P L
Sbjct: 223 NIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPK-PALP 281
Query: 358 GGHASGFSHVTINEGTEKRLFQIK---GKRNVRVKQVKPTFE--SLNNGDCFILD--VDH 516
G N K L+++ G +V + + F +L + DCFILD D
Sbjct: 282 AGTEDTAKEDAANRKLAK-LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDG 340
Query: 517 QIFVFVGEKAKGVERMKAI-TVANQIKDQDHNGRADIEVVDSEAHDGIFDRFF 672
+IFV+ G++A ER A+ T ++ I D+ + + V+ +F +FF
Sbjct: 341 KIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFF 393
Score = 32.3 bits (70), Expect = 2.2
Identities = 16/48 (33%), Positives = 27/48 (56%)
Frame = +1
Query: 472 ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 615
E L D +LD Q+FV+VG+ ++ E+ +A+T A + + D R
Sbjct: 691 EDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANR 738
>BC026033-1|AAH26033.1| 782|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 782
Score = 217 bits (530), Expect = 4e-56
Identities = 103/206 (50%), Positives = 140/206 (67%), Gaps = 1/206 (0%)
Frame = +1
Query: 16 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 192
H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++ L +D+H+W
Sbjct: 56 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 115
Query: 193 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHAS 372
LG+ SQDE+GAAAI TV LDD G AVQHREVQ +ES FL YF ++Y KGG AS
Sbjct: 116 LGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVAS 174
Query: 373 GFSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKG 552
GF HV NE +RLFQ+KG+R VR +V ++ES NNGDCFILD+ + I + G +
Sbjct: 175 GFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNR 234
Query: 553 VERMKAITVANQIKDQDHNGRADIEV 630
ER+KA V+ I+D + +GRA + V
Sbjct: 235 YERLKATQVSKGIRDNERSGRARVHV 260
Score = 93.5 bits (222), Expect = 8e-19
Identities = 73/214 (34%), Positives = 103/214 (48%), Gaps = 4/214 (1%)
Frame = +1
Query: 55 EIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAAA 234
+IWRIE V V +G FY GDSYI+L R I+ W G++++QDE A+A
Sbjct: 448 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASA 507
Query: 235 ILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYLKGGHASGFSHVTINEGTE 408
ILT L DE+ G+ VQ R VQ E + F P I Y KGG S T T
Sbjct: 508 ILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIY-KGG-TSREGGQTAPAST- 563
Query: 409 KRLFQIKGKR--NVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVA 582
RLFQ++ R +V P +LN+ D F+L +++VG A E+ A +
Sbjct: 564 -RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELL 622
Query: 583 NQIKDQDHNGRADIEVVDSEAHDGIFDRFFDALG 684
++ Q ++V + DG F++ALG
Sbjct: 623 RVLRAQ------PVQVAEGSEPDG----FWEALG 646
Score = 47.6 bits (108), Expect = 5e-05
Identities = 45/173 (26%), Positives = 77/173 (44%), Gaps = 8/173 (4%)
Frame = +1
Query: 178 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLK 357
+IH W GS +++ E A ++ + D + G A H + E + L+ P L
Sbjct: 223 NIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPK-PALP 281
Query: 358 GGHASGFSHVTINEGTEKRLFQIK---GKRNVRVKQVKPTFE--SLNNGDCFILD--VDH 516
G N K L+++ G +V + + F +L + DCFILD D
Sbjct: 282 AGTEDTAKEDAANRKLAK-LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDG 340
Query: 517 QIFVFVGEKAKGVERMKAI-TVANQIKDQDHNGRADIEVVDSEAHDGIFDRFF 672
+IFV+ G++A ER A+ T ++ I D+ + + V+ +F +FF
Sbjct: 341 KIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFF 393
Score = 32.3 bits (70), Expect = 2.2
Identities = 16/48 (33%), Positives = 27/48 (56%)
Frame = +1
Query: 472 ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 615
E L D +LD Q+FV+VG+ ++ E+ +A+T A + + D R
Sbjct: 691 EDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANR 738
>AL513122-6|CAM20459.1| 731|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 731
Score = 217 bits (530), Expect = 4e-56
Identities = 103/206 (50%), Positives = 140/206 (67%), Gaps = 1/206 (0%)
Frame = +1
Query: 16 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 192
H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++ L +D+H+W
Sbjct: 5 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 64
Query: 193 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHAS 372
LG+ SQDE+GAAAI TV LDD G AVQHREVQ +ES FL YF ++Y KGG AS
Sbjct: 65 LGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVAS 123
Query: 373 GFSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKG 552
GF HV NE +RLFQ+KG+R VR +V ++ES NNGDCFILD+ + I + G +
Sbjct: 124 GFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNR 183
Query: 553 VERMKAITVANQIKDQDHNGRADIEV 630
ER+KA V+ I+D + +GRA + V
Sbjct: 184 YERLKATQVSKGIRDNERSGRARVHV 209
Score = 93.5 bits (222), Expect = 8e-19
Identities = 73/214 (34%), Positives = 103/214 (48%), Gaps = 4/214 (1%)
Frame = +1
Query: 55 EIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAAA 234
+IWRIE V V +G FY GDSYI+L R I+ W G++++QDE A+A
Sbjct: 397 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASA 456
Query: 235 ILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYLKGGHASGFSHVTINEGTE 408
ILT L DE+ G+ VQ R VQ E + F P I Y KGG S T T
Sbjct: 457 ILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIY-KGG-TSREGGQTAPAST- 512
Query: 409 KRLFQIKGKR--NVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVA 582
RLFQ++ R +V P +LN+ D F+L +++VG A E+ A +
Sbjct: 513 -RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELL 571
Query: 583 NQIKDQDHNGRADIEVVDSEAHDGIFDRFFDALG 684
++ Q ++V + DG F++ALG
Sbjct: 572 RVLRAQ------PVQVAEGSEPDG----FWEALG 595
Score = 47.6 bits (108), Expect = 5e-05
Identities = 45/173 (26%), Positives = 77/173 (44%), Gaps = 8/173 (4%)
Frame = +1
Query: 178 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLK 357
+IH W GS +++ E A ++ + D + G A H + E + L+ P L
Sbjct: 172 NIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPK-PALP 230
Query: 358 GGHASGFSHVTINEGTEKRLFQIK---GKRNVRVKQVKPTFE--SLNNGDCFILD--VDH 516
G N K L+++ G +V + + F +L + DCFILD D
Sbjct: 231 AGTEDTAKEDAANRKLAK-LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDG 289
Query: 517 QIFVFVGEKAKGVERMKAI-TVANQIKDQDHNGRADIEVVDSEAHDGIFDRFF 672
+IFV+ G++A ER A+ T ++ I D+ + + V+ +F +FF
Sbjct: 290 KIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFF 342
Score = 32.3 bits (70), Expect = 2.2
Identities = 16/48 (33%), Positives = 27/48 (56%)
Frame = +1
Query: 472 ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 615
E L D +LD Q+FV+VG+ ++ E+ +A+T A + + D R
Sbjct: 640 EDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANR 687
>AL513122-5|CAI14415.1| 260|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 260
Score = 217 bits (530), Expect = 4e-56
Identities = 103/206 (50%), Positives = 140/206 (67%), Gaps = 1/206 (0%)
Frame = +1
Query: 16 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 192
H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++ L +D+H+W
Sbjct: 5 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 64
Query: 193 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHAS 372
LG+ SQDE+GAAAI TV LDD G AVQHREVQ +ES FL YF ++Y KGG AS
Sbjct: 65 LGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVAS 123
Query: 373 GFSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKG 552
GF HV NE +RLFQ+KG+R VR +V ++ES NNGDCFILD+ + I + G +
Sbjct: 124 GFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNR 183
Query: 553 VERMKAITVANQIKDQDHNGRADIEV 630
ER+KA V+ I+D + +GRA + V
Sbjct: 184 YERLKATQVSKGIRDNERSGRARVHV 209
>AL513122-4|CAI14414.1| 228|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 228
Score = 217 bits (530), Expect = 4e-56
Identities = 103/206 (50%), Positives = 140/206 (67%), Gaps = 1/206 (0%)
Frame = +1
Query: 16 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 192
H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++ L +D+H+W
Sbjct: 16 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 75
Query: 193 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHAS 372
LG+ SQDE+GAAAI TV LDD G AVQHREVQ +ES FL YF ++Y KGG AS
Sbjct: 76 LGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVAS 134
Query: 373 GFSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKG 552
GF HV NE +RLFQ+KG+R VR +V ++ES NNGDCFILD+ + I + G +
Sbjct: 135 GFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNR 194
Query: 553 VERMKAITVANQIKDQDHNGRADIEV 630
ER+KA V+ I+D + +GRA + V
Sbjct: 195 YERLKATQVSKGIRDNERSGRARVHV 220
>AL513122-3|CAI14413.1| 782|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 782
Score = 217 bits (530), Expect = 4e-56
Identities = 103/206 (50%), Positives = 140/206 (67%), Gaps = 1/206 (0%)
Frame = +1
Query: 16 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 192
H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++ L +D+H+W
Sbjct: 56 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 115
Query: 193 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHAS 372
LG+ SQDE+GAAAI TV LDD G AVQHREVQ +ES FL YF ++Y KGG AS
Sbjct: 116 LGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVAS 174
Query: 373 GFSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKG 552
GF HV NE +RLFQ+KG+R VR +V ++ES NNGDCFILD+ + I + G +
Sbjct: 175 GFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNR 234
Query: 553 VERMKAITVANQIKDQDHNGRADIEV 630
ER+KA V+ I+D + +GRA + V
Sbjct: 235 YERLKATQVSKGIRDNERSGRARVHV 260
Score = 93.5 bits (222), Expect = 8e-19
Identities = 73/214 (34%), Positives = 103/214 (48%), Gaps = 4/214 (1%)
Frame = +1
Query: 55 EIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAAA 234
+IWRIE V V +G FY GDSYI+L R I+ W G++++QDE A+A
Sbjct: 448 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASA 507
Query: 235 ILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYLKGGHASGFSHVTINEGTE 408
ILT L DE+ G+ VQ R VQ E + F P I Y KGG S T T
Sbjct: 508 ILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIY-KGG-TSREGGQTAPAST- 563
Query: 409 KRLFQIKGKR--NVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVA 582
RLFQ++ R +V P +LN+ D F+L +++VG A E+ A +
Sbjct: 564 -RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELL 622
Query: 583 NQIKDQDHNGRADIEVVDSEAHDGIFDRFFDALG 684
++ Q ++V + DG F++ALG
Sbjct: 623 RVLRAQ------PVQVAEGSEPDG----FWEALG 646
Score = 47.6 bits (108), Expect = 5e-05
Identities = 45/173 (26%), Positives = 77/173 (44%), Gaps = 8/173 (4%)
Frame = +1
Query: 178 DIHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLK 357
+IH W GS +++ E A ++ + D + G A H + E + L+ P L
Sbjct: 223 NIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPK-PALP 281
Query: 358 GGHASGFSHVTINEGTEKRLFQIK---GKRNVRVKQVKPTFE--SLNNGDCFILD--VDH 516
G N K L+++ G +V + + F +L + DCFILD D
Sbjct: 282 AGTEDTAKEDAANRKLAK-LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDG 340
Query: 517 QIFVFVGEKAKGVERMKAI-TVANQIKDQDHNGRADIEVVDSEAHDGIFDRFF 672
+IFV+ G++A ER A+ T ++ I D+ + + V+ +F +FF
Sbjct: 341 KIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFF 393
Score = 32.3 bits (70), Expect = 2.2
Identities = 16/48 (33%), Positives = 27/48 (56%)
Frame = +1
Query: 472 ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 615
E L D +LD Q+FV+VG+ ++ E+ +A+T A + + D R
Sbjct: 691 EDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANR 738
>AF276507-1|AAK60494.1| 715|Homo sapiens scinderin protein.
Length = 715
Score = 208 bits (507), Expect = 2e-53
Identities = 109/267 (40%), Positives = 159/267 (59%), Gaps = 2/267 (0%)
Frame = +1
Query: 16 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 195
H+ FA AG++ GL++WRIE E V VP++ G FY GD+Y+VL+T T+ +HFWL
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWL 66
Query: 196 GSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASG 375
G SQDE+ AAAI TV +DD G VQ+RE+Q YES +F+ YF ++Y GG ASG
Sbjct: 67 GKECSQDESTAAAIFTVQMDD-YLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125
Query: 376 FSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGV 555
+HV N+ T KRL +KG+R VR +V +++S N GDCFI+D+ +I+ + G
Sbjct: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185
Query: 556 ERMKAITVANQIKDQDHNGRADIEVVDSEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQ 735
ER+KA VA I+ + GR+++ VV+ + + G K + D GGDD
Sbjct: 186 ERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVL-----GEKPELPD---GGDDD 237
Query: 736 EFECVVT--KEVSLSEISDKTGSIRIT 810
+ ++ K L +SD +GS+R+T
Sbjct: 238 DIIADISNRKMAKLYMVSDASGSMRVT 264
Score = 78.6 bits (185), Expect = 3e-14
Identities = 67/205 (32%), Positives = 96/205 (46%), Gaps = 7/205 (3%)
Frame = +1
Query: 1 KMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWD 180
+M H D K +EIWR+EN + V + +G FY GD YI+L T + ++
Sbjct: 383 QMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI--- 436
Query: 181 IHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYL 354
I+ W G+ ++DE +A LTV L D G AVQ R Q E L F P I Y
Sbjct: 437 IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQDKEPVHLLSLFKDKPLIIYK 495
Query: 355 KGGHASGFSHVTINEGTEKRLFQIKGKRNV----RVKQVKPTFESLNNGDCFILDVDHQI 522
G G RLFQ+ +RN+ R+ +V SLN+ D F+L +
Sbjct: 496 NGTSKKGGQ----APAPPTRLFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLSQNS 549
Query: 523 -FVFVGEKAKGVERMKAITVANQIK 594
+++VG+ A E A VA+ +K
Sbjct: 550 GYIWVGKGASQEEEKGAEYVASVLK 574
Score = 35.1 bits (77), Expect = 0.31
Identities = 16/50 (32%), Positives = 28/50 (56%)
Frame = +1
Query: 466 TFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 615
T + L D +LD QIF+++G+ A VE+ +++ A + D +GR
Sbjct: 636 TQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGR 685
>AC005281-1|AAD15423.1| 527|Homo sapiens WUGSC:H_DJ0722F20.1
protein.
Length = 527
Score = 208 bits (507), Expect = 2e-53
Identities = 109/267 (40%), Positives = 159/267 (59%), Gaps = 2/267 (0%)
Frame = +1
Query: 16 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 195
H+ FA AG++ GL++WRIE E V VP++ G FY GD+Y+VL+T T+ +HFWL
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWL 66
Query: 196 GSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASG 375
G SQDE+ AAAI TV +DD G VQ+RE+Q YES +F+ YF ++Y GG ASG
Sbjct: 67 GKECSQDESTAAAIFTVQMDD-YLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125
Query: 376 FSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGV 555
+HV N+ T KRL +KG+R VR +V +++S N GDCFI+D+ +I+ + G
Sbjct: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185
Query: 556 ERMKAITVANQIKDQDHNGRADIEVVDSEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQ 735
ER+KA VA I+ + GR+++ VV+ + + G K + D GGDD
Sbjct: 186 ERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVL-----GEKPELPD---GGDDD 237
Query: 736 EFECVVT--KEVSLSEISDKTGSIRIT 810
+ ++ K L +SD +GS+R+T
Sbjct: 238 DIIADISNRKMAKLYMVSDASGSMRVT 264
Score = 63.3 bits (147), Expect = 1e-09
Identities = 45/127 (35%), Positives = 60/127 (47%), Gaps = 2/127 (1%)
Frame = +1
Query: 1 KMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWD 180
+M H D K +EIWR+EN + V + +G FY GD YI+L T + ++
Sbjct: 383 QMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI--- 436
Query: 181 IHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYL 354
I+ W G+ ++DE +A LTV L D G AVQ R Q E L F P I Y
Sbjct: 437 IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYK 495
Query: 355 KGGHASG 375
G G
Sbjct: 496 NGTSKKG 502
>AB067492-1|BAB67798.1| 626|Homo sapiens KIAA1905 protein protein.
Length = 626
Score = 208 bits (507), Expect = 2e-53
Identities = 109/267 (40%), Positives = 159/267 (59%), Gaps = 2/267 (0%)
Frame = +1
Query: 16 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 195
H+ FA AG++ GL++WRIE E V VP++ G FY GD+Y+VL+T T+ +HFWL
Sbjct: 53 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWL 112
Query: 196 GSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASG 375
G SQDE+ AAAI TV +DD G VQ+RE+Q YES +F+ YF ++Y GG ASG
Sbjct: 113 GKECSQDESTAAAIFTVQMDD-YLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 171
Query: 376 FSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGV 555
+HV N+ T KRL +KG+R VR +V +++S N GDCFI+D+ +I+ + G
Sbjct: 172 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 231
Query: 556 ERMKAITVANQIKDQDHNGRADIEVVDSEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQ 735
ER+KA VA I+ + GR+++ VV+ + + G K + D GGDD
Sbjct: 232 ERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVL-----GEKPELPD---GGDDD 283
Query: 736 EFECVVT--KEVSLSEISDKTGSIRIT 810
+ ++ K L +SD +GS+R+T
Sbjct: 284 DIIADISNRKMAKLYMVSDASGSMRVT 310
Score = 63.3 bits (147), Expect = 1e-09
Identities = 45/127 (35%), Positives = 60/127 (47%), Gaps = 2/127 (1%)
Frame = +1
Query: 1 KMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWD 180
+M H D K +EIWR+EN + V + +G FY GD YI+L T + ++
Sbjct: 429 QMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI--- 482
Query: 181 IHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYL 354
I+ W G+ ++DE +A LTV L D G AVQ R Q E L F P I Y
Sbjct: 483 IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYK 541
Query: 355 KGGHASG 375
G G
Sbjct: 542 NGTSKKG 548
>BC021090-1|AAH21090.1| 715|Homo sapiens SCIN protein protein.
Length = 715
Score = 207 bits (506), Expect = 3e-53
Identities = 109/267 (40%), Positives = 159/267 (59%), Gaps = 2/267 (0%)
Frame = +1
Query: 16 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 195
H+ FA AG++ GL++WRIE E V VP++ G FY GD+Y+VL+T T+ +HFWL
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYRLHFWL 66
Query: 196 GSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASG 375
G SQDE+ AAAI TV +DD G VQ+RE+Q YES +F+ YF ++Y GG ASG
Sbjct: 67 GKECSQDESTAAAIFTVQMDD-YLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125
Query: 376 FSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGV 555
+HV N+ T KRL +KG+R VR +V +++S N GDCFI+D+ +I+ + G
Sbjct: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185
Query: 556 ERMKAITVANQIKDQDHNGRADIEVVDSEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQ 735
ER+KA VA I+ + GR+++ VV+ + + G K + D GGDD
Sbjct: 186 ERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVL-----GEKPELPD---GGDDD 237
Query: 736 EFECVVT--KEVSLSEISDKTGSIRIT 810
+ ++ K L +SD +GS+R+T
Sbjct: 238 DIIADISNRKMAKLYMVSDASGSMRVT 264
Score = 78.2 bits (184), Expect = 3e-14
Identities = 67/205 (32%), Positives = 97/205 (47%), Gaps = 7/205 (3%)
Frame = +1
Query: 1 KMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWD 180
+M H D K +EIWR+EN + V + +G FY GD YI+L T + ++
Sbjct: 383 QMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI--- 436
Query: 181 IHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYL 354
I+ W G+ ++DE +A LTV L D G AVQ R Q E L F P I Y
Sbjct: 437 IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYK 495
Query: 355 KGGHASGFSHVTINEGTEKRLFQIKGKRNV----RVKQVKPTFESLNNGDCFILDV-DHQ 519
G G RLFQ+ +RN+ R+ +V SLN+ D F+L + +
Sbjct: 496 NGTSKKGGQ----APAPPTRLFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLPQNS 549
Query: 520 IFVFVGEKAKGVERMKAITVANQIK 594
+++VG+ A E A VA+ +K
Sbjct: 550 GYIWVGKGASQEEEKGAEYVASVLK 574
Score = 35.1 bits (77), Expect = 0.31
Identities = 16/50 (32%), Positives = 28/50 (56%)
Frame = +1
Query: 466 TFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 615
T + L D +LD QIF+++G+ A VE+ +++ A + D +GR
Sbjct: 636 TQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGR 685
>AK075123-1|BAC11416.1| 715|Homo sapiens protein ( Homo sapiens
cDNA FLJ90642 fis, clone PLACE1004078, highly similar to
Bovine mRNA for adseverin. ).
Length = 715
Score = 206 bits (504), Expect = 6e-53
Identities = 108/267 (40%), Positives = 159/267 (59%), Gaps = 2/267 (0%)
Frame = +1
Query: 16 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 195
H+ FA AG++ GL++WRIE E V VP++ G FY GD+Y++L+T T+ +HFWL
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLMLHTAKTSRGFTYHLHFWL 66
Query: 196 GSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASG 375
G SQDE+ AAAI TV +DD G VQ+RE+Q YES +F+ YF ++Y GG ASG
Sbjct: 67 GKECSQDESTAAAIFTVQMDD-YLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125
Query: 376 FSHVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGV 555
+HV N+ T KRL +KG+R VR +V +++S N GDCFI+D+ +I+ + G
Sbjct: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185
Query: 556 ERMKAITVANQIKDQDHNGRADIEVVDSEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQ 735
ER+KA VA I+ + GR+++ VV+ + + G K + D GGDD
Sbjct: 186 ERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVL-----GEKPELPD---GGDDD 237
Query: 736 EFECVVT--KEVSLSEISDKTGSIRIT 810
+ ++ K L +SD +GS+R+T
Sbjct: 238 DIIADISNRKMAKLYMVSDASGSMRVT 264
Score = 78.2 bits (184), Expect = 3e-14
Identities = 67/205 (32%), Positives = 97/205 (47%), Gaps = 7/205 (3%)
Frame = +1
Query: 1 KMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWD 180
+M H D K +EIWR+EN + V + +G FY GD YI+L T + ++
Sbjct: 383 QMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI--- 436
Query: 181 IHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYL 354
I+ W G+ ++DE +A LTV L D G AVQ R Q E L F P I Y
Sbjct: 437 IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYK 495
Query: 355 KGGHASGFSHVTINEGTEKRLFQIKGKRNV----RVKQVKPTFESLNNGDCFILDV-DHQ 519
G G RLFQ+ +RN+ R+ +V SLN+ D F+L + +
Sbjct: 496 NGTSKKGGQ----APAPPTRLFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLPQNS 549
Query: 520 IFVFVGEKAKGVERMKAITVANQIK 594
+++VG+ A E A VA+ +K
Sbjct: 550 GYIWVGKGASQEEEKGAEYVASVLK 574
Score = 35.1 bits (77), Expect = 0.31
Identities = 16/50 (32%), Positives = 28/50 (56%)
Frame = +1
Query: 466 TFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 615
T + L D +LD QIF+++G+ A VE+ +++ A + D +GR
Sbjct: 636 TQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGR 685
>AF041449-1|AAC25051.1| 819|Homo sapiens advillin protein.
Length = 819
Score = 190 bits (463), Expect = 5e-48
Identities = 105/268 (39%), Positives = 147/268 (54%), Gaps = 3/268 (1%)
Frame = +1
Query: 22 AFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGS 201
AF PG+ +WRIE E VP + G FY GD Y++L+T L+ DIHFW+G
Sbjct: 6 AFRAVDNDPGIIVWRIEKMELALVPVSAHGNFYEGDCYVILSTRRVASLLSQDIHFWIGK 65
Query: 202 RTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFS 381
+SQDE AAI T LDD GS VQHREVQY+ES F YF I Y +GG ASG
Sbjct: 66 DSSQDEQSCAAIYTTQLDD-YLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMK 124
Query: 382 HVTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVER 561
HV N KRL +KGKRN+R +V+ +++S N GD F+LD+ I + G ++ ER
Sbjct: 125 HVETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGER 184
Query: 562 MKAITVANQIKDQDHNGRADIEVVDSE---AHDGIFDRFFDALGSGNKEAIADAEEGGDD 732
+KA+ +A I+D++ GRA+I V++ + A + D LG + +E D
Sbjct: 185 LKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVPDEIIDQ 244
Query: 733 QEFECVVTKEVSLSEISDKTGSIRITRL 816
++ + L ISD G + +T +
Sbjct: 245 KQ-----KSTIMLYHISDSAGQLAVTEV 267
Score = 94.7 bits (225), Expect = 4e-19
Identities = 63/192 (32%), Positives = 92/192 (47%), Gaps = 2/192 (1%)
Frame = +1
Query: 52 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAA 231
+E+WRIEN E V V +G FY GD Y+VL T + ++ W SQDE A+
Sbjct: 397 VEVWRIENLELVPVEYQWYGFFYGGDCYLVLYTYEVNGKPHHILYIWQDRHASQDELAAS 456
Query: 232 AILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFSHVTINEGTEK 411
A V + D QF G+AVQ R E + F+ F + +GG +
Sbjct: 457 AYQAVEV-DRQFDGAAVQVRVRMGTEPRHFMAIFKGKLVIFEGGTS---RKGNAEPDPPV 512
Query: 412 RLFQIKG--KRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVAN 585
RLFQI G K N + +V SLN+ D F+L + +++ G+ + G ER A +A+
Sbjct: 513 RLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAEHYLWYGKGSSGDERAMAKELAS 572
Query: 586 QIKDQDHNGRAD 621
+ D N A+
Sbjct: 573 LLCDGSENTVAE 584
Score = 35.9 bits (79), Expect = 0.18
Identities = 21/67 (31%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
Frame = +1
Query: 478 LNNGDCFILDVD-HQIFVFVGEKAKGVERMKAITVA-NQIKDQDHNGRADIEVVDSEAHD 651
LN+ DC+ILD +I+V+ G+ A E+ A++ A IK + + ++E V+ A
Sbjct: 277 LNHDDCYILDQSGTKIYVWKGKGATKAEKQAAMSKALGFIKMKSYPSSTNVETVNDGAES 336
Query: 652 GIFDRFF 672
+F + F
Sbjct: 337 AMFKQLF 343
Score = 35.5 bits (78), Expect = 0.24
Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Frame = +1
Query: 406 EKRLFQIKGKRN--VRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITV 579
+ RLF+ K V + T + LN D +LD Q+F+++G +A E+ A+
Sbjct: 615 QSRLFECSNKTGQFVVTEITDFTQDDLNPTDVMLLDTWDQVFLWIGAEANATEKESALAT 674
Query: 580 ANQIKDQDHNGR 615
A Q +GR
Sbjct: 675 AQQYLHTHPSGR 686
>X12901-1|CAA31386.1| 827|Homo sapiens protein ( Human mRNA for
villin. ).
Length = 827
Score = 182 bits (442), Expect = 2e-45
Identities = 90/199 (45%), Positives = 125/199 (62%)
Frame = +1
Query: 46 PGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAG 225
PGL+IWRIE + V VP + FG F+ GD YI+L L++DIH+W+G +S DE G
Sbjct: 17 PGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASSLSYDIHYWIGQDSSLDEQG 76
Query: 226 AAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFSHVTINEGT 405
AAAI T +DD +G AVQHREVQ ES+ F YF + KGG ASG HV N
Sbjct: 77 AAAIYTTQMDDF-LKGRAVQHREVQGNESEAFRGYFKQGLVIRKGGVASGMKHVETNSYD 135
Query: 406 EKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVAN 585
+RL +KGKRNV +V+ +++S N GD F+LD+ I + G ++ +ER++ +T+A
Sbjct: 136 VQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAK 195
Query: 586 QIKDQDHNGRADIEVVDSE 642
+I+DQ+ GR + VVD E
Sbjct: 196 EIRDQERGGRTYVGVVDGE 214
Score = 89.4 bits (212), Expect = 1e-17
Identities = 78/258 (30%), Positives = 118/258 (45%), Gaps = 2/258 (0%)
Frame = +1
Query: 52 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAA 231
+++WRIEN E V V G FY GD Y++L T ++ + ++ W GS+ SQDE A+
Sbjct: 400 VQVWRIENLELVPVDSKWLGHFYGGDCYLLLYTYLIGEKQHYLLYVWQGSQASQDEITAS 459
Query: 232 AILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFSHVTINEGTEK 411
A V L D+++ G VQ R E + F + +GG + + + G
Sbjct: 460 AYQAVIL-DQKYNGEPVQIRVPMGKEPPHLMSIFKGRMVVYQGGTSRTNN---LETGPST 515
Query: 412 RLFQIK--GKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVAN 585
RLFQ++ G N + +V LN+ D F+L +++ G+ G ER A VA+
Sbjct: 516 RLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKTQSCCYLWCGKGCSGDEREMAKMVAD 575
Query: 586 QIKDQDHNGRADIEVVDSEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFECVVTKEV 765
I R + +VV F+ AL G K A+ + QE V+T
Sbjct: 576 TI------SRTEKQVVVEGQEPA---NFWMAL--GGKAPYANTKR---LQEENLVITPR- 620
Query: 766 SLSEISDKTGSIRITRLP 819
L E S+KTG T +P
Sbjct: 621 -LFECSNKTGRFLATEIP 637
Score = 36.3 bits (80), Expect = 0.13
Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Frame = +1
Query: 412 RLFQIKGKRNVRVKQVKPTF--ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVAN 585
RLF+ K + P F + L D F+LDV Q+F ++G+ A E+ A T A
Sbjct: 620 RLFECSNKTGRFLATEIPDFNQDDLEEDDVFLLDVWDQVFFWIGKHANEEEKKAAATTAQ 679
Query: 586 QIKDQDHNGR 615
+ +GR
Sbjct: 680 EYLKTHPSGR 689
>BC017303-1|AAH17303.1| 421|Homo sapiens VIL1 protein protein.
Length = 421
Score = 182 bits (442), Expect = 2e-45
Identities = 90/199 (45%), Positives = 125/199 (62%)
Frame = +1
Query: 46 PGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAG 225
PGL+IWRIE + V VP + FG F+ GD YI+L L++DIH+W+G +S DE G
Sbjct: 17 PGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASSLSYDIHYWIGQDSSLDEQG 76
Query: 226 AAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFSHVTINEGT 405
AAAI T +DD +G AVQHREVQ ES+ F YF + KGG ASG HV N
Sbjct: 77 AAAIYTTQMDDF-LKGRAVQHREVQGNESEAFRGYFKQGLVIRKGGVASGMKHVETNSYD 135
Query: 406 EKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVAN 585
+RL +KGKRNV +V+ +++S N GD F+LD+ I + G ++ +ER++ +T+A
Sbjct: 136 VQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAK 195
Query: 586 QIKDQDHNGRADIEVVDSE 642
+I+DQ+ GR + VVD E
Sbjct: 196 EIRDQERGGRTYVGVVDGE 214
>AK223398-1|BAD97118.1| 827|Homo sapiens villin 1 variant protein.
Length = 827
Score = 182 bits (442), Expect = 2e-45
Identities = 90/199 (45%), Positives = 125/199 (62%)
Frame = +1
Query: 46 PGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAG 225
PGL+IWRIE + V VP + FG F+ GD YI+L L++DIH+W+G +S DE G
Sbjct: 17 PGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASSLSYDIHYWIGQDSSLDEQG 76
Query: 226 AAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFSHVTINEGT 405
AAAI T +DD +G AVQHREVQ ES+ F YF + KGG ASG HV N
Sbjct: 77 AAAIYTTQMDDF-LKGRAVQHREVQGNESEAFRGYFKQGLVIRKGGVASGMKHVETNSYD 135
Query: 406 EKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVAN 585
+RL +KGKRNV +V+ +++S N GD F+LD+ I + G ++ +ER++ +T+A
Sbjct: 136 VQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAK 195
Query: 586 QIKDQDHNGRADIEVVDSE 642
+I+DQ+ GR + VVD E
Sbjct: 196 EIRDQERGGRTYVGVVDGE 214
Score = 89.4 bits (212), Expect = 1e-17
Identities = 78/258 (30%), Positives = 118/258 (45%), Gaps = 2/258 (0%)
Frame = +1
Query: 52 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAA 231
+++WRIEN E V V G FY GD Y++L T ++ + ++ W GS+ SQDE A+
Sbjct: 400 VQVWRIENLELVPVDSKWLGHFYGGDCYLLLYTYLIGEKQHYLLYVWQGSQASQDEITAS 459
Query: 232 AILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFSHVTINEGTEK 411
A V L D+++ G VQ R E + F + +GG + + + G
Sbjct: 460 AYQAVIL-DQKYNGEPVQIRVPMGKEPPHLMSIFKGRMVVYQGGTSRTNN---LETGPST 515
Query: 412 RLFQIK--GKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVAN 585
RLFQ++ G N + +V LN+ D F+L +++ G+ G ER A VA+
Sbjct: 516 RLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKTQSCCYLWCGKGCSGDEREMAKMVAD 575
Query: 586 QIKDQDHNGRADIEVVDSEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFECVVTKEV 765
I R + +VV F+ AL G K A+ + QE V+T
Sbjct: 576 TI------SRTEKQVVVEGQEPA---NFWMAL--GGKAPYANTKR---LQEENLVITPR- 620
Query: 766 SLSEISDKTGSIRITRLP 819
L E S+KTG T +P
Sbjct: 621 -LFECSNKTGRFLATEIP 637
Score = 36.3 bits (80), Expect = 0.13
Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Frame = +1
Query: 412 RLFQIKGKRNVRVKQVKPTF--ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVAN 585
RLF+ K + P F + L D F+LDV Q+F ++G+ A E+ A T A
Sbjct: 620 RLFECSNKTGRFLATEIPDFNQDDLEEDDVFLLDVWDQVFFWIGKHANEEEKKAAATTAQ 679
Query: 586 QIKDQDHNGR 615
+ +GR
Sbjct: 680 EYLKTHPSGR 689
>BC111730-1|AAI11731.1| 812|Homo sapiens AVIL protein protein.
Length = 812
Score = 176 bits (429), Expect = 7e-44
Identities = 101/266 (37%), Positives = 143/266 (53%), Gaps = 3/266 (1%)
Frame = +1
Query: 28 ADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRT 207
+ G +IW E E VP + G FY GD Y++L+T L+ DIHFW+G +
Sbjct: 2 SSTGHPGSYKIWG-EKMELALVPVSAHGNFYEGDCYVILSTRRVASLLSQDIHFWIGKDS 60
Query: 208 SQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFSHV 387
SQDE AAI T LDD GS VQHREVQY+ES F YF I Y +GG ASG HV
Sbjct: 61 SQDEQSCAAIYTTQLDD-YLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMKHV 119
Query: 388 TINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMK 567
N KRL +KGKRN+R +V+ +++S N GD F+LD+ I + G ++ ER+K
Sbjct: 120 ETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERLK 179
Query: 568 AITVANQIKDQDHNGRADIEVVDSE---AHDGIFDRFFDALGSGNKEAIADAEEGGDDQE 738
A+ +A I+D++ GRA+I V++ + A + D LG + +E D ++
Sbjct: 180 AMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVPDEIIDQKQ 239
Query: 739 FECVVTKEVSLSEISDKTGSIRITRL 816
+ L ISD G + +T +
Sbjct: 240 -----KSTIMLYHISDSAGQLAVTEV 260
Score = 97.5 bits (232), Expect = 5e-20
Identities = 64/192 (33%), Positives = 93/192 (48%), Gaps = 2/192 (1%)
Frame = +1
Query: 52 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAA 231
+E+WRIEN E V V +G FY GD Y+VL T + ++ W G SQDE A+
Sbjct: 390 VEVWRIENLELVPVEYQWYGFFYGGDCYLVLYTYEVNGKPHHILYIWQGRHASQDELAAS 449
Query: 232 AILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGGHASGFSHVTINEGTEK 411
A V + D QF G+AVQ R E + F+ F + +GG +
Sbjct: 450 AYQAVEV-DRQFDGAAVQVRVRMGTEPRHFMAIFKGKLVIFEGGTS---RKGNAEPDPPV 505
Query: 412 RLFQIKG--KRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVAN 585
RLFQI G K N + +V SLN+ D F+L + +++ G+ + G ER A +A+
Sbjct: 506 RLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAEHYLWYGKGSSGDERAMAKELAS 565
Query: 586 QIKDQDHNGRAD 621
+ D N A+
Sbjct: 566 LLCDGSENTVAE 577
Score = 35.9 bits (79), Expect = 0.18
Identities = 21/67 (31%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
Frame = +1
Query: 478 LNNGDCFILDVD-HQIFVFVGEKAKGVERMKAITVA-NQIKDQDHNGRADIEVVDSEAHD 651
LN+ DC+ILD +I+V+ G+ A E+ A++ A IK + + ++E V+ A
Sbjct: 270 LNHDDCYILDQSGTKIYVWKGKGATKAEKQAAMSKALGFIKMKSYPSSTNVETVNDGAES 329
Query: 652 GIFDRFF 672
+F + F
Sbjct: 330 AMFKQLF 336
Score = 35.5 bits (78), Expect = 0.24
Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Frame = +1
Query: 406 EKRLFQIKGKRN--VRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITV 579
+ RLF+ K V + T + LN D +LD Q+F+++G +A E+ A+
Sbjct: 608 QSRLFECSNKTGQFVVTEITDFTQDDLNPTDVMLLDTWDQVFLWIGAEANATEKESALAT 667
Query: 580 ANQIKDQDHNGR 615
A Q +GR
Sbjct: 668 AQQYLHTHPSGR 679
>M94345-1|AAA59570.1| 348|Homo sapiens macrophage capping protein
protein.
Length = 348
Score = 165 bits (402), Expect = 1e-40
Identities = 92/272 (33%), Positives = 150/272 (55%), Gaps = 1/272 (0%)
Frame = +1
Query: 4 MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 183
+P+ F + + PGL +WR+E +PV V + G+F+SGDSY+VL+ ++ +
Sbjct: 5 IPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEE---VSHL 61
Query: 184 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 363
H W+G ++S+DE GA A+L V+L+ + VQHREVQ ES F+ YF ++Y +GG
Sbjct: 62 HLWIGQQSSRDEQGACAVLAVHLNTLLGE-RPVQHREVQGNESDLFMSYFPRGLKYQEGG 120
Query: 364 HASGFSHVTINEGTE-KRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGE 540
S F + K+L+Q+KGK+N+R + ++S N GDCFILD+ IF + G
Sbjct: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGG 180
Query: 541 KAKGVERMKAITVANQIKDQDHNGRADIEVVDSEAHDGIFDRFFDALGSGNKEAIADAEE 720
K+ +ER KA +A I+D + G+A +E+V LG K A+ +
Sbjct: 181 KSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPA---EMIQVLGP--KPALKEGNP 235
Query: 721 GGDDQEFECVVTKEVSLSEISDKTGSIRITRL 816
+D + + +L ++SD TG + +T++
Sbjct: 236 -EEDLTADKANAQAAALYKVSDATGQMNLTKV 266
>BC014549-1|AAH14549.1| 348|Homo sapiens capping protein (actin
filament), gelsolin-like protein.
Length = 348
Score = 165 bits (402), Expect = 1e-40
Identities = 92/272 (33%), Positives = 150/272 (55%), Gaps = 1/272 (0%)
Frame = +1
Query: 4 MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 183
+P+ F + + PGL +WR+E +PV V + G+F+SGDSY+VL+ ++ +
Sbjct: 5 IPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEE---VSHL 61
Query: 184 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 363
H W+G ++S+DE GA A+L V+L+ + VQHREVQ ES F+ YF ++Y +GG
Sbjct: 62 HLWIGQQSSRDEQGACAVLAVHLNTLLGE-RPVQHREVQGNESDLFMSYFPRGLKYQEGG 120
Query: 364 HASGFSHVTINEGTE-KRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGE 540
S F + K+L+Q+KGK+N+R + ++S N GDCFILD+ IF + G
Sbjct: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGG 180
Query: 541 KAKGVERMKAITVANQIKDQDHNGRADIEVVDSEAHDGIFDRFFDALGSGNKEAIADAEE 720
K+ +ER KA +A I+D + G+A +E+V LG K A+ +
Sbjct: 181 KSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPA---EMIQVLGP--KPALKEGNP 235
Query: 721 GGDDQEFECVVTKEVSLSEISDKTGSIRITRL 816
+D + + +L ++SD TG + +T++
Sbjct: 236 -EEDLTADKANAQAAALYKVSDATGQMNLTKV 266
>BC000728-1|AAH00728.1| 348|Homo sapiens capping protein (actin
filament), gelsolin-like protein.
Length = 348
Score = 165 bits (402), Expect = 1e-40
Identities = 92/272 (33%), Positives = 150/272 (55%), Gaps = 1/272 (0%)
Frame = +1
Query: 4 MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 183
+P+ F + + PGL +WR+E +PV V + G+F+SGDSY+VL+ ++ +
Sbjct: 5 IPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEE---VSHL 61
Query: 184 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 363
H W+G ++S+DE GA A+L V+L+ + VQHREVQ ES F+ YF ++Y +GG
Sbjct: 62 HLWIGQQSSRDEQGACAVLAVHLNTLLGE-RPVQHREVQGNESDLFMSYFPRGLKYQEGG 120
Query: 364 HASGFSHVTINEGTE-KRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGE 540
S F + K+L+Q+KGK+N+R + ++S N GDCFILD+ IF + G
Sbjct: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGG 180
Query: 541 KAKGVERMKAITVANQIKDQDHNGRADIEVVDSEAHDGIFDRFFDALGSGNKEAIADAEE 720
K+ +ER KA +A I+D + G+A +E+V LG K A+ +
Sbjct: 181 KSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPA---EMIQVLGP--KPALKEGNP 235
Query: 721 GGDDQEFECVVTKEVSLSEISDKTGSIRITRL 816
+D + + +L ++SD TG + +T++
Sbjct: 236 -EEDLTADKANAQAAALYKVSDATGQMNLTKV 266
>AC062037-3|AAY24128.1| 348|Homo sapiens unknown protein.
Length = 348
Score = 165 bits (402), Expect = 1e-40
Identities = 92/272 (33%), Positives = 150/272 (55%), Gaps = 1/272 (0%)
Frame = +1
Query: 4 MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 183
+P+ F + + PGL +WR+E +PV V + G+F+SGDSY+VL+ ++ +
Sbjct: 5 IPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEE---VSHL 61
Query: 184 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 363
H W+G ++S+DE GA A+L V+L+ + VQHREVQ ES F+ YF ++Y +GG
Sbjct: 62 HLWIGQQSSRDEQGACAVLAVHLNTLLGE-RPVQHREVQGNESDLFMSYFPRGLKYQEGG 120
Query: 364 HASGFSHVTINEGTE-KRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGE 540
S F + K+L+Q+KGK+N+R + ++S N GDCFILD+ IF + G
Sbjct: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGG 180
Query: 541 KAKGVERMKAITVANQIKDQDHNGRADIEVVDSEAHDGIFDRFFDALGSGNKEAIADAEE 720
K+ +ER KA +A I+D + G+A +E+V LG K A+ +
Sbjct: 181 KSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPA---EMIQVLGP--KPALKEGNP 235
Query: 721 GGDDQEFECVVTKEVSLSEISDKTGSIRITRL 816
+D + + +L ++SD TG + +T++
Sbjct: 236 -EEDLTADKANAQAAALYKVSDATGQMNLTKV 266
>U12026-1|AAA92670.1| 172|Homo sapiens Cap-G protein.
Length = 172
Score = 133 bits (321), Expect = 8e-31
Identities = 66/170 (38%), Positives = 102/170 (60%), Gaps = 1/170 (0%)
Frame = +1
Query: 4 MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 183
+P+ F + + PGL +WR+E +PV V + G+F+SGDSY+VL+ ++ +
Sbjct: 5 IPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEE---VSHL 61
Query: 184 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 363
H W+G ++S+DE GA A+L V+L + VQHREVQ ES F+ YF ++Y +GG
Sbjct: 62 HLWIGQQSSRDEQGACAVLAVHL-NTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG 120
Query: 364 HASGFSHVTIN-EGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDV 510
S F + K+L+Q+KGK+N+R + ++S N GDCFILD+
Sbjct: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDL 170
>U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein.
Length = 1269
Score = 126 bits (303), Expect = 1e-28
Identities = 78/225 (34%), Positives = 119/225 (52%), Gaps = 2/225 (0%)
Frame = +1
Query: 31 DAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNT-TGDKDRLTWDIHFWLGSRT 207
D G+ PGL IW+IENF PV V + G FY D YIVL T D L W+I++W+G
Sbjct: 494 DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 553
Query: 208 SQDEAGAAAILTVNLDDEQFQGSAVQH-REVQYYESKEFLEYFSPAIRYLKGGHASGFSH 384
+ D+ +AI VNL + G+ + RE ES+EFL+ F I Y++GG ASGF +
Sbjct: 554 TLDKKACSAIHAVNL--RNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGF-Y 610
Query: 385 VTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERM 564
+ R++++ GK+N++++ V SL+ F+LD I+V+ G +A
Sbjct: 611 TVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTT 670
Query: 565 KAITVANQIKDQDHNGRADIEVVDSEAHDGIFDRFFDALGSGNKE 699
KA A +I + G+A+I ++ F++ALG E
Sbjct: 671 KARLFAEKINKNERKGKAEITLL---VQGQELPEFWEALGGEPSE 712
>U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog protein.
Length = 1268
Score = 126 bits (303), Expect = 1e-28
Identities = 78/225 (34%), Positives = 119/225 (52%), Gaps = 2/225 (0%)
Frame = +1
Query: 31 DAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNT-TGDKDRLTWDIHFWLGSRT 207
D G+ PGL IW+IENF PV V + G FY D YIVL T D L W+I++W+G
Sbjct: 493 DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 552
Query: 208 SQDEAGAAAILTVNLDDEQFQGSAVQH-REVQYYESKEFLEYFSPAIRYLKGGHASGFSH 384
+ D+ +AI VNL + G+ + RE ES+EFL+ F I Y++GG ASGF +
Sbjct: 553 TLDKKACSAIHAVNL--RNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGF-Y 609
Query: 385 VTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERM 564
+ R++++ GK+N++++ V SL+ F+LD I+V+ G +A
Sbjct: 610 TVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTT 669
Query: 565 KAITVANQIKDQDHNGRADIEVVDSEAHDGIFDRFFDALGSGNKE 699
KA A +I + G+A+I ++ F++ALG E
Sbjct: 670 KARLFAEKINKNERKGKAEITLL---VQGQELPEFWEALGGEPSE 711
>BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog
(Drosophila) protein.
Length = 1269
Score = 126 bits (303), Expect = 1e-28
Identities = 78/225 (34%), Positives = 119/225 (52%), Gaps = 2/225 (0%)
Frame = +1
Query: 31 DAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNT-TGDKDRLTWDIHFWLGSRT 207
D G+ PGL IW+IENF PV V + G FY D YIVL T D L W+I++W+G
Sbjct: 494 DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 553
Query: 208 SQDEAGAAAILTVNLDDEQFQGSAVQH-REVQYYESKEFLEYFSPAIRYLKGGHASGFSH 384
+ D+ +AI VNL + G+ + RE ES+EFL+ F I Y++GG ASGF +
Sbjct: 554 TLDKKACSAIHAVNL--RNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGF-Y 610
Query: 385 VTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERM 564
+ R++++ GK+N++++ V SL+ F+LD I+V+ G +A
Sbjct: 611 TVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTT 670
Query: 565 KAITVANQIKDQDHNGRADIEVVDSEAHDGIFDRFFDALGSGNKE 699
KA A +I + G+A+I ++ F++ALG E
Sbjct: 671 KARLFAEKINKNERKGKAEITLL---VQGQELPEFWEALGGEPSE 712
>AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog variant
protein.
Length = 1101
Score = 126 bits (303), Expect = 1e-28
Identities = 78/225 (34%), Positives = 119/225 (52%), Gaps = 2/225 (0%)
Frame = +1
Query: 31 DAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNT-TGDKDRLTWDIHFWLGSRT 207
D G+ PGL IW+IENF PV V + G FY D YIVL T D L W+I++W+G
Sbjct: 481 DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 540
Query: 208 SQDEAGAAAILTVNLDDEQFQGSAVQH-REVQYYESKEFLEYFSPAIRYLKGGHASGFSH 384
+ D+ +AI VNL + G+ + RE ES+EFL+ F I Y++GG ASGF +
Sbjct: 541 TLDKKACSAIHAVNL--RNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGF-Y 597
Query: 385 VTINEGTEKRLFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERM 564
+ R++++ GK+N++++ V SL+ F+LD I+V+ G +A
Sbjct: 598 TVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTT 657
Query: 565 KAITVANQIKDQDHNGRADIEVVDSEAHDGIFDRFFDALGSGNKE 699
KA A +I + G+A+I ++ F++ALG E
Sbjct: 658 KARLFAEKINKNERKGKAEITLL---VQGQELPEFWEALGGEPSE 699
>AL513122-7|CAI14416.1| 485|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 485
Score = 93.5 bits (222), Expect = 8e-19
Identities = 73/214 (34%), Positives = 103/214 (48%), Gaps = 4/214 (1%)
Frame = +1
Query: 55 EIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAAA 234
+IWRIE V V +G FY GDSYI+L R I+ W G++++QDE A+A
Sbjct: 179 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASA 238
Query: 235 ILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYLKGGHASGFSHVTINEGTE 408
ILT L DE+ G+ VQ R VQ E + F P I Y KGG S T T
Sbjct: 239 ILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIY-KGG-TSREGGQTAPAST- 294
Query: 409 KRLFQIKGKR--NVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVA 582
RLFQ++ R +V P +LN+ D F+L +++VG A E+ A +
Sbjct: 295 -RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELL 353
Query: 583 NQIKDQDHNGRADIEVVDSEAHDGIFDRFFDALG 684
++ Q ++V + DG F++ALG
Sbjct: 354 RVLRAQ------PVQVAEGSEPDG----FWEALG 377
>AK075198-1|BAC11465.1| 396|Homo sapiens protein ( Homo sapiens
cDNA FLJ90717 fis, clone PLACE1008657, highly similar to
Bovine mRNA for adseverin. ).
Length = 396
Score = 78.2 bits (184), Expect = 3e-14
Identities = 67/205 (32%), Positives = 97/205 (47%), Gaps = 7/205 (3%)
Frame = +1
Query: 1 KMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWD 180
+M H D K +EIWR+EN + V + +G FY GD YI+L T + ++
Sbjct: 64 QMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI--- 117
Query: 181 IHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYL 354
I+ W G+ ++DE +A LTV L D G AVQ R Q E L F P I Y
Sbjct: 118 IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYK 176
Query: 355 KGGHASGFSHVTINEGTEKRLFQIKGKRNV----RVKQVKPTFESLNNGDCFILDV-DHQ 519
G G RLFQ+ +RN+ R+ +V SLN+ D F+L + +
Sbjct: 177 NGTSKKGGQ----APAPPTRLFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLPQNS 230
Query: 520 IFVFVGEKAKGVERMKAITVANQIK 594
+++VG+ A E A VA+ +K
Sbjct: 231 GYIWVGKGASQEEEKGAEYVASVLK 255
Score = 35.1 bits (77), Expect = 0.31
Identities = 16/50 (32%), Positives = 28/50 (56%)
Frame = +1
Query: 466 TFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 615
T + L D +LD QIF+++G+ A VE+ +++ A + D +GR
Sbjct: 317 TQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGR 366
>AK027778-1|BAB55361.1| 468|Homo sapiens protein ( Homo sapiens
cDNA FLJ14872 fis, clone PLACE1002655, highly similar to
ADSEVERIN. ).
Length = 468
Score = 78.2 bits (184), Expect = 3e-14
Identities = 67/205 (32%), Positives = 97/205 (47%), Gaps = 7/205 (3%)
Frame = +1
Query: 1 KMPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWD 180
+M H D K +EIWR+EN + V + +G FY GD YI+L T + ++
Sbjct: 136 QMAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI--- 189
Query: 181 IHFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYL 354
I+ W G+ ++DE +A LTV L D G AVQ R Q E L F P I Y
Sbjct: 190 IYTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYK 248
Query: 355 KGGHASGFSHVTINEGTEKRLFQIKGKRNV----RVKQVKPTFESLNNGDCFILDV-DHQ 519
G G RLFQ+ +RN+ R+ +V SLN+ D F+L + +
Sbjct: 249 NGTSKKGGQ----APAPPTRLFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLPQNS 302
Query: 520 IFVFVGEKAKGVERMKAITVANQIK 594
+++VG+ A E A VA+ +K
Sbjct: 303 GYIWVGKGASQEEEKGAEYVASVLK 327
Score = 35.1 bits (77), Expect = 0.31
Identities = 16/50 (32%), Positives = 28/50 (56%)
Frame = +1
Query: 466 TFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 615
T + L D +LD QIF+++G+ A VE+ +++ A + D +GR
Sbjct: 389 TQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGR 438
>BC075797-1|AAH75797.1| 85|Homo sapiens Unknown (protein for
MGC:87550) protein.
Length = 85
Score = 72.5 bits (170), Expect = 2e-12
Identities = 30/61 (49%), Positives = 42/61 (68%)
Frame = +1
Query: 16 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 195
H+ FA AG++ GL++WRIE E V VP++ G FY GD+Y+VL+T T+ +HFWL
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWL 66
Query: 196 G 198
G
Sbjct: 67 G 67
>X07066-1|CAA30102.1| 69|Homo sapiens protein ( Human gene for
gelsolin exon 4. ).
Length = 69
Score = 71.3 bits (167), Expect = 4e-12
Identities = 28/62 (45%), Positives = 44/62 (70%), Gaps = 1/62 (1%)
Frame = +1
Query: 16 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 192
H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++ L +D+H+W
Sbjct: 8 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 67
Query: 193 LG 198
LG
Sbjct: 68 LG 69
>AL160060-2|CAH71300.1| 2214|Homo sapiens supervillin protein.
Length = 2214
Score = 59.3 bits (137), Expect(2) = 9e-09
Identities = 39/128 (30%), Positives = 68/128 (53%), Gaps = 4/128 (3%)
Frame = +1
Query: 415 LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIK 594
L QIKG+R+V+ + V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
Query: 595 DQDHNG-RAD-IEVVDS--EAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFECVVTKE 762
+ G RA I+ ++ H F+ L G + + A + +D+ +E + +
Sbjct: 1505 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLL--GGQTSYQSAGDPKEDELYEAAIIET 1562
Query: 763 VSLSEISD 786
+ + D
Sbjct: 1563 NCIYRLMD 1570
Score = 52.4 bits (120), Expect = 2e-06
Identities = 62/241 (25%), Positives = 111/241 (46%), Gaps = 24/241 (9%)
Frame = +1
Query: 52 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 186
+++W I F+ +PK G F+ GD+Y+V G + + +
Sbjct: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813
Query: 187 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 363
FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F +
Sbjct: 1814 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1865
Query: 364 HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 531
H+ N +E RL+ ++G+ V + +V SL + +L+V+ I+++
Sbjct: 1866 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1925
Query: 532 VGEKAKGVERMKAITVANQIKDQ---DHNGRADIEVVDSEAHDGIFD-RFFDALGSGNKE 699
G KA+ + T AN+IK+Q + + +V E +G F+DALG +++
Sbjct: 1926 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRRDRK 1985
Query: 700 A 702
A
Sbjct: 1986 A 1986
Score = 20.6 bits (41), Expect(2) = 9e-09
Identities = 9/41 (21%), Positives = 20/41 (48%)
Frame = +1
Query: 193 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 315
L S++ ++ +VNL ++ SAV ++ + + K
Sbjct: 1409 LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1449
>AL158167-3|CAI15237.1| 2214|Homo sapiens supervillin protein.
Length = 2214
Score = 59.3 bits (137), Expect(2) = 9e-09
Identities = 39/128 (30%), Positives = 68/128 (53%), Gaps = 4/128 (3%)
Frame = +1
Query: 415 LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIK 594
L QIKG+R+V+ + V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
Query: 595 DQDHNG-RAD-IEVVDS--EAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFECVVTKE 762
+ G RA I+ ++ H F+ L G + + A + +D+ +E + +
Sbjct: 1505 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLL--GGQTSYQSAGDPKEDELYEAAIIET 1562
Query: 763 VSLSEISD 786
+ + D
Sbjct: 1563 NCIYRLMD 1570
Score = 52.4 bits (120), Expect = 2e-06
Identities = 62/241 (25%), Positives = 111/241 (46%), Gaps = 24/241 (9%)
Frame = +1
Query: 52 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 186
+++W I F+ +PK G F+ GD+Y+V G + + +
Sbjct: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813
Query: 187 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 363
FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F +
Sbjct: 1814 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1865
Query: 364 HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 531
H+ N +E RL+ ++G+ V + +V SL + +L+V+ I+++
Sbjct: 1866 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1925
Query: 532 VGEKAKGVERMKAITVANQIKDQ---DHNGRADIEVVDSEAHDGIFD-RFFDALGSGNKE 699
G KA+ + T AN+IK+Q + + +V E +G F+DALG +++
Sbjct: 1926 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRRDRK 1985
Query: 700 A 702
A
Sbjct: 1986 A 1986
Score = 20.6 bits (41), Expect(2) = 9e-09
Identities = 9/41 (21%), Positives = 20/41 (48%)
Frame = +1
Query: 193 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 315
L S++ ++ +VNL ++ SAV ++ + + K
Sbjct: 1409 LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1449
>AF109135-1|AAD14682.1| 2214|Homo sapiens archvillin protein.
Length = 2214
Score = 59.3 bits (137), Expect(2) = 9e-09
Identities = 39/128 (30%), Positives = 68/128 (53%), Gaps = 4/128 (3%)
Frame = +1
Query: 415 LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIK 594
L QIKG+R+V+ + V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
Query: 595 DQDHNG-RAD-IEVVDS--EAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFECVVTKE 762
+ G RA I+ ++ H F+ L G + + A + +D+ +E + +
Sbjct: 1505 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLL--GGQTSYQSAGDPKEDELYEAAIIET 1562
Query: 763 VSLSEISD 786
+ + D
Sbjct: 1563 NCIYRLMD 1570
Score = 52.4 bits (120), Expect = 2e-06
Identities = 62/241 (25%), Positives = 111/241 (46%), Gaps = 24/241 (9%)
Frame = +1
Query: 52 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 186
+++W I F+ +PK G F+ GD+Y+V G + + +
Sbjct: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813
Query: 187 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 363
FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F +
Sbjct: 1814 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1865
Query: 364 HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 531
H+ N +E RL+ ++G+ V + +V SL + +L+V+ I+++
Sbjct: 1866 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1925
Query: 532 VGEKAKGVERMKAITVANQIKDQ---DHNGRADIEVVDSEAHDGIFD-RFFDALGSGNKE 699
G KA+ + T AN+IK+Q + + +V E +G F+DALG +++
Sbjct: 1926 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRRDRK 1985
Query: 700 A 702
A
Sbjct: 1986 A 1986
Score = 20.6 bits (41), Expect(2) = 9e-09
Identities = 9/41 (21%), Positives = 20/41 (48%)
Frame = +1
Query: 193 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 315
L S++ ++ +VNL ++ SAV ++ + + K
Sbjct: 1409 LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1449
>AL160060-1|CAH71301.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 59.3 bits (137), Expect(2) = 9e-09
Identities = 39/128 (30%), Positives = 68/128 (53%), Gaps = 4/128 (3%)
Frame = +1
Query: 415 LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIK 594
L QIKG+R+V+ + V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 595 DQDHNG-RAD-IEVVDS--EAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFECVVTKE 762
+ G RA I+ ++ H F+ L G + + A + +D+ +E + +
Sbjct: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLL--GGQTSYQSAGDPKEDELYEAAIIET 1136
Query: 763 VSLSEISD 786
+ + D
Sbjct: 1137 NCIYRLMD 1144
Score = 52.4 bits (120), Expect = 2e-06
Identities = 62/241 (25%), Positives = 111/241 (46%), Gaps = 24/241 (9%)
Frame = +1
Query: 52 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 186
+++W I F+ +PK G F+ GD+Y+V G + + +
Sbjct: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387
Query: 187 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 363
FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F +
Sbjct: 1388 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1439
Query: 364 HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 531
H+ N +E RL+ ++G+ V + +V SL + +L+V+ I+++
Sbjct: 1440 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1499
Query: 532 VGEKAKGVERMKAITVANQIKDQ---DHNGRADIEVVDSEAHDGIFD-RFFDALGSGNKE 699
G KA+ + T AN+IK+Q + + +V E +G F+DALG +++
Sbjct: 1500 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRRDRK 1559
Query: 700 A 702
A
Sbjct: 1560 A 1560
Score = 20.6 bits (41), Expect(2) = 9e-09
Identities = 9/41 (21%), Positives = 20/41 (48%)
Frame = +1
Query: 193 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 315
L S++ ++ +VNL ++ SAV ++ + + K
Sbjct: 983 LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1023
>AL158167-2|CAI15236.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 59.3 bits (137), Expect(2) = 9e-09
Identities = 39/128 (30%), Positives = 68/128 (53%), Gaps = 4/128 (3%)
Frame = +1
Query: 415 LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIK 594
L QIKG+R+V+ + V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 595 DQDHNG-RAD-IEVVDS--EAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFECVVTKE 762
+ G RA I+ ++ H F+ L G + + A + +D+ +E + +
Sbjct: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLL--GGQTSYQSAGDPKEDELYEAAIIET 1136
Query: 763 VSLSEISD 786
+ + D
Sbjct: 1137 NCIYRLMD 1144
Score = 52.4 bits (120), Expect = 2e-06
Identities = 62/241 (25%), Positives = 111/241 (46%), Gaps = 24/241 (9%)
Frame = +1
Query: 52 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 186
+++W I F+ +PK G F+ GD+Y+V G + + +
Sbjct: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387
Query: 187 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 363
FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F +
Sbjct: 1388 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1439
Query: 364 HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 531
H+ N +E RL+ ++G+ V + +V SL + +L+V+ I+++
Sbjct: 1440 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1499
Query: 532 VGEKAKGVERMKAITVANQIKDQ---DHNGRADIEVVDSEAHDGIFD-RFFDALGSGNKE 699
G KA+ + T AN+IK+Q + + +V E +G F+DALG +++
Sbjct: 1500 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRRDRK 1559
Query: 700 A 702
A
Sbjct: 1560 A 1560
Score = 20.6 bits (41), Expect(2) = 9e-09
Identities = 9/41 (21%), Positives = 20/41 (48%)
Frame = +1
Query: 193 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 315
L S++ ++ +VNL ++ SAV ++ + + K
Sbjct: 983 LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1023
>AF051851-1|AAC64696.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 59.3 bits (137), Expect(2) = 9e-09
Identities = 39/128 (30%), Positives = 68/128 (53%), Gaps = 4/128 (3%)
Frame = +1
Query: 415 LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIK 594
L QIKG+R+V+ + V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 595 DQDHNG-RAD-IEVVDS--EAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFECVVTKE 762
+ G RA I+ ++ H F+ L G + + A + +D+ +E + +
Sbjct: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLL--GGQTSYQSAGDPKEDELYEAAIIET 1136
Query: 763 VSLSEISD 786
+ + D
Sbjct: 1137 NCIYRLMD 1144
Score = 52.4 bits (120), Expect = 2e-06
Identities = 62/241 (25%), Positives = 111/241 (46%), Gaps = 24/241 (9%)
Frame = +1
Query: 52 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 186
+++W I F+ +PK G F+ GD+Y+V G + + +
Sbjct: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387
Query: 187 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 363
FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F +
Sbjct: 1388 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1439
Query: 364 HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 531
H+ N +E RL+ ++G+ V + +V SL + +L+V+ I+++
Sbjct: 1440 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1499
Query: 532 VGEKAKGVERMKAITVANQIKDQ---DHNGRADIEVVDSEAHDGIFD-RFFDALGSGNKE 699
G KA+ + T AN+IK+Q + + +V E +G F+DALG +++
Sbjct: 1500 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRRDRK 1559
Query: 700 A 702
A
Sbjct: 1560 A 1560
Score = 20.6 bits (41), Expect(2) = 9e-09
Identities = 9/41 (21%), Positives = 20/41 (48%)
Frame = +1
Query: 193 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 315
L S++ ++ +VNL ++ SAV ++ + + K
Sbjct: 983 LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1023
>AF051850-1|AAC64695.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 59.3 bits (137), Expect(2) = 9e-09
Identities = 39/128 (30%), Positives = 68/128 (53%), Gaps = 4/128 (3%)
Frame = +1
Query: 415 LFQIKGKRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIK 594
L QIKG+R+V+ + V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 595 DQDHNG-RAD-IEVVDS--EAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFECVVTKE 762
+ G RA I+ ++ H F+ L G + + A + +D+ +E + +
Sbjct: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLL--GGQTSYQSAGDPKEDELYEAAIIET 1136
Query: 763 VSLSEISD 786
+ + D
Sbjct: 1137 NCIYRLMD 1144
Score = 52.4 bits (120), Expect = 2e-06
Identities = 62/241 (25%), Positives = 111/241 (46%), Gaps = 24/241 (9%)
Frame = +1
Query: 52 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVL------NTTGDKDRLTWDIH--------- 186
+++W I F+ +PK G F+ GD+Y+V G + + +
Sbjct: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387
Query: 187 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLKGG 363
FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F +
Sbjct: 1388 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCFQGGMVV---- 1439
Query: 364 HASGFSHVTINEGTEKRLFQIKGKRNV--RVKQVKPTFESL-NNGDCFILDVDHQ-IFVF 531
H+ N +E RL+ ++G+ V + +V SL + +L+V+ I+++
Sbjct: 1440 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1499
Query: 532 VGEKAKGVERMKAITVANQIKDQ---DHNGRADIEVVDSEAHDGIFD-RFFDALGSGNKE 699
G KA+ + T AN+IK+Q + + +V E +G F+DALG +++
Sbjct: 1500 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRRDRK 1559
Query: 700 A 702
A
Sbjct: 1560 A 1560
Score = 20.6 bits (41), Expect(2) = 9e-09
Identities = 9/41 (21%), Positives = 20/41 (48%)
Frame = +1
Query: 193 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESK 315
L S++ ++ +VNL ++ SAV ++ + + K
Sbjct: 983 LAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1023
>D88154-1|BAA21668.1| 686|Homo sapiens villin-like protein protein.
Length = 686
Score = 59.7 bits (138), Expect = 1e-08
Identities = 50/185 (27%), Positives = 77/185 (41%), Gaps = 5/185 (2%)
Frame = +1
Query: 52 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAA 231
+E+W I++ V + G +G+ Y+VL T R+ + ++ W G + + DE A
Sbjct: 223 VEVWCIQDLHRQPVDPKRHGQLCAGNCYLVLYTYQRLGRVQYILYLWQGHQATADEIEAL 282
Query: 232 AILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLK---GGHASGFSHVTINEG 402
L D + G VQ E FL F + + G H G S T
Sbjct: 283 NSNAEEL-DVMYGGVLVQEHVTMGSEPPHFLAIFQGQLVIFQERAGHHGKGQSAST---- 337
Query: 403 TEKRLFQIKG--KRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAIT 576
RLFQ++G N R +V SLN+ D F+L +++ G+ G +R A
Sbjct: 338 --TRLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTASVCYLWFGKGCNGDQREMARV 395
Query: 577 VANQI 591
V I
Sbjct: 396 VVTVI 400
>BC004300-1|AAH04300.1| 672|Homo sapiens VILL protein protein.
Length = 672
Score = 59.7 bits (138), Expect = 1e-08
Identities = 50/185 (27%), Positives = 77/185 (41%), Gaps = 5/185 (2%)
Frame = +1
Query: 52 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAA 231
+E+W I++ V + G +G+ Y+VL T R+ + ++ W G + + DE A
Sbjct: 209 VEVWCIQDLHRQPVDPKRHGQLCAGNCYLVLYTYQRLGRVQYILYLWQGHQATADEIEAL 268
Query: 232 AILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLK---GGHASGFSHVTINEG 402
L D + G VQ E FL F + + G H G S T
Sbjct: 269 NSNAEEL-DVMYGGVLVQEHVTMGSEPPHFLAIFQGQLVIFQERAGHHGKGQSAST---- 323
Query: 403 TEKRLFQIKG--KRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAIT 576
RLFQ++G N R +V SLN+ D F+L +++ G+ G +R A
Sbjct: 324 --TRLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTASVCYLWFGKGCNGDQREMARV 381
Query: 577 VANQI 591
V I
Sbjct: 382 VVTVI 386
>BC000243-1|AAH00243.1| 686|Homo sapiens VILL protein protein.
Length = 686
Score = 59.7 bits (138), Expect = 1e-08
Identities = 50/185 (27%), Positives = 77/185 (41%), Gaps = 5/185 (2%)
Frame = +1
Query: 52 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAA 231
+E+W I++ V + G +G+ Y+VL T R+ + ++ W G + + DE A
Sbjct: 223 VEVWCIQDLHRQPVDPKRHGQLCAGNCYLVLYTYQRLGRVQYILYLWQGHQATADEIEAL 282
Query: 232 AILTVNLDDEQFQGSAVQHREVQYYESKEFLEYFSPAIRYLK---GGHASGFSHVTINEG 402
L D + G VQ E FL F + + G H G S T
Sbjct: 283 NSNAEEL-DVMYGGVLVQEHVTMGSEPPHFLAIFQGQLVIFQERAGHHGKGQSAST---- 337
Query: 403 TEKRLFQIKG--KRNVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAIT 576
RLFQ++G N R +V SLN+ D F+L +++ G+ G +R A
Sbjct: 338 --TRLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTASVCYLWFGKGCNGDQREMARV 395
Query: 577 VANQI 591
V I
Sbjct: 396 VVTVI 400
>BC017491-1|AAH17491.1| 285|Homo sapiens Similar to gelsolin
(amyloidosis, Finnish type) protein.
Length = 285
Score = 56.4 bits (130), Expect = 1e-07
Identities = 53/164 (32%), Positives = 77/164 (46%), Gaps = 4/164 (2%)
Frame = +1
Query: 205 TSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF--SPAIRYLKGGHASGF 378
++QDE A+AILT L DE+ G+ VQ R VQ E + F P I Y KGG S
Sbjct: 1 STQDEVAASAILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIY-KGG-TSRE 57
Query: 379 SHVTINEGTEKRLFQIKGKR--NVRVKQVKPTFESLNNGDCFILDVDHQIFVFVGEKAKG 552
T T RLFQ++ R +V P +LN+ D F+L +++VG A
Sbjct: 58 GGQTAPAST--RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASE 115
Query: 553 VERMKAITVANQIKDQDHNGRADIEVVDSEAHDGIFDRFFDALG 684
E+ A + ++ Q ++V + DG F++ALG
Sbjct: 116 AEKTGAQELLRVLRAQ------PVQVAEGSEPDG----FWEALG 149
Score = 32.3 bits (70), Expect = 2.2
Identities = 16/48 (33%), Positives = 27/48 (56%)
Frame = +1
Query: 472 ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 615
E L D +LD Q+FV+VG+ ++ E+ +A+T A + + D R
Sbjct: 194 EDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANR 241
>AK092426-1|BAC03887.1| 258|Homo sapiens protein ( Homo sapiens
cDNA FLJ35107 fis, clone PLACE6006871, moderately
similar to SUPPRESSOR PROTEIN SRP40. ).
Length = 258
Score = 37.5 bits (83), Expect = 0.058
Identities = 58/227 (25%), Positives = 91/227 (40%), Gaps = 5/227 (2%)
Frame = +2
Query: 38 AGSRVSKYGGLRTSNRSPFRRLSSV---SSTPGTPTLY*TPQAIRTV*HGTSISGSARGP 208
AG GG R+S+ S LSS SS P + + +P + + S S S+ P
Sbjct: 25 AGPNALGSGGSRSSSSSSRSILSSSILSSSIPSSSSSSSSPSSSHSS-SSPSSSHSSSSP 83
Query: 209 ARTKPARRPSSR*TWTTNNSRDQRYSTERSNITSPRSS*NISHQPSAI*KADTPQASAT* 388
+ + PSS + ++++S S+ S+ +SP SS + S S + +P +S++
Sbjct: 84 SSSSSTSSPSSSSSSSSSSSPSSSNSSSSSSSSSPSSS-SSSSSSSPSSSSSSPSSSSSS 142
Query: 389 RSMREQRNDSSRSRVKETSALSR*N-RHLSPXXXXXXXXXXXXIRSSSLWVRRRKESRG* 565
S + SS S +S+ S + SP SSS S
Sbjct: 143 SSSSPSSSSSSPSSSSSSSSSSSSSPSSSSPSSSGSSPSSSNSSPSSS---SSSPSSSSS 199
Query: 566 KPSP*PTR-LKTRITMEGPISKWLTPKRTMESSTGSSMPSAPATRRP 703
PSP + + + P + + SS SS PSA RRP
Sbjct: 200 SPSPRSSSPSSSSSSTSSPSTSSPSSSSPSSSSPSSSCPSAALGRRP 246
>BC117319-1|AAI17320.1| 257|Homo sapiens TPRXL protein protein.
Length = 257
Score = 35.1 bits (77), Expect = 0.31
Identities = 56/227 (24%), Positives = 90/227 (39%), Gaps = 5/227 (2%)
Frame = +2
Query: 38 AGSRVSKYGGLRTSNRSPFRRLSSV---SSTPGTPTLY*TPQAIRTV*HGTSISGSARGP 208
AG GG R+S+ S LSS SS P + + +P + + S S S+ P
Sbjct: 25 AGPNALGSGGSRSSSSSSRSILSSSILSSSIPSSSSSSSSPSSSHSS-SSPSSSHSSSSP 83
Query: 209 ARTKPARRPSSR*TWTTNNSRDQRYSTERSNITSPRSS*NISHQPSAI*KADTPQASAT* 388
+ + PSS + ++++ S+ S+ + SS + S PS+ + +P +S++
Sbjct: 84 SSSSSTSSPSSSSSSSSSSPSSSNSSSSSSSSSPSSSSSSSSSSPSS--SSSSPSSSSSS 141
Query: 389 RSMREQRNDSSRSRVKETSALSR*N-RHLSPXXXXXXXXXXXXIRSSSLWVRRRKESRG* 565
S + SS S +S+ S + SP SSS S
Sbjct: 142 SSSSPSSSSSSPSSSSSSSSSSSSSPSSSSPSSSGSSPSSSNSSPSSS---SSSPSSSSS 198
Query: 566 KPSP*PTR-LKTRITMEGPISKWLTPKRTMESSTGSSMPSAPATRRP 703
PSP + + + P + + SS SS PSA RRP
Sbjct: 199 SPSPRSSSPSSSSSSTSSPSTSSPSSSSPSSSSPSSSCPSAALGRRP 245
>AL513122-9|CAI14417.1| 207|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 207
Score = 32.3 bits (70), Expect = 2.2
Identities = 16/48 (33%), Positives = 27/48 (56%)
Frame = +1
Query: 472 ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR 615
E L D +LD Q+FV+VG+ ++ E+ +A+T A + + D R
Sbjct: 116 EDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANR 163
>Z37352-1|CAA85604.1| 124|Homo sapiens immunoglobulin lambda chain
variable region protein.
Length = 124
Score = 31.9 bits (69), Expect = 2.9
Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 3/77 (3%)
Frame = +1
Query: 598 QDHNGRADIEVV--DSEAHDGIFDRFFDALGSGNKEAIADAE-EGGDDQEFECVVTKEVS 768
Q G+A + V+ DSE G DRF ++ SGN+ + + E GD+ ++ C V E S
Sbjct: 36 QQKPGQAPVVVIYYDSERPSGTPDRFSGSI-SGNRATLTISRVEAGDEADYYCQVWDESS 94
Query: 769 LSEISDKTGSIRITRLP 819
+ + + R P
Sbjct: 95 DQVVFGGGTELTVLRQP 111
>BC106877-1|AAI06878.1| 663|Homo sapiens chromosome 1 open reading
frame 106 protein.
Length = 663
Score = 31.9 bits (69), Expect = 2.9
Identities = 22/69 (31%), Positives = 33/69 (47%)
Frame = -2
Query: 374 PEACPPFK*RMAGEKYSRNSLDS*YWTSRCCTADPWNCSSSKFTVRMAAAPASSWLVLEP 195
PEA P + + + SLD Y R +++PW+ SSS T ASS +LEP
Sbjct: 309 PEAGSPERAPVQNSPWKETSLDHPYEKPRK-SSEPWSESSSPATTPQDGPSASSLWLLEP 367
Query: 194 SQKWMSHVR 168
+ + +R
Sbjct: 368 ASYHVVPIR 376
>AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ
protein protein.
Length = 3222
Score = 31.9 bits (69), Expect = 2.9
Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 5/63 (7%)
Frame = +1
Query: 463 PTFESLNNGDCFILDVDHQ--IFV---FVGEKAKGVERMKAITVANQIKDQDHNGRADIE 627
P F S D +LDV+ IF F+ E + + K +TV+ KD NG+ D E
Sbjct: 945 PPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPRKILTVSAMDKDSGPNGQLDYE 1004
Query: 628 VVD 636
+V+
Sbjct: 1005 IVN 1007
>AK001763-1|BAA91892.1| 663|Homo sapiens protein ( Homo sapiens
cDNA FLJ10901 fis, clone NT2RP5003524. ).
Length = 663
Score = 31.9 bits (69), Expect = 2.9
Identities = 22/69 (31%), Positives = 33/69 (47%)
Frame = -2
Query: 374 PEACPPFK*RMAGEKYSRNSLDS*YWTSRCCTADPWNCSSSKFTVRMAAAPASSWLVLEP 195
PEA P + + + SLD Y R +++PW+ SSS T ASS +LEP
Sbjct: 309 PEAGSPERAPVQNSPWKETSLDHPYEKPRK-SSEPWSESSSPATTPQDGPSASSLWLLEP 367
Query: 194 SQKWMSHVR 168
+ + +R
Sbjct: 368 ASYHVVPIR 376
>AF063745-1|AAC16826.1| 109|Homo sapiens immunoglobulin lambda
light chain variable region protein.
Length = 109
Score = 31.1 bits (67), Expect = 5.1
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 3/89 (3%)
Frame = +1
Query: 496 FILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRADIEVV--DSEAHDGIFDRF 669
++L + V G+ A+ K I N Q G+A + VV DS+ GI +RF
Sbjct: 2 YVLTQPPSVSVAPGQTARITCEGKNIGSTNVHWYQQKPGQAPVLVVFADSDRPSGIPERF 61
Query: 670 FDALGSGNKEAIADAE-EGGDDQEFECVV 753
+ SGN + EGGD+ ++ C V
Sbjct: 62 SGS-NSGNTATLTITRVEGGDEADYYCQV 89
>U77456-1|AAC50870.1| 375|Homo sapiens nucleosome assembly protein
2 protein.
Length = 375
Score = 30.7 bits (66), Expect = 6.7
Identities = 18/61 (29%), Positives = 29/61 (47%), Gaps = 1/61 (1%)
Frame = +1
Query: 565 KAITVANQIKDQDHNGRADIEVVDSEAHDGIFDRFFDAL-GSGNKEAIADAEEGGDDQEF 741
K +TV K Q H GR + + + + F FF+ L SG+ E++ + E +F
Sbjct: 258 KNVTVKTIKKKQKHKGRGTVRTITKQVPNESFFNFFNPLKASGDGESLDEDSEFTLASDF 317
Query: 742 E 744
E
Sbjct: 318 E 318
>BC022090-1|AAH22090.1| 375|Homo sapiens nucleosome assembly
protein 1-like 4 protein.
Length = 375
Score = 30.7 bits (66), Expect = 6.7
Identities = 18/61 (29%), Positives = 29/61 (47%), Gaps = 1/61 (1%)
Frame = +1
Query: 565 KAITVANQIKDQDHNGRADIEVVDSEAHDGIFDRFFDAL-GSGNKEAIADAEEGGDDQEF 741
K +TV K Q H GR + + + + F FF+ L SG+ E++ + E +F
Sbjct: 258 KNVTVKTIKKKQKHKGRGTVRTITKQVPNESFFNFFNPLKASGDGESLDEDSEFTLASDF 317
Query: 742 E 744
E
Sbjct: 318 E 318
>D31661-1|BAA06506.1| 981|Homo sapiens tyrosine kinase precursor
protein.
Length = 981
Score = 30.3 bits (65), Expect = 8.8
Identities = 29/123 (23%), Positives = 56/123 (45%), Gaps = 4/123 (3%)
Frame = +1
Query: 292 EVQYYESKEFLEYFSPAIRYLKGGHASGFSHVTIN--EGTEKRLFQIKGKRNVRVKQV-- 459
E+QYYE +E EY + AI+ S + VT+ + +FQ++ + +
Sbjct: 464 ELQYYEKQELSEYNATAIK-------SPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSG 516
Query: 460 KPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRADIEVVDS 639
K F+++ D + + ++ + +G A G+ + A+ V + ++ RAD E D
Sbjct: 517 KMYFQTMTEAD-YQTSIQEKLPLIIGSSAAGLVFLIAVVVIAIVCNRRGFERADSEYTDK 575
Query: 640 EAH 648
H
Sbjct: 576 LQH 578
>AY307931-1|AAQ73825.1| 336|Homo sapiens intestinal mucin MUC3B
precursor protein.
Length = 336
Score = 30.3 bits (65), Expect = 8.8
Identities = 17/43 (39%), Positives = 25/43 (58%), Gaps = 1/43 (2%)
Frame = +2
Query: 569 PSP*PTRLKTRITMEGPISKWLTPKRTMES-STGSSMPSAPAT 694
P+P T LKT +T PI+ +T T+ S +T +S P+A T
Sbjct: 243 PTPVFTTLKTAVTSTSPITSTITSTNTVTSMTTTTSRPTATNT 285
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.317 0.136 0.397
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 120,742,351
Number of Sequences: 237096
Number of extensions: 2608936
Number of successful extensions: 11366
Number of sequences better than 10.0: 53
Number of HSP's better than 10.0 without gapping: 10643
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 11285
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10315140830
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
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