Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= e96h0045
(812 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M32721-1|AAA60155.1| 1014|Homo sapiens PPOL protein. 107 6e-23
M29786-1|AAA51663.1| 1014|Homo sapiens PPOL protein. 107 6e-23
M18112-1|AAA60137.1| 1014|Homo sapiens PPOL protein. 107 6e-23
M17081-1|AAA51599.1| 574|Homo sapiens PPOL protein. 107 6e-23
J03473-1|AAB59447.1| 1014|Homo sapiens PPOL protein. 107 6e-23
BC037545-1|AAH37545.1| 1014|Homo sapiens poly (ADP-ribose) polym... 107 6e-23
AL359742-3|CAI12102.1| 1014|Homo sapiens poly (ADP-ribose) polym... 107 6e-23
AL359704-4|CAH70215.1| 1014|Homo sapiens poly (ADP-ribose) polym... 107 6e-23
AF524947-1|AAM75364.1| 1014|Homo sapiens ADP-ribosyltransferase ... 107 6e-23
AK001980-1|BAA92017.1| 531|Homo sapiens protein ( Homo sapiens ... 77 8e-14
AJ236912-1|CAB65088.1| 570|Homo sapiens poly-(ADP-ribose) polym... 77 8e-14
AJ236876-1|CAB41505.2| 534|Homo sapiens poly(ADP-ribosyl) polym... 77 8e-14
AF479321-1|AAL77437.1| 534|Homo sapiens ADP-ribosyltransferase ... 77 8e-14
AF085734-1|AAD29857.1| 534|Homo sapiens NAD+ ADP-ribosyltransfe... 77 8e-14
Y16836-1|CAC79988.1| 540|Homo sapiens IRT1 protein protein. 72 3e-12
BC014260-1|AAH14260.1| 533|Homo sapiens poly (ADP-ribose) polym... 72 3e-12
AY126341-1|AAM95460.1| 540|Homo sapiens poly (ADP-ribose) polym... 72 3e-12
AL050034-1|CAB43246.1| 459|Homo sapiens hypothetical protein pr... 72 3e-12
AF083068-1|AAD29855.1| 533|Homo sapiens NAD+ ADP-ribosyltransfe... 72 3e-12
AB208803-1|BAD92040.1| 560|Homo sapiens poly (ADP-ribose) polym... 72 3e-12
BX255972-5|CAH73103.1| 402|Homo sapiens protein kinase C and ca... 34 0.53
BX255972-4|CAH73102.1| 444|Homo sapiens protein kinase C and ca... 34 0.53
BC128219-1|AAI28220.1| 306|Homo sapiens PACSIN1 protein protein. 34 0.53
BC040228-1|AAH40228.1| 444|Homo sapiens PACSIN1 protein protein. 34 0.53
AF242529-1|AAK29206.1| 444|Homo sapiens protein kinase C and ca... 34 0.53
AB037800-1|BAA92617.2| 457|Homo sapiens KIAA1379 protein protein. 34 0.53
BC022782-1|AAH22782.1| 780|Homo sapiens bromo adjacent homology... 30 8.7
AB023162-1|BAA76789.2| 797|Homo sapiens KIAA0945 protein protein. 30 8.7
>M32721-1|AAA60155.1| 1014|Homo sapiens PPOL protein.
Length = 1014
Score = 107 bits (256), Expect = 6e-23
Identities = 46/91 (50%), Positives = 69/91 (75%)
Frame = +1
Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
+ + +KMPLGKLSK+QI+A Y +LSE+Q + G +S ++I+D +NRF+TLIPHDF
Sbjct: 686 MVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQG-SSDSQILDLSNRFYTLIPHDF 744
Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIAY 507
G+ PLL+N + ++ K +M+DNLL+IE+AY
Sbjct: 745 GMKKPPLLNNADSVQAKVEMLDNLLDIEVAY 775
Score = 86.6 bits (205), Expect = 9e-17
Identities = 44/101 (43%), Positives = 67/101 (66%), Gaps = 1/101 (0%)
Frame = +3
Query: 510 LLQSDTDDTVS-PIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEV 686
LL+ +DD+ PI+ +Y+KLK +I +D+ ++E E+I +YV+NTH TH+ Y L V ++
Sbjct: 777 LLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHSAYDLEVIDI 836
Query: 687 FKVIREGEDKRYQALSRNSTTGRLLWHGFPQPXXFAGFISQ 809
FK+ REGE +RY+ + RLLWHG + FAG +SQ
Sbjct: 837 FKIEREGECQRYKPF-KQLHNRRLLWHG-SRTTNFAGILSQ 875
Score = 85.0 bits (201), Expect = 3e-16
Identities = 42/89 (47%), Positives = 62/89 (69%), Gaps = 4/89 (4%)
Frame = +2
Query: 11 DNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDNE--TKTLTVDP--KCELA 178
++A+++F LYEEKT N W +N F K P +++PLEIDYG +E K LTV+P K +L
Sbjct: 608 EDAIEQFMKLYEEKTGNAWHSKN-FTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLP 666
Query: 179 EPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
+PVQ LI IFD+ MK+ ++E+E+ +K
Sbjct: 667 KPVQDLIKMIFDVESMKKAMVEYEIDLQK 695
>M29786-1|AAA51663.1| 1014|Homo sapiens PPOL protein.
Length = 1014
Score = 107 bits (256), Expect = 6e-23
Identities = 46/91 (50%), Positives = 69/91 (75%)
Frame = +1
Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
+ + +KMPLGKLSK+QI+A Y +LSE+Q + G +S ++I+D +NRF+TLIPHDF
Sbjct: 686 MVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQG-SSDSQILDLSNRFYTLIPHDF 744
Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIAY 507
G+ PLL+N + ++ K +M+DNLL+IE+AY
Sbjct: 745 GMKKPPLLNNADSVQAKVEMLDNLLDIEVAY 775
Score = 88.6 bits (210), Expect = 2e-17
Identities = 45/101 (44%), Positives = 67/101 (66%), Gaps = 1/101 (0%)
Frame = +3
Query: 510 LLQSDTDDTVS-PIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEV 686
LL+ +DD+ PI+ +Y+KLK +I +D+ ++E E+I +YV+NTH THN Y L V ++
Sbjct: 777 LLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDI 836
Query: 687 FKVIREGEDKRYQALSRNSTTGRLLWHGFPQPXXFAGFISQ 809
FK+ REGE +RY+ + RLLWHG + FAG +SQ
Sbjct: 837 FKIEREGECQRYKPF-KQLHNRRLLWHG-SRTTNFAGILSQ 875
Score = 84.6 bits (200), Expect = 4e-16
Identities = 42/89 (47%), Positives = 61/89 (68%), Gaps = 4/89 (4%)
Frame = +2
Query: 11 DNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDNE--TKTLTVDP--KCELA 178
++A++ F LYEEKT N W +N F K P +++PLEIDYG +E K LTV+P K +L
Sbjct: 608 EDAIEHFMKLYEEKTGNAWHSKN-FTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLP 666
Query: 179 EPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
+PVQ LI IFD+ MK+ ++E+E+ +K
Sbjct: 667 KPVQDLIKMIFDVESMKKAMVEYEIDLQK 695
>M18112-1|AAA60137.1| 1014|Homo sapiens PPOL protein.
Length = 1014
Score = 107 bits (256), Expect = 6e-23
Identities = 46/91 (50%), Positives = 69/91 (75%)
Frame = +1
Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
+ + +KMPLGKLSK+QI+A Y +LSE+Q + G +S ++I+D +NRF+TLIPHDF
Sbjct: 686 MVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQG-SSDSQILDLSNRFYTLIPHDF 744
Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIAY 507
G+ PLL+N + ++ K +M+DNLL+IE+AY
Sbjct: 745 GMKKPPLLNNADSVQAKVEMLDNLLDIEVAY 775
Score = 88.6 bits (210), Expect = 2e-17
Identities = 45/101 (44%), Positives = 67/101 (66%), Gaps = 1/101 (0%)
Frame = +3
Query: 510 LLQSDTDDTVS-PIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEV 686
LL+ +DD+ PI+ +Y+KLK +I +D+ ++E E+I +YV+NTH THN Y L V ++
Sbjct: 777 LLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDI 836
Query: 687 FKVIREGEDKRYQALSRNSTTGRLLWHGFPQPXXFAGFISQ 809
FK+ REGE +RY+ + RLLWHG + FAG +SQ
Sbjct: 837 FKIEREGECQRYKPF-KQLHNRRLLWHG-SRTTNFAGILSQ 875
Score = 84.6 bits (200), Expect = 4e-16
Identities = 42/89 (47%), Positives = 61/89 (68%), Gaps = 4/89 (4%)
Frame = +2
Query: 11 DNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDNE--TKTLTVDP--KCELA 178
++A++ F LYEEKT N W +N F K P +++PLEIDYG +E K LTV+P K +L
Sbjct: 608 EDAIEHFMKLYEEKTGNAWHSKN-FTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLP 666
Query: 179 EPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
+PVQ LI IFD+ MK+ ++E+E+ +K
Sbjct: 667 KPVQDLIKMIFDVESMKKAMVEYEIDLQK 695
>M17081-1|AAA51599.1| 574|Homo sapiens PPOL protein.
Length = 574
Score = 107 bits (256), Expect = 6e-23
Identities = 46/91 (50%), Positives = 69/91 (75%)
Frame = +1
Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
+ + +KMPLGKLSK+QI+A Y +LSE+Q + G +S ++I+D +NRF+TLIPHDF
Sbjct: 246 MVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQG-SSDSQILDLSNRFYTLIPHDF 304
Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIAY 507
G+ PLL+N + ++ K +M+DNLL+IE+AY
Sbjct: 305 GMKKPPLLNNADSVQAKVEMLDNLLDIEVAY 335
Score = 88.6 bits (210), Expect = 2e-17
Identities = 45/101 (44%), Positives = 67/101 (66%), Gaps = 1/101 (0%)
Frame = +3
Query: 510 LLQSDTDDTVS-PIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEV 686
LL+ +DD+ PI+ +Y+KLK +I +D+ ++E E+I +YV+NTH THN Y L V ++
Sbjct: 337 LLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDI 396
Query: 687 FKVIREGEDKRYQALSRNSTTGRLLWHGFPQPXXFAGFISQ 809
FK+ REGE +RY+ + RLLWHG + FAG +SQ
Sbjct: 397 FKIEREGECQRYKPF-KQLHNRRLLWHG-SRTTNFAGILSQ 435
Score = 82.6 bits (195), Expect = 2e-15
Identities = 42/89 (47%), Positives = 60/89 (67%), Gaps = 4/89 (4%)
Frame = +2
Query: 11 DNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDNE--TKTLTVDP--KCELA 178
++A + F LYEEKT N W +N F K P +++PLEIDYG +E K LTV+P K +L
Sbjct: 168 EDANEHFMKLYEEKTGNAWHSKN-FTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLP 226
Query: 179 EPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
+PVQ LI IFD+ MK+ ++E+E+ +K
Sbjct: 227 KPVQDLIKMIFDVESMKKAMVEYEIDLQK 255
>J03473-1|AAB59447.1| 1014|Homo sapiens PPOL protein.
Length = 1014
Score = 107 bits (256), Expect = 6e-23
Identities = 46/91 (50%), Positives = 69/91 (75%)
Frame = +1
Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
+ + +KMPLGKLSK+QI+A Y +LSE+Q + G +S ++I+D +NRF+TLIPHDF
Sbjct: 686 MVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQG-SSDSQILDLSNRFYTLIPHDF 744
Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIAY 507
G+ PLL+N + ++ K +M+DNLL+IE+AY
Sbjct: 745 GMKKPPLLNNADSVQAKVEMLDNLLDIEVAY 775
Score = 88.6 bits (210), Expect = 2e-17
Identities = 45/101 (44%), Positives = 67/101 (66%), Gaps = 1/101 (0%)
Frame = +3
Query: 510 LLQSDTDDTVS-PIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEV 686
LL+ +DD+ PI+ +Y+KLK +I +D+ ++E E+I +YV+NTH THN Y L V ++
Sbjct: 777 LLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDI 836
Query: 687 FKVIREGEDKRYQALSRNSTTGRLLWHGFPQPXXFAGFISQ 809
FK+ REGE +RY+ + RLLWHG + FAG +SQ
Sbjct: 837 FKIEREGECQRYKPF-KQLHNRRLLWHG-SRTTNFAGILSQ 875
Score = 84.6 bits (200), Expect = 4e-16
Identities = 42/89 (47%), Positives = 61/89 (68%), Gaps = 4/89 (4%)
Frame = +2
Query: 11 DNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDNE--TKTLTVDP--KCELA 178
++A++ F LYEEKT N W +N F K P +++PLEIDYG +E K LTV+P K +L
Sbjct: 608 EDAIEHFMKLYEEKTGNAWHSKN-FTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLP 666
Query: 179 EPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
+PVQ LI IFD+ MK+ ++E+E+ +K
Sbjct: 667 KPVQDLIKMIFDVESMKKAMVEYEIDLQK 695
>BC037545-1|AAH37545.1| 1014|Homo sapiens poly (ADP-ribose)
polymerase family, member 1 protein.
Length = 1014
Score = 107 bits (256), Expect = 6e-23
Identities = 46/91 (50%), Positives = 69/91 (75%)
Frame = +1
Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
+ + +KMPLGKLSK+QI+A Y +LSE+Q + G +S ++I+D +NRF+TLIPHDF
Sbjct: 686 MVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQG-SSDSQILDLSNRFYTLIPHDF 744
Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIAY 507
G+ PLL+N + ++ K +M+DNLL+IE+AY
Sbjct: 745 GMKKPPLLNNADSVQAKAEMLDNLLDIEVAY 775
Score = 88.6 bits (210), Expect = 2e-17
Identities = 45/101 (44%), Positives = 67/101 (66%), Gaps = 1/101 (0%)
Frame = +3
Query: 510 LLQSDTDDTVS-PIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEV 686
LL+ +DD+ PI+ +Y+KLK +I +D+ ++E E+I +YV+NTH THN Y L V ++
Sbjct: 777 LLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDI 836
Query: 687 FKVIREGEDKRYQALSRNSTTGRLLWHGFPQPXXFAGFISQ 809
FK+ REGE +RY+ + RLLWHG + FAG +SQ
Sbjct: 837 FKIEREGECQRYKPF-KQLHNRRLLWHG-SRTTNFAGILSQ 875
Score = 84.6 bits (200), Expect = 4e-16
Identities = 42/89 (47%), Positives = 61/89 (68%), Gaps = 4/89 (4%)
Frame = +2
Query: 11 DNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDNE--TKTLTVDP--KCELA 178
++A++ F LYEEKT N W +N F K P +++PLEIDYG +E K LTV+P K +L
Sbjct: 608 EDAIEHFMKLYEEKTGNAWHSKN-FTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLP 666
Query: 179 EPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
+PVQ LI IFD+ MK+ ++E+E+ +K
Sbjct: 667 KPVQDLIKMIFDVESMKKAMVEYEIDLQK 695
>AL359742-3|CAI12102.1| 1014|Homo sapiens poly (ADP-ribose)
polymerase family, member 1 protein.
Length = 1014
Score = 107 bits (256), Expect = 6e-23
Identities = 46/91 (50%), Positives = 69/91 (75%)
Frame = +1
Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
+ + +KMPLGKLSK+QI+A Y +LSE+Q + G +S ++I+D +NRF+TLIPHDF
Sbjct: 686 MVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQG-SSDSQILDLSNRFYTLIPHDF 744
Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIAY 507
G+ PLL+N + ++ K +M+DNLL+IE+AY
Sbjct: 745 GMKKPPLLNNADSVQAKVEMLDNLLDIEVAY 775
Score = 88.6 bits (210), Expect = 2e-17
Identities = 45/101 (44%), Positives = 67/101 (66%), Gaps = 1/101 (0%)
Frame = +3
Query: 510 LLQSDTDDTVS-PIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEV 686
LL+ +DD+ PI+ +Y+KLK +I +D+ ++E E+I +YV+NTH THN Y L V ++
Sbjct: 777 LLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDI 836
Query: 687 FKVIREGEDKRYQALSRNSTTGRLLWHGFPQPXXFAGFISQ 809
FK+ REGE +RY+ + RLLWHG + FAG +SQ
Sbjct: 837 FKIEREGECQRYKPF-KQLHNRRLLWHG-SRTTNFAGILSQ 875
Score = 84.6 bits (200), Expect = 4e-16
Identities = 42/89 (47%), Positives = 61/89 (68%), Gaps = 4/89 (4%)
Frame = +2
Query: 11 DNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDNE--TKTLTVDP--KCELA 178
++A++ F LYEEKT N W +N F K P +++PLEIDYG +E K LTV+P K +L
Sbjct: 608 EDAIEHFMKLYEEKTGNAWHSKN-FTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLP 666
Query: 179 EPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
+PVQ LI IFD+ MK+ ++E+E+ +K
Sbjct: 667 KPVQDLIKMIFDVESMKKAMVEYEIDLQK 695
>AL359704-4|CAH70215.1| 1014|Homo sapiens poly (ADP-ribose)
polymerase family, member 1 protein.
Length = 1014
Score = 107 bits (256), Expect = 6e-23
Identities = 46/91 (50%), Positives = 69/91 (75%)
Frame = +1
Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
+ + +KMPLGKLSK+QI+A Y +LSE+Q + G +S ++I+D +NRF+TLIPHDF
Sbjct: 686 MVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQG-SSDSQILDLSNRFYTLIPHDF 744
Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIAY 507
G+ PLL+N + ++ K +M+DNLL+IE+AY
Sbjct: 745 GMKKPPLLNNADSVQAKVEMLDNLLDIEVAY 775
Score = 88.6 bits (210), Expect = 2e-17
Identities = 45/101 (44%), Positives = 67/101 (66%), Gaps = 1/101 (0%)
Frame = +3
Query: 510 LLQSDTDDTVS-PIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEV 686
LL+ +DD+ PI+ +Y+KLK +I +D+ ++E E+I +YV+NTH THN Y L V ++
Sbjct: 777 LLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDI 836
Query: 687 FKVIREGEDKRYQALSRNSTTGRLLWHGFPQPXXFAGFISQ 809
FK+ REGE +RY+ + RLLWHG + FAG +SQ
Sbjct: 837 FKIEREGECQRYKPF-KQLHNRRLLWHG-SRTTNFAGILSQ 875
Score = 84.6 bits (200), Expect = 4e-16
Identities = 42/89 (47%), Positives = 61/89 (68%), Gaps = 4/89 (4%)
Frame = +2
Query: 11 DNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDNE--TKTLTVDP--KCELA 178
++A++ F LYEEKT N W +N F K P +++PLEIDYG +E K LTV+P K +L
Sbjct: 608 EDAIEHFMKLYEEKTGNAWHSKN-FTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLP 666
Query: 179 EPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
+PVQ LI IFD+ MK+ ++E+E+ +K
Sbjct: 667 KPVQDLIKMIFDVESMKKAMVEYEIDLQK 695
>AF524947-1|AAM75364.1| 1014|Homo sapiens ADP-ribosyltransferase
(NAD+; poly (ADP-ribose) polymerase) protein.
Length = 1014
Score = 107 bits (256), Expect = 6e-23
Identities = 46/91 (50%), Positives = 69/91 (75%)
Frame = +1
Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
+ + +KMPLGKLSK+QI+A Y +LSE+Q + G +S ++I+D +NRF+TLIPHDF
Sbjct: 686 MVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQG-SSDSQILDLSNRFYTLIPHDF 744
Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIAY 507
G+ PLL+N + ++ K +M+DNLL+IE+AY
Sbjct: 745 GMKKPPLLNNADSVQAKVEMLDNLLDIEVAY 775
Score = 88.6 bits (210), Expect = 2e-17
Identities = 45/101 (44%), Positives = 67/101 (66%), Gaps = 1/101 (0%)
Frame = +3
Query: 510 LLQSDTDDTVS-PIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEV 686
LL+ +DD+ PI+ +Y+KLK +I +D+ ++E E+I +YV+NTH THN Y L V ++
Sbjct: 777 LLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDI 836
Query: 687 FKVIREGEDKRYQALSRNSTTGRLLWHGFPQPXXFAGFISQ 809
FK+ REGE +RY+ + RLLWHG + FAG +SQ
Sbjct: 837 FKIEREGECQRYKPF-KQLHNRRLLWHG-SRTTNFAGILSQ 875
Score = 84.6 bits (200), Expect = 4e-16
Identities = 42/89 (47%), Positives = 61/89 (68%), Gaps = 4/89 (4%)
Frame = +2
Query: 11 DNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDNE--TKTLTVDP--KCELA 178
++A++ F LYEEKT N W +N F K P +++PLEIDYG +E K LTV+P K +L
Sbjct: 608 EDAIEHFMKLYEEKTGNAWHSKN-FTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLP 666
Query: 179 EPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
+PVQ LI IFD+ MK+ ++E+E+ +K
Sbjct: 667 KPVQDLIKMIFDVESMKKAMVEYEIDLQK 695
>AK001980-1|BAA92017.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ11118 fis, clone PLACE1006011, highly similar to
Homo sapiens mRNA for poly(ADP-ribose) polymerase-2. ).
Length = 531
Score = 77.0 bits (181), Expect = 8e-14
Identities = 36/93 (38%), Positives = 60/93 (64%)
Frame = +1
Query: 226 EADLARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIP 405
E + ++ T+K PLGKL+ QIKAGY+ L ++++ I++G R +++A N F+T IP
Sbjct: 252 EEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGR-ALMEACNEFYTRIP 310
Query: 406 HDFGVNNAPLLDNNEIIKTKTDMMDNLLEIEIA 504
HDFG+ PL+ + + K +++ L +IEIA
Sbjct: 311 HDFGLRTPPLIRTQKELSEKIQLLEALGDIEIA 343
Score = 65.3 bits (152), Expect = 2e-10
Identities = 28/87 (32%), Positives = 54/87 (62%)
Frame = +3
Query: 510 LLQSDTDDTVSPIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEVF 689
L++++ P++ HY+ L + PLD + EF++I +Y+++TH TH+ YT+ + ++F
Sbjct: 346 LVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLF 405
Query: 690 KVIREGEDKRYQALSRNSTTGRLLWHG 770
+V ++GE + ++ N LLWHG
Sbjct: 406 EVEKDGEKEAFREDLHNR---MLLWHG 429
Score = 55.6 bits (128), Expect = 2e-07
Identities = 32/97 (32%), Positives = 54/97 (55%), Gaps = 10/97 (10%)
Frame = +2
Query: 5 DLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDN-----ETK-----TLT 154
+L+ A + FQ + +KT+N W+DR F K+PG+Y L++DY N ETK
Sbjct: 168 NLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSP 227
Query: 155 VDPKCELAEPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
+ P+ +L VQ LI I ++ M++ ++E + +K
Sbjct: 228 LKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKK 264
>AJ236912-1|CAB65088.1| 570|Homo sapiens poly-(ADP-ribose)
polymerase II protein.
Length = 570
Score = 77.0 bits (181), Expect = 8e-14
Identities = 36/93 (38%), Positives = 60/93 (64%)
Frame = +1
Query: 226 EADLARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIP 405
E + ++ T+K PLGKL+ QIKAGY+ L ++++ I++G R +++A N F+T IP
Sbjct: 239 EEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGR-ALMEACNEFYTRIP 297
Query: 406 HDFGVNNAPLLDNNEIIKTKTDMMDNLLEIEIA 504
HDFG+ PL+ + + K +++ L +IEIA
Sbjct: 298 HDFGLRTPPLIRTQKELSEKIQLLEALGDIEIA 330
Score = 65.3 bits (152), Expect = 2e-10
Identities = 28/87 (32%), Positives = 54/87 (62%)
Frame = +3
Query: 510 LLQSDTDDTVSPIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEVF 689
L++++ P++ HY+ L + PLD + EF++I +Y+++TH TH+ YT+ + ++F
Sbjct: 333 LVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLF 392
Query: 690 KVIREGEDKRYQALSRNSTTGRLLWHG 770
+V ++GE + ++ N LLWHG
Sbjct: 393 EVEKDGEKEAFREDLHNR---MLLWHG 416
Score = 55.6 bits (128), Expect = 2e-07
Identities = 32/97 (32%), Positives = 54/97 (55%), Gaps = 10/97 (10%)
Frame = +2
Query: 5 DLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDN-----ETK-----TLT 154
+L+ A + FQ + +KT+N W+DR F K+PG+Y L++DY N ETK
Sbjct: 155 NLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSP 214
Query: 155 VDPKCELAEPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
+ P+ +L VQ LI I ++ M++ ++E + +K
Sbjct: 215 LKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKK 251
>AJ236876-1|CAB41505.2| 534|Homo sapiens poly(ADP-ribosyl)
polymerase-2 protein.
Length = 534
Score = 77.0 bits (181), Expect = 8e-14
Identities = 36/93 (38%), Positives = 60/93 (64%)
Frame = +1
Query: 226 EADLARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIP 405
E + ++ T+K PLGKL+ QIKAGY+ L ++++ I++G R +++A N F+T IP
Sbjct: 203 EEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGR-ALMEACNEFYTRIP 261
Query: 406 HDFGVNNAPLLDNNEIIKTKTDMMDNLLEIEIA 504
HDFG+ PL+ + + K +++ L +IEIA
Sbjct: 262 HDFGLRTPPLIRTQKELSEKIQLLEALGDIEIA 294
Score = 65.3 bits (152), Expect = 2e-10
Identities = 28/87 (32%), Positives = 54/87 (62%)
Frame = +3
Query: 510 LLQSDTDDTVSPIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEVF 689
L++++ P++ HY+ L + PLD + EF++I +Y+++TH TH+ YT+ + ++F
Sbjct: 297 LVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLF 356
Query: 690 KVIREGEDKRYQALSRNSTTGRLLWHG 770
+V ++GE + ++ N LLWHG
Sbjct: 357 EVEKDGEKEAFREDLHNR---MLLWHG 380
Score = 55.6 bits (128), Expect = 2e-07
Identities = 32/97 (32%), Positives = 54/97 (55%), Gaps = 10/97 (10%)
Frame = +2
Query: 5 DLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDN-----ETK-----TLT 154
+L+ A + FQ + +KT+N W+DR F K+PG+Y L++DY N ETK
Sbjct: 119 NLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSP 178
Query: 155 VDPKCELAEPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
+ P+ +L VQ LI I ++ M++ ++E + +K
Sbjct: 179 LKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKK 215
>AF479321-1|AAL77437.1| 534|Homo sapiens ADP-ribosyltransferase
(NAD+; poly(ADP-ribose) polymerase)-like 2 protein.
Length = 534
Score = 77.0 bits (181), Expect = 8e-14
Identities = 36/93 (38%), Positives = 60/93 (64%)
Frame = +1
Query: 226 EADLARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIP 405
E + ++ T+K PLGKL+ QIKAGY+ L ++++ I++G R +++A N F+T IP
Sbjct: 203 EEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGR-ALMEACNEFYTRIP 261
Query: 406 HDFGVNNAPLLDNNEIIKTKTDMMDNLLEIEIA 504
HDFG+ PL+ + + K +++ L +IEIA
Sbjct: 262 HDFGLRTPPLIRTQKELSEKIQLLEALGDIEIA 294
Score = 65.3 bits (152), Expect = 2e-10
Identities = 28/87 (32%), Positives = 54/87 (62%)
Frame = +3
Query: 510 LLQSDTDDTVSPIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEVF 689
L++++ P++ HY+ L + PLD + EF++I +Y+++TH TH+ YT+ + ++F
Sbjct: 297 LVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLF 356
Query: 690 KVIREGEDKRYQALSRNSTTGRLLWHG 770
+V ++GE + ++ N LLWHG
Sbjct: 357 EVEKDGEKEAFREDLHNR---MLLWHG 380
Score = 55.6 bits (128), Expect = 2e-07
Identities = 32/97 (32%), Positives = 54/97 (55%), Gaps = 10/97 (10%)
Frame = +2
Query: 5 DLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDN-----ETK-----TLT 154
+L+ A + FQ + +KT+N W+DR F K+PG+Y L++DY N ETK
Sbjct: 119 NLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSP 178
Query: 155 VDPKCELAEPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
+ P+ +L VQ LI I ++ M++ ++E + +K
Sbjct: 179 LKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKK 215
>AF085734-1|AAD29857.1| 534|Homo sapiens NAD+
ADP-ribosyltransferase 2 protein.
Length = 534
Score = 77.0 bits (181), Expect = 8e-14
Identities = 36/93 (38%), Positives = 60/93 (64%)
Frame = +1
Query: 226 EADLARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIP 405
E + ++ T+K PLGKL+ QIKAGY+ L ++++ I++G R +++A N F+T IP
Sbjct: 203 EEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGR-ALMEACNEFYTRIP 261
Query: 406 HDFGVNNAPLLDNNEIIKTKTDMMDNLLEIEIA 504
HDFG+ PL+ + + K +++ L +IEIA
Sbjct: 262 HDFGLRTPPLIRTQKELSEKIQLLEALGDIEIA 294
Score = 65.3 bits (152), Expect = 2e-10
Identities = 28/87 (32%), Positives = 54/87 (62%)
Frame = +3
Query: 510 LLQSDTDDTVSPIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEVF 689
L++++ P++ HY+ L + PLD + EF++I +Y+++TH TH+ YT+ + ++F
Sbjct: 297 LVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLF 356
Query: 690 KVIREGEDKRYQALSRNSTTGRLLWHG 770
+V ++GE + ++ N LLWHG
Sbjct: 357 EVEKDGEKEAFREDLHNR---MLLWHG 380
Score = 55.6 bits (128), Expect = 2e-07
Identities = 32/97 (32%), Positives = 54/97 (55%), Gaps = 10/97 (10%)
Frame = +2
Query: 5 DLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDN-----ETK-----TLT 154
+L+ A + FQ + +KT+N W+DR F K+PG+Y L++DY N ETK
Sbjct: 119 NLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSP 178
Query: 155 VDPKCELAEPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
+ P+ +L VQ LI I ++ M++ ++E + +K
Sbjct: 179 LKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKK 215
>Y16836-1|CAC79988.1| 540|Homo sapiens IRT1 protein protein.
Length = 540
Score = 71.7 bits (168), Expect = 3e-12
Identities = 32/90 (35%), Positives = 58/90 (64%)
Frame = +1
Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
+A + + +KMPLGKLSK+QI G++ L L+ +K + + ++ F+T+IPH+F
Sbjct: 213 MALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKGPTDGGQSLEELSSHFYTVIPHNF 272
Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIA 504
G + P +++ E+++ K DM+ L +IE+A
Sbjct: 273 GHSQPPPINSPELLQAKKDMLLVLADIELA 302
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/85 (32%), Positives = 48/85 (56%)
Frame = +3
Query: 516 QSDTDDTVSPIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEVFKV 695
+ ++ P++ Y+ LK ++ LD E+++I Y+ T G H TL + ++KV
Sbjct: 312 EKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQT-GSNHRCPTL--QHIWKV 368
Query: 696 IREGEDKRYQALSRNSTTGRLLWHG 770
+EGE+ R+QA S+ +LLWHG
Sbjct: 369 NQEGEEDRFQAHSKLGNR-KLLWHG 392
Score = 49.2 bits (112), Expect = 2e-05
Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 13/99 (13%)
Frame = +2
Query: 8 LDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLE-------------IDYGDNETKT 148
L++A F+ + EKT+N W +R++FV PG+Y +E +D G T T
Sbjct: 125 LEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPVRTVT 184
Query: 149 LTVDPKCELAEPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
V P C L Q+LI IF K T+ +L +K
Sbjct: 185 KRVQP-CSLDPATQKLITNIFSKEMFKNTMALMDLDVKK 222
>BC014260-1|AAH14260.1| 533|Homo sapiens poly (ADP-ribose)
polymerase family, member 3 protein.
Length = 533
Score = 71.7 bits (168), Expect = 3e-12
Identities = 32/90 (35%), Positives = 58/90 (64%)
Frame = +1
Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
+A + + +KMPLGKLSK+QI G++ L L+ +K + + ++ F+T+IPH+F
Sbjct: 206 MALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKGPTDGGQSLEELSSHFYTVIPHNF 265
Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIA 504
G + P +++ E+++ K DM+ L +IE+A
Sbjct: 266 GHSQPPPINSPELLQAKKDMLLVLADIELA 295
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/85 (32%), Positives = 48/85 (56%)
Frame = +3
Query: 516 QSDTDDTVSPIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEVFKV 695
+ ++ P++ Y+ LK ++ LD E+++I Y+ T G H TL + ++KV
Sbjct: 305 EKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQT-GSNHRCPTL--QHIWKV 361
Query: 696 IREGEDKRYQALSRNSTTGRLLWHG 770
+EGE+ R+QA S+ +LLWHG
Sbjct: 362 NQEGEEDRFQAHSKLGNR-KLLWHG 385
Score = 49.2 bits (112), Expect = 2e-05
Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 13/99 (13%)
Frame = +2
Query: 8 LDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLE-------------IDYGDNETKT 148
L++A F+ + EKT+N W +R++FV PG+Y +E +D G T T
Sbjct: 118 LEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPVRTVT 177
Query: 149 LTVDPKCELAEPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
V P C L Q+LI IF K T+ +L +K
Sbjct: 178 KRVQP-CSLDPATQKLITNIFSKEMFKNTMALMDLDVKK 215
>AY126341-1|AAM95460.1| 540|Homo sapiens poly (ADP-ribose)
polymerase 3 protein.
Length = 540
Score = 71.7 bits (168), Expect = 3e-12
Identities = 32/90 (35%), Positives = 58/90 (64%)
Frame = +1
Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
+A + + +KMPLGKLSK+QI G++ L L+ +K + + ++ F+T+IPH+F
Sbjct: 213 MALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKGPTDGGQSLEELSSHFYTVIPHNF 272
Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIA 504
G + P +++ E+++ K DM+ L +IE+A
Sbjct: 273 GHSQPPPINSPELLQAKKDMLLVLADIELA 302
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/85 (32%), Positives = 48/85 (56%)
Frame = +3
Query: 516 QSDTDDTVSPIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEVFKV 695
+ ++ P++ Y+ LK ++ LD E+++I Y+ T G H TL + ++KV
Sbjct: 312 EKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQT-GSNHRCPTL--QHIWKV 368
Query: 696 IREGEDKRYQALSRNSTTGRLLWHG 770
+EGE+ R+QA S+ +LLWHG
Sbjct: 369 NQEGEEDRFQAHSKLGNR-KLLWHG 392
Score = 49.2 bits (112), Expect = 2e-05
Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 13/99 (13%)
Frame = +2
Query: 8 LDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLE-------------IDYGDNETKT 148
L++A F+ + EKT+N W +R++FV PG+Y +E +D G T T
Sbjct: 125 LEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPVRTVT 184
Query: 149 LTVDPKCELAEPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
V P C L Q+LI IF K T+ +L +K
Sbjct: 185 KRVQP-CSLDPATQKLITNIFSKEMFKNTMALMDLDVKK 222
>AL050034-1|CAB43246.1| 459|Homo sapiens hypothetical protein
protein.
Length = 459
Score = 71.7 bits (168), Expect = 3e-12
Identities = 32/90 (35%), Positives = 58/90 (64%)
Frame = +1
Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
+A + + +KMPLGKLSK+QI G++ L L+ +K + + ++ F+T+IPH+F
Sbjct: 132 MALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKGPTDGGQSLEELSSHFYTVIPHNF 191
Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIA 504
G + P +++ E+++ K DM+ L +IE+A
Sbjct: 192 GHSQPPPINSPELLQAKKDMLLVLADIELA 221
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/85 (32%), Positives = 48/85 (56%)
Frame = +3
Query: 516 QSDTDDTVSPIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEVFKV 695
+ ++ P++ Y+ LK ++ LD E+++I Y+ T G H TL + ++KV
Sbjct: 231 EKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQT-GSNHRCPTL--QHIWKV 287
Query: 696 IREGEDKRYQALSRNSTTGRLLWHG 770
+EGE+ R+QA S+ +LLWHG
Sbjct: 288 NQEGEEDRFQAHSKLGNR-KLLWHG 311
Score = 49.2 bits (112), Expect = 2e-05
Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 13/99 (13%)
Frame = +2
Query: 8 LDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLE-------------IDYGDNETKT 148
L++A F+ + EKT+N W +R++FV PG+Y +E +D G T T
Sbjct: 44 LEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPVRTVT 103
Query: 149 LTVDPKCELAEPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
V P C L Q+LI IF K T+ +L +K
Sbjct: 104 KRVQP-CSLDPATQKLITNIFSKEMFKNTMALMDLDVKK 141
>AF083068-1|AAD29855.1| 533|Homo sapiens NAD+
ADP-ribosyltransferase 3 protein.
Length = 533
Score = 71.7 bits (168), Expect = 3e-12
Identities = 32/90 (35%), Positives = 58/90 (64%)
Frame = +1
Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
+A + + +KMPLGKLSK+QI G++ L L+ +K + + ++ F+T+IPH+F
Sbjct: 206 MALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKGPTDGGQSLEELSSHFYTVIPHNF 265
Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIA 504
G + P +++ E+++ K DM+ L +IE+A
Sbjct: 266 GHSQPPPINSPELLQAKKDMLLVLADIELA 295
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/85 (32%), Positives = 48/85 (56%)
Frame = +3
Query: 516 QSDTDDTVSPIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEVFKV 695
+ ++ P++ Y+ LK ++ LD E+++I Y+ T G H TL + ++KV
Sbjct: 305 EKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQT-GSNHRCPTL--QHIWKV 361
Query: 696 IREGEDKRYQALSRNSTTGRLLWHG 770
+EGE+ R+QA S+ +LLWHG
Sbjct: 362 NQEGEEDRFQAHSKLGNR-KLLWHG 385
Score = 47.6 bits (108), Expect = 5e-05
Identities = 31/99 (31%), Positives = 46/99 (46%), Gaps = 13/99 (13%)
Frame = +2
Query: 8 LDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDN-------------ETKT 148
L++A F+ + EKT+N W +R++FV PG+Y +E+ D T T
Sbjct: 118 LEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRAPVRTVT 177
Query: 149 LTVDPKCELAEPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
V P C L Q+LI IF K T+ +L +K
Sbjct: 178 KRVQP-CSLDPATQKLITNIFSKEMFKNTMALMDLDVKK 215
>AB208803-1|BAD92040.1| 560|Homo sapiens poly (ADP-ribose)
polymerase family, member 3 isoform a variant protein.
Length = 560
Score = 71.7 bits (168), Expect = 3e-12
Identities = 32/90 (35%), Positives = 58/90 (64%)
Frame = +1
Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
+A + + +KMPLGKLSK+QI G++ L L+ +K + + ++ F+T+IPH+F
Sbjct: 233 MALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKGPTDGGQSLEELSSHFYTVIPHNF 292
Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIA 504
G + P +++ E+++ K DM+ L +IE+A
Sbjct: 293 GHSQPPPINSPELLQAKKDMLLVLADIELA 322
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/85 (32%), Positives = 48/85 (56%)
Frame = +3
Query: 516 QSDTDDTVSPIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEVFKV 695
+ ++ P++ Y+ LK ++ LD E+++I Y+ T G H TL + ++KV
Sbjct: 332 EKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQT-GSNHRCPTL--QHIWKV 388
Query: 696 IREGEDKRYQALSRNSTTGRLLWHG 770
+EGE+ R+QA S+ +LLWHG
Sbjct: 389 NQEGEEDRFQAHSKLGNR-KLLWHG 412
Score = 49.2 bits (112), Expect = 2e-05
Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 13/99 (13%)
Frame = +2
Query: 8 LDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLE-------------IDYGDNETKT 148
L++A F+ + EKT+N W +R++FV PG+Y +E +D G T T
Sbjct: 145 LEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPVRTVT 204
Query: 149 LTVDPKCELAEPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
V P C L Q+LI IF K T+ +L +K
Sbjct: 205 KRVQP-CSLDPATQKLITNIFSKEMFKNTMALMDLDVKK 242
>BX255972-5|CAH73103.1| 402|Homo sapiens protein kinase C and
casein kinase substrate in neurons 1 protein.
Length = 402
Score = 34.3 bits (75), Expect = 0.53
Identities = 24/73 (32%), Positives = 43/73 (58%), Gaps = 4/73 (5%)
Frame = +3
Query: 513 LQSDTDDTVSPIEGHYKKLKAEI----APLDKTTDEFEMILEYVRNTHGKTHNFYTLNVE 680
+ S T+ +V+P + KKL+ ++ + KT +++E +LE V GKT Y N+E
Sbjct: 133 MNSKTEQSVTPEQ--QKKLQDKVDKCKQDVQKTQEKYEKVLEDV----GKTTPQYMENME 186
Query: 681 EVFKVIREGEDKR 719
+VF+ ++ E+KR
Sbjct: 187 QVFEQCQQFEEKR 199
>BX255972-4|CAH73102.1| 444|Homo sapiens protein kinase C and
casein kinase substrate in neurons 1 protein.
Length = 444
Score = 34.3 bits (75), Expect = 0.53
Identities = 24/73 (32%), Positives = 43/73 (58%), Gaps = 4/73 (5%)
Frame = +3
Query: 513 LQSDTDDTVSPIEGHYKKLKAEI----APLDKTTDEFEMILEYVRNTHGKTHNFYTLNVE 680
+ S T+ +V+P + KKL+ ++ + KT +++E +LE V GKT Y N+E
Sbjct: 175 MNSKTEQSVTPEQ--QKKLQDKVDKCKQDVQKTQEKYEKVLEDV----GKTTPQYMENME 228
Query: 681 EVFKVIREGEDKR 719
+VF+ ++ E+KR
Sbjct: 229 QVFEQCQQFEEKR 241
>BC128219-1|AAI28220.1| 306|Homo sapiens PACSIN1 protein protein.
Length = 306
Score = 34.3 bits (75), Expect = 0.53
Identities = 24/73 (32%), Positives = 43/73 (58%), Gaps = 4/73 (5%)
Frame = +3
Query: 513 LQSDTDDTVSPIEGHYKKLKAEI----APLDKTTDEFEMILEYVRNTHGKTHNFYTLNVE 680
+ S T+ +V+P + KKL+ ++ + KT +++E +LE V GKT Y N+E
Sbjct: 59 MNSKTEQSVTPEQ--QKKLQDKVDKCKQDVQKTQEKYEKVLEDV----GKTTPQYMENME 112
Query: 681 EVFKVIREGEDKR 719
+VF+ ++ E+KR
Sbjct: 113 QVFEQCQQFEEKR 125
>BC040228-1|AAH40228.1| 444|Homo sapiens PACSIN1 protein protein.
Length = 444
Score = 34.3 bits (75), Expect = 0.53
Identities = 24/73 (32%), Positives = 43/73 (58%), Gaps = 4/73 (5%)
Frame = +3
Query: 513 LQSDTDDTVSPIEGHYKKLKAEI----APLDKTTDEFEMILEYVRNTHGKTHNFYTLNVE 680
+ S T+ +V+P + KKL+ ++ + KT +++E +LE V GKT Y N+E
Sbjct: 175 MNSKTEQSVTPEQ--QKKLQDKVDKCKQDVQKTQEKYEKVLEDV----GKTTPQYMENME 228
Query: 681 EVFKVIREGEDKR 719
+VF+ ++ E+KR
Sbjct: 229 QVFEQCQQFEEKR 241
>AF242529-1|AAK29206.1| 444|Homo sapiens protein kinase C and
casein kinase substrate 1 protein.
Length = 444
Score = 34.3 bits (75), Expect = 0.53
Identities = 24/73 (32%), Positives = 43/73 (58%), Gaps = 4/73 (5%)
Frame = +3
Query: 513 LQSDTDDTVSPIEGHYKKLKAEI----APLDKTTDEFEMILEYVRNTHGKTHNFYTLNVE 680
+ S T+ +V+P + KKL+ ++ + KT +++E +LE V GKT Y N+E
Sbjct: 175 MNSKTEQSVTPEQ--QKKLQDKVDKCKQDVQKTQEKYEKVLEDV----GKTTPQYMENME 228
Query: 681 EVFKVIREGEDKR 719
+VF+ ++ E+KR
Sbjct: 229 QVFEQCQQFEEKR 241
>AB037800-1|BAA92617.2| 457|Homo sapiens KIAA1379 protein protein.
Length = 457
Score = 34.3 bits (75), Expect = 0.53
Identities = 24/73 (32%), Positives = 43/73 (58%), Gaps = 4/73 (5%)
Frame = +3
Query: 513 LQSDTDDTVSPIEGHYKKLKAEI----APLDKTTDEFEMILEYVRNTHGKTHNFYTLNVE 680
+ S T+ +V+P + KKL+ ++ + KT +++E +LE V GKT Y N+E
Sbjct: 188 MNSKTEQSVTPEQ--QKKLQDKVDKCKQDVQKTQEKYEKVLEDV----GKTTPQYMENME 241
Query: 681 EVFKVIREGEDKR 719
+VF+ ++ E+KR
Sbjct: 242 QVFEQCQQFEEKR 254
>BC022782-1|AAH22782.1| 780|Homo sapiens bromo adjacent homology
domain containing 1 protein.
Length = 780
Score = 30.3 bits (65), Expect = 8.7
Identities = 13/22 (59%), Positives = 14/22 (63%)
Frame = -3
Query: 594 CRAALSPPSASCSGLRWGSPCR 529
C + PPS S SGLR GS CR
Sbjct: 535 CPQSAKPPSGSKSGLRTGSSCR 556
>AB023162-1|BAA76789.2| 797|Homo sapiens KIAA0945 protein protein.
Length = 797
Score = 30.3 bits (65), Expect = 8.7
Identities = 13/22 (59%), Positives = 14/22 (63%)
Frame = -3
Query: 594 CRAALSPPSASCSGLRWGSPCR 529
C + PPS S SGLR GS CR
Sbjct: 552 CPQSAKPPSGSKSGLRTGSSCR 573
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 112,989,408
Number of Sequences: 237096
Number of extensions: 2342757
Number of successful extensions: 5617
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 5247
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5576
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10092110758
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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