Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= e96h0031
(821 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q16775 Cluster: Hydroxyacylglutathione hydrolase; n=15;... 113 5e-24
UniRef50_Q99KB8 Cluster: Hydroxyacylglutathione hydrolase; n=35;... 110 4e-23
UniRef50_Q10LW8 Cluster: Hydroxyacylglutathione hydrolase, putat... 91 2e-17
UniRef50_A6NCC4 Cluster: Uncharacterized protein HAGHL; n=24; Eu... 85 2e-15
UniRef50_Q1HQH9 Cluster: Glyoxylase 3; n=3; Endopterygota|Rep: G... 81 3e-14
UniRef50_Q96BZ3 Cluster: HAGHL protein; n=2; Homo sapiens|Rep: H... 79 1e-13
UniRef50_UPI0000E244B7 Cluster: PREDICTED: similar to glyoxalase... 79 2e-13
UniRef50_P72933 Cluster: Probable hydroxyacylglutathione hydrola... 75 2e-12
UniRef50_Q1V0X4 Cluster: Hydroxyacylglutathione hydrolase cytopl... 72 2e-11
UniRef50_A7AQJ8 Cluster: Hydroxyacylglutathione hydrolase, putat... 70 8e-11
UniRef50_UPI0000E49FBF Cluster: PREDICTED: hypothetical protein,... 68 2e-10
UniRef50_Q4SBY0 Cluster: Chromosome 2 SCAF14661, whole genome sh... 66 8e-10
UniRef50_UPI0000F2E09A Cluster: PREDICTED: similar to myofibrill... 66 1e-09
UniRef50_Q4RJI5 Cluster: Chromosome 3 SCAF15037, whole genome sh... 65 2e-09
UniRef50_A7RVP5 Cluster: Predicted protein; n=1; Nematostella ve... 65 2e-09
UniRef50_Q5J7B5 Cluster: Glyoxalase IIB; n=9; Plasmodium|Rep: Gl... 64 5e-09
UniRef50_Q5KIL7 Cluster: Hydroxyacylglutathione hydrolase, putat... 63 9e-09
UniRef50_UPI0000E4A277 Cluster: PREDICTED: hypothetical protein;... 62 1e-08
UniRef50_A2R427 Cluster: Function: RSP29 precursor; n=20; Ascomy... 62 1e-08
UniRef50_Q9XXJ1 Cluster: Putative uncharacterized protein; n=2; ... 62 2e-08
UniRef50_Q2HB61 Cluster: Putative uncharacterized protein; n=1; ... 61 4e-08
UniRef50_Q8YZ99 Cluster: All0580 protein; n=6; Cyanobacteria|Rep... 60 5e-08
UniRef50_Q54MR1 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 60 5e-08
UniRef50_Q8N490-3 Cluster: Isoform 3 of Q8N490 ; n=8; Amniota|Re... 60 9e-08
UniRef50_Q8N490 Cluster: Probable hydrolase PNKD; n=25; Euteleos... 60 9e-08
UniRef50_Q9UT36 Cluster: Hydroxyacylglutathione hydrolase; n=10;... 59 1e-07
UniRef50_A6GS22 Cluster: Metallo-beta-lactamase family protein; ... 58 3e-07
UniRef50_O94250 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 56 1e-06
UniRef50_UPI0000E4A799 Cluster: PREDICTED: similar to CG4365-PC,... 55 2e-06
UniRef50_Q940L0 Cluster: Glyoxalase II; n=9; Magnoliophyta|Rep: ... 55 2e-06
UniRef50_Q4QGS1 Cluster: Hydroxyacylglutathione hydrolase, putat... 54 4e-06
UniRef50_Q1K398 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 53 8e-06
UniRef50_A0YBD1 Cluster: Metallo-beta-lactamase superfamily prot... 53 8e-06
UniRef50_A5IBE7 Cluster: Hydroxyacylglutathione hydrolase GloB; ... 52 2e-05
UniRef50_Q6F9P0 Cluster: Putative hydroxyacylglutathione hydrola... 52 2e-05
UniRef50_A4VLR2 Cluster: Hydroxyacylglutathione hydrolase; n=4; ... 51 3e-05
UniRef50_A4XU09 Cluster: Hydroxyacylglutathione hydrolase; n=2; ... 51 4e-05
UniRef50_Q5AXZ0 Cluster: Putative uncharacterized protein; n=1; ... 50 5e-05
UniRef50_A1U0V1 Cluster: Hydroxyacylglutathione hydrolase; n=3; ... 50 7e-05
UniRef50_Q4PH24 Cluster: Putative uncharacterized protein; n=1; ... 50 7e-05
UniRef50_A5WFB5 Cluster: Hydroxyacylglutathione hydrolase; n=3; ... 50 9e-05
UniRef50_UPI0000E23FD0 Cluster: PREDICTED: hydroxyacylglutathion... 49 1e-04
UniRef50_Q2BJ10 Cluster: Metallo-beta-lactamase superfamily prot... 49 1e-04
UniRef50_O24495 Cluster: Hydroxyacylglutathione hydrolase 1, mit... 49 1e-04
UniRef50_P0AC85 Cluster: Probable hydroxyacylglutathione hydrola... 49 2e-04
UniRef50_UPI0000DAE586 Cluster: hypothetical protein Rgryl_01000... 48 2e-04
UniRef50_Q01BW2 Cluster: Glyoxylase; n=2; Ostreococcus|Rep: Glyo... 48 3e-04
UniRef50_Q0F0R2 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 48 4e-04
UniRef50_Q12320 Cluster: Hydroxyacylglutathione hydrolase, mitoc... 48 4e-04
UniRef50_A5DYF9 Cluster: Hydroxyacylglutathione hydrolase; n=2; ... 47 5e-04
UniRef50_Q89XT5 Cluster: Glyoxalase II; n=16; Alphaproteobacteri... 47 7e-04
UniRef50_Q4UGN4 Cluster: Hydroxyacylglutathione hydrolase, putat... 47 7e-04
UniRef50_Q4DNS9 Cluster: Putative uncharacterized protein; n=3; ... 44 0.005
UniRef50_A6VVZ9 Cluster: Hydroxyacylglutathione hydrolase; n=2; ... 44 0.006
UniRef50_A4SXM4 Cluster: Hydroxyacylglutathione hydrolase precur... 44 0.006
UniRef50_Q7VD23 Cluster: Metallo-beta-lactamase superfamily hydr... 43 0.008
UniRef50_Q60BX0 Cluster: Metallo-beta-lactamase family protein; ... 43 0.011
UniRef50_A4C5I6 Cluster: Putative hydroxyacylglutathione hydrola... 43 0.011
UniRef50_Q1GVB7 Cluster: Hydroxyacylglutathione hydrolase precur... 42 0.014
UniRef50_A1SS88 Cluster: Hydroxyacylglutathione hydrolase; n=2; ... 42 0.019
UniRef50_Q4Q2K2 Cluster: Putative uncharacterized protein; n=3; ... 42 0.019
UniRef50_A1WFG7 Cluster: Hydroxyacylglutathione hydrolase precur... 40 0.057
UniRef50_Q581U6 Cluster: Hydroxyacylglutathione hydrolase, putat... 40 0.057
UniRef50_Q47FN7 Cluster: Beta-lactamase-like; n=1; Dechloromonas... 40 0.075
UniRef50_A7JRH0 Cluster: Hydroxyacylglutathione hydrolase; n=3; ... 40 0.075
UniRef50_Q2NGP4 Cluster: Predicted Zn-dependent hydrolase; n=1; ... 40 0.099
UniRef50_A5G655 Cluster: Beta-lactamase domain protein; n=1; Geo... 39 0.17
UniRef50_Q8FYE7 Cluster: Hydroxyacylglutathione hydrolase, putat... 38 0.23
UniRef50_A6FY39 Cluster: Probable hydroxyacylglutathione hydrola... 38 0.23
UniRef50_Q2JKB1 Cluster: Metallo-beta-lactamase domain protein; ... 38 0.30
UniRef50_UPI00006CD5DA Cluster: TNFR/NGFR cysteine-rich region f... 38 0.40
UniRef50_Q5FU83 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 38 0.40
UniRef50_Q39HP1 Cluster: Hydroxyacylglutathione hydrolase; n=55;... 38 0.40
UniRef50_Q31H51 Cluster: Metallo-beta-lactamase superfamily prot... 38 0.40
UniRef50_Q2VZH9 Cluster: Zn-dependent hydrolase, including glyox... 38 0.40
UniRef50_A0DY50 Cluster: Chromosome undetermined scaffold_7, who... 38 0.40
UniRef50_Q97GU3 Cluster: Predicted Zn-dependent hydrolase of met... 37 0.53
UniRef50_A6FA17 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 37 0.53
UniRef50_Q6ML19 Cluster: Hydroxyacylglutathione hydrolase GloB; ... 37 0.70
UniRef50_Q7MUF5 Cluster: Metallo-beta-lactamase superfamily prot... 36 0.93
UniRef50_A6FTG4 Cluster: Beta-lactamase-like protein; n=1; Roseo... 36 0.93
UniRef50_A0UWD4 Cluster: Beta-lactamase-like; n=1; Clostridium c... 36 0.93
UniRef50_Q892B0 Cluster: Hydroxyacylglutathione hydrolase; n=3; ... 36 1.2
UniRef50_Q41EG0 Cluster: Beta-lactamase-like:Rhodanese-like; n=4... 36 1.2
UniRef50_A0YF48 Cluster: Hydroxyacylglutathione hydrolase; n=2; ... 36 1.2
UniRef50_Q8EE27 Cluster: Metallo-beta-lactamase family protein; ... 36 1.6
UniRef50_Q62DP8 Cluster: Metallo-beta-lactamase family protein; ... 36 1.6
UniRef50_Q7X477 Cluster: AhlK; n=12; Proteobacteria|Rep: AhlK - ... 36 1.6
UniRef50_Q0LPD2 Cluster: Beta-lactamase-like; n=1; Herpetosiphon... 36 1.6
UniRef50_Q3SIB0 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 35 2.1
UniRef50_Q0FEW8 Cluster: Putative hydroxyacylglutathione hydrola... 35 2.1
UniRef50_A1HQX4 Cluster: Beta-lactamase domain protein; n=1; The... 35 2.1
UniRef50_Q8SSH0 Cluster: HYDROXYACYL GLUTATHION HYDROLASE; n=1; ... 35 2.1
UniRef50_Q3E6L0 Cluster: Beta-lactamase-like:Rhodanese-like; n=2... 35 2.8
UniRef50_A6DU41 Cluster: Metallo-beta-lactamase family protein; ... 35 2.8
UniRef50_Q9UZT9 Cluster: Hydroxyacylglutathione hydrolase relate... 35 2.8
UniRef50_Q8KAV6 Cluster: Hydroxyacylglutathione hydrolase, putat... 34 3.7
UniRef50_Q5LNN5 Cluster: Hydroxyacylglutathione hydrolase, putat... 34 3.7
UniRef50_Q2NVG1 Cluster: Putative hydroxyacylglutathione hydrola... 34 3.7
UniRef50_Q23CX3 Cluster: Metallo-beta-lactamase superfamily prot... 34 3.7
UniRef50_Q483N7 Cluster: Metallo-beta-lactamase family protein; ... 34 4.9
UniRef50_A6LR94 Cluster: Beta-lactamase domain protein; n=1; Clo... 34 4.9
UniRef50_A1ASA4 Cluster: Beta-lactamase domain protein; n=2; Bac... 34 4.9
UniRef50_A0L873 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 34 4.9
UniRef50_Q236K6 Cluster: Metallo-beta-lactamase superfamily prot... 34 4.9
UniRef50_A7D114 Cluster: Beta-lactamase domain protein; n=4; Hal... 34 4.9
UniRef50_Q2SJ47 Cluster: Zn-dependent Hydrolase, including glyox... 33 6.5
UniRef50_Q1NKM3 Cluster: Beta-lactamase-like; n=3; Deltaproteoba... 33 6.5
UniRef50_Q04RQ6 Cluster: Zn-dependent hydrolase; n=3; Leptospira... 33 6.5
UniRef50_A6DNT9 Cluster: Beta-lactamase-like protein; n=1; Lenti... 33 6.5
UniRef50_Q10428 Cluster: Serine/threonine-protein phosphatase 2A... 33 6.5
UniRef50_Q9AAS7 Cluster: Hydroxyacylglutathione hydrolase, putat... 33 8.6
UniRef50_Q1ARM7 Cluster: Beta-lactamase-like protein; n=1; Rubro... 33 8.6
UniRef50_A6TKP6 Cluster: Beta-lactamase domain protein; n=1; Alk... 33 8.6
UniRef50_A1U0H3 Cluster: Beta-lactamase domain protein; n=1; Mar... 33 8.6
>UniRef50_Q16775 Cluster: Hydroxyacylglutathione hydrolase; n=15;
Eukaryota|Rep: Hydroxyacylglutathione hydrolase - Homo
sapiens (Human)
Length = 260
Score = 113 bits (272), Expect = 5e-24
Identities = 72/186 (38%), Positives = 97/186 (52%), Gaps = 3/186 (1%)
Frame = +3
Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
M V++LPAL DNYMYL++D TKEAAIVDPV+P+ V+ A + GV L A
Sbjct: 1 MKVEVLPALTDNYMYLVIDDETKEAAIVDPVQPQKVVDAARKHGVKLTTVLTTHHHWDHA 60
Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLG--IYVIS 614
GGNE L+K GL VYGGDDRIG K++ + +L+ + P G Y +S
Sbjct: 61 GGNEKLVKLESGLKVYGGDDRIGALTHKITHLSTLQVGSLNVKCLATPCHTSGHICYFVS 120
Query: 615 *LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH-*MFCGHEYTLA 791
+ + GDTLF+ GCG+ C + P ++CGHEYT+
Sbjct: 121 KPGGSEPPAVFT--GDTLFVAGCGKFYEGTADEMCKALLEVLGRLPPDTRVYCGHEYTIN 178
Query: 792 GIXKFA 809
+ KFA
Sbjct: 179 NL-KFA 183
Score = 78.6 bits (185), Expect = 2e-13
Identities = 38/74 (51%), Positives = 48/74 (64%)
Frame = +2
Query: 509 ALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWA 688
ALT K+ H + ++G+LNV+CL TPCHT+GHICYFV+ P VFTG TL
Sbjct: 84 ALTHKITHLSTLQVGSLNVKCLATPCHTSGHICYFVSKPGGSEPPAVFTGD-TLFVAGCG 142
Query: 689 GSLKGTADQMYKAL 730
+GTAD+M KAL
Sbjct: 143 KFYEGTADEMCKAL 156
>UniRef50_Q99KB8 Cluster: Hydroxyacylglutathione hydrolase; n=35;
Eukaryota|Rep: Hydroxyacylglutathione hydrolase - Mus
musculus (Mouse)
Length = 260
Score = 110 bits (265), Expect = 4e-23
Identities = 72/186 (38%), Positives = 101/186 (54%), Gaps = 3/186 (1%)
Frame = +3
Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
M V++LPAL DNYMYLI+D+ T+EAAIVDPV+P+ V++A ++ V L A
Sbjct: 1 MKVELLPALTDNYMYLIIDEDTQEAAIVDPVQPQKVIEAAKKHHVKLTTVLTTHHHWDHA 60
Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*L 620
GGNE L+K PGL VYGGDDRIG K++ + +L+ + P G I
Sbjct: 61 GGNEKLVKLEPGLKVYGGDDRIGALTHKVTHLSTLQVGSLSVKCLSTPCHTSG--HICYF 118
Query: 621 LQKKVTIQLSS--PGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH-*MFCGHEYTLA 791
+ K + + S+ GDTLF+ GCG+ + P ++CGHEYT+
Sbjct: 119 VSKPGSSEPSAVFTGDTLFVAGCGKFYEGTADEMYKALLEVLGRLPPDTKVYCGHEYTVN 178
Query: 792 GIXKFA 809
+ KFA
Sbjct: 179 NL-KFA 183
Score = 83.4 bits (197), Expect = 6e-15
Identities = 40/74 (54%), Positives = 50/74 (67%)
Frame = +2
Query: 509 ALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWA 688
ALT KV H + ++G+L+V+CL TPCHT+GHICYFV+ P S VFTG TL
Sbjct: 84 ALTHKVTHLSTLQVGSLSVKCLSTPCHTSGHICYFVSKPGSSEPSAVFTGD-TLFVAGCG 142
Query: 689 GSLKGTADQMYKAL 730
+GTAD+MYKAL
Sbjct: 143 KFYEGTADEMYKAL 156
>UniRef50_Q10LW8 Cluster: Hydroxyacylglutathione hydrolase,
putative, expressed; n=3; Oryza sativa|Rep:
Hydroxyacylglutathione hydrolase, putative, expressed -
Oryza sativa subsp. japonica (Rice)
Length = 258
Score = 91.5 bits (217), Expect = 2e-17
Identities = 61/181 (33%), Positives = 89/181 (49%), Gaps = 4/181 (2%)
Frame = +3
Query: 267 VKILPA--LQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
+KI+P L+DNY YLIVD++TK AA VDPVEP+ VL A E GV + A
Sbjct: 1 MKIIPVACLEDNYAYLIVDESTKSAAAVDPVEPEKVLAAAAEVGVRIDCVLTTHHHWDHA 60
Query: 441 GGNEDLIKERPGLIVYGGD-DRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS* 617
GGNE + + PG+ VYGG D + ++ L + + LH ++
Sbjct: 61 GGNEKMAQSVPGIKVYGGSLDNVKGCTDQVENGTKLSLGKDIEILCLHTPCHTKGHISYY 120
Query: 618 LLQKKVTIQLSSPGDTLFLGGCGQVL-*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLAG 794
+ K+ GDTLF+ GCG+ A Q+ + + P ++CGHEYT+
Sbjct: 121 VTSKEEEDPAVFTGDTLFIAGCGRFFEGTAEQMYQSLCVTLGSLPKPTQVYCGHEYTVKN 180
Query: 795 I 797
+
Sbjct: 181 L 181
>UniRef50_A6NCC4 Cluster: Uncharacterized protein HAGHL; n=24;
Euteleostomi|Rep: Uncharacterized protein HAGHL - Homo
sapiens (Human)
Length = 291
Score = 85.4 bits (202), Expect = 2e-15
Identities = 56/179 (31%), Positives = 83/179 (46%)
Frame = +3
Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
M VK++P L+DNYMYL++++ T+EA VD PK +L+ V +GV+L A
Sbjct: 1 MKVKVIPVLEDNYMYLVIEELTREAVAVDVAVPKRLLEIVGREGVSLTAVLTTHHHWDHA 60
Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*L 620
GN +L + RPGL V G D+RI ++L+ + L+ L P G
Sbjct: 61 RGNPELARLRPGLAVLGADERIFSLTRRLAHGEELRFGAIHVRCLLTPGHTAGHMSYFLW 120
Query: 621 LQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLAGI 797
GD L + GCG L + Q + +FCGHE+TL+ +
Sbjct: 121 EDDCPDPPALFSGDALSVAGCGSCLEGSAQQMYQSLAELGTLPPETKVFCGHEHTLSNL 179
Score = 54.8 bits (126), Expect = 2e-06
Identities = 28/80 (35%), Positives = 48/80 (60%), Gaps = 1/80 (1%)
Frame = +2
Query: 509 ALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWA 688
+LT+++ H + + G ++V+CL TP HT GH+ YF+ + + +F+G L
Sbjct: 84 SLTRRLAHGEELRFGAIHVRCLLTPGHTAGHMSYFLWEDDCPDPPALFSG--DALSVAGC 141
Query: 689 GS-LKGTADQMYKALTILSS 745
GS L+G+A QMY++L L +
Sbjct: 142 GSCLEGSAQQMYQSLAELGT 161
>UniRef50_Q1HQH9 Cluster: Glyoxylase 3; n=3; Endopterygota|Rep:
Glyoxylase 3 - Aedes aegypti (Yellowfever mosquito)
Length = 302
Score = 81.0 bits (191), Expect = 3e-14
Identities = 66/187 (35%), Positives = 88/187 (47%), Gaps = 11/187 (5%)
Frame = +3
Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
M VK +PAL+DN+MYL+V TK AAIVDPVEP VL+ +E GV+L A
Sbjct: 43 MTVKKIPALKDNFMYLVVCNETKNAAIVDPVEPDRVLQVAKESGVSLNKVLTTHHHWDHA 102
Query: 441 GGNEDLIKERPG------LIVYGG-DDRIGPSQKKL---STIQSLKSVT*MYSVFLHPVI 590
GGN DL K L +YGG D+RI + T++ S H
Sbjct: 103 GGNADLFKRYQADTSLGPLQIYGGNDERIDNLTNPVGQDDTLEIGNLKVRCISTPCHTTS 162
Query: 591 QLGIYVIS*LLQKKVTIQLSSPGDTLFLGGCGQVL-*RARQIKCTKH*QF*AAA*PH*MF 767
+ Y+ + + KV GDTLFL GCG+ +Q+ + A ++
Sbjct: 163 HICYYIET--PEDKVVF----TGDTLFLAGCGRFFEGTPQQMYDALITKLSALPDDTKVY 216
Query: 768 CGHEYTL 788
CGHEY L
Sbjct: 217 CGHEYAL 223
Score = 70.9 bits (166), Expect = 4e-11
Identities = 38/80 (47%), Positives = 45/80 (56%)
Frame = +2
Query: 512 LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAG 691
LT V + +IGNL V+C+ TPCHTT HICY++ PE D VVFTG TL
Sbjct: 134 LTNPVGQDDTLEIGNLKVRCISTPCHTTSHICYYIETPE---DKVVFTGD-TLFLAGCGR 189
Query: 692 SLKGTADQMYKALTILSSCL 751
+GT QMY AL S L
Sbjct: 190 FFEGTPQQMYDALITKLSAL 209
>UniRef50_Q96BZ3 Cluster: HAGHL protein; n=2; Homo sapiens|Rep:
HAGHL protein - Homo sapiens (Human)
Length = 203
Score = 79.0 bits (186), Expect = 1e-13
Identities = 38/96 (39%), Positives = 58/96 (60%)
Frame = +3
Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
M VK++P L+DNYMYL++++ T+EA VD PK +L+ V +GV+L A
Sbjct: 1 MKVKVIPVLEDNYMYLVIEELTREAVAVDVAVPKRLLEIVGREGVSLTAVLTTHHHWDHA 60
Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLK 548
GN +L + RPGL V G D+RI ++L+ + L+
Sbjct: 61 RGNPELARLRPGLAVLGADERIFSLTRRLAHGEELR 96
>UniRef50_UPI0000E244B7 Cluster: PREDICTED: similar to glyoxalase
II, partial; n=1; Pan troglodytes|Rep: PREDICTED:
similar to glyoxalase II, partial - Pan troglodytes
Length = 284
Score = 78.6 bits (185), Expect = 2e-13
Identities = 38/74 (51%), Positives = 48/74 (64%)
Frame = +2
Query: 509 ALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWA 688
ALT K+ H + ++G+LNV+CL TPCHT+GHICYFV+ P VFTG TL
Sbjct: 27 ALTHKITHLSTLQVGSLNVKCLATPCHTSGHICYFVSKPGGSEPPAVFTGD-TLFVAGCG 85
Query: 689 GSLKGTADQMYKAL 730
+GTAD+M KAL
Sbjct: 86 KFYEGTADEMCKAL 99
Score = 54.8 bits (126), Expect = 2e-06
Identities = 42/127 (33%), Positives = 61/127 (48%), Gaps = 3/127 (2%)
Frame = +3
Query: 438 AGGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLG--IYVI 611
AGGNE L++ + GL VYGGDDRIG K++ + +L+ + P G Y +
Sbjct: 3 AGGNEKLVELQSGLKVYGGDDRIGALTHKITHLSTLQVGSLNVKCLATPCHTSGHICYFV 62
Query: 612 S*LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH-*MFCGHEYTL 788
S + + GDTLF+ GCG+ C + P ++CGHEYT+
Sbjct: 63 SKPGGSEPPAVFT--GDTLFVAGCGKFYEGTADEMCKALLEVLGRLPPDTRVYCGHEYTI 120
Query: 789 AGIXKFA 809
+ KFA
Sbjct: 121 NNL-KFA 126
>UniRef50_P72933 Cluster: Probable hydroxyacylglutathione hydrolase;
n=13; Bacteria|Rep: Probable hydroxyacylglutathione
hydrolase - Synechocystis sp. (strain PCC 6803)
Length = 257
Score = 74.9 bits (176), Expect = 2e-12
Identities = 60/186 (32%), Positives = 81/186 (43%), Gaps = 3/186 (1%)
Frame = +3
Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
MD+ LPAL DNY++L+ D+ +AA+VDP E K VL +E G +L
Sbjct: 1 MDIHRLPALADNYIFLLHDRQRNQAAVVDPAEAKPVLDCLETLGADLVTIYNTHHHGDHV 60
Query: 441 GGNEDLIKERPGLIVYGGDDRIG--PSQKK-LSTIQSLKSVT*MYSVFLHPVIQLGIYVI 611
G N +L+ + P L VYGG + G P Q L L +V+ P G
Sbjct: 61 GANRELLAKYPNLEVYGGVEDQGRIPGQTVFLRDGDRLSFADREATVYFVPGHTRGHIAY 120
Query: 612 S*LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLA 791
TI GDT+F GGCG++ + ++C HEYTL
Sbjct: 121 YFAPGSGETIGDLFCGDTIFAGGCGRLFEGTPAQMVQSIGKLRQLPDQTRLWCAHEYTL- 179
Query: 792 GIXKFA 809
G KFA
Sbjct: 180 GNLKFA 185
>UniRef50_Q1V0X4 Cluster: Hydroxyacylglutathione hydrolase
cytoplasmic; n=2; Candidatus Pelagibacter ubique|Rep:
Hydroxyacylglutathione hydrolase cytoplasmic -
Candidatus Pelagibacter ubique HTCC1002
Length = 239
Score = 71.7 bits (168), Expect = 2e-11
Identities = 57/178 (32%), Positives = 82/178 (46%), Gaps = 3/178 (1%)
Frame = +3
Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
M+++I+ LQDNY YLIVDKA A ++DP E K V+K +E++ ++L
Sbjct: 1 MEIQIIRCLQDNYSYLIVDKAKNIACVIDPSEAKPVIKYLEDKNIHLKYILNTHHHYDHV 60
Query: 441 GGNEDLIKERPG--LIVYGGD-DRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVI 611
GGN++L KE+ G +I Y GD DRI + +F P LG
Sbjct: 61 GGNKEL-KEKYGASVIGYKGDKDRIPEIDILVGDQDIWHEENFQAKIFHIPGHTLGHICF 119
Query: 612 S*LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYT 785
++ V GDTLF GCG++ + A ++CGHEYT
Sbjct: 120 YFYNEESV-----FTGDTLFSLGCGKIFEGTYSQMYNSLMKIKALPEKTKIYCGHEYT 172
Score = 35.1 bits (77), Expect = 2.1
Identities = 24/85 (28%), Positives = 35/85 (41%)
Frame = +2
Query: 554 NLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGSLKGTADQMYKALT 733
N + P HT GHIC++ N+ VFTG TL +GT QMY +L
Sbjct: 101 NFQAKIFHIPGHTLGHICFYFY-----NEESVFTGD-TLFSLGCGKIFEGTYSQMYNSLM 154
Query: 734 ILSSCLTTLNVLWP*VHFGRNXKIC 808
+ + + + +N K C
Sbjct: 155 KIKALPEKTKIYCGHEYTKQNSKFC 179
>UniRef50_A7AQJ8 Cluster: Hydroxyacylglutathione hydrolase,
putative; n=1; Babesia bovis|Rep: Hydroxyacylglutathione
hydrolase, putative - Babesia bovis
Length = 319
Score = 69.7 bits (163), Expect = 8e-11
Identities = 54/189 (28%), Positives = 87/189 (46%), Gaps = 5/189 (2%)
Frame = +3
Query: 264 DVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAG 443
+V +P QDNY Y++VD K A VDP EP+ +L ++E+ + L +G
Sbjct: 68 EVITVPLFQDNYGYIVVDPDGKHAFCVDPAEPRKILSVIDERKLTLKAVFCTHKHHDHSG 127
Query: 444 GNEDLIKERPGLIVYG--GDDRIGPSQKKL-STIQSLKSVT*M-YSVFLHPVIQLGIYVI 611
GN ++ + PG+ VYG +D G + + + L + V H + + YV
Sbjct: 128 GNLEMARIIPGIPVYGSNNEDMAGMTNGIMDGDVVRLGGLEIKGVRVPCHTLGHMLYYVT 187
Query: 612 S*LLQKKVTIQ-LSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTL 788
+ T+Q L GDT+F+GGCG+ + ++CGHEYT+
Sbjct: 188 N---PSDPTMQPLMFTGDTIFIGGCGRFFEGTADMMLNIMNTVRQYRKDSLIYCGHEYTV 244
Query: 789 AGIXKFAGS 815
+ KFA +
Sbjct: 245 KNL-KFAST 252
Score = 42.3 bits (95), Expect = 0.014
Identities = 20/69 (28%), Positives = 33/69 (47%)
Frame = +2
Query: 512 LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAG 691
+T + ++G L ++ + PCHT GH+ Y+VT P + + G T+
Sbjct: 152 MTNGIMDGDVVRLGGLEIKGVRVPCHTLGHMLYYVTNPSDPTMQPLMFTGDTIFIGGCGR 211
Query: 692 SLKGTADQM 718
+GTAD M
Sbjct: 212 FFEGTADMM 220
>UniRef50_UPI0000E49FBF Cluster: PREDICTED: hypothetical protein,
partial; n=3; Strongylocentrotus purpuratus|Rep:
PREDICTED: hypothetical protein, partial -
Strongylocentrotus purpuratus
Length = 268
Score = 68.1 bits (159), Expect = 2e-10
Identities = 44/142 (30%), Positives = 72/142 (50%), Gaps = 3/142 (2%)
Frame = +3
Query: 276 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 455
+P L+DNY YL+++KA+ AA++DP + + V + +E+Q V L +GGN+
Sbjct: 6 IPYLKDNYAYLVIEKASNIAAVIDPGDAEAVQRVIEQQNVQLTAILTTHKHWDHSGGNQK 65
Query: 456 LIKERPGLIVYGGD-DRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLG--IYVIS*LLQ 626
L L VYGG+ D + KL S + ++ P +G +Y++
Sbjct: 66 LKSLHSNLAVYGGERDGVPGCNHKLKDGDSFQIGGLKFTALFTPGHTVGHMVYLLD-RSD 124
Query: 627 KKVTIQLSSPGDTLFLGGCGQV 692
K + L + GD LFLGG G++
Sbjct: 125 KNLPNSLFT-GDILFLGGNGRM 145
>UniRef50_Q4SBY0 Cluster: Chromosome 2 SCAF14661, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 2
SCAF14661, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 400
Score = 66.5 bits (155), Expect = 8e-10
Identities = 48/145 (33%), Positives = 67/145 (46%), Gaps = 5/145 (3%)
Frame = +3
Query: 267 VKILP--ALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
+KI+P L DNY YL++D A A +VDP +P+TV ++E+GV L +
Sbjct: 55 IKIIPISVLSDNYSYLVIDTAAGVAVVVDPADPQTVQAVIKEEGVVLEAILCTHKHWDHS 114
Query: 441 GGNEDLIKERPGLIVYG-GDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS* 617
GGN++L K VYG D I LS S+ + P +G +
Sbjct: 115 GGNKELKKLHTSCRVYGSATDNIPGLTHPLSHRDSIAFGRLHFEALFTPGHTVGHMIY-- 172
Query: 618 LLQKKVTIQLSS--PGDTLFLGGCG 686
LL + SS GD +FL GCG
Sbjct: 173 LLDGRTVGSPSSLFSGDLVFLSGCG 197
>UniRef50_UPI0000F2E09A Cluster: PREDICTED: similar to
myofibrillogenesis regulator 1; n=1; Monodelphis
domestica|Rep: PREDICTED: similar to myofibrillogenesis
regulator 1 - Monodelphis domestica
Length = 286
Score = 65.7 bits (153), Expect = 1e-09
Identities = 49/145 (33%), Positives = 65/145 (44%), Gaps = 5/145 (3%)
Frame = +3
Query: 267 VKILP--ALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
VK+LP L DNY YLI+D +K A VDP +P+ V A+E++GV L +
Sbjct: 49 VKVLPIPVLLDNYSYLIIDTQSKLAVAVDPSDPRAVQAAIEKEGVTLVAILCTHKHWDHS 108
Query: 441 GGNEDLIKERPGLIVYGG-DDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLG--IYVI 611
GGN +L + G VYG D I L + + P G +YV+
Sbjct: 109 GGNRELRRHHRGCRVYGNPQDGIAHLTHPLCHQDMVSVGRLQFQALATPGHTRGHMVYVL 168
Query: 612 S*LLQKKVTIQLSSPGDTLFLGGCG 686
K + S GD LFL GCG
Sbjct: 169 DGEPYKGPSCLFS--GDLLFLSGCG 191
>UniRef50_Q4RJI5 Cluster: Chromosome 3 SCAF15037, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 3 SCAF15037, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 227
Score = 65.3 bits (152), Expect = 2e-09
Identities = 29/47 (61%), Positives = 39/47 (82%)
Frame = +3
Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNL 401
M V++LPAL DNYMYL+VD ++EAA+VDPVEP V++AV++ GV L
Sbjct: 49 MRVELLPALSDNYMYLLVDVESREAAVVDPVEPLKVVEAVKKHGVRL 95
>UniRef50_A7RVP5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 318
Score = 64.9 bits (151), Expect = 2e-09
Identities = 47/147 (31%), Positives = 70/147 (47%), Gaps = 8/147 (5%)
Frame = +3
Query: 276 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 455
+P L DNY Y+IVD T A +VDP +P+ V + ++ + L +GGN
Sbjct: 56 VPFLYDNYSYIIVDITTSSAVVVDPSDPEAVKDVLNKEKLQLEAVLTTHKHWDHSGGNTS 115
Query: 456 LIKERPGLIVYGG--DDRIG--PSQKKLSTIQSL--KSVT*MYSVFLHPVIQLG--IYVI 611
L + P + VYG DD G ++K L I + K ++ F P G +Y++
Sbjct: 116 LKADFPSVAVYGSELDDAPGLTHTRKPLCDISNFSGKVSQLSFTAFSTPGHTAGHVVYLL 175
Query: 612 S*LLQKKVTIQLSSPGDTLFLGGCGQV 692
+ V S GD LFLGGCG++
Sbjct: 176 HGAVFNSVDSLFS--GDLLFLGGCGRI 200
>UniRef50_Q5J7B5 Cluster: Glyoxalase IIB; n=9; Plasmodium|Rep:
Glyoxalase IIB - Plasmodium falciparum
Length = 263
Score = 63.7 bits (148), Expect = 5e-09
Identities = 53/188 (28%), Positives = 83/188 (44%), Gaps = 7/188 (3%)
Frame = +3
Query: 267 VKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGG 446
V ++P L DN+ Y+I+D+ TK+AA +DPVEP VLK +E V L +GG
Sbjct: 7 VLVVPVLNDNFSYVIIDEKTKKAASIDPVEPDKVLKRIETANVELEYVLCTHHHYDHSGG 66
Query: 447 NEDLIKERPGLIVYGGDDRIGPS-QKKLSTIQSLKSVT*MYSVFLHPVIQLG--IYVIS* 617
N + + + + V G P +K+ Q ++ P G +Y +
Sbjct: 67 NIRMRELKQNIKVVGSAYEPTPGVNEKVYDGQIIRLGELNIKAIHAPCHTKGHILYYVYK 126
Query: 618 LLQKKVTIQLSSP----GDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYT 785
+ K P GDTLF+ GCG+ + + + ++CGHEYT
Sbjct: 127 TDEAKQEDHKYKPILFTGDTLFIAGCGRFFEGSAKDMFKNIEKVKNMRKETLIYCGHEYT 186
Query: 786 LAGIXKFA 809
L + +FA
Sbjct: 187 LNNL-RFA 193
Score = 44.0 bits (99), Expect = 0.005
Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 6/77 (7%)
Frame = +2
Query: 512 LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDS------VVFTGGYTLL 673
+ +KV ++G LN++ + PCHT GHI Y+V +E ++FTG TL
Sbjct: 90 VNEKVYDGQIIRLGELNIKAIHAPCHTKGHILYYVYKTDEAKQEDHKYKPILFTGD-TLF 148
Query: 674 RRMWAGSLKGTADQMYK 724
+G+A M+K
Sbjct: 149 IAGCGRFFEGSAKDMFK 165
>UniRef50_Q5KIL7 Cluster: Hydroxyacylglutathione hydrolase,
putative; n=1; Filobasidiella neoformans|Rep:
Hydroxyacylglutathione hydrolase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 274
Score = 62.9 bits (146), Expect = 9e-09
Identities = 44/143 (30%), Positives = 65/143 (45%), Gaps = 2/143 (1%)
Frame = +3
Query: 267 VKILP--ALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
+K+LP A DN+MYLI+D ++ EAA+VDP + + AV+EQ N+ +
Sbjct: 25 MKVLPYKARSDNWMYLIID-SSNEAAVVDPYDANKISGAVKEQRANVTSLITTHHHADHS 83
Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*L 620
GGN + P L VY G + + + + + LH + L
Sbjct: 84 GGNSKFLSLHPNLKVYAGSTQSPGTNTVVKDGDTFTLGQDITVKCLHTPCHTQDSICFFL 143
Query: 621 LQKKVTIQLSSPGDTLFLGGCGQ 689
KK + GDTLFL GCG+
Sbjct: 144 EDKKTGQRGVFTGDTLFLAGCGR 166
>UniRef50_UPI0000E4A277 Cluster: PREDICTED: hypothetical protein;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 280
Score = 62.5 bits (145), Expect = 1e-08
Identities = 31/93 (33%), Positives = 52/93 (55%), Gaps = 1/93 (1%)
Frame = +3
Query: 252 VKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXX 431
V+ + + +P L+DNY YL+++KA+ AA++DP + + V + +E+Q V L
Sbjct: 39 VEGVIILPIPYLKDNYAYLVIEKASNIAAVIDPGDAEAVQRVIEQQNVQLTAILTTHKHW 98
Query: 432 XXAGGNEDLIKERPGLIVYGGD-DRIGPSQKKL 527
+GGN+ L L VYGG+ D + +KL
Sbjct: 99 DHSGGNQTLKSLHSNLAVYGGERDGVPGCNRKL 131
>UniRef50_A2R427 Cluster: Function: RSP29 precursor; n=20;
Ascomycota|Rep: Function: RSP29 precursor - Aspergillus
niger
Length = 299
Score = 62.5 bits (145), Expect = 1e-08
Identities = 39/103 (37%), Positives = 57/103 (55%), Gaps = 2/103 (1%)
Frame = +2
Query: 506 RALTKKVEHNTKFKIGN-LNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRM 682
+++TK H FKIG ++V+ L TPCHT ICYF+ ++G+D VVFTG TL
Sbjct: 133 QSVTKTPAHGEVFKIGERISVKALHTPCHTQDSICYFM---QDGDDKVVFTGD-TLFIGG 188
Query: 683 WAGSLKGTADQMYKALTILSSCLTTLNVLWP*VHFGR-NXKIC 808
+GTA +M+KAL + L ++P + + N K C
Sbjct: 189 CGRFFEGTAPEMHKALNETLAALPDDTKVYPGHEYTKGNVKFC 231
Score = 46.8 bits (106), Expect = 7e-04
Identities = 39/138 (28%), Positives = 59/138 (42%), Gaps = 5/138 (3%)
Frame = +3
Query: 291 DNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQ----GVNLXXXXXXXXXXXXAGGNEDL 458
+NY YL+ D+ TKE+ I+DP P V ++ Q + L AGGN ++
Sbjct: 58 NNYAYLVTDEPTKESVIIDPANPPEVAPTLKSQIDAGKIKLTSIVNTHHHWDHAGGNNEI 117
Query: 459 IKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSV-FLHPVIQLGIYVIS*LLQKKV 635
+K L V GG + S K + + SV LH + +
Sbjct: 118 LKTFGQLSVIGGKN--CQSVTKTPAHGEVFKIGERISVKALHTPCHTQDSIC--YFMQDG 173
Query: 636 TIQLSSPGDTLFLGGCGQ 689
++ GDTLF+GGCG+
Sbjct: 174 DDKVVFTGDTLFIGGCGR 191
>UniRef50_Q9XXJ1 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 260
Score = 61.7 bits (143), Expect = 2e-08
Identities = 35/91 (38%), Positives = 48/91 (52%), Gaps = 2/91 (2%)
Frame = +2
Query: 509 ALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDS--VVFTGGYTLLRRM 682
A+ + V+H + L ++CL TPCHT+GHICY +T P + S VVFTG TL
Sbjct: 86 AMDRHVKHGDMAEFAGLQIKCLSTPCHTSGHICYHITNPAADSTSPGVVFTGD-TLFIAG 144
Query: 683 WAGSLKGTADQMYKALTILSSCLTTLNVLWP 775
+GTA QM AL + L ++P
Sbjct: 145 CGRFFEGTAPQMDVALNEILKNLPVETQIFP 175
Score = 50.0 bits (114), Expect = 7e-05
Identities = 46/185 (24%), Positives = 77/185 (41%), Gaps = 4/185 (2%)
Frame = +3
Query: 267 VKILPALQDNYMYLIVDKATKEAAI-VDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAG 443
VK L DN+MY++ + AA+ VD V + + +++ +++ G
Sbjct: 4 VKSLLRRADNFMYIVKKSSEARAALLVDLVNEEDYKELADKENIDITAVLTTHHHYDHCG 63
Query: 444 GNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLG--IYVIS* 617
GNE ++ P +++ GGD RI + + + P G Y I+
Sbjct: 64 GNEGFRRQFPNVMILGGDSRIPAMDRHVKHGDMAEFAGLQIKCLSTPCHTSGHICYHITN 123
Query: 618 LLQKKVTIQLSSPGDTLFLGGCGQVL-*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLAG 794
+ + GDTLF+ GCG+ A Q+ + +F GHEYT+A
Sbjct: 124 PAADSTSPGVVFTGDTLFIAGCGRFFEGTAPQMDVALNEILKNLPVETQIFPGHEYTVAN 183
Query: 795 IXKFA 809
+ KFA
Sbjct: 184 L-KFA 187
>UniRef50_Q2HB61 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 722
Score = 60.9 bits (141), Expect = 4e-08
Identities = 31/77 (40%), Positives = 45/77 (58%)
Frame = +2
Query: 506 RALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMW 685
+ +TK H F IG++ V+ L TPCHT IC+F+ ++GND VVFTG TL
Sbjct: 543 KKVTKTPPHGATFNIGDIAVKALHTPCHTQDSICFFM---QDGNDKVVFTGD-TLFHGGE 598
Query: 686 AGSLKGTADQMYKALTI 736
+G ++M+KAL +
Sbjct: 599 FLFFEGNGEEMHKALNV 615
Score = 36.7 bits (81), Expect = 0.70
Identities = 13/23 (56%), Positives = 17/23 (73%)
Frame = +3
Query: 291 DNYMYLIVDKATKEAAIVDPVEP 359
DNY YL+VD +KEA ++DP P
Sbjct: 491 DNYAYLVVDDKSKEAVVIDPAHP 513
>UniRef50_Q8YZ99 Cluster: All0580 protein; n=6; Cyanobacteria|Rep:
All0580 protein - Anabaena sp. (strain PCC 7120)
Length = 257
Score = 60.5 bits (140), Expect = 5e-08
Identities = 55/185 (29%), Positives = 77/185 (41%), Gaps = 6/185 (3%)
Frame = +3
Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
M V L AL DNY++L+ D AA+VDP E + VLK + + L
Sbjct: 1 MQVIRLAALSDNYIFLLHDSHKNIAAVVDPAEAEPVLKQLAQLKAELVAIFNTHHHNDHV 60
Query: 441 GGNEDLIKERPGLIVYGGDDRIG--PSQKKL----STIQSLKSVT*MYSVFLHPVIQLGI 602
GGN+ LI++ P + VYGG G P Q+ +Q V + V H +
Sbjct: 61 GGNQKLIQKFPQVKVYGGAKDQGRIPGQQVFLQPGDRVQFADRVAEVIFVPGHTRAHIAY 120
Query: 603 YVIS*LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEY 782
Y Q T GDTLF GGCG++ + + ++C HEY
Sbjct: 121 YFPP---QTDDTPGELFCGDTLFAGGCGRLFEGTPAQMVESLTKLRSLPENTRVWCAHEY 177
Query: 783 TLAGI 797
TL +
Sbjct: 178 TLKNL 182
>UniRef50_Q54MR1 Cluster: Hydroxyacylglutathione hydrolase; n=1;
Dictyostelium discoideum AX4|Rep: Hydroxyacylglutathione
hydrolase - Dictyostelium discoideum AX4
Length = 268
Score = 60.5 bits (140), Expect = 5e-08
Identities = 43/148 (29%), Positives = 68/148 (45%), Gaps = 6/148 (4%)
Frame = +3
Query: 267 VKILPAL--QDNYMYLIVDKATKEAAIVDPVEPKTVLKAVE--EQGVNLXXXXXXXXXXX 434
+K+ P L +DNY YL++D+ K A +DP EP V+ ++ + +
Sbjct: 1 MKVQPVLVNKDNYSYLVIDEKNKVAIAIDPCEPNKVISSLSSISSDIKINSVFTTHHHWD 60
Query: 435 XAGGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS 614
AGGN + + VYG D+R KKL + LK + P +V+
Sbjct: 61 HAGGNNLIKTIIKDINVYGRDERFEGITKKLENNEVLKIGSLKIKTLDAPA-HTSSHVLY 119
Query: 615 *LLQKKVTIQLSS--PGDTLFLGGCGQV 692
+ + Q+ S GDTLF+GGCG++
Sbjct: 120 LIEDENEPNQVKSLFTGDTLFIGGCGRL 147
Score = 51.6 bits (118), Expect = 2e-05
Identities = 26/73 (35%), Positives = 37/73 (50%)
Frame = +2
Query: 512 LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAG 691
+TKK+E+N KIG+L ++ L P HT+ H+ Y + E N G TL
Sbjct: 87 ITKKLENNEVLKIGSLKIKTLDAPAHTSSHVLYLIEDENEPNQVKSLFTGDTLFIGGCGR 146
Query: 692 SLKGTADQMYKAL 730
+G +QMY AL
Sbjct: 147 LFEGNPEQMYNAL 159
>UniRef50_Q8N490-3 Cluster: Isoform 3 of Q8N490 ; n=8; Amniota|Rep:
Isoform 3 of Q8N490 - Homo sapiens (Human)
Length = 361
Score = 59.7 bits (138), Expect = 9e-08
Identities = 47/146 (32%), Positives = 65/146 (44%), Gaps = 5/146 (3%)
Frame = +3
Query: 267 VKILP--ALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
VK+LP L DNY YLI+D + A VDP +P+ V ++E++GV L +
Sbjct: 95 VKVLPIPVLSDNYSYLIIDTQAQLAVAVDPSDPRAVQASIEKEGVTLVAILCTHKHWDHS 154
Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*M-YSVFLHPVIQLG--IYVI 611
GGN DL + VYG P Q + SV + P G +Y++
Sbjct: 155 GGNRDLSRRHRDCRVYGSPQDGIPYLTHPLCHQDVVSVGRLQIRALATPGHTQGHLVYLL 214
Query: 612 S*LLQKKVTIQLSSPGDTLFLGGCGQ 689
K + S GD LFL GCG+
Sbjct: 215 DGEPYKGPSCLFS--GDLLFLSGCGR 238
Score = 42.3 bits (95), Expect = 0.014
Identities = 28/89 (31%), Positives = 41/89 (46%), Gaps = 1/89 (1%)
Frame = +2
Query: 512 LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAG 691
LT + H +G L ++ L TP HT GH+ Y + S +F+G L
Sbjct: 180 LTHPLCHQDVVSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFSGDLLFLSGC-GR 238
Query: 692 SLKGTADQMYKAL-TILSSCLTTLNVLWP 775
+ +G A+ M +L T+L TL LWP
Sbjct: 239 TFEGNAETMLSSLDTVLGLGDDTL--LWP 265
>UniRef50_Q8N490 Cluster: Probable hydrolase PNKD; n=25;
Euteleostomi|Rep: Probable hydrolase PNKD - Homo sapiens
(Human)
Length = 385
Score = 59.7 bits (138), Expect = 9e-08
Identities = 47/146 (32%), Positives = 65/146 (44%), Gaps = 5/146 (3%)
Frame = +3
Query: 267 VKILP--ALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
VK+LP L DNY YLI+D + A VDP +P+ V ++E++GV L +
Sbjct: 119 VKVLPIPVLSDNYSYLIIDTQAQLAVAVDPSDPRAVQASIEKEGVTLVAILCTHKHWDHS 178
Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*M-YSVFLHPVIQLG--IYVI 611
GGN DL + VYG P Q + SV + P G +Y++
Sbjct: 179 GGNRDLSRRHRDCRVYGSPQDGIPYLTHPLCHQDVVSVGRLQIRALATPGHTQGHLVYLL 238
Query: 612 S*LLQKKVTIQLSSPGDTLFLGGCGQ 689
K + S GD LFL GCG+
Sbjct: 239 DGEPYKGPSCLFS--GDLLFLSGCGR 262
Score = 42.3 bits (95), Expect = 0.014
Identities = 28/89 (31%), Positives = 41/89 (46%), Gaps = 1/89 (1%)
Frame = +2
Query: 512 LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAG 691
LT + H +G L ++ L TP HT GH+ Y + S +F+G L
Sbjct: 204 LTHPLCHQDVVSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFSGDLLFLSGC-GR 262
Query: 692 SLKGTADQMYKAL-TILSSCLTTLNVLWP 775
+ +G A+ M +L T+L TL LWP
Sbjct: 263 TFEGNAETMLSSLDTVLGLGDDTL--LWP 289
>UniRef50_Q9UT36 Cluster: Hydroxyacylglutathione hydrolase; n=10;
Ascomycota|Rep: Hydroxyacylglutathione hydrolase -
Schizosaccharomyces pombe (Fission yeast)
Length = 256
Score = 59.3 bits (137), Expect = 1e-07
Identities = 53/174 (30%), Positives = 81/174 (46%), Gaps = 9/174 (5%)
Frame = +3
Query: 291 DNYMYLIVDKATKEAAIVDPVEPKTVLKAVEE----QGVNLXXXXXXXXXXXXAGGNEDL 458
+NY YL+ TK AIVDP EP++V+ ++E + ++L AGGNED+
Sbjct: 16 NNYAYLLTCDKTKITAIVDPAEPESVIPVIKEKTAKKEIDLQYILTTHHHYDHAGGNEDI 75
Query: 459 IKERPGLIVYGGDDRIG----PSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*LLQ 626
+ P L VYGG + G P K++ + ++ V +++ H + YV S
Sbjct: 76 LSYFPSLKVYGGKNASGVTYTPKDKEIFKVGEVQ-VEALHTP-CHTQDSICYYVSS--PS 131
Query: 627 KKVTIQLSSPGDTLFLGGCGQVL-*RARQIKCTKH*QF*AAA*PH*MFCGHEYT 785
K+ GDTLF GCG+ A+Q+ + A + GHEYT
Sbjct: 132 KRAVF----TGDTLFTSGCGRFFEGDAKQMDYALNHVLAALPDDTVTYPGHEYT 181
Score = 51.6 bits (118), Expect = 2e-05
Identities = 30/78 (38%), Positives = 41/78 (52%)
Frame = +2
Query: 542 FKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGSLKGTADQMY 721
FK+G + V+ L TPCHT ICY+V++P + VFTG TL +G A QM
Sbjct: 103 FKVGEVQVEALHTPCHTQDSICYYVSSPSK---RAVFTGD-TLFTSGCGRFFEGDAKQMD 158
Query: 722 KALTILSSCLTTLNVLWP 775
AL + + L V +P
Sbjct: 159 YALNHVLAALPDDTVTYP 176
>UniRef50_A6GS22 Cluster: Metallo-beta-lactamase family protein;
n=1; Limnobacter sp. MED105|Rep: Metallo-beta-lactamase
family protein - Limnobacter sp. MED105
Length = 257
Score = 58.0 bits (134), Expect = 3e-07
Identities = 59/186 (31%), Positives = 82/186 (44%), Gaps = 8/186 (4%)
Frame = +3
Query: 252 VKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXX 431
V N V +PA QDNY++ IV + +K +VDP K+V + ++ G +L
Sbjct: 9 VSNWSVYGIPAFQDNYLWAIVHEPSKACMVVDPGCSKSVQEFLDSHGYHLSGILVTHHHM 68
Query: 432 XXAGGNEDLI-KERPGLIVYG-GDDRIGPSQKKL---STIQSLKSVT*MYSVFLHPVIQL 596
GG + L+ K L VYG RI + + T+ V + V H V L
Sbjct: 69 DHVGGIDALLSKAGKDLPVYGPASGRIAQINRPVREGDTVDVHCLVAQVLEVPGHTVDHL 128
Query: 597 GIYVIS*LLQKKVTIQLSSPGDTLFLGGCGQVL-*RARQI--KCTKH*QF*AAA*PH*MF 767
YVI PGDTLF GGCG++ A+Q+ K QF A ++
Sbjct: 129 A-YVIELKDTMNSEETWMFPGDTLFSGGCGRLFEGSAQQMFESLQKLNQFPANT---RVY 184
Query: 768 CGHEYT 785
C HEYT
Sbjct: 185 CAHEYT 190
>UniRef50_O94250 Cluster: Hydroxyacylglutathione hydrolase; n=1;
Schizosaccharomyces pombe|Rep: Hydroxyacylglutathione
hydrolase - Schizosaccharomyces pombe (Fission yeast)
Length = 256
Score = 56.0 bits (129), Expect = 1e-06
Identities = 30/80 (37%), Positives = 46/80 (57%), Gaps = 4/80 (5%)
Frame = +3
Query: 288 QDNYMYLIVDKATKEAAIVDPVEPKTVL----KAVEEQGVNLXXXXXXXXXXXXAGGNED 455
QDNY YL++ + T++AAIVDP E V+ K ++ + ++L +GGN +
Sbjct: 15 QDNYAYLLLCEETRQAAIVDPAEVNVVMPILKKKLKNKEIDLQAILTTHHHADHSGGNLN 74
Query: 456 LIKERPGLIVYGGDDRIGPS 515
L KE P + +YGG D+ G S
Sbjct: 75 LKKEFPHVTIYGGSDQNGVS 94
Score = 52.8 bits (121), Expect = 1e-05
Identities = 28/77 (36%), Positives = 41/77 (53%)
Frame = +2
Query: 545 KIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGSLKGTADQMYK 724
+IGN+ ++ L TPCHT IC++ N+ VFTG TL +GTA +M+
Sbjct: 104 RIGNVQIEALHTPCHTRDSICFYA---HSSNEHAVFTGD-TLFNAGCGRFFEGTAAEMHI 159
Query: 725 ALTILSSCLTTLNVLWP 775
AL + S L V++P
Sbjct: 160 ALNAVLSSLPNNTVIYP 176
>UniRef50_UPI0000E4A799 Cluster: PREDICTED: similar to CG4365-PC,
partial; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to CG4365-PC, partial -
Strongylocentrotus purpuratus
Length = 68
Score = 54.8 bits (126), Expect = 2e-06
Identities = 23/35 (65%), Positives = 30/35 (85%)
Frame = +3
Query: 258 NMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPK 362
+M + +L AL+DNYMYL+ D+ATKEAAIVDPV P+
Sbjct: 33 DMKITLLSALEDNYMYLLTDEATKEAAIVDPVNPE 67
>UniRef50_Q940L0 Cluster: Glyoxalase II; n=9; Magnoliophyta|Rep:
Glyoxalase II - Oryza sativa (Rice)
Length = 336
Score = 54.8 bits (126), Expect = 2e-06
Identities = 52/187 (27%), Positives = 82/187 (43%), Gaps = 3/187 (1%)
Frame = +3
Query: 258 NMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXX 437
++ ++++P LQDNY Y++ D T +VDP E ++ A+E++ NL
Sbjct: 82 SLQIELVPCLQDNYAYILHDVDTGTVGVVDPSEATPIINALEKRNQNLTYILNTHHHYDH 141
Query: 438 AGGNEDLIKERPGLIVYGG---DDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYV 608
GGN +L K + G V G DRI LS + T M++ V++ +
Sbjct: 142 TGGNLEL-KAKYGAKVIGSAKDRDRIPGIDITLS-----EGDTWMFAGHQVLVMETPGHT 195
Query: 609 IS*LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTL 788
+ GDTLF CG++ Q + + A ++CGHEYTL
Sbjct: 196 SGHVCYHFPGSGAIFTGDTLFSLSCGKLFEGTPQQMYSSLQKIIALPDETRVYCGHEYTL 255
Query: 789 AGIXKFA 809
+ KFA
Sbjct: 256 SN-SKFA 261
Score = 35.1 bits (77), Expect = 2.1
Identities = 21/51 (41%), Positives = 26/51 (50%)
Frame = +2
Query: 578 TPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGSLKGTADQMYKAL 730
TP HT+GH+CY P G +FTG TL +GT QMY +L
Sbjct: 191 TPGHTSGHVCYHF--PGSG---AIFTGD-TLFSLSCGKLFEGTPQQMYSSL 235
>UniRef50_Q4QGS1 Cluster: Hydroxyacylglutathione hydrolase,
putative; n=8; Trypanosomatidae|Rep:
Hydroxyacylglutathione hydrolase, putative - Leishmania
major
Length = 295
Score = 54.0 bits (124), Expect = 4e-06
Identities = 25/74 (33%), Positives = 38/74 (51%)
Frame = +2
Query: 509 ALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWA 688
A+TK V + ++GNL+V+ + PCHT GH+ Y V P+ ND V G T+
Sbjct: 113 AVTKPVREGDRVQVGNLSVEVIDAPCHTRGHVLYKVQHPQHPNDGVALFTGDTMFIAGIG 172
Query: 689 GSLKGTADQMYKAL 730
+G M +A+
Sbjct: 173 AFFEGDEKDMCRAM 186
Score = 33.1 bits (72), Expect = 8.6
Identities = 17/41 (41%), Positives = 24/41 (58%), Gaps = 1/41 (2%)
Frame = +3
Query: 267 VKILPALQDNYMYLIVDKATKEAAIVD-PVEPKTVLKAVEE 386
V ++P L+DN+ YLI D T A VD + K +L +EE
Sbjct: 15 VTVVPTLKDNFSYLINDHTTHTLAAVDVNADYKPILTYIEE 55
>UniRef50_Q1K398 Cluster: Hydroxyacylglutathione hydrolase; n=1;
Desulfuromonas acetoxidans DSM 684|Rep:
Hydroxyacylglutathione hydrolase - Desulfuromonas
acetoxidans DSM 684
Length = 249
Score = 53.2 bits (122), Expect = 8e-06
Identities = 53/175 (30%), Positives = 73/175 (41%)
Frame = +3
Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
+++ +L A DNY Y+I D T A +DP E + VL +E+ G +L
Sbjct: 2 VEITLLQAHDDNYAYMISDGDTTIA--IDPGEAEPVLDYLEKHGRSLSLILNTHMHQDHC 59
Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*L 620
GGN L K G + GGD+RI + L L + V P G L
Sbjct: 60 GGNLTL-KRLTGCHIAGGDERIVGVDRLLQEDSVLPGLPWPLQVMHTPGHTRGDCCYY-L 117
Query: 621 LQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYT 785
Q + GDTLF GGCG+V + + A ++CGHEYT
Sbjct: 118 PQCEALF----CGDTLFSGGCGRVFEGTMEQLYHSLQKITALPETTRLYCGHEYT 168
>UniRef50_A0YBD1 Cluster: Metallo-beta-lactamase superfamily
protein; n=7; Bacteria|Rep: Metallo-beta-lactamase
superfamily protein - marine gamma proteobacterium
HTCC2143
Length = 260
Score = 53.2 bits (122), Expect = 8e-06
Identities = 53/180 (29%), Positives = 80/180 (44%), Gaps = 3/180 (1%)
Frame = +3
Query: 267 VKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGG 446
++ +PA DNY++ I D + +AA+VDP E V +A+ Q + L GG
Sbjct: 4 IEPIPAFNDNYIWCIYDDDSGKAAVVDPGEAGPVEEALLAQQLQLETILITHHHFDHTGG 63
Query: 447 NEDLIKERPGLIVYG-GDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*LL 623
E L K R + VYG + +I +L S+ +++ P L I+
Sbjct: 64 IEALTKHR-DIPVYGPKNHQIASITHRLDEQSSMSLFGLDFTILEVPGHTLD--HIALYC 120
Query: 624 QKKVTIQ-LSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*P-H*MFCGHEYTLAGI 797
+ T Q + GDTLF GGCG++ Q AA P ++C HEYTL +
Sbjct: 121 EDTGTGQPVLFCGDTLFAGGCGRIF-EGNPTMMLNSLQKLAALPPTTEIYCAHEYTLGNL 179
>UniRef50_A5IBE7 Cluster: Hydroxyacylglutathione hydrolase GloB;
n=4; Legionella pneumophila|Rep: Hydroxyacylglutathione
hydrolase GloB - Legionella pneumophila (strain Corby)
Length = 254
Score = 52.0 bits (119), Expect = 2e-05
Identities = 49/184 (26%), Positives = 75/184 (40%), Gaps = 1/184 (0%)
Frame = +3
Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
M + + A DNY++ +DK VDP E +++ + + L
Sbjct: 1 MTILPISAFSDNYIWAFIDKIAGVLDCVDPGEAAPIIRFAQSNQLTLRTILLTHHHYDHI 60
Query: 441 GGNEDLIKERPGLIVYGG-DDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS* 617
GG + LIK+ P VYG D+RI + QS++ + + + +P ++
Sbjct: 61 GGVDSLIKQWPSCKVYGPIDERINNVTHPIKQGQSVQVGSLHFHILFNPG-HTSTHISYY 119
Query: 618 LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLAGI 797
QK GDTLF GCG+V + F +FC HEYTL +
Sbjct: 120 EPQKGWLF----CGDTLFSAGCGRVFDGTIEELHESLLLFKKLPRNTKVFCAHEYTLQNL 175
Query: 798 XKFA 809
KFA
Sbjct: 176 -KFA 178
Score = 33.5 bits (73), Expect = 6.5
Identities = 20/75 (26%), Positives = 39/75 (52%)
Frame = +2
Query: 512 LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAG 691
+T ++ ++G+L+ LF P HT+ HI Y+ P++G +F G TL
Sbjct: 86 VTHPIKQGQSVQVGSLHFHILFNPGHTSTHISYY--EPQKG---WLFCGD-TLFSAGCGR 139
Query: 692 SLKGTADQMYKALTI 736
GT ++++++L +
Sbjct: 140 VFDGTIEELHESLLL 154
>UniRef50_Q6F9P0 Cluster: Putative hydroxyacylglutathione hydrolase;
n=1; Acinetobacter sp. ADP1|Rep: Putative
hydroxyacylglutathione hydrolase - Acinetobacter sp.
(strain ADP1)
Length = 244
Score = 51.6 bits (118), Expect = 2e-05
Identities = 31/85 (36%), Positives = 46/85 (54%)
Frame = +2
Query: 512 LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAG 691
+T ++H FK +LNV+ L TP HT GH+ YF+ E G+ +F G TL
Sbjct: 92 ITHPLQHENHFKFNHLNVEVLATPGHTLGHVVYFI--EETGS---LFCGD-TLFAMGCGR 145
Query: 692 SLKGTADQMYKALTILSSCLTTLNV 766
+G+ +QMY +L L++ TT V
Sbjct: 146 VFEGSFEQMYHSLNRLAALPTTTKV 170
Score = 39.1 bits (87), Expect = 0.13
Identities = 44/169 (26%), Positives = 69/169 (40%), Gaps = 3/169 (1%)
Frame = +3
Query: 294 NYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERP 473
NY++++ D T+E +VDP E V + E+ V + GG DLI +
Sbjct: 17 NYIWILKDSHTQEIIVVDPTESSLVQQYCEKHQVKIAQIWLTHWHKDHIGGVPDLI-DGS 75
Query: 474 GLIVYGGDDRIGPSQKKLSTIQ---SLKSVT*MYSVFLHPVIQLGIYVIS*LLQKKVTIQ 644
+ VYG + + +Q K V P LG V +++ ++
Sbjct: 76 HIPVYGPREELSKIPLITHPLQHENHFKFNHLNVEVLATPGHTLGHVVY--FIEETGSLF 133
Query: 645 LSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLA 791
GDTLF GCG+V + + + A ++C HEYTLA
Sbjct: 134 C---GDTLFAMGCGRVFEGSFEQMYHSLNRLAALPTTTKVYCTHEYTLA 179
>UniRef50_A4VLR2 Cluster: Hydroxyacylglutathione hydrolase; n=4;
Proteobacteria|Rep: Hydroxyacylglutathione hydrolase -
Pseudomonas stutzeri (strain A1501)
Length = 292
Score = 51.2 bits (117), Expect = 3e-05
Identities = 54/193 (27%), Positives = 82/193 (42%), Gaps = 2/193 (1%)
Frame = +3
Query: 237 PRGPPVKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVE-EQGVNLXXXX 413
P G P ++ LPA DNY++L+ D A + VDP + VL + G L
Sbjct: 28 PLGDP-SMFKIEALPAFTDNYIWLLQDDAARRCVAVDPGDAAPVLNWLSAHPGWQLSDIL 86
Query: 414 XXXXXXXXAGGNEDLIKERPGLIVYG-GDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVI 590
GG E L K + G VYG ++I + LS Q ++ + + P
Sbjct: 87 VTHHHHDHVGGVERL-KAQTGARVYGPAAEKIPARDEALSDGQRIEVLGKRLQIIAVPGH 145
Query: 591 QLGIYVIS*LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFC 770
LG ++ LS GDTLF GCG++ + + +A ++C
Sbjct: 146 TLG-HIAYFHADPDQPWLLS--GDTLFAAGCGRLFEGTPEQMFESLTRLASAPDHTLVYC 202
Query: 771 GHEYTLAGIXKFA 809
HEYTL+ + +FA
Sbjct: 203 THEYTLSNL-RFA 214
>UniRef50_A4XU09 Cluster: Hydroxyacylglutathione hydrolase; n=2;
Pseudomonadales|Rep: Hydroxyacylglutathione hydrolase -
Pseudomonas mendocina ymp
Length = 257
Score = 50.8 bits (116), Expect = 4e-05
Identities = 47/184 (25%), Positives = 74/184 (40%), Gaps = 1/184 (0%)
Frame = +3
Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQG-VNLXXXXXXXXXXXX 437
+ + LPA DNY++L+ D ++ A+VDP + VL +E G L
Sbjct: 2 IQIDALPAFNDNYIWLLQDPISRRCAVVDPGDAAPVLAWLEAHGDWTLSDILITHHHFDH 61
Query: 438 AGGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS* 617
GG E L K + ++I L ++ + + + P LG
Sbjct: 62 VGGVEQLKKATGARVAGPAAEKIPARDVDLGDNDLIEVLGLRFQIMAVPGHTLGH----- 116
Query: 618 LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLAGI 797
+ L GDTLF GGCG++ Q + A ++C HEYTL+ +
Sbjct: 117 IAYYHAEQNLLLCGDTLFAGGCGRLFEGTPQQMHQSLSRLAALPGATRVYCTHEYTLSNL 176
Query: 798 XKFA 809
+FA
Sbjct: 177 -RFA 179
>UniRef50_Q5AXZ0 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 659
Score = 50.4 bits (115), Expect = 5e-05
Identities = 37/116 (31%), Positives = 56/116 (48%), Gaps = 15/116 (12%)
Frame = +2
Query: 506 RALTKKVEHNTKFKIGN-LNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRM 682
+++TK H FKIG+ ++V L TPCHT ICYF+ ++G VFTG + M
Sbjct: 468 QSVTKTPAHGEVFKIGDRISVTALHTPCHTQDSICYFM---QDGEQKAVFTGDTLFIGGM 524
Query: 683 --WAGS-----------LKGTADQMYKALTILSSCLTTLNVLWP*VHFGR-NXKIC 808
W + +GTA +M+KAL + L ++P + + N K C
Sbjct: 525 TEWINAESSAAAGCGRFFEGTAPEMHKALNETLASLPEDTKVYPGHEYTKGNVKFC 580
Score = 44.8 bits (101), Expect = 0.003
Identities = 40/137 (29%), Positives = 64/137 (46%), Gaps = 7/137 (5%)
Frame = +3
Query: 291 DNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQ----GVNLXXXXXXXXXXXXAGGNEDL 458
+NY YL+ D+ TK++ I+DP P V+ +E Q +NL AGGN ++
Sbjct: 394 NNYAYLVTDEPTKQSVIIDPANPPEVVPELEAQTKAGKINLTAIVNTHHHWDHAGGNNEV 453
Query: 459 IKERPGLIVYGGDDRI---GPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*LLQK 629
+K ++ G D + P+ ++ I SVT +++ H + Y + QK
Sbjct: 454 LKTFKVPVIGGKDCQSVTKTPAHGEVFKIGDRISVTALHTP-CHTQDSI-CYFMQDGEQK 511
Query: 630 KVTIQLSSPGDTLFLGG 680
V GDTLF+GG
Sbjct: 512 AV-----FTGDTLFIGG 523
>UniRef50_A1U0V1 Cluster: Hydroxyacylglutathione hydrolase; n=3;
Marinobacter|Rep: Hydroxyacylglutathione hydrolase -
Marinobacter aquaeolei (strain ATCC 700491 / DSM 11845 /
VT8)(Marinobacter hydrocarbonoclasticus (strain DSM
11845))
Length = 263
Score = 50.0 bits (114), Expect = 7e-05
Identities = 45/187 (24%), Positives = 81/187 (43%), Gaps = 4/187 (2%)
Frame = +3
Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
M + +PA DNY++ + + + + IVDP + K VL + + G +
Sbjct: 1 MRIHPVPAFSDNYIWCLTNLESGKTLIVDPGQAKPVLDYLSDSGFSADTILITHHHPDHT 60
Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*L 620
GG ++L ++ P L + G D P + +T+ + V ++ V+ + + + +
Sbjct: 61 GGVKELQQQYPDLRIVGPTD--SPFKGATNTVHAGDEV--VWEGITFNVLAVPGHTLDHI 116
Query: 621 LQKKVTIQLSSP----GDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTL 788
T P GDTLF+ GCG++ + T ++C HEYTL
Sbjct: 117 AYYSDTQVNDKPVLFCGDTLFVCGCGRLFEGTPEQMHTSLQTLRDLPDNTAVYCAHEYTL 176
Query: 789 AGIXKFA 809
A + +FA
Sbjct: 177 ANL-RFA 182
>UniRef50_Q4PH24 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 268
Score = 50.0 bits (114), Expect = 7e-05
Identities = 41/183 (22%), Positives = 71/183 (38%), Gaps = 4/183 (2%)
Frame = +3
Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGV---NLXXXXXXXXXX 431
M + + +DNY Y++ A VD + + V A E+ G+ N+
Sbjct: 1 MKIHPVAVREDNYAYILQSSVDGRAVFVDVFDVEAVSGAAEKLGIPNENVVGLLTTHHHF 60
Query: 432 XXAGGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSV-FLHPVIQLGIYV 608
+GGNE PG +YGG D+I K + + + S+ + ++
Sbjct: 61 DHSGGNEAFAHAYPGRPIYGGSDKIPALTKLVHDADRISELLGGVSIECVATPCHTQDHI 120
Query: 609 IS*LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTL 788
+ GDTLF+ GCG+ Q + + + ++CGHEYT
Sbjct: 121 CYHVTDTTTAQSGVFTGDTLFISGCGRFFEGHPQQMLSAMDRLSSLPDHTLVYCGHEYTK 180
Query: 789 AGI 797
+ +
Sbjct: 181 SNV 183
Score = 49.6 bits (113), Expect = 9e-05
Identities = 32/81 (39%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +2
Query: 509 ALTKKVEHNTKFK--IGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRM 682
ALTK V + +G ++++C+ TPCHT HICY VT S VFTG TL
Sbjct: 87 ALTKLVHDADRISELLGGVSIECVATPCHTQDHICYHVTDTTTA-QSGVFTGD-TLFISG 144
Query: 683 WAGSLKGTADQMYKALTILSS 745
+G QM A+ LSS
Sbjct: 145 CGRFFEGHPQQMLSAMDRLSS 165
>UniRef50_A5WFB5 Cluster: Hydroxyacylglutathione hydrolase; n=3;
Psychrobacter|Rep: Hydroxyacylglutathione hydrolase -
Psychrobacter sp. PRwf-1
Length = 259
Score = 49.6 bits (113), Expect = 9e-05
Identities = 39/142 (27%), Positives = 67/142 (47%), Gaps = 3/142 (2%)
Frame = +3
Query: 276 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 455
+PA DNY++ +V+ K+A ++DP + + V +E+ G+ L GG +
Sbjct: 8 IPAFTDNYIWALVNDTNKQAIVIDPGQAQPVADYLEQYGLELTAIWITHHHHDHVGGVAE 67
Query: 456 LIKERPGL-IVYGGDDRIGPSQ--KKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*LLQ 626
L + P +V + + P Q K+ S++ + +++V H L YV+
Sbjct: 68 LRELYPMTHVVASAEHGVKPDQVVKEGSSVSAWGYTAQVWAVPGHTQSHLA-YVLDKEGH 126
Query: 627 KKVTIQLSSPGDTLFLGGCGQV 692
K+V GDTLF GCG+V
Sbjct: 127 KQVFC-----GDTLFSAGCGRV 143
>UniRef50_UPI0000E23FD0 Cluster: PREDICTED: hydroxyacylglutathione
hydrolase-like isoform 2; n=1; Pan troglodytes|Rep:
PREDICTED: hydroxyacylglutathione hydrolase-like isoform
2 - Pan troglodytes
Length = 285
Score = 49.2 bits (112), Expect = 1e-04
Identities = 21/44 (47%), Positives = 29/44 (65%)
Frame = +3
Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQG 392
M VK++P L+DNYMYL++++ T+EA VD PK V QG
Sbjct: 1 MKVKVIPVLEDNYMYLVIEELTREAVAVDVAVPKRVRAGRGPQG 44
Score = 44.0 bits (99), Expect = 0.005
Identities = 24/63 (38%), Positives = 38/63 (60%), Gaps = 1/63 (1%)
Frame = +2
Query: 545 KIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGS-LKGTADQMY 721
+ G ++V+CL TP HT GH+ YF+ + + +F+G L GS L+G+A QMY
Sbjct: 91 QFGAIHVRCLLTPGHTGGHMSYFLWEDDCPDPPALFSG--DALSVAGCGSCLEGSAQQMY 148
Query: 722 KAL 730
++L
Sbjct: 149 QSL 151
>UniRef50_Q2BJ10 Cluster: Metallo-beta-lactamase superfamily
protein; n=1; Neptuniibacter caesariensis|Rep:
Metallo-beta-lactamase superfamily protein -
Neptuniibacter caesariensis
Length = 257
Score = 49.2 bits (112), Expect = 1e-04
Identities = 49/175 (28%), Positives = 76/175 (43%), Gaps = 1/175 (0%)
Frame = +3
Query: 276 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 455
+PA DNY+++I + A+VDP + VL +EE + L GG E
Sbjct: 7 IPAFSDNYIWVIASPDSNMVAVVDPGDEAPVLAYLEENNLQLTAILITHHHNDHTGGVEA 66
Query: 456 LIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*M-YSVFLHPVIQLGIYVIS*LLQKK 632
L K+R VYG + P Q + S+ M SV + + + IS ++
Sbjct: 67 L-KDRFKTPVYGPAN--SPFQGITHPLNDGDSIQLMGASVAIKAIPGHTLDHIS-YYSER 122
Query: 633 VTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLAGI 797
QL GDTLFL GCG++ + F + ++C HEY++A +
Sbjct: 123 HKPQLFC-GDTLFLAGCGRLFEGTAKQMLNAMNYFASLPDDTEVYCTHEYSMANL 176
>UniRef50_O24495 Cluster: Hydroxyacylglutathione hydrolase 1,
mitochondrial precursor; n=12; core eudicotyledons|Rep:
Hydroxyacylglutathione hydrolase 1, mitochondrial
precursor - Arabidopsis thaliana (Mouse-ear cress)
Length = 331
Score = 49.2 bits (112), Expect = 1e-04
Identities = 26/78 (33%), Positives = 41/78 (52%)
Frame = +3
Query: 258 NMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXX 437
++ ++++P +DNY YL+ D+ T +VDP E V++A+ + NL
Sbjct: 77 SLKIELVPCSKDNYAYLLHDEDTGTVGVVDPSEAAPVIEALSRKNWNLTYILNTHHHDDH 136
Query: 438 AGGNEDLIKERPGLIVYG 491
GGN +L KER G V G
Sbjct: 137 IGGNAEL-KERYGAKVIG 153
>UniRef50_P0AC85 Cluster: Probable hydroxyacylglutathione hydrolase;
n=40; Gammaproteobacteria|Rep: Probable
hydroxyacylglutathione hydrolase - Escherichia coli
O157:H7
Length = 251
Score = 48.8 bits (111), Expect = 2e-04
Identities = 47/183 (25%), Positives = 78/183 (42%)
Frame = +3
Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
M++ +PA DNY++++ D+A + IVDP + + VL A+
Sbjct: 1 MNLNSIPAFDDNYIWVLNDEAGR-CLIVDPGDAEPVLNAIAANNWQPEAIFLTHHHHDHV 59
Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*L 620
GG ++L+++ P ++VYG + +Q K +T T VI + + +
Sbjct: 60 GGVKELVEKFPQIVVYGPQE----TQDKGTTQVVKDGETAFVLGHEFSVIATPGHTLGHI 115
Query: 621 LQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLAGIX 800
GDTLF GGCG++ + A + C HEYTL+ +
Sbjct: 116 CYFSKPYLFC--GDTLFSGGCGRLFEGTASQMYQSLKKLSALPDDTLVCCAHEYTLSNM- 172
Query: 801 KFA 809
KFA
Sbjct: 173 KFA 175
Score = 43.2 bits (97), Expect = 0.008
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 1/83 (1%)
Frame = +2
Query: 500 QDRALTKKVEHN-TKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLR 676
QD+ T+ V+ T F +G+ + TP HT GHICYF + P +F+GG L
Sbjct: 81 QDKGTTQVVKDGETAFVLGH-EFSVIATPGHTLGHICYF-SKPYLFCGDTLFSGGCGRL- 137
Query: 677 RMWAGSLKGTADQMYKALTILSS 745
+GTA QMY++L LS+
Sbjct: 138 ------FEGTASQMYQSLKKLSA 154
>UniRef50_UPI0000DAE586 Cluster: hypothetical protein
Rgryl_01000658; n=1; Rickettsiella grylli|Rep:
hypothetical protein Rgryl_01000658 - Rickettsiella
grylli
Length = 257
Score = 48.4 bits (110), Expect = 2e-04
Identities = 44/183 (24%), Positives = 77/183 (42%), Gaps = 4/183 (2%)
Frame = +3
Query: 261 MDVKILP--ALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXX 434
M +++LP A +DNY++ ++++ TK IVDP E K VL +++ + L
Sbjct: 1 MTIQLLPILAFKDNYIWCLINEETKHCLIVDPGEAKPVLAQLKQLNLTLDALLITHHHWD 60
Query: 435 XAGGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS 614
G ++ P + GPS++K+ + + T + P ++ + +
Sbjct: 61 HTNGIRSILNHYPVPV-------FGPSKEKIVGVTHPVNETDKIELTHWPSFEI-LAIPG 112
Query: 615 *LLQKKVTI--QLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTL 788
L L GDTLF GCG++ + ++CGHEYTL
Sbjct: 113 HTLGHIAYYGNHLLFCGDTLFTAGCGRLFEGTPDQMLNSLEKLAQLPDETQIYCGHEYTL 172
Query: 789 AGI 797
A +
Sbjct: 173 ANL 175
>UniRef50_Q01BW2 Cluster: Glyoxylase; n=2; Ostreococcus|Rep:
Glyoxylase - Ostreococcus tauri
Length = 512
Score = 48.0 bits (109), Expect = 3e-04
Identities = 21/58 (36%), Positives = 29/58 (50%)
Frame = +3
Query: 276 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGN 449
+P + DNY YL+VD T+EA +DP +P+ + A G L AGGN
Sbjct: 149 IPFMNDNYSYLVVDADTREACAIDPADPERAVDAARRCGAKLTTVLTTHKHHDHAGGN 206
>UniRef50_Q0F0R2 Cluster: Hydroxyacylglutathione hydrolase; n=1;
Mariprofundus ferrooxydans PV-1|Rep:
Hydroxyacylglutathione hydrolase - Mariprofundus
ferrooxydans PV-1
Length = 262
Score = 47.6 bits (108), Expect = 4e-04
Identities = 47/181 (25%), Positives = 75/181 (41%), Gaps = 1/181 (0%)
Frame = +3
Query: 258 NMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXX 437
N V LP L+DNY+YLI A+ ++DP E +V +A E G L
Sbjct: 8 NFTVHQLPVLKDNYIYLIEAHASSALIVIDPAEAVSVRRACRELGKPLTHIFNTHHHWDH 67
Query: 438 AGGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS* 617
GN+ L K+ +++ D L ++ + ++ + V I+
Sbjct: 68 TDGNQSLKKDFGAVVIGAAHDAERIPGINLKVSEASPPLVDGLNIRVLDVAGHTRGHIAY 127
Query: 618 LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH-*MFCGHEYTLAG 794
LL + GDTLF GCG++ + + Q A + ++C HEYTLA
Sbjct: 128 LLDDALFC-----GDTLFGAGCGRLF-EGTPAQMWQSLQKIAQLDGNTRIYCAHEYTLAN 181
Query: 795 I 797
+
Sbjct: 182 L 182
>UniRef50_Q12320 Cluster: Hydroxyacylglutathione hydrolase,
mitochondrial precursor; n=10; Saccharomycetales|Rep:
Hydroxyacylglutathione hydrolase, mitochondrial
precursor - Saccharomyces cerevisiae (Baker's yeast)
Length = 285
Score = 47.6 bits (108), Expect = 4e-04
Identities = 26/73 (35%), Positives = 39/73 (53%)
Frame = +2
Query: 512 LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAG 691
+T+ ++ ++ +GNL V C+ TPCHT ICY++ E G + +FTG TL
Sbjct: 106 VTEVPDNLQQYHLGNLRVTCIRTPCHTKDSICYYIKDLETG-EQCIFTGD-TLFIAGCGR 163
Query: 692 SLKGTADQMYKAL 730
+GT M AL
Sbjct: 164 FFEGTGRDMDMAL 176
>UniRef50_A5DYF9 Cluster: Hydroxyacylglutathione hydrolase; n=2;
Saccharomycetaceae|Rep: Hydroxyacylglutathione hydrolase
- Lodderomyces elongisporus (Yeast) (Saccharomyces
elongisporus)
Length = 282
Score = 47.2 bits (107), Expect = 5e-04
Identities = 38/139 (27%), Positives = 63/139 (45%), Gaps = 6/139 (4%)
Frame = +3
Query: 291 DNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQ--GVNLXXXXXXXXXXXXAGGNEDLIK 464
DNY YL+VD +K A ++DP P V + ++E+ L + GN++ +
Sbjct: 41 DNYAYLLVDDRSKNAWLIDPAVPLEVNEFIKEKKPKYELKAIVNTHHHYDHSDGNKEFHR 100
Query: 465 ERPGLIVYGGDD----RIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*LLQKK 632
+ P L + G D PS +++ + SVT +++ H + YV +K
Sbjct: 101 KYPDLPIIAGKDSPLVTYTPSHEEVIDLGDDLSVTALHTP-CHTQDSICYYVKDAKTGEK 159
Query: 633 VTIQLSSPGDTLFLGGCGQ 689
GDTLF+ GCG+
Sbjct: 160 AVF----TGDTLFISGCGR 174
>UniRef50_Q89XT5 Cluster: Glyoxalase II; n=16;
Alphaproteobacteria|Rep: Glyoxalase II - Bradyrhizobium
japonicum
Length = 255
Score = 46.8 bits (106), Expect = 7e-04
Identities = 46/182 (25%), Positives = 72/182 (39%)
Frame = +3
Query: 264 DVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAG 443
+++ L DN+ YLI D TK A +D E +LKA+E +G L G
Sbjct: 4 EIRTFSCLNDNFGYLIHDVETKATASIDAPEAGPILKALEREGWQLTDILITHHHGDHVG 63
Query: 444 GNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*LL 623
G +L K + V D+ + + V L V++ + + +
Sbjct: 64 GVAEL-KHKYNCRVVAPHDKTTAIANVDLRVANADVV--KVGNLLARVVETPGHTLDHIS 120
Query: 624 QKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLAGIXK 803
T + DTLF GCG+V + + A ++CGHEYT + + K
Sbjct: 121 YVFDTEKTVFAADTLFSIGCGRVFEGTYPMMWDSLLKLRALPDDFKLYCGHEYTASNV-K 179
Query: 804 FA 809
FA
Sbjct: 180 FA 181
>UniRef50_Q4UGN4 Cluster: Hydroxyacylglutathione hydrolase,
putative; n=2; Theileria|Rep: Hydroxyacylglutathione
hydrolase, putative - Theileria annulata
Length = 362
Score = 46.8 bits (106), Expect = 7e-04
Identities = 24/78 (30%), Positives = 35/78 (44%)
Frame = +2
Query: 512 LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAG 691
+T V+H GNL ++CL CHT GHI Y+V P + + G TL
Sbjct: 195 VTLPVKHEQTLTFGNLVIKCLKASCHTLGHIMYYVYHPSNDHQQPLLFSGDTLFISGCGR 254
Query: 692 SLKGTADQMYKALTILSS 745
+G A M + + + S
Sbjct: 255 FFEGDARSMMEIVETVKS 272
Score = 41.5 bits (93), Expect = 0.025
Identities = 19/46 (41%), Positives = 27/46 (58%)
Frame = +3
Query: 264 DVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNL 401
+V I+P LQDNY Y++ D + A VDPVE + V +E + L
Sbjct: 85 EVLIVPVLQDNYSYVLKDPESSNALCVDPVEYEKVYNVCKENDLEL 130
>UniRef50_Q4DNS9 Cluster: Putative uncharacterized protein; n=3;
Trypanosoma cruzi|Rep: Putative uncharacterized protein
- Trypanosoma cruzi
Length = 536
Score = 44.0 bits (99), Expect = 0.005
Identities = 18/32 (56%), Positives = 24/32 (75%)
Frame = +3
Query: 276 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVL 371
+P L DNY YLI+ ATK+ A+VDP +PK V+
Sbjct: 208 VPLLADNYAYLILSFATKKCAVVDPADPKLVM 239
>UniRef50_A6VVZ9 Cluster: Hydroxyacylglutathione hydrolase; n=2;
Marinomonas|Rep: Hydroxyacylglutathione hydrolase -
Marinomonas sp. MWYL1
Length = 257
Score = 43.6 bits (98), Expect = 0.006
Identities = 39/145 (26%), Positives = 61/145 (42%)
Frame = +3
Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
M + LPA DNY+++I DK + VDP + VL E L
Sbjct: 1 MTIFPLPAFNDNYIWIIQDKDSSGIWAVDPGKADVVLNFCHEYQKTLTGILITHHHKDHT 60
Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*L 620
GG +L K+ VYG + + + + +++V P L +
Sbjct: 61 GGVAEL-KQHSNCPVYGPEHLTELVTHPVDDGDRILVFSKVFTVIATPGHTLD--HLCYF 117
Query: 621 LQKKVTIQLSSPGDTLFLGGCGQVL 695
+++ I LS GDTLF GGCG+++
Sbjct: 118 SEQETPILLS--GDTLFKGGCGRIM 140
>UniRef50_A4SXM4 Cluster: Hydroxyacylglutathione hydrolase
precursor; n=44; Bacteria|Rep: Hydroxyacylglutathione
hydrolase precursor - Polynucleobacter sp. QLW-P1DMWA-1
Length = 269
Score = 43.6 bits (98), Expect = 0.006
Identities = 49/186 (26%), Positives = 81/186 (43%), Gaps = 8/186 (4%)
Frame = +3
Query: 276 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 455
+PA DNY++ I + K A +VDP + VL+ +++ G+ L GG
Sbjct: 12 IPAFDDNYIWCIHNG--KSALVVDPGDAVPVLEYLKQSGLRLTGILITHHHADHTGGILA 69
Query: 456 LI----KERPGLIVYG----GDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVI 611
L+ K+ P + G G +I + K+ I S + +Y V H + + +
Sbjct: 70 LLDALGKDIPVIGPAGSNIPGRTQIAKADDKIE-ITSPRISLQVYEVPGHTLSHIAYFA- 127
Query: 612 S*LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLA 791
+Q V + GDTLF GCG++ +F + ++C HEYTL+
Sbjct: 128 --NMQANVVEPMLFCGDTLFASGCGRLFEGTPTQMTQSLAKFASLPKNTLVYCTHEYTLS 185
Query: 792 GIXKFA 809
I +FA
Sbjct: 186 NI-RFA 190
>UniRef50_Q7VD23 Cluster: Metallo-beta-lactamase superfamily
hydrolase; n=7; Prochlorococcus marinus|Rep:
Metallo-beta-lactamase superfamily hydrolase -
Prochlorococcus marinus
Length = 253
Score = 43.2 bits (97), Expect = 0.008
Identities = 24/78 (30%), Positives = 41/78 (52%), Gaps = 1/78 (1%)
Frame = +2
Query: 515 TKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGN-DSVVFTGGYTLLRRMWAG 691
TK V N + I ++ + P HT+ HIC+F+ +E D V+F G TL
Sbjct: 94 TKSVVDNEELDILGQKIKVIEVPGHTSNHICFFLQGSKESKIDPVLFCGD-TLFGAGCGR 152
Query: 692 SLKGTADQMYKALTILSS 745
+GT +QM+ +L+ +++
Sbjct: 153 LFEGTPEQMFNSLSRINN 170
Score = 37.1 bits (82), Expect = 0.53
Identities = 42/179 (23%), Positives = 71/179 (39%), Gaps = 5/179 (2%)
Frame = +3
Query: 276 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 455
+P L DN +++ V + K+A +VDP + V+ ++ G++L GG ++
Sbjct: 13 IPVLMDNIIWIWVKE--KQAIVVDPAISEPVINLLKGNGLSLHSVLQTHHHEDHIGGTQE 70
Query: 456 LIKERPGLIVYGGD---DRIGPSQKKLSTIQSLKSVT*MYSVFLHP--VIQLGIYVIS*L 620
LI P V DRI K + + L + V P + +
Sbjct: 71 LINVWPSASVIAAKSDLDRIQFQTKSVVDNEELDILGQKIKVIEVPGHTSNHICFFLQGS 130
Query: 621 LQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLAGI 797
+ K+ L GDTLF GCG++ + + ++C HEYT A +
Sbjct: 131 KESKIDPVLFC-GDTLFGAGCGRLFEGTPEQMFNSLSRINNLPKNTKIYCAHEYTEANL 188
>UniRef50_Q60BX0 Cluster: Metallo-beta-lactamase family protein;
n=9; Proteobacteria|Rep: Metallo-beta-lactamase family
protein - Methylococcus capsulatus
Length = 256
Score = 42.7 bits (96), Expect = 0.011
Identities = 24/77 (31%), Positives = 38/77 (49%)
Frame = +3
Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
+++ +P L+DNY+YL+ + + A VDP VL+A++ +G L
Sbjct: 2 LEILQIPVLEDNYVYLLHEPGSGATAAVDPAVAGPVLEALDARGWRLGHVLNTHHHGDHV 61
Query: 441 GGNEDLIKERPGLIVYG 491
GGN +L K G V G
Sbjct: 62 GGNLEL-KAATGCTVVG 77
Score = 34.3 bits (75), Expect = 3.7
Identities = 18/64 (28%), Positives = 37/64 (57%)
Frame = +2
Query: 539 KFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGSLKGTADQM 718
+F++G+ + + L P HT+GH+ ++ +D+ +F G TL +G+A+QM
Sbjct: 97 EFRLGSASARMLDVPGHTSGHVAFWFE-----DDAALFCGD-TLFALGCGRLFEGSAEQM 150
Query: 719 YKAL 730
+++L
Sbjct: 151 WRSL 154
>UniRef50_A4C5I6 Cluster: Putative hydroxyacylglutathione hydrolase
with metallo- hydrolase/oxidoreductase domain; n=4;
Proteobacteria|Rep: Putative hydroxyacylglutathione
hydrolase with metallo- hydrolase/oxidoreductase domain
- Pseudoalteromonas tunicata D2
Length = 261
Score = 42.7 bits (96), Expect = 0.011
Identities = 32/144 (22%), Positives = 62/144 (43%)
Frame = +3
Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
+ VK + A +DNY++ I++ + +VDP + + V+ + E + L
Sbjct: 4 LQVKPIKAFKDNYIWAIINTENQHCVVVDPGDAEPVIAFISEHQLTLSAILITHHHWDHT 63
Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*L 620
G E L + L VYG + + + ++ +T + + H + G + + +
Sbjct: 64 NGVEKLCSLQASLPVYGPKNSPFAGITEPLSANTVCQLT-DFDLSFHILATPG-HTLDHI 121
Query: 621 LQKKVTIQLSSPGDTLFLGGCGQV 692
+ GDTLF GGCG++
Sbjct: 122 CYYEPQQDWLFCGDTLFSGGCGRL 145
Score = 36.3 bits (80), Expect = 0.93
Identities = 26/79 (32%), Positives = 40/79 (50%), Gaps = 2/79 (2%)
Frame = +2
Query: 512 LTKKVEHNTKFKIGN--LNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMW 685
+T+ + NT ++ + L+ L TP HT HICY+ E +F G TL
Sbjct: 89 ITEPLSANTVCQLTDFDLSFHILATPGHTLDHICYY-----EPQQDWLFCGD-TLFSGGC 142
Query: 686 AGSLKGTADQMYKALTILS 742
+GTADQM++++ LS
Sbjct: 143 GRLFEGTADQMFQSMVKLS 161
>UniRef50_Q1GVB7 Cluster: Hydroxyacylglutathione hydrolase
precursor; n=5; Sphingomonadaceae|Rep:
Hydroxyacylglutathione hydrolase precursor -
Sphingopyxis alaskensis (Sphingomonas alaskensis)
Length = 246
Score = 42.3 bits (95), Expect = 0.014
Identities = 42/181 (23%), Positives = 73/181 (40%), Gaps = 4/181 (2%)
Frame = +3
Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
+++ +P L DNY++L+ + A+ +VDP VL A + +G +
Sbjct: 4 LEIVRIPVLSDNYVWLVHEPASGATMVVDPAVADPVLDAAKARGWAITDIWNTHWHPDHT 63
Query: 441 GGNEDLIKERPGLIVYGGDDRIGPS--QKKLSTIQSL--KSVT*MYSVFLHPVIQLGIYV 608
GGN IKE +GG GP+ +++ T+ L T + V + +
Sbjct: 64 GGNA-AIKE--AAKAWGGCTITGPAAEHERIPTLDVLVKGGDTVRLGDHVADVWDVPAHT 120
Query: 609 IS*LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTL 788
+ GDT+F GCG++ + + A ++C HEYTL
Sbjct: 121 AGHIAYHFADDAAIFVGDTMFAMGCGRLFEGTAEQMFANMQKLRALDDATRVYCAHEYTL 180
Query: 789 A 791
+
Sbjct: 181 S 181
>UniRef50_A1SS88 Cluster: Hydroxyacylglutathione hydrolase; n=2;
Psychromonas|Rep: Hydroxyacylglutathione hydrolase -
Psychromonas ingrahamii (strain 37)
Length = 256
Score = 41.9 bits (94), Expect = 0.019
Identities = 42/147 (28%), Positives = 66/147 (44%), Gaps = 4/147 (2%)
Frame = +3
Query: 264 DVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAG 443
+V + A +DNY++LI D ++ IVDP + VL +E+Q + + G
Sbjct: 3 NVITIKAFEDNYIWLIKDSQSQHCIIVDPGDAAPVLTILEDQKLIVDAILLTHHHYDHIG 62
Query: 444 GNEDLIKERPGLIVYGGDDRIG-PSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*L 620
G + L+ R D++I S+KKL L + + S F + L + +
Sbjct: 63 GVDALLSAR--------DEKISIYSKKKLFDRCRLVNESDTLS-FFDGKLSLQVMEVPGH 113
Query: 621 LQKKVTI---QLSSPGDTLFLGGCGQV 692
V +L GDTLF GGCG+V
Sbjct: 114 TLDHVAFYNDELLFCGDTLFSGGCGRV 140
>UniRef50_Q4Q2K2 Cluster: Putative uncharacterized protein; n=3;
Leishmania|Rep: Putative uncharacterized protein -
Leishmania major
Length = 518
Score = 41.9 bits (94), Expect = 0.019
Identities = 19/47 (40%), Positives = 28/47 (59%)
Frame = +3
Query: 243 GPPVKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVE 383
G ++ + V +P DNY YLIV T + A VDP +P+ VL+ +E
Sbjct: 154 GSVMRGVAVVPIPIFGDNYAYLIVSMQTHKVAAVDPADPEMVLRIME 200
>UniRef50_A1WFG7 Cluster: Hydroxyacylglutathione hydrolase
precursor; n=4; Proteobacteria|Rep:
Hydroxyacylglutathione hydrolase precursor -
Verminephrobacter eiseniae (strain EF01-2)
Length = 258
Score = 40.3 bits (90), Expect = 0.057
Identities = 48/184 (26%), Positives = 75/184 (40%), Gaps = 1/184 (0%)
Frame = +3
Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
M++ LPA DNY++++ D A +VDP + V A+ G+ L
Sbjct: 1 MNLLALPAFADNYLWMLHD--GHRAIVVDPGQAAPVADALRRLGLQLQAILVTHHHADHV 58
Query: 441 GGNEDLIKERPGLIVYG-GDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS* 617
GG E L + G V+G + + +L+ ++ + V P G I+
Sbjct: 59 GGVEAL-RNATGASVHGPARESVPEPLVRLAQGDTVDVLGLRLEVIDVPGHTAG--HIAY 115
Query: 618 LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLAGI 797
+ L GDTLF GGCG++ + A + C HEYTL+ +
Sbjct: 116 YCPQMDGAPLLFCGDTLFSGGCGRLFEGTPAQMLASLDRLAALPGNTLVCCAHEYTLSNL 175
Query: 798 XKFA 809
KFA
Sbjct: 176 -KFA 178
>UniRef50_Q581U6 Cluster: Hydroxyacylglutathione hydrolase,
putative; n=1; Trypanosoma brucei|Rep:
Hydroxyacylglutathione hydrolase, putative - Trypanosoma
brucei
Length = 464
Score = 40.3 bits (90), Expect = 0.057
Identities = 17/36 (47%), Positives = 22/36 (61%)
Frame = +3
Query: 276 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVE 383
+P L DNY Y I+ TK A+VDP +P VL +E
Sbjct: 137 VPVLLDNYAYFILSCKTKRCAVVDPADPTLVLNMLE 172
>UniRef50_Q47FN7 Cluster: Beta-lactamase-like; n=1; Dechloromonas
aromatica RCB|Rep: Beta-lactamase-like - Dechloromonas
aromatica (strain RCB)
Length = 265
Score = 39.9 bits (89), Expect = 0.075
Identities = 51/180 (28%), Positives = 75/180 (41%), Gaps = 5/180 (2%)
Frame = +3
Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
+++ +PA +DNY++L+ K A +VDP + VL +E G+ L
Sbjct: 2 LEISFIPAFKDNYIWLLT--RGKRAFVVDPGDAAPVLARLEAGGLMLEGILITHHHADHQ 59
Query: 441 GGNEDLIKERPGLIVYG-GDDRIGPSQKKLSTIQSL----KSVT*MYSVFLHPVIQLGIY 605
GG +L K R VY G++ I LS +S+ + VT M +V H + L Y
Sbjct: 60 GGVAEL-KARWQAEVYAPGNESITGCSCPLSGGESIDVLGQKVTVM-AVPGHTLGHLAYY 117
Query: 606 VIS*LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYT 785
LL GDTLF GCG++ A ++C HEYT
Sbjct: 118 APGALLC----------GDTLFGAGCGRLFEGTPAQMSASLDSIAALPGDTLIYCAHEYT 167
>UniRef50_A7JRH0 Cluster: Hydroxyacylglutathione hydrolase; n=3;
Pasteurellaceae|Rep: Hydroxyacylglutathione hydrolase -
Mannheimia haemolytica PHL213
Length = 235
Score = 39.9 bits (89), Expect = 0.075
Identities = 34/144 (23%), Positives = 62/144 (43%)
Frame = +3
Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
+ + +PAL+DNY++ I + ++ I+DP E + L + + +NL
Sbjct: 2 LQITPIPALKDNYIWAI--RNGQDVIIIDPSEHQPALNFIAKNALNLTAILITHNHHDHT 59
Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*L 620
G ++++ P + VYG + + +S Q + Y V +I+ G +
Sbjct: 60 DGVSGIVEQYPNIPVYGPQEVAEFANVIVSPEQHISLFG--YDV---RIIESGGHTAG-H 113
Query: 621 LQKKVTIQLSSPGDTLFLGGCGQV 692
+ GD LF GGCG+V
Sbjct: 114 ISYLFGYDYLFCGDALFSGGCGRV 137
>UniRef50_Q2NGP4 Cluster: Predicted Zn-dependent hydrolase; n=1;
Methanosphaera stadtmanae DSM 3091|Rep: Predicted
Zn-dependent hydrolase - Methanosphaera stadtmanae
(strain DSM 3091)
Length = 225
Score = 39.5 bits (88), Expect = 0.099
Identities = 22/75 (29%), Positives = 38/75 (50%), Gaps = 1/75 (1%)
Frame = +2
Query: 524 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAG-SLK 700
+E+N ++GN ++ L+TP HT+G +CY+ E ++FTG + + S
Sbjct: 119 LENNNVIEVGNWTLKVLYTPGHTSGSVCYY-----EEEKRILFTGDTVYAKGTISDLSYS 173
Query: 701 GTADQMYKALTILSS 745
G K+L L+S
Sbjct: 174 GNYGSYIKSLNTLNS 188
>UniRef50_A5G655 Cluster: Beta-lactamase domain protein; n=1;
Geobacter uraniumreducens Rf4|Rep: Beta-lactamase domain
protein - Geobacter uraniumreducens Rf4
Length = 233
Score = 38.7 bits (86), Expect = 0.17
Identities = 16/44 (36%), Positives = 24/44 (54%)
Frame = +2
Query: 527 EHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTG 658
EH + ++G + CL TP HTTG +CY ++ D+V G
Sbjct: 111 EHLDQIRLGETLINCLLTPGHTTGSMCYLLSHSLFTGDTVFVEG 154
>UniRef50_Q8FYE7 Cluster: Hydroxyacylglutathione hydrolase,
putative; n=19; Bacteria|Rep: Hydroxyacylglutathione
hydrolase, putative - Brucella suis
Length = 257
Score = 38.3 bits (85), Expect = 0.23
Identities = 40/177 (22%), Positives = 68/177 (38%)
Frame = +3
Query: 255 KNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXX 434
+ ++++ DNY LI D + A +D + + A+E +G L
Sbjct: 3 QRLEIEQFICRSDNYGVLIHDPESALTATIDAPDAYAIEAALERRGWTLDFIFTTHHHLD 62
Query: 435 XAGGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS 614
GNE L KE+ G+ + G + T++ T + +F VI +
Sbjct: 63 HVEGNEPL-KEKFGVSIIGPEAEKAKIPGIDRTVKGGDEFT--FGLFKVKVISTPGHTAG 119
Query: 615 *LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYT 785
+ ++ GDTLF GCG++ + A ++CGHEYT
Sbjct: 120 GISYYLPDAKVVFTGDTLFALGCGRLFEGTPATMFHSLEKLVALPGDTALYCGHEYT 176
>UniRef50_A6FY39 Cluster: Probable hydroxyacylglutathione hydrolase;
n=1; Plesiocystis pacifica SIR-1|Rep: Probable
hydroxyacylglutathione hydrolase - Plesiocystis pacifica
SIR-1
Length = 270
Score = 38.3 bits (85), Expect = 0.23
Identities = 44/146 (30%), Positives = 66/146 (45%), Gaps = 9/146 (6%)
Frame = +3
Query: 276 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 455
+P DN+ +L+V +AT EAA +D + VL+ VE G+ L G ++
Sbjct: 1 MPFWTDNFTWLLVCEATGEAAAIDGGVAEPVLEYVEAHGLRLTTILTTHTHPDHIGLHKA 60
Query: 456 LIK-ERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLG-----IYVIS* 617
L K ER G + R+ S+ +L TI L V V++LG + +
Sbjct: 61 LDKAERLGAL------RVVGSRSRLGTIPGLDGPK-GEPVDEGDVVRLGALEGQVMLTEG 113
Query: 618 LLQKKVTI---QLSSPGDTLFLGGCG 686
+ V+ +L GDTLF GGCG
Sbjct: 114 HIDGHVSYRFGELLFCGDTLFAGGCG 139
>UniRef50_Q2JKB1 Cluster: Metallo-beta-lactamase domain protein;
n=14; Bacteria|Rep: Metallo-beta-lactamase domain
protein - Synechococcus sp. (strain JA-2-3B'a(2-13))
(Cyanobacteria bacteriumYellowstone B-Prime)
Length = 238
Score = 37.9 bits (84), Expect = 0.30
Identities = 20/46 (43%), Positives = 28/46 (60%), Gaps = 2/46 (4%)
Frame = +3
Query: 270 KILPALQDNYMYLIVDKATKEAAIVDPV--EPKTVLKAVEEQGVNL 401
++ A Y YLI D AT+EAA+VDPV + + LK + E G+ L
Sbjct: 5 QLFDAETSTYTYLIADPATREAALVDPVLEQVERDLKLIRELGLTL 50
>UniRef50_UPI00006CD5DA Cluster: TNFR/NGFR cysteine-rich region family
protein; n=1; Tetrahymena thermophila SB210|Rep:
TNFR/NGFR cysteine-rich region family protein -
Tetrahymena thermophila SB210
Length = 2129
Score = 37.5 bits (83), Expect = 0.40
Identities = 20/56 (35%), Positives = 26/56 (46%)
Frame = -2
Query: 682 HPPKKSVSPGEDN*IVTFFWSSYEITYMPSCMTGCKKTLYIQVTDFKLCIVLNFFC 515
HP K+ N T F I Y SC+ C K +Y+ T +K CI NF+C
Sbjct: 1824 HPSCKTCVGPNSNQCQTCF--DLLIKYNSSCIVECPKQMYMTQTPYKQCIECNFYC 1877
>UniRef50_Q5FU83 Cluster: Hydroxyacylglutathione hydrolase; n=1;
Gluconobacter oxydans|Rep: Hydroxyacylglutathione
hydrolase - Gluconobacter oxydans (Gluconobacter
suboxydans)
Length = 259
Score = 37.5 bits (83), Expect = 0.40
Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 1/86 (1%)
Frame = +3
Query: 237 PRGPPVKNMDVKILPALQDNYMYLIVDKATK-EAAIVDPVEPKTVLKAVEEQGVNLXXXX 413
PRG V +D+K +P L DNY +L+ AT+ + A+VDP E ++ + + +++
Sbjct: 17 PRGT-VMPLDIKPIPVLSDNYAWLLT--ATEGQRAVVDPGEAGPIMDEIGDGRLDM-ILL 72
Query: 414 XXXXXXXXAGGNEDLIKERPGLIVYG 491
AG D ++ER G VYG
Sbjct: 73 THHHADHTAG--TDALRERYGAKVYG 96
>UniRef50_Q39HP1 Cluster: Hydroxyacylglutathione hydrolase; n=55;
Proteobacteria|Rep: Hydroxyacylglutathione hydrolase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 268
Score = 37.5 bits (83), Expect = 0.40
Identities = 50/184 (27%), Positives = 71/184 (38%), Gaps = 6/184 (3%)
Frame = +3
Query: 276 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 455
+PA DNY++L+ D ++A VDP E V + + E+G L GG
Sbjct: 9 VPAFDDNYIWLVSD--GRDAIAVDPGEAAPVRRVLAERGWRLTAILLTHHHADHVGGVAA 66
Query: 456 LIKERPG---LIVYG-GDDRIGPSQKKLS--TIQSLKSVT*MYSVFLHPVIQLGIYVIS* 617
L +P L VYG + IG + LS +L + + V P G
Sbjct: 67 LRDSQPDDAPLTVYGPAAEAIGVVTRPLSGGDRVTLDAPAATFDVLDVPGHTRGHIAYFQ 126
Query: 618 LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLAGI 797
+ GDTLF GCG++ A + C HEYTL+ I
Sbjct: 127 AAGQGNAAPHVFCGDTLFSCGCGRLFEGTPAQMLASLDALAALPGDTHVHCAHEYTLSNI 186
Query: 798 XKFA 809
+FA
Sbjct: 187 -RFA 189
>UniRef50_Q31H51 Cluster: Metallo-beta-lactamase superfamily protein
precursor; n=1; Thiomicrospira crunogena XCL-2|Rep:
Metallo-beta-lactamase superfamily protein precursor -
Thiomicrospira crunogena (strain XCL-2)
Length = 268
Score = 37.5 bits (83), Expect = 0.40
Identities = 44/181 (24%), Positives = 69/181 (38%), Gaps = 2/181 (1%)
Frame = +3
Query: 261 MDVKILPALQDNYMYLIVDKAT--KEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXX 434
M + LP L DNY ++I + K A IVDP E + V+ EE + L
Sbjct: 1 MKIVGLPTLSDNYTWVIQSENADDKRAWIVDPGESQKVIHYFEENQLQLDGILLTHHHYD 60
Query: 435 XAGGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS 614
G ++ + + GP + ++ V + F VI+ +
Sbjct: 61 HTDGIMGVMDALGEVAIVSNAQ--GPFKPVTHPVKEGDQVQVLNETF--QVIETPGHTDE 116
Query: 615 *LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLAG 794
+ S GDTLF GGCG++ + + A ++CGHEYT A
Sbjct: 117 HICFYHPEALFS--GDTLFTGGCGKIWQNPPEQMAESLLKLRALNDDCMVYCGHEYTYAN 174
Query: 795 I 797
+
Sbjct: 175 L 175
Score = 34.7 bits (76), Expect = 2.8
Identities = 20/82 (24%), Positives = 38/82 (46%)
Frame = +2
Query: 506 RALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMW 685
+ +T V+ + ++ N Q + TP HT HIC++ D+ +FTGG ++W
Sbjct: 86 KPVTHPVKEGDQVQVLNETFQVIETPGHTDEHICFYHPEALFSGDT-LFTGG---CGKIW 141
Query: 686 AGSLKGTADQMYKALTILSSCL 751
+ A+ + K + C+
Sbjct: 142 QNPPEQMAESLLKLRALNDDCM 163
>UniRef50_Q2VZH9 Cluster: Zn-dependent hydrolase, including
glyoxylase; n=2; Magnetospirillum|Rep: Zn-dependent
hydrolase, including glyoxylase - Magnetospirillum
magneticum (strain AMB-1 / ATCC 700264)
Length = 270
Score = 37.5 bits (83), Expect = 0.40
Identities = 37/144 (25%), Positives = 58/144 (40%), Gaps = 2/144 (1%)
Frame = +3
Query: 267 VKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGG 446
V+ +P L DNY+YL + A +DP + VL+ + +G L G
Sbjct: 19 VEQIPVLSDNYVYLAHEPLGGATAAIDPAVSEPVLERLAARGWTLTHILNTHHHGDHTGA 78
Query: 447 NEDLIKERPGLIVYGG--DDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*L 620
N DL + R G V G D P T++ + T M V+++ + +
Sbjct: 79 NLDLAR-RTGCAVVGAARDSERIPG----ITLEVSEGETFMLGHAAVTVLEVPGHTSGHV 133
Query: 621 LQKKVTIQLSSPGDTLFLGGCGQV 692
+ GDTLF GCG++
Sbjct: 134 AYWLADSHVLFCGDTLFSLGCGRL 157
Score = 37.1 bits (82), Expect = 0.53
Identities = 23/73 (31%), Positives = 36/73 (49%)
Frame = +2
Query: 512 LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAG 691
+T +V F +G+ V L P HT+GH+ Y++ DS V G TL
Sbjct: 103 ITLEVSEGETFMLGHAAVTVLEVPGHTSGHVAYWLA------DSHVLFCGDTLFSLGCGR 156
Query: 692 SLKGTADQMYKAL 730
+GTA++M+ +L
Sbjct: 157 LFEGTAEEMWASL 169
>UniRef50_A0DY50 Cluster: Chromosome undetermined scaffold_7, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_7,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 489
Score = 37.5 bits (83), Expect = 0.40
Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
Frame = +2
Query: 512 LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAG 691
++K + N K+G + +Q L TP HT C F+ EEG ++TG L +
Sbjct: 130 ISKVMNDNEFLKVGKVKIQALHTPGHTQESTC-FLLYDEEGKQHSIYTGDTLFLGEVGRP 188
Query: 692 SLKGTAD-QMYKALTILSSCL 751
L +D Y ++L + L
Sbjct: 189 DLAVKSDVTQYDLASLLYASL 209
>UniRef50_Q97GU3 Cluster: Predicted Zn-dependent hydrolase of
metallo-beta-lactamase superfamily; n=1; Clostridium
acetobutylicum|Rep: Predicted Zn-dependent hydrolase of
metallo-beta-lactamase superfamily - Clostridium
acetobutylicum
Length = 199
Score = 37.1 bits (82), Expect = 0.53
Identities = 14/34 (41%), Positives = 21/34 (61%)
Frame = +2
Query: 515 TKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 616
TK V+ + + G L ++C+ TP HT G +CY V
Sbjct: 101 TKYVDDGDELQFGELKIKCIKTPGHTPGGMCYLV 134
>UniRef50_A6FA17 Cluster: Hydroxyacylglutathione hydrolase; n=1;
Moritella sp. PE36|Rep: Hydroxyacylglutathione hydrolase
- Moritella sp. PE36
Length = 258
Score = 37.1 bits (82), Expect = 0.53
Identities = 31/145 (21%), Positives = 58/145 (40%)
Frame = +3
Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
++V +P DNY++LI + IVDP + VL+ + +Q + L
Sbjct: 2 LEVISIPTFNDNYVWLIKNTENNHCCIVDPGQADPVLQVINQQNLILEAILITHHHYDHI 61
Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*L 620
G D++ + I ++ + + + + V+ + +
Sbjct: 62 DGISDILNASTNPVQVYSSIAI-DVDAPVTLVTENSQLNLLNNSLALTVMATPGHKREHV 120
Query: 621 LQKKVTIQLSSPGDTLFLGGCGQVL 695
+ T+ S GDTLF GGCG++L
Sbjct: 121 VYYNQTMLFS--GDTLFSGGCGRLL 143
>UniRef50_Q6ML19 Cluster: Hydroxyacylglutathione hydrolase GloB;
n=1; Bdellovibrio bacteriovorus|Rep:
Hydroxyacylglutathione hydrolase GloB - Bdellovibrio
bacteriovorus
Length = 251
Score = 36.7 bits (81), Expect = 0.70
Identities = 15/49 (30%), Positives = 29/49 (59%)
Frame = +3
Query: 255 KNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNL 401
K V+++P DNY++++ D AT++A VDP + V+ + ++L
Sbjct: 3 KKEHVELVPIFDDNYVFILTDDATQKAVAVDPGDAGPVIDFLRANKLDL 51
>UniRef50_Q7MUF5 Cluster: Metallo-beta-lactamase superfamily
protein; n=6; Bacteroidetes|Rep: Metallo-beta-lactamase
superfamily protein - Porphyromonas gingivalis
(Bacteroides gingivalis)
Length = 471
Score = 36.3 bits (80), Expect = 0.93
Identities = 16/44 (36%), Positives = 26/44 (59%)
Frame = +2
Query: 527 EHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTG 658
E N F++GN+ ++ L TP HT C F+ E G ++ +F+G
Sbjct: 90 EDNQIFELGNVKIRVLHTPGHTMESSC-FLLIDENGREAALFSG 132
>UniRef50_A6FTG4 Cluster: Beta-lactamase-like protein; n=1;
Roseobacter sp. AzwK-3b|Rep: Beta-lactamase-like protein
- Roseobacter sp. AzwK-3b
Length = 306
Score = 36.3 bits (80), Expect = 0.93
Identities = 16/38 (42%), Positives = 22/38 (57%)
Frame = +2
Query: 503 DRALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 616
DR + E FK+GNL+V+ + +P HT G I Y V
Sbjct: 127 DRDFDRLFEDGDTFKLGNLDVRVMLSPGHTLGSITYVV 164
>UniRef50_A0UWD4 Cluster: Beta-lactamase-like; n=1; Clostridium
cellulolyticum H10|Rep: Beta-lactamase-like -
Clostridium cellulolyticum H10
Length = 235
Score = 36.3 bits (80), Expect = 0.93
Identities = 14/45 (31%), Positives = 24/45 (53%)
Frame = +2
Query: 524 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTG 658
V+ K+G +++C+ TP HT G +C+FV D++ G
Sbjct: 112 VQDGEVIKLGYTDIKCILTPGHTMGGMCFFVDGSLFTGDTIFMEG 156
>UniRef50_Q892B0 Cluster: Hydroxyacylglutathione hydrolase; n=3;
Clostridium|Rep: Hydroxyacylglutathione hydrolase -
Clostridium tetani
Length = 201
Score = 35.9 bits (79), Expect = 1.2
Identities = 14/46 (30%), Positives = 28/46 (60%)
Frame = +2
Query: 521 KVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTG 658
K++ FKIG+ ++C+ TP H+ G +C+ + ++++FTG
Sbjct: 105 KIKEGDTFKIGDKEIKCIETPGHSLGGMCFLI-------ENIIFTG 143
>UniRef50_Q41EG0 Cluster: Beta-lactamase-like:Rhodanese-like; n=4;
Bacteria|Rep: Beta-lactamase-like:Rhodanese-like -
Exiguobacterium sibiricum 255-15
Length = 468
Score = 35.9 bits (79), Expect = 1.2
Identities = 14/52 (26%), Positives = 27/52 (51%)
Frame = +2
Query: 518 KKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLL 673
K V +FK+GN+ + + TP HT H+ + + ++ +FTG + +
Sbjct: 97 KLVTDGNRFKVGNVTFEVMHTPGHTPEHVSFLLYDRDQTVPMGIFTGDFVFV 148
>UniRef50_A0YF48 Cluster: Hydroxyacylglutathione hydrolase; n=2;
unclassified Gammaproteobacteria (miscellaneous)|Rep:
Hydroxyacylglutathione hydrolase - marine gamma
proteobacterium HTCC2143
Length = 258
Score = 35.9 bits (79), Expect = 1.2
Identities = 21/65 (32%), Positives = 31/65 (47%)
Frame = +2
Query: 557 LNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGSLKGTADQMYKALTI 736
+ ++ L TP HT H+C+ V E+G + VFTG TL G D +Y+ +
Sbjct: 104 VQLRVLDTPGHTYAHLCFLVL--EQGIEVAVFTGD-TLFNAGVGHCRSGDVDSLYQTIAE 160
Query: 737 LSSCL 751
CL
Sbjct: 161 QFHCL 165
>UniRef50_Q8EE27 Cluster: Metallo-beta-lactamase family protein;
n=14; Proteobacteria|Rep: Metallo-beta-lactamase family
protein - Shewanella oneidensis
Length = 267
Score = 35.5 bits (78), Expect = 1.6
Identities = 21/51 (41%), Positives = 26/51 (50%)
Frame = +3
Query: 657 GDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLAGIXKFA 809
GDTLF GGCG++ C A ++C HEYTLA + KFA
Sbjct: 137 GDTLFSGGCGRLFEGTPAQMCHSLRLLAALPAETRVYCAHEYTLANL-KFA 186
>UniRef50_Q62DP8 Cluster: Metallo-beta-lactamase family protein;
n=17; Proteobacteria|Rep: Metallo-beta-lactamase family
protein - Burkholderia mallei (Pseudomonas mallei)
Length = 246
Score = 35.5 bits (78), Expect = 1.6
Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 5/81 (6%)
Frame = +2
Query: 518 KKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLL-----RRM 682
K VE + ++GN+ ++ L TP HT HI VT + + G+TL+ R
Sbjct: 89 KGVEDGDEIRVGNVVIKVLETPGHTPEHISLLVTDRTRAEEPWLALTGHTLMIGDLGRTE 148
Query: 683 WAGSLKGTADQMYKALTILSS 745
A S + A +++++ L S
Sbjct: 149 LAESAEAGARNLFRSVRTLKS 169
>UniRef50_Q7X477 Cluster: AhlK; n=12; Proteobacteria|Rep: AhlK -
Klebsiella pneumoniae
Length = 264
Score = 35.5 bits (78), Expect = 1.6
Identities = 14/40 (35%), Positives = 22/40 (55%)
Frame = +2
Query: 551 GNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTL 670
G+ +QC+FTP H+ GH + + P N ++ YTL
Sbjct: 169 GDGTLQCIFTPGHSPGHQSFLIRLPGGTNFTLAIDAAYTL 208
>UniRef50_Q0LPD2 Cluster: Beta-lactamase-like; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Beta-lactamase-like -
Herpetosiphon aurantiacus ATCC 23779
Length = 464
Score = 35.5 bits (78), Expect = 1.6
Identities = 14/46 (30%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
Frame = +2
Query: 524 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSV-VFTG 658
+ + +GNL ++ L TP HT H+ + +T G++ + +FTG
Sbjct: 100 INDGDSWMVGNLKIEVLHTPGHTPEHVIFMLTDTPAGDEPMGIFTG 145
>UniRef50_Q3SIB0 Cluster: Hydroxyacylglutathione hydrolase; n=1;
Thiobacillus denitrificans ATCC 25259|Rep:
Hydroxyacylglutathione hydrolase - Thiobacillus
denitrificans (strain ATCC 25259)
Length = 256
Score = 35.1 bits (77), Expect = 2.1
Identities = 21/75 (28%), Positives = 36/75 (48%)
Frame = +3
Query: 276 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 455
LPA +DNY+++ D K A VDP +P + ++ +G+ L GGN
Sbjct: 7 LPAFEDNYIWVWHD--AKYAVAVDPGDPAVLSTYLDSRGLALAAVLVTHHHRDHTGGN-T 63
Query: 456 LIKERPGLIVYGGDD 500
+++R +Y D+
Sbjct: 64 WLRQRYNCAIYAPDN 78
>UniRef50_Q0FEW8 Cluster: Putative hydroxyacylglutathione hydrolase
(Glyoxalase II) (GLX II) protein; n=1; alpha
proteobacterium HTCC2255|Rep: Putative
hydroxyacylglutathione hydrolase (Glyoxalase II) (GLX
II) protein - alpha proteobacterium HTCC2255
Length = 255
Score = 35.1 bits (77), Expect = 2.1
Identities = 21/69 (30%), Positives = 30/69 (43%)
Frame = +3
Query: 258 NMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXX 437
++ V I+P L DNY YLI + T A++D + +L + E G L
Sbjct: 2 SLSVIIVPCLIDNYAYLIRCEETGHTAVIDVPDAYPILNMINELGWKLNSILITHHHSDH 61
Query: 438 AGGNEDLIK 464
G E L K
Sbjct: 62 VDGVEQLQK 70
>UniRef50_A1HQX4 Cluster: Beta-lactamase domain protein; n=1;
Thermosinus carboxydivorans Nor1|Rep: Beta-lactamase
domain protein - Thermosinus carboxydivorans Nor1
Length = 332
Score = 35.1 bits (77), Expect = 2.1
Identities = 16/49 (32%), Positives = 25/49 (51%)
Frame = +2
Query: 524 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTL 670
V + IG+ C+ TP HT GH+C + E N ++F+G + L
Sbjct: 149 VREGYRLVIGDYEFTCITTPGHTPGHVCLY-----EPNRKILFSGDHIL 192
>UniRef50_Q8SSH0 Cluster: HYDROXYACYL GLUTATHION HYDROLASE; n=1;
Encephalitozoon cuniculi|Rep: HYDROXYACYL GLUTATHION
HYDROLASE - Encephalitozoon cuniculi
Length = 263
Score = 35.1 bits (77), Expect = 2.1
Identities = 10/26 (38%), Positives = 17/26 (65%)
Frame = +2
Query: 539 KFKIGNLNVQCLFTPCHTTGHICYFV 616
KF+ ++ ++C TPCHT C++V
Sbjct: 124 KFRFKDVEIECFHTPCHTVDSFCFYV 149
>UniRef50_Q3E6L0 Cluster: Beta-lactamase-like:Rhodanese-like; n=2;
Chloroflexus|Rep: Beta-lactamase-like:Rhodanese-like -
Chloroflexus aurantiacus J-10-fl
Length = 466
Score = 34.7 bits (76), Expect = 2.8
Identities = 16/48 (33%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Frame = +2
Query: 524 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSV-VFTGGY 664
V+ + +GN+ VQ + TP HT HI + +T + + VFTG +
Sbjct: 99 VKDGDTWMVGNIKVQVIATPGHTPEHIAFMITDTAGADQPMGVFTGDF 146
>UniRef50_A6DU41 Cluster: Metallo-beta-lactamase family protein;
n=1; Lentisphaera araneosa HTCC2155|Rep:
Metallo-beta-lactamase family protein - Lentisphaera
araneosa HTCC2155
Length = 222
Score = 34.7 bits (76), Expect = 2.8
Identities = 15/33 (45%), Positives = 22/33 (66%), Gaps = 1/33 (3%)
Frame = +3
Query: 291 DNYMYLIVDKATKEAAIVDPV-EPKTVLKAVEE 386
DN++YLI DK T + A+VDP + + +A EE
Sbjct: 13 DNFIYLIKDKKTSDIAVVDPAWDVDAIFRAAEE 45
>UniRef50_Q9UZT9 Cluster: Hydroxyacylglutathione hydrolase related;
n=4; Thermococcaceae|Rep: Hydroxyacylglutathione
hydrolase related - Pyrococcus abyssi
Length = 222
Score = 34.7 bits (76), Expect = 2.8
Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 1/76 (1%)
Frame = +2
Query: 521 KVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGSL- 697
K+E + K+G + ++ + TP HT G C + EE + ++FTG L L
Sbjct: 123 KLEDGDEIKVGKVKLRLIHTPGHTRGSSCLYY---EE--ERIMFTGDTVFLGTYGRTDLP 177
Query: 698 KGTADQMYKALTILSS 745
G D++ ++L +L S
Sbjct: 178 TGNEDKIVESLELLKS 193
>UniRef50_Q8KAV6 Cluster: Hydroxyacylglutathione hydrolase,
putative; n=10; Chlorobiaceae|Rep:
Hydroxyacylglutathione hydrolase, putative - Chlorobium
tepidum
Length = 215
Score = 34.3 bits (75), Expect = 3.7
Identities = 20/55 (36%), Positives = 25/55 (45%), Gaps = 1/55 (1%)
Frame = +3
Query: 294 NYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 455
N+ YL DKAT EA VDP PK ++ A +G L GNE+
Sbjct: 15 NFGYLCADKATGEAFAVDPSNSPKVLVDAAARKGWQLVRAFCTHGHADHTNGNEE 69
>UniRef50_Q5LNN5 Cluster: Hydroxyacylglutathione hydrolase,
putative; n=4; Rhodobacteraceae|Rep:
Hydroxyacylglutathione hydrolase, putative -
Silicibacter pomeroyi
Length = 255
Score = 34.3 bits (75), Expect = 3.7
Identities = 15/47 (31%), Positives = 26/47 (55%)
Frame = +3
Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNL 401
+++ +P L DNY YLI D + A+VD E + ++ +G +L
Sbjct: 3 LEIVTVPCLSDNYAYLIHDADAGKTALVDAPEAAPIQSELDRRGWSL 49
>UniRef50_Q2NVG1 Cluster: Putative hydroxyacylglutathione hydrolase;
n=1; Sodalis glossinidius str. 'morsitans'|Rep: Putative
hydroxyacylglutathione hydrolase - Sodalis glossinidius
(strain morsitans)
Length = 250
Score = 34.3 bits (75), Expect = 3.7
Identities = 21/80 (26%), Positives = 40/80 (50%)
Frame = +3
Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
M++ +PAL DNY++L+ + +VDP + VL+A+ + +
Sbjct: 1 MNLISIPALADNYIWLL-HNDDRRCLVVDPGDATPVLQALADHRLTPVAVLLTHHHQDHV 59
Query: 441 GGNEDLIKERPGLIVYGGDD 500
GG +L++ P + VYG ++
Sbjct: 60 GGVSELLQHFP-VPVYGPEE 78
>UniRef50_Q23CX3 Cluster: Metallo-beta-lactamase superfamily
protein; n=1; Tetrahymena thermophila SB210|Rep:
Metallo-beta-lactamase superfamily protein - Tetrahymena
thermophila SB210
Length = 321
Score = 34.3 bits (75), Expect = 3.7
Identities = 13/36 (36%), Positives = 20/36 (55%)
Frame = +2
Query: 503 DRALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICY 610
D K+ ++ T + G + L+ PCHTTGH+ Y
Sbjct: 119 DNPNDKETKNETSIE-GEFQIDFLYVPCHTTGHVLY 153
>UniRef50_Q483N7 Cluster: Metallo-beta-lactamase family protein;
n=2; Alteromonadales|Rep: Metallo-beta-lactamase family
protein - Colwellia psychrerythraea (strain 34H / ATCC
BAA-681) (Vibriopsychroerythus)
Length = 265
Score = 33.9 bits (74), Expect = 4.9
Identities = 25/68 (36%), Positives = 33/68 (48%), Gaps = 4/68 (5%)
Frame = +2
Query: 563 VQCLFT----PCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGSLKGTADQMYKAL 730
+ C FT P HT GHI Y+ ND +VF G TL +GT QM+ +L
Sbjct: 110 LDCQFTVLDLPGHTKGHIAYY-------NDKMVFCGD-TLFSGGCGRLFEGTPQQMHHSL 161
Query: 731 TILSSCLT 754
T L++ T
Sbjct: 162 TKLANLAT 169
>UniRef50_A6LR94 Cluster: Beta-lactamase domain protein; n=1;
Clostridium beijerinckii NCIMB 8052|Rep: Beta-lactamase
domain protein - Clostridium beijerinckii NCIMB 8052
Length = 224
Score = 33.9 bits (74), Expect = 4.9
Identities = 22/94 (23%), Positives = 45/94 (47%), Gaps = 1/94 (1%)
Frame = +2
Query: 524 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGSLK- 700
V + K IG L + C+ TP HT G +C+ + ++ +FTG +R + K
Sbjct: 100 VNDSDKISIGKLKMDCVLTPGHTAGGMCFKL-------ENKLFTGDTIFIRGCGICTCKG 152
Query: 701 GTADQMYKALTILSSCLTTLNVLWP*VHFGRNXK 802
G ++M++++ + +++P +F + K
Sbjct: 153 GDYNEMFESIKKIKEIAKKNVLIYPGHYFEGDLK 186
>UniRef50_A1ASA4 Cluster: Beta-lactamase domain protein; n=2;
Bacteria|Rep: Beta-lactamase domain protein - Pelobacter
propionicus (strain DSM 2379)
Length = 253
Score = 33.9 bits (74), Expect = 4.9
Identities = 13/33 (39%), Positives = 21/33 (63%)
Frame = +2
Query: 515 TKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYF 613
TK ++ N +GN +Q L TP H+ GH+C++
Sbjct: 130 TKVLKDNDVIDMGNRCIQVLHTPGHSPGHMCFW 162
>UniRef50_A0L873 Cluster: Hydroxyacylglutathione hydrolase; n=1;
Magnetococcus sp. MC-1|Rep: Hydroxyacylglutathione
hydrolase - Magnetococcus sp. (strain MC-1)
Length = 254
Score = 33.9 bits (74), Expect = 4.9
Identities = 22/66 (33%), Positives = 31/66 (46%)
Frame = +2
Query: 542 FKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGSLKGTADQMY 721
F +G V TP HT+GH+CY + +F G TL +GT QM+
Sbjct: 100 FCLGPHQVDTYHTPGHTSGHLCYHIA-------DCLFAGD-TLFSYGCGRLFEGTPQQMW 151
Query: 722 KALTIL 739
++L IL
Sbjct: 152 QSLLIL 157
>UniRef50_Q236K6 Cluster: Metallo-beta-lactamase superfamily
protein; n=1; Tetrahymena thermophila SB210|Rep:
Metallo-beta-lactamase superfamily protein - Tetrahymena
thermophila SB210
Length = 498
Score = 33.9 bits (74), Expect = 4.9
Identities = 17/66 (25%), Positives = 31/66 (46%)
Frame = +2
Query: 521 KVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGSLK 700
+ + N IG + +Q L+TP HT C+ + ++ +FTG L +L
Sbjct: 118 QAKDNEIISIGKIKMQVLYTPGHTNESTCFLLL--DDERQHAIFTGDTLYLEEASFPNLA 175
Query: 701 GTADQM 718
T++Q+
Sbjct: 176 ATSEQI 181
>UniRef50_A7D114 Cluster: Beta-lactamase domain protein; n=4;
Halobacteriaceae|Rep: Beta-lactamase domain protein -
Halorubrum lacusprofundi ATCC 49239
Length = 402
Score = 33.9 bits (74), Expect = 4.9
Identities = 23/78 (29%), Positives = 36/78 (46%)
Frame = +2
Query: 524 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGSLKG 703
VE +F +G+ V+ +FTP HTTG Y + DS++ TG + + L+
Sbjct: 228 VEDGDEFTVGDATVETVFTPGHTTGMTSYLL------GDSLLATGDGLFIESVARPDLEE 281
Query: 704 TADQMYKALTILSSCLTT 757
D +A +L L T
Sbjct: 282 GDDGAPEAARMLYDSLQT 299
>UniRef50_Q2SJ47 Cluster: Zn-dependent Hydrolase, including
glyoxylases; n=1; Hahella chejuensis KCTC 2396|Rep:
Zn-dependent Hydrolase, including glyoxylases - Hahella
chejuensis (strain KCTC 2396)
Length = 257
Score = 33.5 bits (73), Expect = 6.5
Identities = 21/72 (29%), Positives = 34/72 (47%)
Frame = +3
Query: 276 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 455
+PA DNY++ I +A +VDP + + VL+ + E + L GG +
Sbjct: 7 IPAFNDNYIWSI-QSDQGDAWVVDPGDAQPVLRHLAENHLTLRGILITHHHHDHTGGVNE 65
Query: 456 LIKERPGLIVYG 491
L+ P + VYG
Sbjct: 66 LLANHP-VPVYG 76
>UniRef50_Q1NKM3 Cluster: Beta-lactamase-like; n=3;
Deltaproteobacteria|Rep: Beta-lactamase-like - delta
proteobacterium MLMS-1
Length = 213
Score = 33.5 bits (73), Expect = 6.5
Identities = 15/38 (39%), Positives = 21/38 (55%)
Frame = +2
Query: 548 IGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGG 661
+G + +Q + TP HT G IC + TAP +F GG
Sbjct: 118 LGTIELQVIHTPGHTPGGICLY-TAPHLFTGDTLFVGG 154
>UniRef50_Q04RQ6 Cluster: Zn-dependent hydrolase; n=3;
Leptospira|Rep: Zn-dependent hydrolase - Leptospira
borgpetersenii serovar Hardjo-bovis (strain JB197)
Length = 269
Score = 33.5 bits (73), Expect = 6.5
Identities = 18/72 (25%), Positives = 32/72 (44%)
Frame = +3
Query: 294 NYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERP 473
N+ Y++ + T E +DP + + + K ++ +G L GN L+ +R
Sbjct: 14 NFTYILRNSETSETLSIDPYDSEQIEKFLDSKGWTLDFLLNTHEHEDHTSGNTGLV-QRY 72
Query: 474 GLIVYGGDDRIG 509
G VY + IG
Sbjct: 73 GCTVYSHPEGIG 84
>UniRef50_A6DNT9 Cluster: Beta-lactamase-like protein; n=1;
Lentisphaera araneosa HTCC2155|Rep: Beta-lactamase-like
protein - Lentisphaera araneosa HTCC2155
Length = 213
Score = 33.5 bits (73), Expect = 6.5
Identities = 15/52 (28%), Positives = 29/52 (55%)
Frame = +2
Query: 524 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRR 679
+E + F+ G ++ + TP H+ G C+ + E ++ ++F+G TL RR
Sbjct: 112 IEDSQSFEFGEFKLEAIHTPGHSAGSTCFKI---ENSDEQLLFSGD-TLFRR 159
>UniRef50_Q10428 Cluster: Serine/threonine-protein phosphatase 2A 56
kDa regulatory subunit delta 1 isoform; n=25;
Fungi/Metazoa group|Rep: Serine/threonine-protein
phosphatase 2A 56 kDa regulatory subunit delta 1 isoform
- Schizosaccharomyces pombe (Fission yeast)
Length = 548
Score = 33.5 bits (73), Expect = 6.5
Identities = 18/63 (28%), Positives = 33/63 (52%)
Frame = -3
Query: 819 YVSRQIXKFLPKCTHGHKTFSVVRQLLRIVNALYI*SAVPFKEPAHIRLRRVYPPVKTTE 640
++ R I + + ++ F+ + +LL I+ ++ A+P KE I L RV P+ +
Sbjct: 278 FIRRSINNLFLQFVYENEQFNGIAELLEILGSIINGFALPLKEEHKIFLSRVLIPLHKAK 337
Query: 639 SLP 631
SLP
Sbjct: 338 SLP 340
>UniRef50_Q9AAS7 Cluster: Hydroxyacylglutathione hydrolase,
putative; n=4; cellular organisms|Rep:
Hydroxyacylglutathione hydrolase, putative - Caulobacter
crescentus (Caulobacter vibrioides)
Length = 249
Score = 33.1 bits (72), Expect = 8.6
Identities = 20/73 (27%), Positives = 35/73 (47%)
Frame = +2
Query: 512 LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAG 691
L + V + +G+ + + T HT GH+ Y+ + D++ F G TL
Sbjct: 88 LDRVVRDGEEVMLGDTRLTVIDTGGHTLGHVSYY-----DAEDAIAFVGD-TLFALGCGR 141
Query: 692 SLKGTADQMYKAL 730
+GTA+QM+ +L
Sbjct: 142 LFEGTAEQMWDSL 154
>UniRef50_Q1ARM7 Cluster: Beta-lactamase-like protein; n=1;
Rubrobacter xylanophilus DSM 9941|Rep:
Beta-lactamase-like protein - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 266
Score = 33.1 bits (72), Expect = 8.6
Identities = 17/44 (38%), Positives = 25/44 (56%)
Frame = +2
Query: 503 DRALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEG 634
+R L ++++ + + G V LFTP HT GH+ Y V PE G
Sbjct: 155 ERILWRELDGDAELAPG---VWALFTPGHTPGHMSYRVDLPESG 195
>UniRef50_A6TKP6 Cluster: Beta-lactamase domain protein; n=1;
Alkaliphilus metalliredigens QYMF|Rep: Beta-lactamase
domain protein - Alkaliphilus metalliredigens QYMF
Length = 207
Score = 33.1 bits (72), Expect = 8.6
Identities = 18/67 (26%), Positives = 30/67 (44%)
Frame = +2
Query: 524 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGSLKG 703
+ H +G L ++ + TP HT G IC V ++ V+FTG + L G
Sbjct: 110 LSHGDTISVGALQLEVIHTPGHTPGSICLAVK-----DEKVIFTGDTVFSDALGRTDLAG 164
Query: 704 TADQMYK 724
++ M +
Sbjct: 165 GSEAMLR 171
>UniRef50_A1U0H3 Cluster: Beta-lactamase domain protein; n=1;
Marinobacter aquaeolei VT8|Rep: Beta-lactamase domain
protein - Marinobacter aquaeolei (strain ATCC 700491 /
DSM 11845 / VT8)(Marinobacter hydrocarbonoclasticus
(strain DSM 11845))
Length = 186
Score = 33.1 bits (72), Expect = 8.6
Identities = 13/29 (44%), Positives = 17/29 (58%)
Frame = +2
Query: 524 VEHNTKFKIGNLNVQCLFTPCHTTGHICY 610
VE F++G L+ Q + TP HT GH Y
Sbjct: 92 VEEGRPFQVGRLSFQPIHTPGHTDGHFAY 120
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 757,022,057
Number of Sequences: 1657284
Number of extensions: 14356677
Number of successful extensions: 33827
Number of sequences better than 10.0: 115
Number of HSP's better than 10.0 without gapping: 32408
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 33706
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 70914189703
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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