Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= e96h0619
(770 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U48730-1|AAC50485.2| 787|Homo sapiens transcription factor Stat... 119 1e-26
U47686-1|AAC50491.1| 787|Homo sapiens signal transducer and act... 119 1e-26
BC065227-1|AAH65227.1| 787|Homo sapiens signal transducer and a... 119 1e-26
AJ412888-1|CAD19638.1| 787|Homo sapiens protein ( Homo sapiens ... 119 1e-26
U43185-1|AAB06589.1| 794|Homo sapiens Stat5A protein. 118 3e-26
L41142-1|AAA73962.1| 794|Homo sapiens signal transducer and act... 118 3e-26
DQ471288-1|ABF17939.1| 764|Homo sapiens signal transducer and a... 118 3e-26
BC027036-1|AAH27036.1| 794|Homo sapiens signal transducer and a... 118 3e-26
AJ412878-1|CAD19637.1| 791|Homo sapiens signal transducer and a... 118 3e-26
AB208920-1|BAD92157.1| 788|Homo sapiens signal transducer and a... 118 3e-26
AB208972-1|BAD92209.1| 765|Homo sapiens signal transducer and a... 97 8e-20
U16031-1|AAA57193.1| 847|Homo sapiens IL-4 Stat protein. 96 1e-19
BC075852-1|AAH75852.1| 847|Homo sapiens signal transducer and a... 96 1e-19
AF417842-1|AAL06595.1| 847|Homo sapiens signal transducer and a... 96 1e-19
AF067575-1|AAC67525.1| 847|Homo sapiens signal transducer and a... 96 1e-19
AB103089-1|BAD89432.1| 673|Homo sapiens signal transducer and a... 96 1e-19
BT007380-1|AAP36044.1| 679|Homo sapiens signal transducer and a... 92 2e-18
L78440-1|AAB05605.1| 748|Homo sapiens signal transducer and act... 71 6e-12
BC031212-1|AAH31212.1| 748|Homo sapiens STAT4 protein protein. 71 6e-12
AF423072-1|AAL12164.1| 652|Homo sapiens signal transducer and a... 71 6e-12
AC067945-3|AAY24184.1| 657|Homo sapiens unknown protein. 71 6e-12
AB209043-1|BAD92280.1| 332|Homo sapiens signal transducer and a... 71 6e-12
M97935-1|AAB64012.1| 750|Homo sapiens transcription factor ISGF... 60 9e-09
BT007241-1|AAP35905.1| 712|Homo sapiens signal transducer and a... 60 9e-09
BC002704-1|AAH02704.1| 712|Homo sapiens signal transducer and a... 60 9e-09
AY865620-1|AAW56072.1| 750|Homo sapiens signal transducer and a... 60 9e-09
AC067945-2|AAY24183.1| 750|Homo sapiens unknown protein. 60 9e-09
BC014482-1|AAH14482.1| 770|Homo sapiens signal transducer and a... 57 8e-08
BC000627-1|AAH00627.1| 769|Homo sapiens signal transducer and a... 57 8e-08
AY572796-1|AAS66986.1| 769|Homo sapiens signal transducer and a... 57 8e-08
AJ012463-1|CAA10032.1| 770|Homo sapiens transcription factor pr... 57 8e-08
L29277-1|AAA58374.1| 770|Homo sapiens DNA-binding protein protein. 55 2e-07
U18671-1|AAA98760.1| 851|Homo sapiens Stat2 protein. 48 5e-05
BC051284-1|AAH51284.1| 851|Homo sapiens signal transducer and a... 48 5e-05
AY525126-1|AAS00091.1| 851|Homo sapiens signal transducer and a... 48 5e-05
BX640607-1|CAE45713.1| 448|Homo sapiens hypothetical protein pr... 47 7e-05
AF029311-1|AAB84254.1| 141|Homo sapiens signal transducer and a... 46 2e-04
BC006092-1|AAH06092.1| 577|Homo sapiens Unknown (protein for IM... 46 2e-04
BC150248-1|AAI50249.1| 992|Homo sapiens ELKS/RAB6-interacting/C... 31 6.0
BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 31 6.0
BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 31 6.0
BC068006-1|AAH68006.1| 627|Homo sapiens ERC1 protein protein. 31 6.0
AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein. 31 6.0
AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein. 31 6.0
AB053469-1|BAC54108.1| 720|Homo sapiens ELKS gamma protein. 31 6.0
AB053468-1|BAC54107.1| 992|Homo sapiens ELKS beta protein. 31 6.0
AB029004-1|BAA83033.2| 1003|Homo sapiens KIAA1081 protein protein. 31 6.0
AB015617-1|BAA88763.1| 948|Homo sapiens ELKS protein. 31 6.0
BC150172-1|AAI50173.1| 929|Homo sapiens protocadherin gamma sub... 30 8.0
AF110315-1|AAD13107.1| 388|Homo sapiens unknown protein. 30 8.0
>U48730-1|AAC50485.2| 787|Homo sapiens transcription factor Stat5b
protein.
Length = 787
Score = 119 bits (287), Expect = 1e-26
Identities = 54/85 (63%), Positives = 68/85 (80%)
Frame = +1
Query: 13 TAQRHFRNMQLRKIKRAEKKGTESVMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIV 192
T HFRNM L++IKR++++G ESV +EK T+LF+SQF+VGG ELVFQV TLSLPVVVIV
Sbjct: 411 TLSAHFRNMSLKRIKRSDRRGAESVTEEKFTILFESQFSVGGNELVFQVKTLSLPVVVIV 470
Query: 193 HGNQEPHGWATVTWDNAFSPPAGCP 267
HG+Q+ + ATV WDNAF+ P P
Sbjct: 471 HGSQDNNATATVLWDNAFAEPGRVP 495
Score = 103 bits (247), Expect = 7e-22
Identities = 58/148 (39%), Positives = 81/148 (54%), Gaps = 2/148 (1%)
Frame = +3
Query: 252 PGRVPFAVPDKVTWGQLAETLSLKFSS--ATGGSLSEDNLRFLAEKIFRTSLPLNTMELN 425
PGRVPFAVPDKV W QL E L++KF + + L+++NL FLA+K+F S + + +
Sbjct: 491 PGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNNS-SSHLEDYS 549
Query: 426 AMAVSWTQFCKDALPERNFTFWEWFYMVSRSPGTTCGPCGATA**WASYRRSKLRICCPS 605
++VSW+QF ++ LP RN+TFW+WF V P + + +
Sbjct: 550 GLSVSWSQFNRENLPGRNYTFWQWFDGVMEVLKKHLKPHWNDGAILGFVNKQQAHDLLIN 609
Query: 606 VRPGPSCCGSSDSELGGITIAWTGDGNE 689
G SDSE+GGITIAW D E
Sbjct: 610 KPDGTFLLRFSDSEIGGITIAWKFDSQE 637
Score = 46.4 bits (105), Expect = 1e-04
Identities = 20/41 (48%), Positives = 28/41 (68%)
Frame = +2
Query: 512 KVTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
+V + +L+ W D I+GF+ K+QA D+L P GTFLLRF
Sbjct: 579 EVLKKHLKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRF 619
>U47686-1|AAC50491.1| 787|Homo sapiens signal transducer and
activator of transcription Stat5B protein.
Length = 787
Score = 119 bits (287), Expect = 1e-26
Identities = 54/85 (63%), Positives = 68/85 (80%)
Frame = +1
Query: 13 TAQRHFRNMQLRKIKRAEKKGTESVMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIV 192
T HFRNM L++IKR++++G ESV +EK T+LF+SQF+VGG ELVFQV TLSLPVVVIV
Sbjct: 411 TLSAHFRNMSLKRIKRSDRRGAESVTEEKFTILFESQFSVGGNELVFQVKTLSLPVVVIV 470
Query: 193 HGNQEPHGWATVTWDNAFSPPAGCP 267
HG+Q+ + ATV WDNAF+ P P
Sbjct: 471 HGSQDNNATATVLWDNAFAEPGRVP 495
Score = 103 bits (247), Expect = 7e-22
Identities = 58/148 (39%), Positives = 81/148 (54%), Gaps = 2/148 (1%)
Frame = +3
Query: 252 PGRVPFAVPDKVTWGQLAETLSLKFSS--ATGGSLSEDNLRFLAEKIFRTSLPLNTMELN 425
PGRVPFAVPDKV W QL E L++KF + + L+++NL FLA+K+F S + + +
Sbjct: 491 PGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNNS-SSHLEDYS 549
Query: 426 AMAVSWTQFCKDALPERNFTFWEWFYMVSRSPGTTCGPCGATA**WASYRRSKLRICCPS 605
++VSW+QF ++ LP RN+TFW+WF V P + + +
Sbjct: 550 GLSVSWSQFNRENLPGRNYTFWQWFDGVMEVLKKHLKPHWNDGAILGFVNKQQAHDLLIN 609
Query: 606 VRPGPSCCGSSDSELGGITIAWTGDGNE 689
G SDSE+GGITIAW D E
Sbjct: 610 KPDGTFLLRFSDSEIGGITIAWKFDSQE 637
Score = 46.4 bits (105), Expect = 1e-04
Identities = 20/41 (48%), Positives = 28/41 (68%)
Frame = +2
Query: 512 KVTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
+V + +L+ W D I+GF+ K+QA D+L P GTFLLRF
Sbjct: 579 EVLKKHLKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRF 619
>BC065227-1|AAH65227.1| 787|Homo sapiens signal transducer and
activator of transcription 5B protein.
Length = 787
Score = 119 bits (287), Expect = 1e-26
Identities = 54/85 (63%), Positives = 68/85 (80%)
Frame = +1
Query: 13 TAQRHFRNMQLRKIKRAEKKGTESVMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIV 192
T HFRNM L++IKR++++G ESV +EK T+LF+SQF+VGG ELVFQV TLSLPVVVIV
Sbjct: 411 TLSAHFRNMSLKRIKRSDRRGAESVTEEKFTILFESQFSVGGNELVFQVKTLSLPVVVIV 470
Query: 193 HGNQEPHGWATVTWDNAFSPPAGCP 267
HG+Q+ + ATV WDNAF+ P P
Sbjct: 471 HGSQDNNATATVLWDNAFAEPGRVP 495
Score = 103 bits (247), Expect = 7e-22
Identities = 58/148 (39%), Positives = 81/148 (54%), Gaps = 2/148 (1%)
Frame = +3
Query: 252 PGRVPFAVPDKVTWGQLAETLSLKFSS--ATGGSLSEDNLRFLAEKIFRTSLPLNTMELN 425
PGRVPFAVPDKV W QL E L++KF + + L+++NL FLA+K+F S + + +
Sbjct: 491 PGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNNS-SSHLEDYS 549
Query: 426 AMAVSWTQFCKDALPERNFTFWEWFYMVSRSPGTTCGPCGATA**WASYRRSKLRICCPS 605
++VSW+QF ++ LP RN+TFW+WF V P + + +
Sbjct: 550 GLSVSWSQFNRENLPGRNYTFWQWFDGVMEVLKKHLKPHWNDGAILGFVNKQQAHDLLIN 609
Query: 606 VRPGPSCCGSSDSELGGITIAWTGDGNE 689
G SDSE+GGITIAW D E
Sbjct: 610 KPDGTFLLRFSDSEIGGITIAWKFDSQE 637
Score = 46.4 bits (105), Expect = 1e-04
Identities = 20/41 (48%), Positives = 28/41 (68%)
Frame = +2
Query: 512 KVTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
+V + +L+ W D I+GF+ K+QA D+L P GTFLLRF
Sbjct: 579 EVLKKHLKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRF 619
>AJ412888-1|CAD19638.1| 787|Homo sapiens protein ( Homo sapiens
partial STAT5B gene for signal transducer and
activatorof transcription 5B, exon 2 and joined CDS. ).
Length = 787
Score = 119 bits (287), Expect = 1e-26
Identities = 54/85 (63%), Positives = 68/85 (80%)
Frame = +1
Query: 13 TAQRHFRNMQLRKIKRAEKKGTESVMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIV 192
T HFRNM L++IKR++++G ESV +EK T+LF+SQF+VGG ELVFQV TLSLPVVVIV
Sbjct: 411 TLSAHFRNMSLKRIKRSDRRGAESVTEEKFTILFESQFSVGGNELVFQVKTLSLPVVVIV 470
Query: 193 HGNQEPHGWATVTWDNAFSPPAGCP 267
HG+Q+ + ATV WDNAF+ P P
Sbjct: 471 HGSQDNNATATVLWDNAFAEPGRVP 495
Score = 103 bits (247), Expect = 7e-22
Identities = 58/148 (39%), Positives = 81/148 (54%), Gaps = 2/148 (1%)
Frame = +3
Query: 252 PGRVPFAVPDKVTWGQLAETLSLKFSS--ATGGSLSEDNLRFLAEKIFRTSLPLNTMELN 425
PGRVPFAVPDKV W QL E L++KF + + L+++NL FLA+K+F S + + +
Sbjct: 491 PGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNNS-SSHLEDYS 549
Query: 426 AMAVSWTQFCKDALPERNFTFWEWFYMVSRSPGTTCGPCGATA**WASYRRSKLRICCPS 605
++VSW+QF ++ LP RN+TFW+WF V P + + +
Sbjct: 550 GLSVSWSQFNRENLPGRNYTFWQWFDGVMEVLKKHLKPHWNDGAILGFVNKQQAHDLLIN 609
Query: 606 VRPGPSCCGSSDSELGGITIAWTGDGNE 689
G SDSE+GGITIAW D E
Sbjct: 610 KPDGTFLLRFSDSEIGGITIAWKFDSQE 637
Score = 46.4 bits (105), Expect = 1e-04
Identities = 20/41 (48%), Positives = 28/41 (68%)
Frame = +2
Query: 512 KVTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
+V + +L+ W D I+GF+ K+QA D+L P GTFLLRF
Sbjct: 579 EVLKKHLKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRF 619
>U43185-1|AAB06589.1| 794|Homo sapiens Stat5A protein.
Length = 794
Score = 118 bits (283), Expect = 3e-26
Identities = 54/85 (63%), Positives = 67/85 (78%)
Frame = +1
Query: 13 TAQRHFRNMQLRKIKRAEKKGTESVMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIV 192
T HFRNM L++IKRA+++G ESV +EK T+LF+SQF+VG ELVFQV TLSLPVVVIV
Sbjct: 411 TLSAHFRNMSLKRIKRADRRGAESVTEEKFTVLFESQFSVGSNELVFQVKTLSLPVVVIV 470
Query: 193 HGNQEPHGWATVTWDNAFSPPAGCP 267
HG+Q+ + ATV WDNAF+ P P
Sbjct: 471 HGSQDHNATATVLWDNAFAEPGRVP 495
Score = 98.7 bits (235), Expect = 2e-20
Identities = 57/148 (38%), Positives = 80/148 (54%), Gaps = 2/148 (1%)
Frame = +3
Query: 252 PGRVPFAVPDKVTWGQLAETLSLKFSS--ATGGSLSEDNLRFLAEKIFRTSLPLNTMELN 425
PGRVPFAVPDKV W QL E L++KF + + L+++NL FLA+K+F S + + +
Sbjct: 491 PGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNNS-SSHLEDYS 549
Query: 426 AMAVSWTQFCKDALPERNFTFWEWFYMVSRSPGTTCGPCGATA**WASYRRSKLRICCPS 605
++VSW+QF ++ LP N+TFW+WF V P + + +
Sbjct: 550 GLSVSWSQFNRENLPGWNYTFWQWFDGVMEVLKKHHKPHWNDGAILGFVNKQQAHDLLIN 609
Query: 606 VRPGPSCCGSSDSELGGITIAWTGDGNE 689
G SDSE+GGITIAW D E
Sbjct: 610 KPDGTFLLRFSDSEIGGITIAWKFDSPE 637
Score = 43.6 bits (98), Expect = 8e-04
Identities = 19/41 (46%), Positives = 27/41 (65%)
Frame = +2
Query: 512 KVTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
+V + + + W D I+GF+ K+QA D+L P GTFLLRF
Sbjct: 579 EVLKKHHKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRF 619
>L41142-1|AAA73962.1| 794|Homo sapiens signal transducer and
activator of transcrption protein.
Length = 794
Score = 118 bits (283), Expect = 3e-26
Identities = 54/85 (63%), Positives = 67/85 (78%)
Frame = +1
Query: 13 TAQRHFRNMQLRKIKRAEKKGTESVMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIV 192
T HFRNM L++IKRA+++G ESV +EK T+LF+SQF+VG ELVFQV TLSLPVVVIV
Sbjct: 411 TLSAHFRNMSLKRIKRADRRGAESVTEEKFTVLFESQFSVGSNELVFQVKTLSLPVVVIV 470
Query: 193 HGNQEPHGWATVTWDNAFSPPAGCP 267
HG+Q+ + ATV WDNAF+ P P
Sbjct: 471 HGSQDHNATATVLWDNAFAEPGRVP 495
Score = 98.7 bits (235), Expect = 2e-20
Identities = 57/148 (38%), Positives = 80/148 (54%), Gaps = 2/148 (1%)
Frame = +3
Query: 252 PGRVPFAVPDKVTWGQLAETLSLKFSS--ATGGSLSEDNLRFLAEKIFRTSLPLNTMELN 425
PGRVPFAVPDKV W QL E L++KF + + L+++NL FLA+K+F S + + +
Sbjct: 491 PGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNNS-SSHLEDYS 549
Query: 426 AMAVSWTQFCKDALPERNFTFWEWFYMVSRSPGTTCGPCGATA**WASYRRSKLRICCPS 605
++VSW+QF ++ LP N+TFW+WF V P + + +
Sbjct: 550 GLSVSWSQFNRENLPGWNYTFWQWFDGVMEVLKKHHKPHWNDGAILGFVNKQQAHDLLIN 609
Query: 606 VRPGPSCCGSSDSELGGITIAWTGDGNE 689
G SDSE+GGITIAW D E
Sbjct: 610 KPDGTFLLRFSDSEIGGITIAWKFDSPE 637
Score = 43.6 bits (98), Expect = 8e-04
Identities = 19/41 (46%), Positives = 27/41 (65%)
Frame = +2
Query: 512 KVTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
+V + + + W D I+GF+ K+QA D+L P GTFLLRF
Sbjct: 579 EVLKKHHKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRF 619
>DQ471288-1|ABF17939.1| 764|Homo sapiens signal transducer and
activator of transcription 5A variant delta5 protein.
Length = 764
Score = 118 bits (283), Expect = 3e-26
Identities = 54/85 (63%), Positives = 67/85 (78%)
Frame = +1
Query: 13 TAQRHFRNMQLRKIKRAEKKGTESVMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIV 192
T HFRNM L++IKRA+++G ESV +EK T+LF+SQF+VG ELVFQV TLSLPVVVIV
Sbjct: 381 TLSAHFRNMSLKRIKRADRRGAESVTEEKFTVLFESQFSVGSNELVFQVKTLSLPVVVIV 440
Query: 193 HGNQEPHGWATVTWDNAFSPPAGCP 267
HG+Q+ + ATV WDNAF+ P P
Sbjct: 441 HGSQDHNATATVLWDNAFAEPGRVP 465
Score = 98.7 bits (235), Expect = 2e-20
Identities = 57/148 (38%), Positives = 80/148 (54%), Gaps = 2/148 (1%)
Frame = +3
Query: 252 PGRVPFAVPDKVTWGQLAETLSLKFSS--ATGGSLSEDNLRFLAEKIFRTSLPLNTMELN 425
PGRVPFAVPDKV W QL E L++KF + + L+++NL FLA+K+F S + + +
Sbjct: 461 PGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNNS-SSHLEDYS 519
Query: 426 AMAVSWTQFCKDALPERNFTFWEWFYMVSRSPGTTCGPCGATA**WASYRRSKLRICCPS 605
++VSW+QF ++ LP N+TFW+WF V P + + +
Sbjct: 520 GLSVSWSQFNRENLPGWNYTFWQWFDGVMEVLKKHHKPHWNDGAILGFVNKQQAHDLLIN 579
Query: 606 VRPGPSCCGSSDSELGGITIAWTGDGNE 689
G SDSE+GGITIAW D E
Sbjct: 580 KPDGTFLLRFSDSEIGGITIAWKFDSPE 607
Score = 43.6 bits (98), Expect = 8e-04
Identities = 19/41 (46%), Positives = 27/41 (65%)
Frame = +2
Query: 512 KVTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
+V + + + W D I+GF+ K+QA D+L P GTFLLRF
Sbjct: 549 EVLKKHHKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRF 589
>BC027036-1|AAH27036.1| 794|Homo sapiens signal transducer and
activator of transcription 5A protein.
Length = 794
Score = 118 bits (283), Expect = 3e-26
Identities = 54/85 (63%), Positives = 67/85 (78%)
Frame = +1
Query: 13 TAQRHFRNMQLRKIKRAEKKGTESVMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIV 192
T HFRNM L++IKRA+++G ESV +EK T+LF+SQF+VG ELVFQV TLSLPVVVIV
Sbjct: 411 TLSAHFRNMSLKRIKRADRRGAESVTEEKFTVLFESQFSVGSNELVFQVKTLSLPVVVIV 470
Query: 193 HGNQEPHGWATVTWDNAFSPPAGCP 267
HG+Q+ + ATV WDNAF+ P P
Sbjct: 471 HGSQDHNATATVLWDNAFAEPGRVP 495
Score = 98.7 bits (235), Expect = 2e-20
Identities = 57/148 (38%), Positives = 80/148 (54%), Gaps = 2/148 (1%)
Frame = +3
Query: 252 PGRVPFAVPDKVTWGQLAETLSLKFSS--ATGGSLSEDNLRFLAEKIFRTSLPLNTMELN 425
PGRVPFAVPDKV W QL E L++KF + + L+++NL FLA+K+F S + + +
Sbjct: 491 PGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNNS-SSHLEDYS 549
Query: 426 AMAVSWTQFCKDALPERNFTFWEWFYMVSRSPGTTCGPCGATA**WASYRRSKLRICCPS 605
++VSW+QF ++ LP N+TFW+WF V P + + +
Sbjct: 550 GLSVSWSQFNRENLPGWNYTFWQWFDGVMEVLKKHHKPHWNDGAILGFVNKQQAHDLLIN 609
Query: 606 VRPGPSCCGSSDSELGGITIAWTGDGNE 689
G SDSE+GGITIAW D E
Sbjct: 610 KPDGTFLLRFSDSEIGGITIAWKFDSPE 637
Score = 43.6 bits (98), Expect = 8e-04
Identities = 19/41 (46%), Positives = 27/41 (65%)
Frame = +2
Query: 512 KVTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
+V + + + W D I+GF+ K+QA D+L P GTFLLRF
Sbjct: 579 EVLKKHHKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRF 619
>AJ412878-1|CAD19637.1| 791|Homo sapiens signal transducer and
activator of transcription 5A protein.
Length = 791
Score = 118 bits (283), Expect = 3e-26
Identities = 54/85 (63%), Positives = 67/85 (78%)
Frame = +1
Query: 13 TAQRHFRNMQLRKIKRAEKKGTESVMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIV 192
T HFRNM L++IKRA+++G ESV +EK T+LF+SQF+VG ELVFQV TLSLPVVVIV
Sbjct: 411 TLSAHFRNMSLKRIKRADRRGAESVTEEKFTVLFESQFSVGSNELVFQVKTLSLPVVVIV 470
Query: 193 HGNQEPHGWATVTWDNAFSPPAGCP 267
HG+Q+ + ATV WDNAF+ P P
Sbjct: 471 HGSQDHNATATVLWDNAFAEPGRVP 495
Score = 98.3 bits (234), Expect = 3e-20
Identities = 60/148 (40%), Positives = 81/148 (54%), Gaps = 2/148 (1%)
Frame = +3
Query: 252 PGRVPFAVPDKVTWGQLAETLSLKFSS--ATGGSLSEDNLRFLAEKIFRTSLPLNTMELN 425
PGRVPFAVPDKV W QL E L++KF + + L+++NL FLA+K+F S + + +
Sbjct: 491 PGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNNS-SSHLEDYS 549
Query: 426 AMAVSWTQFCKDALPERNFTFWEWFYMVSRSPGTTCGPCGATA**WASYRRSKLRICCPS 605
++VSW+QF ++ LP N+TFW+WF V P + L I P
Sbjct: 550 GLSVSWSQFNRENLPGWNYTFWQWFDGVMEVLKKHHKPHWNDGGFVNKQQAHDLLINKPD 609
Query: 606 VRPGPSCCGSSDSELGGITIAWTGDGNE 689
G SDSE+GGITIAW D E
Sbjct: 610 ---GTFLLRFSDSEIGGITIAWKFDSPE 634
Score = 35.9 bits (79), Expect = 0.16
Identities = 15/24 (62%), Positives = 18/24 (75%)
Frame = +2
Query: 563 GFIQKKQAEDMLSKCPPGTFLLRF 634
GF+ K+QA D+L P GTFLLRF
Sbjct: 593 GFVNKQQAHDLLINKPDGTFLLRF 616
>AB208920-1|BAD92157.1| 788|Homo sapiens signal transducer and
activator of transcription 5B variant protein.
Length = 788
Score = 118 bits (283), Expect = 3e-26
Identities = 53/85 (62%), Positives = 68/85 (80%)
Frame = +1
Query: 13 TAQRHFRNMQLRKIKRAEKKGTESVMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIV 192
T HFRNM L++IKR++++G +SV +EK T+LF+SQF+VGG ELVFQV TLSLPVVVIV
Sbjct: 412 TLSAHFRNMSLKRIKRSDRRGAKSVTEEKFTILFESQFSVGGNELVFQVKTLSLPVVVIV 471
Query: 193 HGNQEPHGWATVTWDNAFSPPAGCP 267
HG+Q+ + ATV WDNAF+ P P
Sbjct: 472 HGSQDNNATATVLWDNAFAEPGRVP 496
Score = 103 bits (247), Expect = 7e-22
Identities = 58/148 (39%), Positives = 81/148 (54%), Gaps = 2/148 (1%)
Frame = +3
Query: 252 PGRVPFAVPDKVTWGQLAETLSLKFSS--ATGGSLSEDNLRFLAEKIFRTSLPLNTMELN 425
PGRVPFAVPDKV W QL E L++KF + + L+++NL FLA+K+F S + + +
Sbjct: 492 PGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNNS-SSHLEDYS 550
Query: 426 AMAVSWTQFCKDALPERNFTFWEWFYMVSRSPGTTCGPCGATA**WASYRRSKLRICCPS 605
++VSW+QF ++ LP RN+TFW+WF V P + + +
Sbjct: 551 GLSVSWSQFNRENLPGRNYTFWQWFDGVMEVLKKHLKPHWNDGAILGFVNKQQAHDLLIN 610
Query: 606 VRPGPSCCGSSDSELGGITIAWTGDGNE 689
G SDSE+GGITIAW D E
Sbjct: 611 KPDGTFLLRFSDSEIGGITIAWKFDSQE 638
Score = 46.4 bits (105), Expect = 1e-04
Identities = 20/41 (48%), Positives = 28/41 (68%)
Frame = +2
Query: 512 KVTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
+V + +L+ W D I+GF+ K+QA D+L P GTFLLRF
Sbjct: 580 EVLKKHLKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRF 620
>AB208972-1|BAD92209.1| 765|Homo sapiens signal transducer and
activator of transcription 5A variant protein.
Length = 765
Score = 96.7 bits (230), Expect = 8e-20
Identities = 57/150 (38%), Positives = 80/150 (53%), Gaps = 2/150 (1%)
Frame = +3
Query: 246 QSPGRVPFAVPDKVTWGQLAETLSLKFSS--ATGGSLSEDNLRFLAEKIFRTSLPLNTME 419
Q GRVPFAVPDKV W QL E L++KF + + L+++NL FLA+K+F S + +
Sbjct: 460 QVKGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNNS-SSHLED 518
Query: 420 LNAMAVSWTQFCKDALPERNFTFWEWFYMVSRSPGTTCGPCGATA**WASYRRSKLRICC 599
+ ++VSW+QF ++ LP N+TFW+WF V P + +
Sbjct: 519 YSGLSVSWSQFNRENLPGWNYTFWQWFDGVMEVLKKHHKPHWNDGAILGFVNKQQAHDLL 578
Query: 600 PSVRPGPSCCGSSDSELGGITIAWTGDGNE 689
+ G SDSE+GGITIAW D E
Sbjct: 579 INKPDGTFLLRFSDSEIGGITIAWKFDSPE 608
Score = 71.3 bits (167), Expect = 3e-12
Identities = 31/49 (63%), Positives = 40/49 (81%)
Frame = +1
Query: 13 TAQRHFRNMQLRKIKRAEKKGTESVMDEKLTLLFQSQFNVGGGELVFQV 159
T HFRNM L++IKRA+++G ESV +EK T+LF+SQF+VG ELVFQV
Sbjct: 413 TLSAHFRNMSLKRIKRADRRGAESVTEEKFTVLFESQFSVGSNELVFQV 461
Score = 43.6 bits (98), Expect = 8e-04
Identities = 19/41 (46%), Positives = 27/41 (65%)
Frame = +2
Query: 512 KVTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
+V + + + W D I+GF+ K+QA D+L P GTFLLRF
Sbjct: 550 EVLKKHHKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRF 590
>U16031-1|AAA57193.1| 847|Homo sapiens IL-4 Stat protein.
Length = 847
Score = 95.9 bits (228), Expect = 1e-19
Identities = 43/74 (58%), Positives = 57/74 (77%)
Frame = +1
Query: 28 FRNMQLRKIKRAEKKGTESVMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIVHGNQE 207
F+N+ L+KIKR E+KGTESV +EK +LF + F +G G+L Q+ LSLP+VVIVHGNQ+
Sbjct: 360 FKNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQD 419
Query: 208 PHGWATVTWDNAFS 249
+ AT+ WDNAFS
Sbjct: 420 NNAKATILWDNAFS 433
Score = 72.5 bits (170), Expect = 2e-12
Identities = 36/83 (43%), Positives = 52/83 (62%), Gaps = 2/83 (2%)
Frame = +3
Query: 258 RVPFAVPDKVTWGQLAETLSLKFSSATGGS--LSEDNLRFLAEKIFRTSLPLNTMELNAM 431
RVPF V ++V W ++ ETL+LKF + G + L ++ FLA+KIF + L+
Sbjct: 437 RVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQKIFNDN-SLSMEAFQHR 495
Query: 432 AVSWTQFCKDALPERNFTFWEWF 500
+VSW+QF K+ L R FTFW+WF
Sbjct: 496 SVSWSQFNKEILLGRGFTFWQWF 518
Score = 46.4 bits (105), Expect = 1e-04
Identities = 21/40 (52%), Positives = 27/40 (67%)
Frame = +2
Query: 515 VTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
+T+ LR+ W DRLI+GFI K+ +L P GTFLLRF
Sbjct: 524 LTKRCLRSYWSDRLIIGFISKQYVTSLLLNEPDGTFLLRF 563
>BC075852-1|AAH75852.1| 847|Homo sapiens signal transducer and
activator of transcription 6, interleukin-4 induced
protein.
Length = 847
Score = 95.9 bits (228), Expect = 1e-19
Identities = 43/74 (58%), Positives = 57/74 (77%)
Frame = +1
Query: 28 FRNMQLRKIKRAEKKGTESVMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIVHGNQE 207
F+N+ L+KIKR E+KGTESV +EK +LF + F +G G+L Q+ LSLP+VVIVHGNQ+
Sbjct: 360 FKNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQD 419
Query: 208 PHGWATVTWDNAFS 249
+ AT+ WDNAFS
Sbjct: 420 NNAKATILWDNAFS 433
Score = 72.5 bits (170), Expect = 2e-12
Identities = 36/83 (43%), Positives = 52/83 (62%), Gaps = 2/83 (2%)
Frame = +3
Query: 258 RVPFAVPDKVTWGQLAETLSLKFSSATGGS--LSEDNLRFLAEKIFRTSLPLNTMELNAM 431
RVPF V ++V W ++ ETL+LKF + G + L ++ FLA+KIF + L+
Sbjct: 437 RVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQKIFNDN-SLSMEAFQHR 495
Query: 432 AVSWTQFCKDALPERNFTFWEWF 500
+VSW+QF K+ L R FTFW+WF
Sbjct: 496 SVSWSQFNKEILLGRGFTFWQWF 518
Score = 46.4 bits (105), Expect = 1e-04
Identities = 21/40 (52%), Positives = 27/40 (67%)
Frame = +2
Query: 515 VTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
+T+ LR+ W DRLI+GFI K+ +L P GTFLLRF
Sbjct: 524 LTKRCLRSYWSDRLIIGFISKQYVTSLLLNEPDGTFLLRF 563
>AF417842-1|AAL06595.1| 847|Homo sapiens signal transducer and
activator of transcription 6, interleukin-4 induced
protein.
Length = 847
Score = 95.9 bits (228), Expect = 1e-19
Identities = 43/74 (58%), Positives = 57/74 (77%)
Frame = +1
Query: 28 FRNMQLRKIKRAEKKGTESVMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIVHGNQE 207
F+N+ L+KIKR E+KGTESV +EK +LF + F +G G+L Q+ LSLP+VVIVHGNQ+
Sbjct: 360 FKNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQD 419
Query: 208 PHGWATVTWDNAFS 249
+ AT+ WDNAFS
Sbjct: 420 NNAKATILWDNAFS 433
Score = 72.5 bits (170), Expect = 2e-12
Identities = 36/83 (43%), Positives = 52/83 (62%), Gaps = 2/83 (2%)
Frame = +3
Query: 258 RVPFAVPDKVTWGQLAETLSLKFSSATGGS--LSEDNLRFLAEKIFRTSLPLNTMELNAM 431
RVPF V ++V W ++ ETL+LKF + G + L ++ FLA+KIF + L+
Sbjct: 437 RVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQKIFNDN-SLSMEAFQHR 495
Query: 432 AVSWTQFCKDALPERNFTFWEWF 500
+VSW+QF K+ L R FTFW+WF
Sbjct: 496 SVSWSQFNKEILLGRGFTFWQWF 518
Score = 46.4 bits (105), Expect = 1e-04
Identities = 21/40 (52%), Positives = 27/40 (67%)
Frame = +2
Query: 515 VTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
+T+ LR+ W DRLI+GFI K+ +L P GTFLLRF
Sbjct: 524 LTKRCLRSYWSDRLIIGFISKQYVTSLLLNEPDGTFLLRF 563
>AF067575-1|AAC67525.1| 847|Homo sapiens signal transducer and
activator of transcription 6 protein.
Length = 847
Score = 95.9 bits (228), Expect = 1e-19
Identities = 43/74 (58%), Positives = 57/74 (77%)
Frame = +1
Query: 28 FRNMQLRKIKRAEKKGTESVMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIVHGNQE 207
F+N+ L+KIKR E+KGTESV +EK +LF + F +G G+L Q+ LSLP+VVIVHGNQ+
Sbjct: 360 FKNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQD 419
Query: 208 PHGWATVTWDNAFS 249
+ AT+ WDNAFS
Sbjct: 420 NNAKATILWDNAFS 433
Score = 72.5 bits (170), Expect = 2e-12
Identities = 36/83 (43%), Positives = 52/83 (62%), Gaps = 2/83 (2%)
Frame = +3
Query: 258 RVPFAVPDKVTWGQLAETLSLKFSSATGGS--LSEDNLRFLAEKIFRTSLPLNTMELNAM 431
RVPF V ++V W ++ ETL+LKF + G + L ++ FLA+KIF + L+
Sbjct: 437 RVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQKIFNDN-SLSMEAFQHR 495
Query: 432 AVSWTQFCKDALPERNFTFWEWF 500
+VSW+QF K+ L R FTFW+WF
Sbjct: 496 SVSWSQFNKEILLGRGFTFWQWF 518
Score = 46.4 bits (105), Expect = 1e-04
Identities = 21/40 (52%), Positives = 27/40 (67%)
Frame = +2
Query: 515 VTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
+T+ LR+ W DRLI+GFI K+ +L P GTFLLRF
Sbjct: 524 LTKRCLRSYWSDRLIIGFISKQYVTSLLLNEPDGTFLLRF 563
>AB103089-1|BAD89432.1| 673|Homo sapiens signal transducer and
activator of transcription 6 nirs variant 2 protein.
Length = 673
Score = 95.9 bits (228), Expect = 1e-19
Identities = 43/74 (58%), Positives = 57/74 (77%)
Frame = +1
Query: 28 FRNMQLRKIKRAEKKGTESVMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIVHGNQE 207
F+N+ L+KIKR E+KGTESV +EK +LF + F +G G+L Q+ LSLP+VVIVHGNQ+
Sbjct: 186 FKNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQD 245
Query: 208 PHGWATVTWDNAFS 249
+ AT+ WDNAFS
Sbjct: 246 NNAKATILWDNAFS 259
Score = 72.5 bits (170), Expect = 2e-12
Identities = 36/83 (43%), Positives = 52/83 (62%), Gaps = 2/83 (2%)
Frame = +3
Query: 258 RVPFAVPDKVTWGQLAETLSLKFSSATGGS--LSEDNLRFLAEKIFRTSLPLNTMELNAM 431
RVPF V ++V W ++ ETL+LKF + G + L ++ FLA+KIF + L+
Sbjct: 263 RVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQKIFNDN-SLSMEAFQHR 321
Query: 432 AVSWTQFCKDALPERNFTFWEWF 500
+VSW+QF K+ L R FTFW+WF
Sbjct: 322 SVSWSQFNKEILLGRGFTFWQWF 344
Score = 46.4 bits (105), Expect = 1e-04
Identities = 21/40 (52%), Positives = 27/40 (67%)
Frame = +2
Query: 515 VTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
+T+ LR+ W DRLI+GFI K+ +L P GTFLLRF
Sbjct: 350 LTKRCLRSYWSDRLIIGFISKQYVTSLLLNEPDGTFLLRF 389
>BT007380-1|AAP36044.1| 679|Homo sapiens signal transducer and
activator of transcription 6, interleukin-4 induced
protein.
Length = 679
Score = 92.3 bits (219), Expect = 2e-18
Identities = 42/74 (56%), Positives = 56/74 (75%)
Frame = +1
Query: 28 FRNMQLRKIKRAEKKGTESVMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIVHGNQE 207
F+N+ L+KIKR E+KGTESV +EK +LF + F +G G+L Q+ LSLP+VVIVHGNQ+
Sbjct: 360 FKNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQD 419
Query: 208 PHGWATVTWDNAFS 249
+ AT+ W NAFS
Sbjct: 420 NNAKATILWYNAFS 433
Score = 72.5 bits (170), Expect = 2e-12
Identities = 36/83 (43%), Positives = 52/83 (62%), Gaps = 2/83 (2%)
Frame = +3
Query: 258 RVPFAVPDKVTWGQLAETLSLKFSSATGGS--LSEDNLRFLAEKIFRTSLPLNTMELNAM 431
RVPF V ++V W ++ ETL+LKF + G + L ++ FLA+KIF + L+
Sbjct: 437 RVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQKIFNDN-SLSMEAFQHR 495
Query: 432 AVSWTQFCKDALPERNFTFWEWF 500
+VSW+QF K+ L R FTFW+WF
Sbjct: 496 SVSWSQFNKEILLGRGFTFWQWF 518
Score = 46.4 bits (105), Expect = 1e-04
Identities = 21/40 (52%), Positives = 27/40 (67%)
Frame = +2
Query: 515 VTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
+T+ LR+ W DRLI+GFI K+ +L P GTFLLRF
Sbjct: 524 LTKRCLRSYWSDRLIIGFISKQYVTSLLLNEPDGTFLLRF 563
>L78440-1|AAB05605.1| 748|Homo sapiens signal transducer and
activator of transcription 4 protein.
Length = 748
Score = 70.5 bits (165), Expect = 6e-12
Identities = 49/159 (30%), Positives = 66/159 (41%)
Frame = +3
Query: 249 SPGRVPFAVPDKVTWGQLAETLSLKFSSATGGSLSEDNLRFLAEKIFRTSLPLNTMELNA 428
S V F P T QL E +S +FSS G L+ D L LAEK+ S +
Sbjct: 477 SQNLVFFNNPPPATLSQLLEVMSWQFSSYVGRGLNSDQLHMLAEKLTVQS------SYSD 530
Query: 429 MAVSWTQFCKDALPERNFTFWEWFYMVSRSPGTTCGPCGATA**WASYRRSKLRICCPSV 608
++W +FCK+ LP ++FTFW W + P + K R+
Sbjct: 531 GHLTWAKFCKEHLPGKSFTFWTWLEAILDLIKKHILPLWIDGYVMGFVSKEKERLLLKDK 590
Query: 609 RPGPSCCGSSDSELGGITIAWTGDGNEVFSCSLHVARPH 725
PG S+S LGGIT W D +E H P+
Sbjct: 591 MPGTFLLRFSESHLGGITFTWV-DHSESGEVRFHSVEPY 628
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/75 (36%), Positives = 45/75 (60%), Gaps = 4/75 (5%)
Frame = +1
Query: 28 FRNMQLRKIKR-AEKKGTES---VMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIVH 195
FR++Q +++K A KG E V +E ++ F++Q + G L + T SLPVV+I +
Sbjct: 399 FRHLQPKEMKSSAGGKGNEGCHMVTEELHSITFETQICLYG--LTIDLETSSLPVVMISN 456
Query: 196 GNQEPHGWATVTWDN 240
+Q P+ WA++ W N
Sbjct: 457 VSQLPNAWASIIWYN 471
Score = 39.1 bits (87), Expect = 0.017
Identities = 16/38 (42%), Positives = 24/38 (63%)
Frame = +2
Query: 521 RDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
+ ++ LW D +MGF+ K++ +L PGTFLLRF
Sbjct: 562 KKHILPLWIDGYVMGFVSKEKERLLLKDKMPGTFLLRF 599
>BC031212-1|AAH31212.1| 748|Homo sapiens STAT4 protein protein.
Length = 748
Score = 70.5 bits (165), Expect = 6e-12
Identities = 49/159 (30%), Positives = 66/159 (41%)
Frame = +3
Query: 249 SPGRVPFAVPDKVTWGQLAETLSLKFSSATGGSLSEDNLRFLAEKIFRTSLPLNTMELNA 428
S V F P T QL E +S +FSS G L+ D L LAEK+ S +
Sbjct: 477 SQNLVFFNNPPPATLSQLLEVMSWQFSSYVGRGLNSDQLHMLAEKLTVQS------SYSD 530
Query: 429 MAVSWTQFCKDALPERNFTFWEWFYMVSRSPGTTCGPCGATA**WASYRRSKLRICCPSV 608
++W +FCK+ LP ++FTFW W + P + K R+
Sbjct: 531 GHLTWAKFCKEHLPGKSFTFWTWLEAILDLIKKHILPLWIDGYVMGFVSKEKERLLLKDK 590
Query: 609 RPGPSCCGSSDSELGGITIAWTGDGNEVFSCSLHVARPH 725
PG S+S LGGIT W D +E H P+
Sbjct: 591 MPGTFLLRFSESHLGGITFTWV-DHSESGEVRFHSVEPY 628
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/75 (36%), Positives = 45/75 (60%), Gaps = 4/75 (5%)
Frame = +1
Query: 28 FRNMQLRKIKR-AEKKGTES---VMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIVH 195
FR++Q +++K A KG E V +E ++ F++Q + G L + T SLPVV+I +
Sbjct: 399 FRHLQPKEMKSSAGGKGNEGCHMVTEELHSITFETQICLYG--LTIDLETSSLPVVMISN 456
Query: 196 GNQEPHGWATVTWDN 240
+Q P+ WA++ W N
Sbjct: 457 VSQLPNAWASIIWYN 471
Score = 39.1 bits (87), Expect = 0.017
Identities = 16/38 (42%), Positives = 24/38 (63%)
Frame = +2
Query: 521 RDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
+ ++ LW D +MGF+ K++ +L PGTFLLRF
Sbjct: 562 KKHILPLWIDGYVMGFVSKEKERLLLKDKMPGTFLLRF 599
>AF423072-1|AAL12164.1| 652|Homo sapiens signal transducer and
activator of transcription 4 protein.
Length = 652
Score = 70.5 bits (165), Expect = 6e-12
Identities = 49/159 (30%), Positives = 66/159 (41%)
Frame = +3
Query: 249 SPGRVPFAVPDKVTWGQLAETLSLKFSSATGGSLSEDNLRFLAEKIFRTSLPLNTMELNA 428
S V F P T QL E +S +FSS G L+ D L LAEK+ S +
Sbjct: 381 SQNLVFFNNPPPATLSQLLEVMSWQFSSYVGRGLNSDQLHMLAEKLTVQS------SYSD 434
Query: 429 MAVSWTQFCKDALPERNFTFWEWFYMVSRSPGTTCGPCGATA**WASYRRSKLRICCPSV 608
++W +FCK+ LP ++FTFW W + P + K R+
Sbjct: 435 GHLTWAKFCKEHLPGKSFTFWTWLEAILDLIKKHILPLWIDGYVMGFVSKEKERLLLKDK 494
Query: 609 RPGPSCCGSSDSELGGITIAWTGDGNEVFSCSLHVARPH 725
PG S+S LGGIT W D +E H P+
Sbjct: 495 MPGTFLLRFSESHLGGITFTWV-DHSESGEVRFHSVEPY 532
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/75 (36%), Positives = 45/75 (60%), Gaps = 4/75 (5%)
Frame = +1
Query: 28 FRNMQLRKIKR-AEKKGTES---VMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIVH 195
FR++Q +++K A KG E V +E ++ F++Q + G L + T SLPVV+I +
Sbjct: 303 FRHLQPKEMKSSAGGKGNEGCHMVTEELHSITFETQICLYG--LTIDLETSSLPVVMISN 360
Query: 196 GNQEPHGWATVTWDN 240
+Q P+ WA++ W N
Sbjct: 361 VSQLPNAWASIIWYN 375
Score = 39.1 bits (87), Expect = 0.017
Identities = 16/38 (42%), Positives = 24/38 (63%)
Frame = +2
Query: 521 RDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
+ ++ LW D +MGF+ K++ +L PGTFLLRF
Sbjct: 466 KKHILPLWIDGYVMGFVSKEKERLLLKDKMPGTFLLRF 503
>AC067945-3|AAY24184.1| 657|Homo sapiens unknown protein.
Length = 657
Score = 70.5 bits (165), Expect = 6e-12
Identities = 49/159 (30%), Positives = 66/159 (41%)
Frame = +3
Query: 249 SPGRVPFAVPDKVTWGQLAETLSLKFSSATGGSLSEDNLRFLAEKIFRTSLPLNTMELNA 428
S V F P T QL E +S +FSS G L+ D L LAEK+ S +
Sbjct: 386 SQNLVFFNNPPPATLSQLLEVMSWQFSSYVGRGLNSDQLHMLAEKLTVQS------SYSD 439
Query: 429 MAVSWTQFCKDALPERNFTFWEWFYMVSRSPGTTCGPCGATA**WASYRRSKLRICCPSV 608
++W +FCK+ LP ++FTFW W + P + K R+
Sbjct: 440 GHLTWAKFCKEHLPGKSFTFWTWLEAILDLIKKHILPLWIDGYVMGFVSKEKERLLLKDK 499
Query: 609 RPGPSCCGSSDSELGGITIAWTGDGNEVFSCSLHVARPH 725
PG S+S LGGIT W D +E H P+
Sbjct: 500 MPGTFLLRFSESHLGGITFTWV-DHSESGEVRFHSVEPY 537
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/75 (36%), Positives = 45/75 (60%), Gaps = 4/75 (5%)
Frame = +1
Query: 28 FRNMQLRKIKR-AEKKGTES---VMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIVH 195
FR++Q +++K A KG E V +E ++ F++Q + G L + T SLPVV+I +
Sbjct: 308 FRHLQPKEMKSSAGGKGNEGCHMVTEELHSITFETQICLYG--LTIDLETSSLPVVMISN 365
Query: 196 GNQEPHGWATVTWDN 240
+Q P+ WA++ W N
Sbjct: 366 VSQLPNAWASIIWYN 380
Score = 39.1 bits (87), Expect = 0.017
Identities = 16/38 (42%), Positives = 24/38 (63%)
Frame = +2
Query: 521 RDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
+ ++ LW D +MGF+ K++ +L PGTFLLRF
Sbjct: 471 KKHILPLWIDGYVMGFVSKEKERLLLKDKMPGTFLLRF 508
>AB209043-1|BAD92280.1| 332|Homo sapiens signal transducer and
activator of transcription 4 variant protein.
Length = 332
Score = 70.5 bits (165), Expect = 6e-12
Identities = 49/159 (30%), Positives = 66/159 (41%)
Frame = +3
Query: 249 SPGRVPFAVPDKVTWGQLAETLSLKFSSATGGSLSEDNLRFLAEKIFRTSLPLNTMELNA 428
S V F P T QL E +S +FSS G L+ D L LAEK+ S +
Sbjct: 127 SQNLVFFNNPPPATLSQLLEVMSWQFSSYVGRGLNSDQLHMLAEKLTVQS------SYSD 180
Query: 429 MAVSWTQFCKDALPERNFTFWEWFYMVSRSPGTTCGPCGATA**WASYRRSKLRICCPSV 608
++W +FCK+ LP ++FTFW W + P + K R+
Sbjct: 181 GHLTWAKFCKEHLPGKSFTFWTWLEAILDLIKKHILPLWIDGYVMGFVSKEKERLLLKDK 240
Query: 609 RPGPSCCGSSDSELGGITIAWTGDGNEVFSCSLHVARPH 725
PG S+S LGGIT W D +E H P+
Sbjct: 241 MPGTFLLRFSESHLGGITFTWV-DHSESGEVRFHSVEPY 278
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/75 (36%), Positives = 45/75 (60%), Gaps = 4/75 (5%)
Frame = +1
Query: 28 FRNMQLRKIKR-AEKKGTES---VMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIVH 195
FR++Q +++K A KG E V +E ++ F++Q + G L + T SLPVV+I +
Sbjct: 49 FRHLQPKEMKSSAGGKGNEGCHMVTEELHSITFETQICLYG--LTIDLETSSLPVVMISN 106
Query: 196 GNQEPHGWATVTWDN 240
+Q P+ WA++ W N
Sbjct: 107 VSQLPNAWASIIWYN 121
Score = 39.1 bits (87), Expect = 0.017
Identities = 16/38 (42%), Positives = 24/38 (63%)
Frame = +2
Query: 521 RDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
+ ++ LW D +MGF+ K++ +L PGTFLLRF
Sbjct: 212 KKHILPLWIDGYVMGFVSKEKERLLLKDKMPGTFLLRF 249
>M97935-1|AAB64012.1| 750|Homo sapiens transcription factor ISGF-3
protein.
Length = 750
Score = 60.1 bits (139), Expect = 9e-09
Identities = 40/154 (25%), Positives = 59/154 (38%), Gaps = 1/154 (0%)
Frame = +3
Query: 267 FAVPDKVTWGQLAETLSLKFSSATGGSLSEDNLRFLAEKIFRTSLPLNTMELNAMAVSWT 446
F P W QL+E LS +FSS T L+ D L L EK+ + + + + WT
Sbjct: 487 FLTPPCARWAQLSEVLSWQFSSVTKRGLNVDQLNMLGEKLLGPNASPDGL------IPWT 540
Query: 447 QFCKDALPERNFTFWEWFYMVSRSPGTTCGPCGATA**WASYRRSKLRICCPSVRPGPSC 626
+FCK+ + ++NF FW W + P + + R +PG
Sbjct: 541 RFCKENINDKNFPFWLWIESILELIKKHLLPLWNDGCIMGFISKERERALLKDQQPGTFL 600
Query: 627 CGSSDSEL-GGITIAWTGDGNEVFSCSLHVARPH 725
S+S G IT W H P+
Sbjct: 601 LRFSESSREGAITFTWVERSQNGGEPDFHAVEPY 634
Score = 48.8 bits (111), Expect = 2e-05
Identities = 30/74 (40%), Positives = 44/74 (59%), Gaps = 3/74 (4%)
Frame = +1
Query: 28 FRNMQLRKIKRAEKKGTES---VMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIVHG 198
FR++QL++ K A + E V +E +L F++Q G LV + T SLPVVVI +
Sbjct: 404 FRHLQLKEQKNAGTRTNEGPLIVTEELHSLSFETQLCQPG--LVIDLETTSLPVVVISNV 461
Query: 199 NQEPHGWATVTWDN 240
+Q P GWA++ W N
Sbjct: 462 SQLPSGWASILWYN 475
Score = 41.5 bits (93), Expect = 0.003
Identities = 19/41 (46%), Positives = 26/41 (63%)
Frame = +2
Query: 512 KVTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
++ + +L LW D IMGFI K++ +L PGTFLLRF
Sbjct: 563 ELIKKHLLPLWNDGCIMGFISKERERALLKDQQPGTFLLRF 603
>BT007241-1|AAP35905.1| 712|Homo sapiens signal transducer and
activator of transcription 1, 91kDa protein.
Length = 712
Score = 60.1 bits (139), Expect = 9e-09
Identities = 40/154 (25%), Positives = 59/154 (38%), Gaps = 1/154 (0%)
Frame = +3
Query: 267 FAVPDKVTWGQLAETLSLKFSSATGGSLSEDNLRFLAEKIFRTSLPLNTMELNAMAVSWT 446
F P W QL+E LS +FSS T L+ D L L EK+ + + + + WT
Sbjct: 487 FLTPPCARWAQLSEVLSWQFSSVTKRGLNVDQLNMLGEKLLGPNASPDGL------IPWT 540
Query: 447 QFCKDALPERNFTFWEWFYMVSRSPGTTCGPCGATA**WASYRRSKLRICCPSVRPGPSC 626
+FCK+ + ++NF FW W + P + + R +PG
Sbjct: 541 RFCKENINDKNFPFWLWIESILELIKKHLLPLWNDGCIMGFISKERERALLKDQQPGTFL 600
Query: 627 CGSSDSEL-GGITIAWTGDGNEVFSCSLHVARPH 725
S+S G IT W H P+
Sbjct: 601 LRFSESSREGAITFTWVERSQNGGEPDFHAVEPY 634
Score = 48.8 bits (111), Expect = 2e-05
Identities = 30/74 (40%), Positives = 44/74 (59%), Gaps = 3/74 (4%)
Frame = +1
Query: 28 FRNMQLRKIKRAEKKGTES---VMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIVHG 198
FR++QL++ K A + E V +E +L F++Q G LV + T SLPVVVI +
Sbjct: 404 FRHLQLKEQKNAGTRTNEGPLIVTEELHSLSFETQLCQPG--LVIDLETTSLPVVVISNV 461
Query: 199 NQEPHGWATVTWDN 240
+Q P GWA++ W N
Sbjct: 462 SQLPSGWASILWYN 475
Score = 41.5 bits (93), Expect = 0.003
Identities = 19/41 (46%), Positives = 26/41 (63%)
Frame = +2
Query: 512 KVTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
++ + +L LW D IMGFI K++ +L PGTFLLRF
Sbjct: 563 ELIKKHLLPLWNDGCIMGFISKERERALLKDQQPGTFLLRF 603
>BC002704-1|AAH02704.1| 712|Homo sapiens signal transducer and
activator of transcription 1, 91kDa protein.
Length = 712
Score = 60.1 bits (139), Expect = 9e-09
Identities = 40/154 (25%), Positives = 59/154 (38%), Gaps = 1/154 (0%)
Frame = +3
Query: 267 FAVPDKVTWGQLAETLSLKFSSATGGSLSEDNLRFLAEKIFRTSLPLNTMELNAMAVSWT 446
F P W QL+E LS +FSS T L+ D L L EK+ + + + + WT
Sbjct: 487 FLTPPCARWAQLSEVLSWQFSSVTKRGLNVDQLNMLGEKLLGPNASPDGL------IPWT 540
Query: 447 QFCKDALPERNFTFWEWFYMVSRSPGTTCGPCGATA**WASYRRSKLRICCPSVRPGPSC 626
+FCK+ + ++NF FW W + P + + R +PG
Sbjct: 541 RFCKENINDKNFPFWLWIESILELIKKHLLPLWNDGCIMGFISKERERALLKDQQPGTFL 600
Query: 627 CGSSDSEL-GGITIAWTGDGNEVFSCSLHVARPH 725
S+S G IT W H P+
Sbjct: 601 LRFSESSREGAITFTWVERSQNGGEPDFHAVEPY 634
Score = 48.8 bits (111), Expect = 2e-05
Identities = 30/74 (40%), Positives = 44/74 (59%), Gaps = 3/74 (4%)
Frame = +1
Query: 28 FRNMQLRKIKRAEKKGTES---VMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIVHG 198
FR++QL++ K A + E V +E +L F++Q G LV + T SLPVVVI +
Sbjct: 404 FRHLQLKEQKNAGTRTNEGPLIVTEELHSLSFETQLCQPG--LVIDLETTSLPVVVISNV 461
Query: 199 NQEPHGWATVTWDN 240
+Q P GWA++ W N
Sbjct: 462 SQLPSGWASILWYN 475
Score = 41.5 bits (93), Expect = 0.003
Identities = 19/41 (46%), Positives = 26/41 (63%)
Frame = +2
Query: 512 KVTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
++ + +L LW D IMGFI K++ +L PGTFLLRF
Sbjct: 563 ELIKKHLLPLWNDGCIMGFISKERERALLKDQQPGTFLLRF 603
>AY865620-1|AAW56072.1| 750|Homo sapiens signal transducer and
activator of transcription 1, 91kDa protein.
Length = 750
Score = 60.1 bits (139), Expect = 9e-09
Identities = 40/154 (25%), Positives = 59/154 (38%), Gaps = 1/154 (0%)
Frame = +3
Query: 267 FAVPDKVTWGQLAETLSLKFSSATGGSLSEDNLRFLAEKIFRTSLPLNTMELNAMAVSWT 446
F P W QL+E LS +FSS T L+ D L L EK+ + + + + WT
Sbjct: 487 FLTPPCARWAQLSEVLSWQFSSVTKRGLNVDQLNMLGEKLLGPNASPDGL------IPWT 540
Query: 447 QFCKDALPERNFTFWEWFYMVSRSPGTTCGPCGATA**WASYRRSKLRICCPSVRPGPSC 626
+FCK+ + ++NF FW W + P + + R +PG
Sbjct: 541 RFCKENINDKNFPFWLWIESILELIKKHLLPLWNDGCIMGFISKERERALLKDQQPGTFL 600
Query: 627 CGSSDSEL-GGITIAWTGDGNEVFSCSLHVARPH 725
S+S G IT W H P+
Sbjct: 601 LRFSESSREGAITFTWVERSQNGGEPDFHAVEPY 634
Score = 48.8 bits (111), Expect = 2e-05
Identities = 30/74 (40%), Positives = 44/74 (59%), Gaps = 3/74 (4%)
Frame = +1
Query: 28 FRNMQLRKIKRAEKKGTES---VMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIVHG 198
FR++QL++ K A + E V +E +L F++Q G LV + T SLPVVVI +
Sbjct: 404 FRHLQLKEQKNAGTRTNEGPLIVTEELHSLSFETQLCQPG--LVIDLETTSLPVVVISNV 461
Query: 199 NQEPHGWATVTWDN 240
+Q P GWA++ W N
Sbjct: 462 SQLPSGWASILWYN 475
Score = 41.5 bits (93), Expect = 0.003
Identities = 19/41 (46%), Positives = 26/41 (63%)
Frame = +2
Query: 512 KVTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
++ + +L LW D IMGFI K++ +L PGTFLLRF
Sbjct: 563 ELIKKHLLPLWNDGCIMGFISKERERALLKDQQPGTFLLRF 603
>AC067945-2|AAY24183.1| 750|Homo sapiens unknown protein.
Length = 750
Score = 60.1 bits (139), Expect = 9e-09
Identities = 40/154 (25%), Positives = 59/154 (38%), Gaps = 1/154 (0%)
Frame = +3
Query: 267 FAVPDKVTWGQLAETLSLKFSSATGGSLSEDNLRFLAEKIFRTSLPLNTMELNAMAVSWT 446
F P W QL+E LS +FSS T L+ D L L EK+ + + + + WT
Sbjct: 487 FLTPPCARWAQLSEVLSWQFSSVTKRGLNVDQLNMLGEKLLGPNASPDGL------IPWT 540
Query: 447 QFCKDALPERNFTFWEWFYMVSRSPGTTCGPCGATA**WASYRRSKLRICCPSVRPGPSC 626
+FCK+ + ++NF FW W + P + + R +PG
Sbjct: 541 RFCKENINDKNFPFWLWIESILELIKKHLLPLWNDGCIMGFISKERERALLKDQQPGTFL 600
Query: 627 CGSSDSEL-GGITIAWTGDGNEVFSCSLHVARPH 725
S+S G IT W H P+
Sbjct: 601 LRFSESSREGAITFTWVERSQNGGEPDFHAVEPY 634
Score = 48.8 bits (111), Expect = 2e-05
Identities = 30/74 (40%), Positives = 44/74 (59%), Gaps = 3/74 (4%)
Frame = +1
Query: 28 FRNMQLRKIKRAEKKGTES---VMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIVHG 198
FR++QL++ K A + E V +E +L F++Q G LV + T SLPVVVI +
Sbjct: 404 FRHLQLKEQKNAGTRTNEGPLIVTEELHSLSFETQLCQPG--LVIDLETTSLPVVVISNV 461
Query: 199 NQEPHGWATVTWDN 240
+Q P GWA++ W N
Sbjct: 462 SQLPSGWASILWYN 475
Score = 41.5 bits (93), Expect = 0.003
Identities = 19/41 (46%), Positives = 26/41 (63%)
Frame = +2
Query: 512 KVTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
++ + +L LW D IMGFI K++ +L PGTFLLRF
Sbjct: 563 ELIKKHLLPLWNDGCIMGFISKERERALLKDQQPGTFLLRF 603
>BC014482-1|AAH14482.1| 770|Homo sapiens signal transducer and
activator of transcription 3 (acute-phase response
factor protein.
Length = 770
Score = 56.8 bits (131), Expect = 8e-08
Identities = 28/77 (36%), Positives = 41/77 (53%)
Frame = +3
Query: 267 FAVPDKVTWGQLAETLSLKFSSATGGSLSEDNLRFLAEKIFRTSLPLNTMELNAMAVSWT 446
F P TW Q+AE LS +FSS T LS + L LAEK+ + + ++W
Sbjct: 493 FTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPG-----VNYSGCQITWA 547
Query: 447 QFCKDALPERNFTFWEW 497
+FCK+ + + F+FW W
Sbjct: 548 KFCKENMAGKGFSFWVW 564
Score = 46.0 bits (104), Expect = 2e-04
Identities = 20/40 (50%), Positives = 27/40 (67%)
Frame = +2
Query: 515 VTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
+ + Y+ LW + IMGFI K++ +LS PPGTFLLRF
Sbjct: 571 LVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRF 610
Score = 32.3 bits (70), Expect = 2.0
Identities = 20/53 (37%), Positives = 32/53 (60%), Gaps = 1/53 (1%)
Frame = +1
Query: 85 VMDEKLTLL-FQSQFNVGGGELVFQVWTLSLPVVVIVHGNQEPHGWATVTWDN 240
++ E+L L+ F+++ G L + T SLPVVVI + Q P+ WA++ W N
Sbjct: 431 IVTEELHLITFETEVYHQG--LKIDLETHSLPVVVISNICQMPNAWASILWYN 481
>BC000627-1|AAH00627.1| 769|Homo sapiens signal transducer and
activator of transcription 3 (acute-phase response
factor protein.
Length = 769
Score = 56.8 bits (131), Expect = 8e-08
Identities = 28/77 (36%), Positives = 41/77 (53%)
Frame = +3
Query: 267 FAVPDKVTWGQLAETLSLKFSSATGGSLSEDNLRFLAEKIFRTSLPLNTMELNAMAVSWT 446
F P TW Q+AE LS +FSS T LS + L LAEK+ + + ++W
Sbjct: 493 FTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPG-----VNYSGCQITWA 547
Query: 447 QFCKDALPERNFTFWEW 497
+FCK+ + + F+FW W
Sbjct: 548 KFCKENMAGKGFSFWVW 564
Score = 46.0 bits (104), Expect = 2e-04
Identities = 20/40 (50%), Positives = 27/40 (67%)
Frame = +2
Query: 515 VTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
+ + Y+ LW + IMGFI K++ +LS PPGTFLLRF
Sbjct: 571 LVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRF 610
Score = 32.3 bits (70), Expect = 2.0
Identities = 20/53 (37%), Positives = 32/53 (60%), Gaps = 1/53 (1%)
Frame = +1
Query: 85 VMDEKLTLL-FQSQFNVGGGELVFQVWTLSLPVVVIVHGNQEPHGWATVTWDN 240
++ E+L L+ F+++ G L + T SLPVVVI + Q P+ WA++ W N
Sbjct: 431 IVTEELHLITFETEVYHQG--LKIDLETHSLPVVVISNICQMPNAWASILWYN 481
>AY572796-1|AAS66986.1| 769|Homo sapiens signal transducer and
activator of transcription 3 (acute-phase response
factor protein.
Length = 769
Score = 56.8 bits (131), Expect = 8e-08
Identities = 28/77 (36%), Positives = 41/77 (53%)
Frame = +3
Query: 267 FAVPDKVTWGQLAETLSLKFSSATGGSLSEDNLRFLAEKIFRTSLPLNTMELNAMAVSWT 446
F P TW Q+AE LS +FSS T LS + L LAEK+ + + ++W
Sbjct: 493 FTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPG-----VNYSGCQITWA 547
Query: 447 QFCKDALPERNFTFWEW 497
+FCK+ + + F+FW W
Sbjct: 548 KFCKENMAGKGFSFWVW 564
Score = 46.0 bits (104), Expect = 2e-04
Identities = 20/40 (50%), Positives = 27/40 (67%)
Frame = +2
Query: 515 VTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
+ + Y+ LW + IMGFI K++ +LS PPGTFLLRF
Sbjct: 571 LVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRF 610
Score = 32.3 bits (70), Expect = 2.0
Identities = 20/53 (37%), Positives = 32/53 (60%), Gaps = 1/53 (1%)
Frame = +1
Query: 85 VMDEKLTLL-FQSQFNVGGGELVFQVWTLSLPVVVIVHGNQEPHGWATVTWDN 240
++ E+L L+ F+++ G L + T SLPVVVI + Q P+ WA++ W N
Sbjct: 431 IVTEELHLITFETEVYHQG--LKIDLETHSLPVVVISNICQMPNAWASILWYN 481
>AJ012463-1|CAA10032.1| 770|Homo sapiens transcription factor
protein.
Length = 770
Score = 56.8 bits (131), Expect = 8e-08
Identities = 28/77 (36%), Positives = 41/77 (53%)
Frame = +3
Query: 267 FAVPDKVTWGQLAETLSLKFSSATGGSLSEDNLRFLAEKIFRTSLPLNTMELNAMAVSWT 446
F P TW Q+AE LS +FSS T LS + L LAEK+ + + ++W
Sbjct: 493 FTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPG-----VNYSGCQITWA 547
Query: 447 QFCKDALPERNFTFWEW 497
+FCK+ + + F+FW W
Sbjct: 548 KFCKENMAGKGFSFWVW 564
Score = 46.0 bits (104), Expect = 2e-04
Identities = 20/40 (50%), Positives = 27/40 (67%)
Frame = +2
Query: 515 VTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
+ + Y+ LW + IMGFI K++ +LS PPGTFLLRF
Sbjct: 571 LVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRF 610
Score = 32.3 bits (70), Expect = 2.0
Identities = 20/53 (37%), Positives = 32/53 (60%), Gaps = 1/53 (1%)
Frame = +1
Query: 85 VMDEKLTLL-FQSQFNVGGGELVFQVWTLSLPVVVIVHGNQEPHGWATVTWDN 240
++ E+L L+ F+++ G L + T SLPVVVI + Q P+ WA++ W N
Sbjct: 431 IVTEELHLITFETEVYHQG--LKIDLETHSLPVVVISNICQMPNAWASILWYN 481
>L29277-1|AAA58374.1| 770|Homo sapiens DNA-binding protein protein.
Length = 770
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/77 (35%), Positives = 40/77 (51%)
Frame = +3
Query: 267 FAVPDKVTWGQLAETLSLKFSSATGGSLSEDNLRFLAEKIFRTSLPLNTMELNAMAVSWT 446
F P TW Q+AE LS +FSS T LS + L LAEK+ + + ++W
Sbjct: 493 FTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPG-----VNYSGCQITWA 547
Query: 447 QFCKDALPERNFTFWEW 497
FCK+ + + F++W W
Sbjct: 548 NFCKENMAGKGFSYWVW 564
Score = 46.0 bits (104), Expect = 2e-04
Identities = 20/40 (50%), Positives = 27/40 (67%)
Frame = +2
Query: 515 VTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
+ + Y+ LW + IMGFI K++ +LS PPGTFLLRF
Sbjct: 571 LVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRF 610
>U18671-1|AAA98760.1| 851|Homo sapiens Stat2 protein.
Length = 851
Score = 47.6 bits (108), Expect = 5e-05
Identities = 40/139 (28%), Positives = 49/139 (35%), Gaps = 4/139 (2%)
Frame = +3
Query: 267 FAVPDKVTWGQLAETLSLKFSSATGGSLSEDNLRFLAEKIF----RTSLPLNTMELNAMA 434
F+ P K W L LS +FSS G L+ D L L K+F RT PL
Sbjct: 485 FSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTEDPL--------- 535
Query: 435 VSWTQFCKDALPERNFTFWEWFYMVSRSPGTTCGPCGATA**WASYRRSKLRICCPSVRP 614
+SW F K P FW W + RS+ R
Sbjct: 536 LSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKKTMS 595
Query: 615 GPSCCGSSDSELGGITIAW 671
G S+S GGIT +W
Sbjct: 596 GTFLLRFSESSEGGITCSW 614
Score = 44.4 bits (100), Expect = 5e-04
Identities = 19/41 (46%), Positives = 26/41 (63%)
Frame = +2
Query: 512 KVTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
++ D+L+ LW D IMGF+ + Q +L K GTFLLRF
Sbjct: 562 ELVHDHLKDLWNDGRIMGFVSRSQERRLLKKTMSGTFLLRF 602
Score = 36.3 bits (80), Expect = 0.12
Identities = 22/65 (33%), Positives = 33/65 (50%)
Frame = +1
Query: 58 RAEKKGTESVMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIVHGNQEPHGWATVTWD 237
+ KG V +E + F ++ G L ++ T +LPVV+I + NQ WA+V W
Sbjct: 415 KGSNKGPLGVTEELHIISFTVKYTYQG--LKQELKTDTLPVVIISNMNQLSIAWASVLWF 472
Query: 238 NAFSP 252
N SP
Sbjct: 473 NLLSP 477
>BC051284-1|AAH51284.1| 851|Homo sapiens signal transducer and
activator of transcription 2, 113kDa protein.
Length = 851
Score = 47.6 bits (108), Expect = 5e-05
Identities = 40/139 (28%), Positives = 49/139 (35%), Gaps = 4/139 (2%)
Frame = +3
Query: 267 FAVPDKVTWGQLAETLSLKFSSATGGSLSEDNLRFLAEKIF----RTSLPLNTMELNAMA 434
F+ P K W L LS +FSS G L+ D L L K+F RT PL
Sbjct: 485 FSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTEDPL--------- 535
Query: 435 VSWTQFCKDALPERNFTFWEWFYMVSRSPGTTCGPCGATA**WASYRRSKLRICCPSVRP 614
+SW F K P FW W + RS+ R
Sbjct: 536 LSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKKTMS 595
Query: 615 GPSCCGSSDSELGGITIAW 671
G S+S GGIT +W
Sbjct: 596 GTFLLRFSESSEGGITCSW 614
Score = 44.4 bits (100), Expect = 5e-04
Identities = 19/41 (46%), Positives = 26/41 (63%)
Frame = +2
Query: 512 KVTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
++ D+L+ LW D IMGF+ + Q +L K GTFLLRF
Sbjct: 562 ELVHDHLKDLWNDGRIMGFVSRSQERRLLKKTMSGTFLLRF 602
Score = 36.3 bits (80), Expect = 0.12
Identities = 22/65 (33%), Positives = 33/65 (50%)
Frame = +1
Query: 58 RAEKKGTESVMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIVHGNQEPHGWATVTWD 237
+ KG V +E + F ++ G L ++ T +LPVV+I + NQ WA+V W
Sbjct: 415 KGSNKGPLGVTEELHIISFTVKYTYQG--LKQELKTDTLPVVIISNMNQLSIAWASVLWF 472
Query: 238 NAFSP 252
N SP
Sbjct: 473 NLLSP 477
>AY525126-1|AAS00091.1| 851|Homo sapiens signal transducer and
activator of transcription 2, 113kDa protein.
Length = 851
Score = 47.6 bits (108), Expect = 5e-05
Identities = 40/139 (28%), Positives = 49/139 (35%), Gaps = 4/139 (2%)
Frame = +3
Query: 267 FAVPDKVTWGQLAETLSLKFSSATGGSLSEDNLRFLAEKIF----RTSLPLNTMELNAMA 434
F+ P K W L LS +FSS G L+ D L L K+F RT PL
Sbjct: 485 FSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTEDPL--------- 535
Query: 435 VSWTQFCKDALPERNFTFWEWFYMVSRSPGTTCGPCGATA**WASYRRSKLRICCPSVRP 614
+SW F K P FW W + RS+ R
Sbjct: 536 LSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKKTMS 595
Query: 615 GPSCCGSSDSELGGITIAW 671
G S+S GGIT +W
Sbjct: 596 GTFLLRFSESSEGGITCSW 614
Score = 44.4 bits (100), Expect = 5e-04
Identities = 19/41 (46%), Positives = 26/41 (63%)
Frame = +2
Query: 512 KVTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
++ D+L+ LW D IMGF+ + Q +L K GTFLLRF
Sbjct: 562 ELVHDHLKDLWNDGRIMGFVSRSQERRLLKKTMSGTFLLRF 602
Score = 36.3 bits (80), Expect = 0.12
Identities = 22/65 (33%), Positives = 33/65 (50%)
Frame = +1
Query: 58 RAEKKGTESVMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIVHGNQEPHGWATVTWD 237
+ KG V +E + F ++ G L ++ T +LPVV+I + NQ WA+V W
Sbjct: 415 KGSNKGPLGVTEELHIISFTVKYTYQG--LKQELKTDTLPVVIISNMNQLSIAWASVLWF 472
Query: 238 NAFSP 252
N SP
Sbjct: 473 NLLSP 477
>BX640607-1|CAE45713.1| 448|Homo sapiens hypothetical protein
protein.
Length = 448
Score = 47.2 bits (107), Expect = 7e-05
Identities = 40/139 (28%), Positives = 49/139 (35%), Gaps = 4/139 (2%)
Frame = +3
Query: 267 FAVPDKVTWGQLAETLSLKFSSATGGSLSEDNLRFLAEKIF----RTSLPLNTMELNAMA 434
F+ P K W L LS +FSS G L+ D L L K+F RT PL
Sbjct: 82 FSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTEDPL--------- 132
Query: 435 VSWTQFCKDALPERNFTFWEWFYMVSRSPGTTCGPCGATA**WASYRRSKLRICCPSVRP 614
+SW F K P FW W + RS+ R
Sbjct: 133 LSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQGRRLLKKTMS 192
Query: 615 GPSCCGSSDSELGGITIAW 671
G S+S GGIT +W
Sbjct: 193 GTFLLRFSESSEGGITCSW 211
Score = 44.8 bits (101), Expect = 3e-04
Identities = 19/41 (46%), Positives = 26/41 (63%)
Frame = +2
Query: 512 KVTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
++ D+L+ LW D IMGF+ + Q +L K GTFLLRF
Sbjct: 159 ELVHDHLKDLWNDGRIMGFVSRSQGRRLLKKTMSGTFLLRF 199
Score = 36.3 bits (80), Expect = 0.12
Identities = 22/65 (33%), Positives = 33/65 (50%)
Frame = +1
Query: 58 RAEKKGTESVMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIVHGNQEPHGWATVTWD 237
+ KG V +E + F ++ G L ++ T +LPVV+I + NQ WA+V W
Sbjct: 12 KGSNKGPLGVTEELHIISFTVKYTYQG--LKQELKTDTLPVVIISNMNQLSIAWASVLWF 69
Query: 238 NAFSP 252
N SP
Sbjct: 70 NLLSP 74
>AF029311-1|AAB84254.1| 141|Homo sapiens signal transducer and
activator of transcription 3 protein.
Length = 141
Score = 46.0 bits (104), Expect = 2e-04
Identities = 20/40 (50%), Positives = 27/40 (67%)
Frame = +2
Query: 515 VTRDYLRTLWCDRLIMGFIQKKQAEDMLSKCPPGTFLLRF 634
+ + Y+ LW + IMGFI K++ +LS PPGTFLLRF
Sbjct: 8 LVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRF 47
>BC006092-1|AAH06092.1| 577|Homo sapiens Unknown (protein for
IMAGE:4054862) protein.
Length = 577
Score = 45.6 bits (103), Expect = 2e-04
Identities = 29/81 (35%), Positives = 34/81 (41%), Gaps = 4/81 (4%)
Frame = +3
Query: 267 FAVPDKVTWGQLAETLSLKFSSATGGSLSEDNLRFLAEKIF----RTSLPLNTMELNAMA 434
F+ P K W L LS +FSS G L+ D L L K+F RT PL
Sbjct: 481 FSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTEDPL--------- 531
Query: 435 VSWTQFCKDALPERNFTFWEW 497
+SW F K P FW W
Sbjct: 532 LSWADFTKRESPPGKLPFWTW 552
Score = 36.3 bits (80), Expect = 0.12
Identities = 22/65 (33%), Positives = 33/65 (50%)
Frame = +1
Query: 58 RAEKKGTESVMDEKLTLLFQSQFNVGGGELVFQVWTLSLPVVVIVHGNQEPHGWATVTWD 237
+ KG V +E + F ++ G L ++ T +LPVV+I + NQ WA+V W
Sbjct: 411 KGSNKGPLGVTEELHIISFTVKYTYQG--LKQELKTDTLPVVIISNMNQLSIAWASVLWF 468
Query: 238 NAFSP 252
N SP
Sbjct: 469 NLLSP 473
>BC150248-1|AAI50249.1| 992|Homo sapiens ELKS/RAB6-interacting/CAST
family member 1 protein.
Length = 992
Score = 30.7 bits (66), Expect = 6.0
Identities = 13/33 (39%), Positives = 18/33 (54%)
Frame = +3
Query: 159 LDPVASGCGHSPRQPGAPRVGHRHVGQRLQSPG 257
++P + G SPR P +PR+GHR S G
Sbjct: 11 VEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSG 43
>BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
family member 1 protein.
Length = 1116
Score = 30.7 bits (66), Expect = 6.0
Identities = 13/33 (39%), Positives = 18/33 (54%)
Frame = +3
Query: 159 LDPVASGCGHSPRQPGAPRVGHRHVGQRLQSPG 257
++P + G SPR P +PR+GHR S G
Sbjct: 11 VEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSG 43
>BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
family member 1 protein.
Length = 1116
Score = 30.7 bits (66), Expect = 6.0
Identities = 13/33 (39%), Positives = 18/33 (54%)
Frame = +3
Query: 159 LDPVASGCGHSPRQPGAPRVGHRHVGQRLQSPG 257
++P + G SPR P +PR+GHR S G
Sbjct: 11 VEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSG 43
>BC068006-1|AAH68006.1| 627|Homo sapiens ERC1 protein protein.
Length = 627
Score = 30.7 bits (66), Expect = 6.0
Identities = 13/33 (39%), Positives = 18/33 (54%)
Frame = +3
Query: 159 LDPVASGCGHSPRQPGAPRVGHRHVGQRLQSPG 257
++P + G SPR P +PR+GHR S G
Sbjct: 11 VEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSG 43
>AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein.
Length = 1116
Score = 30.7 bits (66), Expect = 6.0
Identities = 13/33 (39%), Positives = 18/33 (54%)
Frame = +3
Query: 159 LDPVASGCGHSPRQPGAPRVGHRHVGQRLQSPG 257
++P + G SPR P +PR+GHR S G
Sbjct: 11 VEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSG 43
>AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein.
Length = 1088
Score = 30.7 bits (66), Expect = 6.0
Identities = 13/33 (39%), Positives = 18/33 (54%)
Frame = +3
Query: 159 LDPVASGCGHSPRQPGAPRVGHRHVGQRLQSPG 257
++P + G SPR P +PR+GHR S G
Sbjct: 11 VEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSG 43
>AB053469-1|BAC54108.1| 720|Homo sapiens ELKS gamma protein.
Length = 720
Score = 30.7 bits (66), Expect = 6.0
Identities = 13/33 (39%), Positives = 18/33 (54%)
Frame = +3
Query: 159 LDPVASGCGHSPRQPGAPRVGHRHVGQRLQSPG 257
++P + G SPR P +PR+GHR S G
Sbjct: 11 VEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSG 43
>AB053468-1|BAC54107.1| 992|Homo sapiens ELKS beta protein.
Length = 992
Score = 30.7 bits (66), Expect = 6.0
Identities = 13/33 (39%), Positives = 18/33 (54%)
Frame = +3
Query: 159 LDPVASGCGHSPRQPGAPRVGHRHVGQRLQSPG 257
++P + G SPR P +PR+GHR S G
Sbjct: 11 VEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSG 43
>AB029004-1|BAA83033.2| 1003|Homo sapiens KIAA1081 protein protein.
Length = 1003
Score = 30.7 bits (66), Expect = 6.0
Identities = 13/33 (39%), Positives = 18/33 (54%)
Frame = +3
Query: 159 LDPVASGCGHSPRQPGAPRVGHRHVGQRLQSPG 257
++P + G SPR P +PR+GHR S G
Sbjct: 22 VEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSG 54
>AB015617-1|BAA88763.1| 948|Homo sapiens ELKS protein.
Length = 948
Score = 30.7 bits (66), Expect = 6.0
Identities = 13/33 (39%), Positives = 18/33 (54%)
Frame = +3
Query: 159 LDPVASGCGHSPRQPGAPRVGHRHVGQRLQSPG 257
++P + G SPR P +PR+GHR S G
Sbjct: 11 VEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSG 43
>BC150172-1|AAI50173.1| 929|Homo sapiens protocadherin gamma
subfamily B, 3 protein.
Length = 929
Score = 30.3 bits (65), Expect = 8.0
Identities = 23/73 (31%), Positives = 33/73 (45%)
Frame = +3
Query: 237 QRLQSPGRVPFAVPDKVTWGQLAETLSLKFSSATGGSLSEDNLRFLAEKIFRTSLPLNTM 416
Q L P R +A+P+++ G L L+ G L NLR +AEK F T P N
Sbjct: 27 QALSEPIR--YAIPEELDRGSLVGNLAKDLGFGVG-DLPTRNLRVIAEKKFFTVSPENGN 83
Query: 417 ELNAMAVSWTQFC 455
L + + + C
Sbjct: 84 LLVSDRIDREEIC 96
>AF110315-1|AAD13107.1| 388|Homo sapiens unknown protein.
Length = 388
Score = 30.3 bits (65), Expect = 8.0
Identities = 15/36 (41%), Positives = 18/36 (50%), Gaps = 3/36 (8%)
Frame = -1
Query: 233 HVTVAHPWGSWL---PWTMTTTGSDRVQTWKTSSPP 135
H T + PW S L PWT T S+ +T T PP
Sbjct: 110 HWTQSTPWASALRSSPWTETAAPSETEETLNTGRPP 145
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 115,305,962
Number of Sequences: 237096
Number of extensions: 2687256
Number of successful extensions: 8688
Number of sequences better than 10.0: 50
Number of HSP's better than 10.0 without gapping: 7582
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8629
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9311505506
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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