Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= e96h0764
(629 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 96 1e-19
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 95 2e-19
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 95 2e-19
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 95 2e-19
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 95 2e-19
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 95 2e-19
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 95 2e-19
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 95 2e-19
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 95 2e-19
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 95 2e-19
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 95 2e-19
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 95 2e-19
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 95 2e-19
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 95 2e-19
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 95 2e-19
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 91 2e-18
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 91 2e-18
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 91 2e-18
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 91 2e-18
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 91 2e-18
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 89 2e-17
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 89 2e-17
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 88 3e-17
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 88 3e-17
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 88 3e-17
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 88 3e-17
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 88 3e-17
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 88 3e-17
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 88 3e-17
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 88 3e-17
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 88 3e-17
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 88 3e-17
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 88 3e-17
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 85 2e-16
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 84 3e-16
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 84 3e-16
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 84 3e-16
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 84 3e-16
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 84 3e-16
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 84 3e-16
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 84 3e-16
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 84 3e-16
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 84 3e-16
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 84 3e-16
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 84 3e-16
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 84 3e-16
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 84 3e-16
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 84 3e-16
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 84 3e-16
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 84 3e-16
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 84 3e-16
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 84 5e-16
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 84 5e-16
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 84 5e-16
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 84 5e-16
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 84 5e-16
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 84 5e-16
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 84 5e-16
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 84 5e-16
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 84 5e-16
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 84 5e-16
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 84 5e-16
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 83 8e-16
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 83 8e-16
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 83 8e-16
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 83 8e-16
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 83 8e-16
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 83 8e-16
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 83 8e-16
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 83 8e-16
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 81 2e-15
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 81 3e-15
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 81 3e-15
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 81 3e-15
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 81 3e-15
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 81 3e-15
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 81 3e-15
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 81 3e-15
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 81 4e-15
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 80 7e-15
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 72 1e-12
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 72 1e-12
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 72 1e-12
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 72 1e-12
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 70 8e-12
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 69 1e-11
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 69 1e-11
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 64 5e-10
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 64 5e-10
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 64 5e-10
AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto red... 50 9e-06
AK027341-1|BAB55047.1| 314|Homo sapiens protein ( Homo sapiens ... 33 0.83
AB058759-1|BAB47485.1| 1134|Homo sapiens KIAA1856 protein protein. 33 0.83
U72619-1|AAB61992.1| 22|Homo sapiens aldose reductase protein. 31 3.4
U60819-1|AAB39829.1| 685|Homo sapiens rBAT protein. 31 4.5
M95548-1|AAA35500.1| 685|Homo sapiens amino acid transport prot... 31 4.5
L11696-1|AAA81778.1| 685|Homo sapiens amino acid transport rela... 31 4.5
D87076-1|BAA13245.2| 849|Homo sapiens KIAA0239 protein. 31 4.5
D82326-1|BAA11541.1| 685|Homo sapiens Na+-independent neutral a... 31 4.5
DQ023517-1|AAY89648.1| 551|Homo sapiens SLC3A1 variant G protein. 31 4.5
DQ023516-1|AAY89647.1| 564|Homo sapiens SLC3A1 variant F protein. 31 4.5
DQ023515-1|AAY89646.1| 502|Homo sapiens SLC3A1 variant E protein. 31 4.5
DQ023513-1|AAY89644.1| 391|Homo sapiens SLC3A1 variant C protein. 31 4.5
BC093626-1|AAH93626.1| 685|Homo sapiens solute carrier family 3... 31 4.5
BC093624-1|AAH93624.1| 685|Homo sapiens solute carrier family 3... 31 4.5
BC022386-1|AAH22386.1| 685|Homo sapiens solute carrier family 3... 31 4.5
BC021962-1|AAH21962.2| 791|Homo sapiens PHF15 protein protein. 31 4.5
BC009307-1|AAH09307.2| 574|Homo sapiens PHF15 protein protein. 31 4.5
BC004292-1|AAH04292.1| 246|Homo sapiens PHF15 protein protein. 31 4.5
AK223146-1|BAD96866.1| 685|Homo sapiens solute carrier family 3... 31 4.5
AJ317974-1|CAC38072.3| 1044|Homo sapiens ataxin-2 related domain... 31 4.5
AJ251833-1|CAB94935.1| 576|Homo sapiens hypothetical protein pr... 31 4.5
AC013717-2|AAX88955.1| 685|Homo sapiens unknown protein. 31 4.5
AB033549-1|BAB16841.1| 685|Homo sapiens hrBAT protein. 31 4.5
BC051787-1|AAH51787.1| 1375|Homo sapiens NLRP1 protein protein. 30 7.8
BC020956-1|AAH20956.1| 924|Homo sapiens SETD5 protein protein. 30 7.8
AK025478-1|BAB15144.1| 603|Homo sapiens protein ( Homo sapiens ... 30 7.8
AK001569-1|BAA91762.1| 924|Homo sapiens protein ( Homo sapiens ... 30 7.8
AF310105-1|AAG30288.1| 1429|Homo sapiens NALP1 protein. 30 7.8
AF298548-1|AAG15254.1| 1429|Homo sapiens caspase recruitment dom... 30 7.8
AF229062-1|AAK00751.1| 1443|Homo sapiens NAC-delta splice varian... 30 7.8
AF229061-1|AAK00750.1| 1399|Homo sapiens NAC-gamma splice varian... 30 7.8
AF229060-1|AAK00749.1| 1473|Homo sapiens NAC-beta splice variant... 30 7.8
AF229059-1|AAK00748.1| 1429|Homo sapiens NAC-alpha splice varian... 30 7.8
AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde redu... 30 7.8
AB051544-1|BAB21848.1| 1409|Homo sapiens KIAA1757 protein protein. 30 7.8
AB023143-1|BAA76770.2| 1447|Homo sapiens KIAA0926 protein protein. 30 7.8
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 95.9 bits (228), Expect = 1e-19
Identities = 38/61 (62%), Positives = 49/61 (80%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 245
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 ILLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 246 E 248
E
Sbjct: 65 E 65
Score = 83.4 bits (197), Expect = 6e-16
Identities = 34/69 (49%), Positives = 49/69 (71%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G ++ ++ + +KRE++FI SKLWCT+H LV+ A + +L +L L+YLDLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 398 FKEGDDLFP 424
FK G + FP
Sbjct: 116 FKPGKEFFP 124
Score = 44.0 bits (99), Expect = 4e-04
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Frame = +1
Query: 394 GLQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV- 570
G + G+ P D +PS + +DTW A+E LV++G Q+E +L
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 571 -AKIKPAVLQIEVAP 612
K KPAV QIE P
Sbjct: 175 GLKYKPAVNQIECHP 189
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 95.1 bits (226), Expect = 2e-19
Identities = 38/61 (62%), Positives = 49/61 (80%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 245
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 246 E 248
E
Sbjct: 65 E 65
Score = 83.4 bits (197), Expect = 6e-16
Identities = 34/69 (49%), Positives = 49/69 (71%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G ++ ++ + +KRE++FI SKLWCT+H LV+ A + +L +L L+YLDLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 398 FKEGDDLFP 424
FK G + FP
Sbjct: 116 FKPGKEFFP 124
Score = 44.0 bits (99), Expect = 4e-04
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Frame = +1
Query: 394 GLQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV- 570
G + G+ P D +PS + +DTW A+E LV++G Q+E +L
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 571 -AKIKPAVLQIEVAP 612
K KPAV QIE P
Sbjct: 175 GLKYKPAVNQIECHP 189
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 95.1 bits (226), Expect = 2e-19
Identities = 38/61 (62%), Positives = 49/61 (80%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 245
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 246 E 248
E
Sbjct: 65 E 65
Score = 83.4 bits (197), Expect = 6e-16
Identities = 34/69 (49%), Positives = 49/69 (71%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G ++ ++ + +KRE++FI SKLWCT+H LV+ A + +L +L L+YLDLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 398 FKEGDDLFP 424
FK G + FP
Sbjct: 116 FKPGKEFFP 124
Score = 44.0 bits (99), Expect = 4e-04
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Frame = +1
Query: 394 GLQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV- 570
G + G+ P D +PS + +DTW A+E LV++G Q+E +L
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 571 -AKIKPAVLQIEVAP 612
K KPAV QIE P
Sbjct: 175 GLKYKPAVNQIECHP 189
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 95.1 bits (226), Expect = 2e-19
Identities = 38/61 (62%), Positives = 49/61 (80%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 245
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 246 E 248
E
Sbjct: 65 E 65
Score = 83.4 bits (197), Expect = 6e-16
Identities = 34/69 (49%), Positives = 49/69 (71%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G ++ ++ + +KRE++FI SKLWCT+H LV+ A + +L +L L+YLDLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 398 FKEGDDLFP 424
FK G + FP
Sbjct: 116 FKPGKEFFP 124
Score = 44.0 bits (99), Expect = 4e-04
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Frame = +1
Query: 394 GLQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV- 570
G + G+ P D +PS + +DTW A+E LV++G Q+E +L
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 571 -AKIKPAVLQIEVAP 612
K KPAV QIE P
Sbjct: 175 GLKYKPAVNQIECHP 189
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 95.1 bits (226), Expect = 2e-19
Identities = 38/61 (62%), Positives = 49/61 (80%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 245
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 246 E 248
E
Sbjct: 65 E 65
Score = 83.4 bits (197), Expect = 6e-16
Identities = 34/69 (49%), Positives = 49/69 (71%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G ++ ++ + +KRE++FI SKLWCT+H LV+ A + +L +L L+YLDLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 398 FKEGDDLFP 424
FK G + FP
Sbjct: 116 FKPGKEFFP 124
Score = 44.0 bits (99), Expect = 4e-04
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Frame = +1
Query: 394 GLQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV- 570
G + G+ P D +PS + +DTW A+E LV++G Q+E +L
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 571 -AKIKPAVLQIEVAP 612
K KPAV QIE P
Sbjct: 175 GLKYKPAVNQIECHP 189
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 95.1 bits (226), Expect = 2e-19
Identities = 38/61 (62%), Positives = 49/61 (80%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 245
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 246 E 248
E
Sbjct: 65 E 65
Score = 83.4 bits (197), Expect = 6e-16
Identities = 34/69 (49%), Positives = 49/69 (71%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G ++ ++ + +KRE++FI SKLWCT+H LV+ A + +L +L L+YLDLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 398 FKEGDDLFP 424
FK G + FP
Sbjct: 116 FKPGKEFFP 124
Score = 44.0 bits (99), Expect = 4e-04
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Frame = +1
Query: 394 GLQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV- 570
G + G+ P D +PS + +DTW A+E LV++G Q+E +L
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 571 -AKIKPAVLQIEVAP 612
K KPAV QIE P
Sbjct: 175 GLKYKPAVNQIECHP 189
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 95.1 bits (226), Expect = 2e-19
Identities = 38/61 (62%), Positives = 49/61 (80%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 245
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 246 E 248
E
Sbjct: 65 E 65
Score = 82.6 bits (195), Expect = 1e-15
Identities = 34/69 (49%), Positives = 49/69 (71%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G ++ ++ + +KRE++FI SKLWCT+H LV+ A + +L +L L+YLDLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPIG 115
Query: 398 FKEGDDLFP 424
FK G + FP
Sbjct: 116 FKPGKEFFP 124
Score = 44.0 bits (99), Expect = 4e-04
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Frame = +1
Query: 394 GLQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV- 570
G + G+ P D +PS + +DTW A+E LV++G Q+E +L
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 571 -AKIKPAVLQIEVAP 612
K KPAV QIE P
Sbjct: 175 GLKYKPAVNQIECHP 189
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 95.1 bits (226), Expect = 2e-19
Identities = 38/61 (62%), Positives = 49/61 (80%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 245
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 246 E 248
E
Sbjct: 65 E 65
Score = 82.2 bits (194), Expect = 1e-15
Identities = 33/69 (47%), Positives = 49/69 (71%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G ++ ++ + +KRE++FI SKLWCT+H LV+ A + +L +L L+YLDLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 398 FKEGDDLFP 424
F+ G + FP
Sbjct: 116 FRPGKEFFP 124
Score = 44.0 bits (99), Expect = 4e-04
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Frame = +1
Query: 394 GLQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV- 570
G + G+ P D +PS + +DTW A+E LV++G Q+E +L
Sbjct: 115 GFRPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILSKP 174
Query: 571 -AKIKPAVLQIEVAP 612
K KPAV QIE P
Sbjct: 175 GLKYKPAVNQIECHP 189
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 95.1 bits (226), Expect = 2e-19
Identities = 38/61 (62%), Positives = 49/61 (80%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 245
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 246 E 248
E
Sbjct: 65 E 65
Score = 83.4 bits (197), Expect = 6e-16
Identities = 34/69 (49%), Positives = 49/69 (71%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G ++ ++ + +KRE++FI SKLWCT+H LV+ A + +L +L L+YLDLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 398 FKEGDDLFP 424
FK G + FP
Sbjct: 116 FKPGKEFFP 124
Score = 44.0 bits (99), Expect = 4e-04
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Frame = +1
Query: 394 GLQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV- 570
G + G+ P D +PS + +DTW A+E LV++G Q+E +L
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 571 -AKIKPAVLQIEVAP 612
K KPAV QIE P
Sbjct: 175 GLKYKPAVNQIECHP 189
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 95.1 bits (226), Expect = 2e-19
Identities = 38/61 (62%), Positives = 49/61 (80%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 245
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 246 E 248
E
Sbjct: 65 E 65
Score = 83.4 bits (197), Expect = 6e-16
Identities = 34/69 (49%), Positives = 49/69 (71%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G ++ ++ + +KRE++FI SKLWCT+H LV+ A + +L +L L+YLDLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 398 FKEGDDLFP 424
FK G + FP
Sbjct: 116 FKPGKEFFP 124
Score = 44.0 bits (99), Expect = 4e-04
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Frame = +1
Query: 394 GLQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV- 570
G + G+ P D +PS + +DTW A+E LV++G Q+E +L
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 571 -AKIKPAVLQIEVAP 612
K KPAV QIE P
Sbjct: 175 GLKYKPAVNQIECHP 189
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 95.1 bits (226), Expect = 2e-19
Identities = 38/61 (62%), Positives = 49/61 (80%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 245
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 246 E 248
E
Sbjct: 65 E 65
Score = 83.4 bits (197), Expect = 6e-16
Identities = 34/69 (49%), Positives = 49/69 (71%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G ++ ++ + +KRE++FI SKLWCT+H LV+ A + +L +L L+YLDLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 398 FKEGDDLFP 424
FK G + FP
Sbjct: 116 FKPGKEFFP 124
Score = 38.3 bits (85), Expect = 0.022
Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 2/75 (2%)
Frame = +1
Query: 394 GLQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV- 570
G + G+ P D +PS + +DT A+E LV++G Q+E +L
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTRAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 571 -AKIKPAVLQIEVAP 612
K KPAV QIE P
Sbjct: 175 GLKYKPAVNQIECHP 189
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 95.1 bits (226), Expect = 2e-19
Identities = 38/61 (62%), Positives = 49/61 (80%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 245
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 246 E 248
E
Sbjct: 65 E 65
Score = 83.4 bits (197), Expect = 6e-16
Identities = 34/69 (49%), Positives = 49/69 (71%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G ++ ++ + +KRE++FI SKLWCT+H LV+ A + +L +L L+YLDLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 398 FKEGDDLFP 424
FK G + FP
Sbjct: 116 FKPGKEFFP 124
Score = 44.0 bits (99), Expect = 4e-04
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Frame = +1
Query: 394 GLQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV- 570
G + G+ P D +PS + +DTW A+E LV++G Q+E +L
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 571 -AKIKPAVLQIEVAP 612
K KPAV QIE P
Sbjct: 175 GLKYKPAVNQIECHP 189
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 95.1 bits (226), Expect = 2e-19
Identities = 38/61 (62%), Positives = 49/61 (80%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 245
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 246 E 248
E
Sbjct: 65 E 65
Score = 83.4 bits (197), Expect = 6e-16
Identities = 34/69 (49%), Positives = 49/69 (71%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G ++ ++ + +KRE++FI SKLWCT+H LV+ A + +L +L L+YLDLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 398 FKEGDDLFP 424
FK G + FP
Sbjct: 116 FKPGKEFFP 124
Score = 44.0 bits (99), Expect = 4e-04
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Frame = +1
Query: 394 GLQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV- 570
G + G+ P D +PS + +DTW A+E LV++G Q+E +L
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 571 -AKIKPAVLQIEVAP 612
K KPAV QIE P
Sbjct: 175 GLKYKPAVNQIECHP 189
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 95.1 bits (226), Expect = 2e-19
Identities = 38/61 (62%), Positives = 49/61 (80%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 245
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 246 E 248
E
Sbjct: 65 E 65
Score = 83.4 bits (197), Expect = 6e-16
Identities = 34/69 (49%), Positives = 49/69 (71%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G ++ ++ + +KRE++FI SKLWCT+H LV+ A + +L +L L+YLDLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 398 FKEGDDLFP 424
FK G + FP
Sbjct: 116 FKPGKEFFP 124
Score = 44.0 bits (99), Expect = 4e-04
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Frame = +1
Query: 394 GLQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV- 570
G + G+ P D +PS + +DTW A+E LV++G Q+E +L
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 571 -AKIKPAVLQIEVAP 612
K KPAV QIE P
Sbjct: 175 GLKYKPAVNQIECHP 189
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 95.1 bits (226), Expect = 2e-19
Identities = 38/61 (62%), Positives = 49/61 (80%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 245
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 2 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 61
Query: 246 E 248
E
Sbjct: 62 E 62
Score = 83.4 bits (197), Expect = 6e-16
Identities = 34/69 (49%), Positives = 49/69 (71%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G ++ ++ + +KRE++FI SKLWCT+H LV+ A + +L +L L+YLDLYLIHWP
Sbjct: 53 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 112
Query: 398 FKEGDDLFP 424
FK G + FP
Sbjct: 113 FKPGKEFFP 121
Score = 44.0 bits (99), Expect = 4e-04
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Frame = +1
Query: 394 GLQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV- 570
G + G+ P D +PS + +DTW A+E LV++G Q+E +L
Sbjct: 112 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 171
Query: 571 -AKIKPAVLQIEVAP 612
K KPAV QIE P
Sbjct: 172 GLKYKPAVNQIECHP 186
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 91.5 bits (217), Expect = 2e-18
Identities = 39/70 (55%), Positives = 51/70 (72%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G ++ ++ + +KRED+FI SKLW TF LV +A + +LK+L L YLD+YLIHWPQ
Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115
Query: 398 FKEGDDLFPK 427
FK GDDLFPK
Sbjct: 116 FKSGDDLFPK 125
Score = 79.8 bits (188), Expect = 7e-15
Identities = 32/52 (61%), Positives = 43/52 (82%)
Frame = +3
Query: 93 PVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEE 248
P++GLGTWKS G+V +AVK AID GYRH+DCA++Y NE EVG+A++ K +E
Sbjct: 14 PIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQE 65
Score = 35.1 bits (77), Expect = 0.21
Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Frame = +1
Query: 394 GLQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV- 570
G + G P+D + I ++D W A+E LV++G + QIE++L
Sbjct: 115 GFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKP 174
Query: 571 -AKIKPAVLQIEVAP 612
K KP Q+E P
Sbjct: 175 GLKYKPVTNQVECHP 189
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 91.5 bits (217), Expect = 2e-18
Identities = 39/70 (55%), Positives = 51/70 (72%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G ++ ++ + +KRED+FI SKLW TF LV +A + +LK+L L YLD+YLIHWPQ
Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115
Query: 398 FKEGDDLFPK 427
FK GDDLFPK
Sbjct: 116 FKSGDDLFPK 125
Score = 79.8 bits (188), Expect = 7e-15
Identities = 32/52 (61%), Positives = 43/52 (82%)
Frame = +3
Query: 93 PVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEE 248
P++GLGTWKS G+V +AVK AID GYRH+DCA++Y NE EVG+A++ K +E
Sbjct: 14 PIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQE 65
Score = 35.1 bits (77), Expect = 0.21
Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Frame = +1
Query: 394 GLQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV- 570
G + G P+D + I ++D W A+E LV++G + QIE++L
Sbjct: 115 GFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKP 174
Query: 571 -AKIKPAVLQIEVAP 612
K KP Q+E P
Sbjct: 175 GLKYKPVTNQVECHP 189
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 91.5 bits (217), Expect = 2e-18
Identities = 39/70 (55%), Positives = 51/70 (72%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G ++ ++ + +KRED+FI SKLW TF LV +A + +LK+L L YLD+YLIHWPQ
Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115
Query: 398 FKEGDDLFPK 427
FK GDDLFPK
Sbjct: 116 FKSGDDLFPK 125
Score = 79.8 bits (188), Expect = 7e-15
Identities = 32/52 (61%), Positives = 43/52 (82%)
Frame = +3
Query: 93 PVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEE 248
P++GLGTWKS G+V +AVK AID GYRH+DCA++Y NE EVG+A++ K +E
Sbjct: 14 PIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQE 65
Score = 35.1 bits (77), Expect = 0.21
Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Frame = +1
Query: 394 GLQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV- 570
G + G P+D + I ++D W A+E LV++G + QIE++L
Sbjct: 115 GFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKP 174
Query: 571 -AKIKPAVLQIEVAP 612
K KP Q+E P
Sbjct: 175 GLKYKPVTNQVECHP 189
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 91.5 bits (217), Expect = 2e-18
Identities = 39/70 (55%), Positives = 51/70 (72%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G ++ ++ + +KRED+FI SKLW TF LV +A + +LK+L L YLD+YLIHWPQ
Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115
Query: 398 FKEGDDLFPK 427
FK GDDLFPK
Sbjct: 116 FKSGDDLFPK 125
Score = 79.8 bits (188), Expect = 7e-15
Identities = 32/52 (61%), Positives = 43/52 (82%)
Frame = +3
Query: 93 PVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEE 248
P++GLGTWKS G+V +AVK AID GYRH+DCA++Y NE EVG+A++ K +E
Sbjct: 14 PIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQE 65
Score = 35.1 bits (77), Expect = 0.21
Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Frame = +1
Query: 394 GLQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV- 570
G + G P+D + I ++D W A+E LV++G + QIE++L
Sbjct: 115 GFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKP 174
Query: 571 -AKIKPAVLQIEVAP 612
K KP Q+E P
Sbjct: 175 GLKYKPVTNQVECHP 189
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 91.5 bits (217), Expect = 2e-18
Identities = 39/70 (55%), Positives = 51/70 (72%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G ++ ++ + +KRED+FI SKLW TF LV +A + +LK+L L YLD+YLIHWPQ
Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115
Query: 398 FKEGDDLFPK 427
FK GDDLFPK
Sbjct: 116 FKSGDDLFPK 125
Score = 79.8 bits (188), Expect = 7e-15
Identities = 32/52 (61%), Positives = 43/52 (82%)
Frame = +3
Query: 93 PVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEE 248
P++GLGTWKS G+V +AVK AID GYRH+DCA++Y NE EVG+A++ K +E
Sbjct: 14 PIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQE 65
Score = 35.1 bits (77), Expect = 0.21
Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Frame = +1
Query: 394 GLQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV- 570
G + G P+D + I ++D W A+E LV++G + QIE++L
Sbjct: 115 GFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKP 174
Query: 571 -AKIKPAVLQIEVAP 612
K KP Q+E P
Sbjct: 175 GLKYKPVTNQVECHP 189
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 88.6 bits (210), Expect = 2e-17
Identities = 42/90 (46%), Positives = 59/90 (65%)
Frame = +2
Query: 158 DRYRLPARGLRPHLPQ*EGGGGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKT 337
D + +P G + P G + S++ +KREDIF TSKLWC HRP+LV A++
Sbjct: 10 DGHFMPVLGFGTYAPAEVGLA--IRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALER 67
Query: 338 SLKNLGLEYLDLYLIHWPQAFKEGDDLFPK 427
SLKNL L+Y+DLYLIH+P + K G+++ PK
Sbjct: 68 SLKNLQLDYVDLYLIHFPVSVKPGEEVIPK 97
Score = 33.9 bits (74), Expect = 0.48
Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 2/71 (2%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKI 579
G +P+D K + VD TW A+E + G RQ+E +L K
Sbjct: 91 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 150
Query: 580 KPAVLQIEVAP 612
KP Q+E P
Sbjct: 151 KPVCNQVECHP 161
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 88.6 bits (210), Expect = 2e-17
Identities = 38/70 (54%), Positives = 50/70 (71%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G ++ ++ + +KRED+FI SKLW TF LV +A + +LK+ L YLD+YLIHWPQ
Sbjct: 56 GEAIQEKIQEKAVKREDLFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQG 115
Query: 398 FKEGDDLFPK 427
FK GDDLFPK
Sbjct: 116 FKSGDDLFPK 125
Score = 79.8 bits (188), Expect = 7e-15
Identities = 32/52 (61%), Positives = 43/52 (82%)
Frame = +3
Query: 93 PVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEE 248
P++GLGTWKS G+V +AVK AID GYRH+DCA++Y NE EVG+A++ K +E
Sbjct: 14 PIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQE 65
Score = 35.1 bits (77), Expect = 0.21
Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Frame = +1
Query: 394 GLQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV- 570
G + G P+D + I ++D W A+E LV++G + QIE++L
Sbjct: 115 GFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKP 174
Query: 571 -AKIKPAVLQIEVAP 612
K KP Q+E P
Sbjct: 175 GLKYKPVTNQVECHP 189
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 87.8 bits (208), Expect = 3e-17
Identities = 38/70 (54%), Positives = 52/70 (74%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLWC HRP+LV A++ SLKNL L+Y+DLYLIH+P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 398 FKEGDDLFPK 427
K G+++ PK
Sbjct: 122 VKPGEEVIPK 131
Score = 58.8 bits (136), Expect = 1e-08
Identities = 31/70 (44%), Positives = 44/70 (62%), Gaps = 5/70 (7%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 230
V N+G PV+G GT+ P EV +A K AI+ G+RH+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 231 RAKFEEGKSK 260
R+K +G K
Sbjct: 66 RSKIADGSVK 75
Score = 33.9 bits (74), Expect = 0.48
Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 2/71 (2%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKI 579
G +P+D K + VD TW A+E + G RQ+E +L K
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 580 KPAVLQIEVAP 612
KP Q+E P
Sbjct: 185 KPVCNQVECHP 195
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 87.8 bits (208), Expect = 3e-17
Identities = 38/70 (54%), Positives = 52/70 (74%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLWC HRP+LV A++ SLKNL L+Y+DLYLIH+P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 398 FKEGDDLFPK 427
K G+++ PK
Sbjct: 122 VKPGEEVIPK 131
Score = 58.8 bits (136), Expect = 1e-08
Identities = 31/70 (44%), Positives = 44/70 (62%), Gaps = 5/70 (7%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 230
V N+G PV+G GT+ P EV +A K AI+ G+RH+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 231 RAKFEEGKSK 260
R+K +G K
Sbjct: 66 RSKIADGSVK 75
Score = 33.9 bits (74), Expect = 0.48
Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 2/71 (2%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKI 579
G +P+D K + VD TW A+E + G RQ+E +L K
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 580 KPAVLQIEVAP 612
KP Q+E P
Sbjct: 185 KPVCNQVECHP 195
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 87.8 bits (208), Expect = 3e-17
Identities = 38/70 (54%), Positives = 52/70 (74%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLWC HRP+LV A++ SLKNL L+Y+DLYLIH+P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 398 FKEGDDLFPK 427
K G+++ PK
Sbjct: 122 VKPGEEVIPK 131
Score = 58.8 bits (136), Expect = 1e-08
Identities = 31/70 (44%), Positives = 44/70 (62%), Gaps = 5/70 (7%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 230
V N+G PV+G GT+ P EV +A K AI+ G+RH+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 231 RAKFEEGKSK 260
R+K +G K
Sbjct: 66 RSKIADGSVK 75
Score = 33.9 bits (74), Expect = 0.48
Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 2/71 (2%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKI 579
G +P+D K + VD TW A+E + G RQ+E +L K
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 580 KPAVLQIEVAP 612
KP Q+E P
Sbjct: 185 KPVCNQVECHP 195
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 87.8 bits (208), Expect = 3e-17
Identities = 38/70 (54%), Positives = 52/70 (74%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLWC HRP+LV A++ SLKNL L+Y+DLYLIH+P +
Sbjct: 45 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 104
Query: 398 FKEGDDLFPK 427
K G+++ PK
Sbjct: 105 VKPGEEVIPK 114
Score = 51.6 bits (118), Expect = 2e-06
Identities = 27/60 (45%), Positives = 39/60 (65%), Gaps = 5/60 (8%)
Frame = +3
Query: 96 VIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEEGKSK 260
V+G GT+ P EV +A K AI+ G+RH+D AH+Y NE++VG A+R+K +G K
Sbjct: 1 VLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVK 58
Score = 33.9 bits (74), Expect = 0.48
Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 2/71 (2%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKI 579
G +P+D K + VD TW A+E + G RQ+E +L K
Sbjct: 108 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 167
Query: 580 KPAVLQIEVAP 612
KP Q+E P
Sbjct: 168 KPVCNQVECHP 178
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 87.8 bits (208), Expect = 3e-17
Identities = 38/70 (54%), Positives = 52/70 (74%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLWC HRP+LV A++ SLKNL L+Y+DLYLIH+P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 398 FKEGDDLFPK 427
K G+++ PK
Sbjct: 122 VKPGEEVIPK 131
Score = 58.8 bits (136), Expect = 1e-08
Identities = 31/70 (44%), Positives = 44/70 (62%), Gaps = 5/70 (7%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 230
V N+G PV+G GT+ P EV +A K AI+ G+RH+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 231 RAKFEEGKSK 260
R+K +G K
Sbjct: 66 RSKIADGSVK 75
Score = 33.9 bits (74), Expect = 0.48
Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 2/71 (2%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKI 579
G +P+D K + VD TW A+E + G RQ+E +L K
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 580 KPAVLQIEVAP 612
KP Q+E P
Sbjct: 185 KPVCNQVECHP 195
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 87.8 bits (208), Expect = 3e-17
Identities = 38/70 (54%), Positives = 52/70 (74%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLWC HRP+LV A++ SLKNL L+Y+DLYLIH+P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 398 FKEGDDLFPK 427
K G+++ PK
Sbjct: 122 VKPGEEVIPK 131
Score = 58.8 bits (136), Expect = 1e-08
Identities = 31/70 (44%), Positives = 44/70 (62%), Gaps = 5/70 (7%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 230
V N+G PV+G GT+ P EV +A K AI+ G+RH+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 231 RAKFEEGKSK 260
R+K +G K
Sbjct: 66 RSKIADGSVK 75
Score = 33.9 bits (74), Expect = 0.48
Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 2/71 (2%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKI 579
G +P+D K + VD TW A+E + G RQ+E +L K
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 580 KPAVLQIEVAP 612
KP Q+E P
Sbjct: 185 KPVCNQVECHP 195
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 87.8 bits (208), Expect = 3e-17
Identities = 38/70 (54%), Positives = 52/70 (74%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLWC HRP+LV A++ SLKNL L+Y+DLYLIH+P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 398 FKEGDDLFPK 427
K G+++ PK
Sbjct: 122 VKPGEEVIPK 131
Score = 58.8 bits (136), Expect = 1e-08
Identities = 31/70 (44%), Positives = 44/70 (62%), Gaps = 5/70 (7%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 230
V N+G PV+G GT+ P EV +A K AI+ G+RH+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 231 RAKFEEGKSK 260
R+K +G K
Sbjct: 66 RSKIADGSVK 75
Score = 33.9 bits (74), Expect = 0.48
Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 2/71 (2%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKI 579
G +P+D K + VD TW A+E + G RQ+E +L K
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 580 KPAVLQIEVAP 612
KP Q+E P
Sbjct: 185 KPVCNQVECHP 195
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 87.8 bits (208), Expect = 3e-17
Identities = 38/70 (54%), Positives = 52/70 (74%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLWC HRP+LV A++ SLKNL L+Y+DLYLIH+P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 398 FKEGDDLFPK 427
K G+++ PK
Sbjct: 122 VKPGEEVIPK 131
Score = 58.8 bits (136), Expect = 1e-08
Identities = 31/70 (44%), Positives = 44/70 (62%), Gaps = 5/70 (7%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 230
V N+G PV+G GT+ P EV +A K AI+ G+RH+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 231 RAKFEEGKSK 260
R+K +G K
Sbjct: 66 RSKIADGSVK 75
Score = 33.9 bits (74), Expect = 0.48
Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 2/71 (2%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKI 579
G +P+D K + VD TW A+E + G RQ+E +L K
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 580 KPAVLQIEVAP 612
KP Q+E P
Sbjct: 185 KPVCNQVECHP 195
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 87.8 bits (208), Expect = 3e-17
Identities = 38/70 (54%), Positives = 52/70 (74%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLWC HRP+LV A++ SLKNL L+Y+DLYLIH+P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 398 FKEGDDLFPK 427
K G+++ PK
Sbjct: 122 VKPGEEVIPK 131
Score = 58.8 bits (136), Expect = 1e-08
Identities = 31/70 (44%), Positives = 44/70 (62%), Gaps = 5/70 (7%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 230
V N+G PV+G GT+ P EV +A K AI+ G+RH+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 231 RAKFEEGKSK 260
R+K +G K
Sbjct: 66 RSKIADGSVK 75
Score = 33.9 bits (74), Expect = 0.48
Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 2/71 (2%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKI 579
G +P+D K + VD TW A+E + G RQ+E +L K
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 580 KPAVLQIEVAP 612
KP Q+E P
Sbjct: 185 KPVCNQVECHP 195
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 87.8 bits (208), Expect = 3e-17
Identities = 38/70 (54%), Positives = 52/70 (74%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLWC HRP+LV A++ SLKNL L+Y+DLYLIH+P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 398 FKEGDDLFPK 427
K G+++ PK
Sbjct: 122 VKPGEEVIPK 131
Score = 58.8 bits (136), Expect = 1e-08
Identities = 31/70 (44%), Positives = 44/70 (62%), Gaps = 5/70 (7%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 230
V N+G PV+G GT+ P EV +A K AI+ G+RH+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 231 RAKFEEGKSK 260
R+K +G K
Sbjct: 66 RSKIADGSVK 75
Score = 33.9 bits (74), Expect = 0.48
Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 2/71 (2%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKI 579
G +P+D K + VD TW A+E + G RQ+E +L K
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 580 KPAVLQIEVAP 612
KP Q+E P
Sbjct: 185 KPVCNQVECHP 195
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 87.8 bits (208), Expect = 3e-17
Identities = 38/70 (54%), Positives = 52/70 (74%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLWC HRP+LV A++ SLKNL L+Y+DLYLIH+P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 398 FKEGDDLFPK 427
K G+++ PK
Sbjct: 122 VKPGEEVIPK 131
Score = 58.8 bits (136), Expect = 1e-08
Identities = 31/70 (44%), Positives = 44/70 (62%), Gaps = 5/70 (7%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 230
V N+G PV+G GT+ P EV +A K AI+ G+RH+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 231 RAKFEEGKSK 260
R+K +G K
Sbjct: 66 RSKIADGSVK 75
Score = 33.9 bits (74), Expect = 0.48
Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 2/71 (2%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKI 579
G +P+D K + VD TW A+E + G RQ+E +L K
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 580 KPAVLQIEVAP 612
KP Q+E P
Sbjct: 185 KPVCNQVECHP 195
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 85.0 bits (201), Expect = 2e-16
Identities = 37/70 (52%), Positives = 51/70 (72%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLWC HRP+L A++ SLKNL L+Y+DLYLIH+P +
Sbjct: 59 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHFPVS 118
Query: 398 FKEGDDLFPK 427
K G+++ PK
Sbjct: 119 VKPGEEVIPK 128
Score = 58.8 bits (136), Expect = 1e-08
Identities = 31/70 (44%), Positives = 44/70 (62%), Gaps = 5/70 (7%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 230
V N+G PV+G GT+ P EV +A K AI+ G+RH+D AH+Y NE++VG A+
Sbjct: 5 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 62
Query: 231 RAKFEEGKSK 260
R+K +G K
Sbjct: 63 RSKIADGSVK 72
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 84.2 bits (199), Expect = 3e-16
Identities = 36/70 (51%), Positives = 51/70 (72%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLWCTF +P +V+ A+++SLK L L+Y+DLYL+H+P A
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMA 121
Query: 398 FKEGDDLFPK 427
K G+ PK
Sbjct: 122 LKPGETPLPK 131
Score = 54.4 bits (125), Expect = 3e-07
Identities = 28/68 (41%), Positives = 42/68 (61%), Gaps = 3/68 (4%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAV---KDAIDIGYRHVDCAHIYLNEKEVGDALRA 236
V N+G PV+G GT+ +AV K AI+ G+RH+D A++Y NE++VG A+R+
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 237 KFEEGKSK 260
K +G K
Sbjct: 68 KIADGSVK 75
Score = 35.9 bits (79), Expect = 0.12
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 2/74 (2%)
Frame = +1
Query: 397 LQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV-- 570
L+ G P+P+D K I VD TW +E + G RQ+E +L
Sbjct: 122 LKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPG 181
Query: 571 AKIKPAVLQIEVAP 612
K KP Q+E P
Sbjct: 182 LKYKPVCNQVECHP 195
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 84.2 bits (199), Expect = 3e-16
Identities = 36/70 (51%), Positives = 51/70 (72%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLWCTF +P +V+ A+++SLK L L+Y+DLYL+H+P A
Sbjct: 47 GLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMA 106
Query: 398 FKEGDDLFPK 427
K G+ PK
Sbjct: 107 LKPGETPLPK 116
Score = 50.0 bits (114), Expect = 7e-06
Identities = 25/59 (42%), Positives = 38/59 (64%), Gaps = 3/59 (5%)
Frame = +3
Query: 93 PVIGLGTWKSKPGEVTQAV---KDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEEGKSK 260
PV+G GT+ +AV K AI+ G+RH+D A++Y NE++VG A+R+K +G K
Sbjct: 2 PVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVK 60
Score = 35.9 bits (79), Expect = 0.12
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 2/74 (2%)
Frame = +1
Query: 397 LQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV-- 570
L+ G P+P+D K I VD TW +E + G RQ+E +L
Sbjct: 107 LKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPG 166
Query: 571 AKIKPAVLQIEVAP 612
K KP Q+E P
Sbjct: 167 LKYKPVCNQVECHP 180
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 84.2 bits (199), Expect = 3e-16
Identities = 36/67 (53%), Positives = 49/67 (73%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 245
V+ + G+ P+IGLGTWKS+PG+V AVK A+ +GYRH+DCA IY NE E+G+AL+
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65
Query: 246 EGKSKER 266
GK+ R
Sbjct: 66 PGKAVPR 72
Score = 82.6 bits (195), Expect = 1e-15
Identities = 34/60 (56%), Positives = 47/60 (78%)
Frame = +2
Query: 248 RKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQAFKEGDDLFPK 427
+ + RE++F+TSKLW T H P+ VE A++ +L +L LEYLDLYL+HWP AF+ GD+ FPK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Score = 54.4 bits (125), Expect = 3e-07
Identities = 27/69 (39%), Positives = 38/69 (55%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEVAKIKP 585
G P P++++ + Y +TW ALEALV KG RQI+ +L VA ++P
Sbjct: 121 GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP 180
Query: 586 AVLQIEVAP 612
AVLQ+E P
Sbjct: 181 AVLQVECHP 189
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 84.2 bits (199), Expect = 3e-16
Identities = 36/70 (51%), Positives = 51/70 (72%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLWCTF +P +V+ A+++SLK L L+Y+DLYL+H+P A
Sbjct: 60 GLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMA 119
Query: 398 FKEGDDLFPK 427
K G+ PK
Sbjct: 120 LKPGETPLPK 129
Score = 54.4 bits (125), Expect = 3e-07
Identities = 28/68 (41%), Positives = 42/68 (61%), Gaps = 3/68 (4%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAV---KDAIDIGYRHVDCAHIYLNEKEVGDALRA 236
V N+G PV+G GT+ +AV K AI+ G+RH+D A++Y NE++VG A+R+
Sbjct: 6 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 65
Query: 237 KFEEGKSK 260
K +G K
Sbjct: 66 KIADGSVK 73
Score = 35.9 bits (79), Expect = 0.12
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 2/74 (2%)
Frame = +1
Query: 397 LQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV-- 570
L+ G P+P+D K I VD TW +E + G RQ+E +L
Sbjct: 120 LKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPG 179
Query: 571 AKIKPAVLQIEVAP 612
K KP Q+E P
Sbjct: 180 LKYKPVCNQVECHP 193
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 84.2 bits (199), Expect = 3e-16
Identities = 36/67 (53%), Positives = 49/67 (73%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 245
V+ + G+ P+IGLGTWKS+PG+V AVK A+ +GYRH+DCA IY NE E+G+AL+
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65
Query: 246 EGKSKER 266
GK+ R
Sbjct: 66 PGKAVPR 72
Score = 82.6 bits (195), Expect = 1e-15
Identities = 34/60 (56%), Positives = 47/60 (78%)
Frame = +2
Query: 248 RKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQAFKEGDDLFPK 427
+ + RE++F+TSKLW T H P+ VE A++ +L +L LEYLDLYL+HWP AF+ GD+ FPK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Score = 54.4 bits (125), Expect = 3e-07
Identities = 27/69 (39%), Positives = 38/69 (55%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEVAKIKP 585
G P P++++ + Y +TW ALEALV KG RQI+ +L VA ++P
Sbjct: 121 GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP 180
Query: 586 AVLQIEVAP 612
AVLQ+E P
Sbjct: 181 AVLQVECHP 189
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 84.2 bits (199), Expect = 3e-16
Identities = 36/67 (53%), Positives = 49/67 (73%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 245
V+ + G+ P+IGLGTWKS+PG+V AVK A+ +GYRH+DCA IY NE E+G+AL+
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65
Query: 246 EGKSKER 266
GK+ R
Sbjct: 66 PGKAVPR 72
Score = 82.6 bits (195), Expect = 1e-15
Identities = 34/60 (56%), Positives = 47/60 (78%)
Frame = +2
Query: 248 RKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQAFKEGDDLFPK 427
+ + RE++F+TSKLW T H P+ VE A++ +L +L LEYLDLYL+HWP AF+ GD+ FPK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Score = 54.4 bits (125), Expect = 3e-07
Identities = 27/69 (39%), Positives = 38/69 (55%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEVAKIKP 585
G P P++++ + Y +TW ALEALV KG RQI+ +L VA ++P
Sbjct: 121 GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP 180
Query: 586 AVLQIEVAP 612
AVLQ+E P
Sbjct: 181 AVLQVECHP 189
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 84.2 bits (199), Expect = 3e-16
Identities = 36/70 (51%), Positives = 51/70 (72%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLWCTF +P +V+ A+++SLK L L+Y+DLYL+H+P A
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMA 121
Query: 398 FKEGDDLFPK 427
K G+ PK
Sbjct: 122 LKPGETPLPK 131
Score = 54.4 bits (125), Expect = 3e-07
Identities = 28/68 (41%), Positives = 42/68 (61%), Gaps = 3/68 (4%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAV---KDAIDIGYRHVDCAHIYLNEKEVGDALRA 236
V N+G PV+G GT+ +AV K AI+ G+RH+D A++Y NE++VG A+R+
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 237 KFEEGKSK 260
K +G K
Sbjct: 68 KIADGSVK 75
Score = 35.9 bits (79), Expect = 0.12
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 2/74 (2%)
Frame = +1
Query: 397 LQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV-- 570
L+ G P+P+D K I VD TW +E + G RQ+E +L
Sbjct: 122 LKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKPG 181
Query: 571 AKIKPAVLQIEVAP 612
K KP Q+E P
Sbjct: 182 LKYKPVCNQVECHP 195
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 84.2 bits (199), Expect = 3e-16
Identities = 36/67 (53%), Positives = 49/67 (73%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 245
V+ + G+ P+IGLGTWKS+PG+V AVK A+ +GYRH+DCA IY NE E+G+AL+
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65
Query: 246 EGKSKER 266
GK+ R
Sbjct: 66 PGKAVPR 72
Score = 82.6 bits (195), Expect = 1e-15
Identities = 34/60 (56%), Positives = 47/60 (78%)
Frame = +2
Query: 248 RKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQAFKEGDDLFPK 427
+ + RE++F+TSKLW T H P+ VE A++ +L +L LEYLDLYL+HWP AF+ GD+ FPK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Score = 54.4 bits (125), Expect = 3e-07
Identities = 27/69 (39%), Positives = 38/69 (55%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEVAKIKP 585
G P P++++ + Y +TW ALEALV KG RQI+ +L VA ++P
Sbjct: 121 GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP 180
Query: 586 AVLQIEVAP 612
AVLQ+E P
Sbjct: 181 AVLQVECHP 189
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 84.2 bits (199), Expect = 3e-16
Identities = 36/67 (53%), Positives = 49/67 (73%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 245
V+ + G+ P+IGLGTWKS+PG+V AVK A+ +GYRH+DCA IY NE E+G+AL+
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65
Query: 246 EGKSKER 266
GK+ R
Sbjct: 66 PGKAVPR 72
Score = 82.6 bits (195), Expect = 1e-15
Identities = 34/60 (56%), Positives = 47/60 (78%)
Frame = +2
Query: 248 RKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQAFKEGDDLFPK 427
+ + RE++F+TSKLW T H P+ VE A++ +L +L LEYLDLYL+HWP AF+ GD+ FPK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Score = 54.4 bits (125), Expect = 3e-07
Identities = 27/69 (39%), Positives = 38/69 (55%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEVAKIKP 585
G P P++++ + Y +TW ALEALV KG RQI+ +L VA ++P
Sbjct: 121 GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP 180
Query: 586 AVLQIEVAP 612
AVLQ+E P
Sbjct: 181 AVLQVECHP 189
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 84.2 bits (199), Expect = 3e-16
Identities = 36/67 (53%), Positives = 49/67 (73%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 245
V+ + G+ P+IGLGTWKS+PG+V AVK A+ +GYRH+DCA IY NE E+G+AL+
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65
Query: 246 EGKSKER 266
GK+ R
Sbjct: 66 PGKAVPR 72
Score = 82.6 bits (195), Expect = 1e-15
Identities = 34/60 (56%), Positives = 47/60 (78%)
Frame = +2
Query: 248 RKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQAFKEGDDLFPK 427
+ + RE++F+TSKLW T H P+ VE A++ +L +L LEYLDLYL+HWP AF+ GD+ FPK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Score = 54.4 bits (125), Expect = 3e-07
Identities = 27/69 (39%), Positives = 38/69 (55%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEVAKIKP 585
G P P++++ + Y +TW ALEALV KG RQI+ +L VA ++P
Sbjct: 121 GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP 180
Query: 586 AVLQIEVAP 612
AVLQ+E P
Sbjct: 181 AVLQVECHP 189
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 84.2 bits (199), Expect = 3e-16
Identities = 36/67 (53%), Positives = 49/67 (73%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 245
V+ + G+ P+IGLGTWKS+PG+V AVK A+ +GYRH+DCA IY NE E+G+AL+
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65
Query: 246 EGKSKER 266
GK+ R
Sbjct: 66 PGKAVPR 72
Score = 82.6 bits (195), Expect = 1e-15
Identities = 34/60 (56%), Positives = 47/60 (78%)
Frame = +2
Query: 248 RKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQAFKEGDDLFPK 427
+ + RE++F+TSKLW T H P+ VE A++ +L +L LEYLDLYL+HWP AF+ GD+ FPK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 84.2 bits (199), Expect = 3e-16
Identities = 36/70 (51%), Positives = 51/70 (72%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLWCTF +P +V+ A+++SLK L L+Y+DLYL+H+P A
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMA 121
Query: 398 FKEGDDLFPK 427
K G+ PK
Sbjct: 122 LKPGETPLPK 131
Score = 54.4 bits (125), Expect = 3e-07
Identities = 28/68 (41%), Positives = 42/68 (61%), Gaps = 3/68 (4%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAV---KDAIDIGYRHVDCAHIYLNEKEVGDALRA 236
V N+G PV+G GT+ +AV K AI+ G+RH+D A++Y NE++VG A+R+
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 237 KFEEGKSK 260
K +G K
Sbjct: 68 KIADGSVK 75
Score = 35.9 bits (79), Expect = 0.12
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 2/74 (2%)
Frame = +1
Query: 397 LQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV-- 570
L+ G P+P+D K I VD TW +E + G RQ+E +L
Sbjct: 122 LKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPG 181
Query: 571 AKIKPAVLQIEVAP 612
K KP Q+E P
Sbjct: 182 LKYKPVCNQVECHP 195
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 84.2 bits (199), Expect = 3e-16
Identities = 36/67 (53%), Positives = 49/67 (73%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 245
V+ + G+ P+IGLGTWKS+PG+V AVK A+ +GYRH+DCA IY NE E+G+AL+
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65
Query: 246 EGKSKER 266
GK+ R
Sbjct: 66 PGKAVPR 72
Score = 82.6 bits (195), Expect = 1e-15
Identities = 34/60 (56%), Positives = 47/60 (78%)
Frame = +2
Query: 248 RKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQAFKEGDDLFPK 427
+ + RE++F+TSKLW T H P+ VE A++ +L +L LEYLDLYL+HWP AF+ GD+ FPK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Score = 54.4 bits (125), Expect = 3e-07
Identities = 27/69 (39%), Positives = 38/69 (55%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEVAKIKP 585
G P P++++ + Y +TW ALEALV KG RQI+ +L VA ++P
Sbjct: 121 GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP 180
Query: 586 AVLQIEVAP 612
AVLQ+E P
Sbjct: 181 AVLQVECHP 189
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 84.2 bits (199), Expect = 3e-16
Identities = 36/67 (53%), Positives = 49/67 (73%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 245
V+ + G+ P+IGLGTWKS+PG+V AVK A+ +GYRH+DCA IY NE E+G+AL+
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65
Query: 246 EGKSKER 266
GK+ R
Sbjct: 66 PGKAVPR 72
Score = 82.6 bits (195), Expect = 1e-15
Identities = 34/60 (56%), Positives = 47/60 (78%)
Frame = +2
Query: 248 RKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQAFKEGDDLFPK 427
+ + RE++F+TSKLW T H P+ VE A++ +L +L LEYLDLYL+HWP AF+ GD+ FPK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Score = 54.4 bits (125), Expect = 3e-07
Identities = 27/69 (39%), Positives = 38/69 (55%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEVAKIKP 585
G P P++++ + Y +TW ALEALV KG RQI+ +L VA ++P
Sbjct: 121 GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP 180
Query: 586 AVLQIEVAP 612
AVLQ+E P
Sbjct: 181 AVLQVECHP 189
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 84.2 bits (199), Expect = 3e-16
Identities = 36/70 (51%), Positives = 51/70 (72%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLWCTF +P +V+ A+++SLK L L+Y+DLYL+H+P A
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMA 121
Query: 398 FKEGDDLFPK 427
K G+ PK
Sbjct: 122 LKPGETPLPK 131
Score = 54.4 bits (125), Expect = 3e-07
Identities = 28/68 (41%), Positives = 42/68 (61%), Gaps = 3/68 (4%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAV---KDAIDIGYRHVDCAHIYLNEKEVGDALRA 236
V N+G PV+G GT+ +AV K AI+ G+RH+D A++Y NE++VG A+R+
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 237 KFEEGKSK 260
K +G K
Sbjct: 68 KIADGSVK 75
Score = 36.3 bits (80), Expect = 0.090
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 2/74 (2%)
Frame = +1
Query: 397 LQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV-- 570
L+ G P+P+D K I VD TW +E + G RQ+E +L
Sbjct: 122 LKPGETPLPKDENGKVIFDTVDLCATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPG 181
Query: 571 AKIKPAVLQIEVAP 612
K KP Q+E P
Sbjct: 182 LKYKPVCNQVECHP 195
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 84.2 bits (199), Expect = 3e-16
Identities = 36/70 (51%), Positives = 51/70 (72%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLWCTF +P +V+ A+++SLK L L+Y+DLYL+H+P A
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMA 121
Query: 398 FKEGDDLFPK 427
K G+ PK
Sbjct: 122 LKPGETPLPK 131
Score = 54.4 bits (125), Expect = 3e-07
Identities = 28/68 (41%), Positives = 42/68 (61%), Gaps = 3/68 (4%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAV---KDAIDIGYRHVDCAHIYLNEKEVGDALRA 236
V N+G PV+G GT+ +AV K AI+ G+RH+D A++Y NE++VG A+R+
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 237 KFEEGKSK 260
K +G K
Sbjct: 68 KIADGSVK 75
Score = 35.9 bits (79), Expect = 0.12
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 2/74 (2%)
Frame = +1
Query: 397 LQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV-- 570
L+ G P+P+D K I VD TW +E + G RQ+E +L
Sbjct: 122 LKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPG 181
Query: 571 AKIKPAVLQIEVAP 612
K KP Q+E P
Sbjct: 182 LKYKPVCNQVECHP 195
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 84.2 bits (199), Expect = 3e-16
Identities = 36/70 (51%), Positives = 51/70 (72%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLWCTF +P +V+ A+++SLK L L+Y+DLYL+H+P A
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMA 121
Query: 398 FKEGDDLFPK 427
K G+ PK
Sbjct: 122 LKPGETPLPK 131
Score = 54.4 bits (125), Expect = 3e-07
Identities = 28/68 (41%), Positives = 42/68 (61%), Gaps = 3/68 (4%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAV---KDAIDIGYRHVDCAHIYLNEKEVGDALRA 236
V N+G PV+G GT+ +AV K AI+ G+RH+D A++Y NE++VG A+R+
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 237 KFEEGKSK 260
K +G K
Sbjct: 68 KIADGSVK 75
Score = 35.9 bits (79), Expect = 0.12
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 2/74 (2%)
Frame = +1
Query: 397 LQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV-- 570
L+ G P+P+D K I VD TW +E + G RQ+E +L
Sbjct: 122 LKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPG 181
Query: 571 AKIKPAVLQIEVAP 612
K KP Q+E P
Sbjct: 182 LKYKPVCNQVECHP 195
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 83.8 bits (198), Expect = 5e-16
Identities = 37/70 (52%), Positives = 51/70 (72%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLW HRP+LV A++ SLKNL L+Y+DLYLIH+P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 398 FKEGDDLFPK 427
K G+++ PK
Sbjct: 122 VKPGEEVIPK 131
Score = 58.8 bits (136), Expect = 1e-08
Identities = 31/70 (44%), Positives = 44/70 (62%), Gaps = 5/70 (7%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 230
V N+G PV+G GT+ P EV +AVK AI+ G+ H+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 231 RAKFEEGKSK 260
R+K +G K
Sbjct: 66 RSKIADGSVK 75
Score = 31.5 bits (68), Expect = 2.5
Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 2/71 (2%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKI 579
G +P+D K + VD TW A+E + G R +E +L K
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184
Query: 580 KPAVLQIEVAP 612
KP Q+E P
Sbjct: 185 KPVCNQVECHP 195
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 83.8 bits (198), Expect = 5e-16
Identities = 37/70 (52%), Positives = 51/70 (72%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLW HRP+LV A++ SLKNL L+Y+DLYLIH+P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 398 FKEGDDLFPK 427
K G+++ PK
Sbjct: 122 VKPGEEVIPK 131
Score = 58.8 bits (136), Expect = 1e-08
Identities = 31/70 (44%), Positives = 44/70 (62%), Gaps = 5/70 (7%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 230
V N+G PV+G GT+ P EV +AVK AI+ G+ H+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 231 RAKFEEGKSK 260
R+K +G K
Sbjct: 66 RSKIADGSVK 75
Score = 29.9 bits (64), Expect = 7.8
Identities = 19/71 (26%), Positives = 28/71 (39%), Gaps = 2/71 (2%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKI 579
G +P+D K + VD TW A+E + G R +E +L K
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKY 184
Query: 580 KPAVLQIEVAP 612
+P Q+E P
Sbjct: 185 EPVCNQVECHP 195
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 83.8 bits (198), Expect = 5e-16
Identities = 37/70 (52%), Positives = 51/70 (72%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLW HRP+LV A++ SLKNL L+Y+DLYLIH+P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 398 FKEGDDLFPK 427
K G+++ PK
Sbjct: 122 VKPGEEVIPK 131
Score = 58.8 bits (136), Expect = 1e-08
Identities = 31/70 (44%), Positives = 44/70 (62%), Gaps = 5/70 (7%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 230
V N+G PV+G GT+ P EV +AVK AI+ G+ H+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 231 RAKFEEGKSK 260
R+K +G K
Sbjct: 66 RSKIADGSVK 75
Score = 31.5 bits (68), Expect = 2.5
Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 2/71 (2%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKI 579
G +P+D K + VD TW A+E + G R +E +L K
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184
Query: 580 KPAVLQIEVAP 612
KP Q+E P
Sbjct: 185 KPVCNQVECHP 195
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 83.8 bits (198), Expect = 5e-16
Identities = 37/70 (52%), Positives = 51/70 (72%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLW HRP+LV A++ SLKNL L+Y+DLYLIH+P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 398 FKEGDDLFPK 427
K G+++ PK
Sbjct: 122 VKPGEEVIPK 131
Score = 58.8 bits (136), Expect = 1e-08
Identities = 31/70 (44%), Positives = 44/70 (62%), Gaps = 5/70 (7%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 230
V N+G PV+G GT+ P EV +AVK AI+ G+ H+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 231 RAKFEEGKSK 260
R+K +G K
Sbjct: 66 RSKIADGSVK 75
Score = 31.5 bits (68), Expect = 2.5
Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 2/71 (2%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKI 579
G +P+D K + VD TW A+E + G R +E +L K
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184
Query: 580 KPAVLQIEVAP 612
KP Q+E P
Sbjct: 185 KPVCNQVECHP 195
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 83.8 bits (198), Expect = 5e-16
Identities = 37/70 (52%), Positives = 51/70 (72%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLW HRP+LV A++ SLKNL L+Y+DLYLIH+P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 398 FKEGDDLFPK 427
K G+++ PK
Sbjct: 122 VKPGEEVIPK 131
Score = 58.8 bits (136), Expect = 1e-08
Identities = 31/70 (44%), Positives = 44/70 (62%), Gaps = 5/70 (7%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 230
V N+G PV+G GT+ P EV +AVK AI+ G+ H+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 231 RAKFEEGKSK 260
R+K +G K
Sbjct: 66 RSKIADGSVK 75
Score = 31.5 bits (68), Expect = 2.5
Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 2/71 (2%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKI 579
G +P+D K + VD TW A+E + G R +E +L K
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184
Query: 580 KPAVLQIEVAP 612
KP Q+E P
Sbjct: 185 KPVCNQVECHP 195
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 83.8 bits (198), Expect = 5e-16
Identities = 37/70 (52%), Positives = 51/70 (72%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLW HRP+LV A++ SLKNL L+Y+DLYLIH+P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 398 FKEGDDLFPK 427
K G+++ PK
Sbjct: 122 VKPGEEVIPK 131
Score = 58.8 bits (136), Expect = 1e-08
Identities = 31/70 (44%), Positives = 44/70 (62%), Gaps = 5/70 (7%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 230
V N+G PV+G GT+ P EV +AVK AI+ G+ H+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 231 RAKFEEGKSK 260
R+K +G K
Sbjct: 66 RSKIADGSVK 75
Score = 31.5 bits (68), Expect = 2.5
Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 2/71 (2%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKI 579
G +P+D K + VD TW A+E + G R +E +L K
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184
Query: 580 KPAVLQIEVAP 612
KP Q+E P
Sbjct: 185 KPVCNQVECHP 195
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 83.8 bits (198), Expect = 5e-16
Identities = 37/70 (52%), Positives = 51/70 (72%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLW HRP+LV A++ SLKNL L+Y+DLYLIH+P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 398 FKEGDDLFPK 427
K G+++ PK
Sbjct: 122 VKPGEEVIPK 131
Score = 58.8 bits (136), Expect = 1e-08
Identities = 31/70 (44%), Positives = 44/70 (62%), Gaps = 5/70 (7%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 230
V N+G PV+G GT+ P EV +AVK AI+ G+ H+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 231 RAKFEEGKSK 260
R+K +G K
Sbjct: 66 RSKIADGSVK 75
Score = 31.5 bits (68), Expect = 2.5
Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 2/71 (2%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKI 579
G +P+D K + VD TW A+E + G R +E +L K
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184
Query: 580 KPAVLQIEVAP 612
KP Q+E P
Sbjct: 185 KPVCNQVECHP 195
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 83.8 bits (198), Expect = 5e-16
Identities = 37/70 (52%), Positives = 51/70 (72%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLW HRP+LV A++ SLKNL L+Y+DLYLIH+P +
Sbjct: 75 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 134
Query: 398 FKEGDDLFPK 427
K G+++ PK
Sbjct: 135 VKPGEEVIPK 144
Score = 58.8 bits (136), Expect = 1e-08
Identities = 31/70 (44%), Positives = 44/70 (62%), Gaps = 5/70 (7%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 230
V N+G PV+G GT+ P EV +AVK AI+ G+ H+D AH+Y NE++VG A+
Sbjct: 21 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 78
Query: 231 RAKFEEGKSK 260
R+K +G K
Sbjct: 79 RSKIADGSVK 88
Score = 31.5 bits (68), Expect = 2.5
Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 2/71 (2%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKI 579
G +P+D K + VD TW A+E + G R +E +L K
Sbjct: 138 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 197
Query: 580 KPAVLQIEVAP 612
KP Q+E P
Sbjct: 198 KPVCNQVECHP 208
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 83.8 bits (198), Expect = 5e-16
Identities = 37/70 (52%), Positives = 51/70 (72%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLW HRP+LV A++ SLKNL L+Y+DLYLIH+P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 398 FKEGDDLFPK 427
K G+++ PK
Sbjct: 122 VKPGEEVIPK 131
Score = 58.8 bits (136), Expect = 1e-08
Identities = 31/70 (44%), Positives = 44/70 (62%), Gaps = 5/70 (7%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 230
V N+G PV+G GT+ P EV +AVK AI+ G+ H+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 231 RAKFEEGKSK 260
R+K +G K
Sbjct: 66 RSKIADGSVK 75
Score = 31.5 bits (68), Expect = 2.5
Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 2/71 (2%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKI 579
G +P+D K + VD TW A+E + G R +E +L K
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184
Query: 580 KPAVLQIEVAP 612
KP Q+E P
Sbjct: 185 KPVCNQVECHP 195
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 83.8 bits (198), Expect = 5e-16
Identities = 37/70 (52%), Positives = 51/70 (72%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLW HRP+LV A++ SLKNL L+Y+DLYLIH+P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 398 FKEGDDLFPK 427
K G+++ PK
Sbjct: 122 VKPGEEVIPK 131
Score = 58.8 bits (136), Expect = 1e-08
Identities = 31/70 (44%), Positives = 44/70 (62%), Gaps = 5/70 (7%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 230
V N+G PV+G GT+ P EV +AVK AI+ G+ H+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 231 RAKFEEGKSK 260
R+K +G K
Sbjct: 66 RSKIADGSVK 75
Score = 31.5 bits (68), Expect = 2.5
Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 2/71 (2%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKI 579
G +P+D K + VD TW A+E + G R +E +L K
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184
Query: 580 KPAVLQIEVAP 612
KP Q+E P
Sbjct: 185 KPVCNQVECHP 195
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 83.8 bits (198), Expect = 5e-16
Identities = 37/70 (52%), Positives = 51/70 (72%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLW HRP+LV A++ SLKNL L+Y+DLYLIH+P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 398 FKEGDDLFPK 427
K G+++ PK
Sbjct: 122 VKPGEEVIPK 131
Score = 58.8 bits (136), Expect = 1e-08
Identities = 31/70 (44%), Positives = 44/70 (62%), Gaps = 5/70 (7%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 230
V N+G PV+G GT+ P EV +AVK AI+ G+ H+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 231 RAKFEEGKSK 260
R+K +G K
Sbjct: 66 RSKIADGSVK 75
Score = 31.5 bits (68), Expect = 2.5
Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 2/71 (2%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKI 579
G +P+D K + VD TW A+E + G R +E +L K
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184
Query: 580 KPAVLQIEVAP 612
KP Q+E P
Sbjct: 185 KPVCNQVECHP 195
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 83.0 bits (196), Expect = 8e-16
Identities = 37/70 (52%), Positives = 50/70 (71%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLW HRP+LV A++ SLKNL L+Y DLYLIH+P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLIHFPVS 121
Query: 398 FKEGDDLFPK 427
K G+++ PK
Sbjct: 122 VKPGEEVIPK 131
Score = 60.5 bits (140), Expect = 5e-09
Identities = 32/70 (45%), Positives = 44/70 (62%), Gaps = 5/70 (7%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 230
V N+G PV+G GT+ P EV +AVK AI+ GY H+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGYHHIDSAHVYNNEEQVGLAI 65
Query: 231 RAKFEEGKSK 260
R+K +G K
Sbjct: 66 RSKIADGSVK 75
Score = 29.9 bits (64), Expect = 7.8
Identities = 19/71 (26%), Positives = 28/71 (39%), Gaps = 2/71 (2%)
Frame = +1
Query: 406 GRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKI 579
G +P+D K + VD TW A+E + G R +E +L K
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKY 184
Query: 580 KPAVLQIEVAP 612
+P Q+E P
Sbjct: 185 EPVCNQVECHP 195
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 83.0 bits (196), Expect = 8e-16
Identities = 37/69 (53%), Positives = 49/69 (71%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLW TFHRP+LV A++ SLK L+Y+DLYLIH P +
Sbjct: 64 GLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 123
Query: 398 FKEGDDLFP 424
K G++L P
Sbjct: 124 LKPGEELSP 132
Score = 57.2 bits (132), Expect = 4e-08
Identities = 32/71 (45%), Positives = 45/71 (63%), Gaps = 6/71 (8%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTW------KSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDA 227
V N+G PV+G GT+ +SK EVT K AI+ G+RH+D AH+Y NE++VG A
Sbjct: 10 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLA 66
Query: 228 LRAKFEEGKSK 260
+R+K +G K
Sbjct: 67 IRSKIADGSVK 77
Score = 32.7 bits (71), Expect = 1.1
Identities = 23/74 (31%), Positives = 29/74 (39%), Gaps = 2/74 (2%)
Frame = +1
Query: 397 LQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV-- 570
L+ G P D K I VD TW A+E + G RQ+E +L
Sbjct: 124 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 183
Query: 571 AKIKPAVLQIEVAP 612
K KP Q+E P
Sbjct: 184 LKYKPVCNQVECHP 197
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 83.0 bits (196), Expect = 8e-16
Identities = 37/69 (53%), Positives = 49/69 (71%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLW TFHRP+LV A++ SLK L+Y+DLYLIH P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 121
Query: 398 FKEGDDLFP 424
K G++L P
Sbjct: 122 LKPGEELSP 130
Score = 57.2 bits (132), Expect = 4e-08
Identities = 32/71 (45%), Positives = 45/71 (63%), Gaps = 6/71 (8%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTW------KSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDA 227
V N+G PV+G GT+ +SK EVT K AI+ G+RH+D AH+Y NE++VG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 228 LRAKFEEGKSK 260
+R+K +G K
Sbjct: 65 IRSKIADGSVK 75
Score = 32.7 bits (71), Expect = 1.1
Identities = 23/74 (31%), Positives = 29/74 (39%), Gaps = 2/74 (2%)
Frame = +1
Query: 397 LQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV-- 570
L+ G P D K I VD TW A+E + G RQ+E +L
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 571 AKIKPAVLQIEVAP 612
K KP Q+E P
Sbjct: 182 LKYKPVCNQVECHP 195
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 83.0 bits (196), Expect = 8e-16
Identities = 37/69 (53%), Positives = 49/69 (71%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLW TFHRP+LV A++ SLK L+Y+DLYLIH P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 121
Query: 398 FKEGDDLFP 424
K G++L P
Sbjct: 122 LKPGEELSP 130
Score = 57.2 bits (132), Expect = 4e-08
Identities = 32/71 (45%), Positives = 45/71 (63%), Gaps = 6/71 (8%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTW------KSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDA 227
V N+G PV+G GT+ +SK EVT K AI+ G+RH+D AH+Y NE++VG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 228 LRAKFEEGKSK 260
+R+K +G K
Sbjct: 65 IRSKIADGSVK 75
Score = 32.7 bits (71), Expect = 1.1
Identities = 23/74 (31%), Positives = 29/74 (39%), Gaps = 2/74 (2%)
Frame = +1
Query: 397 LQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV-- 570
L+ G P D K I VD TW A+E + G RQ+E +L
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 571 AKIKPAVLQIEVAP 612
K KP Q+E P
Sbjct: 182 LKYKPVCNQVECHP 195
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 83.0 bits (196), Expect = 8e-16
Identities = 37/69 (53%), Positives = 49/69 (71%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLW TFHRP+LV A++ SLK L+Y+DLYLIH P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 121
Query: 398 FKEGDDLFP 424
K G++L P
Sbjct: 122 LKPGEELSP 130
Score = 57.2 bits (132), Expect = 4e-08
Identities = 32/71 (45%), Positives = 45/71 (63%), Gaps = 6/71 (8%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTW------KSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDA 227
V N+G PV+G GT+ +SK EVT K AI+ G+RH+D AH+Y NE++VG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 228 LRAKFEEGKSK 260
+R+K +G K
Sbjct: 65 IRSKIADGSVK 75
Score = 32.7 bits (71), Expect = 1.1
Identities = 23/74 (31%), Positives = 29/74 (39%), Gaps = 2/74 (2%)
Frame = +1
Query: 397 LQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV-- 570
L+ G P D K I VD TW A+E + G RQ+E +L
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 571 AKIKPAVLQIEVAP 612
K KP Q+E P
Sbjct: 182 LKYKPVCNQVECHP 195
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 83.0 bits (196), Expect = 8e-16
Identities = 37/69 (53%), Positives = 49/69 (71%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLW TFHRP+LV A++ SLK L+Y+DLYLIH P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 121
Query: 398 FKEGDDLFP 424
K G++L P
Sbjct: 122 LKPGEELSP 130
Score = 57.2 bits (132), Expect = 4e-08
Identities = 32/71 (45%), Positives = 45/71 (63%), Gaps = 6/71 (8%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTW------KSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDA 227
V N+G PV+G GT+ +SK EVT K AI+ G+RH+D AH+Y NE++VG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 228 LRAKFEEGKSK 260
+R+K +G K
Sbjct: 65 IRSKIADGSVK 75
Score = 32.7 bits (71), Expect = 1.1
Identities = 23/74 (31%), Positives = 29/74 (39%), Gaps = 2/74 (2%)
Frame = +1
Query: 397 LQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV-- 570
L+ G P D K I VD TW A+E + G RQ+E +L
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 571 AKIKPAVLQIEVAP 612
K KP Q+E P
Sbjct: 182 LKYKPVCNQVECHP 195
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 83.0 bits (196), Expect = 8e-16
Identities = 37/69 (53%), Positives = 49/69 (71%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLW TFHRP+LV A++ SLK L+Y+DLYLIH P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 121
Query: 398 FKEGDDLFP 424
K G++L P
Sbjct: 122 LKPGEELSP 130
Score = 57.2 bits (132), Expect = 4e-08
Identities = 32/71 (45%), Positives = 45/71 (63%), Gaps = 6/71 (8%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTW------KSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDA 227
V N+G PV+G GT+ +SK EVT K AI+ G+RH+D AH+Y NE++VG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 228 LRAKFEEGKSK 260
+R+K +G K
Sbjct: 65 IRSKIADGSVK 75
Score = 32.7 bits (71), Expect = 1.1
Identities = 23/74 (31%), Positives = 29/74 (39%), Gaps = 2/74 (2%)
Frame = +1
Query: 397 LQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV-- 570
L+ G P D K I VD TW A+E + G RQ+E +L
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 571 AKIKPAVLQIEVAP 612
K KP Q+E P
Sbjct: 182 LKYKPVCNQVECHP 195
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 83.0 bits (196), Expect = 8e-16
Identities = 37/69 (53%), Positives = 49/69 (71%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLW TFHRP+LV A++ SLK L+Y+DLYLIH P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 121
Query: 398 FKEGDDLFP 424
K G++L P
Sbjct: 122 LKPGEELSP 130
Score = 57.2 bits (132), Expect = 4e-08
Identities = 32/71 (45%), Positives = 45/71 (63%), Gaps = 6/71 (8%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTW------KSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDA 227
V N+G PV+G GT+ +SK EVT K AI+ G+RH+D AH+Y NE++VG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 228 LRAKFEEGKSK 260
+R+K +G K
Sbjct: 65 IRSKIADGSVK 75
Score = 32.7 bits (71), Expect = 1.1
Identities = 23/74 (31%), Positives = 29/74 (39%), Gaps = 2/74 (2%)
Frame = +1
Query: 397 LQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV-- 570
L+ G P D K I VD TW A+E + G RQ+E +L
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 571 AKIKPAVLQIEVAP 612
K KP Q+E P
Sbjct: 182 LKYKPVCNQVECHP 195
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 81.4 bits (192), Expect = 2e-15
Identities = 36/69 (52%), Positives = 49/69 (71%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ ++REDIF TSKLW TFHRP+LV A++ SLK L+Y+DLYLIH P +
Sbjct: 62 GLAIRSKIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 121
Query: 398 FKEGDDLFP 424
K G++L P
Sbjct: 122 LKPGEELSP 130
Score = 56.4 bits (130), Expect = 8e-08
Identities = 34/73 (46%), Positives = 47/73 (64%), Gaps = 6/73 (8%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTW------KSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDA 227
V N+G PV+G GT+ +SK EVT K AI+ G+RH+D AH+Y NE++VG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 228 LRAKFEEGKSKER 266
+R+K +G S ER
Sbjct: 65 IRSKIADG-SVER 76
Score = 31.9 bits (69), Expect = 1.9
Identities = 23/74 (31%), Positives = 29/74 (39%), Gaps = 2/74 (2%)
Frame = +1
Query: 397 LQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV-- 570
L+ G P D K I VD TW A+E + G RQ+E +L
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPG 181
Query: 571 AKIKPAVLQIEVAP 612
K KP Q+E P
Sbjct: 182 LKYKPVCNQVECHP 195
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 81.0 bits (191), Expect = 3e-15
Identities = 36/69 (52%), Positives = 48/69 (69%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLWC HRP+LV A++ SLK L+Y+DLYLIH P +
Sbjct: 62 GLAVRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHSPMS 121
Query: 398 FKEGDDLFP 424
K G++L P
Sbjct: 122 LKPGEELSP 130
Score = 58.4 bits (135), Expect = 2e-08
Identities = 31/70 (44%), Positives = 44/70 (62%), Gaps = 5/70 (7%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 230
V N+G PV+G GT+ P EV +A K AI+ G+RH+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAV 65
Query: 231 RAKFEEGKSK 260
R+K +G K
Sbjct: 66 RSKIADGSVK 75
Score = 32.7 bits (71), Expect = 1.1
Identities = 23/74 (31%), Positives = 29/74 (39%), Gaps = 2/74 (2%)
Frame = +1
Query: 397 LQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV-- 570
L+ G P D K I VD TW A+E + G RQ+E +L
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 571 AKIKPAVLQIEVAP 612
K KP Q+E P
Sbjct: 182 LKYKPVCNQVECHP 195
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 81.0 bits (191), Expect = 3e-15
Identities = 32/53 (60%), Positives = 42/53 (79%)
Frame = +3
Query: 93 PVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEEG 251
P +GL +WK+ PG+VT+AVK+AID GYRH DCA+ Y NE+EVG +R K +EG
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEG 57
Score = 77.8 bits (183), Expect = 3e-14
Identities = 33/62 (53%), Positives = 42/62 (67%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + ++ ++RED+FI +KLWCT H+ LVE A + SLK L L YLDLYLIHWP
Sbjct: 47 GAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
Query: 398 FK 403
FK
Sbjct: 107 FK 108
Score = 38.7 bits (86), Expect = 0.017
Identities = 24/67 (35%), Positives = 32/67 (47%), Gaps = 2/67 (2%)
Frame = +1
Query: 418 VPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKIKPAV 591
+P D + IPS D++DTW A+E LV G Q+ER+L + KP
Sbjct: 133 LPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLT 192
Query: 592 LQIEVAP 612
QIE P
Sbjct: 193 NQIECHP 199
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 81.0 bits (191), Expect = 3e-15
Identities = 32/53 (60%), Positives = 42/53 (79%)
Frame = +3
Query: 93 PVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEEG 251
P +GL +WK+ PG+VT+AVK+AID GYRH DCA+ Y NE+EVG +R K +EG
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEG 57
Score = 77.8 bits (183), Expect = 3e-14
Identities = 33/62 (53%), Positives = 42/62 (67%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + ++ ++RED+FI +KLWCT H+ LVE A + SLK L L YLDLYLIHWP
Sbjct: 47 GAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
Query: 398 FK 403
FK
Sbjct: 107 FK 108
Score = 38.7 bits (86), Expect = 0.017
Identities = 24/67 (35%), Positives = 32/67 (47%), Gaps = 2/67 (2%)
Frame = +1
Query: 418 VPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKIKPAV 591
+P D + IPS D++DTW A+E LV G Q+ER+L + KP
Sbjct: 133 LPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLT 192
Query: 592 LQIEVAP 612
QIE P
Sbjct: 193 NQIECHP 199
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 81.0 bits (191), Expect = 3e-15
Identities = 32/53 (60%), Positives = 42/53 (79%)
Frame = +3
Query: 93 PVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEEG 251
P +GL +WK+ PG+VT+AVK+AID GYRH DCA+ Y NE+EVG +R K +EG
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEG 57
Score = 77.8 bits (183), Expect = 3e-14
Identities = 33/62 (53%), Positives = 42/62 (67%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + ++ ++RED+FI +KLWCT H+ LVE A + SLK L L YLDLYLIHWP
Sbjct: 47 GAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
Query: 398 FK 403
FK
Sbjct: 107 FK 108
Score = 38.7 bits (86), Expect = 0.017
Identities = 24/67 (35%), Positives = 32/67 (47%), Gaps = 2/67 (2%)
Frame = +1
Query: 418 VPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKIKPAV 591
+P D + IPS D++DTW A+E LV G Q+ER+L + KP
Sbjct: 133 LPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLT 192
Query: 592 LQIEVAP 612
QIE P
Sbjct: 193 NQIECHP 199
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 81.0 bits (191), Expect = 3e-15
Identities = 32/53 (60%), Positives = 42/53 (79%)
Frame = +3
Query: 93 PVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEEG 251
P +GL +WK+ PG+VT+AVK+AID GYRH DCA+ Y NE+EVG +R K +EG
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEG 57
Score = 77.8 bits (183), Expect = 3e-14
Identities = 33/62 (53%), Positives = 42/62 (67%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + ++ ++RED+FI +KLWCT H+ LVE A + SLK L L YLDLYLIHWP
Sbjct: 47 GAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
Query: 398 FK 403
FK
Sbjct: 107 FK 108
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 81.0 bits (191), Expect = 3e-15
Identities = 32/53 (60%), Positives = 42/53 (79%)
Frame = +3
Query: 93 PVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEEG 251
P +GL +WK+ PG+VT+AVK+AID GYRH DCA+ Y NE+EVG +R K +EG
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEG 57
Score = 77.8 bits (183), Expect = 3e-14
Identities = 33/62 (53%), Positives = 42/62 (67%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + ++ ++RED+FI +KLWCT H+ LVE A + SLK L L YLDLYLIHWP
Sbjct: 47 GAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
Query: 398 FK 403
FK
Sbjct: 107 FK 108
Score = 35.1 bits (77), Expect = 0.21
Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
Frame = +1
Query: 418 VPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKIKPAV 591
+P D + IPS D++DTW A+E LV G Q+ER+L + KP
Sbjct: 133 LPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLT 192
Query: 592 LQI 600
QI
Sbjct: 193 NQI 195
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 81.0 bits (191), Expect = 3e-15
Identities = 32/53 (60%), Positives = 42/53 (79%)
Frame = +3
Query: 93 PVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEEG 251
P +GL +WK+ PG+VT+AVK+AID GYRH DCA+ Y NE+EVG +R K +EG
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEG 57
Score = 77.8 bits (183), Expect = 3e-14
Identities = 33/62 (53%), Positives = 42/62 (67%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + ++ ++RED+FI +KLWCT H+ LVE A + SLK L L YLDLYLIHWP
Sbjct: 47 GAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
Query: 398 FK 403
FK
Sbjct: 107 FK 108
Score = 35.1 bits (77), Expect = 0.21
Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
Frame = +1
Query: 418 VPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV--AKIKPAV 591
+P D + IPS D++DTW A+E LV G Q+ER+L + KP
Sbjct: 133 LPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLT 192
Query: 592 LQI 600
QI
Sbjct: 193 NQI 195
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 80.6 bits (190), Expect = 4e-15
Identities = 36/69 (52%), Positives = 48/69 (69%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ + REDIF TSKLW TFHRP+LV A++ SLK L+Y+DLYLIH P +
Sbjct: 62 GLAIRSKIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 121
Query: 398 FKEGDDLFP 424
K G++L P
Sbjct: 122 LKPGEELSP 130
Score = 56.0 bits (129), Expect = 1e-07
Identities = 31/68 (45%), Positives = 44/68 (64%), Gaps = 6/68 (8%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTW------KSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDA 227
V N+G PV+G GT+ +SK EVT K AI+ G+RH+D AH+Y NE++VG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 228 LRAKFEEG 251
+R+K +G
Sbjct: 65 IRSKIADG 72
Score = 31.9 bits (69), Expect = 1.9
Identities = 23/74 (31%), Positives = 29/74 (39%), Gaps = 2/74 (2%)
Frame = +1
Query: 397 LQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV-- 570
L+ G P D K I VD TW A+E + G RQ+E +L
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPG 181
Query: 571 AKIKPAVLQIEVAP 612
K KP Q+E P
Sbjct: 182 LKYKPVCNQVECHP 195
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 79.8 bits (188), Expect = 7e-15
Identities = 36/69 (52%), Positives = 48/69 (69%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + S++ +KREDIF TSKLW T HRP+LV A++ SLK L+Y+DLYLIH P +
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 121
Query: 398 FKEGDDLFP 424
K G++L P
Sbjct: 122 LKPGEELSP 130
Score = 56.0 bits (129), Expect = 1e-07
Identities = 28/68 (41%), Positives = 43/68 (63%), Gaps = 3/68 (4%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKPGEVTQAV---KDAIDIGYRHVDCAHIYLNEKEVGDALRA 236
V N+G PV+G GT+ ++A+ K AI+ G+RH+D AH+Y NE++VG A+R+
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVSKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 237 KFEEGKSK 260
K +G K
Sbjct: 68 KIADGSVK 75
Score = 32.7 bits (71), Expect = 1.1
Identities = 23/74 (31%), Positives = 29/74 (39%), Gaps = 2/74 (2%)
Frame = +1
Query: 397 LQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DSPTSTGRQIERVLEV-- 570
L+ G P D K I VD TW A+E + G RQ+E +L
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 571 AKIKPAVLQIEVAP 612
K KP Q+E P
Sbjct: 182 LKYKPVCNQVECHP 195
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 72.1 bits (169), Expect = 1e-12
Identities = 29/70 (41%), Positives = 47/70 (67%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + ++ K++REDIF KLW T H P++V ++ +L+ L L+Y+DLY+I P A
Sbjct: 65 GEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMA 124
Query: 398 FKEGDDLFPK 427
FK GD+++P+
Sbjct: 125 FKPGDEIYPR 134
Score = 69.7 bits (163), Expect = 8e-12
Identities = 37/72 (51%), Positives = 48/72 (66%), Gaps = 4/72 (5%)
Frame = +3
Query: 51 AAPVPVIFNNGRTCPVIGLGTW---KSKP-GEVTQAVKDAIDIGYRHVDCAHIYLNEKEV 218
AA + ++G + P+IGLGT+ KS P G +VK AID GYRH+D A+IY NE EV
Sbjct: 5 AASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEV 64
Query: 219 GDALRAKFEEGK 254
G+A+R K EGK
Sbjct: 65 GEAIREKIAEGK 76
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 72.1 bits (169), Expect = 1e-12
Identities = 29/70 (41%), Positives = 47/70 (67%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + ++ K++REDIF KLW T H P++V ++ +L+ L L+Y+DLY+I P A
Sbjct: 65 GEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMA 124
Query: 398 FKEGDDLFPK 427
FK GD+++P+
Sbjct: 125 FKPGDEIYPR 134
Score = 69.7 bits (163), Expect = 8e-12
Identities = 37/72 (51%), Positives = 48/72 (66%), Gaps = 4/72 (5%)
Frame = +3
Query: 51 AAPVPVIFNNGRTCPVIGLGTW---KSKP-GEVTQAVKDAIDIGYRHVDCAHIYLNEKEV 218
AA + ++G + P+IGLGT+ KS P G +VK AID GYRH+D A+IY NE EV
Sbjct: 5 AASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEV 64
Query: 219 GDALRAKFEEGK 254
G+A+R K EGK
Sbjct: 65 GEAIREKIAEGK 76
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 72.1 bits (169), Expect = 1e-12
Identities = 29/70 (41%), Positives = 47/70 (67%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + ++ K++REDIF KLW T H P++V ++ +L+ L L+Y+DLY+I P A
Sbjct: 65 GEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMA 124
Query: 398 FKEGDDLFPK 427
FK GD+++P+
Sbjct: 125 FKPGDEIYPR 134
Score = 69.7 bits (163), Expect = 8e-12
Identities = 37/72 (51%), Positives = 48/72 (66%), Gaps = 4/72 (5%)
Frame = +3
Query: 51 AAPVPVIFNNGRTCPVIGLGTW---KSKP-GEVTQAVKDAIDIGYRHVDCAHIYLNEKEV 218
AA + ++G + P+IGLGT+ KS P G +VK AID GYRH+D A+IY NE EV
Sbjct: 5 AASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEV 64
Query: 219 GDALRAKFEEGK 254
G+A+R K EGK
Sbjct: 65 GEAIREKIAEGK 76
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 72.1 bits (169), Expect = 1e-12
Identities = 29/70 (41%), Positives = 47/70 (67%)
Frame = +2
Query: 218 GGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQA 397
G + ++ K++REDIF KLW T H P++V ++ +L+ L L+Y+DLY+I P A
Sbjct: 65 GEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMA 124
Query: 398 FKEGDDLFPK 427
FK GD+++P+
Sbjct: 125 FKPGDEIYPR 134
Score = 69.7 bits (163), Expect = 8e-12
Identities = 37/72 (51%), Positives = 48/72 (66%), Gaps = 4/72 (5%)
Frame = +3
Query: 51 AAPVPVIFNNGRTCPVIGLGTW---KSKP-GEVTQAVKDAIDIGYRHVDCAHIYLNEKEV 218
AA + ++G + P+IGLGT+ KS P G +VK AID GYRH+D A+IY NE EV
Sbjct: 5 AASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEV 64
Query: 219 GDALRAKFEEGK 254
G+A+R K EGK
Sbjct: 65 GEAIREKIAEGK 76
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 69.7 bits (163), Expect = 8e-12
Identities = 32/72 (44%), Positives = 47/72 (65%)
Frame = +2
Query: 194 HLPQ*EGGGGRLESQV*RRKIKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDL 373
HL + EG G + ++ +KR+DIF T+K+W TF RP+LV+ ++ SLK L L Y+DL
Sbjct: 56 HLNE-EGIGQAIRKKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDL 114
Query: 374 YLIHWPQAFKEG 409
YL H+P + G
Sbjct: 115 YLFHFPVPLQPG 126
Score = 60.5 bits (140), Expect = 5e-09
Identities = 28/70 (40%), Positives = 44/70 (62%), Gaps = 3/70 (4%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWKSKP---GEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRA 236
V N+G+ P++G GT ++ V +AV+ AID+GYRH+D A+ +LNE+ +G A+R
Sbjct: 9 VKLNDGKFMPILGFGTSVARKVAMSNVEEAVQVAIDVGYRHIDSAYTHLNEEGIGQAIRK 68
Query: 237 KFEEGKSKER 266
K G K +
Sbjct: 69 KIANGTVKRK 78
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 69.3 bits (162), Expect = 1e-11
Identities = 32/59 (54%), Positives = 43/59 (72%), Gaps = 1/59 (1%)
Frame = +2
Query: 254 IKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQAFKE-GDDLFPK 427
+KRE+IF T KLW TF R +LV A++ SLK LG +Y+DL++IH P A K+ G +L PK
Sbjct: 77 VKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQPGKELLPK 135
Score = 59.3 bits (137), Expect = 1e-08
Identities = 28/68 (41%), Positives = 42/68 (61%), Gaps = 3/68 (4%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWK---SKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRA 236
V N+G PV+G GT+ + + +A K AID+G+RH+D A++Y NE+EVG A+
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWE 70
Query: 237 KFEEGKSK 260
K +G K
Sbjct: 71 KIADGTVK 78
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 69.3 bits (162), Expect = 1e-11
Identities = 32/59 (54%), Positives = 43/59 (72%), Gaps = 1/59 (1%)
Frame = +2
Query: 254 IKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQAFKE-GDDLFPK 427
+KRE+IF T KLW TF R +LV A++ SLK LG +Y+DL++IH P A K+ G +L PK
Sbjct: 77 VKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQPGKELLPK 135
Score = 59.3 bits (137), Expect = 1e-08
Identities = 28/68 (41%), Positives = 42/68 (61%), Gaps = 3/68 (4%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWK---SKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRA 236
V N+G PV+G GT+ + + +A K AID+G+RH+D A++Y NE+EVG A+
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWE 70
Query: 237 KFEEGKSK 260
K +G K
Sbjct: 71 KIADGTVK 78
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 63.7 bits (148), Expect = 5e-10
Identities = 28/50 (56%), Positives = 37/50 (74%)
Frame = +2
Query: 254 IKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQAFK 403
+KRE+IF T KLW TF R +LV A++ SLK LG +Y+DL++IH P A K
Sbjct: 77 VKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMK 126
Score = 59.3 bits (137), Expect = 1e-08
Identities = 28/68 (41%), Positives = 42/68 (61%), Gaps = 3/68 (4%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWK---SKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRA 236
V N+G PV+G GT+ + + +A K AID+G+RH+D A++Y NE+EVG A+
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWE 70
Query: 237 KFEEGKSK 260
K +G K
Sbjct: 71 KIADGTVK 78
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 63.7 bits (148), Expect = 5e-10
Identities = 28/50 (56%), Positives = 37/50 (74%)
Frame = +2
Query: 254 IKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQAFK 403
+KRE+IF T KLW TF R +LV A++ SLK LG +Y+DL++IH P A K
Sbjct: 77 VKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMK 126
Score = 59.3 bits (137), Expect = 1e-08
Identities = 28/68 (41%), Positives = 42/68 (61%), Gaps = 3/68 (4%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWK---SKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRA 236
V N+G PV+G GT+ + + +A K AID+G+RH+D A++Y NE+EVG A+
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWE 70
Query: 237 KFEEGKSK 260
K +G K
Sbjct: 71 KIADGTVK 78
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 63.7 bits (148), Expect = 5e-10
Identities = 28/50 (56%), Positives = 37/50 (74%)
Frame = +2
Query: 254 IKREDIFITSKLWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQAFK 403
+KRE+IF T KLW TF R +LV A++ SLK LG +Y+DL++IH P A K
Sbjct: 77 VKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMK 126
Score = 59.3 bits (137), Expect = 1e-08
Identities = 28/68 (41%), Positives = 42/68 (61%), Gaps = 3/68 (4%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWK---SKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRA 236
V N+G PV+G GT+ + + +A K AID+G+RH+D A++Y NE+EVG A+
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWE 70
Query: 237 KFEEGKSK 260
K +G K
Sbjct: 71 KIADGTVK 78
>AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto
reductase protein.
Length = 45
Score = 49.6 bits (113), Expect = 9e-06
Identities = 20/41 (48%), Positives = 28/41 (68%)
Frame = +2
Query: 287 LWCTFHRPDLVEEAIKTSLKNLGLEYLDLYLIHWPQAFKEG 409
+W TF RP+LV+ ++ SLK L L Y+DLYL H+P + G
Sbjct: 1 VWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPLQPG 41
>AK027341-1|BAB55047.1| 314|Homo sapiens protein ( Homo sapiens
cDNA FLJ14435 fis, clone HEMBA1007085. ).
Length = 314
Score = 33.1 bits (72), Expect = 0.83
Identities = 25/76 (32%), Positives = 33/76 (43%)
Frame = +1
Query: 349 SGFGVLGSLSDTLAPGLQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DS 528
+G G SL A + G + E S D+F+PS D + AL A E P S
Sbjct: 136 AGEGQCPSLEPQEAVPVLGSTCFLEEASSDQFLPSLEDPLAGMSALAAAAELPQARPLPS 195
Query: 529 PTSTGRQIERVLEVAK 576
P + G Q LE A+
Sbjct: 196 PGAAGAQALEKLEAAE 211
>AB058759-1|BAB47485.1| 1134|Homo sapiens KIAA1856 protein protein.
Length = 1134
Score = 33.1 bits (72), Expect = 0.83
Identities = 25/76 (32%), Positives = 33/76 (43%)
Frame = +1
Query: 349 SGFGVLGSLSDTLAPGLQGGRRPVPEDSEDKFIPSAVDYVDTWGALEALVEKGPPAP*DS 528
+G G SL A + G + E S D+F+PS D + AL A E P S
Sbjct: 178 AGEGQCPSLEPQEAVPVLGSTCFLEEASSDQFLPSLEDPLAGMNALAAAAELPQARPLPS 237
Query: 529 PTSTGRQIERVLEVAK 576
P + G Q LE A+
Sbjct: 238 PGAAGAQALEKLEAAE 253
>U72619-1|AAB61992.1| 22|Homo sapiens aldose reductase protein.
Length = 22
Score = 31.1 bits (67), Expect = 3.4
Identities = 10/18 (55%), Positives = 14/18 (77%)
Frame = +3
Query: 66 VIFNNGRTCPVIGLGTWK 119
++ NNG P++GLGTWK
Sbjct: 5 LLLNNGAKMPILGLGTWK 22
>U60819-1|AAB39829.1| 685|Homo sapiens rBAT protein.
Length = 685
Score = 30.7 bits (66), Expect = 4.5
Identities = 17/47 (36%), Positives = 24/47 (51%)
Frame = +1
Query: 232 EPSLKKENQKRGYLHNVQVMVHVPPP*SRGGSYQDLVKESGFGVLGS 372
E S+K G++HN ++ P P GS D +K S G+LGS
Sbjct: 12 EMSMKGCQTNNGFVHNEDILEQTPDP----GSSTDNLKHSTRGILGS 54
>M95548-1|AAA35500.1| 685|Homo sapiens amino acid transport protein
protein.
Length = 685
Score = 30.7 bits (66), Expect = 4.5
Identities = 17/47 (36%), Positives = 24/47 (51%)
Frame = +1
Query: 232 EPSLKKENQKRGYLHNVQVMVHVPPP*SRGGSYQDLVKESGFGVLGS 372
E S+K G++HN ++ P P GS D +K S G+LGS
Sbjct: 12 EMSMKGCQTNNGFVHNEDILEQTPDP----GSSTDNLKHSTRGILGS 54
>L11696-1|AAA81778.1| 685|Homo sapiens amino acid transport related
protein protein.
Length = 685
Score = 30.7 bits (66), Expect = 4.5
Identities = 17/47 (36%), Positives = 24/47 (51%)
Frame = +1
Query: 232 EPSLKKENQKRGYLHNVQVMVHVPPP*SRGGSYQDLVKESGFGVLGS 372
E S+K G++HN ++ P P GS D +K S G+LGS
Sbjct: 12 EMSMKGCQTNNGFVHNEDILEQTPDP----GSSTDNLKHSTRGILGS 54
>D87076-1|BAA13245.2| 849|Homo sapiens KIAA0239 protein.
Length = 849
Score = 30.7 bits (66), Expect = 4.5
Identities = 15/33 (45%), Positives = 19/33 (57%)
Frame = +2
Query: 128 RRGDPSSQRRDRYRLPARGLRPHLPQ*EGGGGR 226
R GDP+ + R R RLPA+ P P +G G R
Sbjct: 645 RPGDPARKARGRTRLPAKKKPPPPPPQDGPGSR 677
>D82326-1|BAA11541.1| 685|Homo sapiens Na+-independent neutral and
basic amino acid transporter protein.
Length = 685
Score = 30.7 bits (66), Expect = 4.5
Identities = 17/47 (36%), Positives = 24/47 (51%)
Frame = +1
Query: 232 EPSLKKENQKRGYLHNVQVMVHVPPP*SRGGSYQDLVKESGFGVLGS 372
E S+K G++HN ++ P P GS D +K S G+LGS
Sbjct: 12 EMSMKGCQTNNGFVHNEDILEQTPDP----GSSTDNLKHSTRGILGS 54
>DQ023517-1|AAY89648.1| 551|Homo sapiens SLC3A1 variant G protein.
Length = 551
Score = 30.7 bits (66), Expect = 4.5
Identities = 17/47 (36%), Positives = 24/47 (51%)
Frame = +1
Query: 232 EPSLKKENQKRGYLHNVQVMVHVPPP*SRGGSYQDLVKESGFGVLGS 372
E S+K G++HN ++ P P GS D +K S G+LGS
Sbjct: 12 EMSMKGCQTNNGFVHNEDILEQTPDP----GSSTDNLKHSTRGILGS 54
>DQ023516-1|AAY89647.1| 564|Homo sapiens SLC3A1 variant F protein.
Length = 564
Score = 30.7 bits (66), Expect = 4.5
Identities = 17/47 (36%), Positives = 24/47 (51%)
Frame = +1
Query: 232 EPSLKKENQKRGYLHNVQVMVHVPPP*SRGGSYQDLVKESGFGVLGS 372
E S+K G++HN ++ P P GS D +K S G+LGS
Sbjct: 12 EMSMKGCQTNNGFVHNEDILEQTPDP----GSSTDNLKHSTRGILGS 54
>DQ023515-1|AAY89646.1| 502|Homo sapiens SLC3A1 variant E protein.
Length = 502
Score = 30.7 bits (66), Expect = 4.5
Identities = 17/47 (36%), Positives = 24/47 (51%)
Frame = +1
Query: 232 EPSLKKENQKRGYLHNVQVMVHVPPP*SRGGSYQDLVKESGFGVLGS 372
E S+K G++HN ++ P P GS D +K S G+LGS
Sbjct: 12 EMSMKGCQTNNGFVHNEDILEQTPDP----GSSTDNLKHSTRGILGS 54
>DQ023513-1|AAY89644.1| 391|Homo sapiens SLC3A1 variant C protein.
Length = 391
Score = 30.7 bits (66), Expect = 4.5
Identities = 17/47 (36%), Positives = 24/47 (51%)
Frame = +1
Query: 232 EPSLKKENQKRGYLHNVQVMVHVPPP*SRGGSYQDLVKESGFGVLGS 372
E S+K G++HN ++ P P GS D +K S G+LGS
Sbjct: 12 EMSMKGCQTNNGFVHNEDILEQTPDP----GSSTDNLKHSTRGILGS 54
>BC093626-1|AAH93626.1| 685|Homo sapiens solute carrier family 3,
member 1 protein.
Length = 685
Score = 30.7 bits (66), Expect = 4.5
Identities = 17/47 (36%), Positives = 24/47 (51%)
Frame = +1
Query: 232 EPSLKKENQKRGYLHNVQVMVHVPPP*SRGGSYQDLVKESGFGVLGS 372
E S+K G++HN ++ P P GS D +K S G+LGS
Sbjct: 12 EMSMKGCQTNNGFVHNEDILEQTPDP----GSSTDNLKHSTRGILGS 54
>BC093624-1|AAH93624.1| 685|Homo sapiens solute carrier family 3
(cystine, dibasic and neutral amino acid transporters,
protein.
Length = 685
Score = 30.7 bits (66), Expect = 4.5
Identities = 17/47 (36%), Positives = 24/47 (51%)
Frame = +1
Query: 232 EPSLKKENQKRGYLHNVQVMVHVPPP*SRGGSYQDLVKESGFGVLGS 372
E S+K G++HN ++ P P GS D +K S G+LGS
Sbjct: 12 EMSMKGCQTNNGFVHNEDILEQTPDP----GSSTDNLKHSTRGILGS 54
>BC022386-1|AAH22386.1| 685|Homo sapiens solute carrier family 3
(cystine, dibasic and neutral amino acid transporters,
protein.
Length = 685
Score = 30.7 bits (66), Expect = 4.5
Identities = 17/47 (36%), Positives = 24/47 (51%)
Frame = +1
Query: 232 EPSLKKENQKRGYLHNVQVMVHVPPP*SRGGSYQDLVKESGFGVLGS 372
E S+K G++HN ++ P P GS D +K S G+LGS
Sbjct: 12 EMSMKGCQTNNGFVHNEDILEQTPDP----GSSTDNLKHSTRGILGS 54
>BC021962-1|AAH21962.2| 791|Homo sapiens PHF15 protein protein.
Length = 791
Score = 30.7 bits (66), Expect = 4.5
Identities = 15/33 (45%), Positives = 19/33 (57%)
Frame = +2
Query: 128 RRGDPSSQRRDRYRLPARGLRPHLPQ*EGGGGR 226
R GDP+ + R R RLPA+ P P +G G R
Sbjct: 587 RPGDPARKARGRTRLPAKKKPPPPPPQDGPGSR 619
>BC009307-1|AAH09307.2| 574|Homo sapiens PHF15 protein protein.
Length = 574
Score = 30.7 bits (66), Expect = 4.5
Identities = 15/33 (45%), Positives = 19/33 (57%)
Frame = +2
Query: 128 RRGDPSSQRRDRYRLPARGLRPHLPQ*EGGGGR 226
R GDP+ + R R RLPA+ P P +G G R
Sbjct: 370 RPGDPARKARGRTRLPAKKKPPPPPPQDGPGSR 402
>BC004292-1|AAH04292.1| 246|Homo sapiens PHF15 protein protein.
Length = 246
Score = 30.7 bits (66), Expect = 4.5
Identities = 15/33 (45%), Positives = 19/33 (57%)
Frame = +2
Query: 128 RRGDPSSQRRDRYRLPARGLRPHLPQ*EGGGGR 226
R GDP+ + R R RLPA+ P P +G G R
Sbjct: 42 RPGDPARKARGRTRLPAKKKPPPPPPQDGPGSR 74
>AK223146-1|BAD96866.1| 685|Homo sapiens solute carrier family 3,
member 1 variant protein.
Length = 685
Score = 30.7 bits (66), Expect = 4.5
Identities = 17/47 (36%), Positives = 24/47 (51%)
Frame = +1
Query: 232 EPSLKKENQKRGYLHNVQVMVHVPPP*SRGGSYQDLVKESGFGVLGS 372
E S+K G++HN ++ P P GS D +K S G+LGS
Sbjct: 12 EMSMKGCQTNNGFVHNEDILEQTPDP----GSSTDNLKHSTRGILGS 54
>AJ317974-1|CAC38072.3| 1044|Homo sapiens ataxin-2 related domain
protein protein.
Length = 1044
Score = 30.7 bits (66), Expect = 4.5
Identities = 21/64 (32%), Positives = 31/64 (48%)
Frame = +1
Query: 265 GYLHNVQVMVHVPPP*SRGGSYQDLVKESGFGVLGSLSDTLAPGLQGGRRPVPEDSEDKF 444
G H QVM+ + PP S GG Q V +SG L + + + P + + P P E K
Sbjct: 981 GAPHPPQVML-LHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQAPFPPPGELKI 1039
Query: 445 IPSA 456
+ +A
Sbjct: 1040 VLAA 1043
>AJ251833-1|CAB94935.1| 576|Homo sapiens hypothetical protein
protein.
Length = 576
Score = 30.7 bits (66), Expect = 4.5
Identities = 15/33 (45%), Positives = 19/33 (57%)
Frame = +2
Query: 128 RRGDPSSQRRDRYRLPARGLRPHLPQ*EGGGGR 226
R GDP+ + R R RLPA+ P P +G G R
Sbjct: 372 RPGDPARKARGRTRLPAKKKPPPPPPQDGPGSR 404
>AC013717-2|AAX88955.1| 685|Homo sapiens unknown protein.
Length = 685
Score = 30.7 bits (66), Expect = 4.5
Identities = 17/47 (36%), Positives = 24/47 (51%)
Frame = +1
Query: 232 EPSLKKENQKRGYLHNVQVMVHVPPP*SRGGSYQDLVKESGFGVLGS 372
E S+K G++HN ++ P P GS D +K S G+LGS
Sbjct: 12 EMSMKGCQTNNGFVHNEDILEQTPDP----GSSTDNLKHSTRGILGS 54
>AB033549-1|BAB16841.1| 685|Homo sapiens hrBAT protein.
Length = 685
Score = 30.7 bits (66), Expect = 4.5
Identities = 17/47 (36%), Positives = 24/47 (51%)
Frame = +1
Query: 232 EPSLKKENQKRGYLHNVQVMVHVPPP*SRGGSYQDLVKESGFGVLGS 372
E S+K G++HN ++ P P GS D +K S G+LGS
Sbjct: 12 EMSMKGCQTNNGFVHNEDILEQTPDP----GSSTDNLKHSTRGILGS 54
>BC051787-1|AAH51787.1| 1375|Homo sapiens NLRP1 protein protein.
Length = 1375
Score = 29.9 bits (64), Expect = 7.8
Identities = 12/25 (48%), Positives = 17/25 (68%)
Frame = +1
Query: 187 APTSTSMRRRWGTP*EPSLKKENQK 261
APTST++ WG+P +PSL Q+
Sbjct: 176 APTSTAVLGSWGSPPQPSLAPREQE 200
>BC020956-1|AAH20956.1| 924|Homo sapiens SETD5 protein protein.
Length = 924
Score = 29.9 bits (64), Expect = 7.8
Identities = 19/47 (40%), Positives = 22/47 (46%), Gaps = 2/47 (4%)
Frame = +1
Query: 319 GGSYQDLVKESGFGV--LGSLSDTLAPGLQGGRRPVPEDSEDKFIPS 453
G S Q K +G G S+SDT A G+QG P KF PS
Sbjct: 569 GDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPS 615
>AK025478-1|BAB15144.1| 603|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21825 fis, clone HEP01348. ).
Length = 603
Score = 29.9 bits (64), Expect = 7.8
Identities = 19/47 (40%), Positives = 22/47 (46%), Gaps = 2/47 (4%)
Frame = +1
Query: 319 GGSYQDLVKESGFGV--LGSLSDTLAPGLQGGRRPVPEDSEDKFIPS 453
G S Q K +G G S+SDT A G+QG P KF PS
Sbjct: 248 GDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPS 294
>AK001569-1|BAA91762.1| 924|Homo sapiens protein ( Homo sapiens
cDNA FLJ10707 fis, clone NT2RP3000859. ).
Length = 924
Score = 29.9 bits (64), Expect = 7.8
Identities = 19/47 (40%), Positives = 22/47 (46%), Gaps = 2/47 (4%)
Frame = +1
Query: 319 GGSYQDLVKESGFGV--LGSLSDTLAPGLQGGRRPVPEDSEDKFIPS 453
G S Q K +G G S+SDT A G+QG P KF PS
Sbjct: 569 GDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPS 615
>AF310105-1|AAG30288.1| 1429|Homo sapiens NALP1 protein.
Length = 1429
Score = 29.9 bits (64), Expect = 7.8
Identities = 12/25 (48%), Positives = 17/25 (68%)
Frame = +1
Query: 187 APTSTSMRRRWGTP*EPSLKKENQK 261
APTST++ WG+P +PSL Q+
Sbjct: 176 APTSTAVLGSWGSPPQPSLAPREQE 200
>AF298548-1|AAG15254.1| 1429|Homo sapiens caspase recruitment domain
protein 7 protein.
Length = 1429
Score = 29.9 bits (64), Expect = 7.8
Identities = 12/25 (48%), Positives = 17/25 (68%)
Frame = +1
Query: 187 APTSTSMRRRWGTP*EPSLKKENQK 261
APTST++ WG+P +PSL Q+
Sbjct: 176 APTSTAVLGSWGSPPQPSLAPREQE 200
>AF229062-1|AAK00751.1| 1443|Homo sapiens NAC-delta splice variant
protein.
Length = 1443
Score = 29.9 bits (64), Expect = 7.8
Identities = 12/25 (48%), Positives = 17/25 (68%)
Frame = +1
Query: 187 APTSTSMRRRWGTP*EPSLKKENQK 261
APTST++ WG+P +PSL Q+
Sbjct: 176 APTSTAVLGSWGSPPQPSLAPREQE 200
>AF229061-1|AAK00750.1| 1399|Homo sapiens NAC-gamma splice variant
protein.
Length = 1399
Score = 29.9 bits (64), Expect = 7.8
Identities = 12/25 (48%), Positives = 17/25 (68%)
Frame = +1
Query: 187 APTSTSMRRRWGTP*EPSLKKENQK 261
APTST++ WG+P +PSL Q+
Sbjct: 176 APTSTAVLGSWGSPPQPSLAPREQE 200
>AF229060-1|AAK00749.1| 1473|Homo sapiens NAC-beta splice variant
protein.
Length = 1473
Score = 29.9 bits (64), Expect = 7.8
Identities = 12/25 (48%), Positives = 17/25 (68%)
Frame = +1
Query: 187 APTSTSMRRRWGTP*EPSLKKENQK 261
APTST++ WG+P +PSL Q+
Sbjct: 176 APTSTAVLGSWGSPPQPSLAPREQE 200
>AF229059-1|AAK00748.1| 1429|Homo sapiens NAC-alpha splice variant
protein.
Length = 1429
Score = 29.9 bits (64), Expect = 7.8
Identities = 12/25 (48%), Positives = 17/25 (68%)
Frame = +1
Query: 187 APTSTSMRRRWGTP*EPSLKKENQK 261
APTST++ WG+P +PSL Q+
Sbjct: 176 APTSTAVLGSWGSPPQPSLAPREQE 200
>AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde
reductase AFAR protein.
Length = 330
Score = 29.9 bits (64), Expect = 7.8
Identities = 12/29 (41%), Positives = 18/29 (62%)
Frame = +2
Query: 305 RPDLVEEAIKTSLKNLGLEYLDLYLIHWP 391
+PD V ++TSLK L +DL+ +H P
Sbjct: 86 KPDSVRSQLETSLKRLQCPQVDLFYLHTP 114
>AB051544-1|BAB21848.1| 1409|Homo sapiens KIAA1757 protein protein.
Length = 1409
Score = 29.9 bits (64), Expect = 7.8
Identities = 19/47 (40%), Positives = 22/47 (46%), Gaps = 2/47 (4%)
Frame = +1
Query: 319 GGSYQDLVKESGFGV--LGSLSDTLAPGLQGGRRPVPEDSEDKFIPS 453
G S Q K +G G S+SDT A G+QG P KF PS
Sbjct: 1054 GDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPS 1100
>AB023143-1|BAA76770.2| 1447|Homo sapiens KIAA0926 protein protein.
Length = 1447
Score = 29.9 bits (64), Expect = 7.8
Identities = 12/25 (48%), Positives = 17/25 (68%)
Frame = +1
Query: 187 APTSTSMRRRWGTP*EPSLKKENQK 261
APTST++ WG+P +PSL Q+
Sbjct: 194 APTSTAVLGSWGSPPQPSLAPREQE 218
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 98,843,034
Number of Sequences: 237096
Number of extensions: 2266471
Number of successful extensions: 6172
Number of sequences better than 10.0: 127
Number of HSP's better than 10.0 without gapping: 5588
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6110
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6860268620
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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