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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= e96h0323
         (740 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q5S6Z7 Cluster: Vermilion; n=1; Bicyclus anynana|Rep: V...    89   1e-16
UniRef50_UPI00015B6095 Cluster: PREDICTED: similar to tryptophan...    66   1e-09
UniRef50_P20351 Cluster: Tryptophan 2,3-dioxygenase; n=47; Eumet...    59   1e-07
UniRef50_Q09474 Cluster: Putative tryptophan 2,3-dioxygenase; n=...    50   6e-05
UniRef50_Q55DB4 Cluster: Tryptophan 2,3-dioxygenase; n=1; Dictyo...    48   2e-04
UniRef50_P48775 Cluster: Tryptophan 2,3-dioxygenase; n=38; Coelo...    46   0.001
UniRef50_UPI0000E478ED Cluster: PREDICTED: similar to tryptophan...    45   0.002
UniRef50_A4B6L1 Cluster: Tryptophan 2,3-dioxygenase; n=1; Altero...    40   0.085
UniRef50_Q6MM37 Cluster: Tryptophan 2,3-dioxygenase; n=1; Bdello...    38   0.34 
UniRef50_Q7V1L0 Cluster: Conserved hypothetical precursor; n=1; ...    35   2.4  
UniRef50_Q3EU47 Cluster: Asparagine synthetase; n=1; Bacillus th...    34   4.2  
UniRef50_A3MTU9 Cluster: Putative uncharacterized protein; n=1; ...    34   4.2  
UniRef50_Q83CW8 Cluster: Prephenate dehydrogenase family protein...    33   5.6  
UniRef50_Q30KS8 Cluster: Beta-defensin 126; n=2; Canis lupus fam...    33   9.7  
UniRef50_Q54CV3 Cluster: Putative uncharacterized protein; n=1; ...    33   9.7  

>UniRef50_Q5S6Z7 Cluster: Vermilion; n=1; Bicyclus anynana|Rep:
           Vermilion - Bicyclus anynana (squinting bush brown)
          Length = 175

 Score = 89.0 bits (211), Expect = 1e-16
 Identities = 39/55 (70%), Positives = 48/55 (87%)
 Frame = -1

Query: 260 IKDRYKVFLDLFNLSTFLLPRALIPPLDEDMKRSLNLTWGDNVRENGDETTPQNG 96
           + DRYKVFLDLFNLSTFLLPR+LIPPLD+ +KR L+LTWGD++RENG  +  +NG
Sbjct: 96  LSDRYKVFLDLFNLSTFLLPRSLIPPLDDGIKRDLSLTWGDHIRENG-RSAKENG 149


>UniRef50_UPI00015B6095 Cluster: PREDICTED: similar to tryptophan
           oxygenase; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to tryptophan oxygenase - Nasonia vitripennis
          Length = 423

 Score = 65.7 bits (153), Expect = 1e-09
 Identities = 29/52 (55%), Positives = 39/52 (75%), Gaps = 1/52 (1%)
 Frame = -1

Query: 260 IKDRYKVFLDLFNLSTFLLPRALIPPLDEDMKRSLNLTWGD-NVRENGDETT 108
           + DRYKVF+DLFNLSTFL+PR LIPPL + MK  L++ WG   + +  D+T+
Sbjct: 339 LSDRYKVFVDLFNLSTFLIPRQLIPPLTKGMKTKLSMAWGYWGLEDEEDDTS 390


>UniRef50_P20351 Cluster: Tryptophan 2,3-dioxygenase; n=47;
           Eumetazoa|Rep: Tryptophan 2,3-dioxygenase - Drosophila
           melanogaster (Fruit fly)
          Length = 379

 Score = 59.3 bits (137), Expect = 1e-07
 Identities = 25/35 (71%), Positives = 30/35 (85%)
 Frame = -1

Query: 260 IKDRYKVFLDLFNLSTFLLPRALIPPLDEDMKRSL 156
           + DRYKVFLDLFNLSTFL+PR  IPPLDE +++ L
Sbjct: 340 LSDRYKVFLDLFNLSTFLIPREAIPPLDETIRKKL 374


>UniRef50_Q09474 Cluster: Putative tryptophan 2,3-dioxygenase; n=3;
           Caenorhabditis|Rep: Putative tryptophan 2,3-dioxygenase
           - Caenorhabditis elegans
          Length = 403

 Score = 50.0 bits (114), Expect = 6e-05
 Identities = 32/63 (50%), Positives = 40/63 (63%)
 Frame = -1

Query: 341 RYNGAKDDRVATARDRGLVWLSVSTVNIKDRYKVFLDLFNLSTFLLPRALIPPLDEDMKR 162
           R  GAK     T    G ++L  STV+  DRYKVFLDLFNLST+L+PR  IP L   M +
Sbjct: 333 RMLGAKQ---GTGGSSGYMYLR-STVS--DRYKVFLDLFNLSTWLIPREYIPMLSPRMVK 386

Query: 161 SLN 153
           +L+
Sbjct: 387 TLS 389


>UniRef50_Q55DB4 Cluster: Tryptophan 2,3-dioxygenase; n=1;
           Dictyostelium discoideum AX4|Rep: Tryptophan
           2,3-dioxygenase - Dictyostelium discoideum AX4
          Length = 400

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 17/39 (43%), Positives = 29/39 (74%)
 Frame = -1

Query: 260 IKDRYKVFLDLFNLSTFLLPRALIPPLDEDMKRSLNLTW 144
           + DRYK+FLDLFN+S++L+P+  +P L + +K  ++  W
Sbjct: 359 VGDRYKIFLDLFNISSYLIPKNTLPQLPKVVKEQMDFAW 397


>UniRef50_P48775 Cluster: Tryptophan 2,3-dioxygenase; n=38;
           Coelomata|Rep: Tryptophan 2,3-dioxygenase - Homo sapiens
           (Human)
          Length = 406

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 19/35 (54%), Positives = 27/35 (77%)
 Frame = -1

Query: 260 IKDRYKVFLDLFNLSTFLLPRALIPPLDEDMKRSL 156
           + DRYKVF+DLFNLST+L+PR  IP ++  + + L
Sbjct: 355 VSDRYKVFVDLFNLSTYLIPRHWIPKMNPTIHKFL 389


>UniRef50_UPI0000E478ED Cluster: PREDICTED: similar to tryptophan
           2,3-dioxygenase; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to tryptophan 2,3-dioxygenase -
           Strongylocentrotus purpuratus
          Length = 413

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 18/36 (50%), Positives = 26/36 (72%)
 Frame = -1

Query: 260 IKDRYKVFLDLFNLSTFLLPRALIPPLDEDMKRSLN 153
           I D+Y++FLDLFNLS + LP+  +P L + MK  L+
Sbjct: 376 ISDKYRIFLDLFNLSNYYLPQEFVPELTDGMKAILS 411


>UniRef50_A4B6L1 Cluster: Tryptophan 2,3-dioxygenase; n=1;
           Alteromonas macleodii 'Deep ecotype'|Rep: Tryptophan
           2,3-dioxygenase - Alteromonas macleodii 'Deep ecotype'
          Length = 362

 Score = 39.5 bits (88), Expect = 0.085
 Identities = 14/30 (46%), Positives = 24/30 (80%)
 Frame = -1

Query: 245 KVFLDLFNLSTFLLPRALIPPLDEDMKRSL 156
           +++LD FN++TFLLP++ +P L E ++R L
Sbjct: 328 RIYLDFFNMATFLLPKSALPDLPESVRRRL 357


>UniRef50_Q6MM37 Cluster: Tryptophan 2,3-dioxygenase; n=1;
           Bdellovibrio bacteriovorus|Rep: Tryptophan
           2,3-dioxygenase - Bdellovibrio bacteriovorus
          Length = 359

 Score = 37.5 bits (83), Expect = 0.34
 Identities = 17/46 (36%), Positives = 29/46 (63%)
 Frame = -1

Query: 317 RVATARDRGLVWLSVSTVNIKDRYKVFLDLFNLSTFLLPRALIPPL 180
           ++ T    G  +L+ +T     ++K+F D FNL+TF +PR+ +PPL
Sbjct: 306 KIGTGGSSGHKYLADATA----KHKIFGDFFNLTTFFIPRSQVPPL 347


>UniRef50_Q7V1L0 Cluster: Conserved hypothetical precursor; n=1;
           Prochlorococcus marinus subsp. pastoris str.
           CCMP1986|Rep: Conserved hypothetical precursor -
           Prochlorococcus marinus subsp. pastoris (strain CCMP
           1378 / MED4)
          Length = 257

 Score = 34.7 bits (76), Expect = 2.4
 Identities = 20/53 (37%), Positives = 33/53 (62%)
 Frame = +3

Query: 360 SHDYLNERQI*I*ILFVVHSSLHLFDLLEKILMKKLNSPLSTYFFIFKIVNYF 518
           +++YL +  I   ILF+V +S+ L     K L+KK+   + T FFIF I+N++
Sbjct: 119 NNEYLVQYDIDKQILFIVITSIFLIFKKTKFLLKKI---ILTNFFIFSIINWY 168


>UniRef50_Q3EU47 Cluster: Asparagine synthetase; n=1; Bacillus
           thuringiensis serovar israelensis ATCC 35646|Rep:
           Asparagine synthetase - Bacillus thuringiensis serovar
           israelensis ATCC 35646
          Length = 646

 Score = 33.9 bits (74), Expect = 4.2
 Identities = 16/38 (42%), Positives = 23/38 (60%)
 Frame = -2

Query: 709 YTIYRASKLRHLCEENP*KSSSRQYLFSKTVSYLIYIN 596
           Y I++ +K+R  CE +P KS  R  L+ KT SY+   N
Sbjct: 382 YDIFKEAKIRAFCERDP-KSKLRPLLYKKTNSYINNFN 418


>UniRef50_A3MTU9 Cluster: Putative uncharacterized protein; n=1;
           Pyrobaculum calidifontis JCM 11548|Rep: Putative
           uncharacterized protein - Pyrobaculum calidifontis
           (strain JCM 11548 / VA1)
          Length = 461

 Score = 33.9 bits (74), Expect = 4.2
 Identities = 13/43 (30%), Positives = 26/43 (60%)
 Frame = -1

Query: 236 LDLFNLSTFLLPRALIPPLDEDMKRSLNLTWGDNVRENGDETT 108
           ++L N++ ++LP+AL P ++E +K+       + VRE  +  T
Sbjct: 84  MELMNIAIYVLPKALAPSVEEALKKVFTFDLDELVREGANHAT 126


>UniRef50_Q83CW8 Cluster: Prephenate dehydrogenase family protein;
           n=4; Coxiella burnetii|Rep: Prephenate dehydrogenase
           family protein - Coxiella burnetii
          Length = 258

 Score = 33.5 bits (73), Expect = 5.6
 Identities = 12/30 (40%), Positives = 21/30 (70%)
 Frame = +2

Query: 323 PLHHYNVVVCKIESRLLKRTTNLNINSFCC 412
           P+HH+   + KI S+L+K+TT +++ S  C
Sbjct: 64  PIHHFKNTIIKIASKLIKKTTVIDVCSVKC 93


>UniRef50_Q30KS8 Cluster: Beta-defensin 126; n=2; Canis lupus
           familiaris|Rep: Beta-defensin 126 - Canis familiaris
           (Dog)
          Length = 145

 Score = 32.7 bits (71), Expect = 9.7
 Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 3/67 (4%)
 Frame = -2

Query: 223 ICPRS--CCLVP*YRHWTKT*NAASISHGETTS-GKTEMRRPRKTALKLLYNEKL*CVLT 53
           +CP+   CC++      TKT N+A  S   TT+ G     R       LL+  K   +++
Sbjct: 51  MCPKEKMCCILSACGETTKTTNSAQASESSTTTPGPRTSPRVSPELRSLLHRSKGFTLVS 110

Query: 52  IFLRHIL 32
           +FL H+L
Sbjct: 111 LFLLHLL 117


>UniRef50_Q54CV3 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 639

 Score = 32.7 bits (71), Expect = 9.7
 Identities = 15/44 (34%), Positives = 25/44 (56%)
 Frame = -1

Query: 284 WLSVSTVNIKDRYKVFLDLFNLSTFLLPRALIPPLDEDMKRSLN 153
           WL    +  ++     L ++++S F   +  I P+DEDMK+SLN
Sbjct: 151 WLITKVIETREETGDLLRMYSISMF--SKDYIAPIDEDMKKSLN 192


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 662,340,809
Number of Sequences: 1657284
Number of extensions: 12826065
Number of successful extensions: 30347
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 29287
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 30336
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 60500186565
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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