Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= e96h0944
(709 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 151 2e-35
UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 115 1e-24
UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 113 5e-24
UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 100 3e-20
UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 98 2e-19
UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 97 3e-19
UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 97 5e-19
UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 95 2e-18
UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 93 6e-18
UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 89 7e-17
UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 89 1e-16
UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 76 1e-16
UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 88 2e-16
UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 87 5e-16
UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 86 9e-16
UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 85 2e-15
UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 85 2e-15
UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 84 4e-15
UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 83 5e-15
UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 83 9e-15
UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 76 1e-14
UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 82 1e-14
UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 82 1e-14
UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 82 1e-14
UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 82 2e-14
UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 81 2e-14
UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 81 2e-14
UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 81 2e-14
UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 81 2e-14
UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 80 5e-14
UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 80 5e-14
UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 80 6e-14
UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 80 6e-14
UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 79 8e-14
UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 79 1e-13
UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 79 1e-13
UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 79 1e-13
UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 78 2e-13
UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 78 2e-13
UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 78 2e-13
UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 78 2e-13
UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 78 2e-13
UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 78 2e-13
UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 78 2e-13
UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 77 3e-13
UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 77 3e-13
UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 77 3e-13
UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 77 4e-13
UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 77 6e-13
UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 76 1e-12
UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc... 76 1e-12
UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 75 1e-12
UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 75 1e-12
UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 75 1e-12
UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 75 2e-12
UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 75 2e-12
UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 75 2e-12
UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 75 2e-12
UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 75 2e-12
UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 74 4e-12
UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 73 5e-12
UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 73 5e-12
UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 73 5e-12
UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 73 5e-12
UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 73 7e-12
UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 73 7e-12
UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 73 9e-12
UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 72 2e-11
UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 72 2e-11
UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 71 2e-11
UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 71 2e-11
UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 71 2e-11
UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 71 3e-11
UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 71 3e-11
UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 71 3e-11
UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 71 4e-11
UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 71 4e-11
UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 70 5e-11
UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 70 5e-11
UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 70 6e-11
UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 69 9e-11
UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 69 9e-11
UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 69 1e-10
UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 69 1e-10
UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 69 1e-10
UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 68 2e-10
UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 68 2e-10
UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 68 2e-10
UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 68 3e-10
UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 68 3e-10
UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 68 3e-10
UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 67 3e-10
UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 67 3e-10
UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 67 3e-10
UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 67 3e-10
UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 67 3e-10
UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 67 5e-10
UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 67 5e-10
UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 67 5e-10
UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 67 5e-10
UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 66 6e-10
UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 66 8e-10
UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 66 8e-10
UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 66 8e-10
UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 66 8e-10
UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap... 66 8e-10
UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 66 1e-09
UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 65 1e-09
UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 65 1e-09
UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 65 1e-09
UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 65 1e-09
UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 65 1e-09
UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;... 65 2e-09
UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 65 2e-09
UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 65 2e-09
UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 65 2e-09
UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 65 2e-09
UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 64 2e-09
UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 64 2e-09
UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 64 2e-09
UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 64 3e-09
UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 64 3e-09
UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 64 4e-09
UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 64 4e-09
UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 64 4e-09
UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 64 4e-09
UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 63 6e-09
UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 63 6e-09
UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 63 6e-09
UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 63 7e-09
UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 63 7e-09
UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 63 7e-09
UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 62 1e-08
UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 62 1e-08
UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 62 1e-08
UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 62 1e-08
UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 62 1e-08
UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 62 2e-08
UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 61 2e-08
UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 61 2e-08
UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 61 2e-08
UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 61 2e-08
UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 61 2e-08
UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 61 2e-08
UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 61 3e-08
UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 61 3e-08
UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 61 3e-08
UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 60 4e-08
UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 60 4e-08
UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 60 5e-08
UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 60 5e-08
UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 60 7e-08
UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 60 7e-08
UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 60 7e-08
UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 60 7e-08
UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 59 9e-08
UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 59 9e-08
UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 59 9e-08
UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 59 9e-08
UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 59 1e-07
UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 59 1e-07
UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 58 2e-07
UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 58 2e-07
UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 58 2e-07
UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 58 2e-07
UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 58 2e-07
UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 58 2e-07
UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 58 3e-07
UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 58 3e-07
UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 58 3e-07
UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 58 3e-07
UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 57 4e-07
UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 57 4e-07
UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 57 4e-07
UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 57 5e-07
UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 57 5e-07
UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 56 6e-07
UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 56 6e-07
UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 56 6e-07
UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 56 6e-07
UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 56 6e-07
UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 56 6e-07
UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 56 9e-07
UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 56 9e-07
UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 56 9e-07
UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 56 9e-07
UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 56 1e-06
UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 56 1e-06
UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 56 1e-06
UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 56 1e-06
UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 55 1e-06
UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 55 1e-06
UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 55 1e-06
UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 55 2e-06
UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 54 3e-06
UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 54 3e-06
UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 54 3e-06
UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 54 3e-06
UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 54 3e-06
UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 54 5e-06
UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 54 5e-06
UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 46 5e-06
UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 53 6e-06
UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 53 6e-06
UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 53 6e-06
UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 53 8e-06
UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 53 8e-06
UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 53 8e-06
UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 52 1e-05
UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 52 1e-05
UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 52 2e-05
UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 52 2e-05
UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05
UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 51 2e-05
UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 51 2e-05
UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 51 2e-05
UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 51 3e-05
UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 51 3e-05
UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 51 3e-05
UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 50 4e-05
UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 50 4e-05
UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 50 4e-05
UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 50 4e-05
UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 50 6e-05
UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 50 6e-05
UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 50 6e-05
UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 50 7e-05
UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 50 7e-05
UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 50 7e-05
UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ... 50 7e-05
UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ... 50 7e-05
UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 50 7e-05
UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 50 7e-05
UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 50 7e-05
UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ... 49 1e-04
UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 49 1e-04
UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 49 1e-04
UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 49 1e-04
UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 49 1e-04
UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 49 1e-04
UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 49 1e-04
UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 49 1e-04
UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 49 1e-04
UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 48 2e-04
UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 48 2e-04
UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 48 2e-04
UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 48 2e-04
UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 48 3e-04
UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 48 3e-04
UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 48 3e-04
UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 48 3e-04
UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 48 3e-04
UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 47 4e-04
UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 47 4e-04
UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 47 5e-04
UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 47 5e-04
UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 47 5e-04
UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 47 5e-04
UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 47 5e-04
UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 46 7e-04
UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 46 7e-04
UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 46 7e-04
UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 46 7e-04
UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 46 7e-04
UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 46 0.001
UniRef50_A2WWZ1 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001
UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei... 46 0.001
UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 46 0.001
UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 46 0.001
UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3.... 46 0.001
UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 46 0.001
UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 46 0.001
UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 45 0.002
UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 45 0.002
UniRef50_P49261 Cluster: Rho beta-crystallin; n=1; Lepidodactylu... 45 0.002
UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 45 0.002
UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 45 0.002
UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 45 0.002
UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 45 0.002
UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 45 0.002
UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase... 44 0.003
UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 44 0.003
UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ... 44 0.003
UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 44 0.003
UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 44 0.003
UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 44 0.003
UniRef50_UPI0000447325 Cluster: PREDICTED: similar to aldo-keto ... 44 0.004
UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel... 44 0.004
UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 44 0.004
UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 44 0.005
UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter... 44 0.005
UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular... 44 0.005
UniRef50_Q4HND9 Cluster: Oxidoreductase, aldo/keto reductase fam... 44 0.005
UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 44 0.005
UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 44 0.005
UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 44 0.005
UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 44 0.005
UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto... 43 0.006
UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 43 0.006
UniRef50_A0Q648 Cluster: Aldo/keto reductase family protein; n=1... 43 0.006
UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 43 0.006
UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|... 43 0.006
UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 43 0.009
UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 43 0.009
UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 43 0.009
UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 43 0.009
UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 43 0.009
UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 43 0.009
UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 42 0.011
UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ... 42 0.011
UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 42 0.011
UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 42 0.011
UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 42 0.015
UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 42 0.015
UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 42 0.015
UniRef50_P0A9T5 Cluster: Protein tas; n=88; Bacteria|Rep: Protei... 42 0.015
UniRef50_Q837G5 Cluster: Oxidoreductase, aldo/keto reductase 2 f... 42 0.020
UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 41 0.026
UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 41 0.026
UniRef50_P77256 Cluster: Uncharacterized oxidoreductase ydjG; n=... 41 0.026
UniRef50_P80874 Cluster: General stress protein 69; n=16; cellul... 41 0.026
UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 41 0.034
UniRef50_A0Y7Y8 Cluster: Aldo/keto reductase; n=1; marine gamma ... 41 0.034
UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep... 40 0.045
UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 40 0.045
UniRef50_A1ZPI5 Cluster: Oxidoreductase; n=1; Microscilla marina... 40 0.045
UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 40 0.045
UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 40 0.045
UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 40 0.060
UniRef50_A0ZMD5 Cluster: Tas; n=1; Nodularia spumigena CCY 9414|... 40 0.060
UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 40 0.060
UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ... 40 0.060
UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 40 0.060
UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 40 0.079
UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 40 0.079
UniRef50_Q0LKQ4 Cluster: Aldo/keto reductase; n=1; Herpetosiphon... 40 0.079
UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;... 40 0.079
UniRef50_Q8F4Y9 Cluster: Aldo/keto reductase family protein; n=4... 31 0.084
UniRef50_Q8EZ83 Cluster: Aldo/keto reductase family protein; n=1... 39 0.10
UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|... 39 0.10
UniRef50_Q2SL81 Cluster: Predicted oxidoreductase; n=10; Bacteri... 39 0.10
UniRef50_Q12D62 Cluster: Aldo/keto reductase; n=12; Proteobacter... 39 0.10
UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 39 0.10
UniRef50_A6VXU3 Cluster: Aldo/keto reductase; n=14; Proteobacter... 39 0.10
UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 39 0.10
UniRef50_P77735 Cluster: Uncharacterized oxidoreductase yajO; n=... 39 0.10
UniRef50_Q2FGN2 Cluster: Oxidoreductase, aldo/keto reductase fam... 39 0.14
UniRef50_Q1EZH4 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 39 0.14
UniRef50_A6WAE5 Cluster: Aldo/keto reductase; n=1; Kineococcus r... 39 0.14
UniRef50_A5FAZ9 Cluster: Aldo/keto reductase; n=1; Flavobacteriu... 39 0.14
UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga... 39 0.14
UniRef50_A1GCG3 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 39 0.14
UniRef50_A0QWF1 Cluster: Aldo/keto reductase; n=1; Mycobacterium... 39 0.14
UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact... 39 0.14
UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 39 0.14
UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ... 39 0.14
UniRef50_A6X3I0 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 38 0.18
UniRef50_A6EEC4 Cluster: Putative Norsolorinic acid reductase; n... 38 0.18
UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 38 0.18
UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 38 0.18
UniRef50_Q97UJ7 Cluster: Oxidoreductase; n=4; Archaea|Rep: Oxido... 38 0.18
UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy... 38 0.24
UniRef50_Q1GHE2 Cluster: Aldo/keto reductase; n=8; Alphaproteoba... 38 0.24
UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia... 38 0.24
UniRef50_A0K203 Cluster: Aldo/keto reductase; n=2; Arthrobacter|... 38 0.24
UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom... 38 0.24
UniRef50_Q5K825 Cluster: Aryl-alcohol dehydrogenase, putative; n... 38 0.24
UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 38 0.24
UniRef50_Q8YXI8 Cluster: All1225 protein; n=9; Cyanobacteria|Rep... 38 0.32
UniRef50_Q67NQ1 Cluster: Oxidoreductase; n=1; Symbiobacterium th... 38 0.32
UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:... 38 0.32
UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy... 38 0.32
UniRef50_Q034L5 Cluster: Aryl-alcohol dehydrogenase related enzy... 38 0.32
UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative... 38 0.32
UniRef50_Q3I1P2 Cluster: Aldo-keto oxidoreductase; n=6; Bacteria... 37 0.42
UniRef50_Q13GB1 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 37 0.42
UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 37 0.42
UniRef50_A7B2Y7 Cluster: Putative uncharacterized protein; n=1; ... 37 0.42
UniRef50_A5CYR4 Cluster: Predicted oxidoreductases; n=2; Clostri... 37 0.42
UniRef50_P93818 Cluster: F19P19.12 protein; n=4; Arabidopsis tha... 37 0.42
UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere... 37 0.42
UniRef50_Q94A68 Cluster: Uncharacterized oxidoreductase At1g0669... 37 0.42
UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 37 0.56
UniRef50_Q1IYI7 Cluster: Aldo/keto reductase; n=3; Deinococcus g... 37 0.56
UniRef50_A3TNI0 Cluster: Oxidoreductase, aldo/keto reductase fam... 37 0.56
UniRef50_Q016B0 Cluster: COG0667: Predicted oxidoreductases; n=4... 37 0.56
UniRef50_Q23TY7 Cluster: Oxidoreductase, aldo/keto reductase fam... 37 0.56
UniRef50_Q9X0R5 Cluster: Oxidoreductase, aldo/keto reductase fam... 36 0.74
UniRef50_Q2J7H2 Cluster: Aldo/keto reductase; n=16; Bacteria|Rep... 36 0.74
UniRef50_Q7D001 Cluster: AGR_C_2023p; n=14; Proteobacteria|Rep: ... 36 0.74
UniRef50_Q1IXS0 Cluster: Putative aldehyde reductase; n=1; Deino... 36 0.74
UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria... 36 0.74
UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno... 36 0.74
UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ... 36 0.74
UniRef50_Q98G15 Cluster: Mll3531 protein; n=3; Bacteria|Rep: Mll... 36 0.98
UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular organis... 36 0.98
UniRef50_Q7VG62 Cluster: Aldo-keto reductase; n=2; Helicobacter|... 36 0.98
UniRef50_Q2NSC7 Cluster: Putative oxidoreductase; n=1; Sodalis g... 36 0.98
UniRef50_P96923 Cluster: POSSIBLE EXPORTED PROTEIN; n=12; Mycoba... 36 0.98
UniRef50_A6CMV7 Cluster: Putative uncharacterized protein; n=2; ... 36 0.98
UniRef50_A0QHX8 Cluster: General stress protein 69; n=2; Mycobac... 36 0.98
UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa... 36 0.98
UniRef50_Q97UG6 Cluster: Oxidoreductase; n=5; Archaea|Rep: Oxido... 36 0.98
UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 36 0.98
UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 36 1.3
UniRef50_A6LWU9 Cluster: Aldo/keto reductase; n=3; Clostridium|R... 36 1.3
UniRef50_A0YSM3 Cluster: Probable oxidoreductase; n=1; Lyngbya s... 36 1.3
UniRef50_Q011A7 Cluster: Putative aldo/keto reductase family pro... 36 1.3
UniRef50_A1DD54 Cluster: Aldo/keto reductase; n=3; Trichocomacea... 36 1.3
UniRef50_Q5V0P8 Cluster: Oxidoreductase; n=2; Halobacteriaceae|R... 36 1.3
UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 35 1.7
UniRef50_Q28MK3 Cluster: Aldo/keto reductase; n=19; Alphaproteob... 35 1.7
UniRef50_Q1LDA0 Cluster: Aldo/keto reductase; n=1; Ralstonia met... 35 1.7
UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 35 1.7
UniRef50_A7PU13 Cluster: Chromosome chr7 scaffold_31, whole geno... 35 1.7
UniRef50_O59826 Cluster: Potassium channel subunit; n=9; cellula... 35 1.7
UniRef50_Q6XUT6 Cluster: Oxido-reductase/dehydratase; n=3; Bacte... 35 2.3
UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 35 2.3
UniRef50_Q0RGM0 Cluster: Putative aldoketoreductase; n=2; Franki... 35 2.3
UniRef50_A6UAY5 Cluster: Acyltransferase 3; n=1; Sinorhizobium m... 35 2.3
UniRef50_A1B5W4 Cluster: Aldo/keto reductase; n=1; Paracoccus de... 35 2.3
UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 35 2.3
UniRef50_A1CHK2 Cluster: Aldose 1-epimerase, putative; n=11; Pez... 35 2.3
UniRef50_P40690 Cluster: Aldo-keto reductase; n=4; Piroplasmida|... 35 2.3
UniRef50_UPI0000E87D03 Cluster: Aldo/keto reductase; n=1; Methyl... 34 3.0
UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep... 34 3.0
UniRef50_A5UXT4 Cluster: Aldo/keto reductase; n=2; Roseiflexus|R... 34 3.0
UniRef50_A1SCW7 Cluster: Aldo/keto reductase; n=2; Actinomycetal... 34 3.0
UniRef50_A0K0K8 Cluster: Aryl-alcohol dehydrogenase (NADP(+)); n... 34 3.0
UniRef50_Q6TRS1 Cluster: Oxidoreductase; n=1; Ustilago maydis|Re... 34 3.0
UniRef50_Q6CI80 Cluster: Similar to tr|O59826 Schizosaccharomyce... 34 3.0
UniRef50_A5NUR1 Cluster: Aldo/keto reductase precursor; n=2; Alp... 34 3.9
UniRef50_A3I0G0 Cluster: Oxidoreductase; n=1; Algoriphagus sp. P... 34 3.9
UniRef50_Q1JST0 Cluster: Aldo-keto reductase, putative; n=1; Tox... 34 3.9
UniRef50_Q2USD3 Cluster: Voltage-gated shaker-like K+ channel; n... 34 3.9
UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 34 3.9
UniRef50_Q40648 Cluster: Probable voltage-gated potassium channe... 34 3.9
UniRef50_Q38Z15 Cluster: Putative aldo/keto reductase; n=2; Bact... 33 5.2
UniRef50_Q1MEN6 Cluster: Putative oxidoreductase precursor; n=1;... 33 5.2
UniRef50_A3WMV9 Cluster: Sensory box protein/GGDEF domain protei... 33 5.2
UniRef50_A0UUU7 Cluster: Aldo/keto reductase; n=2; Clostridiacea... 33 5.2
UniRef50_Q27ST7 Cluster: Oxidoreductase; n=2; Eukaryota|Rep: Oxi... 33 5.2
UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 33 5.2
UniRef50_UPI00003C85A8 Cluster: hypothetical protein Faci_030001... 33 6.9
UniRef50_Q6MHN8 Cluster: Potassium voltage-gated channel, shaker... 33 6.9
UniRef50_Q3WEJ4 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 33 6.9
UniRef50_Q0LP88 Cluster: Aldo/keto reductase; n=4; Bacteria|Rep:... 33 6.9
UniRef50_Q099T4 Cluster: Oxidoreductase; n=2; Proteobacteria|Rep... 33 6.9
UniRef50_A7B5J6 Cluster: Putative uncharacterized protein; n=1; ... 33 6.9
UniRef50_A5VEK4 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 33 6.9
UniRef50_A1SLH1 Cluster: Aldo/keto reductase; n=27; Bacteria|Rep... 33 6.9
UniRef50_A0JVH3 Cluster: Aldo/keto reductase; n=17; Bacteria|Rep... 33 6.9
UniRef50_Q7Q0Y6 Cluster: ENSANGP00000006086; n=7; Coelomata|Rep:... 33 6.9
UniRef50_Q5ASJ7 Cluster: Putative uncharacterized protein; n=1; ... 33 6.9
UniRef50_Q2NEM6 Cluster: Putative oxidoreductase; n=1; Methanosp... 33 6.9
UniRef50_UPI0000DB7378 Cluster: PREDICTED: similar to Fasciclin-... 33 9.1
UniRef50_Q7NH41 Cluster: Gll2696 protein; n=1; Gloeobacter viola... 33 9.1
UniRef50_Q39MY8 Cluster: Aldo/keto reductase; n=10; Bacteria|Rep... 33 9.1
UniRef50_Q93L10 Cluster: Putative uncharacterized protein; n=1; ... 33 9.1
UniRef50_Q8VV02 Cluster: Putative oxidoreductase; n=1; Streptomy... 33 9.1
UniRef50_Q8GGP2 Cluster: Polyketide synthase; n=1; Streptomyces ... 33 9.1
UniRef50_Q3VZ80 Cluster: Aldo/keto reductase precursor; n=1; Fra... 33 9.1
UniRef50_Q1MJ49 Cluster: Putative general stress protein; n=2; R... 33 9.1
UniRef50_Q04TM6 Cluster: Aryl-alcohol dehydrogenase-related oxid... 33 9.1
UniRef50_A7HER9 Cluster: Aldo/keto reductase; n=2; Anaeromyxobac... 33 9.1
UniRef50_A7AFU4 Cluster: Putative uncharacterized protein; n=1; ... 33 9.1
UniRef50_A0JZE6 Cluster: Aldo/keto reductase; n=1; Arthrobacter ... 33 9.1
UniRef50_Q8ID61 Cluster: Aldo-keto reductase, putative; n=6; Pla... 33 9.1
UniRef50_Q2HAT1 Cluster: Predicted protein; n=1; Chaetomium glob... 33 9.1
UniRef50_A3H9H5 Cluster: Aldo/keto reductase; n=2; Archaea|Rep: ... 33 9.1
UniRef50_Q46851 Cluster: Uncharacterized protein yghZ; n=126; Ba... 33 9.1
UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=... 33 9.1
>UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase
precursor; n=1; Spodoptera littoralis|Rep:
3-dehydroecdysone 3beta-reductase precursor - Spodoptera
littoralis (Egyptian cotton leafworm)
Length = 345
Score = 151 bits (365), Expect = 2e-35
Identities = 63/144 (43%), Positives = 97/144 (67%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
EA++MK++EGV+KRED+F+TTKLWNT H+R +VA A+ ++L K GLDY+DL+LMHWPI L
Sbjct: 86 EAIRMKIDEGVIKREDVFLTTKLWNTHHKREQVAVAMKETLNKTGLDYVDLFLMHWPIAL 145
Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTS 614
N DYSHS+ D++ETWR E+ ++G K+ ++ + + V
Sbjct: 146 NEDYSHSNTDYLETWRATEEMVKLGYTKSIGLSNFNKLQVATVLQECTIKPVALQIEVHP 205
Query: 615 KTFQKEMVEFCQSESVVVMGYSPF 686
+ Q++++ + + E ++VMGYSPF
Sbjct: 206 QIIQEDLITYAKDEGIIVMGYSPF 229
Score = 108 bits (260), Expect = 1e-22
Identities = 48/70 (68%), Positives = 60/70 (85%)
Frame = +1
Query: 49 ASTMEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTAS 228
++T++VP LKM N R MPAI LGTYLGFD+ G V SKDKQLR+VVM+AID+GYRHFDTA+
Sbjct: 17 SATIDVPMLKMLNDREMPAIALGTYLGFDKGGAVTSKDKQLRNVVMQAIDLGYRHFDTAA 76
Query: 229 VYETEQEIGK 258
+Y TE E+G+
Sbjct: 77 IYNTEAEVGE 86
>UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 321
Score = 115 bits (276), Expect = 1e-24
Identities = 59/159 (37%), Positives = 91/159 (57%), Gaps = 11/159 (6%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
+A++ K+++GVVKRED+F+ TK+WN + ++ V A SLKKLGL YIDLYL+HWP
Sbjct: 62 KAIQEKIDQGVVKREDLFVVTKVWNDERKQELVVAACKRSLKKLGLGYIDLYLVHWPFSY 121
Query: 435 NADYSH-----------SDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALS 581
Y + +VD++ETWRG+E+ ++G ++ S + A
Sbjct: 122 PILYQYIVLPTYNAVTLDEVDYIETWRGMEECIKLGLTRSIGVSNFNSQQLTRLLESASI 181
Query: 582 NLMLFK*RVTSKTFQKEMVEFCQSESVVVMGYSPFRFPG 698
++ + + QK++ EFC S+S+ V GYSPF PG
Sbjct: 182 KPVMNQIELHINLNQKKLREFCASKSIAVTGYSPFGAPG 220
Score = 50.8 bits (116), Expect = 3e-05
Identities = 26/66 (39%), Positives = 38/66 (57%)
Frame = +1
Query: 61 EVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240
+V + +++G +P +GLGT+ G + ++ + V AID GYRHFD AS Y
Sbjct: 4 KVDEITLSDGNKVPVLGLGTWQGGND-------PDEVENAVKLAIDAGYRHFDCASFYGN 56
Query: 241 EQEIGK 258
E EIGK
Sbjct: 57 EAEIGK 62
>UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
GA10458-PA - Nasonia vitripennis
Length = 569
Score = 113 bits (271), Expect = 5e-24
Identities = 59/155 (38%), Positives = 86/155 (55%), Gaps = 8/155 (5%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI--- 428
A++ K+++G VKRED+F+TTKL H+ +EV A SL LGLDYIDLYL+HWPI
Sbjct: 319 AIREKIKDGTVKREDLFVTTKLSYYAHKESEVVPACKQSLNDLGLDYIDLYLIHWPIRRY 378
Query: 429 -----GLNADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLML 593
+ SD D++ETW+G+E+ +R G ++ S + A +
Sbjct: 379 FRHNKNASGKLLLSDTDYLETWKGMEECKRQGLARSIGVSNFNSEQITRLLEAAKIKPVN 438
Query: 594 FK*RVTSKTFQKEMVEFCQSESVVVMGYSPFRFPG 698
+ V+ K QK ++EFC+ + V GYSP PG
Sbjct: 439 NQVEVSLKLNQKALIEFCKKHDITVTGYSPLGRPG 473
Score = 112 bits (269), Expect = 9e-24
Identities = 56/158 (35%), Positives = 82/158 (51%), Gaps = 11/158 (6%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437
A++ K+ +G +KREDIF+TTKLW H+ EV A SL+ LG DYIDL+L+HWP
Sbjct: 59 AIREKINDGTIKREDIFVTTKLWCNSHKEDEVVPACKKSLENLGFDYIDLFLVHWPFAFK 118
Query: 438 A-----------DYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSN 584
+ SD D++ETW+G+E+ +R G ++ S A
Sbjct: 119 SGDALTPRDAAGKIEFSDTDYLETWKGMEECKRQGLARSIGLSNFNSEQIARLLSSAKIK 178
Query: 585 LMLFK*RVTSKTFQKEMVEFCQSESVVVMGYSPFRFPG 698
+ + VT QK ++EFC+ + V G+SP PG
Sbjct: 179 PVNNQVEVTMNLNQKPLIEFCKKHEITVTGFSPLGRPG 216
Score = 59.3 bits (137), Expect = 9e-08
Identities = 32/66 (48%), Positives = 41/66 (62%)
Frame = +1
Query: 58 MEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237
M VP++ N+G MP IGLGT+L SK ++ + V AI+VGYRH DTA YE
Sbjct: 1 MPVPTVTFNDGYKMPMIGLGTFL---------SKPGEVAEAVKYAIEVGYRHVDTAFFYE 51
Query: 238 TEQEIG 255
E+EIG
Sbjct: 52 NEKEIG 57
>UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1;
Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase -
Trichoplusia ni (Cabbage looper)
Length = 308
Score = 100 bits (240), Expect = 3e-20
Identities = 49/140 (35%), Positives = 81/140 (57%)
Frame = +3
Query: 273 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH 452
+++G+VKRE++F+TTKLWN +H R +V A+ +SL KLGL Y+DLYL+H P N +
Sbjct: 86 IQQGLVKREELFVTTKLWNDKHGRHQVVPALRESLTKLGLSYVDLYLIHSPEATNENGDP 145
Query: 453 SDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTSKTFQKE 632
D+D + TW G+E+A+++G K+ ++ + + + + V Q++
Sbjct: 146 VDIDVLNTWNGMEEAKKLGLAKSIGVSNFDTALLDRLIAGSNTVPAVNQIEVHPSKTQEK 205
Query: 633 MVEFCQSESVVVMGYSPFRF 692
+V + VM YSPF F
Sbjct: 206 LVADSHERGIEVMAYSPFGF 225
Score = 50.0 bits (114), Expect = 6e-05
Identities = 26/66 (39%), Positives = 42/66 (63%)
Frame = +1
Query: 61 EVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240
+ P ++N+G +P++ LGT+ GF G + ++R V+ AI GYRH DTA++Y
Sbjct: 23 KAPLKQLNDGNAIPSLALGTF-GF---GDIP----KVRQAVLWAIQAGYRHIDTAALYGN 74
Query: 241 EQEIGK 258
E+E+GK
Sbjct: 75 EEEVGK 80
>UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 316
Score = 97.9 bits (233), Expect = 2e-19
Identities = 56/159 (35%), Positives = 84/159 (52%), Gaps = 11/159 (6%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW---- 422
EA+K ++EG VKRE++FIT+K+WNT H + + I+ L L L Y+DL L+HW
Sbjct: 57 EALKEILDEGKVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHWPQGY 116
Query: 423 -------PIGLNADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALS 581
P G N +SDVD++ETW+ E AQ+ G ++ T S + A
Sbjct: 117 AEGAELFPAGENGKMRYSDVDYLETWKAFEAAQKAGKCRSIGLSNFTHSQIQRVWDAAEV 176
Query: 582 NLMLFK*RVTSKTFQKEMVEFCQSESVVVMGYSPFRFPG 698
+ + Q ++ EFC+ + +VV+GYSP PG
Sbjct: 177 KPACLQVELHPYFTQVKLREFCKEKGIVVVGYSPLGNPG 215
Score = 51.6 bits (118), Expect = 2e-05
Identities = 26/65 (40%), Positives = 40/65 (61%)
Frame = +1
Query: 64 VPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243
V SLK+N+G +PAIGLGT+ +SK ++ + A+ GYRH D A VY+ +
Sbjct: 2 VQSLKLNSGYSIPAIGLGTW---------QSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQ 52
Query: 244 QEIGK 258
+E+G+
Sbjct: 53 KEVGE 57
>UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 333
Score = 97.5 bits (232), Expect = 3e-19
Identities = 57/147 (38%), Positives = 78/147 (53%), Gaps = 15/147 (10%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL----------- 434
+KRED+FITTK+WNT H + +VA+ N SL L LDYIDLY+MHWP+G
Sbjct: 68 LKREDVFITTKVWNTFHAKEDVAECFNRSLTDLQLDYIDLYIMHWPLGFQNLGPTVMFPR 127
Query: 435 --NADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RV 608
D +SDV ++ETW +ED + G K+ S + + + +V
Sbjct: 128 TETGDIVYSDVHYLETWSAMEDLVKTGKCKSLGLSNFNSKQLDDVLQHSTVPPSVL--QV 185
Query: 609 TSKTF--QKEMVEFCQSESVVVMGYSP 683
S F Q E++ FC+ SVVV YSP
Sbjct: 186 ESHPFLPQVELLNFCRERSVVVSAYSP 212
Score = 46.4 bits (105), Expect = 7e-04
Identities = 23/62 (37%), Positives = 35/62 (56%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249
S+ + +G MP +GLGT+ K K ++ + A+D GYRHFD A +Y E+E
Sbjct: 4 SVTLPSGHAMPLVGLGTW---------KLKADEVAGAIGAAVDAGYRHFDCALIYGNEKE 54
Query: 250 IG 255
+G
Sbjct: 55 VG 56
>UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate
division TM7 genomosp. GTL1|Rep: Aldehyde reductase -
candidate division TM7 genomosp. GTL1
Length = 299
Score = 96.7 bits (230), Expect = 5e-19
Identities = 51/155 (32%), Positives = 81/155 (52%), Gaps = 11/155 (7%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI-- 428
E ++ +++GVVKRED+F+T+KLWNT H + +V A +L LGLDY+DLYL+HW +
Sbjct: 56 EGIRRTIDQGVVKREDLFVTSKLWNTDHAQVDVGVACRKTLNDLGLDYLDLYLIHWGVAF 115
Query: 429 --GLNADYSHSD-------VDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALS 581
G N + D + ETW+ +E+ G +K+ T+ A
Sbjct: 116 EHGDNLEPLDDDGVAKFSFISMKETWQAMEELVEQGLVKSMGVANFTAPMLLDLLSYAKI 175
Query: 582 NLMLFK*RVTSKTFQKEMVEFCQSESVVVMGYSPF 686
+ + + Q ++V FC S+++ V YSPF
Sbjct: 176 KPAVHQIELHPYLAQNDLVAFCYSQNIAVTAYSPF 210
Score = 36.3 bits (80), Expect = 0.74
Identities = 20/62 (32%), Positives = 31/62 (50%)
Frame = +1
Query: 73 LKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252
L + N + +P +G GT+ + D+V AI GYRH D A +Y E+E+
Sbjct: 4 LTLRNKQTLPLLGYGTW---------ELPTGTTADLVETAIKAGYRHIDCAMIYGNEKEV 54
Query: 253 GK 258
G+
Sbjct: 55 GE 56
>UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep:
Aldo-keto reductase - Aedes aegypti (Yellowfever
mosquito)
Length = 324
Score = 95.1 bits (226), Expect = 2e-18
Identities = 57/165 (34%), Positives = 83/165 (50%), Gaps = 19/165 (11%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL- 434
A++ K+EEGVV RE++F+TTKLWNT H V A SL+ LGLDY+DL+L+H P G
Sbjct: 62 AIRAKIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSLEHLGLDYVDLFLIHMPFGYE 121
Query: 435 --------------NADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWR----G 560
N + SD D+++TW+ +E G + + S
Sbjct: 122 FNGWDPEKRTPLDDNGNVLCSDDDYVDTWKAMEKLLESGRVHSIGVSNFNSEQLERILAN 181
Query: 561 C*KKALSNLMLFK*RVTSKTFQKEMVEFCQSESVVVMGYSPFRFP 695
C K ++N + R+ QK ++EFC +VV +SPF P
Sbjct: 182 CRVKPVTNQVECSARIN----QKLLIEFCMERDIVVTAHSPFGRP 222
Score = 54.4 bits (125), Expect = 3e-06
Identities = 29/65 (44%), Positives = 38/65 (58%)
Frame = +1
Query: 64 VPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243
+P++K+NNG MPAIGLGT + SK + VM AID G+RH DTA Y E
Sbjct: 6 IPTVKLNNGLEMPAIGLGTSM---------SKGDECCKAVMTAIDEGFRHIDTAYNYRNE 56
Query: 244 QEIGK 258
+G+
Sbjct: 57 DVVGR 61
Score = 38.3 bits (85), Expect = 0.18
Identities = 17/34 (50%), Positives = 23/34 (67%)
Frame = +2
Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIE 604
+G V IG+SNFN +QLER+L +KP Q+E
Sbjct: 159 SGRVHSIGVSNFNSEQLERILANCRVKPVTNQVE 192
>UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:
Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 93.1 bits (221), Expect = 6e-18
Identities = 45/160 (28%), Positives = 86/160 (53%), Gaps = 11/160 (6%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL- 434
A++ K+++G+++R+D+FI +KLW T H ++ N SL L LDY+D YL+H+P+GL
Sbjct: 32 AIQNKIQQGIIRRQDMFIVSKLWGTHHAPEDIPVCFNKSLSDLQLDYLDQYLVHFPVGLK 91
Query: 435 ----------NADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSN 584
+ +D+D+++ WRG+E + G +K+ T A
Sbjct: 92 KVGDELFPERDGKILTTDIDYVDVWRGMEALKATGKVKSIGVSNFTMEQIDRLLSVAKIP 151
Query: 585 LMLFK*RVTSKTFQKEMVEFCQSESVVVMGYSPFRFPGXP 704
+ + + Q +++++C+S+++ + +SPF PG P
Sbjct: 152 PAVNQVELHPYLVQSDLIDYCKSKNIALTAHSPFGSPGRP 191
>UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5;
Bacteroidetes|Rep: Aldehyde reductase - Croceibacter
atlanticus HTCC2559
Length = 316
Score = 89.4 bits (212), Expect = 7e-17
Identities = 49/154 (31%), Positives = 76/154 (49%), Gaps = 11/154 (7%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
EA K E G VKREDIF+T+KLWN H++ +V A+ +LK L LDY+DLYLMHWP+
Sbjct: 56 EAFKESFESGNVKREDIFVTSKLWNNAHKKEDVIPALKKTLKDLNLDYLDLYLMHWPVAF 115
Query: 435 NAD---YSHSDVDFM--------ETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALS 581
+ D D++ ET + +A++ G +K + K
Sbjct: 116 KPSVNGFPEKDEDYLSLEEAPLHETLNAMIEAKKQGLIKHVGVSNFSKEKLESLKGKVEE 175
Query: 582 NLMLFK*RVTSKTFQKEMVEFCQSESVVVMGYSP 683
+ + + Q ++ +C E +++ GYSP
Sbjct: 176 MPEMNQVELHPYLPQNDLYSYCSKEGILLTGYSP 209
Score = 41.9 bits (94), Expect = 0.015
Identities = 21/63 (33%), Positives = 36/63 (57%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249
+LK +G +P+IGLGT+ KS + ++ V A++ GY+H D A+ Y+ E
Sbjct: 3 TLKFRDGDSIPSIGLGTW---------KSDPEDVKKAVKIALENGYKHIDCAAAYDNEDA 53
Query: 250 IGK 258
+G+
Sbjct: 54 VGE 56
>UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9;
Endopterygota|Rep: ENSANGP00000031808 - Anopheles
gambiae str. PEST
Length = 316
Score = 89.0 bits (211), Expect = 1e-16
Identities = 52/162 (32%), Positives = 78/162 (48%), Gaps = 12/162 (7%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG- 431
E + K+ EGVVKRED+F+T+KLWNT HR V A +L+ L LDY+DLYL+HWP+G
Sbjct: 61 EGIAAKIAEGVVKREDLFVTSKLWNTFHRPDLVEGACKTTLQNLKLDYLDLYLIHWPVGY 120
Query: 432 --------LNAD---YSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKAL 578
+ D + SD D+++TW +E G ++ + + A
Sbjct: 121 QEGTELFPMGPDGKTFLFSDADYVDTWPEMEKLVDAGLVRNIGVSNFNAKQVQRVLDVAR 180
Query: 579 SNLMLFK*RVTSKTFQKEMVEFCQSESVVVMGYSPFRFPGXP 704
+ Q ++ FC + ++V YSP P P
Sbjct: 181 IPPATNQIECHPYLHQSKITTFCAEKGIIVTAYSPLGSPARP 222
Score = 49.6 bits (113), Expect = 7e-05
Identities = 27/65 (41%), Positives = 34/65 (52%)
Frame = +1
Query: 64 VPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243
VP+ NG +P GLGT+ S Q+ V AIDVGYRH D A VY+ E
Sbjct: 6 VPNAIFKNGNSIPMFGLGTW---------NSPPGQVAQAVKDAIDVGYRHIDCAHVYQNE 56
Query: 244 QEIGK 258
E+G+
Sbjct: 57 HEVGE 61
Score = 39.5 bits (88), Expect = 0.079
Identities = 18/35 (51%), Positives = 24/35 (68%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
G+V+ IG+SNFN +Q++RVL I P QIE H
Sbjct: 157 GLVRNIGVSNFNAKQVQRVLDVARIPPATNQIECH 191
>UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like
protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase
family 1 member C-like protein 2 - Homo sapiens (Human)
Length = 320
Score = 76.2 bits (179), Expect(2) = 1e-16
Identities = 31/57 (54%), Positives = 44/57 (77%)
Frame = +3
Query: 261 VKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431
++ K++EG V+RED+FI TKLW T H+++ V A SLK L L+Y+DLYL+HWP+G
Sbjct: 50 IRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
Score = 39.9 bits (89), Expect = 0.060
Identities = 20/53 (37%), Positives = 30/53 (56%)
Frame = +1
Query: 97 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
+PA+GL ++ K+ ++ + V AID GYRHFD A Y E+E+G
Sbjct: 4 IPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVG 47
Score = 38.7 bits (86), Expect = 0.14
Identities = 22/37 (59%), Positives = 26/37 (70%), Gaps = 2/37 (5%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEGH 610
G+VK IG+SNFN +QLER+L K G KP QIE H
Sbjct: 162 GLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECH 198
Score = 33.1 bits (72), Expect(2) = 1e-16
Identities = 21/79 (26%), Positives = 30/79 (37%), Gaps = 2/79 (2%)
Frame = +3
Query: 453 SDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTSKTF--Q 626
SD DF++TW +ED G +K K ++ + Q
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQ 203
Query: 627 KEMVEFCQSESVVVMGYSP 683
K ++ FCQS V V Y P
Sbjct: 204 KNLISFCQSRDVSVTAYRP 222
>UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep:
GCY protein - Lodderomyces elongisporus (Yeast)
(Saccharomyces elongisporus)
Length = 295
Score = 87.8 bits (208), Expect = 2e-16
Identities = 38/87 (43%), Positives = 60/87 (68%), Gaps = 2/87 (2%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
+ V + + V R++IF+TTKLWN QH+ E A+++SLKKLGL+Y+DLYL+HWP+ +
Sbjct: 61 DQVGRAIADSGVSRDEIFVTTKLWNDQHKDPE--GALDESLKKLGLEYVDLYLIHWPLSV 118
Query: 435 N--ADYSHSDVDFMETWRGLEDAQRMG 509
+ + + D DF++TWR L+ + G
Sbjct: 119 DPKTEKPYDDYDFVDTWRNLQKIYKEG 145
Score = 47.2 bits (107), Expect = 4e-04
Identities = 22/60 (36%), Positives = 36/60 (60%)
Frame = +1
Query: 79 MNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
+NNG +PAIGLGT+L +++ K+ + A+ GY+H DTA+ Y E ++G+
Sbjct: 14 LNNGLKIPAIGLGTWLADEEDAAYKA--------TLTALKNGYKHIDTAAAYGNEDQVGR 65
Score = 33.9 bits (74), Expect = 3.9
Identities = 18/35 (51%), Positives = 25/35 (71%), Gaps = 2/35 (5%)
Frame = +2
Query: 512 VKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEGH 610
VK IG+SNFNK++L+++L EG + P QIE H
Sbjct: 148 VKAIGVSNFNKKKLDKLLNSEGVNVVPVINQIEAH 182
>UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13;
n=11; Theria|Rep: Aldo-keto reductase family 1 member
C13 - Mus musculus (Mouse)
Length = 323
Score = 86.6 bits (205), Expect = 5e-16
Identities = 51/154 (33%), Positives = 85/154 (55%), Gaps = 13/154 (8%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
+A++ K++ GVVKRED+FITTKLW T R V A+ SLKKL LDY+DLY+MH+P+ +
Sbjct: 63 QAIQSKIKAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPM 122
Query: 435 NA---DYSHSD--------VDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALS 581
+ D+ ++ VDF +TW LE+ + G +K+ K
Sbjct: 123 KSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPGL 182
Query: 582 NLMLFK*RVTSKTF--QKEMVEFCQSESVVVMGY 677
+V + Q++++++C+S+ +V++ Y
Sbjct: 183 KYKPVCNQVECHLYLNQRKLLDYCESKDIVLVAY 216
Score = 53.6 bits (123), Expect = 5e-06
Identities = 28/62 (45%), Positives = 38/62 (61%)
Frame = +1
Query: 73 LKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252
+K+N+G +PA+G GTY V KSK + A+DVGYRH DTA Y+ E+EI
Sbjct: 8 VKLNDGHLIPALGFGTY---KPKEVPKSKSLE---AACLALDVGYRHVDTAYAYQVEEEI 61
Query: 253 GK 258
G+
Sbjct: 62 GQ 63
Score = 44.4 bits (100), Expect = 0.003
Identities = 24/46 (52%), Positives = 30/46 (65%), Gaps = 2/46 (4%)
Frame = +2
Query: 482 RIGRCSANGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEGHL 613
R+ C G+VK IG+SNFN +QLER+L K G KP Q+E HL
Sbjct: 150 RLEECKDAGLVKSIGVSNFNHRQLERILNKPGLKYKPVCNQVECHL 195
>UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep:
GA19341-PA - Drosophila pseudoobscura (Fruit fly)
Length = 315
Score = 85.8 bits (203), Expect = 9e-16
Identities = 46/153 (30%), Positives = 76/153 (49%), Gaps = 12/153 (7%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437
A++ K++EG+V R+++FIT+KLWNT H+ V A SL+ LG+DY+DLYLMHWP+
Sbjct: 59 AIREKIQEGLVTRDELFITSKLWNTFHKPELVRAACETSLRNLGIDYLDLYLMHWPMAYK 118
Query: 438 ADYS------------HSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALS 581
+ + D+D+++TW+ +ED G + A A
Sbjct: 119 SGDNLYPTCPDTGKAVFEDIDYLDTWKAMEDLVDSGLVNAIGVSNFNEKQINRLLCLAKL 178
Query: 582 NLMLFK*RVTSKTFQKEMVEFCQSESVVVMGYS 680
++ + QK ++ C ++ V YS
Sbjct: 179 KPVMLQIECHPYLRQKSLITLCYDNAIGVTAYS 211
Score = 52.0 bits (119), Expect = 1e-05
Identities = 26/66 (39%), Positives = 37/66 (56%)
Frame = +1
Query: 58 MEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237
M PS +++GR MP +GLGT+ +S + + V AID+GYRHFD A +Y
Sbjct: 1 MSTPSFLLSSGRNMPMVGLGTW---------RSPPEVVAQAVKDAIDIGYRHFDCAHIYG 51
Query: 238 TEQEIG 255
E +G
Sbjct: 52 NELHVG 57
>UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep:
Aldose reductase - Mus musculus (Mouse)
Length = 316
Score = 85.0 bits (201), Expect = 2e-15
Identities = 53/162 (32%), Positives = 79/162 (48%), Gaps = 13/162 (8%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL- 434
A++ K++E VVKR+D+FI +KLW T H ++ V A +L L LDY+DLYL+HWP G
Sbjct: 58 ALQEKLKEQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFK 117
Query: 435 -NADY---------SHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSN 584
DY SD DF++TW +E G +K K
Sbjct: 118 PGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLK 177
Query: 585 LMLFK*RVTSKTF--QKEMVEFCQSESVVVMGYSPFRFPGXP 704
++ + Q++++E+C S+ +VV YSP P P
Sbjct: 178 YKPAVNQIECHPYLTQEKLIEYCHSKGIVVTAYSPLGSPDRP 219
Score = 55.6 bits (128), Expect = 1e-06
Identities = 28/61 (45%), Positives = 38/61 (62%)
Frame = +1
Query: 73 LKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252
L++NNG MP +GLGT+ KS Q+ + V AID+GYRH D A VY+ E+E+
Sbjct: 5 LELNNGTKMPTLGLGTW---------KSPPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEV 55
Query: 253 G 255
G
Sbjct: 56 G 56
Score = 36.7 bits (81), Expect = 0.56
Identities = 21/37 (56%), Positives = 25/37 (67%), Gaps = 2/37 (5%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEGH 610
G+VK IG+SNFN Q+ER+L K G KP QIE H
Sbjct: 152 GLVKTIGVSNFNPLQIERILNKPGLKYKPAVNQIECH 188
>UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32;
Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 315
Score = 84.6 bits (200), Expect = 2e-15
Identities = 51/153 (33%), Positives = 79/153 (51%), Gaps = 7/153 (4%)
Frame = +3
Query: 261 VKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP----- 425
+K E+ VVKRED+FIT+KLW T H +V +A+N +LK L L+Y+DLYL+HWP
Sbjct: 62 LKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKK 121
Query: 426 --IGLNADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK 599
+G+ + + VD TW+ +E G +A ++ + A + +
Sbjct: 122 GSVGIKPE-NLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQ 180
Query: 600 *RVTSKTFQKEMVEFCQSESVVVMGYSPFRFPG 698
Q ++ EFC+S+ V + YSP PG
Sbjct: 181 VECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPG 213
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/60 (40%), Positives = 33/60 (55%)
Frame = +1
Query: 76 KMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
K+N G P++GLGT+ G+V D V A+ +GYRH D A +Y E+EIG
Sbjct: 9 KLNTGAKFPSVGLGTWQA--SPGLVG-------DAVAAAVKIGYRHIDCAQIYGNEKEIG 59
>UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae
str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae
str. PEST
Length = 319
Score = 83.8 bits (198), Expect = 4e-15
Identities = 52/163 (31%), Positives = 82/163 (50%), Gaps = 16/163 (9%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
+A++ K+ EGV++RED+F+TTKLWNT H V +A S L + YIDL+LMH P+G+
Sbjct: 60 QAIRDKIAEGVIRREDVFVTTKLWNTFHDPQHVEEAFRRSFDMLDIGYIDLFLMHSPMGV 119
Query: 435 N-ADYSH--------------SDVDFMETWRGLEDAQRMG*LKASDCLTS-TSSSWRGC* 566
+ Y + SDVD++ETW+ +E G S L++ S
Sbjct: 120 QFSGYEYADMQPKDAAGNMLFSDVDYVETWKAMEKLVTAGGRVRSIGLSNFNSEQIERIL 179
Query: 567 KKALSNLMLFK*RVTSKTFQKEMVEFCQSESVVVMGYSPFRFP 695
+ A + + Q++++ FCQ+ + V Y P P
Sbjct: 180 QIATVKPVNNQVEANPGYDQRKLIAFCQARGITVTAYGPMGRP 222
Score = 58.0 bits (134), Expect = 2e-07
Identities = 30/66 (45%), Positives = 43/66 (65%)
Frame = +1
Query: 61 EVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240
+VP+++ +NG +P +G GTYL Q G Q ++V +AID+GYRH DTA +YE
Sbjct: 4 QVPTVRFSNGYEIPVLGYGTYLA--QKG-------QCVELVKKAIDLGYRHIDTAFLYEN 54
Query: 241 EQEIGK 258
E EIG+
Sbjct: 55 EVEIGQ 60
Score = 44.4 bits (100), Expect = 0.003
Identities = 19/38 (50%), Positives = 28/38 (73%)
Frame = +2
Query: 497 SANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
+A G V+ IGLSNFN +Q+ER+L+ T+KP Q+E +
Sbjct: 157 TAGGRVRSIGLSNFNSEQIERILQIATVKPVNNQVEAN 194
>UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep:
Protein GCY - Saccharomyces cerevisiae (Baker's yeast)
Length = 312
Score = 83.4 bits (197), Expect = 5e-15
Identities = 54/164 (32%), Positives = 85/164 (51%), Gaps = 21/164 (12%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
+ V +++ V RE+IF+TTKLW TQH EVA ++ SLK+LGLDY+DLYLMHWP L
Sbjct: 60 DQVGQAIKDSGVPREEIFVTTKLWCTQHHEPEVA--LDQSLKRLGLDYVDLYLMHWPARL 117
Query: 435 NADY-SHSDV------------------DFMETWRGLEDAQRMG*LKASDCLTSTSSSWR 557
+ Y + D+ +F++TW +++ + G KA + ++ +
Sbjct: 118 DPAYIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLK 177
Query: 558 GC*KKALSNLMLFK*RVTSKTF--QKEMVEFCQSESVVVMGYSP 683
+ L +V Q E++ FC+S+ +VV YSP
Sbjct: 178 DLLASQGNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAYSP 221
Score = 47.2 bits (107), Expect = 4e-04
Identities = 23/62 (37%), Positives = 35/62 (56%)
Frame = +1
Query: 73 LKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252
L +N G +P IGLGT+ +SK+ V+ A+ GYRH DTA++Y E ++
Sbjct: 12 LSLNTGAQIPQIGLGTW---------QSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQV 62
Query: 253 GK 258
G+
Sbjct: 63 GQ 64
>UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep:
Aldose reductase - Homo sapiens (Human)
Length = 316
Score = 82.6 bits (195), Expect = 9e-15
Identities = 50/162 (30%), Positives = 79/162 (48%), Gaps = 13/162 (8%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL- 434
A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+DLYL+HWP G
Sbjct: 58 AIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFK 117
Query: 435 ----------NADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSN 584
+ + SD + ++TW +E+ G +KA K
Sbjct: 118 PGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLK 177
Query: 585 LMLFK*RVTSKTF--QKEMVEFCQSESVVVMGYSPFRFPGXP 704
++ + Q++++++CQS+ +VV YSP P P
Sbjct: 178 YKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP 219
Score = 54.4 bits (125), Expect = 3e-06
Identities = 29/61 (47%), Positives = 36/61 (59%)
Frame = +1
Query: 73 LKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252
L +NNG MP +GLGT+ KS Q+ + V AIDVGYRH D A VY+ E E+
Sbjct: 5 LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 253 G 255
G
Sbjct: 56 G 56
Score = 35.1 bits (77), Expect = 1.7
Identities = 20/37 (54%), Positives = 24/37 (64%), Gaps = 2/37 (5%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEGH 610
G+VK IG+SNFN Q+E +L K G KP QIE H
Sbjct: 152 GLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECH 188
>UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4;
Catarrhini|Rep: Isoform 2 of Q96JD6 - Homo sapiens
(Human)
Length = 263
Score = 76.2 bits (179), Expect(2) = 1e-14
Identities = 31/57 (54%), Positives = 44/57 (77%)
Frame = +3
Query: 261 VKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431
++ K++EG V+RED+FI TKLW T H+++ V A SLK L L+Y+DLYL+HWP+G
Sbjct: 50 IRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
Score = 39.9 bits (89), Expect = 0.060
Identities = 20/53 (37%), Positives = 30/53 (56%)
Frame = +1
Query: 97 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
+PA+GL ++ K+ ++ + V AID GYRHFD A Y E+E+G
Sbjct: 4 IPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVG 47
Score = 34.7 bits (76), Expect = 2.3
Identities = 14/22 (63%), Positives = 19/22 (86%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKE 571
G+VK IG+SNFN +QLER+L +
Sbjct: 162 GLVKNIGVSNFNHEQLERLLNK 183
Score = 26.6 bits (56), Expect(2) = 1e-14
Identities = 10/22 (45%), Positives = 14/22 (63%)
Frame = +3
Query: 453 SDVDFMETWRGLEDAQRMG*LK 518
SD DF++TW +ED G +K
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVK 165
>UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose
reductase; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to aldose reductase -
Strongylocentrotus purpuratus
Length = 274
Score = 82.2 bits (194), Expect = 1e-14
Identities = 49/148 (33%), Positives = 73/148 (49%)
Frame = +3
Query: 261 VKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA 440
+K K + VVKREDIFIT+KLWN +H +V QA + +LK L L Y+DLYLMHWP+
Sbjct: 43 LKEKFDANVVKREDIFITSKLWNNKHHPDDVEQACDITLKNLQLSYVDLYLMHWPM---- 98
Query: 441 DYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTSKT 620
++ +E G KA + + +KA + +
Sbjct: 99 -----------AYQAMEKLVTSGKCKAIGLSNFSMKMMKRVIEKATIQPANLQVELHPLL 147
Query: 621 FQKEMVEFCQSESVVVMGYSPFRFPGXP 704
Q++++EFC+ ++ V YSP P P
Sbjct: 148 TQEKLIEFCKEHNMTVTAYSPLGAPDRP 175
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/36 (44%), Positives = 27/36 (75%)
Frame = +2
Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
+G K IGLSNF+ + ++RV+++ TI+P +Q+E H
Sbjct: 109 SGKCKAIGLSNFSMKMMKRVIEKATIQPANLQVELH 144
Score = 38.7 bits (86), Expect = 0.14
Identities = 18/34 (52%), Positives = 20/34 (58%)
Frame = +1
Query: 154 SKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
SK Q+ V AID GYRH D A VY E E+G
Sbjct: 7 SKPGQVEAAVKAAIDCGYRHIDCAHVYGNEAEVG 40
>UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18;
n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member
C18 - Mus musculus (Mouse)
Length = 323
Score = 82.2 bits (194), Expect = 1e-14
Identities = 40/100 (40%), Positives = 60/100 (60%), Gaps = 11/100 (11%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
+A+ K+E+G VKREDIF T+KLW+T HR V ++ +SL+KL LDY+DLYL+H+P+ L
Sbjct: 63 QAILSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSL 122
Query: 435 -----------NADYSHSDVDFMETWRGLEDAQRMG*LKA 521
+ + VD +TW +E + G K+
Sbjct: 123 KPGNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKS 162
Score = 44.8 bits (101), Expect = 0.002
Identities = 21/66 (31%), Positives = 39/66 (59%)
Frame = +1
Query: 61 EVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240
++ +++N+G +P +G GTY + +K K + + AIDVG+ H D + +Y+
Sbjct: 4 KIQKIELNDGHSIPVLGFGTYATEEH---LKKKSMESTKI---AIDVGFCHIDCSHLYQN 57
Query: 241 EQEIGK 258
E+EIG+
Sbjct: 58 EEEIGQ 63
Score = 40.3 bits (90), Expect = 0.045
Identities = 21/43 (48%), Positives = 28/43 (65%), Gaps = 2/43 (4%)
Frame = +2
Query: 491 RCSANGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEGHL 613
+C G+ K IG+SNFN++QLE +L K G KP Q+E HL
Sbjct: 153 KCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHL 195
>UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone
synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent
6'-deoxychalcone synthase - Glycine max (Soybean)
Length = 315
Score = 82.2 bits (194), Expect = 1e-14
Identities = 46/153 (30%), Positives = 78/153 (50%), Gaps = 8/153 (5%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG- 431
EA+K + G+V R+D+F+T+KLW T++ V A+ SLK L L+Y+DLYL+HWP+
Sbjct: 67 EALKEAIHLGLVSRQDLFVTSKLWVTENHPHLVLPALRKSLKTLQLEYLDLYLIHWPLSS 126
Query: 432 ----LNADYSHSDV---DFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLM 590
+ D+ D W +E+ Q++G KA + + A +
Sbjct: 127 QPGKFSFPIEVEDLLPFDVKGVWESMEECQKLGLTKAIGVSNFSVKKLQNLLSVATIRPV 186
Query: 591 LFK*RVTSKTFQKEMVEFCQSESVVVMGYSPFR 689
+ + + QK++ EFC+ ++V +SP R
Sbjct: 187 VDQVEMNLAWQQKKLREFCKENGIIVTAFSPLR 219
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/73 (31%), Positives = 42/73 (57%), Gaps = 3/73 (4%)
Frame = +1
Query: 49 ASTMEVPSLKMNNG---RXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFD 219
A+ +E+P++ N + MP +G+G+ F + K ++ ++ A+ GYRHFD
Sbjct: 2 AAAIEIPTIVFPNSSAQQRMPVVGMGSAPDF-------TCKKDTKEAIIEAVKQGYRHFD 54
Query: 220 TASVYETEQEIGK 258
TA+ Y +EQ +G+
Sbjct: 55 TAAAYGSEQALGE 67
>UniRef50_Q41399 Cluster: Chalcone reductase; n=4;
eudicotyledons|Rep: Chalcone reductase - Sesbania
rostrata
Length = 322
Score = 81.8 bits (193), Expect = 2e-14
Identities = 46/152 (30%), Positives = 79/152 (51%), Gaps = 10/152 (6%)
Frame = +3
Query: 258 AVKMKVEEGVVK-REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
AV +E+G++K R+++FIT+K WNT + A+ +LKKLG++Y+DLYL+HWP+ L
Sbjct: 65 AVSKAIEQGLIKSRDEVFITSKPWNTDAHHDLIVPALKTTLKKLGMEYVDLYLIHWPVRL 124
Query: 435 NAD------YSHSDV---DFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNL 587
D +S D+ D TW+ +E+ R+G K+ + + A
Sbjct: 125 RHDLENPVIFSKEDLLPFDIEGTWKAMEECYRLGLAKSIGICNYGTKKLTKLLEIATIPP 184
Query: 588 MLFK*RVTSKTFQKEMVEFCQSESVVVMGYSP 683
+ + + Q + EFC+ + + V +SP
Sbjct: 185 AVNQVEMNPSWQQGNLREFCKQKGIHVSAWSP 216
Score = 54.4 bits (125), Expect = 3e-06
Identities = 28/65 (43%), Positives = 40/65 (61%)
Frame = +1
Query: 61 EVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240
++P + +N+G MP IG+GT + + V L + + AI VGYRHFD+ASVY T
Sbjct: 5 KIPEVLLNSGHKMPVIGMGTSVESRPSNDV------LASIFVDAIQVGYRHFDSASVYGT 58
Query: 241 EQEIG 255
E+ IG
Sbjct: 59 EEAIG 63
>UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep:
Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 81.4 bits (192), Expect = 2e-14
Identities = 51/145 (35%), Positives = 73/145 (50%), Gaps = 2/145 (1%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
EA+ V E V+RE++++TTKLW + QA DS +LG+DY+DLYLMHWP +
Sbjct: 64 EALGKAVTESGVQREELWVTTKLWPGDYGYQSTKQACRDSRARLGVDYLDLYLMHWPDSM 123
Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTS 614
S +V +ETWR LE+ G +A K ++ +V
Sbjct: 124 VPGRSSQEVR-LETWRALEELYDEGLCRAIGVSNFLIPHLNEL--KDSGGIVPHVNQVEF 180
Query: 615 KTFQKEM--VEFCQSESVVVMGYSP 683
FQ+ M VE C+ E++V GY P
Sbjct: 181 HPFQQPMKLVEHCRKENIVFEGYCP 205
Score = 34.7 bits (76), Expect = 2.3
Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
Frame = +1
Query: 52 STMEVPSLKMNNGRXMPAIGLGT--YLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTA 225
+ + P++ ++NG +P +GLGT Y G+ V+ + + G RH DTA
Sbjct: 9 TALSCPAVPLHNGLNIPILGLGTSHYGGYSHEAVLYALQ-----------ECGIRHIDTA 57
Query: 226 SVYETEQEIGK 258
Y E+ +GK
Sbjct: 58 KRYGCEEALGK 68
>UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep:
Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea)
Length = 321
Score = 81.4 bits (192), Expect = 2e-14
Identities = 46/151 (30%), Positives = 79/151 (52%), Gaps = 9/151 (5%)
Frame = +3
Query: 255 EAVKMKVEEGVVK-REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431
+A+ + EG++K R+++FIT+KLW + R V A+ +LK L L+YID+YL+HWP+
Sbjct: 64 DAIAEALGEGLIKSRDELFITSKLWCSDAHRENVEPALQKTLKNLKLEYIDMYLIHWPVS 123
Query: 432 L---NADYSHSDVDFME-----TWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNL 587
N +Y DF++ W +E+ Q++G KA + A
Sbjct: 124 SKPGNYEYPIKKEDFLQMDYKSVWEAMEECQKLGLTKAIGVSNFSCKKLSDVLANAKVPP 183
Query: 588 MLFK*RVTSKTFQKEMVEFCQSESVVVMGYS 680
+ + V QK++ EFC+S ++V+ Y+
Sbjct: 184 AVNQVEVNPCWQQKQLTEFCKSNGILVVAYA 214
Score = 46.0 bits (104), Expect = 0.001
Identities = 24/65 (36%), Positives = 39/65 (60%), Gaps = 1/65 (1%)
Frame = +1
Query: 64 VPSLKMNNG-RXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240
+P + +++G R MP +GLGT + + +R V A+ +GYRHFDTA++Y +
Sbjct: 5 IPEVPLSSGGRKMPVLGLGTAADPPVD------PETVRKAVTEALKLGYRHFDTAALYNS 58
Query: 241 EQEIG 255
EQ +G
Sbjct: 59 EQPLG 63
>UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA -
Drosophila melanogaster (Fruit fly)
Length = 322
Score = 81.4 bits (192), Expect = 2e-14
Identities = 44/154 (28%), Positives = 75/154 (48%), Gaps = 13/154 (8%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437
A++ K++EGVV R+++FIT+KLWNT H+ V A S++ LG+ Y++LYLMHWP+
Sbjct: 59 ALREKMDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYK 118
Query: 438 ADYSH-------------SDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKAL 578
+ + D+D+++TWR +E+ G +A A
Sbjct: 119 SGSDNLYPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSVAK 178
Query: 579 SNLMLFK*RVTSKTFQKEMVEFCQSESVVVMGYS 680
++ + QK ++ C ++ V YS
Sbjct: 179 LKPVVLQIECHPYLSQKPLITLCYDNAIAVTAYS 212
Score = 52.4 bits (120), Expect = 1e-05
Identities = 25/66 (37%), Positives = 38/66 (57%)
Frame = +1
Query: 58 MEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237
M P+ ++NG+ MP +GLGT+ +S + + V AID+GYRHFD A +Y
Sbjct: 1 MSTPNFLLSNGKNMPMLGLGTW---------RSPPEVVTQAVKDAIDIGYRHFDCAHIYG 51
Query: 238 TEQEIG 255
E ++G
Sbjct: 52 NEAQVG 57
>UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep:
Aldose reductase - Magnaporthe grisea (Rice blast
fungus) (Pyricularia grisea)
Length = 312
Score = 81.4 bits (192), Expect = 2e-14
Identities = 51/165 (30%), Positives = 88/165 (53%), Gaps = 15/165 (9%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
+ ++ + G+VKRED+F+ +K W T R E+ ++ SLK LGLDY+DLYL+HWPI +
Sbjct: 58 QGIREAISSGIVKREDLFVVSKCWATYTTRCELG--LDQSLKLLGLDYVDLYLVHWPILM 115
Query: 435 NADYS------HSD--------VDFMETWRGLEDAQRMG*LKASDCLTSTSSSW-RGC*K 569
N + + H+D + ++TW+ +E G KA +++ S +W
Sbjct: 116 NPEGNDEKFPKHADGSRDIIHTHNHVDTWKLMEKLPATGKTKAVG-VSNYSKAWLEQLLP 174
Query: 570 KALSNLMLFK*RVTSKTFQKEMVEFCQSESVVVMGYSPFRFPGXP 704
A + + + + Q+E+V+FC+ + + +M YSP G P
Sbjct: 175 HATTVPAVNQVENHPQLPQQELVDFCKEKGIHIMAYSPLGSTGGP 219
Score = 43.2 bits (97), Expect = 0.006
Identities = 25/60 (41%), Positives = 34/60 (56%)
Frame = +1
Query: 79 MNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
+N G +PA GLGT+ G GV+K + V+ AI GYR D A VY E+E+G+
Sbjct: 8 LNTGAKIPAFGLGTWQG--DKGVIK-------EAVLTAIKSGYRLIDGAYVYGNEEEVGQ 58
Score = 35.9 bits (79), Expect = 0.98
Identities = 16/39 (41%), Positives = 23/39 (58%)
Frame = +2
Query: 500 ANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGHLQ 616
A G K +G+SN++K LE++L T P Q+E H Q
Sbjct: 152 ATGKTKAVGVSNYSKAWLEQLLPHATTVPAVNQVENHPQ 190
>UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase
family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto
reductase family - Enterococcus faecalis (Streptococcus
faecalis)
Length = 279
Score = 80.2 bits (189), Expect = 5e-14
Identities = 46/132 (34%), Positives = 69/132 (52%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDF 467
+ RED+F+T+K+WN E QA NDSL++LGLDY+DLYL+HWP G N+ +
Sbjct: 72 LNREDLFVTSKVWNAHISYDETIQAFNDSLERLGLDYLDLYLIHWP-GNNS--------Y 122
Query: 468 METWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTSKTFQKEMVEFC 647
E+W+ LE G +KA A ++ + + K QKE+ +FC
Sbjct: 123 KESWQALETLYAEGKVKAIGVSNFQVHHLEDLLSYAKVVPVINQVELHPKLDQKEVRDFC 182
Query: 648 QSESVVVMGYSP 683
+ + V +SP
Sbjct: 183 EKHDIKVQAWSP 194
Score = 33.9 bits (74), Expect = 3.9
Identities = 20/62 (32%), Positives = 30/62 (48%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249
++ +NNG +P +GLG + + D++ VV I GYR DTA +Y E
Sbjct: 8 TVTLNNGTKIPGMGLGVF---------QIPDEETAKVVEEGIINGYRLIDTAQIYGNESG 58
Query: 250 IG 255
G
Sbjct: 59 TG 60
>UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep:
Aldehyde reductase 1 - Sporobolomyces salmonicolor
Length = 323
Score = 80.2 bits (189), Expect = 5e-14
Identities = 31/52 (59%), Positives = 44/52 (84%)
Frame = +3
Query: 273 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428
++E VKRED+FIT+KLWN HR +V A++D+LK+LGL+Y+DLYL+HWP+
Sbjct: 59 IKEAGVKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHWPV 110
Score = 33.9 bits (74), Expect = 3.9
Identities = 19/64 (29%), Positives = 31/64 (48%)
Frame = +1
Query: 64 VPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243
V + +N G + +G GT+ ++ ++ V AI+ GYRH D A VY +
Sbjct: 2 VGTTTLNTGASLELVGYGTW---------QAAPGEVGQGVKVAIETGYRHLDLAKVYSNQ 52
Query: 244 QEIG 255
E+G
Sbjct: 53 PEVG 56
>UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila
melanogaster|Rep: CG40064-PA - Drosophila melanogaster
(Fruit fly)
Length = 361
Score = 79.8 bits (188), Expect = 6e-14
Identities = 41/144 (28%), Positives = 81/144 (56%), Gaps = 12/144 (8%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG- 431
EA++ +++ G + RE+IF+TTKLWNT H +V + L+ LG YIDLYLMH+P+G
Sbjct: 75 EALRTQIKMGNISRENIFLTTKLWNTHHDPRDVRRICEKQLELLGFSYIDLYLMHFPVGY 134
Query: 432 ----------LNADYSHS-DVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKAL 578
++ D + ++D+++TWR +E+ ++G +++ + + +
Sbjct: 135 KYVCDEILMPMSGDELQTVEIDYLDTWRAMENLVKLGMVRSIGLSNFNMEQIQRIIQCSS 194
Query: 579 SNLMLFK*RVTSKTFQKEMVEFCQ 650
S ++ + + QK++V++C+
Sbjct: 195 SKPVVNQVEIWPGFLQKDLVDYCR 218
Score = 38.7 bits (86), Expect = 0.14
Identities = 18/36 (50%), Positives = 23/36 (63%)
Frame = +1
Query: 151 KSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
K + Q V AI+ G+RHFDTA YE E+EIG+
Sbjct: 40 KLRGYQCSAAVHCAIETGFRHFDTAYYYENEKEIGE 75
>UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase
1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent
oxidoreductase 1 - Oryza sativa subsp. japonica (Rice)
Length = 321
Score = 79.8 bits (188), Expect = 6e-14
Identities = 48/160 (30%), Positives = 75/160 (46%), Gaps = 10/160 (6%)
Frame = +3
Query: 255 EAVKMKVEEGVV-KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431
EAV V G++ R D+F+T+K+W + V A ++L+ LG+DY+DL L+HWP+
Sbjct: 63 EAVAEAVRRGLIASRADVFVTSKIWCSDLHAGRVVPAARETLRNLGMDYVDLLLVHWPVS 122
Query: 432 L---NADYSH------SDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSN 584
L N D+ D WRG+E+ R+G +A ++ A
Sbjct: 123 LTPGNYDFPFPKEVILPSFDMEGVWRGMEECHRLGLARAIGVSNFSAKKLEQLLSLAAVR 182
Query: 585 LMLFK*RVTSKTFQKEMVEFCQSESVVVMGYSPFRFPGXP 704
+ + V Q+ + E C+ E V + GYSP G P
Sbjct: 183 PAVNQVEVNPMWQQRTLREVCRREGVQLCGYSPLGAKGTP 222
Score = 43.2 bits (97), Expect = 0.006
Identities = 27/70 (38%), Positives = 42/70 (60%)
Frame = +1
Query: 49 ASTMEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTAS 228
A+ EVP+ ++ + MP +G+GT F S+D ++RAI++GYRHFDTA
Sbjct: 2 ATIPEVPASELI--QTMPRVGMGT-AAFP---FTSSEDTTA--AMLRAIELGYRHFDTAR 53
Query: 229 VYETEQEIGK 258
+Y TE +G+
Sbjct: 54 IYATEGCVGE 63
>UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30;
Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus
(Mouse)
Length = 316
Score = 79.4 bits (187), Expect = 8e-14
Identities = 47/163 (28%), Positives = 77/163 (47%), Gaps = 13/163 (7%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
EA++ K++E VKRED+FI +KLW+T ++ V +A ++L L LDY+DLYL+HWP G
Sbjct: 57 EAIQEKIQEKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGF 116
Query: 435 NA-----------DYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALS 581
+ S F++ W +E+ G +KA K
Sbjct: 117 QSGNVFLPTDDKGSILSSKYTFLDAWEAMEELVDQGLVKALGVSNFNHFQIERLLNKPGL 176
Query: 582 NLMLFK*RVTSKTF--QKEMVEFCQSESVVVMGYSPFRFPGXP 704
+V + Q+++ ++C S+ + + YSP P P
Sbjct: 177 KHKPVTNQVECHPYLTQEKLTQYCHSKGITITAYSPLGSPDRP 219
Score = 48.0 bits (109), Expect = 2e-04
Identities = 25/57 (43%), Positives = 33/57 (57%)
Frame = +1
Query: 88 GRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
G MP +GLGT+ KS ++R+ V AID GYRH D A VY+ E E+G+
Sbjct: 10 GAKMPIVGLGTW---------KSPPAKVREAVKVAIDAGYRHIDCAYVYQNESEVGE 57
Score = 34.7 bits (76), Expect = 2.3
Identities = 17/37 (45%), Positives = 25/37 (67%), Gaps = 2/37 (5%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTI--KPDAIQIEGH 610
G+VK +G+SNFN Q+ER+L + + KP Q+E H
Sbjct: 152 GLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECH 188
>UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 -
Mycoplasma gallisepticum
Length = 289
Score = 79.0 bits (186), Expect = 1e-13
Identities = 46/145 (31%), Positives = 74/145 (51%), Gaps = 4/145 (2%)
Frame = +3
Query: 264 KMKVEEGV----VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431
++ V +G+ V R++IFIT+K+WN +A + LK L L+Y+DL L+HWPIG
Sbjct: 62 QLSVSQGIKLSGVNRKEIFITSKIWNDDKGYESTKKAFHKILKDLDLEYLDLLLIHWPIG 121
Query: 432 LNADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVT 611
+ +V+ +TW+ +E+ G +KA K A M+ +
Sbjct: 122 KGFKDNWQEVN-AQTWKAMEEFYLEGKIKAIGLSNFLVHHIEALKKSAKILPMVNQLEFH 180
Query: 612 SKTFQKEMVEFCQSESVVVMGYSPF 686
Q E+VE+CQ ++VV +SPF
Sbjct: 181 PGYLQPEIVEYCQKNNIVVQAWSPF 205
Score = 42.3 bits (95), Expect = 0.011
Identities = 26/73 (35%), Positives = 39/73 (53%), Gaps = 4/73 (5%)
Frame = +1
Query: 52 STMEVPSLKMN---NGRXMPAIGLGTYLGFDQNGVVKSKD-KQLRDVVMRAIDVGYRHFD 219
+T ++ +K N N MP+IG GTY K +D KQ + V A++VGYRH D
Sbjct: 4 TTKKIKVMKYNLLANNYKMPSIGFGTY---------KLEDGKQTVEAVKTALEVGYRHLD 54
Query: 220 TASVYETEQEIGK 258
A +YE + + +
Sbjct: 55 CAEIYENQLSVSQ 67
>UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Opitutaceae bacterium TAV2
Length = 347
Score = 79.0 bits (186), Expect = 1e-13
Identities = 46/152 (30%), Positives = 75/152 (49%), Gaps = 12/152 (7%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI------GLNADYS 449
++RED++IT+KLWN +H +V A SL+ LGLDY+DLYL+HWP G +
Sbjct: 86 IRREDLWITSKLWNDKHAEADVIPAFEKSLRDLGLDYLDLYLIHWPFPNFHPPGCDVSSR 145
Query: 450 HSD------VDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVT 611
D +FM+TWR LE G ++ T + + + A + + +
Sbjct: 146 SPDARPYIHAEFMKTWRQLETLHDRGLVRHIGTSNMTIAKLQLLLRDARVRPAVNEMELH 205
Query: 612 SKTFQKEMVEFCQSESVVVMGYSPFRFPGXPD 707
Q + ++ + ++V +GY P PG P+
Sbjct: 206 PHFQQPALFDYVRVRNIVPVGYCPLGSPGRPE 237
Score = 49.2 bits (112), Expect = 1e-04
Identities = 26/65 (40%), Positives = 39/65 (60%)
Frame = +1
Query: 61 EVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240
++P + +G MPAIG+GT+ G D + ++ V A ++GYRHFD A+VY
Sbjct: 15 KIPQRTLASGARMPAIGMGTF-GSDH-----AAPGEVAASVYAAAELGYRHFDCAAVYSN 68
Query: 241 EQEIG 255
E+EIG
Sbjct: 69 EREIG 73
>UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep:
Yarrowia lipolytica chromosome B of strain CLIB122 of
Yarrowia lipolytica - Yarrowia lipolytica (Candida
lipolytica)
Length = 337
Score = 79.0 bits (186), Expect = 1e-13
Identities = 53/162 (32%), Positives = 86/162 (53%), Gaps = 14/162 (8%)
Frame = +3
Query: 261 VKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA 440
+K +E+GV KREDIF+TTK+W T H R E + ++ SL++LGLDY+D+ L+HWP+ LN
Sbjct: 89 IKRAMEKGV-KREDIFVTTKIWVTYHDRVE--ENLDMSLERLGLDYVDMLLIHWPVPLNP 145
Query: 441 D-----Y-----SHSDVDFM----ETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKAL 578
+ Y D+D +TW+ +E + G K+ + K+A
Sbjct: 146 NGNDPVYPLRPDGSRDIDESGSQPKTWKQMEAVLKTGKTKSIGVSNFSIPYLEELLKEAE 205
Query: 579 SNLMLFK*RVTSKTFQKEMVEFCQSESVVVMGYSPFRFPGXP 704
+ + + Q E++EFC+ ++V+ +SPF G P
Sbjct: 206 VVPAVNQVELHPLLPQLELMEFCKKNNIVMTAFSPFGSVGGP 247
Score = 41.9 bits (94), Expect = 0.015
Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 1/68 (1%)
Frame = +1
Query: 55 TMEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAI-DVGYRHFDTASV 231
TM +NNG+ +PAIGLGT+ KS +++ V A+ + GYRH DTA
Sbjct: 28 TMTSLDFTLNNGKTIPAIGLGTW---------KSTTEEVAGAVECALTEGGYRHIDTAFN 78
Query: 232 YETEQEIG 255
Y E +G
Sbjct: 79 YRNEDAVG 86
Score = 33.9 bits (74), Expect = 3.9
Identities = 16/35 (45%), Positives = 21/35 (60%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
G K IG+SNF+ LE +LKE + P Q+E H
Sbjct: 182 GKTKSIGVSNFSIPYLEELLKEAEVVPAVNQVELH 216
>UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus
tropicalis|Rep: LOC594893 protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 345
Score = 78.2 bits (184), Expect = 2e-13
Identities = 49/161 (30%), Positives = 79/161 (49%), Gaps = 13/161 (8%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
+A + K +G +KRED+F T+KLWNT H+ V A+ +L L +DY+DLYL+H P+
Sbjct: 85 QAFREKFADGTLKREDLFYTSKLWNTFHQPHLVRPALEKTLSFLQMDYVDLYLIHMPMSF 144
Query: 435 ---------NAD--YSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALS 581
N D + D ++TW+ LE+ + G +K+ K
Sbjct: 145 KPAEELFPKNEDGTCAFDQPDLLQTWQALEECRDAGLVKSIGVSNFNRRQLEMILNKPGL 204
Query: 582 NLMLFK*RVTSKTF--QKEMVEFCQSESVVVMGYSPFRFPG 698
++ + QK+M+EFC+S+ +VV+ Y PG
Sbjct: 205 KYKPVCNQIECHPYLNQKQMLEFCKSKDIVVVAYGVLGSPG 245
Score = 39.5 bits (88), Expect = 0.079
Identities = 22/41 (53%), Positives = 27/41 (65%), Gaps = 2/41 (4%)
Frame = +2
Query: 494 CSANGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEGH 610
C G+VK IG+SNFN++QLE +L K G KP QIE H
Sbjct: 176 CRDAGLVKSIGVSNFNRRQLEMILNKPGLKYKPVCNQIECH 216
Score = 39.1 bits (87), Expect = 0.10
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 15/78 (19%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFD---------------QNGVVKSKDKQLRDVVMRAIDVG 204
S+++++GR MP + GT+ F ++G KS +R A+D+G
Sbjct: 8 SIQLHDGRWMPVVAFGTFYPFTFPGDSQANPGHCAGTKHGTEKSFIDDVRVATKMALDLG 67
Query: 205 YRHFDTASVYETEQEIGK 258
YRH D A +Y +E +G+
Sbjct: 68 YRHVDGAFLYSSETGVGQ 85
>UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 286
Score = 78.2 bits (184), Expect = 2e-13
Identities = 36/83 (43%), Positives = 52/83 (62%), Gaps = 2/83 (2%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW--PI 428
E+V + + V RED+F+TTKLWN H +A++ SL KLGLDY+DLYL+HW P
Sbjct: 60 ESVGKAIADSGVAREDLFVTTKLWNADHGYDAAKKALDTSLAKLGLDYVDLYLIHWPNPA 119
Query: 429 GLNADYSHSDVDFMETWRGLEDA 497
+ ++ + D TWR +E+A
Sbjct: 120 AMRDNWEQLNAD---TWRAMEEA 139
Score = 45.2 bits (102), Expect = 0.002
Identities = 25/71 (35%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
Frame = +1
Query: 49 ASTMEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLR-DVVMRAIDVGYRHFDTA 225
A T + +NNG +P +G GT+ ++ D Q+ D V+ A+ GYRH DTA
Sbjct: 3 ALTKLTDTYTLNNGTKIPIVGFGTW---------QTPDGQVAYDSVLAALKAGYRHIDTA 53
Query: 226 SVYETEQEIGK 258
+ Y E+ +GK
Sbjct: 54 AAYGNEESVGK 64
>UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC
700755|Rep: YvgN - Psychroflexus torquis ATCC 700755
Length = 280
Score = 78.2 bits (184), Expect = 2e-13
Identities = 46/145 (31%), Positives = 77/145 (53%), Gaps = 2/145 (1%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLW--NTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428
EAV ++ V RE+IF+TTKLW N +++T +A +++SL+KL L+YIDLYL+HWP
Sbjct: 52 EAVGKAIKARGVLREEIFVTTKLWRENLGYKQTRIA--LDESLRKLDLNYIDLYLIHWPA 109
Query: 429 GLNADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RV 608
+Y +TWR +E+ Q G +K+ + A + + +
Sbjct: 110 NA-INYKDWQKTNADTWRAMEELQAEGKIKSLGVSNFWPEHLEALFQTAKVSPSVNQIEF 168
Query: 609 TSKTFQKEMVEFCQSESVVVMGYSP 683
+Q ++ EFC++ + V +SP
Sbjct: 169 HPGYWQPQVTEFCKNHGIAVESWSP 193
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/60 (35%), Positives = 35/60 (58%)
Frame = +1
Query: 79 MNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
+N+G +P +G GTY ++ G+ KS K A+ +GYR DT ++Y+ E+ +GK
Sbjct: 5 LNDGNRIPIVGFGTYKANEEEGI-KSIQKS-------ALTLGYRLIDTVAIYQNEEAVGK 56
>UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452
protein; n=6; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to LOC553452 protein -
Strongylocentrotus purpuratus
Length = 321
Score = 77.8 bits (183), Expect = 2e-13
Identities = 47/161 (29%), Positives = 79/161 (49%), Gaps = 14/161 (8%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP--- 425
+ +K K+++G +KRED+F+T+KLW T + V + SL LGL Y+DL+L+H P
Sbjct: 60 DGIKAKIDDGTIKREDLFVTSKLWVTDSHPSRVEPSCRQSLSDLGLAYLDLFLIHCPTSA 119
Query: 426 IGLNADYSHSD---------VDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKAL 578
+G + D +D+++TWR +E G ++A T + +
Sbjct: 120 VGGKGPFPMDDNGLFIGDDTIDYVDTWRIMESLVDKGLVRAIGVSNFTVAQIQRV-LDLP 178
Query: 579 SNLMLFK*RVTSKTF--QKEMVEFCQSESVVVMGYSPFRFP 695
+ +V F Q E++EFC+ + + V YSP P
Sbjct: 179 PKYPIANVQVECHPFLAQNELIEFCKKQGITVTAYSPLGSP 219
Score = 40.3 bits (90), Expect = 0.045
Identities = 21/56 (37%), Positives = 32/56 (57%)
Frame = +1
Query: 88 GRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
GR +P +G GT+ + K +++ V+ AID GYRH D AS+Y E+ +G
Sbjct: 13 GRKLPLLGFGTW---------QIKPEEVGRVIETAIDCGYRHIDEASLYGNEKGVG 59
>UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase
family; n=2; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 305
Score = 77.8 bits (183), Expect = 2e-13
Identities = 42/151 (27%), Positives = 76/151 (50%), Gaps = 3/151 (1%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
+ +K + +G VKRE++F+TTKLW+T + +V A +SLKKL L+Y+DLY++H P+
Sbjct: 57 DGIKSAIAKGYVKREELFVTTKLWSTDKHKEDVRPACLESLKKLQLEYLDLYIIHIPLTA 116
Query: 435 N---ADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*R 605
+ +++ + ETWR +E G +K+ A + +
Sbjct: 117 DKKTGEFTEEIIPIEETWREMEKLVEEGLVKSIGVSNFNIKKLEELLAIAKIQPAVNQFE 176
Query: 606 VTSKTFQKEMVEFCQSESVVVMGYSPFRFPG 698
+ ++ +FC+ ++ + GY P PG
Sbjct: 177 FHIYYQRPKLHQFCKKHNIHITGYCPLGNPG 207
Score = 39.9 bits (89), Expect = 0.060
Identities = 24/59 (40%), Positives = 31/59 (52%)
Frame = +1
Query: 79 MNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
+NNG +P +GLGT++ NG V V AI GYRH D A Y E+E+G
Sbjct: 7 LNNGYKIPKLGLGTWMS--ANGEVGK-------AVEIAIKNGYRHIDCAKAYGNEKEVG 56
Score = 37.1 bits (82), Expect = 0.42
Identities = 17/36 (47%), Positives = 24/36 (66%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGHL 613
G+VK IG+SNFN ++LE +L I+P Q E H+
Sbjct: 144 GLVKSIGVSNFNIKKLEELLAIAKIQPAVNQFEFHI 179
>UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase;
n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid
dehydrogenase - Xenopus tropicalis (Western clawed frog)
(Silurana tropicalis)
Length = 324
Score = 77.8 bits (183), Expect = 2e-13
Identities = 45/154 (29%), Positives = 76/154 (49%), Gaps = 13/154 (8%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL- 434
A++ K+ +G VKRED+F T KLW+T H V A+ SLK L LDY+DL+++H P+
Sbjct: 65 AIRAKIADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPMEFK 124
Query: 435 ----------NADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSN 584
N + + + D +TW+ LE + G +++
Sbjct: 125 PGDDLFPADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIGVSNFNHKQLELILNMPGLK 184
Query: 585 LMLFK*RVTSKTF--QKEMVEFCQSESVVVMGYS 680
+V + Q +++EFC+S+ +V++GYS
Sbjct: 185 YKPVCNQVECHVYLNQSKLLEFCKSKDIVLVGYS 218
Score = 46.0 bits (104), Expect = 0.001
Identities = 24/62 (38%), Positives = 33/62 (53%)
Frame = +1
Query: 73 LKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252
+++N+G MP IG GTY K + AIDVGYRH D A +Y E+E+
Sbjct: 9 VELNDGHKMPVIGFGTY------APPKFPKSLAEEGTKVAIDVGYRHIDCAFLYGNEEEV 62
Query: 253 GK 258
G+
Sbjct: 63 GR 64
Score = 36.7 bits (81), Expect = 0.56
Identities = 18/43 (41%), Positives = 27/43 (62%), Gaps = 2/43 (4%)
Frame = +2
Query: 491 RCSANGIVKGIGLSNFNKQQLERVLKEGTI--KPDAIQIEGHL 613
+C G+V+ IG+SNFN +QLE +L + KP Q+E H+
Sbjct: 154 KCKDAGLVRSIGVSNFNHKQLELILNMPGLKYKPVCNQVECHV 196
>UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p -
Drosophila melanogaster (Fruit fly)
Length = 311
Score = 77.8 bits (183), Expect = 2e-13
Identities = 38/93 (40%), Positives = 56/93 (60%), Gaps = 8/93 (8%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG- 431
+A+ K+ EGVV RE++F+TTKL H V +A SL LGL+Y+DLYLMH P+G
Sbjct: 60 QAISEKIAEGVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMPVGQ 119
Query: 432 -------LNADYSHSDVDFMETWRGLEDAQRMG 509
++ +DVD+++TWR +E +G
Sbjct: 120 KFHNDSNVHGTLELTDVDYLDTWREMEKLVDLG 152
Score = 61.3 bits (142), Expect = 2e-08
Identities = 28/64 (43%), Positives = 41/64 (64%)
Frame = +1
Query: 67 PSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 246
P++++NNGR MP +GLGT+ F+ + ++ A+DVGYRH DTA VYE E
Sbjct: 6 PTIRLNNGREMPTLGLGTWKSFESDAYHSTR---------HALDVGYRHLDTAFVYENEA 56
Query: 247 EIGK 258
E+G+
Sbjct: 57 EVGQ 60
Score = 38.7 bits (86), Expect = 0.14
Identities = 18/35 (51%), Positives = 22/35 (62%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
G+ + IGLSNFN Q ERVL I+P Q+E H
Sbjct: 152 GLTRSIGLSNFNAAQTERVLANCRIRPVVNQVECH 186
>UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3;
Lactobacillus|Rep: 2,5-didehydrogluconate reductase -
Lactobacillus reuteri 100-23
Length = 288
Score = 77.4 bits (182), Expect = 3e-13
Identities = 34/89 (38%), Positives = 53/89 (59%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
EAV +++ +KRED+F+T+KLWNT + +A ++L +L +DY+DLYL+HWP
Sbjct: 59 EAVGKGIKDSGIKREDLFVTSKLWNTNRGYEQTKKAFQETLDRLQMDYLDLYLIHWPANE 118
Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKA 521
+ ETWR +ED G ++A
Sbjct: 119 KQFGDDAAKINAETWRAMEDLYNEGKIRA 147
Score = 44.4 bits (100), Expect = 0.003
Identities = 22/63 (34%), Positives = 33/63 (52%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249
+ +NNG +P +G GT+ ++ V AI+ GYRH DTA+VY E+
Sbjct: 10 TFNLNNGVKIPCVGYGTF---------RTPADVAEQAVKEAIETGYRHIDTAAVYGNEEA 60
Query: 250 IGK 258
+GK
Sbjct: 61 VGK 63
>UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core
eudicotyledons|Rep: Aldose reductase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 316
Score = 77.4 bits (182), Expect = 3e-13
Identities = 46/156 (29%), Positives = 78/156 (50%), Gaps = 9/156 (5%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL- 434
A+ + G V+R+D+F+T+KLW++ H + A+ +LK +GLDY+D YL+HWPI L
Sbjct: 61 ALGQAISYGTVQRDDLFVTSKLWSSDHH--DPISALIQTLKTMGLDYLDNYLVHWPIKLK 118
Query: 435 --------NADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLM 590
D D+ ETW+G+E MG ++ +S A +
Sbjct: 119 PGVSEPIPKEDEFEKDLGIEETWQGMERCLEMGLCRSIGVSNFSSKKIFDLLDFASVSPS 178
Query: 591 LFK*RVTSKTFQKEMVEFCQSESVVVMGYSPFRFPG 698
+ + + Q+++ + C+ ++ V GYSP PG
Sbjct: 179 VNQVEMHPLWRQRKLRKVCEENNIHVSGYSPLGGPG 214
Score = 43.6 bits (98), Expect = 0.005
Identities = 22/61 (36%), Positives = 35/61 (57%), Gaps = 1/61 (1%)
Frame = +1
Query: 76 KMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLR-DVVMRAIDVGYRHFDTASVYETEQEI 252
++ G +P +G+GTY KD++ V +AI +GYRHFDTA +Y +E+ +
Sbjct: 7 RLRCGETIPLLGMGTYC--------PQKDRESTISAVHQAIKIGYRHFDTAKIYGSEEAL 58
Query: 253 G 255
G
Sbjct: 59 G 59
Score = 33.1 bits (72), Expect = 6.9
Identities = 13/40 (32%), Positives = 24/40 (60%)
Frame = +2
Query: 491 RCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
RC G+ + IG+SNF+ +++ +L ++ P Q+E H
Sbjct: 146 RCLEMGLCRSIGVSNFSSKKIFDLLDFASVSPSVNQVEMH 185
>UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44;
Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo
sapiens (Human)
Length = 325
Score = 77.4 bits (182), Expect = 3e-13
Identities = 50/155 (32%), Positives = 72/155 (46%), Gaps = 12/155 (7%)
Frame = +3
Query: 255 EAVKMKVEEG-VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431
EA+K V G V RE++F+T+KLWNT+H +V A+ +L L L+Y+DLYLMHWP
Sbjct: 58 EALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYA 117
Query: 432 L---------NAD--YSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKAL 578
NAD + + ETW+ LE G ++A S A
Sbjct: 118 FERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVAS 177
Query: 579 SNLMLFK*RVTSKTFQKEMVEFCQSESVVVMGYSP 683
+ + Q E++ CQ+ + V YSP
Sbjct: 178 VRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSP 212
Score = 48.0 bits (109), Expect = 2e-04
Identities = 26/67 (38%), Positives = 38/67 (56%)
Frame = +1
Query: 58 MEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237
M + ++ G+ MP IGLGT+ KS+ Q++ V A+ VGYRH D A++Y
Sbjct: 1 MAASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYG 51
Query: 238 TEQEIGK 258
E EIG+
Sbjct: 52 NEPEIGE 58
>UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 339
Score = 77.0 bits (181), Expect = 4e-13
Identities = 42/153 (27%), Positives = 74/153 (48%), Gaps = 16/153 (10%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI------------- 428
V+RE++F+++K+WNT H R Q I++ L+ Y+DL ++HWP
Sbjct: 70 VRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIHWPFGWAEDEPPGERGL 129
Query: 429 ---GLNADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK 599
G N +SDVD++ETW+ LEDA R G +++ K L + +
Sbjct: 130 WPRGANGKMRYSDVDYLETWKALEDAHRSGKIRSIGLANFNIGQVEQVWTKGLIKPAVLQ 189
Query: 600 *RVTSKTFQKEMVEFCQSESVVVMGYSPFRFPG 698
+ Q+E+ +FC+ + +++ + PG
Sbjct: 190 VEMNPFLDQEEIRQFCREKGIILTAFMLTGNPG 222
Score = 33.5 bits (73), Expect = 5.2
Identities = 19/61 (31%), Positives = 36/61 (59%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249
++ +N+G MP IG GT+ +N + ++RD A++ GYRH D+A ++ ++E
Sbjct: 6 TVTLNSGYEMPVIGYGTWQ-LPKNLAAE----RVRD----ALEAGYRHIDSALSFKNQEE 56
Query: 250 I 252
+
Sbjct: 57 V 57
>UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium
discoideum|Rep: Aldehyde reductase - Dictyostelium
discoideum AX4
Length = 297
Score = 76.6 bits (180), Expect = 6e-13
Identities = 46/145 (31%), Positives = 68/145 (46%), Gaps = 10/145 (6%)
Frame = +3
Query: 279 EGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSD 458
E VKRED+FIT+KLWNT H++ V A+ +L LGL Y+DLYL+HWP+ +Y+ +D
Sbjct: 66 EATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVHWPVAF--EYTSND 123
Query: 459 ----------VDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RV 608
V ETW +E G +K+ A + +
Sbjct: 124 IQTSGSTQEFVSIRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYARIKPAANQVEL 183
Query: 609 TSKTFQKEMVEFCQSESVVVMGYSP 683
Q E+ +FC ++ + YSP
Sbjct: 184 HPFLSQPELKKFCDKHNIHLTAYSP 208
Score = 46.0 bits (104), Expect = 0.001
Identities = 23/64 (35%), Positives = 37/64 (57%)
Frame = +1
Query: 67 PSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 246
PS K+++G +P +G GT+ K++ + V A+D GYRH D A+VY E+
Sbjct: 3 PSFKLSSGHKIPLVGFGTW---------KAETTLVGKAVEVALDAGYRHIDCAAVYLNEK 53
Query: 247 EIGK 258
E+G+
Sbjct: 54 EVGE 57
Score = 41.5 bits (93), Expect = 0.020
Identities = 21/35 (60%), Positives = 23/35 (65%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
G+VK IGLSNFN Q L VL IKP A Q+E H
Sbjct: 150 GLVKSIGLSNFNVQGLMEVLSYARIKPAANQVELH 184
>UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 303
Score = 75.8 bits (178), Expect = 1e-12
Identities = 47/143 (32%), Positives = 71/143 (49%), Gaps = 7/143 (4%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI-----GLNADYSH 452
+ RED+FI +KL T HR V + SL++LGLDY+DLYLMH P+ G D S
Sbjct: 66 INREDVFIVSKLGPTFHRPEAVEKGCRLSLERLGLDYVDLYLMHTPVAARDSGDGNDRSE 125
Query: 453 SD--VDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTSKTFQ 626
D V +ETW+ LE+ QR G +++ ++ + + Q
Sbjct: 126 IDDEVTPLETWKALEECQRKGLVRSIGVSNFNEEQLMEIVTHGSIRPVVNQVECSIGFHQ 185
Query: 627 KEMVEFCQSESVVVMGYSPFRFP 695
++ +FC E +++M YSP P
Sbjct: 186 VKLRKFCNREGILIMAYSPLGKP 208
Score = 45.6 bits (103), Expect = 0.001
Identities = 26/62 (41%), Positives = 33/62 (53%)
Frame = +1
Query: 73 LKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252
L +NNG +P IGLGTY +GV K A++ GYR DTA VY EQ +
Sbjct: 2 LALNNGHSIPPIGLGTYKITGSDGVAAIKS---------AVEFGYRLIDTAFVYNNEQVV 52
Query: 253 GK 258
G+
Sbjct: 53 GQ 54
Score = 42.3 bits (95), Expect = 0.011
Identities = 16/37 (43%), Positives = 26/37 (70%)
Frame = +2
Query: 494 CSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIE 604
C G+V+ IG+SNFN++QL ++ G+I+P Q+E
Sbjct: 142 CQRKGLVRSIGVSNFNEEQLMEIVTHGSIRPVVNQVE 178
>UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyces
cerevisiae YDR368w YPR1; n=1; Kluyveromyces lactis|Rep:
Similarities with sp|Q12458 Saccharomyces cerevisiae
YDR368w YPR1 - Kluyveromyces lactis (Yeast) (Candida
sphaerica)
Length = 127
Score = 75.8 bits (178), Expect = 1e-12
Identities = 32/59 (54%), Positives = 46/59 (77%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
AV + + + RE+IF+TTKLWNTQ R + A A+N+SL++LGLDY+DL+L+HWP+ L
Sbjct: 7 AVGKGIRDSGIPREEIFVTTKLWNTQQR--DPASALNESLERLGLDYVDLFLIHWPVPL 63
>UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus acidophilus
Length = 285
Score = 75.4 bits (177), Expect = 1e-12
Identities = 33/89 (37%), Positives = 58/89 (65%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
++V +++ + R ++FITTKLWN+ H + +AI+ SL L LDY+D+YL+HWP
Sbjct: 59 DSVGRAIQKSGINRHELFITTKLWNSDHGYEKTKKAIDQSLLDLKLDYLDMYLIHWPNPS 118
Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKA 521
+ ++++ E+WR +E+A R G ++A
Sbjct: 119 SMRDHWAEIN-AESWRAMEEAVRAGKIRA 146
Score = 42.3 bits (95), Expect = 0.011
Identities = 24/60 (40%), Positives = 33/60 (55%)
Frame = +1
Query: 79 MNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
+NNG +P IG GT+ D G V + V+ A++ GYRH DTAS Y E +G+
Sbjct: 12 LNNGVKIPIIGFGTWQTPD--GEVAEES------VLAALNCGYRHIDTASAYGNEDSVGR 63
>UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1;
Arabidopsis thaliana|Rep: Uncharacterized protein
At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress)
Length = 283
Score = 75.4 bits (177), Expect = 1e-12
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 7/84 (8%)
Frame = +3
Query: 261 VKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP----- 425
+K E+ VVKRED+FIT+KLW T H +V +A+N +LK L L+Y+DLYL+HWP
Sbjct: 62 LKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKK 121
Query: 426 --IGLNADYSHSDVDFMETWRGLE 491
+G+ + + VD TW+ +E
Sbjct: 122 GSVGIKPE-NLLPVDIPSTWKAME 144
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/60 (40%), Positives = 33/60 (55%)
Frame = +1
Query: 76 KMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
K+N G P++GLGT+ G+V D V A+ +GYRH D A +Y E+EIG
Sbjct: 9 KLNTGAKFPSVGLGTWQA--SPGLVG-------DAVAAAVKIGYRHIDCAQIYGNEKEIG 59
>UniRef50_P22045 Cluster: Probable reductase; n=101; cellular
organisms|Rep: Probable reductase - Leishmania major
Length = 284
Score = 75.4 bits (177), Expect = 1e-12
Identities = 35/79 (44%), Positives = 48/79 (60%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
E+V + V RED+FITTKLWNT+ A +S +KLG+DYIDLYL+HWP G
Sbjct: 58 ESVGAGLRASGVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRGK 117
Query: 435 NADYSHSDVDFMETWRGLE 491
+ S ++++WR E
Sbjct: 118 DI-LSKEGKKYLDSWRAFE 135
Score = 36.3 bits (80), Expect = 0.74
Identities = 19/59 (32%), Positives = 30/59 (50%)
Frame = +1
Query: 79 MNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
++NG MP GLG + + + V A+ GYRH DTA++Y+ E+ +G
Sbjct: 11 LSNGVKMPQFGLGVWQS--------PAGEVTENAVNWALCAGYRHIDTAAIYKNEESVG 61
>UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2;
Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus
sp. (strain CC9311)
Length = 336
Score = 74.9 bits (176), Expect = 2e-12
Identities = 40/153 (26%), Positives = 76/153 (49%), Gaps = 10/153 (6%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
+A++ ++ + R +++IT+KLW+ H + V A++ SL+ LG+DY++LYL+HWP+G+
Sbjct: 74 DAIRDAIQNHEITRSELWITSKLWSNCHGKNHVEAALSQSLQNLGVDYLNLYLIHWPVGI 133
Query: 435 NADYSHSD-VD---------FMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSN 584
+ + ++ VD ETW +E + G K T +
Sbjct: 134 RPEKTFAESVDDLLTPEESPISETWEAMESTRDKGLTKHIGVSNFTVKKLQQLVSHCKQK 193
Query: 585 LMLFK*RVTSKTFQKEMVEFCQSESVVVMGYSP 683
+ + Q ++E+C SE +++ YSP
Sbjct: 194 PEVNQVEHHPLLQQPTLIEYCASEEILITAYSP 226
Score = 49.6 bits (113), Expect = 7e-05
Identities = 29/67 (43%), Positives = 39/67 (58%)
Frame = +1
Query: 55 TMEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY 234
TM+ SL +NG MP +GLGT KS+ +Q+ V AI +GYRH D AS+Y
Sbjct: 18 TMQYASL--SNGDRMPLLGLGTG---------KSESRQVYKSVREAIKIGYRHIDCASIY 66
Query: 235 ETEQEIG 255
E+E+G
Sbjct: 67 GNEEEVG 73
>UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13;
Pezizomycotina|Rep: Aldehyde reductase - Coccidioides
posadasii
Length = 314
Score = 74.9 bits (176), Expect = 2e-12
Identities = 36/100 (36%), Positives = 58/100 (58%), Gaps = 11/100 (11%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
+A+ + + R+++FIT+KLWN +HR +V QAI+ SLK L +DY+DLYLMHWP
Sbjct: 55 KAIGRALARSRLSRDELFITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMHWPAAF 114
Query: 435 -----------NADYSHSDVDFMETWRGLEDAQRMG*LKA 521
+ D+D+++T++ +E + G KA
Sbjct: 115 APGDDMFPKDSQGNSKTVDIDYVDTYKAMEKLVKSGKTKA 154
Score = 49.6 bits (113), Expect = 7e-05
Identities = 26/63 (41%), Positives = 37/63 (58%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249
+ ++N G +PAIG GT+ D+N D V+ A+ GYRH DTA+VY TE+
Sbjct: 7 TFRLNTGEDIPAIGFGTWQ--DENAQ--------EDAVLTALSAGYRHIDTAAVYGTEKA 56
Query: 250 IGK 258
IG+
Sbjct: 57 IGR 59
Score = 37.1 bits (82), Expect = 0.42
Identities = 16/36 (44%), Positives = 26/36 (72%)
Frame = +2
Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
+G K IG+SNF+K ++ER+L+ +I P +Q+E H
Sbjct: 149 SGKTKAIGISNFSKGEMERLLESCSIVPAVMQMELH 184
>UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5;
Saccharomycetales|Rep: D-arabinose dehydrogenase -
Pichia stipitis (Yeast)
Length = 326
Score = 74.9 bits (176), Expect = 2e-12
Identities = 33/63 (52%), Positives = 47/63 (74%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
+A+K EEG+VKRED+FITTK+W + R E ++++ SL LGLDY+DL+L HWP+ L
Sbjct: 63 QALKQLFEEGIVKREDLFITTKVWPSFWRNPE--KSLDKSLADLGLDYVDLFLQHWPVVL 120
Query: 435 NAD 443
+ D
Sbjct: 121 HGD 123
Score = 46.4 bits (105), Expect = 7e-04
Identities = 24/60 (40%), Positives = 36/60 (60%)
Frame = +1
Query: 79 MNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
++NG+ +PA+GLGT V +L++ V+ A+ GYRH DTA Y TE+ IG+
Sbjct: 12 LSNGKTIPALGLGT--------VPPEDPHELKEQVITAVKAGYRHIDTAWYYGTEEYIGQ 63
>UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 360
Score = 74.5 bits (175), Expect = 2e-12
Identities = 35/82 (42%), Positives = 58/82 (70%), Gaps = 5/82 (6%)
Frame = +3
Query: 258 AVKMKVEEGV----VKREDIFITTKLWNTQHRRTE-VAQAINDSLKKLGLDYIDLYLMHW 422
AV +EEG+ +KREDI++T+KLWN H E V + +N +L+ LGL+Y+DLYL+HW
Sbjct: 82 AVGRGIEEGLKRAGLKREDIWVTSKLWNDHHGSYENVEKGLNQTLQDLGLEYLDLYLIHW 141
Query: 423 PIGLNADYSHSDVDFMETWRGL 488
PIG +++ ++D ++T++ +
Sbjct: 142 PIGFSSN-GAKNLDHVQTYKSM 162
Score = 32.7 bits (71), Expect = 9.1
Identities = 18/53 (33%), Positives = 27/53 (50%)
Frame = +1
Query: 100 PAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
P IG GT+ +K + + V AI++GYR D A+VY E +G+
Sbjct: 40 PLIGFGTWN-------LKVSPENTTEAVAYAIEIGYRQIDCAAVYGNEVAVGR 85
>UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 323
Score = 74.5 bits (175), Expect = 2e-12
Identities = 44/148 (29%), Positives = 76/148 (51%), Gaps = 11/148 (7%)
Frame = +3
Query: 273 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG------- 431
+ + V RE+IFIT KLWNT+H +V A++ +L+ LG+ Y+DLYLMHWP
Sbjct: 61 IRKSGVPREEIFITGKLWNTKHAPEDVEPALDKTLQDLGVAYLDLYLMHWPCAFKGGDKW 120
Query: 432 --LNAD--YSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK 599
LN D + +++D++ T+R +E G ++A + + +
Sbjct: 121 FPLNDDGVFDLANIDYITTYRAMEKLLATGKVRAIGVSNFNIRRLEELLGQVSVVPAVNQ 180
Query: 600 *RVTSKTFQKEMVEFCQSESVVVMGYSP 683
Q ++++FCQS+ +++ YSP
Sbjct: 181 IEAHPYLQQPDLLQFCQSKGILIEAYSP 208
Score = 42.7 bits (96), Expect = 0.009
Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
Frame = +1
Query: 58 MEVPS-LKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY 234
M +PS +N G +PA+G GT+ ++K ++ + V A+ GYRH D A++Y
Sbjct: 1 MSLPSHFTINTGAKIPAVGFGTW---------QAKPLEVENAVEVALREGYRHIDCAAIY 51
Query: 235 ETEQEIG 255
E E+G
Sbjct: 52 RNETEVG 58
Score = 37.1 bits (82), Expect = 0.42
Identities = 17/37 (45%), Positives = 25/37 (67%)
Frame = +2
Query: 500 ANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
A G V+ IG+SNFN ++LE +L + ++ P QIE H
Sbjct: 148 ATGKVRAIGVSNFNIRRLEELLGQVSVVPAVNQIEAH 184
>UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28;
Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza
sativa (Rice)
Length = 323
Score = 73.7 bits (173), Expect = 4e-12
Identities = 46/152 (30%), Positives = 73/152 (48%), Gaps = 9/152 (5%)
Frame = +3
Query: 255 EAVKMKVEEGVV-KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431
EA+ G+V RE++F+TTKLW TQ V ++ +SL+ L ++Y+DLYL+HWPI
Sbjct: 64 EAIAEATRRGLVASREEVFVTTKLWCTQCHPGLVLPSLRESLRNLQMEYVDLYLVHWPIS 123
Query: 432 LN-----ADYSHSDV---DFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNL 587
+ D DF WR +E+ R+G KA T+ A
Sbjct: 124 VKPGPPMLPVKREDAVPFDFEGVWRAMEECHRLGLAKAIGVSNFTTKHLDKLLAVATIPP 183
Query: 588 MLFK*RVTSKTFQKEMVEFCQSESVVVMGYSP 683
+ + + Q+ + E+C ++ + V YSP
Sbjct: 184 AVNQVEMNPVWQQRTVREYCAAKGIRVAAYSP 215
Score = 48.0 bits (109), Expect = 2e-04
Identities = 27/70 (38%), Positives = 43/70 (61%)
Frame = +1
Query: 49 ASTMEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTAS 228
A+ EV +L+ GR MPA+G+GT + S + + R + A++VG+RHFDTA+
Sbjct: 2 AAVPEV-ALRHGAGRPMPAVGVGT-----ADSAATSPETK-RGAALAALEVGFRHFDTAA 54
Query: 229 VYETEQEIGK 258
+Y TE +G+
Sbjct: 55 LYGTEAPLGE 64
>UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Exiguobacterium sibiricum 255-15
Length = 274
Score = 73.3 bits (172), Expect = 5e-12
Identities = 36/83 (43%), Positives = 50/83 (60%)
Frame = +3
Query: 273 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH 452
+++ + REDIF+TTK+WN A SL+KLG+DY+DLYL+HWP+
Sbjct: 58 LKDSGIPREDIFLTTKVWNKDQGYERTLAAFETSLQKLGVDYVDLYLIHWPM------PD 111
Query: 453 SDVDFMETWRGLEDAQRMG*LKA 521
D+ +M+TWR LE R G KA
Sbjct: 112 EDL-YMDTWRALEQLYRDGKAKA 133
Score = 42.3 bits (95), Expect = 0.011
Identities = 21/60 (35%), Positives = 33/60 (55%)
Frame = +1
Query: 79 MNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
+NNG MP +G G + K ++++ + V A+ VGYR DTA +YE E +G+
Sbjct: 6 LNNGLVMPQLGYGVF---------KVPEQEVYEAVREALRVGYRSIDTAMIYENEAGVGR 56
Score = 39.1 bits (87), Expect = 0.10
Identities = 19/36 (52%), Positives = 24/36 (66%)
Frame = +2
Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
+G K IG+SNF+ L RVL+EGT+ P QIE H
Sbjct: 128 DGKAKAIGVSNFHIPHLTRVLEEGTVVPAVNQIELH 163
>UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep:
Aldehyde reductase - gamma proteobacterium HTCC2207
Length = 330
Score = 73.3 bits (172), Expect = 5e-12
Identities = 32/60 (53%), Positives = 41/60 (68%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
E + + EG+ RE+++ITTKLWNT HR V A S+ LGLDYIDLYL+H+PI L
Sbjct: 61 EGIARAIAEGLCSREELWITTKLWNTYHRAEHVEAACRRSMDDLGLDYIDLYLVHFPIAL 120
Score = 43.6 bits (98), Expect = 0.005
Identities = 24/70 (34%), Positives = 39/70 (55%)
Frame = +1
Query: 49 ASTMEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTAS 228
+ ++VP +K+++ + MPA+GLG + K V AI VGYRH D+A+
Sbjct: 2 SDAIQVPGVKVSS-KSMPAVGLGLW---------KITQDSAAQAVYEAIKVGYRHLDSAA 51
Query: 229 VYETEQEIGK 258
Y EQ++G+
Sbjct: 52 DYGNEQQVGE 61
>UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 320
Score = 73.3 bits (172), Expect = 5e-12
Identities = 39/82 (47%), Positives = 50/82 (60%), Gaps = 1/82 (1%)
Frame = +3
Query: 279 EGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYS-HS 455
EG++KREDIFITTK + + V +A+ +SLK+L LDY+DLYL H P D S S
Sbjct: 68 EGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAHIPASTKDDGSFRS 127
Query: 456 DVDFMETWRGLEDAQRMG*LKA 521
DV + WRG E +G KA
Sbjct: 128 DVKVEDIWRGFEKVYGLGLTKA 149
Score = 49.2 bits (112), Expect = 1e-04
Identities = 25/65 (38%), Positives = 38/65 (58%)
Frame = +1
Query: 61 EVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240
+VP ++NG MP+IGLGT+ + G + V+ A+ GYRH DTA++Y+
Sbjct: 4 KVPIFTLSNGVLMPSIGLGTWQMTGEEG---------KTVIRNAVLAGYRHIDTATLYQN 54
Query: 241 EQEIG 255
E +IG
Sbjct: 55 EHQIG 59
Score = 34.7 bits (76), Expect = 2.3
Identities = 15/36 (41%), Positives = 23/36 (63%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGHL 613
G+ K IG+SNFN+ Q+ R++ + A Q+E HL
Sbjct: 145 GLTKAIGVSNFNESQIVRIMNIQKVPIHASQLELHL 180
>UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase
2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent
oxidoreductase 2 - Oryza sativa subsp. japonica (Rice)
Length = 322
Score = 73.3 bits (172), Expect = 5e-12
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 10/160 (6%)
Frame = +3
Query: 255 EAVKMKVEEGVV-KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431
EAV V G+V R D+F+T+KLW + V A ++L+ LG+DY+DL L+HWP
Sbjct: 65 EAVAEAVRRGLVASRADVFVTSKLWCSDLHAGRVVPAARETLRNLGMDYVDLLLVHWPAT 124
Query: 432 L---NADYSHSD------VDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSN 584
+ + D+ D WRG+E+ R+G +A ++ A+
Sbjct: 125 VAPGSYDFPFPKEEMAPAFDMEGVWRGMEECHRLGLARAIGVSNFSAKKLEQLLSFAVVR 184
Query: 585 LMLFK*RVTSKTFQKEMVEFCQSESVVVMGYSPFRFPGXP 704
+ + Q+ + E C+ E V + GYSP G P
Sbjct: 185 PAANQVEMNPMWQQRTLREVCRREGVQLCGYSPLGAKGTP 224
Score = 39.1 bits (87), Expect = 0.10
Identities = 20/49 (40%), Positives = 29/49 (59%)
Frame = +1
Query: 97 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243
MP IG+GT + ++ ++RAI++GYRHFDTA +Y TE
Sbjct: 18 MPRIGMGTA------AFPFTSSEETTAALLRAIELGYRHFDTARLYATE 60
>UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep:
Aldehyde reductase - Acidobacteria bacterium (strain
Ellin345)
Length = 313
Score = 72.9 bits (171), Expect = 7e-12
Identities = 47/155 (30%), Positives = 72/155 (46%), Gaps = 12/155 (7%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
EA++ G + RE+IF+TTKLWNT HR V A SL +LGLDY+DLYL+H P
Sbjct: 64 EALRAGRAAGNIAREEIFVTTKLWNTNHRPERVEPAFEASLDRLGLDYLDLYLIHTPFAF 123
Query: 435 -----------NADYSHSD-VDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKAL 578
N + + V ETW LE+ G +A + + A
Sbjct: 124 QPGDEQDPRDQNGSVIYDEGVTLRETWSALENLVDRGRCRAIGLSDISMDRLAPIYEAAR 183
Query: 579 SNLMLFK*RVTSKTFQKEMVEFCQSESVVVMGYSP 683
+ + + E++EFC+ +V++ ++P
Sbjct: 184 IKPAVVQVESHPYLPETELLEFCKRNGIVLLAFAP 218
Score = 33.1 bits (72), Expect = 6.9
Identities = 17/54 (31%), Positives = 28/54 (51%)
Frame = +1
Query: 97 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
+PA+G GT + + ++D A+ G+RHFD A Y E+E+G+
Sbjct: 20 IPALGFGTLIADPALTITATRD---------ALAAGFRHFDCAERYRNEREVGE 64
>UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 287
Score = 72.9 bits (171), Expect = 7e-12
Identities = 48/145 (33%), Positives = 71/145 (48%), Gaps = 3/145 (2%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP---I 428
A+ V E + RED F+T+KLW T+ +A + +L++LG DY+DLYL+HWP +
Sbjct: 56 ALGQAVAESDIPREDFFLTSKLWKTEMGYDAALRAFDATLERLGTDYLDLYLIHWPRPDL 115
Query: 429 GLNADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RV 608
L D++ D ETWR LE G ++A A M+ +
Sbjct: 116 ELE-DWAKLD---RETWRALERLYESGLVRAIGVSNFLPHHLEPILASANVAPMVDQLEF 171
Query: 609 TSKTFQKEMVEFCQSESVVVMGYSP 683
Q E V FCQ+ S++V +SP
Sbjct: 172 HPGYTQDEAVAFCQNHSILVEAWSP 196
Score = 45.2 bits (102), Expect = 0.002
Identities = 26/60 (43%), Positives = 33/60 (55%)
Frame = +1
Query: 79 MNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
++NG +PA+G GTY D + V S AI GYRHFDTAS Y TE +G+
Sbjct: 10 LSNGLSIPAVGFGTYKTGDGDSAVLSN----------AIAQGYRHFDTASFYGTETALGQ 59
Score = 33.1 bits (72), Expect = 6.9
Identities = 15/40 (37%), Positives = 22/40 (55%)
Frame = +2
Query: 491 RCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
R +G+V+ IG+SNF LE +L + P Q+E H
Sbjct: 133 RLYESGLVRAIGVSNFLPHHLEPILASANVAPMVDQLEFH 172
>UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 263
Score = 72.5 bits (170), Expect = 9e-12
Identities = 44/134 (32%), Positives = 68/134 (50%), Gaps = 2/134 (1%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDF 467
V R+D+FITTK+WN R +V A SL +LGLDYIDLYL+HWP+ F
Sbjct: 53 VPRKDLFITTKIWNNAQRLGDVEGAFQRSLDRLGLDYIDLYLIHWPV---------PGCF 103
Query: 468 METWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTSK--TFQKEMVE 641
+ TW+ +E G +A S + +S ++ ++ + KE++E
Sbjct: 104 LNTWKDMEKILESG--RALSIGVSNFEIRHLEELRRVSGIVPAVNQIECHPLCYPKELIE 161
Query: 642 FCQSESVVVMGYSP 683
+CQ+ + V Y+P
Sbjct: 162 YCQANDIQVQAYAP 175
Score = 33.9 bits (74), Expect = 3.9
Identities = 19/53 (35%), Positives = 26/53 (49%)
Frame = +1
Query: 97 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
MP +GLG Y D + D + A+ GYR DTAS Y+ E+ +G
Sbjct: 1 MPLLGLGLYKTTDA--------VEAEDAIAAAVQNGYRLLDTASAYKNEEFVG 45
>UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep:
Benzil reductase - Bacillus subtilis
Length = 276
Score = 71.7 bits (168), Expect = 2e-11
Identities = 42/143 (29%), Positives = 70/143 (48%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
E V + ++E V RE++FIT+K+WN A SL++L LDY+DLYL+HWP
Sbjct: 58 EGVGIGIKESGVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWP--- 114
Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTS 614
+ +TWR LE + G ++A K A M+ +
Sbjct: 115 ------GKDKYKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQVEFHP 168
Query: 615 KTFQKEMVEFCQSESVVVMGYSP 683
+ QKE+ ++C+++ + + +SP
Sbjct: 169 RLTQKELRDYCKAQGIQLEAWSP 191
Score = 38.3 bits (85), Expect = 0.18
Identities = 22/62 (35%), Positives = 34/62 (54%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249
++K++NG MP GLG + + N +S V AI GYR DTA++Y+ E+
Sbjct: 8 TVKLHNGVEMPWFGLGVFKVENGNEATES--------VKAAIKNGYRSIDTAAIYKNEEG 59
Query: 250 IG 255
+G
Sbjct: 60 VG 61
>UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 337
Score = 71.7 bits (168), Expect = 2e-11
Identities = 32/82 (39%), Positives = 48/82 (58%), Gaps = 3/82 (3%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
EA++ E G KRED+F+T+KLWN + R +V +A+ +L LG+ Y+DLYL+HWP+
Sbjct: 60 EALREAFERGDAKREDVFVTSKLWNDRRRPRDVREALMTTLNDLGVGYLDLYLIHWPVAW 119
Query: 435 NAD---YSHSDVDFMETWRGLE 491
++ E W LE
Sbjct: 120 KRGTVLQPDAEASIAECWSELE 141
Score = 43.2 bits (97), Expect = 0.006
Identities = 21/58 (36%), Positives = 32/58 (55%)
Frame = +1
Query: 85 NGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
NG +P +GLGT+ K++ ++RD V A+ GY H D A+ Y E E+G+
Sbjct: 12 NGLRIPRVGLGTW---------KARPNEVRDAVRDALGAGYAHVDCAAAYANESEVGE 60
Score = 37.9 bits (84), Expect = 0.24
Identities = 19/46 (41%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Frame = +2
Query: 479 ARIGRCSANGIVKGIGLSNFNKQQLERVLKE--GTIKPDAIQIEGH 610
+ + RC A+G+V+ IG+SNFN+ QL + + I+P QIE H
Sbjct: 138 SELERCVADGLVRHIGVSNFNEAQLAALCDDPRTKIQPACNQIESH 183
>UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium
SCB49|Rep: ARA1 - unidentified eubacterium SCB49
Length = 280
Score = 71.3 bits (167), Expect = 2e-11
Identities = 37/143 (25%), Positives = 71/143 (49%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
+ V + ++E + R+D+F+T+K+WN Q +A ++++ L LDY+DLYL+HWP
Sbjct: 54 KGVGLGIKEANIDRKDLFVTSKVWNEQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAA 113
Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTS 614
+ + ++ +TW +E + G +KA + A + +
Sbjct: 114 HQFENWKQLN-NDTWSAMEKLYKDGKIKALGVSNFMEHHLTPLLQHATIKPTVNQIEYHP 172
Query: 615 KTFQKEMVEFCQSESVVVMGYSP 683
Q++ V+FC ++ V G+SP
Sbjct: 173 GYMQQDCVQFCNDNNIQVEGWSP 195
Score = 42.7 bits (96), Expect = 0.009
Identities = 21/60 (35%), Positives = 33/60 (55%)
Frame = +1
Query: 76 KMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
K+NN +PAIG GT+ D + + + AID GY+H D A++Y+ E+ +G
Sbjct: 6 KLNNNINIPAIGFGTWQTPDGQTAINA--------IKTAIDAGYKHIDAAAIYKNEKGVG 57
>UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase;
n=2; Parasitella parasitica|Rep:
4-dihydromethyltrisporate dehydrogenase - Parasitella
parasitica
Length = 321
Score = 71.3 bits (167), Expect = 2e-11
Identities = 33/73 (45%), Positives = 45/73 (61%)
Frame = +3
Query: 261 VKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA 440
+ ++EG+VKRE++FI TKLWNT H + V A + LK GL+Y DLYL+H+PI L
Sbjct: 61 INKAIKEGLVKREELFIVTKLWNTFHSKQHVRTAFDRQLKDWGLEYFDLYLIHFPIPL-- 118
Query: 441 DYSHSDVDFMETW 479
Y V + W
Sbjct: 119 QYVDPAVSYPPEW 131
Score = 33.1 bits (72), Expect = 6.9
Identities = 15/39 (38%), Positives = 22/39 (56%)
Frame = +1
Query: 142 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
G K + K + + +AI +GYR FD A Y E E+G+
Sbjct: 21 GCWKIEKKDAENTIYQAIKIGYRLFDGACDYGNEVEVGR 59
>UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 345
Score = 71.3 bits (167), Expect = 2e-11
Identities = 43/145 (29%), Positives = 67/145 (46%), Gaps = 13/145 (8%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH----- 452
V RE+IF+T+KLWNT H V +A++ SL L DY+DLYL+HWP+ +
Sbjct: 66 VPREEIFLTSKLWNTHHHPENVEEAVDKSLADLQTDYLDLYLIHWPVAFRYSTTTIQPVN 125
Query: 453 --------SDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RV 608
DV +TW +E G +++ T K A + +
Sbjct: 126 EQTGLIDVVDVPIKDTWAAMEKLVEKGKVRSIGVSNFTREKIEELLKTAKITPAVNQIEA 185
Query: 609 TSKTFQKEMVEFCQSESVVVMGYSP 683
Q++++E+ + +VV GYSP
Sbjct: 186 HPFLQQRDLLEWSTQKGIVVAGYSP 210
Score = 57.2 bits (132), Expect = 4e-07
Identities = 28/62 (45%), Positives = 39/62 (62%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249
+ K+N G MPA+GLGT+ +SK ++RD V+ A+ GYRH D A+VY EQE
Sbjct: 6 TFKLNTGYDMPAVGLGTW---------QSKKDEVRDAVIAALKCGYRHIDAAAVYGNEQE 56
Query: 250 IG 255
+G
Sbjct: 57 VG 58
Score = 37.5 bits (83), Expect = 0.32
Identities = 16/35 (45%), Positives = 23/35 (65%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
G V+ IG+SNF ++++E +LK I P QIE H
Sbjct: 152 GKVRSIGVSNFTREKIEELLKTAKITPAVNQIEAH 186
>UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=3; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 324
Score = 70.9 bits (166), Expect = 3e-11
Identities = 30/63 (47%), Positives = 48/63 (76%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
+ +K ++E +VKRE++F+TTK+W T + R V+++++ SLK L LDY+DL L+HWP+ L
Sbjct: 57 KGIKRAIDEELVKRENLFVTTKVWPTFYNR--VSESLDISLKDLSLDYVDLLLVHWPVSL 114
Query: 435 NAD 443
AD
Sbjct: 115 LAD 117
Score = 49.2 bits (112), Expect = 1e-04
Identities = 26/63 (41%), Positives = 37/63 (58%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249
S K+N+G +PA+GLGT + D + +VV AI GYRH DTA +Y +E +
Sbjct: 6 SFKLNDGHSIPALGLGT-----------ASDGNVEEVVYAAIKNGYRHIDTAFIYGSEVD 54
Query: 250 IGK 258
+GK
Sbjct: 55 VGK 57
>UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase A - Corynebacterium sp. (strain ATCC 31090)
Length = 278
Score = 70.9 bits (166), Expect = 3e-11
Identities = 32/67 (47%), Positives = 42/67 (62%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
E V + + R+D+FITTKLWN +H E A AI +SL KL LD +DLYL+HWP
Sbjct: 54 EGVGAAIAASGIARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWPTPA 113
Query: 435 NADYSHS 455
+Y H+
Sbjct: 114 ADNYVHA 120
Score = 46.4 bits (105), Expect = 7e-04
Identities = 25/66 (37%), Positives = 37/66 (56%)
Frame = +1
Query: 58 MEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237
M VPS+ +N+G +P +G G + V D Q V A++VGYRH DTA++Y
Sbjct: 1 MTVPSIVLNDGNSIPQLGYGVFK-------VPPADTQR--AVEEALEVGYRHIDTAAIYG 51
Query: 238 TEQEIG 255
E+ +G
Sbjct: 52 NEEGVG 57
>UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy
chain; n=3; Saccharomycetaceae|Rep: D-arabinose
dehydrogenase [NAD(P)+] heavy chain - Saccharomyces
cerevisiae (Baker's yeast)
Length = 344
Score = 70.9 bits (166), Expect = 3e-11
Identities = 31/58 (53%), Positives = 44/58 (75%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428
EA+K +E+G +KRED+FITTK+W EV +++N+SLK LGL+Y+DL L HWP+
Sbjct: 79 EAIKELLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPL 134
Score = 44.4 bits (100), Expect = 0.003
Identities = 25/60 (41%), Positives = 32/60 (53%)
Frame = +1
Query: 79 MNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
+NNG +PA+GLGT K + + V AI GYRH DTA YETE +G+
Sbjct: 27 LNNGVRIPALGLGT-------ANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGE 79
Score = 38.3 bits (85), Expect = 0.18
Identities = 16/33 (48%), Positives = 24/33 (72%)
Frame = +2
Query: 512 VKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
V+ IG+SNF+ + LER++KE +KP Q+E H
Sbjct: 186 VRAIGVSNFSIEYLERLIKECRVKPTVNQVETH 218
>UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:
Aldehyde reductase - Salinibacter ruber (strain DSM
13855)
Length = 321
Score = 70.5 bits (165), Expect = 4e-11
Identities = 42/160 (26%), Positives = 76/160 (47%), Gaps = 10/160 (6%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL- 434
A+ + G ++R+D+++T+KLWN H +V A+ +L L LD +DLYL+HWP+ L
Sbjct: 57 ALSDSFDAGGIRRDDVWVTSKLWNNAHHPDDVRPALEQTLSDLRLDALDLYLIHWPVALQ 116
Query: 435 -NADYSHSDVDFM--------ETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNL 587
D+ S DF+ ETW +E ++ G ++ + + +
Sbjct: 117 PEVDFPESPDDFVSPEAVPLTETWAAMEALKKDGLVRHIGVSNFSVPNLQMILDAGEVRP 176
Query: 588 MLFK*RVTSKTFQKEMVEFCQSESVVVMGYSPFRFPGXPD 707
+ + + Q E+V F ++ ++ + YSP PD
Sbjct: 177 EMNQVEMHPYLPQPELVSFAEAHNIPITAYSPLGSGDRPD 216
Score = 46.8 bits (106), Expect = 5e-04
Identities = 24/62 (38%), Positives = 34/62 (54%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249
S+ NG MP IGLGT+ KS ++ + V A++ GYRH D A +Y+ E E
Sbjct: 3 SISFENGDEMPMIGLGTW---------KSPPGEVYEAVTTALEAGYRHVDCAPIYKNETE 53
Query: 250 IG 255
+G
Sbjct: 54 VG 55
Score = 36.7 bits (81), Expect = 0.56
Identities = 14/36 (38%), Positives = 25/36 (69%)
Frame = +2
Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
+G+V+ IG+SNF+ L+ +L G ++P+ Q+E H
Sbjct: 149 DGLVRHIGVSNFSVPNLQMILDAGEVRPEMNQVEMH 184
>UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate
dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent
D-sorbitol-6-phosphate dehydrogenase - Malus domestica
(Apple) (Malus sylvestris)
Length = 310
Score = 70.5 bits (165), Expect = 4e-11
Identities = 50/161 (31%), Positives = 80/161 (49%), Gaps = 18/161 (11%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP--- 425
EA+ + G+VKRE++FITTK+WN+ H V +A +SL+KL +DY+DLYL+H+P
Sbjct: 56 EALAEAFKTGLVKREELFITTKIWNSDH--GHVVEACKNSLEKLQIDYLDLYLVHYPMPT 113
Query: 426 ----IGLNADYSHSD--------VDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC-- 563
IG A D + +TW G+E +G +++ R C
Sbjct: 114 KHNAIGKTASLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSNYELFLTRDCLA 173
Query: 564 *KKALSNLMLFK*RVTSKTFQKE-MVEFCQSESVVVMGYSP 683
K + F+ T FQ++ +V+FC V+ ++P
Sbjct: 174 YSKIKPAVSQFE---THPYFQRDSLVKFCMKHGVLPTAHTP 211
Score = 46.8 bits (106), Expect = 5e-04
Identities = 21/63 (33%), Positives = 41/63 (65%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249
++ +++G MP IGLG + + + +L++V++ AI +GYRHFD A+ Y++E +
Sbjct: 3 TVTLSSGYEMPVIGLGLW---------RLEKDELKEVILNAIKIGYRHFDCAAHYKSEAD 53
Query: 250 IGK 258
+G+
Sbjct: 54 VGE 56
>UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 323
Score = 70.1 bits (164), Expect = 5e-11
Identities = 47/159 (29%), Positives = 75/159 (47%), Gaps = 11/159 (6%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI-- 428
EA+ + EG VKRE++F+T+KLW H +V A +LK L LDY+DLYL+H P+
Sbjct: 60 EALSEVLTEGKVKREELFVTSKLWCDSHHPDDVLPACQATLKNLQLDYLDLYLIHIPVAF 119
Query: 429 --GLNADYS-------HSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALS 581
G+ +S ++ TW+ +E G KA + + A
Sbjct: 120 KKGVRLPHSIAEGIIGYTPEGVQNTWQAMEGLVAKGLCKAIGVSNFSVKRLNKLLETASI 179
Query: 582 NLMLFK*RVTSKTFQKEMVEFCQSESVVVMGYSPFRFPG 698
+ + Q+++ EFC S+ +++ YSP PG
Sbjct: 180 VPACNQVELHPYLPQEKLKEFCDSKGILLTAYSPLGNPG 218
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/61 (37%), Positives = 36/61 (59%)
Frame = +1
Query: 76 KMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
K+N G +PA+ LGT+ +S +++ + V AI++GYRH D A +Y E EIG
Sbjct: 9 KLNTGASIPAMALGTW---------QSSKEEVGNAVRLAIELGYRHIDCAEIYGNEGEIG 59
Query: 256 K 258
+
Sbjct: 60 E 60
Score = 35.1 bits (77), Expect = 1.7
Identities = 15/37 (40%), Positives = 25/37 (67%)
Frame = +2
Query: 500 ANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
A G+ K IG+SNF+ ++L ++L+ +I P Q+E H
Sbjct: 153 AKGLCKAIGVSNFSVKRLNKLLETASIVPACNQVELH 189
>UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several
dehydrogenases of different specificities; n=4;
Pezizomycotina|Rep: Similarity: shows similarity to
several dehydrogenases of different specificities -
Aspergillus niger
Length = 381
Score = 70.1 bits (164), Expect = 5e-11
Identities = 28/47 (59%), Positives = 39/47 (82%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428
+KREDIFIT+KLWN+QH V +A+++ L +L LDY+DLYL+HWP+
Sbjct: 71 LKREDIFITSKLWNSQHDPAVVEKALDECLAELELDYLDLYLVHWPV 117
Score = 41.5 bits (93), Expect = 0.020
Identities = 19/60 (31%), Positives = 34/60 (56%)
Frame = +1
Query: 79 MNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
+N+G +P +G GT+ +S Q+ D V A+ GYRH D A++Y+ ++E+ +
Sbjct: 9 LNSGAQIPQLGFGTW---------QSAPGQVGDAVYEALKAGYRHLDLATIYQNQREVAE 59
>UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=3; Lactobacillales|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 292
Score = 69.7 bits (163), Expect = 6e-11
Identities = 35/89 (39%), Positives = 50/89 (56%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
EA+ + +G+VKRE++F+T+K+W + AI SL++L LDY+DLYL+H P
Sbjct: 57 EAILEAINQGIVKREELFVTSKMWVQDVSAQQATAAIQSSLQRLNLDYLDLYLIHQPYN- 115
Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKA 521
D WR +E A R G LKA
Sbjct: 116 ---------DVFGAWRAMESAYRSGQLKA 135
Score = 33.5 bits (73), Expect = 5.2
Identities = 20/58 (34%), Positives = 29/58 (50%)
Frame = +1
Query: 85 NGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
+G MP +G G + + G K V+ AI GYR DTA+ Y E+E+G+
Sbjct: 8 SGIEMPLLGFGVFQ-VQEKGAAKQ-------AVLDAIKTGYRLIDTAASYGNEREVGE 57
>UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG03517.1 - Gibberella zeae PH-1
Length = 364
Score = 69.3 bits (162), Expect = 9e-11
Identities = 30/76 (39%), Positives = 48/76 (63%), Gaps = 2/76 (2%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSD--V 461
V R++I++T KLWNT HR V +AI S+ LG++Y+DLYL+H+P+ + D
Sbjct: 111 VSRDEIWVTGKLWNTDHRPELVRKAIETSIANLGVEYLDLYLIHYPVAWVPETRDVDNNT 170
Query: 462 DFMETWRGLEDAQRMG 509
++TW+ +E+ R G
Sbjct: 171 SLIDTWKAMEELVRAG 186
Score = 40.7 bits (91), Expect = 0.034
Identities = 27/67 (40%), Positives = 34/67 (50%), Gaps = 1/67 (1%)
Frame = +1
Query: 61 EVPSLKMNNG-RXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237
E+P N R +PA GLGT+L GVV V A+ GYRH DTA ++
Sbjct: 47 EMPEFNKNETVRDIPAFGLGTWLA--GKGVVVP-------AVEYALKGGYRHIDTALIWR 97
Query: 238 TEQEIGK 258
E E+GK
Sbjct: 98 NEDEVGK 104
Score = 32.7 bits (71), Expect = 9.1
Identities = 13/35 (37%), Positives = 22/35 (62%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
G+ + IG SNF + + ++LK +I+P A + E H
Sbjct: 186 GLTRNIGFSNFAPKDINKILKIASIQPYAHEFETH 220
>UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=10; Trichomonas vaginalis|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 312
Score = 69.3 bits (162), Expect = 9e-11
Identities = 44/166 (26%), Positives = 81/166 (48%), Gaps = 19/166 (11%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
E +K +G +KRED+FITTKLW T HR+ V ++++L +L L Y+DL+L+H PI
Sbjct: 49 ETLKEIFAKGKIKREDMFITTKLWCTHHRKDLVEPELHENLAQLQLSYVDLFLIHQPIAF 108
Query: 435 NA---------------DYSHSDVDFMETWRGLEDAQRMG*LK----ASDCLTSTSSSWR 557
+ + +D +ET+ +E+ Q+ G + ++ + W
Sbjct: 109 KSLPAKDGTMMPKDEKGKIQYEQIDILETYHAMEECQKKGLTRHIGVSNFSIEQLERIWF 168
Query: 558 GC*KKALSNLMLFK*RVTSKTFQKEMVEFCQSESVVVMGYSPFRFP 695
C K +N + + F K ++ +C+S ++ +M ++ P
Sbjct: 169 NCEIKPYANQVECN---IYRQF-KPLLSYCESHNIYLMAHTTIGHP 210
Score = 37.9 bits (84), Expect = 0.24
Identities = 23/62 (37%), Positives = 35/62 (56%)
Frame = +2
Query: 494 CSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGHLQNVSERNGGILSV*KCCSHG 673
C G+ + IG+SNF+ +QLER+ IKP A Q+E N+ + +LS C SH
Sbjct: 144 CQKKGLTRHIGVSNFSIEQLERIWFNCEIKPYANQVE---CNIYRQFKPLLSY--CESHN 198
Query: 674 LF 679
++
Sbjct: 199 IY 200
>UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 293
Score = 68.9 bits (161), Expect = 1e-10
Identities = 32/82 (39%), Positives = 48/82 (58%)
Frame = +3
Query: 273 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH 452
+ E V R+ IF+T+KLWN+ E A ++L KLGLDY+DLYL+HWP
Sbjct: 69 IRESDVPRDQIFVTSKLWNSVRGYDETQAAFQETLDKLGLDYLDLYLIHWPA-------- 120
Query: 453 SDVDFMETWRGLEDAQRMG*LK 518
++++WR +ED + G +K
Sbjct: 121 --PGYLDSWRAMEDLYKAGKIK 140
Score = 46.8 bits (106), Expect = 5e-04
Identities = 24/66 (36%), Positives = 38/66 (57%)
Frame = +1
Query: 61 EVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240
++P L MNNG +P +GLG + V ++D ++ + A+ GYRH DTA+ Y
Sbjct: 10 DIPDLPMNNGHQIPQLGLGVFQ------VDNAEDT--KNAIKWALAAGYRHIDTAAYYGN 61
Query: 241 EQEIGK 258
EQ +G+
Sbjct: 62 EQWVGE 67
Score = 41.9 bits (94), Expect = 0.015
Identities = 18/35 (51%), Positives = 24/35 (68%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
G +K IG+SNFN+ Q+ +L GT+KP QIE H
Sbjct: 137 GKIKNIGVSNFNQTQMADILAHGTVKPVVDQIETH 171
>UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde
reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep:
NADH/NADPH dependent indole-3-acetaldehyde reductase
AKR3C2 - Schizosaccharomyces pombe (Fission yeast)
Length = 284
Score = 68.9 bits (161), Expect = 1e-10
Identities = 43/145 (29%), Positives = 72/145 (49%), Gaps = 2/145 (1%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
E V + ++E V R +FIT+K+ H + +A+N+SL+KLG DY+DLYL+H PI
Sbjct: 58 EEVGVALKEANVPRSKLFITSKV---MHNVDNIPEALNESLRKLGTDYLDLYLLHSPI-- 112
Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTS 614
+ + E W+ +E A G + + K + + +
Sbjct: 113 --PFYEKKIPISEGWKAMETALGTGLVHSVGVSNFRIPDLEELLKTSTITPRVNQIEFHP 170
Query: 615 KTFQ--KEMVEFCQSESVVVMGYSP 683
+ ++ K +VEFCQS+ ++V GY P
Sbjct: 171 QVYKAAKPLVEFCQSKGIIVEGYGP 195
Score = 37.5 bits (83), Expect = 0.32
Identities = 19/53 (35%), Positives = 30/53 (56%)
Frame = +1
Query: 97 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
+PA G+GT L + G + ++ + D V A+ G+ H D A VY E+E+G
Sbjct: 12 VPAYGVGTALFKKEKGEI---NRTIVDSVKNALAAGFIHIDCAEVYGNEEEVG 61
Score = 37.1 bits (82), Expect = 0.42
Identities = 18/37 (48%), Positives = 22/37 (59%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGHLQ 616
G+V +G+SNF LE +LK TI P QIE H Q
Sbjct: 135 GLVHSVGVSNFRIPDLEELLKTSTITPRVNQIEFHPQ 171
>UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon
cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon
cuniculi
Length = 301
Score = 68.5 bits (160), Expect = 1e-10
Identities = 48/155 (30%), Positives = 76/155 (49%), Gaps = 15/155 (9%)
Frame = +3
Query: 261 VKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI---- 428
+K +EGVV+R+D+FIT+KLWNT H E + SL L +DY+DLYL+HWP+
Sbjct: 61 LKKLFDEGVVQRKDLFITSKLWNTFHGCPE--DGLRRSLNDLQMDYVDLYLIHWPVTFDP 118
Query: 429 -------GLNADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNL 587
Y+ D + W+ +E +G K+ S+ + +K L
Sbjct: 119 APDGTVESCGKKYNVGKFDAVGVWKKMEALVDLGLAKS----IGISNFGKANTEKILGTC 174
Query: 588 MLFK*RVTSKTF----QKEMVEFCQSESVVVMGYS 680
+ + + QKE+VEF +S+ + V+ YS
Sbjct: 175 RICPAAIQIELHPYLNQKELVEFMKSKGIQVISYS 209
Score = 48.8 bits (111), Expect = 1e-04
Identities = 24/60 (40%), Positives = 35/60 (58%)
Frame = +1
Query: 76 KMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
K+NNG+ +P +GLGT+ G + V L + A+ +GYRH DTA +Y E+ IG
Sbjct: 7 KLNNGKEIPTVGLGTW-GMEDEAV-------LEGAIRNALSLGYRHIDTAFIYGNEKMIG 58
Score = 37.5 bits (83), Expect = 0.32
Identities = 18/35 (51%), Positives = 22/35 (62%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
G+ K IG+SNF K E++L I P AIQIE H
Sbjct: 152 GLAKSIGISNFGKANTEKILGTCRICPAAIQIELH 186
>UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 286
Score = 68.1 bits (159), Expect = 2e-10
Identities = 29/58 (50%), Positives = 41/58 (70%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431
A+K ++EG+V+RE++F+TTKLW + +A SLKKL L+YIDLYL+H P G
Sbjct: 59 AIKRAIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQPFG 116
Score = 43.2 bits (97), Expect = 0.006
Identities = 23/67 (34%), Positives = 36/67 (53%)
Frame = +1
Query: 58 MEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237
M+VP + +NNG MP +G G + + ++ + V AI VGYR DTA+ Y
Sbjct: 1 MQVPKVTLNNGVEMPILGYGVF---------QIPPEKTEECVYEAIKVGYRLIDTAASYM 51
Query: 238 TEQEIGK 258
E+ +G+
Sbjct: 52 NEEGVGR 58
>UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep:
AkrI - Butyrivibrio fibrisolvens
Length = 172
Score = 68.1 bits (159), Expect = 2e-10
Identities = 30/88 (34%), Positives = 51/88 (57%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437
A+K +EE KREDIF+T+K W T+ + A ++ ++ +DY+DLYL+HWP
Sbjct: 62 AIKDFMEESQTKREDIFVTSKAWKTELGYDKTLAAFEKTMNEMQMDYLDLYLVHWPASYA 121
Query: 438 ADYSHSDVDFMETWRGLEDAQRMG*LKA 521
D + + +TW+ + + + G +KA
Sbjct: 122 FDDDWENTN-RQTWKAMTEIYKSGRVKA 148
Score = 44.8 bits (101), Expect = 0.002
Identities = 25/58 (43%), Positives = 31/58 (53%)
Frame = +1
Query: 73 LKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 246
+K+NNG +P G GTY DQN S V A+ GYRH DTA+ YE E+
Sbjct: 8 IKLNNGTAIPMFGYGTYKIKDQNEAYNS--------VRLALKNGYRHIDTAAFYENEK 57
>UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2;
Ascomycota|Rep: Aldo/keto reductase family proteins -
Aspergillus oryzae
Length = 323
Score = 68.1 bits (159), Expect = 2e-10
Identities = 27/47 (57%), Positives = 35/47 (74%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428
V R+ IFIT+KLWNT H V +A+N +LK L DY+DLYL+HWP+
Sbjct: 66 VPRDQIFITSKLWNTHHHPEHVEEAVNKTLKDLQTDYLDLYLIHWPV 112
Score = 50.0 bits (114), Expect = 6e-05
Identities = 25/62 (40%), Positives = 37/62 (59%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249
+ K+N+G +PAIGLGT+L SK ++ + V A+ GYRH D A+ Y+ E E
Sbjct: 6 TFKLNSGYNIPAIGLGTWL---------SKPHEVENAVEAALRAGYRHIDAAACYQNENE 56
Query: 250 IG 255
+G
Sbjct: 57 VG 58
Score = 33.1 bits (72), Expect = 6.9
Identities = 13/33 (39%), Positives = 21/33 (63%)
Frame = +2
Query: 512 VKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
++ IG+SNF + +++ +LK I P QIE H
Sbjct: 154 IRSIGISNFTQDKIDDLLKTAKIPPAVNQIEAH 186
>UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Escherichia coli (strain UTI89 / UPEC)
Length = 294
Score = 67.7 bits (158), Expect = 3e-10
Identities = 39/90 (43%), Positives = 51/90 (56%), Gaps = 1/90 (1%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQA-INDSLKKLGLDYIDLYLMHWPIG 431
EAV+ + EG+ RE++FIT+KLW ++A A I SLKK GL+Y DLYL+H +
Sbjct: 62 EAVREAISEGLCTREELFITSKLWVQDMLNQDIAAAGIEASLKKSGLEYFDLYLLHQAMR 121
Query: 432 LNADYSHSDVDFMETWRGLEDAQRMG*LKA 521
D+ WR LEDA G LKA
Sbjct: 122 ----------DYFSAWRALEDAYEEGKLKA 141
Score = 33.9 bits (74), Expect = 3.9
Identities = 17/40 (42%), Positives = 24/40 (60%), Gaps = 1/40 (2%)
Frame = +1
Query: 142 GVVKSKDKQL-RDVVMRAIDVGYRHFDTASVYETEQEIGK 258
GV + DK + + V+ AI GYR DTA+VY E +G+
Sbjct: 23 GVFQVTDKDVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGE 62
>UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7;
cellular organisms|Rep: Prostaglandin f synthase,
putative - Leishmania major
Length = 279
Score = 67.7 bits (158), Expect = 3e-10
Identities = 36/89 (40%), Positives = 47/89 (52%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
+ V + E V R DIF+TTKLWN H A S + LG++Y+DLYL+HWP G
Sbjct: 56 KGVGQGISECGVPRSDIFVTTKLWNYDHGYESALAAFEQSRQALGVEYVDLYLIHWP-GP 114
Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKA 521
N Y +ETWR E M ++A
Sbjct: 115 NRSY-------IETWRAFEKLYEMKKVRA 136
Score = 41.1 bits (92), Expect = 0.026
Identities = 22/60 (36%), Positives = 34/60 (56%)
Frame = +1
Query: 79 MNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
++NG +P +G+GT+ D N VV K A++ GYRH DTA Y+ E+ +G+
Sbjct: 10 LSNGVQVPQLGIGTWEAKDGNEVVNIK---------WAVNAGYRHVDTAHYYKNEKGVGQ 60
>UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3;
n=39; cellular organisms|Rep: NADPH-dependent aldose
reductase GRE3 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 327
Score = 67.7 bits (158), Expect = 3e-10
Identities = 50/169 (29%), Positives = 80/169 (47%), Gaps = 25/169 (14%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
E ++ + EG+V R+DIF+ +KLWN H V A+ +L +GLDY+DLY +H+PI
Sbjct: 57 EGIRKAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAF 116
Query: 435 ---------------NAD------YSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSS- 548
AD + + V ++T+R LE+ G +K+ S
Sbjct: 117 KYVPFEEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSL 176
Query: 549 ---SWRGC*KKALSNLMLFK*RVTSKTFQKEMVEFCQSESVVVMGYSPF 686
RGC K ++ + +T Q+ +VEFC+ + V+ YS F
Sbjct: 177 IQDLLRGCRIKPVALQIEHHPYLT----QEHLVEFCKLHDIQVVAYSSF 221
Score = 38.7 bits (86), Expect = 0.14
Identities = 17/39 (43%), Positives = 25/39 (64%)
Frame = +2
Query: 494 CSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
C G++K IG+SNF ++ +L+ IKP A+QIE H
Sbjct: 158 CVDEGLIKSIGVSNFQGSLIQDLLRGCRIKPVALQIEHH 196
Score = 37.5 bits (83), Expect = 0.32
Identities = 22/60 (36%), Positives = 31/60 (51%)
Frame = +1
Query: 79 MNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
+NNG MP +GLG + K K + + AI +GYR FD A Y E+E+G+
Sbjct: 7 LNNGLKMPLVGLGCW---------KIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGE 57
>UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1
protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo
sapiens "AKR1B1 protein. - Takifugu rubripes
Length = 330
Score = 67.3 bits (157), Expect = 3e-10
Identities = 29/57 (50%), Positives = 41/57 (71%)
Frame = +3
Query: 261 VKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431
V+ +++GVVKRE++FI +KLW T H + V A +L L LDY+DLYLMH+P+G
Sbjct: 59 VQAMIDQGVVKREELFIVSKLWCTFHTPSLVRGACEKTLSSLNLDYVDLYLMHFPMG 115
Score = 51.6 bits (118), Expect = 2e-05
Identities = 28/64 (43%), Positives = 35/64 (54%)
Frame = +1
Query: 64 VPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243
+PS+ +N G MP +GLGT+ KS + V AI GYRH DTA VYE E
Sbjct: 2 IPSVTLNTGALMPVLGLGTW---------KSGKGVTTEAVKVAIGAGYRHIDTAYVYENE 52
Query: 244 QEIG 255
E+G
Sbjct: 53 TEVG 56
Score = 37.9 bits (84), Expect = 0.24
Identities = 19/38 (50%), Positives = 25/38 (65%), Gaps = 2/38 (5%)
Frame = +2
Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTI--KPDAIQIEGH 610
+G+ K IG+SNFNK Q+E VL + + KP QIE H
Sbjct: 175 DGLAKAIGISNFNKDQIEAVLNKPGLKHKPATNQIECH 212
>UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 274
Score = 67.3 bits (157), Expect = 3e-10
Identities = 37/136 (27%), Positives = 70/136 (51%), Gaps = 3/136 (2%)
Frame = +3
Query: 291 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFM 470
+RED+FI +K+W T RR ++ +++ ++LK+L DY+DLYL+HWP + ++
Sbjct: 75 RREDLFIVSKVWPTHLRRDDLLRSLENTLKRLDTDYVDLYLIHWP--------NPEIPLE 126
Query: 471 ETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLML--FK*RVTSKTFQKE-MVE 641
ET + + R G ++ K+ ++ K + + +++ ++E
Sbjct: 127 ETLSAMAEGVRQGLIRYIGVSNFDRRLLEEAISKSQEPIVCDQVKYNIEDRDPERDGLLE 186
Query: 642 FCQSESVVVMGYSPFR 689
FCQ V ++ YSP R
Sbjct: 187 FCQKNGVTLVAYSPLR 202
Score = 42.3 bits (95), Expect = 0.011
Identities = 25/62 (40%), Positives = 38/62 (61%), Gaps = 5/62 (8%)
Frame = +1
Query: 88 GRXMPAIGLGTYL--GFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY---ETEQEI 252
G +PA+GLGT+ GF+ S+D+++ +++ AI +GY H DTA Y TE+ I
Sbjct: 10 GEEIPALGLGTWGIGGFETPDY--SRDEEMVELLKTAIKMGYTHIDTAEYYGGGHTEELI 67
Query: 253 GK 258
GK
Sbjct: 68 GK 69
>UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 288
Score = 67.3 bits (157), Expect = 3e-10
Identities = 43/161 (26%), Positives = 78/161 (48%), Gaps = 11/161 (6%)
Frame = +3
Query: 255 EAVKMKVEEGVV-KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431
+AV V G+V R++++IT+KLW V ++ +L+K+ ++Y+DLYL+H+P+
Sbjct: 61 DAVAEAVRAGLVASRDELYITSKLWVAHAHPGHVLPSLRRALRKMQMEYLDLYLIHFPVS 120
Query: 432 L-------NADYSHSDVDFME---TWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALS 581
+ + YS D+ M+ W+ +E+ QR+G KA + A
Sbjct: 121 MRLAEDPESMTYSKDDLVMMDMEGVWKEMEECQRLGLTKAIGVSNFSCKKLETLLSFATI 180
Query: 582 NLMLFK*RVTSKTFQKEMVEFCQSESVVVMGYSPFRFPGXP 704
+ + V Q ++ EFC+ + + + YSP G P
Sbjct: 181 SPAANQVEVHPYCRQNKLREFCKEKGIQLCAYSPLGGKGTP 221
Score = 58.0 bits (134), Expect = 2e-07
Identities = 28/64 (43%), Positives = 42/64 (65%)
Frame = +1
Query: 64 VPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243
+P +++G+ MP +G+GT F S ++DVV+RAI+ GYRHFDTA+VY+TE
Sbjct: 1 MPEAALSSGKPMPRVGMGT-ASFPLGATDPST---VKDVVLRAIEAGYRHFDTAAVYQTE 56
Query: 244 QEIG 255
+G
Sbjct: 57 AILG 60
>UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=3; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 309
Score = 67.3 bits (157), Expect = 3e-10
Identities = 33/98 (33%), Positives = 57/98 (58%), Gaps = 13/98 (13%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
EA+ +G VKRE+++IT+K+WNT+HR + + + +LK+L L+Y+DL L+HW
Sbjct: 50 EALSEIFAKGQVKREEVWITSKVWNTKHRPDLLVKDVKKTLKELKLEYLDLVLVHWACAF 109
Query: 435 NA----DYSHSD---------VDFMETWRGLEDAQRMG 509
+ +Y D +D +ETW+ +E+ +G
Sbjct: 110 QSREDDEYLPRDETGKIITENIDILETWKAMEECYNLG 147
Score = 34.7 bits (76), Expect = 2.3
Identities = 22/55 (40%), Positives = 31/55 (56%), Gaps = 1/55 (1%)
Frame = +1
Query: 97 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAI-DVGYRHFDTASVYETEQEIGK 258
+P+IGLGT+L D L+ V AI D GYRH D A+ Y+ ++ IG+
Sbjct: 4 IPSIGLGTFLAEDPAA--------LKAAVHSAIEDSGYRHVDCAAYYKNQEIIGE 50
Score = 33.5 bits (73), Expect = 5.2
Identities = 17/42 (40%), Positives = 26/42 (61%), Gaps = 2/42 (4%)
Frame = +2
Query: 494 CSANGIVKGIGLSNFNKQQLERVLKEGTIK--PDAIQIEGHL 613
C G+ K IG+SNF+ +QLER+ + +K P Q+E H+
Sbjct: 143 CYNLGLAKHIGVSNFSIEQLERMRYDPGVKIQPYCNQVESHM 184
>UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 355
Score = 67.3 bits (157), Expect = 3e-10
Identities = 50/154 (32%), Positives = 81/154 (52%), Gaps = 15/154 (9%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP----------IGLN 437
V R ++F+TTK+W T HR+ E +++SL++LGLDY+DL L+HWP I LN
Sbjct: 100 VPRSELFVTTKIWCTYHRQPEAC--LDESLQRLGLDYVDLLLVHWPVPLVKRGDEKIPLN 157
Query: 438 ADYSHS-DVDFM--ETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RV 608
D S + D D+ +TW +E G KA +++ S ++ A + ++ +V
Sbjct: 158 EDGSRAIDRDWSPEQTWELMEKLPATGKTKAIG-VSNWSIAFLDK-LLAKAKIVPAANQV 215
Query: 609 TSKTF--QKEMVEFCQSESVVVMGYSPFRFPGXP 704
F Q E+V++C + ++ YSP G P
Sbjct: 216 ELHPFLPQHELVKYCHDKGILPQAYSPLGSSGGP 249
>UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Photorhabdus luminescens subsp. laumondii
Length = 292
Score = 66.9 bits (156), Expect = 5e-10
Identities = 28/51 (54%), Positives = 39/51 (76%)
Frame = +3
Query: 273 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425
++E + REDIF+TTKLWN +H + A+ +SL+KL LDY+DLYL+HWP
Sbjct: 61 LQETDIPREDIFVTTKLWNDRH--LDARAALTESLEKLQLDYVDLYLIHWP 109
Score = 47.2 bits (107), Expect = 4e-04
Identities = 21/63 (33%), Positives = 38/63 (60%)
Frame = +1
Query: 67 PSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 246
P +++ +G MP +GLG++ S D+Q+ + + A+D+GYR DTA++Y E+
Sbjct: 5 PIIRLADGNHMPQLGLGSWA---------SDDQQIAETIHAALDIGYRAIDTAAIYNNEK 55
Query: 247 EIG 255
+G
Sbjct: 56 GVG 58
Score = 33.9 bits (74), Expect = 3.9
Identities = 13/35 (37%), Positives = 23/35 (65%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
G+++ IG+SNF + ++R++ E + P QIE H
Sbjct: 130 GLIRSIGVSNFQPEHIQRLINETGVHPVINQIELH 164
>UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 305
Score = 66.9 bits (156), Expect = 5e-10
Identities = 45/139 (32%), Positives = 72/139 (51%), Gaps = 9/139 (6%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP--IGLNADYSHSDV 461
+KRED+FIT+K + +A SLKKL LDY+D YL+HWP GL+ S + +
Sbjct: 86 IKREDLFITSKCSFMEQGYENALKAFESSLKKLQLDYLDCYLIHWPGVKGLDGSDSGNSI 145
Query: 462 DFMETWRGLE---DAQRMG*LKASDC----LTSTSSSWRGC*KKALSNLMLFK*RVTSKT 620
+TWR LE +++ + S+ LT SS K A++ +
Sbjct: 146 QRAQTWRALEKLYQDKKVRSIGVSNYTINHLTELLSSPNLQIKPAINQV-----EFHPLN 200
Query: 621 FQKEMVEFCQSESVVVMGY 677
FQK+++EFC++ +++ Y
Sbjct: 201 FQKDLLEFCKNNKIILESY 219
Score = 35.5 bits (78), Expect = 1.3
Identities = 18/54 (33%), Positives = 29/54 (53%)
Frame = +1
Query: 97 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
MP +G+GT+ K + +++ ++ GYR DTAS+Y E+ IGK
Sbjct: 27 MPMLGIGTF-----------KLNDIENIIKVGLENGYRRIDTASMYNNEERIGK 69
>UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 700
Score = 66.9 bits (156), Expect = 5e-10
Identities = 27/58 (46%), Positives = 41/58 (70%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428
+AV +++ V R +++T+KLWN+ H V +A++ SLK LG DY+DLYLMHWP+
Sbjct: 60 DAVAAGIKKAGVPRSQLWLTSKLWNSFHHPEHVEKALDASLKDLGTDYLDLYLMHWPV 117
Score = 34.3 bits (75), Expect = 3.0
Identities = 16/36 (44%), Positives = 24/36 (66%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGHL 613
G V+ IG+SNFN ++ V+ E +IKP Q+E +L
Sbjct: 161 GKVRNIGVSNFNIRRTSEVVDEASIKPVVNQVEVNL 196
Score = 33.9 bits (74), Expect = 3.9
Identities = 20/68 (29%), Positives = 28/68 (41%)
Frame = +1
Query: 49 ASTMEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTAS 228
+S + + NG +P +G GT+ K +Q V AI GYRH D A
Sbjct: 4 SSVRRSANFTLANGAQIPKLGFGTW---------KMSKEQATPAVAHAIKTGYRHIDCAW 54
Query: 229 VYETEQEI 252
Y E +
Sbjct: 55 AYRNEDAV 62
>UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 322
Score = 66.9 bits (156), Expect = 5e-10
Identities = 36/81 (44%), Positives = 50/81 (61%)
Frame = +3
Query: 276 EEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHS 455
+E V R +IFIT+KLW+ H + A AI DSLKKL +DY+D+YLMH P + A+
Sbjct: 79 KENNVPRSEIFITSKLWDADHDKA--AAAIEDSLKKLNVDYMDMYLMHSPGTMGAEKR-- 134
Query: 456 DVDFMETWRGLEDAQRMG*LK 518
+E W+ LE+A G +K
Sbjct: 135 ----LEAWKALEEAVDAGKIK 151
Score = 41.5 bits (93), Expect = 0.020
Identities = 20/62 (32%), Positives = 31/62 (50%)
Frame = +1
Query: 73 LKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252
+K+NNG+ +P + LG Y D + A D GYRH D+A+ Y E+ +
Sbjct: 19 IKLNNGQEIPQVALGVYKA--------PNDGSTENACKWAFDAGYRHIDSAARYMNEESV 70
Query: 253 GK 258
G+
Sbjct: 71 GR 72
Score = 35.5 bits (78), Expect = 1.3
Identities = 16/35 (45%), Positives = 23/35 (65%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
G +K IG+SNF+ ++L+ +L IKP QIE H
Sbjct: 148 GKIKTIGVSNFDVEELDHLLANCRIKPAVNQIESH 182
>UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA
- Apis mellifera
Length = 321
Score = 66.5 bits (155), Expect = 6e-10
Identities = 45/145 (31%), Positives = 69/145 (47%), Gaps = 13/145 (8%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN--ADYSH--- 452
+KR DIFI TKL +R +V + I SL+ L L+Y+DLYL+H PIG D H
Sbjct: 69 LKRSDIFIVTKLPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLIHVPIGFEKVGDILHPFD 128
Query: 453 --------SDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RV 608
+ + +E W +E + G KA S + K + + + +
Sbjct: 129 ENGHIRLDNSTNHVEIWAEMEKQVKCGRTKAIGLSNFNISQIKRILKNTKMKISMLQIEL 188
Query: 609 TSKTFQKEMVEFCQSESVVVMGYSP 683
QKE+V+FC+ E++ + YSP
Sbjct: 189 HVYFQQKELVKFCKQENIPITAYSP 213
Score = 51.2 bits (117), Expect = 2e-05
Identities = 26/66 (39%), Positives = 40/66 (60%)
Frame = +1
Query: 58 MEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237
ME ++ + NG MP IG GT+ ++++K+L D + A++ GYRH DTA+ YE
Sbjct: 1 MEKNTILLPNGELMPIIGFGTW---------QAQEKELEDALNIALEAGYRHIDTATSYE 51
Query: 238 TEQEIG 255
E+ IG
Sbjct: 52 NEKVIG 57
>UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 353
Score = 66.1 bits (154), Expect = 8e-10
Identities = 46/150 (30%), Positives = 70/150 (46%), Gaps = 14/150 (9%)
Frame = +3
Query: 291 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP-----------IGLN 437
KREDIF+T+KL + V + I SL+KLGL Y+D+YL+H P + N
Sbjct: 94 KREDIFVTSKLPYYDNHPESVEKYIKLSLEKLGLQYLDMYLIHAPFAVHHKEDSYELATN 153
Query: 438 ADYS---HSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RV 608
D S + D + W+ +E + G K+ + K+A + V
Sbjct: 154 EDGSVVLDTQTDPIAVWKEMEKQVKEGRTKSIGLSNFNETQITNILKEAKIKPSNLQVEV 213
Query: 609 TSKTFQKEMVEFCQSESVVVMGYSPFRFPG 698
+ QK ++EFCQ ++V GY+P PG
Sbjct: 214 HAYHQQKPLIEFCQKNGIIVTGYAPLGSPG 243
Score = 36.3 bits (80), Expect = 0.74
Identities = 20/61 (32%), Positives = 35/61 (57%)
Frame = +1
Query: 76 KMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
++++G P +GLGT+ G +++ L V+ A++ G H DT+ VY+ E+ IG
Sbjct: 32 RLSSGHNFPIVGLGTH-GLNED--------VLETVLTGALEKGIGHIDTSFVYKNEETIG 82
Query: 256 K 258
K
Sbjct: 83 K 83
>UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1;
Propionibacterium freudenreichii subsp. shermanii|Rep:
Putative aldo-keto reductase - Propionibacterium
freudenreichii subsp. shermanii
Length = 280
Score = 66.1 bits (154), Expect = 8e-10
Identities = 35/89 (39%), Positives = 50/89 (56%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
EAV V E R +IF+TTK H R V +A+ SL++LGLDY+DL+LMHWP+
Sbjct: 59 EAVGKAVREAGPDRAEIFVTTKFSKQWHSRKGVHEALEHSLERLGLDYVDLFLMHWPMPG 118
Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKA 521
Y ++ +RG+ + + G KA
Sbjct: 119 EGSY-------VDAYRGMVELKEQGLAKA 140
Score = 43.2 bits (97), Expect = 0.006
Identities = 23/68 (33%), Positives = 36/68 (52%)
Frame = +1
Query: 55 TMEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY 234
T P+++++ G MP +G+GT+ K ++ R V AI+ GYR DTA Y
Sbjct: 5 TTPTPTVELSGGTRMPMLGMGTW---------PLKGEECRAAVASAIEQGYRLVDTAEAY 55
Query: 235 ETEQEIGK 258
E+ +GK
Sbjct: 56 GNEEAVGK 63
>UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=9; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 308
Score = 66.1 bits (154), Expect = 8e-10
Identities = 46/153 (30%), Positives = 73/153 (47%), Gaps = 17/153 (11%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI-----GLNADYSH 452
+KRE+I+IT+KLWNT HR V +A +LK L LDY+DLYLMH+P G+ +
Sbjct: 60 IKRENIWITSKLWNTHHRLEIVEEACRKTLKDLRLDYLDLYLMHYPFAFQNTGIGGSLNP 119
Query: 453 SD----------VDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK* 602
D V ++TW+ +E G +K T + K + + +
Sbjct: 120 LDEKGNTIFDDGVSLIDTWKAMEKLVEKGLVKRIGVSNWTINQLERL-KYSDAKTTPYTN 178
Query: 603 RVTSKTFQKE--MVEFCQSESVVVMGYSPFRFP 695
+V + ++ + E+ E ++V GYS P
Sbjct: 179 QVEFNLYMQQGPLREYMHKEGIIVTGYSTLGTP 211
>UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8;
Saccharomycetaceae|Rep: Glycerol dehydrogenase -
Zygosaccharomyces rouxii (Candida mogii)
Length = 310
Score = 66.1 bits (154), Expect = 8e-10
Identities = 43/157 (27%), Positives = 77/157 (49%), Gaps = 20/157 (12%)
Frame = +3
Query: 273 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADY-- 446
+++ V R +IF+TTKLW T R + +A++ SL++LGLDY+ LYL+HWP+ L +
Sbjct: 65 IQDSGVPRNEIFLTTKLWCTHQRNPQ--EALDQSLQRLGLDYVGLYLVHWPVPLRTENIK 122
Query: 447 ------------SHSDVD----FMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKAL 578
DVD F++TW ++ G KA + ++ +
Sbjct: 123 DGNLFQFAEKPDGSKDVDLEWNFIKTWELMQKLLESGKTKAIGVSNFSVNNLKDLLAAPT 182
Query: 579 SNLMLFK*RVTSKTF--QKEMVEFCQSESVVVMGYSP 683
+ + +V Q+E++++C + +V+ YSP
Sbjct: 183 TKVTPAVNQVEFHPLLPQEELIQYCSEKGIVIEAYSP 219
Score = 50.0 bits (114), Expect = 6e-05
Identities = 25/63 (39%), Positives = 38/63 (60%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249
+LK+N G+ +P +GLGT+ +SK+ + V+ A+ GYRH D A+VY E E
Sbjct: 10 TLKLNTGQTIPQVGLGTW---------RSKENEGYKAVIEALKAGYRHIDGAAVYGNEGE 60
Query: 250 IGK 258
+GK
Sbjct: 61 VGK 63
>UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 234
Score = 66.1 bits (154), Expect = 8e-10
Identities = 28/54 (51%), Positives = 38/54 (70%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYS 449
VK DI++TTK+WN + + V ++NDSLKKL LDY+ L+L+HWPI YS
Sbjct: 104 VKGPDIWVTTKVWNHLYDKDGVQWSLNDSLKKLNLDYVGLFLIHWPISCEKAYS 157
>UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family;
n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto
reductase family - Lactobacillus acidophilus
Length = 289
Score = 65.7 bits (153), Expect = 1e-09
Identities = 48/147 (32%), Positives = 77/147 (52%), Gaps = 4/147 (2%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437
AV ++ V R+DIF+TTKLW + + ++AI++ LK+LG DYID+ L+H G
Sbjct: 57 AVGEAIKNSDVNRDDIFLTTKLWVSNFTYEKASKAIDEDLKELGTDYIDMMLLHQAYG-- 114
Query: 438 ADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSW--RGC*KKALSNLMLFK*RV- 608
D WR LEDAQ+ G K+ S+ W + + +SN+ ++
Sbjct: 115 --------DVAGAWRALEDAQKAGKTKS----IGVSNFWPDQLMNLQLMSNVKPVVNQIE 162
Query: 609 TSKTFQKE-MVEFCQSESVVVMGYSPF 686
+ FQ+E V++ Q + V V ++PF
Sbjct: 163 VNPWFQREPEVKWNQKDDVAVEAWAPF 189
Score = 39.1 bits (87), Expect = 0.10
Identities = 20/66 (30%), Positives = 34/66 (51%)
Frame = +1
Query: 61 EVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240
++P +K+N+G +P +G G + + + VK+ V AI GYR DTA Y
Sbjct: 3 DIPKIKLNDGNEIPQLGFGVFQISNHDEAVKA--------VESAISNGYRLIDTAEAYNN 54
Query: 241 EQEIGK 258
+ +G+
Sbjct: 55 QTAVGE 60
>UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto
reductase family 1, member B10, partial; n=1; Macaca
mulatta|Rep: PREDICTED: similar to aldo-keto reductase
family 1, member B10, partial - Macaca mulatta
Length = 275
Score = 65.3 bits (152), Expect = 1e-09
Identities = 48/156 (30%), Positives = 75/156 (48%), Gaps = 6/156 (3%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTK------LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 416
EA++ K++E VKRED+FI +K LW T R V +A +LK L L Y+D+YL+
Sbjct: 77 EAIQEKIQEQAVKREDLFIVSKVHMAHWLWTTFFERPLVRKAFEKTLKDLKLSYLDVYLI 136
Query: 417 HWPIGLNADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLF 596
HWP G A D GL A +G + + G K ++N +
Sbjct: 137 HWPQGFKAMEELVD-------EGLVKA--LGISNFNHFQIEKLLNKPGLKYKPVTNQVEC 187
Query: 597 K*RVTSKTFQKEMVEFCQSESVVVMGYSPFRFPGXP 704
+T Q++++++C S+ + + YSP P P
Sbjct: 188 HPYLT----QEKLIQYCHSKGITITAYSPLGSPDRP 219
Score = 39.5 bits (88), Expect = 0.079
Identities = 17/36 (47%), Positives = 24/36 (66%)
Frame = +1
Query: 151 KSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
KS ++++ V AID GYRH D A VY+ E E+G+
Sbjct: 42 KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGE 77
Score = 33.9 bits (74), Expect = 3.9
Identities = 18/37 (48%), Positives = 25/37 (67%), Gaps = 2/37 (5%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEGH 610
G+VK +G+SNFN Q+E++L K G KP Q+E H
Sbjct: 152 GLVKALGISNFNHFQIEKLLNKPGLKYKPVTNQVECH 188
>UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1;
Corynebacterium jeikeium K411|Rep: Putative
oxidoreductase - Corynebacterium jeikeium (strain K411)
Length = 285
Score = 65.3 bits (152), Expect = 1e-09
Identities = 30/56 (53%), Positives = 40/56 (71%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425
AV V+ G V+RE++FITTKLWN + +A +S KKLG+DY+DLYL+HWP
Sbjct: 64 AVADAVKAGDVQREELFITTKLWNADQACGK--EAFAESQKKLGMDYVDLYLLHWP 117
Score = 49.6 bits (113), Expect = 7e-05
Identities = 24/65 (36%), Positives = 38/65 (58%)
Frame = +1
Query: 64 VPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243
VP+L+MN+G+ P +GLG + + D+ V AI+ GYRH DTA++Y E
Sbjct: 8 VPTLEMNDGKTTPQLGLGVW---------QLSDEDTYTSVRAAIETGYRHIDTAAIYGNE 58
Query: 244 QEIGK 258
+ +G+
Sbjct: 59 EAVGR 63
>UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae
str. PEST
Length = 310
Score = 65.3 bits (152), Expect = 1e-09
Identities = 43/155 (27%), Positives = 73/155 (47%), Gaps = 12/155 (7%)
Frame = +3
Query: 255 EAVKMKVEE-GVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431
EA++ K+ E + R+D FI +KL + HR+ V + +L +LG+DY+DLYLMH P+
Sbjct: 61 EAIREKIRECNNLTRDDFFIISKLSGSYHRQDLVEKCCRMTLDRLGMDYVDLYLMHTPVA 120
Query: 432 LNADYS-----------HSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKAL 578
L ++ + E W GLE + G ++ A
Sbjct: 121 LQSEKKCARNGTKLNAIDDSIAPTEAWIGLEQCYQEGLCRSIGVSNFNEHQINALLSDAS 180
Query: 579 SNLMLFK*RVTSKTFQKEMVEFCQSESVVVMGYSP 683
+ + + Q+ M +FCQ ++++VMGY+P
Sbjct: 181 IVPAVNQIECSIGFNQRPMRKFCQQQNILVMGYTP 215
Score = 39.1 bits (87), Expect = 0.10
Identities = 22/54 (40%), Positives = 29/54 (53%)
Frame = +1
Query: 97 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
+P IGLGTY +G ++ + AIDVGYR FDTA Y E +G+
Sbjct: 17 LPTIGLGTYSILGADG---------KEAIRTAIDVGYRMFDTAVAYGNEAIVGE 61
Score = 37.1 bits (82), Expect = 0.42
Identities = 15/38 (39%), Positives = 24/38 (63%)
Frame = +2
Query: 491 RCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIE 604
+C G+ + IG+SNFN+ Q+ +L + +I P QIE
Sbjct: 152 QCYQEGLCRSIGVSNFNEHQINALLSDASIVPAVNQIE 189
>UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=4; Oligohymenophorea|Rep: Oxidoreductase,
aldo/keto reductase family protein - Tetrahymena
thermophila SB210
Length = 297
Score = 65.3 bits (152), Expect = 1e-09
Identities = 37/136 (27%), Positives = 71/136 (52%), Gaps = 4/136 (2%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA----DYSHS 455
+KRED+FIT+K+ + + +A+ D L +L + Y+D L+HWP G++ D ++
Sbjct: 77 IKREDLFITSKISPGEQGYEQAKKAVQDMLTRLNIKYLDCVLIHWP-GVSKLPPNDPKNA 135
Query: 456 DVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTSKTFQKEM 635
+ +ETW+ L + ++ G +K + + +K+ + + + F K+
Sbjct: 136 QIR-LETWKALIELRKAGVIKHIGVSNFNINHLQHLIEKSEFKPEMNQFEIHPLCFNKKT 194
Query: 636 VEFCQSESVVVMGYSP 683
+EFCQ ++V YSP
Sbjct: 195 IEFCQKNGILVEAYSP 210
Score = 45.6 bits (103), Expect = 0.001
Identities = 27/67 (40%), Positives = 34/67 (50%)
Frame = +1
Query: 58 MEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237
++VP L G +P IG GTY QN + V A+ +GY H DTASVY
Sbjct: 11 VKVPILNFREGGSIPQIGYGTY-ELRQNDCIIG--------VTEALKIGYTHIDTASVYR 61
Query: 238 TEQEIGK 258
EQ+I K
Sbjct: 62 NEQDIAK 68
>UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein T08H10.1 - Caenorhabditis elegans
Length = 333
Score = 65.3 bits (152), Expect = 1e-09
Identities = 45/154 (29%), Positives = 70/154 (45%), Gaps = 12/154 (7%)
Frame = +3
Query: 273 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL------ 434
+ G +KREDIF+T+KL T H +V + + LK L L+YIDLYL+H P
Sbjct: 65 ISSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLYLIHCPFPFKHQEGS 124
Query: 435 ------NADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLF 596
N + + +++ ++TWR LE + G LKA + + + A
Sbjct: 125 FAPLMENGELAVTEIAHIDTWRALEKLYKEGKLKALGVSNFSCNQLQALYDAAEVKPANQ 184
Query: 597 K*RVTSKTFQKEMVEFCQSESVVVMGYSPFRFPG 698
+ Q+E+ C+ V V Y+P PG
Sbjct: 185 QVECHIYWPQQELRALCKKLGVTVTAYAPLGSPG 218
Score = 44.4 bits (100), Expect = 0.003
Identities = 27/68 (39%), Positives = 37/68 (54%), Gaps = 1/68 (1%)
Frame = +1
Query: 58 MEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRA-IDVGYRHFDTASVY 234
M V S+ +N G +P GLGT+ + KD+ V +RA +D GYR DTA +Y
Sbjct: 1 MTVDSIPLNTGAQLPLFGLGTW---------QVKDEAELTVALRAALDAGYRLIDTAHLY 51
Query: 235 ETEQEIGK 258
+ E IGK
Sbjct: 52 QNEHIIGK 59
>UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;
n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
hypothetical protein - Ornithorhynchus anatinus
Length = 419
Score = 64.9 bits (151), Expect = 2e-09
Identities = 29/74 (39%), Positives = 46/74 (62%)
Frame = +3
Query: 273 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH 452
++E VKRE+++ITTKLW T + Q+ +S +LG++Y+DL+L+HWP S
Sbjct: 69 IQESGVKREELWITTKLWLTDYGYESAKQSCLESCNRLGVEYLDLFLIHWPDAQLPGKSS 128
Query: 453 SDVDFMETWRGLED 494
+ ETWR +E+
Sbjct: 129 REAR-AETWRAMEE 141
>UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep:
Lin2848 protein - Listeria innocua
Length = 280
Score = 64.9 bits (151), Expect = 2e-09
Identities = 32/78 (41%), Positives = 44/78 (56%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDF 467
+KR++ F+TTK+WNT+ E +A S KKL LD +DLYL+HWP F
Sbjct: 69 LKRDEFFVTTKMWNTEQGYDETLRAFEKSQKKLQLDQVDLYLVHWP---------KQDTF 119
Query: 468 METWRGLEDAQRMG*LKA 521
ETWR +E G ++A
Sbjct: 120 FETWRAVEKLYDEGLVRA 137
Score = 47.6 bits (108), Expect = 3e-04
Identities = 25/60 (41%), Positives = 35/60 (58%)
Frame = +1
Query: 76 KMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
++NNG MP G G Y D+ +++R + A+DVGYR FDTAS Y E+E+G
Sbjct: 10 RLNNGIEMPRHGFGVYKLTDE--------QRMRTALETAVDVGYRLFDTASFYHNEKELG 61
>UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein;
n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9
protein - Oryza sativa (Rice)
Length = 337
Score = 64.9 bits (151), Expect = 2e-09
Identities = 44/145 (30%), Positives = 69/145 (47%), Gaps = 12/145 (8%)
Frame = +3
Query: 285 VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA-------- 440
V R ++F+TTKL V A+ +SL +LGLDY+DL+L+HWP+ +
Sbjct: 87 VASRGELFVTTKLSMADAHPPRVVAALRESLSRLGLDYVDLFLIHWPVAIGKKDAAGELT 146
Query: 441 --DYSHSDVDF-ME-TWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RV 608
D S V F ME WRG+E+ R+G ++ +++ A + + +
Sbjct: 147 WDDLSRGLVPFDMEGVWRGMEECHRLGLARSIGVSNFSAAKMSRLLALAAVPPAVNQVEM 206
Query: 609 TSKTFQKEMVEFCQSESVVVMGYSP 683
Q+++ E C VVV YSP
Sbjct: 207 NVGWRQEKVREVCGEGGVVVAAYSP 231
Score = 45.2 bits (102), Expect = 0.002
Identities = 24/69 (34%), Positives = 35/69 (50%)
Frame = +1
Query: 49 ASTMEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTAS 228
A+ VP + +N+G MP +G GT + L + A+ +GYRH DTA+
Sbjct: 15 AAATAVPCVTLNSGHAMPVLGFGTGSS--------TPPADLAATIAHAVRLGYRHLDTAA 66
Query: 229 VYETEQEIG 255
VY TE +G
Sbjct: 67 VYGTEGAVG 75
>UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr1 scaffold_22, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 360
Score = 64.9 bits (151), Expect = 2e-09
Identities = 45/150 (30%), Positives = 75/150 (50%), Gaps = 12/150 (8%)
Frame = +3
Query: 282 GVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP----IGLNAD-Y 446
G +KRED+F+T+KL+ T + ++ ++ SLK LG+ Y+DLYLMHWP G D
Sbjct: 72 GSLKREDVFLTSKLYCTMNSLNKIENSVRVSLKNLGVTYLDLYLMHWPDITAFGDATDPP 131
Query: 447 SHSDVD-------FMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*R 605
S+S D + W+ +E +G ++A + K A + + +
Sbjct: 132 SNSGNDHRQFLNRLKKAWKAMEGLIELGLVRAIGVSNFGVQQIKELLKFAKIVPAVNQVK 191
Query: 606 VTSKTFQKEMVEFCQSESVVVMGYSPFRFP 695
+ Q E+V+FCQS+ + V ++P P
Sbjct: 192 LHPFWRQDELVKFCQSKGIHVSAHTPLGVP 221
Score = 34.3 bits (75), Expect = 3.0
Identities = 21/60 (35%), Positives = 30/60 (50%)
Frame = +1
Query: 79 MNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
+N +PAIGLGT+ +S + V RA+ GYR D A +Y E E+G+
Sbjct: 14 LNTKAKIPAIGLGTW---------QSGGDLCVEAVKRALSEGYRQIDCAHLYGNEVEVGE 64
Score = 34.3 bits (75), Expect = 3.0
Identities = 15/35 (42%), Positives = 23/35 (65%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
G+V+ IG+SNF QQ++ +LK I P Q++ H
Sbjct: 159 GLVRAIGVSNFGVQQIKELLKFAKIVPAVNQVKLH 193
>UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 321
Score = 64.9 bits (151), Expect = 2e-09
Identities = 27/57 (47%), Positives = 40/57 (70%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428
++K +EG +KREDIF T+KLWN+ H V + +++ LG+ Y+DLYL+HWPI
Sbjct: 71 SLKEIFKEGEIKREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPI 127
Score = 43.6 bits (98), Expect = 0.005
Identities = 23/62 (37%), Positives = 36/62 (58%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249
+ K+N+G +P+IGLGTY + +N ++ D + A+ GYRH D A+ Y E+
Sbjct: 16 NFKLNDGNQIPSIGLGTY--YSEN------PGEVGDAINNALKNGYRHIDGAAFYGNEKV 67
Query: 250 IG 255
IG
Sbjct: 68 IG 69
Score = 36.7 bits (81), Expect = 0.56
Identities = 18/35 (51%), Positives = 22/35 (62%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
G+VK IG+SNFN Q L +L IKP Q+E H
Sbjct: 170 GLVKSIGVSNFNVQNLVDLLTYAKIKPVVNQVEIH 204
>UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Lactobacillus acidophilus
Length = 278
Score = 64.5 bits (150), Expect = 2e-09
Identities = 36/89 (40%), Positives = 50/89 (56%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
+AV ++ V REDIFIT+K+W + +A +DS+KKL LDYIDLYL+H P
Sbjct: 54 QAVGDAIKHSNVPREDIFITSKIWVDDYGYDNTLKAFDDSMKKLQLDYIDLYLIHKPYN- 112
Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKA 521
D+ TWR LE + G ++A
Sbjct: 113 ---------DYYGTWRALERLYQEGRIRA 132
Score = 39.9 bits (89), Expect = 0.060
Identities = 23/59 (38%), Positives = 30/59 (50%)
Frame = +1
Query: 79 MNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
+NNG MP +G G Y D Q + VV ++VGYR DTA +Y EQ +G
Sbjct: 7 LNNGIKMPRLGFGVYQIDDL--------AQAQQVVEDGLEVGYRLVDTAQIYGNEQAVG 57
>UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2;
Lactobacillus reuteri|Rep: 2,5-didehydrogluconate
reductase - Lactobacillus reuteri F275
Length = 300
Score = 64.5 bits (150), Expect = 2e-09
Identities = 41/132 (31%), Positives = 65/132 (49%), Gaps = 1/132 (0%)
Frame = +3
Query: 291 KREDIFITTKLWN-TQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDF 467
KR+ IF+TTK++N Q ++ QA+N+ LKKL +Y+DL L+HWP+ N Y+
Sbjct: 77 KRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLLLHWPV--NDKYN------ 128
Query: 468 METWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTSKTFQKEMVEFC 647
E+WR LED + G KA A + + Q ++V+FC
Sbjct: 129 -ESWRALEDIYKDGQAKAIGVCNFNVERMTDLLDHAKIKPAINQIEFNPLIHQPKIVKFC 187
Query: 648 QSESVVVMGYSP 683
+ + + +SP
Sbjct: 188 RENDIQLEAWSP 199
Score = 33.5 bits (73), Expect = 5.2
Identities = 20/64 (31%), Positives = 31/64 (48%)
Frame = +1
Query: 67 PSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 246
P +K+NNG +P +GLG + K+ + + +V AI Y DTA Y E
Sbjct: 11 PKIKLNNGHLIPQLGLGVW---------KASLAETQQMVKEAIMNDYVLIDTAKQYGNEA 61
Query: 247 EIGK 258
+G+
Sbjct: 62 AVGQ 65
>UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=2; Tetrahymena thermophila SB210|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 332
Score = 64.5 bits (150), Expect = 2e-09
Identities = 40/144 (27%), Positives = 73/144 (50%), Gaps = 1/144 (0%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG- 431
E++K +EG R+D+FI +K++ ++ + +++ SLK+L LDY+DLY +H+P+G
Sbjct: 61 ESLKTIFKEGKYSRKDLFIVSKVF--PNKGINMLESVKKSLKELQLDYVDLYYLHFPLGF 118
Query: 432 LNADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVT 611
L+ + W LE+A R+G K+ + A + + V+
Sbjct: 119 LSEKEEFVHLPVHVAWAQLEEAHRLGLAKSIGVSNFNVMALADLLSYAKVKPVSNQVEVS 178
Query: 612 SKTFQKEMVEFCQSESVVVMGYSP 683
QK +++FCQ + V Y+P
Sbjct: 179 VFIQQKNLIKFCQRFGIHVTAYAP 202
Score = 54.4 bits (125), Expect = 3e-06
Identities = 28/63 (44%), Positives = 41/63 (65%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249
S K+NNG+ MP +GLGTYL + SK+ ++ +++ A+D GYRH DTA Y+ E
Sbjct: 7 SSKLNNGQIMPLVGLGTYL-------LNSKE-EMTNLLRTALDAGYRHIDTAVNYQNEAM 58
Query: 250 IGK 258
IG+
Sbjct: 59 IGE 61
>UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Arthrobacter sp. (strain FB24)
Length = 291
Score = 64.1 bits (149), Expect = 3e-09
Identities = 29/78 (37%), Positives = 45/78 (57%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDF 467
+ RED+F+TTK+WN H +A + S+ LG++Y+DLYL+HWP F
Sbjct: 83 LSREDLFVTTKVWNDDHGYDATMRAFDTSMSNLGMEYVDLYLIHWPCARRG-------LF 135
Query: 468 METWRGLEDAQRMG*LKA 521
E++R +E R G ++A
Sbjct: 136 TESYRAMETLYREGRIRA 153
Score = 42.7 bits (96), Expect = 0.009
Identities = 23/64 (35%), Positives = 32/64 (50%)
Frame = +1
Query: 67 PSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 246
P L +NNG + +G G Y K +V A++ GYRHFDTA++Y E
Sbjct: 5 PRLSLNNGVLIDQLGFGLY---------KVPPADAAGLVTMALEAGYRHFDTAAMYGNET 55
Query: 247 EIGK 258
+GK
Sbjct: 56 GVGK 59
>UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein;
n=1; Thermoplasma acidophilum|Rep: Alcohol dehydrogenase
related protein - Thermoplasma acidophilum
Length = 284
Score = 64.1 bits (149), Expect = 3e-09
Identities = 41/134 (30%), Positives = 70/134 (52%), Gaps = 3/134 (2%)
Frame = +3
Query: 291 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFM 470
+RED+FI TK+W T +V ++ +SLKKLG DY+DLY +HWP + S S + M
Sbjct: 68 RREDLFIATKVWPTHFAYHDVLKSCEESLKKLGTDYVDLYQLHWP-----NPSVSIKETM 122
Query: 471 ETWRGLEDAQRMG*LKASD-CLTSTSSSWRGC*K-KALSNLMLFK*RVTSKTFQKE-MVE 641
L D R+ + S+ + + K + +SN + + V ++ + E + +
Sbjct: 123 SAMEKLVDEGRIRYIGISNFSVKEMKEAMSALAKYRIVSNQLEY--NVATREIEDEGIYD 180
Query: 642 FCQSESVVVMGYSP 683
FC+ + ++ YSP
Sbjct: 181 FCRKNGMAIIAYSP 194
>UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2;
Actinomycetales|Rep: Putative oxidoreductase -
Streptomyces coelicolor
Length = 277
Score = 63.7 bits (148), Expect = 4e-09
Identities = 25/51 (49%), Positives = 35/51 (68%)
Frame = +3
Query: 294 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADY 446
RED+F+TTKLWN+ +A + S+ KLGL+Y+DLYL+HWP+ Y
Sbjct: 69 REDLFVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYLDLYLIHWPMPAKERY 119
Score = 40.3 bits (90), Expect = 0.045
Identities = 21/66 (31%), Positives = 34/66 (51%)
Frame = +1
Query: 61 EVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240
+VP + +NNG MP +G G + + D + V A++ GYR DTA++Y
Sbjct: 4 KVPPIILNNGVEMPQLGFGVW---------QVPDDDAQTAVALALEAGYRSIDTAAIYGN 54
Query: 241 EQEIGK 258
E+ G+
Sbjct: 55 EEGTGR 60
Score = 34.7 bits (76), Expect = 2.3
Identities = 17/37 (45%), Positives = 24/37 (64%)
Frame = +2
Query: 500 ANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
A+G V+ IG+SNF + LER+ E ++ P QIE H
Sbjct: 131 ADGRVRAIGVSNFLPEHLERLTAETSVIPAVNQIELH 167
>UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14;
Dikarya|Rep: Aldo-keto reductase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 353
Score = 63.7 bits (148), Expect = 4e-09
Identities = 41/164 (25%), Positives = 77/164 (46%), Gaps = 14/164 (8%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
+ V + +++ V R +IF+T+K+W++ H R E + ++ +LK L DY+DLYL+HWP+ L
Sbjct: 87 DEVGLGIKDSGVPRSEIFLTSKVWSSYHDRVE--ECLDTTLKSLQTDYLDLYLIHWPVRL 144
Query: 435 NADYSHS--------------DVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KK 572
+ +H D D +TW +ED + G KA + K
Sbjct: 145 APNGTHPLFPVKPDGSRNLDWDWDQAKTWAQMEDVLKKGKAKAIGLSNAGIPIIEHIIKT 204
Query: 573 ALSNLMLFK*RVTSKTFQKEMVEFCQSESVVVMGYSPFRFPGXP 704
+ + + Q ++++C+ + +++ YSP P
Sbjct: 205 GKVTPAVNQVELHPYCPQHALLKYCKEKGILLEAYSPLGSTSSP 248
Score = 49.2 bits (112), Expect = 1e-04
Identities = 27/67 (40%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
Frame = +1
Query: 58 MEVP-SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY 234
M P S K+N G +PAIGLGT+ ++K ++R V A+ GYRH D A Y
Sbjct: 33 MSAPTSFKLNTGASIPAIGLGTW---------QAKAGEVRQAVAHALKAGYRHIDGALCY 83
Query: 235 ETEQEIG 255
+ E E+G
Sbjct: 84 QNEDEVG 90
>UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5;
Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative
- Neosartorya fischeri (strain ATCC 1020 / DSM 3700 /
NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 /
DSM 3700 / NRRL 181))
Length = 321
Score = 63.7 bits (148), Expect = 4e-09
Identities = 27/60 (45%), Positives = 38/60 (63%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
+ V ++EG+VKRED+FI +KLWN+ H V L GLDY DL+++H+PI L
Sbjct: 58 KGVARAIQEGIVKREDLFIVSKLWNSFHDGDRVEPICRKQLADWGLDYFDLFIVHFPIAL 117
Score = 41.9 bits (94), Expect = 0.015
Identities = 25/67 (37%), Positives = 32/67 (47%)
Frame = +1
Query: 58 MEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237
M PS K+N+G MP +G G + K ++ D + AI GYR FD A Y
Sbjct: 1 MTTPSTKLNSGYDMPLVGFGLW---------KVNNETCADQIYHAIKAGYRLFDGACDYG 51
Query: 238 TEQEIGK 258
E E GK
Sbjct: 52 NEVEAGK 58
Score = 33.9 bits (74), Expect = 3.9
Identities = 16/41 (39%), Positives = 24/41 (58%)
Frame = +2
Query: 509 IVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGHLQNVSER 631
+ + IG+SNF+ Q L +L+ I+P +QIE H ER
Sbjct: 159 LARSIGVSNFSAQLLMDLLRYARIRPATLQIEHHPYLTQER 199
>UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like
protein 1; n=14; Eutheria|Rep: Aldo-keto reductase
family 1 member C-like protein 1 - Homo sapiens (Human)
Length = 302
Score = 63.7 bits (148), Expect = 4e-09
Identities = 29/60 (48%), Positives = 40/60 (66%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
+A+ K+ +G VKRE+IF T KLW T R V A+ SLKKLG DY+DL+++H P +
Sbjct: 66 QAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAM 125
Score = 49.6 bits (113), Expect = 7e-05
Identities = 25/63 (39%), Positives = 40/63 (63%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249
S+++N+G MP +G GTY + KS+ + V AIDVG+RH D+A +Y+ E+E
Sbjct: 10 SVRLNDGPFMPVLGFGTYA---PDHTPKSQAAEATKV---AIDVGFRHIDSAYLYQNEEE 63
Query: 250 IGK 258
+G+
Sbjct: 64 VGQ 66
>UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase
family; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 307
Score = 63.3 bits (147), Expect = 6e-09
Identities = 40/137 (29%), Positives = 67/137 (48%), Gaps = 7/137 (5%)
Frame = +3
Query: 294 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHS------ 455
RE++F+T+KLW Q T + ++ +S++ L Y+DLYL+HWPI L D S+
Sbjct: 70 REELFVTSKLWMDQV--TRIRESCLESIQDLKCKYLDLYLIHWPIALKVDASNPPKPEDF 127
Query: 456 -DVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTSKTFQKE 632
D+D E W+ +E G +K+ T K ++ + + Q +
Sbjct: 128 LDMDITEIWQEMERLVDEGLVKSIGLSNFTIPQIEKIMKMCRIKPVINQVELNVYLQQNK 187
Query: 633 MVEFCQSESVVVMGYSP 683
+ E C+S ++VV Y P
Sbjct: 188 LREVCKSYNIVVEAYRP 204
Score = 42.7 bits (96), Expect = 0.009
Identities = 24/60 (40%), Positives = 35/60 (58%)
Frame = +1
Query: 79 MNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
+NNG+ MPAIGLGT+L + ++ V A++ GYR D A Y+ E+EIG+
Sbjct: 8 LNNGKFMPAIGLGTWL---------AAPGEVGKAVTLALENGYRLIDCARFYKNEKEIGE 58
>UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core
eudicotyledons|Rep: T2K10.1 protein - Arabidopsis
thaliana (Mouse-ear cress)
Length = 176
Score = 63.3 bits (147), Expect = 6e-09
Identities = 35/94 (37%), Positives = 49/94 (52%), Gaps = 9/94 (9%)
Frame = +3
Query: 255 EAVKMKVEEGVVK-REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431
EA+ V G+V+ R + F+TTKLW V AI SLK L LDY+DLY++HWP+
Sbjct: 68 EALAEAVSLGLVRSRSEFFVTTKLWCADAHGGLVVPAIKRSLKNLKLDYLDLYIIHWPVS 127
Query: 432 LNA--------DYSHSDVDFMETWRGLEDAQRMG 509
+ +DF W +E+ QR+G
Sbjct: 128 SKPGKYKFPIDEDDFMPMDFEVVWSEMEECQRLG 161
Score = 44.0 bits (99), Expect = 0.004
Identities = 26/73 (35%), Positives = 39/73 (53%), Gaps = 4/73 (5%)
Frame = +1
Query: 52 STMEVPSLKMNNG----RXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFD 219
S VP+L + +G MP +G GT + L++ V+ AI +GYRHFD
Sbjct: 2 SLTTVPTLAIRSGPSGHHSMPVLGFGTAAS------PLPEPTMLKETVIEAIKLGYRHFD 55
Query: 220 TASVYETEQEIGK 258
T+ Y+TE+ IG+
Sbjct: 56 TSPRYQTEEPIGE 68
>UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Yersinia pestis
Length = 277
Score = 63.3 bits (147), Expect = 6e-09
Identities = 28/57 (49%), Positives = 38/57 (66%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425
E V ++ V R+++FITTKLWN + QA+ SL+KL LDY+DLYL+HWP
Sbjct: 55 EGVGKALKAAAVARDELFITTKLWNDDQHNPQ--QALETSLQKLQLDYVDLYLIHWP 109
Score = 46.4 bits (105), Expect = 7e-04
Identities = 24/68 (35%), Positives = 42/68 (61%)
Frame = +1
Query: 55 TMEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY 234
TM+ P +K+ +GR MP +GLG + ++ ++ V +A++VGYR DTA++Y
Sbjct: 2 TMQ-PLIKLYDGRLMPQLGLGVW---------QASIQETELAVSKALEVGYRSIDTAAIY 51
Query: 235 ETEQEIGK 258
+ E+ +GK
Sbjct: 52 KNEEGVGK 59
>UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Staphylococcus|Rep: Oxidoreductase,
aldo/keto reductase family - Staphylococcus epidermidis
(strain ATCC 35984 / RP62A)
Length = 279
Score = 62.9 bits (146), Expect = 7e-09
Identities = 31/89 (34%), Positives = 52/89 (58%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
+A+ ++ V+R+++FIT+KLWN + + N SL LGLDY+DL+L+HWP
Sbjct: 54 KALGSALKHSNVERDELFITSKLWNDYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWP--- 110
Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKA 521
+D ++E+++ LE G +KA
Sbjct: 111 ----CENDQLYIESYKALEHLYEEGKIKA 135
Score = 52.4 bits (120), Expect = 1e-05
Identities = 27/59 (45%), Positives = 35/59 (59%)
Frame = +1
Query: 79 MNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
+NNG MPA+GLG Y K D+Q+ +VV A+D GYR FDTA Y E+ +G
Sbjct: 8 LNNGYPMPAVGLGVY---------KIADEQMEEVVRTALDAGYRAFDTAYFYGNEKALG 57
Score = 34.7 bits (76), Expect = 2.3
Identities = 16/35 (45%), Positives = 21/35 (60%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
G +K IG+ NF LE+++KE I P QIE H
Sbjct: 131 GKIKAIGVCNFKIHHLEKLMKETKITPQVNQIELH 165
>UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1;
Parvularcula bermudensis HTCC2503|Rep: Putative
uncharacterized protein - Parvularcula bermudensis
HTCC2503
Length = 278
Score = 62.9 bits (146), Expect = 7e-09
Identities = 25/57 (43%), Positives = 43/57 (75%), Gaps = 4/57 (7%)
Frame = +3
Query: 270 KVEEGV----VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428
KV EG+ + R+++F+TTK+WN ++ ++A+++SL +LGLDY++L L+HWPI
Sbjct: 52 KVGEGIKDSGIPRDELFVTTKIWNEDIQKGRHSEAVDESLDRLGLDYVNLILLHWPI 108
Score = 34.7 bits (76), Expect = 2.3
Identities = 16/45 (35%), Positives = 27/45 (60%)
Frame = +1
Query: 124 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
LGF G + + + R AI+ GYRH D A++Y+ E+++G+
Sbjct: 14 LGF---GTWQLEGEDARTSTRTAIETGYRHIDGAAIYKNEKKVGE 55
>UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr1 scaffold_5, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 247
Score = 62.9 bits (146), Expect = 7e-09
Identities = 36/99 (36%), Positives = 55/99 (55%), Gaps = 10/99 (10%)
Frame = +3
Query: 255 EAVKMKVEEGVVK-REDIFITTKLWNTQHRRTEVAQAINDSLK---------KLGLDYID 404
EA+K V+ G++K R+++FIT+KLW + V A+ ++LK L LDY+D
Sbjct: 63 EAIKKAVKLGLIKSRDELFITSKLWCSDAHHDRVLPALQNTLKISSILSFSKNLQLDYLD 122
Query: 405 LYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMG*LKA 521
LYL+HW G H +D W+ +ED Q++ KA
Sbjct: 123 LYLIHWSDG------HLPIDLGSVWKAMEDFQKLSLTKA 155
Score = 35.5 bits (78), Expect = 1.3
Identities = 17/68 (25%), Positives = 39/68 (57%), Gaps = 1/68 (1%)
Frame = +1
Query: 58 MEVPSLKMNN-GRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY 234
+ +P + + + G+ +P +G+ T + + + + D ++ AI++GYRHFD + Y
Sbjct: 2 ISIPEMTLGSTGKAIPLVGMVTTV------YPFAPSETMIDSILTAIELGYRHFDCVAAY 55
Query: 235 ETEQEIGK 258
+E+ +G+
Sbjct: 56 LSEKPLGE 63
>UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 268
Score = 62.5 bits (145), Expect = 1e-08
Identities = 41/142 (28%), Positives = 65/142 (45%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437
AV ++ + R D+FIT+K+WN + A + +L L LDY+DLYL+HWP N
Sbjct: 53 AVGEAIKASGIDRSDLFITSKVWNADQGYDKTLAAFDQTLSDLQLDYLDLYLIHWP---N 109
Query: 438 ADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTSK 617
D +D TWR LE + ++A + + + A M+ +
Sbjct: 110 EDDFELTLD---TWRVLETLYQQKKVRAIGVSNFSEDQLKQVFEMATVKPMINQIERHPY 166
Query: 618 TFQKEMVEFCQSESVVVMGYSP 683
Q ++ +F +V GYSP
Sbjct: 167 KVQADLGQFDTDNDIVNEGYSP 188
Score = 42.3 bits (95), Expect = 0.011
Identities = 22/61 (36%), Positives = 34/61 (55%)
Frame = +1
Query: 76 KMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
+++NG +P +G GTYL + SKD + + A+D GYRH D A +Y E +G
Sbjct: 5 QLSNGVTIPMLGFGTYL-------IDSKD--VPAAIKTALDAGYRHLDCAHIYGNEPAVG 55
Query: 256 K 258
+
Sbjct: 56 E 56
>UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia
ATCC 50803
Length = 303
Score = 62.5 bits (145), Expect = 1e-08
Identities = 27/61 (44%), Positives = 43/61 (70%), Gaps = 4/61 (6%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL----NADYSHS 455
VKRED++I +KLW H +VA I+++L+ L L+Y+D++LMHWP+ + + DY+ S
Sbjct: 59 VKREDLWIVSKLWPNFHEPEKVAYQISETLRDLQLEYLDVFLMHWPLAIKHLADRDYASS 118
Query: 456 D 458
D
Sbjct: 119 D 119
>UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6;
Pezizomycotina|Rep: Aldo/keto reductase family proteins
- Aspergillus oryzae
Length = 294
Score = 62.5 bits (145), Expect = 1e-08
Identities = 41/148 (27%), Positives = 72/148 (48%), Gaps = 4/148 (2%)
Frame = +3
Query: 273 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH 452
++E + RE++F+TTK+ ++ AI+ SL+KL L+Y+DLYL+H P ++
Sbjct: 75 IKESGIPREELFVTTKVITNI---ADIPSAIDQSLRKLQLNYVDLYLIHSPF-----FAK 126
Query: 453 SDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTSKTFQKE 632
SD + + W +E Q+ G KA S K A+ ++ + Q+E
Sbjct: 127 SDGELQQAWAAMEKVQQAGKAKAIGVSNYHQSHLEATLKTAVIAPVINQIEHHPYLQQEE 186
Query: 633 MVEFCQSESVVVMGYSP----FRFPGXP 704
++ F + + + + Y P R PG P
Sbjct: 187 LLRFQREKDIKIASYGPLTPILRAPGGP 214
Score = 50.0 bits (114), Expect = 6e-05
Identities = 24/68 (35%), Positives = 38/68 (55%)
Frame = +1
Query: 52 STMEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASV 231
S P +K+N+ +P +G GT + + S +++L + + AI +GYRH D A V
Sbjct: 5 SIPNTPRVKLNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGAEV 64
Query: 232 YETEQEIG 255
Y TE E+G
Sbjct: 65 YGTEAELG 72
>UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep:
Aldehyde reductase - Leptospira interrogans
Length = 278
Score = 62.1 bits (144), Expect = 1e-08
Identities = 24/56 (42%), Positives = 39/56 (69%)
Frame = +3
Query: 261 VKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428
V + E + R++IFITTKLWN + +A+ +SL +LG+D++DLYL+H+P+
Sbjct: 63 VGQAIRESGIPRKEIFITTKLWNADQGSDKTRKALENSLDRLGIDFVDLYLIHFPV 118
Score = 49.6 bits (113), Expect = 7e-05
Identities = 23/64 (35%), Positives = 40/64 (62%), Gaps = 1/64 (1%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKD-KQLRDVVMRAIDVGYRHFDTASVYETEQ 246
++ +NNG MP +GLG + K+K K+ ++ V+ A++ GYRH DTA +Y+ E
Sbjct: 11 TIMLNNGISMPILGLGVW---------KTKSGKECKEAVLNALEAGYRHIDTARIYDNEV 61
Query: 247 EIGK 258
++G+
Sbjct: 62 DVGQ 65
>UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC
1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase);
n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid
4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid
5-beta-reductase) - Homo sapiens (Human)
Length = 326
Score = 62.1 bits (144), Expect = 1e-08
Identities = 45/160 (28%), Positives = 71/160 (44%), Gaps = 17/160 (10%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
EA++ K+ EG V+REDIF KLW T H V + +L+ L LDY+DLY++ P+
Sbjct: 66 EAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAF 125
Query: 435 -----------NADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWR------GC 563
N + + + TW +E + G +K+ G
Sbjct: 126 KPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGL 185
Query: 564 *KKALSNLMLFK*RVTSKTFQKEMVEFCQSESVVVMGYSP 683
K +SN + T Q ++++FCQ +V+ YSP
Sbjct: 186 KHKPVSNQVECHPYFT----QPKLLKFCQQHDIVITAYSP 221
Score = 43.2 bits (97), Expect = 0.006
Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 1/63 (1%)
Frame = +1
Query: 73 LKMNNGRXMPAIGLGTYLGFDQNGVVKSKDK-QLRDVVMRAIDVGYRHFDTASVYETEQE 249
+ +++G +P IGLGTY KS K V AID GYRH D A +Y+ E E
Sbjct: 10 IPLSDGNSIPIIGLGTY------SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHE 63
Query: 250 IGK 258
+G+
Sbjct: 64 VGE 66
Score = 38.7 bits (86), Expect = 0.14
Identities = 18/41 (43%), Positives = 28/41 (68%), Gaps = 2/41 (4%)
Frame = +2
Query: 494 CSANGIVKGIGLSNFNKQQLERVLKEGTI--KPDAIQIEGH 610
C G+VK +G+SNFN++QLE +L + + KP + Q+E H
Sbjct: 157 CKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECH 197
>UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus
coagulans 36D1|Rep: Aldo/keto reductase - Bacillus
coagulans 36D1
Length = 273
Score = 61.7 bits (143), Expect = 2e-08
Identities = 39/146 (26%), Positives = 70/146 (47%), Gaps = 3/146 (2%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH--WPI 428
E+V V + + R DIF+T+KL + + ++++ GL+ +DLYL+H WP
Sbjct: 57 ESVGKAVRDSGIDRRDIFVTSKLPAEIKSYDKALKTFDETMGNFGLEQLDLYLIHAPWPW 116
Query: 429 G-LNADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*R 605
ADY+ ++ E W+ +E+ G +A + S + + A M+ + R
Sbjct: 117 SEKGADYTKENI---EVWKAMEEIYESGRCRAIGVSNFSVSDLKAVMENAKIKPMVNQIR 173
Query: 606 VTSKTFQKEMVEFCQSESVVVMGYSP 683
Q+++ FCQ ++V YSP
Sbjct: 174 YFIGHTQEDVTAFCQDNGILVEAYSP 199
Score = 36.7 bits (81), Expect = 0.56
Identities = 23/60 (38%), Positives = 30/60 (50%)
Frame = +1
Query: 79 MNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
+ NG +P IGLGT+ NG + V A+ GYRH DTA Y E+ +GK
Sbjct: 10 LENGVAIPKIGLGTWQV--PNG------ETTYHAVSFALKNGYRHIDTAYAYHNEESVGK 61
>UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 285
Score = 61.3 bits (142), Expect = 2e-08
Identities = 34/89 (38%), Positives = 49/89 (55%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
E V +++ +KREDIFITTK+W + + +I+ SLKKL +YIDL L+H P G
Sbjct: 53 EFVGNAIKQTKIKREDIFITTKVWISNYGYNNTMYSISKSLKKLQTNYIDLVLLHQPFG- 111
Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKA 521
D+ W+ LE + G +KA
Sbjct: 112 ---------DYYSAWKALEVLYKKGIVKA 131
Score = 41.9 bits (94), Expect = 0.015
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 1/62 (1%)
Frame = +1
Query: 73 LKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAID-VGYRHFDTASVYETEQE 249
+K+ NG MP IGLG Y K++ + + +++AID GYR DTA VY E+
Sbjct: 4 IKLANGLHMPIIGLGVY---------KAEGENCENTIIKAIDDYGYRMIDTAQVYFNEEF 54
Query: 250 IG 255
+G
Sbjct: 55 VG 56
>UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 288
Score = 61.3 bits (142), Expect = 2e-08
Identities = 34/101 (33%), Positives = 54/101 (53%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
+ V +++ + R+ I++T+KLW + ++AI+ SL KL LDYIDLYL+H P G
Sbjct: 56 DEVGQAIKDSGIPRDQIWVTSKLWLQDYGFDAASRAIDRSLTKLRLDYIDLYLIHQPYG- 114
Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWR 557
D W+ +E AQ+ G LK+ T + W+
Sbjct: 115 ---------DVPGAWQAMEAAQKAGKLKSIGVSNMTPTLWQ 146
Score = 48.0 bits (109), Expect = 2e-04
Identities = 24/66 (36%), Positives = 37/66 (56%)
Frame = +1
Query: 61 EVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240
+ P++ +N+GR +PAIG GT+ D ++ V A+ +GYRH DTA Y
Sbjct: 3 KTPTITLNDGRAIPAIGFGTFQIPDDGSTYQA--------VKEALVIGYRHIDTAVAYFN 54
Query: 241 EQEIGK 258
E E+G+
Sbjct: 55 EDEVGQ 60
>UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293|Rep: Aldo/keto reductase of
diketogulonate reductase family - Leuconostoc
mesenteroides subsp. mesenteroides (strain ATCC 8293
/NCDO 523)
Length = 288
Score = 61.3 bits (142), Expect = 2e-08
Identities = 28/59 (47%), Positives = 37/59 (62%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431
+ V + VV RE++F+TTKLW ++ AI+DSLKKLG DY DL L+H P G
Sbjct: 56 QGVNEAIANAVVAREELFLTTKLWLSEFSYEAAKGAIDDSLKKLGTDYADLILLHQPYG 114
Score = 38.7 bits (86), Expect = 0.14
Identities = 21/60 (35%), Positives = 31/60 (51%)
Frame = +1
Query: 79 MNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
+NNG MP +G G + + ++ + V+ AI+ GYR DTA VY E E G+
Sbjct: 6 LNNGAQMPQLGFGVF---------QIPAEETKQAVVDAINAGYRSIDTARVYGNEAETGQ 56
>UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1;
Orconectes limosus|Rep: Aldoketoreductase-like protein -
Orconectes limosus (Spinycheek crayfish)
Length = 336
Score = 61.3 bits (142), Expect = 2e-08
Identities = 46/157 (29%), Positives = 68/157 (43%), Gaps = 10/157 (6%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG- 431
+ ++ + EG VKRE++FITTKL +R +VA+ + SL L L Y+DLYL+H+P G
Sbjct: 72 QVLRRWISEGKVKREELFITTKLPTRGNREKDVARFLQKSLDNLRLPYVDLYLVHYPCGI 131
Query: 432 -------LNADYSHSD--VDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSN 584
L+AD D D WR +E G K + + K
Sbjct: 132 LDTDRERLSADEVTVDPTTDIHAIWRAMEAQLAAGKTKNIGLSNFNADQVQRIIKGCQVR 191
Query: 585 LMLFK*RVTSKTFQKEMVEFCQSESVVVMGYSPFRFP 695
+ + V Q + FC +VV + P P
Sbjct: 192 PAVLQVEVHVYMQQGALRAFCAQHDIVVCAFCPLGGP 228
Score = 49.6 bits (113), Expect = 7e-05
Identities = 24/66 (36%), Positives = 42/66 (63%)
Frame = +1
Query: 61 EVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240
++P++ +N+G +P +GLGT +NG K ++ + V+ A++ GYRHFD+A+ Y
Sbjct: 10 KIPTILLNSGSHIPVMGLGTG-SLGRNG--KMSEEAVTAVLETALECGYRHFDSAAYYGN 66
Query: 241 EQEIGK 258
E IG+
Sbjct: 67 EAIIGQ 72
>UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 275
Score = 61.3 bits (142), Expect = 2e-08
Identities = 33/137 (24%), Positives = 66/137 (48%)
Frame = +3
Query: 273 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH 452
+ E V R ++++ TK+++T H + +A + SL LG+DY+DLYL+H+P+
Sbjct: 61 LRESAVPRSEVYLVTKVYHTDHGYEKTMKAYDRSLSALGVDYVDLYLIHFPV-------- 112
Query: 453 SDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTSKTFQKE 632
+ +W + + Q G ++ K ++ ++ + V +E
Sbjct: 113 -PAGVVGSWEAMAELQGKGLTRSIGVSNFNIHHLEALQKHSVIPPVVNQIEVHPYLQMEE 171
Query: 633 MVEFCQSESVVVMGYSP 683
+V+FC+ S+ + YSP
Sbjct: 172 LVDFCRKHSIAIQAYSP 188
Score = 35.1 bits (77), Expect = 1.7
Identities = 17/47 (36%), Positives = 22/47 (46%)
Frame = +2
Query: 470 GDLARIGRCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
G + G+ + IG+SNFN LE + K I P QIE H
Sbjct: 118 GSWEAMAELQGKGLTRSIGVSNFNIHHLEALQKHSVIPPVVNQIEVH 164
Score = 33.9 bits (74), Expect = 3.9
Identities = 18/60 (30%), Positives = 31/60 (51%)
Frame = +1
Query: 79 MNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
+++G +P GLG Y +K + V+ A++ GYR DTA+ Y E+ +G+
Sbjct: 9 LSDGYKIPRFGLGLY---------DLDEKHTKQAVLWALENGYRMIDTAASYNNEKRVGE 59
>UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Sulfolobaceae|Rep: Oxidoreductase,
aldo/keto reductase family - Sulfolobus solfataricus
Length = 265
Score = 61.3 bits (142), Expect = 2e-08
Identities = 38/133 (28%), Positives = 66/133 (49%), Gaps = 3/133 (2%)
Frame = +3
Query: 294 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFME 473
R+ IFI TK+W+ + ++ ++ +SLK+L YIDLYL+HWP +S V E
Sbjct: 72 RDKIFIITKVWSNHLKYDDLIRSAKNSLKRLNAKYIDLYLIHWP--------NSSVPLEE 123
Query: 474 TWRGLEDAQRMG*LK---ASDCLTSTSSSWRGC*KKALSNLMLFK*RVTSKTFQKEMVEF 644
+ R +E+ G + S+ KK + V +K+ +K+++ F
Sbjct: 124 SLRAMEELVDQGIVNCIGVSNFDIKLLEETMSITKKYEITANEIEYNVENKSAEKDVIPF 183
Query: 645 CQSESVVVMGYSP 683
C+ ++ V+ YSP
Sbjct: 184 CERNNIKVIAYSP 196
>UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA15457-PA - Nasonia vitripennis
Length = 388
Score = 60.9 bits (141), Expect = 3e-08
Identities = 42/143 (29%), Positives = 65/143 (45%), Gaps = 12/143 (8%)
Frame = +3
Query: 291 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHS----- 455
KREDIFIT+KL + +R V + SLK LGLDY+D+YL+H P + + S
Sbjct: 89 KREDIFITSKLPSQGNRPQSVETYLKRSLKDLGLDYVDMYLIHTPFAVKEGENLSSKQDK 148
Query: 456 -------DVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTS 614
DVD W+ +E + G K+ S A + +
Sbjct: 149 DGNDLFDDVDHKALWKAMERQVKEGRAKSIGLSNFNQSQVLNIYNNAEIKPSNLQVETHA 208
Query: 615 KTFQKEMVEFCQSESVVVMGYSP 683
QK++ +FC+ ++V+ Y+P
Sbjct: 209 YLQQKQLRKFCKEHNIVMTAYAP 231
Score = 44.0 bits (99), Expect = 0.004
Identities = 24/65 (36%), Positives = 37/65 (56%)
Frame = +1
Query: 64 VPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243
V LK+++G +PA+GLGT +K + + + + A++ GYRH DTA Y+ E
Sbjct: 23 VEKLKLSSGHEIPAVGLGT-------STIKLDE--MDNAISSALENGYRHIDTAFSYDNE 73
Query: 244 QEIGK 258
IGK
Sbjct: 74 AAIGK 78
>UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 274
Score = 60.9 bits (141), Expect = 3e-08
Identities = 42/151 (27%), Positives = 73/151 (48%), Gaps = 2/151 (1%)
Frame = +3
Query: 261 VKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA 440
V + ++ V RED+F+TTKL + V ++ +SL KLG DY+DL L+HWP N
Sbjct: 53 VGLGMDAAAVDREDVFLTTKLDGSNRDERSVRRSTRESLNKLGTDYLDLLLIHWP---NT 109
Query: 441 DYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTSKT 620
+ S ET + D G ++ + S + +S+ +F +V
Sbjct: 110 PWMAS---LSETLGAMNDVVEEGLVRHIGVSNFSPSLLDRA--RDISSAPIFTDQVQYHP 164
Query: 621 F--QKEMVEFCQSESVVVMGYSPFRFPGXPD 707
+ Q++++++C+ V++ YSP G D
Sbjct: 165 YWDQRKLLDYCRIHDVLLTAYSPLARGGVLD 195
Score = 39.5 bits (88), Expect = 0.079
Identities = 20/56 (35%), Positives = 31/56 (55%)
Frame = +1
Query: 88 GRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
G +PA+GLGT+ + + R+ V A+ +GYRH DTA Y E+++G
Sbjct: 8 GTSVPALGLGTW---------QLTGQSCRETVETALGMGYRHIDTAQAYGNERQVG 54
>UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2;
Schizosaccharomyces pombe|Rep: Probable oxidoreductase
C26F1.07 - Schizosaccharomyces pombe (Fission yeast)
Length = 321
Score = 60.9 bits (141), Expect = 3e-08
Identities = 43/149 (28%), Positives = 66/149 (44%), Gaps = 11/149 (7%)
Frame = +3
Query: 273 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA--DY 446
++E V R+DI++T+KLW H V +A+ +LK L LDY+D YL+HWP+ D
Sbjct: 70 IKESGVPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGEDK 129
Query: 447 SHSDVD---------FMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK 599
D D ETW+ +E G ++ ++ K A + +
Sbjct: 130 FPKDKDGNLIYEKNPIEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAKVKPAVHQ 189
Query: 600 *RVTSKTFQKEMVEFCQSESVVVMGYSPF 686
+ Q E VE + + V YSPF
Sbjct: 190 MELHPFLPQTEFVEKHKKLGIHVTAYSPF 218
Score = 42.3 bits (95), Expect = 0.011
Identities = 20/57 (35%), Positives = 32/57 (56%)
Frame = +1
Query: 85 NGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
+G +P +GLGT+ +S+ Q ++ V A+ GYRH D A++Y E E+G
Sbjct: 20 DGSKIPGLGLGTW---------RSEPNQTKNAVKTALQYGYRHIDAAAIYGNEDEVG 67
>UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=2; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
Length = 273
Score = 60.5 bits (140), Expect = 4e-08
Identities = 41/137 (29%), Positives = 68/137 (49%)
Frame = +3
Query: 273 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH 452
V+ + R+++FITTK + T++ +++SL+++GLDY DL L+HWP+G
Sbjct: 58 VKASGLNRDEVFITTKTMTDGYEDTKIG--LDESLRRIGLDYFDLVLIHWPMG------- 108
Query: 453 SDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTSKTFQKE 632
D+D TW LE A + G +A S ++ M+ + Q +
Sbjct: 109 HDID---TWHALEAAYKAGKTRAIGISNFNSRQTLDLIHQSSVRPMVDQIETHLFLQQWK 165
Query: 633 MVEFCQSESVVVMGYSP 683
M EF + E++V YSP
Sbjct: 166 MHEFLEKENIVHESYSP 182
Score = 39.5 bits (88), Expect = 0.079
Identities = 21/62 (33%), Positives = 31/62 (50%)
Frame = +1
Query: 73 LKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252
L +NN +P G GTY + Q + V+ A + GYR DTA Y+ EQ++
Sbjct: 4 LTLNNDVKIPIFGFGTY---------EISPDQTKQAVLSAFEEGYRLIDTAQYYQNEQQV 54
Query: 253 GK 258
G+
Sbjct: 55 GE 56
>UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3;
Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis
alexandrii HTCC2633
Length = 275
Score = 60.5 bits (140), Expect = 4e-08
Identities = 23/47 (48%), Positives = 34/47 (72%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428
VKRED F+TTK+W + R ++ ++ +SL KL DY+DL L+HWP+
Sbjct: 63 VKREDFFLTTKVWRDKFRDGDLQASVKESLDKLKTDYVDLLLLHWPV 109
Score = 35.9 bits (79), Expect = 0.98
Identities = 19/57 (33%), Positives = 28/57 (49%)
Frame = +1
Query: 85 NGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
NG +P +G GT+ + +D+ V A+ GYRH DTA +Y E +G
Sbjct: 8 NGADIPKLGFGTW---------QLEDEDAARGVATALKTGYRHIDTAQIYGNEAAVG 55
>UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2;
Corynebacterium|Rep: Putative oxidoreductase -
Corynebacterium diphtheriae
Length = 290
Score = 60.1 bits (139), Expect = 5e-08
Identities = 25/56 (44%), Positives = 36/56 (64%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425
AV + G V R+++FITTK+WN H ++ +SL +LGLDYID ++HWP
Sbjct: 67 AVADAITAGEVARDELFITTKVWNDMHGDQLTQRSFQESLHRLGLDYIDCCMVHWP 122
Score = 59.7 bits (138), Expect = 7e-08
Identities = 28/65 (43%), Positives = 42/65 (64%)
Frame = +1
Query: 64 VPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243
+P++ +N+G MPAIG GTY K +++ V AI+VGYRH DTAS+Y+ E
Sbjct: 11 IPTITLNDGTEMPAIGFGTY---------KLREQDAYRAVRSAIEVGYRHIDTASLYKNE 61
Query: 244 QEIGK 258
+E+G+
Sbjct: 62 EEVGR 66
>UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 339
Score = 60.1 bits (139), Expect = 5e-08
Identities = 28/65 (43%), Positives = 42/65 (64%)
Frame = +1
Query: 64 VPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243
+PS +N G +P++G+G + G Q G +D +L D ++RAI VGYRH DTA+ Y E
Sbjct: 5 IPSFTLNTGAKLPSVGMGCWQG--QPG--PGRDNELVDALVRAIKVGYRHLDTATGYRNE 60
Query: 244 QEIGK 258
E+G+
Sbjct: 61 AEVGQ 65
Score = 58.0 bits (134), Expect = 2e-07
Identities = 46/158 (29%), Positives = 70/158 (44%), Gaps = 17/158 (10%)
Frame = +3
Query: 261 VKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA 440
V V + V R +IF+TTKL +V Q + +SL +LG+DYIDL+L+HWP G
Sbjct: 63 VGQAVRQSGVARSEIFVTTKL--RPGGVHDVVQELENSLNELGIDYIDLWLLHWPQGFTK 120
Query: 441 D--------------YSHSDVDFMETWRGLEDA---QRMG*LKASDCLTSTSSSWRGC*K 569
D H F ETW +ED G +KA + + K
Sbjct: 121 DDGGFGTGESFGLEHQKHLGPTFNETWAKMEDVFLNSHKGKVKAIGVSNFSIKNLEILAK 180
Query: 570 KALSNLMLFK*RVTSKTFQKEMVEFCQSESVVVMGYSP 683
+ + + + E+V++C+ +S+ V YSP
Sbjct: 181 TSKVTPAVNQIEAHPYLPEHELVKYCKHKSIHVTAYSP 218
Score = 34.3 bits (75), Expect = 3.0
Identities = 17/38 (44%), Positives = 22/38 (57%)
Frame = +2
Query: 497 SANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
S G VK IG+SNF+ + LE + K + P QIE H
Sbjct: 157 SHKGKVKAIGVSNFSIKNLEILAKTSKVTPAVNQIEAH 194
>UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase;
n=1; Rhodococcus sp. RHA1|Rep: Probable
2,5-didehydrogluconate reductase - Rhodococcus sp.
(strain RHA1)
Length = 265
Score = 59.7 bits (138), Expect = 7e-08
Identities = 26/58 (44%), Positives = 40/58 (68%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428
+AV + + E V RE++F+TTKL + H ++ A+ SLK LGLD +DL+L+HWP+
Sbjct: 44 DAVGVALAECGVPREELFVTTKLRGSDHVSGDIRGAVERSLKNLGLDRLDLFLIHWPL 101
>UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep:
CG2767-PA - Drosophila melanogaster (Fruit fly)
Length = 329
Score = 59.7 bits (138), Expect = 7e-08
Identities = 48/159 (30%), Positives = 75/159 (47%), Gaps = 13/159 (8%)
Frame = +3
Query: 261 VKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP--IGL 434
+K ++ G VKRE++FI TK+ +R EV I SL+ L LDY+DLYL+H P I +
Sbjct: 61 LKRWLDAGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTINI 120
Query: 435 NADYSHS-------DVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLML 593
N D S +VD + A K S+ + + L N +
Sbjct: 121 NEDGSFKLDKEGLMEVDVTTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLLKNCKI 180
Query: 594 --FK*RVTSKTF--QKEMVEFCQSESVVVMGYSPFRFPG 698
++ + Q+++V+FC+SE++ V YSP G
Sbjct: 181 RPANNQIEHHVYLQQRDLVDFCKSENITVTAYSPLGSKG 219
Score = 50.4 bits (115), Expect = 4e-05
Identities = 24/62 (38%), Positives = 36/62 (58%)
Frame = +1
Query: 73 LKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252
L NNG MP IG+GT+ ++ D+++ + A++ GYRH DTA VY E+ I
Sbjct: 7 LTFNNGEKMPVIGIGTW---------QASDEEIETAIDAALEAGYRHIDTAPVYGNEKAI 57
Query: 253 GK 258
G+
Sbjct: 58 GR 59
Score = 39.9 bits (89), Expect = 0.060
Identities = 18/36 (50%), Positives = 25/36 (69%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGHL 613
G+ K IG+SNF+K Q+ R+LK I+P QIE H+
Sbjct: 156 GLTKSIGVSNFSKDQVARLLKNCKIRPANNQIEHHV 191
>UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5;
Trypanosomatidae|Rep: Aldo-keto reductase-like protein -
Leishmania major strain Friedlin
Length = 372
Score = 59.7 bits (138), Expect = 7e-08
Identities = 25/58 (43%), Positives = 35/58 (60%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428
EA+ + +RED+F+T+KLW T V A +L L LDY+DLYL+HWP+
Sbjct: 74 EALAQALRTRCTRREDLFVTSKLWPTDQHPDHVEAACRATLAALQLDYLDLYLIHWPV 131
Score = 32.7 bits (71), Expect = 9.1
Identities = 18/62 (29%), Positives = 27/62 (43%)
Frame = +1
Query: 73 LKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252
+ M + +P +G GTY + + D V A+ GYRH D A Y E +
Sbjct: 22 IAMRDSHTIPQLGFGTY---------RLPVSEATDAVAFALSCGYRHVDCAKAYGNEAAV 72
Query: 253 GK 258
G+
Sbjct: 73 GE 74
>UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 -
Trichoderma atroviride (Hypocrea atroviridis)
Length = 327
Score = 59.7 bits (138), Expect = 7e-08
Identities = 44/147 (29%), Positives = 68/147 (46%), Gaps = 15/147 (10%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL--NADYS---H 452
V R+D+FI TK+WN H +V + +S + L +DYIDL+L+HWPI NAD +
Sbjct: 81 VTRKDLFICTKVWNHLHEPEDVKWSAKNSCENLKVDYIDLFLVHWPIAAEKNADRTVKIG 140
Query: 453 SDVDFM----------ETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK* 602
D ++ TWR +E+ G +KA T + + A + +
Sbjct: 141 PDGKYVINKALTENPEPTWRAMEELVDSGIVKAIGVSNWTIPGLKQLLEFARIKPAVNQI 200
Query: 603 RVTSKTFQKEMVEFCQSESVVVMGYSP 683
+ E+VEFC ++ YSP
Sbjct: 201 EIHPFLPNTELVEFCFQNDILPEAYSP 227
Score = 44.0 bits (99), Expect = 0.004
Identities = 23/67 (34%), Positives = 33/67 (49%)
Frame = +1
Query: 55 TMEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY 234
T+ + +N G +PA+G GT+ G + V +A+DVGYRH D A Y
Sbjct: 9 TLSSTTYTLNTGAKIPAVGFGTFANEGAKGETYA-------AVTKALDVGYRHLDCAWFY 61
Query: 235 ETEQEIG 255
E E+G
Sbjct: 62 LNEDEVG 68
Score = 33.5 bits (73), Expect = 5.2
Identities = 17/36 (47%), Positives = 24/36 (66%)
Frame = +2
Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
+GIVK IG+SN+ L+++L+ IKP QIE H
Sbjct: 168 SGIVKAIGVSNWTIPGLKQLLEFARIKPAVNQIEIH 203
>UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Acinetobacter sp. (strain ADP1)
Length = 297
Score = 59.3 bits (137), Expect = 9e-08
Identities = 31/88 (35%), Positives = 49/88 (55%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437
AV V + + R++IFIT+KL H + + I +SL ++ DY+DLYL+HWP
Sbjct: 74 AVGAAVRQSGLLRDEIFITSKLPGRHHAYDKAMETIEESLYRMQFDYLDLYLIHWPNPQQ 133
Query: 438 ADYSHSDVDFMETWRGLEDAQRMG*LKA 521
Y +E W+ L DAQ+ G +++
Sbjct: 134 GLY-------IEAWQALIDAQKKGYIRS 154
Score = 43.6 bits (98), Expect = 0.005
Identities = 24/64 (37%), Positives = 35/64 (54%)
Frame = +1
Query: 64 VPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243
+P L +++G +PA+G GTY Q GV D ++RA+ GYR D+A YE E
Sbjct: 22 IPDLILHDGHSIPALGFGTYTLKGQQGV---------DTMLRALGHGYRMLDSAFNYENE 72
Query: 244 QEIG 255
+G
Sbjct: 73 GAVG 76
>UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia
ATCC 50803
Length = 313
Score = 59.3 bits (137), Expect = 9e-08
Identities = 22/47 (46%), Positives = 34/47 (72%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428
+KRED++IT+KLWN HR V + ++ L +DY+DL+L+HWP+
Sbjct: 61 IKREDVWITSKLWNYNHRPELVREQCKKTMSDLQVDYLDLFLVHWPL 107
Score = 33.5 bits (73), Expect = 5.2
Identities = 17/45 (37%), Positives = 26/45 (57%)
Frame = +1
Query: 124 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
LGF G ++ + ++ V A+ GYRH D A VY+ E+ IG+
Sbjct: 7 LGF---GTWQAPPEAVQTAVETALMTGYRHIDCAYVYQNEEAIGR 48
>UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase B - Corynebacterium sp. (strain SHS752001)
Length = 277
Score = 59.3 bits (137), Expect = 9e-08
Identities = 30/79 (37%), Positives = 45/79 (56%)
Frame = +3
Query: 273 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH 452
V V R+++ + +K+ QH R E +I SL +LGLD IDL L+HWP +
Sbjct: 61 VRASSVDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHWP-------NP 113
Query: 453 SDVDFMETWRGLEDAQRMG 509
S +++TWRG+ DA+ G
Sbjct: 114 SVGRWLDTWRGMIDAREAG 132
Score = 43.6 bits (98), Expect = 0.005
Identities = 25/65 (38%), Positives = 34/65 (52%)
Frame = +1
Query: 64 VPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243
+P++ +N+GR GLGTY GV ++ AID GYR DTA YE E
Sbjct: 4 IPTISLNDGRPFAEPGLGTYNLRGDEGVA---------AMVAAIDSGYRLLDTAVNYENE 54
Query: 244 QEIGK 258
E+G+
Sbjct: 55 SEVGR 59
>UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose
reductase - Hordeum vulgare (Barley)
Length = 320
Score = 59.3 bits (137), Expect = 9e-08
Identities = 41/151 (27%), Positives = 70/151 (46%), Gaps = 8/151 (5%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
+ +K +E G+ R+D+F+T+K+W T V A+ ++LK L LDYIDLY +HWP L
Sbjct: 68 KGLKAAMEAGI-DRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRL 126
Query: 435 NADYSHS--------DVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLM 590
D +H + D W+ +E+ + G +K T + + A
Sbjct: 127 K-DGAHMPPEAGEVLEFDMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAKIPPA 185
Query: 591 LFK*RVTSKTFQKEMVEFCQSESVVVMGYSP 683
+ + + ++ E C+ + V YSP
Sbjct: 186 VCQMEMHPGWKNDKIFEACKKHGIHVTAYSP 216
Score = 39.9 bits (89), Expect = 0.060
Identities = 21/60 (35%), Positives = 31/60 (51%)
Frame = +1
Query: 79 MNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
+ +G MPA+GLGT+ ++ V + GYRH DTA+ Y E+E+GK
Sbjct: 18 LKSGHAMPAVGLGTW---------RAGSDTAHSVRTAITEAGYRHVDTAAEYGVEKEVGK 68
>UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1;
Clostridium beijerinckii NCIMB 8052|Rep:
2,5-didehydrogluconate reductase - Clostridium
beijerinckii NCIMB 8052
Length = 289
Score = 58.8 bits (136), Expect = 1e-07
Identities = 27/84 (32%), Positives = 48/84 (57%)
Frame = +3
Query: 267 MKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADY 446
+ +E+ + RE+ FIT+K+WNT H +A + KKL ++Y+D+YL+H+ + Y
Sbjct: 61 LAIEKSQIPREEFFITSKVWNTDHGYEATKKAFEQTCKKLNVEYLDMYLIHFA----SSY 116
Query: 447 SHSDVDFMETWRGLEDAQRMG*LK 518
++ETW +E+ G +K
Sbjct: 117 ------YLETWHAMEELYLQGKIK 134
Score = 43.6 bits (98), Expect = 0.005
Identities = 22/61 (36%), Positives = 32/61 (52%)
Frame = +1
Query: 73 LKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252
+K NG +P +G G Y +K + V AI +GYRHFDTA +Y E+++
Sbjct: 8 IKAVNGIKIPQVGFGVYK--------LNKGEDFETAVGEAIKIGYRHFDTAKIYGNEKDL 59
Query: 253 G 255
G
Sbjct: 60 G 60
Score = 33.5 bits (73), Expect = 5.2
Identities = 16/35 (45%), Positives = 21/35 (60%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
G +K IG++NF Q LE ++K I P QIE H
Sbjct: 131 GKIKVIGVANFQIQHLEELMKHSRITPMINQIETH 165
>UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 284
Score = 58.8 bits (136), Expect = 1e-07
Identities = 28/66 (42%), Positives = 40/66 (60%)
Frame = +1
Query: 61 EVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240
+ P +K+NNG MP +GLGT+L + GV + + AID GYRH DTA Y+
Sbjct: 4 KAPMVKLNNGLEMPVLGLGTWLSKEGEGV---------EAIKAAIDAGYRHIDTAYFYQN 54
Query: 241 EQEIGK 258
E+E+G+
Sbjct: 55 EKEVGE 60
Score = 46.4 bits (105), Expect = 7e-04
Identities = 37/147 (25%), Positives = 63/147 (42%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
EA++ K+EEGVV RED+F+TTK +D+ LM P
Sbjct: 60 EAIRAKIEEGVVCREDLFVTTKF----------------------IDWDTKNLM--PYDA 95
Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTS 614
+ SDVD+++TW+ +E + G +K+ S + + +
Sbjct: 96 DGKLQFSDVDYIDTWKAMEKLLKTGKVKSIGVSNFNSEQITRLLAECEIKPVTNQVECNP 155
Query: 615 KTFQKEMVEFCQSESVVVMGYSPFRFP 695
Q+++ EFC++ + + YSP P
Sbjct: 156 SLNQRKLTEFCKNLDITLTAYSPLGRP 182
Score = 38.7 bits (86), Expect = 0.14
Identities = 18/33 (54%), Positives = 23/33 (69%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIE 604
G VK IG+SNFN +Q+ R+L E IKP Q+E
Sbjct: 120 GKVKSIGVSNFNSEQITRLLAECEIKPVTNQVE 152
>UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Opitutaceae bacterium TAV2
Length = 334
Score = 58.4 bits (135), Expect = 2e-07
Identities = 22/58 (37%), Positives = 38/58 (65%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428
E V + + R++++ITTK+WN+ +A+ +SL +L L+Y+DLYL+HWP+
Sbjct: 110 EGVGRAIRASGLPRKELYITTKVWNSAQGYDSTLRAVRESLGRLQLEYVDLYLIHWPV 167
Score = 36.3 bits (80), Expect = 0.74
Identities = 19/65 (29%), Positives = 33/65 (50%)
Frame = +1
Query: 64 VPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243
+P+L +++G +P +GLG + D V + A + GYR DTA +Y E
Sbjct: 59 IPTLPLSDGTSIPQLGLGVWQMPDDGAGVP---------IQAAFNAGYRAIDTAPIYGNE 109
Query: 244 QEIGK 258
+ +G+
Sbjct: 110 EGVGR 114
Score = 33.5 bits (73), Expect = 5.2
Identities = 15/42 (35%), Positives = 24/42 (57%)
Frame = +2
Query: 485 IGRCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
+ + A+G+ + IG+SNF L+R+ E I P Q+E H
Sbjct: 180 LAKIKADGLARSIGVSNFTPVYLQRLFDETGIVPVVNQVELH 221
>UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus
niger|Rep: Putative frameshift - Aspergillus niger
Length = 357
Score = 58.4 bits (135), Expect = 2e-07
Identities = 31/94 (32%), Positives = 49/94 (52%), Gaps = 11/94 (11%)
Frame = +3
Query: 273 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYS- 449
+++ V RE+IF+ TKLW +V +A++DSL+ L Y+DL LMH+P
Sbjct: 91 IKKSGVPREEIFLGTKLWCNDFHPDDVERAVDDSLRDLYTPYVDLLLMHYPCTFKRGEDR 150
Query: 450 ----------HSDVDFMETWRGLEDAQRMG*LKA 521
H + F++TWR LE + G ++A
Sbjct: 151 FPRDAEGRMIHGETTFVDTWRALEKVVKTGKVRA 184
Score = 35.5 bits (78), Expect = 1.3
Identities = 20/60 (33%), Positives = 32/60 (53%)
Frame = +1
Query: 79 MNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
+N G +PA+G+GT+ + D Q + V + + G R DTA VY EQ++G+
Sbjct: 40 LNTGAKIPALGVGTF---------QDPDSQ-EETVCQVLQRGMRLIDTARVYGVEQQVGR 89
>UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5;
Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas
putida
Length = 296
Score = 58.4 bits (135), Expect = 2e-07
Identities = 23/46 (50%), Positives = 34/46 (73%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425
V R ++F+TTKL+N + +A ++SL +LGLDY+DLYL+HWP
Sbjct: 67 VDRAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLHWP 112
Score = 39.9 bits (89), Expect = 0.060
Identities = 21/64 (32%), Positives = 32/64 (50%)
Frame = +1
Query: 67 PSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 246
P + +NNG MPA+GLG + + ++ + AI GYR DTA Y E
Sbjct: 6 PLINLNNGVKMPALGLGVFA---------ASAEETASAIASAISSGYRLIDTARSYNNEA 56
Query: 247 EIGK 258
++G+
Sbjct: 57 QVGE 60
>UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
2,5-diketo-D-gluconic acid reductase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 159
Score = 58.0 bits (134), Expect = 2e-07
Identities = 22/44 (50%), Positives = 32/44 (72%)
Frame = +3
Query: 294 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425
R+++F+TTKLWN +A + SL+ LGLD++DLYL+HWP
Sbjct: 68 RDELFVTTKLWNADQGYDNALRAFDTSLELLGLDHLDLYLIHWP 111
Score = 38.3 bits (85), Expect = 0.18
Identities = 20/65 (30%), Positives = 33/65 (50%)
Frame = +1
Query: 64 VPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243
VP++ +NNG MP +G G + + + + V A++ GYR DTA+ Y E
Sbjct: 4 VPTVTLNNGVEMPQLGYGVF---------QVPEDETAAAVGAALEAGYRSIDTAAAYGNE 54
Query: 244 QEIGK 258
+G+
Sbjct: 55 AAVGR 59
>UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;
Corynebacterineae|Rep: 2,5-didehydrogluconate reductase
- Mycobacterium sp. (strain KMS)
Length = 283
Score = 58.0 bits (134), Expect = 2e-07
Identities = 32/84 (38%), Positives = 46/84 (54%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437
AV V + RE+I++TTKL A SL++LGLDY+DLYL+HWP G +
Sbjct: 63 AVGRAVNASGIPREEIYVTTKLAVADQGFGTSQDAARASLERLGLDYVDLYLIHWPAGDH 122
Query: 438 ADYSHSDVDFMETWRGLEDAQRMG 509
Y +++W GL A++ G
Sbjct: 123 GKY-------IDSWGGLMKAKQDG 139
Score = 40.3 bits (90), Expect = 0.045
Identities = 21/65 (32%), Positives = 35/65 (53%)
Frame = +1
Query: 64 VPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243
+PS+ +N+G +P +GLG V + + + V A++ GYR DTA+VY E
Sbjct: 11 IPSVSLNDGHSIPVLGLG---------VGELSEAEAERSVAAALEAGYRLIDTAAVYGNE 61
Query: 244 QEIGK 258
+G+
Sbjct: 62 AAVGR 66
>UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1;
Griffithsia japonica|Rep: Mannose 6-phosphate reductase
- Griffithsia japonica (Red alga)
Length = 174
Score = 58.0 bits (134), Expect = 2e-07
Identities = 29/64 (45%), Positives = 42/64 (65%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437
A+ + GVVKRED+FIT+K+WNT H +V + SLK +DY DL+L+ IG+
Sbjct: 59 AISKAISGGVVKREDLFITSKVWNTCHATDKVVDSCRQSLKDHQVDYFDLFLVR-DIGV- 116
Query: 438 ADYS 449
++YS
Sbjct: 117 SNYS 120
Score = 34.7 bits (76), Expect = 2.3
Identities = 20/66 (30%), Positives = 30/66 (45%)
Frame = +1
Query: 58 MEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237
M + + +G MP G GT+ K+ ++ V A+ GYRH D A+VY
Sbjct: 1 MSTNTATLQSGAKMPLNGFGTW---------KASVEETEQAVTAALRAGYRHIDCAAVYW 51
Query: 238 TEQEIG 255
E +G
Sbjct: 52 NEAAVG 57
>UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2;
Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid
reductase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 283
Score = 57.6 bits (133), Expect = 3e-07
Identities = 24/46 (52%), Positives = 32/46 (69%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425
+KRE+ F+TTKLWN+ + +A SL L LDY+DLYL+HWP
Sbjct: 71 IKREEFFVTTKLWNSDQPKPR--EAFERSLDLLSLDYVDLYLIHWP 114
Score = 50.8 bits (116), Expect = 3e-05
Identities = 26/65 (40%), Positives = 38/65 (58%)
Frame = +1
Query: 64 VPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243
VPS+ + +G +P GLGTY + + VV AI++GYRH DTAS+Y E
Sbjct: 9 VPSVLLGDGVSIPQFGLGTY---------ELPPNEASSVVQSAIELGYRHIDTASLYANE 59
Query: 244 QEIGK 258
+E+G+
Sbjct: 60 REVGR 64
>UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4;
Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia
sp. (strain CCS1)
Length = 276
Score = 57.6 bits (133), Expect = 3e-07
Identities = 23/76 (30%), Positives = 47/76 (61%)
Frame = +3
Query: 294 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFME 473
R+++F+TTK+WN + + ++ SLK +G++ +DL L+HWP+ D+ ++E
Sbjct: 68 RDEVFVTTKVWNNEQGAAKARASVERSLKTIGVEQLDLVLIHWPV------PSQDL-YLE 120
Query: 474 TWRGLEDAQRMG*LKA 521
TW+ +D + G +++
Sbjct: 121 TWKAFQDMRDEGLMRS 136
>UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 292
Score = 57.6 bits (133), Expect = 3e-07
Identities = 34/83 (40%), Positives = 44/83 (53%)
Frame = +3
Query: 273 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH 452
+E + RED+FITTK+ N+ H A +I SL+ L DY+DL L+HWP L Y
Sbjct: 73 LEASGIAREDLFITTKVDNSNHEPDRAAASIRRSLEDLRTDYVDLLLVHWP--LPTLYGG 130
Query: 453 SDVDFMETWRGLEDAQRMG*LKA 521
D W LEDA G +A
Sbjct: 131 ---DVALPWPALEDAFNAGGARA 150
Score = 48.8 bits (111), Expect = 1e-04
Identities = 24/64 (37%), Positives = 34/64 (53%)
Frame = +1
Query: 64 VPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243
+P+ + G +P +G GTY K + D V RA++VGYRH DTA +Y E
Sbjct: 16 IPTFMLPTGSPIPVLGFGTY---------KVAPEDTYDAVSRALEVGYRHIDTAQMYGNE 66
Query: 244 QEIG 255
E+G
Sbjct: 67 AEVG 70
Score = 35.1 bits (77), Expect = 1.7
Identities = 13/35 (37%), Positives = 22/35 (62%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
G + IGLSN+ ++ +E V + T+ P +Q+E H
Sbjct: 146 GGARAIGLSNYEREHVEAVREVATVAPHVLQVESH 180
>UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15;
Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B -
Bradyrhizobium sp. (strain ORS278)
Length = 273
Score = 57.6 bits (133), Expect = 3e-07
Identities = 25/62 (40%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP-IG 431
+A+ + + RED+ +TTK+W + +A + SLKKL LD++DLYL+HWP G
Sbjct: 51 DAIGAALAAAQIAREDLHVTTKVWPENLAPDAIRRAFDTSLKKLRLDFVDLYLIHWPATG 110
Query: 432 LN 437
+N
Sbjct: 111 MN 112
Score = 39.9 bits (89), Expect = 0.060
Identities = 24/56 (42%), Positives = 29/56 (51%)
Frame = +1
Query: 88 GRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
G +P +GLGT F G V RD V A+ +GYRH DTA +Y E IG
Sbjct: 8 GVRLPKLGLGT---FRMQGTV------CRDAVESALALGYRHIDTAEMYANEDAIG 54
>UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep:
Oxidoreductase - Xanthomonas campestris pv. campestris
(strain 8004)
Length = 267
Score = 57.2 bits (132), Expect = 4e-07
Identities = 22/55 (40%), Positives = 36/55 (65%)
Frame = +3
Query: 261 VKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425
V + + V R+ +F+TTK+W + R + ++ +SL+KLG DY+DL L+HWP
Sbjct: 45 VGQAIADAGVPRDQLFVTTKIWVDRFSRDTLQPSLQESLRKLGTDYVDLTLIHWP 99
Score = 39.5 bits (88), Expect = 0.079
Identities = 20/54 (37%), Positives = 32/54 (59%)
Frame = +1
Query: 97 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
+PA GLGT+ + KD+ + D V A+ +GYR DTA +Y+ E ++G+
Sbjct: 3 VPAFGLGTF---------RLKDQVVIDSVRNALALGYRAIDTAQIYDNEAQVGQ 47
>UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis
vadensis ATCC BAA-548|Rep: Aldo/keto reductase -
Victivallis vadensis ATCC BAA-548
Length = 287
Score = 57.2 bits (132), Expect = 4e-07
Identities = 40/149 (26%), Positives = 75/149 (50%), Gaps = 4/149 (2%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
E V + ++ ++R D F+T K+W T R +V +A SLK+LG DYIDLYL+H
Sbjct: 67 ELVGIAMKGQGIRRADYFLTDKVWKTHLRYDDVLRAAEASLKRLGTDYIDLYLIH----- 121
Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKA----LSNLMLFK* 602
+ DV ET R + +R G ++ + + + ++N + +
Sbjct: 122 ---QVNPDVPEEETIRAMNRLKREGVIRHIGVSNFSEERLKRAQAASDAPIVANQLHYNL 178
Query: 603 RVTSKTFQKEMVEFCQSESVVVMGYSPFR 689
R+ + Q ++++C+S+ ++V+ + P R
Sbjct: 179 RI-REIEQCGLLDYCRSQDIMVIAWRPLR 206
>UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Shewanella sp. (strain ANA-3)
Length = 280
Score = 57.2 bits (132), Expect = 4e-07
Identities = 39/149 (26%), Positives = 73/149 (48%), Gaps = 3/149 (2%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
+AV + + RE++FITTK+W + ++ DSL L Y+DL L+HWP L
Sbjct: 57 QAVGDAINTSGIPREELFITTKVWTENLTKERFETSVIDSLTALQTKYLDLLLIHWP--L 114
Query: 435 NADYSHSDVDFMETWRGLED---AQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*R 605
N+D S V+++ + + D +R+G ++ + + + G + +
Sbjct: 115 NSD-EPSMVEYLSELKAVLDKGLTRRIGVSNFTNAQLAQAIAILG-----EGVIYTNQVE 168
Query: 606 VTSKTFQKEMVEFCQSESVVVMGYSPFRF 692
V +++ +FC+ +V+V GY PF +
Sbjct: 169 VHPYLINRKVTDFCRQHNVLVTGYMPFAY 197
Score = 38.7 bits (86), Expect = 0.14
Identities = 16/38 (42%), Positives = 22/38 (57%)
Frame = +1
Query: 142 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
G + KD D V+ A++ G RH DTA +Y EQ +G
Sbjct: 23 GTFRLKDNAAFDAVLMALEEGSRHIDTAQIYGNEQAVG 60
>UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4;
Bifidobacterium|Rep: Dehydrogenase or reductase protein
- Bifidobacterium longum
Length = 289
Score = 56.8 bits (131), Expect = 5e-07
Identities = 35/131 (26%), Positives = 64/131 (48%)
Frame = +3
Query: 291 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFM 470
KRE +++TTKL ++Q +A ++SLK L LDY+D+Y++HWP D+ +D
Sbjct: 78 KRETLWVTTKLRDSQQGYDSALKAFDNSLKLLQLDYVDMYMIHWPTPF--DWRSTD---- 131
Query: 471 ETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTSKTFQKEMVEFCQ 650
TW+ + G + + + ++ + + + + Q+E+V FC+
Sbjct: 132 -TWKAFVKLRDEGMARTLGVCNFMPADLKRLHEETGAWPAVNQIELHPTWQQREVVAFCK 190
Query: 651 SESVVVMGYSP 683
+ V YSP
Sbjct: 191 EHGIAVEAYSP 201
Score = 42.7 bits (96), Expect = 0.009
Identities = 24/65 (36%), Positives = 34/65 (52%)
Frame = +1
Query: 64 VPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243
VP + + +G +P +GLG L D GVV VV A++ GYRH D A+ Y E
Sbjct: 11 VPDIALKDGHSIPQVGLGV-LRIDDEGVVP--------VVESALEAGYRHIDGAAGYNNE 61
Query: 244 QEIGK 258
+G+
Sbjct: 62 AGVGR 66
>UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8;
Saccharomycetales|Rep: Probable oxidoreductase YJR096W -
Saccharomyces cerevisiae (Baker's yeast)
Length = 282
Score = 56.8 bits (131), Expect = 5e-07
Identities = 41/143 (28%), Positives = 70/143 (48%), Gaps = 7/143 (4%)
Frame = +3
Query: 276 EEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKL-GLDYIDLYLMHWPIGLNADYSH 452
+ G KRE+IF TTKLWN+Q+ AI L ++ GL YIDL L+H P+
Sbjct: 67 DPGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSPL-------E 119
Query: 453 SDVDFMETWRGLEDAQRMG*LKASDCLTSTSS------SWRGC*KKALSNLMLFK*RVTS 614
+ETWR +++A G +K+ +W K + N + ++
Sbjct: 120 GSKLRLETWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWPELKHKPVVNQI----EISP 175
Query: 615 KTFQKEMVEFCQSESVVVMGYSP 683
++E+ ++C+S+ +VV ++P
Sbjct: 176 WIMRQELADYCKSKGLVVEAFAP 198
Score = 46.0 bits (104), Expect = 0.001
Identities = 24/60 (40%), Positives = 36/60 (60%)
Frame = +1
Query: 76 KMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
K++NG +P+I LGTY + +S Q ++V + GYRHFDTA +Y E+E+G
Sbjct: 7 KLSNGFKIPSIALGTY------DIPRS---QTAEIVYEGVKCGYRHFDTAVLYGNEKEVG 57
>UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
CG2767-PA - Nasonia vitripennis
Length = 356
Score = 56.4 bits (130), Expect = 6e-07
Identities = 45/154 (29%), Positives = 68/154 (44%), Gaps = 15/154 (9%)
Frame = +3
Query: 291 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI-----------GLN 437
KRED+FITTKL R V + SL+KLGL+Y+++YL+H P LN
Sbjct: 91 KREDLFITTKLPPIGMRAEYVESYLKLSLEKLGLEYVNMYLIHKPFAFVKDKYKYEPALN 150
Query: 438 ADYS---HSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RV 608
D S +D D + WR +E + G +++ S + A + +
Sbjct: 151 PDGSVVLDTDTDHVAIWRAMEKQVKAGRVRSIGLSNFNKSQLLNVYEHAEIKPSNLQIEL 210
Query: 609 TSKTFQKEMVEFCQSESVVVMGYSPFRFPG-XPD 707
+ Q+ M E C ++ V +S PG PD
Sbjct: 211 QAYNQQRPMRELCAERNITVTAFSTLGSPGSSPD 244
Score = 43.6 bits (98), Expect = 0.005
Identities = 23/63 (36%), Positives = 35/63 (55%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249
++K+++G MP IGLGT+ + + + V A++ GYRH DTA Y E+
Sbjct: 27 TIKLSSGHDMPMIGLGTW---------QMPPEAIEVAVTAALESGYRHIDTAFTYGNEEA 77
Query: 250 IGK 258
IGK
Sbjct: 78 IGK 80
>UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 288
Score = 56.4 bits (130), Expect = 6e-07
Identities = 38/133 (28%), Positives = 60/133 (45%), Gaps = 2/133 (1%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP--IGLNADYSHSDV 461
+ RED+FIT+KL + + ++ SL++LGL YIDLYL+HWP GL +
Sbjct: 72 LSREDVFITSKL-GPKDQGSKARNGCQKSLEQLGLGYIDLYLIHWPGTQGLPVGDKRNPE 130
Query: 462 DFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTSKTFQKEMVE 641
+ ++WR LE+ G +A T + K + + K Q ++
Sbjct: 131 NRAQSWRVLEEFYSEGKFRAIGVSNYTVEHMQELLKSCKVPPAVLQVEFHPKLLQNDLRG 190
Query: 642 FCQSESVVVMGYS 680
C+ V YS
Sbjct: 191 LCKIRGVCFQAYS 203
Score = 41.9 bits (94), Expect = 0.015
Identities = 24/63 (38%), Positives = 32/63 (50%)
Frame = +1
Query: 67 PSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 246
PS+ +NN MP +GLGT+ Q + D L+ GYR FDTA+VY E
Sbjct: 6 PSVLLNNDIQMPLLGLGTFRLQGQEDTYSAVDAALK--------AGYRAFDTAAVYRNEA 57
Query: 247 EIG 255
+G
Sbjct: 58 HLG 60
>UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 282
Score = 56.4 bits (130), Expect = 6e-07
Identities = 41/153 (26%), Positives = 69/153 (45%), Gaps = 3/153 (1%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH--WPIG 431
+V + + + RE IF+TTKL + SLK LGLDY+DLYL+H WP G
Sbjct: 58 SVGQAIRDSGIPREQIFVTTKLPAETKSYQGALNDFDRSLKNLGLDYVDLYLVHAPWPWG 117
Query: 432 -LNADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RV 608
+ Y +++D W+ +E + G KA + +A M+ + +
Sbjct: 118 QVGRVYDEANLD---VWQAMEAIYQSGRAKAIGVSNFAVRDLKNILNQATIPPMVNQIQY 174
Query: 609 TSKTFQKEMVEFCQSESVVVMGYSPFRFPGXPD 707
+ ++ +F + +++V YSP G D
Sbjct: 175 YLGFTEPKITKFSEEHAMLVEAYSPLATGGVLD 207
>UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Streptococcus agalactiae|Rep:
Oxidoreductase, aldo/keto reductase family -
Streptococcus agalactiae H36B
Length = 245
Score = 56.4 bits (130), Expect = 6e-07
Identities = 25/59 (42%), Positives = 39/59 (66%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431
EAV +++ + R++IF+ TKLW + AI+ +LK+L LDYI+LYL+H P+G
Sbjct: 56 EAVGRAIKKSGIPRKEIFVVTKLWIQDASEEKAGPAIDRALKRLQLDYINLYLIHQPMG 114
Score = 34.7 bits (76), Expect = 2.3
Identities = 21/60 (35%), Positives = 32/60 (53%)
Frame = +1
Query: 79 MNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
+NNG +P++G G + D +S V+ A+ VGYR DTAS Y E+ +G+
Sbjct: 9 LNNGVKIPSLGFGVFQIDDPLECEQS--------VLDALQVGYRLIDTASGYLNEEAVGR 60
>UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10;
Alphaproteobacteria|Rep: Aldo/keto reductase -
Mesorhizobium sp. (strain BNC1)
Length = 274
Score = 56.4 bits (130), Expect = 6e-07
Identities = 22/56 (39%), Positives = 38/56 (67%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425
A+ +E +RED+F+TTK+W + + A ++++SL+KL +D +DL L+HWP
Sbjct: 52 ALGRALERAGARREDLFLTTKVWVDNYSADKFAASVDESLEKLKVDQVDLLLLHWP 107
Score = 42.7 bits (96), Expect = 0.009
Identities = 17/45 (37%), Positives = 29/45 (64%)
Frame = +1
Query: 124 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
LGF GV + D ++ ++ A++ G+RHFDTA +Y+ E +G+
Sbjct: 14 LGF---GVFRMSDAEVERIIPAALEAGFRHFDTAQIYQNEAALGR 55
>UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 301
Score = 56.4 bits (130), Expect = 6e-07
Identities = 24/43 (55%), Positives = 31/43 (72%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 416
V R+ IFIT+KLWNT H V +A+N +LK L DY+DLYL+
Sbjct: 66 VPRDQIFITSKLWNTHHHPDHVEEAVNKTLKDLQTDYLDLYLV 108
Score = 48.8 bits (111), Expect = 1e-04
Identities = 25/62 (40%), Positives = 37/62 (59%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249
S K+++G MPA+GLGT+L SK ++ + V A+ +GYRH D A+ Y E E
Sbjct: 6 SFKLSSGYDMPAVGLGTWL---------SKPHEVENAVETALRLGYRHIDAAACYLNENE 56
Query: 250 IG 255
+G
Sbjct: 57 VG 58
Score = 35.5 bits (78), Expect = 1.3
Identities = 16/35 (45%), Positives = 22/35 (62%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
G V+ IG+SNF +++E +LK I P QIE H
Sbjct: 172 GKVRSIGVSNFTIEKIEELLKTARIPPAVNQIEAH 206
>UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG6084-PA, isoform A - Tribolium castaneum
Length = 493
Score = 56.0 bits (129), Expect = 9e-07
Identities = 38/125 (30%), Positives = 55/125 (44%), Gaps = 12/125 (9%)
Frame = +3
Query: 366 NDSLKKLGLDYIDLYLMHWPIGLNADYS-H-----------SDVDFMETWRGLEDAQRMG 509
++SLK L LDY+D+YLMHWP L S H SDVDF++TW+ +E
Sbjct: 270 SESLKNLQLDYLDVYLMHWPHALKEGPSLHPIDPKTGLFIPSDVDFVDTWKAMEKMHEKD 329
Query: 510 *LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTSKTFQKEMVEFCQSESVVVMGYSPFR 689
K+ S+ K A ++ + Q ++ +FC + V YSP
Sbjct: 330 LTKSIGISNFNSNQIDRLLKSAKIAPVINQIECHPYLNQSKLRKFCSDRGITVTSYSPLG 389
Query: 690 FPGXP 704
P P
Sbjct: 390 SPARP 394
Score = 46.4 bits (105), Expect = 7e-04
Identities = 34/142 (23%), Positives = 63/142 (44%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437
A++ +E G ++R+D+F+ +K T V A+ D+LKKL + Y+DLYL+ P
Sbjct: 61 ALQQLIEGGKIRRKDLFLMSKFCCTNTTNL-VKAALLDTLKKLQVAYLDLYLIERPPAC- 118
Query: 438 ADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTSK 617
D + +ETW +E +A S + + + +
Sbjct: 119 -----KDHNLIETWEAMEGLYSEKLTRAIGLSNFNSKQIERILENCTIRPQVNQIQCHPY 173
Query: 618 TFQKEMVEFCQSESVVVMGYSP 683
Q ++ ++C + + V+ YSP
Sbjct: 174 LNQAKLRKYCSNNGIAVISYSP 195
Score = 41.9 bits (94), Expect = 0.015
Identities = 17/34 (50%), Positives = 25/34 (73%)
Frame = +2
Query: 509 IVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
+ + IGLSNFN +Q+ER+L+ TI+P QI+ H
Sbjct: 138 LTRAIGLSNFNSKQIERILENCTIRPQVNQIQCH 171
>UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep:
Lin2739 protein - Listeria innocua
Length = 283
Score = 56.0 bits (129), Expect = 9e-07
Identities = 44/146 (30%), Positives = 67/146 (45%), Gaps = 2/146 (1%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
EAV + V R+++FITTK+W V + + SLK+LGLDYIDL L+H P
Sbjct: 53 EAVGRGIAASGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYIDLLLIHQPYN- 111
Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTS 614
D W +E+ Q G +KA S R A +++ ++
Sbjct: 112 ---------DVYGAWMAMEELQAQGKIKAIG--VSNFGVDRVVDLAAFNDITPQVNQIEI 160
Query: 615 KTFQKEM--VEFCQSESVVVMGYSPF 686
FQ++ +E + E V V ++PF
Sbjct: 161 NPFQQQSKNIEALRKEGVAVEAWAPF 186
Score = 44.0 bits (99), Expect = 0.004
Identities = 23/63 (36%), Positives = 32/63 (50%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249
++K+NNG +P +G GTY D + V AI GYRH DTA Y E+
Sbjct: 3 TVKLNNGIEVPILGFGTYQITDAG--------EAEQAVKEAIAAGYRHIDTAQSYMNEEA 54
Query: 250 IGK 258
+G+
Sbjct: 55 VGR 57
>UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep:
Aldo-keto reductase - Helicobacter hepaticus
Length = 292
Score = 56.0 bits (129), Expect = 9e-07
Identities = 42/145 (28%), Positives = 77/145 (53%), Gaps = 8/145 (5%)
Frame = +3
Query: 273 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA---- 440
V + +KRE++FIT+K+ + +I+ SLK + LD+IDL L+H P N+
Sbjct: 69 VRKSKIKREELFITSKIRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSPQPWNSFRKG 128
Query: 441 DYSHSDVDFMETWRGLEDAQRMG*LKA---SDCL-TSTSSSWRGC*KKALSNLMLFK*RV 608
DY +V E + LEDAQ+ G +++ S+ L + + C K +N +L +
Sbjct: 129 DYFKENV---EVYNALEDAQKAGKVRSIGVSNFLQKDLENILKNCKTKPAANQILC--HI 183
Query: 609 TSKTFQKEMVEFCQSESVVVMGYSP 683
+ F ++++C+ ++++ YSP
Sbjct: 184 GNTPF--TLLDYCKKQNILAEAYSP 206
Score = 42.7 bits (96), Expect = 0.009
Identities = 25/60 (41%), Positives = 34/60 (56%)
Frame = +1
Query: 79 MNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
+NNG +P +GLGT+ D N VV++ V A VGYRH DTA Y E+ +G+
Sbjct: 17 LNNGNKIPKLGLGTWR-IDDN-VVEA-------AVREAFKVGYRHIDTAQAYGNERGVGE 67
>UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4;
Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 287
Score = 56.0 bits (129), Expect = 9e-07
Identities = 29/89 (32%), Positives = 48/89 (53%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
EAV + V R ++FI++K H V +A ++SL+KLGLD++D+++ HWP+
Sbjct: 64 EAVGRGIRTAGVPRSELFISSKFNKESHSIDGVQRAYDESLRKLGLDHLDMFMCHWPVPA 123
Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKA 521
Y ++ W+GL G +KA
Sbjct: 124 LGKY-------VDAWKGLVKLLEEGRVKA 145
Score = 36.7 bits (81), Expect = 0.56
Identities = 20/66 (30%), Positives = 33/66 (50%)
Frame = +1
Query: 61 EVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240
++P LK+ +G +P +GLGT+ + + V A+ GYR DTA Y
Sbjct: 12 DIPRLKLPHGHTIPRLGLGTW---------PMLEDECETAVRFALQSGYRLVDTAFQYRN 62
Query: 241 EQEIGK 258
E+ +G+
Sbjct: 63 EEAVGR 68
>UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 310
Score = 55.6 bits (128), Expect = 1e-06
Identities = 46/150 (30%), Positives = 75/150 (50%), Gaps = 9/150 (6%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTE-VAQAINDSLKKLGLDYIDLYLMHWPIGL 434
A+K + + +KREDIFIT+KL + + + + +++ DSLK L Y+DLYL+HWP G
Sbjct: 80 ALKELLPKYNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALDTSYLDLYLIHWP-GA 138
Query: 435 NADYSHSDVD---FMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*R 605
+ +S + + TW L + Q+ G L++ S+ G + L + K
Sbjct: 139 SRILENSPDNPKLRVTTWATLVELQQKGLLRS----IGVSNYTVGHLEHLLEHCSGVKPD 194
Query: 606 VTSKTF-----QKEMVEFCQSESVVVMGYS 680
V Q E++EFC + + V YS
Sbjct: 195 VNQVECHPHFRQDELIEFCTKQGIHVQAYS 224
Score = 46.4 bits (105), Expect = 7e-04
Identities = 25/69 (36%), Positives = 40/69 (57%)
Frame = +1
Query: 49 ASTMEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTAS 228
A T + L++NNG MP +G+GTY V+ ++ ++ V+ + VG+R DTA
Sbjct: 18 ALTPTIRDLRLNNGYDMPLVGIGTY-------KVRGRE-VIKRVIDESFAVGFRSIDTAV 69
Query: 229 VYETEQEIG 255
VY E++IG
Sbjct: 70 VYRNEEDIG 78
>UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto
reductase family - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 279
Score = 55.6 bits (128), Expect = 1e-06
Identities = 22/46 (47%), Positives = 34/46 (73%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425
VKR++IF+TTK+W Q ++ ++ SL+KLG+D +DL L+HWP
Sbjct: 66 VKRDEIFLTTKVWIDQFADGDLQRSAEKSLEKLGVDQVDLLLLHWP 111
Score = 39.5 bits (88), Expect = 0.079
Identities = 20/53 (37%), Positives = 32/53 (60%)
Frame = +1
Query: 97 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
MPA+G GT+ +NG +V +A+++GYRH DTA +Y E+++G
Sbjct: 15 MPALGFGTWQL--ENGTAVP-------LVEKALEIGYRHIDTAQIYGNERDVG 58
>UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid
reductase; n=1; Gluconobacter oxydans|Rep: Putative
2,5-diketo-D-gluconic acid reductase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 279
Score = 55.6 bits (128), Expect = 1e-06
Identities = 27/83 (32%), Positives = 45/83 (54%)
Frame = +3
Query: 273 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH 452
V +G+ +IF+TTKLWN + +A +S + L +DLYL+HWP+ Y
Sbjct: 64 VGKGLEDHPEIFLTTKLWNDEQGYDSTLRAYEESARLLRRPVLDLYLIHWPMPAQGQY-- 121
Query: 453 SDVDFMETWRGLEDAQRMG*LKA 521
+ETW+ L + ++ G +K+
Sbjct: 122 -----VETWKALVELKKSGRVKS 139
Score = 39.5 bits (88), Expect = 0.079
Identities = 20/62 (32%), Positives = 34/62 (54%)
Frame = +1
Query: 73 LKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252
+ ++G MP IGLG + ++ + +VV A+ +GYR DTA +Y+ E+ +
Sbjct: 14 ISFHDGHTMPQIGLGVW---------ETPPDETAEVVKEAVKLGYRSVDTARLYKNEEGV 64
Query: 253 GK 258
GK
Sbjct: 65 GK 66
Score = 34.3 bits (75), Expect = 3.0
Identities = 16/36 (44%), Positives = 22/36 (61%)
Frame = +2
Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
+G VK IG+SNF + LER++ + P QIE H
Sbjct: 134 SGRVKSIGVSNFESEHLERIMDATGVVPVVNQIELH 169
>UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinomycetales|Rep: 2,5-didehydrogluconate reductase -
Kineococcus radiotolerans SRS30216
Length = 289
Score = 55.6 bits (128), Expect = 1e-06
Identities = 33/87 (37%), Positives = 52/87 (59%)
Frame = +3
Query: 261 VKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA 440
V + + V R++I++T+KL N H +A++DS++KL IDLYL+HWP L
Sbjct: 65 VAQGIADSGVPRDEIWVTSKLNNGFHEPDAARKAVDDSVEKLR-GPIDLYLIHWP--LPT 121
Query: 441 DYSHSDVDFMETWRGLEDAQRMG*LKA 521
Y DF+ TW+ LE+A+ G L++
Sbjct: 122 LYGG---DFVSTWKVLEEARAAGKLRS 145
Score = 46.8 bits (106), Expect = 5e-04
Identities = 23/69 (33%), Positives = 37/69 (53%)
Frame = +1
Query: 52 STMEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASV 231
S M VP++ +N+GR +P +G G + + + V A+D+GYRH DTA +
Sbjct: 8 SAMTVPTILLNDGREIPQLGFGVF---------QIEPGDTAQAVKTALDLGYRHIDTAQM 58
Query: 232 YETEQEIGK 258
Y E E+ +
Sbjct: 59 YGNEAEVAQ 67
Score = 35.1 bits (77), Expect = 1.7
Identities = 16/37 (43%), Positives = 23/37 (62%)
Frame = +2
Query: 500 ANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
A G ++ IG+SNF L+R+ +E T+ P QIE H
Sbjct: 139 AAGKLRSIGVSNFQVNHLQRLAQEATVVPAVNQIEVH 175
>UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_03001732;
n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
protein Faci_03001732 - Ferroplasma acidarmanus fer1
Length = 278
Score = 55.2 bits (127), Expect = 1e-06
Identities = 37/134 (27%), Positives = 64/134 (47%), Gaps = 3/134 (2%)
Frame = +3
Query: 291 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFM 470
KR+++F+ +K++ T + +A+N SLK L DYIDLY +H+P + VD
Sbjct: 76 KRDELFLASKVFPTHLSPKSLEKALNRSLKNLDTDYIDLYQIHFP--------NPTVDIK 127
Query: 471 ETWRGLE---DAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTSKTFQKEMVE 641
+T R +E D ++ + S+ + +G K + V + QK M++
Sbjct: 128 KTLRTMEKMVDKGKIRHIGVSNFTLNLLKRAQGILSKYEITSIQINYNVFHRNSQKGMID 187
Query: 642 FCQSESVVVMGYSP 683
+C + VM Y P
Sbjct: 188 YCNKNHIAVMAYFP 201
>UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep:
Lin2349 protein - Listeria innocua
Length = 294
Score = 55.2 bits (127), Expect = 1e-06
Identities = 23/56 (41%), Positives = 35/56 (62%)
Frame = +3
Query: 261 VKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428
V + + V RE++FI++K+WN E A +L+ L LDY+DLYL+HWP+
Sbjct: 60 VGQAILDSAVPREELFISSKVWNGDLGYDETLFAFERTLRNLKLDYLDLYLIHWPV 115
Score = 36.7 bits (81), Expect = 0.56
Identities = 21/54 (38%), Positives = 31/54 (57%)
Frame = +1
Query: 97 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
+P IGLG + +Q + + +K AI+VGYR FDTA+VY E +G+
Sbjct: 17 IPYIGLGVFQVTEQEFIAGAVEK--------AIEVGYRLFDTAAVYNNEAIVGQ 62
>UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=91; Proteobacteria|Rep: 2,5-diketo-D-gluconic acid
reductase B - Yersinia pestis
Length = 267
Score = 55.2 bits (127), Expect = 1e-06
Identities = 20/55 (36%), Positives = 37/55 (67%)
Frame = +3
Query: 261 VKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425
V ++E + R+++FITTK+W + ++ ++ +S++KL DY+DL L+HWP
Sbjct: 45 VGQAIQESGINRDELFITTKIWIANLSKDKLIPSLRESIQKLKTDYVDLTLIHWP 99
Score = 36.7 bits (81), Expect = 0.56
Identities = 15/39 (38%), Positives = 25/39 (64%)
Frame = +1
Query: 142 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
G + +D+ + D V +A+ +GYR DTA +YE E +G+
Sbjct: 9 GTFRLQDQIVIDSVSQALTLGYRAIDTAQIYENEAPVGQ 47
>UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 302
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/67 (40%), Positives = 44/67 (65%)
Frame = +1
Query: 58 MEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237
M VP +K++NG +PAIG G+ + + K ++++L D V+ AI+ G+ H DTA Y
Sbjct: 1 MTVPKVKLSNGLEIPAIGFGSGTKWKRPPGEK-EERELIDAVVSAINAGHLHIDTAEFYG 59
Query: 238 TEQEIGK 258
TE++IG+
Sbjct: 60 TEKQIGE 66
Score = 47.2 bits (107), Expect = 4e-04
Identities = 42/142 (29%), Positives = 66/142 (46%), Gaps = 5/142 (3%)
Frame = +3
Query: 273 VEEGVVKREDIFITTK-LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYS 449
++E V R+DIF+T+K L+ + ++I++ LK L DY DL+L+H P + +Y
Sbjct: 68 IKESGVPRKDIFLTSKTLFGLL--ADDPIESISNQLKTLQTDYFDLFLIHVPPNDDINY- 124
Query: 450 HSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*K----KALSNLMLFK*RVTSK 617
D + W LE G KA + + K K N + F +
Sbjct: 125 ----DLAKAWGVLEQLYEKGLAKAIGVSNHSPAELETIIKVAKIKPHVNQIEFHPLLQEP 180
Query: 618 TFQKEMVEFCQSESVVVMGYSP 683
T +V+FC+ +VV GYSP
Sbjct: 181 T--PGIVDFCKQHDIVVEGYSP 200
Score = 36.3 bits (80), Expect = 0.74
Identities = 16/35 (45%), Positives = 22/35 (62%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
G+ K IG+SN + +LE ++K IKP QIE H
Sbjct: 140 GLAKAIGVSNHSPAELETIIKVAKIKPHVNQIEFH 174
>UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 272
Score = 54.4 bits (125), Expect = 3e-06
Identities = 26/74 (35%), Positives = 43/74 (58%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDF 467
V+R+D+F+TTK+W ++ +++ +SL +L L +DL L+HWP +S V
Sbjct: 62 VRRDDVFLTTKVWTNHFAPNDLERSVKESLARLRLPSVDLLLLHWP--------NSHVPL 113
Query: 468 METWRGLEDAQRMG 509
ET L A++MG
Sbjct: 114 AETLGALSHARQMG 127
Score = 45.6 bits (103), Expect = 0.001
Identities = 24/57 (42%), Positives = 34/57 (59%)
Frame = +1
Query: 85 NGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
NG +PAIGLGT+ + + VV +A+ +GYRH DTA VY+ E+E+G
Sbjct: 7 NGARIPAIGLGTW---------ELSGRPCARVVEQALRLGYRHIDTAQVYDNEREVG 54
>UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1;
Aspergillus fumigatus|Rep: Aldehyde reductase, putative
- Aspergillus fumigatus (Sartorya fumigata)
Length = 350
Score = 54.4 bits (125), Expect = 3e-06
Identities = 23/48 (47%), Positives = 36/48 (75%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431
V RE IF+T+KLWNT H + V +A++ ++K L +Y+DLYL+ +P+G
Sbjct: 98 VPREGIFLTSKLWNTHHHPSHVEEALDKTVKDLQTNYLDLYLL-YPLG 144
>UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 323
Score = 54.0 bits (124), Expect = 3e-06
Identities = 31/87 (35%), Positives = 51/87 (58%), Gaps = 5/87 (5%)
Frame = +3
Query: 276 EEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW---PIGLNADY 446
++G KRED+FITTKL+ + + ++ + + +SL +L YIDLYL+ W P+ N D
Sbjct: 80 QQGKYKREDVFITTKLFPFKIEK-KIKEVVQNSLDQLQTSYIDLYLIQWSFTPVLTNFDG 138
Query: 447 S--HSDVDFMETWRGLEDAQRMG*LKA 521
S + E WR LE+ +G +++
Sbjct: 139 SVAVNHRPIHEVWRELEECVELGMIRS 165
Score = 49.6 bits (113), Expect = 7e-05
Identities = 24/66 (36%), Positives = 40/66 (60%)
Frame = +1
Query: 61 EVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240
++ +++NNG MP +GLGT + V + +++ ++ A+D GYR+FDTA Y
Sbjct: 11 DIKYVQLNNGYKMPLLGLGTQ---PYDIVTRVTVEEMTTLLSNALDFGYRNFDTAKQYRN 67
Query: 241 EQEIGK 258
E EIG+
Sbjct: 68 EVEIGQ 73
Score = 33.9 bits (74), Expect = 3.9
Identities = 17/49 (34%), Positives = 26/49 (53%)
Frame = +2
Query: 458 RRLHGDLARIGRCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIE 604
R +H + C G+++ IG++NFN Q + +L IKP QIE
Sbjct: 145 RPIHEVWRELEECVELGMIRSIGVANFNCQMVLDLLSYAKIKPVVNQIE 193
>UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2;
Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 281
Score = 54.0 bits (124), Expect = 3e-06
Identities = 27/68 (39%), Positives = 40/68 (58%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDF 467
+ REDIFITTKL N + +A +S K LG++++DLYL+HWP+ Y+
Sbjct: 71 IPREDIFITTKLRNGEQGNAH--EAFQNSRKALGVEFVDLYLIHWPVPSQGLYT------ 122
Query: 468 METWRGLE 491
E W+ +E
Sbjct: 123 -EAWKAME 129
Score = 42.3 bits (95), Expect = 0.011
Identities = 20/64 (31%), Positives = 34/64 (53%)
Frame = +1
Query: 64 VPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243
+P L +NNG +P +G G + + ++ + +V A++ GYRH DTA+ Y E
Sbjct: 9 IPQLTLNNGVKIPQLGFGVF---------QVPPEETQRIVEDALEAGYRHIDTAAAYRNE 59
Query: 244 QEIG 255
+G
Sbjct: 60 AGVG 63
>UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus
djamor|Rep: Reductase AKOR2 - Pleurotus djamor
Length = 306
Score = 54.0 bits (124), Expect = 3e-06
Identities = 28/58 (48%), Positives = 40/58 (68%), Gaps = 1/58 (1%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKL-WNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425
++V + E + RE++FITTKL WN H R VA++ SL+ LG +YIDLYL+H+P
Sbjct: 59 KSVGNAIRESGIPREELFITTKLPWN-HHSR--VAESFQKSLENLGTEYIDLYLVHFP 113
Score = 48.0 bits (109), Expect = 2e-04
Identities = 22/63 (34%), Positives = 36/63 (57%)
Frame = +1
Query: 67 PSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 246
P + +N G MPA+ LG + G + + + Q ++ + A+ GYRH DTA +Y TE+
Sbjct: 5 PPIVLNTGARMPALALGGWAG-----LTEEERTQAKEWFLTALKSGYRHIDTAQIYYTEK 59
Query: 247 EIG 255
+G
Sbjct: 60 SVG 62
Score = 32.7 bits (71), Expect = 9.1
Identities = 15/35 (42%), Positives = 22/35 (62%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
G VK IG+SN++ + LE +LK + P Q+E H
Sbjct: 154 GKVKAIGVSNYSIKTLEELLKTAKVVPAVNQVELH 188
>UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep:
Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 287
Score = 53.6 bits (123), Expect = 5e-06
Identities = 37/131 (28%), Positives = 57/131 (43%), Gaps = 2/131 (1%)
Frame = +3
Query: 294 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP--IGLNADYSHSDVDF 467
RED+FI +KL + H + SL++L +YIDLYL+HWP GL+ + S
Sbjct: 72 REDVFIISKLAPSDHG-LRAKEGCLRSLEQLDCEYIDLYLIHWPGMEGLDPEDSRHSEYR 130
Query: 468 METWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTSKTFQKEMVEFC 647
++W LE+ G KA T+ R + + K Q+E+ + C
Sbjct: 131 AQSWATLEEFHASGQFKAIGVSNYTAKHIRELLASCRVPPAVLQIECQPKLIQRELRDLC 190
Query: 648 QSESVVVMGYS 680
+ YS
Sbjct: 191 METGIHFQAYS 201
Score = 50.0 bits (114), Expect = 6e-05
Identities = 28/67 (41%), Positives = 39/67 (58%)
Frame = +1
Query: 58 MEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237
M VPS+++ +G MP +GLGTY D +QL+ V A+ GYR FDTA+VY
Sbjct: 1 MIVPSVRLMSGTQMPLLGLGTYKLQDH--------EQLKQSVSCALQAGYRAFDTAAVYG 52
Query: 238 TEQEIGK 258
E +G+
Sbjct: 53 NEAHLGQ 59
>UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 278
Score = 53.6 bits (123), Expect = 5e-06
Identities = 22/51 (43%), Positives = 34/51 (66%)
Frame = +3
Query: 273 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425
+ + V R+++F+TTK+ H +A SL++LGLDYIDL+L+HWP
Sbjct: 64 IRDAGVARDEVFLTTKMNKQWHSVDGARRACEASLERLGLDYIDLFLIHWP 114
Score = 38.3 bits (85), Expect = 0.18
Identities = 22/64 (34%), Positives = 32/64 (50%)
Frame = +1
Query: 67 PSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 246
P++ + NG MP +GLGT+ D + V AI+ GYR DTA Y+ E
Sbjct: 8 PTVTLANGVEMPQLGLGTW---------PMTDDEAAKAVATAIETGYRLIDTAENYKNET 58
Query: 247 EIGK 258
+G+
Sbjct: 59 GVGQ 62
>UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG05425;
n=1; Caenorhabditis briggsae|Rep: Putative
uncharacterized protein CBG05425 - Caenorhabditis
briggsae
Length = 319
Score = 45.6 bits (103), Expect(2) = 5e-06
Identities = 26/88 (29%), Positives = 48/88 (54%), Gaps = 4/88 (4%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTE--VAQAINDSLKKLGLDYIDLYLMHWPI 428
EA+K+ + + + EDIF+TTK++ ++ + + + I +SLK L +Y+DL L+H+P
Sbjct: 108 EALKILLPKYKLSTEDIFLTTKIFPVENAASGELIKKDIEESLKLLNREYLDLVLVHYPR 167
Query: 429 GLNAD--YSHSDVDFMETWRGLEDAQRM 506
D + + E W LE + +
Sbjct: 168 PFTTDDKDERNKIYRKEAWLALESLKSL 195
Score = 37.5 bits (83), Expect = 0.32
Identities = 16/30 (53%), Positives = 21/30 (70%)
Frame = +1
Query: 169 LRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
L V +A++VGYR FDTA YE E E+G+
Sbjct: 79 LLHAVDKAVEVGYRSFDTAKYYENEGELGE 108
Score = 27.5 bits (58), Expect(2) = 5e-06
Identities = 9/21 (42%), Positives = 14/21 (66%)
Frame = +3
Query: 624 QKEMVEFCQSESVVVMGYSPF 686
+KE+ EFCQ ++ +SPF
Sbjct: 213 RKELREFCQKNGILFQAFSPF 233
>UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Oceanobacillus iheyensis
Length = 280
Score = 53.2 bits (122), Expect = 6e-06
Identities = 28/83 (33%), Positives = 44/83 (53%)
Frame = +3
Query: 273 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH 452
V RE + IT+KL H + I +SL + LDY DLYL+HWP +
Sbjct: 62 VRRSSTPREQLLITSKLPGRYHHYDKAVTTIQESLYRANLDYYDLYLIHWPNPI------ 115
Query: 453 SDVDFMETWRGLEDAQRMG*LKA 521
D+ ++E W+ L +A+R G +++
Sbjct: 116 QDI-YVEAWQALIEAKRRGYIRS 137
Score = 39.9 bits (89), Expect = 0.060
Identities = 22/66 (33%), Positives = 35/66 (53%)
Frame = +1
Query: 61 EVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240
++P++ +++G +P +G GTY +GV + AID GYR DTA YE
Sbjct: 4 QIPNVTLHDGLTIPKVGFGTYRLNGNDGV---------QAINNAIDHGYRLIDTAYNYEN 54
Query: 241 EQEIGK 258
E +G+
Sbjct: 55 EGTVGE 60
>UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1;
Lactobacillus acidophilus|Rep: Reductase-dehydrogenase -
Lactobacillus acidophilus
Length = 271
Score = 53.2 bits (122), Expect = 6e-06
Identities = 35/135 (25%), Positives = 60/135 (44%), Gaps = 3/135 (2%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP---IGLNADYSHSD 458
++R DIF+TTKL +AI+ +L K GL+YIDL L+H P I +N
Sbjct: 66 IERSDIFLTTKLPTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQPWIEVNRTNDRHF 125
Query: 459 VDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTSKTFQKEMV 638
+E WR +E+A + G +++ + + V E++
Sbjct: 126 KGNLENWRAMEEAVKAGKVRSIGVSNFLQEDIENIVNNGTITPAVNQIEVHIGKVPVELM 185
Query: 639 EFCQSESVVVMGYSP 683
++C+ + + YSP
Sbjct: 186 DYCKKLGIKIEAYSP 200
Score = 44.0 bits (99), Expect = 0.004
Identities = 24/63 (38%), Positives = 36/63 (57%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249
S+ +NNG +P I LGT+L + ++ VV +A+++GYR FDTA Y E
Sbjct: 6 SVILNNGEKIPQIQLGTWL---------INNDEVNKVVRQAVNIGYRGFDTAKDYGNESG 56
Query: 250 IGK 258
+GK
Sbjct: 57 VGK 59
>UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinobacteria (class)|Rep: 2,5-didehydrogluconate
reductase - Arthrobacter sp. (strain FB24)
Length = 276
Score = 53.2 bits (122), Expect = 6e-06
Identities = 28/72 (38%), Positives = 40/72 (55%)
Frame = +3
Query: 294 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFME 473
R ++FITTKL + ++ SLK+LGLDY+DL L+HWP+ D +F+
Sbjct: 68 RSELFITTKLDGEFQGQDRAVAGLDGSLKRLGLDYVDLLLIHWPL------PRRD-EFIS 120
Query: 474 TWRGLEDAQRMG 509
TW+ E Q G
Sbjct: 121 TWKTFERLQADG 132
Score = 44.0 bits (99), Expect = 0.004
Identities = 23/63 (36%), Positives = 35/63 (55%)
Frame = +1
Query: 67 PSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 246
P +++N+G +P IGLGT+ D Q+ V+ A++ GYRH DTA Y E+
Sbjct: 5 PVIELNDGHRIPQIGLGTW---------PLDDHQVAAAVVNAVEGGYRHIDTAVKYGNEK 55
Query: 247 EIG 255
+G
Sbjct: 56 GVG 58
>UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep:
Lmo2592 protein - Listeria monocytogenes
Length = 283
Score = 52.8 bits (121), Expect = 8e-06
Identities = 31/89 (34%), Positives = 45/89 (50%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
EAV + V R+++FITTK+W V + + SLK+LGLDY+DL L+H P
Sbjct: 53 EAVGRGIAASGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYVDLLLIHQPFN- 111
Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKA 521
D W +E+ Q G ++A
Sbjct: 112 ---------DVYGAWIAMEELQASGKIRA 131
Score = 42.7 bits (96), Expect = 0.009
Identities = 23/63 (36%), Positives = 32/63 (50%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249
++K+NNG +P +G GTY D + V AI GYRH DTA Y E+
Sbjct: 3 TVKLNNGVEVPILGFGTYQITDA--------AEAEHAVKDAIKAGYRHIDTAQSYMNEEA 54
Query: 250 IGK 258
+G+
Sbjct: 55 VGR 57
>UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 289
Score = 52.8 bits (121), Expect = 8e-06
Identities = 29/85 (34%), Positives = 47/85 (55%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
E V + ++E V RE +FIT K+ ++ AI+ SL+K+ +Y DLYL+H P
Sbjct: 52 EEVAIAIKESGVPREKLFITNKV---AQGIDDIEAAIDQSLQKMQTNYFDLYLIHIPF-- 106
Query: 435 NADYSHSDVDFMETWRGLEDAQRMG 509
++ S+ DF W+ +E Q+ G
Sbjct: 107 ---FAKSEEDFQRAWKTMEGIQKAG 128
>UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2;
Halobacteriaceae|Rep: Alcohol dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 667
Score = 52.8 bits (121), Expect = 8e-06
Identities = 22/51 (43%), Positives = 28/51 (54%)
Frame = +3
Query: 282 GVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
G R +FI K+W T HRR + A SL +LG+D D Y +HWP L
Sbjct: 431 GAPDRRRVFILGKVWRTNHRRKHMLTACRSSLDELGIDAFDCYALHWPEAL 481
Score = 36.7 bits (81), Expect = 0.56
Identities = 14/35 (40%), Positives = 24/35 (68%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
G + +GL N ++ QLE V++ GT++P +Q+E H
Sbjct: 532 GWTRTLGLCNVSQTQLETVIETGTVRPALVQVERH 566
>UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 286
Score = 52.0 bits (119), Expect = 1e-05
Identities = 26/62 (41%), Positives = 38/62 (61%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249
S ++ NG +PAIGLGT+ G D N ++++++V AI GYRH D A+ Y E+
Sbjct: 7 SFRLVNGSTLPAIGLGTFQGDDGN-------EKVKNIVKAAIQAGYRHIDGAAAYGNEEA 59
Query: 250 IG 255
IG
Sbjct: 60 IG 61
Score = 37.9 bits (84), Expect = 0.24
Identities = 34/143 (23%), Positives = 63/143 (44%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
EA+ ++E + R+++ + W H +V +A++ SL+ LGL+Y+ + P
Sbjct: 58 EAIGDAIKESGISRDEL---AQPW---HEPKDVERALDLSLEALGLEYVPHAYLPGP--N 109
Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTS 614
N DY S + ETW+ +E G KA + + A + +
Sbjct: 110 NVDYERSR-KYTETWQAMEKLVDSGKAKAIGLSNFNILKTKRILEIARIRPAVNQVEAHP 168
Query: 615 KTFQKEMVEFCQSESVVVMGYSP 683
Q E++ FC+ E + +M + P
Sbjct: 169 YFPQHELLAFCEKEHIHLMAHQP 191
Score = 35.9 bits (79), Expect = 0.98
Identities = 16/36 (44%), Positives = 23/36 (63%)
Frame = +2
Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
+G K IGLSNFN + +R+L+ I+P Q+E H
Sbjct: 132 SGKAKAIGLSNFNILKTKRILEIARIRPAVNQVEAH 167
>UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus
solfataricus|Rep: Oxidoreductase - Sulfolobus
solfataricus
Length = 304
Score = 52.0 bits (119), Expect = 1e-05
Identities = 24/45 (53%), Positives = 30/45 (66%)
Frame = +3
Query: 291 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425
KRED+FI TK+ R +V +A SLK+L YIDLYL+HWP
Sbjct: 72 KREDLFIITKVSIDHLRYDDVLKASEGSLKRLNTSYIDLYLVHWP 116
>UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG07276.1 - Gibberella zeae PH-1
Length = 284
Score = 51.6 bits (118), Expect = 2e-05
Identities = 43/150 (28%), Positives = 78/150 (52%), Gaps = 9/150 (6%)
Frame = +3
Query: 261 VKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKL----GLD-YIDLYLMHWP 425
V+ +E+ V RED+F+TTK+ + R+TE +A D ++ + G D Y+DL LMH P
Sbjct: 62 VREAIEQSGVFREDLFLTTKV-GSPRRKTEKTEAYEDVIEAVERIAGKDGYVDLLLMHVP 120
Query: 426 IGLNADYSHSDVDFMETWRGLEDAQRMG----*LKASDCLTSTSSSWRGC*KKALSNLML 593
G + ++ HS + ME + A+ +G ++ D + ++ W +++ + L
Sbjct: 121 -GPSREHRHSLWEAMERAKREARARNIGVSNFRVRHLDEMKEYATEW----PPSVNQIEL 175
Query: 594 FK*RVTSKTFQKEMVEFCQSESVVVMGYSP 683
QKE+V++CQ +++ YSP
Sbjct: 176 H-----PWCQQKEVVKYCQDNEIIIEAYSP 200
>UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=5; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus brevis (strain ATCC 367 / JCM 1170)
Length = 282
Score = 51.6 bits (118), Expect = 2e-05
Identities = 35/130 (26%), Positives = 60/130 (46%)
Frame = +3
Query: 294 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFME 473
RE +F+T+K+ + +A+ SLK+L DY+DL L+HWP+ H F +
Sbjct: 72 REGLFLTSKVAEIVQGYDQTMKAVEGSLKRLQTDYLDLLLIHWPV-----REH----FFD 122
Query: 474 TWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTSKTFQKEMVEFCQS 653
TWR LE + G +K+ T + KA ++ + Q+ + ++ Q
Sbjct: 123 TWRALEQLKADGQVKSIGVSNYTIAHLELLATKAKEMPVVNQVEYHPYLNQQALADYDQE 182
Query: 654 ESVVVMGYSP 683
+V +SP
Sbjct: 183 HDIVTEAWSP 192
Score = 43.6 bits (98), Expect = 0.005
Identities = 24/60 (40%), Positives = 31/60 (51%)
Frame = +1
Query: 76 KMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
K+ +GR MP +G GTYL DQ + + A D GYR FDTA +Y E +G
Sbjct: 11 KLADGRQMPVMGFGTYLLNDQ--------PTMNTAIQTAWDAGYRMFDTAMLYRNEDILG 62
>UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 301
Score = 51.6 bits (118), Expect = 2e-05
Identities = 22/47 (46%), Positives = 32/47 (68%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428
+ R ++FITTK+ + R V Q+++ SL LG DYIDL L+HWP+
Sbjct: 90 IDRRELFITTKVNTMEMRGGTVRQSLDKSLADLGTDYIDLVLIHWPV 136
Score = 46.8 bits (106), Expect = 5e-04
Identities = 26/66 (39%), Positives = 38/66 (57%)
Frame = +1
Query: 61 EVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240
+VP++K+NNG MP +G+GT+L D + V AI VG+R DTA Y
Sbjct: 28 KVPTVKLNNGMEMPQLGVGTFLVKD----------NAAERVCHAIKVGFRLIDTAQGYGN 77
Query: 241 EQEIGK 258
E+E+G+
Sbjct: 78 EKEVGE 83
>UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6;
n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 -
Apis mellifera
Length = 292
Score = 51.2 bits (117), Expect = 2e-05
Identities = 36/145 (24%), Positives = 70/145 (48%), Gaps = 4/145 (2%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTE-VAQAINDSLKKLGLDYIDLYLMHWPIGL 434
A+K + + ++R DIFITTKL + + + + Q + SLK YIDLYL+HWP
Sbjct: 62 ALKNLLPKYNLQRSDIFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYLIHWPGAT 121
Query: 435 NADYSHSDVDFM--ETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNL-MLFK*R 605
+ ++ + +TW L D ++ G +++ T + + L + +
Sbjct: 122 RIPETSTNNPSLRAKTWNKLVDLKKQGFIRSIGVSNFTIKHLQELLQNCKDILPAVNQVE 181
Query: 606 VTSKTFQKEMVEFCQSESVVVMGYS 680
+ Q+E++++C + + + YS
Sbjct: 182 LHPHYRQEELIKYCNEKGIHIQAYS 206
Score = 36.3 bits (80), Expect = 0.74
Identities = 23/65 (35%), Positives = 37/65 (56%), Gaps = 1/65 (1%)
Frame = +1
Query: 64 VPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQL-RDVVMRAIDVGYRHFDTASVYET 240
V ++ +++G MP IG GTY K + ++L VV +++VG+R DTA Y
Sbjct: 5 VRNVCLSSGYDMPLIGFGTY---------KIQGRELVYQVVDESLNVGFRSIDTAVGYRN 55
Query: 241 EQEIG 255
E++IG
Sbjct: 56 EEDIG 60
>UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 295
Score = 51.2 bits (117), Expect = 2e-05
Identities = 27/86 (31%), Positives = 48/86 (55%), Gaps = 1/86 (1%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
+A++ +EG KRED+F+ TKL++ ++ T+V + SL+ L +YIDLYL+H+
Sbjct: 61 DALQEIYKEGKYKREDLFLVTKLFS--NKNTKVEDQVRQSLQNLQTNYIDLYLLHYASSP 118
Query: 435 NAD-YSHSDVDFMETWRGLEDAQRMG 509
D + + + W E+ + G
Sbjct: 119 PTDQFELTHKPVFQVWAEFEELVQKG 144
Score = 46.8 bits (106), Expect = 5e-04
Identities = 25/57 (43%), Positives = 35/57 (61%)
Frame = +1
Query: 85 NGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
NG +P GLGTY V SK++ + + A+D+GYRH DTA +YE E++IG
Sbjct: 12 NGSKLPVFGLGTYK-------VVSKEEMVT-FLRTALDLGYRHIDTAIMYENEKQIG 60
>UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase
family protein; n=3; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 299
Score = 51.2 bits (117), Expect = 2e-05
Identities = 28/69 (40%), Positives = 45/69 (65%), Gaps = 1/69 (1%)
Frame = +1
Query: 52 STMEVPS-LKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTAS 228
S+ E+ + ++NG+ MPA GLG+ V+S + ++ +++ +A+DVGYRH DTA
Sbjct: 2 SSQEIQKVITLSNGQKMPAFGLGS-------SRVQSVE-EVTNLIRKALDVGYRHIDTAQ 53
Query: 229 VYETEQEIG 255
+YE EQ IG
Sbjct: 54 MYENEQFIG 62
Score = 46.8 bits (106), Expect = 5e-04
Identities = 28/88 (31%), Positives = 45/88 (51%), Gaps = 4/88 (4%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437
A+K EG KREDIF+ TK + + + + L+KL +DY+DL L+H P+
Sbjct: 64 ALKTIFGEGKYKREDIFLVTK--QASIKGVSCLEIMKEQLQKLQVDYVDLLLIHVPLAAP 121
Query: 438 AD----YSHSDVDFMETWRGLEDAQRMG 509
+D ++H V + W E+ +G
Sbjct: 122 SDDYQQWNHKPVH--QIWAEFEEIHSLG 147
Score = 35.5 bits (78), Expect = 1.3
Identities = 18/38 (47%), Positives = 24/38 (63%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGHLQN 619
G+ KG+G+SNFN Q + +L IKP QIE H+ N
Sbjct: 147 GLAKGLGVSNFNCQMIIDLLAYCKIKPLVNQIELHVFN 184
>UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:
ENSANGP00000029046 - Anopheles gambiae str. PEST
Length = 331
Score = 50.8 bits (116), Expect = 3e-05
Identities = 26/57 (45%), Positives = 36/57 (63%), Gaps = 1/57 (1%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHR-RTEVAQAINDSLKKLGLDYIDLYLMHWP 425
A+K + + +KREDIFIT+KL + + V Q + SL L DY+DLYL+HWP
Sbjct: 88 ALKTLLPKYNLKREDIFITSKLISQSGKDEAFVEQMVRKSLANLQTDYLDLYLIHWP 144
Score = 40.3 bits (90), Expect = 0.045
Identities = 23/62 (37%), Positives = 31/62 (50%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249
+ K+N G +P G GTY Q + + D A++ GYRH DTA VY E+
Sbjct: 33 TFKLNTGFDIPLAGFGTYQIHGQELIYQVLDY--------ALEAGYRHIDTAVVYRNEEY 84
Query: 250 IG 255
IG
Sbjct: 85 IG 86
>UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=3; Archaea|Rep: 2,5-diketo-D-gluconic acid reductase A
- Sulfolobus acidocaldarius
Length = 267
Score = 50.8 bits (116), Expect = 3e-05
Identities = 21/44 (47%), Positives = 29/44 (65%)
Frame = +3
Query: 294 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425
RE +FITTK+W + + ++ SLK+L YIDLYL+HWP
Sbjct: 72 RESLFITTKVWPNHLKYDDTIKSALASLKRLNTKYIDLYLIHWP 115
>UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2;
Halobacteriaceae|Rep: Aldo/keto reductase - Halorubrum
lacusprofundi ATCC 49239
Length = 665
Score = 50.8 bits (116), Expect = 3e-05
Identities = 21/51 (41%), Positives = 28/51 (54%)
Frame = +3
Query: 282 GVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434
G RE +F+ K W T HRR + A S ++LG+D D Y +HWP L
Sbjct: 429 GAPDRERVFLLGKAWRTNHRREHLLAACAGSREELGIDAFDCYALHWPSAL 479
Score = 33.9 bits (74), Expect = 3.9
Identities = 14/35 (40%), Positives = 22/35 (62%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
G + +G+ N ++ QLE VL+ G I P +Q+E H
Sbjct: 530 GWARTLGICNVSRAQLETVLETGEIDPALVQVERH 564
>UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 273
Score = 50.4 bits (115), Expect = 4e-05
Identities = 31/132 (23%), Positives = 61/132 (46%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDF 467
+ R ++F+TTK+W + ++ +SL +L DY+DL L+HWP + D S ++
Sbjct: 62 ISRGELFVTTKVWFDNLSADKFITSVQNSLTQLNTDYVDLLLVHWP---SPDNKVSMAEY 118
Query: 468 METWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTSKTFQKEMVEFC 647
++ + ++ + S+ S K +++ + V KE+V +C
Sbjct: 119 LKELKACKERGLTRHIGVSNFTQSQLDEALSILGK--DHILTNQIEVHPNFQNKELVAYC 176
Query: 648 QSESVVVMGYSP 683
Q ++ V Y P
Sbjct: 177 QRNNIQVTAYMP 188
Score = 42.3 bits (95), Expect = 0.011
Identities = 24/53 (45%), Positives = 29/53 (54%)
Frame = +1
Query: 97 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
+P G GTY +K D +L V A+DVGYRH DTA YE E E+G
Sbjct: 11 IPTPGFGTYR-------LKGDDAKL--AVENALDVGYRHIDTAQAYENEAEVG 54
>UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1;
Erythrobacter sp. SD-21|Rep: Putative oxidoreductase
protein - Erythrobacter sp. SD-21
Length = 272
Score = 50.4 bits (115), Expect = 4e-05
Identities = 26/83 (31%), Positives = 44/83 (53%)
Frame = +3
Query: 273 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH 452
V +GV + DIF+ TK+WN +A L++LG +++D+ L+HWP
Sbjct: 57 VGKGVGEWSDIFLQTKIWNDSQGYDRTLRAAEKCLERLGREHVDMLLIHWPC------PE 110
Query: 453 SDVDFMETWRGLEDAQRMG*LKA 521
D F++TW+ L + + G K+
Sbjct: 111 KD-QFVDTWKALIELRDAGKAKS 132
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/66 (34%), Positives = 38/66 (57%)
Frame = +1
Query: 61 EVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240
+ P+L +N+GR +P +G GT+ + +++ V AIDVGY DTA++Y
Sbjct: 3 DYPTLNLNDGRQIPQLGFGTW---------QMEEEDAPQAVSTAIDVGYWLIDTAAIYGN 53
Query: 241 EQEIGK 258
E+ +GK
Sbjct: 54 EKGVGK 59
Score = 33.9 bits (74), Expect = 3.9
Identities = 15/35 (42%), Positives = 22/35 (62%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
G K IG+SNF ++ L+R++ E + P QIE H
Sbjct: 128 GKAKSIGVSNFREEDLKRIIDETGVTPALNQIELH 162
>UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 293
Score = 50.4 bits (115), Expect = 4e-05
Identities = 22/63 (34%), Positives = 36/63 (57%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249
++K+ +G +P +G G Y +++ K+ D V +AID GYRH DTA Y E+
Sbjct: 8 TIKLASGNLIPRLGFGVY---------QARSKECEDAVKKAIDTGYRHVDTAQAYHNEEN 58
Query: 250 IGK 258
+G+
Sbjct: 59 VGR 61
>UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 313
Score = 50.4 bits (115), Expect = 4e-05
Identities = 40/142 (28%), Positives = 71/142 (50%), Gaps = 5/142 (3%)
Frame = +3
Query: 273 VEEGVVKREDIFITTKLWNTQHRRT-EVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYS 449
++E R +IFIT K ++TQ + T + + +N LK LGLDY+DLYL+H P + ++
Sbjct: 74 LKESSKPRSEIFITDK-YSTQTKFTNDPIEGLNTGLKTLGLDYVDLYLIHSPF-FDPEFK 131
Query: 450 HSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*K----KALSNLMLFK*RVTSK 617
S + + W+ +E + G K+ + + K K N + F + ++
Sbjct: 132 GS-LTLEKVWKDMETLYKEGKAKSIGVSNFSVKNIEEILKIAGIKPQVNQIEFNAFLQNQ 190
Query: 618 TFQKEMVEFCQSESVVVMGYSP 683
T +V +CQ ++ + YSP
Sbjct: 191 T--PGIVNYCQKNNIQLEAYSP 210
Score = 35.1 bits (77), Expect = 1.7
Identities = 19/40 (47%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIE--GHLQN 619
G K IG+SNF+ + +E +LK IKP QIE LQN
Sbjct: 150 GKAKSIGVSNFSVKNIEEILKIAGIKPQVNQIEFNAFLQN 189
>UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 289
Score = 50.0 bits (114), Expect = 6e-05
Identities = 22/48 (45%), Positives = 34/48 (70%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431
VKRE+IF+TTK+W + + R +++ +SLK+L Y+DL L+H P G
Sbjct: 68 VKREEIFLTTKVWVSNYER--CYESVIESLKRLDTSYLDLILLHQPFG 113
Score = 43.6 bits (98), Expect = 0.005
Identities = 23/67 (34%), Positives = 34/67 (50%)
Frame = +1
Query: 55 TMEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY 234
T V + +NNG +P+IG G + + ++ D V +AI +GYR DTA Y
Sbjct: 3 TSNVKLITLNNGNKIPSIGFGVF---------QIPKEETADCVKKAISIGYRLIDTAQAY 53
Query: 235 ETEQEIG 255
E+E G
Sbjct: 54 HNEKETG 60
>UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 682
Score = 50.0 bits (114), Expect = 6e-05
Identities = 29/71 (40%), Positives = 43/71 (60%)
Frame = +3
Query: 273 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH 452
V++ V R +++TTKL N H T V +A++ SL +LG+DY+DLYLM
Sbjct: 469 VKDSGVSRSQVWVTTKLDNRWH--TRVQEALDMSLSELGMDYVDLYLM-----------L 515
Query: 453 SDVDFMETWRG 485
+D DF++TW G
Sbjct: 516 ADWDFVKTWYG 526
Score = 38.3 bits (85), Expect = 0.18
Identities = 24/63 (38%), Positives = 32/63 (50%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249
S ++N G +PA+GLGT + G+V V A+ GYRH DTA E E
Sbjct: 413 SFRLNTGALIPAVGLGTRRA-QKPGLVYR-------AVRSALKTGYRHIDTAMSSGVEHE 464
Query: 250 IGK 258
IG+
Sbjct: 465 IGQ 467
>UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1;
Picrophilus torridus|Rep: 2,5-diketo-D-gluconic acid
reductase - Picrophilus torridus
Length = 283
Score = 50.0 bits (114), Expect = 6e-05
Identities = 33/136 (24%), Positives = 63/136 (46%), Gaps = 4/136 (2%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDF 467
++ ++FI TK++ + + +A +SLK+L + IDLY +HWP + VD
Sbjct: 59 IESREVFIATKVFPNHFKYDSLIRACENSLKRLNVKTIDLYQLHWP--------NRHVDI 110
Query: 468 METWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RV----TSKTFQKEM 635
ET + +E G ++ + + A+S + +V + + E+
Sbjct: 111 KETMKAMEHLVDTGMIRYIGVSNFNVNELKSA-MSAMSKYEIVSNQVEYNPLVRYIEPEI 169
Query: 636 VEFCQSESVVVMGYSP 683
EFC+ S+ ++ YSP
Sbjct: 170 SEFCRKNSISIIAYSP 185
>UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase
oxidoreductase protein; n=1; Spiroplasma citri|Rep:
Putative aldo/keto reductase oxidoreductase protein -
Spiroplasma citri
Length = 138
Score = 49.6 bits (113), Expect = 7e-05
Identities = 20/54 (37%), Positives = 35/54 (64%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 416
E + +++ V R++IF+T+K+WN H+ Q I++ LK+L DY+DL L+
Sbjct: 57 ELIGKAIKDSGVPRKEIFLTSKIWNANHKYDAALQEIDNILKRLDTDYLDLCLV 110
Score = 48.0 bits (109), Expect = 2e-04
Identities = 26/62 (41%), Positives = 37/62 (59%)
Frame = +1
Query: 73 LKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252
LK+ NG +P IGLGTY D++ V ++ ++ A+ GYRH DTA +Y E+ I
Sbjct: 8 LKLFNGVEIPLIGLGTYKMTDEHEVYQA--------IITALQNGYRHIDTAQIYGNEELI 59
Query: 253 GK 258
GK
Sbjct: 60 GK 61
>UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:
Aldo/keto reductase - Kineococcus radiotolerans SRS30216
Length = 343
Score = 49.6 bits (113), Expect = 7e-05
Identities = 17/48 (35%), Positives = 31/48 (64%)
Frame = +3
Query: 282 GVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425
G V R+++F+ +K+WN H + +++ SL+ L LD++D +HWP
Sbjct: 79 GGVDRDELFVVSKVWNDAHAPADAVASVHRSLRDLRLDHLDAVFVHWP 126
Score = 38.7 bits (86), Expect = 0.14
Identities = 21/65 (32%), Positives = 34/65 (52%)
Frame = +1
Query: 64 VPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243
VP ++ G +PAIG+GT+ G + ++ V A+ GYR D A+VY E
Sbjct: 13 VPRRELRGGATVPAIGIGTF------GSDRYSPAEVAAAVAGAVAAGYRLVDCAAVYGNE 66
Query: 244 QEIGK 258
++G+
Sbjct: 67 AQVGE 71
>UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1;
Sulfitobacter sp. NAS-14.1|Rep: Putative uncharacterized
protein - Sulfitobacter sp. NAS-14.1
Length = 274
Score = 49.6 bits (113), Expect = 7e-05
Identities = 20/46 (43%), Positives = 30/46 (65%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425
V+R+++F+TTK+ A + SLK+LG DY+DL L+HWP
Sbjct: 62 VRRDEVFLTTKILPEHFSPEAFTAAADASLKRLGTDYVDLLLLHWP 107
Score = 37.1 bits (82), Expect = 0.42
Identities = 16/45 (35%), Positives = 27/45 (60%)
Frame = +1
Query: 124 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
LGF G + + + D+V A+ G+RH DTA Y+ E+++G+
Sbjct: 14 LGF---GTFQLEQDTVADMVAAALSEGFRHIDTAQAYQNEEQVGE 55
>UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 153
Score = 49.6 bits (113), Expect = 7e-05
Identities = 24/76 (31%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +3
Query: 267 MKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-NAD 443
+K + V +E I+ ++WN+ H V + +++ LG+ Y+DLYL+HWPI NA+
Sbjct: 3 LKFLKSVKLKEKIYFI-QVWNSCHNSNLVIKHCEKTIEDLGIGYLDLYLIHWPIAFKNAN 61
Query: 444 YSHSDVDFMETWRGLE 491
S +D+++ G +
Sbjct: 62 PSDVTIDWIKDENGYQ 77
>UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 186
Score = 49.6 bits (113), Expect = 7e-05
Identities = 31/82 (37%), Positives = 46/82 (56%), Gaps = 4/82 (4%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP-IGLNADYSHS--- 455
V RE+IFIT+KLWNT + + + + +L LG+D +DLY + +N D + +
Sbjct: 51 VPREEIFITSKLWNT--HQPNIKEGLQKTLDALGVDCLDLYNETSDLLPVNPDGTRAVDR 108
Query: 456 DVDFMETWRGLEDAQRMG*LKA 521
D ETWR +ED + G KA
Sbjct: 109 SWDQSETWRQMEDFYKSGKAKA 130
Score = 33.9 bits (74), Expect = 3.9
Identities = 18/50 (36%), Positives = 27/50 (54%)
Frame = +1
Query: 76 KMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTA 225
K+N G +PA+GLGT+ KS+ ++ + A+ GYRH D A
Sbjct: 8 KLNPGALIPAVGLGTW---------KSEPGEVARALAHALKTGYRHIDAA 48
>UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 287
Score = 49.6 bits (113), Expect = 7e-05
Identities = 37/138 (26%), Positives = 65/138 (47%), Gaps = 7/138 (5%)
Frame = +3
Query: 291 KREDIFITTKLWNTQHRRTEVAQAINDSLKKL-GLDYIDLYLMHWPIGLNADYSHSDVDF 467
KRED+ TTK+ N +++ +SL K+ L+YIDL L+H P+
Sbjct: 75 KREDVLYTTKITNLNQGYDRTWRSLKESLNKVKHLEYIDLVLIHDPLS-------DKKTR 127
Query: 468 METWRGLEDAQRMG*LKASDCLT------STSSSWRGC*KKALSNLMLFK*RVTSKTFQK 629
+ETW+ L++A G +K+ W G K + N + ++ +K
Sbjct: 128 IETWKALQEAVDSGMVKSIGVSNFGKHHIQELYDWEGLKYKPIVNQI----ELSPWLMRK 183
Query: 630 EMVEFCQSESVVVMGYSP 683
++V++CQ+ +V+ Y P
Sbjct: 184 DLVDYCQNLGIVLEAYCP 201
Score = 42.3 bits (95), Expect = 0.011
Identities = 24/58 (41%), Positives = 31/58 (53%)
Frame = +1
Query: 85 NGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258
NG +PA G+G YL Q +V +A+DVGYR DTA YE E+E G+
Sbjct: 14 NGSRIPACGVGVYL---------LPASQTAGIVEKALDVGYRLIDTAQEYENERETGE 62
>UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6;
Halobacteriaceae|Rep: Aldehyde reductase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 279
Score = 49.6 bits (113), Expect = 7e-05
Identities = 20/48 (41%), Positives = 30/48 (62%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431
V R+DIF+ TK+W + +V + +SL KLG+D +DL +HW G
Sbjct: 69 VDRDDIFLATKVWISNLSHDDVIETTEESLDKLGVDSVDLLYVHWAAG 116
Score = 39.5 bits (88), Expect = 0.079
Identities = 20/53 (37%), Positives = 28/53 (52%)
Frame = +1
Query: 97 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
MP +GLGT+ D +Q + V A++ GYRH DTA Y+ E +G
Sbjct: 17 MPMLGLGTWQNEDA--------EQCAESVRTALEAGYRHIDTAQAYDNESAVG 61
>UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula
marismortui|Rep: Oxidoreductase - Haloarcula marismortui
(Halobacterium marismortui)
Length = 264
Score = 49.6 bits (113), Expect = 7e-05
Identities = 21/44 (47%), Positives = 29/44 (65%)
Frame = +3
Query: 294 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425
RED+F+T+K+ V +A SL +LG DY+DLYL+HWP
Sbjct: 50 REDVFLTSKVLPKHLDYESVIEACEASLDRLGTDYLDLYLVHWP 93
>UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 107
Score = 49.2 bits (112), Expect = 1e-04
Identities = 25/67 (37%), Positives = 41/67 (61%), Gaps = 1/67 (1%)
Frame = +1
Query: 61 EVPSLKMNNGRXMPAIGLGTYLG-FDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237
++P + + +G MP IG+GT F Q +L +++ AI+VGYRHFDTA+ Y
Sbjct: 6 QIPGVLLRSGXEMPLIGMGTATSPFPQ-------PHRLTSILVDAIEVGYRHFDTAAHYA 58
Query: 238 TEQEIGK 258
+E+ +G+
Sbjct: 59 SEEPLGR 65
>UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=10;
Pezizomycotina|Rep: Related to aldo-keto reductase YPR1
- Neurospora crassa
Length = 322
Score = 49.2 bits (112), Expect = 1e-04
Identities = 38/144 (26%), Positives = 66/144 (45%), Gaps = 7/144 (4%)
Frame = +3
Query: 273 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH 452
+ + + R ++ITTK V Q+ N SL+KLGLDY+DLYL+H P ++
Sbjct: 91 IAQSKLPRSSLYITTK--TIVRAGDTVTQSFNRSLEKLGLDYVDLYLLHSPF-----FAK 143
Query: 453 SDVDFMETWRGLEDAQRMG*LKA---SDCLTSTSSSW----RGC*KKALSNLMLFK*RVT 611
+ WR +E + G K+ S+ L S + G + N + + +
Sbjct: 144 NPEQLQAAWREMEKIKDSGMAKSIGVSNFLISHLQTLFDIPGGLQYPPVVNQIEYHPYLQ 203
Query: 612 SKTFQKEMVEFCQSESVVVMGYSP 683
+++V FC+ + + + YSP
Sbjct: 204 HVVEGEDLVAFCREKHIAIAAYSP 227
Score = 42.7 bits (96), Expect = 0.009
Identities = 20/66 (30%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
Frame = +1
Query: 64 VPSLKMNNGRXMPAIGLGTYLGFDQNG-VVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240
+PSLK+++G +P +G G ++G + + + + + A++ GY H D A VY
Sbjct: 24 IPSLKLSDGNEIPMLGYGLGTANYKSGDSADTISEPIVNATLTALNAGYAHLDGAEVYGN 83
Query: 241 EQEIGK 258
E E+G+
Sbjct: 84 EVELGR 89
>UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4;
Thermoproteaceae|Rep: Aldo-keto reductase, putative -
Pyrobaculum aerophilum
Length = 317
Score = 49.2 bits (112), Expect = 1e-04
Identities = 30/131 (22%), Positives = 65/131 (49%), Gaps = 1/131 (0%)
Frame = +3
Query: 294 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDV-DFM 470
R+ ++I TK+ RR ++ ++ + ++LG+D IDLY +HWP A + ++ + + M
Sbjct: 76 RDHVYIATKIHGDWLRRIDILTSVENQRRRLGVDAIDLYQIHWP----ACWHNTPICETM 131
Query: 471 ETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTSKTFQKEMVEFCQ 650
+T L D + + S+ + R C + + + + KE++ + +
Sbjct: 132 KTLEELVDRGLVRYIGVSNFPLALLERARSCLSRVDIVTSQNRYNIIEREADKELLPYLR 191
Query: 651 SESVVVMGYSP 683
E +V++ +SP
Sbjct: 192 REGIVLIAWSP 202
>UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep:
Tlr1054 protein - Synechococcus elongatus
(Thermosynechococcus elongatus)
Length = 320
Score = 48.8 bits (111), Expect = 1e-04
Identities = 32/130 (24%), Positives = 55/130 (42%)
Frame = +3
Query: 294 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFME 473
R+ TK++ R +V A SL+ L DYIDLY +HWP G + V E
Sbjct: 74 RDRCVYATKVFANHLRYKDVIAACERSLRNLNTDYIDLYQIHWPAG---SFGSEIVPIEE 130
Query: 474 TWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTSKTFQKEMVEFCQS 653
T + + + Q G ++A + + + + + + + E++ FC
Sbjct: 131 TMQAMVELQAAGKIRAIGVSNFSRAQLAEAMQYGRIESVQPPYSLFWRWAEAELIPFCIE 190
Query: 654 ESVVVMGYSP 683
+ V+ YSP
Sbjct: 191 HEITVLAYSP 200
>UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1;
Actinobacillus succinogenes 130Z|Rep: Aldo/keto
reductase precursor - Actinobacillus succinogenes 130Z
Length = 315
Score = 48.8 bits (111), Expect = 1e-04
Identities = 25/57 (43%), Positives = 36/57 (63%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425
+AV V + + RE+IFITTK++ + A AIN+ L+ L DYIDL L+H+P
Sbjct: 93 QAVGRAVRDSGIPREEIFITTKIYGSGDYANAEA-AINERLRLLDTDYIDLLLLHYP 148
Score = 39.1 bits (87), Expect = 0.10
Identities = 22/63 (34%), Positives = 32/63 (50%)
Frame = +1
Query: 70 SLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249
++K+NNG MP IG+G + +Q V A+ GYR DTA +Y EQ
Sbjct: 44 TVKLNNGIEMPIIGIGVWT---------LTPEQTEKSVGEALKAGYRLIDTARMYRNEQA 94
Query: 250 IGK 258
+G+
Sbjct: 95 VGR 97
Score = 38.3 bits (85), Expect = 0.18
Identities = 15/47 (31%), Positives = 28/47 (59%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGHLQNVSERNGGIL 646
G ++ IGLSN++++ R+++ TI P +Q E H+ N ++ L
Sbjct: 166 GKIRAIGLSNYHRKTFNRIMQAATITPAVVQNEVHIYNQDKQTKAFL 212
>UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=1; Rhodobacterales bacterium HTCC2150|Rep:
2,5-diketo-D-gluconic acid reductase A - Rhodobacterales
bacterium HTCC2150
Length = 334
Score = 48.8 bits (111), Expect = 1e-04
Identities = 29/90 (32%), Positives = 46/90 (51%), Gaps = 7/90 (7%)
Frame = +3
Query: 261 VKMKVEEGVVKREDIFITTKLW-------NTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 419
+K ++ + R+D+F+T KLW + + + + SL +LGLDY+DLYL+H
Sbjct: 94 IKAGLQSAGITRKDLFVTAKLWPGNPAWGDAPKTKAQTLDECDASLARLGLDYVDLYLIH 153
Query: 420 WPIGLNADYSHSDVDFMETWRGLEDAQRMG 509
P G D+ +E WR L + Q G
Sbjct: 154 APYG-------GDMR-LEQWRALLELQANG 175
Score = 42.7 bits (96), Expect = 0.009
Identities = 23/67 (34%), Positives = 34/67 (50%)
Frame = +1
Query: 55 TMEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY 234
T + +N +PA+G GTYL + + D + + AI GYRH DTAS Y
Sbjct: 34 TNTATTFTLNTTTTIPAVGFGTYL-------ISNDDA--KSTISAAIQAGYRHIDTASGY 84
Query: 235 ETEQEIG 255
+ E+ +G
Sbjct: 85 QNEKTVG 91
Score = 38.3 bits (85), Expect = 0.18
Identities = 18/37 (48%), Positives = 22/37 (59%)
Frame = +2
Query: 500 ANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
ANG + IG+SNFN+ L + G PDA QIE H
Sbjct: 173 ANGKARSIGVSNFNESHLNEIKAAGLPMPDANQIELH 209
>UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus
terreus NIH2624|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 292
Score = 48.8 bits (111), Expect = 1e-04
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 261 VKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA 440
V + + E + RE +FITTK+ +V A++ SL++L LDY+DLYL+H P +
Sbjct: 65 VGIAIRESGIPREQLFITTKVLEGWK---DVPGALDASLERLQLDYVDLYLLHNPYVI-- 119
Query: 441 DYSHSDVDFMETWRGLEDAQRMG 509
+ D W+GLE + G
Sbjct: 120 ---PNLTDIQSAWKGLEAVKATG 139
Score = 46.4 bits (105), Expect = 7e-04
Identities = 20/66 (30%), Positives = 38/66 (57%)
Frame = +1
Query: 58 MEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237
M+ P+L + +G +P +G GT + ++ + +L +V+ A++ G+ H D A Y
Sbjct: 1 MKWPALSLKDGNLVPILGFGTGTAWYKDDPNDPTNPELIEVLKAALEKGFHHIDAADSYG 60
Query: 238 TEQEIG 255
TE+E+G
Sbjct: 61 TEREVG 66
>UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 275
Score = 48.8 bits (111), Expect = 1e-04
Identities = 32/88 (36%), Positives = 50/88 (56%)
Frame = +3
Query: 258 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437
A+ +EE KREDI+ T+KL + ++ ++ +I+ S+K GL YIDL+L+H P G
Sbjct: 59 AILKFMEETGTKREDIWFTSKLNDLSGYKSTLS-SIDASVKACGLGYIDLFLLHSPYG-- 115
Query: 438 ADYSHSDVDFMETWRGLEDAQRMG*LKA 521
D +E+W+ LE G L+A
Sbjct: 116 --------DRIESWKALEKGVEEGKLRA 135
Score = 36.7 bits (81), Expect = 0.56
Identities = 21/62 (33%), Positives = 32/62 (51%)
Frame = +1
Query: 73 LKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252
+K+NNG P G+Y+ V ++K D V A+ GYRH D+A +Y E +
Sbjct: 6 VKLNNGLKCPQFAYGSYM------VNRTK---CFDSVYAALQCGYRHIDSAQMYHNEADC 56
Query: 253 GK 258
G+
Sbjct: 57 GR 58
>UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5;
Archaea|Rep: Myo-inositol degradation - Pyrococcus
abyssi
Length = 279
Score = 48.8 bits (111), Expect = 1e-04
Identities = 25/52 (48%), Positives = 31/52 (59%)
Frame = +3
Query: 270 KVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425
K EG RE+IFI +K+W T +A S K+LG YIDLYL+HWP
Sbjct: 75 KAIEGF-NREEIFIVSKVWPTHFGYESAKKAARASAKRLG-TYIDLYLLHWP 124
>UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;
Lactobacillus|Rep: Aldo/keto reductase family enzyme -
Lactobacillus casei (strain ATCC 334)
Length = 281
Score = 48.4 bits (110), Expect = 2e-04
Identities = 34/140 (24%), Positives = 67/140 (47%), Gaps = 5/140 (3%)
Frame = +3
Query: 282 GVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDV 461
G R +I++ +K + + + ++ A+ +SLK+L DY+DLYL+HW
Sbjct: 67 GDYDRANIYLISKFYPSHADKRQMLTALKNSLKRLQTDYLDLYLLHW---------RGST 117
Query: 462 DFMETWRGLEDAQRMG*LKA-----SDCLTSTSSSWRGC*KKALSNLMLFK*RVTSKTFQ 626
ET GL+D Q+ G +K D + + +N +L+ + S++ +
Sbjct: 118 PLAETLEGLQDLQKEGLIKQYGVSNFDVDDMDQLTLEPGGDQIAANEVLY--NLQSRSIE 175
Query: 627 KEMVEFCQSESVVVMGYSPF 686
+++ + ++ +GYSPF
Sbjct: 176 YDLLPQQKQANITTIGYSPF 195
>UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 264
Score = 48.4 bits (110), Expect = 2e-04
Identities = 20/51 (39%), Positives = 34/51 (66%)
Frame = +3
Query: 273 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425
V + +KREDI++TTKL ++ + + +S+KKL + Y+DL+L+H P
Sbjct: 66 VRKSGLKREDIYVTTKLKPSEEGHSNALKYAKESIKKLDIGYVDLFLIHTP 116
Score = 39.5 bits (88), Expect = 0.079
Identities = 21/59 (35%), Positives = 31/59 (52%)
Frame = +1
Query: 79 MNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
+N+GR MP GLG + + DV + A+ GYR DTA +Y+ E+E+G
Sbjct: 15 LNDGRKMPLFGLGVF----------RLETGCEDVCLFALKNGYRMLDTADIYQNEKEVG 63
>UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3;
Saccharomycetales|Rep: Conjugated polyketone reductase
C1 - Candida parapsilosis (Yeast)
Length = 304
Score = 48.0 bits (109), Expect = 2e-04
Identities = 37/142 (26%), Positives = 65/142 (45%), Gaps = 10/142 (7%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQH-------RRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADY 446
+ R+D+FIT K + H + A+ L+ LGL+Y+DLYL+H+P ++
Sbjct: 75 LNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLGLEYVDLYLIHFP--YISEK 132
Query: 447 SHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALSNLMLFK*RVTSKTFQ 626
SH D +E WR LE A+ G + T + + ++ + S Q
Sbjct: 133 SHG-FDLVEAWRYLERAKNEGLARNIGVSNFTIENLKSILDANTDSIPVVNQIEFSAYLQ 191
Query: 627 KE---MVEFCQSESVVVMGYSP 683
+ +VE+ Q + +++ Y P
Sbjct: 192 DQTPGIVEYSQQQGILIEAYGP 213
Score = 46.0 bits (104), Expect = 0.001
Identities = 23/60 (38%), Positives = 34/60 (56%)
Frame = +1
Query: 76 KMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255
K++NG +PA+ GT + + G DKQL + A+ G+RH D A +Y T +EIG
Sbjct: 9 KLSNGNKIPAVAFGTGTKYFKRGH-NDLDKQLIGTLELALRSGFRHIDGAEIYGTNKEIG 67
>UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 303
Score = 48.0 bits (109), Expect = 2e-04
Identities = 26/62 (41%), Positives = 33/62 (53%)
Frame = +1
Query: 73 LKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252
LKM++G +P GLG Y + DK+ D V A++ GYRH DTA YE E
Sbjct: 33 LKMHDGNAIPQFGLGVY---------EMNDKETYDCVKWALEAGYRHVDTAEWYENEAPC 83
Query: 253 GK 258
GK
Sbjct: 84 GK 85
Score = 46.0 bits (104), Expect = 0.001
Identities = 29/76 (38%), Positives = 39/76 (51%)
Frame = +3
Query: 294 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFME 473
RE+IF+T+KL N + SLK+ G++Y DLYLMH IG V
Sbjct: 98 REEIFLTSKLKNNSSYEQAFVD-LKGSLKRSGVEYFDLYLMHSAIG-------GPVIRKN 149
Query: 474 TWRGLEDAQRMG*LKA 521
W+ L DAQ G +K+
Sbjct: 150 VWKALCDAQSQGLVKS 165
>UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1;
Klebsiella pneumoniae|Rep: Putative uncharacterized
protein - Klebsiella pneumoniae
Length = 279
Score = 47.6 bits (108), Expect = 3e-04
Identities = 18/47 (38%), Positives = 32/47 (68%)
Frame = +3
Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428
V RE +FIT+K+ + N++L++LG++Y++L+L+HWPI
Sbjct: 65 VPREQLFITSKIRGRDMGYARTLVSFNETLERLGVEYLELFLIHWPI 111
Score = 39.1 bits (87), Expect = 0.10
Identities = 21/67 (31%), Positives = 36/67 (53%)
Frame = +1
Query: 58 MEVPSLKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237
M S+ +N+G MP G G +L + ++D + ++ +A+ G+RHFDTA Y
Sbjct: 1 MTTDSILLNDGYYMPRPGCGLWL-------IDNRD--VDSLIRQALKAGFRHFDTAQAYF 51
Query: 238 TEQEIGK 258
E +G+
Sbjct: 52 NEDGVGR 58
Score = 36.3 bits (80), Expect = 0.74
Identities = 14/37 (37%), Positives = 26/37 (70%)
Frame = +2
Query: 500 ANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
A+G+++ IG+SNF Q +ER++++ + P Q+E H
Sbjct: 129 ASGLIRSIGVSNFTCQHIERLIEDTGVVPAVNQLELH 165
>UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 282
Score = 47.6 bits (108), Expect = 3e-04
Identities = 21/46 (45%), Positives = 32/46 (69%)
Frame = +3
Query: 294 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431
R++IF+ TKLW + R A A+ ++L++LG DYIDL ++H P G
Sbjct: 65 RDEIFLETKLWPSFFER---ASAVEETLERLGTDYIDLMILHQPAG 107
Score = 38.7 bits (86), Expect = 0.14
Identities = 23/62 (37%), Positives = 34/62 (54%)
Frame = +1
Query: 73 LKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252
+ +NNG +P +GLGTYL ++ D Q V A+D Y DTA+VY E+ +
Sbjct: 4 ITLNNGITIPQVGLGTYL-------LEPDDAQ--SAVTYALDNDYTLIDTANVYVNERAV 54
Query: 253 GK 258
G+
Sbjct: 55 GR 56
Score = 34.3 bits (75), Expect = 3.0
Identities = 15/35 (42%), Positives = 22/35 (62%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGH 610
G ++ IGLSNF+ Q +R+L E + P Q+E H
Sbjct: 123 GKIRAIGLSNFDVAQTQRILDECEVVPTINQVECH 157
>UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9;
Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 316
Score = 47.6 bits (108), Expect = 3e-04
Identities = 23/62 (37%), Positives = 35/62 (56%)
Frame = +1
Query: 73 LKMNNGRXMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252
+ NG MPA+G GT+ ++ D+++ + A++ GYRH DTA VY E+ I
Sbjct: 7 ITFENGTTMPALGFGTW---------RASDEEVEKALNEALEAGYRHIDTAPVYLNEKTI 57
Query: 253 GK 258
GK
Sbjct: 58 GK 59
Score = 45.2 bits (102), Expect = 0.002
Identities = 18/36 (50%), Positives = 27/36 (75%)
Frame = +2
Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEGHL 613
G+ + IGLSNFN++Q++R+L IKP +QIE H+
Sbjct: 154 GLARNIGLSNFNQRQIQRILDNCQIKPANLQIENHI 189
Score = 44.8 bits (101), Expect = 0.002
Identities = 40/163 (24%), Positives = 75/163 (46%), Gaps = 15/163 (9%)
Frame = +3
Query: 255 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI-- 428
+ +K ++ G V R+++FI TKL R + V + + +SL L L+Y+DLY +H P
Sbjct: 59 KVLKEWMDAGKVTRDELFIVTKLPPHGTRASTVEKFLKNSLDDLQLEYVDLYHVHVPFTV 118
Query: 429 -GLNADYSHSD--------VDFMETWRGLEDAQRMG*LKASDCLTSTSSSWRGC*KKALS 581
++ + D D + W+ +E+ G L + L++ + ++ L
Sbjct: 119 PEVDGPFLVEDGLIVLETTTDHVALWKAMEEVYEAG-LARNIGLSNFNQRQI---QRILD 174
Query: 582 NLMLFK*RVTSKTF----QKEMVEFCQSESVVVMGYSPFRFPG 698
N + + + Q E+V+FC++ + V YSP G
Sbjct: 175 NCQIKPANLQIENHIYLQQPELVKFCKANGITVTAYSPLGSKG 217
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 737,664,645
Number of Sequences: 1657284
Number of extensions: 15015439
Number of successful extensions: 41428
Number of sequences better than 10.0: 472
Number of HSP's better than 10.0 without gapping: 38964
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 41021
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 56611575523
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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