BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= e96h0127 (700 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q9VH08 Cluster: CG6284-PA; n=9; Eumetazoa|Rep: CG6284-P... 132 8e-30 UniRef50_Q8N6T7-2 Cluster: Isoform 2 of Q8N6T7 ; n=5; Catarrhini... 101 1e-20 UniRef50_Q8N6T7 Cluster: Mono-ADP-ribosyltransferase sirtuin-6; ... 101 1e-20 UniRef50_Q9FE17 Cluster: Sir2-like protein; n=9; Magnoliophyta|R... 89 1e-16 UniRef50_Q7SB01 Cluster: Putative uncharacterized protein NCU076... 81 3e-14 UniRef50_Q4UH74 Cluster: Sir2-like histone deacetylase, putative... 78 2e-13 UniRef50_A5K3P4 Cluster: Putative uncharacterized protein; n=1; ... 78 2e-13 UniRef50_A5AF92 Cluster: Putative uncharacterized protein; n=1; ... 77 4e-13 UniRef50_Q7RP35 Cluster: Sir2-like protein; n=5; Plasmodium (Vin... 77 6e-13 UniRef50_UPI0000D573CE Cluster: PREDICTED: similar to CG11305-PA... 75 2e-12 UniRef50_Q1MT39 Cluster: Novel protein similar to vertebratesirt... 73 7e-12 UniRef50_A7AWG1 Cluster: Transcriptional regulator, Sir2 family ... 73 7e-12 UniRef50_Q8N6T7-3 Cluster: Isoform 3 of Q8N6T7 ; n=2; Catarrhini... 71 2e-11 UniRef50_Q8IKW2 Cluster: Putative uncharacterized protein; n=1; ... 71 2e-11 UniRef50_Q9NRC8 Cluster: NAD-dependent deacetylase sirtuin-7; n=... 71 2e-11 UniRef50_Q175I4 Cluster: Chromatin regulatory protein sir2; n=3;... 69 1e-10 UniRef50_UPI00015B56BB Cluster: PREDICTED: similar to ENSANGP000... 64 3e-09 UniRef50_Q9VAQ1 Cluster: CG11305-PA; n=8; Coelomata|Rep: CG11305... 62 2e-08 UniRef50_Q29QS4 Cluster: IP11347p; n=1; Drosophila melanogaster|... 61 2e-08 UniRef50_UPI000049979A Cluster: Sir2 family transcriptional regu... 57 4e-07 UniRef50_Q22KA8 Cluster: Transcriptional regulator, Sir2 family ... 56 8e-07 UniRef50_Q3F1F4 Cluster: SIR2 family protein; n=1; Bacillus thur... 55 2e-06 UniRef50_A6DC77 Cluster: Silent information regulator protein Si... 55 2e-06 UniRef50_A4M603 Cluster: Silent information regulator protein Si... 53 8e-06 UniRef50_Q974M6 Cluster: NAD-dependent deacetylase; n=8; Thermop... 53 8e-06 UniRef50_A3ZMQ7 Cluster: Sir2 family, possible ADP ribosyltransf... 52 1e-05 UniRef50_Q89LY4 Cluster: NAD-dependent deacetylase 1; n=12; Prot... 52 1e-05 UniRef50_Q95Q89 Cluster: Yeast sir related protein 2.4; n=2; Cae... 51 2e-05 UniRef50_Q8ZT00 Cluster: NAD-dependent deacetylase 2; n=2; cellu... 51 3e-05 UniRef50_Q3A6W7 Cluster: NAD-dependent protein deacetylases, SIR... 50 4e-05 UniRef50_Q54GV7 Cluster: NAD(+)-dependent deacetylase, silent in... 50 5e-05 UniRef50_A7EMW8 Cluster: Putative uncharacterized protein; n=1; ... 50 7e-05 UniRef50_UPI00006CB0CC Cluster: transcriptional regulator, Sir2 ... 49 1e-04 UniRef50_UPI000049971A Cluster: Sir2 family transcriptional regu... 49 1e-04 UniRef50_Q5YR82 Cluster: Putative Sir2 family regulator; n=1; No... 49 1e-04 UniRef50_Q0AY57 Cluster: Regulatory protein, sir2 family; n=1; S... 49 1e-04 UniRef50_UPI00015B57C0 Cluster: PREDICTED: similar to GA18743-PA... 49 1e-04 UniRef50_Q9WYW0 Cluster: NAD-dependent deacetylase; n=4; Thermot... 49 1e-04 UniRef50_Q8ZU41 Cluster: NAD-dependent deacetylase 1; n=3; Pyrob... 49 1e-04 UniRef50_Q2LSF2 Cluster: Sir2 family of NAD+-dependent deacetyla... 48 2e-04 UniRef50_Q8CJM9 Cluster: NAD-dependent deacetylase 2; n=3; Actin... 48 2e-04 UniRef50_Q2YZT2 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04 UniRef50_A7B9E8 Cluster: Putative uncharacterized protein; n=1; ... 48 3e-04 UniRef50_A6RRE3 Cluster: Putative uncharacterized protein; n=1; ... 48 3e-04 UniRef50_Q5KZE8 Cluster: NAD-dependent deacetylase 2; n=3; Bacte... 48 3e-04 UniRef50_UPI0000E49846 Cluster: PREDICTED: similar to Sirtuin (s... 47 4e-04 UniRef50_Q5KA61 Cluster: Histone deacetylase, putative; n=1; Fil... 47 4e-04 UniRef50_A6R1B0 Cluster: Predicted protein; n=2; Onygenales|Rep:... 47 4e-04 UniRef50_A2Q9C4 Cluster: Contig An01c0250, complete genome; n=18... 47 4e-04 UniRef50_O96505 Cluster: SIR2; n=4; Sophophora|Rep: SIR2 - Droso... 47 5e-04 UniRef50_Q5AQ47 Cluster: Potential Sir2 family histone deacetyla... 47 5e-04 UniRef50_Q8REC3 Cluster: NAD-dependent deacetylase; n=3; Fusobac... 47 5e-04 UniRef50_Q8R984 Cluster: NAD-dependent deacetylase 2; n=1; Therm... 47 5e-04 UniRef50_Q23A43 Cluster: Transcriptional regulator, Sir2 family ... 46 7e-04 UniRef50_Q1RPU3 Cluster: Zinc finger protein; n=1; Ciona intesti... 46 7e-04 UniRef50_A7DQD6 Cluster: Silent information regulator protein Si... 46 7e-04 UniRef50_Q21921 Cluster: NAD-dependent deacetylase SIR2 homolog;... 46 7e-04 UniRef50_O07595 Cluster: NAD-dependent deacetylase; n=3; Bacillu... 46 7e-04 UniRef50_A6TNA0 Cluster: Silent information regulator protein Si... 46 9e-04 UniRef50_A6G0H3 Cluster: Silent information regulator protein Si... 46 9e-04 UniRef50_A0NQ49 Cluster: Silent information regulator protein Si... 46 9e-04 UniRef50_Q2GZ88 Cluster: Putative uncharacterized protein; n=1; ... 46 9e-04 UniRef50_A6PTK3 Cluster: Silent information regulator protein Si... 46 0.001 UniRef50_A5UYK2 Cluster: Silent information regulator protein Si... 46 0.001 UniRef50_Q5BVF7 Cluster: SJCHGC03105 protein; n=2; Schistosoma j... 46 0.001 UniRef50_Q12Y78 Cluster: Silent information regulator protein Si... 46 0.001 UniRef50_Q73KE1 Cluster: NAD-dependent deacetylase; n=1; Trepone... 46 0.001 UniRef50_A6P1S7 Cluster: Putative uncharacterized protein; n=2; ... 45 0.002 UniRef50_A0LG97 Cluster: Silent information regulator protein Si... 45 0.002 UniRef50_Q9FY91 Cluster: SIR2-family protein; n=12; Magnoliophyt... 45 0.002 UniRef50_A7SX90 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 45 0.002 UniRef50_A7EC18 Cluster: Putative uncharacterized protein; n=1; ... 45 0.002 UniRef50_Q8CNF4 Cluster: NAD-dependent deacetylase; n=17; Staphy... 45 0.002 UniRef50_UPI0000D55B5A Cluster: PREDICTED: similar to CG5216-PA;... 45 0.002 UniRef50_UPI000051AA14 Cluster: PREDICTED: similar to NAD-depend... 45 0.002 UniRef50_Q23E36 Cluster: Transcriptional regulator, Sir2 family ... 45 0.002 UniRef50_A2F8E1 Cluster: Transcriptional regulator, Sir2 family ... 45 0.002 UniRef50_Q7S386 Cluster: Putative uncharacterized protein NCU048... 45 0.002 UniRef50_Q6CB00 Cluster: Similarities with tr|Q9UR39 Schizosacch... 45 0.002 UniRef50_Q0CR31 Cluster: NAD-dependent histone deacetylase SIR2;... 45 0.002 UniRef50_A6RSV6 Cluster: Putative uncharacterized protein; n=2; ... 45 0.002 UniRef50_Q0LIC7 Cluster: Silent information regulator protein Si... 44 0.003 UniRef50_A6DES9 Cluster: Transcriptional regulator, Sir2 family ... 44 0.003 UniRef50_Q6CQA7 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 44 0.003 UniRef50_Q0UNC9 Cluster: Putative uncharacterized protein; n=1; ... 44 0.003 UniRef50_A6RXY5 Cluster: Putative uncharacterized protein; n=2; ... 44 0.003 UniRef50_A1DG07 Cluster: SIR2 family histone deacetylase, putati... 44 0.003 UniRef50_Q88ZA0 Cluster: NAD-dependent deacetylase; n=4; Lactoba... 44 0.003 UniRef50_UPI000023F1DF Cluster: hypothetical protein FG02466.1; ... 44 0.004 UniRef50_A7HL19 Cluster: Silent information regulator protein Si... 44 0.004 UniRef50_A4JS80 Cluster: Silent information regulator protein Si... 44 0.004 UniRef50_Q875P9 Cluster: HST1; n=1; Lachancea kluyveri|Rep: HST1... 44 0.004 UniRef50_Q7S6G9 Cluster: Putative uncharacterized protein NCU047... 44 0.004 UniRef50_Q6C8V5 Cluster: Similar to tr|Q9FY91 Arabidopsis thalia... 44 0.004 UniRef50_Q4WT50 Cluster: SIR2 family histone deacetylase (Hst4),... 44 0.004 UniRef50_Q5L014 Cluster: NAD-dependent deacetylase 1; n=7; Bacil... 44 0.004 UniRef50_A1ZPG8 Cluster: NAD-dependent deacetylase; n=1; Microsc... 44 0.005 UniRef50_Q7SCL4 Cluster: Putative uncharacterized protein NCU005... 44 0.005 UniRef50_A1HLU5 Cluster: Silent information regulator protein Si... 43 0.006 UniRef50_A7TQE2 Cluster: Putative uncharacterized protein; n=1; ... 43 0.006 UniRef50_A2QFF9 Cluster: Complex: Sir2p is one of four Silent In... 43 0.006 UniRef50_Q5V4Q5 Cluster: NAD-dependent deacetylase; n=2; Halobac... 43 0.006 UniRef50_Q011Q8 Cluster: NAD-dependent deacetylase SIRT2; n=2; O... 43 0.008 UniRef50_Q6BPH5 Cluster: Debaryomyces hansenii chromosome E of s... 43 0.008 UniRef50_Q0UMU7 Cluster: Putative uncharacterized protein; n=1; ... 43 0.008 UniRef50_O94066 Cluster: Transcription regulatory protein; n=6; ... 43 0.008 UniRef50_Q96EB6 Cluster: NAD-dependent deacetylase sirtuin-1; n=... 43 0.008 UniRef50_Q9UR39 Cluster: NAD-dependent deacetylase hst4; n=1; Sc... 43 0.008 UniRef50_A4J646 Cluster: Silent information regulator protein Si... 42 0.011 UniRef50_A1HU63 Cluster: Silent information regulator protein Si... 42 0.011 UniRef50_A7RMK8 Cluster: Predicted protein; n=5; Eumetazoa|Rep: ... 42 0.011 UniRef50_A0D0F1 Cluster: Chromosome undetermined scaffold_33, wh... 42 0.011 UniRef50_Q6BPA4 Cluster: Debaryomyces hansenii chromosome E of s... 42 0.011 UniRef50_A5DSX8 Cluster: NAD-dependent histone deacetylase SIR2;... 42 0.011 UniRef50_A4RMS1 Cluster: Putative uncharacterized protein; n=2; ... 42 0.011 UniRef50_Q5KPC9 Cluster: Hst3 protein, putative; n=2; Filobasidi... 42 0.015 UniRef50_Q4PG00 Cluster: Putative uncharacterized protein; n=1; ... 42 0.015 UniRef50_A5DNV7 Cluster: Putative uncharacterized protein; n=1; ... 42 0.015 UniRef50_Q9NXA8 Cluster: NAD-dependent deacetylase sirtuin-5; n=... 42 0.015 UniRef50_Q97MB4 Cluster: NAD-dependent deacetylase; n=7; Bacteri... 42 0.015 UniRef50_A6Q2C0 Cluster: Transcriptional regulator, Sir2 family;... 42 0.019 UniRef50_A4JJP4 Cluster: Silent information regulator protein Si... 42 0.019 UniRef50_A3JEV2 Cluster: NAD-dependent deacetylase; n=2; Marinob... 42 0.019 UniRef50_Q4QB33 Cluster: Sir2-family protein-like protein; n=4; ... 42 0.019 UniRef50_Q2H5A0 Cluster: Putative uncharacterized protein; n=1; ... 42 0.019 UniRef50_O94640 Cluster: NAD-dependent histone deacetylase sir2;... 42 0.019 UniRef50_UPI0000E49AD8 Cluster: PREDICTED: similar to NAD-depend... 41 0.025 UniRef50_Q6C219 Cluster: Yarrowia lipolytica chromosome F of str... 41 0.025 UniRef50_A4QUX8 Cluster: Putative uncharacterized protein; n=1; ... 41 0.025 UniRef50_A1ZHW6 Cluster: NAD-dependent deacetylase; n=2; Microsc... 41 0.034 UniRef50_Q7QZ36 Cluster: GLP_464_21655_23334; n=1; Giardia lambl... 41 0.034 UniRef50_Q2HG51 Cluster: Putative uncharacterized protein; n=2; ... 41 0.034 UniRef50_Q899G3 Cluster: NAD-dependent deacetylase; n=19; cellul... 41 0.034 UniRef50_Q81NT6 Cluster: NAD-dependent deacetylase; n=11; Bacill... 41 0.034 UniRef50_UPI0000D578DC Cluster: PREDICTED: similar to sirtuin 5 ... 40 0.044 UniRef50_Q21KQ1 Cluster: Silent information regulator protein Si... 40 0.044 UniRef50_Q046W9 Cluster: NAD-dependent protein deacetylase, SIR2... 40 0.044 UniRef50_A6WG46 Cluster: Silent information regulator protein Si... 40 0.044 UniRef50_Q1EP52 Cluster: Transcriptional regulator Sir2 family p... 40 0.044 UniRef50_Q54QE6 Cluster: Zn finger-containing protein; n=5; Euka... 40 0.044 UniRef50_Q9USN7 Cluster: Sir2 family histone deacetylase Hst2; n... 40 0.044 UniRef50_Q5KG84 Cluster: Hst4 protein, putative; n=2; Filobasidi... 40 0.044 UniRef50_A3LRA1 Cluster: Transcriptional regulatory protein; n=2... 40 0.044 UniRef50_A1CD03 Cluster: SIR2 family histone deacetylase, putati... 40 0.044 UniRef50_Q67KQ0 Cluster: NAD-dependent deacetylase; n=1; Symbiob... 40 0.044 UniRef50_Q607X6 Cluster: NAD-dependent deacetylase; n=1; Methylo... 40 0.044 UniRef50_P53688 Cluster: NAD-dependent histone deacetylase HST4;... 40 0.044 UniRef50_Q3E2I1 Cluster: Silent information regulator protein Si... 40 0.059 UniRef50_Q22ZC3 Cluster: Transcriptional regulator, Sir2 family ... 40 0.059 UniRef50_A4VDQ9 Cluster: Chromatin regulatory protein sir2; n=1;... 40 0.059 UniRef50_A0DQW0 Cluster: Chromosome undetermined scaffold_6, who... 40 0.059 UniRef50_Q6BVM7 Cluster: Similar to CA4170|IPF7784 Candida albic... 40 0.059 UniRef50_Q4WFZ3 Cluster: SIR2 family histone deacetylase, putati... 40 0.059 UniRef50_Q7ZVK3 Cluster: NAD-dependent deacetylase sirtuin-2; n=... 40 0.059 UniRef50_P53687 Cluster: NAD-dependent histone deacetylase HST3;... 40 0.059 UniRef50_UPI00015B48CB Cluster: PREDICTED: similar to 85 kda cal... 40 0.078 UniRef50_UPI000023E2DA Cluster: hypothetical protein FG00460.1; ... 40 0.078 UniRef50_A6LP94 Cluster: Silent information regulator protein Si... 40 0.078 UniRef50_Q23YS7 Cluster: Transcriptional regulator, Sir2 family ... 40 0.078 UniRef50_Q4P3S4 Cluster: Putative uncharacterized protein; n=1; ... 40 0.078 UniRef50_A1CTI6 Cluster: SIR2 family histone deacetylase, putati... 40 0.078 UniRef50_O59923 Cluster: NAD-dependent histone deacetylase SIR2;... 40 0.078 UniRef50_Q8U1Q1 Cluster: NAD-dependent deacetylase; n=19; cellul... 40 0.078 UniRef50_UPI0000519F58 Cluster: PREDICTED: similar to Sirt4 CG31... 39 0.10 UniRef50_UPI00004997CB Cluster: Sir2 family transcriptional regu... 39 0.10 UniRef50_A4A980 Cluster: NAD-dependent deacetylase; n=5; Gammapr... 39 0.10 UniRef50_A1I9S7 Cluster: NAD-dependent deacetylase; n=1; Candida... 39 0.10 UniRef50_A1FG80 Cluster: Silent information regulator protein Si... 39 0.10 UniRef50_Q54P49 Cluster: Zn finger-containing protein; n=1; Dict... 39 0.10 UniRef50_Q298C7 Cluster: GA18650-PA; n=1; Drosophila pseudoobscu... 39 0.10 UniRef50_Q5KDE0 Cluster: NAD-dependent histone deacetylase, puta... 39 0.10 UniRef50_P06700 Cluster: NAD-dependent histone deacetylase SIR2;... 39 0.10 UniRef50_Q885X7 Cluster: NAD-dependent deacetylase 2; n=4; Pseud... 39 0.10 UniRef50_UPI000050FCF4 Cluster: COG0846: NAD-dependent protein d... 39 0.14 UniRef50_Q4S7H2 Cluster: Chromosome 13 SCAF14715, whole genome s... 39 0.14 UniRef50_Q03ZB1 Cluster: NAD-dependent protein deacetylase, SIR2... 39 0.14 UniRef50_Q8SSB6 Cluster: SIR2-LIKE PROTEIN INVOLVED IN TELOMERIC... 39 0.14 UniRef50_Q750H1 Cluster: AGL018Cp; n=1; Eremothecium gossypii|Re... 39 0.14 UniRef50_A5DJ74 Cluster: Putative uncharacterized protein; n=1; ... 39 0.14 UniRef50_A4RCT8 Cluster: Putative uncharacterized protein; n=3; ... 39 0.14 UniRef50_Q8R216 Cluster: NAD-dependent deacetylase sirtuin-4; n=... 39 0.14 UniRef50_Q9Y6E7 Cluster: NAD-dependent deacetylase sirtuin-4; n=... 39 0.14 UniRef50_A7HID4 Cluster: Silent information regulator protein Si... 38 0.18 UniRef50_A7H7B6 Cluster: Silent information regulator protein Si... 38 0.18 UniRef50_A0PU12 Cluster: Sir2-like regulatory protein; n=1; Myco... 38 0.18 UniRef50_Q8IRR5 Cluster: CG3187-PC, isoform C; n=4; Diptera|Rep:... 38 0.18 UniRef50_A2DKF0 Cluster: Transcriptional regulator, Sir2 family ... 38 0.18 UniRef50_Q6CAJ8 Cluster: Similar to sp|P53687 Saccharomyces cere... 38 0.18 UniRef50_A4QX96 Cluster: Putative uncharacterized protein; n=2; ... 38 0.18 UniRef50_A3LN35 Cluster: NAD-dependent histone deacetylase SIR2;... 38 0.18 UniRef50_A2QWZ2 Cluster: Function: human SIRT5 belongs to the Si... 38 0.18 UniRef50_Q7WLE5 Cluster: NAD-dependent deacetylase; n=47; Bacter... 38 0.18 UniRef50_UPI00015B4FA0 Cluster: PREDICTED: similar to chromatin ... 38 0.24 UniRef50_UPI00006CA40C Cluster: transcriptional regulator, Sir2 ... 38 0.24 UniRef50_Q4QKL5 Cluster: NAD-dependent deacetylase sirtuin 5; n=... 38 0.24 UniRef50_Q1D737 Cluster: NAD-dependent deacetylase; n=1; Myxococ... 38 0.24 UniRef50_A6XDL2 Cluster: Sirtuin 1; n=2; Schistosoma|Rep: Sirtui... 38 0.24 UniRef50_Q8IXJ6 Cluster: NAD-dependent deacetylase sirtuin-2; n=... 38 0.24 UniRef50_Q6C8C7 Cluster: Similar to DEHA0C01507g Debaryomyces ha... 38 0.31 UniRef50_A6SP88 Cluster: Putative uncharacterized protein; n=2; ... 38 0.31 UniRef50_Q9NTG7 Cluster: NAD-dependent deacetylase sirtuin-3, mi... 38 0.31 UniRef50_UPI0000499DEA Cluster: Sir2 family transcriptional regu... 37 0.41 UniRef50_A2ABY8 Cluster: Sirtuin 7 (Silent mating type informati... 37 0.41 UniRef50_Q1RL71 Cluster: Zinc finger protein; n=2; Ciona intesti... 37 0.41 UniRef50_Q882K4 Cluster: NAD-dependent deacetylase 3; n=5; Pseud... 37 0.41 UniRef50_Q7PS76 Cluster: ENSANGP00000025231; n=1; Anopheles gamb... 37 0.55 UniRef50_A2F9H1 Cluster: Transcriptional regulator, Sir2 family ... 37 0.55 UniRef50_Q89EA6 Cluster: NAD-dependent deacetylase 2; n=9; Prote... 37 0.55 UniRef50_Q07FY7 Cluster: Sirtuin (Silent mating type information... 36 0.72 UniRef50_Q62HT8 Cluster: Transcriptional regulator, Sir2 family;... 36 0.72 UniRef50_A4A8B4 Cluster: Silent information regulator protein Si... 36 0.72 UniRef50_A1ZZG3 Cluster: NAD-dependent deacetylase; n=35; Bacter... 36 0.72 UniRef50_A7SK95 Cluster: Predicted protein; n=1; Nematostella ve... 36 0.72 UniRef50_Q6FKU1 Cluster: Similar to sp|P53686 Saccharomyces cere... 36 0.72 UniRef50_Q88BY5 Cluster: NAD-dependent deacetylase; n=9; Bacteri... 36 0.72 UniRef50_Q9I4E1 Cluster: NAD-dependent deacetylase 2; n=6; Pseud... 36 0.72 UniRef50_Q1D9X2 Cluster: Sir2 family protein; n=1; Myxococcus xa... 36 0.96 UniRef50_Q6MJJ2 Cluster: NAD-dependent deacetylase; n=5; Proteob... 36 0.96 UniRef50_Q8FUC8 Cluster: NAD-dependent deacetylase 1; n=6; Coryn... 36 0.96 UniRef50_UPI00005A356B Cluster: PREDICTED: similar to NAD-depend... 36 1.3 UniRef50_Q1QTH0 Cluster: Silent information regulator protein Si... 36 1.3 UniRef50_A0JXS0 Cluster: Silent information regulator protein Si... 36 1.3 UniRef50_Q4DP02 Cluster: Silent information regulator 2, putativ... 36 1.3 UniRef50_A2F8N6 Cluster: Transcriptional regulator, Sir2 family ... 36 1.3 UniRef50_P48324 Cluster: Uncharacterized 24.3 kDa protein in psb... 36 1.3 UniRef50_Q9RL35 Cluster: NAD-dependent deacetylase 1; n=8; Actin... 36 1.3 UniRef50_Q9I4L0 Cluster: NAD-dependent deacetylase 1; n=10; Bact... 36 1.3 UniRef50_Q2U9Y7 Cluster: Sirtuin 4 and related class II sirtuins... 35 1.7 UniRef50_P53686 Cluster: NAD-dependent deacetylase HST2; n=4; Sa... 35 1.7 UniRef50_Q6AF12 Cluster: Regulatory protein, Sir2 family; n=2; A... 35 2.2 UniRef50_Q5P3W1 Cluster: NAD-dependent deacetylase 2; n=4; Prote... 35 2.2 UniRef50_Q4XD65 Cluster: Putative uncharacterized protein; n=1; ... 35 2.2 UniRef50_A2DKY5 Cluster: Transcriptional regulator, Sir2 family ... 35 2.2 UniRef50_A5DW75 Cluster: Putative uncharacterized protein; n=1; ... 35 2.2 UniRef50_A2QUR5 Cluster: Remark: the H. sapiens SIRT4 belongs to... 35 2.2 UniRef50_Q8F3Z6 Cluster: NAD-dependent deacetylase; n=4; Leptosp... 35 2.2 UniRef50_Q4APN6 Cluster: Silent information regulator protein Si... 34 2.9 UniRef50_A6Q946 Cluster: Transcriptional regulator, Sir2 family;... 34 2.9 UniRef50_A3WK56 Cluster: SIR2-like regulatory protein, NAD-depen... 34 2.9 UniRef50_Q54LF0 Cluster: Ankyrin repeat-containing protein; n=1;... 34 2.9 UniRef50_Q17JQ3 Cluster: Mitochondrial ribosomal protein, S34, p... 34 2.9 UniRef50_Q7S223 Cluster: Putative uncharacterized protein NCU059... 34 2.9 UniRef50_Q2KH01 Cluster: Putative uncharacterized protein; n=2; ... 34 2.9 UniRef50_Q25337 Cluster: NAD-dependent deacetylase SIR2 homolog;... 34 2.9 UniRef50_Q839C6 Cluster: NAD-dependent deacetylase; n=14; Bacill... 34 2.9 UniRef50_Q8A3H9 Cluster: NAD-dependent deacetylase; n=3; Bactero... 34 2.9 UniRef50_A6FYM4 Cluster: Sir2 family protein; n=1; Plesiocystis ... 34 3.9 UniRef50_A5K7T7 Cluster: NAD-dependent deacetylase, putative; n=... 34 3.9 UniRef50_Q8ZFR1 Cluster: NAD-dependent deacetylase; n=149; cellu... 34 3.9 UniRef50_O25849 Cluster: NAD-dependent deacetylase; n=11; Bacter... 34 3.9 UniRef50_A5WD15 Cluster: Silent information regulator protein Si... 33 5.1 UniRef50_Q1RPU9 Cluster: Zinc finger protein; n=1; Ciona intesti... 33 5.1 UniRef50_UPI0000E47C29 Cluster: PREDICTED: similar to dermatan/c... 33 6.7 UniRef50_UPI000023DCB3 Cluster: hypothetical protein FG05505.1; ... 33 6.7 UniRef50_A0Z2E4 Cluster: NAD-dependent deacetylase; n=1; marine ... 33 6.7 UniRef50_Q7QZ37 Cluster: GLP_464_19573_21615; n=1; Giardia lambl... 33 6.7 UniRef50_Q4RXH1 Cluster: Chromosome 11 SCAF14979, whole genome s... 33 8.9 UniRef50_Q7MVT1 Cluster: Ribonuclease BN, putative; n=1; Porphyr... 33 8.9 UniRef50_A0RQP1 Cluster: General glycosylation pathway protein; ... 33 8.9 UniRef50_A0C6J0 Cluster: Chromosome undetermined scaffold_152, w... 33 8.9 UniRef50_Q4WET3 Cluster: SIR2 family histone deacetylase, putati... 33 8.9 >UniRef50_Q9VH08 Cluster: CG6284-PA; n=9; Eumetazoa|Rep: CG6284-PA - Drosophila melanogaster (Fruit fly) Length = 317 Score = 132 bits (319), Expect = 8e-30 Identities = 58/86 (67%), Positives = 72/86 (83%) Frame = +2 Query: 257 GLSPYENKGILGVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGP 436 GLS Y+NKGILG PE FDS++ + +KC LA+L+K S H+V+HTGAGISTSAGIPDFRGP Sbjct: 8 GLSAYDNKGILGAPESFDSDEVVAEKCQELAELIKKSGHVVLHTGAGISTSAGIPDFRGP 67 Query: 437 NGVWTLEKEGKKPTINVSFADAQPQK 514 GVWTLE++G+KP NVSF +A+P K Sbjct: 68 KGVWTLEEKGEKPDFNVSFDEARPTK 93 >UniRef50_Q8N6T7-2 Cluster: Isoform 2 of Q8N6T7 ; n=5; Catarrhini|Rep: Isoform 2 of Q8N6T7 - Homo sapiens (Human) Length = 328 Score = 101 bits (243), Expect = 1e-20 Identities = 46/84 (54%), Positives = 61/84 (72%) Frame = +2 Query: 257 GLSPYENKGILGVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGP 436 GLSPY +KG G+PE FD ++L +K LA+LV S +V HTGAGIST++GIPDFRGP Sbjct: 8 GLSPYADKGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHTGAGISTASGIPDFRGP 67 Query: 437 NGVWTLEKEGKKPTINVSFADAQP 508 +GVWT+E+ G P + +F A+P Sbjct: 68 HGVWTMEERGLAPKFDTTFESARP 91 >UniRef50_Q8N6T7 Cluster: Mono-ADP-ribosyltransferase sirtuin-6; n=22; Euteleostomi|Rep: Mono-ADP-ribosyltransferase sirtuin-6 - Homo sapiens (Human) Length = 355 Score = 101 bits (243), Expect = 1e-20 Identities = 46/84 (54%), Positives = 61/84 (72%) Frame = +2 Query: 257 GLSPYENKGILGVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGP 436 GLSPY +KG G+PE FD ++L +K LA+LV S +V HTGAGIST++GIPDFRGP Sbjct: 8 GLSPYADKGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHTGAGISTASGIPDFRGP 67 Query: 437 NGVWTLEKEGKKPTINVSFADAQP 508 +GVWT+E+ G P + +F A+P Sbjct: 68 HGVWTMEERGLAPKFDTTFESARP 91 >UniRef50_Q9FE17 Cluster: Sir2-like protein; n=9; Magnoliophyta|Rep: Sir2-like protein - Arabidopsis thaliana (Mouse-ear cress) Length = 473 Score = 89.0 bits (211), Expect = 1e-16 Identities = 45/84 (53%), Positives = 58/84 (69%), Gaps = 1/84 (1%) Frame = +2 Query: 260 LSPYENKGILGVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPN 439 LS E+ G +G+ E FD + L K LA+L++ SKH+VV TGAGISTS GIPDFRGP Sbjct: 9 LSFIEDVGQVGMAEFFDPSHLLQCKIEELAKLIQKSKHLVVFTGAGISTSCGIPDFRGPK 68 Query: 440 GVWTLEKEGKK-PTINVSFADAQP 508 G+WTL++EGK P ++ F A P Sbjct: 69 GIWTLQREGKDLPKASLPFHRAMP 92 >UniRef50_Q7SB01 Cluster: Putative uncharacterized protein NCU07624.1; n=1; Neurospora crassa|Rep: Putative uncharacterized protein NCU07624.1 - Neurospora crassa Length = 437 Score = 80.6 bits (190), Expect = 3e-14 Identities = 38/73 (52%), Positives = 52/73 (71%), Gaps = 1/73 (1%) Frame = +2 Query: 299 EKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPT 478 E F++ + +++K +LA L++ SKH VV TGAG+STSAGIPDFRGP GVWTL +G++ T Sbjct: 12 EMFEAPEVIDRKAKVLADLIRKSKHFVVFTGAGVSTSAGIPDFRGPEGVWTLMAQGRQAT 71 Query: 479 -INVSFADAQPQK 514 +V A P K Sbjct: 72 KKSVDVLQAIPTK 84 >UniRef50_Q4UH74 Cluster: Sir2-like histone deacetylase, putative; n=2; Theileria|Rep: Sir2-like histone deacetylase, putative - Theileria annulata Length = 928 Score = 77.8 bits (183), Expect = 2e-13 Identities = 32/65 (49%), Positives = 47/65 (72%) Frame = +2 Query: 260 LSPYENKGILGVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPN 439 L NKG LG+ E FD+N ++ +K LL + + S + ++HTGAG+ST +GIPDFRGP+ Sbjct: 12 LKKNNNKGPLGLDELFDTNKQVTKKVNLLYEYLSKSNNTIIHTGAGVSTGSGIPDFRGPS 71 Query: 440 GVWTL 454 G+WT+ Sbjct: 72 GIWTV 76 >UniRef50_A5K3P4 Cluster: Putative uncharacterized protein; n=1; Plasmodium vivax|Rep: Putative uncharacterized protein - Plasmodium vivax Length = 1259 Score = 77.8 bits (183), Expect = 2e-13 Identities = 35/72 (48%), Positives = 49/72 (68%) Frame = +2 Query: 242 LQLCKGLSPYENKGILGVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIP 421 + + LS ENKG LG E F+ +++ +K L + ++ S+HIVVH GAGISTS+G+ Sbjct: 4 MNYARRLSKNENKGPLGEKEYFEDSEEEKRKIKKLIEKIRTSEHIVVHAGAGISTSSGLQ 63 Query: 422 DFRGPNGVWTLE 457 DFRGP G+WT E Sbjct: 64 DFRGPTGIWTNE 75 >UniRef50_A5AF92 Cluster: Putative uncharacterized protein; n=1; Vitis vinifera|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 343 Score = 77.0 bits (181), Expect = 4e-13 Identities = 35/63 (55%), Positives = 47/63 (74%), Gaps = 1/63 (1%) Frame = +2 Query: 323 LNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKK-PTINVSFAD 499 +++K LA +++ SKH+VV TGAGISTS GIPDFRGP G+WTL++EGK P ++ F Sbjct: 61 MHKKIERLAVMLRKSKHLVVFTGAGISTSCGIPDFRGPKGIWTLQREGKALPQASLPFHR 120 Query: 500 AQP 508 A P Sbjct: 121 AMP 123 >UniRef50_Q7RP35 Cluster: Sir2-like protein; n=5; Plasmodium (Vinckeia)|Rep: Sir2-like protein - Plasmodium yoelii yoelii Length = 1159 Score = 76.6 bits (180), Expect = 6e-13 Identities = 34/66 (51%), Positives = 48/66 (72%) Frame = +2 Query: 260 LSPYENKGILGVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPN 439 LS ENKG LG E F+ ++ +K +L + ++ S++IVVH+GAGISTS+G+ DFRGP Sbjct: 10 LSKNENKGPLGEKEYFEDEEEEKEKIKVLIEKIRTSEYIVVHSGAGISTSSGLQDFRGPT 69 Query: 440 GVWTLE 457 G+WT E Sbjct: 70 GIWTNE 75 >UniRef50_UPI0000D573CE Cluster: PREDICTED: similar to CG11305-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG11305-PA - Tribolium castaneum Length = 627 Score = 74.5 bits (175), Expect = 2e-12 Identities = 31/58 (53%), Positives = 47/58 (81%), Gaps = 1/58 (1%) Frame = +2 Query: 299 EKFDSNDK-LNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGK 469 E+F+ + L +KC++LAQ + ++H+VV+TGAGIST+A IPD+RGPNG+WT ++GK Sbjct: 96 EEFEEPPEVLKEKCLILAQAIAQAQHLVVYTGAGISTAAKIPDYRGPNGIWTRLQQGK 153 >UniRef50_Q1MT39 Cluster: Novel protein similar to vertebratesirtuin (Silent mating type information regulation 2 homolog) 7; n=2; Danio rerio|Rep: Novel protein similar to vertebratesirtuin (Silent mating type information regulation 2 homolog) 7 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 376 Score = 72.9 bits (171), Expect = 7e-12 Identities = 33/70 (47%), Positives = 49/70 (70%) Frame = +2 Query: 299 EKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPT 478 E FD + L K LA+ V+ +KH+V++TGAGIST+A IPD+RGPNGVWT ++G+ + Sbjct: 74 EVFDDAENLKTKVKQLAEAVQRAKHLVIYTGAGISTAASIPDYRGPNGVWTQLQKGRSVS 133 Query: 479 INVSFADAQP 508 + + A+P Sbjct: 134 TS-DLSQAEP 142 >UniRef50_A7AWG1 Cluster: Transcriptional regulator, Sir2 family domain containing protein; n=2; Babesia bovis|Rep: Transcriptional regulator, Sir2 family domain containing protein - Babesia bovis Length = 656 Score = 72.9 bits (171), Expect = 7e-12 Identities = 32/73 (43%), Positives = 51/73 (69%) Frame = +2 Query: 236 NVLQLCKGLSPYENKGILGVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAG 415 + L+ L P +NKG G + FD+ +++K +L+ +K++V+H+GAG+ST+AG Sbjct: 4 SALKYANQLRPNDNKGPCGGVQLFDNPADISKKFKQTVELLTRAKNVVLHSGAGMSTAAG 63 Query: 416 IPDFRGPNGVWTL 454 IPDFRGP+GVWT+ Sbjct: 64 IPDFRGPSGVWTV 76 >UniRef50_Q8N6T7-3 Cluster: Isoform 3 of Q8N6T7 ; n=2; Catarrhini|Rep: Isoform 3 of Q8N6T7 - Homo sapiens (Human) Length = 187 Score = 71.3 bits (167), Expect = 2e-11 Identities = 34/58 (58%), Positives = 43/58 (74%) Frame = +2 Query: 257 GLSPYENKGILGVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFR 430 GLSPY +KG G+PE FD ++L +K LA+LV S +V HTGAGIST++GIPDFR Sbjct: 8 GLSPYADKGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHTGAGISTASGIPDFR 65 >UniRef50_Q8IKW2 Cluster: Putative uncharacterized protein; n=1; Plasmodium falciparum 3D7|Rep: Putative uncharacterized protein - Plasmodium falciparum (isolate 3D7) Length = 1304 Score = 71.3 bits (167), Expect = 2e-11 Identities = 33/66 (50%), Positives = 46/66 (69%) Frame = +2 Query: 260 LSPYENKGILGVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPN 439 LS E KG LG E F+ ++ +K L + ++ S++IVVH+GAGISTS+G+ DFRGP Sbjct: 10 LSKNEYKGPLGEEEFFEDTEEEKKKVKELIEKIRSSEYIVVHSGAGISTSSGLQDFRGPT 69 Query: 440 GVWTLE 457 G+WT E Sbjct: 70 GIWTNE 75 >UniRef50_Q9NRC8 Cluster: NAD-dependent deacetylase sirtuin-7; n=24; Eumetazoa|Rep: NAD-dependent deacetylase sirtuin-7 - Homo sapiens (Human) Length = 400 Score = 71.3 bits (167), Expect = 2e-11 Identities = 36/73 (49%), Positives = 51/73 (69%) Frame = +2 Query: 299 EKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPT 478 E D ++L K LA V+++K++VV+TGAGIST+A IPD+RGPNGVWTL ++G+ Sbjct: 77 EVCDDPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYRGPNGVWTLLQKGR--- 133 Query: 479 INVSFADAQPQKP 517 +VS AD +P Sbjct: 134 -SVSAADLSEAEP 145 >UniRef50_Q175I4 Cluster: Chromatin regulatory protein sir2; n=3; Coelomata|Rep: Chromatin regulatory protein sir2 - Aedes aegypti (Yellowfever mosquito) Length = 720 Score = 68.5 bits (160), Expect = 1e-10 Identities = 30/57 (52%), Positives = 41/57 (71%) Frame = +2 Query: 299 EKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGK 469 EK D +++ K + LAQ + S H++V+TGAGISTSA IPD+RG G+WTL +GK Sbjct: 58 EKEDEPEEIETKALRLAQAIARSNHLMVYTGAGISTSAKIPDYRGSQGIWTLLAQGK 114 >UniRef50_UPI00015B56BB Cluster: PREDICTED: similar to ENSANGP00000025716; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to ENSANGP00000025716 - Nasonia vitripennis Length = 581 Score = 64.1 bits (149), Expect = 3e-09 Identities = 27/54 (50%), Positives = 39/54 (72%) Frame = +2 Query: 308 DSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGK 469 D+ + L +KC+ LA + + + V+TGAGIST+A IPD+RG NGVWT ++GK Sbjct: 91 DAPEILEEKCIRLAAAISRATSLAVYTGAGISTAASIPDYRGTNGVWTRLQQGK 144 >UniRef50_Q9VAQ1 Cluster: CG11305-PA; n=8; Coelomata|Rep: CG11305-PA - Drosophila melanogaster (Fruit fly) Length = 771 Score = 61.7 bits (143), Expect = 2e-08 Identities = 27/59 (45%), Positives = 41/59 (69%) Frame = +2 Query: 293 VPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGK 469 V E+ D+ + K LA ++ +KH+V +TGAGIST+A IPD+RG G+WTL ++G+ Sbjct: 99 VVEREDAPHVIEAKVEQLANIISQAKHLVCYTGAGISTAALIPDYRGSQGIWTLLQKGQ 157 >UniRef50_Q29QS4 Cluster: IP11347p; n=1; Drosophila melanogaster|Rep: IP11347p - Drosophila melanogaster (Fruit fly) Length = 98 Score = 61.3 bits (142), Expect = 2e-08 Identities = 27/42 (64%), Positives = 32/42 (76%) Frame = -2 Query: 507 GCASANDTLMVGFLPSFSKVHTPFGPLKSGIPAEVLMPAPVW 382 G AS+ +TL GF P S+V TP GP KSGIPA+VL+PAPVW Sbjct: 9 GLASSKETLKSGFSPFSSRVQTPLGPRKSGIPADVLIPAPVW 50 >UniRef50_UPI000049979A Cluster: Sir2 family transcriptional regulator; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Sir2 family transcriptional regulator - Entamoeba histolytica HM-1:IMSS Length = 319 Score = 57.2 bits (132), Expect = 4e-07 Identities = 25/46 (54%), Positives = 33/46 (71%) Frame = +2 Query: 311 SNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 S +++ C LA+++ SK +VV TGAGIS SAGIPDFR NG+W Sbjct: 9 SEEEIEFSCKSLARIISRSKRLVVLTGAGISVSAGIPDFRSRNGMW 54 >UniRef50_Q22KA8 Cluster: Transcriptional regulator, Sir2 family protein; n=3; Tetrahymena thermophila SB210|Rep: Transcriptional regulator, Sir2 family protein - Tetrahymena thermophila SB210 Length = 386 Score = 56.0 bits (129), Expect = 8e-07 Identities = 31/56 (55%), Positives = 36/56 (64%) Frame = +2 Query: 299 EKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEG 466 E FDS + L K LA ++K S H V TGAGISTSAGI DFR +GV T+ K G Sbjct: 13 EYFDSPELLEAKVTQLADMIKQSNHFVCFTGAGISTSAGIADFR--SGVNTVLKTG 66 >UniRef50_Q3F1F4 Cluster: SIR2 family protein; n=1; Bacillus thuringiensis serovar israelensis ATCC 35646|Rep: SIR2 family protein - Bacillus thuringiensis serovar israelensis ATCC 35646 Length = 241 Score = 54.8 bits (126), Expect = 2e-06 Identities = 25/43 (58%), Positives = 32/43 (74%) Frame = +2 Query: 347 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKP 475 A+L+K S HIVV TGAGIST +G+PD+R G+W +GKKP Sbjct: 6 AELIKKSNHIVVLTGAGISTDSGLPDYRSNGGLW----DGKKP 44 >UniRef50_A6DC77 Cluster: Silent information regulator protein Sir2; n=1; Caminibacter mediatlanticus TB-2|Rep: Silent information regulator protein Sir2 - Caminibacter mediatlanticus TB-2 Length = 243 Score = 54.8 bits (126), Expect = 2e-06 Identities = 21/35 (60%), Positives = 29/35 (82%) Frame = +2 Query: 347 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 451 A+++KDSK++V TGAGIS +GIP FRGP G+W+ Sbjct: 8 AEIIKDSKNLVAFTGAGISVESGIPTFRGPTGLWS 42 >UniRef50_A4M603 Cluster: Silent information regulator protein Sir2; n=1; Petrotoga mobilis SJ95|Rep: Silent information regulator protein Sir2 - Petrotoga mobilis SJ95 Length = 256 Score = 52.8 bits (121), Expect = 8e-06 Identities = 22/35 (62%), Positives = 30/35 (85%) Frame = +2 Query: 347 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 451 A+L+ +S I V +GAG+ST+AGIPDFRGPNG++T Sbjct: 9 AELIYNSNSIAVLSGAGMSTNAGIPDFRGPNGIYT 43 >UniRef50_Q974M6 Cluster: NAD-dependent deacetylase; n=8; Thermoprotei|Rep: NAD-dependent deacetylase - Sulfolobus tokodaii Length = 250 Score = 52.8 bits (121), Expect = 8e-06 Identities = 21/39 (53%), Positives = 29/39 (74%) Frame = +2 Query: 332 KCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 +C + L+ S + + TGAGIST++GIPDFRGPNG+W Sbjct: 2 ECDKVGDLLLTSTYAIAFTGAGISTASGIPDFRGPNGLW 40 >UniRef50_A3ZMQ7 Cluster: Sir2 family, possible ADP ribosyltransferase; n=1; Blastopirellula marina DSM 3645|Rep: Sir2 family, possible ADP ribosyltransferase - Blastopirellula marina DSM 3645 Length = 252 Score = 52.0 bits (119), Expect = 1e-05 Identities = 22/37 (59%), Positives = 29/37 (78%) Frame = +2 Query: 341 LLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 451 L+A+ + +S+ V+ TGAGIST +GIPDFR P GVWT Sbjct: 9 LVARWLAESESTVLFTGAGISTESGIPDFRSPGGVWT 45 >UniRef50_Q89LY4 Cluster: NAD-dependent deacetylase 1; n=12; Proteobacteria|Rep: NAD-dependent deacetylase 1 - Bradyrhizobium japonicum Length = 254 Score = 52.0 bits (119), Expect = 1e-05 Identities = 21/36 (58%), Positives = 26/36 (72%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 451 L ++ ++K IV TGAGIST GIPDFR P G+WT Sbjct: 15 LGDMIAEAKTIVPFTGAGISTECGIPDFRSPGGIWT 50 >UniRef50_Q95Q89 Cluster: Yeast sir related protein 2.4; n=2; Caenorhabditis|Rep: Yeast sir related protein 2.4 - Caenorhabditis elegans Length = 299 Score = 51.2 bits (117), Expect = 2e-05 Identities = 26/53 (49%), Positives = 32/53 (60%) Frame = +2 Query: 350 QLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFADAQP 508 Q + K I V GAG+ST + +PDFRG GVWTL+ EGK V F A+P Sbjct: 50 QAKQTGKPIFVLIGAGVSTGSKLPDFRGKQGVWTLQAEGKHAE-GVDFQVARP 101 >UniRef50_Q8ZT00 Cluster: NAD-dependent deacetylase 2; n=2; cellular organisms|Rep: NAD-dependent deacetylase 2 - Pyrobaculum aerophilum Length = 249 Score = 50.8 bits (116), Expect = 3e-05 Identities = 20/35 (57%), Positives = 26/35 (74%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 +A L+ S+H VV TGAGIS +G+P FRGP G+W Sbjct: 3 VADLLASSRHCVVFTGAGISAESGVPTFRGPGGLW 37 >UniRef50_Q3A6W7 Cluster: NAD-dependent protein deacetylases, SIR2 family; n=2; Pelobacter|Rep: NAD-dependent protein deacetylases, SIR2 family - Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1) Length = 278 Score = 50.4 bits (115), Expect = 4e-05 Identities = 20/55 (36%), Positives = 36/55 (65%) Frame = +2 Query: 347 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFADAQPQ 511 A +++ S+ +V +GAGIST+AGIPDFRGP G++ + + ++ + +P+ Sbjct: 26 ADMIRRSRCVVTLSGAGISTAAGIPDFRGPQGLYVTRRYDPEKVFDIDWFHREPR 80 >UniRef50_Q54GV7 Cluster: NAD(+)-dependent deacetylase, silent information regulator protein (Sir2) family protein; n=1; Dictyostelium discoideum AX4|Rep: NAD(+)-dependent deacetylase, silent information regulator protein (Sir2) family protein - Dictyostelium discoideum AX4 Length = 542 Score = 50.0 bits (114), Expect = 5e-05 Identities = 24/45 (53%), Positives = 32/45 (71%), Gaps = 1/45 (2%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW-TLEKEGKKP 475 + QL + SK+IV+ TGAG+S S GIPDFR GV+ T+EK+ P Sbjct: 293 VCQLFESSKNIVIITGAGVSVSCGIPDFRSKGGVYETIEKKYNLP 337 >UniRef50_A7EMW8 Cluster: Putative uncharacterized protein; n=1; Sclerotinia sclerotiorum 1980|Rep: Putative uncharacterized protein - Sclerotinia sclerotiorum 1980 Length = 533 Score = 49.6 bits (113), Expect = 7e-05 Identities = 24/39 (61%), Positives = 30/39 (76%), Gaps = 1/39 (2%) Frame = +2 Query: 353 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT-LEKEG 466 L+K++K I+V TGAGISTS GIPDFR NG++ LE G Sbjct: 203 LIKNAKKIIVITGAGISTSLGIPDFRSANGLYAQLEDTG 241 >UniRef50_UPI00006CB0CC Cluster: transcriptional regulator, Sir2 family protein; n=1; Tetrahymena thermophila SB210|Rep: transcriptional regulator, Sir2 family protein - Tetrahymena thermophila SB210 Length = 442 Score = 49.2 bits (112), Expect = 1e-04 Identities = 29/74 (39%), Positives = 44/74 (59%), Gaps = 8/74 (10%) Frame = +2 Query: 275 NKGILGVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFR-GPN---- 439 N + E DS ++++ K L +L++ SK+ V+ TGAG+ST++GIPD+R G N Sbjct: 38 NPRLKDTQEHQDSPEQIDTKVNQLIELLQKSKNAVILTGAGVSTASGIPDYRSGANTILK 97 Query: 440 ---GVWTLEKEGKK 472 G W LE+ KK Sbjct: 98 TGPGKWELEENKKK 111 >UniRef50_UPI000049971A Cluster: Sir2 family transcriptional regulator; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Sir2 family transcriptional regulator - Entamoeba histolytica HM-1:IMSS Length = 285 Score = 49.2 bits (112), Expect = 1e-04 Identities = 20/45 (44%), Positives = 32/45 (71%) Frame = +2 Query: 314 NDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 +D ++ ++A+ ++ SK++ V TGAGIS +GIPDFR NG+W Sbjct: 18 DDSIDIDIEMIARSMEKSKNVTVLTGAGISVESGIPDFRSSNGLW 62 >UniRef50_Q5YR82 Cluster: Putative Sir2 family regulator; n=1; Nocardia farcinica|Rep: Putative Sir2 family regulator - Nocardia farcinica Length = 248 Score = 49.2 bits (112), Expect = 1e-04 Identities = 22/29 (75%), Positives = 23/29 (79%) Frame = +2 Query: 365 SKHIVVHTGAGISTSAGIPDFRGPNGVWT 451 S I V TGAGIST +GIPDFRGP GVWT Sbjct: 9 SGRIGVLTGAGISTDSGIPDFRGPRGVWT 37 >UniRef50_Q0AY57 Cluster: Regulatory protein, sir2 family; n=1; Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep: Regulatory protein, sir2 family - Syntrophomonas wolfei subsp. wolfei (strain Goettingen) Length = 253 Score = 49.2 bits (112), Expect = 1e-04 Identities = 25/56 (44%), Positives = 34/56 (60%), Gaps = 1/56 (1%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGK-KPTINVSFADAQP 508 + +++ S + VV TGAGIST AGIPDFRGP G++ E + IN+ F P Sbjct: 8 VVEILDRSHNTVVVTGAGISTEAGIPDFRGPEGIYRKLGENRVMKIINIDFFRNNP 63 >UniRef50_UPI00015B57C0 Cluster: PREDICTED: similar to GA18743-PA; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to GA18743-PA - Nasonia vitripennis Length = 871 Score = 48.8 bits (111), Expect = 1e-04 Identities = 19/36 (52%), Positives = 30/36 (83%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 451 + +L+K+SK+I+V TGAG+S S GIPDFR +G+++ Sbjct: 197 VVELIKNSKNIIVLTGAGVSVSCGIPDFRSRDGIYS 232 >UniRef50_Q9WYW0 Cluster: NAD-dependent deacetylase; n=4; Thermotoga|Rep: NAD-dependent deacetylase - Thermotoga maritima Length = 246 Score = 48.8 bits (111), Expect = 1e-04 Identities = 23/54 (42%), Positives = 36/54 (66%) Frame = +2 Query: 353 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFADAQPQK 514 L+ +S+ V TGAGIST +GIPDFRGPNG++ K+ + ++ F + P++ Sbjct: 9 LLNESRLTVTLTGAGISTPSGIPDFRGPNGIY---KKYSQNVFDIDFFYSHPEE 59 >UniRef50_Q8ZU41 Cluster: NAD-dependent deacetylase 1; n=3; Pyrobaculum|Rep: NAD-dependent deacetylase 1 - Pyrobaculum aerophilum Length = 254 Score = 48.8 bits (111), Expect = 1e-04 Identities = 21/35 (60%), Positives = 26/35 (74%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 +A L+ S V TGAG+ST++GIPDFRGP GVW Sbjct: 13 VASLIARSSCNVALTGAGVSTASGIPDFRGPQGVW 47 >UniRef50_Q2LSF2 Cluster: Sir2 family of NAD+-dependent deacetylase; n=2; Syntrophus aciditrophicus SB|Rep: Sir2 family of NAD+-dependent deacetylase - Syntrophus aciditrophicus (strain SB) Length = 271 Score = 48.4 bits (110), Expect = 2e-04 Identities = 20/46 (43%), Positives = 31/46 (67%) Frame = +2 Query: 311 SNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 S+ + +K +A ++ + +VV TGAG+ST +GIPDFR P G+W Sbjct: 7 SDREFMEKIDAVADMIWMAGRVVVFTGAGVSTESGIPDFRSPGGLW 52 >UniRef50_Q8CJM9 Cluster: NAD-dependent deacetylase 2; n=3; Actinomycetales|Rep: NAD-dependent deacetylase 2 - Streptomyces coelicolor Length = 241 Score = 48.4 bits (110), Expect = 2e-04 Identities = 17/33 (51%), Positives = 26/33 (78%) Frame = +2 Query: 374 IVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKK 472 + + +GAG+ST +GIPD+RGPNG+W + E +K Sbjct: 7 VAILSGAGVSTDSGIPDYRGPNGLWRRDPEAEK 39 >UniRef50_Q2YZT2 Cluster: Putative uncharacterized protein; n=1; uncultured delta proteobacterium|Rep: Putative uncharacterized protein - uncultured delta proteobacterium Length = 254 Score = 48.0 bits (109), Expect = 2e-04 Identities = 19/34 (55%), Positives = 27/34 (79%) Frame = +2 Query: 350 QLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 451 Q++K SK+++ TGAGIS +GIPDFR P G+W+ Sbjct: 11 QMIK-SKYVIAMTGAGISVESGIPDFRSPGGLWS 43 >UniRef50_A7B9E8 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 251 Score = 47.6 bits (108), Expect = 3e-04 Identities = 25/64 (39%), Positives = 35/64 (54%), Gaps = 1/64 (1%) Frame = +2 Query: 323 LNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTI-NVSFAD 499 +N LA + S V GAG+ST +GIPDFRG NG + E+E T+ ++ F + Sbjct: 1 MNSDVSTLAAWIAASPSTVFFGGAGVSTESGIPDFRGANGFYFQEREIPLETVLSIDFFE 60 Query: 500 AQPQ 511 PQ Sbjct: 61 RHPQ 64 >UniRef50_A6RRE3 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 526 Score = 47.6 bits (108), Expect = 3e-04 Identities = 20/33 (60%), Positives = 27/33 (81%) Frame = +2 Query: 350 QLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 +L++ +K I+V TGAGISTS GIPDFR NG++ Sbjct: 198 ELIRGAKKIIVITGAGISTSLGIPDFRSANGLY 230 >UniRef50_Q5KZE8 Cluster: NAD-dependent deacetylase 2; n=3; Bacteria|Rep: NAD-dependent deacetylase 2 - Geobacillus kaustophilus Length = 247 Score = 47.6 bits (108), Expect = 3e-04 Identities = 21/38 (55%), Positives = 28/38 (73%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLE 457 LAQ +K++ I V TGAG+ST +GIPDFR NG++ E Sbjct: 7 LAQWIKEANTIAVLTGAGMSTESGIPDFRSENGLYAQE 44 >UniRef50_UPI0000E49846 Cluster: PREDICTED: similar to Sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae); n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae) - Strongylocentrotus purpuratus Length = 521 Score = 47.2 bits (107), Expect = 4e-04 Identities = 19/27 (70%), Positives = 22/27 (81%) Frame = +2 Query: 428 RGPNGVWTLEKEGKKPTINVSFADAQP 508 RGP GVWTLEK+GKKP NV+F A+P Sbjct: 11 RGPKGVWTLEKQGKKPEANVTFDTAKP 37 >UniRef50_Q5KA61 Cluster: Histone deacetylase, putative; n=1; Filobasidiella neoformans|Rep: Histone deacetylase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 596 Score = 47.2 bits (107), Expect = 4e-04 Identities = 23/40 (57%), Positives = 30/40 (75%), Gaps = 1/40 (2%) Frame = +2 Query: 353 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT-LEKEGK 469 L+ SK I+V +GAGISTS GIPDFR G++ L++EGK Sbjct: 152 LLAKSKKIIVLSGAGISTSCGIPDFRSSTGLYAQLQEEGK 191 >UniRef50_A6R1B0 Cluster: Predicted protein; n=2; Onygenales|Rep: Predicted protein - Ajellomyces capsulatus NAm1 Length = 547 Score = 47.2 bits (107), Expect = 4e-04 Identities = 26/55 (47%), Positives = 35/55 (63%), Gaps = 1/55 (1%) Frame = +2 Query: 341 LLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW-TLEKEGKKPTINVSFADA 502 LL + ++ + IVV GAGIS SAGIPDFR +G++ TL+K+ K T DA Sbjct: 94 LLLKALQKKRKIVVIAGAGISVSAGIPDFRSAHGLFKTLKKDHKLKTSGKQLFDA 148 >UniRef50_A2Q9C4 Cluster: Contig An01c0250, complete genome; n=18; Pezizomycotina|Rep: Contig An01c0250, complete genome - Aspergillus niger Length = 495 Score = 47.2 bits (107), Expect = 4e-04 Identities = 25/50 (50%), Positives = 33/50 (66%), Gaps = 2/50 (4%) Frame = +2 Query: 287 LGVPEKFDSNDKLNQKCVL--LAQLVKDSKHIVVHTGAGISTSAGIPDFR 430 + + +F KL Q + +L+K+SK+IVV TGAGISTS GIPDFR Sbjct: 150 IAISREFSRRPKLPQYNTIDDAVKLLKESKNIVVLTGAGISTSLGIPDFR 199 >UniRef50_O96505 Cluster: SIR2; n=4; Sophophora|Rep: SIR2 - Drosophila melanogaster (Fruit fly) Length = 823 Score = 46.8 bits (106), Expect = 5e-04 Identities = 20/32 (62%), Positives = 25/32 (78%) Frame = +2 Query: 353 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 LVK S+ I+V TGAG+S S GIPDFR NG++ Sbjct: 215 LVKKSQKIIVLTGAGVSVSCGIPDFRSTNGIY 246 >UniRef50_Q5AQ47 Cluster: Potential Sir2 family histone deacetylase; n=2; Candida albicans|Rep: Potential Sir2 family histone deacetylase - Candida albicans (Yeast) Length = 657 Score = 46.8 bits (106), Expect = 5e-04 Identities = 20/35 (57%), Positives = 29/35 (82%) Frame = +2 Query: 350 QLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTL 454 +L+++SK+I+V TGAGISTS GIPDFR G +++ Sbjct: 296 KLIENSKNIMVITGAGISTSLGIPDFRSSQGFYSM 330 >UniRef50_Q8REC3 Cluster: NAD-dependent deacetylase; n=3; Fusobacterium nucleatum|Rep: NAD-dependent deacetylase - Fusobacterium nucleatum subsp. nucleatum Length = 252 Score = 46.8 bits (106), Expect = 5e-04 Identities = 21/55 (38%), Positives = 39/55 (70%), Gaps = 1/55 (1%) Frame = +2 Query: 314 NDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW-TLEKEGKKP 475 + K ++K + L +++K++K++V GAG ST +G+ DFRG +G++ TL K+ +P Sbjct: 2 DSKRDEKILELVKILKNTKYLVFFGGAGTSTDSGVKDFRGKDGLYKTLYKDKYRP 56 >UniRef50_Q8R984 Cluster: NAD-dependent deacetylase 2; n=1; Thermoanaerobacter tengcongensis|Rep: NAD-dependent deacetylase 2 - Thermoanaerobacter tengcongensis Length = 250 Score = 46.8 bits (106), Expect = 5e-04 Identities = 21/35 (60%), Positives = 27/35 (77%), Gaps = 1/35 (2%) Frame = +2 Query: 347 AQLVKDSKHIVVHTGAGISTSAGIPDFRGP-NGVW 448 A+L+K S+ +V TGAGIST +GIPDFR P G+W Sbjct: 14 AELIKSSQKTMVLTGAGISTESGIPDFRSPGTGLW 48 >UniRef50_Q23A43 Cluster: Transcriptional regulator, Sir2 family protein; n=2; Tetrahymena thermophila SB210|Rep: Transcriptional regulator, Sir2 family protein - Tetrahymena thermophila SB210 Length = 503 Score = 46.4 bits (105), Expect = 7e-04 Identities = 22/40 (55%), Positives = 26/40 (65%) Frame = +2 Query: 347 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEG 466 AQL KD K +V TGAGIS ++GIP FRG EK+G Sbjct: 118 AQLFKDKKKVVFLTGAGISVASGIPTFRGVGAAPLFEKDG 157 >UniRef50_Q1RPU3 Cluster: Zinc finger protein; n=1; Ciona intestinalis|Rep: Zinc finger protein - Ciona intestinalis (Transparent sea squirt) Length = 737 Score = 46.4 bits (105), Expect = 7e-04 Identities = 23/56 (41%), Positives = 36/56 (64%) Frame = +2 Query: 284 ILGVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 451 I+ P++ D +N + +L+K SK I+V TGAG+S S GIPDFR +G+++ Sbjct: 162 IISEPKRRKKLDTVNTLSDAI-RLIKTSKKILVLTGAGVSVSCGIPDFRSRDGIYS 216 >UniRef50_A7DQD6 Cluster: Silent information regulator protein Sir2; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Silent information regulator protein Sir2 - Candidatus Nitrosopumilus maritimus SCM1 Length = 242 Score = 46.4 bits (105), Expect = 7e-04 Identities = 23/48 (47%), Positives = 30/48 (62%) Frame = +2 Query: 356 VKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFAD 499 VK++K IV TGAGIS +GIP FRG +G+W K TI+ + D Sbjct: 11 VKNAKKIVFVTGAGISQESGIPTFRGKDGLWRNYDAMKLATIDAFYDD 58 >UniRef50_Q21921 Cluster: NAD-dependent deacetylase SIR2 homolog; n=2; Caenorhabditis|Rep: NAD-dependent deacetylase SIR2 homolog - Caenorhabditis elegans Length = 607 Score = 46.4 bits (105), Expect = 7e-04 Identities = 19/33 (57%), Positives = 25/33 (75%) Frame = +2 Query: 350 QLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 +L K KHI+V TGAG+S S GIPDFR +G++ Sbjct: 140 ELFKTKKHILVLTGAGVSVSCGIPDFRSKDGIY 172 >UniRef50_O07595 Cluster: NAD-dependent deacetylase; n=3; Bacillus|Rep: NAD-dependent deacetylase - Bacillus subtilis Length = 247 Score = 46.4 bits (105), Expect = 7e-04 Identities = 18/33 (54%), Positives = 26/33 (78%) Frame = +2 Query: 353 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 451 ++ +++ IVV TGAG+ST +GIPDFR G+WT Sbjct: 7 ILHEAQRIVVLTGAGMSTESGIPDFRSAGGIWT 39 >UniRef50_A6TNA0 Cluster: Silent information regulator protein Sir2; n=1; Alkaliphilus metalliredigens QYMF|Rep: Silent information regulator protein Sir2 - Alkaliphilus metalliredigens QYMF Length = 249 Score = 46.0 bits (104), Expect = 9e-04 Identities = 19/46 (41%), Positives = 28/46 (60%) Frame = +2 Query: 311 SNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 + +++ + LA L+K SK V+ TGAG+ T + IPDFR G W Sbjct: 6 NGERMKDGVIKLASLIKKSKDTVILTGAGMDTESNIPDFRSEKGWW 51 >UniRef50_A6G0H3 Cluster: Silent information regulator protein Sir2; n=1; Plesiocystis pacifica SIR-1|Rep: Silent information regulator protein Sir2 - Plesiocystis pacifica SIR-1 Length = 288 Score = 46.0 bits (104), Expect = 9e-04 Identities = 19/34 (55%), Positives = 24/34 (70%) Frame = +2 Query: 374 IVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKP 475 +VV TGAGIS +GIP FRGP G WT+ + +P Sbjct: 31 VVVTTGAGISAESGIPTFRGPEGYWTVGAKEYRP 64 >UniRef50_A0NQ49 Cluster: Silent information regulator protein Sir2; n=1; Stappia aggregata IAM 12614|Rep: Silent information regulator protein Sir2 - Stappia aggregata IAM 12614 Length = 260 Score = 46.0 bits (104), Expect = 9e-04 Identities = 18/28 (64%), Positives = 22/28 (78%) Frame = +2 Query: 368 KHIVVHTGAGISTSAGIPDFRGPNGVWT 451 + IV TGAGIST +GIPDFR P G+W+ Sbjct: 23 RQIVALTGAGISTESGIPDFRSPGGIWS 50 >UniRef50_Q2GZ88 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 895 Score = 46.0 bits (104), Expect = 9e-04 Identities = 20/37 (54%), Positives = 29/37 (78%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTL 454 +A + S+ +VV TGAGIST++GIPDFR NG+++L Sbjct: 17 IANTLWKSRKVVVITGAGISTNSGIPDFRSENGLYSL 53 >UniRef50_A6PTK3 Cluster: Silent information regulator protein Sir2; n=1; Victivallis vadensis ATCC BAA-548|Rep: Silent information regulator protein Sir2 - Victivallis vadensis ATCC BAA-548 Length = 248 Score = 45.6 bits (103), Expect = 0.001 Identities = 21/42 (50%), Positives = 29/42 (69%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGK 469 L Q++++S+ + TGAGIST +GI DFRG NGV+ GK Sbjct: 5 LKQMLQESRRTLAFTGAGISTLSGIRDFRGKNGVYLEPWHGK 46 >UniRef50_A5UYK2 Cluster: Silent information regulator protein Sir2; n=2; Roseiflexus|Rep: Silent information regulator protein Sir2 - Roseiflexus sp. RS-1 Length = 261 Score = 45.6 bits (103), Expect = 0.001 Identities = 20/34 (58%), Positives = 24/34 (70%) Frame = +2 Query: 347 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 A L+ + V TGAGIST +GIPDFRGP+G W Sbjct: 15 ADLLGRAHSAVAITGAGISTPSGIPDFRGPDGAW 48 >UniRef50_Q5BVF7 Cluster: SJCHGC03105 protein; n=2; Schistosoma japonicum|Rep: SJCHGC03105 protein - Schistosoma japonicum (Blood fluke) Length = 181 Score = 45.6 bits (103), Expect = 0.001 Identities = 26/54 (48%), Positives = 35/54 (64%), Gaps = 3/54 (5%) Frame = +2 Query: 344 LAQLVKDSK--HIVVHTGAGISTSAGIPDFRGP-NGVWTLEKEGKKPTINVSFA 496 ++QL++D K IV GAGIST+AGIPDFR P +GV+ +E PT F+ Sbjct: 52 VSQLIQDGKINKIVTMVGAGISTAAGIPDFRSPSSGVYDNLEEFNLPTPTTIFS 105 >UniRef50_Q12Y78 Cluster: Silent information regulator protein Sir2; n=1; Methanococcoides burtonii DSM 6242|Rep: Silent information regulator protein Sir2 - Methanococcoides burtonii (strain DSM 6242) Length = 245 Score = 45.6 bits (103), Expect = 0.001 Identities = 20/35 (57%), Positives = 29/35 (82%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 L L+++S++ VV TGAG+ST +GIPDFRG +GV+ Sbjct: 4 LFSLLENSEYCVVLTGAGVSTFSGIPDFRGRSGVY 38 >UniRef50_Q73KE1 Cluster: NAD-dependent deacetylase; n=1; Treponema denticola|Rep: NAD-dependent deacetylase - Treponema denticola Length = 251 Score = 45.6 bits (103), Expect = 0.001 Identities = 23/53 (43%), Positives = 34/53 (64%) Frame = +2 Query: 341 LLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFAD 499 L +++ K ++H+V TGAGIST AGI DFRG +G++ K I+V + D Sbjct: 11 LFSEITK-ARHLVAFTGAGISTLAGIKDFRGKDGLYKQPNTEKMFDIDVFYRD 62 >UniRef50_A6P1S7 Cluster: Putative uncharacterized protein; n=2; Bacteria|Rep: Putative uncharacterized protein - Bacteroides capillosus ATCC 29799 Length = 262 Score = 45.2 bits (102), Expect = 0.002 Identities = 22/65 (33%), Positives = 40/65 (61%), Gaps = 1/65 (1%) Frame = +2 Query: 323 LNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTI-NVSFAD 499 + + LL + + +S IV GAG+ST +GIPDFR +G++ + + TI + +F + Sbjct: 21 MEENRALLQRWIDESSRIVFFGGAGVSTESGIPDFRSVDGLYNQQYDYPPETILSHTFYE 80 Query: 500 AQPQK 514 A+P++ Sbjct: 81 ARPEE 85 >UniRef50_A0LG97 Cluster: Silent information regulator protein Sir2; n=1; Syntrophobacter fumaroxidans MPOB|Rep: Silent information regulator protein Sir2 - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 248 Score = 45.2 bits (102), Expect = 0.002 Identities = 19/35 (54%), Positives = 27/35 (77%) Frame = +2 Query: 347 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 451 A+L+ S++ VV TGAGIS +GIPDFR +G+W+ Sbjct: 8 AELLLRSRYTVVLTGAGISVESGIPDFRSKDGLWS 42 >UniRef50_Q9FY91 Cluster: SIR2-family protein; n=12; Magnoliophyta|Rep: SIR2-family protein - Arabidopsis thaliana (Mouse-ear cress) Length = 451 Score = 45.2 bits (102), Expect = 0.002 Identities = 21/50 (42%), Positives = 30/50 (60%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSF 493 L +L + S + + TGAG+ST GIPD+R PNG ++ G KP + F Sbjct: 161 LYRLFEQSSRLTILTGAGVSTECGIPDYRSPNGAYS---SGFKPITHQEF 207 >UniRef50_A7SX90 Cluster: Predicted protein; n=3; Eumetazoa|Rep: Predicted protein - Nematostella vectensis Length = 306 Score = 45.2 bits (102), Expect = 0.002 Identities = 18/35 (51%), Positives = 27/35 (77%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 + +L+K K+I+V TGAG+S S GIPDFR +G++ Sbjct: 62 VVRLIKKCKNIIVLTGAGVSVSCGIPDFRSRDGIY 96 >UniRef50_A7EC18 Cluster: Putative uncharacterized protein; n=1; Sclerotinia sclerotiorum 1980|Rep: Putative uncharacterized protein - Sclerotinia sclerotiorum 1980 Length = 446 Score = 45.2 bits (102), Expect = 0.002 Identities = 22/33 (66%), Positives = 28/33 (84%), Gaps = 2/33 (6%) Frame = +2 Query: 344 LAQLVKD--SKHIVVHTGAGISTSAGIPDFRGP 436 +A+ +K+ +K+IVV TGAGISTSAGIPDFR P Sbjct: 27 VAEFIKNGQAKNIVVLTGAGISTSAGIPDFRSP 59 >UniRef50_Q8CNF4 Cluster: NAD-dependent deacetylase; n=17; Staphylococcus|Rep: NAD-dependent deacetylase - Staphylococcus epidermidis (strain ATCC 12228) Length = 246 Score = 45.2 bits (102), Expect = 0.002 Identities = 20/45 (44%), Positives = 30/45 (66%), Gaps = 1/45 (2%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW-TLEKEGKKP 475 L +V +S IV TGAG+S ++GIPDFR G++ + K+G+ P Sbjct: 9 LKDIVNNSNQIVFFTGAGVSVASGIPDFRSMGGLYDEISKDGQSP 53 >UniRef50_UPI0000D55B5A Cluster: PREDICTED: similar to CG5216-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG5216-PA - Tribolium castaneum Length = 722 Score = 44.8 bits (101), Expect = 0.002 Identities = 18/35 (51%), Positives = 28/35 (80%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 + +LVK +++I+V TGAG+S S GIPDFR +G++ Sbjct: 204 VVRLVKGAQNIIVLTGAGVSVSCGIPDFRSRDGIY 238 >UniRef50_UPI000051AA14 Cluster: PREDICTED: similar to NAD-dependent deacetylase sirtuin-1 (hSIRT1) (hSIR2) (SIR2-like protein 1); n=1; Apis mellifera|Rep: PREDICTED: similar to NAD-dependent deacetylase sirtuin-1 (hSIRT1) (hSIR2) (SIR2-like protein 1) - Apis mellifera Length = 868 Score = 44.8 bits (101), Expect = 0.002 Identities = 17/36 (47%), Positives = 28/36 (77%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 451 + +L+++S I+V TGAG+S S GIPDFR +G+++ Sbjct: 196 VVRLIRNSNRIIVLTGAGVSVSCGIPDFRSRDGIYS 231 >UniRef50_Q23E36 Cluster: Transcriptional regulator, Sir2 family protein; n=1; Tetrahymena thermophila SB210|Rep: Transcriptional regulator, Sir2 family protein - Tetrahymena thermophila SB210 Length = 1348 Score = 44.8 bits (101), Expect = 0.002 Identities = 19/31 (61%), Positives = 25/31 (80%) Frame = +2 Query: 359 KDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 451 K +I+ TGAGISTS+GIPDFR PNG+++ Sbjct: 18 KQINNILFLTGAGISTSSGIPDFRSPNGLYS 48 >UniRef50_A2F8E1 Cluster: Transcriptional regulator, Sir2 family protein; n=1; Trichomonas vaginalis G3|Rep: Transcriptional regulator, Sir2 family protein - Trichomonas vaginalis G3 Length = 331 Score = 44.8 bits (101), Expect = 0.002 Identities = 23/49 (46%), Positives = 32/49 (65%), Gaps = 3/49 (6%) Frame = +2 Query: 335 CVLLAQLVKDS--KHIVVHTGAGISTSAGIPDFRGPN-GVWTLEKEGKK 472 C +LAQ + K+++V TGAGIST+AGIPDFR P G++ K + Sbjct: 7 CEILAQKIISGNYKNVIVLTGAGISTAAGIPDFRSPAIGIYATLKSASR 55 >UniRef50_Q7S386 Cluster: Putative uncharacterized protein NCU04859.1; n=1; Neurospora crassa|Rep: Putative uncharacterized protein NCU04859.1 - Neurospora crassa Length = 1327 Score = 44.8 bits (101), Expect = 0.002 Identities = 19/37 (51%), Positives = 29/37 (78%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTL 454 +A + ++ +VV TGAGIST++GIPDFR NG+++L Sbjct: 17 IANSLYKARKVVVITGAGISTNSGIPDFRSENGLYSL 53 >UniRef50_Q6CB00 Cluster: Similarities with tr|Q9UR39 Schizosaccharomyces pombe HST4P; n=1; Yarrowia lipolytica|Rep: Similarities with tr|Q9UR39 Schizosaccharomyces pombe HST4P - Yarrowia lipolytica (Candida lipolytica) Length = 721 Score = 44.8 bits (101), Expect = 0.002 Identities = 27/65 (41%), Positives = 39/65 (60%), Gaps = 2/65 (3%) Frame = +2 Query: 314 NDKLNQKCV-LLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW-TLEKEGKKPTINV 487 N +N+K + LL + +S+ +VV TGAGIS AGIPDFR G++ +L+ E T Sbjct: 157 NSDINRKDLELLHHVFHNSQRLVVITGAGISVHAGIPDFRSDKGLFVSLKDEYNLKTTGK 216 Query: 488 SFADA 502 + DA Sbjct: 217 ALFDA 221 >UniRef50_Q0CR31 Cluster: NAD-dependent histone deacetylase SIR2; n=2; Pezizomycotina|Rep: NAD-dependent histone deacetylase SIR2 - Aspergillus terreus (strain NIH 2624) Length = 1068 Score = 44.8 bits (101), Expect = 0.002 Identities = 24/50 (48%), Positives = 33/50 (66%), Gaps = 2/50 (4%) Frame = +2 Query: 287 LGVPEKFDSNDKLNQKCVL--LAQLVKDSKHIVVHTGAGISTSAGIPDFR 430 + + +F KL Q + +L+++SK+IVV TGAGISTS GIPDFR Sbjct: 148 IAISREFSRRPKLPQYNSIDDAVKLLQESKNIVVLTGAGISTSLGIPDFR 197 >UniRef50_A6RSV6 Cluster: Putative uncharacterized protein; n=2; Sclerotiniaceae|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 1195 Score = 44.8 bits (101), Expect = 0.002 Identities = 18/37 (48%), Positives = 29/37 (78%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTL 454 +A ++ S+ +VV TGAGIST+ GIPDFR +G++++ Sbjct: 17 IADILAKSRKVVVVTGAGISTNVGIPDFRSEHGLYSM 53 >UniRef50_Q0LIC7 Cluster: Silent information regulator protein Sir2; n=2; Bacteria|Rep: Silent information regulator protein Sir2 - Herpetosiphon aurantiacus ATCC 23779 Length = 244 Score = 44.4 bits (100), Expect = 0.003 Identities = 18/27 (66%), Positives = 23/27 (85%) Frame = +2 Query: 368 KHIVVHTGAGISTSAGIPDFRGPNGVW 448 ++IVV TGAGIS ++G+ FRGPNGVW Sbjct: 11 RNIVVLTGAGISVASGVRPFRGPNGVW 37 >UniRef50_A6DES9 Cluster: Transcriptional regulator, Sir2 family protein; n=2; Epsilonproteobacteria|Rep: Transcriptional regulator, Sir2 family protein - Caminibacter mediatlanticus TB-2 Length = 264 Score = 44.4 bits (100), Expect = 0.003 Identities = 18/48 (37%), Positives = 29/48 (60%) Frame = +2 Query: 341 LLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTIN 484 L A +K++K++++ GAG+ +G+PDFRG G W KK +N Sbjct: 6 LAANEIKNAKYLLITAGAGMGVDSGLPDFRGNEGFWRAYPIAKKLGLN 53 >UniRef50_Q6CQA7 Cluster: Kluyveromyces lactis strain NRRL Y-1140 chromosome D of strain NRRL Y- 1140 of Kluyveromyces lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces lactis strain NRRL Y-1140 chromosome D of strain NRRL Y- 1140 of Kluyveromyces lactis - Kluyveromyces lactis (Yeast) (Candida sphaerica) Length = 399 Score = 44.4 bits (100), Expect = 0.003 Identities = 21/39 (53%), Positives = 27/39 (69%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEK 460 L ++ SK IVV GAG+S +AGIPDFR NG++T K Sbjct: 105 LTYVLSYSKRIVVVQGAGVSVAAGIPDFRSANGLFTTLK 143 >UniRef50_Q0UNC9 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 479 Score = 44.4 bits (100), Expect = 0.003 Identities = 19/31 (61%), Positives = 26/31 (83%) Frame = +2 Query: 347 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPN 439 A+L+++ K+I++ TGAGISTS GIPDFR N Sbjct: 167 AKLLRERKNIMIITGAGISTSLGIPDFRSKN 197 >UniRef50_A6RXY5 Cluster: Putative uncharacterized protein; n=2; Pezizomycotina|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 446 Score = 44.4 bits (100), Expect = 0.003 Identities = 20/24 (83%), Positives = 22/24 (91%) Frame = +2 Query: 365 SKHIVVHTGAGISTSAGIPDFRGP 436 +K+IVV TGAGISTSAGIPDFR P Sbjct: 36 AKNIVVMTGAGISTSAGIPDFRSP 59 >UniRef50_A1DG07 Cluster: SIR2 family histone deacetylase, putative; n=3; Trichocomaceae|Rep: SIR2 family histone deacetylase, putative - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 425 Score = 44.4 bits (100), Expect = 0.003 Identities = 20/27 (74%), Positives = 22/27 (81%) Frame = +2 Query: 359 KDSKHIVVHTGAGISTSAGIPDFRGPN 439 KD + IVV GAGISTSAGIPDFR P+ Sbjct: 33 KDVRRIVVMVGAGISTSAGIPDFRSPD 59 >UniRef50_Q88ZA0 Cluster: NAD-dependent deacetylase; n=4; Lactobacillus|Rep: NAD-dependent deacetylase - Lactobacillus plantarum Length = 234 Score = 44.4 bits (100), Expect = 0.003 Identities = 17/32 (53%), Positives = 26/32 (81%) Frame = +2 Query: 356 VKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 451 ++ ++HIV TGAG+ST +GIPD+R NG++T Sbjct: 11 LQQAQHIVFMTGAGVSTPSGIPDYRSKNGLYT 42 >UniRef50_UPI000023F1DF Cluster: hypothetical protein FG02466.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG02466.1 - Gibberella zeae PH-1 Length = 1569 Score = 44.0 bits (99), Expect = 0.004 Identities = 22/34 (64%), Positives = 28/34 (82%) Frame = +2 Query: 353 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTL 454 L+K K IVV TGAGIST++GIPDFR NG+++L Sbjct: 638 LLKARKVIVV-TGAGISTNSGIPDFRSENGLYSL 670 >UniRef50_A7HL19 Cluster: Silent information regulator protein Sir2; n=1; Fervidobacterium nodosum Rt17-B1|Rep: Silent information regulator protein Sir2 - Fervidobacterium nodosum Rt17-B1 Length = 244 Score = 44.0 bits (99), Expect = 0.004 Identities = 19/41 (46%), Positives = 28/41 (68%) Frame = +2 Query: 329 QKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 451 ++ + L +K+SK V TGAG+S +GIPDFR NGV++ Sbjct: 2 EEILTLVSWLKNSKFTTVLTGAGVSVPSGIPDFRSKNGVYS 42 >UniRef50_A4JS80 Cluster: Silent information regulator protein Sir2; n=1; Burkholderia vietnamiensis G4|Rep: Silent information regulator protein Sir2 - Burkholderia vietnamiensis (strain G4 / LMG 22486) (Burkholderiacepacia (strain R1808)) Length = 274 Score = 44.0 bits (99), Expect = 0.004 Identities = 17/35 (48%), Positives = 24/35 (68%) Frame = +2 Query: 347 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 451 A + D+ IV+ GAG+S +G+PDFRG G+WT Sbjct: 11 ADWIADADGIVIAAGAGMSVDSGLPDFRGTGGLWT 45 >UniRef50_Q875P9 Cluster: HST1; n=1; Lachancea kluyveri|Rep: HST1 - Saccharomyces kluyveri (Yeast) (Saccharomyces silvestris) Length = 414 Score = 44.0 bits (99), Expect = 0.004 Identities = 28/78 (35%), Positives = 41/78 (52%) Frame = +2 Query: 218 DKLSPKNVLQLCKGLSPYENKGILGVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAG 397 D L ++ ++L K L NK +L K + L A +K ++ ++V TGAG Sbjct: 39 DPLEKRHAVRLIKDLQKAMNK-VLSTRIKLANFHTLEH----FAAKLKTARRVLVLTGAG 93 Query: 398 ISTSAGIPDFRGPNGVWT 451 ISTS GIPDFR G ++ Sbjct: 94 ISTSLGIPDFRSSEGFYS 111 >UniRef50_Q7S6G9 Cluster: Putative uncharacterized protein NCU04737.1; n=3; Sordariomycetes|Rep: Putative uncharacterized protein NCU04737.1 - Neurospora crassa Length = 670 Score = 44.0 bits (99), Expect = 0.004 Identities = 20/27 (74%), Positives = 24/27 (88%) Frame = +2 Query: 350 QLVKDSKHIVVHTGAGISTSAGIPDFR 430 +L+K SK+I+V TGAGISTS GIPDFR Sbjct: 201 ELLKRSKNIIVLTGAGISTSLGIPDFR 227 >UniRef50_Q6C8V5 Cluster: Similar to tr|Q9FY91 Arabidopsis thaliana SIR2-family protein; n=1; Yarrowia lipolytica|Rep: Similar to tr|Q9FY91 Arabidopsis thaliana SIR2-family protein - Yarrowia lipolytica (Candida lipolytica) Length = 411 Score = 44.0 bits (99), Expect = 0.004 Identities = 21/60 (35%), Positives = 38/60 (63%) Frame = +2 Query: 359 KDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFADAQPQKPI*F*KSW 538 K++K ++ TGAGIST++G+PD+RGP G +T +PT+ F + ++ + ++W Sbjct: 46 KNTKTAIL-TGAGISTASGLPDYRGPTGTYT-TNPNHQPTLYHEFVSDEHKRKRYWSRAW 103 >UniRef50_Q4WT50 Cluster: SIR2 family histone deacetylase (Hst4), putative; n=7; Trichocomaceae|Rep: SIR2 family histone deacetylase (Hst4), putative - Aspergillus fumigatus (Sartorya fumigata) Length = 614 Score = 44.0 bits (99), Expect = 0.004 Identities = 22/42 (52%), Positives = 32/42 (76%), Gaps = 1/42 (2%) Frame = +2 Query: 341 LLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW-TLEKE 463 LL + ++ + IVV GAGISTSAGIPDFR +G++ +L+K+ Sbjct: 125 LLVKTLRRHRKIVVIAGAGISTSAGIPDFRSTDGLFKSLQKK 166 >UniRef50_Q5L014 Cluster: NAD-dependent deacetylase 1; n=7; Bacillaceae|Rep: NAD-dependent deacetylase 1 - Geobacillus kaustophilus Length = 242 Score = 44.0 bits (99), Expect = 0.004 Identities = 20/44 (45%), Positives = 28/44 (63%), Gaps = 1/44 (2%) Frame = +2 Query: 365 SKHIVVHTGAGISTSAGIPDFRGP-NGVWTLEKEGKKPTINVSF 493 S+H VV TGAG+ST +G+PDFR P G+W + TI+ + Sbjct: 10 SRHTVVLTGAGMSTESGLPDFRSPRTGLWARFNPSELATIDALY 53 >UniRef50_A1ZPG8 Cluster: NAD-dependent deacetylase; n=1; Microscilla marina ATCC 23134|Rep: NAD-dependent deacetylase - Microscilla marina ATCC 23134 Length = 278 Score = 43.6 bits (98), Expect = 0.005 Identities = 19/46 (41%), Positives = 26/46 (56%) Frame = +2 Query: 338 VLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKP 475 +L AQ + K I TGAGIS +G+P +RG +G+W KP Sbjct: 10 LLCAQALAQDKLITFLTGAGISAESGVPTYRGTDGIWVEGSRNYKP 55 >UniRef50_Q7SCL4 Cluster: Putative uncharacterized protein NCU00523.1; n=2; Pezizomycotina|Rep: Putative uncharacterized protein NCU00523.1 - Neurospora crassa Length = 1220 Score = 43.6 bits (98), Expect = 0.005 Identities = 29/83 (34%), Positives = 42/83 (50%), Gaps = 7/83 (8%) Frame = +2 Query: 284 ILGVPEKFDSNDKLNQKCVLLAQLVKDSK--HIVVHTGAGISTSAGIPDFRGP-NGVW-- 448 + VPE + + +A +K K +VV TGAGIST+AGIPDFR P G++ Sbjct: 848 VSAVPETTKPENLSERSLPAVADYIKSGKARKVVVLTGAGISTAAGIPDFRSPETGLYAN 907 Query: 449 --TLEKEGKKPTINVSFADAQPQ 511 LE E + ++ F P+ Sbjct: 908 LAALELEEPEDVFSLPFFKENPK 930 >UniRef50_A1HLU5 Cluster: Silent information regulator protein Sir2; n=1; Thermosinus carboxydivorans Nor1|Rep: Silent information regulator protein Sir2 - Thermosinus carboxydivorans Nor1 Length = 261 Score = 43.2 bits (97), Expect = 0.006 Identities = 17/35 (48%), Positives = 25/35 (71%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 +A + + +IVV TGAG+ST +G+PDFR G+W Sbjct: 9 IAAAWRSANNIVVFTGAGMSTESGLPDFRSKQGLW 43 >UniRef50_A7TQE2 Cluster: Putative uncharacterized protein; n=1; Vanderwaltozyma polyspora DSM 70294|Rep: Putative uncharacterized protein - Vanderwaltozyma polyspora DSM 70294 Length = 602 Score = 43.2 bits (97), Expect = 0.006 Identities = 19/32 (59%), Positives = 24/32 (75%) Frame = +2 Query: 356 VKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 451 +K +K I+V TGAGISTS GIPDFR G ++ Sbjct: 263 LKSAKKIIVLTGAGISTSLGIPDFRSSEGFYS 294 >UniRef50_A2QFF9 Cluster: Complex: Sir2p is one of four Silent Information Regulator genes in yeast. Sir2p; n=6; Pezizomycotina|Rep: Complex: Sir2p is one of four Silent Information Regulator genes in yeast. Sir2p - Aspergillus niger Length = 378 Score = 43.2 bits (97), Expect = 0.006 Identities = 24/56 (42%), Positives = 34/56 (60%), Gaps = 5/56 (8%) Frame = +2 Query: 359 KDSKHIVVHTGAGISTSAGIPDFRGPN-GVWT----LEKEGKKPTINVSFADAQPQ 511 K K +VV GAGISTSAGIPDFR P+ G+++ L+ + ++SF P+ Sbjct: 33 KPVKRVVVMVGAGISTSAGIPDFRSPDTGIYSNLAHLDLPDPEAVFDISFFRQNPR 88 >UniRef50_Q5V4Q5 Cluster: NAD-dependent deacetylase; n=2; Halobacteriaceae|Rep: NAD-dependent deacetylase - Haloarcula marismortui (Halobacterium marismortui) Length = 260 Score = 43.2 bits (97), Expect = 0.006 Identities = 16/35 (45%), Positives = 27/35 (77%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 +A+ ++ ++ V TGAG+ST++GIP FRG +G+W Sbjct: 19 VAEALRTAETAVALTGAGVSTASGIPSFRGDDGIW 53 >UniRef50_Q011Q8 Cluster: NAD-dependent deacetylase SIRT2; n=2; Ostreococcus|Rep: NAD-dependent deacetylase SIRT2 - Ostreococcus tauri Length = 394 Score = 42.7 bits (96), Expect = 0.008 Identities = 18/28 (64%), Positives = 24/28 (85%) Frame = +2 Query: 365 SKHIVVHTGAGISTSAGIPDFRGPNGVW 448 +K++VV TGAGIS SAGIPDFR +G++ Sbjct: 103 AKNVVVMTGAGISVSAGIPDFRSESGLY 130 >UniRef50_Q6BPH5 Cluster: Debaryomyces hansenii chromosome E of strain CBS767 of Debaryomyces hansenii; n=2; Saccharomycetaceae|Rep: Debaryomyces hansenii chromosome E of strain CBS767 of Debaryomyces hansenii - Debaryomyces hansenii (Yeast) (Torulaspora hansenii) Length = 573 Score = 42.7 bits (96), Expect = 0.008 Identities = 19/32 (59%), Positives = 24/32 (75%) Frame = +2 Query: 356 VKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 451 +K +K I+V TGAGISTS GIPDFR G ++ Sbjct: 257 IKKAKKILVVTGAGISTSLGIPDFRSSKGFYS 288 >UniRef50_Q0UMU7 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 670 Score = 42.7 bits (96), Expect = 0.008 Identities = 24/54 (44%), Positives = 32/54 (59%), Gaps = 1/54 (1%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW-TLEKEGKKPTINVSFADA 502 L ++ + IVV GAGIS SAGIPDFR G++ +L+KE K + DA Sbjct: 117 LLNVLHKKRKIVVIAGAGISVSAGIPDFRSATGLFNSLKKEHKLKSSGKDLFDA 170 >UniRef50_O94066 Cluster: Transcription regulatory protein; n=6; Saccharomycetales|Rep: Transcription regulatory protein - Candida albicans (Yeast) Length = 331 Score = 42.7 bits (96), Expect = 0.008 Identities = 18/32 (56%), Positives = 23/32 (71%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPN 439 +A+ VK+ K + GAGIST AGIPDFR P+ Sbjct: 11 VAEAVKNGKKVTFFNGAGISTGAGIPDFRSPD 42 >UniRef50_Q96EB6 Cluster: NAD-dependent deacetylase sirtuin-1; n=29; Euteleostomi|Rep: NAD-dependent deacetylase sirtuin-1 - Homo sapiens (Human) Length = 747 Score = 42.7 bits (96), Expect = 0.008 Identities = 17/33 (51%), Positives = 26/33 (78%) Frame = +2 Query: 350 QLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 +L+++ K I+V TGAG+S S GIPDFR +G++ Sbjct: 248 KLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIY 280 >UniRef50_Q9UR39 Cluster: NAD-dependent deacetylase hst4; n=1; Schizosaccharomyces pombe|Rep: NAD-dependent deacetylase hst4 - Schizosaccharomyces pombe (Fission yeast) Length = 415 Score = 42.7 bits (96), Expect = 0.008 Identities = 19/36 (52%), Positives = 25/36 (69%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 451 L ++ +K IVV TGAGIS AGIPDFR G+++ Sbjct: 50 LVSAIRKAKRIVVVTGAGISCDAGIPDFRSSEGLFS 85 >UniRef50_A4J646 Cluster: Silent information regulator protein Sir2; n=2; Peptococcaceae|Rep: Silent information regulator protein Sir2 - Desulfotomaculum reducens MI-1 Length = 256 Score = 42.3 bits (95), Expect = 0.011 Identities = 19/36 (52%), Positives = 25/36 (69%), Gaps = 1/36 (2%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPN-GVW 448 L +L+K + + TGAGIST +GIPDFR N G+W Sbjct: 10 LTELIKKAGKTIALTGAGISTESGIPDFRSKNTGLW 45 >UniRef50_A1HU63 Cluster: Silent information regulator protein Sir2; n=1; Thermosinus carboxydivorans Nor1|Rep: Silent information regulator protein Sir2 - Thermosinus carboxydivorans Nor1 Length = 243 Score = 42.3 bits (95), Expect = 0.011 Identities = 18/34 (52%), Positives = 25/34 (73%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGV 445 L + ++ + H V TGAGIST++GIPDFRG N + Sbjct: 10 LVECLRAANHATVLTGAGISTASGIPDFRGINRI 43 >UniRef50_A7RMK8 Cluster: Predicted protein; n=5; Eumetazoa|Rep: Predicted protein - Nematostella vectensis Length = 273 Score = 42.3 bits (95), Expect = 0.011 Identities = 18/35 (51%), Positives = 24/35 (68%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 L L+ +K+I+ TGAGIS +GIP FRG G+W Sbjct: 18 LKDLLSKAKNILFLTGAGISAESGIPTFRGAGGLW 52 >UniRef50_A0D0F1 Cluster: Chromosome undetermined scaffold_33, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_33, whole genome shotgun sequence - Paramecium tetraurelia Length = 264 Score = 42.3 bits (95), Expect = 0.011 Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 5/60 (8%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTL-----EKEGKKPTINVSFADAQP 508 + + +K+ + ++ GAG+ +G+PDFRG G WT+ K G N SF D P Sbjct: 1 MQKYIKECQAFIITAGAGMGVDSGLPDFRGNKGFWTVYRPFENKFGFTDCANPSFMDYNP 60 >UniRef50_Q6BPA4 Cluster: Debaryomyces hansenii chromosome E of strain CBS767 of Debaryomyces hansenii; n=6; Saccharomycetales|Rep: Debaryomyces hansenii chromosome E of strain CBS767 of Debaryomyces hansenii - Debaryomyces hansenii (Yeast) (Torulaspora hansenii) Length = 438 Score = 42.3 bits (95), Expect = 0.011 Identities = 21/50 (42%), Positives = 35/50 (70%) Frame = +2 Query: 311 SNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEK 460 SN+++ K +++++ S+ VV TGAGIS +AGIPDFR +G++ + K Sbjct: 12 SNEQI--KLSEVSKIIFKSRKAVVLTGAGISCNAGIPDFRSSDGLYNMVK 59 >UniRef50_A5DSX8 Cluster: NAD-dependent histone deacetylase SIR2; n=1; Lodderomyces elongisporus NRRL YB-4239|Rep: NAD-dependent histone deacetylase SIR2 - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 568 Score = 42.3 bits (95), Expect = 0.011 Identities = 19/34 (55%), Positives = 25/34 (73%) Frame = +2 Query: 353 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTL 454 L++ S I+V TGAGISTS GIPDFR G +++ Sbjct: 252 LIQKSHKILVITGAGISTSLGIPDFRSSQGFYSM 285 >UniRef50_A4RMS1 Cluster: Putative uncharacterized protein; n=2; Sordariomycetes|Rep: Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 666 Score = 42.3 bits (95), Expect = 0.011 Identities = 18/35 (51%), Positives = 26/35 (74%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 L ++++ K IV+ GAGIS SAGIPDFR +G++ Sbjct: 132 LTKVLRKKKRIVIIAGAGISVSAGIPDFRSQSGLF 166 >UniRef50_Q5KPC9 Cluster: Hst3 protein, putative; n=2; Filobasidiella neoformans|Rep: Hst3 protein, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 389 Score = 41.9 bits (94), Expect = 0.015 Identities = 19/36 (52%), Positives = 26/36 (72%) Frame = +2 Query: 356 VKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKE 463 V ++ IV +GAGIS S+GIPDFR G+++L KE Sbjct: 32 VAKARRIVTVSGAGISCSSGIPDFRSEGGLYSLVKE 67 >UniRef50_Q4PG00 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 596 Score = 41.9 bits (94), Expect = 0.015 Identities = 19/40 (47%), Positives = 28/40 (70%), Gaps = 1/40 (2%) Frame = +2 Query: 353 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT-LEKEGK 469 L+ K I++ +GAGIS S GIPDFR +G++ L+ EG+ Sbjct: 186 LLSTRKRIMILSGAGISVSCGIPDFRSKDGIYAILQSEGQ 225 >UniRef50_A5DNV7 Cluster: Putative uncharacterized protein; n=1; Pichia guilliermondii|Rep: Putative uncharacterized protein - Pichia guilliermondii (Yeast) (Candida guilliermondii) Length = 403 Score = 41.9 bits (94), Expect = 0.015 Identities = 24/59 (40%), Positives = 35/59 (59%), Gaps = 1/59 (1%) Frame = +2 Query: 353 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT-LEKEGKKPTINVSFADAQPQKPI*F 526 +++ +K I+V TGAGISTS GIPDFR G+++ L + G + V D + P F Sbjct: 112 VLEKAKKILVVTGAGISTSLGIPDFRSFQGIYSQLSRSGLENAQQVFHIDRFCKDPTLF 170 >UniRef50_Q9NXA8 Cluster: NAD-dependent deacetylase sirtuin-5; n=28; Coelomata|Rep: NAD-dependent deacetylase sirtuin-5 - Homo sapiens (Human) Length = 310 Score = 41.9 bits (94), Expect = 0.015 Identities = 15/28 (53%), Positives = 21/28 (75%) Frame = +2 Query: 365 SKHIVVHTGAGISTSAGIPDFRGPNGVW 448 +KHIV+ +GAG+S +G+P FRG G W Sbjct: 50 AKHIVIISGAGVSAESGVPTFRGAGGYW 77 >UniRef50_Q97MB4 Cluster: NAD-dependent deacetylase; n=7; Bacteria|Rep: NAD-dependent deacetylase - Clostridium acetobutylicum Length = 245 Score = 41.9 bits (94), Expect = 0.015 Identities = 21/53 (39%), Positives = 31/53 (58%) Frame = +2 Query: 317 DKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKP 475 DK+N+ L ++V +S IV GAG+ST + IPDFR NG++ + P Sbjct: 5 DKINE----LKKIVAESSSIVFFGGAGVSTESNIPDFRSENGLYKTKNNFSYP 53 >UniRef50_A6Q2C0 Cluster: Transcriptional regulator, Sir2 family; n=2; Bacteria|Rep: Transcriptional regulator, Sir2 family - Nitratiruptor sp. (strain SB155-2) Length = 268 Score = 41.5 bits (93), Expect = 0.019 Identities = 15/40 (37%), Positives = 25/40 (62%) Frame = +2 Query: 353 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKK 472 L+K + ++++ GAG+ +G+PDFRG +G W KK Sbjct: 8 LIKQADYLLITAGAGMGVDSGLPDFRGVHGFWRAYPAAKK 47 >UniRef50_A4JJP4 Cluster: Silent information regulator protein Sir2; n=1; Burkholderia vietnamiensis G4|Rep: Silent information regulator protein Sir2 - Burkholderia vietnamiensis (strain G4 / LMG 22486) (Burkholderiacepacia (strain R1808)) Length = 273 Score = 41.5 bits (93), Expect = 0.019 Identities = 14/35 (40%), Positives = 24/35 (68%) Frame = +2 Query: 347 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 451 A + ++ +++ GAG+S +G+PDFRG G+WT Sbjct: 12 ASWIANADALIIAAGAGMSVDSGLPDFRGSQGIWT 46 >UniRef50_A3JEV2 Cluster: NAD-dependent deacetylase; n=2; Marinobacter|Rep: NAD-dependent deacetylase - Marinobacter sp. ELB17 Length = 300 Score = 41.5 bits (93), Expect = 0.019 Identities = 16/40 (40%), Positives = 25/40 (62%) Frame = +2 Query: 329 QKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 Q +LA + +++ TGAG+ST +GIPD+R +G W Sbjct: 31 QAGAMLADYIHSHPRLLILTGAGVSTDSGIPDYRDGDGAW 70 >UniRef50_Q4QB33 Cluster: Sir2-family protein-like protein; n=4; Trypanosomatidae|Rep: Sir2-family protein-like protein - Leishmania major Length = 320 Score = 41.5 bits (93), Expect = 0.019 Identities = 18/28 (64%), Positives = 21/28 (75%) Frame = +2 Query: 359 KDSKHIVVHTGAGISTSAGIPDFRGPNG 442 K + VV TGAG ST +GIPD+RGPNG Sbjct: 18 KRGRGCVVLTGAGCSTESGIPDYRGPNG 45 >UniRef50_Q2H5A0 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 387 Score = 41.5 bits (93), Expect = 0.019 Identities = 18/24 (75%), Positives = 21/24 (87%) Frame = +2 Query: 365 SKHIVVHTGAGISTSAGIPDFRGP 436 ++ IVV TGAGIST+AGIPDFR P Sbjct: 34 ARRIVVMTGAGISTAAGIPDFRSP 57 >UniRef50_O94640 Cluster: NAD-dependent histone deacetylase sir2; n=1; Schizosaccharomyces pombe|Rep: NAD-dependent histone deacetylase sir2 - Schizosaccharomyces pombe (Fission yeast) Length = 475 Score = 41.5 bits (93), Expect = 0.019 Identities = 19/35 (54%), Positives = 25/35 (71%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 + L+K +K++VV GAGISTS GI DFR NG + Sbjct: 149 VVNLLKKAKNVVVLVGAGISTSLGILDFRSDNGFY 183 >UniRef50_UPI0000E49AD8 Cluster: PREDICTED: similar to NAD-dependent deacetylase sirtuin 2 homolog; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to NAD-dependent deacetylase sirtuin 2 homolog - Strongylocentrotus purpuratus Length = 400 Score = 41.1 bits (92), Expect = 0.025 Identities = 19/33 (57%), Positives = 25/33 (75%), Gaps = 2/33 (6%) Frame = +2 Query: 344 LAQLVKDSK--HIVVHTGAGISTSAGIPDFRGP 436 +A +K+ K ++V +GAGISTSAGIPDFR P Sbjct: 64 IADFIKEGKCKKVIVMSGAGISTSAGIPDFRTP 96 >UniRef50_Q6C219 Cluster: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica; n=1; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 320 Score = 41.1 bits (92), Expect = 0.025 Identities = 23/53 (43%), Positives = 35/53 (66%) Frame = +2 Query: 290 GVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 G E ++ K++ LL +L + +++IVV GAGISTS GIPDFR +G++ Sbjct: 36 GDVESLAAHSKIHTFGDLLREL-ETAQNIVVLCGAGISTSLGIPDFRSADGLY 87 >UniRef50_A4QUX8 Cluster: Putative uncharacterized protein; n=1; Magnaporthe grisea|Rep: Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 460 Score = 41.1 bits (92), Expect = 0.025 Identities = 24/53 (45%), Positives = 33/53 (62%), Gaps = 5/53 (9%) Frame = +2 Query: 368 KHIVVHTGAGISTSAGIPDFRGP-NGVWTLEKEGKKP----TINVSFADAQPQ 511 K I V TGAGIST+AGIPDFR P G+++ + K P ++SF +P+ Sbjct: 40 KRITVMTGAGISTAAGIPDFRSPGTGLYSNLERLKLPEPEAVFDISFFRDRPE 92 >UniRef50_A1ZHW6 Cluster: NAD-dependent deacetylase; n=2; Microscilla marina ATCC 23134|Rep: NAD-dependent deacetylase - Microscilla marina ATCC 23134 Length = 279 Score = 40.7 bits (91), Expect = 0.034 Identities = 18/38 (47%), Positives = 22/38 (57%) Frame = +2 Query: 362 DSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKP 475 D +VV TGAGIS +GIP FRG G W + +P Sbjct: 17 DQAKMVVLTGAGISAESGIPTFRGKEGYWKIGSVNYQP 54 >UniRef50_Q7QZ36 Cluster: GLP_464_21655_23334; n=1; Giardia lamblia ATCC 50803|Rep: GLP_464_21655_23334 - Giardia lamblia ATCC 50803 Length = 559 Score = 40.7 bits (91), Expect = 0.034 Identities = 22/55 (40%), Positives = 34/55 (61%), Gaps = 4/55 (7%) Frame = +2 Query: 356 VKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT-LEKEG-KKPT--INVSFADAQP 508 ++ ++ ++ GAGIS SAGIPDFR NG++ L++ +KPT N+ F P Sbjct: 160 LRRARKVIFLVGAGISVSAGIPDFRSKNGIYNRLQQYNLQKPTDMFNLDFFRGNP 214 >UniRef50_Q2HG51 Cluster: Putative uncharacterized protein; n=2; Pezizomycotina|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 594 Score = 40.7 bits (91), Expect = 0.034 Identities = 24/54 (44%), Positives = 29/54 (53%), Gaps = 1/54 (1%) Frame = +2 Query: 356 VKDSKHIVVHTGAGISTSAGIPDFRGPNGVW-TLEKEGKKPTINVSFADAQPQK 514 ++ K IVV GAGIS SAGIPDFR G++ TL + K DA K Sbjct: 46 LRKKKKIVVIAGAGISVSAGIPDFRSSTGLFATLRGQHKLKASGKHLFDASVYK 99 >UniRef50_Q899G3 Cluster: NAD-dependent deacetylase; n=19; cellular organisms|Rep: NAD-dependent deacetylase - Clostridium tetani Length = 247 Score = 40.7 bits (91), Expect = 0.034 Identities = 17/35 (48%), Positives = 24/35 (68%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 L +L+K S +IV GAG+ST + IPDFR G++ Sbjct: 7 LKELIKSSSNIVFFGGAGVSTESNIPDFRSEEGLY 41 >UniRef50_Q81NT6 Cluster: NAD-dependent deacetylase; n=11; Bacillus cereus group|Rep: NAD-dependent deacetylase - Bacillus anthracis Length = 242 Score = 40.7 bits (91), Expect = 0.034 Identities = 17/32 (53%), Positives = 24/32 (75%) Frame = +2 Query: 353 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 +++ +K I V TGAG ST +GIPDFR NG++ Sbjct: 10 ILEKAKKITVLTGAGASTESGIPDFRSANGLY 41 >UniRef50_UPI0000D578DC Cluster: PREDICTED: similar to sirtuin 5 (silent mating type information regulation 2 homolog) 5; n=1; Tribolium castaneum|Rep: PREDICTED: similar to sirtuin 5 (silent mating type information regulation 2 homolog) 5 - Tribolium castaneum Length = 254 Score = 40.3 bits (90), Expect = 0.044 Identities = 16/33 (48%), Positives = 23/33 (69%) Frame = +2 Query: 350 QLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 ++V ++ IV TGAG+S +GIP FRG G+W Sbjct: 14 RVVSQARSIVALTGAGVSAESGIPVFRGAGGLW 46 >UniRef50_Q21KQ1 Cluster: Silent information regulator protein Sir2; n=2; Gammaproteobacteria|Rep: Silent information regulator protein Sir2 - Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) Length = 235 Score = 40.3 bits (90), Expect = 0.044 Identities = 17/30 (56%), Positives = 21/30 (70%) Frame = +2 Query: 359 KDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 KD K IVV TGAG+S +G+ FR NG+W Sbjct: 5 KDYKRIVVLTGAGVSAESGLKTFRDNNGLW 34 >UniRef50_Q046W9 Cluster: NAD-dependent protein deacetylase, SIR2 family; n=6; Lactobacillus|Rep: NAD-dependent protein deacetylase, SIR2 family - Lactobacillus gasseri (strain ATCC 33323 / DSM 20243) Length = 237 Score = 40.3 bits (90), Expect = 0.044 Identities = 19/64 (29%), Positives = 33/64 (51%) Frame = +2 Query: 323 LNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFADA 502 LN + L + ++ H+ TGAG+ST + IPD+R NG++ E + ++ Sbjct: 3 LNNQIAALQADLNNAHHVTYLTGAGVSTPSHIPDYRSKNGIYNGISESPEQILSEDTLFH 62 Query: 503 QPQK 514 +P K Sbjct: 63 EPAK 66 >UniRef50_A6WG46 Cluster: Silent information regulator protein Sir2; n=4; Actinomycetales|Rep: Silent information regulator protein Sir2 - Kineococcus radiotolerans SRS30216 Length = 279 Score = 40.3 bits (90), Expect = 0.044 Identities = 19/33 (57%), Positives = 24/33 (72%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNG 442 LA L+ D +VV GAG+ST +GIPD+RGP G Sbjct: 7 LADLL-DGGRVVVLEGAGMSTGSGIPDYRGPGG 38 >UniRef50_Q1EP52 Cluster: Transcriptional regulator Sir2 family protein; n=1; Musa balbisiana|Rep: Transcriptional regulator Sir2 family protein - Musa balbisiana (Banana) Length = 217 Score = 40.3 bits (90), Expect = 0.044 Identities = 18/30 (60%), Positives = 23/30 (76%) Frame = +2 Query: 341 LLAQLVKDSKHIVVHTGAGISTSAGIPDFR 430 LL Q + S+ +VV TGAGIST +GIPD+R Sbjct: 175 LLYQFIDTSRKLVVLTGAGISTESGIPDYR 204 >UniRef50_Q54QE6 Cluster: Zn finger-containing protein; n=5; Eukaryota|Rep: Zn finger-containing protein - Dictyostelium discoideum AX4 Length = 512 Score = 40.3 bits (90), Expect = 0.044 Identities = 17/23 (73%), Positives = 20/23 (86%) Frame = +2 Query: 368 KHIVVHTGAGISTSAGIPDFRGP 436 K+I+V TGAGIS +AGIPDFR P Sbjct: 251 KNIIVMTGAGISVAAGIPDFRSP 273 >UniRef50_Q9USN7 Cluster: Sir2 family histone deacetylase Hst2; n=1; Schizosaccharomyces pombe|Rep: Sir2 family histone deacetylase Hst2 - Schizosaccharomyces pombe (Fission yeast) Length = 332 Score = 40.3 bits (90), Expect = 0.044 Identities = 20/33 (60%), Positives = 24/33 (72%), Gaps = 2/33 (6%) Frame = +2 Query: 344 LAQLVKDSK--HIVVHTGAGISTSAGIPDFRGP 436 +A L+K+ K I V GAGIST+AGIPDFR P Sbjct: 18 VASLIKEGKVKKICVMVGAGISTAAGIPDFRSP 50 >UniRef50_Q5KG84 Cluster: Hst4 protein, putative; n=2; Filobasidiella neoformans|Rep: Hst4 protein, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 478 Score = 40.3 bits (90), Expect = 0.044 Identities = 23/53 (43%), Positives = 36/53 (67%) Frame = +2 Query: 308 DSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEG 466 D D L Q ++A+L + +K IVV +GAG+ST A IPDFR +G+++ + +G Sbjct: 28 DVEDTLRQ---VVARL-RMAKRIVVVSGAGVSTGAAIPDFRSASGLFSGKTKG 76 >UniRef50_A3LRA1 Cluster: Transcriptional regulatory protein; n=2; Saccharomycetales|Rep: Transcriptional regulatory protein - Pichia stipitis (Yeast) Length = 311 Score = 40.3 bits (90), Expect = 0.044 Identities = 16/42 (38%), Positives = 27/42 (64%) Frame = +2 Query: 323 LNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 ++++ V + +K + IV GAG+S S+G+P FRG G+W Sbjct: 1 MSKQLVEFQEYLKTCRKIVALVGAGLSVSSGLPTFRGSQGLW 42 >UniRef50_A1CD03 Cluster: SIR2 family histone deacetylase, putative; n=2; Trichocomaceae|Rep: SIR2 family histone deacetylase, putative - Aspergillus clavatus Length = 329 Score = 40.3 bits (90), Expect = 0.044 Identities = 20/33 (60%), Positives = 24/33 (72%), Gaps = 2/33 (6%) Frame = +2 Query: 344 LAQLVKDS--KHIVVHTGAGISTSAGIPDFRGP 436 +A L+K + IVV GAGIST+AGIPDFR P Sbjct: 7 IATLIKSGQIRRIVVLVGAGISTAAGIPDFRSP 39 >UniRef50_Q67KQ0 Cluster: NAD-dependent deacetylase; n=1; Symbiobacterium thermophilum|Rep: NAD-dependent deacetylase - Symbiobacterium thermophilum Length = 251 Score = 40.3 bits (90), Expect = 0.044 Identities = 16/34 (47%), Positives = 24/34 (70%) Frame = +2 Query: 347 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 A+ ++ S++ V TGAG ST +G+PDFR G+W Sbjct: 9 ARALQASRYAVALTGAGASTESGLPDFRSNTGLW 42 >UniRef50_Q607X6 Cluster: NAD-dependent deacetylase; n=1; Methylococcus capsulatus|Rep: NAD-dependent deacetylase - Methylococcus capsulatus Length = 255 Score = 40.3 bits (90), Expect = 0.044 Identities = 20/37 (54%), Positives = 25/37 (67%), Gaps = 1/37 (2%) Frame = +2 Query: 341 LLAQLVKDSKHIVVHTGAGISTSAGIPDFRGP-NGVW 448 LLA L +D++HI V TGAG+S +GIP FR G W Sbjct: 7 LLASL-RDARHIAVFTGAGVSAESGIPTFRDALTGFW 42 >UniRef50_P53688 Cluster: NAD-dependent histone deacetylase HST4; n=5; Saccharomycetales|Rep: NAD-dependent histone deacetylase HST4 - Saccharomyces cerevisiae (Baker's yeast) Length = 370 Score = 40.3 bits (90), Expect = 0.044 Identities = 18/34 (52%), Positives = 24/34 (70%) Frame = +2 Query: 365 SKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEG 466 SK +VV +GAGIS +AGIPDFR G+++ G Sbjct: 92 SKRMVVVSGAGISVAAGIPDFRSSEGIFSTVNGG 125 >UniRef50_Q3E2I1 Cluster: Silent information regulator protein Sir2; n=7; Bacteria|Rep: Silent information regulator protein Sir2 - Chloroflexus aurantiacus J-10-fl Length = 254 Score = 39.9 bits (89), Expect = 0.059 Identities = 19/47 (40%), Positives = 29/47 (61%), Gaps = 1/47 (2%) Frame = +2 Query: 314 NDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFR-GPNGVWT 451 ND L+ +LA + ++H+ V TGAG+S +GIP FR G+W+ Sbjct: 2 ND-LDDVITILATALSTARHVTVLTGAGVSAESGIPTFRDAQTGLWS 47 >UniRef50_Q22ZC3 Cluster: Transcriptional regulator, Sir2 family protein; n=1; Tetrahymena thermophila SB210|Rep: Transcriptional regulator, Sir2 family protein - Tetrahymena thermophila SB210 Length = 308 Score = 39.9 bits (89), Expect = 0.059 Identities = 19/28 (67%), Positives = 19/28 (67%) Frame = +2 Query: 353 LVKDSKHIVVHTGAGISTSAGIPDFRGP 436 L K K I TGAGIS SAGIPDFR P Sbjct: 63 LAKKYKQIAFLTGAGISVSAGIPDFRSP 90 >UniRef50_A4VDQ9 Cluster: Chromatin regulatory protein sir2; n=1; Tetrahymena thermophila SB210|Rep: Chromatin regulatory protein sir2 - Tetrahymena thermophila SB210 Length = 279 Score = 39.9 bits (89), Expect = 0.059 Identities = 21/36 (58%), Positives = 28/36 (77%), Gaps = 2/36 (5%) Frame = +2 Query: 368 KHIVVHTGAGISTSAGIPDFRGPN-GVWT-LEKEGK 469 K I+V TGAGIST+AGIPDFR + G++ L+K G+ Sbjct: 31 KKIIVLTGAGISTNAGIPDFRSKDTGLYARLKKSGQ 66 >UniRef50_A0DQW0 Cluster: Chromosome undetermined scaffold_6, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_6, whole genome shotgun sequence - Paramecium tetraurelia Length = 367 Score = 39.9 bits (89), Expect = 0.059 Identities = 17/52 (32%), Positives = 31/52 (59%) Frame = +2 Query: 308 DSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKE 463 + N K Q+ + +K++++ GAG+S ++G+P FRG +G WT K+ Sbjct: 101 EQNPKTAQEVTVEQAQKLITKNVLILCGAGLSHASGVPTFRGKDGYWTKGKD 152 >UniRef50_Q6BVM7 Cluster: Similar to CA4170|IPF7784 Candida albicans; n=2; Saccharomycetaceae|Rep: Similar to CA4170|IPF7784 Candida albicans - Debaryomyces hansenii (Yeast) (Torulaspora hansenii) Length = 301 Score = 39.9 bits (89), Expect = 0.059 Identities = 16/28 (57%), Positives = 20/28 (71%) Frame = +2 Query: 365 SKHIVVHTGAGISTSAGIPDFRGPNGVW 448 SK IV GAG+S S+G+P FRG G+W Sbjct: 15 SKRIVALVGAGLSVSSGLPTFRGSQGLW 42 >UniRef50_Q4WFZ3 Cluster: SIR2 family histone deacetylase, putative; n=4; Trichocomaceae|Rep: SIR2 family histone deacetylase, putative - Aspergillus fumigatus (Sartorya fumigata) Length = 403 Score = 39.9 bits (89), Expect = 0.059 Identities = 20/33 (60%), Positives = 24/33 (72%), Gaps = 2/33 (6%) Frame = +2 Query: 344 LAQLVKDSK--HIVVHTGAGISTSAGIPDFRGP 436 +A L+K + IVV GAGIST+AGIPDFR P Sbjct: 83 IANLIKSGQVHKIVVLVGAGISTAAGIPDFRSP 115 >UniRef50_Q7ZVK3 Cluster: NAD-dependent deacetylase sirtuin-2; n=12; Coelomata|Rep: NAD-dependent deacetylase sirtuin-2 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 379 Score = 39.9 bits (89), Expect = 0.059 Identities = 21/40 (52%), Positives = 24/40 (60%) Frame = +2 Query: 317 DKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGP 436 D+L V L K+I+ GAGISTSAGIPDFR P Sbjct: 58 DELTLDSVARYILSGKCKNIICMVGAGISTSAGIPDFRSP 97 >UniRef50_P53687 Cluster: NAD-dependent histone deacetylase HST3; n=6; Saccharomycetales|Rep: NAD-dependent histone deacetylase HST3 - Saccharomyces cerevisiae (Baker's yeast) Length = 447 Score = 39.9 bits (89), Expect = 0.059 Identities = 18/33 (54%), Positives = 24/33 (72%) Frame = +2 Query: 365 SKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKE 463 S+ I TGAGIS +AGIPDFR +G++ L K+ Sbjct: 52 SRRIACLTGAGISCNAGIPDFRSSDGLYDLVKK 84 >UniRef50_UPI00015B48CB Cluster: PREDICTED: similar to 85 kda calcium-independent phospholipase A2 (ipla2); n=1; Nasonia vitripennis|Rep: PREDICTED: similar to 85 kda calcium-independent phospholipase A2 (ipla2) - Nasonia vitripennis Length = 811 Score = 39.5 bits (88), Expect = 0.078 Identities = 20/54 (37%), Positives = 30/54 (55%) Frame = +2 Query: 308 DSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGK 469 D + L +KC+ LA + +V + A IS + IPD+RG NG+W + GK Sbjct: 65 DIPEILEEKCIRLAAAISRETSLV-YIVADISIAVSIPDYRGINGMWARMQLGK 117 >UniRef50_UPI000023E2DA Cluster: hypothetical protein FG00460.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG00460.1 - Gibberella zeae PH-1 Length = 607 Score = 39.5 bits (88), Expect = 0.078 Identities = 19/39 (48%), Positives = 24/39 (61%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEK 460 L ++ K IVV GAGIS +AGIPDFR G++ K Sbjct: 123 LRDTLRKKKKIVVIAGAGISVAAGIPDFRSSTGLFASVK 161 >UniRef50_A6LP94 Cluster: Silent information regulator protein Sir2; n=1; Thermosipho melanesiensis BI429|Rep: Silent information regulator protein Sir2 - Thermosipho melanesiensis BI429 Length = 234 Score = 39.5 bits (88), Expect = 0.078 Identities = 16/31 (51%), Positives = 24/31 (77%) Frame = +2 Query: 356 VKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 + + ++V TGAGISTS+GIPDFR +G++ Sbjct: 8 ILEEGNVVALTGAGISTSSGIPDFRSEDGLY 38 >UniRef50_Q23YS7 Cluster: Transcriptional regulator, Sir2 family protein; n=1; Tetrahymena thermophila SB210|Rep: Transcriptional regulator, Sir2 family protein - Tetrahymena thermophila SB210 Length = 304 Score = 39.5 bits (88), Expect = 0.078 Identities = 13/36 (36%), Positives = 24/36 (66%) Frame = +2 Query: 341 LLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 L+A+ ++ + +++ GAG+ +G+PDFRG G W Sbjct: 8 LIAKRIQSASCLIITAGAGMGVDSGLPDFRGKEGFW 43 >UniRef50_Q4P3S4 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 400 Score = 39.5 bits (88), Expect = 0.078 Identities = 22/55 (40%), Positives = 32/55 (58%), Gaps = 1/55 (1%) Frame = +2 Query: 341 LLAQLVKDSK-HIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFADA 502 L+A+ V +K ++ TGAGIS +GI +RG NG +T+ K +P F DA Sbjct: 27 LVAEFVSAAKGKALIMTGAGISVDSGIAPYRGENGHYTIHKH-YRPIFYHEFVDA 80 >UniRef50_A1CTI6 Cluster: SIR2 family histone deacetylase, putative; n=8; Eurotiomycetidae|Rep: SIR2 family histone deacetylase, putative - Aspergillus clavatus Length = 320 Score = 39.5 bits (88), Expect = 0.078 Identities = 15/33 (45%), Positives = 22/33 (66%) Frame = +2 Query: 350 QLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 + +K K I+ GAG+S S+G+P FRG G+W Sbjct: 16 EYLKGCKRIIALCGAGLSASSGLPTFRGAGGLW 48 >UniRef50_O59923 Cluster: NAD-dependent histone deacetylase SIR2; n=3; Candida albicans|Rep: NAD-dependent histone deacetylase SIR2 - Candida albicans (Yeast) Length = 515 Score = 39.5 bits (88), Expect = 0.078 Identities = 21/38 (55%), Positives = 26/38 (68%), Gaps = 3/38 (7%) Frame = +2 Query: 344 LAQLVKD---SKHIVVHTGAGISTSAGIPDFRGPNGVW 448 L L+ D +K I+V TGAGISTS GIPDFR G++ Sbjct: 224 LPDLISDLSRAKKIMVVTGAGISTSLGIPDFRSFKGLY 261 >UniRef50_Q8U1Q1 Cluster: NAD-dependent deacetylase; n=19; cellular organisms|Rep: NAD-dependent deacetylase - Pyrococcus furiosus Length = 250 Score = 39.5 bits (88), Expect = 0.078 Identities = 15/35 (42%), Positives = 24/35 (68%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 +++++ S + TGAGIS +GIP FRG +G+W Sbjct: 5 VSKILAKSSMAIAFTGAGISAESGIPTFRGKDGLW 39 >UniRef50_UPI0000519F58 Cluster: PREDICTED: similar to Sirt4 CG3187-PC, isoform C isoform 2; n=2; Endopterygota|Rep: PREDICTED: similar to Sirt4 CG3187-PC, isoform C isoform 2 - Apis mellifera Length = 302 Score = 39.1 bits (87), Expect = 0.10 Identities = 20/53 (37%), Positives = 28/53 (52%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFADA 502 L + +I V TGAGIST +GIPD+R GV + KP + F ++ Sbjct: 33 LKDFIDSHDNICVLTGAGISTESGIPDYRS-EGVGLYARSNHKPVLYKDFCNS 84 >UniRef50_UPI00004997CB Cluster: Sir2 family transcriptional regulator; n=2; Entamoeba histolytica HM-1:IMSS|Rep: Sir2 family transcriptional regulator - Entamoeba histolytica HM-1:IMSS Length = 346 Score = 39.1 bits (87), Expect = 0.10 Identities = 20/37 (54%), Positives = 23/37 (62%) Frame = +2 Query: 326 NQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGP 436 N K L + ++VV GAGISTSAGIPDFR P Sbjct: 89 NAKGFGLFMKYRKPSNVVVMAGAGISTSAGIPDFRTP 125 >UniRef50_A4A980 Cluster: NAD-dependent deacetylase; n=5; Gammaproteobacteria|Rep: NAD-dependent deacetylase - Congregibacter litoralis KT71 Length = 241 Score = 39.1 bits (87), Expect = 0.10 Identities = 15/30 (50%), Positives = 19/30 (63%) Frame = +2 Query: 386 TGAGISTSAGIPDFRGPNGVWTLEKEGKKP 475 TGAG+S +GIP FRG +G WT+ P Sbjct: 7 TGAGVSAESGIPTFRGEDGFWTIGSRNYTP 36 >UniRef50_A1I9S7 Cluster: NAD-dependent deacetylase; n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: NAD-dependent deacetylase - Candidatus Desulfococcus oleovorans Hxd3 Length = 273 Score = 39.1 bits (87), Expect = 0.10 Identities = 15/34 (44%), Positives = 22/34 (64%) Frame = +2 Query: 347 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 A+++ + V +GAG+S +GIP FR P GVW Sbjct: 11 AKVLAGASRAAVFSGAGVSAESGIPTFRDPGGVW 44 >UniRef50_A1FG80 Cluster: Silent information regulator protein Sir2; n=3; Pseudomonas|Rep: Silent information regulator protein Sir2 - Pseudomonas putida W619 Length = 252 Score = 39.1 bits (87), Expect = 0.10 Identities = 16/35 (45%), Positives = 25/35 (71%), Gaps = 1/35 (2%) Frame = +2 Query: 347 AQLVKDSKHIVVHTGAGISTSAGIPDFRGP-NGVW 448 A+ ++ ++HI+V TGAG+S +GIP FR G+W Sbjct: 8 AEALRSAQHIMVFTGAGVSAGSGIPTFRDELTGLW 42 >UniRef50_Q54P49 Cluster: Zn finger-containing protein; n=1; Dictyostelium discoideum AX4|Rep: Zn finger-containing protein - Dictyostelium discoideum AX4 Length = 456 Score = 39.1 bits (87), Expect = 0.10 Identities = 25/70 (35%), Positives = 40/70 (57%), Gaps = 4/70 (5%) Frame = +2 Query: 272 ENKGILGVPEKFDSNDKL-NQKCVLLAQLVKDSK--HIVVHTGAGISTSAGIPDFRG-PN 439 +N I+ K ++ ++ N K +L+K+ K +I+V TGAGIS ++GIPDFR Sbjct: 146 KNSNIIKNEIKIENEIEIENNKIKEFIKLIKNDKCKNIIVLTGAGISVASGIPDFRSVET 205 Query: 440 GVWTLEKEGK 469 G++ E K Sbjct: 206 GLYNNENVSK 215 >UniRef50_Q298C7 Cluster: GA18650-PA; n=1; Drosophila pseudoobscura|Rep: GA18650-PA - Drosophila pseudoobscura (Fruit fly) Length = 381 Score = 39.1 bits (87), Expect = 0.10 Identities = 17/23 (73%), Positives = 18/23 (78%) Frame = +2 Query: 368 KHIVVHTGAGISTSAGIPDFRGP 436 K I+ GAGISTSAGIPDFR P Sbjct: 76 KKIITMVGAGISTSAGIPDFRSP 98 >UniRef50_Q5KDE0 Cluster: NAD-dependent histone deacetylase, putative; n=2; Filobasidiella neoformans|Rep: NAD-dependent histone deacetylase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 413 Score = 39.1 bits (87), Expect = 0.10 Identities = 23/52 (44%), Positives = 31/52 (59%), Gaps = 2/52 (3%) Frame = +2 Query: 290 GVPEKFDSNDKLNQKCVLLAQLVK--DSKHIVVHTGAGISTSAGIPDFRGPN 439 G+ + S D LN A +K ++K ++ GAGISTSAGIPDFR P+ Sbjct: 46 GIDDGALSGDDLNP-LRKAASFIKSGNAKDVIFLLGAGISTSAGIPDFRSPS 96 >UniRef50_P06700 Cluster: NAD-dependent histone deacetylase SIR2; n=13; Saccharomycetales|Rep: NAD-dependent histone deacetylase SIR2 - Saccharomyces cerevisiae (Baker's yeast) Length = 562 Score = 39.1 bits (87), Expect = 0.10 Identities = 17/34 (50%), Positives = 24/34 (70%) Frame = +2 Query: 350 QLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 451 Q + ++ I+V TGAG+STS GIPDFR G ++ Sbjct: 249 QKLHTARKILVLTGAGVSTSLGIPDFRSSEGFYS 282 >UniRef50_Q885X7 Cluster: NAD-dependent deacetylase 2; n=4; Pseudomonas|Rep: NAD-dependent deacetylase 2 - Pseudomonas syringae pv. tomato Length = 248 Score = 39.1 bits (87), Expect = 0.10 Identities = 17/43 (39%), Positives = 27/43 (62%) Frame = +2 Query: 347 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKP 475 A ++ +K I+V TGAG+S +G+P +RG G++ E E P Sbjct: 5 ASALRHAKRILVITGAGLSADSGLPTYRGVGGLYNGETEDGLP 47 >UniRef50_UPI000050FCF4 Cluster: COG0846: NAD-dependent protein deacetylases, SIR2 family; n=1; Brevibacterium linens BL2|Rep: COG0846: NAD-dependent protein deacetylases, SIR2 family - Brevibacterium linens BL2 Length = 309 Score = 38.7 bits (86), Expect = 0.14 Identities = 21/51 (41%), Positives = 30/51 (58%), Gaps = 1/51 (1%) Frame = +2 Query: 296 PEKFDSNDKLNQKCVLLAQLVK-DSKHIVVHTGAGISTSAGIPDFRGPNGV 445 PE S+D++ A V D+ V TGAG+ST +G+PD+RGP+ V Sbjct: 14 PEPSHSDDEIIDVLTGTAGAVGIDTSGWAVLTGAGMSTDSGVPDYRGPDAV 64 >UniRef50_Q4S7H2 Cluster: Chromosome 13 SCAF14715, whole genome shotgun sequence; n=6; Clupeocephala|Rep: Chromosome 13 SCAF14715, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 327 Score = 38.7 bits (86), Expect = 0.14 Identities = 22/47 (46%), Positives = 33/47 (70%), Gaps = 3/47 (6%) Frame = +2 Query: 344 LAQLVK--DSKHIVVHTGAGISTSAGIPDFRGP-NGVWTLEKEGKKP 475 +A+LVK +++VV GAGIST++GIPDFR P G++ ++ K P Sbjct: 39 VARLVKLGRCRNVVVVAGAGISTASGIPDFRTPGTGLYANLEQYKLP 85 >UniRef50_Q03ZB1 Cluster: NAD-dependent protein deacetylase, SIR2 family; n=3; Leuconostocaceae|Rep: NAD-dependent protein deacetylase, SIR2 family - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 234 Score = 38.7 bits (86), Expect = 0.14 Identities = 15/29 (51%), Positives = 23/29 (79%) Frame = +2 Query: 362 DSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 ++K+IV TGAG+ST +GIPD+R G++ Sbjct: 13 NAKNIVFMTGAGVSTLSGIPDYRSKGGIY 41 >UniRef50_Q8SSB6 Cluster: SIR2-LIKE PROTEIN INVOLVED IN TELOMERIC SILENCING; n=1; Encephalitozoon cuniculi|Rep: SIR2-LIKE PROTEIN INVOLVED IN TELOMERIC SILENCING - Encephalitozoon cuniculi Length = 425 Score = 38.7 bits (86), Expect = 0.14 Identities = 16/27 (59%), Positives = 22/27 (81%) Frame = +2 Query: 368 KHIVVHTGAGISTSAGIPDFRGPNGVW 448 + +VV TGAGIS S+GIPDFR +G++ Sbjct: 86 RRVVVITGAGISVSSGIPDFRSKSGLF 112 >UniRef50_Q750H1 Cluster: AGL018Cp; n=1; Eremothecium gossypii|Rep: AGL018Cp - Ashbya gossypii (Yeast) (Eremothecium gossypii) Length = 340 Score = 38.7 bits (86), Expect = 0.14 Identities = 21/42 (50%), Positives = 25/42 (59%), Gaps = 1/42 (2%) Frame = +2 Query: 374 IVVHTGAGISTSAGIPDFRGPN-GVWTLEKEGKKPTINVSFA 496 +V GAGISTS GIPDFR PN G++ + K P FA Sbjct: 24 VVFLVGAGISTSCGIPDFRSPNTGLYHNLSKFKLPYAEAVFA 65 >UniRef50_A5DJ74 Cluster: Putative uncharacterized protein; n=1; Pichia guilliermondii|Rep: Putative uncharacterized protein - Pichia guilliermondii (Yeast) (Candida guilliermondii) Length = 522 Score = 38.7 bits (86), Expect = 0.14 Identities = 17/31 (54%), Positives = 23/31 (74%) Frame = +2 Query: 356 VKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 ++ +K I+V +GAGISTS GIPDFR G + Sbjct: 206 LQSAKKILVLSGAGISTSLGIPDFRSSQGFY 236 >UniRef50_A4RCT8 Cluster: Putative uncharacterized protein; n=3; Magnaporthe grisea|Rep: Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 1040 Score = 38.7 bits (86), Expect = 0.14 Identities = 15/28 (53%), Positives = 21/28 (75%) Frame = +2 Query: 365 SKHIVVHTGAGISTSAGIPDFRGPNGVW 448 S++IV GAG+S S+G+ FRGP G+W Sbjct: 33 SRNIVAIIGAGLSASSGLATFRGPGGLW 60 >UniRef50_Q8R216 Cluster: NAD-dependent deacetylase sirtuin-4; n=7; cellular organisms|Rep: NAD-dependent deacetylase sirtuin-4 - Mus musculus (Mouse) Length = 333 Score = 38.7 bits (86), Expect = 0.14 Identities = 20/60 (33%), Positives = 33/60 (55%) Frame = +2 Query: 329 QKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFADAQP 508 +K L + + SK ++V TGAGIST + IPD+R V + ++P ++ F + P Sbjct: 39 EKIKELQRFISLSKKLLVMTGAGISTESSIPDYRSEK-VGLYARTDRRPIQHIDFVRSAP 97 >UniRef50_Q9Y6E7 Cluster: NAD-dependent deacetylase sirtuin-4; n=23; Deuterostomia|Rep: NAD-dependent deacetylase sirtuin-4 - Homo sapiens (Human) Length = 314 Score = 38.7 bits (86), Expect = 0.14 Identities = 21/60 (35%), Positives = 33/60 (55%) Frame = +2 Query: 329 QKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFADAQP 508 +K L + + SK ++V TGAGIST +GIPD+R V + ++P + F + P Sbjct: 42 EKVKELQRFITLSKRLLVMTGAGISTESGIPDYRSEK-VGLYARTDRRPIQHGDFVRSAP 100 >UniRef50_A7HID4 Cluster: Silent information regulator protein Sir2; n=9; Deltaproteobacteria|Rep: Silent information regulator protein Sir2 - Anaeromyxobacter sp. Fw109-5 Length = 289 Score = 38.3 bits (85), Expect = 0.18 Identities = 18/52 (34%), Positives = 29/52 (55%) Frame = +2 Query: 347 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFADA 502 A ++ + +VV GAG+ +G+PDFRG G W ++ + +SF DA Sbjct: 9 AAALRSAGALVVTAGAGMGVDSGLPDFRGDQGFWKAYPPYER--LGLSFVDA 58 >UniRef50_A7H7B6 Cluster: Silent information regulator protein Sir2; n=2; Anaeromyxobacter|Rep: Silent information regulator protein Sir2 - Anaeromyxobacter sp. Fw109-5 Length = 270 Score = 38.3 bits (85), Expect = 0.18 Identities = 17/45 (37%), Positives = 23/45 (51%) Frame = +2 Query: 341 LLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKP 475 LL + + +V TGAG+S +GIP FRG G W + P Sbjct: 8 LLDDVRRAQGRVVALTGAGVSAESGIPTFRGREGFWVVGSRNYMP 52 >UniRef50_A0PU12 Cluster: Sir2-like regulatory protein; n=1; Mycobacterium ulcerans Agy99|Rep: Sir2-like regulatory protein - Mycobacterium ulcerans (strain Agy99) Length = 283 Score = 38.3 bits (85), Expect = 0.18 Identities = 16/22 (72%), Positives = 19/22 (86%) Frame = +2 Query: 374 IVVHTGAGISTSAGIPDFRGPN 439 I V TGAGIST +GIPD+RGP+ Sbjct: 15 IAVLTGAGISTDSGIPDYRGPD 36 >UniRef50_Q8IRR5 Cluster: CG3187-PC, isoform C; n=4; Diptera|Rep: CG3187-PC, isoform C - Drosophila melanogaster (Fruit fly) Length = 312 Score = 38.3 bits (85), Expect = 0.18 Identities = 19/50 (38%), Positives = 28/50 (56%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSF 493 L + +++V TGAGIST +GIPD+R GV + KP ++ F Sbjct: 38 LEDFLLSKPNVLVLTGAGISTESGIPDYRS-EGVGLYARSNHKPVQHMEF 86 >UniRef50_A2DKF0 Cluster: Transcriptional regulator, Sir2 family protein; n=1; Trichomonas vaginalis G3|Rep: Transcriptional regulator, Sir2 family protein - Trichomonas vaginalis G3 Length = 347 Score = 38.3 bits (85), Expect = 0.18 Identities = 19/42 (45%), Positives = 29/42 (69%), Gaps = 1/42 (2%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW-TLEKEG 466 + +L+++SKHI+V GAG S PDFR P G++ ++ KEG Sbjct: 61 IIKLIENSKHIIVIIGAGASIG---PDFRSPGGLYDSIAKEG 99 >UniRef50_Q6CAJ8 Cluster: Similar to sp|P53687 Saccharomyces cerevisiae HST3 protein; n=1; Yarrowia lipolytica|Rep: Similar to sp|P53687 Saccharomyces cerevisiae HST3 protein - Yarrowia lipolytica (Candida lipolytica) Length = 385 Score = 38.3 bits (85), Expect = 0.18 Identities = 18/29 (62%), Positives = 21/29 (72%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFR 430 L Q++ K +V TGAGIS SAGIPDFR Sbjct: 17 LQQILGKCKRVVCVTGAGISCSAGIPDFR 45 >UniRef50_A4QX96 Cluster: Putative uncharacterized protein; n=2; Magnaporthe grisea|Rep: Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 534 Score = 38.3 bits (85), Expect = 0.18 Identities = 16/21 (76%), Positives = 18/21 (85%) Frame = +2 Query: 374 IVVHTGAGISTSAGIPDFRGP 436 I++ GAGISTSAGIPDFR P Sbjct: 38 IIILAGAGISTSAGIPDFRSP 58 >UniRef50_A3LN35 Cluster: NAD-dependent histone deacetylase SIR2; n=1; Pichia stipitis|Rep: NAD-dependent histone deacetylase SIR2 - Pichia stipitis (Yeast) Length = 391 Score = 38.3 bits (85), Expect = 0.18 Identities = 20/36 (55%), Positives = 26/36 (72%) Frame = +2 Query: 341 LLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 LL+ L +K I+V +GAGISTS GIPDFR G++ Sbjct: 103 LLSDLTS-AKKIMVISGAGISTSLGIPDFRSFKGLY 137 >UniRef50_A2QWZ2 Cluster: Function: human SIRT5 belongs to the Sir2-like proteins precursor; n=1; Aspergillus niger|Rep: Function: human SIRT5 belongs to the Sir2-like proteins precursor - Aspergillus niger Length = 258 Score = 38.3 bits (85), Expect = 0.18 Identities = 14/31 (45%), Positives = 21/31 (67%) Frame = +2 Query: 356 VKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 +K + ++ GAGIS S+G+P FRG G+W Sbjct: 18 LKGCRRVIALLGAGISASSGLPTFRGAGGLW 48 >UniRef50_Q7WLE5 Cluster: NAD-dependent deacetylase; n=47; Bacteria|Rep: NAD-dependent deacetylase - Bordetella bronchiseptica (Alcaligenes bronchisepticus) Length = 274 Score = 38.3 bits (85), Expect = 0.18 Identities = 21/51 (41%), Positives = 30/51 (58%), Gaps = 1/51 (1%) Frame = +2 Query: 365 SKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINV-SFADAQPQK 514 S+ + V TGAG ST++GIPD+R G W +KP I+ +F QP + Sbjct: 18 SERLFVLTGAGCSTASGIPDYRDGQGQWK-----RKPPIDFQAFMGGQPAR 63 >UniRef50_UPI00015B4FA0 Cluster: PREDICTED: similar to chromatin regulatory protein sir2; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to chromatin regulatory protein sir2 - Nasonia vitripennis Length = 736 Score = 37.9 bits (84), Expect = 0.24 Identities = 23/53 (43%), Positives = 29/53 (54%) Frame = +2 Query: 341 LLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFAD 499 +L V S I V TGAGIST +GIPD+R GV ++P VS+ D Sbjct: 466 MLKHFVNTSGKICVITGAGISTESGIPDYRS-EGVGLFATSDRRP---VSYQD 514 >UniRef50_UPI00006CA40C Cluster: transcriptional regulator, Sir2 family protein; n=1; Tetrahymena thermophila SB210|Rep: transcriptional regulator, Sir2 family protein - Tetrahymena thermophila SB210 Length = 471 Score = 37.9 bits (84), Expect = 0.24 Identities = 20/35 (57%), Positives = 26/35 (74%), Gaps = 1/35 (2%) Frame = +2 Query: 374 IVVHTGAGISTSAGIPDFRGP-NGVWTLEKEGKKP 475 IV TGAGIS SAGIPDFR P +G+++ ++ K P Sbjct: 214 IVFLTGAGISVSAGIPDFRTPGSGLYSQLQKYKLP 248 >UniRef50_Q4QKL5 Cluster: NAD-dependent deacetylase sirtuin 5; n=11; Haemophilus influenzae|Rep: NAD-dependent deacetylase sirtuin 5 - Haemophilus influenzae (strain 86-028NP) Length = 281 Score = 37.9 bits (84), Expect = 0.24 Identities = 17/50 (34%), Positives = 29/50 (58%) Frame = +2 Query: 350 QLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFAD 499 +L++ + I++ GAG+S +G+PDFR G W K+ N+SF + Sbjct: 10 ELIRKADGILITAGAGMSVDSGLPDFRSVGGFWNAYPMFKEH--NISFEE 57 >UniRef50_Q1D737 Cluster: NAD-dependent deacetylase; n=1; Myxococcus xanthus DK 1622|Rep: NAD-dependent deacetylase - Myxococcus xanthus (strain DK 1622) Length = 245 Score = 37.9 bits (84), Expect = 0.24 Identities = 16/33 (48%), Positives = 24/33 (72%), Gaps = 1/33 (3%) Frame = +2 Query: 353 LVKDSKH-IVVHTGAGISTSAGIPDFRGPNGVW 448 L+ DS ++V TGAG+S +G+P FRG +G+W Sbjct: 4 LILDSNTWLLVLTGAGVSAESGVPTFRGMSGLW 36 >UniRef50_A6XDL2 Cluster: Sirtuin 1; n=2; Schistosoma|Rep: Sirtuin 1 - Schistosoma mansoni (Blood fluke) Length = 568 Score = 37.9 bits (84), Expect = 0.24 Identities = 17/32 (53%), Positives = 22/32 (68%) Frame = +2 Query: 353 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 L+ I+V TGAGIS S GIPDFR +G++ Sbjct: 150 LLSTCTSILVITGAGISVSCGIPDFRSRDGIY 181 >UniRef50_Q8IXJ6 Cluster: NAD-dependent deacetylase sirtuin-2; n=31; Coelomata|Rep: NAD-dependent deacetylase sirtuin-2 - Homo sapiens (Human) Length = 389 Score = 37.9 bits (84), Expect = 0.24 Identities = 19/33 (57%), Positives = 25/33 (75%), Gaps = 2/33 (6%) Frame = +2 Query: 368 KHIVVHTGAGISTSAGIPDFRGPN-GVW-TLEK 460 + ++ GAGISTSAGIPDFR P+ G++ LEK Sbjct: 77 RRVICLVGAGISTSAGIPDFRSPSTGLYDNLEK 109 >UniRef50_Q6C8C7 Cluster: Similar to DEHA0C01507g Debaryomyces hansenii IPF 2468.1; n=2; Ascomycota|Rep: Similar to DEHA0C01507g Debaryomyces hansenii IPF 2468.1 - Yarrowia lipolytica (Candida lipolytica) Length = 303 Score = 37.5 bits (83), Expect = 0.31 Identities = 14/28 (50%), Positives = 20/28 (71%) Frame = +2 Query: 365 SKHIVVHTGAGISTSAGIPDFRGPNGVW 448 S+ I+ GAG+S S+G+P FRG G+W Sbjct: 16 SRKILALVGAGLSQSSGLPTFRGEGGIW 43 >UniRef50_A6SP88 Cluster: Putative uncharacterized protein; n=2; Sclerotiniaceae|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 332 Score = 37.5 bits (83), Expect = 0.31 Identities = 20/51 (39%), Positives = 28/51 (54%) Frame = +2 Query: 296 PEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 PE SND + K VL + S ++ GAG+ S+G+ FRGP G+W Sbjct: 17 PEHRPSNDVASFKKVLAS-----STRVLALCGAGLGASSGLDTFRGPGGMW 62 >UniRef50_Q9NTG7 Cluster: NAD-dependent deacetylase sirtuin-3, mitochondrial precursor; n=22; Euteleostomi|Rep: NAD-dependent deacetylase sirtuin-3, mitochondrial precursor - Homo sapiens (Human) Length = 399 Score = 37.5 bits (83), Expect = 0.31 Identities = 20/44 (45%), Positives = 28/44 (63%), Gaps = 2/44 (4%) Frame = +2 Query: 311 SNDKLNQKCVLLAQLVKDS--KHIVVHTGAGISTSAGIPDFRGP 436 S+DK +A+L++ + +VV GAGIST +GIPDFR P Sbjct: 117 SSDKGKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSP 160 >UniRef50_UPI0000499DEA Cluster: Sir2 family transcriptional regulator; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Sir2 family transcriptional regulator - Entamoeba histolytica HM-1:IMSS Length = 383 Score = 37.1 bits (82), Expect = 0.41 Identities = 15/23 (65%), Positives = 19/23 (82%) Frame = +2 Query: 368 KHIVVHTGAGISTSAGIPDFRGP 436 K+I+ GAG+ST+AGIPDFR P Sbjct: 135 KNIIALVGAGMSTTAGIPDFRSP 157 >UniRef50_A2ABY8 Cluster: Sirtuin 7 (Silent mating type information regulation 2, homolog) 7; n=2; Murinae|Rep: Sirtuin 7 (Silent mating type information regulation 2, homolog) 7 - Mus musculus (Mouse) Length = 121 Score = 37.1 bits (82), Expect = 0.41 Identities = 19/43 (44%), Positives = 27/43 (62%) Frame = +2 Query: 299 EKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDF 427 E D ++L +K LA V+ ++H+VV+TGAGIST I F Sbjct: 78 EVCDDPEELRRKVRELAGAVRSARHLVVYTGAGISTCRQIDRF 120 >UniRef50_Q1RL71 Cluster: Zinc finger protein; n=2; Ciona intestinalis|Rep: Zinc finger protein - Ciona intestinalis (Transparent sea squirt) Length = 523 Score = 37.1 bits (82), Expect = 0.41 Identities = 17/33 (51%), Positives = 24/33 (72%), Gaps = 2/33 (6%) Frame = +2 Query: 344 LAQLVKDS--KHIVVHTGAGISTSAGIPDFRGP 436 +A+L+ ++I+V GAGIST +GIPDFR P Sbjct: 110 VAELISSGGVRNIIVMAGAGISTGSGIPDFRTP 142 >UniRef50_Q882K4 Cluster: NAD-dependent deacetylase 3; n=5; Pseudomonas|Rep: NAD-dependent deacetylase 3 - Pseudomonas syringae pv. tomato Length = 281 Score = 37.1 bits (82), Expect = 0.41 Identities = 16/26 (61%), Positives = 21/26 (80%) Frame = +2 Query: 368 KHIVVHTGAGISTSAGIPDFRGPNGV 445 K +V TGAGIST++GIPD+R +GV Sbjct: 20 KSFLVVTGAGISTASGIPDYRDKDGV 45 >UniRef50_Q7PS76 Cluster: ENSANGP00000025231; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000025231 - Anopheles gambiae str. PEST Length = 182 Score = 36.7 bits (81), Expect = 0.55 Identities = 19/44 (43%), Positives = 26/44 (59%) Frame = +2 Query: 374 IVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFADAQ 505 I+V TGAGIST +GIPD+R GV + KP + F ++ Sbjct: 1 ILVLTGAGISTESGIPDYRS-EGVGLYARSNHKPIQHGDFVKSE 43 >UniRef50_A2F9H1 Cluster: Transcriptional regulator, Sir2 family protein; n=2; Trichomonas vaginalis|Rep: Transcriptional regulator, Sir2 family protein - Trichomonas vaginalis G3 Length = 304 Score = 36.7 bits (81), Expect = 0.55 Identities = 16/22 (72%), Positives = 19/22 (86%) Frame = +2 Query: 365 SKHIVVHTGAGISTSAGIPDFR 430 +K I+ TGAGIST+AGIPDFR Sbjct: 24 AKKIIFLTGAGISTAAGIPDFR 45 >UniRef50_Q89EA6 Cluster: NAD-dependent deacetylase 2; n=9; Proteobacteria|Rep: NAD-dependent deacetylase 2 - Bradyrhizobium japonicum Length = 273 Score = 36.7 bits (81), Expect = 0.55 Identities = 16/35 (45%), Positives = 22/35 (62%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 L V + + V TGAG ST++GIPD+R +G W Sbjct: 11 LQDFVARHQRLFVLTGAGCSTNSGIPDYRDSHGNW 45 >UniRef50_Q07FY7 Cluster: Sirtuin (Silent mating type information regulation 2 homolog) 3; n=3; Xenopus|Rep: Sirtuin (Silent mating type information regulation 2 homolog) 3 - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 401 Score = 36.3 bits (80), Expect = 0.72 Identities = 15/22 (68%), Positives = 19/22 (86%) Frame = +2 Query: 371 HIVVHTGAGISTSAGIPDFRGP 436 +I+V GAGIST++GIPDFR P Sbjct: 128 NIIVMAGAGISTASGIPDFRTP 149 >UniRef50_Q62HT8 Cluster: Transcriptional regulator, Sir2 family; n=39; Bacteria|Rep: Transcriptional regulator, Sir2 family - Burkholderia mallei (Pseudomonas mallei) Length = 450 Score = 36.3 bits (80), Expect = 0.72 Identities = 13/25 (52%), Positives = 18/25 (72%) Frame = +2 Query: 374 IVVHTGAGISTSAGIPDFRGPNGVW 448 ++V GAGI +G+PDFRG G+W Sbjct: 196 LLVTAGAGIGIDSGLPDFRGAEGLW 220 >UniRef50_A4A8B4 Cluster: Silent information regulator protein Sir2; n=1; Congregibacter litoralis KT71|Rep: Silent information regulator protein Sir2 - Congregibacter litoralis KT71 Length = 297 Score = 36.3 bits (80), Expect = 0.72 Identities = 18/42 (42%), Positives = 25/42 (59%) Frame = +2 Query: 323 LNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 L+ + L+ L+ D ++V TGAGIS S GIP +R G W Sbjct: 7 LHAESDFLSALI-DHAPVLVITGAGISVSTGIPTYRDEKGAW 47 >UniRef50_A1ZZG3 Cluster: NAD-dependent deacetylase; n=35; Bacteria|Rep: NAD-dependent deacetylase - Microscilla marina ATCC 23134 Length = 245 Score = 36.3 bits (80), Expect = 0.72 Identities = 17/42 (40%), Positives = 26/42 (61%) Frame = +2 Query: 323 LNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 L+ K +++ + + IVV TGAGIS +GI FR +G+W Sbjct: 2 LSFKSQQVSKSIMSKQKIVVLTGAGISAESGISTFRDSDGLW 43 >UniRef50_A7SK95 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 323 Score = 36.3 bits (80), Expect = 0.72 Identities = 19/46 (41%), Positives = 27/46 (58%) Frame = +2 Query: 293 VPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFR 430 VPE S +L+ L + + ++ I V TGAGIST +GI D+R Sbjct: 36 VPEFHTSKQELSYITSRLDEFIAENPKIFVITGAGISTESGIRDYR 81 >UniRef50_Q6FKU1 Cluster: Similar to sp|P53686 Saccharomyces cerevisiae YPL015c; n=3; Saccharomycetales|Rep: Similar to sp|P53686 Saccharomyces cerevisiae YPL015c - Candida glabrata (Yeast) (Torulopsis glabrata) Length = 364 Score = 36.3 bits (80), Expect = 0.72 Identities = 15/24 (62%), Positives = 18/24 (75%) Frame = +2 Query: 365 SKHIVVHTGAGISTSAGIPDFRGP 436 S ++ GAGISTS+GIPDFR P Sbjct: 16 SSKVIFLVGAGISTSSGIPDFRSP 39 >UniRef50_Q88BY5 Cluster: NAD-dependent deacetylase; n=9; Bacteria|Rep: NAD-dependent deacetylase - Pseudomonas putida (strain KT2440) Length = 262 Score = 36.3 bits (80), Expect = 0.72 Identities = 17/35 (48%), Positives = 23/35 (65%), Gaps = 1/35 (2%) Frame = +2 Query: 347 AQLVKDSKHIVVHTGAGISTSAGIPDFRGP-NGVW 448 A+ ++ SK +V TGAGIS +GIP FR G+W Sbjct: 8 AEALRRSKTVVFFTGAGISADSGIPTFRDKLTGLW 42 >UniRef50_Q9I4E1 Cluster: NAD-dependent deacetylase 2; n=6; Pseudomonadaceae|Rep: NAD-dependent deacetylase 2 - Pseudomonas aeruginosa Length = 256 Score = 36.3 bits (80), Expect = 0.72 Identities = 16/44 (36%), Positives = 28/44 (63%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKP 475 +AQ ++ ++ I+V TGAG+S +G+P +RG G++ E P Sbjct: 10 VAQALRRAERILVITGAGLSADSGMPTYRGLGGLYNGRTEEGLP 53 >UniRef50_Q1D9X2 Cluster: Sir2 family protein; n=1; Myxococcus xanthus DK 1622|Rep: Sir2 family protein - Myxococcus xanthus (strain DK 1622) Length = 287 Score = 35.9 bits (79), Expect = 0.96 Identities = 15/20 (75%), Positives = 17/20 (85%) Frame = +2 Query: 377 VVHTGAGISTSAGIPDFRGP 436 VV TGAG ST +GIPD+RGP Sbjct: 30 VVLTGAGCSTESGIPDYRGP 49 >UniRef50_Q6MJJ2 Cluster: NAD-dependent deacetylase; n=5; Proteobacteria|Rep: NAD-dependent deacetylase - Bdellovibrio bacteriovorus Length = 235 Score = 35.9 bits (79), Expect = 0.96 Identities = 15/27 (55%), Positives = 20/27 (74%) Frame = +2 Query: 368 KHIVVHTGAGISTSAGIPDFRGPNGVW 448 K+IV+ TGAGIS +GI FR +G+W Sbjct: 7 KNIVILTGAGISAESGIRTFRDQDGLW 33 >UniRef50_Q8FUC8 Cluster: NAD-dependent deacetylase 1; n=6; Corynebacterium|Rep: NAD-dependent deacetylase 1 - Corynebacterium efficiens Length = 281 Score = 35.9 bits (79), Expect = 0.96 Identities = 13/23 (56%), Positives = 18/23 (78%) Frame = +2 Query: 374 IVVHTGAGISTSAGIPDFRGPNG 442 ++ TGAG+ST +GIPD+R P G Sbjct: 19 VLAVTGAGVSTDSGIPDYRSPRG 41 >UniRef50_UPI00005A356B Cluster: PREDICTED: similar to NAD-dependent deacetylase sirtuin-3, mitochondrial precursor (SIR2-like protein 3) (hSIRT3) isoform 1; n=2; Canis lupus familiaris|Rep: PREDICTED: similar to NAD-dependent deacetylase sirtuin-3, mitochondrial precursor (SIR2-like protein 3) (hSIRT3) isoform 1 - Canis familiaris Length = 248 Score = 35.5 bits (78), Expect = 1.3 Identities = 16/33 (48%), Positives = 24/33 (72%), Gaps = 2/33 (6%) Frame = +2 Query: 344 LAQLVKDS--KHIVVHTGAGISTSAGIPDFRGP 436 +A+L++ + ++V GAGIST +GIPDFR P Sbjct: 101 IAELIRARACQRVLVMVGAGISTPSGIPDFRSP 133 >UniRef50_Q1QTH0 Cluster: Silent information regulator protein Sir2; n=2; Oceanospirillales|Rep: Silent information regulator protein Sir2 - Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB13768) Length = 242 Score = 35.5 bits (78), Expect = 1.3 Identities = 14/26 (53%), Positives = 19/26 (73%) Frame = +2 Query: 371 HIVVHTGAGISTSAGIPDFRGPNGVW 448 H+VV TGAGIS +G+ FR +G+W Sbjct: 8 HLVVLTGAGISAESGLKTFRDGDGLW 33 >UniRef50_A0JXS0 Cluster: Silent information regulator protein Sir2 precursor; n=11; Actinomycetales|Rep: Silent information regulator protein Sir2 precursor - Arthrobacter sp. (strain FB24) Length = 306 Score = 35.5 bits (78), Expect = 1.3 Identities = 13/18 (72%), Positives = 17/18 (94%) Frame = +2 Query: 386 TGAGISTSAGIPDFRGPN 439 TGAG+ST +GIPD+RGP+ Sbjct: 48 TGAGLSTDSGIPDYRGPD 65 >UniRef50_Q4DP02 Cluster: Silent information regulator 2, putative; n=4; Trypanosoma|Rep: Silent information regulator 2, putative - Trypanosoma cruzi Length = 359 Score = 35.5 bits (78), Expect = 1.3 Identities = 15/22 (68%), Positives = 18/22 (81%) Frame = +2 Query: 374 IVVHTGAGISTSAGIPDFRGPN 439 I+V GAGIS +AGIPDFR P+ Sbjct: 32 ILVMAGAGISVAAGIPDFRSPH 53 >UniRef50_A2F8N6 Cluster: Transcriptional regulator, Sir2 family protein; n=1; Trichomonas vaginalis G3|Rep: Transcriptional regulator, Sir2 family protein - Trichomonas vaginalis G3 Length = 320 Score = 35.5 bits (78), Expect = 1.3 Identities = 16/39 (41%), Positives = 27/39 (69%), Gaps = 1/39 (2%) Frame = +2 Query: 362 DSKHIVVHTGAGISTSAGIPDFRGPN-GVWTLEKEGKKP 475 ++K I++ +GAG S ++GIPDFR P G+++ K+ P Sbjct: 35 NAKKILIFSGAGTSVASGIPDFRSPKIGLYSQLKKYNLP 73 >UniRef50_P48324 Cluster: Uncharacterized 24.3 kDa protein in psbH-rpl11 intergenic region; n=1; Cyanophora paradoxa|Rep: Uncharacterized 24.3 kDa protein in psbH-rpl11 intergenic region - Cyanophora paradoxa Length = 182 Score = 35.5 bits (78), Expect = 1.3 Identities = 18/52 (34%), Positives = 33/52 (63%) Frame = -3 Query: 305 ISLGLLVYLCFHKVIVLCIIARHFWETIYLMVLTQIFIEPLFKFKLRIFFYN 150 ISL L+Y + + ++ I HF YL+VL ++ ++P+F++ + IFF+N Sbjct: 101 ISLVNLLYKAIYWIYIIFAIFLHFMN--YLLVLLELTLQPIFEW-IEIFFFN 149 >UniRef50_Q9RL35 Cluster: NAD-dependent deacetylase 1; n=8; Actinomycetales|Rep: NAD-dependent deacetylase 1 - Streptomyces coelicolor Length = 299 Score = 35.5 bits (78), Expect = 1.3 Identities = 14/23 (60%), Positives = 19/23 (82%) Frame = +2 Query: 374 IVVHTGAGISTSAGIPDFRGPNG 442 ++V +GAGIST +GIPD+RG G Sbjct: 34 VLVLSGAGISTESGIPDYRGEGG 56 >UniRef50_Q9I4L0 Cluster: NAD-dependent deacetylase 1; n=10; Bacteria|Rep: NAD-dependent deacetylase 1 - Pseudomonas aeruginosa Length = 250 Score = 35.5 bits (78), Expect = 1.3 Identities = 14/36 (38%), Positives = 24/36 (66%), Gaps = 1/36 (2%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGP-NGVW 448 + +L+ ++ +V+ TGAG+S +GIP FR G+W Sbjct: 4 VVELLAGARRLVIFTGAGVSAESGIPTFRDALGGLW 39 >UniRef50_Q2U9Y7 Cluster: Sirtuin 4 and related class II sirtuins; n=10; Pezizomycotina|Rep: Sirtuin 4 and related class II sirtuins - Aspergillus oryzae Length = 407 Score = 35.1 bits (77), Expect = 1.7 Identities = 14/28 (50%), Positives = 20/28 (71%) Frame = +2 Query: 377 VVHTGAGISTSAGIPDFRGPNGVWTLEK 460 V+ TGAGIS ++G+ D+RG NG + K Sbjct: 85 VLLTGAGISVASGLSDYRGENGTYVTNK 112 >UniRef50_P53686 Cluster: NAD-dependent deacetylase HST2; n=4; Saccharomyces cerevisiae|Rep: NAD-dependent deacetylase HST2 - Saccharomyces cerevisiae (Baker's yeast) Length = 357 Score = 35.1 bits (77), Expect = 1.7 Identities = 14/21 (66%), Positives = 16/21 (76%) Frame = +2 Query: 374 IVVHTGAGISTSAGIPDFRGP 436 ++ GAGISTS GIPDFR P Sbjct: 27 VIFMVGAGISTSCGIPDFRSP 47 >UniRef50_Q6AF12 Cluster: Regulatory protein, Sir2 family; n=2; Actinobacteria (class)|Rep: Regulatory protein, Sir2 family - Leifsonia xyli subsp. xyli Length = 283 Score = 34.7 bits (76), Expect = 2.2 Identities = 14/26 (53%), Positives = 18/26 (69%) Frame = +2 Query: 356 VKDSKHIVVHTGAGISTSAGIPDFRG 433 V + V TGAG+ST +GIPD+RG Sbjct: 24 VLSGRRFAVLTGAGVSTDSGIPDYRG 49 >UniRef50_Q5P3W1 Cluster: NAD-dependent deacetylase 2; n=4; Proteobacteria|Rep: NAD-dependent deacetylase 2 - Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) Length = 260 Score = 34.7 bits (76), Expect = 2.2 Identities = 14/35 (40%), Positives = 24/35 (68%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 +A+L+ + I+ TGAGIS +G+P +RG G++ Sbjct: 10 VARLIAGAPRILFITGAGISADSGLPTYRGIGGLY 44 >UniRef50_Q4XD65 Cluster: Putative uncharacterized protein; n=1; Plasmodium chabaudi|Rep: Putative uncharacterized protein - Plasmodium chabaudi Length = 177 Score = 34.7 bits (76), Expect = 2.2 Identities = 26/100 (26%), Positives = 52/100 (52%) Frame = -3 Query: 530 FKIIWVFGVVHQQMIH*WLAFYLPSLKSTLHLAL*SLEYPQKYLCQLQCGQQYVYYLSQV 351 + +W + ++ + I+ L+ YL S+ ++H+++ Y KYL C Y+ YLS Sbjct: 2 YLFVWRYIYIYIKSIY--LSIYL-SIYLSIHISI----YLSKYLSMYLCIYPYIIYLSS- 53 Query: 350 EPRVHISGSVCHLNQISLGLLVYLCFHKVIVLCIIARHFW 231 ++S S+ +S+ L ++L H I L I++ +F+ Sbjct: 54 ----YLSMSIYLSIYLSIYLSIFLSIHPSIYLSILSVYFF 89 >UniRef50_A2DKY5 Cluster: Transcriptional regulator, Sir2 family protein; n=1; Trichomonas vaginalis G3|Rep: Transcriptional regulator, Sir2 family protein - Trichomonas vaginalis G3 Length = 180 Score = 34.7 bits (76), Expect = 2.2 Identities = 17/36 (47%), Positives = 24/36 (66%), Gaps = 2/36 (5%) Frame = +2 Query: 323 LNQKCVLLAQLVKDS--KHIVVHTGAGISTSAGIPD 424 +NQ +LA L+K K++VV TG+GI + GIPD Sbjct: 1 MNQNISVLANLLKSGNYKNVVVMTGSGICNACGIPD 36 >UniRef50_A5DW75 Cluster: Putative uncharacterized protein; n=1; Lodderomyces elongisporus NRRL YB-4239|Rep: Putative uncharacterized protein - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 379 Score = 34.7 bits (76), Expect = 2.2 Identities = 14/27 (51%), Positives = 18/27 (66%) Frame = +2 Query: 368 KHIVVHTGAGISTSAGIPDFRGPNGVW 448 K IV GAG+ S+G+P FRG G+W Sbjct: 16 KKIVALVGAGLLASSGLPVFRGSQGLW 42 >UniRef50_A2QUR5 Cluster: Remark: the H. sapiens SIRT4 belongs to a group of four human SIRT proteins; n=1; Aspergillus niger|Rep: Remark: the H. sapiens SIRT4 belongs to a group of four human SIRT proteins - Aspergillus niger Length = 357 Score = 34.7 bits (76), Expect = 2.2 Identities = 14/28 (50%), Positives = 20/28 (71%) Frame = +2 Query: 377 VVHTGAGISTSAGIPDFRGPNGVWTLEK 460 V+ TGAGIS ++G+ D+RG NG + K Sbjct: 58 VLLTGAGISVASGLSDYRGENGTYITNK 85 >UniRef50_Q8F3Z6 Cluster: NAD-dependent deacetylase; n=4; Leptospira|Rep: NAD-dependent deacetylase - Leptospira interrogans Length = 246 Score = 34.7 bits (76), Expect = 2.2 Identities = 13/21 (61%), Positives = 16/21 (76%) Frame = +2 Query: 386 TGAGISTSAGIPDFRGPNGVW 448 +GAGIS +GIP FRG G+W Sbjct: 19 SGAGISAESGIPTFRGSEGLW 39 >UniRef50_Q4APN6 Cluster: Silent information regulator protein Sir2; n=1; Chlorobium phaeobacteroides BS1|Rep: Silent information regulator protein Sir2 - Chlorobium phaeobacteroides BS1 Length = 217 Score = 34.3 bits (75), Expect = 2.9 Identities = 11/21 (52%), Positives = 16/21 (76%) Frame = +2 Query: 386 TGAGISTSAGIPDFRGPNGVW 448 TGAG+S +G+P +RG G+W Sbjct: 4 TGAGMSAESGVPTYRGKGGIW 24 >UniRef50_A6Q946 Cluster: Transcriptional regulator, Sir2 family; n=1; Sulfurovum sp. NBC37-1|Rep: Transcriptional regulator, Sir2 family - Sulfurovum sp. (strain NBC37-1) Length = 271 Score = 34.3 bits (75), Expect = 2.9 Identities = 11/33 (33%), Positives = 21/33 (63%) Frame = +2 Query: 350 QLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 +++ ++ + + GAG+ +G+PDFRG G W Sbjct: 11 KVLNETDALFIMAGAGMGVDSGLPDFRGVEGFW 43 >UniRef50_A3WK56 Cluster: SIR2-like regulatory protein, NAD-dependent protein deacetylase; n=1; Idiomarina baltica OS145|Rep: SIR2-like regulatory protein, NAD-dependent protein deacetylase - Idiomarina baltica OS145 Length = 279 Score = 34.3 bits (75), Expect = 2.9 Identities = 14/37 (37%), Positives = 23/37 (62%) Frame = +2 Query: 338 VLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 V A+L++ + + +GAG+ST +GIP +R G W Sbjct: 9 VKAAELLRGNTPFTLLSGAGLSTDSGIPAYRNAQGQW 45 >UniRef50_Q54LF0 Cluster: Ankyrin repeat-containing protein; n=1; Dictyostelium discoideum AX4|Rep: Ankyrin repeat-containing protein - Dictyostelium discoideum AX4 Length = 778 Score = 34.3 bits (75), Expect = 2.9 Identities = 14/32 (43%), Positives = 23/32 (71%) Frame = +2 Query: 368 KHIVVHTGAGISTSAGIPDFRGPNGVWTLEKE 463 K+++V +GAGIS +AGIP +R +G+ K+ Sbjct: 489 KNVIVLSGAGISANAGIPPYRTKDGLLAKNKQ 520 >UniRef50_Q17JQ3 Cluster: Mitochondrial ribosomal protein, S34, putative; n=3; Endopterygota|Rep: Mitochondrial ribosomal protein, S34, putative - Aedes aegypti (Yellowfever mosquito) Length = 182 Score = 34.3 bits (75), Expect = 2.9 Identities = 15/29 (51%), Positives = 19/29 (65%) Frame = +2 Query: 431 GPNGVWTLEKEGKKPTINVSFADAQPQKP 517 G N V+ L KEG+KPTI+VS +P P Sbjct: 146 GHNNVYRLAKEGEKPTIDVSMGLGKPASP 174 >UniRef50_Q7S223 Cluster: Putative uncharacterized protein NCU05973.1; n=1; Neurospora crassa|Rep: Putative uncharacterized protein NCU05973.1 - Neurospora crassa Length = 334 Score = 34.3 bits (75), Expect = 2.9 Identities = 14/43 (32%), Positives = 25/43 (58%) Frame = +2 Query: 320 KLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 448 ++N +L K + + + GAG+S ++G+P FRG G+W Sbjct: 4 RINNLAAFHQKLAKADRILAI-CGAGLSAASGLPTFRGVGGLW 45 >UniRef50_Q2KH01 Cluster: Putative uncharacterized protein; n=2; Magnaporthe grisea|Rep: Putative uncharacterized protein - Magnaporthe grisea 70-15 Length = 449 Score = 34.3 bits (75), Expect = 2.9 Identities = 23/73 (31%), Positives = 37/73 (50%) Frame = +2 Query: 209 VPLDKLSPKNVLQLCKGLSPYENKGILGVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHT 388 +P + L K++ + C +P ++ P + D D + QL++ + VV + Sbjct: 55 LPGNSLLLKDLNRRCAASTPDRSRPSSPQPAEIDLVDAM--------QLLRSHRQTVVFS 106 Query: 389 GAGISTSAGIPDF 427 GAGIS SAGIP F Sbjct: 107 GAGISVSAGIPTF 119 >UniRef50_Q25337 Cluster: NAD-dependent deacetylase SIR2 homolog; n=6; Leishmania|Rep: NAD-dependent deacetylase SIR2 homolog - Leishmania major Length = 381 Score = 34.3 bits (75), Expect = 2.9 Identities = 15/24 (62%), Positives = 18/24 (75%) Frame = +2 Query: 359 KDSKHIVVHTGAGISTSAGIPDFR 430 KD + I+V GAG S +AGIPDFR Sbjct: 29 KDVRRILVLVGAGASVAAGIPDFR 52 >UniRef50_Q839C6 Cluster: NAD-dependent deacetylase; n=14; Bacilli|Rep: NAD-dependent deacetylase - Enterococcus faecalis (Streptococcus faecalis) Length = 237 Score = 34.3 bits (75), Expect = 2.9 Identities = 13/21 (61%), Positives = 18/21 (85%) Frame = +2 Query: 386 TGAGISTSAGIPDFRGPNGVW 448 TGAGIST++G+PD+R GV+ Sbjct: 23 TGAGISTASGVPDYRSLKGVY 43 >UniRef50_Q8A3H9 Cluster: NAD-dependent deacetylase; n=3; Bacteroides|Rep: NAD-dependent deacetylase - Bacteroides thetaiotaomicron Length = 234 Score = 34.3 bits (75), Expect = 2.9 Identities = 14/27 (51%), Positives = 19/27 (70%) Frame = +2 Query: 368 KHIVVHTGAGISTSAGIPDFRGPNGVW 448 K++VV TGAG+S +GI FR G+W Sbjct: 2 KNLVVLTGAGMSAESGISTFRDAGGLW 28 >UniRef50_A6FYM4 Cluster: Sir2 family protein; n=1; Plesiocystis pacifica SIR-1|Rep: Sir2 family protein - Plesiocystis pacifica SIR-1 Length = 297 Score = 33.9 bits (74), Expect = 3.9 Identities = 16/30 (53%), Positives = 21/30 (70%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRG 433 LA+L + +V TGAG ST +GIPD+RG Sbjct: 27 LAELCA-GRRVVALTGAGCSTESGIPDYRG 55 >UniRef50_A5K7T7 Cluster: NAD-dependent deacetylase, putative; n=5; Plasmodium|Rep: NAD-dependent deacetylase, putative - Plasmodium vivax Length = 306 Score = 33.9 bits (74), Expect = 3.9 Identities = 14/37 (37%), Positives = 23/37 (62%), Gaps = 1/37 (2%) Frame = +2 Query: 344 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPN-GVWT 451 LA +++ ++V TG+G S + IP FRG N +W+ Sbjct: 21 LACMIRGCTYVVALTGSGTSAESNIPSFRGANSSIWS 57 >UniRef50_Q8ZFR1 Cluster: NAD-dependent deacetylase; n=149; cellular organisms|Rep: NAD-dependent deacetylase - Yersinia pestis Length = 278 Score = 33.9 bits (74), Expect = 3.9 Identities = 14/25 (56%), Positives = 18/25 (72%) Frame = +2 Query: 374 IVVHTGAGISTSAGIPDFRGPNGVW 448 +VV TGAGIS +GI FR +G+W Sbjct: 41 VVVLTGAGISAESGIRTFRADDGLW 65 >UniRef50_O25849 Cluster: NAD-dependent deacetylase; n=11; Bacteria|Rep: NAD-dependent deacetylase - Helicobacter pylori (Campylobacter pylori) Length = 229 Score = 33.9 bits (74), Expect = 3.9 Identities = 13/27 (48%), Positives = 20/27 (74%) Frame = +2 Query: 368 KHIVVHTGAGISTSAGIPDFRGPNGVW 448 K++V+ +GAGIS +GI FR +G+W Sbjct: 2 KNLVILSGAGISAESGIKTFRDADGLW 28 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 711,743,914 Number of Sequences: 1657284 Number of extensions: 14796393 Number of successful extensions: 34633 Number of sequences better than 10.0: 261 Number of HSP's better than 10.0 without gapping: 33433 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 34621 length of database: 575,637,011 effective HSP length: 98 effective length of database: 413,223,179 effective search space used: 55371905986 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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