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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= e96h0045
         (812 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

M32721-1|AAA60155.1| 1014|Homo sapiens PPOL protein.                  107   6e-23
M29786-1|AAA51663.1| 1014|Homo sapiens PPOL protein.                  107   6e-23
M18112-1|AAA60137.1| 1014|Homo sapiens PPOL protein.                  107   6e-23
M17081-1|AAA51599.1|  574|Homo sapiens PPOL protein.                  107   6e-23
J03473-1|AAB59447.1| 1014|Homo sapiens PPOL protein.                  107   6e-23
BC037545-1|AAH37545.1| 1014|Homo sapiens poly (ADP-ribose) polym...   107   6e-23
AL359742-3|CAI12102.1| 1014|Homo sapiens poly (ADP-ribose) polym...   107   6e-23
AL359704-4|CAH70215.1| 1014|Homo sapiens poly (ADP-ribose) polym...   107   6e-23
AF524947-1|AAM75364.1| 1014|Homo sapiens ADP-ribosyltransferase ...   107   6e-23
AK001980-1|BAA92017.1|  531|Homo sapiens protein ( Homo sapiens ...    77   8e-14
AJ236912-1|CAB65088.1|  570|Homo sapiens poly-(ADP-ribose) polym...    77   8e-14
AJ236876-1|CAB41505.2|  534|Homo sapiens poly(ADP-ribosyl) polym...    77   8e-14
AF479321-1|AAL77437.1|  534|Homo sapiens ADP-ribosyltransferase ...    77   8e-14
AF085734-1|AAD29857.1|  534|Homo sapiens NAD+ ADP-ribosyltransfe...    77   8e-14
Y16836-1|CAC79988.1|  540|Homo sapiens IRT1 protein protein.           72   3e-12
BC014260-1|AAH14260.1|  533|Homo sapiens poly (ADP-ribose) polym...    72   3e-12
AY126341-1|AAM95460.1|  540|Homo sapiens poly (ADP-ribose) polym...    72   3e-12
AL050034-1|CAB43246.1|  459|Homo sapiens hypothetical protein pr...    72   3e-12
AF083068-1|AAD29855.1|  533|Homo sapiens NAD+ ADP-ribosyltransfe...    72   3e-12
AB208803-1|BAD92040.1|  560|Homo sapiens poly (ADP-ribose) polym...    72   3e-12
BX255972-5|CAH73103.1|  402|Homo sapiens protein kinase C and ca...    34   0.53 
BX255972-4|CAH73102.1|  444|Homo sapiens protein kinase C and ca...    34   0.53 
BC128219-1|AAI28220.1|  306|Homo sapiens PACSIN1 protein protein.      34   0.53 
BC040228-1|AAH40228.1|  444|Homo sapiens PACSIN1 protein protein.      34   0.53 
AF242529-1|AAK29206.1|  444|Homo sapiens protein kinase C and ca...    34   0.53 
AB037800-1|BAA92617.2|  457|Homo sapiens KIAA1379 protein protein.     34   0.53 
BC022782-1|AAH22782.1|  780|Homo sapiens bromo adjacent homology...    30   8.7  
AB023162-1|BAA76789.2|  797|Homo sapiens KIAA0945 protein protein.     30   8.7  

>M32721-1|AAA60155.1| 1014|Homo sapiens PPOL protein.
          Length = 1014

 Score =  107 bits (256), Expect = 6e-23
 Identities = 46/91 (50%), Positives = 69/91 (75%)
 Frame = +1

Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
           +    +  +KMPLGKLSK+QI+A Y +LSE+Q  +  G +S ++I+D +NRF+TLIPHDF
Sbjct: 686 MVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQG-SSDSQILDLSNRFYTLIPHDF 744

Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIAY 507
           G+   PLL+N + ++ K +M+DNLL+IE+AY
Sbjct: 745 GMKKPPLLNNADSVQAKVEMLDNLLDIEVAY 775



 Score = 86.6 bits (205), Expect = 9e-17
 Identities = 44/101 (43%), Positives = 67/101 (66%), Gaps = 1/101 (0%)
 Frame = +3

Query: 510  LLQSDTDDTVS-PIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEV 686
            LL+  +DD+   PI+ +Y+KLK +I  +D+ ++E E+I +YV+NTH  TH+ Y L V ++
Sbjct: 777  LLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHSAYDLEVIDI 836

Query: 687  FKVIREGEDKRYQALSRNSTTGRLLWHGFPQPXXFAGFISQ 809
            FK+ REGE +RY+   +     RLLWHG  +   FAG +SQ
Sbjct: 837  FKIEREGECQRYKPF-KQLHNRRLLWHG-SRTTNFAGILSQ 875



 Score = 85.0 bits (201), Expect = 3e-16
 Identities = 42/89 (47%), Positives = 62/89 (69%), Gaps = 4/89 (4%)
 Frame = +2

Query: 11  DNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDNE--TKTLTVDP--KCELA 178
           ++A+++F  LYEEKT N W  +N F K P +++PLEIDYG +E   K LTV+P  K +L 
Sbjct: 608 EDAIEQFMKLYEEKTGNAWHSKN-FTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLP 666

Query: 179 EPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
           +PVQ LI  IFD+  MK+ ++E+E+  +K
Sbjct: 667 KPVQDLIKMIFDVESMKKAMVEYEIDLQK 695


>M29786-1|AAA51663.1| 1014|Homo sapiens PPOL protein.
          Length = 1014

 Score =  107 bits (256), Expect = 6e-23
 Identities = 46/91 (50%), Positives = 69/91 (75%)
 Frame = +1

Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
           +    +  +KMPLGKLSK+QI+A Y +LSE+Q  +  G +S ++I+D +NRF+TLIPHDF
Sbjct: 686 MVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQG-SSDSQILDLSNRFYTLIPHDF 744

Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIAY 507
           G+   PLL+N + ++ K +M+DNLL+IE+AY
Sbjct: 745 GMKKPPLLNNADSVQAKVEMLDNLLDIEVAY 775



 Score = 88.6 bits (210), Expect = 2e-17
 Identities = 45/101 (44%), Positives = 67/101 (66%), Gaps = 1/101 (0%)
 Frame = +3

Query: 510  LLQSDTDDTVS-PIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEV 686
            LL+  +DD+   PI+ +Y+KLK +I  +D+ ++E E+I +YV+NTH  THN Y L V ++
Sbjct: 777  LLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDI 836

Query: 687  FKVIREGEDKRYQALSRNSTTGRLLWHGFPQPXXFAGFISQ 809
            FK+ REGE +RY+   +     RLLWHG  +   FAG +SQ
Sbjct: 837  FKIEREGECQRYKPF-KQLHNRRLLWHG-SRTTNFAGILSQ 875



 Score = 84.6 bits (200), Expect = 4e-16
 Identities = 42/89 (47%), Positives = 61/89 (68%), Gaps = 4/89 (4%)
 Frame = +2

Query: 11  DNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDNE--TKTLTVDP--KCELA 178
           ++A++ F  LYEEKT N W  +N F K P +++PLEIDYG +E   K LTV+P  K +L 
Sbjct: 608 EDAIEHFMKLYEEKTGNAWHSKN-FTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLP 666

Query: 179 EPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
           +PVQ LI  IFD+  MK+ ++E+E+  +K
Sbjct: 667 KPVQDLIKMIFDVESMKKAMVEYEIDLQK 695


>M18112-1|AAA60137.1| 1014|Homo sapiens PPOL protein.
          Length = 1014

 Score =  107 bits (256), Expect = 6e-23
 Identities = 46/91 (50%), Positives = 69/91 (75%)
 Frame = +1

Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
           +    +  +KMPLGKLSK+QI+A Y +LSE+Q  +  G +S ++I+D +NRF+TLIPHDF
Sbjct: 686 MVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQG-SSDSQILDLSNRFYTLIPHDF 744

Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIAY 507
           G+   PLL+N + ++ K +M+DNLL+IE+AY
Sbjct: 745 GMKKPPLLNNADSVQAKVEMLDNLLDIEVAY 775



 Score = 88.6 bits (210), Expect = 2e-17
 Identities = 45/101 (44%), Positives = 67/101 (66%), Gaps = 1/101 (0%)
 Frame = +3

Query: 510  LLQSDTDDTVS-PIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEV 686
            LL+  +DD+   PI+ +Y+KLK +I  +D+ ++E E+I +YV+NTH  THN Y L V ++
Sbjct: 777  LLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDI 836

Query: 687  FKVIREGEDKRYQALSRNSTTGRLLWHGFPQPXXFAGFISQ 809
            FK+ REGE +RY+   +     RLLWHG  +   FAG +SQ
Sbjct: 837  FKIEREGECQRYKPF-KQLHNRRLLWHG-SRTTNFAGILSQ 875



 Score = 84.6 bits (200), Expect = 4e-16
 Identities = 42/89 (47%), Positives = 61/89 (68%), Gaps = 4/89 (4%)
 Frame = +2

Query: 11  DNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDNE--TKTLTVDP--KCELA 178
           ++A++ F  LYEEKT N W  +N F K P +++PLEIDYG +E   K LTV+P  K +L 
Sbjct: 608 EDAIEHFMKLYEEKTGNAWHSKN-FTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLP 666

Query: 179 EPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
           +PVQ LI  IFD+  MK+ ++E+E+  +K
Sbjct: 667 KPVQDLIKMIFDVESMKKAMVEYEIDLQK 695


>M17081-1|AAA51599.1|  574|Homo sapiens PPOL protein.
          Length = 574

 Score =  107 bits (256), Expect = 6e-23
 Identities = 46/91 (50%), Positives = 69/91 (75%)
 Frame = +1

Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
           +    +  +KMPLGKLSK+QI+A Y +LSE+Q  +  G +S ++I+D +NRF+TLIPHDF
Sbjct: 246 MVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQG-SSDSQILDLSNRFYTLIPHDF 304

Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIAY 507
           G+   PLL+N + ++ K +M+DNLL+IE+AY
Sbjct: 305 GMKKPPLLNNADSVQAKVEMLDNLLDIEVAY 335



 Score = 88.6 bits (210), Expect = 2e-17
 Identities = 45/101 (44%), Positives = 67/101 (66%), Gaps = 1/101 (0%)
 Frame = +3

Query: 510 LLQSDTDDTVS-PIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEV 686
           LL+  +DD+   PI+ +Y+KLK +I  +D+ ++E E+I +YV+NTH  THN Y L V ++
Sbjct: 337 LLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDI 396

Query: 687 FKVIREGEDKRYQALSRNSTTGRLLWHGFPQPXXFAGFISQ 809
           FK+ REGE +RY+   +     RLLWHG  +   FAG +SQ
Sbjct: 397 FKIEREGECQRYKPF-KQLHNRRLLWHG-SRTTNFAGILSQ 435



 Score = 82.6 bits (195), Expect = 2e-15
 Identities = 42/89 (47%), Positives = 60/89 (67%), Gaps = 4/89 (4%)
 Frame = +2

Query: 11  DNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDNE--TKTLTVDP--KCELA 178
           ++A + F  LYEEKT N W  +N F K P +++PLEIDYG +E   K LTV+P  K +L 
Sbjct: 168 EDANEHFMKLYEEKTGNAWHSKN-FTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLP 226

Query: 179 EPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
           +PVQ LI  IFD+  MK+ ++E+E+  +K
Sbjct: 227 KPVQDLIKMIFDVESMKKAMVEYEIDLQK 255


>J03473-1|AAB59447.1| 1014|Homo sapiens PPOL protein.
          Length = 1014

 Score =  107 bits (256), Expect = 6e-23
 Identities = 46/91 (50%), Positives = 69/91 (75%)
 Frame = +1

Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
           +    +  +KMPLGKLSK+QI+A Y +LSE+Q  +  G +S ++I+D +NRF+TLIPHDF
Sbjct: 686 MVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQG-SSDSQILDLSNRFYTLIPHDF 744

Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIAY 507
           G+   PLL+N + ++ K +M+DNLL+IE+AY
Sbjct: 745 GMKKPPLLNNADSVQAKVEMLDNLLDIEVAY 775



 Score = 88.6 bits (210), Expect = 2e-17
 Identities = 45/101 (44%), Positives = 67/101 (66%), Gaps = 1/101 (0%)
 Frame = +3

Query: 510  LLQSDTDDTVS-PIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEV 686
            LL+  +DD+   PI+ +Y+KLK +I  +D+ ++E E+I +YV+NTH  THN Y L V ++
Sbjct: 777  LLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDI 836

Query: 687  FKVIREGEDKRYQALSRNSTTGRLLWHGFPQPXXFAGFISQ 809
            FK+ REGE +RY+   +     RLLWHG  +   FAG +SQ
Sbjct: 837  FKIEREGECQRYKPF-KQLHNRRLLWHG-SRTTNFAGILSQ 875



 Score = 84.6 bits (200), Expect = 4e-16
 Identities = 42/89 (47%), Positives = 61/89 (68%), Gaps = 4/89 (4%)
 Frame = +2

Query: 11  DNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDNE--TKTLTVDP--KCELA 178
           ++A++ F  LYEEKT N W  +N F K P +++PLEIDYG +E   K LTV+P  K +L 
Sbjct: 608 EDAIEHFMKLYEEKTGNAWHSKN-FTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLP 666

Query: 179 EPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
           +PVQ LI  IFD+  MK+ ++E+E+  +K
Sbjct: 667 KPVQDLIKMIFDVESMKKAMVEYEIDLQK 695


>BC037545-1|AAH37545.1| 1014|Homo sapiens poly (ADP-ribose)
           polymerase family, member 1 protein.
          Length = 1014

 Score =  107 bits (256), Expect = 6e-23
 Identities = 46/91 (50%), Positives = 69/91 (75%)
 Frame = +1

Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
           +    +  +KMPLGKLSK+QI+A Y +LSE+Q  +  G +S ++I+D +NRF+TLIPHDF
Sbjct: 686 MVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQG-SSDSQILDLSNRFYTLIPHDF 744

Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIAY 507
           G+   PLL+N + ++ K +M+DNLL+IE+AY
Sbjct: 745 GMKKPPLLNNADSVQAKAEMLDNLLDIEVAY 775



 Score = 88.6 bits (210), Expect = 2e-17
 Identities = 45/101 (44%), Positives = 67/101 (66%), Gaps = 1/101 (0%)
 Frame = +3

Query: 510  LLQSDTDDTVS-PIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEV 686
            LL+  +DD+   PI+ +Y+KLK +I  +D+ ++E E+I +YV+NTH  THN Y L V ++
Sbjct: 777  LLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDI 836

Query: 687  FKVIREGEDKRYQALSRNSTTGRLLWHGFPQPXXFAGFISQ 809
            FK+ REGE +RY+   +     RLLWHG  +   FAG +SQ
Sbjct: 837  FKIEREGECQRYKPF-KQLHNRRLLWHG-SRTTNFAGILSQ 875



 Score = 84.6 bits (200), Expect = 4e-16
 Identities = 42/89 (47%), Positives = 61/89 (68%), Gaps = 4/89 (4%)
 Frame = +2

Query: 11  DNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDNE--TKTLTVDP--KCELA 178
           ++A++ F  LYEEKT N W  +N F K P +++PLEIDYG +E   K LTV+P  K +L 
Sbjct: 608 EDAIEHFMKLYEEKTGNAWHSKN-FTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLP 666

Query: 179 EPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
           +PVQ LI  IFD+  MK+ ++E+E+  +K
Sbjct: 667 KPVQDLIKMIFDVESMKKAMVEYEIDLQK 695


>AL359742-3|CAI12102.1| 1014|Homo sapiens poly (ADP-ribose)
           polymerase family, member 1 protein.
          Length = 1014

 Score =  107 bits (256), Expect = 6e-23
 Identities = 46/91 (50%), Positives = 69/91 (75%)
 Frame = +1

Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
           +    +  +KMPLGKLSK+QI+A Y +LSE+Q  +  G +S ++I+D +NRF+TLIPHDF
Sbjct: 686 MVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQG-SSDSQILDLSNRFYTLIPHDF 744

Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIAY 507
           G+   PLL+N + ++ K +M+DNLL+IE+AY
Sbjct: 745 GMKKPPLLNNADSVQAKVEMLDNLLDIEVAY 775



 Score = 88.6 bits (210), Expect = 2e-17
 Identities = 45/101 (44%), Positives = 67/101 (66%), Gaps = 1/101 (0%)
 Frame = +3

Query: 510  LLQSDTDDTVS-PIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEV 686
            LL+  +DD+   PI+ +Y+KLK +I  +D+ ++E E+I +YV+NTH  THN Y L V ++
Sbjct: 777  LLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDI 836

Query: 687  FKVIREGEDKRYQALSRNSTTGRLLWHGFPQPXXFAGFISQ 809
            FK+ REGE +RY+   +     RLLWHG  +   FAG +SQ
Sbjct: 837  FKIEREGECQRYKPF-KQLHNRRLLWHG-SRTTNFAGILSQ 875



 Score = 84.6 bits (200), Expect = 4e-16
 Identities = 42/89 (47%), Positives = 61/89 (68%), Gaps = 4/89 (4%)
 Frame = +2

Query: 11  DNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDNE--TKTLTVDP--KCELA 178
           ++A++ F  LYEEKT N W  +N F K P +++PLEIDYG +E   K LTV+P  K +L 
Sbjct: 608 EDAIEHFMKLYEEKTGNAWHSKN-FTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLP 666

Query: 179 EPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
           +PVQ LI  IFD+  MK+ ++E+E+  +K
Sbjct: 667 KPVQDLIKMIFDVESMKKAMVEYEIDLQK 695


>AL359704-4|CAH70215.1| 1014|Homo sapiens poly (ADP-ribose)
           polymerase family, member 1 protein.
          Length = 1014

 Score =  107 bits (256), Expect = 6e-23
 Identities = 46/91 (50%), Positives = 69/91 (75%)
 Frame = +1

Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
           +    +  +KMPLGKLSK+QI+A Y +LSE+Q  +  G +S ++I+D +NRF+TLIPHDF
Sbjct: 686 MVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQG-SSDSQILDLSNRFYTLIPHDF 744

Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIAY 507
           G+   PLL+N + ++ K +M+DNLL+IE+AY
Sbjct: 745 GMKKPPLLNNADSVQAKVEMLDNLLDIEVAY 775



 Score = 88.6 bits (210), Expect = 2e-17
 Identities = 45/101 (44%), Positives = 67/101 (66%), Gaps = 1/101 (0%)
 Frame = +3

Query: 510  LLQSDTDDTVS-PIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEV 686
            LL+  +DD+   PI+ +Y+KLK +I  +D+ ++E E+I +YV+NTH  THN Y L V ++
Sbjct: 777  LLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDI 836

Query: 687  FKVIREGEDKRYQALSRNSTTGRLLWHGFPQPXXFAGFISQ 809
            FK+ REGE +RY+   +     RLLWHG  +   FAG +SQ
Sbjct: 837  FKIEREGECQRYKPF-KQLHNRRLLWHG-SRTTNFAGILSQ 875



 Score = 84.6 bits (200), Expect = 4e-16
 Identities = 42/89 (47%), Positives = 61/89 (68%), Gaps = 4/89 (4%)
 Frame = +2

Query: 11  DNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDNE--TKTLTVDP--KCELA 178
           ++A++ F  LYEEKT N W  +N F K P +++PLEIDYG +E   K LTV+P  K +L 
Sbjct: 608 EDAIEHFMKLYEEKTGNAWHSKN-FTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLP 666

Query: 179 EPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
           +PVQ LI  IFD+  MK+ ++E+E+  +K
Sbjct: 667 KPVQDLIKMIFDVESMKKAMVEYEIDLQK 695


>AF524947-1|AAM75364.1| 1014|Homo sapiens ADP-ribosyltransferase
           (NAD+; poly (ADP-ribose) polymerase) protein.
          Length = 1014

 Score =  107 bits (256), Expect = 6e-23
 Identities = 46/91 (50%), Positives = 69/91 (75%)
 Frame = +1

Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
           +    +  +KMPLGKLSK+QI+A Y +LSE+Q  +  G +S ++I+D +NRF+TLIPHDF
Sbjct: 686 MVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQG-SSDSQILDLSNRFYTLIPHDF 744

Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIAY 507
           G+   PLL+N + ++ K +M+DNLL+IE+AY
Sbjct: 745 GMKKPPLLNNADSVQAKVEMLDNLLDIEVAY 775



 Score = 88.6 bits (210), Expect = 2e-17
 Identities = 45/101 (44%), Positives = 67/101 (66%), Gaps = 1/101 (0%)
 Frame = +3

Query: 510  LLQSDTDDTVS-PIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEV 686
            LL+  +DD+   PI+ +Y+KLK +I  +D+ ++E E+I +YV+NTH  THN Y L V ++
Sbjct: 777  LLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDI 836

Query: 687  FKVIREGEDKRYQALSRNSTTGRLLWHGFPQPXXFAGFISQ 809
            FK+ REGE +RY+   +     RLLWHG  +   FAG +SQ
Sbjct: 837  FKIEREGECQRYKPF-KQLHNRRLLWHG-SRTTNFAGILSQ 875



 Score = 84.6 bits (200), Expect = 4e-16
 Identities = 42/89 (47%), Positives = 61/89 (68%), Gaps = 4/89 (4%)
 Frame = +2

Query: 11  DNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDNE--TKTLTVDP--KCELA 178
           ++A++ F  LYEEKT N W  +N F K P +++PLEIDYG +E   K LTV+P  K +L 
Sbjct: 608 EDAIEHFMKLYEEKTGNAWHSKN-FTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLP 666

Query: 179 EPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
           +PVQ LI  IFD+  MK+ ++E+E+  +K
Sbjct: 667 KPVQDLIKMIFDVESMKKAMVEYEIDLQK 695


>AK001980-1|BAA92017.1|  531|Homo sapiens protein ( Homo sapiens
           cDNA FLJ11118 fis, clone PLACE1006011, highly similar to
           Homo sapiens mRNA for poly(ADP-ribose) polymerase-2. ).
          Length = 531

 Score = 77.0 bits (181), Expect = 8e-14
 Identities = 36/93 (38%), Positives = 60/93 (64%)
 Frame = +1

Query: 226 EADLARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIP 405
           E  +  ++  T+K PLGKL+  QIKAGY+ L ++++ I++G   R  +++A N F+T IP
Sbjct: 252 EEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGR-ALMEACNEFYTRIP 310

Query: 406 HDFGVNNAPLLDNNEIIKTKTDMMDNLLEIEIA 504
           HDFG+   PL+   + +  K  +++ L +IEIA
Sbjct: 311 HDFGLRTPPLIRTQKELSEKIQLLEALGDIEIA 343



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 28/87 (32%), Positives = 54/87 (62%)
 Frame = +3

Query: 510 LLQSDTDDTVSPIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEVF 689
           L++++      P++ HY+ L   + PLD  + EF++I +Y+++TH  TH+ YT+ + ++F
Sbjct: 346 LVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLF 405

Query: 690 KVIREGEDKRYQALSRNSTTGRLLWHG 770
           +V ++GE + ++    N     LLWHG
Sbjct: 406 EVEKDGEKEAFREDLHNR---MLLWHG 429



 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 32/97 (32%), Positives = 54/97 (55%), Gaps = 10/97 (10%)
 Frame = +2

Query: 5   DLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDN-----ETK-----TLT 154
           +L+ A + FQ  + +KT+N W+DR  F K+PG+Y  L++DY  N     ETK        
Sbjct: 168 NLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSP 227

Query: 155 VDPKCELAEPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
           + P+ +L   VQ LI  I ++  M++ ++E +   +K
Sbjct: 228 LKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKK 264


>AJ236912-1|CAB65088.1|  570|Homo sapiens poly-(ADP-ribose)
           polymerase II protein.
          Length = 570

 Score = 77.0 bits (181), Expect = 8e-14
 Identities = 36/93 (38%), Positives = 60/93 (64%)
 Frame = +1

Query: 226 EADLARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIP 405
           E  +  ++  T+K PLGKL+  QIKAGY+ L ++++ I++G   R  +++A N F+T IP
Sbjct: 239 EEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGR-ALMEACNEFYTRIP 297

Query: 406 HDFGVNNAPLLDNNEIIKTKTDMMDNLLEIEIA 504
           HDFG+   PL+   + +  K  +++ L +IEIA
Sbjct: 298 HDFGLRTPPLIRTQKELSEKIQLLEALGDIEIA 330



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 28/87 (32%), Positives = 54/87 (62%)
 Frame = +3

Query: 510 LLQSDTDDTVSPIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEVF 689
           L++++      P++ HY+ L   + PLD  + EF++I +Y+++TH  TH+ YT+ + ++F
Sbjct: 333 LVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLF 392

Query: 690 KVIREGEDKRYQALSRNSTTGRLLWHG 770
           +V ++GE + ++    N     LLWHG
Sbjct: 393 EVEKDGEKEAFREDLHNR---MLLWHG 416



 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 32/97 (32%), Positives = 54/97 (55%), Gaps = 10/97 (10%)
 Frame = +2

Query: 5   DLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDN-----ETK-----TLT 154
           +L+ A + FQ  + +KT+N W+DR  F K+PG+Y  L++DY  N     ETK        
Sbjct: 155 NLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSP 214

Query: 155 VDPKCELAEPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
           + P+ +L   VQ LI  I ++  M++ ++E +   +K
Sbjct: 215 LKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKK 251


>AJ236876-1|CAB41505.2|  534|Homo sapiens poly(ADP-ribosyl)
           polymerase-2 protein.
          Length = 534

 Score = 77.0 bits (181), Expect = 8e-14
 Identities = 36/93 (38%), Positives = 60/93 (64%)
 Frame = +1

Query: 226 EADLARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIP 405
           E  +  ++  T+K PLGKL+  QIKAGY+ L ++++ I++G   R  +++A N F+T IP
Sbjct: 203 EEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGR-ALMEACNEFYTRIP 261

Query: 406 HDFGVNNAPLLDNNEIIKTKTDMMDNLLEIEIA 504
           HDFG+   PL+   + +  K  +++ L +IEIA
Sbjct: 262 HDFGLRTPPLIRTQKELSEKIQLLEALGDIEIA 294



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 28/87 (32%), Positives = 54/87 (62%)
 Frame = +3

Query: 510 LLQSDTDDTVSPIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEVF 689
           L++++      P++ HY+ L   + PLD  + EF++I +Y+++TH  TH+ YT+ + ++F
Sbjct: 297 LVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLF 356

Query: 690 KVIREGEDKRYQALSRNSTTGRLLWHG 770
           +V ++GE + ++    N     LLWHG
Sbjct: 357 EVEKDGEKEAFREDLHNR---MLLWHG 380



 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 32/97 (32%), Positives = 54/97 (55%), Gaps = 10/97 (10%)
 Frame = +2

Query: 5   DLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDN-----ETK-----TLT 154
           +L+ A + FQ  + +KT+N W+DR  F K+PG+Y  L++DY  N     ETK        
Sbjct: 119 NLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSP 178

Query: 155 VDPKCELAEPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
           + P+ +L   VQ LI  I ++  M++ ++E +   +K
Sbjct: 179 LKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKK 215


>AF479321-1|AAL77437.1|  534|Homo sapiens ADP-ribosyltransferase
           (NAD+; poly(ADP-ribose) polymerase)-like 2 protein.
          Length = 534

 Score = 77.0 bits (181), Expect = 8e-14
 Identities = 36/93 (38%), Positives = 60/93 (64%)
 Frame = +1

Query: 226 EADLARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIP 405
           E  +  ++  T+K PLGKL+  QIKAGY+ L ++++ I++G   R  +++A N F+T IP
Sbjct: 203 EEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGR-ALMEACNEFYTRIP 261

Query: 406 HDFGVNNAPLLDNNEIIKTKTDMMDNLLEIEIA 504
           HDFG+   PL+   + +  K  +++ L +IEIA
Sbjct: 262 HDFGLRTPPLIRTQKELSEKIQLLEALGDIEIA 294



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 28/87 (32%), Positives = 54/87 (62%)
 Frame = +3

Query: 510 LLQSDTDDTVSPIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEVF 689
           L++++      P++ HY+ L   + PLD  + EF++I +Y+++TH  TH+ YT+ + ++F
Sbjct: 297 LVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLF 356

Query: 690 KVIREGEDKRYQALSRNSTTGRLLWHG 770
           +V ++GE + ++    N     LLWHG
Sbjct: 357 EVEKDGEKEAFREDLHNR---MLLWHG 380



 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 32/97 (32%), Positives = 54/97 (55%), Gaps = 10/97 (10%)
 Frame = +2

Query: 5   DLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDN-----ETK-----TLT 154
           +L+ A + FQ  + +KT+N W+DR  F K+PG+Y  L++DY  N     ETK        
Sbjct: 119 NLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSP 178

Query: 155 VDPKCELAEPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
           + P+ +L   VQ LI  I ++  M++ ++E +   +K
Sbjct: 179 LKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKK 215


>AF085734-1|AAD29857.1|  534|Homo sapiens NAD+
           ADP-ribosyltransferase 2 protein.
          Length = 534

 Score = 77.0 bits (181), Expect = 8e-14
 Identities = 36/93 (38%), Positives = 60/93 (64%)
 Frame = +1

Query: 226 EADLARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIP 405
           E  +  ++  T+K PLGKL+  QIKAGY+ L ++++ I++G   R  +++A N F+T IP
Sbjct: 203 EEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGR-ALMEACNEFYTRIP 261

Query: 406 HDFGVNNAPLLDNNEIIKTKTDMMDNLLEIEIA 504
           HDFG+   PL+   + +  K  +++ L +IEIA
Sbjct: 262 HDFGLRTPPLIRTQKELSEKIQLLEALGDIEIA 294



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 28/87 (32%), Positives = 54/87 (62%)
 Frame = +3

Query: 510 LLQSDTDDTVSPIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEVF 689
           L++++      P++ HY+ L   + PLD  + EF++I +Y+++TH  TH+ YT+ + ++F
Sbjct: 297 LVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLF 356

Query: 690 KVIREGEDKRYQALSRNSTTGRLLWHG 770
           +V ++GE + ++    N     LLWHG
Sbjct: 357 EVEKDGEKEAFREDLHNR---MLLWHG 380



 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 32/97 (32%), Positives = 54/97 (55%), Gaps = 10/97 (10%)
 Frame = +2

Query: 5   DLDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDN-----ETK-----TLT 154
           +L+ A + FQ  + +KT+N W+DR  F K+PG+Y  L++DY  N     ETK        
Sbjct: 119 NLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSP 178

Query: 155 VDPKCELAEPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
           + P+ +L   VQ LI  I ++  M++ ++E +   +K
Sbjct: 179 LKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKK 215


>Y16836-1|CAC79988.1|  540|Homo sapiens IRT1 protein protein.
          Length = 540

 Score = 71.7 bits (168), Expect = 3e-12
 Identities = 32/90 (35%), Positives = 58/90 (64%)
 Frame = +1

Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
           +A + +  +KMPLGKLSK+QI  G++ L  L+  +K        + + ++ F+T+IPH+F
Sbjct: 213 MALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKGPTDGGQSLEELSSHFYTVIPHNF 272

Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIA 504
           G +  P +++ E+++ K DM+  L +IE+A
Sbjct: 273 GHSQPPPINSPELLQAKKDMLLVLADIELA 302



 Score = 52.4 bits (120), Expect = 2e-06
 Identities = 28/85 (32%), Positives = 48/85 (56%)
 Frame = +3

Query: 516 QSDTDDTVSPIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEVFKV 695
           +   ++   P++  Y+ LK ++  LD    E+++I  Y+  T G  H   TL  + ++KV
Sbjct: 312 EKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQT-GSNHRCPTL--QHIWKV 368

Query: 696 IREGEDKRYQALSRNSTTGRLLWHG 770
            +EGE+ R+QA S+     +LLWHG
Sbjct: 369 NQEGEEDRFQAHSKLGNR-KLLWHG 392



 Score = 49.2 bits (112), Expect = 2e-05
 Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 13/99 (13%)
 Frame = +2

Query: 8   LDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLE-------------IDYGDNETKT 148
           L++A   F+  + EKT+N W +R++FV  PG+Y  +E             +D G   T T
Sbjct: 125 LEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPVRTVT 184

Query: 149 LTVDPKCELAEPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
             V P C L    Q+LI  IF     K T+   +L  +K
Sbjct: 185 KRVQP-CSLDPATQKLITNIFSKEMFKNTMALMDLDVKK 222


>BC014260-1|AAH14260.1|  533|Homo sapiens poly (ADP-ribose)
           polymerase family, member 3 protein.
          Length = 533

 Score = 71.7 bits (168), Expect = 3e-12
 Identities = 32/90 (35%), Positives = 58/90 (64%)
 Frame = +1

Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
           +A + +  +KMPLGKLSK+QI  G++ L  L+  +K        + + ++ F+T+IPH+F
Sbjct: 206 MALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKGPTDGGQSLEELSSHFYTVIPHNF 265

Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIA 504
           G +  P +++ E+++ K DM+  L +IE+A
Sbjct: 266 GHSQPPPINSPELLQAKKDMLLVLADIELA 295



 Score = 52.4 bits (120), Expect = 2e-06
 Identities = 28/85 (32%), Positives = 48/85 (56%)
 Frame = +3

Query: 516 QSDTDDTVSPIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEVFKV 695
           +   ++   P++  Y+ LK ++  LD    E+++I  Y+  T G  H   TL  + ++KV
Sbjct: 305 EKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQT-GSNHRCPTL--QHIWKV 361

Query: 696 IREGEDKRYQALSRNSTTGRLLWHG 770
            +EGE+ R+QA S+     +LLWHG
Sbjct: 362 NQEGEEDRFQAHSKLGNR-KLLWHG 385



 Score = 49.2 bits (112), Expect = 2e-05
 Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 13/99 (13%)
 Frame = +2

Query: 8   LDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLE-------------IDYGDNETKT 148
           L++A   F+  + EKT+N W +R++FV  PG+Y  +E             +D G   T T
Sbjct: 118 LEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPVRTVT 177

Query: 149 LTVDPKCELAEPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
             V P C L    Q+LI  IF     K T+   +L  +K
Sbjct: 178 KRVQP-CSLDPATQKLITNIFSKEMFKNTMALMDLDVKK 215


>AY126341-1|AAM95460.1|  540|Homo sapiens poly (ADP-ribose)
           polymerase 3 protein.
          Length = 540

 Score = 71.7 bits (168), Expect = 3e-12
 Identities = 32/90 (35%), Positives = 58/90 (64%)
 Frame = +1

Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
           +A + +  +KMPLGKLSK+QI  G++ L  L+  +K        + + ++ F+T+IPH+F
Sbjct: 213 MALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKGPTDGGQSLEELSSHFYTVIPHNF 272

Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIA 504
           G +  P +++ E+++ K DM+  L +IE+A
Sbjct: 273 GHSQPPPINSPELLQAKKDMLLVLADIELA 302



 Score = 52.4 bits (120), Expect = 2e-06
 Identities = 28/85 (32%), Positives = 48/85 (56%)
 Frame = +3

Query: 516 QSDTDDTVSPIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEVFKV 695
           +   ++   P++  Y+ LK ++  LD    E+++I  Y+  T G  H   TL  + ++KV
Sbjct: 312 EKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQT-GSNHRCPTL--QHIWKV 368

Query: 696 IREGEDKRYQALSRNSTTGRLLWHG 770
            +EGE+ R+QA S+     +LLWHG
Sbjct: 369 NQEGEEDRFQAHSKLGNR-KLLWHG 392



 Score = 49.2 bits (112), Expect = 2e-05
 Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 13/99 (13%)
 Frame = +2

Query: 8   LDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLE-------------IDYGDNETKT 148
           L++A   F+  + EKT+N W +R++FV  PG+Y  +E             +D G   T T
Sbjct: 125 LEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPVRTVT 184

Query: 149 LTVDPKCELAEPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
             V P C L    Q+LI  IF     K T+   +L  +K
Sbjct: 185 KRVQP-CSLDPATQKLITNIFSKEMFKNTMALMDLDVKK 222


>AL050034-1|CAB43246.1|  459|Homo sapiens hypothetical protein
           protein.
          Length = 459

 Score = 71.7 bits (168), Expect = 3e-12
 Identities = 32/90 (35%), Positives = 58/90 (64%)
 Frame = +1

Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
           +A + +  +KMPLGKLSK+QI  G++ L  L+  +K        + + ++ F+T+IPH+F
Sbjct: 132 MALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKGPTDGGQSLEELSSHFYTVIPHNF 191

Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIA 504
           G +  P +++ E+++ K DM+  L +IE+A
Sbjct: 192 GHSQPPPINSPELLQAKKDMLLVLADIELA 221



 Score = 52.4 bits (120), Expect = 2e-06
 Identities = 28/85 (32%), Positives = 48/85 (56%)
 Frame = +3

Query: 516 QSDTDDTVSPIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEVFKV 695
           +   ++   P++  Y+ LK ++  LD    E+++I  Y+  T G  H   TL  + ++KV
Sbjct: 231 EKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQT-GSNHRCPTL--QHIWKV 287

Query: 696 IREGEDKRYQALSRNSTTGRLLWHG 770
            +EGE+ R+QA S+     +LLWHG
Sbjct: 288 NQEGEEDRFQAHSKLGNR-KLLWHG 311



 Score = 49.2 bits (112), Expect = 2e-05
 Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 13/99 (13%)
 Frame = +2

Query: 8   LDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLE-------------IDYGDNETKT 148
           L++A   F+  + EKT+N W +R++FV  PG+Y  +E             +D G   T T
Sbjct: 44  LEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPVRTVT 103

Query: 149 LTVDPKCELAEPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
             V P C L    Q+LI  IF     K T+   +L  +K
Sbjct: 104 KRVQP-CSLDPATQKLITNIFSKEMFKNTMALMDLDVKK 141


>AF083068-1|AAD29855.1|  533|Homo sapiens NAD+
           ADP-ribosyltransferase 3 protein.
          Length = 533

 Score = 71.7 bits (168), Expect = 3e-12
 Identities = 32/90 (35%), Positives = 58/90 (64%)
 Frame = +1

Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
           +A + +  +KMPLGKLSK+QI  G++ L  L+  +K        + + ++ F+T+IPH+F
Sbjct: 206 MALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKGPTDGGQSLEELSSHFYTVIPHNF 265

Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIA 504
           G +  P +++ E+++ K DM+  L +IE+A
Sbjct: 266 GHSQPPPINSPELLQAKKDMLLVLADIELA 295



 Score = 52.4 bits (120), Expect = 2e-06
 Identities = 28/85 (32%), Positives = 48/85 (56%)
 Frame = +3

Query: 516 QSDTDDTVSPIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEVFKV 695
           +   ++   P++  Y+ LK ++  LD    E+++I  Y+  T G  H   TL  + ++KV
Sbjct: 305 EKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQT-GSNHRCPTL--QHIWKV 361

Query: 696 IREGEDKRYQALSRNSTTGRLLWHG 770
            +EGE+ R+QA S+     +LLWHG
Sbjct: 362 NQEGEEDRFQAHSKLGNR-KLLWHG 385



 Score = 47.6 bits (108), Expect = 5e-05
 Identities = 31/99 (31%), Positives = 46/99 (46%), Gaps = 13/99 (13%)
 Frame = +2

Query: 8   LDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLEIDYGDN-------------ETKT 148
           L++A   F+  + EKT+N W +R++FV  PG+Y  +E+   D               T T
Sbjct: 118 LEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRAPVRTVT 177

Query: 149 LTVDPKCELAEPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
             V P C L    Q+LI  IF     K T+   +L  +K
Sbjct: 178 KRVQP-CSLDPATQKLITNIFSKEMFKNTMALMDLDVKK 215


>AB208803-1|BAD92040.1|  560|Homo sapiens poly (ADP-ribose)
           polymerase family, member 3 isoform a variant protein.
          Length = 560

 Score = 71.7 bits (168), Expect = 3e-12
 Identities = 32/90 (35%), Positives = 58/90 (64%)
 Frame = +1

Query: 235 LARIRVGTEKMPLGKLSKKQIKAGYKVLSELQNLIKSGDASRNKIVDATNRFFTLIPHDF 414
           +A + +  +KMPLGKLSK+QI  G++ L  L+  +K        + + ++ F+T+IPH+F
Sbjct: 233 MALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKGPTDGGQSLEELSSHFYTVIPHNF 292

Query: 415 GVNNAPLLDNNEIIKTKTDMMDNLLEIEIA 504
           G +  P +++ E+++ K DM+  L +IE+A
Sbjct: 293 GHSQPPPINSPELLQAKKDMLLVLADIELA 322



 Score = 52.4 bits (120), Expect = 2e-06
 Identities = 28/85 (32%), Positives = 48/85 (56%)
 Frame = +3

Query: 516 QSDTDDTVSPIEGHYKKLKAEIAPLDKTTDEFEMILEYVRNTHGKTHNFYTLNVEEVFKV 695
           +   ++   P++  Y+ LK ++  LD    E+++I  Y+  T G  H   TL  + ++KV
Sbjct: 332 EKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQT-GSNHRCPTL--QHIWKV 388

Query: 696 IREGEDKRYQALSRNSTTGRLLWHG 770
            +EGE+ R+QA S+     +LLWHG
Sbjct: 389 NQEGEEDRFQAHSKLGNR-KLLWHG 412



 Score = 49.2 bits (112), Expect = 2e-05
 Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 13/99 (13%)
 Frame = +2

Query: 8   LDNALDRFQALYEEKTENRWKDRNNFVKIPGRYFPLE-------------IDYGDNETKT 148
           L++A   F+  + EKT+N W +R++FV  PG+Y  +E             +D G   T T
Sbjct: 145 LEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPVRTVT 204

Query: 149 LTVDPKCELAEPVQRLIVTIFDIHYMKQTLLEFELAQRK 265
             V P C L    Q+LI  IF     K T+   +L  +K
Sbjct: 205 KRVQP-CSLDPATQKLITNIFSKEMFKNTMALMDLDVKK 242


>BX255972-5|CAH73103.1|  402|Homo sapiens protein kinase C and
           casein kinase substrate in neurons 1 protein.
          Length = 402

 Score = 34.3 bits (75), Expect = 0.53
 Identities = 24/73 (32%), Positives = 43/73 (58%), Gaps = 4/73 (5%)
 Frame = +3

Query: 513 LQSDTDDTVSPIEGHYKKLKAEI----APLDKTTDEFEMILEYVRNTHGKTHNFYTLNVE 680
           + S T+ +V+P +   KKL+ ++      + KT +++E +LE V    GKT   Y  N+E
Sbjct: 133 MNSKTEQSVTPEQ--QKKLQDKVDKCKQDVQKTQEKYEKVLEDV----GKTTPQYMENME 186

Query: 681 EVFKVIREGEDKR 719
           +VF+  ++ E+KR
Sbjct: 187 QVFEQCQQFEEKR 199


>BX255972-4|CAH73102.1|  444|Homo sapiens protein kinase C and
           casein kinase substrate in neurons 1 protein.
          Length = 444

 Score = 34.3 bits (75), Expect = 0.53
 Identities = 24/73 (32%), Positives = 43/73 (58%), Gaps = 4/73 (5%)
 Frame = +3

Query: 513 LQSDTDDTVSPIEGHYKKLKAEI----APLDKTTDEFEMILEYVRNTHGKTHNFYTLNVE 680
           + S T+ +V+P +   KKL+ ++      + KT +++E +LE V    GKT   Y  N+E
Sbjct: 175 MNSKTEQSVTPEQ--QKKLQDKVDKCKQDVQKTQEKYEKVLEDV----GKTTPQYMENME 228

Query: 681 EVFKVIREGEDKR 719
           +VF+  ++ E+KR
Sbjct: 229 QVFEQCQQFEEKR 241


>BC128219-1|AAI28220.1|  306|Homo sapiens PACSIN1 protein protein.
          Length = 306

 Score = 34.3 bits (75), Expect = 0.53
 Identities = 24/73 (32%), Positives = 43/73 (58%), Gaps = 4/73 (5%)
 Frame = +3

Query: 513 LQSDTDDTVSPIEGHYKKLKAEI----APLDKTTDEFEMILEYVRNTHGKTHNFYTLNVE 680
           + S T+ +V+P +   KKL+ ++      + KT +++E +LE V    GKT   Y  N+E
Sbjct: 59  MNSKTEQSVTPEQ--QKKLQDKVDKCKQDVQKTQEKYEKVLEDV----GKTTPQYMENME 112

Query: 681 EVFKVIREGEDKR 719
           +VF+  ++ E+KR
Sbjct: 113 QVFEQCQQFEEKR 125


>BC040228-1|AAH40228.1|  444|Homo sapiens PACSIN1 protein protein.
          Length = 444

 Score = 34.3 bits (75), Expect = 0.53
 Identities = 24/73 (32%), Positives = 43/73 (58%), Gaps = 4/73 (5%)
 Frame = +3

Query: 513 LQSDTDDTVSPIEGHYKKLKAEI----APLDKTTDEFEMILEYVRNTHGKTHNFYTLNVE 680
           + S T+ +V+P +   KKL+ ++      + KT +++E +LE V    GKT   Y  N+E
Sbjct: 175 MNSKTEQSVTPEQ--QKKLQDKVDKCKQDVQKTQEKYEKVLEDV----GKTTPQYMENME 228

Query: 681 EVFKVIREGEDKR 719
           +VF+  ++ E+KR
Sbjct: 229 QVFEQCQQFEEKR 241


>AF242529-1|AAK29206.1|  444|Homo sapiens protein kinase C and
           casein kinase substrate 1 protein.
          Length = 444

 Score = 34.3 bits (75), Expect = 0.53
 Identities = 24/73 (32%), Positives = 43/73 (58%), Gaps = 4/73 (5%)
 Frame = +3

Query: 513 LQSDTDDTVSPIEGHYKKLKAEI----APLDKTTDEFEMILEYVRNTHGKTHNFYTLNVE 680
           + S T+ +V+P +   KKL+ ++      + KT +++E +LE V    GKT   Y  N+E
Sbjct: 175 MNSKTEQSVTPEQ--QKKLQDKVDKCKQDVQKTQEKYEKVLEDV----GKTTPQYMENME 228

Query: 681 EVFKVIREGEDKR 719
           +VF+  ++ E+KR
Sbjct: 229 QVFEQCQQFEEKR 241


>AB037800-1|BAA92617.2|  457|Homo sapiens KIAA1379 protein protein.
          Length = 457

 Score = 34.3 bits (75), Expect = 0.53
 Identities = 24/73 (32%), Positives = 43/73 (58%), Gaps = 4/73 (5%)
 Frame = +3

Query: 513 LQSDTDDTVSPIEGHYKKLKAEI----APLDKTTDEFEMILEYVRNTHGKTHNFYTLNVE 680
           + S T+ +V+P +   KKL+ ++      + KT +++E +LE V    GKT   Y  N+E
Sbjct: 188 MNSKTEQSVTPEQ--QKKLQDKVDKCKQDVQKTQEKYEKVLEDV----GKTTPQYMENME 241

Query: 681 EVFKVIREGEDKR 719
           +VF+  ++ E+KR
Sbjct: 242 QVFEQCQQFEEKR 254


>BC022782-1|AAH22782.1|  780|Homo sapiens bromo adjacent homology
           domain containing 1 protein.
          Length = 780

 Score = 30.3 bits (65), Expect = 8.7
 Identities = 13/22 (59%), Positives = 14/22 (63%)
 Frame = -3

Query: 594 CRAALSPPSASCSGLRWGSPCR 529
           C  +  PPS S SGLR GS CR
Sbjct: 535 CPQSAKPPSGSKSGLRTGSSCR 556


>AB023162-1|BAA76789.2|  797|Homo sapiens KIAA0945 protein protein.
          Length = 797

 Score = 30.3 bits (65), Expect = 8.7
 Identities = 13/22 (59%), Positives = 14/22 (63%)
 Frame = -3

Query: 594 CRAALSPPSASCSGLRWGSPCR 529
           C  +  PPS S SGLR GS CR
Sbjct: 552 CPQSAKPPSGSKSGLRTGSSCR 573


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 112,989,408
Number of Sequences: 237096
Number of extensions: 2342757
Number of successful extensions: 5617
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 5247
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5576
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10092110758
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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