Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= e96h0880
(694 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 224 1e-57
UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 133 3e-30
UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 127 3e-28
UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 124 3e-27
UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 122 1e-26
UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 121 1e-26
UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 121 1e-26
UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 119 6e-26
UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 118 1e-25
UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 117 2e-25
UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 115 1e-24
UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 113 5e-24
UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 112 9e-24
UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 111 1e-23
UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 111 2e-23
UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 111 2e-23
UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 110 3e-23
UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 108 1e-22
UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 106 4e-22
UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 98 5e-22
UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 98 5e-22
UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 105 8e-22
UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 103 4e-21
UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 103 5e-21
UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 102 7e-21
UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 102 7e-21
UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 102 7e-21
UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 102 7e-21
UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 102 1e-20
UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 101 1e-20
UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 101 2e-20
UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 101 2e-20
UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 101 2e-20
UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 100 3e-20
UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 100 3e-20
UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 100 3e-20
UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 100 3e-20
UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 99 5e-20
UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 99 5e-20
UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 100 7e-20
UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 99 9e-20
UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 99 9e-20
UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 99 9e-20
UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 99 1e-19
UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 99 1e-19
UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 98 2e-19
UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 98 2e-19
UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 98 2e-19
UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 97 3e-19
UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 97 4e-19
UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 97 4e-19
UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 97 4e-19
UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 97 4e-19
UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 97 5e-19
UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 97 5e-19
UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 97 5e-19
UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 96 6e-19
UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 96 8e-19
UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 96 8e-19
UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 95 1e-18
UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 95 1e-18
UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 95 1e-18
UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 95 1e-18
UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 95 2e-18
UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 95 2e-18
UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 95 2e-18
UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 94 3e-18
UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 94 3e-18
UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 94 3e-18
UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 94 3e-18
UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 93 4e-18
UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 93 4e-18
UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 93 4e-18
UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 93 4e-18
UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 93 6e-18
UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 93 6e-18
UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 93 6e-18
UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 93 8e-18
UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 93 8e-18
UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 93 8e-18
UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 92 1e-17
UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 92 1e-17
UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 92 1e-17
UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 92 1e-17
UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 91 2e-17
UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 91 2e-17
UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 91 2e-17
UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 91 3e-17
UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 90 4e-17
UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 90 4e-17
UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 90 4e-17
UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 90 4e-17
UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 89 7e-17
UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 89 7e-17
UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 89 1e-16
UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 89 1e-16
UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 89 1e-16
UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 89 1e-16
UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 88 2e-16
UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 88 2e-16
UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 88 2e-16
UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 87 3e-16
UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 87 4e-16
UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 87 4e-16
UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 87 5e-16
UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 87 5e-16
UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 87 5e-16
UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 86 9e-16
UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 86 9e-16
UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 85 1e-15
UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 85 1e-15
UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 85 1e-15
UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 85 2e-15
UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 85 2e-15
UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 85 2e-15
UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 84 3e-15
UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 84 4e-15
UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 84 4e-15
UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 83 5e-15
UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 83 5e-15
UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 83 5e-15
UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 83 8e-15
UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 83 8e-15
UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 83 8e-15
UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 83 8e-15
UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 83 8e-15
UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 83 8e-15
UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 83 8e-15
UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 82 1e-14
UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 82 1e-14
UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 81 2e-14
UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 81 2e-14
UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 81 3e-14
UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 81 3e-14
UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 81 3e-14
UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 80 4e-14
UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 80 4e-14
UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 80 4e-14
UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 80 4e-14
UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 79 8e-14
UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 79 8e-14
UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 79 8e-14
UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 79 8e-14
UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 79 1e-13
UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 79 1e-13
UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 79 1e-13
UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 79 1e-13
UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 78 2e-13
UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 78 2e-13
UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 78 2e-13
UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 78 2e-13
UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 78 2e-13
UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 78 2e-13
UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 77 3e-13
UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;... 77 4e-13
UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 77 4e-13
UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 77 4e-13
UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 77 4e-13
UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 77 4e-13
UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 77 4e-13
UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 77 5e-13
UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 77 5e-13
UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 77 5e-13
UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 77 5e-13
UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 77 5e-13
UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 76 7e-13
UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 76 7e-13
UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 76 7e-13
UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 76 1e-12
UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 76 1e-12
UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 76 1e-12
UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 76 1e-12
UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 75 1e-12
UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 75 1e-12
UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 75 1e-12
UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 75 1e-12
UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 75 2e-12
UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 75 2e-12
UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc... 75 2e-12
UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 75 2e-12
UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 75 2e-12
UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 74 3e-12
UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 74 3e-12
UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 74 4e-12
UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 74 4e-12
UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 74 4e-12
UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 73 5e-12
UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 73 5e-12
UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 73 5e-12
UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 73 7e-12
UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 73 7e-12
UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 73 7e-12
UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 73 7e-12
UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 73 9e-12
UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 73 9e-12
UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 73 9e-12
UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 73 9e-12
UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 72 1e-11
UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 72 1e-11
UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 72 2e-11
UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 72 2e-11
UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 72 2e-11
UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 71 2e-11
UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 71 2e-11
UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 71 2e-11
UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 71 2e-11
UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 71 2e-11
UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 69 8e-11
UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 69 8e-11
UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 69 1e-10
UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 68 2e-10
UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 68 2e-10
UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 68 2e-10
UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 68 3e-10
UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 68 3e-10
UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 68 3e-10
UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 67 3e-10
UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 67 3e-10
UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 67 3e-10
UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 67 4e-10
UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 67 4e-10
UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 67 4e-10
UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 66 6e-10
UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 66 6e-10
UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 66 8e-10
UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap... 66 8e-10
UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 66 8e-10
UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 66 1e-09
UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 66 1e-09
UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 66 1e-09
UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 65 2e-09
UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 64 2e-09
UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 64 2e-09
UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 64 2e-09
UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 64 3e-09
UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 64 3e-09
UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 64 3e-09
UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 64 3e-09
UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 64 3e-09
UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 64 3e-09
UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 64 4e-09
UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 64 4e-09
UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 63 5e-09
UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 63 5e-09
UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 63 7e-09
UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 63 7e-09
UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 62 9e-09
UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 62 9e-09
UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 62 1e-08
UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 62 1e-08
UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 62 1e-08
UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 62 2e-08
UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 61 2e-08
UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 61 2e-08
UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 61 2e-08
UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 60 4e-08
UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 60 4e-08
UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 60 4e-08
UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 60 5e-08
UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 60 5e-08
UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 60 5e-08
UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|... 60 5e-08
UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 60 7e-08
UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 60 7e-08
UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 59 9e-08
UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 59 9e-08
UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 59 9e-08
UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 59 9e-08
UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 59 9e-08
UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 59 9e-08
UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 59 1e-07
UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 59 1e-07
UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 59 1e-07
UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 58 2e-07
UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 58 3e-07
UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 57 4e-07
UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 57 5e-07
UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ... 57 5e-07
UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 56 6e-07
UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 56 8e-07
UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 56 8e-07
UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 56 8e-07
UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 56 1e-06
UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei... 55 1e-06
UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 55 1e-06
UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 55 1e-06
UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 55 2e-06
UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 55 2e-06
UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto... 54 3e-06
UniRef50_A0QWF1 Cluster: Aldo/keto reductase; n=1; Mycobacterium... 54 3e-06
UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 54 3e-06
UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 54 3e-06
UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 54 4e-06
UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|... 53 8e-06
UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 53 8e-06
UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ... 53 8e-06
UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 53 8e-06
UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 52 1e-05
UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere... 52 1e-05
UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 52 1e-05
UniRef50_A1ZPI5 Cluster: Oxidoreductase; n=1; Microscilla marina... 52 1e-05
UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 52 1e-05
UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 52 2e-05
UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 52 2e-05
UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ... 51 2e-05
UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel... 51 3e-05
UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter... 51 3e-05
UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy... 51 3e-05
UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 51 3e-05
UniRef50_Q6CI80 Cluster: Similar to tr|O59826 Schizosaccharomyce... 51 3e-05
UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 51 3e-05
UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;... 50 4e-05
UniRef50_Q97UG6 Cluster: Oxidoreductase; n=5; Archaea|Rep: Oxido... 50 4e-05
UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 50 5e-05
UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 50 5e-05
UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular organis... 50 7e-05
UniRef50_A6WAE5 Cluster: Aldo/keto reductase; n=1; Kineococcus r... 50 7e-05
UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ... 50 7e-05
UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 50 7e-05
UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 50 7e-05
UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 49 9e-05
UniRef50_A6LWU9 Cluster: Aldo/keto reductase; n=3; Clostridium|R... 49 9e-05
UniRef50_A5CYR4 Cluster: Predicted oxidoreductases; n=2; Clostri... 49 9e-05
UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 49 9e-05
UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 49 1e-04
UniRef50_P77735 Cluster: Uncharacterized oxidoreductase yajO; n=... 49 1e-04
UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 48 2e-04
UniRef50_A0K203 Cluster: Aldo/keto reductase; n=2; Arthrobacter|... 48 2e-04
UniRef50_P80874 Cluster: General stress protein 69; n=16; cellul... 48 2e-04
UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep... 48 2e-04
UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3.... 48 2e-04
UniRef50_Q2FGN2 Cluster: Oxidoreductase, aldo/keto reductase fam... 48 3e-04
UniRef50_Q02C17 Cluster: Aldo/keto reductase precursor; n=1; Sol... 48 3e-04
UniRef50_A0YSM3 Cluster: Probable oxidoreductase; n=1; Lyngbya s... 48 3e-04
UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 48 3e-04
UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom... 48 3e-04
UniRef50_A1DD54 Cluster: Aldo/keto reductase; n=3; Trichocomacea... 48 3e-04
UniRef50_P49261 Cluster: Rho beta-crystallin; n=1; Lepidodactylu... 48 3e-04
UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 48 3e-04
UniRef50_Q1EZH4 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 47 4e-04
UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ... 47 4e-04
UniRef50_Q0SJ60 Cluster: Possible aldo/keto reductase; n=50; Bac... 47 5e-04
UniRef50_Q837G5 Cluster: Oxidoreductase, aldo/keto reductase 2 f... 46 7e-04
UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 46 7e-04
UniRef50_Q2J7H2 Cluster: Aldo/keto reductase; n=16; Bacteria|Rep... 46 7e-04
UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 46 7e-04
UniRef50_A0Y7Y8 Cluster: Aldo/keto reductase; n=1; marine gamma ... 46 7e-04
UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 46 7e-04
UniRef50_Q0LKQ4 Cluster: Aldo/keto reductase; n=1; Herpetosiphon... 46 9e-04
UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia... 46 9e-04
UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga... 46 9e-04
UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 46 9e-04
UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 46 0.001
UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy... 46 0.001
UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact... 46 0.001
UniRef50_A3H9H5 Cluster: Aldo/keto reductase; n=2; Archaea|Rep: ... 46 0.001
UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 46 0.001
UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 45 0.002
UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 45 0.002
UniRef50_Q8YXI8 Cluster: All1225 protein; n=9; Cyanobacteria|Rep... 45 0.002
UniRef50_Q8YAN3 Cluster: Lmo0084 protein; n=11; Listeria monocyt... 45 0.002
UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 45 0.002
UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ... 45 0.002
UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ... 45 0.002
UniRef50_Q82JL9 Cluster: Putative oxidoreductase; n=2; Streptomy... 44 0.003
UniRef50_Q7NCE7 Cluster: Glr3032 protein; n=5; Cyanobacteria|Rep... 44 0.003
UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 44 0.003
UniRef50_A1SCW7 Cluster: Aldo/keto reductase; n=2; Actinomycetal... 44 0.003
UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 44 0.003
UniRef50_Q46851 Cluster: Uncharacterized protein yghZ; n=126; Ba... 44 0.003
UniRef50_UPI0000447325 Cluster: PREDICTED: similar to aldo-keto ... 44 0.004
UniRef50_O59826 Cluster: Potassium channel subunit; n=9; cellula... 44 0.004
UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000... 44 0.005
UniRef50_A5UXT4 Cluster: Aldo/keto reductase; n=2; Roseiflexus|R... 44 0.005
UniRef50_A0RWV1 Cluster: Oxidoreductase; n=4; Thermoprotei|Rep: ... 44 0.005
UniRef50_UPI00015BB020 Cluster: aldo/keto reductase; n=1; Ignico... 43 0.006
UniRef50_Q9X0R5 Cluster: Oxidoreductase, aldo/keto reductase fam... 43 0.006
UniRef50_Q67NQ1 Cluster: Oxidoreductase; n=1; Symbiobacterium th... 43 0.006
UniRef50_Q099T4 Cluster: Oxidoreductase; n=2; Proteobacteria|Rep... 43 0.006
UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 43 0.006
UniRef50_A5VEK4 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 43 0.006
UniRef50_A0Q648 Cluster: Aldo/keto reductase family protein; n=1... 43 0.006
UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 43 0.006
UniRef50_Q88TP1 Cluster: Oxidoreductase; n=3; Bacteria|Rep: Oxid... 43 0.008
UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 43 0.008
UniRef50_Q7D3N9 Cluster: AGR_pAT_274p; n=3; Proteobacteria|Rep: ... 43 0.008
UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 43 0.008
UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=... 43 0.008
UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular... 42 0.011
UniRef50_Q6XUT6 Cluster: Oxido-reductase/dehydratase; n=3; Bacte... 42 0.011
UniRef50_A6E9U0 Cluster: Oxidoreductase; n=1; Pedobacter sp. BAL... 42 0.011
UniRef50_A0JVH3 Cluster: Aldo/keto reductase; n=17; Bacteria|Rep... 42 0.011
UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ... 42 0.011
UniRef50_Q97UJ7 Cluster: Oxidoreductase; n=4; Archaea|Rep: Oxido... 42 0.011
UniRef50_P0A9T5 Cluster: Protein tas; n=88; Bacteria|Rep: Protei... 42 0.011
UniRef50_Q49V75 Cluster: Putative oxidoreductase; n=1; Staphyloc... 42 0.014
UniRef50_Q1IXM8 Cluster: Aldo/keto reductase; n=2; Bacteria|Rep:... 42 0.014
UniRef50_A6FYX9 Cluster: Oxidoreductase; n=1; Plesiocystis pacif... 42 0.014
UniRef50_A3TNI0 Cluster: Oxidoreductase, aldo/keto reductase fam... 42 0.014
UniRef50_A1GCG3 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 42 0.014
UniRef50_A0UWW6 Cluster: Aldo/keto reductase; n=1; Clostridium c... 42 0.014
UniRef50_Q23TY7 Cluster: Oxidoreductase, aldo/keto reductase fam... 42 0.014
UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 42 0.014
UniRef50_Q94A68 Cluster: Uncharacterized oxidoreductase At1g0669... 42 0.014
UniRef50_UPI0000D9C1BD Cluster: PREDICTED: similar to aldo-keto ... 42 0.019
UniRef50_Q13GB1 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 42 0.019
UniRef50_Q0BAM8 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 42 0.019
UniRef50_A6CMV7 Cluster: Putative uncharacterized protein; n=2; ... 42 0.019
UniRef50_A3H7G3 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 42 0.019
UniRef50_UPI00003C85A8 Cluster: hypothetical protein Faci_030001... 41 0.025
UniRef50_Q034L5 Cluster: Aryl-alcohol dehydrogenase related enzy... 41 0.025
UniRef50_A6VXU3 Cluster: Aldo/keto reductase; n=14; Proteobacter... 41 0.025
UniRef50_A5FGY2 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 41 0.025
UniRef50_Q701X7 Cluster: Putative uncharacterized protein; n=1; ... 41 0.025
UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase... 41 0.033
UniRef50_Q7VG62 Cluster: Aldo-keto reductase; n=2; Helicobacter|... 41 0.033
UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 41 0.033
UniRef50_Q3I1P2 Cluster: Aldo-keto oxidoreductase; n=6; Bacteria... 41 0.033
UniRef50_Q097V7 Cluster: MocA; n=1; Stigmatella aurantiaca DW4/3... 41 0.033
UniRef50_A1SLH1 Cluster: Aldo/keto reductase; n=27; Bacteria|Rep... 41 0.033
UniRef50_Q2NEM6 Cluster: Putative oxidoreductase; n=1; Methanosp... 41 0.033
UniRef50_P54569 Cluster: Uncharacterized oxidoreductase yqkF; n=... 41 0.033
UniRef50_Q09923 Cluster: Aldo-keto reductase yakc [NADP+]; n=13;... 41 0.033
UniRef50_Q1PBI2 Cluster: L-galactose dehydrogenase; n=15; Magnol... 40 0.044
UniRef50_Q8EZ83 Cluster: Aldo/keto reductase family protein; n=1... 40 0.058
UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 40 0.058
UniRef50_Q27ST7 Cluster: Oxidoreductase; n=2; Eukaryota|Rep: Oxi... 40 0.058
UniRef50_Q7S6W9 Cluster: Putative uncharacterized protein NCU055... 40 0.058
UniRef50_Q40648 Cluster: Probable voltage-gated potassium channe... 40 0.058
UniRef50_UPI0001556575 Cluster: PREDICTED: similar to Aldo-keto ... 40 0.076
UniRef50_Q38Z15 Cluster: Putative aldo/keto reductase; n=2; Bact... 40 0.076
UniRef50_Q74DE6 Cluster: Oxidoreductase, aldo/keto reductase fam... 39 0.10
UniRef50_Q31SB1 Cluster: Putative uncharacterized protein; n=2; ... 39 0.10
UniRef50_Q2SL81 Cluster: Predicted oxidoreductase; n=10; Bacteri... 39 0.10
UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria... 39 0.10
UniRef50_Q12D62 Cluster: Aldo/keto reductase; n=12; Proteobacter... 39 0.10
UniRef50_A0ZMD5 Cluster: Tas; n=1; Nodularia spumigena CCY 9414|... 39 0.10
UniRef50_Q5K825 Cluster: Aryl-alcohol dehydrogenase, putative; n... 39 0.10
UniRef50_Q5ASJ7 Cluster: Putative uncharacterized protein; n=1; ... 39 0.10
UniRef50_A6RNJ6 Cluster: Putative uncharacterized protein; n=1; ... 39 0.10
UniRef50_A5UNN5 Cluster: Predicted oxidoreductase, aldo/keto red... 39 0.10
UniRef50_Q0RGM0 Cluster: Putative aldoketoreductase; n=2; Franki... 39 0.13
UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep... 39 0.13
UniRef50_A0QHX8 Cluster: General stress protein 69; n=2; Mycobac... 39 0.13
UniRef50_Q9X123 Cluster: Oxidoreductase, putative; n=4; Bacteria... 38 0.18
UniRef50_Q97KZ9 Cluster: Fe-S oxidoreductase; n=6; cellular orga... 38 0.18
UniRef50_Q88SS2 Cluster: Oxidoreductase; n=13; Firmicutes|Rep: O... 38 0.18
UniRef50_Q7D001 Cluster: AGR_C_2023p; n=14; Proteobacteria|Rep: ... 38 0.18
UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:... 38 0.18
UniRef50_A7AFQ7 Cluster: Putative uncharacterized protein; n=1; ... 38 0.18
UniRef50_A6X3I0 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 38 0.18
UniRef50_A6EEC4 Cluster: Putative Norsolorinic acid reductase; n... 38 0.18
UniRef50_Q5V3K3 Cluster: Oxidoreductase aldo/keto reductase fami... 38 0.18
UniRef50_Q89JX0 Cluster: Oxidoreductase; n=26; Bacteria|Rep: Oxi... 38 0.23
UniRef50_Q88ZU3 Cluster: Oxidoreductase; n=1; Lactobacillus plan... 38 0.23
UniRef50_Q2J8X9 Cluster: Aldo/keto reductase; n=3; Frankia|Rep: ... 38 0.23
UniRef50_Q2AI49 Cluster: Aldo/keto reductase; n=1; Halothermothr... 38 0.23
UniRef50_Q022Y6 Cluster: Aldo/keto reductase precursor; n=2; Sol... 38 0.23
UniRef50_A6VX84 Cluster: Aldo/keto reductase; n=4; Gammaproteoba... 38 0.23
UniRef50_A1RA11 Cluster: Oxidoreductase, aldo/keto reductase fam... 38 0.23
UniRef50_A0UVR1 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 38 0.23
UniRef50_Q5V0P8 Cluster: Oxidoreductase; n=2; Halobacteriaceae|R... 38 0.23
UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose red... 38 0.31
UniRef50_Q81RN9 Cluster: Oxidoreductase, aldo/keto reductase fam... 38 0.31
UniRef50_Q5KYH6 Cluster: K+ channel beta subunit; n=5; Bacteria|... 38 0.31
UniRef50_Q04TM6 Cluster: Aryl-alcohol dehydrogenase-related oxid... 38 0.31
UniRef50_A7HER9 Cluster: Aldo/keto reductase; n=2; Anaeromyxobac... 38 0.31
UniRef50_Q39151 Cluster: K+ channel protein; n=29; cellular orga... 38 0.31
UniRef50_Q6L0T3 Cluster: Oxidoreductase; n=2; Thermoplasmatales|... 38 0.31
UniRef50_Q2NFN7 Cluster: Predicted oxidoreductase; n=1; Methanos... 38 0.31
UniRef50_P49249 Cluster: IN2-2 protein; n=6; Magnoliophyta|Rep: ... 38 0.31
UniRef50_Q64UJ6 Cluster: Putative aldo/keto reductase; n=3; Bact... 37 0.41
UniRef50_Q15JF3 Cluster: Putative oxidoreductase; n=1; Streptomy... 37 0.41
UniRef50_A7HAM2 Cluster: Aldo/keto reductase; n=9; cellular orga... 37 0.41
UniRef50_A6W292 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 37 0.41
UniRef50_A5V463 Cluster: Aldo/keto reductase; n=1; Sphingomonas ... 37 0.41
UniRef50_P93818 Cluster: F19P19.12 protein; n=4; Arabidopsis tha... 37 0.41
UniRef50_A0C161 Cluster: Chromosome undetermined scaffold_141, w... 37 0.41
UniRef50_Q2H7Q3 Cluster: Putative uncharacterized protein; n=1; ... 37 0.41
UniRef50_Q8TTK4 Cluster: Aldo/keto reductase; n=28; cellular org... 37 0.41
UniRef50_Q98IA6 Cluster: Aryl-alcohol dehydrogenase; n=1; Mesorh... 37 0.54
UniRef50_Q98EU0 Cluster: Oxidoreductase; MocA; n=27; Bacteria|Re... 37 0.54
UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta... 37 0.54
UniRef50_Q7NJD8 Cluster: Gll1894 protein; n=5; Bacteria|Rep: Gll... 37 0.54
UniRef50_Q6MHN8 Cluster: Potassium voltage-gated channel, shaker... 37 0.54
UniRef50_Q1IYI7 Cluster: Aldo/keto reductase; n=3; Deinococcus g... 37 0.54
UniRef50_A7HL79 Cluster: Aldo/keto reductase; n=1; Fervidobacter... 37 0.54
UniRef50_A7AFU4 Cluster: Putative uncharacterized protein; n=1; ... 37 0.54
UniRef50_Q016B0 Cluster: COG0667: Predicted oxidoreductases; n=4... 37 0.54
UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno... 37 0.54
UniRef50_Q7Q0Y6 Cluster: ENSANGP00000006086; n=7; Coelomata|Rep:... 37 0.54
UniRef50_Q97ZZ1 Cluster: Oxidoreductase; n=4; Sulfolobaceae|Rep:... 37 0.54
UniRef50_Q0W0V6 Cluster: Predicted aldo/keto reductase; n=2; Eur... 37 0.54
UniRef50_Q8F4Y9 Cluster: Aldo/keto reductase family protein; n=4... 36 0.71
UniRef50_Q3WFK9 Cluster: Aldo/keto reductase precursor; n=1; Fra... 36 0.71
UniRef50_Q1IXS0 Cluster: Putative aldehyde reductase; n=1; Deino... 36 0.71
UniRef50_Q1FGT0 Cluster: Aldo/keto reductase; n=1; Clostridium p... 36 0.71
UniRef50_Q11KU9 Cluster: Twin-arginine translocation pathway sig... 36 0.71
UniRef50_Q0FFB1 Cluster: Aldo/keto reductase; n=1; alpha proteob... 36 0.71
UniRef50_A4XIJ0 Cluster: Aldo/keto reductase; n=1; Caldicellulos... 36 0.71
>UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase
precursor; n=1; Spodoptera littoralis|Rep:
3-dehydroecdysone 3beta-reductase precursor - Spodoptera
littoralis (Egyptian cotton leafworm)
Length = 345
Score = 224 bits (548), Expect = 1e-57
Identities = 95/158 (60%), Positives = 127/158 (80%)
Frame = +2
Query: 44 ASTMEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTAS 223
++T++VP LKM N R+MPAI GTYLGFD+ G V SKDKQLR+VVM+AID+G RHFDTA+
Sbjct: 17 SATIDVPMLKMLNDREMPAIALGTYLGFDKGGAVTSKDKQLRNVVMQAIDLGYRHFDTAA 76
Query: 224 VYETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDL 403
+Y TE ++MK++EGV+KRED+F+TTKLWNT H+R +VA A+ ++L K GLDY+DL
Sbjct: 77 IYNTEAEVGEAIRMKIDEGVIKREDVFLTTKLWNTHHKREQVAVAMKETLNKTGLDYVDL 136
Query: 404 YLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
+LMHWPI LN DYSHS+ D++ETWR E+ ++G K+
Sbjct: 137 FLMHWPIALNEDYSHSNTDYLETWRATEEMVKLGYTKS 174
Score = 53.2 bits (122), Expect = 6e-06
Identities = 25/41 (60%), Positives = 31/41 (75%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSKTFRK 624
GY K IGLSNFNK Q+ VL+E TIKP A+QIEVH + ++
Sbjct: 170 GYTKSIGLSNFNKLQVATVLQECTIKPVALQIEVHPQIIQE 210
>UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
GA10458-PA - Nasonia vitripennis
Length = 569
Score = 133 bits (322), Expect = 3e-30
Identities = 67/166 (40%), Positives = 95/166 (57%), Gaps = 11/166 (6%)
Frame = +2
Query: 53 MEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYE 232
M VP++ N+G MP IG GT+L SK ++ + V AI+VG RH DTA YE
Sbjct: 1 MPVPTVTFNDGYKMPMIGLGTFL---------SKPGEVAEAVKYAIEVGYRHVDTAFFYE 51
Query: 233 TETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 412
E ++ K+ +G +KREDIF+TTKLW H+ EV A SL+ LG DYIDL+L+
Sbjct: 52 NEKEIGSAIREKINDGTIKREDIFVTTKLWCNSHKEDEVVPACKKSLENLGFDYIDLFLV 111
Query: 413 HWPIGLNA-----------DYSHSDVDFMETWRGLEDAQRMGILKA 517
HWP + SD D++ETW+G+E+ +R G+ ++
Sbjct: 112 HWPFAFKSGDALTPRDAAGKIEFSDTDYLETWKGMEECKRQGLARS 157
Score = 106 bits (255), Expect = 4e-22
Identities = 49/113 (43%), Positives = 71/113 (62%), Gaps = 8/113 (7%)
Frame = +2
Query: 203 RHFDTASVYETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKL 382
RH DTA +Y+ E ++ K+++G VKRED+F+TTKL H+ +EV A SL L
Sbjct: 302 RHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVTTKLSYYAHKESEVVPACKQSLNDL 361
Query: 383 GLDYIDLYLMHWPI--------GLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
GLDYIDLYL+HWPI + SD D++ETW+G+E+ +R G+ ++
Sbjct: 362 GLDYIDLYLIHWPIRRYFRHNKNASGKLLLSDTDYLETWKGMEECKRQGLARS 414
Score = 41.5 bits (93), Expect = 0.019
Identities = 19/45 (42%), Positives = 27/45 (60%)
Frame = +1
Query: 490 CSANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSKTFRK 624
C G + IG+SNFN +Q+ R+L+ IKP Q+EV K +K
Sbjct: 406 CKRQGLARSIGVSNFNSEQITRLLEAAKIKPVNNQVEVSLKLNQK 450
Score = 41.1 bits (92), Expect = 0.025
Identities = 18/38 (47%), Positives = 23/38 (60%)
Frame = +1
Query: 490 CSANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEV 603
C G + IGLSNFN +Q+ R+L IKP Q+EV
Sbjct: 149 CKRQGLARSIGLSNFNSEQIARLLSSAKIKPVNNQVEV 186
>UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1;
Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase -
Trichoplusia ni (Cabbage looper)
Length = 308
Score = 127 bits (306), Expect = 3e-28
Identities = 60/154 (38%), Positives = 99/154 (64%)
Frame = +2
Query: 56 EVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYET 235
+ P ++N+G +P++ GT+ GF G + ++R V+ AI G RH DTA++Y
Sbjct: 23 KAPLKQLNDGNAIPSLALGTF-GF---GDIP----KVRQAVLWAIQAGYRHIDTAALYGN 74
Query: 236 ETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 415
E + + +++G+VKRE++F+TTKLWN +H R +V A+ +SL KLGL Y+DLYL+H
Sbjct: 75 EEEVGKGIADAIQQGLVKREELFVTTKLWNDKHGRHQVVPALRESLTKLGLSYVDLYLIH 134
Query: 416 WPIGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
P N + D+D + TW G+E+A+++G+ K+
Sbjct: 135 SPEATNENGDPVDIDVLNTWNGMEEAKKLGLAKS 168
Score = 33.9 bits (74), Expect = 3.8
Identities = 19/42 (45%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH-SKTFRK 624
G K IG+SNF+ L+R++ P QIEVH SKT K
Sbjct: 164 GLAKSIGVSNFDTALLDRLIAGSNTVPAVNQIEVHPSKTQEK 205
>UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 321
Score = 124 bits (298), Expect = 3e-27
Identities = 61/165 (36%), Positives = 97/165 (58%), Gaps = 11/165 (6%)
Frame = +2
Query: 56 EVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYET 235
+V + +++G +P +G GT+ G + ++ + V AID G RHFD AS Y
Sbjct: 4 KVDEITLSDGNKVPVLGLGTWQGGND-------PDEVENAVKLAIDAGYRHFDCASFYGN 56
Query: 236 ETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 415
E + ++ K+++GVVKRED+F+ TK+WN + ++ V A SLKKLGL YIDLYL+H
Sbjct: 57 EAEIGKAIQEKIDQGVVKREDLFVVTKVWNDERKQELVVAACKRSLKKLGLGYIDLYLVH 116
Query: 416 WPIGLNADYSH-----------SDVDFMETWRGLEDAQRMGILKA 517
WP Y + +VD++ETWRG+E+ ++G+ ++
Sbjct: 117 WPFSYPILYQYIVLPTYNAVTLDEVDYIETWRGMEECIKLGLTRS 161
Score = 47.6 bits (108), Expect = 3e-04
Identities = 24/54 (44%), Positives = 32/54 (59%)
Frame = +1
Query: 490 CSANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSKTFRKKWWNFVSLK 651
C G + IG+SNFN QQL R+L+ +IKP QIE+H +KK F + K
Sbjct: 153 CIKLGLTRSIGVSNFNSQQLTRLLESASIKPVMNQIELHINLNQKKLREFCASK 206
>UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep:
GA19341-PA - Drosophila pseudoobscura (Fruit fly)
Length = 315
Score = 122 bits (293), Expect = 1e-26
Identities = 61/167 (36%), Positives = 96/167 (57%), Gaps = 12/167 (7%)
Frame = +2
Query: 53 MEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYE 232
M PS +++GR+MP +G GT+ +S + + V AID+G RHFD A +Y
Sbjct: 1 MSTPSFLLSSGRNMPMVGLGTW---------RSPPEVVAQAVKDAIDIGYRHFDCAHIYG 51
Query: 233 TETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 412
E ++ K++EG+V R+++FIT+KLWNT H+ V A SL+ LG+DY+DLYLM
Sbjct: 52 NELHVGVAIREKIQEGLVTRDELFITSKLWNTFHKPELVRAACETSLRNLGIDYLDLYLM 111
Query: 413 HWPIGLNADYS------------HSDVDFMETWRGLEDAQRMGILKA 517
HWP+ + + D+D+++TW+ +ED G++ A
Sbjct: 112 HWPMAYKSGDNLYPTCPDTGKAVFEDIDYLDTWKAMEDLVDSGLVNA 158
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/36 (44%), Positives = 25/36 (69%)
Frame = +1
Query: 499 NGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
+G + IG+SNFN++Q+ R+L +KP +QIE H
Sbjct: 153 SGLVNAIGVSNFNEKQINRLLCLAKLKPVMLQIECH 188
>UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p -
Drosophila melanogaster (Fruit fly)
Length = 311
Score = 121 bits (292), Expect = 1e-26
Identities = 61/160 (38%), Positives = 94/160 (58%), Gaps = 8/160 (5%)
Frame = +2
Query: 62 PSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETET 241
P++++NNGR+MP +G GT+ F+ + ++ A+DVG RH DTA VYE E
Sbjct: 6 PTIRLNNGREMPTLGLGTWKSFESDAYHSTR---------HALDVGYRHLDTAFVYENEA 56
Query: 242 RNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 421
+ + K+ EGVV RE++F+TTKL H V +A SL LGL+Y+DLYLMH P
Sbjct: 57 EVGQAISEKIAEGVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMP 116
Query: 422 IG--------LNADYSHSDVDFMETWRGLEDAQRMGILKA 517
+G ++ +DVD+++TWR +E +G+ ++
Sbjct: 117 VGQKFHNDSNVHGTLELTDVDYLDTWREMEKLVDLGLTRS 156
Score = 37.9 bits (84), Expect = 0.23
Identities = 18/35 (51%), Positives = 21/35 (60%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G + IGLSNFN Q ERVL I+P Q+E H
Sbjct: 152 GLTRSIGLSNFNAAQTERVLANCRIRPVVNQVECH 186
>UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep:
Aldo-keto reductase - Aedes aegypti (Yellowfever
mosquito)
Length = 324
Score = 121 bits (292), Expect = 1e-26
Identities = 68/164 (41%), Positives = 91/164 (55%), Gaps = 15/164 (9%)
Frame = +2
Query: 59 VPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETE 238
+P++K+NNG +MPAIG GT + SK + VM AID G RH DTA Y E
Sbjct: 6 IPTVKLNNGLEMPAIGLGTSM---------SKGDECCKAVMTAIDEGFRHIDTAYNYRNE 56
Query: 239 TRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 418
R ++ K+EEGVV RE++F+TTKLWNT H V A SL+ LGLDY+DL+L+H
Sbjct: 57 DVVGRAIRAKIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSLEHLGLDYVDLFLIHM 116
Query: 419 PIGL---------------NADYSHSDVDFMETWRGLEDAQRMG 505
P G N + SD D+++TW+ +E G
Sbjct: 117 PFGYEFNGWDPEKRTPLDDNGNVLCSDDDYVDTWKAMEKLLESG 160
Score = 39.5 bits (88), Expect = 0.076
Identities = 17/42 (40%), Positives = 27/42 (64%)
Frame = +1
Query: 499 NGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSKTFRK 624
+G + IG+SNFN +QLER+L +KP Q+E ++ +K
Sbjct: 159 SGRVHSIGVSNFNSEQLERILANCRVKPVTNQVECSARINQK 200
>UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae
str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae
str. PEST
Length = 319
Score = 119 bits (287), Expect = 6e-26
Identities = 64/159 (40%), Positives = 96/159 (60%), Gaps = 15/159 (9%)
Frame = +2
Query: 56 EVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYET 235
+VP+++ +NG ++P +G GTYL Q G Q ++V +AID+G RH DTA +YE
Sbjct: 4 QVPTVRFSNGYEIPVLGYGTYLA--QKG-------QCVELVKKAIDLGYRHIDTAFLYEN 54
Query: 236 ETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 415
E + ++ K+ EGV++RED+F+TTKLWNT H V +A S L + YIDL+LMH
Sbjct: 55 EVEIGQAIRDKIAEGVIRREDVFVTTKLWNTFHDPQHVEEAFRRSFDMLDIGYIDLFLMH 114
Query: 416 WPIGLN-ADYSH--------------SDVDFMETWRGLE 487
P+G+ + Y + SDVD++ETW+ +E
Sbjct: 115 SPMGVQFSGYEYADMQPKDAAGNMLFSDVDYVETWKAME 153
Score = 44.4 bits (100), Expect = 0.003
Identities = 18/38 (47%), Positives = 28/38 (73%)
Frame = +1
Query: 493 SANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
+A G ++ IGLSNFN +Q+ER+L+ T+KP Q+E +
Sbjct: 157 TAGGRVRSIGLSNFNSEQIERILQIATVKPVNNQVEAN 194
>UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13;
n=11; Theria|Rep: Aldo-keto reductase family 1 member
C13 - Mus musculus (Mouse)
Length = 323
Score = 118 bits (285), Expect = 1e-25
Identities = 67/161 (41%), Positives = 97/161 (60%), Gaps = 11/161 (6%)
Frame = +2
Query: 68 LKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRN 247
+K+N+G +PA+G GTY V KSK + A+DVG RH DTA Y+ E
Sbjct: 8 VKLNDGHLIPALGFGTY---KPKEVPKSKSLE---AACLALDVGYRHVDTAYAYQVEEEI 61
Query: 248 WRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 427
+ ++ K++ GVVKRED+FITTKLW T R V A+ SLKKL LDY+DLY+MH+P+
Sbjct: 62 GQAIQSKIKAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVP 121
Query: 428 LNA---DYSHSD--------VDFMETWRGLEDAQRMGILKA 517
+ + D+ ++ VDF +TW LE+ + G++K+
Sbjct: 122 MKSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKS 162
Score = 42.7 bits (96), Expect = 0.008
Identities = 24/60 (40%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
Frame = +1
Query: 478 RIGRCSANGYIKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHSKTFRKKWWNFVSLK 651
R+ C G +K IG+SNFN +QLER+L K G KP Q+E H ++K ++ K
Sbjct: 150 RLEECKDAGLVKSIGVSNFNHRQLERILNKPGLKYKPVCNQVECHLYLNQRKLLDYCESK 209
>UniRef50_Q41399 Cluster: Chalcone reductase; n=4;
eudicotyledons|Rep: Chalcone reductase - Sesbania
rostrata
Length = 322
Score = 117 bits (282), Expect = 2e-25
Identities = 62/164 (37%), Positives = 96/164 (58%), Gaps = 10/164 (6%)
Frame = +2
Query: 56 EVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYET 235
++P + +N+G MP IG GT + + V L + + AI VG RHFD+ASVY T
Sbjct: 5 KIPEVLLNSGHKMPVIGMGTSVESRPSNDV------LASIFVDAIQVGYRHFDSASVYGT 58
Query: 236 ETRNWRTVKMKVEEGVVK-REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 412
E V +E+G++K R+++FIT+K WNT + A+ +LKKLG++Y+DLYL+
Sbjct: 59 EEAIGMAVSKAIEQGLIKSRDEVFITSKPWNTDAHHDLIVPALKTTLKKLGMEYVDLYLI 118
Query: 413 HWPIGLNAD------YSHSDV---DFMETWRGLEDAQRMGILKA 517
HWP+ L D +S D+ D TW+ +E+ R+G+ K+
Sbjct: 119 HWPVRLRHDLENPVIFSKEDLLPFDIEGTWKAMEECYRLGLAKS 162
>UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA -
Drosophila melanogaster (Fruit fly)
Length = 322
Score = 115 bits (277), Expect = 1e-24
Identities = 58/168 (34%), Positives = 96/168 (57%), Gaps = 13/168 (7%)
Frame = +2
Query: 53 MEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYE 232
M P+ ++NG++MP +G GT+ +S + + V AID+G RHFD A +Y
Sbjct: 1 MSTPNFLLSNGKNMPMLGLGTW---------RSPPEVVTQAVKDAIDIGYRHFDCAHIYG 51
Query: 233 TETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 412
E + ++ K++EGVV R+++FIT+KLWNT H+ V A S++ LG+ Y++LYLM
Sbjct: 52 NEAQVGAALREKMDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLM 111
Query: 413 HWPIGLNADYSH-------------SDVDFMETWRGLEDAQRMGILKA 517
HWP+ + + D+D+++TWR +E+ G+ +A
Sbjct: 112 HWPMAYKSGSDNLYPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQA 159
Score = 41.1 bits (92), Expect = 0.025
Identities = 17/35 (48%), Positives = 24/35 (68%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G + IG+SNFN+QQ+ R+L +KP +QIE H
Sbjct: 155 GLCQAIGVSNFNEQQMNRLLSVAKLKPVVLQIECH 189
>UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9;
Endopterygota|Rep: ENSANGP00000031808 - Anopheles
gambiae str. PEST
Length = 316
Score = 113 bits (271), Expect = 5e-24
Identities = 64/164 (39%), Positives = 88/164 (53%), Gaps = 12/164 (7%)
Frame = +2
Query: 59 VPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETE 238
VP+ NG +P G GT+ S Q+ V AIDVG RH D A VY+ E
Sbjct: 6 VPNAIFKNGNSIPMFGLGTW---------NSPPGQVAQAVKDAIDVGYRHIDCAHVYQNE 56
Query: 239 TRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 418
+ K+ EGVVKRED+F+T+KLWNT HR V A +L+ L LDY+DLYL+HW
Sbjct: 57 HEVGEGIAAKIAEGVVKREDLFVTSKLWNTFHRPDLVEGACKTTLQNLKLDYLDLYLIHW 116
Query: 419 PIG---------LNAD---YSHSDVDFMETWRGLEDAQRMGILK 514
P+G + D + SD D+++TW +E G+++
Sbjct: 117 PVGYQEGTELFPMGPDGKTFLFSDADYVDTWPEMEKLVDAGLVR 160
Score = 40.3 bits (90), Expect = 0.044
Identities = 20/50 (40%), Positives = 28/50 (56%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSKTFRKKWWNFVSLK 651
G ++ IG+SNFN +Q++RVL I P QIE H + K F + K
Sbjct: 157 GLVRNIGVSNFNAKQVQRVLDVARIPPATNQIECHPYLHQSKITTFCAEK 206
>UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep:
GCY protein - Lodderomyces elongisporus (Yeast)
(Saccharomyces elongisporus)
Length = 295
Score = 112 bits (269), Expect = 9e-24
Identities = 58/146 (39%), Positives = 91/146 (62%), Gaps = 2/146 (1%)
Frame = +2
Query: 74 MNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWR 253
+NNG +PAIG GT+L +++ K+ + A+ G +H DTA+ Y E + R
Sbjct: 14 LNNGLKIPAIGLGTWLADEEDAAYKA--------TLTALKNGYKHIDTAAAYGNEDQVGR 65
Query: 254 TVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 433
+ + GV R++IF+TTKLWN QH+ E A+++SLKKLGL+Y+DLYL+HWP+ ++
Sbjct: 66 AI---ADSGV-SRDEIFVTTKLWNDQHKDPE--GALDESLKKLGLEYVDLYLIHWPLSVD 119
Query: 434 --ADYSHSDVDFMETWRGLEDAQRMG 505
+ + D DF++TWR L+ + G
Sbjct: 120 PKTEKPYDDYDFVDTWRNLQKIYKEG 145
Score = 33.5 bits (73), Expect = 5.0
Identities = 17/35 (48%), Positives = 25/35 (71%), Gaps = 2/35 (5%)
Frame = +1
Query: 508 IKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVH 606
+K IG+SNFNK++L+++L EG + P QIE H
Sbjct: 148 VKAIGVSNFNKKKLDKLLNSEGVNVVPVINQIEAH 182
>UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 333
Score = 111 bits (268), Expect = 1e-23
Identities = 61/164 (37%), Positives = 89/164 (54%), Gaps = 13/164 (7%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
S+ + +G MP +G GT+ K K ++ + A+D G RHFD A +Y E
Sbjct: 4 SVTLPSGHAMPLVGLGTW---------KLKADEVAGAIGAAVDAGYRHFDCALIYGNEKE 54
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
++ ++ +KRED+FITTK+WNT H + +VA+ N SL L LDYIDLY+MHWP+
Sbjct: 55 VGVALREAMQRLGLKREDVFITTKVWNTFHAKEDVAECFNRSLTDLQLDYIDLYIMHWPL 114
Query: 425 GL-------------NADYSHSDVDFMETWRGLEDAQRMGILKA 517
G D +SDV ++ETW +ED + G K+
Sbjct: 115 GFQNLGPTVMFPRTETGDIVYSDVHYLETWSAMEDLVKTGKCKS 158
Score = 44.4 bits (100), Expect = 0.003
Identities = 20/46 (43%), Positives = 29/46 (63%)
Frame = +1
Query: 469 DLARIGRCSANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
DL + G+C K +GLSNFN +QL+ VL+ T+ P +Q+E H
Sbjct: 149 DLVKTGKC------KSLGLSNFNSKQLDDVLQHSTVPPSVLQVESH 188
>UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep:
Aldose reductase - Mus musculus (Mouse)
Length = 316
Score = 111 bits (267), Expect = 2e-23
Identities = 64/160 (40%), Positives = 89/160 (55%), Gaps = 11/160 (6%)
Frame = +2
Query: 68 LKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRN 247
L++NNG MP +G GT+ KS Q+ + V AID+G RH D A VY+ E
Sbjct: 5 LELNNGTKMPTLGLGTW---------KSPPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEV 55
Query: 248 WRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 427
++ K++E VVKR+D+FI +KLW T H ++ V A +L L LDY+DLYL+HWP G
Sbjct: 56 GVALQEKLKEQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTG 115
Query: 428 L--NADY---------SHSDVDFMETWRGLEDAQRMGILK 514
DY SD DF++TW +E G++K
Sbjct: 116 FKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVK 155
Score = 36.3 bits (80), Expect = 0.71
Identities = 21/44 (47%), Positives = 27/44 (61%), Gaps = 2/44 (4%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHSKTFRKK 627
G +K IG+SNFN Q+ER+L K G KP QIE H ++K
Sbjct: 152 GLVKTIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEK 195
>UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 316
Score = 111 bits (266), Expect = 2e-23
Identities = 61/160 (38%), Positives = 89/160 (55%), Gaps = 11/160 (6%)
Frame = +2
Query: 59 VPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETE 238
V SLK+N+G +PAIG GT+ +SK ++ + A+ G RH D A VY+ +
Sbjct: 2 VQSLKLNSGYSIPAIGLGTW---------QSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQ 52
Query: 239 TRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 418
+K ++EG VKRE++FIT+K+WNT H + + I+ L L L Y+DL L+HW
Sbjct: 53 KEVGEALKEILDEGKVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHW 112
Query: 419 -----------PIGLNADYSHSDVDFMETWRGLEDAQRMG 505
P G N +SDVD++ETW+ E AQ+ G
Sbjct: 113 PQGYAEGAELFPAGENGKMRYSDVDYLETWKAFEAAQKAG 152
Score = 37.9 bits (84), Expect = 0.23
Identities = 15/35 (42%), Positives = 22/35 (62%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G + IGLSNF Q++RV +KP +Q+E+H
Sbjct: 152 GKCRSIGLSNFTHSQIQRVWDAAEVKPACLQVELH 186
>UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18;
n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member
C18 - Mus musculus (Mouse)
Length = 323
Score = 110 bits (265), Expect = 3e-23
Identities = 57/165 (34%), Positives = 93/165 (56%), Gaps = 11/165 (6%)
Frame = +2
Query: 56 EVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYET 235
++ +++N+G +P +G GTY + +K K + + AIDVG H D + +Y+
Sbjct: 4 KIQKIELNDGHSIPVLGFGTYATEEH---LKKKSMESTKI---AIDVGFCHIDCSHLYQN 57
Query: 236 ETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 415
E + + K+E+G VKREDIF T+KLW+T HR V ++ +SL+KL LDY+DLYL+H
Sbjct: 58 EEEIGQAILSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIH 117
Query: 416 WPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGILKA 517
+P+ L + + VD +TW +E + G+ K+
Sbjct: 118 FPVSLKPGNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKS 162
Score = 37.9 bits (84), Expect = 0.23
Identities = 20/42 (47%), Positives = 26/42 (61%), Gaps = 2/42 (4%)
Frame = +1
Query: 487 RCSANGYIKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVH 606
+C G K IG+SNFN++QLE +L K G KP Q+E H
Sbjct: 153 KCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECH 194
>UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep:
Aldose reductase - Homo sapiens (Human)
Length = 316
Score = 108 bits (259), Expect = 1e-22
Identities = 62/161 (38%), Positives = 87/161 (54%), Gaps = 11/161 (6%)
Frame = +2
Query: 68 LKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRN 247
L +NNG MP +G GT+ KS Q+ + V AIDVG RH D A VY+ E
Sbjct: 5 LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 248 WRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 427
++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+DLYL+HWP G
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 428 L-----------NADYSHSDVDFMETWRGLEDAQRMGILKA 517
+ + SD + ++TW +E+ G++KA
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
Score = 34.7 bits (76), Expect = 2.2
Identities = 20/44 (45%), Positives = 26/44 (59%), Gaps = 2/44 (4%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHSKTFRKK 627
G +K IG+SNFN Q+E +L K G KP QIE H ++K
Sbjct: 152 GLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEK 195
>UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5;
Bacteroidetes|Rep: Aldehyde reductase - Croceibacter
atlanticus HTCC2559
Length = 316
Score = 106 bits (255), Expect = 4e-22
Identities = 57/161 (35%), Positives = 88/161 (54%), Gaps = 11/161 (6%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
+LK +G +P+IG GT+ KS + ++ V A++ G +H D A+ Y+ E
Sbjct: 3 TLKFRDGDSIPSIGLGTW---------KSDPEDVKKAVKIALENGYKHIDCAAAYDNEDA 53
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
K E G VKREDIF+T+KLWN H++ +V A+ +LK L LDY+DLYLMHWP+
Sbjct: 54 VGEAFKESFESGNVKREDIFVTSKLWNNAHKKEDVIPALKKTLKDLNLDYLDLYLMHWPV 113
Query: 425 GLNAD---YSHSDVDFM--------ETWRGLEDAQRMGILK 514
+ D D++ ET + +A++ G++K
Sbjct: 114 AFKPSVNGFPEKDEDYLSLEEAPLHETLNAMIEAKKQGLIK 154
Score = 35.5 bits (78), Expect = 1.2
Identities = 17/49 (34%), Positives = 28/49 (57%)
Frame = +1
Query: 460 LHGDLARIGRCSANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
LH L + G IK +G+SNF+K++LE + + P+ Q+E+H
Sbjct: 137 LHETLNAMIEAKKQGLIKHVGVSNFSKEKLESLKGKVEEMPEMNQVELH 185
>UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like
protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase
family 1 member C-like protein 2 - Homo sapiens (Human)
Length = 320
Score = 98.3 bits (234), Expect(2) = 5e-22
Identities = 48/113 (42%), Positives = 69/113 (61%)
Frame = +2
Query: 89 DMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMK 268
D+PA+G ++ K+ ++ + V AID G RHFD A Y E ++ K
Sbjct: 3 DIPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCK 53
Query: 269 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 427
++EG V+RED+FI TKLW T H+++ V A SLK L L+Y+DLYL+HWP+G
Sbjct: 54 IKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
Score = 38.7 bits (86), Expect = 0.13
Identities = 23/48 (47%), Positives = 29/48 (60%), Gaps = 2/48 (4%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHSKTFRKKWWNF 639
G +K IG+SNFN +QLER+L K G KP QIE H +K +F
Sbjct: 162 GLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISF 209
Score = 29.1 bits (62), Expect(2) = 5e-22
Identities = 10/22 (45%), Positives = 15/22 (68%)
Frame = +2
Query: 449 SDVDFMETWRGLEDAQRMGILK 514
SD DF++TW +ED G++K
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVK 165
>UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4;
Catarrhini|Rep: Isoform 2 of Q96JD6 - Homo sapiens
(Human)
Length = 263
Score = 98.3 bits (234), Expect(2) = 5e-22
Identities = 48/113 (42%), Positives = 69/113 (61%)
Frame = +2
Query: 89 DMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMK 268
D+PA+G ++ K+ ++ + V AID G RHFD A Y E ++ K
Sbjct: 3 DIPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCK 53
Query: 269 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 427
++EG V+RED+FI TKLW T H+++ V A SLK L L+Y+DLYL+HWP+G
Sbjct: 54 IKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
Score = 33.1 bits (72), Expect = 6.6
Identities = 13/22 (59%), Positives = 18/22 (81%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKE 567
G +K IG+SNFN +QLER+L +
Sbjct: 162 GLVKNIGVSNFNHEQLERLLNK 183
Score = 29.1 bits (62), Expect(2) = 5e-22
Identities = 10/22 (45%), Positives = 15/22 (68%)
Frame = +2
Query: 449 SDVDFMETWRGLEDAQRMGILK 514
SD DF++TW +ED G++K
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVK 165
>UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13;
Pezizomycotina|Rep: Aldehyde reductase - Coccidioides
posadasii
Length = 314
Score = 105 bits (253), Expect = 8e-22
Identities = 59/162 (36%), Positives = 90/162 (55%), Gaps = 11/162 (6%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
+ ++N G D+PAIG GT+ D+N D V+ A+ G RH DTA+VY TE
Sbjct: 7 TFRLNTGEDIPAIGFGTWQ--DENAQ--------EDAVLTALSAGYRHIDTAAVYGTE-- 54
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
+ + + + R+++FIT+KLWN +HR +V QAI+ SLK L +DY+DLYLMHWP
Sbjct: 55 --KAIGRALARSRLSRDELFITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMHWPA 112
Query: 425 GL-----------NADYSHSDVDFMETWRGLEDAQRMGILKA 517
+ D+D+++T++ +E + G KA
Sbjct: 113 AFAPGDDMFPKDSQGNSKTVDIDYVDTYKAMEKLVKSGKTKA 154
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/36 (44%), Positives = 27/36 (75%)
Frame = +1
Query: 499 NGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
+G K IG+SNF+K ++ER+L+ +I P +Q+E+H
Sbjct: 149 SGKTKAIGISNFSKGEMERLLESCSIVPAVMQMELH 184
>UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28;
Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza
sativa (Rice)
Length = 323
Score = 103 bits (247), Expect = 4e-21
Identities = 61/167 (36%), Positives = 91/167 (54%), Gaps = 9/167 (5%)
Frame = +2
Query: 44 ASTMEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTAS 223
A+ EV +L+ GR MPA+G GT + S + + R + A++VG RHFDTA+
Sbjct: 2 AAVPEV-ALRHGAGRPMPAVGVGT-----ADSAATSPETK-RGAALAALEVGFRHFDTAA 54
Query: 224 VYETETRNWRTVKMKVEEGVV-KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYID 400
+Y TE + G+V RE++F+TTKLW TQ V ++ +SL+ L ++Y+D
Sbjct: 55 LYGTEAPLGEAIAEATRRGLVASREEVFVTTKLWCTQCHPGLVLPSLRESLRNLQMEYVD 114
Query: 401 LYLMHWPIGLN-----ADYSHSDV---DFMETWRGLEDAQRMGILKA 517
LYL+HWPI + D DF WR +E+ R+G+ KA
Sbjct: 115 LYLVHWPISVKPGPPMLPVKREDAVPFDFEGVWRAMEECHRLGLAKA 161
Score = 34.3 bits (75), Expect = 2.9
Identities = 15/39 (38%), Positives = 23/39 (58%)
Frame = +1
Query: 490 CSANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
C G K IG+SNF + L+++L TI P Q+E++
Sbjct: 153 CHRLGLAKAIGVSNFTTKHLDKLLAVATIPPAVNQVEMN 191
>UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase;
n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid
dehydrogenase - Xenopus tropicalis (Western clawed frog)
(Silurana tropicalis)
Length = 324
Score = 103 bits (246), Expect = 5e-21
Identities = 56/161 (34%), Positives = 84/161 (52%), Gaps = 11/161 (6%)
Frame = +2
Query: 68 LKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRN 247
+++N+G MP IG GTY K + AIDVG RH D A +Y E
Sbjct: 9 VELNDGHKMPVIGFGTY------APPKFPKSLAEEGTKVAIDVGYRHIDCAFLYGNEEEV 62
Query: 248 WRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 427
R ++ K+ +G VKRED+F T KLW+T H V A+ SLK L LDY+DL+++H P+
Sbjct: 63 GRAIRAKIADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPME 122
Query: 428 L-----------NADYSHSDVDFMETWRGLEDAQRMGILKA 517
N + + + D +TW+ LE + G++++
Sbjct: 123 FKPGDDLFPADENGKFIYHNTDLRDTWKALEKCKDAGLVRS 163
Score = 36.7 bits (81), Expect = 0.54
Identities = 23/67 (34%), Positives = 35/67 (52%), Gaps = 4/67 (5%)
Frame = +1
Query: 487 RCSANGYIKGIGLSNFNKQQLERVLKEGTI--KPDAIQIEVHSKTFRKKWWNFVSLK--V 654
+C G ++ IG+SNFN +QLE +L + KP Q+E H + K F K V
Sbjct: 154 KCKDAGLVRSIGVSNFNHKQLELILNMPGLKYKPVCNQVECHVYLNQSKLLEFCKSKDIV 213
Query: 655 L*SWAIL 675
L +++L
Sbjct: 214 LVGYSVL 220
>UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2;
Corynebacterium|Rep: Putative oxidoreductase -
Corynebacterium diphtheriae
Length = 290
Score = 102 bits (245), Expect = 7e-21
Identities = 50/121 (41%), Positives = 73/121 (60%)
Frame = +2
Query: 59 VPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETE 238
+P++ +N+G +MPAIG GTY K +++ V AI+VG RH DTAS+Y+ E
Sbjct: 11 IPTITLNDGTEMPAIGFGTY---------KLREQDAYRAVRSAIEVGYRHIDTASLYKNE 61
Query: 239 TRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 418
R V + G V R+++FITTK+WN H ++ +SL +LGLDYID ++HW
Sbjct: 62 EEVGRAVADAITAGEVARDELFITTKVWNDMHGDQLTQRSFQESLHRLGLDYIDCCMVHW 121
Query: 419 P 421
P
Sbjct: 122 P 122
>UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 288
Score = 102 bits (245), Expect = 7e-21
Identities = 57/164 (34%), Positives = 95/164 (57%), Gaps = 11/164 (6%)
Frame = +2
Query: 59 VPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETE 238
+P +++G+ MP +G GT F S ++DVV+RAI+ G RHFDTA+VY+TE
Sbjct: 1 MPEAALSSGKPMPRVGMGT-ASFPLGATDPST---VKDVVLRAIEAGYRHFDTAAVYQTE 56
Query: 239 TRNWRTVKMKVEEGVV-KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 415
V V G+V R++++IT+KLW V ++ +L+K+ ++Y+DLYL+H
Sbjct: 57 AILGDAVAEAVRAGLVASRDELYITSKLWVAHAHPGHVLPSLRRALRKMQMEYLDLYLIH 116
Query: 416 WPIGL-------NADYSHSDVDFME---TWRGLEDAQRMGILKA 517
+P+ + + YS D+ M+ W+ +E+ QR+G+ KA
Sbjct: 117 FPVSMRLAEDPESMTYSKDDLVMMDMEGVWKEMEECQRLGLTKA 160
Score = 41.5 bits (93), Expect = 0.019
Identities = 23/64 (35%), Positives = 32/64 (50%)
Frame = +1
Query: 460 LHGDLARIGRCSANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSKTFRKKWWNF 639
+ G + C G K IG+SNF+ ++LE +L TI P A Q+EVH + K F
Sbjct: 142 MEGVWKEMEECQRLGLTKAIGVSNFSCKKLETLLSFATISPAANQVEVHPYCRQNKLREF 201
Query: 640 VSLK 651
K
Sbjct: 202 CKEK 205
>UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 320
Score = 102 bits (245), Expect = 7e-21
Identities = 60/155 (38%), Positives = 86/155 (55%), Gaps = 1/155 (0%)
Frame = +2
Query: 56 EVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYET 235
+VP ++NG MP+IG GT+ + G + V+ A+ G RH DTA++Y+
Sbjct: 4 KVPIFTLSNGVLMPSIGLGTWQMTGEEG---------KTVIRNAVLAGYRHIDTATLYQN 54
Query: 236 ETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 415
E + + EG++KREDIFITTK + + V +A+ +SLK+L LDY+DLYL H
Sbjct: 55 EHQIGDALAELFAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAH 114
Query: 416 WPIGLNADYS-HSDVDFMETWRGLEDAQRMGILKA 517
P D S SDV + WRG E +G+ KA
Sbjct: 115 IPASTKDDGSFRSDVKVEDIWRGFEKVYGLGLTKA 149
Score = 33.5 bits (73), Expect = 5.0
Identities = 14/35 (40%), Positives = 22/35 (62%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G K IG+SNFN+ Q+ R++ + A Q+E+H
Sbjct: 145 GLTKAIGVSNFNESQIVRIMNIQKVPIHASQLELH 179
>UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep:
Protein GCY - Saccharomyces cerevisiae (Baker's yeast)
Length = 312
Score = 102 bits (245), Expect = 7e-21
Identities = 55/125 (44%), Positives = 75/125 (60%)
Frame = +2
Query: 68 LKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRN 247
L +N G +P IG GT+ +SK+ V+ A+ G RH DTA++Y E +
Sbjct: 12 LSLNTGAQIPQIGLGTW---------QSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQ- 61
Query: 248 WRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 427
V +++ V RE+IF+TTKLW TQH EVA ++ SLK+LGLDY+DLYLMHWP
Sbjct: 62 ---VGQAIKDSGVPREEIFVTTKLWCTQHHEPEVA--LDQSLKRLGLDYVDLYLMHWPAR 116
Query: 428 LNADY 442
L+ Y
Sbjct: 117 LDPAY 121
>UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30;
Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus
(Mouse)
Length = 316
Score = 102 bits (244), Expect = 1e-20
Identities = 56/156 (35%), Positives = 84/156 (53%), Gaps = 11/156 (7%)
Frame = +2
Query: 83 GRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVK 262
G MP +G GT+ KS ++R+ V AID G RH D A VY+ E+ ++
Sbjct: 10 GAKMPIVGLGTW---------KSPPAKVREAVKVAIDAGYRHIDCAYVYQNESEVGEAIQ 60
Query: 263 MKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA-- 436
K++E VKRED+FI +KLW+T ++ V +A ++L L LDY+DLYL+HWP G +
Sbjct: 61 EKIQEKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGFQSGN 120
Query: 437 ---------DYSHSDVDFMETWRGLEDAQRMGILKA 517
S F++ W +E+ G++KA
Sbjct: 121 VFLPTDDKGSILSSKYTFLDAWEAMEELVDQGLVKA 156
Score = 34.3 bits (75), Expect = 2.9
Identities = 17/44 (38%), Positives = 27/44 (61%), Gaps = 2/44 (4%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTI--KPDAIQIEVHSKTFRKK 627
G +K +G+SNFN Q+ER+L + + KP Q+E H ++K
Sbjct: 152 GLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEK 195
>UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium
discoideum|Rep: Aldehyde reductase - Dictyostelium
discoideum AX4
Length = 297
Score = 101 bits (243), Expect = 1e-20
Identities = 59/163 (36%), Positives = 86/163 (52%), Gaps = 11/163 (6%)
Frame = +2
Query: 62 PSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETET 241
PS K+++G +P +G GT+ K++ + V A+D G RH D A+VY E
Sbjct: 3 PSFKLSSGHKIPLVGFGTW---------KAETTLVGKAVEVALDAGYRHIDCAAVYLNEK 53
Query: 242 RNWRTVKMK-VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 418
K E VKRED+FIT+KLWNT H++ V A+ +L LGL Y+DLYL+HW
Sbjct: 54 EVGEAFTKKFTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVHW 113
Query: 419 PIGLNADYSHSD----------VDFMETWRGLEDAQRMGILKA 517
P+ +Y+ +D V ETW +E G++K+
Sbjct: 114 PVAF--EYTSNDIQTSGSTQEFVSIRETWEEMEKLVDAGLVKS 154
Score = 41.9 bits (94), Expect = 0.014
Identities = 20/35 (57%), Positives = 23/35 (65%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G +K IGLSNFN Q L VL IKP A Q+E+H
Sbjct: 150 GLVKSIGLSNFNVQGLMEVLSYARIKPAANQVELH 184
>UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate
division TM7 genomosp. GTL1|Rep: Aldehyde reductase -
candidate division TM7 genomosp. GTL1
Length = 299
Score = 101 bits (241), Expect = 2e-20
Identities = 55/161 (34%), Positives = 85/161 (52%), Gaps = 11/161 (6%)
Frame = +2
Query: 68 LKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRN 247
L + N + +P +G GT+ + D+V AI G RH D A +Y E
Sbjct: 4 LTLRNKQTLPLLGYGTW---------ELPTGTTADLVETAIKAGYRHIDCAMIYGNEKEV 54
Query: 248 WRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI- 424
++ +++GVVKRED+F+T+KLWNT H + +V A +L LGLDY+DLYL+HW +
Sbjct: 55 GEGIRRTIDQGVVKREDLFVTSKLWNTDHAQVDVGVACRKTLNDLGLDYLDLYLIHWGVA 114
Query: 425 ---GLNADYSHSD-------VDFMETWRGLEDAQRMGILKA 517
G N + D + ETW+ +E+ G++K+
Sbjct: 115 FEHGDNLEPLDDDGVAKFSFISMKETWQAMEELVEQGLVKS 155
>UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=3; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 324
Score = 101 bits (241), Expect = 2e-20
Identities = 52/125 (41%), Positives = 79/125 (63%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
S K+N+G +PA+G GT + D + +VV AI G RH DTA +Y +E
Sbjct: 6 SFKLNDGHSIPALGLGT-----------ASDGNVEEVVYAAIKNGYRHIDTAFIYGSEVD 54
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
+ +K ++E +VKRE++F+TTK+W T + R V+++++ SLK L LDY+DL L+HWP+
Sbjct: 55 VGKGIKRAIDEELVKRENLFVTTKVWPTFYNR--VSESLDISLKDLSLDYVDLLLVHWPV 112
Query: 425 GLNAD 439
L AD
Sbjct: 113 SLLAD 117
>UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5;
Saccharomycetales|Rep: D-arabinose dehydrogenase -
Pichia stipitis (Yeast)
Length = 326
Score = 101 bits (241), Expect = 2e-20
Identities = 52/122 (42%), Positives = 76/122 (62%)
Frame = +2
Query: 74 MNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWR 253
++NG+ +PA+G GT V +L++ V+ A+ G RH DTA Y TE +
Sbjct: 12 LSNGKTIPALGLGT--------VPPEDPHELKEQVITAVKAGYRHIDTAWYYGTEEYIGQ 63
Query: 254 TVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 433
+K EEG+VKRED+FITTK+W + R E ++++ SL LGLDY+DL+L HWP+ L+
Sbjct: 64 ALKQLFEEGIVKREDLFITTKVWPSFWRNPE--KSLDKSLADLGLDYVDLFLQHWPVVLH 121
Query: 434 AD 439
D
Sbjct: 122 GD 123
>UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1
protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo
sapiens "AKR1B1 protein. - Takifugu rubripes
Length = 330
Score = 100 bits (240), Expect = 3e-20
Identities = 54/123 (43%), Positives = 72/123 (58%)
Frame = +2
Query: 59 VPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETE 238
+PS+ +N G MP +G GT+ KS + V AI G RH DTA VYE E
Sbjct: 2 IPSVTLNTGALMPVLGLGTW---------KSGKGVTTEAVKVAIGAGYRHIDTAYVYENE 52
Query: 239 TRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 418
T V+ +++GVVKRE++FI +KLW T H + V A +L L LDY+DLYLMH+
Sbjct: 53 TEVGAGVQAMIDQGVVKREELFIVSKLWCTFHTPSLVRGACEKTLSSLNLDYVDLYLMHF 112
Query: 419 PIG 427
P+G
Sbjct: 113 PMG 115
Score = 38.3 bits (85), Expect = 0.18
Identities = 21/49 (42%), Positives = 29/49 (59%), Gaps = 2/49 (4%)
Frame = +1
Query: 499 NGYIKGIGLSNFNKQQLERVLKEGTI--KPDAIQIEVHSKTFRKKWWNF 639
+G K IG+SNFNK Q+E VL + + KP QIE H ++K +F
Sbjct: 175 DGLAKAIGISNFNKDQIEAVLNKPGLKHKPATNQIECHPHLNQEKLIHF 223
>UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:
Aldehyde reductase - Salinibacter ruber (strain DSM
13855)
Length = 321
Score = 100 bits (240), Expect = 3e-20
Identities = 53/160 (33%), Positives = 86/160 (53%), Gaps = 10/160 (6%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
S+ NG +MP IG GT+ KS ++ + V A++ G RH D A +Y+ ET
Sbjct: 3 SISFENGDEMPMIGLGTW---------KSPPGEVYEAVTTALEAGYRHVDCAPIYKNETE 53
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
+ + G ++R+D+++T+KLWN H +V A+ +L L LD +DLYL+HWP+
Sbjct: 54 VGAALSDSFDAGGIRRDDVWVTSKLWNNAHHPDDVRPALEQTLSDLRLDALDLYLIHWPV 113
Query: 425 GL--NADYSHSDVDFM--------ETWRGLEDAQRMGILK 514
L D+ S DF+ ETW +E ++ G+++
Sbjct: 114 ALQPEVDFPESPDDFVSPEAVPLTETWAAMEALKKDGLVR 153
Score = 36.7 bits (81), Expect = 0.54
Identities = 13/36 (36%), Positives = 25/36 (69%)
Frame = +1
Query: 499 NGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
+G ++ IG+SNF+ L+ +L G ++P+ Q+E+H
Sbjct: 149 DGLVRHIGVSNFSVPNLQMILDAGEVRPEMNQVEMH 184
>UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1;
Arabidopsis thaliana|Rep: Uncharacterized protein
At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress)
Length = 283
Score = 100 bits (240), Expect = 3e-20
Identities = 58/156 (37%), Positives = 84/156 (53%), Gaps = 7/156 (4%)
Frame = +2
Query: 71 KMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNW 250
K+N G P++G GT+ G+V D V A+ +G RH D A +Y E
Sbjct: 9 KLNTGAKFPSVGLGTWQA--SPGLVG-------DAVAAAVKIGYRHIDCAQIYGNEKEIG 59
Query: 251 RTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP--- 421
+K E+ VVKRED+FIT+KLW T H +V +A+N +LK L L+Y+DLYL+HWP
Sbjct: 60 AVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARI 119
Query: 422 ----IGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
+G+ + + VD TW+ +E G +A
Sbjct: 120 KKGSVGIKPE-NLLPVDIPSTWKAMEALYDSGKARA 154
>UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32;
Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 315
Score = 100 bits (240), Expect = 3e-20
Identities = 58/156 (37%), Positives = 84/156 (53%), Gaps = 7/156 (4%)
Frame = +2
Query: 71 KMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNW 250
K+N G P++G GT+ G+V D V A+ +G RH D A +Y E
Sbjct: 9 KLNTGAKFPSVGLGTWQA--SPGLVG-------DAVAAAVKIGYRHIDCAQIYGNEKEIG 59
Query: 251 RTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP--- 421
+K E+ VVKRED+FIT+KLW T H +V +A+N +LK L L+Y+DLYL+HWP
Sbjct: 60 AVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARI 119
Query: 422 ----IGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
+G+ + + VD TW+ +E G +A
Sbjct: 120 KKGSVGIKPE-NLLPVDIPSTWKAMEALYDSGKARA 154
>UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Opitutaceae bacterium TAV2
Length = 347
Score = 99 bits (238), Expect = 5e-20
Identities = 59/166 (35%), Positives = 88/166 (53%), Gaps = 13/166 (7%)
Frame = +2
Query: 56 EVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYET 235
++P + +G MPAIG GT+ G D + ++ V A ++G RHFD A+VY
Sbjct: 15 KIPQRTLASGARMPAIGMGTF-GSDH-----AAPGEVAASVYAAAELGYRHFDCAAVYSN 68
Query: 236 ETRNWRTVKMKVEEGV-VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 412
E T + + ++RED++IT+KLWN +H +V A SL+ LGLDY+DLYL+
Sbjct: 69 EREIGATFRRILTSNTGIRREDLWITSKLWNDKHAEADVIPAFEKSLRDLGLDYLDLYLI 128
Query: 413 HWPI------GLNADYSHSD------VDFMETWRGLEDAQRMGILK 514
HWP G + D +FM+TWR LE G+++
Sbjct: 129 HWPFPNFHPPGCDVSSRSPDARPYIHAEFMKTWRQLETLHDRGLVR 174
>UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 345
Score = 99 bits (238), Expect = 5e-20
Identities = 55/142 (38%), Positives = 80/142 (56%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
+ K+N G DMPA+G GT+ +SK ++RD V+ A+ G RH D A+VY E
Sbjct: 6 TFKLNTGYDMPAVGLGTW---------QSKKDEVRDAVIAALKCGYRHIDAAAVYGNEQE 56
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
+++ V RE+IF+T+KLWNT H V +A++ SL L DY+DLYL+HWP+
Sbjct: 57 VGDGMRLSG----VPREEIFLTSKLWNTHHHPENVEEAVDKSLADLQTDYLDLYLIHWPV 112
Query: 425 GLNADYSHSDVDFMETWRGLED 490
YS + + + GL D
Sbjct: 113 AFR--YSTTTIQPVNEQTGLID 132
Score = 37.5 bits (83), Expect = 0.31
Identities = 15/35 (42%), Positives = 23/35 (65%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G ++ IG+SNF ++++E +LK I P QIE H
Sbjct: 152 GKVRSIGVSNFTREKIEELLKTAKITPAVNQIEAH 186
>UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose
reductase; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to aldose reductase -
Strongylocentrotus purpuratus
Length = 274
Score = 99.5 bits (237), Expect = 7e-20
Identities = 49/96 (51%), Positives = 59/96 (61%)
Frame = +2
Query: 149 SKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKVEEGVVKREDIFITTKLWNT 328
SK Q+ V AID G RH D A VY E +K K + VVKREDIFIT+KLWN
Sbjct: 7 SKPGQVEAAVKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLWNN 66
Query: 329 QHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA 436
+H +V QA + +LK L L Y+DLYLMHWP+ A
Sbjct: 67 KHHPDDVEQACDITLKNLQLSYVDLYLMHWPMAYQA 102
Score = 42.3 bits (95), Expect = 0.011
Identities = 18/47 (38%), Positives = 32/47 (68%)
Frame = +1
Query: 499 NGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSKTFRKKWWNF 639
+G K IGLSNF+ + ++RV+++ TI+P +Q+E+H ++K F
Sbjct: 109 SGKCKAIGLSNFSMKMMKRVIEKATIQPANLQVELHPLLTQEKLIEF 155
>UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 286
Score = 99.1 bits (236), Expect = 9e-20
Identities = 57/153 (37%), Positives = 84/153 (54%), Gaps = 3/153 (1%)
Frame = +2
Query: 44 ASTMEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLR-DVVMRAIDVG*RHFDTA 220
A T + +NNG +P +G GT+ ++ D Q+ D V+ A+ G RH DTA
Sbjct: 3 ALTKLTDTYTLNNGTKIPIVGFGTW---------QTPDGQVAYDSVLAALKAGYRHIDTA 53
Query: 221 SVYETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYID 400
+ Y E +V + + V RED+F+TTKLWN H +A++ SL KLGLDY+D
Sbjct: 54 AAYGNE----ESVGKAIADSGVAREDLFVTTKLWNADHGYDAAKKALDTSLAKLGLDYVD 109
Query: 401 LYLMHW--PIGLNADYSHSDVDFMETWRGLEDA 493
LYL+HW P + ++ + D TWR +E+A
Sbjct: 110 LYLIHWPNPAAMRDNWEQLNAD---TWRAMEEA 139
>UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep:
Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea)
Length = 321
Score = 99.1 bits (236), Expect = 9e-20
Identities = 55/163 (33%), Positives = 92/163 (56%), Gaps = 10/163 (6%)
Frame = +2
Query: 59 VPSLKMNNG-RDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYET 235
+P + +++G R MP +G GT + + +R V A+ +G RHFDTA++Y +
Sbjct: 5 IPEVPLSSGGRKMPVLGLGTAADPPVD------PETVRKAVTEALKLGYRHFDTAALYNS 58
Query: 236 ETRNWRTVKMKVEEGVVK-REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 412
E + + EG++K R+++FIT+KLW + R V A+ +LK L L+YID+YL+
Sbjct: 59 EQPLGDAIAEALGEGLIKSRDELFITSKLWCSDAHRENVEPALQKTLKNLKLEYIDMYLI 118
Query: 413 HWPIGL---NADYSHSDVDFME-----TWRGLEDAQRMGILKA 517
HWP+ N +Y DF++ W +E+ Q++G+ KA
Sbjct: 119 HWPVSSKPGNYEYPIKKEDFLQMDYKSVWEAMEECQKLGLTKA 161
Score = 32.7 bits (71), Expect = 8.8
Identities = 15/39 (38%), Positives = 22/39 (56%)
Frame = +1
Query: 490 CSANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
C G K IG+SNF+ ++L VL + P Q+EV+
Sbjct: 153 CQKLGLTKAIGVSNFSCKKLSDVLANAKVPPAVNQVEVN 191
>UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44;
Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo
sapiens (Human)
Length = 325
Score = 99.1 bits (236), Expect = 9e-20
Identities = 59/167 (35%), Positives = 87/167 (52%), Gaps = 12/167 (7%)
Frame = +2
Query: 53 MEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYE 232
M + ++ G+ MP IG GT+ KS+ Q++ V A+ VG RH D A++Y
Sbjct: 1 MAASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYG 51
Query: 233 TETRNWRTVKMKVEEG-VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 409
E +K V G V RE++F+T+KLWNT+H +V A+ +L L L+Y+DLYL
Sbjct: 52 NEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYL 111
Query: 410 MHWPIGL---------NAD--YSHSDVDFMETWRGLEDAQRMGILKA 517
MHWP NAD + + ETW+ LE G+++A
Sbjct: 112 MHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQA 158
Score = 41.5 bits (93), Expect = 0.019
Identities = 14/37 (37%), Positives = 26/37 (70%)
Frame = +1
Query: 496 ANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
A G ++ +GLSNFN +Q++ +L +++P +Q+E H
Sbjct: 152 AKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECH 188
>UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila
melanogaster|Rep: CG40064-PA - Drosophila melanogaster
(Fruit fly)
Length = 361
Score = 98.7 bits (235), Expect = 1e-19
Identities = 49/136 (36%), Positives = 80/136 (58%), Gaps = 12/136 (8%)
Frame = +2
Query: 146 KSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKVEEGVVKREDIFITTKLWN 325
K + Q V AI+ G RHFDTA YE E ++ +++ G + RE+IF+TTKLWN
Sbjct: 40 KLRGYQCSAAVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMGNISRENIFLTTKLWN 99
Query: 326 TQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG-----------LNADYSHS-DVDFME 469
T H +V + L+ LG YIDLYLMH+P+G ++ D + ++D+++
Sbjct: 100 THHDPRDVRRICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMSGDELQTVEIDYLD 159
Query: 470 TWRGLEDAQRMGILKA 517
TWR +E+ ++G++++
Sbjct: 160 TWRAMENLVKLGMVRS 175
Score = 37.9 bits (84), Expect = 0.23
Identities = 14/34 (41%), Positives = 25/34 (73%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEV 603
G ++ IGLSNFN +Q++R+++ + KP Q+E+
Sbjct: 171 GMVRSIGLSNFNMEQIQRIIQCSSSKPVVNQVEI 204
>UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon
cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon
cuniculi
Length = 301
Score = 98.7 bits (235), Expect = 1e-19
Identities = 49/118 (41%), Positives = 71/118 (60%)
Frame = +2
Query: 71 KMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNW 250
K+NNG+++P +G GT+ G + V L + A+ +G RH DTA +Y E
Sbjct: 7 KLNNGKEIPTVGLGTW-GMEDEAV-------LEGAIRNALSLGYRHIDTAFIYGNEKMIG 58
Query: 251 RTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
+K +EGVV+R+D+FIT+KLWNT H E + SL L +DY+DLYL+HWP+
Sbjct: 59 NILKKLFDEGVVQRKDLFITSKLWNTFHGCPE--DGLRRSLNDLQMDYVDLYLIHWPV 114
Score = 39.9 bits (89), Expect = 0.058
Identities = 21/50 (42%), Positives = 28/50 (56%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSKTFRKKWWNFVSLK 651
G K IG+SNF K E++L I P AIQIE+H +K+ F+ K
Sbjct: 152 GLAKSIGISNFGKANTEKILGTCRICPAAIQIELHPYLNQKELVEFMKSK 201
>UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 286
Score = 98.3 bits (234), Expect = 2e-19
Identities = 55/155 (35%), Positives = 85/155 (54%)
Frame = +2
Query: 53 MEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYE 232
M+VP + +NNG +MP +G G + + ++ + V AI VG R DTA+ Y
Sbjct: 1 MQVPKVTLNNGVEMPILGYGVF---------QIPPEKTEECVYEAIKVGYRLIDTAASYM 51
Query: 233 TETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 412
E R +K ++EG+V+RE++F+TTKLW + +A SLKKL L+YIDLYL+
Sbjct: 52 NEEGVGRAIKRAIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLI 111
Query: 413 HWPIGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
H P G D W+ +E+ + G+++A
Sbjct: 112 HQPFG----------DVHCAWKAMEEMYKDGLVRA 136
>UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep:
AkrI - Butyrivibrio fibrisolvens
Length = 172
Score = 98.3 bits (234), Expect = 2e-19
Identities = 53/150 (35%), Positives = 79/150 (52%)
Frame = +2
Query: 68 LKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRN 247
+K+NNG +P G GTY DQN S V A+ G RH DTA+ YE E
Sbjct: 8 IKLNNGTAIPMFGYGTYKIKDQNEAYNS--------VRLALKNGYRHIDTAAFYENEKFV 59
Query: 248 WRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 427
+K +EE KREDIF+T+K W T+ + A ++ ++ +DY+DLYL+HWP
Sbjct: 60 ANAIKDFMEESQTKREDIFVTSKAWKTELGYDKTLAAFEKTMNEMQMDYLDLYLVHWPAS 119
Query: 428 LNADYSHSDVDFMETWRGLEDAQRMGILKA 517
D + + +TW+ + + + G +KA
Sbjct: 120 YAFDDDWENTN-RQTWKAMTEIYKSGRVKA 148
>UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core
eudicotyledons|Rep: Aldose reductase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 316
Score = 97.9 bits (233), Expect = 2e-19
Identities = 54/159 (33%), Positives = 85/159 (53%), Gaps = 10/159 (6%)
Frame = +2
Query: 71 KMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLR-DVVMRAIDVG*RHFDTASVYETETRN 247
++ G +P +G GTY KD++ V +AI +G RHFDTA +Y +E
Sbjct: 7 RLRCGETIPLLGMGTYC--------PQKDRESTISAVHQAIKIGYRHFDTAKIYGSEEAL 58
Query: 248 WRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 427
+ + G V+R+D+F+T+KLW++ H + A+ +LK +GLDY+D YL+HWPI
Sbjct: 59 GTALGQAISYGTVQRDDLFVTSKLWSSDHH--DPISALIQTLKTMGLDYLDNYLVHWPIK 116
Query: 428 L---------NADYSHSDVDFMETWRGLEDAQRMGILKA 517
L D D+ ETW+G+E MG+ ++
Sbjct: 117 LKPGVSEPIPKEDEFEKDLGIEETWQGMERCLEMGLCRS 155
Score = 33.5 bits (73), Expect = 5.0
Identities = 13/40 (32%), Positives = 24/40 (60%)
Frame = +1
Query: 487 RCSANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
RC G + IG+SNF+ +++ +L ++ P Q+E+H
Sbjct: 146 RCLEMGLCRSIGVSNFSSKKIFDLLDFASVSPSVNQVEMH 185
>UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Exiguobacterium sibiricum 255-15
Length = 274
Score = 97.5 bits (232), Expect = 3e-19
Identities = 57/148 (38%), Positives = 80/148 (54%)
Frame = +2
Query: 74 MNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWR 253
+NNG MP +G G + K ++++ + V A+ VG R DTA +YE E R
Sbjct: 6 LNNGLVMPQLGYGVF---------KVPEQEVYEAVREALRVGYRSIDTAMIYENEAGVGR 56
Query: 254 TVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 433
+K + + REDIF+TTK+WN A SL+KLG+DY+DLYL+HWP+
Sbjct: 57 ALK----DSGIPREDIFLTTKVWNKDQGYERTLAAFETSLQKLGVDYVDLYLIHWPM--- 109
Query: 434 ADYSHSDVDFMETWRGLEDAQRMGILKA 517
D+ +M+TWR LE R G KA
Sbjct: 110 ---PDEDL-YMDTWRALEQLYRDGKAKA 133
Score = 41.1 bits (92), Expect = 0.025
Identities = 19/36 (52%), Positives = 25/36 (69%)
Frame = +1
Query: 499 NGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
+G K IG+SNF+ L RVL+EGT+ P QIE+H
Sbjct: 128 DGKAKAIGVSNFHIPHLTRVLEEGTVVPAVNQIELH 163
>UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase
family; n=2; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 305
Score = 97.1 bits (231), Expect = 4e-19
Identities = 54/151 (35%), Positives = 83/151 (54%), Gaps = 3/151 (1%)
Frame = +2
Query: 74 MNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWR 253
+NNG +P +G GT++ NG V V AI G RH D A Y E
Sbjct: 7 LNNGYKIPKLGLGTWMS--ANGEVGK-------AVEIAIKNGYRHIDCAKAYGNEKEVGD 57
Query: 254 TVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 433
+K + +G VKRE++F+TTKLW+T + +V A +SLKKL L+Y+DLY++H P+ +
Sbjct: 58 GIKSAIAKGYVKREELFVTTKLWSTDKHKEDVRPACLESLKKLQLEYLDLYIIHIPLTAD 117
Query: 434 ---ADYSHSDVDFMETWRGLEDAQRMGILKA 517
+++ + ETWR +E G++K+
Sbjct: 118 KKTGEFTEEIIPIEETWREMEKLVEEGLVKS 148
Score = 36.3 bits (80), Expect = 0.71
Identities = 19/46 (41%), Positives = 25/46 (54%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSKTFRKKWWNF 639
G +K IG+SNFN ++LE +L I+P Q E H R K F
Sbjct: 144 GLVKSIGVSNFNIKKLEELLAIAKIQPAVNQFEFHIYYQRPKLHQF 189
>UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1;
Corynebacterium jeikeium K411|Rep: Putative
oxidoreductase - Corynebacterium jeikeium (strain K411)
Length = 285
Score = 97.1 bits (231), Expect = 4e-19
Identities = 51/121 (42%), Positives = 72/121 (59%)
Frame = +2
Query: 59 VPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETE 238
VP+L+MN+G+ P +G G + + D+ V AI+ G RH DTA++Y E
Sbjct: 8 VPTLEMNDGKTTPQLGLGVW---------QLSDEDTYTSVRAAIETGYRHIDTAAIYGNE 58
Query: 239 TRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 418
R V V+ G V+RE++FITTKLWN + +A +S KKLG+DY+DLYL+HW
Sbjct: 59 EAVGRAVADAVKAGDVQREELFITTKLWNADQACGK--EAFAESQKKLGMDYVDLYLLHW 116
Query: 419 P 421
P
Sbjct: 117 P 117
>UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3;
Lactobacillus|Rep: 2,5-didehydrogluconate reductase -
Lactobacillus reuteri 100-23
Length = 288
Score = 97.1 bits (231), Expect = 4e-19
Identities = 51/151 (33%), Positives = 79/151 (52%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
+ +NNG +P +G GT+ ++ V AI+ G RH DTA+VY E
Sbjct: 10 TFNLNNGVKIPCVGYGTF---------RTPADVAEQAVKEAIETGYRHIDTAAVYGNE-- 58
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
V +++ +KRED+F+T+KLWNT + +A ++L +L +DY+DLYL+HWP
Sbjct: 59 --EAVGKGIKDSGIKREDLFVTSKLWNTNRGYEQTKKAFQETLDRLQMDYLDLYLIHWPA 116
Query: 425 GLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
+ ETWR +ED G ++A
Sbjct: 117 NEKQFGDDAAKINAETWRAMEDLYNEGKIRA 147
Score = 32.7 bits (71), Expect = 8.8
Identities = 14/35 (40%), Positives = 20/35 (57%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G I+ IG+SNF + ++K + P QIEVH
Sbjct: 143 GKIRAIGVSNFMPHHIAELMKTAKVAPAVDQIEVH 177
>UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2;
Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus
sp. (strain CC9311)
Length = 336
Score = 97.1 bits (231), Expect = 4e-19
Identities = 55/165 (33%), Positives = 90/165 (54%), Gaps = 10/165 (6%)
Frame = +2
Query: 50 TMEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVY 229
TM+ SL +NG MP +G GT KS+ +Q+ V AI +G RH D AS+Y
Sbjct: 18 TMQYASL--SNGDRMPLLGLGTG---------KSESRQVYKSVREAIKIGYRHIDCASIY 66
Query: 230 ETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 409
E ++ ++ + R +++IT+KLW+ H + V A++ SL+ LG+DY++LYL
Sbjct: 67 GNEEEVGDAIRDAIQNHEITRSELWITSKLWSNCHGKNHVEAALSQSLQNLGVDYLNLYL 126
Query: 410 MHWPIGLNADYSHSD-VD---------FMETWRGLEDAQRMGILK 514
+HWP+G+ + + ++ VD ETW +E + G+ K
Sbjct: 127 IHWPVGIRPEKTFAESVDDLLTPEESPISETWEAMESTRDKGLTK 171
>UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus acidophilus
Length = 285
Score = 96.7 bits (230), Expect = 5e-19
Identities = 55/148 (37%), Positives = 86/148 (58%)
Frame = +2
Query: 74 MNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWR 253
+NNG +P IG GT+ D G V + V+ A++ G RH DTAS Y E
Sbjct: 12 LNNGVKIPIIGFGTWQTPD--GEVAEES------VLAALNCGYRHIDTASAYGNED---- 59
Query: 254 TVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 433
+V +++ + R ++FITTKLWN+ H + +AI+ SL L LDY+D+YL+HWP +
Sbjct: 60 SVGRAIQKSGINRHELFITTKLWNSDHGYEKTKKAIDQSLLDLKLDYLDMYLIHWPNPSS 119
Query: 434 ADYSHSDVDFMETWRGLEDAQRMGILKA 517
++++ E+WR +E+A R G ++A
Sbjct: 120 MRDHWAEIN-AESWRAMEEAVRAGKIRA 146
>UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate
dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent
D-sorbitol-6-phosphate dehydrogenase - Malus domestica
(Apple) (Malus sylvestris)
Length = 310
Score = 96.7 bits (230), Expect = 5e-19
Identities = 54/166 (32%), Positives = 94/166 (56%), Gaps = 15/166 (9%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
++ +++G +MP IG G + + + +L++V++ AI +G RHFD A+ Y++E
Sbjct: 3 TVTLSSGYEMPVIGLGLW---------RLEKDELKEVILNAIKIGYRHFDCAAHYKSEAD 53
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP- 421
+ + G+VKRE++FITTK+WN+ H V +A +SL+KL +DY+DLYL+H+P
Sbjct: 54 VGEALAEAFKTGLVKREELFITTKIWNSDH--GHVVEACKNSLEKLQIDYLDLYLVHYPM 111
Query: 422 ------IGLNADYSHSD--------VDFMETWRGLEDAQRMGILKA 517
IG A D + +TW G+E +G++++
Sbjct: 112 PTKHNAIGKTASLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRS 157
>UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone
synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent
6'-deoxychalcone synthase - Glycine max (Soybean)
Length = 315
Score = 96.7 bits (230), Expect = 5e-19
Identities = 54/169 (31%), Positives = 91/169 (53%), Gaps = 11/169 (6%)
Frame = +2
Query: 44 ASTMEVPSLKMNNG---RDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFD 214
A+ +E+P++ N + MP +G G+ F + K ++ ++ A+ G RHFD
Sbjct: 2 AAAIEIPTIVFPNSSAQQRMPVVGMGSAPDF-------TCKKDTKEAIIEAVKQGYRHFD 54
Query: 215 TASVYETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDY 394
TA+ Y +E +K + G+V R+D+F+T+KLW T++ V A+ SLK L L+Y
Sbjct: 55 TAAAYGSEQALGEALKEAIHLGLVSRQDLFVTSKLWVTENHPHLVLPALRKSLKTLQLEY 114
Query: 395 IDLYLMHWPIG-----LNADYSHSDV---DFMETWRGLEDAQRMGILKA 517
+DLYL+HWP+ + D+ D W +E+ Q++G+ KA
Sbjct: 115 LDLYLIHWPLSSQPGKFSFPIEVEDLLPFDVKGVWESMEECQKLGLTKA 163
Score = 37.1 bits (82), Expect = 0.41
Identities = 18/50 (36%), Positives = 29/50 (58%)
Frame = +1
Query: 490 CSANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSKTFRKKWWNF 639
C G K IG+SNF+ ++L+ +L TI+P Q+E++ +KK F
Sbjct: 155 CQKLGLTKAIGVSNFSVKKLQNLLSVATIRPVVDQVEMNLAWQQKKLREF 204
>UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=2; Tetrahymena thermophila SB210|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 332
Score = 96.3 bits (229), Expect = 6e-19
Identities = 53/152 (34%), Positives = 90/152 (59%), Gaps = 1/152 (0%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
S K+NNG+ MP +G GTYL + SK+ ++ +++ A+D G RH DTA Y+ E
Sbjct: 7 SSKLNNGQIMPLVGLGTYL-------LNSKE-EMTNLLRTALDAGYRHIDTAVNYQNEAM 58
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
++K +EG R+D+FI +K++ ++ + +++ SLK+L LDY+DLY +H+P+
Sbjct: 59 IGESLKTIFKEGKYSRKDLFIVSKVF--PNKGINMLESVKKSLKELQLDYVDLYYLHFPL 116
Query: 425 G-LNADYSHSDVDFMETWRGLEDAQRMGILKA 517
G L+ + W LE+A R+G+ K+
Sbjct: 117 GFLSEKEEFVHLPVHVAWAQLEEAHRLGLAKS 148
Score = 32.7 bits (71), Expect = 8.8
Identities = 17/48 (35%), Positives = 25/48 (52%)
Frame = +1
Query: 460 LHGDLARIGRCSANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEV 603
+H A++ G K IG+SNFN L +L +KP + Q+EV
Sbjct: 130 VHVAWAQLEEAHRLGLAKSIGVSNFNVMALADLLSYAKVKPVSNQVEV 177
>UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 287
Score = 95.9 bits (228), Expect = 8e-19
Identities = 60/151 (39%), Positives = 83/151 (54%), Gaps = 3/151 (1%)
Frame = +2
Query: 74 MNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWR 253
++NG +PA+G GTY D + V S AI G RHFDTAS Y TET
Sbjct: 10 LSNGLSIPAVGFGTYKTGDGDSAVLSN----------AIAQGYRHFDTASFYGTET---- 55
Query: 254 TVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP---I 424
+ V E + RED F+T+KLW T+ +A + +L++LG DY+DLYL+HWP +
Sbjct: 56 ALGQAVAESDIPREDFFLTSKLWKTEMGYDAALRAFDATLERLGTDYLDLYLIHWPRPDL 115
Query: 425 GLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
L D++ D ETWR LE G+++A
Sbjct: 116 ELE-DWAKLD---RETWRALERLYESGLVRA 142
>UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase A - Corynebacterium sp. (strain ATCC 31090)
Length = 278
Score = 95.9 bits (228), Expect = 8e-19
Identities = 54/133 (40%), Positives = 74/133 (55%)
Frame = +2
Query: 53 MEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYE 232
M VPS+ +N+G +P +G G + V D Q V A++VG RH DTA++Y
Sbjct: 1 MTVPSIVLNDGNSIPQLGYGVFK-------VPPADTQR--AVEEALEVGYRHIDTAAIYG 51
Query: 233 TETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 412
E V + + R+D+FITTKLWN +H E A AI +SL KL LD +DLYL+
Sbjct: 52 NE----EGVGAAIAASGIARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLV 107
Query: 413 HWPIGLNADYSHS 451
HWP +Y H+
Sbjct: 108 HWPTPAADNYVHA 120
>UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep:
Yarrowia lipolytica chromosome B of strain CLIB122 of
Yarrowia lipolytica - Yarrowia lipolytica (Candida
lipolytica)
Length = 337
Score = 95.5 bits (227), Expect = 1e-18
Identities = 55/129 (42%), Positives = 78/129 (60%), Gaps = 1/129 (0%)
Frame = +2
Query: 50 TMEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAI-DVG*RHFDTASV 226
TM +NNG+ +PAIG GT+ KS +++ V A+ + G RH DTA
Sbjct: 28 TMTSLDFTLNNGKTIPAIGLGTW---------KSTTEEVAGAVECALTEGGYRHIDTAFN 78
Query: 227 YETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLY 406
Y E +K +E+GV KREDIF+TTK+W T H R E + ++ SL++LGLDY+D+
Sbjct: 79 YRNEDAVGLGIKRAMEKGV-KREDIFVTTKIWVTYHDRVE--ENLDMSLERLGLDYVDML 135
Query: 407 LMHWPIGLN 433
L+HWP+ LN
Sbjct: 136 LIHWPVPLN 144
Score = 35.9 bits (79), Expect = 0.94
Identities = 16/35 (45%), Positives = 22/35 (62%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G K IG+SNF+ LE +LKE + P Q+E+H
Sbjct: 182 GKTKSIGVSNFSIPYLEELLKEAEVVPAVNQVELH 216
>UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Photorhabdus luminescens subsp. laumondii
Length = 292
Score = 95.1 bits (226), Expect = 1e-18
Identities = 52/152 (34%), Positives = 87/152 (57%)
Frame = +2
Query: 62 PSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETET 241
P +++ +G MP +G G++ S D+Q+ + + A+D+G R DTA++Y E
Sbjct: 5 PIIRLADGNHMPQLGLGSWA---------SDDQQIAETIHAALDIGYRAIDTAAIYNNE- 54
Query: 242 RNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 421
+ V ++E + REDIF+TTKLWN +H + A+ +SL+KL LDY+DLYL+HWP
Sbjct: 55 ---KGVGNALQETDIPREDIFVTTKLWNDRH--LDARAALTESLEKLQLDYVDLYLIHWP 109
Query: 422 IGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
Y + W+ L + Q+ G++++
Sbjct: 110 APPQDQY-------VGAWQQLIELQKEGLIRS 134
Score = 37.5 bits (83), Expect = 0.31
Identities = 20/60 (33%), Positives = 33/60 (55%), Gaps = 2/60 (3%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSKTFRKKW--WNFVSLKVL*SWAIL 675
G I+ IG+SNF + ++R++ E + P QIE+H +++ WN V SW+ L
Sbjct: 130 GLIRSIGVSNFQPEHIQRLINETGVHPVINQIELHPLLQQRQLHAWNATHNIVTESWSPL 189
>UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep:
Aldehyde reductase - gamma proteobacterium HTCC2207
Length = 330
Score = 95.1 bits (226), Expect = 1e-18
Identities = 51/129 (39%), Positives = 73/129 (56%)
Frame = +2
Query: 44 ASTMEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTAS 223
+ ++VP +K+++ + MPA+G G + K V AI VG RH D+A+
Sbjct: 2 SDAIQVPGVKVSS-KSMPAVGLGLW---------KITQDSAAQAVYEAIKVGYRHLDSAA 51
Query: 224 VYETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDL 403
Y E + + + EG+ RE+++ITTKLWNT HR V A S+ LGLDYIDL
Sbjct: 52 DYGNEQQVGEGIARAIAEGLCSREELWITTKLWNTYHRAEHVEAACRRSMDDLGLDYIDL 111
Query: 404 YLMHWPIGL 430
YL+H+PI L
Sbjct: 112 YLVHFPIAL 120
>UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase
1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent
oxidoreductase 1 - Oryza sativa subsp. japonica (Rice)
Length = 321
Score = 95.1 bits (226), Expect = 1e-18
Identities = 58/168 (34%), Positives = 90/168 (53%), Gaps = 10/168 (5%)
Frame = +2
Query: 44 ASTMEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTAS 223
A+ EVP+ ++ + MP +G GT F S+D ++RAI++G RHFDTA
Sbjct: 2 ATIPEVPASELI--QTMPRVGMGT-AAFP---FTSSEDTTA--AMLRAIELGYRHFDTAR 53
Query: 224 VYETETRNWRTVKMKVEEGVV-KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYID 400
+Y TE V V G++ R D+F+T+K+W + V A ++L+ LG+DY+D
Sbjct: 54 IYATEGCVGEAVAEAVRRGLIASRADVFVTSKIWCSDLHAGRVVPAARETLRNLGMDYVD 113
Query: 401 LYLMHWPIGL---NADYSH------SDVDFMETWRGLEDAQRMGILKA 517
L L+HWP+ L N D+ D WRG+E+ R+G+ +A
Sbjct: 114 LLLVHWPVSLTPGNYDFPFPKEVILPSFDMEGVWRGMEECHRLGLARA 161
Score = 34.7 bits (76), Expect = 2.2
Identities = 14/39 (35%), Positives = 25/39 (64%)
Frame = +1
Query: 490 CSANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
C G + IG+SNF+ ++LE++L ++P Q+EV+
Sbjct: 153 CHRLGLARAIGVSNFSAKKLEQLLSLAAVRPAVNQVEVN 191
>UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 293
Score = 94.7 bits (225), Expect = 2e-18
Identities = 54/153 (35%), Positives = 82/153 (53%)
Frame = +2
Query: 56 EVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYET 235
++P L MNNG +P +G G + V ++D ++ + A+ G RH DTA+ Y
Sbjct: 10 DIPDLPMNNGHQIPQLGLGVFQ------VDNAEDT--KNAIKWALAAGYRHIDTAAYYGN 61
Query: 236 ETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 415
E W V + E V R+ IF+T+KLWN+ E A ++L KLGLDY+DLYL+H
Sbjct: 62 E--QW--VGEAIRESDVPRDQIFVTSKLWNSVRGYDETQAAFQETLDKLGLDYLDLYLIH 117
Query: 416 WPIGLNADYSHSDVDFMETWRGLEDAQRMGILK 514
WP ++++WR +ED + G +K
Sbjct: 118 WPA----------PGYLDSWRAMEDLYKAGKIK 140
Score = 43.6 bits (98), Expect = 0.005
Identities = 19/35 (54%), Positives = 24/35 (68%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G IK IG+SNFN+ Q+ +L GT+KP QIE H
Sbjct: 137 GKIKNIGVSNFNQTQMADILAHGTVKPVVDQIETH 171
>UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 303
Score = 94.7 bits (225), Expect = 2e-18
Identities = 61/158 (38%), Positives = 85/158 (53%), Gaps = 8/158 (5%)
Frame = +2
Query: 68 LKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRN 247
L +NNG +P IG GTY +GV K A++ G R DTA VY E
Sbjct: 2 LALNNGHSIPPIGLGTYKITGSDGVAAIKS---------AVEFGYRLIDTAFVYNNEQVV 52
Query: 248 WRTVKMKVEEGV-VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
+ ++ +G + RED+FI +KL T HR V + SL++LGLDY+DLYLMH P+
Sbjct: 53 GQALREIFSQGNDINREDVFIVSKLGPTFHRPEAVEKGCRLSLERLGLDYVDLYLMHTPV 112
Query: 425 -----GLNADYSHSD--VDFMETWRGLEDAQRMGILKA 517
G D S D V +ETW+ LE+ QR G++++
Sbjct: 113 AARDSGDGNDRSEIDDEVTPLETWKALEECQRKGLVRS 150
Score = 40.7 bits (91), Expect = 0.033
Identities = 15/37 (40%), Positives = 25/37 (67%)
Frame = +1
Query: 490 CSANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIE 600
C G ++ IG+SNFN++QL ++ G+I+P Q+E
Sbjct: 142 CQRKGLVRSIGVSNFNEEQLMEIVTHGSIRPVVNQVE 178
>UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy
chain; n=3; Saccharomycetaceae|Rep: D-arabinose
dehydrogenase [NAD(P)+] heavy chain - Saccharomyces
cerevisiae (Baker's yeast)
Length = 344
Score = 94.7 bits (225), Expect = 2e-18
Identities = 51/117 (43%), Positives = 70/117 (59%)
Frame = +2
Query: 74 MNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWR 253
+NNG +PA+G GT + K + + V AI G RH DTA YETE
Sbjct: 27 LNNGVRIPALGLGTANPHE-------KLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGE 79
Query: 254 TVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
+K +E+G +KRED+FITTK+W EV +++N+SLK LGL+Y+DL L HWP+
Sbjct: 80 AIKELLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPL 134
Score = 38.7 bits (86), Expect = 0.13
Identities = 15/33 (45%), Positives = 24/33 (72%)
Frame = +1
Query: 508 IKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
++ IG+SNF+ + LER++KE +KP Q+E H
Sbjct: 186 VRAIGVSNFSIEYLERLIKECRVKPTVNQVETH 218
>UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus
tropicalis|Rep: LOC594893 protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 345
Score = 93.9 bits (223), Expect = 3e-18
Identities = 57/177 (32%), Positives = 93/177 (52%), Gaps = 26/177 (14%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFD---------------QNGVVKSKDKQLRDVVMRAIDVG 199
S+++++GR MP + GT+ F ++G KS +R A+D+G
Sbjct: 8 SIQLHDGRWMPVVAFGTFYPFTFPGDSQANPGHCAGTKHGTEKSFIDDVRVATKMALDLG 67
Query: 200 *RHFDTASVYETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKK 379
RH D A +Y +ET + + K +G +KRED+F T+KLWNT H+ V A+ +L
Sbjct: 68 YRHVDGAFLYSSETGVGQAFREKFADGTLKREDLFYTSKLWNTFHQPHLVRPALEKTLSF 127
Query: 380 LGLDYIDLYLMHWPIGL---------NAD--YSHSDVDFMETWRGLEDAQRMGILKA 517
L +DY+DLYL+H P+ N D + D ++TW+ LE+ + G++K+
Sbjct: 128 LQMDYVDLYLIHMPMSFKPAEELFPKNEDGTCAFDQPDLLQTWQALEECRDAGLVKS 184
Score = 40.7 bits (91), Expect = 0.033
Identities = 24/56 (42%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
Frame = +1
Query: 490 CSANGYIKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHSKTFRKKWWNFVSLK 651
C G +K IG+SNFN++QLE +L K G KP QIE H +K+ F K
Sbjct: 176 CRDAGLVKSIGVSNFNRRQLEMILNKPGLKYKPVCNQIECHPYLNQKQMLEFCKSK 231
>UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Staphylococcus|Rep: Oxidoreductase,
aldo/keto reductase family - Staphylococcus epidermidis
(strain ATCC 35984 / RP62A)
Length = 279
Score = 93.9 bits (223), Expect = 3e-18
Identities = 54/148 (36%), Positives = 81/148 (54%)
Frame = +2
Query: 74 MNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWR 253
+NNG MPA+G G Y K D+Q+ +VV A+D G R FDTA Y E +
Sbjct: 8 LNNGYPMPAVGLGVY---------KIADEQMEEVVRTALDAGYRAFDTAYFYGNE----K 54
Query: 254 TVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 433
+ ++ V+R+++FIT+KLWN + + N SL LGLDY+DL+L+HWP
Sbjct: 55 ALGSALKHSNVERDELFITSKLWNDYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWP---- 110
Query: 434 ADYSHSDVDFMETWRGLEDAQRMGILKA 517
+D ++E+++ LE G +KA
Sbjct: 111 ---CENDQLYIESYKALEHLYEEGKIKA 135
Score = 37.5 bits (83), Expect = 0.31
Identities = 17/35 (48%), Positives = 22/35 (62%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G IK IG+ NF LE+++KE I P QIE+H
Sbjct: 131 GKIKAIGVCNFKIHHLEKLMKETKITPQVNQIELH 165
>UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 337
Score = 93.9 bits (223), Expect = 3e-18
Identities = 48/148 (32%), Positives = 77/148 (52%), Gaps = 3/148 (2%)
Frame = +2
Query: 80 NGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTV 259
NG +P +G GT+ K++ ++RD V A+ G H D A+ Y E+ +
Sbjct: 12 NGLRIPRVGLGTW---------KARPNEVRDAVRDALGAGYAHVDCAAAYANESEVGEAL 62
Query: 260 KMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNAD 439
+ E G KRED+F+T+KLWN + R +V +A+ +L LG+ Y+DLYL+HWP+
Sbjct: 63 REAFERGDAKREDVFVTSKLWNDRRRPRDVREALMTTLNDLGVGYLDLYLIHWPVAWKRG 122
Query: 440 ---YSHSDVDFMETWRGLEDAQRMGILK 514
++ E W LE G+++
Sbjct: 123 TVLQPDAEASIAECWSELERCVADGLVR 150
Score = 35.5 bits (78), Expect = 1.2
Identities = 18/46 (39%), Positives = 28/46 (60%), Gaps = 2/46 (4%)
Frame = +1
Query: 475 ARIGRCSANGYIKGIGLSNFNKQQLERVLKE--GTIKPDAIQIEVH 606
+ + RC A+G ++ IG+SNFN+ QL + + I+P QIE H
Sbjct: 138 SELERCVADGLVRHIGVSNFNEAQLAALCDDPRTKIQPACNQIESH 183
>UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like
protein 1; n=14; Eutheria|Rep: Aldo-keto reductase
family 1 member C-like protein 1 - Homo sapiens (Human)
Length = 302
Score = 93.9 bits (223), Expect = 3e-18
Identities = 51/122 (41%), Positives = 73/122 (59%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
S+++N+G MP +G GTY + KS+ + V AIDVG RH D+A +Y+ E
Sbjct: 10 SVRLNDGPFMPVLGFGTYA---PDHTPKSQAAEATKV---AIDVGFRHIDSAYLYQNEEE 63
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
+ + K+ +G VKRE+IF T KLW T R V A+ SLKKLG DY+DL+++H P
Sbjct: 64 VGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPF 123
Query: 425 GL 430
+
Sbjct: 124 AM 125
>UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC
700755|Rep: YvgN - Psychroflexus torquis ATCC 700755
Length = 280
Score = 93.5 bits (222), Expect = 4e-18
Identities = 55/150 (36%), Positives = 89/150 (59%), Gaps = 2/150 (1%)
Frame = +2
Query: 74 MNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWR 253
+N+G +P +G GTY ++ G+ KS K A+ +G R DT ++Y+ E +
Sbjct: 5 LNDGNRIPIVGFGTYKANEEEGI-KSIQKS-------ALTLGYRLIDTVAIYQNEEAVGK 56
Query: 254 TVKMKVEEGVVKREDIFITTKLW--NTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 427
+K + GV+ RE+IF+TTKLW N +++T +A +++SL+KL L+YIDLYL+HWP
Sbjct: 57 AIKAR---GVL-REEIFVTTKLWRENLGYKQTRIA--LDESLRKLDLNYIDLYLIHWPAN 110
Query: 428 LNADYSHSDVDFMETWRGLEDAQRMGILKA 517
+Y +TWR +E+ Q G +K+
Sbjct: 111 A-INYKDWQKTNADTWRAMEELQAEGKIKS 139
Score = 34.3 bits (75), Expect = 2.9
Identities = 15/37 (40%), Positives = 21/37 (56%)
Frame = +1
Query: 496 ANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
A G IK +G+SNF + LE + + + P QIE H
Sbjct: 133 AEGKIKSLGVSNFWPEHLEALFQTAKVSPSVNQIEFH 169
>UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1;
Orconectes limosus|Rep: Aldoketoreductase-like protein -
Orconectes limosus (Spinycheek crayfish)
Length = 336
Score = 93.5 bits (222), Expect = 4e-18
Identities = 47/125 (37%), Positives = 78/125 (62%)
Frame = +2
Query: 56 EVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYET 235
++P++ +N+G +P +G GT +NG K ++ + V+ A++ G RHFD+A+ Y
Sbjct: 10 KIPTILLNSGSHIPVMGLGTG-SLGRNG--KMSEEAVTAVLETALECGYRHFDSAAYYGN 66
Query: 236 ETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 415
E + ++ + EG VKRE++FITTKL +R +VA+ + SL L L Y+DLYL+H
Sbjct: 67 EAIIGQVLRRWISEGKVKREELFITTKLPTRGNREKDVARFLQKSLDNLRLPYVDLYLVH 126
Query: 416 WPIGL 430
+P G+
Sbjct: 127 YPCGI 131
Score = 44.0 bits (99), Expect = 0.004
Identities = 18/37 (48%), Positives = 26/37 (70%)
Frame = +1
Query: 496 ANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
A G K IGLSNFN Q++R++K ++P +Q+EVH
Sbjct: 164 AAGKTKNIGLSNFNADQVQRIIKGCQVRPAVLQVEVH 200
>UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2;
Ascomycota|Rep: Aldo/keto reductase family proteins -
Aspergillus oryzae
Length = 323
Score = 93.5 bits (222), Expect = 4e-18
Identities = 49/120 (40%), Positives = 71/120 (59%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
+ K+N+G ++PAIG GT+L SK ++ + V A+ G RH D A+ Y+ E
Sbjct: 6 TFKLNSGYNIPAIGLGTWL---------SKPHEVENAVEAALRAGYRHIDAAACYQNENE 56
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
V ++ V R+ IFIT+KLWNT H V +A+N +LK L DY+DLYL+HWP+
Sbjct: 57 ----VGNGWKKSGVPRDQIFITSKLWNTHHHPEHVEEAVNKTLKDLQTDYLDLYLIHWPV 112
Score = 33.5 bits (73), Expect = 5.0
Identities = 14/33 (42%), Positives = 21/33 (63%)
Frame = +1
Query: 508 IKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
I+ IG+SNF + +++ +LK I P QIE H
Sbjct: 154 IRSIGISNFTQDKIDDLLKTAKIPPAVNQIEAH 186
>UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep:
Aldehyde reductase 1 - Sporobolomyces salmonicolor
Length = 323
Score = 93.5 bits (222), Expect = 4e-18
Identities = 48/122 (39%), Positives = 72/122 (59%)
Frame = +2
Query: 59 VPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETE 238
V + +N G + +G GT+ ++ ++ V AI+ G RH D A VY +
Sbjct: 2 VGTTTLNTGASLELVGYGTW---------QAAPGEVGQGVKVAIETGYRHLDLAKVYSNQ 52
Query: 239 TRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 418
V ++E VKRED+FIT+KLWN HR +V A++D+LK+LGL+Y+DLYL+HW
Sbjct: 53 PE----VGAAIKEAGVKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHW 108
Query: 419 PI 424
P+
Sbjct: 109 PV 110
>UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452
protein; n=6; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to LOC553452 protein -
Strongylocentrotus purpuratus
Length = 321
Score = 93.1 bits (221), Expect = 6e-18
Identities = 53/157 (33%), Positives = 85/157 (54%), Gaps = 12/157 (7%)
Frame = +2
Query: 83 GRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVK 262
GR +P +G GT+ + K +++ V+ AID G RH D AS+Y E +K
Sbjct: 13 GRKLPLLGFGTW---------QIKPEEVGRVIETAIDCGYRHIDEASLYGNEKGVGDGIK 63
Query: 263 MKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP---IGLN 433
K+++G +KRED+F+T+KLW T + V + SL LGL Y+DL+L+H P +G
Sbjct: 64 AKIDDGTIKREDLFVTSKLWVTDSHPSRVEPSCRQSLSDLGLAYLDLFLIHCPTSAVGGK 123
Query: 434 ADYSHSD---------VDFMETWRGLEDAQRMGILKA 517
+ D +D+++TWR +E G+++A
Sbjct: 124 GPFPMDDNGLFIGDDTIDYVDTWRIMESLVDKGLVRA 160
>UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase
family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto
reductase family - Enterococcus faecalis (Streptococcus
faecalis)
Length = 279
Score = 93.1 bits (221), Expect = 6e-18
Identities = 54/151 (35%), Positives = 81/151 (53%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
++ +NNG +P +G G + + D++ VV I G R DTA +Y E+
Sbjct: 8 TVTLNNGTKIPGMGLGVF---------QIPDEETAKVVEEGIINGYRLIDTAQIYGNESG 58
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
+K + + RED+F+T+K+WN E QA NDSL++LGLDY+DLYL+HWP
Sbjct: 59 TGAGIKAGLAATGLNREDLFVTSKVWNAHISYDETIQAFNDSLERLGLDYLDLYLIHWP- 117
Query: 425 GLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
G N+ + E+W+ LE G +KA
Sbjct: 118 GNNS--------YKESWQALETLYAEGKVKA 140
Score = 36.7 bits (81), Expect = 0.54
Identities = 18/48 (37%), Positives = 27/48 (56%)
Frame = +1
Query: 496 ANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSKTFRKKWWNF 639
A G +K IG+SNF LE +L + P Q+E+H K +K+ +F
Sbjct: 134 AEGKVKAIGVSNFQVHHLEDLLSYAKVVPVINQVELHPKLDQKEVRDF 181
>UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 323
Score = 93.1 bits (221), Expect = 6e-18
Identities = 58/167 (34%), Positives = 92/167 (55%), Gaps = 12/167 (7%)
Frame = +2
Query: 53 MEVPS-LKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVY 229
M +PS +N G +PA+G GT+ ++K ++ + V A+ G RH D A++Y
Sbjct: 1 MSLPSHFTINTGAKIPAVGFGTW---------QAKPLEVENAVEVALREGYRHIDCAAIY 51
Query: 230 ETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 409
ET V + + V RE+IFIT KLWNT+H +V A++ +L+ LG+ Y+DLYL
Sbjct: 52 RNETE----VGNGIRKSGVPREEIFITGKLWNTKHAPEDVEPALDKTLQDLGVAYLDLYL 107
Query: 410 MHWPIG---------LNAD--YSHSDVDFMETWRGLEDAQRMGILKA 517
MHWP LN D + +++D++ T+R +E G ++A
Sbjct: 108 MHWPCAFKGGDKWFPLNDDGVFDLANIDYITTYRAMEKLLATGKVRA 154
Score = 37.1 bits (82), Expect = 0.41
Identities = 16/37 (43%), Positives = 25/37 (67%)
Frame = +1
Query: 496 ANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
A G ++ IG+SNFN ++LE +L + ++ P QIE H
Sbjct: 148 ATGKVRAIGVSNFNIRRLEELLGQVSVVPAVNQIEAH 184
>UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:
Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 92.7 bits (220), Expect = 8e-18
Identities = 43/122 (35%), Positives = 70/122 (57%), Gaps = 11/122 (9%)
Frame = +2
Query: 185 AIDVG*RHFDTASVYETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAIN 364
AI G RH DTA Y E ++ K+++G+++R+D+FI +KLW T H ++ N
Sbjct: 9 AIAAGYRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPEDIPVCFN 68
Query: 365 DSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIL 511
SL L LDY+D YL+H+P+GL + +D+D+++ WRG+E + G +
Sbjct: 69 KSLSDLQLDYLDQYLVHFPVGLKKVGDELFPERDGKILTTDIDYVDVWRGMEALKATGKV 128
Query: 512 KA 517
K+
Sbjct: 129 KS 130
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/37 (43%), Positives = 24/37 (64%)
Frame = +1
Query: 496 ANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
A G +K IG+SNF +Q++R+L I P Q+E+H
Sbjct: 124 ATGKVKSIGVSNFTMEQIDRLLSVAKIPPAVNQVELH 160
>UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep:
Aldose reductase - Magnaporthe grisea (Rice blast
fungus) (Pyricularia grisea)
Length = 312
Score = 92.7 bits (220), Expect = 8e-18
Identities = 50/122 (40%), Positives = 71/122 (58%)
Frame = +2
Query: 74 MNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWR 253
+N G +PA G GT+ G GV+K + V+ AI G R D A VY E +
Sbjct: 8 LNTGAKIPAFGLGTWQG--DKGVIK-------EAVLTAIKSGYRLIDGAYVYGNEEEVGQ 58
Query: 254 TVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 433
++ + G+VKRED+F+ +K W T R E+ ++ SLK LGLDY+DLYL+HWPI +N
Sbjct: 59 GIREAISSGIVKREDLFVVSKCWATYTTRCEL--GLDQSLKLLGLDYVDLYLVHWPILMN 116
Query: 434 AD 439
+
Sbjct: 117 PE 118
Score = 34.3 bits (75), Expect = 2.9
Identities = 17/52 (32%), Positives = 29/52 (55%)
Frame = +1
Query: 496 ANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSKTFRKKWWNFVSLK 651
A G K +G+SN++K LE++L T P Q+E H + +++ +F K
Sbjct: 152 ATGKTKAVGVSNYSKAWLEQLLPHATTVPAVNQVENHPQLPQQELVDFCKEK 203
>UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 339
Score = 92.7 bits (220), Expect = 8e-18
Identities = 53/127 (41%), Positives = 74/127 (58%)
Frame = +2
Query: 59 VPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETE 238
+PS +N G +P++G G + G Q G +D +L D ++RAI VG RH DTA+ Y
Sbjct: 5 IPSFTLNTGAKLPSVGMGCWQG--QPG--PGRDNELVDALVRAIKVGYRHLDTATGY--- 57
Query: 239 TRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 418
RN V V + V R +IF+TTKL +V Q + +SL +LG+DYIDL+L+HW
Sbjct: 58 -RNEAEVGQAVRQSGVARSEIFVTTKL--RPGGVHDVVQELENSLNELGIDYIDLWLLHW 114
Query: 419 PIGLNAD 439
P G D
Sbjct: 115 PQGFTKD 121
Score = 34.3 bits (75), Expect = 2.9
Identities = 16/38 (42%), Positives = 22/38 (57%)
Frame = +1
Query: 493 SANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
S G +K IG+SNF+ + LE + K + P QIE H
Sbjct: 157 SHKGKVKAIGVSNFSIKNLEILAKTSKVTPAVNQIEAH 194
>UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several
dehydrogenases of different specificities; n=4;
Pezizomycotina|Rep: Similarity: shows similarity to
several dehydrogenases of different specificities -
Aspergillus niger
Length = 381
Score = 92.3 bits (219), Expect = 1e-17
Identities = 46/118 (38%), Positives = 72/118 (61%), Gaps = 1/118 (0%)
Frame = +2
Query: 74 MNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWR 253
+N+G +P +G GT+ +S Q+ D V A+ G RH D A++Y+ +
Sbjct: 9 LNSGAQIPQLGFGTW---------QSAPGQVGDAVYEALKAGYRHLDLATIYQNQREVAE 59
Query: 254 TVKMKVEEGV-VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
+K ++ +KREDIFIT+KLWN+QH V +A+++ L +L LDY+DLYL+HWP+
Sbjct: 60 GIKRAYKDVPGLKREDIFITSKLWNSQHDPAVVEKALDECLAELELDYLDLYLVHWPV 117
>UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5;
Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative
- Neosartorya fischeri (strain ATCC 1020 / DSM 3700 /
NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 /
DSM 3700 / NRRL 181))
Length = 321
Score = 92.3 bits (219), Expect = 1e-17
Identities = 49/126 (38%), Positives = 67/126 (53%)
Frame = +2
Query: 53 MEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYE 232
M PS K+N+G DMP +G G + K ++ D + AI G R FD A Y
Sbjct: 1 MTTPSTKLNSGYDMPLVGFGLW---------KVNNETCADQIYHAIKAGYRLFDGACDYG 51
Query: 233 TETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 412
E + V ++EG+VKRED+FI +KLWN+ H V L GLDY DL+++
Sbjct: 52 NEVEAGKGVARAIQEGIVKREDLFIVSKLWNSFHDGDRVEPICRKQLADWGLDYFDLFIV 111
Query: 413 HWPIGL 430
H+PI L
Sbjct: 112 HFPIAL 117
>UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein;
n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9
protein - Oryza sativa (Rice)
Length = 337
Score = 91.9 bits (218), Expect = 1e-17
Identities = 59/171 (34%), Positives = 86/171 (50%), Gaps = 13/171 (7%)
Frame = +2
Query: 44 ASTMEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTAS 223
A+ VP + +N+G MP +G GT + L + A+ +G RH DTA+
Sbjct: 15 AAATAVPCVTLNSGHAMPVLGFGTGSS--------TPPADLAATIAHAVRLGYRHLDTAA 66
Query: 224 VYETETRNWRTVKMKVEEGVV-KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYID 400
VY TE V V G V R ++F+TTKL V A+ +SL +LGLDY+D
Sbjct: 67 VYGTEGAVGAAVAEAVRCGAVASRGELFVTTKLSMADAHPPRVVAALRESLSRLGLDYVD 126
Query: 401 LYLMHWPIGLNA----------DYSHSDVDF-ME-TWRGLEDAQRMGILKA 517
L+L+HWP+ + D S V F ME WRG+E+ R+G+ ++
Sbjct: 127 LFLIHWPVAIGKKDAAGELTWDDLSRGLVPFDMEGVWRGMEECHRLGLARS 177
>UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 321
Score = 91.9 bits (218), Expect = 1e-17
Identities = 56/167 (33%), Positives = 89/167 (53%), Gaps = 16/167 (9%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
+ K+N+G +P+IG GTY + +N ++ D + A+ G RH D A+ Y E
Sbjct: 16 NFKLNDGNQIPSIGLGTY--YSEN------PGEVGDAINNALKNGYRHIDGAAFYGNEKV 67
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
++K +EG +KREDIF T+KLWN+ H V + +++ LG+ Y+DLYL+HWPI
Sbjct: 68 IGNSLKEIFKEGEIKREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPI 127
Query: 425 --------GL--------NADYSHSDVDFMETWRGLEDAQRMGILKA 517
GL N + + V ETW+ +E +G++K+
Sbjct: 128 AFENSNPLGLTIEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKS 174
Score = 37.9 bits (84), Expect = 0.23
Identities = 17/35 (48%), Positives = 22/35 (62%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G +K IG+SNFN Q L +L IKP Q+E+H
Sbjct: 170 GLVKSIGVSNFNVQNLVDLLTYAKIKPVVNQVEIH 204
>UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 322
Score = 91.5 bits (217), Expect = 2e-17
Identities = 54/149 (36%), Positives = 78/149 (52%)
Frame = +2
Query: 68 LKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRN 247
+K+NNG+++P + G Y D + A D G RH D+A+ Y E
Sbjct: 19 IKLNNGQEIPQVALGVYKA--------PNDGSTENACKWAFDAGYRHIDSAARYMNEESV 70
Query: 248 WRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 427
R + +E V R +IFIT+KLW+ H + A AI DSLKKL +DY+D+YLMH P
Sbjct: 71 GRALAEWTKENNVPRSEIFITSKLWDADH--DKAAAAIEDSLKKLNVDYMDMYLMHSPGT 128
Query: 428 LNADYSHSDVDFMETWRGLEDAQRMGILK 514
+ A+ +E W+ LE+A G +K
Sbjct: 129 MGAEKR------LEAWKALEEAVDAGKIK 151
Score = 35.5 bits (78), Expect = 1.2
Identities = 17/35 (48%), Positives = 23/35 (65%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G IK IG+SNF+ ++L+ +L IKP QIE H
Sbjct: 148 GKIKTIGVSNFDVEELDHLLANCRIKPAVNQIESH 182
>UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 360
Score = 91.5 bits (217), Expect = 2e-17
Identities = 48/140 (34%), Positives = 82/140 (58%), Gaps = 1/140 (0%)
Frame = +2
Query: 95 PAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKVE 274
P IG GT+ +K + + V AI++G R D A+VY E R ++ ++
Sbjct: 40 PLIGFGTWN-------LKVSPENTTEAVAYAIEIGYRQIDCAAVYGNEVAVGRGIEEGLK 92
Query: 275 EGVVKREDIFITTKLWNTQHRRTE-VAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHS 451
+KREDI++T+KLWN H E V + +N +L+ LGL+Y+DLYL+HWPIG +++
Sbjct: 93 RAGLKREDIWVTSKLWNDHHGSYENVEKGLNQTLQDLGLEYLDLYLIHWPIGFSSN-GAK 151
Query: 452 DVDFMETWRGLEDAQRMGIL 511
++D ++T++ + + +L
Sbjct: 152 NLDHVQTYKSMISLPKSRVL 171
>UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep:
CG2767-PA - Drosophila melanogaster (Fruit fly)
Length = 329
Score = 91.1 bits (216), Expect = 2e-17
Identities = 49/122 (40%), Positives = 69/122 (56%)
Frame = +2
Query: 68 LKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRN 247
L NNG MP IG GT+ ++ D+++ + A++ G RH DTA VY E
Sbjct: 7 LTFNNGEKMPVIGIGTW---------QASDEEIETAIDAALEAGYRHIDTAPVYGNEKAI 57
Query: 248 WRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 427
R +K ++ G VKRE++FI TK+ +R EV I SL+ L LDY+DLYL+H P
Sbjct: 58 GRVLKRWLDAGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFT 117
Query: 428 LN 433
+N
Sbjct: 118 IN 119
Score = 37.5 bits (83), Expect = 0.31
Identities = 18/35 (51%), Positives = 23/35 (65%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G K IG+SNF+K Q+ R+LK I+P QIE H
Sbjct: 156 GLTKSIGVSNFSKDQVARLLKNCKIRPANNQIEHH 190
>UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep:
Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 90.6 bits (215), Expect = 3e-17
Identities = 54/159 (33%), Positives = 83/159 (52%), Gaps = 2/159 (1%)
Frame = +2
Query: 47 STMEVPSLKMNNGRDMPAIGXGT--YLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTA 220
+ + P++ ++NG ++P +G GT Y G+ V+ + + G RH DTA
Sbjct: 9 TALSCPAVPLHNGLNIPILGLGTSHYGGYSHEAVLYALQ-----------ECGIRHIDTA 57
Query: 221 SVYETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYID 400
Y E + V E V+RE++++TTKLW + QA DS +LG+DY+D
Sbjct: 58 KRYGCE----EALGKAVTESGVQREELWVTTKLWPGDYGYQSTKQACRDSRARLGVDYLD 113
Query: 401 LYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
LYLMHWP + S +V +ETWR LE+ G+ +A
Sbjct: 114 LYLMHWPDSMVPGRSSQEVR-LETWRALEELYDEGLCRA 151
>UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep:
Lin2848 protein - Listeria innocua
Length = 280
Score = 90.2 bits (214), Expect = 4e-17
Identities = 54/149 (36%), Positives = 78/149 (52%)
Frame = +2
Query: 71 KMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNW 250
++NNG +MP G G Y D+ +++R + A+DVG R FDTAS Y E
Sbjct: 10 RLNNGIEMPRHGFGVYKLTDE--------QRMRTALETAVDVGYRLFDTASFYHNE---- 57
Query: 251 RTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 430
+ + +KR++ F+TTK+WNT+ E +A S KKL LD +DLYL+HWP
Sbjct: 58 KELGDFFASSGLKRDEFFVTTKMWNTEQGYDETLRAFEKSQKKLQLDQVDLYLVHWP--- 114
Query: 431 NADYSHSDVDFMETWRGLEDAQRMGILKA 517
F ETWR +E G+++A
Sbjct: 115 ------KQDTFFETWRAVEKLYDEGLVRA 137
>UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep:
Aldehyde reductase - Leptospira interrogans
Length = 278
Score = 90.2 bits (214), Expect = 4e-17
Identities = 44/121 (36%), Positives = 73/121 (60%), Gaps = 1/121 (0%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKD-KQLRDVVMRAIDVG*RHFDTASVYETET 241
++ +NNG MP +G G + K+K K+ ++ V+ A++ G RH DTA +Y+ E
Sbjct: 11 TIMLNNGISMPILGLGVW---------KTKSGKECKEAVLNALEAGYRHIDTARIYDNEV 61
Query: 242 RNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 421
V + E + R++IFITTKLWN + +A+ +SL +LG+D++DLYL+H+P
Sbjct: 62 ----DVGQAIRESGIPRKEIFITTKLWNADQGSDKTRKALENSLDRLGIDFVDLYLIHFP 117
Query: 422 I 424
+
Sbjct: 118 V 118
>UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 -
Mycoplasma gallisepticum
Length = 289
Score = 90.2 bits (214), Expect = 4e-17
Identities = 57/161 (35%), Positives = 87/161 (54%), Gaps = 4/161 (2%)
Frame = +2
Query: 47 STMEVPSLKMN---NGRDMPAIGXGTYLGFDQNGVVKSKD-KQLRDVVMRAIDVG*RHFD 214
+T ++ +K N N MP+IG GTY K +D KQ + V A++VG RH D
Sbjct: 4 TTKKIKVMKYNLLANNYKMPSIGFGTY---------KLEDGKQTVEAVKTALEVGYRHLD 54
Query: 215 TASVYETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDY 394
A +YE N +V ++ V R++IFIT+K+WN +A + LK L L+Y
Sbjct: 55 CAEIYE----NQLSVSQGIKLSGVNRKEIFITSKIWNDDKGYESTKKAFHKILKDLDLEY 110
Query: 395 IDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
+DL L+HWPIG + +V+ +TW+ +E+ G +KA
Sbjct: 111 LDLLLIHWPIGKGFKDNWQEVN-AQTWKAMEEFYLEGKIKA 150
>UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium
SCB49|Rep: ARA1 - unidentified eubacterium SCB49
Length = 280
Score = 90.2 bits (214), Expect = 4e-17
Identities = 47/149 (31%), Positives = 83/149 (55%)
Frame = +2
Query: 71 KMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNW 250
K+NN ++PAIG GT+ D + + + AID G +H D A++Y+ E
Sbjct: 6 KLNNNINIPAIGFGTWQTPDGQTAINA--------IKTAIDAGYKHIDAAAIYKNE---- 53
Query: 251 RTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 430
+ V + ++E + R+D+F+T+K+WN Q +A ++++ L LDY+DLYL+HWP
Sbjct: 54 KGVGLGIKEANIDRKDLFVTSKVWNEQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAA 113
Query: 431 NADYSHSDVDFMETWRGLEDAQRMGILKA 517
+ + ++ +TW +E + G +KA
Sbjct: 114 HQFENWKQLN-NDTWSAMEKLYKDGKIKA 141
Score = 37.5 bits (83), Expect = 0.31
Identities = 17/36 (47%), Positives = 23/36 (63%)
Frame = +1
Query: 499 NGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
+G IK +G+SNF + L +L+ TIKP QIE H
Sbjct: 136 DGKIKALGVSNFMEHHLTPLLQHATIKPTVNQIEYH 171
>UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core
eudicotyledons|Rep: T2K10.1 protein - Arabidopsis
thaliana (Mouse-ear cress)
Length = 176
Score = 89.4 bits (212), Expect = 7e-17
Identities = 57/169 (33%), Positives = 83/169 (49%), Gaps = 13/169 (7%)
Frame = +2
Query: 47 STMEVPSLKMNNG----RDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFD 214
S VP+L + +G MP +G GT + L++ V+ AI +G RHFD
Sbjct: 2 SLTTVPTLAIRSGPSGHHSMPVLGFGTAAS------PLPEPTMLKETVIEAIKLGYRHFD 55
Query: 215 TASVYETETRNWRTVKMKVEEGVVK-REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLD 391
T+ Y+TE + V G+V+ R + F+TTKLW V AI SLK L LD
Sbjct: 56 TSPRYQTEEPIGEALAEAVSLGLVRSRSEFFVTTKLWCADAHGGLVVPAIKRSLKNLKLD 115
Query: 392 YIDLYLMHWPIGLNA--------DYSHSDVDFMETWRGLEDAQRMGILK 514
Y+DLY++HWP+ + +DF W +E+ QR+G+ K
Sbjct: 116 YLDLYIIHWPVSSKPGKYKFPIDEDDFMPMDFEVVWSEMEECQRLGLAK 164
>UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase;
n=2; Parasitella parasitica|Rep:
4-dihydromethyltrisporate dehydrogenase - Parasitella
parasitica
Length = 321
Score = 89.4 bits (212), Expect = 7e-17
Identities = 46/113 (40%), Positives = 63/113 (55%)
Frame = +2
Query: 137 GVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKVEEGVVKREDIFITTK 316
G K + K + + +AI +G R FD A Y E R + ++EG+VKRE++FI TK
Sbjct: 21 GCWKIEKKDAENTIYQAIKIGYRLFDGACDYGNEVEVGRGINKAIKEGLVKREELFIVTK 80
Query: 317 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETW 475
LWNT H + V A + LK GL+Y DLYL+H+PI L Y V + W
Sbjct: 81 LWNTFHSKQHVRTAFDRQLKDWGLEYFDLYLIHFPIPL--QYVDPAVSYPPEW 131
Score = 33.5 bits (73), Expect = 5.0
Identities = 14/32 (43%), Positives = 21/32 (65%)
Frame = +1
Query: 511 KGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
+ IG++NFN Q + +L IKP +QIE+H
Sbjct: 163 RNIGVANFNCQAILDLLSYAKIKPAVLQIEIH 194
>UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7;
cellular organisms|Rep: Prostaglandin f synthase,
putative - Leishmania major
Length = 279
Score = 89.0 bits (211), Expect = 1e-16
Identities = 56/148 (37%), Positives = 75/148 (50%)
Frame = +2
Query: 74 MNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWR 253
++NG +P +G GT+ D N VV K A++ G RH DTA Y+ E +
Sbjct: 10 LSNGVQVPQLGIGTWEAKDGNEVVNIK---------WAVNAGYRHVDTAHYYKNE----K 56
Query: 254 TVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 433
V + E V R DIF+TTKLWN H A S + LG++Y+DLYL+HWP G N
Sbjct: 57 GVGQGISECGVPRSDIFVTTKLWNYDHGYESALAAFEQSRQALGVEYVDLYLIHWP-GPN 115
Query: 434 ADYSHSDVDFMETWRGLEDAQRMGILKA 517
Y +ETWR E M ++A
Sbjct: 116 RSY-------IETWRAFEKLYEMKKVRA 136
>UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8;
Saccharomycetaceae|Rep: Glycerol dehydrogenase -
Zygosaccharomyces rouxii (Candida mogii)
Length = 310
Score = 89.0 bits (211), Expect = 1e-16
Identities = 47/125 (37%), Positives = 74/125 (59%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
+LK+N G+ +P +G GT+ +SK+ + V+ A+ G RH D A+VY E
Sbjct: 10 TLKLNTGQTIPQVGLGTW---------RSKENEGYKAVIEALKAGYRHIDGAAVYGNEGE 60
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
V +++ V R +IF+TTKLW T R + +A++ SL++LGLDY+ LYL+HWP+
Sbjct: 61 ----VGKAIQDSGVPRNEIFLTTKLWCTHQRNPQ--EALDQSLQRLGLDYVGLYLVHWPV 114
Query: 425 GLNAD 439
L +
Sbjct: 115 PLRTE 119
>UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG03517.1 - Gibberella zeae PH-1
Length = 364
Score = 88.6 bits (210), Expect = 1e-16
Identities = 55/156 (35%), Positives = 83/156 (53%), Gaps = 3/156 (1%)
Frame = +2
Query: 56 EVPSLKMNNG-RDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYE 232
E+P N RD+PA G GT+L GVV V A+ G RH DTA ++
Sbjct: 47 EMPEFNKNETVRDIPAFGLGTWLA--GKGVVVP-------AVEYALKGGYRHIDTALIW- 96
Query: 233 TETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 412
RN V ++ V R++I++T KLWNT HR V +AI S+ LG++Y+DLYL+
Sbjct: 97 ---RNEDEVGKGIKASGVSRDEIWVTGKLWNTDHRPELVRKAIETSIANLGVEYLDLYLI 153
Query: 413 HWPIGLNADYSHSD--VDFMETWRGLEDAQRMGILK 514
H+P+ + D ++TW+ +E+ R G+ +
Sbjct: 154 HYPVAWVPETRDVDNNTSLIDTWKAMEELVRAGLTR 189
>UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14;
Dikarya|Rep: Aldo-keto reductase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 353
Score = 88.6 bits (210), Expect = 1e-16
Identities = 57/170 (33%), Positives = 88/170 (51%), Gaps = 15/170 (8%)
Frame = +2
Query: 53 MEVP-SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVY 229
M P S K+N G +PAIG GT+ ++K ++R V A+ G RH D A Y
Sbjct: 33 MSAPTSFKLNTGASIPAIGLGTW---------QAKAGEVRQAVAHALKAGYRHIDGALCY 83
Query: 230 ETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 409
+ E V + +++ V R +IF+T+K+W++ H R E + ++ +LK L DY+DLYL
Sbjct: 84 QNEDE----VGLGIKDSGVPRSEIFLTSKVWSSYHDRVE--ECLDTTLKSLQTDYLDLYL 137
Query: 410 MHWPIGLNADYSHS--------------DVDFMETWRGLEDAQRMGILKA 517
+HWP+ L + +H D D +TW +ED + G KA
Sbjct: 138 IHWPVRLAPNGTHPLFPVKPDGSRNLDWDWDQAKTWAQMEDVLKKGKAKA 187
>UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 339
Score = 88.2 bits (209), Expect = 2e-16
Identities = 52/167 (31%), Positives = 90/167 (53%), Gaps = 16/167 (9%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
++ +N+G +MP IG GT+ +N + ++RD A++ G RH D+A ++ +
Sbjct: 6 TVTLNSGYEMPVIGYGTWQ-LPKNLAAE----RVRD----ALEAGYRHIDSALSFKNQEE 56
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
+K + V+RE++F+++K+WNT H R Q I++ L+ Y+DL ++HWP
Sbjct: 57 VAAGIKDWCKIRKVRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIHWPF 116
Query: 425 ----------------GLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
G N +SDVD++ETW+ LEDA R G +++
Sbjct: 117 GWAEDEPPGERGLWPRGANGKMRYSDVDYLETWKALEDAHRSGKIRS 163
Score = 39.9 bits (89), Expect = 0.058
Identities = 17/36 (47%), Positives = 27/36 (75%)
Frame = +1
Query: 499 NGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
+G I+ IGL+NFN Q+E+V +G IKP +Q+E++
Sbjct: 158 SGKIRSIGLANFNIGQVEQVWTKGLIKPAVLQVEMN 193
>UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein T08H10.1 - Caenorhabditis elegans
Length = 333
Score = 88.2 bits (209), Expect = 2e-16
Identities = 57/168 (33%), Positives = 86/168 (51%), Gaps = 13/168 (7%)
Frame = +2
Query: 53 MEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRA-IDVG*RHFDTASVY 229
M V S+ +N G +P G GT+ + KD+ V +RA +D G R DTA +Y
Sbjct: 1 MTVDSIPLNTGAQLPLFGLGTW---------QVKDEAELTVALRAALDAGYRLIDTAHLY 51
Query: 230 ETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 409
+ E + + + G +KREDIF+T+KL T H +V + + LK L L+YIDLYL
Sbjct: 52 QNEHIIGKVLHEYISSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLYL 111
Query: 410 MHWPIGL------------NADYSHSDVDFMETWRGLEDAQRMGILKA 517
+H P N + + +++ ++TWR LE + G LKA
Sbjct: 112 IHCPFPFKHQEGSFAPLMENGELAVTEIAHIDTWRALEKLYKEGKLKA 159
>UniRef50_P22045 Cluster: Probable reductase; n=101; cellular
organisms|Rep: Probable reductase - Leishmania major
Length = 284
Score = 87.8 bits (208), Expect = 2e-16
Identities = 50/138 (36%), Positives = 72/138 (52%)
Frame = +2
Query: 74 MNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWR 253
++NG MP G G + + + V A+ G RH DTA++Y+ E
Sbjct: 11 LSNGVKMPQFGLGVWQS--------PAGEVTENAVNWALCAGYRHIDTAAIYKNE----E 58
Query: 254 TVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 433
+V + V RED+FITTKLWNT+ A +S +KLG+DYIDLYL+HWP G +
Sbjct: 59 SVGAGLRASGVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRGKD 118
Query: 434 ADYSHSDVDFMETWRGLE 487
S ++++WR E
Sbjct: 119 I-LSKEGKKYLDSWRAFE 135
>UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase
2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent
oxidoreductase 2 - Oryza sativa subsp. japonica (Rice)
Length = 322
Score = 87.4 bits (207), Expect = 3e-16
Identities = 52/152 (34%), Positives = 79/152 (51%), Gaps = 10/152 (6%)
Frame = +2
Query: 92 MPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKV 271
MP IG GT + ++ ++RAI++G RHFDTA +Y TE V V
Sbjct: 18 MPRIGMGTA------AFPFTSSEETTAALLRAIELGYRHFDTARLYATEGCVSEAVAEAV 71
Query: 272 EEGVV-KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL---NAD 439
G+V R D+F+T+KLW + V A ++L+ LG+DY+DL L+HWP + + D
Sbjct: 72 RRGLVASRADVFVTSKLWCSDLHAGRVVPAARETLRNLGMDYVDLLLVHWPATVAPGSYD 131
Query: 440 YSHSD------VDFMETWRGLEDAQRMGILKA 517
+ D WRG+E+ R+G+ +A
Sbjct: 132 FPFPKEEMAPAFDMEGVWRGMEECHRLGLARA 163
Score = 35.1 bits (77), Expect = 1.6
Identities = 14/39 (35%), Positives = 26/39 (66%)
Frame = +1
Query: 490 CSANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
C G + IG+SNF+ ++LE++L ++P A Q+E++
Sbjct: 155 CHRLGLARAIGVSNFSAKKLEQLLSFAVVRPAANQVEMN 193
>UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 323
Score = 87.0 bits (206), Expect = 4e-16
Identities = 52/160 (32%), Positives = 82/160 (51%), Gaps = 11/160 (6%)
Frame = +2
Query: 71 KMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNW 250
K+N G +PA+ GT+ +S +++ + V AI++G RH D A +Y E
Sbjct: 9 KLNTGASIPAMALGTW---------QSSKEEVGNAVRLAIELGYRHIDCAEIYGNEGEIG 59
Query: 251 RTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI-- 424
+ + EG VKRE++F+T+KLW H +V A +LK L LDY+DLYL+H P+
Sbjct: 60 EALSEVLTEGKVKREELFVTSKLWCDSHHPDDVLPACQATLKNLQLDYLDLYLIHIPVAF 119
Query: 425 --GLNADYS-------HSDVDFMETWRGLEDAQRMGILKA 517
G+ +S ++ TW+ +E G+ KA
Sbjct: 120 KKGVRLPHSIAEGIIGYTPEGVQNTWQAMEGLVAKGLCKA 159
Score = 36.7 bits (81), Expect = 0.54
Identities = 18/52 (34%), Positives = 30/52 (57%)
Frame = +1
Query: 496 ANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSKTFRKKWWNFVSLK 651
A G K IG+SNF+ ++L ++L+ +I P Q+E+H ++K F K
Sbjct: 153 AKGLCKAIGVSNFSVKRLNKLLETASIVPACNQVELHPYLPQEKLKEFCDSK 204
>UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6;
Pezizomycotina|Rep: Aldo/keto reductase family proteins
- Aspergillus oryzae
Length = 294
Score = 87.0 bits (206), Expect = 4e-16
Identities = 50/157 (31%), Positives = 85/157 (54%)
Frame = +2
Query: 47 STMEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASV 226
S P +K+N+ +P +G GT + + S +++L + + AI +G RH D A V
Sbjct: 5 SIPNTPRVKLNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGAEV 64
Query: 227 YETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLY 406
Y TE + + ++E + RE++F+TTK+ ++ AI+ SL+KL L+Y+DLY
Sbjct: 65 YGTEAE----LGVAIKESGIPREELFVTTKVITNI---ADIPSAIDQSLRKLQLNYVDLY 117
Query: 407 LMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
L+H P ++ SD + + W +E Q+ G KA
Sbjct: 118 LIHSPF-----FAKSDGELQQAWAAMEKVQQAGKAKA 149
Score = 33.1 bits (72), Expect = 6.6
Identities = 16/35 (45%), Positives = 20/35 (57%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G K IG+SN+++ LE LK I P QIE H
Sbjct: 145 GKAKAIGVSNYHQSHLEATLKTAVIAPVINQIEHH 179
>UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2;
Actinomycetales|Rep: Putative oxidoreductase -
Streptomyces coelicolor
Length = 277
Score = 86.6 bits (205), Expect = 5e-16
Identities = 46/129 (35%), Positives = 70/129 (54%)
Frame = +2
Query: 56 EVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYET 235
+VP + +NNG +MP +G G + + D + V A++ G R DTA++Y
Sbjct: 4 KVPPIILNNGVEMPQLGFGVW---------QVPDDDAQTAVALALEAGYRSIDTAAIYGN 54
Query: 236 ETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 415
E R + G+ RED+F+TTKLWN+ +A + S+ KLGL+Y+DLYL+H
Sbjct: 55 EEGTGRAI---AASGLA-REDLFVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYLDLYLIH 110
Query: 416 WPIGLNADY 442
WP+ Y
Sbjct: 111 WPMPAKERY 119
Score = 36.7 bits (81), Expect = 0.54
Identities = 16/37 (43%), Positives = 25/37 (67%)
Frame = +1
Query: 496 ANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
A+G ++ IG+SNF + LER+ E ++ P QIE+H
Sbjct: 131 ADGRVRAIGVSNFLPEHLERLTAETSVIPAVNQIELH 167
>UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 288
Score = 86.6 bits (205), Expect = 5e-16
Identities = 55/166 (33%), Positives = 85/166 (51%)
Frame = +2
Query: 56 EVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYET 235
+ P++ +N+GR +PAIG GT+ D ++ V A+ +G RH DTA Y
Sbjct: 3 KTPTITLNDGRAIPAIGFGTFQIPDDGSTYQA--------VKEALVIGYRHIDTAVAYFN 54
Query: 236 ETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 415
E V +++ + R+ I++T+KLW + ++AI+ SL KL LDYIDLYL+H
Sbjct: 55 EDE----VGQAIKDSGIPRDQIWVTSKLWLQDYGFDAASRAIDRSLTKLRLDYIDLYLIH 110
Query: 416 WPIGLNADYSHSDVDFMETWRGLEDAQRMGILKASDCLTSTSSSWR 553
P G D W+ +E AQ+ G LK+ T + W+
Sbjct: 111 QPYG----------DVPGAWQAMEAAQKAGKLKSIGVSNMTPTLWQ 146
>UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family;
n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto
reductase family - Lactobacillus acidophilus
Length = 289
Score = 86.6 bits (205), Expect = 5e-16
Identities = 53/154 (34%), Positives = 81/154 (52%)
Frame = +2
Query: 56 EVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYET 235
++P +K+N+G ++P +G G + + + VK+ V AI G R DTA Y
Sbjct: 3 DIPKIKLNDGNEIPQLGFGVFQISNHDEAVKA--------VESAISNGYRLIDTAEAYNN 54
Query: 236 ETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 415
+T V ++ V R+DIF+TTKLW + + ++AI++ LK+LG DYID+ L+H
Sbjct: 55 QT----AVGEAIKNSDVNRDDIFLTTKLWVSNFTYEKASKAIDEDLKELGTDYIDMMLLH 110
Query: 416 WPIGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
G D WR LEDAQ+ G K+
Sbjct: 111 QAYG----------DVAGAWRALEDAQKAGKTKS 134
>UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 310
Score = 85.8 bits (203), Expect = 9e-16
Identities = 56/162 (34%), Positives = 90/162 (55%), Gaps = 4/162 (2%)
Frame = +2
Query: 44 ASTMEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTAS 223
A T + L++NNG DMP +G GTY V+ ++ ++ V+ + VG R DTA
Sbjct: 18 ALTPTIRDLRLNNGYDMPLVGIGTYK-------VRGREV-IKRVIDESFAVGFRSIDTAV 69
Query: 224 VYETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTE-VAQAINDSLKKLGLDYID 400
VY E +K + + +KREDIFIT+KL + + + + +++ DSLK L Y+D
Sbjct: 70 VYRNEEDIGLALKELLPKYNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALDTSYLD 129
Query: 401 LYLMHWPIGLNADYSHSDVD---FMETWRGLEDAQRMGILKA 517
LYL+HWP G + +S + + TW L + Q+ G+L++
Sbjct: 130 LYLIHWP-GASRILENSPDNPKLRVTTWATLVELQQKGLLRS 170
>UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2;
Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid
reductase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 283
Score = 85.8 bits (203), Expect = 9e-16
Identities = 48/121 (39%), Positives = 66/121 (54%)
Frame = +2
Query: 59 VPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETE 238
VPS+ + +G +P G GTY + + VV AI++G RH DTAS+Y E
Sbjct: 9 VPSVLLGDGVSIPQFGLGTY---------ELPPNEASSVVQSAIELGYRHIDTASLYANE 59
Query: 239 TRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 418
R V + +KRE+ F+TTKLWN+ + +A SL L LDY+DLYL+HW
Sbjct: 60 ----REVGRAIASSGIKREEFFVTTKLWNSDQPKPR--EAFERSLDLLSLDYVDLYLIHW 113
Query: 419 P 421
P
Sbjct: 114 P 114
>UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 323
Score = 85.4 bits (202), Expect = 1e-15
Identities = 50/159 (31%), Positives = 88/159 (55%), Gaps = 5/159 (3%)
Frame = +2
Query: 56 EVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYET 235
++ +++NNG MP +G GT + V + +++ ++ A+D G R+FDTA Y
Sbjct: 11 DIKYVQLNNGYKMPLLGLGTQ---PYDIVTRVTVEEMTTLLSNALDFGYRNFDTAKQYRN 67
Query: 236 ETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 415
E + + ++G KRED+FITTKL+ + + ++ + + +SL +L YIDLYL+
Sbjct: 68 EVEIGQAFQNIFQQGKYKREDVFITTKLFPFKIEK-KIKEVVQNSLDQLQTSYIDLYLIQ 126
Query: 416 W---PIGLNADYS--HSDVDFMETWRGLEDAQRMGILKA 517
W P+ N D S + E WR LE+ +G++++
Sbjct: 127 WSFTPVLTNFDGSVAVNHRPIHEVWRELEECVELGMIRS 165
Score = 35.1 bits (77), Expect = 1.6
Identities = 19/50 (38%), Positives = 26/50 (52%)
Frame = +1
Query: 454 RRLHGDLARIGRCSANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEV 603
R +H + C G I+ IG++NFN Q + +L IKP QIEV
Sbjct: 145 RPIHEVWRELEECVELGMIRSIGVANFNCQMVLDLLSYAKIKPVVNQIEV 194
>UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293|Rep: Aldo/keto reductase of
diketogulonate reductase family - Leuconostoc
mesenteroides subsp. mesenteroides (strain ATCC 8293
/NCDO 523)
Length = 288
Score = 85.4 bits (202), Expect = 1e-15
Identities = 46/118 (38%), Positives = 64/118 (54%)
Frame = +2
Query: 74 MNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWR 253
+NNG MP +G G + + ++ + V+ AI+ G R DTA VY E +
Sbjct: 6 LNNGAQMPQLGFGVF---------QIPAEETKQAVVDAINAGYRSIDTARVYGNEAETGQ 56
Query: 254 TVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 427
V + VV RE++F+TTKLW ++ AI+DSLKKLG DY DL L+H P G
Sbjct: 57 GVNEAIANAVVAREELFLTTKLWLSEFSYEAAKGAIDDSLKKLGTDYADLILLHQPYG 114
>UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 292
Score = 85.4 bits (202), Expect = 1e-15
Identities = 56/153 (36%), Positives = 75/153 (49%)
Frame = +2
Query: 59 VPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETE 238
+P+ + G +P +G GTY K + D V RA++VG RH DTA +Y E
Sbjct: 16 IPTFMLPTGSPIPVLGFGTY---------KVAPEDTYDAVSRALEVGYRHIDTAQMYGNE 66
Query: 239 TRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 418
V +E + RED+FITTK+ N+ H A +I SL+ L DY+DL L+HW
Sbjct: 67 AE----VGAALEASGIAREDLFITTKVDNSNHEPDRAAASIRRSLEDLRTDYVDLLLVHW 122
Query: 419 PIGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
P L Y D W LEDA G +A
Sbjct: 123 P--LPTLYGG---DVALPWPALEDAFNAGGARA 150
Score = 34.3 bits (75), Expect = 2.9
Identities = 13/35 (37%), Positives = 22/35 (62%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G + IGLSN+ ++ +E V + T+ P +Q+E H
Sbjct: 146 GGARAIGLSNYEREHVEAVREVATVAPHVLQVESH 180
>UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1;
Propionibacterium freudenreichii subsp. shermanii|Rep:
Putative aldo-keto reductase - Propionibacterium
freudenreichii subsp. shermanii
Length = 280
Score = 85.0 bits (201), Expect = 2e-15
Identities = 53/156 (33%), Positives = 79/156 (50%)
Frame = +2
Query: 50 TMEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVY 229
T P+++++ G MP +G GT+ K ++ R V AI+ G R DTA Y
Sbjct: 5 TTPTPTVELSGGTRMPMLGMGTW---------PLKGEECRAAVASAIEQGYRLVDTAEAY 55
Query: 230 ETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 409
E V V E R +IF+TTK H R V +A+ SL++LGLDY+DL+L
Sbjct: 56 GNE----EAVGKAVREAGPDRAEIFVTTKFSKQWHSRKGVHEALEHSLERLGLDYVDLFL 111
Query: 410 MHWPIGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
MHWP+ Y ++ +RG+ + + G+ KA
Sbjct: 112 MHWPMPGEGSY-------VDAYRGMVELKEQGLAKA 140
>UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinomycetales|Rep: 2,5-didehydrogluconate reductase -
Kineococcus radiotolerans SRS30216
Length = 289
Score = 85.0 bits (201), Expect = 2e-15
Identities = 55/157 (35%), Positives = 86/157 (54%)
Frame = +2
Query: 47 STMEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASV 226
S M VP++ +N+GR++P +G GV + + V A+D+G RH DTA +
Sbjct: 8 SAMTVPTILLNDGREIPQLGF---------GVFQIEPGDTAQAVKTALDLGYRHIDTAQM 58
Query: 227 YETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLY 406
Y E V + + V R++I++T+KL N H +A++DS++KL IDLY
Sbjct: 59 YGNEAE----VAQGIADSGVPRDEIWVTSKLNNGFHEPDAARKAVDDSVEKL-RGPIDLY 113
Query: 407 LMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
L+HWP L Y DF+ TW+ LE+A+ G L++
Sbjct: 114 LIHWP--LPTLYGG---DFVSTWKVLEEARAAGKLRS 145
Score = 38.7 bits (86), Expect = 0.13
Identities = 17/37 (45%), Positives = 24/37 (64%)
Frame = +1
Query: 496 ANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
A G ++ IG+SNF L+R+ +E T+ P QIEVH
Sbjct: 139 AAGKLRSIGVSNFQVNHLQRLAQEATVVPAVNQIEVH 175
>UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Yersinia pestis
Length = 277
Score = 85.0 bits (201), Expect = 2e-15
Identities = 52/156 (33%), Positives = 86/156 (55%)
Frame = +2
Query: 50 TMEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVY 229
TM+ P +K+ +GR MP +G G + ++ ++ V +A++VG R DTA++Y
Sbjct: 2 TMQ-PLIKLYDGRLMPQLGLGVW---------QASIQETELAVSKALEVGYRSIDTAAIY 51
Query: 230 ETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 409
+ E + +K V R+++FITTKLWN + QA+ SL+KL LDY+DLYL
Sbjct: 52 KNEEGVGKALKA----AAVARDELFITTKLWNDDQHNPQ--QALETSLQKLQLDYVDLYL 105
Query: 410 MHWPIGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
+HWP + H ++ WR L + G++++
Sbjct: 106 IHWP---DPKQDH----YVSAWRELVTLKEQGLIRS 134
Score = 34.3 bits (75), Expect = 2.9
Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSKTFRKKW--WNFVSLKVL*SWAIL 675
G I+ IG+ NF+ L+R++ E I P QIE+H +++ WN SW+ L
Sbjct: 130 GLIRSIGVCNFHIPHLQRLIDETGIAPTVNQIELHPLLQQRQLHAWNATHHIATESWSPL 189
>UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=10; Trichomonas vaginalis|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 312
Score = 84.2 bits (199), Expect = 3e-15
Identities = 51/158 (32%), Positives = 82/158 (51%), Gaps = 16/158 (10%)
Frame = +2
Query: 89 DMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAID-VG*RHFDTASVYETETRNWRTVKM 265
++P +G GTYL D +L+ + AI+ G RH DTA Y + T+K
Sbjct: 2 EIPQLGFGTYLANDP--------AKLKAALHYAIEECGVRHIDTAFAYYNQNVIGETLKE 53
Query: 266 KVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA--- 436
+G +KRED+FITTKLW T HR+ V ++++L +L L Y+DL+L+H PI +
Sbjct: 54 IFAKGKIKREDMFITTKLWCTHHRKDLVEPELHENLAQLQLSYVDLFLIHQPIAFKSLPA 113
Query: 437 ------------DYSHSDVDFMETWRGLEDAQRMGILK 514
+ +D +ET+ +E+ Q+ G+ +
Sbjct: 114 KDGTMMPKDEKGKIQYEQIDILETYHAMEECQKKGLTR 151
Score = 35.9 bits (79), Expect = 0.94
Identities = 17/37 (45%), Positives = 23/37 (62%)
Frame = +1
Query: 490 CSANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIE 600
C G + IG+SNF+ +QLER+ IKP A Q+E
Sbjct: 144 CQKKGLTRHIGVSNFSIEQLERIWFNCEIKPYANQVE 180
>UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 285
Score = 83.8 bits (198), Expect = 4e-15
Identities = 55/151 (36%), Positives = 79/151 (52%), Gaps = 1/151 (0%)
Frame = +2
Query: 68 LKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAID-VG*RHFDTASVYETETR 244
+K+ NG MP IG G Y K++ + + +++AID G R DTA VY E
Sbjct: 4 IKLANGLHMPIIGLGVY---------KAEGENCENTIIKAIDDYGYRMIDTAQVYFNE-- 52
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
V +++ +KREDIFITTK+W + + +I+ SLKKL +YIDL L+H P
Sbjct: 53 --EFVGNAIKQTKIKREDIFITTKVWISNYGYNNTMYSISKSLKKLQTNYIDLVLLHQPF 110
Query: 425 GLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
G D+ W+ LE + GI+KA
Sbjct: 111 G----------DYYSAWKALEVLYKKGIVKA 131
>UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Acinetobacter sp. (strain ADP1)
Length = 297
Score = 83.8 bits (198), Expect = 4e-15
Identities = 52/153 (33%), Positives = 80/153 (52%)
Frame = +2
Query: 59 VPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETE 238
+P L +++G +PA+G GTY Q GV D ++RA+ G R D+A YE E
Sbjct: 22 IPDLILHDGHSIPALGFGTYTLKGQQGV---------DTMLRALGHGYRMLDSAFNYENE 72
Query: 239 TRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 418
V V + + R++IFIT+KL H + + I +SL ++ DY+DLYL+HW
Sbjct: 73 G----AVGAAVRQSGLLRDEIFITSKLPGRHHAYDKAMETIEESLYRMQFDYLDLYLIHW 128
Query: 419 PIGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
P Y +E W+ L DAQ+ G +++
Sbjct: 129 PNPQQGLY-------IEAWQALIDAQKKGYIRS 154
Score = 35.9 bits (79), Expect = 0.94
Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 4/88 (4%)
Frame = +1
Query: 355 SYKRFTEETRSGLYRSLFDAL----AHWIKCRL*SFGRRLHGDLARIGRCSANGYIKGIG 522
+Y + E LYR FD L HW + G + A I GYI+ IG
Sbjct: 101 AYDKAMETIEESLYRMQFDYLDLYLIHWPNPQQ---GLYIEAWQALID-AQKKGYIRSIG 156
Query: 523 LSNFNKQQLERVLKEGTIKPDAIQIEVH 606
+SNF + +E + +E + P Q+E+H
Sbjct: 157 VSNFLPKHIETLRRETGVIPVINQVELH 184
>UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA
- Apis mellifera
Length = 321
Score = 83.4 bits (197), Expect = 5e-15
Identities = 49/125 (39%), Positives = 72/125 (57%)
Frame = +2
Query: 53 MEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYE 232
ME ++ + NG MP IG GT+ ++++K+L D + A++ G RH DTA+ YE
Sbjct: 1 MEKNTILLPNGELMPIIGFGTW---------QAQEKELEDALNIALEAGYRHIDTATSYE 51
Query: 233 TETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 412
E +K + +KR DIFI TKL +R +V + I SL+ L L+Y+DLYL+
Sbjct: 52 NEKVIGDVLKNWFDSKKLKRSDIFIVTKLPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLI 111
Query: 413 HWPIG 427
H PIG
Sbjct: 112 HVPIG 116
Score = 40.3 bits (90), Expect = 0.044
Identities = 18/35 (51%), Positives = 24/35 (68%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G K IGLSNFN Q++R+LK +K +QIE+H
Sbjct: 155 GRTKAIGLSNFNISQIKRILKNTKMKISMLQIELH 189
>UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Escherichia coli (strain UTI89 / UPEC)
Length = 294
Score = 83.4 bits (197), Expect = 5e-15
Identities = 52/129 (40%), Positives = 69/129 (53%), Gaps = 2/129 (1%)
Frame = +2
Query: 137 GVVKSKDKQL-RDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKVEEGVVKREDIFITT 313
GV + DK + + V+ AI G R DTA+VY E V+ + EG+ RE++FIT+
Sbjct: 23 GVFQVTDKDVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGEAVREAISEGLCTREELFITS 82
Query: 314 KLWNTQHRRTEVAQA-INDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLED 490
KLW ++A A I SLKK GL+Y DLYL+H + D+ WR LED
Sbjct: 83 KLWVQDMLNQDIAAAGIEASLKKSGLEYFDLYLLHQAMR----------DYFSAWRALED 132
Query: 491 AQRMGILKA 517
A G LKA
Sbjct: 133 AYEEGKLKA 141
>UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=3; Lactobacillales|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 292
Score = 83.4 bits (197), Expect = 5e-15
Identities = 50/146 (34%), Positives = 72/146 (49%)
Frame = +2
Query: 80 NGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTV 259
+G +MP +G G + + G K V+ AI G R DTA+ Y E +
Sbjct: 8 SGIEMPLLGFGVFQ-VQEKGAAKQ-------AVLDAIKTGYRLIDTAASYGNEREVGEAI 59
Query: 260 KMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNAD 439
+ +G+VKRE++F+T+K+W + AI SL++L LDY+DLYL+H P
Sbjct: 60 LEAINQGIVKREELFVTSKMWVQDVSAQQATAAIQSSLQRLNLDYLDLYLIHQPYN---- 115
Query: 440 YSHSDVDFMETWRGLEDAQRMGILKA 517
D WR +E A R G LKA
Sbjct: 116 ------DVFGAWRAMESAYRSGQLKA 135
Score = 33.1 bits (72), Expect = 6.6
Identities = 18/43 (41%), Positives = 25/43 (58%)
Frame = +1
Query: 499 NGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSKTFRKK 627
+G +K IG+SNF+ QL + + IKP QIEV+ KK
Sbjct: 130 SGQLKAIGVSNFDIAQLTNLAEFSDIKPMLNQIEVNPFQQNKK 172
>UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep:
Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 287
Score = 82.6 bits (195), Expect = 8e-15
Identities = 55/157 (35%), Positives = 82/157 (52%), Gaps = 2/157 (1%)
Frame = +2
Query: 53 MEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYE 232
M VPS+++ +G MP +G GTY D +QL+ V A+ G R FDTA+VY
Sbjct: 1 MIVPSVRLMSGTQMPLLGLGTYKLQDH--------EQLKQSVSCALQAGYRAFDTAAVYG 52
Query: 233 TETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 412
E + +K + + + RED+FI +KL + H + SL++L +YIDLYL+
Sbjct: 53 NEAHLGQVLKELLPKYGLIREDVFIISKLAPSDH-GLRAKEGCLRSLEQLDCEYIDLYLI 111
Query: 413 HWP--IGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
HWP GL+ + S ++W LE+ G KA
Sbjct: 112 HWPGMEGLDPEDSRHSEYRAQSWATLEEFHASGQFKA 148
>UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep:
Aldehyde reductase - Acidobacteria bacterium (strain
Ellin345)
Length = 313
Score = 82.6 bits (195), Expect = 8e-15
Identities = 44/110 (40%), Positives = 59/110 (53%)
Frame = +2
Query: 92 MPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKV 271
+PA+G GT + + ++D A+ G RHFD A Y E ++
Sbjct: 20 IPALGFGTLIADPALTITATRD---------ALAAGFRHFDCAERYRNEREVGEALRAGR 70
Query: 272 EEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 421
G + RE+IF+TTKLWNT HR V A SL +LGLDY+DLYL+H P
Sbjct: 71 AAGNIAREEIFVTTKLWNTNHRPERVEPAFEASLDRLGLDYLDLYLIHTP 120
>UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1;
Clostridium beijerinckii NCIMB 8052|Rep:
2,5-didehydrogluconate reductase - Clostridium
beijerinckii NCIMB 8052
Length = 289
Score = 82.6 bits (195), Expect = 8e-15
Identities = 47/149 (31%), Positives = 77/149 (51%)
Frame = +2
Query: 68 LKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRN 247
+K NG +P +G G Y +K + V AI +G RHFDTA +Y E
Sbjct: 8 IKAVNGIKIPQVGFGVYK--------LNKGEDFETAVGEAIKIGYRHFDTAKIYGNE--- 56
Query: 248 WRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 427
+ + + +E+ + RE+ FIT+K+WNT H +A + KKL ++Y+D+YL+H+
Sbjct: 57 -KDLGLAIEKSQIPREEFFITSKVWNTDHGYEATKKAFEQTCKKLNVEYLDMYLIHFA-- 113
Query: 428 LNADYSHSDVDFMETWRGLEDAQRMGILK 514
+ Y ++ETW +E+ G +K
Sbjct: 114 --SSY------YLETWHAMEELYLQGKIK 134
Score = 35.1 bits (77), Expect = 1.6
Identities = 17/35 (48%), Positives = 21/35 (60%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G IK IG++NF Q LE ++K I P QIE H
Sbjct: 131 GKIKVIGVANFQIQHLEELMKHSRITPMINQIETH 165
>UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=3; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 309
Score = 82.6 bits (195), Expect = 8e-15
Identities = 50/155 (32%), Positives = 82/155 (52%), Gaps = 14/155 (9%)
Frame = +2
Query: 92 MPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAI-DVG*RHFDTASVYETETRNWRTVKMK 268
+P+IG GT+L D L+ V AI D G RH D A+ Y+ + +
Sbjct: 4 IPSIGLGTFLAEDPAA--------LKAAVHSAIEDSGYRHVDCAAYYKNQEIIGEALSEI 55
Query: 269 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA---- 436
+G VKRE+++IT+K+WNT+HR + + + +LK+L L+Y+DL L+HW +
Sbjct: 56 FAKGQVKREEVWITSKVWNTKHRPDLLVKDVKKTLKELKLEYLDLVLVHWACAFQSREDD 115
Query: 437 DYSHSD---------VDFMETWRGLEDAQRMGILK 514
+Y D +D +ETW+ +E+ +G+ K
Sbjct: 116 EYLPRDETGKIITENIDILETWKAMEECYNLGLAK 150
>UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 700
Score = 82.6 bits (195), Expect = 8e-15
Identities = 46/127 (36%), Positives = 66/127 (51%)
Frame = +2
Query: 44 ASTMEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTAS 223
+S + + NG +P +G GT+ K +Q V AI G RH D A
Sbjct: 4 SSVRRSANFTLANGAQIPKLGFGTW---------KMSKEQATPAVAHAIKTGYRHIDCAW 54
Query: 224 VYETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDL 403
Y RN V +++ V R +++T+KLWN+ H V +A++ SLK LG DY+DL
Sbjct: 55 AY----RNEDAVAAGIKKAGVPRSQLWLTSKLWNSFHHPEHVEKALDASLKDLGTDYLDL 110
Query: 404 YLMHWPI 424
YLMHWP+
Sbjct: 111 YLMHWPV 117
Score = 35.9 bits (79), Expect = 0.94
Identities = 16/46 (34%), Positives = 28/46 (60%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSKTFRKKWWNF 639
G ++ IG+SNFN ++ V+ E +IKP Q+EV+ ++ N+
Sbjct: 161 GKVRNIGVSNFNIRRTSEVVDEASIKPVVNQVEVNLGVHNEELRNY 206
>UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 301
Score = 82.6 bits (195), Expect = 8e-15
Identities = 47/116 (40%), Positives = 67/116 (57%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
S K+++G DMPA+G GT+L SK ++ + V A+ +G RH D A+ Y E
Sbjct: 6 SFKLSSGYDMPAVGLGTWL---------SKPHEVENAVETALRLGYRHIDAAACYLNENE 56
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 412
V ++ V R+ IFIT+KLWNT H V +A+N +LK L DY+DLYL+
Sbjct: 57 ----VGNGWKKSGVPRDQIFITSKLWNTHHHPDHVEEAVNKTLKDLQTDYLDLYLV 108
Score = 35.9 bits (79), Expect = 0.94
Identities = 19/64 (29%), Positives = 33/64 (51%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSKTFRKKWWNFVSLKVL*SWAILFR 681
G ++ IG+SNF +++E +LK I P QIE H + ++ KV ++ +
Sbjct: 172 GKVRSIGVSNFTIEKIEELLKTARIPPAVNQIEAHPYLQQPALHKYLKEKVTNILSVAYS 231
Query: 682 FLGS 693
LG+
Sbjct: 232 PLGN 235
>UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase B - Corynebacterium sp. (strain SHS752001)
Length = 277
Score = 82.6 bits (195), Expect = 8e-15
Identities = 52/153 (33%), Positives = 80/153 (52%)
Frame = +2
Query: 59 VPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETE 238
+P++ +N+GR G GTY GV ++ AID G R DTA YE E
Sbjct: 4 IPTISLNDGRPFAEPGLGTYNLRGDEGVA---------AMVAAIDSGYRLLDTAVNYENE 54
Query: 239 TRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 418
+ R V+ V R+++ + +K+ QH R E +I SL +LGLD IDL L+HW
Sbjct: 55 SEVGRAVRASS----VDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHW 110
Query: 419 PIGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
P + S +++TWRG+ DA+ G++++
Sbjct: 111 P-------NPSVGRWLDTWRGMIDAREAGLVRS 136
>UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Lactobacillus acidophilus
Length = 278
Score = 81.8 bits (193), Expect = 1e-14
Identities = 55/148 (37%), Positives = 75/148 (50%)
Frame = +2
Query: 74 MNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWR 253
+NNG MP +G G Y D Q + VV ++VG R DTA +Y E +
Sbjct: 7 LNNGIKMPRLGFGVYQIDDL--------AQAQQVVEDGLEVGYRLVDTAQIYGNE----Q 54
Query: 254 TVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 433
V ++ V REDIFIT+K+W + +A +DS+KKL LDYIDLYL+H P
Sbjct: 55 AVGDAIKHSNVPREDIFITSKIWVDDYGYDNTLKAFDDSMKKLQLDYIDLYLIHKPYN-- 112
Query: 434 ADYSHSDVDFMETWRGLEDAQRMGILKA 517
D+ TWR LE + G ++A
Sbjct: 113 --------DYYGTWRALERLYQEGRIRA 132
>UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3;
n=39; cellular organisms|Rep: NADPH-dependent aldose
reductase GRE3 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 327
Score = 81.8 bits (193), Expect = 1e-14
Identities = 43/117 (36%), Positives = 62/117 (52%)
Frame = +2
Query: 74 MNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWR 253
+NNG MP +G G + K K + + AI +G R FD A Y E
Sbjct: 7 LNNGLKMPLVGLGCW---------KIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGE 57
Query: 254 TVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
++ + EG+V R+DIF+ +KLWN H V A+ +L +GLDY+DLY +H+PI
Sbjct: 58 GIRKAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPI 114
Score = 37.5 bits (83), Expect = 0.31
Identities = 18/39 (46%), Positives = 24/39 (61%)
Frame = +1
Query: 490 CSANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
C G IK IG+SNF ++ +L+ IKP A+QIE H
Sbjct: 158 CVDEGLIKSIGVSNFQGSLIQDLLRGCRIKPVALQIEHH 196
>UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto
reductase family 1, member B10, partial; n=1; Macaca
mulatta|Rep: PREDICTED: similar to aldo-keto reductase
family 1, member B10, partial - Macaca mulatta
Length = 275
Score = 81.4 bits (192), Expect = 2e-14
Identities = 43/103 (41%), Positives = 59/103 (57%), Gaps = 6/103 (5%)
Frame = +2
Query: 146 KSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKVEEGVVKREDIFITTK--- 316
KS ++++ V AID G RH D A VY+ E ++ K++E VKRED+FI +K
Sbjct: 42 KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVSKVHM 101
Query: 317 ---LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA 436
LW T R V +A +LK L L Y+D+YL+HWP G A
Sbjct: 102 AHWLWTTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKA 144
Score = 33.5 bits (73), Expect = 5.0
Identities = 18/44 (40%), Positives = 27/44 (61%), Gaps = 2/44 (4%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHSKTFRKK 627
G +K +G+SNFN Q+E++L K G KP Q+E H ++K
Sbjct: 152 GLVKALGISNFNHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEK 195
>UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10;
Alphaproteobacteria|Rep: Aldo/keto reductase -
Mesorhizobium sp. (strain BNC1)
Length = 274
Score = 81.4 bits (192), Expect = 2e-14
Identities = 38/101 (37%), Positives = 62/101 (61%)
Frame = +2
Query: 119 LGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKVEEGVVKRED 298
LGF GV + D ++ ++ A++ G RHFDTA +Y+ E R + E +RED
Sbjct: 14 LGF---GVFRMSDAEVERIIPAALEAGFRHFDTAQIYQNEAALGRAL----ERAGARRED 66
Query: 299 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 421
+F+TTK+W + + A ++++SL+KL +D +DL L+HWP
Sbjct: 67 LFLTTKVWVDNYSADKFAASVDESLEKLKVDQVDLLLLHWP 107
>UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr1 scaffold_5, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 247
Score = 81.0 bits (191), Expect = 3e-14
Identities = 44/126 (34%), Positives = 70/126 (55%), Gaps = 10/126 (7%)
Frame = +2
Query: 170 DVVMRAIDVG*RHFDTASVYETETRNWRTVKMKVEEGVVK-REDIFITTKLWNTQHRRTE 346
D ++ AI++G RHFD + Y +E +K V+ G++K R+++FIT+KLW +
Sbjct: 36 DSILTAIELGYRHFDCVAAYLSEKPLGEAIKKAVKLGLIKSRDELFITSKLWCSDAHHDR 95
Query: 347 VAQAINDSLK---------KLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQR 499
V A+ ++LK L LDY+DLYL+HW G H +D W+ +ED Q+
Sbjct: 96 VLPALQNTLKISSILSFSKNLQLDYLDLYLIHWSDG------HLPIDLGSVWKAMEDFQK 149
Query: 500 MGILKA 517
+ + KA
Sbjct: 150 LSLTKA 155
>UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep:
Benzil reductase - Bacillus subtilis
Length = 276
Score = 80.6 bits (190), Expect = 3e-14
Identities = 51/151 (33%), Positives = 78/151 (51%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
++K++NG +MP G G + + N +S V AI G R DTA++Y+ E
Sbjct: 8 TVKLHNGVEMPWFGLGVFKVENGNEATES--------VKAAIKNGYRSIDTAAIYKNE-- 57
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
V + ++E V RE++FIT+K+WN A SL++L LDY+DLYL+HWP
Sbjct: 58 --EGVGIGIKESGVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWP- 114
Query: 425 GLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
+ +TWR LE + G ++A
Sbjct: 115 --------GKDKYKDTWRALEKLYKDGKIRA 137
Score = 40.7 bits (91), Expect = 0.033
Identities = 18/43 (41%), Positives = 27/43 (62%)
Frame = +1
Query: 499 NGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSKTFRKK 627
+G I+ IG+SNF LE +LK+ IKP Q+E H + +K+
Sbjct: 132 DGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQVEFHPRLTQKE 174
>UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus
djamor|Rep: Reductase AKOR2 - Pleurotus djamor
Length = 306
Score = 80.6 bits (190), Expect = 3e-14
Identities = 47/121 (38%), Positives = 71/121 (58%), Gaps = 1/121 (0%)
Frame = +2
Query: 62 PSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETET 241
P + +N G MPA+ G + G + + + Q ++ + A+ G RH DTA +Y TE
Sbjct: 5 PPIVLNTGARMPALALGGWAG-----LTEEERTQAKEWFLTALKSGYRHIDTAQIYYTE- 58
Query: 242 RNWRTVKMKVEEGVVKREDIFITTKL-WNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 418
++V + E + RE++FITTKL WN H R VA++ SL+ LG +YIDLYL+H+
Sbjct: 59 ---KSVGNAIRESGIPREELFITTKLPWN-HHSR--VAESFQKSLENLGTEYIDLYLVHF 112
Query: 419 P 421
P
Sbjct: 113 P 113
Score = 34.7 bits (76), Expect = 2.2
Identities = 14/35 (40%), Positives = 23/35 (65%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G +K IG+SN++ + LE +LK + P Q+E+H
Sbjct: 154 GKVKAIGVSNYSIKTLEELLKTAKVVPAVNQVELH 188
>UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 288
Score = 80.2 bits (189), Expect = 4e-14
Identities = 51/154 (33%), Positives = 78/154 (50%), Gaps = 2/154 (1%)
Frame = +2
Query: 62 PSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETET 241
PS+ +NN MP +G GT+ Q + D L+ G R FDTA+VY E
Sbjct: 6 PSVLLNNDIQMPLLGLGTFRLQGQEDTYSAVDAALK--------AGYRAFDTAAVYRNEA 57
Query: 242 RNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 421
++ + + + RED+FIT+KL + + ++ SL++LGL YIDLYL+HWP
Sbjct: 58 HLGHALRCLLPKHGLSREDVFITSKL-GPKDQGSKARNGCQKSLEQLGLGYIDLYLIHWP 116
Query: 422 --IGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
GL + + ++WR LE+ G +A
Sbjct: 117 GTQGLPVGDKRNPENRAQSWRVLEEFYSEGKFRA 150
Score = 33.9 bits (74), Expect = 3.8
Identities = 12/39 (30%), Positives = 23/39 (58%)
Frame = +1
Query: 496 ANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSK 612
+ G + IG+SN+ + ++ +LK + P +Q+E H K
Sbjct: 144 SEGKFRAIGVSNYTVEHMQELLKSCKVPPAVLQVEFHPK 182
>UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 274
Score = 80.2 bits (189), Expect = 4e-14
Identities = 47/149 (31%), Positives = 84/149 (56%), Gaps = 5/149 (3%)
Frame = +2
Query: 83 GRDMPAIGXGTYL--GFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVY---ETETRN 247
G ++PA+G GT+ GF+ S+D+++ +++ AI +G H DTA Y TE
Sbjct: 10 GEEIPALGLGTWGIGGFETPDY--SRDEEMVELLKTAIKMGYTHIDTAEYYGGGHTEELI 67
Query: 248 WRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 427
+ +K +RED+FI +K+W T RR ++ +++ ++LK+L DY+DLYL+HWP
Sbjct: 68 GKAIKD------FRREDLFIVSKVWPTHLRRDDLLRSLENTLKRLDTDYVDLYLIHWP-- 119
Query: 428 LNADYSHSDVDFMETWRGLEDAQRMGILK 514
+ ++ ET + + R G+++
Sbjct: 120 ------NPEIPLEETLSAMAEGVRQGLIR 142
>UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 268
Score = 80.2 bits (189), Expect = 4e-14
Identities = 50/139 (35%), Positives = 72/139 (51%)
Frame = +2
Query: 71 KMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNW 250
+++NG +P +G GTYL + SKD + + A+D G RH D A +Y E
Sbjct: 5 QLSNGVTIPMLGFGTYL-------IDSKD--VPAAIKTALDAGYRHLDCAHIYGNEP--- 52
Query: 251 RTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 430
V ++ + R D+FIT+K+WN + A + +L L LDY+DLYL+HWP
Sbjct: 53 -AVGEAIKASGIDRSDLFITSKVWNADQGYDKTLAAFDQTLSDLQLDYLDLYLIHWP--- 108
Query: 431 NADYSHSDVDFMETWRGLE 487
N D +D TWR LE
Sbjct: 109 NEDDFELTLD---TWRVLE 124
Score = 36.3 bits (80), Expect = 0.71
Identities = 15/33 (45%), Positives = 24/33 (72%)
Frame = +1
Query: 508 IKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
++ IG+SNF++ QL++V + T+KP QIE H
Sbjct: 132 VRAIGVSNFSEDQLKQVFEMATVKPMINQIERH 164
>UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC
1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase);
n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid
4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid
5-beta-reductase) - Homo sapiens (Human)
Length = 326
Score = 80.2 bits (189), Expect = 4e-14
Identities = 51/162 (31%), Positives = 77/162 (47%), Gaps = 12/162 (7%)
Frame = +2
Query: 68 LKMNNGRDMPAIGXGTYLGFDQNGVVKSKDK-QLRDVVMRAIDVG*RHFDTASVYETETR 244
+ +++G +P IG GTY KS K V AID G RH D A +Y+ E
Sbjct: 10 IPLSDGNSIPIIGLGTY------SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHE 63
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
++ K+ EG V+REDIF KLW T H V + +L+ L LDY+DLY++ P+
Sbjct: 64 VGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPM 123
Query: 425 GL-----------NADYSHSDVDFMETWRGLEDAQRMGILKA 517
N + + + TW +E + G++K+
Sbjct: 124 AFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKS 165
Score = 37.9 bits (84), Expect = 0.23
Identities = 17/41 (41%), Positives = 27/41 (65%), Gaps = 2/41 (4%)
Frame = +1
Query: 490 CSANGYIKGIGLSNFNKQQLERVLKEGTI--KPDAIQIEVH 606
C G +K +G+SNFN++QLE +L + + KP + Q+E H
Sbjct: 157 CKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECH 197
>UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA15457-PA - Nasonia vitripennis
Length = 388
Score = 79.4 bits (187), Expect = 8e-14
Identities = 46/124 (37%), Positives = 72/124 (58%)
Frame = +2
Query: 59 VPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETE 238
V LK+++G ++PA+G GT +K + + + + A++ G RH DTA Y+ E
Sbjct: 23 VEKLKLSSGHEIPAVGLGT-------STIKLDE--MDNAISSALENGYRHIDTAFSYDNE 73
Query: 239 TRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 418
+ +K ++G KREDIFIT+KL + +R V + SLK LGLDY+D+YL+H
Sbjct: 74 AAIGKILKKWFDKGG-KREDIFITSKLPSQGNRPQSVETYLKRSLKDLGLDYVDMYLIHT 132
Query: 419 PIGL 430
P +
Sbjct: 133 PFAV 136
Score = 39.9 bits (89), Expect = 0.058
Identities = 18/46 (39%), Positives = 26/46 (56%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSKTFRKKWWNF 639
G K IGLSNFN+ Q+ + IKP +Q+E H+ +K+ F
Sbjct: 173 GRAKSIGLSNFNQSQVLNIYNNAEIKPSNLQVETHAYLQQKQLRKF 218
>UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 295
Score = 79.4 bits (187), Expect = 8e-14
Identities = 47/146 (32%), Positives = 79/146 (54%), Gaps = 1/146 (0%)
Frame = +2
Query: 80 NGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTV 259
NG +P G GTY V SK++ + + A+D+G RH DTA +YE E + +
Sbjct: 12 NGSKLPVFGLGTYK-------VVSKEEMVT-FLRTALDLGYRHIDTAIMYENEKQIGDAL 63
Query: 260 KMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNAD 439
+ +EG KRED+F+ TKL++ ++ T+V + SL+ L +YIDLYL+H+ D
Sbjct: 64 QEIYKEGKYKREDLFLVTKLFS--NKNTKVEDQVRQSLQNLQTNYIDLYLLHYASSPPTD 121
Query: 440 -YSHSDVDFMETWRGLEDAQRMGILK 514
+ + + W E+ + G+++
Sbjct: 122 QFELTHKPVFQVWAEFEELVQKGLIR 147
>UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase
family protein; n=3; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 299
Score = 79.4 bits (187), Expect = 8e-14
Identities = 51/161 (31%), Positives = 86/161 (53%), Gaps = 5/161 (3%)
Frame = +2
Query: 47 STMEVPS-LKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTAS 223
S+ E+ + ++NG+ MPA G G+ V+S + ++ +++ +A+DVG RH DTA
Sbjct: 2 SSQEIQKVITLSNGQKMPAFGLGS-------SRVQSVE-EVTNLIRKALDVGYRHIDTAQ 53
Query: 224 VYETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDL 403
+YE E +K EG KREDIF+ TK + + + + L+KL +DY+DL
Sbjct: 54 MYENEQFIGAALKTIFGEGKYKREDIFLVTK--QASIKGVSCLEIMKEQLQKLQVDYVDL 111
Query: 404 YLMHWPIGLNAD----YSHSDVDFMETWRGLEDAQRMGILK 514
L+H P+ +D ++H V + W E+ +G+ K
Sbjct: 112 LLIHVPLAAPSDDYQQWNHKPVH--QIWAEFEEIHSLGLAK 150
Score = 34.3 bits (75), Expect = 2.9
Identities = 17/35 (48%), Positives = 22/35 (62%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G KG+G+SNFN Q + +L IKP QIE+H
Sbjct: 147 GLAKGLGVSNFNCQMIIDLLAYCKIKPLVNQIELH 181
>UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 263
Score = 79.4 bits (187), Expect = 8e-14
Identities = 42/97 (43%), Positives = 57/97 (58%), Gaps = 1/97 (1%)
Frame = +2
Query: 137 GVVKSKDK-QLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKVEEGVVKREDIFITT 313
G+ K+ D + D + A+ G R DTAS Y+ E V + + V R+D+FITT
Sbjct: 7 GLYKTTDAVEAEDAIAAAVQNGYRLLDTASAYKNE----EFVGCGIAKCGVPRKDLFITT 62
Query: 314 KLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
K+WN R +V A SL +LGLDYIDLYL+HWP+
Sbjct: 63 KIWNNAQRLGDVEGAFQRSLDRLGLDYIDLYLIHWPV 99
>UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 284
Score = 79.0 bits (186), Expect = 1e-13
Identities = 45/119 (37%), Positives = 67/119 (56%), Gaps = 2/119 (1%)
Frame = +2
Query: 56 EVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYET 235
+ P +K+NNG +MP +G GT+L + GV + + AID G RH DTA Y+
Sbjct: 4 KAPMVKLNNGLEMPVLGLGTWLSKEGEGV---------EAIKAAIDAGYRHIDTAYFYQN 54
Query: 236 ETRNWRTVKMKVEEGVVKREDIFITTKL--WNTQHRRTEVAQAINDSLKKLGLDYIDLY 406
E ++ K+EEGVV RED+F+TTK W+T++ A + L+ +DYID +
Sbjct: 55 EKEVGEAIRAKIEEGVVCREDLFVTTKFIDWDTKNLMPYDA---DGKLQFSDVDYIDTW 110
Score = 40.7 bits (91), Expect = 0.033
Identities = 19/46 (41%), Positives = 28/46 (60%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSKTFRKKWWNF 639
G +K IG+SNFN +Q+ R+L E IKP Q+E + ++K F
Sbjct: 120 GKVKSIGVSNFNSEQITRLLAECEIKPVTNQVECNPSLNQRKLTEF 165
>UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 -
Trichoderma atroviride (Hypocrea atroviridis)
Length = 327
Score = 79.0 bits (186), Expect = 1e-13
Identities = 55/172 (31%), Positives = 82/172 (47%), Gaps = 16/172 (9%)
Frame = +2
Query: 50 TMEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVY 229
T+ + +N G +PA+G GT+ G + V +A+DVG RH D A Y
Sbjct: 9 TLSSTTYTLNTGAKIPAVGFGTFANEGAKGETYA-------AVTKALDVGYRHLDCAWFY 61
Query: 230 ETETRNWRTVK-MKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLY 406
E ++ V R+D+FI TK+WN H +V + +S + L +DYIDL+
Sbjct: 62 LNEDEVGDAIRDFLARRPDVTRKDLFICTKVWNHLHEPEDVKWSAKNSCENLKVDYIDLF 121
Query: 407 LMHWPIGL--NADYS---HSDVDFM----------ETWRGLEDAQRMGILKA 517
L+HWPI NAD + D ++ TWR +E+ GI+KA
Sbjct: 122 LVHWPIAAEKNADRTVKIGPDGKYVINKALTENPEPTWRAMEELVDSGIVKA 173
Score = 33.9 bits (74), Expect = 3.8
Identities = 15/36 (41%), Positives = 24/36 (66%)
Frame = +1
Query: 499 NGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
+G +K IG+SN+ L+++L+ IKP QIE+H
Sbjct: 168 SGIVKAIGVSNWTIPGLKQLLEFARIKPAVNQIEIH 203
>UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 302
Score = 79.0 bits (186), Expect = 1e-13
Identities = 53/156 (33%), Positives = 86/156 (55%), Gaps = 1/156 (0%)
Frame = +2
Query: 53 MEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYE 232
M VP +K++NG ++PAIG G+ + + K ++++L D V+ AI+ G H DTA Y
Sbjct: 1 MTVPKVKLSNGLEIPAIGFGSGTKWKRPPGEK-EERELIDAVVSAINAGHLHIDTAEFYG 59
Query: 233 TETRNWRTVKMKVEEGVVKREDIFITTK-LWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 409
TE + + ++E V R+DIF+T+K L+ + ++I++ LK L DY DL+L
Sbjct: 60 TE----KQIGEAIKESGVPRKDIFLTSKTLFGL--LADDPIESISNQLKTLQTDYFDLFL 113
Query: 410 MHWPIGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
+H P + +Y D + W LE G+ KA
Sbjct: 114 IHVPPNDDINY-----DLAKAWGVLEQLYEKGLAKA 144
Score = 35.5 bits (78), Expect = 1.2
Identities = 16/35 (45%), Positives = 21/35 (60%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G K IG+SN + +LE ++K IKP QIE H
Sbjct: 140 GLAKAIGVSNHSPAELETIIKVAKIKPHVNQIEFH 174
>UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose
reductase - Hordeum vulgare (Barley)
Length = 320
Score = 78.6 bits (185), Expect = 1e-13
Identities = 49/155 (31%), Positives = 78/155 (50%), Gaps = 8/155 (5%)
Frame = +2
Query: 74 MNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWR 253
+ +G MPA+G GT+ ++ V + G RH DTA+ Y E +
Sbjct: 18 LKSGHAMPAVGLGTW---------RAGSDTAHSVRTAITEAGYRHVDTAAEYGVEKEVGK 68
Query: 254 TVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 433
+K +E G+ R+D+F+T+K+W T V A+ ++LK L LDYIDLY +HWP L
Sbjct: 69 GLKAAMEAGI-DRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLK 127
Query: 434 ADYSHS--------DVDFMETWRGLEDAQRMGILK 514
D +H + D W+ +E+ + G++K
Sbjct: 128 -DGAHMPPEAGEVLEFDMEGVWKEMENLVKDGLVK 161
>UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
CG2767-PA - Nasonia vitripennis
Length = 356
Score = 78.2 bits (184), Expect = 2e-13
Identities = 55/165 (33%), Positives = 85/165 (51%), Gaps = 14/165 (8%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
++K+++G DMP IG GT+ + + + V A++ G RH DTA Y E
Sbjct: 27 TIKLSSGHDMPMIGLGTW---------QMPPEAIEVAVTAALESGYRHIDTAFTYGNEEA 77
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
+T+K ++G KRED+FITTKL R V + SL+KLGL+Y+++YL+H P
Sbjct: 78 IGKTLKKWFDKGG-KREDLFITTKLPPIGMRAEYVESYLKLSLEKLGLEYVNMYLIHKPF 136
Query: 425 -----------GLNADYS---HSDVDFMETWRGLEDAQRMGILKA 517
LN D S +D D + WR +E + G +++
Sbjct: 137 AFVKDKYKYEPALNPDGSVVLDTDTDHVAIWRAMEKQVKAGRVRS 181
Score = 40.7 bits (91), Expect = 0.033
Identities = 18/36 (50%), Positives = 24/36 (66%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHS 609
G ++ IGLSNFNK QL V + IKP +QIE+ +
Sbjct: 177 GRVRSIGLSNFNKSQLLNVYEHAEIKPSNLQIELQA 212
>UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3;
Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis
alexandrii HTCC2633
Length = 275
Score = 78.2 bits (184), Expect = 2e-13
Identities = 42/115 (36%), Positives = 63/115 (54%)
Frame = +2
Query: 80 NGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTV 259
NG D+P +G GT+ + +D+ V A+ G RH DTA +Y E V
Sbjct: 8 NGADIPKLGFGTW---------QLEDEDAARGVATALKTGYRHIDTAQIYGNEA----AV 54
Query: 260 KMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
++ VKRED F+TTK+W + R ++ ++ +SL KL DY+DL L+HWP+
Sbjct: 55 GDGWKQSGVKREDFFLTTKVWRDKFRDGDLQASVKESLDKLKTDYVDLLLLHWPV 109
>UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;
Corynebacterineae|Rep: 2,5-didehydrogluconate reductase
- Mycobacterium sp. (strain KMS)
Length = 283
Score = 78.2 bits (184), Expect = 2e-13
Identities = 49/153 (32%), Positives = 78/153 (50%)
Frame = +2
Query: 59 VPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETE 238
+PS+ +N+G +P +G G V + + + V A++ G R DTA+VY E
Sbjct: 11 IPSVSLNDGHSIPVLGLG---------VGELSEAEAERSVAAALEAGYRLIDTAAVYGNE 61
Query: 239 TRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 418
V V + RE+I++TTKL A SL++LGLDY+DLYL+HW
Sbjct: 62 A----AVGRAVNASGIPREEIYVTTKLAVADQGFGTSQDAARASLERLGLDYVDLYLIHW 117
Query: 419 PIGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
P G + Y +++W GL A++ G+ ++
Sbjct: 118 PAGDHGKY-------IDSWGGLMKAKQDGVARS 143
>UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 272
Score = 77.8 bits (183), Expect = 2e-13
Identities = 49/145 (33%), Positives = 76/145 (52%)
Frame = +2
Query: 80 NGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTV 259
NG +PAIG GT+ + + VV +A+ +G RH DTA VY+ E R V
Sbjct: 7 NGARIPAIGLGTW---------ELSGRPCARVVEQALRLGYRHIDTAQVYDNE----REV 53
Query: 260 KMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNAD 439
V V+R+D+F+TTK+W ++ +++ +SL +L L +DL L+HWP
Sbjct: 54 GDGVRASGVRRDDVFLTTKVWTNHFAPNDLERSVKESLARLRLPSVDLLLLHWP------ 107
Query: 440 YSHSDVDFMETWRGLEDAQRMGILK 514
+S V ET L A++MG+ +
Sbjct: 108 --NSHVPLAETLGALSHARQMGLTR 130
>UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2;
Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 281
Score = 77.8 bits (183), Expect = 2e-13
Identities = 47/143 (32%), Positives = 74/143 (51%)
Frame = +2
Query: 59 VPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETE 238
+P L +NNG +P +G G + + ++ + +V A++ G RH DTA+ Y
Sbjct: 9 IPQLTLNNGVKIPQLGFGVF---------QVPPEETQRIVEDALEAGYRHIDTAAAY--- 56
Query: 239 TRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 418
RN V + + REDIFITTKL N + +A +S K LG++++DLYL+HW
Sbjct: 57 -RNEAGVGAAISASGIPREDIFITTKLRNGEQGNAH--EAFQNSRKALGVEFVDLYLIHW 113
Query: 419 PIGLNADYSHSDVDFMETWRGLE 487
P+ Y+ E W+ +E
Sbjct: 114 PVPSQGLYT-------EAWKAME 129
Score = 34.3 bits (75), Expect = 2.9
Identities = 16/44 (36%), Positives = 27/44 (61%)
Frame = +1
Query: 496 ANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSKTFRKK 627
AN I+ IG+SNF + L+ +L + P Q+E+H TF+++
Sbjct: 133 ANSQIRAIGVSNFLGEHLDTLLPAADVVPAVNQVEIH-PTFQQQ 175
>UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8;
Saccharomycetales|Rep: Probable oxidoreductase YJR096W -
Saccharomyces cerevisiae (Baker's yeast)
Length = 282
Score = 77.8 bits (183), Expect = 2e-13
Identities = 53/152 (34%), Positives = 80/152 (52%), Gaps = 3/152 (1%)
Frame = +2
Query: 71 KMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVY--ETETR 244
K++NG +P+I GTY + +S Q ++V + G RHFDTA +Y E E
Sbjct: 7 KLSNGFKIPSIALGTY------DIPRS---QTAEIVYEGVKCGYRHFDTAVLYGNEKEVG 57
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKL-GLDYIDLYLMHWP 421
+ + + G KRE+IF TTKLWN+Q+ AI L ++ GL YIDL L+H P
Sbjct: 58 DGIIKWLNEDPGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSP 117
Query: 422 IGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
+ +ETWR +++A G++K+
Sbjct: 118 L-------EGSKLRLETWRAMQEAVDEGLVKS 142
>UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep:
Oxidoreductase - Xanthomonas campestris pv. campestris
(strain 8004)
Length = 267
Score = 77.4 bits (182), Expect = 3e-13
Identities = 42/127 (33%), Positives = 67/127 (52%)
Frame = +2
Query: 137 GVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKVEEGVVKREDIFITTK 316
G + KD+ + D V A+ +G R DTA +Y+ E + V + + V R+ +F+TTK
Sbjct: 9 GTFRLKDQVVIDSVRNALALGYRAIDTAQIYDNEAQ----VGQAIADAGVPRDQLFVTTK 64
Query: 317 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 496
+W + R + ++ +SL+KLG DY+DL L+HWP V E L DA+
Sbjct: 65 IWVDRFSRDTLQPSLQESLRKLGTDYVDLTLIHWP------SPKDQVPMREYLEALADAK 118
Query: 497 RMGILKA 517
G+ +A
Sbjct: 119 AQGLTRA 125
>UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;
n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
hypothetical protein - Ornithorhynchus anatinus
Length = 419
Score = 77.0 bits (181), Expect = 4e-13
Identities = 48/147 (32%), Positives = 76/147 (51%), Gaps = 1/147 (0%)
Frame = +2
Query: 53 MEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAI-DVG*RHFDTASVY 229
+ VP++ + NG ++P +G GT D V+ A+ + G RH DTA Y
Sbjct: 10 LPVPTVPLANGLNIPILGLGT----------SHVGGYSHDAVIYALKECGIRHIDTAKRY 59
Query: 230 ETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 409
E + ++E VKRE+++ITTKLW T + Q+ +S +LG++Y+DL+L
Sbjct: 60 GCEL----LLGKAIQESGVKREELWITTKLWLTDYGYESAKQSCLESCNRLGVEYLDLFL 115
Query: 410 MHWPIGLNADYSHSDVDFMETWRGLED 490
+HWP S + ETWR +E+
Sbjct: 116 IHWPDAQLPGKSSREAR-AETWRAMEE 141
>UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4;
Bifidobacterium|Rep: Dehydrogenase or reductase protein
- Bifidobacterium longum
Length = 289
Score = 77.0 bits (181), Expect = 4e-13
Identities = 43/121 (35%), Positives = 64/121 (52%)
Frame = +2
Query: 59 VPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETE 238
VP + + +G +P +G G L D GVV VV A++ G RH D A+ Y E
Sbjct: 11 VPDIALKDGHSIPQVGLGV-LRIDDEGVVP--------VVESALEAGYRHIDGAAGYNNE 61
Query: 239 TRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 418
R + KRE +++TTKL ++Q +A ++SLK L LDY+D+Y++HW
Sbjct: 62 AGVGRALAASGYNKGAKRETLWVTTKLRDSQQGYDSALKAFDNSLKLLQLDYVDMYMIHW 121
Query: 419 P 421
P
Sbjct: 122 P 122
>UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
2,5-diketo-D-gluconic acid reductase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 159
Score = 77.0 bits (181), Expect = 4e-13
Identities = 42/121 (34%), Positives = 66/121 (54%)
Frame = +2
Query: 59 VPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETE 238
VP++ +NNG +MP +G G + + + + V A++ G R DTA+ Y E
Sbjct: 4 VPTVTLNNGVEMPQLGYGVF---------QVPEDETAAAVGAALEAGYRSIDTAAAYGNE 54
Query: 239 TRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 418
R + G+ R+++F+TTKLWN +A + SL+ LGLD++DLYL+HW
Sbjct: 55 AAVGRAL---AGSGLA-RDELFVTTKLWNADQGYDNALRAFDTSLELLGLDHLDLYLIHW 110
Query: 419 P 421
P
Sbjct: 111 P 111
>UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae
str. PEST
Length = 310
Score = 77.0 bits (181), Expect = 4e-13
Identities = 43/117 (36%), Positives = 64/117 (54%), Gaps = 1/117 (0%)
Frame = +2
Query: 92 MPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKV 271
+P IG GTY +G ++ + AIDVG R FDTA Y E ++ K+
Sbjct: 17 LPTIGLGTYSILGADG---------KEAIRTAIDVGYRMFDTAVAYGNEAIVGEAIREKI 67
Query: 272 EE-GVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNAD 439
E + R+D FI +KL + HR+ V + +L +LG+DY+DLYLMH P+ L ++
Sbjct: 68 RECNNLTRDDFFIISKLSGSYHRQDLVEKCCRMTLDRLGMDYVDLYLMHTPVALQSE 124
Score = 35.9 bits (79), Expect = 0.94
Identities = 15/38 (39%), Positives = 23/38 (60%)
Frame = +1
Query: 487 RCSANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIE 600
+C G + IG+SNFN+ Q+ +L + +I P QIE
Sbjct: 152 QCYQEGLCRSIGVSNFNEHQINALLSDASIVPAVNQIE 189
>UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 303
Score = 77.0 bits (181), Expect = 4e-13
Identities = 51/150 (34%), Positives = 73/150 (48%)
Frame = +2
Query: 68 LKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRN 247
LKM++G +P G G Y + DK+ D V A++ G RH DTA YE E
Sbjct: 33 LKMHDGNAIPQFGLGVY---------EMNDKETYDCVKWALEAGYRHVDTAEWYENEAPC 83
Query: 248 WRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 427
+ + ++ RE+IF+T+KL N + SLK+ G++Y DLYLMH IG
Sbjct: 84 GKAIADFLKATGTSREEIFLTSKLKNNSSYEQAFVD-LKGSLKRSGVEYFDLYLMHSAIG 142
Query: 428 LNADYSHSDVDFMETWRGLEDAQRMGILKA 517
V W+ L DAQ G++K+
Sbjct: 143 -------GPVIRKNVWKALCDAQSQGLVKS 165
>UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2;
Schizosaccharomyces pombe|Rep: Probable oxidoreductase
C26F1.07 - Schizosaccharomyces pombe (Fission yeast)
Length = 321
Score = 77.0 bits (181), Expect = 4e-13
Identities = 41/115 (35%), Positives = 64/115 (55%)
Frame = +2
Query: 80 NGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTV 259
+G +P +G GT+ +S+ Q ++ V A+ G RH D A++Y E V
Sbjct: 20 DGSKIPGLGLGTW---------RSEPNQTKNAVKTALQYGYRHIDAAAIYGNEDE----V 66
Query: 260 KMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
++E V R+DI++T+KLW H V +A+ +LK L LDY+D YL+HWP+
Sbjct: 67 GDGIKESGVPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPV 121
Score = 41.9 bits (94), Expect = 0.014
Identities = 18/35 (51%), Positives = 24/35 (68%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G ++ IGLSNFN LER+LK +KP Q+E+H
Sbjct: 159 GKVRHIGLSNFNDTNLERILKVAKVKPAVHQMELH 193
>UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep:
Lin2739 protein - Listeria innocua
Length = 283
Score = 76.6 bits (180), Expect = 5e-13
Identities = 52/151 (34%), Positives = 71/151 (47%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
++K+NNG ++P +G GTY D + V AI G RH DTA Y E
Sbjct: 3 TVKLNNGIEVPILGFGTYQITDAG--------EAEQAVKEAIAAGYRHIDTAQSYMNE-- 52
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
V + V R+++FITTK+W V + + SLK+LGLDYIDL L+H P
Sbjct: 53 --EAVGRGIAASGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYIDLLLIHQPY 110
Query: 425 GLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
D W +E+ Q G +KA
Sbjct: 111 N----------DVYGAWMAMEELQAQGKIKA 131
>UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Oceanobacillus iheyensis
Length = 280
Score = 76.6 bits (180), Expect = 5e-13
Identities = 50/154 (32%), Positives = 77/154 (50%)
Frame = +2
Query: 56 EVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYET 235
++P++ +++G +P +G GTY +GV + AID G R DTA YE
Sbjct: 4 QIPNVTLHDGLTIPKVGFGTYRLNGNDGV---------QAINNAIDHGYRLIDTAYNYEN 54
Query: 236 ETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 415
E TV V RE + IT+KL H + I +SL + LDY DLYL+H
Sbjct: 55 EG----TVGEAVRRSSTPREQLLITSKLPGRYHHYDKAVTTIQESLYRANLDYYDLYLIH 110
Query: 416 WPIGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
WP + D+ ++E W+ L +A+R G +++
Sbjct: 111 WPNPI------QDI-YVEAWQALIEAKRRGYIRS 137
Score = 34.7 bits (76), Expect = 2.2
Identities = 18/46 (39%), Positives = 28/46 (60%), Gaps = 3/46 (6%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH---SKTFRKKW 630
GYI+ IG+ NF + LER+ +E P QIE+H ++ ++KW
Sbjct: 133 GYIRSIGVCNFLPEHLERLKQETGELPTINQIELHPFFNQEDQRKW 178
>UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 301
Score = 76.6 bits (180), Expect = 5e-13
Identities = 47/123 (38%), Positives = 67/123 (54%)
Frame = +2
Query: 56 EVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYET 235
+VP++K+NNG +MP +G GT+L D + V AI VG R DTA Y
Sbjct: 28 KVPTVKLNNGMEMPQLGVGTFLVKDNAA----------ERVCHAIKVGFRLIDTAQGYGN 77
Query: 236 ETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 415
E + V + + R ++FITTK+ + R V Q+++ SL LG DYIDL L+H
Sbjct: 78 E----KEVGEGICRSGIDRRELFITTKVNTMEMRGGTVRQSLDKSLADLGTDYIDLVLIH 133
Query: 416 WPI 424
WP+
Sbjct: 134 WPV 136
Score = 34.3 bits (75), Expect = 2.9
Identities = 15/34 (44%), Positives = 22/34 (64%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEV 603
G I+ IG+SNFN L+ +L+ I+P QIE+
Sbjct: 154 GKIRSIGVSNFNPHHLDELLEYARIRPVVNQIEI 187
>UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1;
Parvularcula bermudensis HTCC2503|Rep: Putative
uncharacterized protein - Parvularcula bermudensis
HTCC2503
Length = 278
Score = 76.6 bits (180), Expect = 5e-13
Identities = 36/102 (35%), Positives = 64/102 (62%)
Frame = +2
Query: 119 LGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKVEEGVVKRED 298
LGF G + + + R AI+ G RH D A++Y+ E + V +++ + R++
Sbjct: 14 LGF---GTWQLEGEDARTSTRTAIETGYRHIDGAAIYKNEKK----VGEGIKDSGIPRDE 66
Query: 299 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
+F+TTK+WN ++ ++A+++SL +LGLDY++L L+HWPI
Sbjct: 67 LFVTTKIWNEDIQKGRHSEAVDESLDRLGLDYVNLILLHWPI 108
>UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1;
Griffithsia japonica|Rep: Mannose 6-phosphate reductase
- Griffithsia japonica (Red alga)
Length = 174
Score = 76.6 bits (180), Expect = 5e-13
Identities = 46/131 (35%), Positives = 68/131 (51%)
Frame = +2
Query: 53 MEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYE 232
M + + +G MP G GT+ K+ ++ V A+ G RH D A+VY
Sbjct: 1 MSTNTATLQSGAKMPLNGFGTW---------KASVEETEQAVTAALRAGYRHIDCAAVYW 51
Query: 233 TETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 412
E + + GVVKRED+FIT+K+WNT H +V + SLK +DY DL+L+
Sbjct: 52 NEAAVGTAISKAISGGVVKREDLFITSKVWNTCHATDKVVDSCRQSLKDHQVDYFDLFLV 111
Query: 413 HWPIGLNADYS 445
IG+ ++YS
Sbjct: 112 R-DIGV-SNYS 120
>UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto
reductase family - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 279
Score = 76.2 bits (179), Expect = 7e-13
Identities = 42/110 (38%), Positives = 64/110 (58%)
Frame = +2
Query: 92 MPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKV 271
MPA+G GT+ +NG +V +A+++G RH DTA +Y E R V +
Sbjct: 15 MPALGFGTWQL--ENGTAVP-------LVEKALEIGYRHIDTAQIYGNE----RDVGAAI 61
Query: 272 EEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 421
VKR++IF+TTK+W Q ++ ++ SL+KLG+D +DL L+HWP
Sbjct: 62 RNSGVKRDEIFLTTKVWIDQFADGDLQRSAEKSLEKLGVDQVDLLLLHWP 111
>UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 305
Score = 76.2 bits (179), Expect = 7e-13
Identities = 44/125 (35%), Positives = 67/125 (53%), Gaps = 8/125 (6%)
Frame = +2
Query: 137 GVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKV--EEGV----VKRED 298
G+ K + +++ ++ G R DTAS+Y E R + + V +G+ +KRED
Sbjct: 31 GIGTFKLNDIENIIKVGLENGYRRIDTASMYNNEERIGKVLNEMVTKNDGLDGKKIKRED 90
Query: 299 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP--IGLNADYSHSDVDFMET 472
+FIT+K + +A SLKKL LDY+D YL+HWP GL+ S + + +T
Sbjct: 91 LFITSKCSFMEQGYENALKAFESSLKKLQLDYLDCYLIHWPGVKGLDGSDSGNSIQRAQT 150
Query: 473 WRGLE 487
WR LE
Sbjct: 151 WRALE 155
>UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5;
Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas
putida
Length = 296
Score = 76.2 bits (179), Expect = 7e-13
Identities = 42/120 (35%), Positives = 63/120 (52%)
Frame = +2
Query: 62 PSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETET 241
P + +NNG MPA+G G + + ++ + AI G R DTA Y E
Sbjct: 6 PLINLNNGVKMPALGLGVFA---------ASAEETASAIASAISSGYRLIDTARSYNNEA 56
Query: 242 RNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 421
+ V + V R ++F+TTKL+N + +A ++SL +LGLDY+DLYL+HWP
Sbjct: 57 Q----VGEGIRNSGVDRAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLHWP 112
>UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinobacteria (class)|Rep: 2,5-didehydrogluconate
reductase - Arthrobacter sp. (strain FB24)
Length = 276
Score = 75.8 bits (178), Expect = 1e-12
Identities = 49/152 (32%), Positives = 77/152 (50%)
Frame = +2
Query: 62 PSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETET 241
P +++N+G +P IG GT+ D Q+ V+ A++ G RH DTA Y E
Sbjct: 5 PVIELNDGHRIPQIGLGTW---------PLDDHQVAAAVVNAVEGGYRHIDTAVKYGNE- 54
Query: 242 RNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 421
+ V + + R ++FITTKL + ++ SLK+LGLDY+DL L+HWP
Sbjct: 55 ---KGVGNGIRSSGLDRSELFITTKLDGEFQGQDRAVAGLDGSLKRLGLDYVDLLLIHWP 111
Query: 422 IGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
+ D +F+ TW+ E Q G +++
Sbjct: 112 L------PRRD-EFISTWKTFERLQADGKVRS 136
Score = 33.1 bits (72), Expect = 6.6
Identities = 15/39 (38%), Positives = 23/39 (58%)
Frame = +1
Query: 487 RCSANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEV 603
R A+G ++ IG+SNF LER++ + P QI+V
Sbjct: 127 RLQADGKVRSIGVSNFKPAHLERLMAACDVVPAVNQIQV 165
>UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:
ENSANGP00000029046 - Anopheles gambiae str. PEST
Length = 331
Score = 75.8 bits (178), Expect = 1e-12
Identities = 46/120 (38%), Positives = 63/120 (52%), Gaps = 1/120 (0%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
+ K+N G D+P G GTY Q + + D A++ G RH DTA VY E
Sbjct: 33 TFKLNTGFDIPLAGFGTYQIHGQELIYQVLDY--------ALEAGYRHIDTAVVYRNEEY 84
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHR-RTEVAQAINDSLKKLGLDYIDLYLMHWP 421
+K + + +KREDIFIT+KL + + V Q + SL L DY+DLYL+HWP
Sbjct: 85 IGTALKTLLPKYNLKREDIFITSKLISQSGKDEAFVEQMVRKSLANLQTDYLDLYLIHWP 144
>UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=4; Oligohymenophorea|Rep: Oxidoreductase,
aldo/keto reductase family protein - Tetrahymena
thermophila SB210
Length = 297
Score = 75.8 bits (178), Expect = 1e-12
Identities = 49/158 (31%), Positives = 81/158 (51%), Gaps = 4/158 (2%)
Frame = +2
Query: 53 MEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYE 232
++VP L G +P IG GTY QN + V A+ +G H DTASVY
Sbjct: 11 VKVPILNFREGGSIPQIGYGTY-ELRQNDCIIG--------VTEALKIGYTHIDTASVYR 61
Query: 233 TETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 412
E + + +KRED+FIT+K+ + + +A+ D L +L + Y+D L+
Sbjct: 62 NEQDIAKVIHNPAYG--IKREDLFITSKISPGEQGYEQAKKAVQDMLTRLNIKYLDCVLI 119
Query: 413 HWPIGLNA----DYSHSDVDFMETWRGLEDAQRMGILK 514
HWP G++ D ++ + +ETW+ L + ++ G++K
Sbjct: 120 HWP-GVSKLPPNDPKNAQIR-LETWKALIELRKAGVIK 155
Score = 42.7 bits (96), Expect = 0.008
Identities = 19/46 (41%), Positives = 27/46 (58%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSKTFRKKWWNF 639
G IK IG+SNFN L+ ++++ KP+ Q E+H F KK F
Sbjct: 152 GVIKHIGVSNFNINHLQHLIEKSEFKPEMNQFEIHPLCFNKKTIEF 197
>UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 274
Score = 75.8 bits (178), Expect = 1e-12
Identities = 42/113 (37%), Positives = 61/113 (53%)
Frame = +2
Query: 83 GRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVK 262
G +PA+G GT+ + + R+ V A+ +G RH DTA Y E R V
Sbjct: 8 GTSVPALGLGTW---------QLTGQSCRETVETALGMGYRHIDTAQAYGNE----RQVG 54
Query: 263 MKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 421
+ ++ V RED+F+TTKL + V ++ +SL KLG DY+DL L+HWP
Sbjct: 55 LGMDAAAVDREDVFLTTKLDGSNRDERSVRRSTRESLNKLGTDYLDLLLIHWP 107
>UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=5; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus brevis (strain ATCC 367 / JCM 1170)
Length = 282
Score = 75.4 bits (177), Expect = 1e-12
Identities = 50/149 (33%), Positives = 76/149 (51%)
Frame = +2
Query: 71 KMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNW 250
K+ +GR MP +G GTYL DQ + + A D G R FDTA +Y RN
Sbjct: 11 KLADGRQMPVMGFGTYLLNDQ--------PTMNTAIQTAWDAGYRMFDTAMLY----RNE 58
Query: 251 RTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 430
+ +++ + RE +F+T+K+ + +A+ SLK+L DY+DL L+HWP+
Sbjct: 59 DILGPAIQQLGLPREGLFLTSKVAEIVQGYDQTMKAVEGSLKRLQTDYLDLLLIHWPV-- 116
Query: 431 NADYSHSDVDFMETWRGLEDAQRMGILKA 517
H F +TWR LE + G +K+
Sbjct: 117 ---REH----FFDTWRALEQLKADGQVKS 138
>UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 278
Score = 75.4 bits (177), Expect = 1e-12
Identities = 50/152 (32%), Positives = 77/152 (50%)
Frame = +2
Query: 62 PSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETET 241
P++ + NG +MP +G GT+ D + V AI+ G R DTA Y+ ET
Sbjct: 8 PTVTLANGVEMPQLGLGTW---------PMTDDEAAKAVATAIETGYRLIDTAENYKNET 58
Query: 242 RNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 421
V + + V R+++F+TTK+ H +A SL++LGLDYIDL+L+HWP
Sbjct: 59 G----VGQGIRDAGVARDEVFLTTKMNKQWHSVDGARRACEASLERLGLDYIDLFLIHWP 114
Query: 422 IGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
N D ++E + GL G+++A
Sbjct: 115 ---NPDQG----TYVEAFEGLTRLLDAGLVRA 139
>UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Arthrobacter sp. (strain FB24)
Length = 291
Score = 75.4 bits (177), Expect = 1e-12
Identities = 51/165 (30%), Positives = 77/165 (46%), Gaps = 13/165 (7%)
Frame = +2
Query: 62 PSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETET 241
P L +NNG + +G G Y K +V A++ G RHFDTA++Y ET
Sbjct: 5 PRLSLNNGVLIDQLGFGLY---------KVPPADAAGLVTMALEAGYRHFDTAAMYGNET 55
Query: 242 RNWRTVKMKVE-----------EGV--VKREDIFITTKLWNTQHRRTEVAQAINDSLKKL 382
+ + E + RED+F+TTK+WN H +A + S+ L
Sbjct: 56 GVGKAIGALAGFAGGGPAGGSGEAAPSLSREDLFVTTKVWNDDHGYDATMRAFDTSMSNL 115
Query: 383 GLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
G++Y+DLYL+HWP F E++R +E R G ++A
Sbjct: 116 GMEYVDLYLIHWPCARRG-------LFTESYRAMETLYREGRIRA 153
Score = 33.9 bits (74), Expect = 3.8
Identities = 15/35 (42%), Positives = 21/35 (60%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G I+ IG+SNF LE +L+ + P QIE+H
Sbjct: 149 GRIRAIGVSNFQPAHLEHLLETAEVVPAVNQIELH 183
>UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus
terreus NIH2624|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 292
Score = 75.4 bits (177), Expect = 1e-12
Identities = 48/151 (31%), Positives = 79/151 (52%)
Frame = +2
Query: 53 MEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYE 232
M+ P+L + +G +P +G GT + ++ + +L +V+ A++ G H D A Y
Sbjct: 1 MKWPALSLKDGNLVPILGFGTGTAWYKDDPNDPTNPELIEVLKAALEKGFHHIDAADSYG 60
Query: 233 TETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 412
TE R V + + E + RE +FITTK+ +V A++ SL++L LDY+DLYL+
Sbjct: 61 TE----REVGIAIRESGIPREQLFITTKVLEGWK---DVPGALDASLERLQLDYVDLYLL 113
Query: 413 HWPIGLNADYSHSDVDFMETWRGLEDAQRMG 505
H P + + D W+GLE + G
Sbjct: 114 HNPYVI-----PNLTDIQSAWKGLEAVKATG 139
Score = 33.1 bits (72), Expect = 6.6
Identities = 14/37 (37%), Positives = 22/37 (59%)
Frame = +1
Query: 496 ANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
A G + IG+SNF + LE +L+ ++ P Q+E H
Sbjct: 137 ATGKARSIGVSNFQRNHLEAILETCSVVPAINQLEYH 173
>UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=1; Rhodobacterales bacterium HTCC2150|Rep:
2,5-diketo-D-gluconic acid reductase A - Rhodobacterales
bacterium HTCC2150
Length = 334
Score = 74.9 bits (176), Expect = 2e-12
Identities = 50/159 (31%), Positives = 76/159 (47%), Gaps = 7/159 (4%)
Frame = +2
Query: 50 TMEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVY 229
T + +N +PA+G GTYL + + D + + AI G RH DTAS Y
Sbjct: 34 TNTATTFTLNTTTTIPAVGFGTYL-------ISNDDA--KSTISAAIQAGYRHIDTASGY 84
Query: 230 ETETRNWRTVKMKVEEGVVKREDIFITTKLW-------NTQHRRTEVAQAINDSLKKLGL 388
+ E +K ++ + R+D+F+T KLW + + + + SL +LGL
Sbjct: 85 QNEKTVGAGIKAGLQSAGITRKDLFVTAKLWPGNPAWGDAPKTKAQTLDECDASLARLGL 144
Query: 389 DYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMG 505
DY+DLYL+H P G D+ +E WR L + Q G
Sbjct: 145 DYVDLYLIHAPYG-------GDMR-LEQWRALLELQANG 175
Score = 40.3 bits (90), Expect = 0.044
Identities = 18/37 (48%), Positives = 23/37 (62%)
Frame = +1
Query: 496 ANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
ANG + IG+SNFN+ L + G PDA QIE+H
Sbjct: 173 ANGKARSIGVSNFNESHLNEIKAAGLPMPDANQIELH 209
>UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=9; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 308
Score = 74.9 bits (176), Expect = 2e-12
Identities = 52/157 (33%), Positives = 79/157 (50%), Gaps = 16/157 (10%)
Frame = +2
Query: 92 MPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAI-DVG*RHFDTASVYETETRNWRTVKMK 268
+P IG GT+ + + L + + AI + G H D A YE E + ++
Sbjct: 4 IPTIGLGTWKS--------PRSEDLVNAITYAIKEAGYVHIDCALCYENEDIVGQALQQC 55
Query: 269 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI-----GLN 433
+ G+ KRE+I+IT+KLWNT HR V +A +LK L LDY+DLYLMH+P G+
Sbjct: 56 WDSGI-KRENIWITSKLWNTHHRLEIVEEACRKTLKDLRLDYLDLYLMHYPFAFQNTGIG 114
Query: 434 ADYSHSD----------VDFMETWRGLEDAQRMGILK 514
+ D V ++TW+ +E G++K
Sbjct: 115 GSLNPLDEKGNTIFDDGVSLIDTWKAMEKLVEKGLVK 151
>UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyces
cerevisiae YDR368w YPR1; n=1; Kluyveromyces lactis|Rep:
Similarities with sp|Q12458 Saccharomyces cerevisiae
YDR368w YPR1 - Kluyveromyces lactis (Yeast) (Candida
sphaerica)
Length = 127
Score = 74.9 bits (176), Expect = 2e-12
Identities = 32/62 (51%), Positives = 46/62 (74%)
Frame = +2
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
N V + + + RE+IF+TTKLWNTQ R + A A+N+SL++LGLDY+DL+L+HWP+
Sbjct: 4 NETAVGKGIRDSGIPREEIFVTTKLWNTQQR--DPASALNESLERLGLDYVDLFLIHWPV 61
Query: 425 GL 430
L
Sbjct: 62 PL 63
>UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus
niger|Rep: Putative frameshift - Aspergillus niger
Length = 357
Score = 74.9 bits (176), Expect = 2e-12
Identities = 51/159 (32%), Positives = 77/159 (48%), Gaps = 11/159 (6%)
Frame = +2
Query: 74 MNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWR 253
+N G +PA+G GT+ + D Q + V + + G R DTA VY E + R
Sbjct: 40 LNTGAKIPALGVGTF---------QDPDSQ-EETVCQVLQRGMRLIDTARVYGVEQQVGR 89
Query: 254 TVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 433
+K + V RE+IF+ TKLW +V +A++DSL+ L Y+DL LMH+P
Sbjct: 90 GIK----KSGVPREEIFLGTKLWCNDFHPDDVERAVDDSLRDLYTPYVDLLLMHYPCTFK 145
Query: 434 ADYS-----------HSDVDFMETWRGLEDAQRMGILKA 517
H + F++TWR LE + G ++A
Sbjct: 146 RGEDRFPRDAEGRMIHGETTFVDTWRALEKVVKTGKVRA 184
Score = 38.7 bits (86), Expect = 0.13
Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 6/58 (10%)
Frame = +1
Query: 451 GRRLHGDLARIGRCSA------NGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
GR +HG+ + A G ++ IG+SNF+K ++E +L+E + P Q+EVH
Sbjct: 157 GRMIHGETTFVDTWRALEKVVKTGKVRAIGVSNFSKGEIETLLRETSTVPAVHQMEVH 214
>UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde
reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep:
NADH/NADPH dependent indole-3-acetaldehyde reductase
AKR3C2 - Schizosaccharomyces pombe (Fission yeast)
Length = 284
Score = 74.5 bits (175), Expect = 2e-12
Identities = 47/140 (33%), Positives = 73/140 (52%)
Frame = +2
Query: 92 MPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKV 271
+PA G GT L + G + ++ + D V A+ G H D A VY E V + +
Sbjct: 12 VPAYGVGTALFKKEKGEI---NRTIVDSVKNALAAGFIHIDCAEVYGNEEE----VGVAL 64
Query: 272 EEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHS 451
+E V R +FIT+K+ H + +A+N+SL+KLG DY+DLYL+H PI +
Sbjct: 65 KEANVPRSKLFITSKV---MHNVDNIPEALNESLRKLGTDYLDLYLLHSPI----PFYEK 117
Query: 452 DVDFMETWRGLEDAQRMGIL 511
+ E W+ +E A G++
Sbjct: 118 KIPISEGWKAMETALGTGLV 137
Score = 37.5 bits (83), Expect = 0.31
Identities = 16/40 (40%), Positives = 23/40 (57%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSKTFR 621
G + +G+SNF LE +LK TI P QIE H + ++
Sbjct: 135 GLVHSVGVSNFRIPDLEELLKTSTITPRVNQIEFHPQVYK 174
>UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2;
Lactobacillus reuteri|Rep: 2,5-didehydrogluconate
reductase - Lactobacillus reuteri F275
Length = 300
Score = 74.1 bits (174), Expect = 3e-12
Identities = 50/153 (32%), Positives = 77/153 (50%), Gaps = 1/153 (0%)
Frame = +2
Query: 62 PSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETET 241
P +K+NNG +P +G G + K+ + D V+ DTA Y E
Sbjct: 11 PKIKLNNGHLIPQLGLGVWKASLAETQQMVKEAIMNDYVL---------IDTAKQYGNEA 61
Query: 242 RNWRTVKMKVEEGVVKREDIFITTKLWN-TQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 418
+ ++ + KR+ IF+TTK++N Q ++ QA+N+ LKKL +Y+DL L+HW
Sbjct: 62 AVGQGIQDGFKATGRKRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLLLHW 121
Query: 419 PIGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
P+ N Y+ E+WR LED + G KA
Sbjct: 122 PV--NDKYN-------ESWRALEDIYKDGQAKA 145
>UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5;
Trypanosomatidae|Rep: Aldo-keto reductase-like protein -
Leishmania major strain Friedlin
Length = 372
Score = 74.1 bits (174), Expect = 3e-12
Identities = 39/119 (32%), Positives = 56/119 (47%)
Frame = +2
Query: 68 LKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRN 247
+ M + +P +G GTY + + D V A+ G RH D A Y E
Sbjct: 22 IAMRDSHTIPQLGFGTY---------RLPVSEATDAVAFALSCGYRHVDCAKAYGNEAAV 72
Query: 248 WRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
+ + +RED+F+T+KLW T V A +L L LDY+DLYL+HWP+
Sbjct: 73 GEALAQALRTRCTRREDLFVTSKLWPTDQHPDHVEAACRATLAALQLDYLDLYLIHWPV 131
>UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase
family; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 307
Score = 73.7 bits (173), Expect = 4e-12
Identities = 51/157 (32%), Positives = 82/157 (52%), Gaps = 9/157 (5%)
Frame = +2
Query: 74 MNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWR 253
+NNG+ MPAIG GT+L + ++ V A++ G R D A Y+ E
Sbjct: 8 LNNGKFMPAIGLGTWL---------AAPGEVGKAVTLALENGYRLIDCARFYKNEKE--- 55
Query: 254 TVKMKVEEGVVK--REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 427
+M +E + RE++F+T+KLW Q T + ++ +S++ L Y+DLYL+HWPI
Sbjct: 56 IGEMGIEPFLKNHPREELFVTSKLWMDQV--TRIRESCLESIQDLKCKYLDLYLIHWPIA 113
Query: 428 LNADYSHS-------DVDFMETWRGLEDAQRMGILKA 517
L D S+ D+D E W+ +E G++K+
Sbjct: 114 LKVDASNPPKPEDFLDMDITEIWQEMERLVDEGLVKS 150
Score = 36.7 bits (81), Expect = 0.54
Identities = 16/35 (45%), Positives = 24/35 (68%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G +K IGLSNF Q+E+++K IKP Q+E++
Sbjct: 146 GLVKSIGLSNFTIPQIEKIMKMCRIKPVINQVELN 180
>UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep:
Aldo-keto reductase - Helicobacter hepaticus
Length = 292
Score = 73.7 bits (173), Expect = 4e-12
Identities = 55/152 (36%), Positives = 80/152 (52%), Gaps = 4/152 (2%)
Frame = +2
Query: 74 MNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWR 253
+NNG +P +G GT+ D N VV++ V A VG RH DTA Y E R
Sbjct: 17 LNNGNKIPKLGLGTWR-IDDN-VVEA-------AVREAFKVGYRHIDTAQAYGNE----R 63
Query: 254 TVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 433
V V + +KRE++FIT+K+ + +I+ SLK + LD+IDL L+H P N
Sbjct: 64 GVGEAVRKSKIKREELFITSKIRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSPQPWN 123
Query: 434 A----DYSHSDVDFMETWRGLEDAQRMGILKA 517
+ DY +V E + LEDAQ+ G +++
Sbjct: 124 SFRKGDYFKENV---EVYNALEDAQKAGKVRS 152
Score = 34.3 bits (75), Expect = 2.9
Identities = 16/35 (45%), Positives = 22/35 (62%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G ++ IG+SNF ++ LE +LK KP A QI H
Sbjct: 148 GKVRSIGVSNFLQKDLENILKNCKTKPAANQILCH 182
>UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase
oxidoreductase protein; n=1; Spiroplasma citri|Rep:
Putative aldo/keto reductase oxidoreductase protein -
Spiroplasma citri
Length = 138
Score = 73.7 bits (173), Expect = 4e-12
Identities = 41/115 (35%), Positives = 66/115 (57%)
Frame = +2
Query: 68 LKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRN 247
LK+ NG ++P IG GTY D++ V ++ ++ A+ G RH DTA +Y E
Sbjct: 8 LKLFNGVEIPLIGLGTYKMTDEHEVYQA--------IITALQNGYRHIDTAQIYGNEELI 59
Query: 248 WRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 412
+ +K + V R++IF+T+K+WN H+ Q I++ LK+L DY+DL L+
Sbjct: 60 GKAIK----DSGVPRKEIFLTSKIWNANHKYDAALQEIDNILKRLDTDYLDLCLV 110
>UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 289
Score = 73.3 bits (172), Expect = 5e-12
Identities = 43/126 (34%), Positives = 67/126 (53%)
Frame = +2
Query: 50 TMEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVY 229
T V + +NNG +P+IG G + + ++ D V +AI +G R DTA Y
Sbjct: 3 TSNVKLITLNNGNKIPSIGFGVF---------QIPKEETADCVKKAISIGYRLIDTAQAY 53
Query: 230 ETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 409
E +K+ VKRE+IF+TTK+W + + R +++ +SLK+L Y+DL L
Sbjct: 54 HNEKETGLGIKLSG----VKREEIFLTTKVWVSNYER--CYESVIESLKRLDTSYLDLIL 107
Query: 410 MHWPIG 427
+H P G
Sbjct: 108 LHQPFG 113
>UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15;
Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B -
Bradyrhizobium sp. (strain ORS278)
Length = 273
Score = 73.3 bits (172), Expect = 5e-12
Identities = 44/118 (37%), Positives = 62/118 (52%), Gaps = 1/118 (0%)
Frame = +2
Query: 83 GRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVK 262
G +P +G GT F G V RD V A+ +G RH DTA +Y E +
Sbjct: 8 GVRLPKLGLGT---FRMQGTV------CRDAVESALALGYRHIDTAEMYANED----AIG 54
Query: 263 MKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP-IGLN 433
+ + RED+ +TTK+W + +A + SLKKL LD++DLYL+HWP G+N
Sbjct: 55 AALAAAQIAREDLHVTTKVWPENLAPDAIRRAFDTSLKKLRLDFVDLYLIHWPATGMN 112
>UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3;
Saccharomycetales|Rep: Conjugated polyketone reductase
C1 - Candida parapsilosis (Yeast)
Length = 304
Score = 73.3 bits (172), Expect = 5e-12
Identities = 49/155 (31%), Positives = 80/155 (51%), Gaps = 7/155 (4%)
Frame = +2
Query: 71 KMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNW 250
K++NG +PA+ GT + + G DKQL + A+ G RH D A +Y T
Sbjct: 9 KLSNGNKIPAVAFGTGTKYFKRGH-NDLDKQLIGTLELALRSGFRHIDGAEIYGTN---- 63
Query: 251 RTVKMKVEEGVVKREDIFITTKLWNTQH-------RRTEVAQAINDSLKKLGLDYIDLYL 409
+ + + ++ + R+D+FIT K + H + A+ L+ LGL+Y+DLYL
Sbjct: 64 KEIGIALKNVGLNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLGLEYVDLYL 123
Query: 410 MHWPIGLNADYSHSDVDFMETWRGLEDAQRMGILK 514
+H+P ++ SH D +E WR LE A+ G+ +
Sbjct: 124 IHFP--YISEKSHG-FDLVEAWRYLERAKNEGLAR 155
>UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep:
Lmo2592 protein - Listeria monocytogenes
Length = 283
Score = 72.9 bits (171), Expect = 7e-12
Identities = 50/151 (33%), Positives = 71/151 (47%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
++K+NNG ++P +G GTY D + V AI G RH DTA Y E
Sbjct: 3 TVKLNNGVEVPILGFGTYQITDA--------AEAEHAVKDAIKAGYRHIDTAQSYMNE-- 52
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
V + V R+++FITTK+W V + + SLK+LGLDY+DL L+H P
Sbjct: 53 --EAVGRGIAASGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYVDLLLIHQPF 110
Query: 425 GLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
D W +E+ Q G ++A
Sbjct: 111 N----------DVYGAWIAMEELQASGKIRA 131
>UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=2; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
Length = 273
Score = 72.9 bits (171), Expect = 7e-12
Identities = 49/150 (32%), Positives = 75/150 (50%)
Frame = +2
Query: 68 LKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRN 247
L +NN +P G GTY + Q + V+ A + G R DTA Y+ E +
Sbjct: 4 LTLNNDVKIPIFGFGTY---------EISPDQTKQAVLSAFEEGYRLIDTAQYYQNEQQV 54
Query: 248 WRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 427
VK + R+++FITTK + T++ +++SL+++GLDY DL L+HWP+G
Sbjct: 55 GEAVKASG----LNRDEVFITTKTMTDGYEDTKIG--LDESLRRIGLDYFDLVLIHWPMG 108
Query: 428 LNADYSHSDVDFMETWRGLEDAQRMGILKA 517
D+D TW LE A + G +A
Sbjct: 109 -------HDID---TWHALEAAYKAGKTRA 128
Score = 34.3 bits (75), Expect = 2.9
Identities = 15/43 (34%), Positives = 26/43 (60%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSKTFRKKW 630
G + IG+SNFN +Q ++ + +++P QIE H F ++W
Sbjct: 124 GKTRAIGISNFNSRQTLDLIHQSSVRPMVDQIETH--LFLQQW 164
>UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=10;
Pezizomycotina|Rep: Related to aldo-keto reductase YPR1
- Neurospora crassa
Length = 322
Score = 72.9 bits (171), Expect = 7e-12
Identities = 45/154 (29%), Positives = 77/154 (50%), Gaps = 1/154 (0%)
Frame = +2
Query: 59 VPSLKMNNGRDMPAIGXGTYLGFDQNG-VVKSKDKQLRDVVMRAIDVG*RHFDTASVYET 235
+PSLK+++G ++P +G G ++G + + + + + A++ G H D A VY
Sbjct: 24 IPSLKLSDGNEIPMLGYGLGTANYKSGDSADTISEPIVNATLTALNAGYAHLDGAEVYGN 83
Query: 236 ETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 415
E R + + + R ++ITTK V Q+ N SL+KLGLDY+DLYL+H
Sbjct: 84 EVELGRAIA----QSKLPRSSLYITTK--TIVRAGDTVTQSFNRSLEKLGLDYVDLYLLH 137
Query: 416 WPIGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
P ++ + WR +E + G+ K+
Sbjct: 138 SPF-----FAKNPEQLQAAWREMEKIKDSGMAKS 166
>UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=91; Proteobacteria|Rep: 2,5-diketo-D-gluconic acid
reductase B - Yersinia pestis
Length = 267
Score = 72.9 bits (171), Expect = 7e-12
Identities = 33/95 (34%), Positives = 58/95 (61%)
Frame = +2
Query: 137 GVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKVEEGVVKREDIFITTK 316
G + +D+ + D V +A+ +G R DTA +YE E V ++E + R+++FITTK
Sbjct: 9 GTFRLQDQIVIDSVSQALTLGYRAIDTAQIYENEA----PVGQAIQESGINRDELFITTK 64
Query: 317 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 421
+W + ++ ++ +S++KL DY+DL L+HWP
Sbjct: 65 IWIANLSKDKLIPSLRESIQKLKTDYVDLTLIHWP 99
>UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep:
Lin2349 protein - Listeria innocua
Length = 294
Score = 72.5 bits (170), Expect = 9e-12
Identities = 38/97 (39%), Positives = 58/97 (59%), Gaps = 1/97 (1%)
Frame = +2
Query: 137 GVVKSKDKQ-LRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKVEEGVVKREDIFITT 313
GV + +++ + V +AI+VG R FDTA+VY E V + + V RE++FI++
Sbjct: 23 GVFQVTEQEFIAGAVEKAIEVGYRLFDTAAVYNNEA----IVGQAILDSAVPREELFISS 78
Query: 314 KLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
K+WN E A +L+ L LDY+DLYL+HWP+
Sbjct: 79 KVWNGDLGYDETLFAFERTLRNLKLDYLDLYLIHWPV 115
>UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis
vadensis ATCC BAA-548|Rep: Aldo/keto reductase -
Victivallis vadensis ATCC BAA-548
Length = 287
Score = 72.5 bits (170), Expect = 9e-12
Identities = 49/154 (31%), Positives = 76/154 (49%), Gaps = 1/154 (0%)
Frame = +2
Query: 56 EVPSLKMNNGRDMPAIGXGTY-LGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYE 232
+VP + NG +P +G GT+ +G + D + + R I G H DTA +Y
Sbjct: 3 DVPWKSLKNGFAIPVLGQGTWRMGGVDTPDTANDDADIA-AIRRGIATGLCHIDTAEMYA 61
Query: 233 TETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 412
V + ++ ++R D F+T K+W T R +V +A SLK+LG DYIDLYL+
Sbjct: 62 GGHAE-ELVGIAMKGQGIRRADYFLTDKVWKTHLRYDDVLRAAEASLKRLGTDYIDLYLI 120
Query: 413 HWPIGLNADYSHSDVDFMETWRGLEDAQRMGILK 514
H + DV ET R + +R G+++
Sbjct: 121 H--------QVNPDVPEEETIRAMNRLKREGVIR 146
>UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr1 scaffold_22, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 360
Score = 72.5 bits (170), Expect = 9e-12
Identities = 41/116 (35%), Positives = 62/116 (53%)
Frame = +2
Query: 74 MNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWR 253
+N +PAIG GT+ +S + V RA+ G R D A +Y E
Sbjct: 14 LNTKAKIPAIGLGTW---------QSGGDLCVEAVKRALSEGYRQIDCAHLYGNEVEVGE 64
Query: 254 TVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 421
+ + G +KRED+F+T+KL+ T + ++ ++ SLK LG+ Y+DLYLMHWP
Sbjct: 65 ALA-EAFNGSLKREDVFLTSKLYCTMNSLNKIENSVRVSLKNLGVTYLDLYLMHWP 119
Score = 34.7 bits (76), Expect = 2.2
Identities = 14/35 (40%), Positives = 23/35 (65%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G ++ IG+SNF QQ++ +LK I P Q+++H
Sbjct: 159 GLVRAIGVSNFGVQQIKELLKFAKIVPAVNQVKLH 193
>UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia
ATCC 50803
Length = 303
Score = 72.5 bits (170), Expect = 9e-12
Identities = 44/126 (34%), Positives = 66/126 (52%), Gaps = 6/126 (4%)
Frame = +2
Query: 95 PAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKVE 274
P +G GTYL D + + A+ +G RHFD A Y E K
Sbjct: 6 PCVGFGTYLVEDP------------EAIRSAVKLGYRHFDCAYRYGNERMIGEVFKEIFN 53
Query: 275 EGV--VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL----NA 436
+ VKRED++I +KLW H +VA I+++L+ L L+Y+D++LMHWP+ + +
Sbjct: 54 DDSYGVKREDLWIVSKLWPNFHEPEKVAYQISETLRDLQLEYLDVFLMHWPLAIKHLADR 113
Query: 437 DYSHSD 454
DY+ SD
Sbjct: 114 DYASSD 119
>UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Opitutaceae bacterium TAV2
Length = 334
Score = 72.1 bits (169), Expect = 1e-11
Identities = 42/154 (27%), Positives = 79/154 (51%), Gaps = 1/154 (0%)
Frame = +2
Query: 59 VPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETE 238
+P+L +++G +P +G G + D V + A + G R DTA +Y E
Sbjct: 59 IPTLPLSDGTSIPQLGLGVWQMPDDGAGVP---------IQAAFNAGYRAIDTAPIYGNE 109
Query: 239 TRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 418
R ++ + R++++ITTK+WN+ +A+ +SL +L L+Y+DLYL+HW
Sbjct: 110 EGVGRAIRASG----LPRKELYITTKVWNSAQGYDSTLRAVRESLGRLQLEYVDLYLIHW 165
Query: 419 PIGLNADYSHSDVD-FMETWRGLEDAQRMGILKA 517
P+ +D +++TW+ L + G+ ++
Sbjct: 166 PV--------PKIDRYVDTWKALAKIKADGLARS 191
Score = 34.3 bits (75), Expect = 2.9
Identities = 15/44 (34%), Positives = 25/44 (56%)
Frame = +1
Query: 481 IGRCSANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSK 612
+ + A+G + IG+SNF L+R+ E I P Q+E+H +
Sbjct: 180 LAKIKADGLARSIGVSNFTPVYLQRLFDETGIVPVVNQVELHPR 223
>UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9;
Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 316
Score = 72.1 bits (169), Expect = 1e-11
Identities = 40/118 (33%), Positives = 65/118 (55%)
Frame = +2
Query: 68 LKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRN 247
+ NG MPA+G GT+ ++ D+++ + A++ G RH DTA VY E
Sbjct: 7 ITFENGTTMPALGFGTW---------RASDEEVEKALNEALEAGYRHIDTAPVYLNEKTI 57
Query: 248 WRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 421
+ +K ++ G V R+++FI TKL R + V + + +SL L L+Y+DLY +H P
Sbjct: 58 GKVLKEWMDAGKVTRDELFIVTKLPPHGTRASTVEKFLKNSLDDLQLEYVDLYHVHVP 115
Score = 41.5 bits (93), Expect = 0.019
Identities = 18/35 (51%), Positives = 25/35 (71%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G + IGLSNFN++Q++R+L IKP +QIE H
Sbjct: 154 GLARNIGLSNFNQRQIQRILDNCQIKPANLQIENH 188
>UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1;
Lactobacillus acidophilus|Rep: Reductase-dehydrogenase -
Lactobacillus acidophilus
Length = 271
Score = 71.7 bits (168), Expect = 2e-11
Identities = 50/154 (32%), Positives = 79/154 (51%), Gaps = 3/154 (1%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
S+ +NNG +P I GT+L + ++ VV +A+++G R FDTA Y E+
Sbjct: 6 SVILNNGEKIPQIQLGTWL---------INNDEVNKVVRQAVNIGYRGFDTAKDYGNESG 56
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP- 421
V + ++R DIF+TTKL +AI+ +L K GL+YIDL L+H P
Sbjct: 57 ----VGKGIWNSDIERSDIFLTTKLPTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQ 112
Query: 422 --IGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
I +N +E WR +E+A + G +++
Sbjct: 113 PWIEVNRTNDRHFKGNLENWRAMEEAVKAGKVRS 146
Score = 39.9 bits (89), Expect = 0.058
Identities = 16/35 (45%), Positives = 24/35 (68%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G ++ IG+SNF ++ +E ++ GTI P QIEVH
Sbjct: 142 GKVRSIGVSNFLQEDIENIVNNGTITPAVNQIEVH 176
>UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 275
Score = 71.7 bits (168), Expect = 2e-11
Identities = 52/150 (34%), Positives = 74/150 (49%)
Frame = +2
Query: 68 LKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRN 247
+K+NNG P G+Y+ V ++K D V A+ G RH D+A +Y E
Sbjct: 6 VKLNNGLKCPQFAYGSYM------VNRTK---CFDSVYAALQCGYRHIDSAQMYHNEADC 56
Query: 248 WRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 427
R + +EE KREDI+ T+KL N +I+ S+K GL YIDL+L+H P G
Sbjct: 57 GRAILKFMEETGTKREDIWFTSKL-NDLSGYKSTLSSIDASVKACGLGYIDLFLLHSPYG 115
Query: 428 LNADYSHSDVDFMETWRGLEDAQRMGILKA 517
D +E+W+ LE G L+A
Sbjct: 116 ----------DRIESWKALEKGVEEGKLRA 135
>UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein;
n=1; Thermoplasma acidophilum|Rep: Alcohol dehydrogenase
related protein - Thermoplasma acidophilum
Length = 284
Score = 71.7 bits (168), Expect = 2e-11
Identities = 42/113 (37%), Positives = 61/113 (53%)
Frame = +2
Query: 83 GRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVK 262
GR + IG GT+ + S+ + +R + A+D G DTA +Y TE +K
Sbjct: 13 GRKVSVIGVGTW------SLEGSRSENVRSI-RYALDHGVNFIDTAEMYGTEDIVGEAIK 65
Query: 263 MKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 421
+RED+FI TK+W T +V ++ +SLKKLG DY+DLY +HWP
Sbjct: 66 G------YRREDLFIATKVWPTHFAYHDVLKSCEESLKKLGTDYVDLYQLHWP 112
>UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6;
n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 -
Apis mellifera
Length = 292
Score = 71.3 bits (167), Expect = 2e-11
Identities = 50/157 (31%), Positives = 82/157 (52%), Gaps = 4/157 (2%)
Frame = +2
Query: 59 VPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQL-RDVVMRAIDVG*RHFDTASVYET 235
V ++ +++G DMP IG GTY K + ++L VV +++VG R DTA Y
Sbjct: 5 VRNVCLSSGYDMPLIGFGTY---------KIQGRELVYQVVDESLNVGFRSIDTAVGYRN 55
Query: 236 ETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTE-VAQAINDSLKKLGLDYIDLYLM 412
E +K + + ++R DIFITTKL + + + + Q + SLK YIDLYL+
Sbjct: 56 EEDIGYALKNLLPKYNLQRSDIFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYLI 115
Query: 413 HWPIGLNADYSHSDVDFM--ETWRGLEDAQRMGILKA 517
HWP + ++ + +TW L D ++ G +++
Sbjct: 116 HWPGATRIPETSTNNPSLRAKTWNKLVDLKKQGFIRS 152
>UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1;
Helicobacter hepaticus|Rep: Putative uncharacterized
protein - Helicobacter hepaticus
Length = 270
Score = 71.3 bits (167), Expect = 2e-11
Identities = 55/150 (36%), Positives = 76/150 (50%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
+L +NNG MP +G GTY G K+ K + + AI+VG R FD+A +Y E
Sbjct: 3 TLTLNNGVKMPILGLGTY---SLTG--KAGQKAMSE----AIEVGYRLFDSAQMYNNEAE 53
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
+ V+ G+ KRE+ FI TKL + ++I SLK LGLDYID L+H P
Sbjct: 54 LGAAINAAVKGGI-KREEFFIQTKLLESSSEDL-AKKSIEKSLKTLGLDYIDSLLIHMP- 110
Query: 425 GLNADYSHSDVDFMETWRGLEDAQRMGILK 514
YS S +R +E + GIL+
Sbjct: 111 -----YSQSKA----MYRAMESFYKQGILR 131
>UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1;
Erythrobacter sp. SD-21|Rep: Putative oxidoreductase
protein - Erythrobacter sp. SD-21
Length = 272
Score = 71.3 bits (167), Expect = 2e-11
Identities = 46/154 (29%), Positives = 77/154 (50%)
Frame = +2
Query: 56 EVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYET 235
+ P+L +N+GR +P +G GT+ + +++ V AIDVG DTA++Y
Sbjct: 3 DYPTLNLNDGRQIPQLGFGTW---------QMEEEDAPQAVSTAIDVGYWLIDTAAIYGN 53
Query: 236 ETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 415
E V +GV + DIF+ TK+WN +A L++LG +++D+ L+H
Sbjct: 54 EKG--------VGKGVGEWSDIFLQTKIWNDSQGYDRTLRAAEKCLERLGREHVDMLLIH 105
Query: 416 WPIGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
WP D F++TW+ L + + G K+
Sbjct: 106 WPC------PEKD-QFVDTWKALIELRDAGKAKS 132
Score = 35.9 bits (79), Expect = 0.94
Identities = 15/35 (42%), Positives = 23/35 (65%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G K IG+SNF ++ L+R++ E + P QIE+H
Sbjct: 128 GKAKSIGVSNFREEDLKRIIDETGVTPALNQIELH 162
>UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Shewanella sp. (strain ANA-3)
Length = 280
Score = 71.3 bits (167), Expect = 2e-11
Identities = 42/127 (33%), Positives = 67/127 (52%), Gaps = 3/127 (2%)
Frame = +2
Query: 137 GVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKVEEGVVKREDIFITTK 316
G + KD D V+ A++ G RH DTA +Y E + V + + RE++FITTK
Sbjct: 23 GTFRLKDNAAFDAVLMALEEGSRHIDTAQIYGNE----QAVGDAINTSGIPREELFITTK 78
Query: 317 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLED-- 490
+W + ++ DSL L Y+DL L+HWP LN+D S V+++ + + D
Sbjct: 79 VWTENLTKERFETSVIDSLTALQTKYLDLLLIHWP--LNSD-EPSMVEYLSELKAVLDKG 135
Query: 491 -AQRMGI 508
+R+G+
Sbjct: 136 LTRRIGV 142
>UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia
ATCC 50803
Length = 313
Score = 71.3 bits (167), Expect = 2e-11
Identities = 47/147 (31%), Positives = 70/147 (47%), Gaps = 15/147 (10%)
Frame = +2
Query: 119 LGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVK--MKVEEGVVKR 292
LGF G ++ + ++ V A+ G RH D A VY+ E R K +KR
Sbjct: 7 LGF---GTWQAPPEAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKR 63
Query: 293 EDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL----NADYSHSD-- 454
ED++IT+KLWN HR V + ++ L +DY+DL+L+HWP+ D D
Sbjct: 64 EDVWITSKLWNYNHRPELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAE 123
Query: 455 -------VDFMETWRGLEDAQRMGILK 514
V +TWR +E G++K
Sbjct: 124 GRAMLEKVPLADTWRAMEQLVEEGLVK 150
>UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1;
Klebsiella pneumoniae|Rep: Putative uncharacterized
protein - Klebsiella pneumoniae
Length = 279
Score = 69.3 bits (162), Expect = 8e-11
Identities = 44/155 (28%), Positives = 79/155 (50%)
Frame = +2
Query: 53 MEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYE 232
M S+ +N+G MP G G +L + ++D + ++ +A+ G RHFDTA Y
Sbjct: 1 MTTDSILLNDGYYMPRPGCGLWL-------IDNRD--VDSLIRQALKAGFRHFDTAQAYF 51
Query: 233 TETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 412
E R ++ V RE +FIT+K+ + N++L++LG++Y++L+L+
Sbjct: 52 NEDGVGRALRYTE----VPREQLFITSKIRGRDMGYARTLVSFNETLERLGVEYLELFLI 107
Query: 413 HWPIGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
HWPI Y +ETW + + G++++
Sbjct: 108 HWPIPAKNLY-------VETWEASIELEASGLIRS 135
Score = 37.5 bits (83), Expect = 0.31
Identities = 15/37 (40%), Positives = 26/37 (70%)
Frame = +1
Query: 496 ANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
A+G I+ IG+SNF Q +ER++++ + P Q+E+H
Sbjct: 129 ASGLIRSIGVSNFTCQHIERLIEDTGVVPAVNQLELH 165
>UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase;
n=1; Rhodococcus sp. RHA1|Rep: Probable
2,5-didehydrogluconate reductase - Rhodococcus sp.
(strain RHA1)
Length = 265
Score = 69.3 bits (162), Expect = 8e-11
Identities = 34/83 (40%), Positives = 52/83 (62%)
Frame = +2
Query: 176 VMRAIDVG*RHFDTASVYETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQ 355
V+ I+ G R DTA++Y+ E V + + E V RE++F+TTKL + H ++
Sbjct: 23 VLSGIEAGYRLIDTATIYDNED----AVGVALAECGVPREELFVTTKLRGSDHVSGDIRG 78
Query: 356 AINDSLKKLGLDYIDLYLMHWPI 424
A+ SLK LGLD +DL+L+HWP+
Sbjct: 79 AVERSLKNLGLDRLDLFLIHWPL 101
>UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4;
Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 287
Score = 68.5 bits (160), Expect = 1e-10
Identities = 45/154 (29%), Positives = 74/154 (48%)
Frame = +2
Query: 56 EVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYET 235
++P LK+ +G +P +G GT+ + + V A+ G R DTA Y
Sbjct: 12 DIPRLKLPHGHTIPRLGLGTW---------PMLEDECETAVRFALQSGYRLVDTAFQY-- 60
Query: 236 ETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 415
RN V + V R ++FI++K H V +A ++SL+KLGLD++D+++ H
Sbjct: 61 --RNEEAVGRGIRTAGVPRSELFISSKFNKESHSIDGVQRAYDESLRKLGLDHLDMFMCH 118
Query: 416 WPIGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
WP+ Y ++ W+GL G +KA
Sbjct: 119 WPVPALGKY-------VDAWKGLVKLLEEGRVKA 145
>UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid
reductase; n=1; Gluconobacter oxydans|Rep: Putative
2,5-diketo-D-gluconic acid reductase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 279
Score = 68.1 bits (159), Expect = 2e-10
Identities = 43/150 (28%), Positives = 73/150 (48%)
Frame = +2
Query: 68 LKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRN 247
+ ++G MP IG G + ++ + +VV A+ +G R DTA +Y+ E
Sbjct: 14 ISFHDGHTMPQIGLGVW---------ETPPDETAEVVKEAVKLGYRSVDTARLYKNEEG- 63
Query: 248 WRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 427
V +G+ +IF+TTKLWN + +A +S + L +DLYL+HWP+
Sbjct: 64 -------VGKGLEDHPEIFLTTKLWNDEQGYDSTLRAYEESARLLRRPVLDLYLIHWPMP 116
Query: 428 LNADYSHSDVDFMETWRGLEDAQRMGILKA 517
Y +ETW+ L + ++ G +K+
Sbjct: 117 AQGQY-------VETWKALVELKKSGRVKS 139
Score = 36.3 bits (80), Expect = 0.71
Identities = 15/36 (41%), Positives = 23/36 (63%)
Frame = +1
Query: 499 NGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
+G +K IG+SNF + LER++ + P QIE+H
Sbjct: 134 SGRVKSIGVSNFESEHLERIMDATGVVPVVNQIELH 169
>UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:
Aldo/keto reductase - Kineococcus radiotolerans SRS30216
Length = 343
Score = 68.1 bits (159), Expect = 2e-10
Identities = 37/121 (30%), Positives = 62/121 (51%)
Frame = +2
Query: 59 VPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETE 238
VP ++ G +PAIG GT+ G + ++ V A+ G R D A+VY E
Sbjct: 13 VPRRELRGGATVPAIGIGTF------GSDRYSPAEVAAAVAGAVAAGYRLVDCAAVYGNE 66
Query: 239 TRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 418
+ + V GV R+++F+ +K+WN H + +++ SL+ L LD++D +HW
Sbjct: 67 AQVGEALAGAVAGGV-DRDELFVVSKVWNDAHAPADAVASVHRSLRDLRLDHLDAVFVHW 125
Query: 419 P 421
P
Sbjct: 126 P 126
>UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 275
Score = 68.1 bits (159), Expect = 2e-10
Identities = 33/96 (34%), Positives = 56/96 (58%)
Frame = +2
Query: 137 GVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKVEEGVVKREDIFITTK 316
G+ +K + V+ A++ G R DTA+ Y E R V + E V R ++++ TK
Sbjct: 21 GLYDLDEKHTKQAVLWALENGYRMIDTAASYNNEKR----VGEALRESAVPRSEVYLVTK 76
Query: 317 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
+++T H + +A + SL LG+DY+DLYL+H+P+
Sbjct: 77 VYHTDHGYEKTMKAYDRSLSALGVDYVDLYLIHFPV 112
Score = 36.3 bits (80), Expect = 0.71
Identities = 18/47 (38%), Positives = 22/47 (46%)
Frame = +1
Query: 466 GDLARIGRCSANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G + G + IG+SNFN LE + K I P QIEVH
Sbjct: 118 GSWEAMAELQGKGLTRSIGVSNFNIHHLEALQKHSVIPPVVNQIEVH 164
>UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Streptococcus agalactiae|Rep:
Oxidoreductase, aldo/keto reductase family -
Streptococcus agalactiae H36B
Length = 245
Score = 67.7 bits (158), Expect = 3e-10
Identities = 43/118 (36%), Positives = 64/118 (54%)
Frame = +2
Query: 74 MNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWR 253
+NNG +P++G G + D +S V+ A+ VG R DTAS Y E R
Sbjct: 9 LNNGVKIPSLGFGVFQIDDPLECEQS--------VLDALQVGYRLIDTASGYLNEEAVGR 60
Query: 254 TVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 427
+K + + R++IF+ TKLW + AI+ +LK+L LDYI+LYL+H P+G
Sbjct: 61 AIK----KSGIPRKEIFVVTKLWIQDASEEKAGPAIDRALKRLQLDYINLYLIHQPMG 114
>UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 287
Score = 67.7 bits (158), Expect = 3e-10
Identities = 44/144 (30%), Positives = 74/144 (51%), Gaps = 1/144 (0%)
Frame = +2
Query: 89 DMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMK 268
+MP IG GT+ K++ LR V+ G R DTA VY E + R ++
Sbjct: 10 NMPLIGIGTWQ--------VQKEEILRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEKL 61
Query: 269 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP-IGLNADYS 445
+ +KREDI+IT+KL + + ++I +SL L ++Y+DL L+HWP L ++
Sbjct: 62 LPANGLKREDIWITSKLAPSNAGVKKARESIEESLSNLKVEYLDLLLIHWPGSSLKSENP 121
Query: 446 HSDVDFMETWRGLEDAQRMGILKA 517
+ +E+W + + G L++
Sbjct: 122 ANKKLRVESWNVMCEMMAEGKLRS 145
Score = 33.5 bits (73), Expect = 5.0
Identities = 27/97 (27%), Positives = 41/97 (42%), Gaps = 5/97 (5%)
Frame = +1
Query: 331 APEN*SSPSYKRFTEETRSGLYRSLFDALA-HWIKCRL*S---FGRRLHGDLARIG-RCS 495
AP N + EE+ S L D L HW L S ++L + +
Sbjct: 79 APSNAGVKKARESIEESLSNLKVEYLDLLLIHWPGSSLKSENPANKKLRVESWNVMCEMM 138
Query: 496 ANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
A G ++ +G+SNF LE + K+ + P Q+E H
Sbjct: 139 AEGKLRSVGVSNFEICHLEELKKDSNVVPAVNQVEYH 175
>UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 287
Score = 67.7 bits (158), Expect = 3e-10
Identities = 45/153 (29%), Positives = 82/153 (53%), Gaps = 4/153 (2%)
Frame = +2
Query: 71 KMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNW 250
K+ NG+++P + GTY ++K QL V A+ VG R FDTA YE E
Sbjct: 3 KLKNGQEIPKLALGTY---------EAKGDQLFAAVDEALKVGYRSFDTAKYYENEKDLG 53
Query: 251 RTVKMKVEEGVVKREDIFITTKL--WNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
+K + + EDI++T+K+ +++++ + + +N+SL+ L Y+DL L+H+P
Sbjct: 54 LALKTLLPRHNICSEDIYLTSKVFPYSSKNAAELIRKDVNESLELLDRKYLDLVLVHYPR 113
Query: 425 GLNA-DYSHSDVDF-METWRGLEDAQRMGILKA 517
L+ D + ++ + +TW LE G +++
Sbjct: 114 PLDTEDLNENNKMYRKDTWIALEKLHAEGKIRS 146
Score = 34.3 bits (75), Expect = 2.9
Identities = 17/43 (39%), Positives = 23/43 (53%)
Frame = +1
Query: 496 ANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSKTFRK 624
A G I+ IG+SN+ +E + TI+P QIE H RK
Sbjct: 140 AEGKIRSIGVSNYEPHHIEEMRSYITIEPQVNQIEYHPHFQRK 182
>UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Rep:
YvgN - Bacillus sp. NRRL B-14911
Length = 268
Score = 67.3 bits (157), Expect = 3e-10
Identities = 50/154 (32%), Positives = 74/154 (48%), Gaps = 4/154 (2%)
Frame = +2
Query: 68 LKMNNGRDMPAIGXGTYL-GFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
+ +NNG +MP +G GT G + N ++ ++ AI++G R D A +Y R
Sbjct: 4 ITLNNGLEMPIVGTGTNTYGKENNDYNGDLTNEIPELAS-AIELGYRSIDAAIMY----R 58
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQH---RRTEVAQAINDSLKKLGLDYIDLYLMH 415
N V + E V RE+ FITTK+ ++ + AI++SLK DY+DL L+H
Sbjct: 59 NEELVGSVLAESKVPREEFFITTKIPASEEYISSKEATRAAIDNSLKNFQTDYLDLLLIH 118
Query: 416 WPIGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
+PI V TW E+ G LKA
Sbjct: 119 FPI-------EDKVQLKNTWEVFEEYYEAGKLKA 145
>UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 273
Score = 67.3 bits (157), Expect = 3e-10
Identities = 33/95 (34%), Positives = 49/95 (51%)
Frame = +2
Query: 137 GVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKVEEGVVKREDIFITTK 316
G + K + V A+DVG RH DTA YE E V + + R ++F+TTK
Sbjct: 17 GTYRLKGDDAKLAVENALDVGYRHIDTAQAYENEAE----VGDAISASKISRGELFVTTK 72
Query: 317 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 421
+W + ++ +SL +L DY+DL L+HWP
Sbjct: 73 VWFDNLSADKFITSVQNSLTQLNTDYVDLLLVHWP 107
>UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 301
Score = 67.3 bits (157), Expect = 3e-10
Identities = 50/158 (31%), Positives = 84/158 (53%), Gaps = 7/158 (4%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDV-VMRAIDVG*RHFDTASVYETET 241
+ K ++G +MP IG G + + + +Q DV + A+ G R FDTA++Y+ ET
Sbjct: 11 AFKFSDGYEMPKIGLG---------ISRIETQQDLDVSIEAALKSGYRQFDTANLYKNET 61
Query: 242 RNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRT--EVAQAINDSLKKLGLDYIDLYLMH 415
++K + + + RED+FITTK+ T + T E + + +SL L DY+DL L+H
Sbjct: 62 FLGNSLKKYLPQFGLTREDVFITTKV-RTLNENTVEETEKQLANSLATLQTDYVDLLLIH 120
Query: 416 WP----IGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
+P G + DY + W+ LE A+ G +++
Sbjct: 121 YPRDRDTGNDDDYEINKSRRKIVWQTLEKAKESGRVRS 158
>UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 353
Score = 66.9 bits (156), Expect = 4e-10
Identities = 41/121 (33%), Positives = 69/121 (57%)
Frame = +2
Query: 71 KMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNW 250
++++G + P +G GT+ G +++ L V+ A++ G H DT+ VY+ E
Sbjct: 32 RLSSGHNFPIVGLGTH-GLNED--------VLETVLTGALEKGIGHIDTSFVYKNEETIG 82
Query: 251 RTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 430
+ +K +G KREDIF+T+KL + V + I SL+KLGL Y+D+YL+H P +
Sbjct: 83 KVLKDWFAKGG-KREDIFVTSKLPYYDNHPESVEKYIKLSLEKLGLQYLDMYLIHAPFAV 141
Query: 431 N 433
+
Sbjct: 142 H 142
Score = 47.6 bits (108), Expect = 3e-04
Identities = 20/36 (55%), Positives = 26/36 (72%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHS 609
G K IGLSNFN+ Q+ +LKE IKP +Q+EVH+
Sbjct: 180 GRTKSIGLSNFNETQITNILKEAKIKPSNLQVEVHA 215
>UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4;
Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia
sp. (strain CCS1)
Length = 276
Score = 66.9 bits (156), Expect = 4e-10
Identities = 38/152 (25%), Positives = 77/152 (50%)
Frame = +2
Query: 62 PSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETET 241
P +K ++G +P +G G + + + V AI++G R D A +Y E
Sbjct: 5 PVIKFHDGAQIPQVGFGIW---------QVPQDIAGETVRSAIEIGYRMIDGAYLYMNEA 55
Query: 242 RNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 421
++ + R+++F+TTK+WN + + ++ SLK +G++ +DL L+HWP
Sbjct: 56 GLGEGLRASG----LPRDEVFVTTKVWNNEQGAAKARASVERSLKTIGVEQLDLVLIHWP 111
Query: 422 IGLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
+ D+ ++ETW+ +D + G++++
Sbjct: 112 V------PSQDL-YLETWKAFQDMRDEGLMRS 136
>UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6;
Halobacteriaceae|Rep: Aldehyde reductase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 279
Score = 66.9 bits (156), Expect = 4e-10
Identities = 38/112 (33%), Positives = 57/112 (50%)
Frame = +2
Query: 92 MPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKV 271
MP +G GT+ D +Q + V A++ G RH DTA Y+ E+ V +
Sbjct: 17 MPMLGLGTWQNEDA--------EQCAESVRTALEAGYRHIDTAQAYDNES----AVGDGI 64
Query: 272 EEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 427
V R+DIF+ TK+W + +V + +SL KLG+D +DL +HW G
Sbjct: 65 AAADVDRDDIFLATKVWISNLSHDDVIETTEESLDKLGVDSVDLLYVHWAAG 116
>UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,
putative; n=3; Bacteria|Rep: 2,5-diketo-D-gluconic acid
reductase B, putative - Roseobacter denitrificans
(strain ATCC 33942 / OCh 114) (Erythrobactersp. (strain
OCh 114)) (Roseobacter denitrificans)
Length = 272
Score = 66.5 bits (155), Expect = 6e-10
Identities = 34/95 (35%), Positives = 52/95 (54%)
Frame = +2
Query: 137 GVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKVEEGVVKREDIFITTK 316
G K RD ++ A +VG R FDTA +Y E +K E G+ R+ + +TTK
Sbjct: 14 GTYPLKGTACRDAILTAAEVGYRAFDTAQMYRNEAETGAALK---ETGI-PRDTLCVTTK 69
Query: 317 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 421
+ N + ++ ++ SLK L LDY+D+ L+HWP
Sbjct: 70 VENDNYDESKFLASVEASLKALQLDYVDVLLLHWP 104
>UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus
pacificus|Rep: Aldose reductase - Pristionchus pacificus
Length = 293
Score = 66.5 bits (155), Expect = 6e-10
Identities = 43/121 (35%), Positives = 62/121 (51%)
Frame = +2
Query: 92 MPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKV 271
MP IG GTY V+S+ L D + A +G R DTA +Y E R + +
Sbjct: 16 MPMIGVGTYQ-------VQSQSV-LTDTIDEAFRLGYRFIDTAQIYRNEAILGRILPDLL 67
Query: 272 EEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHS 451
E+ +KREDIFIT+K+ + + ++++ SL L YIDL L+HWP +H
Sbjct: 68 EKHSLKREDIFITSKVSPINQGKGKTSKSVLKSLTDLQTPYIDLVLIHWPGTSRLKSNHK 127
Query: 452 D 454
D
Sbjct: 128 D 128
>UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 282
Score = 66.1 bits (154), Expect = 8e-10
Identities = 42/117 (35%), Positives = 59/117 (50%), Gaps = 3/117 (2%)
Frame = +2
Query: 176 VMRAIDVG*RHFDTASVYETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQ 355
V A+ G RH DTA Y+ E +V + + + RE IF+TTKL
Sbjct: 36 VRAALAAGYRHIDTALAYQNEA----SVGQAIRDSGIPREQIFVTTKLPAETKSYQGALN 91
Query: 356 AINDSLKKLGLDYIDLYLMH--WPIG-LNADYSHSDVDFMETWRGLEDAQRMGILKA 517
+ SLK LGLDY+DLYL+H WP G + Y +++D W+ +E + G KA
Sbjct: 92 DFDRSLKNLGLDYVDLYLVHAPWPWGQVGRVYDEANLD---VWQAMEAIYQSGRAKA 145
>UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 234
Score = 66.1 bits (154), Expect = 8e-10
Identities = 28/54 (51%), Positives = 38/54 (70%)
Frame = +2
Query: 284 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYS 445
VK DI++TTK+WN + + V ++NDSLKKL LDY+ L+L+HWPI YS
Sbjct: 104 VKGPDIWVTTKVWNHLYDKDGVQWSLNDSLKKLNLDYVGLFLIHWPISCEKAYS 157
>UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 287
Score = 66.1 bits (154), Expect = 8e-10
Identities = 48/148 (32%), Positives = 73/148 (49%), Gaps = 2/148 (1%)
Frame = +2
Query: 80 NGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTV 259
NG +PA G G YL Q +V +A+DVG R DTA YE E +
Sbjct: 14 NGSRIPACGVGVYL---------LPASQTAGIVEKALDVGYRLIDTAQEYENERETGEGI 64
Query: 260 KMKV-EEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKL-GLDYIDLYLMHWPIGLN 433
K + ++ KRED+ TTK+ N +++ +SL K+ L+YIDL L+H P+
Sbjct: 65 KAWLGKDKNNKREDVLYTTKITNLNQGYDRTWRSLKESLNKVKHLEYIDLVLIHDPLS-- 122
Query: 434 ADYSHSDVDFMETWRGLEDAQRMGILKA 517
+ETW+ L++A G++K+
Sbjct: 123 -----DKKTRIETWKALQEAVDSGMVKS 145
>UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1;
Actinobacillus succinogenes 130Z|Rep: Aldo/keto
reductase precursor - Actinobacillus succinogenes 130Z
Length = 315
Score = 65.7 bits (153), Expect = 1e-09
Identities = 44/119 (36%), Positives = 63/119 (52%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
++K+NNG +MP IG G + +Q V A+ G R DTA +Y R
Sbjct: 44 TVKLNNGIEMPIIGIGVWT---------LTPEQTEKSVGEALKAGYRLIDTARMY----R 90
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 421
N + V V + + RE+IFITTK++ + A AIN+ L+ L DYIDL L+H+P
Sbjct: 91 NEQAVGRAVRDSGIPREEIFITTKIYGSGDYANAEA-AINERLRLLDTDYIDLLLLHYP 148
Score = 38.3 bits (85), Expect = 0.18
Identities = 15/35 (42%), Positives = 24/35 (68%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G I+ IGLSN++++ R+++ TI P +Q EVH
Sbjct: 166 GKIRAIGLSNYHRKTFNRIMQAATITPAVVQNEVH 200
>UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1;
Sulfitobacter sp. NAS-14.1|Rep: Putative uncharacterized
protein - Sulfitobacter sp. NAS-14.1
Length = 274
Score = 65.7 bits (153), Expect = 1e-09
Identities = 36/101 (35%), Positives = 54/101 (53%)
Frame = +2
Query: 119 LGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKVEEGVVKRED 298
LGF G + + + D+V A+ G RH DTA Y+ E + V + V+R++
Sbjct: 14 LGF---GTFQLEQDTVADMVAAALSEGFRHIDTAQAYQNEEQ----VGEGLRRADVRRDE 66
Query: 299 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 421
+F+TTK+ A + SLK+LG DY+DL L+HWP
Sbjct: 67 VFLTTKILPEHFSPEAFTAAADASLKRLGTDYVDLLLLHWP 107
>UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 297
Score = 65.7 bits (153), Expect = 1e-09
Identities = 45/156 (28%), Positives = 80/156 (51%), Gaps = 5/156 (3%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
S K+N+G ++P +G GTY K + + + A+ G R FDTA Y E
Sbjct: 12 SQKLNSGYNIPFVGFGTY---------KVTGENVPPAIDAALTAGYRMFDTAKYYLNEKE 62
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQA-INDSLKKLGLDYIDLYLMHWP 421
+K+ + + + R D+F+T+K + E + + +SL+ L DYID+YL+H+P
Sbjct: 63 LGEALKILLPKHGLSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYP 122
Query: 422 IGLNADYSHSDVDFME----TWRGLEDAQRMGILKA 517
++D + DV+ E + LE+A+ G +++
Sbjct: 123 KPNDSD--NDDVNNAEYRKIAYEVLEEAKAAGKVRS 156
>UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 264
Score = 64.9 bits (151), Expect = 2e-09
Identities = 38/116 (32%), Positives = 61/116 (52%)
Frame = +2
Query: 74 MNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWR 253
+N+GR MP G G + + DV + A+ G R DTA +Y+ E +
Sbjct: 15 LNDGRKMPLFGLGVF----------RLETGCEDVCLFALKNGYRMLDTADIYQNE----K 60
Query: 254 TVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 421
V V + +KREDI++TTKL ++ + + +S+KKL + Y+DL+L+H P
Sbjct: 61 EVGSAVRKSGLKREDIYVTTKLKPSEEGHSNALKYAKESIKKLDIGYVDLFLIHTP 116
>UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase family;
n=1; Mycoplasma penetrans|Rep: Oxidoreductase-aldo/keto
reductase family - Mycoplasma penetrans
Length = 299
Score = 64.5 bits (150), Expect = 2e-09
Identities = 41/121 (33%), Positives = 64/121 (52%), Gaps = 1/121 (0%)
Frame = +2
Query: 62 PSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETET 241
P L +N+G +P IG GT ++ ++ + A+++G R FDTAS+Y E
Sbjct: 35 PLLTLNDGYQIPIIGLGT---------TSLHNQTCKNAIKAALEIGIRLFDTASLYGNEK 85
Query: 242 RNWRTVKMKVEEGVVKREDIFITTKLW-NTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 418
T++ E + R +IF+ TKL+ Q E +AI ++L KL DYID+ L+H
Sbjct: 86 EVGETIR----ESNINRNEIFVITKLYPGAQFANPE--KAIEEALNKLNTDYIDMMLLHH 139
Query: 419 P 421
P
Sbjct: 140 P 140
Score = 33.5 bits (73), Expect = 5.0
Identities = 15/35 (42%), Positives = 22/35 (62%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G IK +GLSN+ +++ L + IKP IQ E+H
Sbjct: 158 GKIKSVGLSNWYIKEINSFLPQINIKPSLIQNEIH 192
>UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 326
Score = 64.5 bits (150), Expect = 2e-09
Identities = 45/150 (30%), Positives = 70/150 (46%)
Frame = +2
Query: 68 LKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRN 247
L+MN+G ++P +G G Y ++ Q D+V +A D G RH D+A+ Y RN
Sbjct: 46 LRMNSGYEIPILGYGVY---------QTPASQCEDLVAKAFDAGYRHVDSAAAY----RN 92
Query: 248 WRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 427
+ + REDIF T+K+ + +L + GL YIDL L+H P G
Sbjct: 93 EGPCAAAIRRSSIPREDIFFTSKIPPRSLSYENTKAQVAKTLMETGLGYIDLMLIHAPYG 152
Query: 428 LNADYSHSDVDFMETWRGLEDAQRMGILKA 517
A + W+ L +AQ G +++
Sbjct: 153 GRAARKGA-------WKALVEAQEEGKIRS 175
>UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2;
Halobacteriaceae|Rep: Alcohol dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 667
Score = 64.5 bits (150), Expect = 2e-09
Identities = 33/87 (37%), Positives = 44/87 (50%)
Frame = +2
Query: 170 DVVMRAIDVG*RHFDTASVYETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 349
D + A+D G R D+A +Y E R R + G R +FI K+W T HRR +
Sbjct: 398 DSIAAALDAGYRLLDSAELYGNEHRIGRIL---AAPGAPDRRRVFILGKVWRTNHRRKHM 454
Query: 350 AQAINDSLKKLGLDYIDLYLMHWPIGL 430
A SL +LG+D D Y +HWP L
Sbjct: 455 LTACRSSLDELGIDAFDCYALHWPEAL 481
Score = 37.9 bits (84), Expect = 0.23
Identities = 14/35 (40%), Positives = 25/35 (71%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G+ + +GL N ++ QLE V++ GT++P +Q+E H
Sbjct: 532 GWTRTLGLCNVSQTQLETVIETGTVRPALVQVERH 566
>UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG07276.1 - Gibberella zeae PH-1
Length = 284
Score = 64.1 bits (149), Expect = 3e-09
Identities = 48/149 (32%), Positives = 79/149 (53%), Gaps = 5/149 (3%)
Frame = +2
Query: 77 NNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRT 256
N+ +P IG G+Y K + + V+ A+ G RH D+A++Y E R
Sbjct: 15 NSTSIIPCIGFGSY---------KIRGETCAAAVLAALPAGYRHIDSAALYRNEVR---- 61
Query: 257 VKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKL----GLD-YIDLYLMHWP 421
V+ +E+ V RED+F+TTK+ + R+TE +A D ++ + G D Y+DL LMH P
Sbjct: 62 VREAIEQSGVFREDLFLTTKV-GSPRRKTEKTEAYEDVIEAVERIAGKDGYVDLLLMHVP 120
Query: 422 IGLNADYSHSDVDFMETWRGLEDAQRMGI 508
G + ++ HS + ME + A+ +G+
Sbjct: 121 -GPSREHRHSLWEAMERAKREARARNIGV 148
>UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 282
Score = 64.1 bits (149), Expect = 3e-09
Identities = 43/120 (35%), Positives = 63/120 (52%)
Frame = +2
Query: 68 LKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRN 247
+ +NNG +P +G GTYL ++ D Q V A+D DTA+VY E
Sbjct: 4 ITLNNGITIPQVGLGTYL-------LEPDDAQ--SAVTYALDNDYTLIDTANVYVNE--- 51
Query: 248 WRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 427
R V + R++IF+ TKLW + R A A+ ++L++LG DYIDL ++H P G
Sbjct: 52 -RAVGRGMRASSKARDEIFLETKLWPSFFER---ASAVEETLERLGTDYIDLMILHQPAG 107
Score = 35.9 bits (79), Expect = 0.94
Identities = 16/35 (45%), Positives = 22/35 (62%)
Frame = +1
Query: 502 GYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
G I+ IGLSNF+ Q +R+L E + P Q+E H
Sbjct: 123 GKIRAIGLSNFDVAQTQRILDECEVVPTINQVECH 157
>UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina
baltica OS145|Rep: Aldo/keto reductase - Idiomarina
baltica OS145
Length = 263
Score = 64.1 bits (149), Expect = 3e-09
Identities = 40/126 (31%), Positives = 63/126 (50%)
Frame = +2
Query: 137 GVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKVEEGVVKREDIFITTK 316
G + + ++L D+V AID+G H DTA Y E + + + D+F+TTK
Sbjct: 8 GTFRLEGQELTDLVSAAIDMGYEHIDTAQFYGNEADVGKALAQHTNK------DVFVTTK 61
Query: 317 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 496
+W + +V ++ S KL D IDL L+HWP + +V ET L+ AQ
Sbjct: 62 VWYEKLAYQDVLDSLQVSRDKLQRDTIDLALIHWP------SPNDEVPVEETLDALQKAQ 115
Query: 497 RMGILK 514
+ G++K
Sbjct: 116 QDGLIK 121
>UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1;
Candida parapsilosis|Rep: Conjugated polyketone
reductase C2 - Candida parapsilosis (Yeast)
Length = 307
Score = 64.1 bits (149), Expect = 3e-09
Identities = 41/151 (27%), Positives = 79/151 (52%), Gaps = 4/151 (2%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
+ + +G+++ +I GT + Q + +L D ++ + +G RH DTA Y T+
Sbjct: 10 TFRTKSGKEI-SIALGTGTKWKQAQTINDVSTELVDNILLGLKLGFRHIDTAEAYNTQ-- 66
Query: 245 NWRTVKMKVEEGVVKREDIFITTKL---WNTQHRRTEV-AQAINDSLKKLGLDYIDLYLM 412
+ V ++ V REDI++TTK W + ++ + +I+ +L +LG+DY+DL+L+
Sbjct: 67 --KEVGEALKRTDVPREDIWVTTKYSPGWGSIKAYSKSPSDSIDKALAQLGVDYVDLFLI 124
Query: 413 HWPIGLNADYSHSDVDFMETWRGLEDAQRMG 505
H P + +H + W L +A++ G
Sbjct: 125 HSPF-FTTEQTHG-YTLEQAWEALVEAKKAG 153
>UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 355
Score = 64.1 bits (149), Expect = 3e-09
Identities = 30/73 (41%), Positives = 46/73 (63%)
Frame = +2
Query: 212 DTASVYETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLD 391
D A +Y E V ++ V R ++F+TTK+W T HR+ E +++SL++LGLD
Sbjct: 80 DAAWIYGNENE----VGQGIKASGVPRSELFVTTKIWCTYHRQPEAC--LDESLQRLGLD 133
Query: 392 YIDLYLMHWPIGL 430
Y+DL L+HWP+ L
Sbjct: 134 YVDLLLVHWPVPL 146
>UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 289
Score = 64.1 bits (149), Expect = 3e-09
Identities = 46/151 (30%), Positives = 74/151 (49%)
Frame = +2
Query: 53 MEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYE 232
M++P L++ +G +P T G G+V D+ I+ G H D A +Y
Sbjct: 1 MDIPLLRLRDGNQIPLDLGDTTFG---QGLV--------DLTKAVIEKGFYHLDCAEMYG 49
Query: 233 TETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 412
TE V + ++E V RE +FIT K+ ++ AI+ SL+K+ +Y DLYL+
Sbjct: 50 TEEE----VAIAIKESGVPREKLFITNKV---AQGIDDIEAAIDQSLQKMQTNYFDLYLI 102
Query: 413 HWPIGLNADYSHSDVDFMETWRGLEDAQRMG 505
H P ++ S+ DF W+ +E Q+ G
Sbjct: 103 HIPF-----FAKSEEDFQRAWKTMEGIQKAG 128
>UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep:
Aldo/keto reductase - Mesorhizobium sp. (strain BNC1)
Length = 308
Score = 63.7 bits (148), Expect = 4e-09
Identities = 39/116 (33%), Positives = 58/116 (50%), Gaps = 2/116 (1%)
Frame = +2
Query: 83 GRDMPAI--GXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRT 256
GRD A G G + GV ++ + V A+ +G RH DTA+ Y E R
Sbjct: 15 GRDSAADADGSGVEMPMIGLGVFQTPPDETTAAVEEALRLGYRHIDTAAAYGNE----RE 70
Query: 257 VKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
V + + R+++FI TK+W + + E A + S KLG+D IDL L+H P+
Sbjct: 71 VGEGIRRAGIARDEVFIETKIWISDYGYDETLHAFDKSAGKLGVDQIDLLLLHQPL 126
Score = 39.9 bits (89), Expect = 0.058
Identities = 22/54 (40%), Positives = 32/54 (59%)
Frame = +1
Query: 445 SFGRRLHGDLARIGRCSANGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
+F R L G + + A+G ++ IG+SNF + L R+L E +I P QIEVH
Sbjct: 129 AFDRTL-GAYRALEKLLADGKVRAIGVSNFMPEHLTRLLTETSIVPAVNQIEVH 181
>UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona
intestinalis|Rep: Aldo-keto reductase 1a - Ciona
intestinalis (Transparent sea squirt)
Length = 584
Score = 63.7 bits (148), Expect = 4e-09
Identities = 48/168 (28%), Positives = 78/168 (46%), Gaps = 14/168 (8%)
Frame = +2
Query: 56 EVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVY-- 229
E+P +K+N+G MP IG GT F + + V A+ +G R DTA +Y
Sbjct: 256 EIPDVKLNSGYMMPPIGLGTARLFSKT----------YETVKTALKLGYRMLDTAQIYTG 305
Query: 230 ETETRNWRT-----VKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDY 394
E + N++ + + + V R ++FI TKL + + +SLKKL DY
Sbjct: 306 EDKINNFKVSSEEEIGRAIADSDVPRSELFIVTKLAPESMEKENAIAKVEESLKKLRTDY 365
Query: 395 IDLYLMHWPIGLNADYSHSDVDFME-------TWRGLEDAQRMGILKA 517
IDL L+H ++ D D E W+ +E+ Q G++++
Sbjct: 366 IDLLLIH-DFYMSTACGPDDTDLPECKNNPFLAWKTMEEMQAKGLVRS 412
>UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG05425;
n=1; Caenorhabditis briggsae|Rep: Putative
uncharacterized protein CBG05425 - Caenorhabditis
briggsae
Length = 319
Score = 63.3 bits (147), Expect = 5e-09
Identities = 37/117 (31%), Positives = 62/117 (52%), Gaps = 4/117 (3%)
Frame = +2
Query: 164 LRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRT 343
L V +A++VG R FDTA YE E +K+ + + + EDIF+TTK++ ++ +
Sbjct: 79 LLHAVDKAVEVGYRSFDTAKYYENEGELGEALKILLPKYKLSTEDIFLTTKIFPVENAAS 138
Query: 344 E--VAQAINDSLKKLGLDYIDLYLMHWPIGLNAD--YSHSDVDFMETWRGLEDAQRM 502
+ + I +SLK L +Y+DL L+H+P D + + E W LE + +
Sbjct: 139 GELIKKDIEESLKLLNREYLDLVLVHYPRPFTTDDKDERNKIYRKEAWLALESLKSL 195
>UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 253
Score = 63.3 bits (147), Expect = 5e-09
Identities = 41/113 (36%), Positives = 56/113 (49%)
Frame = +2
Query: 89 DMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETRNWRTVKMK 268
D+P +G GT +G + VV++ AID G RH DTA +Y+ E+ TV
Sbjct: 2 DLPPVGLGT-MGIEDEAVVRT-----------AIDCGYRHLDTAQIYDNES----TVGAG 45
Query: 269 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 427
+ R D+ + TKLW T V A SL +LGLD +DL +H P G
Sbjct: 46 IAAADTDRADLTVATKLWIDALEATAVRPATEASLDRLGLDAVDLLYVHRPRG 98
>UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 283
Score = 62.9 bits (146), Expect = 7e-09
Identities = 46/127 (36%), Positives = 65/127 (51%)
Frame = +2
Query: 47 STMEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASV 226
S E ++ + NG +P IG G ++ K + +V +A+D G RH DTA+V
Sbjct: 4 SQTESTTVTLTNGMVIPRIGFGAFM---------LKYNECYGLVTQALDSGYRHIDTAAV 54
Query: 227 YETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLY 406
Y E + + E+ VKR DIF+T+KL N + A AI SL LG YIDL+
Sbjct: 55 YGNEDICGKAIVDWCEKNNVKRTDIFLTSKLANCSDYYSTRA-AIRSSLHHLG-TYIDLF 112
Query: 407 LMHWPIG 427
L+ P G
Sbjct: 113 LIQSPAG 119
>UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 682
Score = 62.9 bits (146), Expect = 7e-09
Identities = 48/139 (34%), Positives = 70/139 (50%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
S ++N G +PA+G GT + G+V V A+ G RH DTA E
Sbjct: 413 SFRLNTGALIPAVGLGTRRA-QKPGLVYR-------AVRSALKTGYRHIDTAMSSGVE-- 462
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
+ V++ V R +++TTKL N H T V +A++ SL +LG+DY+DLYLM
Sbjct: 463 --HEIGQAVKDSGVSRSQVWVTTKLDNRWH--TRVQEALDMSLSELGMDYVDLYLM---- 514
Query: 425 GLNADYSHSDVDFMETWRG 481
+D DF++TW G
Sbjct: 515 -------LADWDFVKTWYG 526
>UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 286
Score = 62.5 bits (145), Expect = 9e-09
Identities = 46/151 (30%), Positives = 76/151 (50%)
Frame = +2
Query: 65 SLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETETR 244
S ++ NG +PAIG GT+ G D N ++++++V AI G RH D A+ Y E
Sbjct: 7 SFRLVNGSTLPAIGLGTFQGDDGN-------EKVKNIVKAAIQAGYRHIDGAAAYGNE-- 57
Query: 245 NWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 424
+ ++E + R+++ + W H +V +A++ SL+ LGL+Y+ + P
Sbjct: 58 --EAIGDAIKESGISRDEL---AQPW---HEPKDVERALDLSLEALGLEYVPHAYLPGP- 108
Query: 425 GLNADYSHSDVDFMETWRGLEDAQRMGILKA 517
N DY S + ETW+ +E G KA
Sbjct: 109 -NNVDYERSR-KYTETWQAMEKLVDSGKAKA 137
Score = 35.9 bits (79), Expect = 0.94
Identities = 16/36 (44%), Positives = 23/36 (63%)
Frame = +1
Query: 499 NGYIKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 606
+G K IGLSNFN + +R+L+ I+P Q+E H
Sbjct: 132 SGKAKAIGLSNFNILKTKRILEIARIRPAVNQVEAH 167
>UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Aldo/keto reductase -
Halorubrum lacusprofundi ATCC 49239
Length = 309
Score = 62.5 bits (145), Expect = 9e-09
Identities = 40/121 (33%), Positives = 61/121 (50%)
Frame = +2
Query: 59 VPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVYETE 238
+P+ + +G +PA+G GTY D D Q+ D V A+ G H DTA Y E
Sbjct: 34 IPTQTLPSGDTLPALGLGTY-ALD--------DDQIADSVRAALSSGYTHIDTAEGYHNE 84
Query: 239 TRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 418
+ + E R+D+F+T+K+ + Q+ SL++L DY+DLYL+HW
Sbjct: 85 ----EAIGEVLAE--YDRDDVFLTSKVLAKNLGYESLIQSCEASLERLETDYLDLYLIHW 138
Query: 419 P 421
P
Sbjct: 139 P 139
>UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1;
Phytophthora infestans|Rep: Aldo-keto reductase,
putative - Phytophthora infestans (Potato late blight
fungus)
Length = 255
Score = 62.1 bits (144), Expect = 1e-08
Identities = 44/155 (28%), Positives = 74/155 (47%)
Frame = +2
Query: 50 TMEVPSLKMNNGRDMPAIGXGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG*RHFDTASVY 229
++ VP+ + +G +P IG G Y + + ++ ++ +G RH DTA +Y
Sbjct: 2 SVNVPTKILPSGARIPMIGLGVYQS--------EPGPETYNAILTSLKLGYRHIDTAEIY 53
Query: 230 ETETRNWRTVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 409
E R V+ + + RE+IF+TTKL+ T ++ A S +LG+ YI LYL
Sbjct: 54 GNEEDVGRAVR----DSGIPREEIFVTTKLFTTNWGYSKALAAGKASNDRLGIVYIYLYL 109
Query: 410 MHWPIGLNADYSHSDVDFMETWRGLEDAQRMGILK 514
+H P + +TWR +ED + L+
Sbjct: 110 LHAP--------GPPKERADTWRAVEDLREQETLR 136
Score = 34.3 bits (75), Expect = 2.9
Identities = 16/44 (36%), Positives = 25/44 (56%)
Frame = +1
Query: 508 IKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHSKTFRKKWWNF 639
++ IG+SNFN+ L + K IKP Q+E+H R+ N+
Sbjct: 135 LRDIGVSNFNETLLATLRKTAHIKPAVNQVELHPWMMRQSLVNY 178
>UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 212
Score = 62.1 bits (144), Expect = 1e-08
Identities = 41/125 (32%), Positives = 65/125 (52%), Gaps = 9/125 (7%)
Frame = +2
Query: 170 DVVMRAIDVG*RHFDTASVYETETRNWRTVKMKVEEGVVK-REDIFITTKLWNTQHRRTE 346
D ++ AI++G RHFD + Y +E +K V+ G++K R+++FIT
Sbjct: 30 DSILTAIELGYRHFDCVAAYLSEKPLGEAIKKAVKLGLIKSRDELFITL----------- 78
Query: 347 VAQAINDSLKKLGLDYIDLYLMHWPIGLN-ADY-------SHSDVDFMETWRGLEDAQRM 502
QA+N L LDY+DLYL+HW + L +Y H +D W+ +ED Q++
Sbjct: 79 --QALN-----LQLDYLDLYLIHWSVSLKPGNYELPVNKDDHLPIDLGSVWKAMEDFQKL 131
Query: 503 GILKA 517
+ KA
Sbjct: 132 SLTKA 136
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 687,498,803
Number of Sequences: 1657284
Number of extensions: 13542437
Number of successful extensions: 38185
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 36251
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 37704
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 54545459628
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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