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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= e96h0302
         (468 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC002862-1|AAH02862.1|  307|Homo sapiens AKR1CL2 protein protein.      72   1e-12
AF263242-1|AAK58523.1|  320|Homo sapiens aldo-keto reductase loo...    72   1e-12
AB055603-1|BAC54568.1|  307|Homo sapiens aldo-keto reductase rel...    72   1e-12
AB040822-1|BAC54567.1|  222|Homo sapiens aldo-keto reductase rel...    72   1e-12
AB040821-1|BAC54566.1|  263|Homo sapiens aldo-keto reductase rel...    72   1e-12
AB040820-1|BAC54565.1|  250|Homo sapiens aldo-keto reductase rel...    72   1e-12
AF149416-1|AAF07272.2|  323|Homo sapiens 3-alpha hydroxysteroid ...    71   2e-12
D17793-1|BAA04619.2|  325|Homo sapiens KIAA0119 protein.               70   4e-12
BT007286-1|AAP35950.1|  323|Homo sapiens aldo-keto reductase fam...    70   4e-12
BC019230-1|AAH19230.1|  323|Homo sapiens aldo-keto reductase fam...    70   4e-12
BC001479-1|AAH01479.1|  323|Homo sapiens aldo-keto reductase fam...    70   4e-12
AL391427-4|CAI14729.1|  323|Homo sapiens aldo-keto reductase fam...    70   4e-12
AB032157-1|BAA92892.1|  323|Homo sapiens prostaglandin F synthas...    70   4e-12
AB018580-1|BAA88488.1|  323|Homo sapiens hluPGFS protein.              70   4e-12
U05598-1|AAA20937.1|  323|Homo sapiens dihydrodiol dehydrogenase...    69   6e-12
S68330-1|AAD14013.1|  323|Homo sapiens chlordecone reductase hom...    69   6e-12
BT006653-1|AAP35299.1|  323|Homo sapiens aldo-keto reductase fam...    69   6e-12
BC063574-1|AAH63574.1|  323|Homo sapiens aldo-keto reductase fam...    69   6e-12
BC007024-1|AAH07024.1|  323|Homo sapiens aldo-keto reductase fam...    69   6e-12
AL713867-1|CAI16408.1|  323|Homo sapiens aldo-keto reductase fam...    69   6e-12
AL391427-1|CAI14726.1|  323|Homo sapiens aldo-keto reductase fam...    69   6e-12
AB209017-1|BAD92254.1|  286|Homo sapiens aldo-keto reductase fam...    69   6e-12
AB032153-1|BAA92891.1|  323|Homo sapiens bile acid-binding prote...    69   6e-12
AB031084-1|BAA92884.1|  323|Homo sapiens bile acid-binding prote...    69   6e-12
AB021654-1|BAA36169.1|  323|Homo sapiens DD2/bile acid-binding p...    69   6e-12
S68288-1|AAD14011.1|  323|Homo sapiens chlordecone reductase hom...    69   1e-11
U05861-1|AAA18115.1|  323|Homo sapiens hepatic dihydrodiol dehyd...    68   2e-11
U05684-1|AAA16227.1|  323|Homo sapiens dihydrodiol dehydrogenase...    68   2e-11
M86609-1|AAB02880.1|  323|Homo sapiens dihydrodiol dehydrogenase...    68   2e-11
L43839-1|AAB41916.1|  323|Homo sapiens 3-alpha-hydroxysteroid de...    68   2e-11
L32592-1|AAB38486.1|  323|Homo sapiens dihydrodiol dehydrogenase...    68   2e-11
D26124-1|BAA05121.1|  306|Homo sapiens dihydrodiol dehydrogenase...    68   2e-11
BT007197-1|AAP35861.1|  323|Homo sapiens aldo-keto reductase fam...    68   2e-11
BC040210-1|AAH40210.1|  323|Homo sapiens aldo-keto reductase fam...    68   2e-11
BC020216-1|AAH20216.1|  323|Homo sapiens aldo-keto reductase fam...    68   2e-11
BC015490-1|AAH15490.1|  323|Homo sapiens aldo-keto reductase fam...    68   2e-11
AL713867-3|CAI16410.1|  247|Homo sapiens aldo-keto reductase fam...    68   2e-11
AL713867-2|CAI16409.1|  323|Homo sapiens aldo-keto reductase fam...    68   2e-11
AB032150-1|BAA92886.1|  323|Homo sapiens 20 alph-hydroxysteroid ...    68   2e-11
AB031083-1|BAA92883.1|  323|Homo sapiens 20 alpha-hydroxysteroid...    68   2e-11
S68287-1|AAD14010.1|  323|Homo sapiens chlordecone reductase pro...    67   2e-11
M33375-1|AAA35658.1|  308|Homo sapiens protein ( Human chlordeco...    67   2e-11
D26125-1|BAA05122.1|  321|Homo sapiens 3 alpha-hydroxysteroid/di...    67   2e-11
BC020744-1|AAH20744.1|  323|Homo sapiens aldo-keto reductase fam...    67   2e-11
AL355303-2|CAI14202.1|  323|Homo sapiens aldo-keto reductase fam...    67   2e-11
AB045829-1|BAA99542.1|  323|Homo sapiens 3alpha-hydroxysteroid d...    67   2e-11
AB032163-1|BAA92893.1|  323|Homo sapiens dihydrodiol dehydrogena...    67   2e-11
AB031085-1|BAA92885.1|  323|Homo sapiens dihydrodiol dehydrogena...    67   2e-11
DQ269985-1|ABB76132.1|  323|Homo sapiens type II 3a-hydroxystero...    66   4e-11
CR542203-1|CAG47000.1|  316|Homo sapiens AKR1B1 protein.               65   1e-10
S68290-1|AAD14012.1|  320|Homo sapiens chlordecone reductase hom...    65   1e-10
J04794-1|AAA51711.1|  325|Homo sapiens ALDR1 protein.                  64   2e-10
CR457010-1|CAG33291.1|  325|Homo sapiens AKR1A1 protein.               64   2e-10
BT007003-1|AAP35649.1|  325|Homo sapiens aldo-keto reductase fam...    64   2e-10
BC005394-1|AAH05394.1|  325|Homo sapiens aldo-keto reductase fam...    64   2e-10
BC000670-1|AAH00670.1|  325|Homo sapiens aldo-keto reductase fam...    64   2e-10
AL355480-3|CAI22459.1|  325|Homo sapiens aldo-keto reductase fam...    64   2e-10
AL355480-2|CAI22458.1|  147|Homo sapiens aldo-keto reductase fam...    64   2e-10
AF112485-1|AAF01260.1|  325|Homo sapiens aldehyde reductase prot...    64   2e-10
AF036683-1|AAB92369.1|  325|Homo sapiens aldehyde reductase prot...    64   2e-10
X15414-1|CAA33460.1|  316|Homo sapiens protein ( Human mRNA for ...    63   4e-10
M59783-1|AAA51712.1|  316|Homo sapiens aldose reductase protein.       63   4e-10
M34720-1|AAA35560.1|  316|Homo sapiens protein ( Human aldose re...    63   4e-10
J05474-1|AAA51715.1|  316|Homo sapiens aldose reductase protein.       63   4e-10
J05017-1|AAA51714.1|  316|Homo sapiens ALDR1 protein.                  63   4e-10
J04795-1|AAA51713.1|  316|Homo sapiens ALDR1 protein.                  63   4e-10
CR450351-1|CAG29347.1|  316|Homo sapiens AKR1B1 protein.               63   4e-10
BT019859-1|AAV38662.1|  316|Homo sapiens aldo-keto reductase fam...    63   4e-10
BC010391-1|AAH10391.1|  316|Homo sapiens aldo-keto reductase fam...    63   4e-10
BC005387-1|AAH05387.1|  316|Homo sapiens aldo-keto reductase fam...    63   4e-10
BC000260-1|AAH00260.1|  316|Homo sapiens aldo-keto reductase fam...    63   4e-10
AF328729-1|AAN09721.1|  316|Homo sapiens CTCL tumor antigen HD-C...    63   4e-10
AF032455-1|AAB88851.1|  316|Homo sapiens aldose reductase protein.     63   4e-10
AB209796-1|BAD93033.1|  260|Homo sapiens aldo-keto reductase fam...    63   4e-10
AB037902-1|BAA92887.1|  130|Homo sapiens truncated aldo-keto red...    63   4e-10
U37100-1|AAC17469.1|  316|Homo sapiens aldose reductase-like pep...    61   2e-09
CR541801-1|CAG46600.1|  316|Homo sapiens AKR1B10 protein.              61   2e-09
BT006794-1|AAP35440.1|  316|Homo sapiens aldo-keto reductase fam...    61   2e-09
BC008837-1|AAH08837.1|  316|Homo sapiens aldo-keto reductase fam...    61   2e-09
AF052577-1|AAC36465.1|  316|Homo sapiens aldo-keto reductase pro...    61   2e-09
BC101205-1|AAI01206.1|  129|Homo sapiens aldo-keto reductase fam...    61   2e-09
BC101204-1|AAI01205.1|  129|Homo sapiens aldo-keto reductase fam...    61   2e-09
AL391427-2|CAI14727.1|  302|Homo sapiens aldo-keto reductase fam...    61   2e-09
AL355303-1|CAI14201.1|  302|Homo sapiens aldo-keto reductase fam...    61   2e-09
AK131335-1|BAD18494.1|  129|Homo sapiens protein ( Homo sapiens ...    61   2e-09
AF524864-1|AAO13380.1|  316|Homo sapiens aldo-ketoreductase prot...    58   1e-08
Z28339-1|CAA82193.1|  326|Homo sapiens delta 4-3-oxosteroid 5 be...    51   2e-06
BC130627-1|AAI30628.1|  326|Homo sapiens aldo-keto reductase fam...    51   2e-06
BC130625-1|AAI30626.1|  326|Homo sapiens aldo-keto reductase fam...    51   2e-06
AF283659-1|AAG39381.1|  326|Homo sapiens 5-beta steroid reductas...    51   2e-06
AB037905-2|BAA92890.1|   45|Homo sapiens truncated aldo-keto red...    40   0.004
AK125347-1|BAC86140.1|  277|Homo sapiens protein ( Homo sapiens ...    29   6.1  

>BC002862-1|AAH02862.1|  307|Homo sapiens AKR1CL2 protein protein.
          Length = 307

 Score = 71.7 bits (168), Expect = 1e-12
 Identities = 30/56 (53%), Positives = 41/56 (73%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 422
           + K+  G V+RED+FI TKLW T H+++ V  A   SLK L L+Y+DLYL+HWP+G
Sbjct: 51  RCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106



 Score = 42.3 bits (95), Expect = 8e-04
 Identities = 21/60 (35%), Positives = 33/60 (55%)
 Frame = +1

Query: 85  DMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIXEXVRXR 264
           D+PA+GL ++         K+   ++ + V  AID GYRHFD A  Y  E+E+   +R +
Sbjct: 3   DIPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCK 53


>AF263242-1|AAK58523.1|  320|Homo sapiens aldo-keto reductase
           loopADR protein.
          Length = 320

 Score = 71.7 bits (168), Expect = 1e-12
 Identities = 30/56 (53%), Positives = 41/56 (73%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 422
           + K+  G V+RED+FI TKLW T H+++ V  A   SLK L L+Y+DLYL+HWP+G
Sbjct: 51  RCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106



 Score = 42.3 bits (95), Expect = 8e-04
 Identities = 21/60 (35%), Positives = 33/60 (55%)
 Frame = +1

Query: 85  DMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIXEXVRXR 264
           D+PA+GL ++         K+   ++ + V  AID GYRHFD A  Y  E+E+   +R +
Sbjct: 3   DIPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCK 53


>AB055603-1|BAC54568.1|  307|Homo sapiens aldo-keto reductase
           related protein 4 protein.
          Length = 307

 Score = 71.7 bits (168), Expect = 1e-12
 Identities = 30/56 (53%), Positives = 41/56 (73%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 422
           + K+  G V+RED+FI TKLW T H+++ V  A   SLK L L+Y+DLYL+HWP+G
Sbjct: 51  RCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106



 Score = 42.3 bits (95), Expect = 8e-04
 Identities = 21/60 (35%), Positives = 33/60 (55%)
 Frame = +1

Query: 85  DMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIXEXVRXR 264
           D+PA+GL ++         K+   ++ + V  AID GYRHFD A  Y  E+E+   +R +
Sbjct: 3   DIPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCK 53


>AB040822-1|BAC54567.1|  222|Homo sapiens aldo-keto reductase
           related protein 3 protein.
          Length = 222

 Score = 71.7 bits (168), Expect = 1e-12
 Identities = 30/56 (53%), Positives = 41/56 (73%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 422
           + K+  G V+RED+FI TKLW T H+++ V  A   SLK L L+Y+DLYL+HWP+G
Sbjct: 51  RCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106



 Score = 42.3 bits (95), Expect = 8e-04
 Identities = 21/60 (35%), Positives = 33/60 (55%)
 Frame = +1

Query: 85  DMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIXEXVRXR 264
           D+PA+GL ++         K+   ++ + V  AID GYRHFD A  Y  E+E+   +R +
Sbjct: 3   DIPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCK 53


>AB040821-1|BAC54566.1|  263|Homo sapiens aldo-keto reductase
           related protein 2 protein.
          Length = 263

 Score = 71.7 bits (168), Expect = 1e-12
 Identities = 30/56 (53%), Positives = 41/56 (73%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 422
           + K+  G V+RED+FI TKLW T H+++ V  A   SLK L L+Y+DLYL+HWP+G
Sbjct: 51  RCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106



 Score = 42.3 bits (95), Expect = 8e-04
 Identities = 21/60 (35%), Positives = 33/60 (55%)
 Frame = +1

Query: 85  DMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIXEXVRXR 264
           D+PA+GL ++         K+   ++ + V  AID GYRHFD A  Y  E+E+   +R +
Sbjct: 3   DIPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCK 53


>AB040820-1|BAC54565.1|  250|Homo sapiens aldo-keto reductase
           related protein 1 protein.
          Length = 250

 Score = 71.7 bits (168), Expect = 1e-12
 Identities = 30/56 (53%), Positives = 41/56 (73%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 422
           + K+  G V+RED+FI TKLW T H+++ V  A   SLK L L+Y+DLYL+HWP+G
Sbjct: 51  RCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106



 Score = 42.3 bits (95), Expect = 8e-04
 Identities = 21/60 (35%), Positives = 33/60 (55%)
 Frame = +1

Query: 85  DMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIXEXVRXR 264
           D+PA+GL ++         K+   ++ + V  AID GYRHFD A  Y  E+E+   +R +
Sbjct: 3   DIPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCK 53


>AF149416-1|AAF07272.2|  323|Homo sapiens 3-alpha hydroxysteroid
           dehydrogenase type IIb protein.
          Length = 323

 Score = 71.3 bits (167), Expect = 2e-12
 Identities = 32/57 (56%), Positives = 41/57 (71%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW+T HR   V  A+ +SLKK  LDY+DLYL+H P+ L
Sbjct: 66  RSKIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLIHSPMSL 122



 Score = 44.8 bits (101), Expect = 2e-04
 Identities = 22/67 (32%), Positives = 40/67 (59%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V +SK  ++  +   AI+ G+RH D+A +Y  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPPE---VPRSKALEVSKL---AIEAGFRHIDSAHLYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>D17793-1|BAA04619.2|  325|Homo sapiens KIAA0119 protein.
          Length = 325

 Score = 70.1 bits (164), Expect = 4e-12
 Identities = 32/57 (56%), Positives = 41/57 (71%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW+T HR   V  A+ +SLKK  LDY+DLYL+H P+ L
Sbjct: 68  RSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSL 124



 Score = 45.6 bits (103), Expect = 9e-05
 Identities = 23/67 (34%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V +SK     +V   AI+ G+RH D+A +Y  E+++
Sbjct: 10  VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVTKLAIEAGFRHIDSAHLYNNEEQV 63

Query: 244 XEXVRXR 264
              +R +
Sbjct: 64  GLAIRSK 70


>BT007286-1|AAP35950.1|  323|Homo sapiens aldo-keto reductase family
           1, member C3 (3-alpha hydroxysteroid dehydrogenase,
           protein.
          Length = 323

 Score = 70.1 bits (164), Expect = 4e-12
 Identities = 32/57 (56%), Positives = 41/57 (71%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW+T HR   V  A+ +SLKK  LDY+DLYL+H P+ L
Sbjct: 66  RSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSL 122



 Score = 45.6 bits (103), Expect = 9e-05
 Identities = 23/67 (34%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V +SK     +V   AI+ G+RH D+A +Y  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVTKLAIEAGFRHIDSAHLYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>BC019230-1|AAH19230.1|  323|Homo sapiens aldo-keto reductase family
           1, member C3 (3-alpha hydroxysteroid dehydrogenase,
           protein.
          Length = 323

 Score = 70.1 bits (164), Expect = 4e-12
 Identities = 32/57 (56%), Positives = 41/57 (71%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW+T HR   V  A+ +SLKK  LDY+DLYL+H P+ L
Sbjct: 66  RSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSL 122



 Score = 45.6 bits (103), Expect = 9e-05
 Identities = 23/67 (34%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V +SK     +V   AI+ G+RH D+A +Y  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVTKLAIEAGFRHIDSAHLYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>BC001479-1|AAH01479.1|  323|Homo sapiens aldo-keto reductase family
           1, member C3 (3-alpha hydroxysteroid dehydrogenase,
           protein.
          Length = 323

 Score = 70.1 bits (164), Expect = 4e-12
 Identities = 32/57 (56%), Positives = 41/57 (71%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW+T HR   V  A+ +SLKK  LDY+DLYL+H P+ L
Sbjct: 66  RSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSL 122



 Score = 45.6 bits (103), Expect = 9e-05
 Identities = 23/67 (34%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V +SK     +V   AI+ G+RH D+A +Y  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVTKLAIEAGFRHIDSAHLYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>AL391427-4|CAI14729.1|  323|Homo sapiens aldo-keto reductase family
           1, member C3 (3-alpha hydroxysteroid dehydrogenase,
           protein.
          Length = 323

 Score = 70.1 bits (164), Expect = 4e-12
 Identities = 32/57 (56%), Positives = 41/57 (71%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW+T HR   V  A+ +SLKK  LDY+DLYL+H P+ L
Sbjct: 66  RSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSL 122



 Score = 45.6 bits (103), Expect = 9e-05
 Identities = 23/67 (34%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V +SK     +V   AI+ G+RH D+A +Y  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVTKLAIEAGFRHIDSAHLYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>AB032157-1|BAA92892.1|  323|Homo sapiens prostaglandin F synthase
           protein.
          Length = 323

 Score = 70.1 bits (164), Expect = 4e-12
 Identities = 32/57 (56%), Positives = 41/57 (71%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW+T HR   V  A+ +SLKK  LDY+DLYL+H P+ L
Sbjct: 66  RSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSL 122



 Score = 45.6 bits (103), Expect = 9e-05
 Identities = 23/67 (34%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V +SK     +V   AI+ G+RH D+A +Y  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVTKLAIEAGFRHIDSAHLYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>AB018580-1|BAA88488.1|  323|Homo sapiens hluPGFS protein.
          Length = 323

 Score = 70.1 bits (164), Expect = 4e-12
 Identities = 32/57 (56%), Positives = 41/57 (71%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW+T HR   V  A+ +SLKK  LDY+DLYL+H P+ L
Sbjct: 66  RSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSL 122



 Score = 45.6 bits (103), Expect = 9e-05
 Identities = 23/67 (34%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V +SK     +V   AI+ G+RH D+A +Y  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVTKLAIEAGFRHIDSAHLYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>U05598-1|AAA20937.1|  323|Homo sapiens dihydrodiol dehydrogenase
           protein.
          Length = 323

 Score = 69.3 bits (162), Expect = 6e-12
 Identities = 30/57 (52%), Positives = 40/57 (70%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW+  HR   V  A+  SLK L LDY+DLYL+H+P+ +
Sbjct: 66  RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122



 Score = 46.0 bits (104), Expect = 7e-05
 Identities = 24/67 (35%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V KSK     + V  AI+ G+ H D+A VY  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>S68330-1|AAD14013.1|  323|Homo sapiens chlordecone reductase
           homolog protein.
          Length = 323

 Score = 69.3 bits (162), Expect = 6e-12
 Identities = 30/57 (52%), Positives = 40/57 (70%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW+  HR   V  A+  SLK L LDY+DLYL+H+P+ +
Sbjct: 66  RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122



 Score = 46.0 bits (104), Expect = 7e-05
 Identities = 24/67 (35%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V KSK     + V  AI+ G+ H D+A VY  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>BT006653-1|AAP35299.1|  323|Homo sapiens aldo-keto reductase family
           1, member C2 (dihydrodiol dehydrogenase 2; bile acid
           protein.
          Length = 323

 Score = 69.3 bits (162), Expect = 6e-12
 Identities = 30/57 (52%), Positives = 40/57 (70%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW+  HR   V  A+  SLK L LDY+DLYL+H+P+ +
Sbjct: 66  RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122



 Score = 46.0 bits (104), Expect = 7e-05
 Identities = 24/67 (35%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V KSK     + V  AI+ G+ H D+A VY  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>BC063574-1|AAH63574.1|  323|Homo sapiens aldo-keto reductase family
           1, member C2 (dihydrodiol dehydrogenase 2; bile acid
           protein.
          Length = 323

 Score = 69.3 bits (162), Expect = 6e-12
 Identities = 30/57 (52%), Positives = 40/57 (70%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW+  HR   V  A+  SLK L LDY+DLYL+H+P+ +
Sbjct: 66  RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122



 Score = 46.0 bits (104), Expect = 7e-05
 Identities = 24/67 (35%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V KSK     + V  AI+ G+ H D+A VY  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>BC007024-1|AAH07024.1|  323|Homo sapiens aldo-keto reductase family
           1, member C2 (dihydrodiol dehydrogenase 2; bile acid
           protein.
          Length = 323

 Score = 69.3 bits (162), Expect = 6e-12
 Identities = 30/57 (52%), Positives = 40/57 (70%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW+  HR   V  A+  SLK L LDY+DLYL+H+P+ +
Sbjct: 66  RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122



 Score = 46.0 bits (104), Expect = 7e-05
 Identities = 24/67 (35%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V KSK     + V  AI+ G+ H D+A VY  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>AL713867-1|CAI16408.1|  323|Homo sapiens aldo-keto reductase family
           1, member C2 (dihydrodiol dehydrogenase 2; bile acid
           protein.
          Length = 323

 Score = 69.3 bits (162), Expect = 6e-12
 Identities = 30/57 (52%), Positives = 40/57 (70%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW+  HR   V  A+  SLK L LDY+DLYL+H+P+ +
Sbjct: 66  RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122



 Score = 46.0 bits (104), Expect = 7e-05
 Identities = 24/67 (35%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V KSK     + V  AI+ G+ H D+A VY  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>AL391427-1|CAI14726.1|  323|Homo sapiens aldo-keto reductase family
           1, member C2 (dihydrodiol dehydrogenase 2; bile acid
           protein.
          Length = 323

 Score = 69.3 bits (162), Expect = 6e-12
 Identities = 30/57 (52%), Positives = 40/57 (70%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW+  HR   V  A+  SLK L LDY+DLYL+H+P+ +
Sbjct: 66  RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122



 Score = 46.0 bits (104), Expect = 7e-05
 Identities = 24/67 (35%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V KSK     + V  AI+ G+ H D+A VY  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>AB209017-1|BAD92254.1|  286|Homo sapiens aldo-keto reductase family
           1, member C2 variant protein.
          Length = 286

 Score = 69.3 bits (162), Expect = 6e-12
 Identities = 30/57 (52%), Positives = 40/57 (70%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW+  HR   V  A+  SLK L LDY+DLYL+H+P+ +
Sbjct: 79  RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 135



 Score = 46.0 bits (104), Expect = 7e-05
 Identities = 24/67 (35%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V KSK     + V  AI+ G+ H D+A VY  E+++
Sbjct: 21  VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVYNNEEQV 74

Query: 244 XEXVRXR 264
              +R +
Sbjct: 75  GLAIRSK 81


>AB032153-1|BAA92891.1|  323|Homo sapiens bile acid-binding protein
           protein.
          Length = 323

 Score = 69.3 bits (162), Expect = 6e-12
 Identities = 30/57 (52%), Positives = 40/57 (70%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW+  HR   V  A+  SLK L LDY+DLYL+H+P+ +
Sbjct: 66  RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122



 Score = 46.0 bits (104), Expect = 7e-05
 Identities = 24/67 (35%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V KSK     + V  AI+ G+ H D+A VY  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>AB031084-1|BAA92884.1|  323|Homo sapiens bile acid-binding protein
           protein.
          Length = 323

 Score = 69.3 bits (162), Expect = 6e-12
 Identities = 30/57 (52%), Positives = 40/57 (70%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW+  HR   V  A+  SLK L LDY+DLYL+H+P+ +
Sbjct: 66  RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122



 Score = 46.0 bits (104), Expect = 7e-05
 Identities = 24/67 (35%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V KSK     + V  AI+ G+ H D+A VY  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>AB021654-1|BAA36169.1|  323|Homo sapiens DD2/bile acid-binding
           protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
           3 protein.
          Length = 323

 Score = 69.3 bits (162), Expect = 6e-12
 Identities = 30/57 (52%), Positives = 40/57 (70%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW+  HR   V  A+  SLK L LDY+DLYL+H+P+ +
Sbjct: 66  RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122



 Score = 46.0 bits (104), Expect = 7e-05
 Identities = 24/67 (35%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V KSK     + V  AI+ G+ H D+A VY  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>S68288-1|AAD14011.1|  323|Homo sapiens chlordecone reductase
           homolog protein.
          Length = 323

 Score = 68.5 bits (160), Expect = 1e-11
 Identities = 31/57 (54%), Positives = 41/57 (71%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G V+REDIF T+KLW+T HR   V  A+ +SLKK  LDY+DLYL+H P+ L
Sbjct: 66  RSKIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSL 122



 Score = 45.6 bits (103), Expect = 9e-05
 Identities = 23/67 (34%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V +SK     +V   AI+ G+RH D+A +Y  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVTKLAIEAGFRHIDSAHLYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>U05861-1|AAA18115.1|  323|Homo sapiens hepatic dihydrodiol
           dehydrogenase protein.
          Length = 323

 Score = 67.7 bits (158), Expect = 2e-11
 Identities = 30/57 (52%), Positives = 39/57 (68%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW   HR   V  A+  SLK L LDY+DLYL+H+P+ +
Sbjct: 66  RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122



 Score = 45.2 bits (102), Expect = 1e-04
 Identities = 23/67 (34%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V KSK  +   +   AI+ G+RH D+A +Y  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAE---VPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>U05684-1|AAA16227.1|  323|Homo sapiens dihydrodiol dehydrogenase
           protein.
          Length = 323

 Score = 67.7 bits (158), Expect = 2e-11
 Identities = 30/57 (52%), Positives = 39/57 (68%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW   HR   V  A+  SLK L LDY+DLYL+H+P+ +
Sbjct: 66  RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122



 Score = 45.2 bits (102), Expect = 1e-04
 Identities = 23/67 (34%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V KSK  +   +   AI+ G+RH D+A +Y  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAE---VPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>M86609-1|AAB02880.1|  323|Homo sapiens dihydrodiol dehydrogenase
           protein.
          Length = 323

 Score = 67.7 bits (158), Expect = 2e-11
 Identities = 30/57 (52%), Positives = 39/57 (68%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW   HR   V  A+  SLK L LDY+DLYL+H+P+ +
Sbjct: 66  RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122



 Score = 45.2 bits (102), Expect = 1e-04
 Identities = 23/67 (34%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V KSK  +   +   AI+ G+RH D+A +Y  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAE---VPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>L43839-1|AAB41916.1|  323|Homo sapiens 3-alpha-hydroxysteroid
           dehydrogenase protein.
          Length = 323

 Score = 67.7 bits (158), Expect = 2e-11
 Identities = 31/57 (54%), Positives = 40/57 (70%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G V REDIF T+KLW+T HR   V  A+ +SLKK  LDY+DLYL+H P+ L
Sbjct: 66  RSKIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSL 122



 Score = 45.6 bits (103), Expect = 9e-05
 Identities = 23/67 (34%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V +SK     +V   AI+ G+RH D+A +Y  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVTKLAIEAGFRHIDSAHLYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>L32592-1|AAB38486.1|  323|Homo sapiens dihydrodiol
           dehydrogenase/bile acid-binding protein protein.
          Length = 323

 Score = 67.7 bits (158), Expect = 2e-11
 Identities = 30/57 (52%), Positives = 39/57 (68%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW+  HR   V  A+  SLK L LDY DLYL+H+P+ +
Sbjct: 66  RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLIHFPVSV 122



 Score = 47.6 bits (108), Expect = 2e-05
 Identities = 25/67 (37%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V KSK     + V  AI+ GY H D+A VY  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGYHHIDSAHVYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>D26124-1|BAA05121.1|  306|Homo sapiens dihydrodiol dehydrogenase
           isoform DD1 protein.
          Length = 306

 Score = 67.7 bits (158), Expect = 2e-11
 Identities = 30/57 (52%), Positives = 39/57 (68%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW   HR   V  A+  SLK L LDY+DLYL+H+P+ +
Sbjct: 49  RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 105



 Score = 33.1 bits (72), Expect = 0.49
 Identities = 18/56 (32%), Positives = 31/56 (55%)
 Frame = +1

Query: 97  IGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIXEXVRXR 264
           +G GTY   +   V KSK  +   +   AI+ G+RH D+A +Y  E+++   +R +
Sbjct: 2   LGFGTYAPAE---VPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQVGLAIRSK 51


>BT007197-1|AAP35861.1|  323|Homo sapiens aldo-keto reductase family
           1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
           protein.
          Length = 323

 Score = 67.7 bits (158), Expect = 2e-11
 Identities = 30/57 (52%), Positives = 39/57 (68%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW   HR   V  A+  SLK L LDY+DLYL+H+P+ +
Sbjct: 66  RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122



 Score = 45.2 bits (102), Expect = 1e-04
 Identities = 23/67 (34%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V KSK  +   +   AI+ G+RH D+A +Y  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAE---VPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>BC040210-1|AAH40210.1|  323|Homo sapiens aldo-keto reductase family
           1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
           protein.
          Length = 323

 Score = 67.7 bits (158), Expect = 2e-11
 Identities = 30/57 (52%), Positives = 39/57 (68%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW   HR   V  A+  SLK L LDY+DLYL+H+P+ +
Sbjct: 66  RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122



 Score = 45.2 bits (102), Expect = 1e-04
 Identities = 23/67 (34%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V KSK  +   +   AI+ G+RH D+A +Y  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAE---VPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>BC020216-1|AAH20216.1|  323|Homo sapiens aldo-keto reductase family
           1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
           protein.
          Length = 323

 Score = 67.7 bits (158), Expect = 2e-11
 Identities = 30/57 (52%), Positives = 39/57 (68%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW   HR   V  A+  SLK L LDY+DLYL+H+P+ +
Sbjct: 66  RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122



 Score = 45.2 bits (102), Expect = 1e-04
 Identities = 23/67 (34%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V KSK  +   +   AI+ G+RH D+A +Y  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAE---VPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>BC015490-1|AAH15490.1|  323|Homo sapiens aldo-keto reductase family
           1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
           protein.
          Length = 323

 Score = 67.7 bits (158), Expect = 2e-11
 Identities = 30/57 (52%), Positives = 39/57 (68%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW   HR   V  A+  SLK L LDY+DLYL+H+P+ +
Sbjct: 66  RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122



 Score = 45.2 bits (102), Expect = 1e-04
 Identities = 23/67 (34%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V KSK  +   +   AI+ G+RH D+A +Y  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAE---VPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>AL713867-3|CAI16410.1|  247|Homo sapiens aldo-keto reductase family
           1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
           protein.
          Length = 247

 Score = 67.7 bits (158), Expect = 2e-11
 Identities = 30/57 (52%), Positives = 39/57 (68%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW   HR   V  A+  SLK L LDY+DLYL+H+P+ +
Sbjct: 32  RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 88



 Score = 29.1 bits (62), Expect = 8.0
 Identities = 11/29 (37%), Positives = 18/29 (62%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSK 150
           +K+N+G  MP +G GTY   +    ++SK
Sbjct: 6   VKLNDGHFMPVLGFGTYAPAEVGLAIRSK 34


>AL713867-2|CAI16409.1|  323|Homo sapiens aldo-keto reductase family
           1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
           protein.
          Length = 323

 Score = 67.7 bits (158), Expect = 2e-11
 Identities = 30/57 (52%), Positives = 39/57 (68%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW   HR   V  A+  SLK L LDY+DLYL+H+P+ +
Sbjct: 66  RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122



 Score = 45.2 bits (102), Expect = 1e-04
 Identities = 23/67 (34%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V KSK  +   +   AI+ G+RH D+A +Y  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAE---VPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>AB032150-1|BAA92886.1|  323|Homo sapiens 20 alph-hydroxysteroid
           dehydrogenase protein.
          Length = 323

 Score = 67.7 bits (158), Expect = 2e-11
 Identities = 30/57 (52%), Positives = 39/57 (68%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW   HR   V  A+  SLK L LDY+DLYL+H+P+ +
Sbjct: 66  RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122



 Score = 45.2 bits (102), Expect = 1e-04
 Identities = 23/67 (34%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V KSK  +   +   AI+ G+RH D+A +Y  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAE---VPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>AB031083-1|BAA92883.1|  323|Homo sapiens 20 alpha-hydroxysteroid
           dehydrogenase protein.
          Length = 323

 Score = 67.7 bits (158), Expect = 2e-11
 Identities = 30/57 (52%), Positives = 39/57 (68%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW   HR   V  A+  SLK L LDY+DLYL+H+P+ +
Sbjct: 66  RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122



 Score = 45.2 bits (102), Expect = 1e-04
 Identities = 23/67 (34%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V KSK  +   +   AI+ G+RH D+A +Y  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAE---VPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>S68287-1|AAD14010.1|  323|Homo sapiens chlordecone reductase
           protein.
          Length = 323

 Score = 67.3 bits (157), Expect = 2e-11
 Identities = 31/57 (54%), Positives = 40/57 (70%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW T  +   V  A+  SLKKL LDY+DLYL+H+P+ L
Sbjct: 66  RSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMAL 122



 Score = 40.7 bits (91), Expect = 0.002
 Identities = 20/67 (29%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +++N+G  MP +G GTY   +   V +++  +   V   AI+ G+RH D+A +Y  E+++
Sbjct: 8   VELNDGHFMPVLGFGTYAPPE---VPRNRAVE---VTKLAIEAGFRHIDSAYLYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>M33375-1|AAA35658.1|  308|Homo sapiens protein ( Human chlordecone
           reductase mRNA, complete cds. ).
          Length = 308

 Score = 67.3 bits (157), Expect = 2e-11
 Identities = 31/57 (54%), Positives = 40/57 (70%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW T  +   V  A+  SLKKL LDY+DLYL+H+P+ L
Sbjct: 51  RSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMAL 107



 Score = 35.1 bits (77), Expect = 0.12
 Identities = 18/59 (30%), Positives = 33/59 (55%)
 Frame = +1

Query: 88  MPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIXEXVRXR 264
           MP +G GTY   +   V +++  +   V   AI+ G+RH D+A +Y  E+++   +R +
Sbjct: 1   MPVLGFGTYAPPE---VPRNRAVE---VTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSK 53


>D26125-1|BAA05122.1|  321|Homo sapiens 3
           alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
           protein.
          Length = 321

 Score = 67.3 bits (157), Expect = 2e-11
 Identities = 31/57 (54%), Positives = 40/57 (70%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW T  +   V  A+  SLKKL LDY+DLYL+H+P+ L
Sbjct: 64  RSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMAL 120



 Score = 40.7 bits (91), Expect = 0.002
 Identities = 20/67 (29%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +++N+G  MP +G GTY   +   V +++  +   V   AI+ G+RH D+A +Y  E+++
Sbjct: 6   VELNDGHFMPVLGFGTYAPPE---VPRNRAVE---VTKLAIEAGFRHIDSAYLYNNEEQV 59

Query: 244 XEXVRXR 264
              +R +
Sbjct: 60  GLAIRSK 66


>BC020744-1|AAH20744.1|  323|Homo sapiens aldo-keto reductase family
           1, member C4 (chlordecone reductase; 3-alpha hydroxy
           protein.
          Length = 323

 Score = 67.3 bits (157), Expect = 2e-11
 Identities = 31/57 (54%), Positives = 40/57 (70%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW T  +   V  A+  SLKKL LDY+DLYL+H+P+ L
Sbjct: 66  RSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMAL 122



 Score = 40.7 bits (91), Expect = 0.002
 Identities = 20/67 (29%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +++N+G  MP +G GTY   +   V +++  +   V   AI+ G+RH D+A +Y  E+++
Sbjct: 8   VELNDGHFMPVLGFGTYAPPE---VPRNRAVE---VTKLAIEAGFRHIDSAYLYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>AL355303-2|CAI14202.1|  323|Homo sapiens aldo-keto reductase family
           1, member C4 (chlordecone reductase; 3-alpha hydroxy
           protein.
          Length = 323

 Score = 67.3 bits (157), Expect = 2e-11
 Identities = 31/57 (54%), Positives = 40/57 (70%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW T  +   V  A+  SLKKL LDY+DLYL+H+P+ L
Sbjct: 66  RSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMAL 122



 Score = 40.7 bits (91), Expect = 0.002
 Identities = 20/67 (29%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +++N+G  MP +G GTY   +   V +++  +   V   AI+ G+RH D+A +Y  E+++
Sbjct: 8   VELNDGHFMPVLGFGTYAPPE---VPRNRAVE---VTKLAIEAGFRHIDSAYLYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>AB045829-1|BAA99542.1|  323|Homo sapiens 3alpha-hydroxysteroid
           dehydrogenase variant protein.
          Length = 323

 Score = 67.3 bits (157), Expect = 2e-11
 Identities = 31/57 (54%), Positives = 40/57 (70%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW T  +   V  A+  SLKKL LDY+DLYL+H+P+ L
Sbjct: 66  RSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMAL 122



 Score = 40.7 bits (91), Expect = 0.002
 Identities = 20/67 (29%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +++N+G  MP +G GTY   +   V +++  +   V   AI+ G+RH D+A +Y  E+++
Sbjct: 8   VELNDGHFMPVLGFGTYAPPE---VPRNRAVE---VTKLAIEAGFRHIDSAYLYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>AB032163-1|BAA92893.1|  323|Homo sapiens dihydrodiol dehydrogenase
           4 protein.
          Length = 323

 Score = 67.3 bits (157), Expect = 2e-11
 Identities = 31/57 (54%), Positives = 40/57 (70%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW T  +   V  A+  SLKKL LDY+DLYL+H+P+ L
Sbjct: 66  RSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMAL 122



 Score = 40.7 bits (91), Expect = 0.002
 Identities = 20/67 (29%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +++N+G  MP +G GTY   +   V +++  +   V   AI+ G+RH D+A +Y  E+++
Sbjct: 8   VELNDGHFMPVLGFGTYAPPE---VPRNRAVE---VTKLAIEAGFRHIDSAYLYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>AB031085-1|BAA92885.1|  323|Homo sapiens dihydrodiol dehydrogenase
           4 protein.
          Length = 323

 Score = 67.3 bits (157), Expect = 2e-11
 Identities = 31/57 (54%), Positives = 40/57 (70%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW T  +   V  A+  SLKKL LDY+DLYL+H+P+ L
Sbjct: 66  RSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMAL 122



 Score = 40.7 bits (91), Expect = 0.002
 Identities = 20/67 (29%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +++N+G  MP +G GTY   +   V +++  +   V   AI+ G+RH D+A +Y  E+++
Sbjct: 8   VELNDGHFMPVLGFGTYAPPE---VPRNRAVE---VTKLAIEAGFRHIDSAYLYNNEEQV 61

Query: 244 XEXVRXR 264
              +R +
Sbjct: 62  GLAIRSK 68


>DQ269985-1|ABB76132.1|  323|Homo sapiens type II 3a-hydroxysteroid
           dehydrogenase variant protein.
          Length = 323

 Score = 66.5 bits (155), Expect = 4e-11
 Identities = 31/57 (54%), Positives = 38/57 (66%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW   HR   V  A+  SLKK  LDY+DLYL+H P+ L
Sbjct: 66  RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHSPMSL 122



 Score = 45.6 bits (103), Expect = 9e-05
 Identities = 24/67 (35%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V KSK  +   +   AI+ G+RH D+A +Y  E+++
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAE---VPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQV 61

Query: 244 XEXVRXR 264
              VR +
Sbjct: 62  GLAVRSK 68


>CR542203-1|CAG47000.1|  316|Homo sapiens AKR1B1 protein.
          Length = 316

 Score = 65.3 bits (152), Expect = 1e-10
 Identities = 29/54 (53%), Positives = 37/54 (68%)
 Frame = +3

Query: 261 KVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 422
           K+   VVKRE++FI +KLW T H +  V  A   +L  L LDY+DLYL+HWPIG
Sbjct: 62  KLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPIG 115



 Score = 52.4 bits (120), Expect = 8e-07
 Identities = 28/67 (41%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           L +NNG  MP +GLGT+         KS   Q+ + V  AIDVGYRH D A VY+ E E+
Sbjct: 5   LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55

Query: 244 XEXVRXR 264
              ++ +
Sbjct: 56  GVAIQEK 62


>S68290-1|AAD14012.1|  320|Homo sapiens chlordecone reductase
           homolog protein.
          Length = 320

 Score = 64.9 bits (151), Expect = 1e-10
 Identities = 29/57 (50%), Positives = 38/57 (66%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKREDIF T+KLW   HR      A+  SLK L LDY+DLYL+H+P+ +
Sbjct: 63  RSKIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHFPVSV 119



 Score = 45.2 bits (102), Expect = 1e-04
 Identities = 23/67 (34%), Positives = 39/67 (58%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           +K+N+G  MP +G GTY   +   V KSK  +   +   AI+ G+RH D+A +Y  E+++
Sbjct: 5   VKLNDGHFMPVLGFGTYAPAE---VPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQV 58

Query: 244 XEXVRXR 264
              +R +
Sbjct: 59  GLAIRSK 65


>J04794-1|AAA51711.1|  325|Homo sapiens ALDR1 protein.
          Length = 325

 Score = 64.5 bits (150), Expect = 2e-10
 Identities = 25/46 (54%), Positives = 35/46 (76%)
 Frame = +3

Query: 279 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 416
           V RE++F+T+KLWNT+H   +V  A+  +L  L L+Y+DLYLMHWP
Sbjct: 70  VPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWP 115



 Score = 47.6 bits (108), Expect = 2e-05
 Identities = 26/70 (37%), Positives = 39/70 (55%)
 Frame = +1

Query: 49  MEVPSLKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 228
           M    + ++ G+ MP IGLGT+         KS+  Q++  V  A+ VGYRH D A++Y 
Sbjct: 1   MAASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYG 51

Query: 229 TEQEIXEXVR 258
            E EI E ++
Sbjct: 52  NEPEIGEALK 61


>CR457010-1|CAG33291.1|  325|Homo sapiens AKR1A1 protein.
          Length = 325

 Score = 64.5 bits (150), Expect = 2e-10
 Identities = 25/46 (54%), Positives = 35/46 (76%)
 Frame = +3

Query: 279 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 416
           V RE++F+T+KLWNT+H   +V  A+  +L  L L+Y+DLYLMHWP
Sbjct: 70  VPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWP 115



 Score = 47.6 bits (108), Expect = 2e-05
 Identities = 26/70 (37%), Positives = 39/70 (55%)
 Frame = +1

Query: 49  MEVPSLKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 228
           M    + ++ G+ MP IGLGT+         KS+  Q++  V  A+ VGYRH D A++Y 
Sbjct: 1   MAASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYG 51

Query: 229 TEQEIXEXVR 258
            E EI E ++
Sbjct: 52  NEPEIGEALK 61


>BT007003-1|AAP35649.1|  325|Homo sapiens aldo-keto reductase family
           1, member A1 (aldehyde reductase) protein.
          Length = 325

 Score = 64.5 bits (150), Expect = 2e-10
 Identities = 25/46 (54%), Positives = 35/46 (76%)
 Frame = +3

Query: 279 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 416
           V RE++F+T+KLWNT+H   +V  A+  +L  L L+Y+DLYLMHWP
Sbjct: 70  VPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWP 115



 Score = 47.6 bits (108), Expect = 2e-05
 Identities = 26/70 (37%), Positives = 39/70 (55%)
 Frame = +1

Query: 49  MEVPSLKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 228
           M    + ++ G+ MP IGLGT+         KS+  Q++  V  A+ VGYRH D A++Y 
Sbjct: 1   MAASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYG 51

Query: 229 TEQEIXEXVR 258
            E EI E ++
Sbjct: 52  NEPEIGEALK 61


>BC005394-1|AAH05394.1|  325|Homo sapiens aldo-keto reductase family
           1, member A1 (aldehyde reductase) protein.
          Length = 325

 Score = 64.5 bits (150), Expect = 2e-10
 Identities = 25/46 (54%), Positives = 35/46 (76%)
 Frame = +3

Query: 279 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 416
           V RE++F+T+KLWNT+H   +V  A+  +L  L L+Y+DLYLMHWP
Sbjct: 70  VPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWP 115



 Score = 47.6 bits (108), Expect = 2e-05
 Identities = 26/70 (37%), Positives = 39/70 (55%)
 Frame = +1

Query: 49  MEVPSLKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 228
           M    + ++ G+ MP IGLGT+         KS+  Q++  V  A+ VGYRH D A++Y 
Sbjct: 1   MAASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYG 51

Query: 229 TEQEIXEXVR 258
            E EI E ++
Sbjct: 52  NEPEIGEALK 61


>BC000670-1|AAH00670.1|  325|Homo sapiens aldo-keto reductase family
           1, member A1 (aldehyde reductase) protein.
          Length = 325

 Score = 64.5 bits (150), Expect = 2e-10
 Identities = 25/46 (54%), Positives = 35/46 (76%)
 Frame = +3

Query: 279 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 416
           V RE++F+T+KLWNT+H   +V  A+  +L  L L+Y+DLYLMHWP
Sbjct: 70  VPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWP 115



 Score = 47.6 bits (108), Expect = 2e-05
 Identities = 26/70 (37%), Positives = 39/70 (55%)
 Frame = +1

Query: 49  MEVPSLKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 228
           M    + ++ G+ MP IGLGT+         KS+  Q++  V  A+ VGYRH D A++Y 
Sbjct: 1   MAASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYG 51

Query: 229 TEQEIXEXVR 258
            E EI E ++
Sbjct: 52  NEPEIGEALK 61


>AL355480-3|CAI22459.1|  325|Homo sapiens aldo-keto reductase family
           1, member A1 (aldehydetase, 1 protein.
          Length = 325

 Score = 64.5 bits (150), Expect = 2e-10
 Identities = 25/46 (54%), Positives = 35/46 (76%)
 Frame = +3

Query: 279 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 416
           V RE++F+T+KLWNT+H   +V  A+  +L  L L+Y+DLYLMHWP
Sbjct: 70  VPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWP 115



 Score = 47.6 bits (108), Expect = 2e-05
 Identities = 26/70 (37%), Positives = 39/70 (55%)
 Frame = +1

Query: 49  MEVPSLKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 228
           M    + ++ G+ MP IGLGT+         KS+  Q++  V  A+ VGYRH D A++Y 
Sbjct: 1   MAASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYG 51

Query: 229 TEQEIXEXVR 258
            E EI E ++
Sbjct: 52  NEPEIGEALK 61


>AL355480-2|CAI22458.1|  147|Homo sapiens aldo-keto reductase family
           1, member A1 (aldehydela) protein.
          Length = 147

 Score = 64.5 bits (150), Expect = 2e-10
 Identities = 25/46 (54%), Positives = 35/46 (76%)
 Frame = +3

Query: 279 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 416
           V RE++F+T+KLWNT+H   +V  A+  +L  L L+Y+DLYLMHWP
Sbjct: 70  VPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWP 115



 Score = 47.6 bits (108), Expect = 2e-05
 Identities = 26/70 (37%), Positives = 39/70 (55%)
 Frame = +1

Query: 49  MEVPSLKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 228
           M    + ++ G+ MP IGLGT+         KS+  Q++  V  A+ VGYRH D A++Y 
Sbjct: 1   MAASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYG 51

Query: 229 TEQEIXEXVR 258
            E EI E ++
Sbjct: 52  NEPEIGEALK 61


>AF112485-1|AAF01260.1|  325|Homo sapiens aldehyde reductase
           protein.
          Length = 325

 Score = 64.5 bits (150), Expect = 2e-10
 Identities = 25/46 (54%), Positives = 35/46 (76%)
 Frame = +3

Query: 279 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 416
           V RE++F+T+KLWNT+H   +V  A+  +L  L L+Y+DLYLMHWP
Sbjct: 70  VPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWP 115



 Score = 47.6 bits (108), Expect = 2e-05
 Identities = 26/70 (37%), Positives = 39/70 (55%)
 Frame = +1

Query: 49  MEVPSLKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 228
           M    + ++ G+ MP IGLGT+         KS+  Q++  V  A+ VGYRH D A++Y 
Sbjct: 1   MAASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYG 51

Query: 229 TEQEIXEXVR 258
            E EI E ++
Sbjct: 52  NEPEIGEALK 61


>AF036683-1|AAB92369.1|  325|Homo sapiens aldehyde reductase
           protein.
          Length = 325

 Score = 64.5 bits (150), Expect = 2e-10
 Identities = 25/46 (54%), Positives = 35/46 (76%)
 Frame = +3

Query: 279 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 416
           V RE++F+T+KLWNT+H   +V  A+  +L  L L+Y+DLYLMHWP
Sbjct: 70  VPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWP 115



 Score = 47.6 bits (108), Expect = 2e-05
 Identities = 26/70 (37%), Positives = 39/70 (55%)
 Frame = +1

Query: 49  MEVPSLKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 228
           M    + ++ G+ MP IGLGT+         KS+  Q++  V  A+ VGYRH D A++Y 
Sbjct: 1   MAASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYG 51

Query: 229 TEQEIXEXVR 258
            E EI E ++
Sbjct: 52  NEPEIGEALK 61


>X15414-1|CAA33460.1|  316|Homo sapiens protein ( Human mRNA for
           aldose reductase (EC 1.1.1.2). ).
          Length = 316

 Score = 63.3 bits (147), Expect = 4e-10
 Identities = 28/54 (51%), Positives = 36/54 (66%)
 Frame = +3

Query: 261 KVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 422
           K+   VVKRE++FI +KLW T H +  V  A   +L  L LDY+DLYL+HWP G
Sbjct: 62  KLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115



 Score = 52.4 bits (120), Expect = 8e-07
 Identities = 28/67 (41%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           L +NNG  MP +GLGT+         KS   Q+ + V  AIDVGYRH D A VY+ E E+
Sbjct: 5   LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55

Query: 244 XEXVRXR 264
              ++ +
Sbjct: 56  GVAIQEK 62


>M59783-1|AAA51712.1|  316|Homo sapiens aldose reductase protein.
          Length = 316

 Score = 63.3 bits (147), Expect = 4e-10
 Identities = 28/54 (51%), Positives = 36/54 (66%)
 Frame = +3

Query: 261 KVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 422
           K+   VVKRE++FI +KLW T H +  V  A   +L  L LDY+DLYL+HWP G
Sbjct: 62  KLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115



 Score = 52.4 bits (120), Expect = 8e-07
 Identities = 28/67 (41%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           L +NNG  MP +GLGT+         KS   Q+ + V  AIDVGYRH D A VY+ E E+
Sbjct: 5   LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55

Query: 244 XEXVRXR 264
              ++ +
Sbjct: 56  GVAIQEK 62


>M34720-1|AAA35560.1|  316|Homo sapiens protein ( Human aldose
           reductase mRNA, complete cds. ).
          Length = 316

 Score = 63.3 bits (147), Expect = 4e-10
 Identities = 28/54 (51%), Positives = 36/54 (66%)
 Frame = +3

Query: 261 KVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 422
           K+   VVKRE++FI +KLW T H +  V  A   +L  L LDY+DLYL+HWP G
Sbjct: 62  KLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115



 Score = 52.4 bits (120), Expect = 8e-07
 Identities = 28/67 (41%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           L +NNG  MP +GLGT+         KS   Q+ + V  AIDVGYRH D A VY+ E E+
Sbjct: 5   LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55

Query: 244 XEXVRXR 264
              ++ +
Sbjct: 56  GVAIQEK 62


>J05474-1|AAA51715.1|  316|Homo sapiens aldose reductase protein.
          Length = 316

 Score = 63.3 bits (147), Expect = 4e-10
 Identities = 28/54 (51%), Positives = 36/54 (66%)
 Frame = +3

Query: 261 KVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 422
           K+   VVKRE++FI +KLW T H +  V  A   +L  L LDY+DLYL+HWP G
Sbjct: 62  KLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115



 Score = 52.4 bits (120), Expect = 8e-07
 Identities = 28/67 (41%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           L +NNG  MP +GLGT+         KS   Q+ + V  AIDVGYRH D A VY+ E E+
Sbjct: 5   LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55

Query: 244 XEXVRXR 264
              ++ +
Sbjct: 56  GVAIQEK 62


>J05017-1|AAA51714.1|  316|Homo sapiens ALDR1 protein.
          Length = 316

 Score = 63.3 bits (147), Expect = 4e-10
 Identities = 28/54 (51%), Positives = 36/54 (66%)
 Frame = +3

Query: 261 KVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 422
           K+   VVKRE++FI +KLW T H +  V  A   +L  L LDY+DLYL+HWP G
Sbjct: 62  KLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115



 Score = 51.6 bits (118), Expect = 1e-06
 Identities = 27/65 (41%), Positives = 37/65 (56%)
 Frame = +1

Query: 70  MNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIXE 249
           +NNG  MP +GLGT+         KS   Q+ + V  AIDVGYRH D A VY+ E E+  
Sbjct: 7   LNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGV 57

Query: 250 XVRXR 264
            ++ +
Sbjct: 58  AIQEK 62


>J04795-1|AAA51713.1|  316|Homo sapiens ALDR1 protein.
          Length = 316

 Score = 63.3 bits (147), Expect = 4e-10
 Identities = 28/54 (51%), Positives = 36/54 (66%)
 Frame = +3

Query: 261 KVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 422
           K+   VVKRE++FI +KLW T H +  V  A   +L  L LDY+DLYL+HWP G
Sbjct: 62  KLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115



 Score = 52.4 bits (120), Expect = 8e-07
 Identities = 28/67 (41%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           L +NNG  MP +GLGT+         KS   Q+ + V  AIDVGYRH D A VY+ E E+
Sbjct: 5   LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55

Query: 244 XEXVRXR 264
              ++ +
Sbjct: 56  GVAIQEK 62


>CR450351-1|CAG29347.1|  316|Homo sapiens AKR1B1 protein.
          Length = 316

 Score = 63.3 bits (147), Expect = 4e-10
 Identities = 28/54 (51%), Positives = 36/54 (66%)
 Frame = +3

Query: 261 KVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 422
           K+   VVKRE++FI +KLW T H +  V  A   +L  L LDY+DLYL+HWP G
Sbjct: 62  KLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115



 Score = 52.4 bits (120), Expect = 8e-07
 Identities = 28/67 (41%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           L +NNG  MP +GLGT+         KS   Q+ + V  AIDVGYRH D A VY+ E E+
Sbjct: 5   LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55

Query: 244 XEXVRXR 264
              ++ +
Sbjct: 56  GVAIQEK 62


>BT019859-1|AAV38662.1|  316|Homo sapiens aldo-keto reductase family
           1, member B1 (aldose reductase) protein.
          Length = 316

 Score = 63.3 bits (147), Expect = 4e-10
 Identities = 28/54 (51%), Positives = 36/54 (66%)
 Frame = +3

Query: 261 KVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 422
           K+   VVKRE++FI +KLW T H +  V  A   +L  L LDY+DLYL+HWP G
Sbjct: 62  KLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115



 Score = 52.4 bits (120), Expect = 8e-07
 Identities = 28/67 (41%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           L +NNG  MP +GLGT+         KS   Q+ + V  AIDVGYRH D A VY+ E E+
Sbjct: 5   LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55

Query: 244 XEXVRXR 264
              ++ +
Sbjct: 56  GVAIQEK 62


>BC010391-1|AAH10391.1|  316|Homo sapiens aldo-keto reductase family
           1, member B1 (aldose reductase) protein.
          Length = 316

 Score = 63.3 bits (147), Expect = 4e-10
 Identities = 28/54 (51%), Positives = 36/54 (66%)
 Frame = +3

Query: 261 KVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 422
           K+   VVKRE++FI +KLW T H +  V  A   +L  L LDY+DLYL+HWP G
Sbjct: 62  KLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115



 Score = 52.4 bits (120), Expect = 8e-07
 Identities = 28/67 (41%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           L +NNG  MP +GLGT+         KS   Q+ + V  AIDVGYRH D A VY+ E E+
Sbjct: 5   LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55

Query: 244 XEXVRXR 264
              ++ +
Sbjct: 56  GVAIQEK 62


>BC005387-1|AAH05387.1|  316|Homo sapiens aldo-keto reductase family
           1, member B1 (aldose reductase) protein.
          Length = 316

 Score = 63.3 bits (147), Expect = 4e-10
 Identities = 28/54 (51%), Positives = 36/54 (66%)
 Frame = +3

Query: 261 KVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 422
           K+   VVKRE++FI +KLW T H +  V  A   +L  L LDY+DLYL+HWP G
Sbjct: 62  KLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115



 Score = 52.4 bits (120), Expect = 8e-07
 Identities = 28/67 (41%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           L +NNG  MP +GLGT+         KS   Q+ + V  AIDVGYRH D A VY+ E E+
Sbjct: 5   LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55

Query: 244 XEXVRXR 264
              ++ +
Sbjct: 56  GVAIQEK 62


>BC000260-1|AAH00260.1|  316|Homo sapiens aldo-keto reductase family
           1, member B1 (aldose reductase) protein.
          Length = 316

 Score = 63.3 bits (147), Expect = 4e-10
 Identities = 28/54 (51%), Positives = 36/54 (66%)
 Frame = +3

Query: 261 KVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 422
           K+   VVKRE++FI +KLW T H +  V  A   +L  L LDY+DLYL+HWP G
Sbjct: 62  KLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115



 Score = 52.4 bits (120), Expect = 8e-07
 Identities = 28/67 (41%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           L +NNG  MP +GLGT+         KS   Q+ + V  AIDVGYRH D A VY+ E E+
Sbjct: 5   LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55

Query: 244 XEXVRXR 264
              ++ +
Sbjct: 56  GVAIQEK 62


>AF328729-1|AAN09721.1|  316|Homo sapiens CTCL tumor antigen
           HD-CL-07 protein.
          Length = 316

 Score = 63.3 bits (147), Expect = 4e-10
 Identities = 28/54 (51%), Positives = 36/54 (66%)
 Frame = +3

Query: 261 KVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 422
           K+   VVKRE++FI +KLW T H +  V  A   +L  L LDY+DLYL+HWP G
Sbjct: 62  KLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115



 Score = 52.4 bits (120), Expect = 8e-07
 Identities = 28/67 (41%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           L +NNG  MP +GLGT+         KS   Q+ + V  AIDVGYRH D A VY+ E E+
Sbjct: 5   LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55

Query: 244 XEXVRXR 264
              ++ +
Sbjct: 56  GVAIQEK 62


>AF032455-1|AAB88851.1|  316|Homo sapiens aldose reductase protein.
          Length = 316

 Score = 63.3 bits (147), Expect = 4e-10
 Identities = 28/54 (51%), Positives = 36/54 (66%)
 Frame = +3

Query: 261 KVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 422
           K+   VVKRE++FI +KLW T H +  V  A   +L  L LDY+DLYL+HWP G
Sbjct: 62  KLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115



 Score = 52.4 bits (120), Expect = 8e-07
 Identities = 28/67 (41%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           L +NNG  MP +GLGT+         KS   Q+ + V  AIDVGYRH D A VY+ E E+
Sbjct: 5   LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55

Query: 244 XEXVRXR 264
              ++ +
Sbjct: 56  GVAIQEK 62


>AB209796-1|BAD93033.1|  260|Homo sapiens aldo-keto reductase family
           1, member B1 variant protein.
          Length = 260

 Score = 63.3 bits (147), Expect = 4e-10
 Identities = 28/54 (51%), Positives = 36/54 (66%)
 Frame = +3

Query: 261 KVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 422
           K+   VVKRE++FI +KLW T H +  V  A   +L  L LDY+DLYL+HWP G
Sbjct: 59  KLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 112



 Score = 52.4 bits (120), Expect = 8e-07
 Identities = 28/67 (41%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           L +NNG  MP +GLGT+         KS   Q+ + V  AIDVGYRH D A VY+ E E+
Sbjct: 2   LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 52

Query: 244 XEXVRXR 264
              ++ +
Sbjct: 53  GVAIQEK 59


>AB037902-1|BAA92887.1|  130|Homo sapiens truncated aldo-keto
           reductase protein.
          Length = 130

 Score = 63.3 bits (147), Expect = 4e-10
 Identities = 29/57 (50%), Positives = 38/57 (66%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           + K+  G VKR+DIF TTK+W T  R   V + +  SLKKL L Y+DLYL H+P+ L
Sbjct: 67  RKKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPL 123



 Score = 46.0 bits (104), Expect = 7e-05
 Identities = 24/68 (35%), Positives = 38/68 (55%)
 Frame = +1

Query: 61  SLKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 240
           S+K+N+G+ MP +G GT +        K     + + V  AIDVGYRH D+A  +  E+ 
Sbjct: 8   SVKLNDGKFMPILGFGTSVAR------KVAMSNVEEAVQVAIDVGYRHIDSAYTHLNEEG 61

Query: 241 IXEXVRXR 264
           I + +R +
Sbjct: 62  IGQAIRKK 69


>U37100-1|AAC17469.1|  316|Homo sapiens aldose reductase-like
           peptide protein.
          Length = 316

 Score = 61.3 bits (142), Expect = 2e-09
 Identities = 27/57 (47%), Positives = 36/57 (63%)
 Frame = +3

Query: 261 KVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA 431
           K+    VKRED+FI +KLW T   R  V +A   +LK L L Y+D+YL+HWP G  +
Sbjct: 62  KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKS 118



 Score = 44.4 bits (100), Expect = 2e-04
 Identities = 23/67 (34%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           ++++    MP +GLGT+         KS   ++++ V  AID GYRH D A VY+ E E+
Sbjct: 5   VELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55

Query: 244 XEXVRXR 264
            E ++ +
Sbjct: 56  GEAIQEK 62


>CR541801-1|CAG46600.1|  316|Homo sapiens AKR1B10 protein.
          Length = 316

 Score = 61.3 bits (142), Expect = 2e-09
 Identities = 27/57 (47%), Positives = 36/57 (63%)
 Frame = +3

Query: 261 KVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA 431
           K+    VKRED+FI +KLW T   R  V +A   +LK L L Y+D+YL+HWP G  +
Sbjct: 62  KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKS 118



 Score = 44.4 bits (100), Expect = 2e-04
 Identities = 23/67 (34%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           ++++    MP +GLGT+         KS   ++++ V  AID GYRH D A VY+ E E+
Sbjct: 5   VELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55

Query: 244 XEXVRXR 264
            E ++ +
Sbjct: 56  GEAIQEK 62


>BT006794-1|AAP35440.1|  316|Homo sapiens aldo-keto reductase family
           1, member B10 (aldose reductase) protein.
          Length = 316

 Score = 61.3 bits (142), Expect = 2e-09
 Identities = 27/57 (47%), Positives = 36/57 (63%)
 Frame = +3

Query: 261 KVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA 431
           K+    VKRED+FI +KLW T   R  V +A   +LK L L Y+D+YL+HWP G  +
Sbjct: 62  KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKS 118



 Score = 44.4 bits (100), Expect = 2e-04
 Identities = 23/67 (34%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           ++++    MP +GLGT+         KS   ++++ V  AID GYRH D A VY+ E E+
Sbjct: 5   VELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55

Query: 244 XEXVRXR 264
            E ++ +
Sbjct: 56  GEAIQEK 62


>BC008837-1|AAH08837.1|  316|Homo sapiens aldo-keto reductase family
           1, member B10 (aldose reductase) protein.
          Length = 316

 Score = 61.3 bits (142), Expect = 2e-09
 Identities = 27/57 (47%), Positives = 36/57 (63%)
 Frame = +3

Query: 261 KVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA 431
           K+    VKRED+FI +KLW T   R  V +A   +LK L L Y+D+YL+HWP G  +
Sbjct: 62  KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKS 118



 Score = 44.4 bits (100), Expect = 2e-04
 Identities = 23/67 (34%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           ++++    MP +GLGT+         KS   ++++ V  AID GYRH D A VY+ E E+
Sbjct: 5   VELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55

Query: 244 XEXVRXR 264
            E ++ +
Sbjct: 56  GEAIQEK 62


>AF052577-1|AAC36465.1|  316|Homo sapiens aldo-keto reductase
           protein.
          Length = 316

 Score = 61.3 bits (142), Expect = 2e-09
 Identities = 27/57 (47%), Positives = 36/57 (63%)
 Frame = +3

Query: 261 KVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA 431
           K+    VKRED+FI +KLW T   R  V +A   +LK L L Y+D+YL+HWP G  +
Sbjct: 62  KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKS 118



 Score = 44.4 bits (100), Expect = 2e-04
 Identities = 23/67 (34%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           ++++    MP +GLGT+         KS   ++++ V  AID GYRH D A VY+ E E+
Sbjct: 5   VELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55

Query: 244 XEXVRXR 264
            E ++ +
Sbjct: 56  GEAIQEK 62


>BC101205-1|AAI01206.1|  129|Homo sapiens aldo-keto reductase family
           1, member C-like 1 protein.
          Length = 129

 Score = 60.9 bits (141), Expect = 2e-09
 Identities = 28/55 (50%), Positives = 36/55 (65%)
 Frame = +3

Query: 261 KVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           K+  G VKRE+IF T KLW T  R   V  A+  SLKKLG DY+DL+++H P  +
Sbjct: 71  KIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAM 125



 Score = 47.2 bits (107), Expect = 3e-05
 Identities = 24/65 (36%), Positives = 40/65 (61%)
 Frame = +1

Query: 61  SLKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 240
           S+++N+G  MP +G GTY     +   KS+  +   V   AIDVG+RH D+A +Y+ E+E
Sbjct: 10  SVRLNDGPFMPVLGFGTYA---PDHTPKSQAAEATKV---AIDVGFRHIDSAYLYQNEEE 63

Query: 241 IXEXV 255
           + + +
Sbjct: 64  VGQAI 68


>BC101204-1|AAI01205.1|  129|Homo sapiens aldo-keto reductase family
           1, member C-like 1 protein.
          Length = 129

 Score = 60.9 bits (141), Expect = 2e-09
 Identities = 28/55 (50%), Positives = 36/55 (65%)
 Frame = +3

Query: 261 KVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           K+  G VKRE+IF T KLW T  R   V  A+  SLKKLG DY+DL+++H P  +
Sbjct: 71  KIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAM 125



 Score = 47.2 bits (107), Expect = 3e-05
 Identities = 24/65 (36%), Positives = 40/65 (61%)
 Frame = +1

Query: 61  SLKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 240
           S+++N+G  MP +G GTY     +   KS+  +   V   AIDVG+RH D+A +Y+ E+E
Sbjct: 10  SVRLNDGPFMPVLGFGTYA---PDHTPKSQAAEATKV---AIDVGFRHIDSAYLYQNEEE 63

Query: 241 IXEXV 255
           + + +
Sbjct: 64  VGQAI 68


>AL391427-2|CAI14727.1|  302|Homo sapiens aldo-keto reductase family
           1, member C-like 1 protein.
          Length = 302

 Score = 60.9 bits (141), Expect = 2e-09
 Identities = 28/55 (50%), Positives = 36/55 (65%)
 Frame = +3

Query: 261 KVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           K+  G VKRE+IF T KLW T  R   V  A+  SLKKLG DY+DL+++H P  +
Sbjct: 71  KIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAM 125



 Score = 47.2 bits (107), Expect = 3e-05
 Identities = 24/65 (36%), Positives = 40/65 (61%)
 Frame = +1

Query: 61  SLKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 240
           S+++N+G  MP +G GTY     +   KS+  +   V   AIDVG+RH D+A +Y+ E+E
Sbjct: 10  SVRLNDGPFMPVLGFGTYA---PDHTPKSQAAEATKV---AIDVGFRHIDSAYLYQNEEE 63

Query: 241 IXEXV 255
           + + +
Sbjct: 64  VGQAI 68


>AL355303-1|CAI14201.1|  302|Homo sapiens aldo-keto reductase family
           1, member C-like 1 protein.
          Length = 302

 Score = 60.9 bits (141), Expect = 2e-09
 Identities = 28/55 (50%), Positives = 36/55 (65%)
 Frame = +3

Query: 261 KVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           K+  G VKRE+IF T KLW T  R   V  A+  SLKKLG DY+DL+++H P  +
Sbjct: 71  KIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAM 125



 Score = 47.2 bits (107), Expect = 3e-05
 Identities = 24/65 (36%), Positives = 40/65 (61%)
 Frame = +1

Query: 61  SLKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 240
           S+++N+G  MP +G GTY     +   KS+  +   V   AIDVG+RH D+A +Y+ E+E
Sbjct: 10  SVRLNDGPFMPVLGFGTYA---PDHTPKSQAAEATKV---AIDVGFRHIDSAYLYQNEEE 63

Query: 241 IXEXV 255
           + + +
Sbjct: 64  VGQAI 68


>AK131335-1|BAD18494.1|  129|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16347 fis, clone TESTI2036288, moderately
           similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
          Length = 129

 Score = 60.9 bits (141), Expect = 2e-09
 Identities = 28/55 (50%), Positives = 36/55 (65%)
 Frame = +3

Query: 261 KVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           K+  G VKRE+IF T KLW T  R   V  A+  SLKKLG DY+DL+++H P  +
Sbjct: 71  KIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAM 125



 Score = 47.2 bits (107), Expect = 3e-05
 Identities = 24/65 (36%), Positives = 40/65 (61%)
 Frame = +1

Query: 61  SLKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 240
           S+++N+G  MP +G GTY     +   KS+  +   V   AIDVG+RH D+A +Y+ E+E
Sbjct: 10  SVRLNDGPFMPVLGFGTYA---PDHTPKSQAAEATKV---AIDVGFRHIDSAYLYQNEEE 63

Query: 241 IXEXV 255
           + + +
Sbjct: 64  VGQAI 68


>AF524864-1|AAO13380.1|  316|Homo sapiens aldo-ketoreductase
           protein.
          Length = 316

 Score = 58.4 bits (135), Expect = 1e-08
 Identities = 26/57 (45%), Positives = 35/57 (61%)
 Frame = +3

Query: 261 KVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA 431
           K+    VKRED+FI +KLW T   R  V +A   +LK   L Y+D+YL+HWP G  +
Sbjct: 62  KIQEKAVKREDLFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQGFKS 118



 Score = 44.4 bits (100), Expect = 2e-04
 Identities = 23/67 (34%), Positives = 38/67 (56%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 243
           ++++    MP +GLGT+         KS   ++++ V  AID GYRH D A VY+ E E+
Sbjct: 5   VELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55

Query: 244 XEXVRXR 264
            E ++ +
Sbjct: 56  GEAIQEK 62


>Z28339-1|CAA82193.1|  326|Homo sapiens delta 4-3-oxosteroid 5
           beta-reductase protein.
          Length = 326

 Score = 50.8 bits (116), Expect = 2e-06
 Identities = 23/55 (41%), Positives = 33/55 (60%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 419
           + K+  G V+REDIF   KLW T H    V   +  +L+ L LDY+DLY++  P+
Sbjct: 69  REKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPM 123



 Score = 45.6 bits (103), Expect = 9e-05
 Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 1/68 (1%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDK-QLRDVVMRAIDVGYRHFDTASVYETEQE 240
           + +++G  +P IGLGTY         KS  K      V  AID GYRH D A +Y+ E E
Sbjct: 10  IPLSDGNSIPIIGLGTY------SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHE 63

Query: 241 IXEXVRXR 264
           + E +R +
Sbjct: 64  VGEAIREK 71


>BC130627-1|AAI30628.1|  326|Homo sapiens aldo-keto reductase family
           1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
           protein.
          Length = 326

 Score = 50.8 bits (116), Expect = 2e-06
 Identities = 23/55 (41%), Positives = 33/55 (60%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 419
           + K+  G V+REDIF   KLW T H    V   +  +L+ L LDY+DLY++  P+
Sbjct: 69  REKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPM 123



 Score = 45.6 bits (103), Expect = 9e-05
 Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 1/68 (1%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDK-QLRDVVMRAIDVGYRHFDTASVYETEQE 240
           + +++G  +P IGLGTY         KS  K      V  AID GYRH D A +Y+ E E
Sbjct: 10  IPLSDGNSIPIIGLGTY------SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHE 63

Query: 241 IXEXVRXR 264
           + E +R +
Sbjct: 64  VGEAIREK 71


>BC130625-1|AAI30626.1|  326|Homo sapiens aldo-keto reductase family
           1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
           protein.
          Length = 326

 Score = 50.8 bits (116), Expect = 2e-06
 Identities = 23/55 (41%), Positives = 33/55 (60%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 419
           + K+  G V+REDIF   KLW T H    V   +  +L+ L LDY+DLY++  P+
Sbjct: 69  REKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPM 123



 Score = 45.6 bits (103), Expect = 9e-05
 Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 1/68 (1%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDK-QLRDVVMRAIDVGYRHFDTASVYETEQE 240
           + +++G  +P IGLGTY         KS  K      V  AID GYRH D A +Y+ E E
Sbjct: 10  IPLSDGNSIPIIGLGTY------SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHE 63

Query: 241 IXEXVRXR 264
           + E +R +
Sbjct: 64  VGEAIREK 71


>AF283659-1|AAG39381.1|  326|Homo sapiens 5-beta steroid reductase
           protein.
          Length = 326

 Score = 50.8 bits (116), Expect = 2e-06
 Identities = 23/55 (41%), Positives = 33/55 (60%)
 Frame = +3

Query: 255 KXKVXXGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 419
           + K+  G V+REDIF   KLW T H    V   +  +L+ L LDY+DLY++  P+
Sbjct: 69  REKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPM 123



 Score = 45.6 bits (103), Expect = 9e-05
 Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 1/68 (1%)
 Frame = +1

Query: 64  LKMNNGRDMPAIGLGTYLGXDQNGVVKSKDK-QLRDVVMRAIDVGYRHFDTASVYETEQE 240
           + +++G  +P IGLGTY         KS  K      V  AID GYRH D A +Y+ E E
Sbjct: 10  IPLSDGNSIPIIGLGTY------SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHE 63

Query: 241 IXEXVRXR 264
           + E +R +
Sbjct: 64  VGEAIREK 71


>AB037905-2|BAA92890.1|   45|Homo sapiens truncated aldo-keto
           reductase protein.
          Length = 45

 Score = 39.9 bits (89), Expect = 0.004
 Identities = 18/38 (47%), Positives = 24/38 (63%)
 Frame = +3

Query: 312 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 425
           +W T  R   V + +  SLKKL L Y+DLYL H+P+ L
Sbjct: 1   VWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPL 38


>AK125347-1|BAC86140.1|  277|Homo sapiens protein ( Homo sapiens
           cDNA FLJ43357 fis, clone NT2RP7013795, weakly  similar
           to VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
          Length = 277

 Score = 29.5 bits (63), Expect = 6.1
 Identities = 18/49 (36%), Positives = 23/49 (46%)
 Frame = -3

Query: 163 GAACPWTSLRRSDQXQGTCPGRWRACLCRCSFLTRALPSLTPAQAPTGT 17
           G+  P   LR     +G+   RW A    CS    A P  TPAQ P+G+
Sbjct: 171 GSEVPRGPLRPRAASRGSSATRWAAPPRPCSRPDPAGPLQTPAQTPSGS 219


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 60,257,130
Number of Sequences: 237096
Number of extensions: 1030701
Number of successful extensions: 2154
Number of sequences better than 10.0: 92
Number of HSP's better than 10.0 without gapping: 1951
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2090
length of database: 76,859,062
effective HSP length: 84
effective length of database: 56,942,998
effective search space used: 4042952858
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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