Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= e96h0679
(658 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 92 2e-18
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 92 2e-18
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 92 2e-18
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 92 2e-18
BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 79 2e-14
AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 79 2e-14
AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 79 2e-14
AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 79 2e-14
AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 79 2e-14
U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 78 2e-14
D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 78 2e-14
BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 78 2e-14
BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 78 2e-14
AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 78 2e-14
AF221943-1|AAF86378.1| 175|Homo sapiens leukotriene B4 omega hy... 78 2e-14
AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 78 2e-14
AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 78 2e-14
AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 78 2e-14
BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family... 77 4e-14
AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. 77 6e-14
D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV prot... 74 4e-13
D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV prot... 74 4e-13
AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family... 74 4e-13
AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hy... 74 4e-13
AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hy... 74 4e-13
BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family... 73 9e-13
BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family... 73 9e-13
BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family... 73 9e-13
BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 73 9e-13
AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 73 9e-13
AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 71 3e-12
AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens ... 71 4e-12
AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 65 2e-10
BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein. 65 2e-10
AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K p... 65 2e-10
S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxyl... 64 4e-10
S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxyl... 64 4e-10
L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. 64 4e-10
D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxy... 64 4e-10
D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxyl... 64 4e-10
BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. 64 4e-10
BC022851-1|AAH22851.1| 215|Homo sapiens CYP4A11 protein protein. 64 4e-10
AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family... 64 4e-10
AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family... 64 4e-10
AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family... 64 4e-10
AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfam... 64 4e-10
X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for ... 62 1e-09
DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family... 62 1e-09
BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family... 62 1e-09
AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P4... 62 1e-09
AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. 62 1e-09
AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. 62 1e-09
AY064484-1|AAL57719.1| 295|Homo sapiens truncated cytochrome P4... 62 1e-09
AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family... 62 1e-09
AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family... 62 1e-09
AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family... 62 1e-09
AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family... 62 1e-09
AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. 62 1e-09
BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein. 62 2e-09
J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cyto... 61 4e-09
AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 61 4e-09
AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, famil... 61 4e-09
AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family... 61 4e-09
AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 60 9e-09
AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. 57 6e-08
AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. 57 6e-08
AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family... 57 6e-08
AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family... 57 6e-08
AY696295-1|AAU10524.1| 292|Homo sapiens cytochrome P450 protein. 56 8e-08
AK097373-1|BAC05026.1| 340|Homo sapiens protein ( Homo sapiens ... 56 1e-07
BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 55 2e-07
AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 55 2e-07
AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 55 2e-07
AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 55 2e-07
AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 55 2e-07
AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens ... 52 1e-06
AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 52 1e-06
AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P4... 47 5e-05
AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family... 47 5e-05
AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family... 47 5e-05
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 44 5e-04
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 44 5e-04
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 44 5e-04
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 44 6e-04
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 43 8e-04
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 43 8e-04
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 43 8e-04
EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1 var... 43 8e-04
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 43 8e-04
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 43 8e-04
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 43 8e-04
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 43 8e-04
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 43 8e-04
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 43 8e-04
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 43 8e-04
J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 42 0.003
J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 42 0.003
DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 42 0.003
DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 42 0.003
BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 42 0.003
AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 42 0.003
AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 42 0.003
U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 41 0.004
U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 41 0.004
M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 40 0.008
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 40 0.008
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 40 0.008
L16880-1|AAD13466.1| 273|Homo sapiens cytochrome P-450 2C protein. 40 0.008
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 40 0.008
EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1 var... 40 0.008
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 40 0.008
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 40 0.008
BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein. 40 0.008
BC070317-1|AAH70317.1| 162|Homo sapiens CYP2C9 protein protein. 40 0.008
BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 40 0.008
BC020754-1|AAH20754.1| 162|Homo sapiens CYP2C9 protein protein. 40 0.008
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 40 0.008
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 40 0.008
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 40 0.008
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 40 0.008
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 40 0.010
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 40 0.010
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 40 0.010
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 40 0.010
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 40 0.010
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 40 0.010
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 40 0.010
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 40 0.010
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 40 0.010
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 40 0.010
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 40 0.010
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 40 0.010
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 40 0.010
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 40 0.010
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 40 0.010
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 40 0.010
S63426-1|ABB76283.1| 214|Homo sapiens (S)-mephenytoin hydroxyla... 39 0.014
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 39 0.014
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 39 0.014
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 39 0.014
BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein. 39 0.014
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 39 0.014
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 39 0.014
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 39 0.014
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 39 0.014
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 39 0.018
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 38 0.024
AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1 pro... 38 0.024
AY513607-1|AAR90938.1| 100|Homo sapiens truncated cytochrome P4... 38 0.032
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 37 0.055
M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein. 37 0.055
L39098-1|AAL31347.1| 160|Homo sapiens S-mephenytoin 4-hydroxyla... 37 0.055
BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein. 37 0.055
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 37 0.055
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 37 0.055
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 37 0.055
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 37 0.073
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 36 0.13
M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrom... 36 0.13
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 36 0.13
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 36 0.13
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 36 0.13
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 35 0.22
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 35 0.22
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 35 0.22
DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P4... 35 0.22
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 35 0.22
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 35 0.22
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 35 0.22
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 35 0.22
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 35 0.22
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 35 0.22
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 34 0.39
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 34 0.39
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 34 0.39
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 34 0.39
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 34 0.39
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 34 0.39
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 32 1.6
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 32 1.6
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 32 1.6
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 32 1.6
M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 32 2.1
BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family... 32 2.1
X54807-1|CAA38578.1| 56|Homo sapiens unspecific monooxygenase ... 31 4.8
BC139737-1|AAI39738.1| 263|Homo sapiens transmembrane protein 5... 31 4.8
BC004367-1|AAH04367.1| 313|Homo sapiens potassium channel, subf... 31 4.8
AK222545-1|BAD96265.1| 313|Homo sapiens potassium channel, subf... 31 4.8
AK056404-1|BAB71177.1| 263|Homo sapiens protein ( Homo sapiens ... 31 4.8
AJ297404-1|CAC15489.1| 313|Homo sapiens potassium channel, subf... 31 4.8
AF281303-1|AAG10507.1| 179|Homo sapiens 2P domain K+ channel TW... 31 4.8
AF281302-1|AAG10506.1| 313|Homo sapiens 2P domain K+ channel TW... 31 4.8
AF134149-1|AAD22980.1| 313|Homo sapiens 2-pore K+ channel subun... 31 4.8
AF117708-1|AAD24000.1| 313|Homo sapiens tandem pore domain pota... 31 4.8
AK024290-1|BAB14875.1| 590|Homo sapiens protein ( Homo sapiens ... 30 6.3
AB040956-1|BAA96047.1| 687|Homo sapiens KIAA1523 protein protein. 30 6.3
DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6 pro... 30 8.3
AF280107-4|AAG32288.1| 106|Homo sapiens cytochrome P450 polypep... 30 8.3
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 91.9 bits (218), Expect = 2e-18
Identities = 53/135 (39%), Positives = 80/135 (59%), Gaps = 9/135 (6%)
Frame = +2
Query: 266 VVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHXX 445
++++W+G +V L +A+++E+IL S IDK++ YKF +PWLG GLL S+G KWRS
Sbjct: 89 LLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRK 148
Query: 446 MIAPTFHINILKSFVGIFNQNVTTW*RS*NLKSEKHLT-------YMIT*VVPQLIFLLE 604
M+ PTFH IL+ F+ I N+ + K EKH+ + IT + L + E
Sbjct: 149 MLTPTFHFTILEDFLDIMNEQANILVK----KLEKHINQEAFNCFFYIT--LCALDIICE 202
Query: 605 TAMG--ISRKTQDES 643
TAMG I ++ D+S
Sbjct: 203 TAMGKNIGAQSNDDS 217
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 91.9 bits (218), Expect = 2e-18
Identities = 53/135 (39%), Positives = 80/135 (59%), Gaps = 9/135 (6%)
Frame = +2
Query: 266 VVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHXX 445
++++W+G +V L +A+++E+IL S IDK++ YKF +PWLG GLL S+G KWRS
Sbjct: 89 LLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRK 148
Query: 446 MIAPTFHINILKSFVGIFNQNVTTW*RS*NLKSEKHLT-------YMIT*VVPQLIFLLE 604
M+ PTFH IL+ F+ I N+ + K EKH+ + IT + L + E
Sbjct: 149 MLTPTFHFTILEDFLDIMNEQANILVK----KLEKHINQEAFNCFFYIT--LCALDIICE 202
Query: 605 TAMG--ISRKTQDES 643
TAMG I ++ D+S
Sbjct: 203 TAMGKNIGAQSNDDS 217
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 91.9 bits (218), Expect = 2e-18
Identities = 53/135 (39%), Positives = 80/135 (59%), Gaps = 9/135 (6%)
Frame = +2
Query: 266 VVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHXX 445
++++W+G +V L +A+++E+IL S IDK++ YKF +PWLG GLL S+G KWRS
Sbjct: 67 LLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRK 126
Query: 446 MIAPTFHINILKSFVGIFNQNVTTW*RS*NLKSEKHLT-------YMIT*VVPQLIFLLE 604
M+ PTFH IL+ F+ I N+ + K EKH+ + IT + L + E
Sbjct: 127 MLTPTFHFTILEDFLDIMNEQANILVK----KLEKHINQEAFNCFFYIT--LCALDIICE 180
Query: 605 TAMG--ISRKTQDES 643
TAMG I ++ D+S
Sbjct: 181 TAMGKNIGAQSNDDS 195
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 91.9 bits (218), Expect = 2e-18
Identities = 53/135 (39%), Positives = 80/135 (59%), Gaps = 9/135 (6%)
Frame = +2
Query: 266 VVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHXX 445
++++W+G +V L +A+++E+IL S IDK++ YKF +PWLG GLL S+G KWRS
Sbjct: 89 LLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRK 148
Query: 446 MIAPTFHINILKSFVGIFNQNVTTW*RS*NLKSEKHLT-------YMIT*VVPQLIFLLE 604
M+ PTFH IL+ F+ I N+ + K EKH+ + IT + L + E
Sbjct: 149 MLTPTFHFTILEDFLDIMNEQANILVK----KLEKHINQEAFNCFFYIT--LCALDIICE 202
Query: 605 TAMG--ISRKTQDES 643
TAMG I ++ D+S
Sbjct: 203 TAMGKNIGAQSNDDS 217
>BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 12 protein.
Length = 524
Score = 78.6 bits (185), Expect = 2e-14
Identities = 38/91 (41%), Positives = 51/91 (56%), Gaps = 3/91 (3%)
Frame = +2
Query: 245 LCATFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLLIS 415
+ AT+ VWLG + + L D I I N+ I +F KPWLGEG+L+S
Sbjct: 80 MSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLS 139
Query: 416 SGPKWRSHXXMIAPTFHINILKSFVGIFNQN 508
G KW H M+ P FH NILKS++ IFN++
Sbjct: 140 GGDKWSRHRRMLTPAFHFNILKSYITIFNKS 170
>AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein.
Length = 524
Score = 78.6 bits (185), Expect = 2e-14
Identities = 38/91 (41%), Positives = 51/91 (56%), Gaps = 3/91 (3%)
Frame = +2
Query: 245 LCATFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLLIS 415
+ AT+ VWLG + + L D I I N+ I +F KPWLGEG+L+S
Sbjct: 80 MSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLS 139
Query: 416 SGPKWRSHXXMIAPTFHINILKSFVGIFNQN 508
G KW H M+ P FH NILKS++ IFN++
Sbjct: 140 GGDKWSRHRRMLTPAFHFNILKSYITIFNKS 170
>AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform
4F12 protein.
Length = 524
Score = 78.6 bits (185), Expect = 2e-14
Identities = 38/91 (41%), Positives = 51/91 (56%), Gaps = 3/91 (3%)
Frame = +2
Query: 245 LCATFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLLIS 415
+ AT+ VWLG + + L D I I N+ I +F KPWLGEG+L+S
Sbjct: 80 MSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLS 139
Query: 416 SGPKWRSHXXMIAPTFHINILKSFVGIFNQN 508
G KW H M+ P FH NILKS++ IFN++
Sbjct: 140 GGDKWSRHRRMLTPAFHFNILKSYITIFNKS 170
>AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 78.6 bits (185), Expect = 2e-14
Identities = 38/91 (41%), Positives = 51/91 (56%), Gaps = 3/91 (3%)
Frame = +2
Query: 245 LCATFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLLIS 415
+ AT+ VWLG + + L D I I N+ I +F KPWLGEG+L+S
Sbjct: 80 MSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLS 139
Query: 416 SGPKWRSHXXMIAPTFHINILKSFVGIFNQN 508
G KW H M+ P FH NILKS++ IFN++
Sbjct: 140 GGDKWSRHRRMLTPAFHFNILKSYITIFNKS 170
>AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 78.6 bits (185), Expect = 2e-14
Identities = 38/91 (41%), Positives = 51/91 (56%), Gaps = 3/91 (3%)
Frame = +2
Query: 245 LCATFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLLIS 415
+ AT+ VWLG + + L D I I N+ I +F KPWLGEG+L+S
Sbjct: 80 MSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLS 139
Query: 416 SGPKWRSHXXMIAPTFHINILKSFVGIFNQN 508
G KW H M+ P FH NILKS++ IFN++
Sbjct: 140 GGDKWSRHRRMLTPAFHFNILKSYITIFNKS 170
>U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein.
Length = 520
Score = 78.2 bits (184), Expect = 2e-14
Identities = 37/92 (40%), Positives = 55/92 (59%), Gaps = 3/92 (3%)
Frame = +2
Query: 245 LCATFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHIDKATE--YKFFKPWLGEGLLIS 415
L AT+ +VW+G ++ L D I ++N+ I + Y F +PWLG+GLL+S
Sbjct: 80 LVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLS 139
Query: 416 SGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
+G KW H M+ P FH NILK ++ IFN++V
Sbjct: 140 AGDKWSRHRRMLTPAFHFNILKPYMKIFNESV 171
>D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 78.2 bits (184), Expect = 2e-14
Identities = 37/92 (40%), Positives = 55/92 (59%), Gaps = 3/92 (3%)
Frame = +2
Query: 245 LCATFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHIDKATE--YKFFKPWLGEGLLIS 415
L AT+ +VW+G ++ L D I ++N+ I + Y F +PWLG+GLL+S
Sbjct: 80 LVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLS 139
Query: 416 SGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
+G KW H M+ P FH NILK ++ IFN++V
Sbjct: 140 AGDKWSRHRRMLTPAFHFNILKPYMKIFNESV 171
>BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 78.2 bits (184), Expect = 2e-14
Identities = 37/92 (40%), Positives = 55/92 (59%), Gaps = 3/92 (3%)
Frame = +2
Query: 245 LCATFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHIDKATE--YKFFKPWLGEGLLIS 415
L AT+ +VW+G ++ L D I ++N+ I + Y F +PWLG+GLL+S
Sbjct: 80 LVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLS 139
Query: 416 SGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
+G KW H M+ P FH NILK ++ IFN++V
Sbjct: 140 AGDKWSRHRRMLTPAFHFNILKPYMKIFNESV 171
>BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 78.2 bits (184), Expect = 2e-14
Identities = 37/92 (40%), Positives = 55/92 (59%), Gaps = 3/92 (3%)
Frame = +2
Query: 245 LCATFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHIDKATE--YKFFKPWLGEGLLIS 415
L AT+ +VW+G ++ L D I ++N+ I + Y F +PWLG+GLL+S
Sbjct: 80 LVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLS 139
Query: 416 SGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
+G KW H M+ P FH NILK ++ IFN++V
Sbjct: 140 AGDKWSRHRRMLTPAFHFNILKPYMKIFNESV 171
>AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfamily
IVF, polypeptide 2 protein.
Length = 520
Score = 78.2 bits (184), Expect = 2e-14
Identities = 37/92 (40%), Positives = 55/92 (59%), Gaps = 3/92 (3%)
Frame = +2
Query: 245 LCATFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHIDKATE--YKFFKPWLGEGLLIS 415
L AT+ +VW+G ++ L D I ++N+ I + Y F +PWLG+GLL+S
Sbjct: 80 LVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLS 139
Query: 416 SGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
+G KW H M+ P FH NILK ++ IFN++V
Sbjct: 140 AGDKWSRHRRMLTPAFHFNILKPYMKIFNESV 171
>AF221943-1|AAF86378.1| 175|Homo sapiens leukotriene B4 omega
hydroxylase protein.
Length = 175
Score = 78.2 bits (184), Expect = 2e-14
Identities = 37/92 (40%), Positives = 55/92 (59%), Gaps = 3/92 (3%)
Frame = +2
Query: 245 LCATFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHIDKATE--YKFFKPWLGEGLLIS 415
L AT+ +VW+G ++ L D I ++N+ I + Y F +PWLG+GLL+S
Sbjct: 80 LVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLS 139
Query: 416 SGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
+G KW H M+ P FH NILK ++ IFN++V
Sbjct: 140 AGDKWSRHRRMLTPAFHFNILKPYMKIFNESV 171
>AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein.
Length = 520
Score = 78.2 bits (184), Expect = 2e-14
Identities = 37/92 (40%), Positives = 55/92 (59%), Gaps = 3/92 (3%)
Frame = +2
Query: 245 LCATFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHIDKATE--YKFFKPWLGEGLLIS 415
L AT+ +VW+G ++ L D I ++N+ I + Y F +PWLG+GLL+S
Sbjct: 80 LVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLS 139
Query: 416 SGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
+G KW H M+ P FH NILK ++ IFN++V
Sbjct: 140 AGDKWSRHRRMLTPAFHFNILKPYMKIFNESV 171
>AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein.
Length = 458
Score = 78.2 bits (184), Expect = 2e-14
Identities = 37/91 (40%), Positives = 51/91 (56%), Gaps = 3/91 (3%)
Frame = +2
Query: 245 LCATFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLLIS 415
+ AT+ +WLG + + L D I I N+ I +F KPWLGEG+L+S
Sbjct: 14 MSATYSQGFTIWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLS 73
Query: 416 SGPKWRSHXXMIAPTFHINILKSFVGIFNQN 508
G KW H M+ P FH NILKS++ IFN++
Sbjct: 74 GGDKWSRHRRMLTPAFHFNILKSYITIFNKS 104
>AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 78.2 bits (184), Expect = 2e-14
Identities = 37/92 (40%), Positives = 55/92 (59%), Gaps = 3/92 (3%)
Frame = +2
Query: 245 LCATFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHIDKATE--YKFFKPWLGEGLLIS 415
L AT+ +VW+G ++ L D I ++N+ I + Y F +PWLG+GLL+S
Sbjct: 80 LVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLS 139
Query: 416 SGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
+G KW H M+ P FH NILK ++ IFN++V
Sbjct: 140 AGDKWSRHRRMLTPAFHFNILKPYMKIFNESV 171
>BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 77.4 bits (182), Expect = 4e-14
Identities = 37/92 (40%), Positives = 54/92 (58%), Gaps = 3/92 (3%)
Frame = +2
Query: 245 LCATFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHIDKATE--YKFFKPWLGEGLLIS 415
L AT+ +VW+G ++ L D I ++N+ I + Y F +PWLG+GLL+S
Sbjct: 80 LVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLS 139
Query: 416 SGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
+G KW H M+ P FH NILK ++ IFN +V
Sbjct: 140 AGDKWSRHRRMLTPAFHFNILKPYMKIFNDSV 171
>AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein.
Length = 520
Score = 77.0 bits (181), Expect = 6e-14
Identities = 38/93 (40%), Positives = 55/93 (59%), Gaps = 4/93 (4%)
Frame = +2
Query: 245 LCATFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHI---DKATEYKFFKPWLGEGLLI 412
L AT+ +VW+G ++ + I ++N+ I DK Y F KPWLG+GLL+
Sbjct: 80 LVATYPQGFKVWMGPIFPVIRFCHPNIIRSVINASAAIVPKDKVF-YSFLKPWLGDGLLL 138
Query: 413 SSGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
S+G KW H M+ P FH NILK ++ IFN++V
Sbjct: 139 SAGEKWSRHRRMLTPAFHFNILKPYMKIFNESV 171
>D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV
protein.
Length = 389
Score = 74.1 bits (174), Expect = 4e-13
Identities = 40/93 (43%), Positives = 55/93 (59%), Gaps = 4/93 (4%)
Frame = +2
Query: 245 LCATFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHI---DKATEYKFFKPWLGEGLLI 412
L TFG++ W+G IV + I+ +L + I DK Y F KPWLG+GLL+
Sbjct: 80 LACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVF-YSFLKPWLGDGLLL 138
Query: 413 SSGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
S+G KW H M+ P FH NILK ++ IFN++V
Sbjct: 139 SAGEKWSRHRRMLTPAFHFNILKPYMKIFNESV 171
>D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV
protein.
Length = 520
Score = 74.1 bits (174), Expect = 4e-13
Identities = 40/93 (43%), Positives = 55/93 (59%), Gaps = 4/93 (4%)
Frame = +2
Query: 245 LCATFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHI---DKATEYKFFKPWLGEGLLI 412
L TFG++ W+G IV + I+ +L + I DK Y F KPWLG+GLL+
Sbjct: 80 LACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVF-YSFLKPWLGDGLLL 138
Query: 413 SSGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
S+G KW H M+ P FH NILK ++ IFN++V
Sbjct: 139 SAGEKWSRHRRMLTPAFHFNILKPYMKIFNESV 171
>AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 3 protein.
Length = 520
Score = 74.1 bits (174), Expect = 4e-13
Identities = 40/93 (43%), Positives = 55/93 (59%), Gaps = 4/93 (4%)
Frame = +2
Query: 245 LCATFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHI---DKATEYKFFKPWLGEGLLI 412
L TFG++ W+G IV + I+ +L + I DK Y F KPWLG+GLL+
Sbjct: 80 LACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVF-YSFLKPWLGDGLLL 138
Query: 413 SSGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
S+G KW H M+ P FH NILK ++ IFN++V
Sbjct: 139 SAGEKWSRHRRMLTPAFHFNILKPYMKIFNESV 171
>AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 74.1 bits (174), Expect = 4e-13
Identities = 40/93 (43%), Positives = 55/93 (59%), Gaps = 4/93 (4%)
Frame = +2
Query: 245 LCATFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHI---DKATEYKFFKPWLGEGLLI 412
L TFG++ W+G IV + I+ +L + I DK Y F KPWLG+GLL+
Sbjct: 80 LACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVF-YSFLKPWLGDGLLL 138
Query: 413 SSGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
S+G KW H M+ P FH NILK ++ IFN++V
Sbjct: 139 SAGEKWSRHRRMLTPAFHFNILKPYMKIFNESV 171
>AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 74.1 bits (174), Expect = 4e-13
Identities = 40/93 (43%), Positives = 55/93 (59%), Gaps = 4/93 (4%)
Frame = +2
Query: 245 LCATFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHI---DKATEYKFFKPWLGEGLLI 412
L TFG++ W+G IV + I+ +L + I DK Y F KPWLG+GLL+
Sbjct: 80 LACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVF-YSFLKPWLGDGLLL 138
Query: 413 SSGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
S+G KW H M+ P FH NILK ++ IFN++V
Sbjct: 139 SAGEKWSRHRRMLTPAFHFNILKPYMKIFNESV 171
>BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 72.9 bits (171), Expect = 9e-13
Identities = 35/85 (41%), Positives = 52/85 (61%), Gaps = 3/85 (3%)
Frame = +2
Query: 263 NVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATE--YKFFKPWLGEGLLISSGPKWR 433
+V+ VW+G L ++ L D I+ +L + I + Y F KPWLG+GLL+S G KW
Sbjct: 94 HVLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGLLLSKGDKWS 153
Query: 434 SHXXMIAPTFHINILKSFVGIFNQN 508
H ++ P FH +ILK ++ IFNQ+
Sbjct: 154 RHRRLLTPAFHFDILKPYMKIFNQS 178
>BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 72.9 bits (171), Expect = 9e-13
Identities = 35/85 (41%), Positives = 52/85 (61%), Gaps = 3/85 (3%)
Frame = +2
Query: 263 NVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATE--YKFFKPWLGEGLLISSGPKWR 433
+V+ VW+G L ++ L D I+ +L + I + Y F KPWLG+GLL+S G KW
Sbjct: 94 HVLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGLLLSKGDKWS 153
Query: 434 SHXXMIAPTFHINILKSFVGIFNQN 508
H ++ P FH +ILK ++ IFNQ+
Sbjct: 154 RHRRLLTPAFHFDILKPYMKIFNQS 178
>BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 72.9 bits (171), Expect = 9e-13
Identities = 35/85 (41%), Positives = 52/85 (61%), Gaps = 3/85 (3%)
Frame = +2
Query: 263 NVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATE--YKFFKPWLGEGLLISSGPKWR 433
+V+ VW+G L ++ L D I+ +L + I + Y F KPWLG+GLL+S G KW
Sbjct: 94 HVLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGLLLSKGDKWS 153
Query: 434 SHXXMIAPTFHINILKSFVGIFNQN 508
H ++ P FH +ILK ++ IFNQ+
Sbjct: 154 RHRRLLTPAFHFDILKPYMKIFNQS 178
>BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein.
Length = 524
Score = 72.9 bits (171), Expect = 9e-13
Identities = 36/92 (39%), Positives = 51/92 (55%), Gaps = 3/92 (3%)
Frame = +2
Query: 245 LCATFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATE--YKFFKPWLGEGLLIS 415
L T+ ++WLG ++ L D I I ++ + Y F KPWLG+GLL+S
Sbjct: 80 LVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGLLLS 139
Query: 416 SGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
G KW H M+ P FH NILK ++ IFN++V
Sbjct: 140 GGDKWSRHRRMLTPAFHFNILKPYMKIFNKSV 171
>AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein.
Length = 524
Score = 72.9 bits (171), Expect = 9e-13
Identities = 36/92 (39%), Positives = 51/92 (55%), Gaps = 3/92 (3%)
Frame = +2
Query: 245 LCATFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATE--YKFFKPWLGEGLLIS 415
L T+ ++WLG ++ L D I I ++ + Y F KPWLG+GLL+S
Sbjct: 80 LVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGLLLS 139
Query: 416 SGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
G KW H M+ P FH NILK ++ IFN++V
Sbjct: 140 GGDKWSRHRRMLTPAFHFNILKPYMKIFNKSV 171
>AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein.
Length = 520
Score = 71.3 bits (167), Expect = 3e-12
Identities = 38/91 (41%), Positives = 53/91 (58%), Gaps = 3/91 (3%)
Frame = +2
Query: 245 LCATFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHI-DK-ATEYKFFKPWLGEGLLIS 415
L AT+ WLG I+ L D + ++N+ I DK YK KPWLG+GLL+S
Sbjct: 80 LVATYPQGFVRWLGPITPIINLCHPDIVRSVINTSDAITDKDIVFYKTLKPWLGDGLLLS 139
Query: 416 SGPKWRSHXXMIAPTFHINILKSFVGIFNQN 508
G KWR H ++ P FH NILK ++ IF+++
Sbjct: 140 VGDKWRHHRRLLTPAFHFNILKPYIKIFSKS 170
>AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ39501 fis, clone PROST2016980, moderately
similar to CYTOCHROME P450 4F2 (EC 1.14.13.30). ).
Length = 531
Score = 70.9 bits (166), Expect = 4e-12
Identities = 34/85 (40%), Positives = 51/85 (60%), Gaps = 3/85 (3%)
Frame = +2
Query: 263 NVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATE--YKFFKPWLGEGLLISSGPKWR 433
+V+ VW+G L ++ L D I+ +L + + Y F KPWLG+GLL+S G KW
Sbjct: 94 HVLLVWMGPVLPLLVLVHPDYIKPLLGASAATAPKDDLFYGFLKPWLGDGLLLSKGDKWS 153
Query: 434 SHXXMIAPTFHINILKSFVGIFNQN 508
H ++ P FH +ILK ++ IFNQ+
Sbjct: 154 RHRRLLTPAFHFDILKPYMKIFNQS 178
>AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22
protein.
Length = 519
Score = 65.3 bits (152), Expect = 2e-10
Identities = 46/156 (29%), Positives = 74/156 (47%), Gaps = 2/156 (1%)
Frame = +2
Query: 50 VNSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTX-HEEKSPRI 226
V S +I LL +++ +W + K + P P +FG+ H+++ RI
Sbjct: 21 VTSLLILLLLLIKAAQLYLHRQW-----LLKALQQFPCPPSHWLFGHIQEFQHDQELQRI 75
Query: 227 SQPRSGLCATFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEG 403
+ TF + W+ G K+ V L D D +++IL + YKF PW+G
Sbjct: 76 QER----VKTFPSACPYWIWGGKVRVQLYDPDYMKVILGRSDSKSHGS-YKFLAPWIGYS 130
Query: 404 LLISSGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
LL+ +G W H M+ P FH +ILK +VG+ +V
Sbjct: 131 LLLLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSV 166
>BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein.
Length = 455
Score = 64.9 bits (151), Expect = 2e-10
Identities = 46/156 (29%), Positives = 74/156 (47%), Gaps = 2/156 (1%)
Frame = +2
Query: 50 VNSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTX-HEEKSPRI 226
V S +I LL +++ +W + K + P P +FG+ H+++ RI
Sbjct: 21 VTSLLILLLLLIKAAQLYLHRQW-----LLKALQQFPCPPSHWLFGHIQEFQHDQELQRI 75
Query: 227 SQPRSGLCATFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEG 403
+ TF + W+ G K+ V L D D +++IL + YKF PW+G
Sbjct: 76 QER----VKTFPSACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPWIGYS 130
Query: 404 LLISSGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
LL+ +G W H M+ P FH +ILK +VG+ +V
Sbjct: 131 LLLLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSV 166
>AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K
protein.
Length = 519
Score = 64.9 bits (151), Expect = 2e-10
Identities = 46/156 (29%), Positives = 74/156 (47%), Gaps = 2/156 (1%)
Frame = +2
Query: 50 VNSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTX-HEEKSPRI 226
V S +I LL +++ +W + K + P P +FG+ H+++ RI
Sbjct: 21 VTSLLILLLLLIKAAQLYLHRQW-----LLKALQQFPCPPSHWLFGHIQEFQHDQELQRI 75
Query: 227 SQPRSGLCATFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEG 403
+ TF + W+ G K+ V L D D +++IL + YKF PW+G
Sbjct: 76 QER----VKTFPSACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPWIGYS 130
Query: 404 LLISSGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
LL+ +G W H M+ P FH +ILK +VG+ +V
Sbjct: 131 LLLLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSV 166
>S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 591
Score = 64.1 bits (149), Expect = 4e-10
Identities = 33/87 (37%), Positives = 48/87 (55%), Gaps = 1/87 (1%)
Frame = +2
Query: 254 TFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKW 430
TF + WL G K+ V L D D +++IL + Y+F PW+G GLL+ +G W
Sbjct: 81 TFPSACPHWLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTW 139
Query: 431 RSHXXMIAPTFHINILKSFVGIFNQNV 511
H M+ P FH +ILK +VG+ +V
Sbjct: 140 FQHRRMLTPAFHYDILKPYVGLMADSV 166
>S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 519
Score = 64.1 bits (149), Expect = 4e-10
Identities = 33/87 (37%), Positives = 48/87 (55%), Gaps = 1/87 (1%)
Frame = +2
Query: 254 TFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKW 430
TF + WL G K+ V L D D +++IL + Y+F PW+G GLL+ +G W
Sbjct: 81 TFPSACPHWLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTW 139
Query: 431 RSHXXMIAPTFHINILKSFVGIFNQNV 511
H M+ P FH +ILK +VG+ +V
Sbjct: 140 FQHRRMLTPAFHYDILKPYVGLMADSV 166
>L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein.
Length = 519
Score = 64.1 bits (149), Expect = 4e-10
Identities = 33/87 (37%), Positives = 48/87 (55%), Gaps = 1/87 (1%)
Frame = +2
Query: 254 TFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKW 430
TF + WL G K+ V L D D +++IL + Y+F PW+G GLL+ +G W
Sbjct: 81 TFPSACPHWLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTW 139
Query: 431 RSHXXMIAPTFHINILKSFVGIFNQNV 511
H M+ P FH +ILK +VG+ +V
Sbjct: 140 FQHRRMLTPAFHYDILKPYVGLMADSV 166
>D26481-1|BAA05491.1| 519|Homo sapiens fatty acids
omega-hydroxylase protein.
Length = 519
Score = 64.1 bits (149), Expect = 4e-10
Identities = 33/87 (37%), Positives = 48/87 (55%), Gaps = 1/87 (1%)
Frame = +2
Query: 254 TFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKW 430
TF + WL G K+ V L D D +++IL + Y+F PW+G GLL+ +G W
Sbjct: 81 TFPSACPHWLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTW 139
Query: 431 RSHXXMIAPTFHINILKSFVGIFNQNV 511
H M+ P FH +ILK +VG+ +V
Sbjct: 140 FQHRRMLTPAFHYDILKPYVGLMADSV 166
>D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 521
Score = 64.1 bits (149), Expect = 4e-10
Identities = 33/87 (37%), Positives = 48/87 (55%), Gaps = 1/87 (1%)
Frame = +2
Query: 254 TFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKW 430
TF + WL G K+ V L D D +++IL + Y+F PW+G GLL+ +G W
Sbjct: 81 TFPSACPHWLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTW 139
Query: 431 RSHXXMIAPTFHINILKSFVGIFNQNV 511
H M+ P FH +ILK +VG+ +V
Sbjct: 140 FQHRRMLTPAFHYDILKPYVGLMADSV 166
>BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein.
Length = 455
Score = 64.1 bits (149), Expect = 4e-10
Identities = 33/87 (37%), Positives = 48/87 (55%), Gaps = 1/87 (1%)
Frame = +2
Query: 254 TFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKW 430
TF + WL G K+ V L D D +++IL + Y+F PW+G GLL+ +G W
Sbjct: 81 TFPSACPHWLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTW 139
Query: 431 RSHXXMIAPTFHINILKSFVGIFNQNV 511
H M+ P FH +ILK +VG+ +V
Sbjct: 140 FQHRRMLTPAFHYDILKPYVGLMADSV 166
>BC022851-1|AAH22851.1| 215|Homo sapiens CYP4A11 protein protein.
Length = 215
Score = 64.1 bits (149), Expect = 4e-10
Identities = 33/87 (37%), Positives = 48/87 (55%), Gaps = 1/87 (1%)
Frame = +2
Query: 254 TFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKW 430
TF + WL G K+ V L D D +++IL + Y+F PW+G GLL+ +G W
Sbjct: 81 TFPSACPHWLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTW 139
Query: 431 RSHXXMIAPTFHINILKSFVGIFNQNV 511
H M+ P FH +ILK +VG+ +V
Sbjct: 140 FQHRRMLTPAFHYDILKPYVGLMADSV 166
>AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 64.1 bits (149), Expect = 4e-10
Identities = 33/87 (37%), Positives = 48/87 (55%), Gaps = 1/87 (1%)
Frame = +2
Query: 254 TFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKW 430
TF + WL G K+ V L D D +++IL + Y+F PW+G GLL+ +G W
Sbjct: 81 TFPSACPHWLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTW 139
Query: 431 RSHXXMIAPTFHINILKSFVGIFNQNV 511
H M+ P FH +ILK +VG+ +V
Sbjct: 140 FQHRRMLTPAFHYDILKPYVGLMADSV 166
>AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 455
Score = 64.1 bits (149), Expect = 4e-10
Identities = 33/87 (37%), Positives = 48/87 (55%), Gaps = 1/87 (1%)
Frame = +2
Query: 254 TFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKW 430
TF + WL G K+ V L D D +++IL + Y+F PW+G GLL+ +G W
Sbjct: 81 TFPSACPHWLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTW 139
Query: 431 RSHXXMIAPTFHINILKSFVGIFNQNV 511
H M+ P FH +ILK +VG+ +V
Sbjct: 140 FQHRRMLTPAFHYDILKPYVGLMADSV 166
>AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 64.1 bits (149), Expect = 4e-10
Identities = 33/87 (37%), Positives = 48/87 (55%), Gaps = 1/87 (1%)
Frame = +2
Query: 254 TFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKW 430
TF + WL G K+ V L D D +++IL + Y+F PW+G GLL+ +G W
Sbjct: 81 TFPSACPHWLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTW 139
Query: 431 RSHXXMIAPTFHINILKSFVGIFNQNV 511
H M+ P FH +ILK +VG+ +V
Sbjct: 140 FQHRRMLTPAFHYDILKPYVGLMADSV 166
>AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfamily
IVA, polypeptide 11 protein.
Length = 519
Score = 64.1 bits (149), Expect = 4e-10
Identities = 33/87 (37%), Positives = 48/87 (55%), Gaps = 1/87 (1%)
Frame = +2
Query: 254 TFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKW 430
TF + WL G K+ V L D D +++IL + Y+F PW+G GLL+ +G W
Sbjct: 81 TFPSACPHWLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTW 139
Query: 431 RSHXXMIAPTFHINILKSFVGIFNQNV 511
H M+ P FH +ILK +VG+ +V
Sbjct: 140 FQHRRMLTPAFHYDILKPYVGLMADSV 166
>X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for
cytochrome P-450HP. ).
Length = 511
Score = 62.5 bits (145), Expect = 1e-09
Identities = 42/144 (29%), Positives = 63/144 (43%)
Frame = +2
Query: 77 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCAT 256
+LG I +L R Q + K + PGP +FG+AL E S + + S
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGS--LDKVVSW-AHQ 76
Query: 257 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 436
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 437 HXXMIAPTFHINILKSFVGIFNQN 508
H ++ P FH ++LK +V +F ++
Sbjct: 137 HRKLLTPGFHYDVLKPYVAVFTES 160
>DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 62.5 bits (145), Expect = 1e-09
Identities = 42/144 (29%), Positives = 63/144 (43%)
Frame = +2
Query: 77 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCAT 256
+LG I +L R Q + K + PGP +FG+AL E S + + S
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGS--LDKVVSW-AHQ 76
Query: 257 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 436
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 437 HXXMIAPTFHINILKSFVGIFNQN 508
H ++ P FH ++LK +V +F ++
Sbjct: 137 HRKLLTPGFHYDVLKPYVAVFTES 160
>BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 62.5 bits (145), Expect = 1e-09
Identities = 42/144 (29%), Positives = 63/144 (43%)
Frame = +2
Query: 77 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCAT 256
+LG I +L R Q + K + PGP +FG+AL E S + + S
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGS--LDKVVSW-AHQ 76
Query: 257 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 436
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 437 HXXMIAPTFHINILKSFVGIFNQN 508
H ++ P FH ++LK +V +F ++
Sbjct: 137 HRKLLTPGFHYDVLKPYVAVFTES 160
>AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P450
4B1 protein.
Length = 512
Score = 62.5 bits (145), Expect = 1e-09
Identities = 42/144 (29%), Positives = 63/144 (43%)
Frame = +2
Query: 77 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCAT 256
+LG I +L R Q + K + PGP +FG+AL E S + + S
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGS--LDKVVSW-AHQ 76
Query: 257 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 436
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 437 HXXMIAPTFHINILKSFVGIFNQN 508
H ++ P FH ++LK +V +F ++
Sbjct: 137 HRKLLTPGFHYDVLKPYVAVFTES 160
>AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 62.5 bits (145), Expect = 1e-09
Identities = 42/144 (29%), Positives = 63/144 (43%)
Frame = +2
Query: 77 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCAT 256
+LG I +L R Q + K + PGP +FG+AL E S + + S
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGS--LDKVVSW-AHQ 76
Query: 257 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 436
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 437 HXXMIAPTFHINILKSFVGIFNQN 508
H ++ P FH ++LK +V +F ++
Sbjct: 137 HRKLLTPGFHYDVLKPYVAVFTES 160
>AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 62.5 bits (145), Expect = 1e-09
Identities = 42/144 (29%), Positives = 63/144 (43%)
Frame = +2
Query: 77 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCAT 256
+LG I +L R Q + K + PGP +FG+AL E S + + S
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGS--LDKVVSW-AHQ 76
Query: 257 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 436
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 437 HXXMIAPTFHINILKSFVGIFNQN 508
H ++ P FH ++LK +V +F ++
Sbjct: 137 HRKLLTPGFHYDVLKPYVAVFTES 160
>AY064484-1|AAL57719.1| 295|Homo sapiens truncated cytochrome P450
protein.
Length = 295
Score = 62.5 bits (145), Expect = 1e-09
Identities = 42/144 (29%), Positives = 63/144 (43%)
Frame = +2
Query: 77 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCAT 256
+LG I +L R Q + K + PGP +FG+AL E S + + S
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGS--LDKVVSW-AHQ 76
Query: 257 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 436
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 437 HXXMIAPTFHINILKSFVGIFNQN 508
H ++ P FH ++LK +V +F ++
Sbjct: 137 HRKLLTPGFHYDVLKPYVAVFTES 160
>AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 62.5 bits (145), Expect = 1e-09
Identities = 42/144 (29%), Positives = 63/144 (43%)
Frame = +2
Query: 77 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCAT 256
+LG I +L R Q + K + PGP +FG+AL E S + + S
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGS--LDKVVSW-AHQ 76
Query: 257 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 436
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 437 HXXMIAPTFHINILKSFVGIFNQN 508
H ++ P FH ++LK +V +F ++
Sbjct: 137 HRKLLTPGFHYDVLKPYVAVFTES 160
>AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 62.5 bits (145), Expect = 1e-09
Identities = 42/144 (29%), Positives = 63/144 (43%)
Frame = +2
Query: 77 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCAT 256
+LG I +L R Q + K + PGP +FG+AL E S + + S
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGS--LDKVVSW-AHQ 76
Query: 257 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 436
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 437 HXXMIAPTFHINILKSFVGIFNQN 508
H ++ P FH ++LK +V +F ++
Sbjct: 137 HRKLLTPGFHYDVLKPYVAVFTES 160
>AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 62.5 bits (145), Expect = 1e-09
Identities = 42/144 (29%), Positives = 63/144 (43%)
Frame = +2
Query: 77 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCAT 256
+LG I +L R Q + K + PGP +FG+AL E S + + S
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGS--LDKVVSW-AHQ 76
Query: 257 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 436
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 437 HXXMIAPTFHINILKSFVGIFNQN 508
H ++ P FH ++LK +V +F ++
Sbjct: 137 HRKLLTPGFHYDVLKPYVAVFTES 160
>AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 62.5 bits (145), Expect = 1e-09
Identities = 42/144 (29%), Positives = 63/144 (43%)
Frame = +2
Query: 77 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCAT 256
+LG I +L R Q + K + PGP +FG+AL E S + + S
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGS--LDKVVSW-AHQ 76
Query: 257 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 436
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 437 HXXMIAPTFHINILKSFVGIFNQN 508
H ++ P FH ++LK +V +F ++
Sbjct: 137 HRKLLTPGFHYDVLKPYVAVFTES 160
>AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 62.5 bits (145), Expect = 1e-09
Identities = 42/144 (29%), Positives = 63/144 (43%)
Frame = +2
Query: 77 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCAT 256
+LG I +L R Q + K + PGP +FG+AL E S + + S
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGS--LDKVVSW-AHQ 76
Query: 257 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 436
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 437 HXXMIAPTFHINILKSFVGIFNQN 508
H ++ P FH ++LK +V +F ++
Sbjct: 137 HRKLLTPGFHYDVLKPYVAVFTES 160
>BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein.
Length = 357
Score = 61.7 bits (143), Expect = 2e-09
Identities = 46/156 (29%), Positives = 74/156 (47%), Gaps = 2/156 (1%)
Frame = +2
Query: 50 VNSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTX-HEEKSPRI 226
V S +I LL +++ +W + K + P P +FG+ H+++ RI
Sbjct: 21 VTSLLILLLLLIKAAQLYLHRQW-----LLKALQQFPCPPSHWLFGHIQEFQHDQELQRI 75
Query: 227 SQPRSGLCATFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEG 403
+ TF + W+ G K+ V L D D +++IL + YKF P +G G
Sbjct: 76 QER----VKTFPSACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPRIGYG 130
Query: 404 LLISSGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
LL+ +G W H M+ P FH +ILK +VG+ +V
Sbjct: 131 LLLLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSV 166
>J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung
cytochrome P450 (IV subfamily) BI protein, complete cds.
).
Length = 511
Score = 60.9 bits (141), Expect = 4e-09
Identities = 41/144 (28%), Positives = 63/144 (43%)
Frame = +2
Query: 77 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCAT 256
+LG I +L R + + K + PGP +FG+AL E S + + S
Sbjct: 23 VLGFLKLIHLLLRRRT---LAKAMDKFPGPPTHWLFGHALEIQETGS--LDKVVSW-AHQ 76
Query: 257 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 436
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 437 HXXMIAPTFHINILKSFVGIFNQN 508
H ++ P FH ++LK +V +F ++
Sbjct: 137 HRKLLTPGFHYDVLKPYVAVFTES 160
>AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 455
Score = 60.9 bits (141), Expect = 4e-09
Identities = 46/156 (29%), Positives = 74/156 (47%), Gaps = 2/156 (1%)
Frame = +2
Query: 50 VNSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTX-HEEKSPRI 226
V S +I LL +++ +W + K + P P +FG+ H+++ RI
Sbjct: 21 VTSLLILLLLLIKAAQLYLHRQW-----LLKALQQFPCPPSHWLFGHIQEFQHDQELQRI 75
Query: 227 SQPRSGLCATFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEG 403
+ TF + W+ G K+ V L D D +++IL + YKF P +G G
Sbjct: 76 QER----VKTFPSACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPRIGYG 130
Query: 404 LLISSGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
LL+ +G W H M+ P FH +ILK +VG+ +V
Sbjct: 131 LLLLNGQTWFQHRRMLTPAFHNDILKPYVGLMADSV 166
>AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 421
Score = 60.9 bits (141), Expect = 4e-09
Identities = 46/156 (29%), Positives = 74/156 (47%), Gaps = 2/156 (1%)
Frame = +2
Query: 50 VNSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTX-HEEKSPRI 226
V S +I LL +++ +W + K + P P +FG+ H+++ RI
Sbjct: 21 VTSLLILLLLLIKAAQLYLHRQW-----LLKALQQFPCPPSHWLFGHIQEFQHDQELQRI 75
Query: 227 SQPRSGLCATFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEG 403
+ TF + W+ G K+ V L D D +++IL + YKF P +G G
Sbjct: 76 QER----VKTFPSACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPRIGYG 130
Query: 404 LLISSGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
LL+ +G W H M+ P FH +ILK +VG+ +V
Sbjct: 131 LLLLNGQTWFQHRRMLTPAFHNDILKPYVGLMADSV 166
>AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 22 protein.
Length = 519
Score = 60.9 bits (141), Expect = 4e-09
Identities = 46/156 (29%), Positives = 74/156 (47%), Gaps = 2/156 (1%)
Frame = +2
Query: 50 VNSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTX-HEEKSPRI 226
V S +I LL +++ +W + K + P P +FG+ H+++ RI
Sbjct: 21 VTSLLILLLLLIKAAQLYLHRQW-----LLKALQQFPCPPSHWLFGHIQEFQHDQELQRI 75
Query: 227 SQPRSGLCATFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEG 403
+ TF + W+ G K+ V L D D +++IL + YKF P +G G
Sbjct: 76 QER----VKTFPSACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPRIGYG 130
Query: 404 LLISSGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
LL+ +G W H M+ P FH +ILK +VG+ +V
Sbjct: 131 LLLLNGQTWFQHRRMLTPAFHNDILKPYVGLMADSV 166
>AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid
omega-hydroxylase CYP4A11 protein.
Length = 519
Score = 59.7 bits (138), Expect = 9e-09
Identities = 45/156 (28%), Positives = 74/156 (47%), Gaps = 2/156 (1%)
Frame = +2
Query: 50 VNSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTX-HEEKSPRI 226
V S +I LL +++ +W + K + P P +FG+ H+++ RI
Sbjct: 21 VTSLLILLLLLIKAAQLYLHRQW-----LLKALQQFPCPPSHWLFGHIQEFQHDQELQRI 75
Query: 227 SQPRSGLCATFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEG 403
+ TF + W+ G K+ V L D D +++IL + Y+F P +G G
Sbjct: 76 QER----VKTFPSACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPRIGYG 130
Query: 404 LLISSGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
LL+ +G W H M+ P FH +ILK +VG+ +V
Sbjct: 131 LLLLNGQTWFQHRRMLTPAFHNDILKPYVGLMADSV 166
>AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein.
Length = 505
Score = 56.8 bits (131), Expect = 6e-08
Identities = 35/137 (25%), Positives = 62/137 (45%), Gaps = 1/137 (0%)
Frame = +2
Query: 104 ILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSP-RISQPRSGLCATFGNVVRVW 280
++ +Q+ M + L P P +G H+E P + + L + V +W
Sbjct: 29 VIRLYQRRRWMIRALHLFPAPPAHWFYG-----HKEFYPVKEFEVYHKLMEKYPCAVPLW 83
Query: 281 LGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHXXMIAPT 460
+G + F D IL A +K + W+G GL+ G KW+ H ++ P
Sbjct: 84 VGPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQIVKPG 143
Query: 461 FHINILKSFVGIFNQNV 511
F+I+ILK F+ + +++V
Sbjct: 144 FNISILKIFITMMSESV 160
>AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein.
Length = 505
Score = 56.8 bits (131), Expect = 6e-08
Identities = 35/137 (25%), Positives = 62/137 (45%), Gaps = 1/137 (0%)
Frame = +2
Query: 104 ILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSP-RISQPRSGLCATFGNVVRVW 280
++ +Q+ M + L P P +G H+E P + + L + V +W
Sbjct: 29 VIRLYQRRRWMIRALHLFPAPPAHWFYG-----HKEFYPVKEFEVYHKLMEKYPCAVPLW 83
Query: 281 LGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHXXMIAPT 460
+G + F D IL A +K + W+G GL+ G KW+ H ++ P
Sbjct: 84 VGPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQIVKPG 143
Query: 461 FHINILKSFVGIFNQNV 511
F+I+ILK F+ + +++V
Sbjct: 144 FNISILKIFITMMSESV 160
>AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 56.8 bits (131), Expect = 6e-08
Identities = 35/137 (25%), Positives = 62/137 (45%), Gaps = 1/137 (0%)
Frame = +2
Query: 104 ILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSP-RISQPRSGLCATFGNVVRVW 280
++ +Q+ M + L P P +G H+E P + + L + V +W
Sbjct: 29 VIRLYQRRRWMIRALHLFPAPPAHWFYG-----HKEFYPVKEFEVYHKLMEKYPCAVPLW 83
Query: 281 LGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHXXMIAPT 460
+G + F D IL A +K + W+G GL+ G KW+ H ++ P
Sbjct: 84 VGPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQIVKPG 143
Query: 461 FHINILKSFVGIFNQNV 511
F+I+ILK F+ + +++V
Sbjct: 144 FNISILKIFITMMSESV 160
>AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 56.8 bits (131), Expect = 6e-08
Identities = 35/137 (25%), Positives = 62/137 (45%), Gaps = 1/137 (0%)
Frame = +2
Query: 104 ILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSP-RISQPRSGLCATFGNVVRVW 280
++ +Q+ M + L P P +G H+E P + + L + V +W
Sbjct: 29 VIRLYQRRRWMIRALHLFPAPPAHWFYG-----HKEFYPVKEFEVYHKLMEKYPCAVPLW 83
Query: 281 LGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHXXMIAPT 460
+G + F D IL A +K + W+G GL+ G KW+ H ++ P
Sbjct: 84 VGPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQIVKPG 143
Query: 461 FHINILKSFVGIFNQNV 511
F+I+ILK F+ + +++V
Sbjct: 144 FNISILKIFITMMSESV 160
>AY696295-1|AAU10524.1| 292|Homo sapiens cytochrome P450 protein.
Length = 292
Score = 56.4 bits (130), Expect = 8e-08
Identities = 26/82 (31%), Positives = 48/82 (58%), Gaps = 1/82 (1%)
Frame = +2
Query: 269 VRVWLGSKLIVF-LADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHXX 445
V +W+G + F + D D ++I+L + A +K + W+G GL+ G KW+ H
Sbjct: 80 VPLWVGPFTMFFNIHDPDYVKILLKRQ-NPKSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138
Query: 446 MIAPTFHINILKSFVGIFNQNV 511
++ P F+I+ILK F+ + +++V
Sbjct: 139 IVKPGFNISILKIFITMMSKSV 160
>AK097373-1|BAC05026.1| 340|Homo sapiens protein ( Homo sapiens
cDNA FLJ40054 fis, clone TBAES2000315, weakly similar to
CYTOCHROME P450 4A1 (EC 1.14.15.3). ).
Length = 340
Score = 55.6 bits (128), Expect = 1e-07
Identities = 26/82 (31%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
Frame = +2
Query: 269 VRVWLGSKLIVF-LADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHXX 445
V +W+G + F + D D ++I+L A +K + W+G GL+ G KW+ H
Sbjct: 80 VPLWVGPFTMFFNIHDPDYVKILLKRQ-DPKSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138
Query: 446 MIAPTFHINILKSFVGIFNQNV 511
++ P F+I+ILK F+ + +++V
Sbjct: 139 IVKPGFNISILKIFITMMSKSV 160
>BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 55.2 bits (127), Expect = 2e-07
Identities = 43/154 (27%), Positives = 70/154 (45%), Gaps = 5/154 (3%)
Frame = +2
Query: 65 IFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIP--IFGNALTXHEEKSPRISQPR 238
+F LGL AI + R Q+ L +L P PAP G+ ++ ++ +
Sbjct: 19 VFCLALGLLQAIKLYLRRQR-----LLRDLRPFPAPPTHWFLGHQKFIQDDNMEKLEE-- 71
Query: 239 SGLCATFGNVVRVWLGSKLIVF-LADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLL 409
+ + W+G F + D D + +L+ D ++Y KF P LG+GL
Sbjct: 72 --IIEKYPRAFPFWIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLA 126
Query: 410 ISSGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
GPKW H ++ P FH NILK+++ + +V
Sbjct: 127 ALDGPKWFQHRRLLTPGFHFNILKAYIEVMAHSV 160
>AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein.
Length = 509
Score = 55.2 bits (127), Expect = 2e-07
Identities = 43/154 (27%), Positives = 70/154 (45%), Gaps = 5/154 (3%)
Frame = +2
Query: 65 IFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIP--IFGNALTXHEEKSPRISQPR 238
+F LGL AI + R Q+ L +L P PAP G+ ++ ++ +
Sbjct: 19 VFCLALGLLQAIKLYLRRQR-----LLRDLRPFPAPPTHWFLGHQKFIQDDNMEKLEE-- 71
Query: 239 SGLCATFGNVVRVWLGSKLIVF-LADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLL 409
+ + W+G F + D D + +L+ D ++Y KF P LG+GL
Sbjct: 72 --IIEKYPRAFPFWIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLA 126
Query: 410 ISSGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
GPKW H ++ P FH NILK+++ + +V
Sbjct: 127 ALDGPKWFQHRRLLTPGFHFNILKAYIEVMAHSV 160
>AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein.
Length = 509
Score = 55.2 bits (127), Expect = 2e-07
Identities = 43/154 (27%), Positives = 70/154 (45%), Gaps = 5/154 (3%)
Frame = +2
Query: 65 IFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIP--IFGNALTXHEEKSPRISQPR 238
+F LGL AI + R Q+ L +L P PAP G+ ++ ++ +
Sbjct: 19 VFCLALGLLQAIKLYLRRQR-----LLRDLRPFPAPPTHWFLGHQKFIQDDNMEKLEE-- 71
Query: 239 SGLCATFGNVVRVWLGSKLIVF-LADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLL 409
+ + W+G F + D D + +L+ D ++Y KF P LG+GL
Sbjct: 72 --IIEKYPRAFPFWIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLA 126
Query: 410 ISSGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
GPKW H ++ P FH NILK+++ + +V
Sbjct: 127 ALDGPKWFQHRRLLTPGFHFNILKAYIEVMAHSV 160
>AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 55.2 bits (127), Expect = 2e-07
Identities = 43/154 (27%), Positives = 70/154 (45%), Gaps = 5/154 (3%)
Frame = +2
Query: 65 IFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIP--IFGNALTXHEEKSPRISQPR 238
+F LGL AI + R Q+ L +L P PAP G+ ++ ++ +
Sbjct: 19 VFCLALGLLQAIKLYLRRQR-----LLRDLRPFPAPPTHWFLGHQKFIQDDNMEKLEE-- 71
Query: 239 SGLCATFGNVVRVWLGSKLIVF-LADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLL 409
+ + W+G F + D D + +L+ D ++Y KF P LG+GL
Sbjct: 72 --IIEKYPRAFPFWIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLA 126
Query: 410 ISSGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
GPKW H ++ P FH NILK+++ + +V
Sbjct: 127 ALDGPKWFQHRRLLTPGFHFNILKAYIEVMAHSV 160
>AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 509
Score = 55.2 bits (127), Expect = 2e-07
Identities = 43/154 (27%), Positives = 70/154 (45%), Gaps = 5/154 (3%)
Frame = +2
Query: 65 IFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIP--IFGNALTXHEEKSPRISQPR 238
+F LGL AI + R Q+ L +L P PAP G+ ++ ++ +
Sbjct: 19 VFCLALGLLQAIKLYLRRQR-----LLRDLRPFPAPPTHWFLGHQKFIQDDNMEKLEE-- 71
Query: 239 SGLCATFGNVVRVWLGSKLIVF-LADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLL 409
+ + W+G F + D D + +L+ D ++Y KF P LG+GL
Sbjct: 72 --IIEKYPRAFPFWIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLA 126
Query: 410 ISSGPKWRSHXXMIAPTFHINILKSFVGIFNQNV 511
GPKW H ++ P FH NILK+++ + +V
Sbjct: 127 ALDGPKWFQHRRLLTPGFHFNILKAYIEVMAHSV 160
>AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ16384 fis, clone TLIVE2007607, weakly similar
to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 508
Score = 52.4 bits (120), Expect = 1e-06
Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 3/81 (3%)
Frame = +2
Query: 278 WLGSKLIVF-LADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLLISSGPKWRSHXXM 448
W+G F + D D + +L+ D ++Y KF P LG+GL GPKW H +
Sbjct: 82 WIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 138
Query: 449 IAPTFHINILKSFVGIFNQNV 511
+ P FH NILK+++ + +V
Sbjct: 139 LTPGFHFNILKAYIEVMAHSV 159
>AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens
cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 444
Score = 52.4 bits (120), Expect = 1e-06
Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 3/81 (3%)
Frame = +2
Query: 278 WLGSKLIVF-LADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLLISSGPKWRSHXXM 448
W+G F + D D + +L+ D ++Y KF P LG+GL GPKW H +
Sbjct: 18 WIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 74
Query: 449 IAPTFHINILKSFVGIFNQNV 511
+ P FH NILK+++ + +V
Sbjct: 75 LTPGFHFNILKAYIEVMAHSV 95
>AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P450
4B1 variant protein.
Length = 497
Score = 47.2 bits (107), Expect = 5e-05
Identities = 16/38 (42%), Positives = 25/38 (65%)
Frame = +2
Query: 395 GEGLLISSGPKWRSHXXMIAPTFHINILKSFVGIFNQN 508
G GLL+ GPKW H ++ P FH ++LK +V +F ++
Sbjct: 108 GRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTES 145
>AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 47.2 bits (107), Expect = 5e-05
Identities = 16/38 (42%), Positives = 25/38 (65%)
Frame = +2
Query: 395 GEGLLISSGPKWRSHXXMIAPTFHINILKSFVGIFNQN 508
G GLL+ GPKW H ++ P FH ++LK +V +F ++
Sbjct: 108 GRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTES 145
>AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 47.2 bits (107), Expect = 5e-05
Identities = 16/38 (42%), Positives = 25/38 (65%)
Frame = +2
Query: 395 GEGLLISSGPKWRSHXXMIAPTFHINILKSFVGIFNQN 508
G GLL+ GPKW H ++ P FH ++LK +V +F ++
Sbjct: 108 GRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTES 145
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 44.0 bits (99), Expect = 5e-04
Identities = 36/144 (25%), Positives = 66/144 (45%), Gaps = 4/144 (2%)
Frame = +2
Query: 86 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATF 259
L ++ +LY + +SH KL +PGP P+P GN L+ H+ + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFCMFDMECHK----KY 68
Query: 260 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 433
G V + G + ++ + D D I+++L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKLVLVKECY-SVFTNREPFGPVGFMKSAISIAEDEEWK 127
Query: 434 SHXXMIAPTFHINILKSFVGIFNQ 505
+++PTF LK V I Q
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQ 151
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 44.0 bits (99), Expect = 5e-04
Identities = 36/144 (25%), Positives = 65/144 (45%), Gaps = 4/144 (2%)
Frame = +2
Query: 86 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATF 259
L ++ +LY + +SH KL +PGP P+P GN L+ H+ + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFCMFDMECHK----KY 68
Query: 260 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 433
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVCGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 434 SHXXMIAPTFHINILKSFVGIFNQ 505
+++PTF LK V I Q
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQ 151
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 44.0 bits (99), Expect = 5e-04
Identities = 36/144 (25%), Positives = 66/144 (45%), Gaps = 4/144 (2%)
Frame = +2
Query: 86 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATF 259
L ++ +LY + +SH KL +PGP P+P GN L+ H+ + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFCMFDMECHK----KY 68
Query: 260 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 433
G V + G + ++ + D D I+++L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKLVLVKECY-SVFTNREPFGPVGFMKSAISIAEDEEWK 127
Query: 434 SHXXMIAPTFHINILKSFVGIFNQ 505
+++PTF LK V I Q
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQ 151
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 43.6 bits (98), Expect = 6e-04
Identities = 36/144 (25%), Positives = 66/144 (45%), Gaps = 4/144 (2%)
Frame = +2
Query: 86 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATF 259
+ T++ +LY + +SH KL +PGP P+P GN L+ H+ + +
Sbjct: 15 VATSLVLLYIYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFCMFDMECHK----KY 68
Query: 260 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 433
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 434 SHXXMIAPTFHINILKSFVGIFNQ 505
+++PTF LK V I Q
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQ 151
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 43.2 bits (97), Expect = 8e-04
Identities = 36/144 (25%), Positives = 65/144 (45%), Gaps = 4/144 (2%)
Frame = +2
Query: 86 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATF 259
L ++ +LY + +SH KL +PGP P+P GN L+ H+ + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFCMFDMECHK----KY 68
Query: 260 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 433
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 434 SHXXMIAPTFHINILKSFVGIFNQ 505
+++PTF LK V I Q
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQ 151
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 43.2 bits (97), Expect = 8e-04
Identities = 36/144 (25%), Positives = 65/144 (45%), Gaps = 4/144 (2%)
Frame = +2
Query: 86 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATF 259
L ++ +LY + +SH KL +PGP P+P GN L+ H+ + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFCMFDMECHK----KY 68
Query: 260 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 433
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 434 SHXXMIAPTFHINILKSFVGIFNQ 505
+++PTF LK V I Q
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQ 151
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 43.2 bits (97), Expect = 8e-04
Identities = 36/144 (25%), Positives = 65/144 (45%), Gaps = 4/144 (2%)
Frame = +2
Query: 86 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATF 259
L ++ +LY + +SH KL +PGP P+P GN L+ H+ + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFCMFDMECHK----KY 68
Query: 260 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 433
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 434 SHXXMIAPTFHINILKSFVGIFNQ 505
+++PTF LK V I Q
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQ 151
>EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 321
Score = 43.2 bits (97), Expect = 8e-04
Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 2/115 (1%)
Frame = +2
Query: 149 ELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVVRVWLGSKLIVFLADADDI- 325
+L PGP P+PI GN L S + + L +G++ V LG + +V L+ +
Sbjct: 29 KLPPGPRPLPILGNLLLL---CSQDMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVK 85
Query: 326 EIILNSHVHIDKATEY-KFFKPWLGEGLLISSGPKWRSHXXMIAPTFHINILKSF 487
E +++ +Y FF G G+ SSG +W+ + F I IL++F
Sbjct: 86 EALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWK-----VLRQFSIQILRNF 135
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 43.2 bits (97), Expect = 8e-04
Identities = 36/144 (25%), Positives = 65/144 (45%), Gaps = 4/144 (2%)
Frame = +2
Query: 86 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATF 259
L ++ +LY + +SH KL +PGP P+P GN L+ H+ + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFCMFDMECHK----KY 68
Query: 260 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 433
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 434 SHXXMIAPTFHINILKSFVGIFNQ 505
+++PTF LK V I Q
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQ 151
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 43.2 bits (97), Expect = 8e-04
Identities = 36/144 (25%), Positives = 65/144 (45%), Gaps = 4/144 (2%)
Frame = +2
Query: 86 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATF 259
L ++ +LY + +SH KL +PGP P+P GN L+ H+ + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFCMFDMECHK----KY 68
Query: 260 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 433
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 434 SHXXMIAPTFHINILKSFVGIFNQ 505
+++PTF LK V I Q
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQ 151
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 43.2 bits (97), Expect = 8e-04
Identities = 36/144 (25%), Positives = 65/144 (45%), Gaps = 4/144 (2%)
Frame = +2
Query: 86 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATF 259
L ++ +LY + +SH KL +PGP P+P GN L+ H+ + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFCMFDMECHK----KY 68
Query: 260 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 433
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 434 SHXXMIAPTFHINILKSFVGIFNQ 505
+++PTF LK V I Q
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQ 151
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 43.2 bits (97), Expect = 8e-04
Identities = 36/144 (25%), Positives = 65/144 (45%), Gaps = 4/144 (2%)
Frame = +2
Query: 86 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATF 259
L ++ +LY + +SH KL +PGP P+P GN L+ H+ + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFCMFDMECHK----KY 68
Query: 260 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 433
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 434 SHXXMIAPTFHINILKSFVGIFNQ 505
+++PTF LK V I Q
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQ 151
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 43.2 bits (97), Expect = 8e-04
Identities = 36/144 (25%), Positives = 65/144 (45%), Gaps = 4/144 (2%)
Frame = +2
Query: 86 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATF 259
L ++ +LY + +SH KL +PGP P+P GN L+ H+ + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFCMFDMECHK----KY 68
Query: 260 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 433
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 434 SHXXMIAPTFHINILKSFVGIFNQ 505
+++PTF LK V I Q
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQ 151
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 43.2 bits (97), Expect = 8e-04
Identities = 36/144 (25%), Positives = 65/144 (45%), Gaps = 4/144 (2%)
Frame = +2
Query: 86 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATF 259
L ++ +LY + +SH KL +PGP P+P GN L+ H+ + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFCMFDMECHK----KY 68
Query: 260 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 433
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 434 SHXXMIAPTFHINILKSFVGIFNQ 505
+++PTF LK V I Q
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQ 151
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 43.2 bits (97), Expect = 8e-04
Identities = 36/144 (25%), Positives = 65/144 (45%), Gaps = 4/144 (2%)
Frame = +2
Query: 86 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATF 259
L ++ +LY + +SH KL +PGP P+P GN L+ H+ + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKGFCMFDMECHK----KY 68
Query: 260 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 433
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 434 SHXXMIAPTFHINILKSFVGIFNQ 505
+++PTF LK V I Q
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQ 151
>J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrome
P450IIE1 (ethanol-inducible) gene, complete cds. ).
Length = 493
Score = 41.5 bits (93), Expect = 0.003
Identities = 34/126 (26%), Positives = 57/126 (45%), Gaps = 8/126 (6%)
Frame = +2
Query: 80 LGLTTA--IWILY-----RWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPR 238
LG+T A +W + W+Q +H L PGP P+PI GN + P+ S R
Sbjct: 4 LGVTVALLVWAAFLLLVSMWRQ---VHSSWNLPPGPFPLPIIGNLFQLELKNIPK-SFTR 59
Query: 239 SGLCATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWLGEGLLIS 415
L FG V +++GS+ +V + + E +L+ + F G++ +
Sbjct: 60 --LAQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFN 117
Query: 416 SGPKWR 433
+GP W+
Sbjct: 118 NGPTWK 123
>J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrome
P-450j mRNA, complete cds. ).
Length = 493
Score = 41.5 bits (93), Expect = 0.003
Identities = 34/126 (26%), Positives = 57/126 (45%), Gaps = 8/126 (6%)
Frame = +2
Query: 80 LGLTTA--IWILY-----RWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPR 238
LG+T A +W + W+Q +H L PGP P+PI GN + P+ S R
Sbjct: 4 LGVTVALLVWAAFLLLVSMWRQ---VHSSWNLPPGPFPLPIIGNLFQLELKNIPK-SFTR 59
Query: 239 SGLCATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWLGEGLLIS 415
L FG V +++GS+ +V + + E +L+ + F G++ +
Sbjct: 60 --LAQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFN 117
Query: 416 SGPKWR 433
+GP W+
Sbjct: 118 NGPTWK 123
>DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 41.5 bits (93), Expect = 0.003
Identities = 34/126 (26%), Positives = 57/126 (45%), Gaps = 8/126 (6%)
Frame = +2
Query: 80 LGLTTA--IWILY-----RWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPR 238
LG+T A +W + W+Q +H L PGP P+PI GN + P+ S R
Sbjct: 4 LGVTVALLVWAAFLLLVSMWRQ---VHSSWNLPPGPFPLPIIGNLFQLELKNIPK-SFTR 59
Query: 239 SGLCATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWLGEGLLIS 415
L FG V +++GS+ +V + + E +L+ + F G++ +
Sbjct: 60 --LAQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFN 117
Query: 416 SGPKWR 433
+GP W+
Sbjct: 118 NGPTWK 123
>DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1
protein.
Length = 493
Score = 41.5 bits (93), Expect = 0.003
Identities = 34/126 (26%), Positives = 57/126 (45%), Gaps = 8/126 (6%)
Frame = +2
Query: 80 LGLTTA--IWILY-----RWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPR 238
LG+T A +W + W+Q +H L PGP P+PI GN + P+ S R
Sbjct: 4 LGVTVALLVWAAFLLLVSMWRQ---VHSSWNLPPGPFPLPIIGNLFQLELKNIPK-SFTR 59
Query: 239 SGLCATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWLGEGLLIS 415
L FG V +++GS+ +V + + E +L+ + F G++ +
Sbjct: 60 --LAQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFN 117
Query: 416 SGPKWR 433
+GP W+
Sbjct: 118 NGPTWK 123
>BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 41.5 bits (93), Expect = 0.003
Identities = 34/126 (26%), Positives = 57/126 (45%), Gaps = 8/126 (6%)
Frame = +2
Query: 80 LGLTTA--IWILY-----RWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPR 238
LG+T A +W + W+Q +H L PGP P+PI GN + P+ S R
Sbjct: 4 LGVTVALLVWAAFLLLVSMWRQ---VHSSWNLPPGPFPLPIIGNLFQLELKNIPK-SFTR 59
Query: 239 SGLCATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWLGEGLLIS 415
L FG V +++GS+ +V + + E +L+ + F G++ +
Sbjct: 60 --LAQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFN 117
Query: 416 SGPKWR 433
+GP W+
Sbjct: 118 NGPAWK 123
>AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 41.5 bits (93), Expect = 0.003
Identities = 34/126 (26%), Positives = 57/126 (45%), Gaps = 8/126 (6%)
Frame = +2
Query: 80 LGLTTA--IWILY-----RWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPR 238
LG+T A +W + W+Q +H L PGP P+PI GN + P+ S R
Sbjct: 4 LGVTVALLVWAAFLLLVSMWRQ---VHSSWNLPPGPFPLPIIGNLFQLELKNIPK-SFTR 59
Query: 239 SGLCATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWLGEGLLIS 415
L FG V +++GS+ +V + + E +L+ + F G++ +
Sbjct: 60 --LAQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFN 117
Query: 416 SGPKWR 433
+GP W+
Sbjct: 118 NGPTWK 123
>AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1
protein.
Length = 493
Score = 41.5 bits (93), Expect = 0.003
Identities = 34/126 (26%), Positives = 57/126 (45%), Gaps = 8/126 (6%)
Frame = +2
Query: 80 LGLTTA--IWILY-----RWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPR 238
LG+T A +W + W+Q +H L PGP P+PI GN + P+ S R
Sbjct: 4 LGVTVALLVWAAFLLLVSMWRQ---VHSSWNLPPGPFPLPIIGNLFQLELKNIPK-SFTR 59
Query: 239 SGLCATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWLGEGLLIS 415
L FG V +++GS+ +V + + E +L+ + F G++ +
Sbjct: 60 --LAQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFN 117
Query: 416 SGPKWR 433
+GP W+
Sbjct: 118 NGPTWK 123
>U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 40.7 bits (91), Expect = 0.004
Identities = 34/127 (26%), Positives = 54/127 (42%), Gaps = 3/127 (2%)
Frame = +2
Query: 56 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQP 235
S ++ LL T + ++ WQQ KL PGP P+P GN L + E I
Sbjct: 4 SGLLLVALLACLTVMVLMSVWQQRKSRGKLP---PGPTPLPFIGNYLQLNTE---HICDS 57
Query: 236 RSGLCATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 406
+G V + LG + +V L D + E +++ E F+ W+ G G+
Sbjct: 58 IMKFSECYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFE-WVFKGYGV 116
Query: 407 LISSGPK 427
S+G +
Sbjct: 117 AFSNGER 123
>U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 40.7 bits (91), Expect = 0.004
Identities = 33/127 (25%), Positives = 56/127 (44%), Gaps = 3/127 (2%)
Frame = +2
Query: 56 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQP 235
S ++ LL T + ++ WQQ KL PGP P+P GN L + E ++
Sbjct: 4 SGMLLVALLACLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQLNTE---QMYNS 57
Query: 236 RSGLCATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 406
+ +G V + LG + +V L D + E +++ E F W+ G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 407 LISSGPK 427
+ S+G +
Sbjct: 117 VFSNGER 123
>M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 39.9 bits (89), Expect = 0.008
Identities = 34/127 (26%), Positives = 53/127 (41%), Gaps = 3/127 (2%)
Frame = +2
Query: 56 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQP 235
S ++ LL T + ++ WQQ KL PGP P+P GN L + E I
Sbjct: 4 SGLLLVALLACLTVMVLMSVWQQRKSRGKLP---PGPTPLPFIGNYLQLNTE---HICDS 57
Query: 236 RSGLCATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 406
+G V + LG + +V L D + E +++ E F W+ G G+
Sbjct: 58 IMKFSECYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 407 LISSGPK 427
S+G +
Sbjct: 117 AFSNGER 123
>M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 39.9 bits (89), Expect = 0.008
Identities = 31/116 (26%), Positives = 55/116 (47%), Gaps = 2/116 (1%)
Frame = +2
Query: 92 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVV 271
+ + +L W+Q+S KL PGP P+P+ GN L + IS+ + L +G V
Sbjct: 7 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKD---ISKSLTNLSKVYGPVF 60
Query: 272 RVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWR 433
++ G K IV L + + E +++ + + G G++ S+G KW+
Sbjct: 61 TLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWK 116
>M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 39.9 bits (89), Expect = 0.008
Identities = 31/116 (26%), Positives = 55/116 (47%), Gaps = 2/116 (1%)
Frame = +2
Query: 92 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVV 271
+ + +L W+Q+S KL PGP P+P+ GN L + IS+ + L +G V
Sbjct: 7 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKD---ISKSLTNLSKVYGPVF 60
Query: 272 RVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWR 433
++ G K IV L + + E +++ + + G G++ S+G KW+
Sbjct: 61 TLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWK 116
>L16880-1|AAD13466.1| 273|Homo sapiens cytochrome P-450 2C protein.
Length = 273
Score = 39.9 bits (89), Expect = 0.008
Identities = 31/116 (26%), Positives = 55/116 (47%), Gaps = 2/116 (1%)
Frame = +2
Query: 92 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVV 271
+ + +L W+Q+S KL PGP P+P+ GN L + IS+ + L +G V
Sbjct: 12 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKD---ISKSLTNLSKVYGPVF 65
Query: 272 RVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWR 433
++ G K IV L + + E +++ + + G G++ S+G KW+
Sbjct: 66 TLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWK 121
>J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein.
Length = 491
Score = 39.9 bits (89), Expect = 0.008
Identities = 32/115 (27%), Positives = 53/115 (46%), Gaps = 2/115 (1%)
Frame = +2
Query: 149 ELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVVRVWLGSKLIVFLADADDI- 325
+L PGP P+ I GN L S + + L +G++ V LG + +V L+ +
Sbjct: 29 KLPPGPRPLSILGNLLLL---CSQDMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVK 85
Query: 326 EIILNSHVHIDKATEY-KFFKPWLGEGLLISSGPKWRSHXXMIAPTFHINILKSF 487
E +++ +Y FF G G+ SSG +W+ + F I IL++F
Sbjct: 86 EALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWK-----VLRQFSIQILRNF 135
>EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 491
Score = 39.9 bits (89), Expect = 0.008
Identities = 32/115 (27%), Positives = 53/115 (46%), Gaps = 2/115 (1%)
Frame = +2
Query: 149 ELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVVRVWLGSKLIVFLADADDI- 325
+L PGP P+ I GN L S + + L +G++ V LG + +V L+ +
Sbjct: 29 KLPPGPRPLSILGNLLLL---CSQDMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVK 85
Query: 326 EIILNSHVHIDKATEY-KFFKPWLGEGLLISSGPKWRSHXXMIAPTFHINILKSF 487
E +++ +Y FF G G+ SSG +W+ + F I IL++F
Sbjct: 86 EALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWK-----VLRQFSIQILRNF 135
>D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein.
Length = 487
Score = 39.9 bits (89), Expect = 0.008
Identities = 31/116 (26%), Positives = 55/116 (47%), Gaps = 2/116 (1%)
Frame = +2
Query: 92 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVV 271
+ + +L W+Q+S KL PGP P+P+ GN L + IS+ + L +G V
Sbjct: 9 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKD---ISKSLTNLSKVYGPVF 62
Query: 272 RVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWR 433
++ G K IV L + + E +++ + + G G++ S+G KW+
Sbjct: 63 TLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWK 118
>BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 39.9 bits (89), Expect = 0.008
Identities = 31/116 (26%), Positives = 55/116 (47%), Gaps = 2/116 (1%)
Frame = +2
Query: 92 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVV 271
+ + +L W+Q+S KL PGP P+P+ GN L + IS+ + L +G V
Sbjct: 12 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKD---ISKSLTNLSKVYGPVF 65
Query: 272 RVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWR 433
++ G K IV L + + E +++ + + G G++ S+G KW+
Sbjct: 66 TLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWK 121
>BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein.
Length = 320
Score = 39.9 bits (89), Expect = 0.008
Identities = 32/115 (27%), Positives = 53/115 (46%), Gaps = 2/115 (1%)
Frame = +2
Query: 149 ELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVVRVWLGSKLIVFLADADDI- 325
+L PGP P+ I GN L S + + L +G++ V LG + +V L+ +
Sbjct: 29 KLPPGPRPLSILGNLLLL---CSQDMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVK 85
Query: 326 EIILNSHVHIDKATEY-KFFKPWLGEGLLISSGPKWRSHXXMIAPTFHINILKSF 487
E +++ +Y FF G G+ SSG +W+ + F I IL++F
Sbjct: 86 EALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWK-----VLRQFSIQILRNF 135
>BC070317-1|AAH70317.1| 162|Homo sapiens CYP2C9 protein protein.
Length = 162
Score = 39.9 bits (89), Expect = 0.008
Identities = 31/116 (26%), Positives = 55/116 (47%), Gaps = 2/116 (1%)
Frame = +2
Query: 92 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVV 271
+ + +L W+Q+S KL PGP P+P+ GN L + IS+ + L +G V
Sbjct: 12 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKD---ISKSLTNLSKVYGPVF 65
Query: 272 RVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWR 433
++ G K IV L + + E +++ + + G G++ S+G KW+
Sbjct: 66 TLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWK 121
>BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 39.9 bits (89), Expect = 0.008
Identities = 34/126 (26%), Positives = 56/126 (44%), Gaps = 8/126 (6%)
Frame = +2
Query: 80 LGLTTA--IWILY-----RWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPR 238
LG+T A +W + W+Q +H L PGP P+PI GN + P+ S R
Sbjct: 4 LGVTVALLVWAAFLLLVSMWRQ---VHSSWNLPPGPFPLPIIGNLFQLELKNIPK-SFTR 59
Query: 239 SGLCATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWLGEGLLIS 415
L FG V + +GS+ +V + + E +L+ + F G++ +
Sbjct: 60 --LAQRFGPVFTLCVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFN 117
Query: 416 SGPKWR 433
+GP W+
Sbjct: 118 NGPTWK 123
>BC020754-1|AAH20754.1| 162|Homo sapiens CYP2C9 protein protein.
Length = 162
Score = 39.9 bits (89), Expect = 0.008
Identities = 31/116 (26%), Positives = 55/116 (47%), Gaps = 2/116 (1%)
Frame = +2
Query: 92 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVV 271
+ + +L W+Q+S KL PGP P+P+ GN L + IS+ + L +G V
Sbjct: 12 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKD---ISKSLTNLSKVYGPVF 65
Query: 272 RVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWR 433
++ G K IV L + + E +++ + + G G++ S+G KW+
Sbjct: 66 TLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWK 121
>AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 39.9 bits (89), Expect = 0.008
Identities = 31/116 (26%), Positives = 55/116 (47%), Gaps = 2/116 (1%)
Frame = +2
Query: 92 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVV 271
+ + +L W+Q+S KL PGP P+P+ GN L + IS+ + L +G V
Sbjct: 12 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKD---ISKSLTNLSKVYGPVF 65
Query: 272 RVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWR 433
++ G K IV L + + E +++ + + G G++ S+G KW+
Sbjct: 66 TLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWK 121
>AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 39.9 bits (89), Expect = 0.008
Identities = 31/116 (26%), Positives = 55/116 (47%), Gaps = 2/116 (1%)
Frame = +2
Query: 92 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVV 271
+ + +L W+Q+S KL PGP P+P+ GN L + IS+ + L +G V
Sbjct: 12 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKD---ISKSLTNLSKVYGPVF 65
Query: 272 RVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWR 433
++ G K IV L + + E +++ + + G G++ S+G KW+
Sbjct: 66 TLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWK 121
>AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 39.9 bits (89), Expect = 0.008
Identities = 31/116 (26%), Positives = 55/116 (47%), Gaps = 2/116 (1%)
Frame = +2
Query: 92 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVV 271
+ + +L W+Q+S KL PGP P+P+ GN L + IS+ + L +G V
Sbjct: 12 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKD---ISKSLTNLSKVYGPVF 65
Query: 272 RVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWR 433
++ G K IV L + + E +++ + + G G++ S+G KW+
Sbjct: 66 TLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWK 121
>AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1
protein.
Length = 495
Score = 39.9 bits (89), Expect = 0.008
Identities = 32/115 (27%), Positives = 53/115 (46%), Gaps = 2/115 (1%)
Frame = +2
Query: 149 ELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVVRVWLGSKLIVFLADADDI- 325
+L PGP P+ I GN L S + + L +G++ V LG + +V L+ +
Sbjct: 29 KLPPGPRPLSILGNLLLL---CSQDMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVK 85
Query: 326 EIILNSHVHIDKATEY-KFFKPWLGEGLLISSGPKWRSHXXMIAPTFHINILKSF 487
E +++ +Y FF G G+ SSG +W+ + F I IL++F
Sbjct: 86 EALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWK-----VLRQFSIQILRNF 135
>X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mRNA
for P-450 IIA4 protein. ).
Length = 494
Score = 39.5 bits (88), Expect = 0.010
Identities = 33/127 (25%), Positives = 56/127 (44%), Gaps = 3/127 (2%)
Frame = +2
Query: 56 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQP 235
S ++ LL T + ++ WQQ KL PGP P+P GN L + E ++
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQLNTE---QMYNS 57
Query: 236 RSGLCATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 406
+ +G V + LG + +V L D + E +++ E F W+ G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 407 LISSGPK 427
+ S+G +
Sbjct: 117 VFSNGER 123
>X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for
cytochrome P-450IIA. ).
Length = 489
Score = 39.5 bits (88), Expect = 0.010
Identities = 32/125 (25%), Positives = 56/125 (44%), Gaps = 3/125 (2%)
Frame = +2
Query: 62 VIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRS 241
++ LL T + ++ WQQ + KL PGP P+P GN L + E ++
Sbjct: 1 MLLVALLVCLTVMVLMSVWQQRKNKGKLP---PGPTPLPFIGNYLQLNTE---QMYNSLM 54
Query: 242 GLCATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGLLI 412
+ +G V + LG + +V L D + E +++ E F W+ G G++
Sbjct: 55 KISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGVVF 113
Query: 413 SSGPK 427
S+G +
Sbjct: 114 SNGER 118
>U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 39.5 bits (88), Expect = 0.010
Identities = 33/127 (25%), Positives = 55/127 (43%), Gaps = 3/127 (2%)
Frame = +2
Query: 56 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQP 235
S ++ LL T + ++ W+Q KL PGP P+P GN L + E ++
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLP---PGPTPLPFIGNYLQLNTE---QMYNS 57
Query: 236 RSGLCATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 406
+ +G V + LG + +V L D + E +++ E F WL G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATF-DWLFKGYGV 116
Query: 407 LISSGPK 427
S+G +
Sbjct: 117 AFSNGER 123
>S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein.
Length = 477
Score = 39.5 bits (88), Expect = 0.010
Identities = 31/112 (27%), Positives = 53/112 (47%), Gaps = 2/112 (1%)
Frame = +2
Query: 104 ILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVVRVWL 283
+L W+Q+S KL PGP P+P+ GN L + IS+ + L +G V ++
Sbjct: 3 LLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKD---ISKSLTNLSKVYGPVFTLYF 56
Query: 284 GSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWR 433
G K IV L + + E +++ + + G G++ S+G KW+
Sbjct: 57 GLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWK 108
>M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 39.5 bits (88), Expect = 0.010
Identities = 33/127 (25%), Positives = 56/127 (44%), Gaps = 3/127 (2%)
Frame = +2
Query: 56 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQP 235
S ++ LL T + ++ WQQ KL PGP P+P GN L + E ++
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQLNTE---QMYNS 57
Query: 236 RSGLCATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 406
+ +G V + LG + +V L D + E +++ E F W+ G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 407 LISSGPK 427
+ S+G +
Sbjct: 117 VFSNGER 123
>BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 39.5 bits (88), Expect = 0.010
Identities = 33/127 (25%), Positives = 56/127 (44%), Gaps = 3/127 (2%)
Frame = +2
Query: 56 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQP 235
S ++ LL T + ++ WQQ KL PGP P+P GN L + E ++
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQLNTE---QMYNS 57
Query: 236 RSGLCATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 406
+ +G V + LG + +V L D + E +++ E F W+ G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 407 LISSGPK 427
+ S+G +
Sbjct: 117 VFSNGER 123
>BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 39.5 bits (88), Expect = 0.010
Identities = 33/127 (25%), Positives = 56/127 (44%), Gaps = 3/127 (2%)
Frame = +2
Query: 56 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQP 235
S ++ LL T + ++ WQQ KL PGP P+P GN L + E ++
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQLNTE---QMYNS 57
Query: 236 RSGLCATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 406
+ +G V + LG + +V L D + E +++ E F W+ G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 407 LISSGPK 427
+ S+G +
Sbjct: 117 VFSNGER 123
>BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 39.5 bits (88), Expect = 0.010
Identities = 33/127 (25%), Positives = 56/127 (44%), Gaps = 3/127 (2%)
Frame = +2
Query: 56 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQP 235
S ++ LL T + ++ WQQ KL PGP P+P GN L + E ++
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQLNTE---QMYNS 57
Query: 236 RSGLCATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 406
+ +G V + LG + +V L D + E +++ E F W+ G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 407 LISSGPK 427
+ S+G +
Sbjct: 117 VFSNGER 123
>BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 39.5 bits (88), Expect = 0.010
Identities = 33/127 (25%), Positives = 56/127 (44%), Gaps = 3/127 (2%)
Frame = +2
Query: 56 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQP 235
S ++ LL T + ++ WQQ KL PGP P+P GN L + E ++
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQLNTE---QMYNS 57
Query: 236 RSGLCATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 406
+ +G V + LG + +V L D + E +++ E F W+ G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 407 LISSGPK 427
+ S+G +
Sbjct: 117 VFSNGER 123
>AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13
variant 6 protein.
Length = 494
Score = 39.5 bits (88), Expect = 0.010
Identities = 33/127 (25%), Positives = 55/127 (43%), Gaps = 3/127 (2%)
Frame = +2
Query: 56 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQP 235
S ++ LL T + ++ W+Q KL PGP P+P GN L + E ++
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLP---PGPTPLPFIGNYLQLNTE---QMYNS 57
Query: 236 RSGLCATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 406
+ +G V + LG + +V L D + E +++ E F WL G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATF-DWLFKGYGV 116
Query: 407 LISSGPK 427
S+G +
Sbjct: 117 AFSNGER 123
>AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13
variant 5 protein.
Length = 494
Score = 39.5 bits (88), Expect = 0.010
Identities = 33/127 (25%), Positives = 55/127 (43%), Gaps = 3/127 (2%)
Frame = +2
Query: 56 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQP 235
S ++ LL T + ++ W+Q KL PGP P+P GN L + E ++
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLP---PGPTPLPFIGNYLQLNTE---QMYNS 57
Query: 236 RSGLCATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 406
+ +G V + LG + +V L D + E +++ E F WL G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATF-DWLFKGYGV 116
Query: 407 LISSGPK 427
S+G +
Sbjct: 117 AFSNGER 123
>AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13
variant 3 protein.
Length = 494
Score = 39.5 bits (88), Expect = 0.010
Identities = 33/127 (25%), Positives = 55/127 (43%), Gaps = 3/127 (2%)
Frame = +2
Query: 56 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQP 235
S ++ LL T + ++ W+Q KL PGP P+P GN L + E ++
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLP---PGPTPLPFIGNYLQLNTE---QMYNS 57
Query: 236 RSGLCATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 406
+ +G V + LG + +V L D + E +++ E F WL G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATF-DWLFKGYGV 116
Query: 407 LISSGPK 427
S+G +
Sbjct: 117 AFSNGER 123
>AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13
variant 2 protein.
Length = 494
Score = 39.5 bits (88), Expect = 0.010
Identities = 33/127 (25%), Positives = 55/127 (43%), Gaps = 3/127 (2%)
Frame = +2
Query: 56 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQP 235
S ++ LL T + ++ W+Q KL PGP P+P GN L + E ++
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLP---PGPTPLPFIGNYLQLNTE---QMYNS 57
Query: 236 RSGLCATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 406
+ +G V + LG + +V L D + E +++ E F WL G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATF-DWLFKGYGV 116
Query: 407 LISSGPK 427
S+G +
Sbjct: 117 AFSNGER 123
>AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13
variant 1 protein.
Length = 494
Score = 39.5 bits (88), Expect = 0.010
Identities = 33/127 (25%), Positives = 55/127 (43%), Gaps = 3/127 (2%)
Frame = +2
Query: 56 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQP 235
S ++ LL T + ++ W+Q KL PGP P+P GN L + E ++
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLP---PGPTPLPFIGNYLQLNTE---QMYNS 57
Query: 236 RSGLCATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 406
+ +G V + LG + +V L D + E +++ E F WL G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATF-DWLFKGYGV 116
Query: 407 LISSGPK 427
S+G +
Sbjct: 117 AFSNGER 123
>AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13
protein.
Length = 494
Score = 39.5 bits (88), Expect = 0.010
Identities = 33/127 (25%), Positives = 55/127 (43%), Gaps = 3/127 (2%)
Frame = +2
Query: 56 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQP 235
S ++ LL T + ++ W+Q KL PGP P+P GN L + E ++
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLP---PGPTPLPFIGNYLQLNTE---QMYNS 57
Query: 236 RSGLCATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 406
+ +G V + LG + +V L D + E +++ E F WL G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATF-DWLFKGYGV 116
Query: 407 LISSGPK 427
S+G +
Sbjct: 117 AFSNGER 123
>AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6
protein.
Length = 494
Score = 39.5 bits (88), Expect = 0.010
Identities = 33/127 (25%), Positives = 56/127 (44%), Gaps = 3/127 (2%)
Frame = +2
Query: 56 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQP 235
S ++ LL T + ++ WQQ KL PGP P+P GN L + E ++
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQLNTE---QMYNS 57
Query: 236 RSGLCATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 406
+ +G V + LG + +V L D + E +++ E F W+ G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 407 LISSGPK 427
+ S+G +
Sbjct: 117 VFSNGER 123
>S63426-1|ABB76283.1| 214|Homo sapiens (S)-mephenytoin hydroxylase
associated cytochrome P450 protein.
Length = 214
Score = 39.1 bits (87), Expect = 0.014
Identities = 31/116 (26%), Positives = 54/116 (46%), Gaps = 2/116 (1%)
Frame = +2
Query: 92 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVV 271
+ +++L W+Q+S +L GP P+PI GN L + +S+ + +G V
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVKD---MSKSLTNFSKVYGPVF 65
Query: 272 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWR 433
V+ G K IV L + ++ L H + + K G G+L S+G +W+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWK 121
>M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 39.1 bits (87), Expect = 0.014
Identities = 31/116 (26%), Positives = 54/116 (46%), Gaps = 2/116 (1%)
Frame = +2
Query: 92 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVV 271
+ +++L W+Q+S +L GP P+PI GN L + +S+ + +G V
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVKD---MSKSLTNFSKVYGPVF 65
Query: 272 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWR 433
V+ G K IV L + ++ L H + + K G G+L S+G +W+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWK 121
>L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18
protein.
Length = 490
Score = 39.1 bits (87), Expect = 0.014
Identities = 31/116 (26%), Positives = 54/116 (46%), Gaps = 2/116 (1%)
Frame = +2
Query: 92 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVV 271
+ +++L W+Q+S +L GP P+PI GN L + +S+ + +G V
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVKD---MSKSLTNFSKVYGPVF 65
Query: 272 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWR 433
V+ G K IV L + ++ L H + + K G G+L S+G +W+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWK 121
>BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein.
Length = 431
Score = 39.1 bits (87), Expect = 0.014
Identities = 31/116 (26%), Positives = 54/116 (46%), Gaps = 2/116 (1%)
Frame = +2
Query: 92 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVV 271
+ +++L W+Q+S +L GP P+PI GN L + +S+ + +G V
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVKD---MSKSLTNFSKVYGPVF 65
Query: 272 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWR 433
V+ G K IV L + ++ L H + + K G G+L S+G +W+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWK 121
>BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein.
Length = 443
Score = 39.1 bits (87), Expect = 0.014
Identities = 31/116 (26%), Positives = 54/116 (46%), Gaps = 2/116 (1%)
Frame = +2
Query: 92 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVV 271
+ +++L W+Q+S +L GP P+PI GN L + +S+ + +G V
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVKD---MSKSLTNFSKVYGPVF 65
Query: 272 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWR 433
V+ G K IV L + ++ L H + + K G G+L S+G +W+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWK 121
>BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 39.1 bits (87), Expect = 0.014
Identities = 31/116 (26%), Positives = 54/116 (46%), Gaps = 2/116 (1%)
Frame = +2
Query: 92 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVV 271
+ +++L W+Q+S +L GP P+PI GN L + +S+ + +G V
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVKD---MSKSLTNFSKVYGPVF 65
Query: 272 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWR 433
V+ G K IV L + ++ L H + + K G G+L S+G +W+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWK 121
>BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 39.1 bits (87), Expect = 0.014
Identities = 31/116 (26%), Positives = 54/116 (46%), Gaps = 2/116 (1%)
Frame = +2
Query: 92 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVV 271
+ +++L W+Q+S +L GP P+PI GN L + +S+ + +G V
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVKD---MSKSLTNFSKVYGPVF 65
Query: 272 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWR 433
V+ G K IV L + ++ L H + + K G G+L S+G +W+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWK 121
>BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 39.1 bits (87), Expect = 0.014
Identities = 31/116 (26%), Positives = 54/116 (46%), Gaps = 2/116 (1%)
Frame = +2
Query: 92 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVV 271
+ +++L W+Q+S +L GP P+PI GN L + +S+ + +G V
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVKD---MSKSLTNFSKVYGPVF 65
Query: 272 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWR 433
V+ G K IV L + ++ L H + + K G G+L S+G +W+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWK 121
>AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 39.1 bits (87), Expect = 0.014
Identities = 31/116 (26%), Positives = 54/116 (46%), Gaps = 2/116 (1%)
Frame = +2
Query: 92 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVV 271
+ +++L W+Q+S +L GP P+PI GN L + +S+ + +G V
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVKD---MSKSLTNFSKVYGPVF 65
Query: 272 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWR 433
V+ G K IV L + ++ L H + + K G G+L S+G +W+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWK 121
>AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 variant protein.
Length = 490
Score = 38.7 bits (86), Expect = 0.018
Identities = 31/116 (26%), Positives = 53/116 (45%), Gaps = 2/116 (1%)
Frame = +2
Query: 92 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVV 271
+ +++L W Q+S +L GP P+PI GN L + +S+ + +G V
Sbjct: 12 SCLFLLSLWGQSSGRGRLPS---GPTPLPIIGNILQLDVKD---MSKSLTNFSKVYGPVF 65
Query: 272 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWR 433
V+ G K IV L + ++ L H + + K G G+L S+G +W+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFFGRGSFPVAEKVNKGLGILFSNGKRWK 121
>BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 7 protein.
Length = 494
Score = 38.3 bits (85), Expect = 0.024
Identities = 34/127 (26%), Positives = 52/127 (40%), Gaps = 3/127 (2%)
Frame = +2
Query: 56 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQP 235
S ++ LL T + ++ WQQ KL PGP P+P GN L + E I
Sbjct: 4 SGLLLVALLACLTVMVLMSVWQQRKSRGKLP---PGPTPLPFIGNYLQLNTE---HICDS 57
Query: 236 RSGLCATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 406
+G V + LG + V L D + E +++ E F W+ G G+
Sbjct: 58 IMKFSECYGPVFTIHLGPRRAVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 407 LISSGPK 427
S+G +
Sbjct: 117 AFSNGER 123
>AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1
protein.
Length = 462
Score = 38.3 bits (85), Expect = 0.024
Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Frame = +2
Query: 152 LLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVVRVWLGSKLIVFLADADDI-E 328
L PGP P+PI GN + P+ S R L FG V +++GS+ +V + + E
Sbjct: 1 LPPGPFPLPIIGNLFQLELKNIPK-SFTR--LAQRFGPVFTLYVGSQRMVVMHGYKAVKE 57
Query: 329 IILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWR 433
+L+ + F G++ ++GP W+
Sbjct: 58 ALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWK 92
>AY513607-1|AAR90938.1| 100|Homo sapiens truncated cytochrome P450
2A13 variant 4 protein.
Length = 100
Score = 37.9 bits (84), Expect = 0.032
Identities = 28/106 (26%), Positives = 48/106 (45%)
Frame = +2
Query: 56 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQP 235
S ++ LL T + ++ W+Q KL PGP P+P GN L + E ++
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLP---PGPTPLPFIGNYLQLNTE---QMYNS 57
Query: 236 RSGLCATFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEY 373
+ +G V + LG + +V L D ++ L +D+A E+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVKEAL-----VDQAEEF 98
>M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 37.1 bits (82), Expect = 0.055
Identities = 29/124 (23%), Positives = 58/124 (46%), Gaps = 2/124 (1%)
Frame = +2
Query: 68 FYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGL 247
F L+ + + +L W+Q+S KL PGP P+P+ GN L + +S+ + L
Sbjct: 4 FVVLVLCLSCLLLLSIWRQSSGRGKLP---PGPTPLPVIGNILQIDIKD---VSKSLTNL 57
Query: 248 CATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSG 421
+G V ++ G + +V L + + E +++ + + G G++ S+G
Sbjct: 58 SKIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSNG 117
Query: 422 PKWR 433
+W+
Sbjct: 118 KRWK 121
>M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein.
Length = 377
Score = 37.1 bits (82), Expect = 0.055
Identities = 30/118 (25%), Positives = 53/118 (44%), Gaps = 2/118 (1%)
Frame = +2
Query: 86 LTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGN 265
LT + +L + NSH L PGP P+P+ GN L + + +G+
Sbjct: 12 LTGLLLLLVQRHPNSH----GTLPPGPRPLPLLGNLLQMDRR---GLLKSFLRFREKYGD 64
Query: 266 VVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKP-WLGEGLLISSGPKWR 433
V V LG + +V L + I E ++++ + P + G G+L ++G +W+
Sbjct: 65 VFTVHLGPRPVVMLCGVEAIREALVDNAEAFSGRGKIVIMDPVYQGYGMLFANGNRWK 122
>L39098-1|AAL31347.1| 160|Homo sapiens S-mephenytoin 4-hydroxylase
protein.
Length = 160
Score = 37.1 bits (82), Expect = 0.055
Identities = 29/124 (23%), Positives = 58/124 (46%), Gaps = 2/124 (1%)
Frame = +2
Query: 68 FYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGL 247
F L+ + + +L W+Q+S KL PGP P+P+ GN L + +S+ + L
Sbjct: 4 FVVLVLCLSCLLLLSIWRQSSGRGKLP---PGPTPLPVIGNILQIDIKD---VSKSLTNL 57
Query: 248 CATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSG 421
+G V ++ G + +V L + + E +++ + + G G++ S+G
Sbjct: 58 SKIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSNG 117
Query: 422 PKWR 433
+W+
Sbjct: 118 KRWK 121
>BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein.
Length = 377
Score = 37.1 bits (82), Expect = 0.055
Identities = 30/118 (25%), Positives = 53/118 (44%), Gaps = 2/118 (1%)
Frame = +2
Query: 86 LTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGN 265
LT + +L + NSH L PGP P+P+ GN L + + +G+
Sbjct: 12 LTGLLLLLVQRHPNSH----GTLPPGPRPLPLLGNLLQMDRR---GLLKSFLRFREKYGD 64
Query: 266 VVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKP-WLGEGLLISSGPKWR 433
V V LG + +V L + I E ++++ + P + G G+L ++G +W+
Sbjct: 65 VFTVHLGPRPVVMLCGVEAIREALVDNAEAFSGRGKIVIMDPVYQGYGMLFANGNRWK 122
>AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 37.1 bits (82), Expect = 0.055
Identities = 29/124 (23%), Positives = 58/124 (46%), Gaps = 2/124 (1%)
Frame = +2
Query: 68 FYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGL 247
F L+ + + +L W+Q+S KL PGP P+P+ GN L + +S+ + L
Sbjct: 4 FVVLVLCLSCLLLLSIWRQSSGRGKLP---PGPTPLPVIGNILQIDIKD---VSKSLTNL 57
Query: 248 CATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSG 421
+G V ++ G + +V L + + E +++ + + G G++ S+G
Sbjct: 58 SKIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSNG 117
Query: 422 PKWR 433
+W+
Sbjct: 118 KRWK 121
>AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 37.1 bits (82), Expect = 0.055
Identities = 29/124 (23%), Positives = 58/124 (46%), Gaps = 2/124 (1%)
Frame = +2
Query: 68 FYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGL 247
F L+ + + +L W+Q+S KL PGP P+P+ GN L + +S+ + L
Sbjct: 4 FVVLVLCLSCLLLLSIWRQSSGRGKLP---PGPTPLPVIGNILQIDIKD---VSKSLTNL 57
Query: 248 CATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSG 421
+G V ++ G + +V L + + E +++ + + G G++ S+G
Sbjct: 58 SKIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSNG 117
Query: 422 PKWR 433
+W+
Sbjct: 118 KRWK 121
>AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 37.1 bits (82), Expect = 0.055
Identities = 29/124 (23%), Positives = 58/124 (46%), Gaps = 2/124 (1%)
Frame = +2
Query: 68 FYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGL 247
F L+ + + +L W+Q+S KL PGP P+P+ GN L + +S+ + L
Sbjct: 4 FVVLVLCLSCLLLLSIWRQSSGRGKLP---PGPTPLPVIGNILQIDIKD---VSKSLTNL 57
Query: 248 CATFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSG 421
+G V ++ G + +V L + + E +++ + + G G++ S+G
Sbjct: 58 SKIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSNG 117
Query: 422 PKWR 433
+W+
Sbjct: 118 KRWK 121
>BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 36.7 bits (81), Expect = 0.073
Identities = 30/124 (24%), Positives = 54/124 (43%), Gaps = 3/124 (2%)
Frame = +2
Query: 71 YPLLGLTTAIWILYR-WQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGL 247
+ +L L + +L+ W+Q+ KL PGP P+PI GN L + I + +
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNMLQIDVKD---ICKSFTNF 57
Query: 248 CATFGNVVRVWLGSKLIVFLADADDIE--IILNSHVHIDKATEYKFFKPWLGEGLLISSG 421
+G V V+ G IV + ++ +I N + + G G++ S+G
Sbjct: 58 SKVYGPVFTVYFGMNPIVVFHGYESVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNG 117
Query: 422 PKWR 433
+W+
Sbjct: 118 KRWK 121
>Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein.
Length = 490
Score = 35.9 bits (79), Expect = 0.13
Identities = 30/124 (24%), Positives = 54/124 (43%), Gaps = 3/124 (2%)
Frame = +2
Query: 71 YPLLGLTTAIWILYR-WQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGL 247
+ +L L + +L+ W+Q+ KL PGP P+PI GN L + I + +
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNMLQIDVKD---ICKSFTNF 57
Query: 248 CATFGNVVRVWLGSKLIVFLADADDIE--IILNSHVHIDKATEYKFFKPWLGEGLLISSG 421
+G V V+ G IV + ++ +I N + + G G++ S+G
Sbjct: 58 SKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNG 117
Query: 422 PKWR 433
+W+
Sbjct: 118 KRWK 121
>M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrome
P-450 1 mRNA, complete cds, clone Hp1-2. ).
Length = 393
Score = 35.9 bits (79), Expect = 0.13
Identities = 30/124 (24%), Positives = 54/124 (43%), Gaps = 3/124 (2%)
Frame = +2
Query: 71 YPLLGLTTAIWILYR-WQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGL 247
+ +L L + +L+ W+Q+ KL PGP P+PI GN L + I + +
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNMLQIDVKD---ICKSFTNF 57
Query: 248 CATFGNVVRVWLGSKLIVFLADADDIE--IILNSHVHIDKATEYKFFKPWLGEGLLISSG 421
+G V V+ G IV + ++ +I N + + G G++ S+G
Sbjct: 58 SKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNG 117
Query: 422 PKWR 433
+W+
Sbjct: 118 KRWK 121
>M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrome
P-450 1 functional form mRNA, complete cds. ).
Length = 490
Score = 35.9 bits (79), Expect = 0.13
Identities = 30/124 (24%), Positives = 54/124 (43%), Gaps = 3/124 (2%)
Frame = +2
Query: 71 YPLLGLTTAIWILYR-WQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGL 247
+ +L L + +L+ W+Q+ KL PGP P+PI GN L + I + +
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNMLQIDVKD---ICKSFTNF 57
Query: 248 CATFGNVVRVWLGSKLIVFLADADDIE--IILNSHVHIDKATEYKFFKPWLGEGLLISSG 421
+G V V+ G IV + ++ +I N + + G G++ S+G
Sbjct: 58 SKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNG 117
Query: 422 PKWR 433
+W+
Sbjct: 118 KRWK 121
>AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 35.9 bits (79), Expect = 0.13
Identities = 30/124 (24%), Positives = 54/124 (43%), Gaps = 3/124 (2%)
Frame = +2
Query: 71 YPLLGLTTAIWILYR-WQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGL 247
+ +L L + +L+ W+Q+ KL PGP P+PI GN L + I + +
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNMLQIDVKD---ICKSFTNF 57
Query: 248 CATFGNVVRVWLGSKLIVFLADADDIE--IILNSHVHIDKATEYKFFKPWLGEGLLISSG 421
+G V V+ G IV + ++ +I N + + G G++ S+G
Sbjct: 58 SKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNG 117
Query: 422 PKWR 433
+W+
Sbjct: 118 KRWK 121
>AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 35.9 bits (79), Expect = 0.13
Identities = 30/124 (24%), Positives = 54/124 (43%), Gaps = 3/124 (2%)
Frame = +2
Query: 71 YPLLGLTTAIWILYR-WQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGL 247
+ +L L + +L+ W+Q+ KL PGP P+PI GN L + I + +
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNMLQIDVKD---ICKSFTNF 57
Query: 248 CATFGNVVRVWLGSKLIVFLADADDIE--IILNSHVHIDKATEYKFFKPWLGEGLLISSG 421
+G V V+ G IV + ++ +I N + + G G++ S+G
Sbjct: 58 SKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNG 117
Query: 422 PKWR 433
+W+
Sbjct: 118 KRWK 121
>M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein.
Length = 480
Score = 35.1 bits (77), Expect = 0.22
Identities = 27/108 (25%), Positives = 46/108 (42%), Gaps = 2/108 (1%)
Frame = +2
Query: 116 WQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVVRVWLGSKL 295
W+Q+ KL PGP P+PI GN L + I + + +G V V+ G
Sbjct: 10 WRQSCRRRKLP---PGPTPLPIIGNMLQIDVKD---ICKSFTNFSKVYGPVFTVYFGMNP 63
Query: 296 IVFLADADDIE--IILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWR 433
IV + ++ +I N + + G G++ S+G +W+
Sbjct: 64 IVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWK 111
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 35.1 bits (77), Expect = 0.22
Identities = 31/153 (20%), Positives = 65/153 (42%), Gaps = 2/153 (1%)
Frame = +2
Query: 53 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQ 232
N V + LL ++ + LY + + +L +PGP P+P+ GN L+ + + +
Sbjct: 6 NLAVETWLLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVLSYRQ----GLWK 59
Query: 233 PRSGLCATFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGL 406
+ +G + + G ++ + D D I +L + T + P ++ +
Sbjct: 60 FDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECY-SVFTNRRSLGPVGFMKSAI 118
Query: 407 LISSGPKWRSHXXMIAPTFHINILKSFVGIFNQ 505
++ +W+ +++PTF LK I Q
Sbjct: 119 SLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQ 151
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 35.1 bits (77), Expect = 0.22
Identities = 35/153 (22%), Positives = 66/153 (43%), Gaps = 2/153 (1%)
Frame = +2
Query: 53 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQ 232
N V + LL ++ + LY + + KL +PGP P+P GNAL+ + +
Sbjct: 6 NLAVETWLLLAVSLILLYLYGTRTHGLFKKLG--IPGPTPLPFLGNALSFRKGYWTFDME 63
Query: 233 PRSGLCATFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGL 406
+ V ++ + ++ + D D I+ +L + T + F P ++ +
Sbjct: 64 ----CYKKYRKVWGIYDCQQPMLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAI 118
Query: 407 LISSGPKWRSHXXMIAPTFHINILKSFVGIFNQ 505
I+ +W+ +++PTF LK V I Q
Sbjct: 119 SIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQ 151
>DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P450,
family 3, subfamily A, polypeptide 5 protein.
Length = 347
Score = 35.1 bits (77), Expect = 0.22
Identities = 31/153 (20%), Positives = 65/153 (42%), Gaps = 2/153 (1%)
Frame = +2
Query: 53 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQ 232
N V + LL ++ + LY + + +L +PGP P+P+ GN L+ + + +
Sbjct: 6 NLAVETWLLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVLSYRQ----GLWK 59
Query: 233 PRSGLCATFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGL 406
+ +G + + G ++ + D D I +L + T + P ++ +
Sbjct: 60 FDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECY-SVFTNRRSLGPVGFMKSAI 118
Query: 407 LISSGPKWRSHXXMIAPTFHINILKSFVGIFNQ 505
++ +W+ +++PTF LK I Q
Sbjct: 119 SLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQ 151
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 35.1 bits (77), Expect = 0.22
Identities = 35/153 (22%), Positives = 66/153 (43%), Gaps = 2/153 (1%)
Frame = +2
Query: 53 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQ 232
N V + LL ++ + LY + + KL +PGP P+P GNAL+ + +
Sbjct: 6 NLAVETWLLLAVSLILLYLYGTRTHGLFKKLG--IPGPTPLPFLGNALSFRKGYWTFDME 63
Query: 233 PRSGLCATFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGL 406
+ V ++ + ++ + D D I+ +L + T + F P ++ +
Sbjct: 64 ----CYKKYRKVWGIYDCQQPMLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAI 118
Query: 407 LISSGPKWRSHXXMIAPTFHINILKSFVGIFNQ 505
I+ +W+ +++PTF LK V I Q
Sbjct: 119 SIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQ 151
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 35.1 bits (77), Expect = 0.22
Identities = 31/153 (20%), Positives = 65/153 (42%), Gaps = 2/153 (1%)
Frame = +2
Query: 53 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQ 232
N V + LL ++ + LY + + +L +PGP P+P+ GN L+ + + +
Sbjct: 6 NLAVETWLLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVLSYRQ----GLWK 59
Query: 233 PRSGLCATFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGL 406
+ +G + + G ++ + D D I +L + T + P ++ +
Sbjct: 60 FDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECY-SVFTNRRSLGPVGFMKSAI 118
Query: 407 LISSGPKWRSHXXMIAPTFHINILKSFVGIFNQ 505
++ +W+ +++PTF LK I Q
Sbjct: 119 SLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQ 151
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 35.1 bits (77), Expect = 0.22
Identities = 31/153 (20%), Positives = 65/153 (42%), Gaps = 2/153 (1%)
Frame = +2
Query: 53 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQ 232
N V + LL ++ + LY + + +L +PGP P+P+ GN L+ + + +
Sbjct: 6 NLAVETWLLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVLSYRQ----GLWK 59
Query: 233 PRSGLCATFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGL 406
+ +G + + G ++ + D D I +L + T + P ++ +
Sbjct: 60 FDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECY-SVFTNRRSLGPVGFMKSAI 118
Query: 407 LISSGPKWRSHXXMIAPTFHINILKSFVGIFNQ 505
++ +W+ +++PTF LK I Q
Sbjct: 119 SLAEDEEWKRIRPLLSPTFTSGKLKEMFPIIAQ 151
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 35.1 bits (77), Expect = 0.22
Identities = 35/153 (22%), Positives = 66/153 (43%), Gaps = 2/153 (1%)
Frame = +2
Query: 53 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQ 232
N V + LL ++ + LY + + KL +PGP P+P GNAL+ + +
Sbjct: 6 NLAVETWLLLAVSLILLYLYGTRTHGLFKKLG--IPGPTPLPFLGNALSFRKGYWTFDME 63
Query: 233 PRSGLCATFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGL 406
+ V ++ + ++ + D D I+ +L + T + F P ++ +
Sbjct: 64 ----CYKKYRKVWGIYDCQQPMLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAI 118
Query: 407 LISSGPKWRSHXXMIAPTFHINILKSFVGIFNQ 505
I+ +W+ +++PTF LK V I Q
Sbjct: 119 SIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQ 151
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 35.1 bits (77), Expect = 0.22
Identities = 35/153 (22%), Positives = 66/153 (43%), Gaps = 2/153 (1%)
Frame = +2
Query: 53 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQ 232
N V + LL ++ + LY + + KL +PGP P+P GNAL+ + +
Sbjct: 6 NLAVETWLLLAVSLILLYLYGTRTHGLFKKLG--IPGPTPLPFLGNALSFRKGYWTFDME 63
Query: 233 PRSGLCATFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGL 406
+ V ++ + ++ + D D I+ +L + T + F P ++ +
Sbjct: 64 ----CYKKYRKVWGIYDCQQPMLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAI 118
Query: 407 LISSGPKWRSHXXMIAPTFHINILKSFVGIFNQ 505
I+ +W+ +++PTF LK V I Q
Sbjct: 119 SIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQ 151
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 35.1 bits (77), Expect = 0.22
Identities = 31/153 (20%), Positives = 65/153 (42%), Gaps = 2/153 (1%)
Frame = +2
Query: 53 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQ 232
N V + LL ++ + LY + + +L +PGP P+P+ GN L+ + + +
Sbjct: 6 NLAVETWLLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVLSYRQ----GLWK 59
Query: 233 PRSGLCATFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGL 406
+ +G + + G ++ + D D I +L + T + P ++ +
Sbjct: 60 FDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECY-SVFTNRRSLGPVGFMKSAI 118
Query: 407 LISSGPKWRSHXXMIAPTFHINILKSFVGIFNQ 505
++ +W+ +++PTF LK I Q
Sbjct: 119 SLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQ 151
>M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein.
Length = 491
Score = 34.3 bits (75), Expect = 0.39
Identities = 28/118 (23%), Positives = 52/118 (44%), Gaps = 2/118 (1%)
Frame = +2
Query: 86 LTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGN 265
LT + +L + N+H L PGP P+P+ GN L + + +G+
Sbjct: 12 LTGLLLLLVQRHPNTH----DRLPPGPRPLPLLGNLLQMDRR---GLLKSFLRFREKYGD 64
Query: 266 VVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL-GEGLLISSGPKWR 433
V V LG + +V L + I E +++ + P+ G G++ ++G +W+
Sbjct: 65 VFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWK 122
>DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 34.3 bits (75), Expect = 0.39
Identities = 28/118 (23%), Positives = 52/118 (44%), Gaps = 2/118 (1%)
Frame = +2
Query: 86 LTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGN 265
LT + +L + N+H L PGP P+P+ GN L + + +G+
Sbjct: 12 LTGLLLLLVQRHPNTH----DRLPPGPRPLPLLGNLLQMDRR---GLLKSFLRFREKYGD 64
Query: 266 VVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL-GEGLLISSGPKWR 433
V V LG + +V L + I E +++ + P+ G G++ ++G +W+
Sbjct: 65 VFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWK 122
>BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 34.3 bits (75), Expect = 0.39
Identities = 28/118 (23%), Positives = 52/118 (44%), Gaps = 2/118 (1%)
Frame = +2
Query: 86 LTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGN 265
LT + +L + N+H L PGP P+P+ GN L + + +G+
Sbjct: 12 LTGLLLLLVQRHPNTH----DRLPPGPRPLPLLGNLLQMDRR---GLLKSFLRFREKYGD 64
Query: 266 VVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL-GEGLLISSGPKWR 433
V V LG + +V L + I E +++ + P+ G G++ ++G +W+
Sbjct: 65 VFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWK 122
>BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 34.3 bits (75), Expect = 0.39
Identities = 28/118 (23%), Positives = 52/118 (44%), Gaps = 2/118 (1%)
Frame = +2
Query: 86 LTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGN 265
LT + +L + N+H L PGP P+P+ GN L + + +G+
Sbjct: 12 LTGLLLLLVQRHPNTH----DRLPPGPRPLPLLGNLLQMDRR---GLLKSFLRFREKYGD 64
Query: 266 VVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL-GEGLLISSGPKWR 433
V V LG + +V L + I E +++ + P+ G G++ ++G +W+
Sbjct: 65 VFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWK 122
>AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6
protein.
Length = 491
Score = 34.3 bits (75), Expect = 0.39
Identities = 28/118 (23%), Positives = 52/118 (44%), Gaps = 2/118 (1%)
Frame = +2
Query: 86 LTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGN 265
LT + +L + N+H L PGP P+P+ GN L + + +G+
Sbjct: 12 LTGLLLLLVQRHPNTH----DRLPPGPRPLPLLGNLLQMDRR---GLLKSFLRFREKYGD 64
Query: 266 VVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL-GEGLLISSGPKWR 433
V V LG + +V L + I E +++ + P+ G G++ ++G +W+
Sbjct: 65 VFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWK 122
>AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein.
Length = 491
Score = 34.3 bits (75), Expect = 0.39
Identities = 28/118 (23%), Positives = 52/118 (44%), Gaps = 2/118 (1%)
Frame = +2
Query: 86 LTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGN 265
LT + +L + N+H L PGP P+P+ GN L + + +G+
Sbjct: 12 LTGLLLLLVQRHPNTH----DRLPPGPRPLPLLGNLLQMDRR---GLLKSFLRFREKYGD 64
Query: 266 VVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL-GEGLLISSGPKWR 433
V V LG + +V L + I E +++ + P+ G G++ ++G +W+
Sbjct: 65 VFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWK 122
>BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family 2,
subfamily S, polypeptide 1 protein.
Length = 504
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/97 (24%), Positives = 41/97 (42%), Gaps = 3/97 (3%)
Frame = +2
Query: 152 LLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVVRVWLGS-KLIVFLADADDIE 328
L PGP P+P+ GN L + + + L +G V ++LG + +V L + +
Sbjct: 32 LPPGPTPLPLLGNLL---QLRPGALYSGLMRLSKKYGPVFTIYLGPWRPVVVLVGQEAVR 88
Query: 329 IILNSHVH--IDKATEYKFFKPWLGEGLLISSGPKWR 433
L + T + G G+ S+G +WR
Sbjct: 89 EALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWR 125
>AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein.
Length = 504
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/97 (24%), Positives = 41/97 (42%), Gaps = 3/97 (3%)
Frame = +2
Query: 152 LLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVVRVWLGS-KLIVFLADADDIE 328
L PGP P+P+ GN L + + + L +G V ++LG + +V L + +
Sbjct: 32 LPPGPTPLPLLGNLL---QLRPGALYSGLMRLSKKYGPVFTIYLGPWRPVVVLVGQEAVR 88
Query: 329 IILNSHVH--IDKATEYKFFKPWLGEGLLISSGPKWR 433
L + T + G G+ S+G +WR
Sbjct: 89 EALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWR 125
>AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens
cDNA FLJ14699 fis, clone NT2RP2006571, moderately
similar to CYTOCHROME P450 2G1 (EC 1.14.14.1). ).
Length = 564
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/97 (24%), Positives = 41/97 (42%), Gaps = 3/97 (3%)
Frame = +2
Query: 152 LLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVVRVWLGS-KLIVFLADADDIE 328
L PGP P+P+ GN L + + + L +G V ++LG + +V L + +
Sbjct: 32 LPPGPTPLPLLGNLL---QLRPGALYSGLMRLSKKYGPVFTIYLGPWRPVVVLVGQEAVR 88
Query: 329 IILNSHVH--IDKATEYKFFKPWLGEGLLISSGPKWR 433
L + T + G G+ S+G +WR
Sbjct: 89 EALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWR 125
>AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1
protein.
Length = 504
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/97 (24%), Positives = 41/97 (42%), Gaps = 3/97 (3%)
Frame = +2
Query: 152 LLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVVRVWLGS-KLIVFLADADDIE 328
L PGP P+P+ GN L + + + L +G V ++LG + +V L + +
Sbjct: 32 LPPGPTPLPLLGNLL---QLRPGALYSGLMRLSKKYGPVFTIYLGPWRPVVVLVGQEAVR 88
Query: 329 IILNSHVH--IDKATEYKFFKPWLGEGLLISSGPKWR 433
L + T + G G+ S+G +WR
Sbjct: 89 EALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWR 125
>M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein.
Length = 462
Score = 31.9 bits (69), Expect = 2.1
Identities = 24/96 (25%), Positives = 41/96 (42%), Gaps = 2/96 (2%)
Frame = +2
Query: 152 LLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVVRVWLGSKLIVFLADADDIE- 328
L PGP P+PI GN L + I + + +G V V+ G IV + ++
Sbjct: 1 LPPGPTPLPIIGNMLQIDVKD---ICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKE 57
Query: 329 -IILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWR 433
+I N + + G G++ S+G +W+
Sbjct: 58 ALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWK 93
>BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family 2,
subfamily W, polypeptide 1 protein.
Length = 490
Score = 31.9 bits (69), Expect = 2.1
Identities = 27/105 (25%), Positives = 41/105 (39%), Gaps = 2/105 (1%)
Frame = +2
Query: 158 PGPAPIPIFGNALTXHEEKSPRISQPRSGLCATFGNVVRVWLGSKLIVFLADADDIEIIL 337
PGP P+P+ GN H + + + L +G V V LG + V L + ++ L
Sbjct: 33 PGPRPLPLVGN---LHLLRLSQQDRSLMELSERYGPVFTVHLGRQKTVVLTGFEAVKEAL 89
Query: 338 --NSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHXXMIAPTFH 466
D+ F G G+ SSG +WR+ H
Sbjct: 90 AGPGQELADRPPIAIFQLIQRGGGIFFSSGARWRAARQFTVRALH 134
>X54807-1|CAA38578.1| 56|Homo sapiens unspecific monooxygenase
protein.
Length = 56
Score = 30.7 bits (66), Expect = 4.8
Identities = 16/43 (37%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Frame = +2
Query: 71 YPLLGLTTAIWILYR-WQQNSHMHKLAELLPGPAPIPIFGNAL 196
+ +L L + +L+ W+Q+ KL PGP P+PI GN L
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNML 43
>BC139737-1|AAI39738.1| 263|Homo sapiens transmembrane protein 56
protein.
Length = 263
Score = 30.7 bits (66), Expect = 4.8
Identities = 11/25 (44%), Positives = 18/25 (72%)
Frame = -2
Query: 576 THVIMYVKCFSDFRFQLLYHVVTFW 502
T +++ V C S F FQLL++ V++W
Sbjct: 5 TKLLISVTCISFFTFQLLFYFVSYW 29
>BC004367-1|AAH04367.1| 313|Homo sapiens potassium channel,
subfamily K, member 6 protein.
Length = 313
Score = 30.7 bits (66), Expect = 4.8
Identities = 16/44 (36%), Positives = 22/44 (50%)
Frame = +2
Query: 62 VIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNA 193
V Y LGL + +L ++ S +H L EL+ P P P NA
Sbjct: 238 VTVYLFLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNA 281
>AK222545-1|BAD96265.1| 313|Homo sapiens potassium channel,
subfamily K, member 6 variant protein.
Length = 313
Score = 30.7 bits (66), Expect = 4.8
Identities = 16/44 (36%), Positives = 22/44 (50%)
Frame = +2
Query: 62 VIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNA 193
V Y LGL + +L ++ S +H L EL+ P P P NA
Sbjct: 238 VTVYLFLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNA 281
>AK056404-1|BAB71177.1| 263|Homo sapiens protein ( Homo sapiens
cDNA FLJ31842 fis, clone NT2RP7000259. ).
Length = 263
Score = 30.7 bits (66), Expect = 4.8
Identities = 11/25 (44%), Positives = 18/25 (72%)
Frame = -2
Query: 576 THVIMYVKCFSDFRFQLLYHVVTFW 502
T +++ V C S F FQLL++ V++W
Sbjct: 5 TKLLISVTCISFFTFQLLFYFVSYW 29
>AJ297404-1|CAC15489.1| 313|Homo sapiens potassium channel,
subfamily K, member 6 (TWIK-2) protein.
Length = 313
Score = 30.7 bits (66), Expect = 4.8
Identities = 16/44 (36%), Positives = 22/44 (50%)
Frame = +2
Query: 62 VIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNA 193
V Y LGL + +L ++ S +H L EL+ P P P NA
Sbjct: 238 VTVYLFLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNA 281
>AF281303-1|AAG10507.1| 179|Homo sapiens 2P domain K+ channel
TWIK-2 protein.
Length = 179
Score = 30.7 bits (66), Expect = 4.8
Identities = 16/44 (36%), Positives = 22/44 (50%)
Frame = +2
Query: 62 VIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNA 193
V Y LGL + +L ++ S +H L EL+ P P P NA
Sbjct: 104 VTVYLFLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNA 147
>AF281302-1|AAG10506.1| 313|Homo sapiens 2P domain K+ channel
TWIK-2 protein.
Length = 313
Score = 30.7 bits (66), Expect = 4.8
Identities = 16/44 (36%), Positives = 22/44 (50%)
Frame = +2
Query: 62 VIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNA 193
V Y LGL + +L ++ S +H L EL+ P P P NA
Sbjct: 238 VTVYLFLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNA 281
>AF134149-1|AAD22980.1| 313|Homo sapiens 2-pore K+ channel subunit
TOSS protein.
Length = 313
Score = 30.7 bits (66), Expect = 4.8
Identities = 16/44 (36%), Positives = 22/44 (50%)
Frame = +2
Query: 62 VIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNA 193
V Y LGL + +L ++ S +H L EL+ P P P NA
Sbjct: 238 VTVYLFLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNA 281
>AF117708-1|AAD24000.1| 313|Homo sapiens tandem pore domain
potassium channel TWIK-2 protein.
Length = 313
Score = 30.7 bits (66), Expect = 4.8
Identities = 16/44 (36%), Positives = 22/44 (50%)
Frame = +2
Query: 62 VIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNA 193
V Y LGL + +L ++ S +H L EL+ P P P NA
Sbjct: 238 VTVYLFLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNA 281
>AK024290-1|BAB14875.1| 590|Homo sapiens protein ( Homo sapiens
cDNA FLJ14228 fis, clone NT2RP3004148. ).
Length = 590
Score = 30.3 bits (65), Expect = 6.3
Identities = 13/28 (46%), Positives = 18/28 (64%)
Frame = +2
Query: 32 ETEGYHVNSRVIFYPLLGLTTAIWILYR 115
E + V +R +FYPLLGL A+ + YR
Sbjct: 372 EVQRKEVQARAVFYPLLGLGGAVNMCYR 399
>AB040956-1|BAA96047.1| 687|Homo sapiens KIAA1523 protein protein.
Length = 687
Score = 30.3 bits (65), Expect = 6.3
Identities = 13/28 (46%), Positives = 18/28 (64%)
Frame = +2
Query: 32 ETEGYHVNSRVIFYPLLGLTTAIWILYR 115
E + V +R +FYPLLGL A+ + YR
Sbjct: 469 EVQRKEVQARAVFYPLLGLGGAVNMCYR 496
>DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 29.9 bits (64), Expect = 8.3
Identities = 37/153 (24%), Positives = 60/153 (39%), Gaps = 6/153 (3%)
Frame = +2
Query: 80 LGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHEEKSPRISQPRSGLCATF 259
L + AI++L + H A PGP P+P GN L + +P L F
Sbjct: 9 LAVIVAIFLLLVDLMHRHQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQ---LRRRF 65
Query: 260 GNVVRVWLGSKLIVFLADADDIEIILNSHVH--IDK----ATEYKFFKPWLGEGLLISSG 421
G+V + L +V L + L +H D+ T+ F P L G
Sbjct: 66 GDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYG 125
Query: 422 PKWRSHXXMIAPTFHINILKSFVGIFNQNVTTW 520
P WR F ++ L++ +G+ +++ W
Sbjct: 126 PAWREQR-----RFSVSTLRN-LGLGKKSLEQW 152
>AF280107-4|AAG32288.1| 106|Homo sapiens cytochrome P450
polypeptide 5 protein.
Length = 106
Score = 29.9 bits (64), Expect = 8.3
Identities = 15/52 (28%), Positives = 27/52 (51%)
Frame = +2
Query: 53 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTXHE 208
N V + LL ++ + LY + + +L +PGP P+P+ GN L+ +
Sbjct: 6 NLAVETWLLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVLSYRQ 55
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 102,965,318
Number of Sequences: 237096
Number of extensions: 2306371
Number of successful extensions: 8173
Number of sequences better than 10.0: 198
Number of HSP's better than 10.0 without gapping: 7903
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8122
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7366354010
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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