Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= e96h0878
(685 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AB066215-1|BAB83890.1| 392|Homo sapiens Apg4B protein. 118 3e-26
BC000719-1|AAH00719.1| 393|Homo sapiens ATG4 autophagy related ... 115 1e-25
AK125277-1|BAC86110.1| 468|Homo sapiens protein ( Homo sapiens ... 115 1e-25
AK027763-1|BAB55353.1| 380|Homo sapiens protein ( Homo sapiens ... 115 1e-25
AJ504652-1|CAD43219.1| 393|Homo sapiens autophagin-1 protein. 115 1e-25
AC133528-3|AAY14919.1| 393|Homo sapiens unknown protein. 115 1e-25
AB023160-1|BAA76787.2| 396|Homo sapiens KIAA0943 protein protein. 115 1e-25
BC061696-1|AAH61696.1| 398|Homo sapiens ATG4 autophagy related ... 106 6e-23
AL031177-11|CAI43138.1| 336|Homo sapiens ATG4 autophagy related... 106 6e-23
AL031177-10|CAI43137.1| 398|Homo sapiens ATG4 autophagy related... 106 6e-23
AJ504651-1|CAD43218.1| 398|Homo sapiens autophagin-2 protein. 106 6e-23
AJ320509-1|CAC69077.1| 336|Homo sapiens putative autophagy-rela... 106 6e-23
AJ320508-1|CAC69076.1| 398|Homo sapiens putative autophagy-rela... 106 6e-23
AB066214-1|BAB83889.1| 398|Homo sapiens Apg4A protein. 106 6e-23
AL031177-9|CAO03368.1| 231|Homo sapiens ATG4 autophagy related ... 95 2e-19
AK054927-1|BAB70829.1| 168|Homo sapiens protein ( Homo sapiens ... 95 2e-19
AL031177-14|CAI43141.1| 311|Homo sapiens ATG4 autophagy related... 75 2e-13
BC068992-1|AAH68992.1| 474|Homo sapiens ATG4 autophagy related ... 74 4e-13
AK223383-1|BAD97103.1| 474|Homo sapiens APG4 autophagy 4 homolo... 74 4e-13
AJ312332-1|CAC85951.1| 474|Homo sapiens APG4-D protein protein. 74 4e-13
BC033024-1|AAH33024.1| 458|Homo sapiens ATG4 autophagy related ... 63 1e-09
AK027773-1|BAB55356.1| 446|Homo sapiens protein ( Homo sapiens ... 63 1e-09
AJ320169-1|CAC43939.1| 458|Homo sapiens putative autophagy-rela... 63 1e-09
AJ312234-1|CAC85556.1| 458|Homo sapiens Apg4-C protein protein. 63 1e-09
BC018678-1|AAH18678.1| 451|Homo sapiens Unknown (protein for IM... 62 1e-09
BC041862-1|AAH41862.1| 321|Homo sapiens ATG4 autophagy related ... 49 1e-05
AL031177-15|CAI43142.1| 202|Homo sapiens ATG4 autophagy related... 49 1e-05
AK027462-1|BAB55127.1| 331|Homo sapiens protein ( Homo sapiens ... 47 5e-05
AK027332-1|BAB55042.1| 280|Homo sapiens r (MAFB) mRNA. protein. 47 5e-05
U96114-1|AAC51325.1| 870|Homo sapiens WWP2 protein. 30 6.7
BC064531-1|AAH64531.1| 870|Homo sapiens WWP2 protein protein. 30 6.7
BC013645-1|AAH13645.1| 870|Homo sapiens WW domain containing E3... 30 6.7
BC000108-1|AAH00108.1| 335|Homo sapiens WW domain containing E3... 30 6.7
>AB066215-1|BAB83890.1| 392|Homo sapiens Apg4B protein.
Length = 392
Score = 118 bits (283), Expect = 3e-26
Identities = 59/127 (46%), Positives = 72/127 (56%), Gaps = 1/127 (0%)
Frame = +3
Query: 258 PKTKESIWVLGKKYSAIQDLDRIRRDITSIIWCTYRKGFVPIGDEGLTSDKGWGCMLRCG 437
P+T E +W+LG+KYS + D I D+ S +W TYRK F IG G TSD GWGCMLRCG
Sbjct: 20 PETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPAIGGTGPTSDTGWGCMLRCG 79
Query: 438 QMVLGVALVRVHLSVDWVWSPETRIQLI*RSYQRLKKGNK-HLIPIHQVALMGCPLKEKK 614
QM+ ALV HL DW W+ R S K IHQ+A MG + EK
Sbjct: 80 QMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMG--VGEKS 137
Query: 615 LAQWFGP 635
+ QW+GP
Sbjct: 138 IGQWYGP 144
>BC000719-1|AAH00719.1| 393|Homo sapiens ATG4 autophagy related 4
homolog B (S. cerevisiae) protein.
Length = 393
Score = 115 bits (277), Expect = 1e-25
Identities = 58/127 (45%), Positives = 71/127 (55%), Gaps = 1/127 (0%)
Frame = +3
Query: 258 PKTKESIWVLGKKYSAIQDLDRIRRDITSIIWCTYRKGFVPIGDEGLTSDKGWGCMLRCG 437
P+T E +W+LG+KYS + D I D+ S +W TYRK F IG G TSD GWGCMLRCG
Sbjct: 20 PETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPAIGGTGPTSDTGWGCMLRCG 79
Query: 438 QMVLGVALVRVHLSVDWVWSPETRIQLI*RSYQRLKKGNK-HLIPIHQVALMGCPLKEKK 614
QM+ ALV HL DW W+ R S K IHQ+A MG + K
Sbjct: 80 QMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGVG-EGKS 138
Query: 615 LAQWFGP 635
+ QW+GP
Sbjct: 139 IGQWYGP 145
Score = 33.1 bits (72), Expect = 0.95
Identities = 23/64 (35%), Positives = 33/64 (51%), Gaps = 2/64 (3%)
Frame = +2
Query: 500 RNKDP-TYLKIIPKVEERKQAPYSYPSSGIDGVPSEGKEVGPVVWT*IQSL-QVLKKLTV 673
R + P +Y ++ +RK + YS GV EGK +G W ++ QVLKKL V
Sbjct: 101 RKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGV-GEGKSIGQ--WYGPNTVAQVLKKLAV 157
Query: 674 YDQW 685
+D W
Sbjct: 158 FDTW 161
>AK125277-1|BAC86110.1| 468|Homo sapiens protein ( Homo sapiens
cDNA FLJ43287 fis, clone MESAN2006563. ).
Length = 468
Score = 115 bits (277), Expect = 1e-25
Identities = 58/127 (45%), Positives = 71/127 (55%), Gaps = 1/127 (0%)
Frame = +3
Query: 258 PKTKESIWVLGKKYSAIQDLDRIRRDITSIIWCTYRKGFVPIGDEGLTSDKGWGCMLRCG 437
P+T E +W+LG+KYS + D I D+ S +W TYRK F IG G TSD GWGCMLRCG
Sbjct: 108 PETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPAIGGTGPTSDTGWGCMLRCG 167
Query: 438 QMVLGVALVRVHLSVDWVWSPETRIQLI*RSYQRLKKGNK-HLIPIHQVALMGCPLKEKK 614
QM+ ALV HL DW W+ R S K IHQ+A MG + K
Sbjct: 168 QMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGVG-EGKS 226
Query: 615 LAQWFGP 635
+ QW+GP
Sbjct: 227 IGQWYGP 233
Score = 33.1 bits (72), Expect = 0.95
Identities = 23/64 (35%), Positives = 33/64 (51%), Gaps = 2/64 (3%)
Frame = +2
Query: 500 RNKDP-TYLKIIPKVEERKQAPYSYPSSGIDGVPSEGKEVGPVVWT*IQSL-QVLKKLTV 673
R + P +Y ++ +RK + YS GV EGK +G W ++ QVLKKL V
Sbjct: 189 RKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGV-GEGKSIGQ--WYGPNTVAQVLKKLAV 245
Query: 674 YDQW 685
+D W
Sbjct: 246 FDTW 249
>AK027763-1|BAB55353.1| 380|Homo sapiens protein ( Homo sapiens
cDNA FLJ14857 fis, clone PLACE1001185. ).
Length = 380
Score = 115 bits (277), Expect = 1e-25
Identities = 58/127 (45%), Positives = 71/127 (55%), Gaps = 1/127 (0%)
Frame = +3
Query: 258 PKTKESIWVLGKKYSAIQDLDRIRRDITSIIWCTYRKGFVPIGDEGLTSDKGWGCMLRCG 437
P+T E +W+LG+KYS + D I D+ S +W TYRK F IG G TSD GWGCMLRCG
Sbjct: 20 PETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPAIGGTGPTSDTGWGCMLRCG 79
Query: 438 QMVLGVALVRVHLSVDWVWSPETRIQLI*RSYQRLKKGNK-HLIPIHQVALMGCPLKEKK 614
QM+ ALV HL DW W+ R S K IHQ+A MG + K
Sbjct: 80 QMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGVG-EGKS 138
Query: 615 LAQWFGP 635
+ QW+GP
Sbjct: 139 IGQWYGP 145
Score = 33.1 bits (72), Expect = 0.95
Identities = 23/64 (35%), Positives = 33/64 (51%), Gaps = 2/64 (3%)
Frame = +2
Query: 500 RNKDP-TYLKIIPKVEERKQAPYSYPSSGIDGVPSEGKEVGPVVWT*IQSL-QVLKKLTV 673
R + P +Y ++ +RK + YS GV EGK +G W ++ QVLKKL V
Sbjct: 101 RKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGV-GEGKSIGQ--WYGPNTVAQVLKKLAV 157
Query: 674 YDQW 685
+D W
Sbjct: 158 FDTW 161
>AJ504652-1|CAD43219.1| 393|Homo sapiens autophagin-1 protein.
Length = 393
Score = 115 bits (277), Expect = 1e-25
Identities = 58/127 (45%), Positives = 71/127 (55%), Gaps = 1/127 (0%)
Frame = +3
Query: 258 PKTKESIWVLGKKYSAIQDLDRIRRDITSIIWCTYRKGFVPIGDEGLTSDKGWGCMLRCG 437
P+T E +W+LG+KYS + D I D+ S +W TYRK F IG G TSD GWGCMLRCG
Sbjct: 20 PETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPAIGGTGPTSDTGWGCMLRCG 79
Query: 438 QMVLGVALVRVHLSVDWVWSPETRIQLI*RSYQRLKKGNK-HLIPIHQVALMGCPLKEKK 614
QM+ ALV HL DW W+ R S K IHQ+A MG + K
Sbjct: 80 QMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGVG-EGKS 138
Query: 615 LAQWFGP 635
+ QW+GP
Sbjct: 139 IGQWYGP 145
Score = 33.1 bits (72), Expect = 0.95
Identities = 23/64 (35%), Positives = 33/64 (51%), Gaps = 2/64 (3%)
Frame = +2
Query: 500 RNKDP-TYLKIIPKVEERKQAPYSYPSSGIDGVPSEGKEVGPVVWT*IQSL-QVLKKLTV 673
R + P +Y ++ +RK + YS GV EGK +G W ++ QVLKKL V
Sbjct: 101 RKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGV-GEGKSIGQ--WYGPNTVAQVLKKLAV 157
Query: 674 YDQW 685
+D W
Sbjct: 158 FDTW 161
>AC133528-3|AAY14919.1| 393|Homo sapiens unknown protein.
Length = 393
Score = 115 bits (277), Expect = 1e-25
Identities = 58/127 (45%), Positives = 71/127 (55%), Gaps = 1/127 (0%)
Frame = +3
Query: 258 PKTKESIWVLGKKYSAIQDLDRIRRDITSIIWCTYRKGFVPIGDEGLTSDKGWGCMLRCG 437
P+T E +W+LG+KYS + D I D+ S +W TYRK F IG G TSD GWGCMLRCG
Sbjct: 20 PETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPAIGGTGPTSDTGWGCMLRCG 79
Query: 438 QMVLGVALVRVHLSVDWVWSPETRIQLI*RSYQRLKKGNK-HLIPIHQVALMGCPLKEKK 614
QM+ ALV HL DW W+ R S K IHQ+A MG + K
Sbjct: 80 QMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGVG-EGKS 138
Query: 615 LAQWFGP 635
+ QW+GP
Sbjct: 139 IGQWYGP 145
Score = 33.1 bits (72), Expect = 0.95
Identities = 23/64 (35%), Positives = 33/64 (51%), Gaps = 2/64 (3%)
Frame = +2
Query: 500 RNKDP-TYLKIIPKVEERKQAPYSYPSSGIDGVPSEGKEVGPVVWT*IQSL-QVLKKLTV 673
R + P +Y ++ +RK + YS GV EGK +G W ++ QVLKKL V
Sbjct: 101 RKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGV-GEGKSIGQ--WYGPNTVAQVLKKLAV 157
Query: 674 YDQW 685
+D W
Sbjct: 158 FDTW 161
>AB023160-1|BAA76787.2| 396|Homo sapiens KIAA0943 protein protein.
Length = 396
Score = 115 bits (277), Expect = 1e-25
Identities = 58/127 (45%), Positives = 71/127 (55%), Gaps = 1/127 (0%)
Frame = +3
Query: 258 PKTKESIWVLGKKYSAIQDLDRIRRDITSIIWCTYRKGFVPIGDEGLTSDKGWGCMLRCG 437
P+T E +W+LG+KYS + D I D+ S +W TYRK F IG G TSD GWGCMLRCG
Sbjct: 23 PETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPAIGGTGPTSDTGWGCMLRCG 82
Query: 438 QMVLGVALVRVHLSVDWVWSPETRIQLI*RSYQRLKKGNK-HLIPIHQVALMGCPLKEKK 614
QM+ ALV HL DW W+ R S K IHQ+A MG + K
Sbjct: 83 QMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGVG-EGKS 141
Query: 615 LAQWFGP 635
+ QW+GP
Sbjct: 142 IGQWYGP 148
Score = 33.1 bits (72), Expect = 0.95
Identities = 23/64 (35%), Positives = 33/64 (51%), Gaps = 2/64 (3%)
Frame = +2
Query: 500 RNKDP-TYLKIIPKVEERKQAPYSYPSSGIDGVPSEGKEVGPVVWT*IQSL-QVLKKLTV 673
R + P +Y ++ +RK + YS GV EGK +G W ++ QVLKKL V
Sbjct: 104 RKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGV-GEGKSIGQ--WYGPNTVAQVLKKLAV 160
Query: 674 YDQW 685
+D W
Sbjct: 161 FDTW 164
>BC061696-1|AAH61696.1| 398|Homo sapiens ATG4 autophagy related 4
homolog A (S. cerevisiae) protein.
Length = 398
Score = 106 bits (255), Expect = 6e-23
Identities = 53/130 (40%), Positives = 75/130 (57%), Gaps = 4/130 (3%)
Frame = +3
Query: 258 PKTKESIWVLGKKYSAIQDLDRIRRDITSIIWCTYRKGFVPIGDEGLTSDKGWGCMLRCG 437
P T E +W+LGK++ + ++ DI++ +W TYR+ F PIG G +SD GWGCMLRCG
Sbjct: 23 PDTDELVWILGKQHLLKTEKSKLLSDISARLWFTYRRKFSPIGGTGPSSDAGWGCMLRCG 82
Query: 438 QMVLGVALVRVHLSVDWVWSPETRIQLI*RSYQRLKK----GNKHLIPIHQVALMGCPLK 605
QM+L AL+ HL DW W + + YQR+ + IHQ+A MG +
Sbjct: 83 QMMLAQALICRHLGRDWSWEKQKEQP---KEYQRILQCFLDRKDCCYSIHQMAQMGVG-E 138
Query: 606 EKKLAQWFGP 635
K + +WFGP
Sbjct: 139 GKSIGEWFGP 148
Score = 31.5 bits (68), Expect = 2.9
Identities = 21/57 (36%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Frame = +2
Query: 518 YLKIIPKVEERKQAPYSYPSSGIDGVPSEGKEVGPVVWT*IQSL-QVLKKLTVYDQW 685
Y +I+ +RK YS GV EGK +G W ++ QVLKKL ++D+W
Sbjct: 111 YQRILQCFLDRKDCCYSIHQMAQMGV-GEGKSIGE--WFGPNTVAQVLKKLALFDEW 164
>AL031177-11|CAI43138.1| 336|Homo sapiens ATG4 autophagy related 4
homolog A (S. cerevisiae) protein.
Length = 336
Score = 106 bits (255), Expect = 6e-23
Identities = 53/130 (40%), Positives = 75/130 (57%), Gaps = 4/130 (3%)
Frame = +3
Query: 258 PKTKESIWVLGKKYSAIQDLDRIRRDITSIIWCTYRKGFVPIGDEGLTSDKGWGCMLRCG 437
P T E +W+LGK++ + ++ DI++ +W TYR+ F PIG G +SD GWGCMLRCG
Sbjct: 23 PDTDELVWILGKQHLLKTEKSKLLSDISARLWFTYRRKFSPIGGTGPSSDAGWGCMLRCG 82
Query: 438 QMVLGVALVRVHLSVDWVWSPETRIQLI*RSYQRLKK----GNKHLIPIHQVALMGCPLK 605
QM+L AL+ HL DW W + + YQR+ + IHQ+A MG +
Sbjct: 83 QMMLAQALICRHLGRDWSWEKQKEQP---KEYQRILQCFLDRKDCCYSIHQMAQMGVG-E 138
Query: 606 EKKLAQWFGP 635
K + +WFGP
Sbjct: 139 GKSIGEWFGP 148
Score = 31.5 bits (68), Expect = 2.9
Identities = 21/57 (36%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Frame = +2
Query: 518 YLKIIPKVEERKQAPYSYPSSGIDGVPSEGKEVGPVVWT*IQSL-QVLKKLTVYDQW 685
Y +I+ +RK YS GV EGK +G W ++ QVLKKL ++D+W
Sbjct: 111 YQRILQCFLDRKDCCYSIHQMAQMGV-GEGKSIGE--WFGPNTVAQVLKKLALFDEW 164
>AL031177-10|CAI43137.1| 398|Homo sapiens ATG4 autophagy related 4
homolog A (S. cerevisiae) protein.
Length = 398
Score = 106 bits (255), Expect = 6e-23
Identities = 53/130 (40%), Positives = 75/130 (57%), Gaps = 4/130 (3%)
Frame = +3
Query: 258 PKTKESIWVLGKKYSAIQDLDRIRRDITSIIWCTYRKGFVPIGDEGLTSDKGWGCMLRCG 437
P T E +W+LGK++ + ++ DI++ +W TYR+ F PIG G +SD GWGCMLRCG
Sbjct: 23 PDTDELVWILGKQHLLKTEKSKLLSDISARLWFTYRRKFSPIGGTGPSSDAGWGCMLRCG 82
Query: 438 QMVLGVALVRVHLSVDWVWSPETRIQLI*RSYQRLKK----GNKHLIPIHQVALMGCPLK 605
QM+L AL+ HL DW W + + YQR+ + IHQ+A MG +
Sbjct: 83 QMMLAQALICRHLGRDWSWEKQKEQP---KEYQRILQCFLDRKDCCYSIHQMAQMGVG-E 138
Query: 606 EKKLAQWFGP 635
K + +WFGP
Sbjct: 139 GKSIGEWFGP 148
Score = 31.5 bits (68), Expect = 2.9
Identities = 21/57 (36%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Frame = +2
Query: 518 YLKIIPKVEERKQAPYSYPSSGIDGVPSEGKEVGPVVWT*IQSL-QVLKKLTVYDQW 685
Y +I+ +RK YS GV EGK +G W ++ QVLKKL ++D+W
Sbjct: 111 YQRILQCFLDRKDCCYSIHQMAQMGV-GEGKSIGE--WFGPNTVAQVLKKLALFDEW 164
>AJ504651-1|CAD43218.1| 398|Homo sapiens autophagin-2 protein.
Length = 398
Score = 106 bits (255), Expect = 6e-23
Identities = 53/130 (40%), Positives = 75/130 (57%), Gaps = 4/130 (3%)
Frame = +3
Query: 258 PKTKESIWVLGKKYSAIQDLDRIRRDITSIIWCTYRKGFVPIGDEGLTSDKGWGCMLRCG 437
P T E +W+LGK++ + ++ DI++ +W TYR+ F PIG G +SD GWGCMLRCG
Sbjct: 23 PDTDELVWILGKQHLLKTEKSKLLSDISARLWFTYRRKFSPIGGTGPSSDAGWGCMLRCG 82
Query: 438 QMVLGVALVRVHLSVDWVWSPETRIQLI*RSYQRLKK----GNKHLIPIHQVALMGCPLK 605
QM+L AL+ HL DW W + + YQR+ + IHQ+A MG +
Sbjct: 83 QMMLAQALICRHLGRDWSWEKQKEQP---KEYQRILQCFLDRKDCCYSIHQMAQMGVG-E 138
Query: 606 EKKLAQWFGP 635
K + +WFGP
Sbjct: 139 GKSIGEWFGP 148
Score = 31.5 bits (68), Expect = 2.9
Identities = 21/57 (36%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Frame = +2
Query: 518 YLKIIPKVEERKQAPYSYPSSGIDGVPSEGKEVGPVVWT*IQSL-QVLKKLTVYDQW 685
Y +I+ +RK YS GV EGK +G W ++ QVLKKL ++D+W
Sbjct: 111 YQRILQCFLDRKDCCYSIHQMAQMGV-GEGKSIGE--WFGPNTVAQVLKKLALFDEW 164
>AJ320509-1|CAC69077.1| 336|Homo sapiens putative autophagy-related
cysteine endopeptidase protein.
Length = 336
Score = 106 bits (255), Expect = 6e-23
Identities = 53/130 (40%), Positives = 75/130 (57%), Gaps = 4/130 (3%)
Frame = +3
Query: 258 PKTKESIWVLGKKYSAIQDLDRIRRDITSIIWCTYRKGFVPIGDEGLTSDKGWGCMLRCG 437
P T E +W+LGK++ + ++ DI++ +W TYR+ F PIG G +SD GWGCMLRCG
Sbjct: 23 PDTDELVWILGKQHLLKTEKSKLLSDISARLWFTYRRKFSPIGGTGPSSDAGWGCMLRCG 82
Query: 438 QMVLGVALVRVHLSVDWVWSPETRIQLI*RSYQRLKK----GNKHLIPIHQVALMGCPLK 605
QM+L AL+ HL DW W + + YQR+ + IHQ+A MG +
Sbjct: 83 QMMLAQALICRHLGRDWSWEKQKEQP---KEYQRILQCFLDRKDCCYSIHQMAQMGVG-E 138
Query: 606 EKKLAQWFGP 635
K + +WFGP
Sbjct: 139 GKSIGEWFGP 148
Score = 31.5 bits (68), Expect = 2.9
Identities = 21/57 (36%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Frame = +2
Query: 518 YLKIIPKVEERKQAPYSYPSSGIDGVPSEGKEVGPVVWT*IQSL-QVLKKLTVYDQW 685
Y +I+ +RK YS GV EGK +G W ++ QVLKKL ++D+W
Sbjct: 111 YQRILQCFLDRKDCCYSIHQMAQMGV-GEGKSIGE--WFGPNTVAQVLKKLALFDEW 164
>AJ320508-1|CAC69076.1| 398|Homo sapiens putative autophagy-related
cysteine endopeptidase protein.
Length = 398
Score = 106 bits (255), Expect = 6e-23
Identities = 53/130 (40%), Positives = 75/130 (57%), Gaps = 4/130 (3%)
Frame = +3
Query: 258 PKTKESIWVLGKKYSAIQDLDRIRRDITSIIWCTYRKGFVPIGDEGLTSDKGWGCMLRCG 437
P T E +W+LGK++ + ++ DI++ +W TYR+ F PIG G +SD GWGCMLRCG
Sbjct: 23 PDTDELVWILGKQHLLKTEKSKLLSDISARLWFTYRRKFSPIGGTGPSSDAGWGCMLRCG 82
Query: 438 QMVLGVALVRVHLSVDWVWSPETRIQLI*RSYQRLKK----GNKHLIPIHQVALMGCPLK 605
QM+L AL+ HL DW W + + YQR+ + IHQ+A MG +
Sbjct: 83 QMMLAQALICRHLGRDWSWEKQKEQP---KEYQRILQCFLDRKDCCYSIHQMAQMGVG-E 138
Query: 606 EKKLAQWFGP 635
K + +WFGP
Sbjct: 139 GKSIGEWFGP 148
Score = 31.5 bits (68), Expect = 2.9
Identities = 21/57 (36%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Frame = +2
Query: 518 YLKIIPKVEERKQAPYSYPSSGIDGVPSEGKEVGPVVWT*IQSL-QVLKKLTVYDQW 685
Y +I+ +RK YS GV EGK +G W ++ QVLKKL ++D+W
Sbjct: 111 YQRILQCFLDRKDCCYSIHQMAQMGV-GEGKSIGE--WFGPNTVAQVLKKLALFDEW 164
>AB066214-1|BAB83889.1| 398|Homo sapiens Apg4A protein.
Length = 398
Score = 106 bits (255), Expect = 6e-23
Identities = 53/130 (40%), Positives = 75/130 (57%), Gaps = 4/130 (3%)
Frame = +3
Query: 258 PKTKESIWVLGKKYSAIQDLDRIRRDITSIIWCTYRKGFVPIGDEGLTSDKGWGCMLRCG 437
P T E +W+LGK++ + ++ DI++ +W TYR+ F PIG G +SD GWGCMLRCG
Sbjct: 23 PDTDELVWILGKQHLLKTEKSKLLSDISARLWFTYRRKFSPIGGTGPSSDAGWGCMLRCG 82
Query: 438 QMVLGVALVRVHLSVDWVWSPETRIQLI*RSYQRLKK----GNKHLIPIHQVALMGCPLK 605
QM+L AL+ HL DW W + + YQR+ + IHQ+A MG +
Sbjct: 83 QMMLAQALICRHLGRDWSWEKQKEQP---KEYQRILQCFLDRKDCCYSIHQMAQMGVG-E 138
Query: 606 EKKLAQWFGP 635
K + +WFGP
Sbjct: 139 GKSIGEWFGP 148
Score = 31.5 bits (68), Expect = 2.9
Identities = 21/57 (36%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Frame = +2
Query: 518 YLKIIPKVEERKQAPYSYPSSGIDGVPSEGKEVGPVVWT*IQSL-QVLKKLTVYDQW 685
Y +I+ +RK YS GV EGK +G W ++ QVLKKL ++D+W
Sbjct: 111 YQRILQCFLDRKDCCYSIHQMAQMGV-GEGKSIGE--WFGPNTVAQVLKKLALFDEW 164
>AL031177-9|CAO03368.1| 231|Homo sapiens ATG4 autophagy related 4
homolog A (S. cerevisiae) protein.
Length = 231
Score = 95.5 bits (227), Expect = 2e-19
Identities = 42/95 (44%), Positives = 59/95 (62%)
Frame = +3
Query: 258 PKTKESIWVLGKKYSAIQDLDRIRRDITSIIWCTYRKGFVPIGDEGLTSDKGWGCMLRCG 437
P T E +W+LGK++ + ++ DI++ +W TYR+ F PIG G +SD GWGCMLRCG
Sbjct: 23 PDTDELVWILGKQHLLKTEKSKLLSDISARLWFTYRRKFSPIGGTGPSSDAGWGCMLRCG 82
Query: 438 QMVLGVALVRVHLSVDWVWSPETRIQLI*RSYQRL 542
QM+L AL+ HL DW W + + YQR+
Sbjct: 83 QMMLAQALICRHLGRDWSWEKQKEQP---KEYQRI 114
>AK054927-1|BAB70829.1| 168|Homo sapiens protein ( Homo sapiens
cDNA FLJ30365 fis, clone BRACE2007784, weakly similar to
Putative Protein that mediates attachment of
autophagosomes to ).
Length = 168
Score = 95.5 bits (227), Expect = 2e-19
Identities = 42/95 (44%), Positives = 59/95 (62%)
Frame = +3
Query: 258 PKTKESIWVLGKKYSAIQDLDRIRRDITSIIWCTYRKGFVPIGDEGLTSDKGWGCMLRCG 437
P T E +W+LGK++ + ++ DI++ +W TYR+ F PIG G +SD GWGCMLRCG
Sbjct: 23 PDTDELVWILGKQHLLKTEKSKLLSDISARLWFTYRRKFSPIGGTGPSSDAGWGCMLRCG 82
Query: 438 QMVLGVALVRVHLSVDWVWSPETRIQLI*RSYQRL 542
QM+L AL+ HL DW W + + YQR+
Sbjct: 83 QMMLAQALICRHLGRDWSWEKQKEQP---KEYQRI 114
>AL031177-14|CAI43141.1| 311|Homo sapiens ATG4 autophagy related 4
homolog A (S. cerevisiae) protein.
Length = 311
Score = 74.9 bits (176), Expect = 2e-13
Identities = 39/105 (37%), Positives = 55/105 (52%), Gaps = 4/105 (3%)
Frame = +3
Query: 333 DITSIIWCTYRKGFVPIGDEGLTSDKGWGCMLRCGQMVLGVALVRVHLSVDWVWSPETRI 512
D ++W ++ + G G +SD GWGCMLRCGQM+L AL+ HL DW W +
Sbjct: 20 DTDELVWILGKQHLLKTGGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWSWEKQKEQ 79
Query: 513 QLI*RSYQRLKK----GNKHLIPIHQVALMGCPLKEKKLAQWFGP 635
+ YQR+ + IHQ+A MG + K + +WFGP
Sbjct: 80 P---KEYQRILQCFLDRKDCCYSIHQMAQMGVG-EGKSIGEWFGP 120
Score = 31.5 bits (68), Expect = 2.9
Identities = 21/57 (36%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Frame = +2
Query: 518 YLKIIPKVEERKQAPYSYPSSGIDGVPSEGKEVGPVVWT*IQSL-QVLKKLTVYDQW 685
Y +I+ +RK YS GV EGK +G W ++ QVLKKL ++D+W
Sbjct: 83 YQRILQCFLDRKDCCYSIHQMAQMGV-GEGKSIGE--WFGPNTVAQVLKKLALFDEW 136
>BC068992-1|AAH68992.1| 474|Homo sapiens ATG4 autophagy related 4
homolog D (S. cerevisiae) protein.
Length = 474
Score = 74.1 bits (174), Expect = 4e-13
Identities = 35/77 (45%), Positives = 46/77 (59%), Gaps = 2/77 (2%)
Frame = +3
Query: 273 SIWVLGKKY--SAIQDLDRIRRDITSIIWCTYRKGFVPIGDEGLTSDKGWGCMLRCGQMV 446
SI + G++Y D+ R +RD S +W TYR+ F P+ LTSD GWGCMLR GQM+
Sbjct: 93 SIHLCGRRYRFEGEGDIQRFQRDFVSRLWLTYRRDFPPLPGGCLTSDCGWGCMLRSGQMM 152
Query: 447 LGVALVRVHLSVDWVWS 497
L L+ L DW W+
Sbjct: 153 LAQGLLLHFLPRDWTWA 169
>AK223383-1|BAD97103.1| 474|Homo sapiens APG4 autophagy 4 homolog D
variant protein.
Length = 474
Score = 74.1 bits (174), Expect = 4e-13
Identities = 35/77 (45%), Positives = 46/77 (59%), Gaps = 2/77 (2%)
Frame = +3
Query: 273 SIWVLGKKY--SAIQDLDRIRRDITSIIWCTYRKGFVPIGDEGLTSDKGWGCMLRCGQMV 446
SI + G++Y D+ R +RD S +W TYR+ F P+ LTSD GWGCMLR GQM+
Sbjct: 93 SIHLCGRRYRFEGEGDIQRFQRDFVSRLWLTYRRDFPPLPGGCLTSDCGWGCMLRSGQMM 152
Query: 447 LGVALVRVHLSVDWVWS 497
L L+ L DW W+
Sbjct: 153 LAQGLLLHFLPRDWTWA 169
>AJ312332-1|CAC85951.1| 474|Homo sapiens APG4-D protein protein.
Length = 474
Score = 74.1 bits (174), Expect = 4e-13
Identities = 35/77 (45%), Positives = 46/77 (59%), Gaps = 2/77 (2%)
Frame = +3
Query: 273 SIWVLGKKY--SAIQDLDRIRRDITSIIWCTYRKGFVPIGDEGLTSDKGWGCMLRCGQMV 446
SI + G++Y D+ R +RD S +W TYR+ F P+ LTSD GWGCMLR GQM+
Sbjct: 93 SIHLCGRRYRFEGEGDIQRFQRDFVSRLWLTYRRDFPPLPGGCLTSDCGWGCMLRSGQMM 152
Query: 447 LGVALVRVHLSVDWVWS 497
L L+ L DW W+
Sbjct: 153 LAQGLLLHFLPRDWTWA 169
>BC033024-1|AAH33024.1| 458|Homo sapiens ATG4 autophagy related 4
homolog C (S. cerevisiae) protein.
Length = 458
Score = 62.9 bits (146), Expect = 1e-09
Identities = 28/68 (41%), Positives = 37/68 (54%)
Frame = +3
Query: 312 DLDRIRRDITSIIWCTYRKGFVPIGDEGLTSDKGWGCMLRCGQMVLGVALVRVHLSVDWV 491
+++ R+D S IW TYR+ F I LT+D GWGC LR GQM+L L+ L W
Sbjct: 75 NVEEFRKDFISRIWLTYREEFPQIEGSALTTDCGWGCTLRTGQMLLAQGLILHFLGRAWT 134
Query: 492 WSPETRIQ 515
W I+
Sbjct: 135 WPDALNIE 142
>AK027773-1|BAB55356.1| 446|Homo sapiens protein ( Homo sapiens
cDNA FLJ14867 fis, clone PLACE1002319. ).
Length = 446
Score = 62.9 bits (146), Expect = 1e-09
Identities = 28/68 (41%), Positives = 37/68 (54%)
Frame = +3
Query: 312 DLDRIRRDITSIIWCTYRKGFVPIGDEGLTSDKGWGCMLRCGQMVLGVALVRVHLSVDWV 491
+++ R+D S IW TYR+ F I LT+D GWGC LR GQM+L L+ L W
Sbjct: 75 NVEEFRKDFISRIWLTYREEFPQIEGSALTTDCGWGCTLRTGQMLLAQGLILHFLGRAWT 134
Query: 492 WSPETRIQ 515
W I+
Sbjct: 135 WPDALNIE 142
>AJ320169-1|CAC43939.1| 458|Homo sapiens putative autophagy-related
cysteine endopeptidase protein.
Length = 458
Score = 62.9 bits (146), Expect = 1e-09
Identities = 28/68 (41%), Positives = 37/68 (54%)
Frame = +3
Query: 312 DLDRIRRDITSIIWCTYRKGFVPIGDEGLTSDKGWGCMLRCGQMVLGVALVRVHLSVDWV 491
+++ R+D S IW TYR+ F I LT+D GWGC LR GQM+L L+ L W
Sbjct: 75 NVEEFRKDFISRIWLTYREEFPQIEGSALTTDCGWGCTLRTGQMLLAQGLILHFLGRAWT 134
Query: 492 WSPETRIQ 515
W I+
Sbjct: 135 WPDALNIE 142
>AJ312234-1|CAC85556.1| 458|Homo sapiens Apg4-C protein protein.
Length = 458
Score = 62.9 bits (146), Expect = 1e-09
Identities = 28/68 (41%), Positives = 37/68 (54%)
Frame = +3
Query: 312 DLDRIRRDITSIIWCTYRKGFVPIGDEGLTSDKGWGCMLRCGQMVLGVALVRVHLSVDWV 491
+++ R+D S IW TYR+ F I LT+D GWGC LR GQM+L L+ L W
Sbjct: 75 NVEEFRKDFISRIWLTYREEFPQIEGSALTTDCGWGCTLRTGQMLLAQGLILHFLGRAWT 134
Query: 492 WSPETRIQ 515
W I+
Sbjct: 135 WPDALNIE 142
>BC018678-1|AAH18678.1| 451|Homo sapiens Unknown (protein for
IMAGE:4657137) protein.
Length = 451
Score = 62.5 bits (145), Expect = 1e-09
Identities = 28/67 (41%), Positives = 36/67 (53%)
Frame = +3
Query: 315 LDRIRRDITSIIWCTYRKGFVPIGDEGLTSDKGWGCMLRCGQMVLGVALVRVHLSVDWVW 494
++ R+D S IW TYR+ F I LT+D GWGC LR GQM+L L+ L W W
Sbjct: 76 VEEFRKDFISRIWLTYREEFPQIEGSALTTDCGWGCTLRTGQMLLAQGLILHFLGRAWTW 135
Query: 495 SPETRIQ 515
I+
Sbjct: 136 PDALNIE 142
>BC041862-1|AAH41862.1| 321|Homo sapiens ATG4 autophagy related 4
homolog A (S. cerevisiae) protein.
Length = 321
Score = 49.2 bits (112), Expect = 1e-05
Identities = 29/75 (38%), Positives = 39/75 (52%), Gaps = 4/75 (5%)
Frame = +3
Query: 423 MLRCGQMVLGVALVRVHLSVDWVWSPETRIQLI*RSYQRLKK----GNKHLIPIHQVALM 590
MLRCGQM+L AL+ HL DW W + + YQR+ + IHQ+A M
Sbjct: 1 MLRCGQMMLAQALICRHLGRDWSWEKQKEQP---KEYQRILQCFLDRKDCCYSIHQMAQM 57
Query: 591 GCPLKEKKLAQWFGP 635
G + K + +WFGP
Sbjct: 58 GVG-EGKSIGEWFGP 71
Score = 31.5 bits (68), Expect = 2.9
Identities = 21/57 (36%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Frame = +2
Query: 518 YLKIIPKVEERKQAPYSYPSSGIDGVPSEGKEVGPVVWT*IQSL-QVLKKLTVYDQW 685
Y +I+ +RK YS GV EGK +G W ++ QVLKKL ++D+W
Sbjct: 34 YQRILQCFLDRKDCCYSIHQMAQMGV-GEGKSIGE--WFGPNTVAQVLKKLALFDEW 87
>AL031177-15|CAI43142.1| 202|Homo sapiens ATG4 autophagy related 4
homolog A (S. cerevisiae) protein.
Length = 202
Score = 49.2 bits (112), Expect = 1e-05
Identities = 29/75 (38%), Positives = 39/75 (52%), Gaps = 4/75 (5%)
Frame = +3
Query: 423 MLRCGQMVLGVALVRVHLSVDWVWSPETRIQLI*RSYQRLKK----GNKHLIPIHQVALM 590
MLRCGQM+L AL+ HL DW W + + YQR+ + IHQ+A M
Sbjct: 1 MLRCGQMMLAQALICRHLGRDWSWEKQKEQP---KEYQRILQCFLDRKDCCYSIHQMAQM 57
Query: 591 GCPLKEKKLAQWFGP 635
G + K + +WFGP
Sbjct: 58 GVG-EGKSIGEWFGP 71
Score = 31.5 bits (68), Expect = 2.9
Identities = 21/57 (36%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Frame = +2
Query: 518 YLKIIPKVEERKQAPYSYPSSGIDGVPSEGKEVGPVVWT*IQSL-QVLKKLTVYDQW 685
Y +I+ +RK YS GV EGK +G W ++ QVLKKL ++D+W
Sbjct: 34 YQRILQCFLDRKDCCYSIHQMAQMGV-GEGKSIGE--WFGPNTVAQVLKKLALFDEW 87
>AK027462-1|BAB55127.1| 331|Homo sapiens protein ( Homo sapiens
cDNA FLJ14556 fis, clone NT2RM2001867. ).
Length = 331
Score = 47.2 bits (107), Expect = 5e-05
Identities = 29/72 (40%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Frame = +3
Query: 423 MLRCGQMVLGVALVRVHLSVDWVWSPETRIQLI*RSYQRLKKGNK-HLIPIHQVALMGCP 599
MLRCGQM+ ALV HL DW W+ R S K IHQ+A MG
Sbjct: 1 MLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGVG 60
Query: 600 LKEKKLAQWFGP 635
+ K + QW+GP
Sbjct: 61 -EGKSIGQWYGP 71
Score = 33.1 bits (72), Expect = 0.95
Identities = 23/64 (35%), Positives = 33/64 (51%), Gaps = 2/64 (3%)
Frame = +2
Query: 500 RNKDP-TYLKIIPKVEERKQAPYSYPSSGIDGVPSEGKEVGPVVWT*IQSL-QVLKKLTV 673
R + P +Y ++ +RK + YS GV EGK +G W ++ QVLKKL V
Sbjct: 27 RKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGV-GEGKSIGQ--WYGPNTVAQVLKKLAV 83
Query: 674 YDQW 685
+D W
Sbjct: 84 FDTW 87
>AK027332-1|BAB55042.1| 280|Homo sapiens r (MAFB) mRNA. protein.
Length = 280
Score = 47.2 bits (107), Expect = 5e-05
Identities = 29/72 (40%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Frame = +3
Query: 423 MLRCGQMVLGVALVRVHLSVDWVWSPETRIQLI*RSYQRLKKGNK-HLIPIHQVALMGCP 599
MLRCGQM+ ALV HL DW W+ R S K IHQ+A MG
Sbjct: 1 MLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGVG 60
Query: 600 LKEKKLAQWFGP 635
+ K + QW+GP
Sbjct: 61 -EGKSIGQWYGP 71
Score = 33.1 bits (72), Expect = 0.95
Identities = 23/64 (35%), Positives = 33/64 (51%), Gaps = 2/64 (3%)
Frame = +2
Query: 500 RNKDP-TYLKIIPKVEERKQAPYSYPSSGIDGVPSEGKEVGPVVWT*IQSL-QVLKKLTV 673
R + P +Y ++ +RK + YS GV EGK +G W ++ QVLKKL V
Sbjct: 27 RKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGV-GEGKSIGQ--WYGPNTVAQVLKKLAV 83
Query: 674 YDQW 685
+D W
Sbjct: 84 FDTW 87
>U96114-1|AAC51325.1| 870|Homo sapiens WWP2 protein.
Length = 870
Score = 30.3 bits (65), Expect = 6.7
Identities = 16/41 (39%), Positives = 22/41 (53%), Gaps = 3/41 (7%)
Frame = +2
Query: 506 KDPTYLKII---PKVEERKQAPYSYPSSGIDGVPSEGKEVG 619
K LK++ PKV R+ SY +DG+PSE K+ G
Sbjct: 17 KSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTG 57
>BC064531-1|AAH64531.1| 870|Homo sapiens WWP2 protein protein.
Length = 870
Score = 30.3 bits (65), Expect = 6.7
Identities = 16/41 (39%), Positives = 22/41 (53%), Gaps = 3/41 (7%)
Frame = +2
Query: 506 KDPTYLKII---PKVEERKQAPYSYPSSGIDGVPSEGKEVG 619
K LK++ PKV R+ SY +DG+PSE K+ G
Sbjct: 17 KSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTG 57
>BC013645-1|AAH13645.1| 870|Homo sapiens WW domain containing E3
ubiquitin protein ligase 2 protein.
Length = 870
Score = 30.3 bits (65), Expect = 6.7
Identities = 16/41 (39%), Positives = 22/41 (53%), Gaps = 3/41 (7%)
Frame = +2
Query: 506 KDPTYLKII---PKVEERKQAPYSYPSSGIDGVPSEGKEVG 619
K LK++ PKV R+ SY +DG+PSE K+ G
Sbjct: 17 KSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTG 57
>BC000108-1|AAH00108.1| 335|Homo sapiens WW domain containing E3
ubiquitin protein ligase 2 protein.
Length = 335
Score = 30.3 bits (65), Expect = 6.7
Identities = 16/41 (39%), Positives = 22/41 (53%), Gaps = 3/41 (7%)
Frame = +2
Query: 506 KDPTYLKII---PKVEERKQAPYSYPSSGIDGVPSEGKEVG 619
K LK++ PKV R+ SY +DG+PSE K+ G
Sbjct: 17 KSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTG 57
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 106,307,349
Number of Sequences: 237096
Number of extensions: 2428525
Number of successful extensions: 4242
Number of sequences better than 10.0: 33
Number of HSP's better than 10.0 without gapping: 4078
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4241
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7783251346
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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