Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= e40h0960
(841 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein ty... 128 2e-28
UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2; Cul... 126 5e-28
UniRef50_UPI0000D57699 Cluster: PREDICTED: similar to CG18247-PA... 121 2e-26
UniRef50_Q24145 Cluster: Tyrosine-protein kinase shark; n=2; Sop... 100 4e-20
UniRef50_P03949 Cluster: Tyrosine-protein kinase abl-1; n=5; Cae... 69 1e-10
UniRef50_P53356 Cluster: Tyrosine-protein kinase HTK16; n=1; Hyd... 69 1e-10
UniRef50_UPI0000E48523 Cluster: PREDICTED: similar to protein-ty... 69 2e-10
UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monos... 69 2e-10
UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 66 8e-10
UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2; Culicidae... 66 8e-10
UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21; Deut... 66 8e-10
UniRef50_UPI0000E497E3 Cluster: PREDICTED: similar to protein-ty... 66 1e-09
UniRef50_P29349 Cluster: Tyrosine-protein phosphatase corkscrew;... 66 1e-09
UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP099... 65 2e-09
UniRef50_UPI000058445F Cluster: PREDICTED: similar to SH2/SH3 ad... 65 2e-09
UniRef50_Q4SIP6 Cluster: Chromosome 21 SCAF14577, whole genome s... 65 2e-09
UniRef50_A2AAH7 Cluster: Growth factor receptor bound protein 2;... 64 3e-09
UniRef50_P62993 Cluster: Growth factor receptor-bound protein 2;... 64 3e-09
UniRef50_Q98TP5 Cluster: C-Src protein-tyrosine kinase; n=5; Eut... 64 6e-09
UniRef50_Q9Y1Y2 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 64 6e-09
UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosi... 63 7e-09
UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to proto-onco... 63 1e-08
UniRef50_A7SCW1 Cluster: Predicted protein; n=1; Nematostella ve... 63 1e-08
UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1; n... 63 1e-08
UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5; Eumet... 63 1e-08
UniRef50_Q13322-2 Cluster: Isoform 1 of Q13322 ; n=5; Homo/Pan/G... 62 1e-08
UniRef50_O88890 Cluster: SH2 domain-containing protein 1A; n=8; ... 62 1e-08
UniRef50_Q13322 Cluster: Growth factor receptor-bound protein 10... 62 1e-08
UniRef50_UPI0000F201D0 Cluster: PREDICTED: hypothetical protein;... 62 2e-08
UniRef50_Q7YZX2 Cluster: Bruton's tyrosine kinase-like protein; ... 62 2e-08
UniRef50_Q9Y1X9 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 61 3e-08
UniRef50_A2RQD7 Cluster: Bcr-abl1 e19a2 chimeric protein; n=2; H... 61 3e-08
UniRef50_Q13588 Cluster: GRB2-related adapter protein; n=21; Bil... 61 3e-08
UniRef50_Q9BL77 Cluster: C-terminal src kinase protein 1; n=2; C... 61 4e-08
UniRef50_Q5BXT3 Cluster: SJCHGC03955 protein; n=1; Schistosoma j... 61 4e-08
UniRef50_A2RQD6 Cluster: Bcr-abl1 e6a2 chimeric protein; n=10; E... 61 4e-08
UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase ... 61 4e-08
UniRef50_UPI0000F2E785 Cluster: PREDICTED: hypothetical protein;... 60 5e-08
UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming pr... 60 5e-08
UniRef50_A2RQD3 Cluster: Bcr-abl1 e13a3 chimeric protein; n=21; ... 60 7e-08
UniRef50_Q06124 Cluster: Tyrosine-protein phosphatase non-recept... 60 7e-08
UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming pr... 60 7e-08
UniRef50_O60880 Cluster: SH2 domain-containing protein 1A; n=18;... 60 9e-08
UniRef50_Q5ZM15 Cluster: Putative uncharacterized protein; n=3; ... 59 1e-07
UniRef50_Q7PV64 Cluster: ENSANGP00000020137; n=5; Coelomata|Rep:... 59 1e-07
UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-prote... 59 1e-07
UniRef50_P42685 Cluster: Tyrosine-protein kinase FRK; n=27; Fung... 59 2e-07
UniRef50_Q6DEM2 Cluster: V-crk sarcoma virus CT10 oncogene homol... 58 2e-07
UniRef50_Q7QHE3 Cluster: ENSANGP00000022029; n=2; Anopheles gamb... 58 2e-07
UniRef50_UPI0000E479E4 Cluster: PREDICTED: similar to Sh2d3c-pro... 58 3e-07
UniRef50_Q7QG48 Cluster: ENSANGP00000010943; n=1; Anopheles gamb... 58 3e-07
UniRef50_Q0PIN0 Cluster: Bam32; n=1; Branchiostoma belcheri tsin... 58 3e-07
UniRef50_Q22070 Cluster: Putative uncharacterized protein plc-3;... 58 4e-07
UniRef50_Q5T185 Cluster: SHC (Src homology 2 domain containing) ... 58 4e-07
UniRef50_Q59HB0 Cluster: SHC (Src homology 2 domain containing) ... 58 4e-07
UniRef50_O15357 Cluster: Phosphatidylinositol-3,4,5-trisphosphat... 58 4e-07
UniRef50_P29353 Cluster: SHC-transforming protein 1; n=46; Tetra... 58 4e-07
UniRef50_UPI0000E46C42 Cluster: PREDICTED: similar to Grb14; n=2... 57 5e-07
UniRef50_UPI00015A4B5A Cluster: protein tyrosine phosphatase, no... 57 5e-07
UniRef50_Q8WPV5 Cluster: Tyrosine kinase; n=2; Eumetazoa|Rep: Ty... 57 5e-07
UniRef50_P98077 Cluster: SHC-transforming protein 2; n=15; Tetra... 57 5e-07
UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38; Eut... 57 5e-07
UniRef50_Q8BZ27 Cluster: Adult female vagina cDNA, RIKEN full-le... 57 6e-07
UniRef50_O77440 Cluster: Protein-tyrosine kinase HTK98; n=1; Hyd... 57 6e-07
UniRef50_P20936 Cluster: Ras GTPase-activating protein 1; n=50; ... 57 6e-07
UniRef50_O75791 Cluster: GRB2-related adapter protein 2; n=22; A... 57 6e-07
UniRef50_UPI00006A0BC0 Cluster: Growth factor receptor-bound pro... 56 8e-07
UniRef50_UPI000065EFEA Cluster: Growth factor receptor-bound pro... 56 8e-07
UniRef50_Q4SS18 Cluster: Chromosome undetermined SCAF14482, whol... 56 8e-07
UniRef50_P16591 Cluster: Proto-oncogene tyrosine-protein kinase ... 56 8e-07
UniRef50_Q9UN19 Cluster: Dual adapter for phosphotyrosine and 3-... 56 8e-07
UniRef50_UPI00015B564A Cluster: PREDICTED: similar to CRK protei... 56 1e-06
UniRef50_P43405 Cluster: Tyrosine-protein kinase SYK; n=23; Ther... 55 2e-06
UniRef50_Q9XYM0 Cluster: Adapter molecule Crk; n=7; Endopterygot... 55 2e-06
UniRef50_UPI000065FE19 Cluster: SHC-transforming protein 1 (SH2 ... 54 3e-06
UniRef50_Q4TEC1 Cluster: Chromosome undetermined SCAF5507, whole... 54 3e-06
UniRef50_Q4SVT4 Cluster: Chromosome undetermined SCAF13726, whol... 54 3e-06
UniRef50_Q4RIB1 Cluster: Chromosome 8 SCAF15044, whole genome sh... 54 3e-06
UniRef50_UPI0000D562ED Cluster: PREDICTED: similar to growth fac... 54 4e-06
UniRef50_Q1LWW1 Cluster: Novel protein similar to vertebrate pho... 54 4e-06
UniRef50_P29350 Cluster: Tyrosine-protein phosphatase non-recept... 54 4e-06
UniRef50_P05433 Cluster: P47(GAG-CRK) protein; n=3; root|Rep: P4... 54 4e-06
UniRef50_UPI0000660CF8 Cluster: Crk-like protein.; n=3; Euteleos... 54 6e-06
UniRef50_Q4S8K3 Cluster: Chromosome 2 SCAF14705, whole genome sh... 54 6e-06
UniRef50_Q4RP74 Cluster: Chromosome 1 SCAF15008, whole genome sh... 54 6e-06
UniRef50_Q92529 Cluster: SHC-transforming protein 3; n=34; Eutel... 54 6e-06
UniRef50_UPI0000D57912 Cluster: PREDICTED: similar to CG4200-PA;... 53 8e-06
UniRef50_UPI00004D6B5A Cluster: SH2B adapter protein 3 (Lymphocy... 53 8e-06
UniRef50_UPI0000660CE1 Cluster: Homolog of Brachydanio rerio "Ph... 53 8e-06
UniRef50_Q4SAX0 Cluster: Chromosome 3 SCAF14679, whole genome sh... 53 8e-06
UniRef50_O77132 Cluster: Non-receptor protein-tyrosine kinase CS... 53 8e-06
UniRef50_A7RR81 Cluster: Predicted protein; n=1; Nematostella ve... 53 8e-06
UniRef50_Q8N5H7 Cluster: SH2 domain-containing protein 3C; n=33;... 53 8e-06
UniRef50_UPI00015B62FA Cluster: PREDICTED: similar to ras gtpase... 53 1e-05
UniRef50_UPI0000E49CFC Cluster: PREDICTED: similar to Ras GTPase... 53 1e-05
UniRef50_UPI0000E1FA37 Cluster: PREDICTED: similar to signaling ... 53 1e-05
UniRef50_UPI00015A7910 Cluster: hypothetical protein LOC553596; ... 53 1e-05
UniRef50_UPI00006A1C31 Cluster: UPI00006A1C31 related cluster; n... 53 1e-05
UniRef50_UPI00006A1C30 Cluster: UPI00006A1C30 related cluster; n... 53 1e-05
UniRef50_A7S295 Cluster: Predicted protein; n=1; Nematostella ve... 53 1e-05
UniRef50_Q2I6J0 Cluster: Phosphatidylinositol-3,4,5-trisphosphat... 53 1e-05
UniRef50_Q92835 Cluster: Phosphatidylinositol-3,4,5-trisphosphat... 53 1e-05
UniRef50_UPI0000F318C3 Cluster: SH2B adapter protein 3 (Lymphocy... 52 1e-05
UniRef50_Q4SMI9 Cluster: Chromosome 18 SCAF14547, whole genome s... 52 1e-05
UniRef50_Q9UQQ2 Cluster: SH2B adapter protein 3; n=15; Tetrapoda... 52 1e-05
UniRef50_UPI00015A79D6 Cluster: hypothetical protein LOC550452; ... 52 2e-05
UniRef50_Q4V9Q1 Cluster: Zgc:109892; n=11; Euteleostomi|Rep: Zgc... 52 2e-05
UniRef50_Q4S516 Cluster: Chromosome 6 SCAF14737, whole genome sh... 52 2e-05
UniRef50_Q1LX18 Cluster: Novel protein similar to vertebrate src... 52 2e-05
UniRef50_Q6R1Y3 Cluster: Src family kinase; n=6; Fungi/Metazoa g... 52 2e-05
UniRef50_O97034 Cluster: PLC-gammaS; n=1; Ephydatia fluviatilis|... 52 2e-05
UniRef50_UPI000155BC71 Cluster: PREDICTED: similar to inositol p... 52 2e-05
UniRef50_UPI00003A9BD4 Cluster: PREDICTED: similar to SH2 domain... 52 2e-05
UniRef50_Q8AVM4 Cluster: Sh2d3c-prov protein; n=5; Euteleostomi|... 52 2e-05
UniRef50_Q4SYA1 Cluster: Chromosome undetermined SCAF12132, whol... 52 2e-05
UniRef50_A2IB48 Cluster: Phospholipase C gamma; n=5; Eumetazoa|R... 52 2e-05
UniRef50_P19174 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 52 2e-05
UniRef50_UPI0000F1FB23 Cluster: PREDICTED: similar to tyrosine p... 51 3e-05
UniRef50_UPI0000E811F8 Cluster: PREDICTED: similar to SH2D3C pro... 51 3e-05
UniRef50_Q4S131 Cluster: Chromosome 1 SCAF14770, whole genome sh... 51 3e-05
UniRef50_Q4RUN4 Cluster: Chromosome 12 SCAF14993, whole genome s... 51 3e-05
UniRef50_Q8IR23 Cluster: CG9209-PA, isoform A; n=6; Endopterygot... 51 3e-05
UniRef50_Q21055 Cluster: Protein tyrosine phosphatase protein 2;... 51 3e-05
UniRef50_O44235 Cluster: HrSH2 protein; n=1; Halocynthia roretzi... 51 3e-05
UniRef50_P50745 Cluster: SH2B adapter protein 3; n=3; Rattus nor... 51 3e-05
UniRef50_O14492 Cluster: SH2B adapter protein 2; n=7; Tetrapoda|... 51 3e-05
UniRef50_O43639 Cluster: Cytoplasmic protein NCK2; n=54; Euteleo... 51 3e-05
UniRef50_P08630 Cluster: Tyrosine-protein kinase Btk29A; n=10; E... 51 3e-05
UniRef50_P51813 Cluster: Cytoplasmic tyrosine-protein kinase BMX... 51 3e-05
UniRef50_UPI0000E48B80 Cluster: PREDICTED: hypothetical protein;... 51 4e-05
UniRef50_Q567F1 Cluster: Zgc:112091; n=2; Euteleostomi|Rep: Zgc:... 51 4e-05
UniRef50_Q17BH3 Cluster: Putative uncharacterized protein; n=1; ... 51 4e-05
UniRef50_UPI00015B5D64 Cluster: PREDICTED: similar to LD41184p; ... 50 6e-05
UniRef50_Q4T6N5 Cluster: Chromosome 9 SCAF8684, whole genome sho... 50 6e-05
UniRef50_Q9VXH3 Cluster: CG4200-PA; n=5; Drosophila|Rep: CG4200-... 50 6e-05
UniRef50_Q9VPU1 Cluster: CG3727-PB, isoform B; n=9; Endopterygot... 50 6e-05
UniRef50_Q9TYT3 Cluster: Putative uncharacterized protein; n=5; ... 50 6e-05
UniRef50_UPI0000ECA6D9 Cluster: SH2B adapter protein 3 (Lymphocy... 50 7e-05
UniRef50_Q5RJ36 Cluster: Novel protein similar to vertebrate lym... 50 7e-05
UniRef50_P07947 Cluster: Proto-oncogene tyrosine-protein kinase ... 50 7e-05
UniRef50_UPI000051A29D Cluster: PREDICTED: similar to SHC-adapto... 50 1e-04
UniRef50_Q5BWZ4 Cluster: SJCHGC04657 protein; n=1; Schistosoma j... 50 1e-04
UniRef50_UPI0000E478D2 Cluster: PREDICTED: similar to SH2/SH3 ad... 49 1e-04
UniRef50_UPI00015A3F46 Cluster: UPI00015A3F46 related cluster; n... 49 1e-04
UniRef50_Q6GP30 Cluster: MGC80721 protein; n=1; Xenopus laevis|R... 49 1e-04
UniRef50_Q5U3P8 Cluster: Zgc:101809; n=5; Danio rerio|Rep: Zgc:1... 49 1e-04
UniRef50_Q9NRF3 Cluster: SH2B adaptor protein 1; n=33; Mammalia|... 49 1e-04
UniRef50_UPI0000E4625F Cluster: PREDICTED: hypothetical protein;... 49 2e-04
UniRef50_UPI0000D8C686 Cluster: Breast cancer anti-estrogen resi... 49 2e-04
UniRef50_P52757 Cluster: Beta-chimaerin; n=13; Amniota|Rep: Beta... 49 2e-04
UniRef50_O75815 Cluster: Breast cancer anti-estrogen resistance ... 49 2e-04
UniRef50_UPI0000D57904 Cluster: PREDICTED: similar to CG9098-PA,... 48 2e-04
UniRef50_Q4S6Q5 Cluster: Chromosome undetermined SCAF14724, whol... 48 2e-04
UniRef50_Q4RUJ4 Cluster: Chromosome 1 SCAF14995, whole genome sh... 48 2e-04
UniRef50_A2RUZ0 Cluster: Zgc:158474 protein; n=4; Euteleostomi|R... 48 2e-04
UniRef50_Q7QGU0 Cluster: ENSANGP00000018199; n=1; Anopheles gamb... 48 2e-04
UniRef50_Q17AB7 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04
UniRef50_UPI0000F1FADE Cluster: PREDICTED: hypothetical protein;... 48 3e-04
UniRef50_UPI0000DB7594 Cluster: PREDICTED: similar to CG9098-PA,... 48 3e-04
UniRef50_UPI0000567EFA Cluster: UPI0000567EFA related cluster; n... 48 3e-04
UniRef50_Q17DJ2 Cluster: Signal transduction protein lnk-realted... 48 3e-04
UniRef50_Q13882 Cluster: Tyrosine-protein kinase 6; n=11; Mammal... 48 3e-04
UniRef50_Q9JID9 Cluster: SH2B adapter protein 2; n=16; Euteleost... 48 4e-04
UniRef50_Q13094 Cluster: Lymphocyte cytosolic protein 2; n=31; A... 48 4e-04
UniRef50_Q08881 Cluster: Tyrosine-protein kinase ITK/TSK; n=18; ... 48 4e-04
UniRef50_UPI0000E460CB Cluster: PREDICTED: similar to V-crk sarc... 47 5e-04
UniRef50_UPI000065CF8C Cluster: SH2 domain-containing protein 3C... 47 5e-04
UniRef50_Q910A2 Cluster: Spleen protein tyrosine kinase; n=2; Da... 47 5e-04
UniRef50_Q4SPM1 Cluster: Chromosome 16 SCAF14537, whole genome s... 47 5e-04
UniRef50_Q4S3B2 Cluster: Chromosome 4 SCAF14752, whole genome sh... 47 5e-04
UniRef50_Q1KL02 Cluster: Chimerin 2; n=3; Tetraodontidae|Rep: Ch... 47 5e-04
UniRef50_Q573B4 Cluster: Proto-oncogene tyrosine-protein kinase ... 47 5e-04
UniRef50_P43403 Cluster: Tyrosine-protein kinase ZAP-70; n=55; E... 47 5e-04
UniRef50_Q6PE32 Cluster: Zgc:65942; n=2; Danio rerio|Rep: Zgc:65... 47 7e-04
UniRef50_Q95PW9 Cluster: Temporarily assigned gene name protein ... 47 7e-04
UniRef50_Q9BRG2 Cluster: SH2 domain-containing protein 3A; n=11;... 47 7e-04
UniRef50_UPI0000F1F44E Cluster: PREDICTED: similar to Src-like-a... 46 9e-04
UniRef50_UPI0000E218D0 Cluster: PREDICTED: similar to SH2B adapt... 46 9e-04
UniRef50_UPI0000D5645D Cluster: PREDICTED: similar to CG17367-PB... 46 9e-04
UniRef50_UPI0000D55B96 Cluster: PREDICTED: similar to Tyrosine-p... 46 9e-04
UniRef50_UPI0000D554A0 Cluster: PREDICTED: similar to CG11146-PA... 46 9e-04
UniRef50_A2BDR6 Cluster: SH2 domain containing 3C; n=5; Danio re... 46 9e-04
UniRef50_Q9VMJ4 Cluster: CG9098-PA, isoform A; n=5; Diptera|Rep:... 46 9e-04
UniRef50_Q9NH62 Cluster: Tyrosine kinase 5; n=2; Schistosoma man... 46 9e-04
UniRef50_Q965N4 Cluster: Putative uncharacterized protein; n=3; ... 46 9e-04
UniRef50_Q06187 Cluster: Tyrosine-protein kinase BTK; n=54; Gnat... 46 9e-04
UniRef50_UPI0000E49A1C Cluster: PREDICTED: similar to Growth fac... 46 0.001
UniRef50_Q66I04 Cluster: Zgc:92124; n=1; Danio rerio|Rep: Zgc:92... 46 0.001
UniRef50_Q4RNX3 Cluster: Chromosome 10 SCAF15009, whole genome s... 46 0.001
UniRef50_Q9H3Y6 Cluster: Tyrosine-protein kinase Srms; n=17; Amn... 46 0.001
UniRef50_O14796 Cluster: SH2 domain-containing protein 1B; n=19;... 46 0.001
UniRef50_UPI00015B58E2 Cluster: PREDICTED: similar to signal tra... 46 0.002
UniRef50_Q4T2Z8 Cluster: Chromosome 18 SCAF10147, whole genome s... 46 0.002
UniRef50_Q4SBL7 Cluster: Chromosome 15 SCAF14667, whole genome s... 46 0.002
UniRef50_Q9Y1Y4 Cluster: Tyrosine-protein kinase; n=1; Ephydatia... 46 0.002
UniRef50_Q7Z7G1 Cluster: MIST; n=18; Eutheria|Rep: MIST - Homo s... 46 0.002
UniRef50_Q96JZ2 Cluster: Hematopoietic SH2 domain-containing pro... 46 0.002
UniRef50_UPI0000E47C6E Cluster: PREDICTED: similar to Grb2 adapt... 45 0.002
UniRef50_O60880-5 Cluster: Isoform E of O60880 ; n=5; Eutheria|R... 45 0.002
UniRef50_Q60I21 Cluster: TEC family protein tyrosine kinase; n=1... 45 0.002
UniRef50_Q70DV1 Cluster: Src tyrosine kinase; n=1; Schistosoma m... 45 0.002
UniRef50_P08631 Cluster: Tyrosine-protein kinase HCK; n=32; Eute... 45 0.002
UniRef50_Q4SKC0 Cluster: Chromosome 13 SCAF14566, whole genome s... 45 0.003
UniRef50_Q7K137 Cluster: LD10453p; n=4; Diptera|Rep: LD10453p - ... 44 0.004
UniRef50_A7RZ47 Cluster: Predicted protein; n=1; Nematostella ve... 44 0.004
UniRef50_UPI00015B5EF2 Cluster: PREDICTED: similar to ENSANGP000... 44 0.005
UniRef50_A2AQ87 Cluster: Novel protein (Possible orthologue of h... 44 0.006
UniRef50_Q13239 Cluster: SRC-like-adapter; n=26; Euteleostomi|Re... 44 0.006
UniRef50_UPI0000E4816C Cluster: PREDICTED: similar to phosphoino... 43 0.008
UniRef50_Q85476 Cluster: (recovered insertion mutant of B77) src... 43 0.008
UniRef50_Q4SII9 Cluster: Chromosome 5 SCAF14581, whole genome sh... 43 0.011
UniRef50_Q7M4L6 Cluster: Shb-like adapter protein, Shf; n=21; Am... 43 0.011
UniRef50_P51451 Cluster: Tyrosine-protein kinase BLK; n=5; Eutel... 43 0.011
UniRef50_UPI0000F2148D Cluster: PREDICTED: similar to signal tra... 42 0.015
UniRef50_UPI0000F1EB7D Cluster: PREDICTED: hypothetical protein;... 42 0.015
UniRef50_Q9BI25 Cluster: SHK1 protein; n=2; Dictyostelium discoi... 42 0.015
UniRef50_Q5BW49 Cluster: SJCHGC04880 protein; n=1; Schistosoma j... 42 0.015
UniRef50_UPI0000E48AB6 Cluster: PREDICTED: similar to B-cell lin... 42 0.019
UniRef50_Q3ZB94 Cluster: Zgc:113360; n=3; Clupeocephala|Rep: Zgc... 42 0.019
UniRef50_Q9V3C8 Cluster: CG3715-PA; n=7; Endopterygota|Rep: CG37... 42 0.019
UniRef50_Q6VYH9 Cluster: Hematopoietic SH2 domain-containing pro... 42 0.019
UniRef50_UPI0000D9EE2E Cluster: PREDICTED: similar to src homolo... 42 0.025
UniRef50_UPI00005A0859 Cluster: PREDICTED: similar to SH2 domain... 42 0.025
UniRef50_Q4RPN2 Cluster: Chromosome 12 SCAF15007, whole genome s... 42 0.025
UniRef50_Q1ED32 Cluster: Zgc:136231; n=1; Danio rerio|Rep: Zgc:1... 42 0.025
UniRef50_A7SJB4 Cluster: Predicted protein; n=1; Nematostella ve... 42 0.025
UniRef50_UPI000155BA92 Cluster: PREDICTED: similar to Fyn-relate... 41 0.034
UniRef50_UPI00006A0536 Cluster: Nck1-prov protein.; n=1; Xenopus... 41 0.034
UniRef50_Q08BY6 Cluster: Zgc:153964; n=3; Danio rerio|Rep: Zgc:1... 41 0.034
UniRef50_Q17PR7 Cluster: Putative uncharacterized protein; n=1; ... 41 0.034
UniRef50_A7RK55 Cluster: Predicted protein; n=1; Nematostella ve... 41 0.034
UniRef50_Q5SQS7 Cluster: Novel SH2 domain-containing protein; n=... 41 0.034
UniRef50_O00459 Cluster: Phosphatidylinositol 3-kinase regulator... 41 0.034
UniRef50_Q8T6F8 Cluster: SRC-1; n=3; Caenorhabditis|Rep: SRC-1 -... 41 0.045
UniRef50_Q7JVF1 Cluster: LP02169p; n=2; Sophophora|Rep: LP02169p... 41 0.045
UniRef50_O18683 Cluster: P60 protein; n=2; Sophophora|Rep: P60 p... 41 0.045
UniRef50_Q56A36 Cluster: Hematopoietic SH2 domain-containing pro... 41 0.045
UniRef50_UPI00015B496D Cluster: PREDICTED: similar to conserved ... 40 0.059
UniRef50_UPI0000DB713D Cluster: PREDICTED: similar to CG11146-PA... 40 0.059
UniRef50_UPI0000D56E93 Cluster: PREDICTED: similar to SH2 domain... 40 0.059
UniRef50_UPI00015A58A4 Cluster: UPI00015A58A4 related cluster; n... 40 0.059
UniRef50_Q7T0U4 Cluster: MGC68984 protein; n=2; Xenopus|Rep: MGC... 40 0.059
UniRef50_P42680 Cluster: Tyrosine-protein kinase Tec; n=86; Coel... 40 0.059
UniRef50_P00528 Cluster: Tyrosine-protein kinase Src64B; n=6; En... 40 0.059
UniRef50_Q96IW2 Cluster: SH2 domain-containing adapter protein D... 40 0.059
UniRef50_Q15464 Cluster: SH2 domain-containing adapter protein B... 40 0.059
UniRef50_Q9N597 Cluster: Phosphoinositide kinase adapter subunit... 40 0.078
UniRef50_O76978 Cluster: Tyrosine kinase; n=1; Sycon raphanus|Re... 40 0.078
UniRef50_Q9H6Q3 Cluster: Src-like-adapter 2; n=21; Euteleostomi|... 40 0.078
UniRef50_UPI0000D555ED Cluster: PREDICTED: similar to CG32406-PA... 40 0.10
UniRef50_Q9VYM1 Cluster: CG11146-PA; n=2; Coelomata|Rep: CG11146... 40 0.10
UniRef50_Q54U31 Cluster: SH2 domain-containing protein; n=1; Dic... 40 0.10
UniRef50_A0NEZ5 Cluster: ENSANGP00000031260; n=4; Culicidae|Rep:... 40 0.10
UniRef50_UPI0000F1E8DC Cluster: PREDICTED: similar to B-cell lin... 39 0.14
UniRef50_UPI000058412C Cluster: PREDICTED: hypothetical protein;... 39 0.14
UniRef50_Q4RL31 Cluster: Chromosome undetermined SCAF15024, whol... 39 0.18
UniRef50_Q5BXE5 Cluster: SJCHGC04002 protein; n=1; Schistosoma j... 39 0.18
UniRef50_Q23554 Cluster: Putative uncharacterized protein; n=1; ... 39 0.18
UniRef50_UPI00015B6424 Cluster: PREDICTED: similar to CG8146-PA;... 38 0.24
UniRef50_UPI0000DB7BD4 Cluster: PREDICTED: similar to Suppressor... 38 0.24
UniRef50_UPI0000447A3F Cluster: PREDICTED: similar to 1-phosphat... 38 0.24
UniRef50_Q4H2S4 Cluster: Suppressor of cytokine signaling; n=1; ... 38 0.24
UniRef50_O01325 Cluster: Putative uncharacterized protein; n=2; ... 38 0.24
UniRef50_UPI0000F2B3BE Cluster: PREDICTED: similar to Src-like-a... 38 0.31
UniRef50_UPI000058720B Cluster: PREDICTED: hypothetical protein;... 38 0.31
UniRef50_Q4SNX7 Cluster: Chromosome 15 SCAF14542, whole genome s... 38 0.31
UniRef50_Q4RNL0 Cluster: Chromosome 21 SCAF15012, whole genome s... 38 0.31
UniRef50_Q5T4P1 Cluster: Phosphoinositide-3-kinase, regulatory s... 38 0.31
UniRef50_Q9H788 Cluster: SH2 domain-containing protein 4A (Prote... 38 0.31
UniRef50_P18106 Cluster: Tyrosine-protein kinase Fps85D; n=12; E... 38 0.31
UniRef50_Q2MD52 Cluster: B-cell linker protein; n=7; Theria|Rep:... 38 0.41
UniRef50_UPI0000F1D8DB Cluster: PREDICTED: hypothetical protein;... 37 0.55
UniRef50_UPI0000D56397 Cluster: PREDICTED: similar to Tensin-1; ... 37 0.55
UniRef50_Q6NR09 Cluster: RE08107p; n=6; Diptera|Rep: RE08107p - ... 37 0.55
UniRef50_Q613B1 Cluster: Putative uncharacterized protein CBG164... 37 0.55
UniRef50_Q19726 Cluster: Putative uncharacterized protein kin-14... 37 0.55
UniRef50_Q16U30 Cluster: Putative uncharacterized protein; n=1; ... 37 0.55
UniRef50_A7T185 Cluster: Predicted protein; n=1; Nematostella ve... 37 0.55
UniRef50_UPI0000F2115F Cluster: PREDICTED: similar to tensin lik... 37 0.72
UniRef50_UPI0000F2002E Cluster: PREDICTED: hypothetical protein;... 37 0.72
UniRef50_UPI0000DB7727 Cluster: PREDICTED: similar to Tensin-1; ... 37 0.72
UniRef50_UPI0000DB7263 Cluster: PREDICTED: similar to Suppressor... 37 0.72
UniRef50_UPI0000567587 Cluster: PREDICTED: hypothetical protein;... 37 0.72
UniRef50_Q9VX18 Cluster: CG8146-PA; n=1; Drosophila melanogaster... 37 0.72
UniRef50_A6SPJ4 Cluster: Predicted protein; n=1; Botryotinia fuc... 37 0.72
UniRef50_Q29G65 Cluster: GA20849-PA; n=1; Drosophila pseudoobscu... 36 0.96
UniRef50_Q9HBL0 Cluster: Tensin-1; n=44; Eumetazoa|Rep: Tensin-1... 36 0.96
UniRef50_Q8WV28 Cluster: B-cell linker protein; n=24; Eutheria|R... 36 0.96
UniRef50_UPI0000F1F923 Cluster: PREDICTED: similar to SH2 domain... 36 1.3
UniRef50_UPI0000E48882 Cluster: PREDICTED: similar to tensin hom... 36 1.3
UniRef50_Q4SR72 Cluster: Chromosome 11 SCAF14528, whole genome s... 36 1.3
UniRef50_Q4RIA8 Cluster: Chromosome 8 SCAF15044, whole genome sh... 36 1.3
UniRef50_Q9XXE5 Cluster: Putative uncharacterized protein; n=1; ... 36 1.3
UniRef50_Q7QAK4 Cluster: ENSANGP00000020257; n=1; Anopheles gamb... 36 1.3
UniRef50_UPI00015B5375 Cluster: PREDICTED: similar to tensin; n=... 36 1.7
UniRef50_Q4SRP3 Cluster: Chromosome undetermined SCAF14505, whol... 36 1.7
UniRef50_Q9VRS2 Cluster: CG32406-PA; n=3; Sophophora|Rep: CG3240... 36 1.7
UniRef50_Q5DBN4 Cluster: SJCHGC05332 protein; n=1; Schistosoma j... 36 1.7
UniRef50_UPI0000519A8B Cluster: PREDICTED: similar to Phosphatid... 35 2.2
UniRef50_Q4SM94 Cluster: Chromosome 3 SCAF14553, whole genome sh... 35 2.2
UniRef50_Q95ZL4 Cluster: Temporarily assigned gene name protein ... 35 2.2
UniRef50_Q7Q6Z7 Cluster: ENSANGP00000017664; n=1; Anopheles gamb... 35 2.2
UniRef50_UPI0000F1E232 Cluster: PREDICTED: hypothetical protein;... 35 2.9
UniRef50_UPI0000E7F989 Cluster: PREDICTED: similar to 1-phosphat... 35 2.9
UniRef50_UPI00005A2FA4 Cluster: PREDICTED: similar to tensin-lik... 35 2.9
UniRef50_UPI0000503A18 Cluster: UPI0000503A18 related cluster; n... 35 2.9
UniRef50_UPI0000ECCD76 Cluster: tensin 3; n=1; Gallus gallus|Rep... 35 2.9
UniRef50_Q8WP81 Cluster: Putative uncharacterized protein; n=2; ... 35 2.9
UniRef50_Q5C0L2 Cluster: SJCHGC05893 protein; n=1; Schistosoma j... 35 2.9
UniRef50_Q5BYR6 Cluster: SJCHGC04559 protein; n=1; Schistosoma j... 35 2.9
UniRef50_A7SGW3 Cluster: Predicted protein; n=1; Nematostella ve... 35 2.9
UniRef50_Q7Z4S9 Cluster: SH2 domain-containing protein 6; n=7; E... 35 2.9
UniRef50_A6ND14 Cluster: Uncharacterized protein SH2D6; n=10; Eu... 35 2.9
UniRef50_Q04205 Cluster: Tensin; n=12; Euteleostomi|Rep: Tensin ... 35 2.9
UniRef50_Q68CZ2 Cluster: Tensin-3; n=33; Euteleostomi|Rep: Tensi... 35 2.9
UniRef50_UPI0000F1E3ED Cluster: PREDICTED: similar to cardiac mu... 34 3.9
UniRef50_UPI0000D559E9 Cluster: PREDICTED: similar to CG8146-PA;... 34 3.9
UniRef50_Q9NHC3 Cluster: Cell-corpse engulfment protein CED-2; n... 34 3.9
UniRef50_Q16IP4 Cluster: Phosphatidylinositol 3-kinase regulator... 34 3.9
UniRef50_UPI0000F2C764 Cluster: PREDICTED: similar to SH2-contai... 34 5.1
UniRef50_UPI0000E46C39 Cluster: PREDICTED: similar to ankyrin 2,... 34 5.1
UniRef50_UPI0000D5672D Cluster: PREDICTED: similar to CG3208-PA,... 34 5.1
UniRef50_UPI000049A54A Cluster: hypothetical protein 78.t00011; ... 34 5.1
UniRef50_UPI00015A6A53 Cluster: hypothetical protein LOC406311; ... 34 5.1
UniRef50_A3HPB9 Cluster: ProQ activator of osmoprotectant transp... 34 5.1
UniRef50_Q9W4A9 Cluster: CG3208-PA, isoform A; n=5; Diptera|Rep:... 34 5.1
UniRef50_A5K441 Cluster: Putative uncharacterized protein; n=2; ... 34 5.1
UniRef50_P52735 Cluster: Protein vav-2; n=28; Euteleostomi|Rep: ... 34 5.1
UniRef50_UPI0000F1FE6B Cluster: PREDICTED: hypothetical protein;... 33 6.8
UniRef50_Q6PBV3 Cluster: Zgc:73230; n=2; Danio rerio|Rep: Zgc:73... 33 6.8
UniRef50_Q4RUJ0 Cluster: Chromosome 1 SCAF14995, whole genome sh... 33 6.8
UniRef50_Q380D8 Cluster: ENSANGP00000027059; n=2; Culicidae|Rep:... 33 6.8
UniRef50_Q9UKW4 Cluster: Protein vav-3; n=96; Euteleostomi|Rep: ... 33 6.8
UniRef50_UPI00006A214E Cluster: SH2 domain-containing adapter pr... 33 8.9
UniRef50_UPI00006A0ADF Cluster: Tensin-1.; n=5; Xenopus tropical... 33 8.9
UniRef50_UPI000069FBD8 Cluster: tensin like C1 domain containing... 33 8.9
UniRef50_UPI000069FBD7 Cluster: tensin like C1 domain containing... 33 8.9
UniRef50_UPI000069FBD6 Cluster: tensin like C1 domain containing... 33 8.9
UniRef50_O04521 Cluster: F20P5.3 protein; n=4; Arabidopsis thali... 33 8.9
UniRef50_Q4JSB7 Cluster: Tensin; n=3; Culicidae|Rep: Tensin - An... 33 8.9
UniRef50_O01927 Cluster: Putative uncharacterized protein; n=2; ... 33 8.9
UniRef50_Q63HR2 Cluster: Tensin-like C1 domain-containing phosph... 33 8.9
>UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein
tyrosine kinase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to protein tyrosine kinase - Nasonia
vitripennis
Length = 739
Score = 128 bits (309), Expect = 2e-28
Identities = 80/187 (42%), Positives = 109/187 (58%), Gaps = 3/187 (1%)
Frame = +1
Query: 274 MNREDNVNWFHGKISRESAEKLLKEEGED-GVFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
M ED+V WFHG +SRE AE LL E+G D G FLVRES++S GDYVLSVLH G+V HYQI
Sbjct: 1 MGTEDDVCWFHGNLSREDAESLLLEDGRDNGTFLVRESSSSLGDYVLSVLHDGEVAHYQI 60
Query: 451 RRHGEDAFFSIEEHTTVHG--WILLYNITVVIQMDLLLGCPLSVKENHHRMSRGHREQQI 624
R+HGEDAFFSI++ TT+HG ++ Y ++ +L P+ H R R +
Sbjct: 61 RKHGEDAFFSIDDETTIHGLETLIEYYQKENDRLVTILQTPIRGLPPPHDTRRHGRMNLL 120
Query: 625 YCTEQRKRVISTWCRSYWASGLPESRRQETRTVRTAVHIAARAGRDXILAELHRXAAPLS 804
+ +K T G S + + +TAVH+AA G D IL++L + A ++
Sbjct: 121 HRATIQKNY--TIVSELLKCGY-RSLDAKNQLGQTAVHLAAIDGADEILSKLIQNNASVN 177
Query: 805 TFRDSFG 825
RD+ G
Sbjct: 178 C-RDTAG 183
Score = 46.8 bits (106), Expect = 7e-04
Identities = 24/63 (38%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
Frame = +1
Query: 271 RMNREDNVNWFHGKISRESAEKLLKEEGE-DGVFLVRESNTSPGDYVLSVLHQGQVVHYQ 447
R +E +W+HG + R A LL + G+ DG FLVR S G VL+V++ H+Q
Sbjct: 274 RPTKEKASDWYHGTLDRMEAINLLHKNGDLDGSFLVRLSERHDGIRVLTVMYNKTPYHFQ 333
Query: 448 IRR 456
I++
Sbjct: 334 IQK 336
>UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2;
Culicidae|Rep: Tyrosine-protein kinase shark - Aedes
aegypti (Yellowfever mosquito)
Length = 939
Score = 126 bits (305), Expect = 5e-28
Identities = 54/78 (69%), Positives = 69/78 (88%)
Frame = +1
Query: 274 MNREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIR 453
MNRE+N+ WFHGKISRE AE++L++EG +GVF+VRES +S GD+VLSVL Q +VVHYQIR
Sbjct: 1 MNREENLCWFHGKISRERAEEILRQEGGNGVFMVRESTSSEGDFVLSVLFQDEVVHYQIR 60
Query: 454 RHGEDAFFSIEEHTTVHG 507
RHG+DAFFSI++H +HG
Sbjct: 61 RHGDDAFFSIDDHMPIHG 78
Score = 79.4 bits (187), Expect = 1e-13
Identities = 33/57 (57%), Positives = 44/57 (77%)
Frame = +3
Query: 507 MDTLIQHYRSDSNGLVTRLSIVCKGEPPPHESRTQGTTNLLHRATEAGHFNVVSKLL 677
+D+LI+HYR SNGLVTRL VC+ PPPH+ R+ G NLLHRATE ++ VVS+++
Sbjct: 79 LDSLIEHYRESSNGLVTRLQTVCQSGPPPHDVRSHGKENLLHRATENSNYTVVSEMI 135
>UniRef50_UPI0000D57699 Cluster: PREDICTED: similar to CG18247-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG18247-PA - Tribolium castaneum
Length = 725
Score = 121 bits (292), Expect = 2e-26
Identities = 79/191 (41%), Positives = 112/191 (58%), Gaps = 7/191 (3%)
Frame = +1
Query: 274 MNREDNVNWFHGKISRESAEKLLKEEGE-DGVFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
M ++++ W+HGK+SRE+ E LLKEEG DG FLVRESN+S GD+VLSVLH +V H+QI
Sbjct: 1 MCTDEDIFWYHGKLSREATENLLKEEGRPDGSFLVRESNSSTGDFVLSVLHNNEVSHFQI 60
Query: 451 RRHGEDAFFSIEEHTTVHGWILLYNITVVIQMDLLLGCPLSVK---ENHHRMSRGHREQQ 621
RRH EDAFFSI+E+T +HG L V + L G L+V + SR H
Sbjct: 61 RRHSEDAFFSIDENTKIHGLESLIEHYVNTKGILSEGLSLTVPVKGDAPPDYSRRHGRTN 120
Query: 622 IY---CTEQRKRVISTWCRSYWASGLPESRRQETRTVRTAVHIAARAGRDXILAELHRXA 792
+ E +V+S ++ + E++ Q +TAVH+A+ G+D IL +L
Sbjct: 121 LLHRATKEGNYKVVSEVLKTGYRH---EAKNQNG---QTAVHLASMNGKDDILRKLIDYG 174
Query: 793 APLSTFRDSFG 825
A ++ RD+ G
Sbjct: 175 ASVN-LRDTAG 184
Score = 39.9 bits (89), Expect = 0.078
Identities = 20/60 (33%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKE-EGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAF 474
W+HG + R AE +K+ +DG FLVR S+ + + VL+++++ +Y IR+ + F
Sbjct: 286 WYHGTLDRHEAETTIKQFSTKDGTFLVRWSDRNK-ERVLTLINESLFYNYIIRKQDDYLF 344
>UniRef50_Q24145 Cluster: Tyrosine-protein kinase shark; n=2;
Sophophora|Rep: Tyrosine-protein kinase shark -
Drosophila melanogaster (Fruit fly)
Length = 939
Score = 100 bits (240), Expect = 4e-20
Identities = 46/74 (62%), Positives = 63/74 (85%), Gaps = 2/74 (2%)
Frame = +1
Query: 274 MNRE-DNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
M+R+ D + W+HG +SRE+A++LLK+ EDG FLVRES+T+ GD+VLS+L QG+V HYQ+
Sbjct: 1 MSRDSDPMKWYHGNLSREAADELLKQGYEDGTFLVRESSTAAGDFVLSLLCQGEVCHYQV 60
Query: 451 RRH-GEDAFFSIEE 489
RRH GEDAFFSI++
Sbjct: 61 RRHGGEDAFFSIDD 74
Score = 60.5 bits (140), Expect = 5e-08
Identities = 31/73 (42%), Positives = 44/73 (60%)
Frame = +3
Query: 507 MDTLIQHYRSDSNGLVTRLSIVCKGEPPPHESRTQGTTNLLHRATEAGHFNVVSKLLGKR 686
+DTL+ +Y+ +NGL T+L++ + PPH +R+ G TNLLHRAT VV +LL K
Sbjct: 84 LDTLVDYYQQAANGLPTKLTVPLIRDLPPHNTRSHGVTNLLHRATSKNESKVVFELL-KC 142
Query: 687 ATGVATPRNQDXQ 725
+NQD Q
Sbjct: 143 GYRNFDAKNQDGQ 155
>UniRef50_P03949 Cluster: Tyrosine-protein kinase abl-1; n=5;
Caenorhabditis|Rep: Tyrosine-protein kinase abl-1 -
Caenorhabditis elegans
Length = 1224
Score = 69.3 bits (162), Expect = 1e-10
Identities = 34/78 (43%), Positives = 45/78 (57%)
Frame = +1
Query: 256 NSFLLRMNREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQV 435
++F+ N D W+HGKISR +E +L G G FLVRES TS G Y +SV H G+V
Sbjct: 180 SNFIAPYNSLDKYTWYHGKISRSDSEAILGS-GITGSFLVRESETSIGQYTISVRHDGRV 238
Query: 436 VHYQIRRHGEDAFFSIEE 489
HY+I + F +E
Sbjct: 239 FHYRINVDNTEKMFITQE 256
>UniRef50_P53356 Cluster: Tyrosine-protein kinase HTK16; n=1; Hydra
vulgaris|Rep: Tyrosine-protein kinase HTK16 - Hydra
attenuata (Hydra) (Hydra vulgaris)
Length = 757
Score = 68.9 bits (161), Expect = 1e-10
Identities = 35/86 (40%), Positives = 55/86 (63%), Gaps = 1/86 (1%)
Frame = +1
Query: 286 DNVNWFHGKISRESA-EKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHG 462
D + W+HGKI+RE A + LL++ G DG FL+R+ +P DYVLS++ + Q++H+QI G
Sbjct: 6 DALLWYHGKITREVAVQVLLRKGGRDGFFLIRDCGNAPEDYVLSMMFRSQILHFQINCLG 65
Query: 463 EDAFFSIEEHTTVHGWILLYNITVVI 540
++ FSI+ G +L + VI
Sbjct: 66 DNK-FSIDNGPIFQGLDMLISYYKVI 90
Score = 41.1 bits (92), Expect = 0.034
Identities = 21/65 (32%), Positives = 36/65 (55%), Gaps = 1/65 (1%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEG-EDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAF 474
W H + R A +L+ DG FL+R S G YVL+++++ + H+QI+ D +
Sbjct: 287 WLHQNLDRNGALIILQNASMADGSFLIRSSIKCHGYYVLTLVYEKKTYHFQIKSRA-DRW 345
Query: 475 FSIEE 489
F I++
Sbjct: 346 FYIDD 350
>UniRef50_UPI0000E48523 Cluster: PREDICTED: similar to
protein-tyrosine kinase; n=3; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to protein-tyrosine
kinase - Strongylocentrotus purpuratus
Length = 837
Score = 68.5 bits (160), Expect = 2e-10
Identities = 35/91 (38%), Positives = 52/91 (57%), Gaps = 1/91 (1%)
Frame = +1
Query: 256 NSFLLRMNREDNVNWFHGKISRESAEKLLKEEGE-DGVFLVRESNTSPGDYVLSVLHQGQ 432
N E ++ WFHG+I+R++A +LK G +G FLVRES + GDYV+S++H G
Sbjct: 62 NDVAAAKEEEKDLLWFHGRITRDTAVHVLKGNGSGEGTFLVRESTSRSGDYVVSIMHNGL 121
Query: 433 VVHYQIRRHGEDAFFSIEEHTTVHGWILLYN 525
H+QI+ G D ++ I+ G L N
Sbjct: 122 PQHFQIQCMG-DFYYKIDNGPLFQGLDQLIN 151
Score = 51.2 bits (117), Expect = 3e-05
Identities = 24/45 (53%), Positives = 29/45 (64%)
Frame = +3
Query: 507 MDTLIQHYRSDSNGLVTRLSIVCKGEPPPHESRTQGTTNLLHRAT 641
+D LI +YR SNGL T+L++ C G PP SR G T LHRAT
Sbjct: 146 LDQLINYYRMGSNGLPTKLTVFCNGRIPPPCSRRFGRTTPLHRAT 190
Score = 45.2 bits (102), Expect = 0.002
Identities = 26/87 (29%), Positives = 45/87 (51%), Gaps = 1/87 (1%)
Frame = +1
Query: 217 HDNNHDVIHIT*ENSFLLRMNREDNVNWFHGKISRESA-EKLLKEEGEDGVFLVRESNTS 393
++++H V+++ S ++ R WFHG + R+ A E + K +DG FL+R S
Sbjct: 327 YEHSHVVMYL---KSCKPKVPRLQGKPWFHGSMDRKKALESIQKHGAKDGQFLLRSSANK 383
Query: 394 PGDYVLSVLHQGQVVHYQIRRHGEDAF 474
P VLS+ G V +++I E +
Sbjct: 384 PDTMVLSMAANGTVFNFEINTKMESFY 410
>UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monosiga
ovata|Rep: Protein tyrosine kinase CSK - Monosiga ovata
Length = 468
Score = 68.5 bits (160), Expect = 2e-10
Identities = 37/64 (57%), Positives = 42/64 (65%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAFF 477
WFHGKISRE AE LL EDG+FLVRES PGDY L V Q QV HY R G++
Sbjct: 101 WFHGKISRELAESLLMPR-EDGLFLVRESAHFPGDYTLCVCFQDQVDHY--RMQGKNGKL 157
Query: 478 SIEE 489
+I+E
Sbjct: 158 TIDE 161
>UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 485
Score = 66.5 bits (155), Expect = 8e-10
Identities = 31/54 (57%), Positives = 40/54 (74%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRH 459
WFHG+ISRE AEKLL ++G FLVRES PGDY L V + G+V +Y++RR+
Sbjct: 109 WFHGRISREDAEKLLTPP-KNGRFLVRESQNYPGDYTLCVSYDGRVENYRVRRN 161
>UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2;
Culicidae|Rep: Tyrosine-protein kinase - Aedes aegypti
(Yellowfever mosquito)
Length = 747
Score = 66.5 bits (155), Expect = 8e-10
Identities = 31/52 (59%), Positives = 36/52 (69%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIR 453
WFHG+I RE AE LLK EDG+FLVRES PGDY L V +V HY+I+
Sbjct: 378 WFHGRIKREEAENLLKPR-EDGLFLVRESTNFPGDYTLCVCFNEKVEHYRIK 428
>UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21;
Deuterostomia|Rep: Tyrosine-protein kinase CSK - Homo
sapiens (Human)
Length = 450
Score = 66.5 bits (155), Expect = 8e-10
Identities = 35/64 (54%), Positives = 41/64 (64%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAFF 477
WFHGKI+RE AE+LL E G+FLVRES PGDY L V G+V HY+I H
Sbjct: 82 WFHGKITREQAERLLYPP-ETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASK--L 138
Query: 478 SIEE 489
SI+E
Sbjct: 139 SIDE 142
>UniRef50_UPI0000E497E3 Cluster: PREDICTED: similar to
protein-tyrosine phosphatase; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to protein-tyrosine
phosphatase - Strongylocentrotus purpuratus
Length = 533
Score = 66.1 bits (154), Expect = 1e-09
Identities = 29/55 (52%), Positives = 40/55 (72%)
Frame = +1
Query: 289 NVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIR 453
N WFHG I+ + AEK L ++G++G +LVRES++ PGDYVLSV + +V H IR
Sbjct: 109 NERWFHGHITGKEAEKSLVDKGKNGSYLVRESHSKPGDYVLSVRTEDKVTHVMIR 163
Score = 60.5 bits (140), Expect = 5e-08
Identities = 29/62 (46%), Positives = 38/62 (61%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAFF 477
WFH IS AE+LL G DG FL R S ++PGD+ LSV G+V H +I+ G+ FF
Sbjct: 6 WFHPNISGMEAEQLLLNNGFDGCFLCRPSKSNPGDFTLSVRRNGEVTHIKIQNTGD--FF 63
Query: 478 SI 483
+
Sbjct: 64 DL 65
>UniRef50_P29349 Cluster: Tyrosine-protein phosphatase corkscrew;
n=15; Eumetazoa|Rep: Tyrosine-protein phosphatase
corkscrew - Drosophila melanogaster (Fruit fly)
Length = 845
Score = 66.1 bits (154), Expect = 1e-09
Identities = 29/52 (55%), Positives = 37/52 (71%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIR 453
WFHG +S + AEKL+ E G++G FLVRES + PGD+VLSV +V H IR
Sbjct: 111 WFHGNLSGKEAEKLILERGKNGSFLVRESQSKPGDFVLSVRTDDKVTHVMIR 162
Score = 59.7 bits (138), Expect = 9e-08
Identities = 29/62 (46%), Positives = 41/62 (66%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAFF 477
WFH IS AEKLL+E+G DG FL R S+++PG + LSV +V H +I+ +G+ FF
Sbjct: 6 WFHPTISGIEAEKLLQEQGFDGSFLARLSSSNPGAFTLSVRRGNEVTHIKIQNNGD--FF 63
Query: 478 SI 483
+
Sbjct: 64 DL 65
>UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP09923p
- Drosophila melanogaster (Fruit fly)
Length = 847
Score = 65.3 bits (152), Expect = 2e-09
Identities = 29/52 (55%), Positives = 37/52 (71%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIR 453
WFHG I+R+ AE LL+ EDG+FLVRES PGDY L V Q +V HY+++
Sbjct: 479 WFHGSITRDEAEHLLQPR-EDGLFLVRESTNFPGDYTLCVCFQSKVEHYRVK 529
>UniRef50_UPI000058445F Cluster: PREDICTED: similar to SH2/SH3
adaptor protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to SH2/SH3 adaptor protein -
Strongylocentrotus purpuratus
Length = 389
Score = 64.9 bits (151), Expect = 2e-09
Identities = 26/54 (48%), Positives = 40/54 (74%)
Frame = +1
Query: 295 NWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
+WFHG+I+R+ +EK+L GE G+FL+RES T PGD+ +SV +V H+++ R
Sbjct: 290 DWFHGRITRQDSEKILGCPGESGLFLIRESETMPGDFAVSVKAPERVKHFKVTR 343
>UniRef50_Q4SIP6 Cluster: Chromosome 21 SCAF14577, whole genome
shotgun sequence; n=4; Tetraodontidae|Rep: Chromosome 21
SCAF14577, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 608
Score = 64.9 bits (151), Expect = 2e-09
Identities = 29/70 (41%), Positives = 50/70 (71%), Gaps = 3/70 (4%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGE-DGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGED-- 468
WFHG+I RE A K++ ++G+ DG+FL+R+S ++P +VL++ H ++ H+QI ED
Sbjct: 507 WFHGRIVREEAHKMIIQQGQVDGLFLLRDSQSNPRAFVLTLCHHQKIKHFQILPCEEDGQ 566
Query: 469 AFFSIEEHTT 498
FFS+++ +T
Sbjct: 567 VFFSLDDGST 576
>UniRef50_A2AAH7 Cluster: Growth factor receptor bound protein 2;
n=3; Mammalia|Rep: Growth factor receptor bound protein
2 - Mus musculus (Mouse)
Length = 203
Score = 64.5 bits (150), Expect = 3e-09
Identities = 27/60 (45%), Positives = 39/60 (65%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAFF 477
WF GKI R AE++L ++ DG FL+RES ++PGD+ LSV V H+++ R G +F
Sbjct: 60 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119
>UniRef50_P62993 Cluster: Growth factor receptor-bound protein 2;
n=26; Euteleostomi|Rep: Growth factor receptor-bound
protein 2 - Homo sapiens (Human)
Length = 217
Score = 64.5 bits (150), Expect = 3e-09
Identities = 27/60 (45%), Positives = 39/60 (65%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAFF 477
WF GKI R AE++L ++ DG FL+RES ++PGD+ LSV V H+++ R G +F
Sbjct: 60 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119
>UniRef50_Q98TP5 Cluster: C-Src protein-tyrosine kinase; n=5;
Euteleostomi|Rep: C-Src protein-tyrosine kinase -
Platichthys flesus (European flounder)
Length = 120
Score = 63.7 bits (148), Expect = 6e-09
Identities = 33/65 (50%), Positives = 39/65 (60%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAFF 477
WFHGKI+R AE+LL E G+FLVRES PGDY L V G+V HY+I H
Sbjct: 18 WFHGKITRNQAEQLLCPP-ETGLFLVRESTNFPGDYTLCVSCDGKVEHYRIIYHNGKLTI 76
Query: 478 SIEEH 492
EE+
Sbjct: 77 DEEEY 81
>UniRef50_Q9Y1Y2 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 743
Score = 63.7 bits (148), Expect = 6e-09
Identities = 32/77 (41%), Positives = 47/77 (61%), Gaps = 3/77 (3%)
Frame = +1
Query: 286 DNVNWFHGKISRESAEKLLKE---EGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
D W+HGKI+RE+A L+ + +G+FLVRES +PG YVL++ +G V +QI
Sbjct: 6 DAERWYHGKITRENAAHLVSQGPITRREGLFLVRESTRTPGSYVLTLWAKGNVQQFQIMG 65
Query: 457 HGEDAFFSIEEHTTVHG 507
HGE +FS++ G
Sbjct: 66 HGE-GWFSVDNGPLFQG 81
Score = 45.6 bits (103), Expect = 0.002
Identities = 22/61 (36%), Positives = 37/61 (60%), Gaps = 1/61 (1%)
Frame = +1
Query: 271 RMNREDNVNWFHGKISRESAEKLLKEEG-EDGVFLVRESNTSPGDYVLSVLHQGQVVHYQ 447
RMN D + H I R +A + LK++G DG FL+R ++ PG Y L+++++ HY+
Sbjct: 286 RMNTND---FLHKAIDRNNAVETLKQKGLSDGSFLIRPNSRKPGSYALTLVYKQTPYHYE 342
Query: 448 I 450
+
Sbjct: 343 V 343
Score = 35.5 bits (78), Expect = 1.7
Identities = 20/62 (32%), Positives = 31/62 (50%)
Frame = +3
Query: 507 MDTLIQHYRSDSNGLVTRLSIVCKGEPPPHESRTQGTTNLLHRATEAGHFNVVSKLLGKR 686
+D LI HY+ +GL +L+ G PPP +R + T LH+A V +L +
Sbjct: 82 LDELIHHYQLKPDGLPVQLNDYVIGNPPPPGARKRTETE-LHKAVATRDLAAVLSILSQP 140
Query: 687 AT 692
A+
Sbjct: 141 AS 142
>UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosine
kinase CG4032-PA; n=1; Apis mellifera|Rep: PREDICTED:
similar to Abl tyrosine kinase CG4032-PA - Apis
mellifera
Length = 1439
Score = 63.3 bits (147), Expect = 7e-09
Identities = 30/78 (38%), Positives = 48/78 (61%)
Frame = +1
Query: 256 NSFLLRMNREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQV 435
++++ +N + +W+HG+I R +AE LL G +G FLVRES +SPG +S+ ++G+V
Sbjct: 160 SNYVTPVNSLEKHSWYHGRICRNAAEYLLSS-GINGSFLVRESESSPGQRSISLRYEGRV 218
Query: 436 VHYQIRRHGEDAFFSIEE 489
HY+I E F E
Sbjct: 219 YHYRINEDSEGKMFVTTE 236
>UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to
proto-oncogene tyrosine-protein kinase abl1; n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to
proto-oncogene tyrosine-protein kinase abl1 - Nasonia
vitripennis
Length = 1522
Score = 62.9 bits (146), Expect = 1e-08
Identities = 29/78 (37%), Positives = 49/78 (62%)
Frame = +1
Query: 256 NSFLLRMNREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQV 435
++++ +N + +W+HG+ISR +AE LL G +G FLVRES +SPG +S+ ++G+V
Sbjct: 161 SNYVTPVNSLEKHSWYHGRISRNAAEYLLSS-GINGSFLVRESESSPGQRSISLRYEGRV 219
Query: 436 VHYQIRRHGEDAFFSIEE 489
HY+I + + E
Sbjct: 220 YHYRINEDSDGKMYVTTE 237
>UniRef50_A7SCW1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 275
Score = 62.9 bits (146), Expect = 1e-08
Identities = 30/63 (47%), Positives = 40/63 (63%)
Frame = +1
Query: 274 MNREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIR 453
M+R+D + W+HG + R E +L + GV+LVR+S T PGDYVLSV G+V HY I
Sbjct: 1 MSRKDQLPWYHGVLKRVETEGILNGK-PPGVWLVRDSTTIPGDYVLSVSESGKVSHYIIN 59
Query: 454 RHG 462
G
Sbjct: 60 NKG 62
>UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1;
n=11; Metazoa|Rep: Tyrosine-protein kinase isoform SRK1
- Spongilla lacustris (Freshwater sponge)
Length = 505
Score = 62.9 bits (146), Expect = 1e-08
Identities = 31/71 (43%), Positives = 43/71 (60%), Gaps = 1/71 (1%)
Frame = +1
Query: 286 DNVNWFHGKISRESAEKLLKEE-GEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHG 462
D WF GKI R AEK+L + + G FL+R+S T+PGD+ LSV Q +V HY++RR
Sbjct: 118 DAEEWFLGKIKRVEAEKMLNQSFNQVGSFLIRDSETTPGDFSLSVKDQDRVRHYRVRRLE 177
Query: 463 EDAFFSIEEHT 495
+ + F T
Sbjct: 178 DGSLFVTRRST 188
>UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5;
Eumetazoa|Rep: Tyrosine-protein kinase Abl - Drosophila
melanogaster (Fruit fly)
Length = 1620
Score = 62.9 bits (146), Expect = 1e-08
Identities = 30/78 (38%), Positives = 49/78 (62%)
Frame = +1
Query: 256 NSFLLRMNREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQV 435
++++ +N + +W+HG ISR +AE LL G +G FLVRES +SPG +S+ ++G+V
Sbjct: 240 SNYVTPLNSLEKHSWYHGPISRNAAEYLLSS-GINGSFLVRESESSPGQRSISLRYEGRV 298
Query: 436 VHYQIRRHGEDAFFSIEE 489
HY+I + F +E
Sbjct: 299 YHYRISEDPDGKVFVTQE 316
>UniRef50_Q13322-2 Cluster: Isoform 1 of Q13322 ; n=5;
Homo/Pan/Gorilla group|Rep: Isoform 1 of Q13322 - Homo
sapiens (Human)
Length = 548
Score = 62.5 bits (145), Expect = 1e-08
Identities = 27/71 (38%), Positives = 51/71 (71%), Gaps = 3/71 (4%)
Frame = +1
Query: 295 NWFHGKISRESAEKLLKEEG-EDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGED- 468
+WFHG+ISRE + +++K++G DG+FL+R+S ++P +VL++ H ++ ++QI +D
Sbjct: 446 HWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKNFQILPCEDDG 505
Query: 469 -AFFSIEEHTT 498
FFS+++ T
Sbjct: 506 QTFFSLDDGNT 516
>UniRef50_O88890 Cluster: SH2 domain-containing protein 1A; n=8;
Eutheria|Rep: SH2 domain-containing protein 1A - Mus
musculus (Mouse)
Length = 126
Score = 62.5 bits (145), Expect = 1e-08
Identities = 33/73 (45%), Positives = 45/73 (61%)
Frame = +1
Query: 286 DNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGE 465
D V +HGKISRE+ EKLL G DG +L+R+S + PG Y L VL+QG + Y++ + E
Sbjct: 2 DAVTVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYQGYIYTYRVSQ-TE 60
Query: 466 DAFFSIEEHTTVH 504
+S E VH
Sbjct: 61 TGSWSAETAPGVH 73
>UniRef50_Q13322 Cluster: Growth factor receptor-bound protein 10;
n=113; Euteleostomi|Rep: Growth factor receptor-bound
protein 10 - Homo sapiens (Human)
Length = 594
Score = 62.5 bits (145), Expect = 1e-08
Identities = 27/71 (38%), Positives = 51/71 (71%), Gaps = 3/71 (4%)
Frame = +1
Query: 295 NWFHGKISRESAEKLLKEEG-EDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGED- 468
+WFHG+ISRE + +++K++G DG+FL+R+S ++P +VL++ H ++ ++QI +D
Sbjct: 492 HWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKNFQILPCEDDG 551
Query: 469 -AFFSIEEHTT 498
FFS+++ T
Sbjct: 552 QTFFSLDDGNT 562
>UniRef50_UPI0000F201D0 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 475
Score = 62.1 bits (144), Expect = 2e-08
Identities = 30/65 (46%), Positives = 47/65 (72%), Gaps = 2/65 (3%)
Frame = +1
Query: 268 LRMNRED--NVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVH 441
L+++ ED + W+HG++ RE+ E+LL G DG FLVR+S+TS GDYVL+ + + Q +H
Sbjct: 15 LKLSTEDLRSQAWYHGQLQREATEQLL---GRDGEFLVRDSSTSAGDYVLTCMWKNQPMH 71
Query: 442 YQIRR 456
++I R
Sbjct: 72 FKIIR 76
>UniRef50_Q7YZX2 Cluster: Bruton's tyrosine kinase-like protein;
n=1; Suberites domuncula|Rep: Bruton's tyrosine
kinase-like protein - Suberites domuncula (Sponge)
Length = 700
Score = 61.7 bits (143), Expect = 2e-08
Identities = 29/69 (42%), Positives = 42/69 (60%)
Frame = +1
Query: 286 DNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGE 465
D+ WF ++SR AE +LK EG +G F+VR S+ Y LS+ H+GQV HY I+
Sbjct: 314 DSEEWFFPQLSRTRAENILKGEGREGGFVVRNSSRE-NMYTLSICHEGQVRHYHIKLDES 372
Query: 466 DAFFSIEEH 492
+ +F E+H
Sbjct: 373 NKYFISEKH 381
>UniRef50_Q9Y1X9 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 573
Score = 61.3 bits (142), Expect = 3e-08
Identities = 30/55 (54%), Positives = 38/55 (69%), Gaps = 1/55 (1%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGE-DGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRH 459
W+HG+ISR AE+LL G G FLVR+S T+ G+YVLS+ QG+ HY I RH
Sbjct: 9 WYHGRISRLDAEQLLDNFGRLSGSFLVRDSLTTTGEYVLSLSFQGKKYHYIISRH 63
Score = 46.0 bits (104), Expect = 0.001
Identities = 23/50 (46%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEG-EDGVFLVRESNTSPGDYVLSVLHQGQVVHY 444
WFHG ISRE +E+ +K G DG+FLVRE T + L V + + HY
Sbjct: 163 WFHGAISREESEQRMKAFGLRDGLFLVRE-RTEVNSFALCVAVKNDIYHY 211
>UniRef50_A2RQD7 Cluster: Bcr-abl1 e19a2 chimeric protein; n=2; Homo
sapiens|Rep: Bcr-abl1 e19a2 chimeric protein - Homo
sapiens (Human)
Length = 498
Score = 61.3 bits (142), Expect = 3e-08
Identities = 28/78 (35%), Positives = 48/78 (61%)
Frame = +1
Query: 256 NSFLLRMNREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQV 435
++++ +N + +W+HG +SR +AE LL G +G FLVRES +SPG +S+ ++G+V
Sbjct: 365 SNYITPVNSLEKHSWYHGPVSRNAAEHLLSS-GINGSFLVRESESSPGQRSISLRYEGRV 423
Query: 436 VHYQIRRHGEDAFFSIEE 489
HY+I + + E
Sbjct: 424 YHYRINTASDGKLYVSSE 441
>UniRef50_Q13588 Cluster: GRB2-related adapter protein; n=21;
Bilateria|Rep: GRB2-related adapter protein - Homo
sapiens (Human)
Length = 217
Score = 61.3 bits (142), Expect = 3e-08
Identities = 26/64 (40%), Positives = 42/64 (65%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAFF 477
W+ G+ISR+ AE++L + G FL+RES +SPG++ +SV + QV H+++ R +F
Sbjct: 60 WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYF 119
Query: 478 SIEE 489
EE
Sbjct: 120 LWEE 123
>UniRef50_Q9BL77 Cluster: C-terminal src kinase protein 1; n=2;
Caenorhabditis|Rep: C-terminal src kinase protein 1 -
Caenorhabditis elegans
Length = 539
Score = 60.9 bits (141), Expect = 4e-08
Identities = 28/53 (52%), Positives = 36/53 (67%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
WFH ISRE+ EKLL+ + DG FLVRES PGD+ L + G+V HY+I +
Sbjct: 151 WFHSMISRENTEKLLRGK-PDGTFLVRESTNFPGDFTLCMSFHGKVEHYRIEQ 202
>UniRef50_Q5BXT3 Cluster: SJCHGC03955 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC03955 protein - Schistosoma
japonicum (Blood fluke)
Length = 190
Score = 60.9 bits (141), Expect = 4e-08
Identities = 27/66 (40%), Positives = 41/66 (62%)
Frame = +1
Query: 295 NWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAF 474
+W+HG +SR++ E LL+ G G FLVR S ++PG ++V H G+V HY+I + F
Sbjct: 77 SWYHGAVSRQAGEHLLRS-GITGSFLVRASESAPGQLSVTVRHLGRVYHYRISQDSRGLF 135
Query: 475 FSIEEH 492
+ E H
Sbjct: 136 YITEAH 141
>UniRef50_A2RQD6 Cluster: Bcr-abl1 e6a2 chimeric protein; n=10;
Euteleostomi|Rep: Bcr-abl1 e6a2 chimeric protein - Homo
sapiens (Human)
Length = 585
Score = 60.9 bits (141), Expect = 4e-08
Identities = 28/78 (35%), Positives = 48/78 (61%)
Frame = +1
Query: 256 NSFLLRMNREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQV 435
++++ +N + +W+HG +SR +AE LL G +G FLVRES +SPG +S+ ++G+V
Sbjct: 452 SNYITPVNSLEKHSWYHGPVSRNAAEYLLSS-GINGSFLVRESESSPGQRSISLRYEGRV 510
Query: 436 VHYQIRRHGEDAFFSIEE 489
HY+I + + E
Sbjct: 511 YHYRINTASDGKLYVSSE 528
>UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase
ABL1; n=35; root|Rep: Proto-oncogene tyrosine-protein
kinase ABL1 - Homo sapiens (Human)
Length = 1130
Score = 60.9 bits (141), Expect = 4e-08
Identities = 28/78 (35%), Positives = 48/78 (61%)
Frame = +1
Query: 256 NSFLLRMNREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQV 435
++++ +N + +W+HG +SR +AE LL G +G FLVRES +SPG +S+ ++G+V
Sbjct: 113 SNYITPVNSLEKHSWYHGPVSRNAAEYLLSS-GINGSFLVRESESSPGQRSISLRYEGRV 171
Query: 436 VHYQIRRHGEDAFFSIEE 489
HY+I + + E
Sbjct: 172 YHYRINTASDGKLYVSSE 189
>UniRef50_UPI0000F2E785 Cluster: PREDICTED: hypothetical protein;
n=1; Monodelphis domestica|Rep: PREDICTED: hypothetical
protein - Monodelphis domestica
Length = 197
Score = 60.5 bits (140), Expect = 5e-08
Identities = 27/55 (49%), Positives = 39/55 (70%)
Frame = +1
Query: 286 DNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
D+V+ +HG ISRE+ EKLL G DG +L+R+S + PG Y L VL+QG + Y++
Sbjct: 2 DSVSVYHGNISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYQGYIYTYRV 56
>UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming
protein Abl; n=57; root|Rep: Tyrosine-protein kinase
transforming protein Abl - Feline sarcoma virus (strain
Hardy-Zuckerman 2)
Length = 439
Score = 60.5 bits (140), Expect = 5e-08
Identities = 27/65 (41%), Positives = 45/65 (69%)
Frame = +1
Query: 256 NSFLLRMNREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQV 435
++++ +N + +W+HG +SR +AE LL G +G FLVRES +SPG +S+ ++G+V
Sbjct: 62 SNYITPVNSLEKHSWYHGPVSRNAAEYLLSS-GINGSFLVRESESSPGQRSISLRYEGRV 120
Query: 436 VHYQI 450
HY+I
Sbjct: 121 YHYRI 125
>UniRef50_A2RQD3 Cluster: Bcr-abl1 e13a3 chimeric protein; n=21;
Eumetazoa|Rep: Bcr-abl1 e13a3 chimeric protein - Homo
sapiens (Human)
Length = 235
Score = 60.1 bits (139), Expect = 7e-08
Identities = 28/78 (35%), Positives = 47/78 (60%)
Frame = +1
Query: 256 NSFLLRMNREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQV 435
++++ N + +W+HG +SR +AE LL G +G FLVRES +SPG +S+ ++G+V
Sbjct: 102 SNYITPANSLEKHSWYHGPVSRNAAEYLLSS-GINGSFLVRESESSPGQRSISLRYEGRV 160
Query: 436 VHYQIRRHGEDAFFSIEE 489
HY+I + + E
Sbjct: 161 YHYRINTASDGKLYVSSE 178
>UniRef50_Q06124 Cluster: Tyrosine-protein phosphatase non-receptor
type 11; n=73; Bilateria|Rep: Tyrosine-protein
phosphatase non-receptor type 11 - Homo sapiens (Human)
Length = 597
Score = 60.1 bits (139), Expect = 7e-08
Identities = 31/66 (46%), Positives = 41/66 (62%)
Frame = +1
Query: 220 DNNHDVIHIT*ENSFLLRMNREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPG 399
+ N DVI + + L + WFHG +S + AEKLL E+G+ G FLVRES + PG
Sbjct: 90 EKNGDVIEL----KYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPG 145
Query: 400 DYVLSV 417
D+VLSV
Sbjct: 146 DFVLSV 151
Score = 57.2 bits (132), Expect = 5e-07
Identities = 26/56 (46%), Positives = 33/56 (58%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGE 465
WFH I+ AE LL G DG FL R S ++PGD+ LSV G V H +I+ G+
Sbjct: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGD 61
>UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming
protein Abl; n=15; root|Rep: Tyrosine-protein kinase
transforming protein Abl - Abelson murine leukemia virus
Length = 746
Score = 60.1 bits (139), Expect = 7e-08
Identities = 28/76 (36%), Positives = 46/76 (60%)
Frame = +1
Query: 262 FLLRMNREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVH 441
++ +N + +W+HG +SR +AE LL G +G FLVRES +SPG +S+ ++G+V H
Sbjct: 1 YITPVNSLEKHSWYHGPVSRNAAEYLLSS-GINGSFLVRESESSPGQRSISLRYEGRVYH 59
Query: 442 YQIRRHGEDAFFSIEE 489
Y+I + + E
Sbjct: 60 YRINTASDGKLYVSSE 75
>UniRef50_O60880 Cluster: SH2 domain-containing protein 1A; n=18;
Euteleostomi|Rep: SH2 domain-containing protein 1A -
Homo sapiens (Human)
Length = 128
Score = 59.7 bits (138), Expect = 9e-08
Identities = 32/73 (43%), Positives = 44/73 (60%)
Frame = +1
Query: 286 DNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGE 465
D V +HGKISRE+ EKLL G DG +L+R+S + PG Y L VL+ G + Y++ + E
Sbjct: 2 DAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQ-TE 60
Query: 466 DAFFSIEEHTTVH 504
+S E VH
Sbjct: 61 TGSWSAETAPGVH 73
>UniRef50_Q5ZM15 Cluster: Putative uncharacterized protein; n=3;
Gallus gallus|Rep: Putative uncharacterized protein -
Gallus gallus (Chicken)
Length = 431
Score = 59.3 bits (137), Expect = 1e-07
Identities = 25/41 (60%), Positives = 33/41 (80%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVL 420
W+HG ++ + AEKLL E+G+ G FLVRES + PGD+VLSVL
Sbjct: 110 WYHGHLTGKEAEKLLTEKGKPGSFLVRESQSKPGDFVLSVL 150
Score = 57.2 bits (132), Expect = 5e-07
Identities = 27/58 (46%), Positives = 34/58 (58%)
Frame = +1
Query: 292 VNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGE 465
V WFH IS AEKLL G G FL R S ++PGD+ LSV +V H +I+ G+
Sbjct: 2 VRWFHPNISGIEAEKLLLTRGVHGSFLARPSKSNPGDFTLSVRRNDEVTHIKIQNTGD 59
>UniRef50_Q7PV64 Cluster: ENSANGP00000020137; n=5; Coelomata|Rep:
ENSANGP00000020137 - Anopheles gambiae str. PEST
Length = 185
Score = 59.3 bits (137), Expect = 1e-07
Identities = 28/63 (44%), Positives = 41/63 (65%)
Frame = +1
Query: 289 NVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGED 468
N +W++G+I+R AEKLL + E G FL+R S +SPGD+ LSV V H+++ R +
Sbjct: 31 NHDWYYGRITRADAEKLLSNKHE-GAFLIRISESSPGDFSLSVKCSDGVQHFKVLRDAQG 89
Query: 469 AFF 477
FF
Sbjct: 90 KFF 92
>UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-protein
kinase; n=38; Euteleostomi|Rep: Megakaryocyte-associated
tyrosine-protein kinase - Homo sapiens (Human)
Length = 507
Score = 59.3 bits (137), Expect = 1e-07
Identities = 31/64 (48%), Positives = 40/64 (62%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAFF 477
WFHGKIS + A + L+ EDG+FLVRES PGDYVL V V+HY++ D
Sbjct: 122 WFHGKISGQEAVQQLQPP-EDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLH--RDGHL 178
Query: 478 SIEE 489
+I+E
Sbjct: 179 TIDE 182
>UniRef50_P42685 Cluster: Tyrosine-protein kinase FRK; n=27;
Fungi/Metazoa group|Rep: Tyrosine-protein kinase FRK -
Homo sapiens (Human)
Length = 505
Score = 58.8 bits (136), Expect = 2e-07
Identities = 30/61 (49%), Positives = 37/61 (60%), Gaps = 1/61 (1%)
Frame = +1
Query: 298 WFHGKISRESAEK-LLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAF 474
WF G I R AEK LL E + G FL+RES + G++ LSVL V HY+I+R E F
Sbjct: 116 WFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYRIKRLDEGGF 175
Query: 475 F 477
F
Sbjct: 176 F 176
>UniRef50_Q6DEM2 Cluster: V-crk sarcoma virus CT10 oncogene homolog;
n=5; Clupeocephala|Rep: V-crk sarcoma virus CT10
oncogene homolog - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 311
Score = 58.4 bits (135), Expect = 2e-07
Identities = 29/56 (51%), Positives = 38/56 (67%)
Frame = +1
Query: 283 EDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
ED +W+ G++SR+ A LL+ + GVFLVR+S T PGDYVLSV +V HY I
Sbjct: 8 EDRGSWYWGRLSRQEAVSLLQGQ-RHGVFLVRDSITIPGDYVLSVSENSKVSHYII 62
>UniRef50_Q7QHE3 Cluster: ENSANGP00000022029; n=2; Anopheles gambiae
str. PEST|Rep: ENSANGP00000022029 - Anopheles gambiae
str. PEST
Length = 1230
Score = 58.4 bits (135), Expect = 2e-07
Identities = 32/57 (56%), Positives = 38/57 (66%), Gaps = 4/57 (7%)
Frame = +1
Query: 295 NWFHGKIS--RESAEKLLKEEGE--DGVFLVRESNTSPGDYVLSVLHQGQVVHYQIR 453
NWFHGK+S RE AEKLL++ DG FLVRES T GDY LS QG+ H +I+
Sbjct: 569 NWFHGKLSGGREEAEKLLQQFSHLGDGTFLVRESVTFVGDYCLSFWRQGKPNHCRIK 625
Score = 45.6 bits (103), Expect = 0.002
Identities = 21/62 (33%), Positives = 33/62 (53%)
Frame = +1
Query: 277 NREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
N+ + W+H +RE +E +L + +DG FLVR S +V+S G+ H +IR
Sbjct: 675 NKHETKEWYHQTTTREQSEIVLNQIPQDGAFLVRPSEKGTKAFVISFRAHGKFKHCRIRV 734
Query: 457 HG 462
G
Sbjct: 735 EG 736
>UniRef50_UPI0000E479E4 Cluster: PREDICTED: similar to Sh2d3c-prov
protein, partial; n=2; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Sh2d3c-prov
protein, partial - Strongylocentrotus purpuratus
Length = 926
Score = 58.0 bits (134), Expect = 3e-07
Identities = 26/53 (49%), Positives = 39/53 (73%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
WFHG ISRE AEKL++E G+ FLVR+S + PG++VL+V +G +H+ + +
Sbjct: 126 WFHGGISREKAEKLIRENGD---FLVRDSISKPGNFVLTVRWKGVSMHFVVNK 175
>UniRef50_Q7QG48 Cluster: ENSANGP00000010943; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000010943 - Anopheles gambiae
str. PEST
Length = 256
Score = 58.0 bits (134), Expect = 3e-07
Identities = 29/65 (44%), Positives = 39/65 (60%), Gaps = 2/65 (3%)
Frame = +1
Query: 286 DNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR--H 459
D +W+ G +SR+ A LL E E GVFLVR+S T GD+VL V +V HY I +
Sbjct: 8 DRSSWYFGAMSRQDATDLLLNERESGVFLVRDSTTIVGDFVLCVREDSKVSHYIINKLPS 67
Query: 460 GEDAF 474
G++ F
Sbjct: 68 GDECF 72
>UniRef50_Q0PIN0 Cluster: Bam32; n=1; Branchiostoma belcheri
tsingtauense|Rep: Bam32 - Branchiostoma belcheri
tsingtauense
Length = 250
Score = 58.0 bits (134), Expect = 3e-07
Identities = 29/72 (40%), Positives = 41/72 (56%)
Frame = +1
Query: 268 LRMNREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQ 447
LR + ++W+HG +SR AE LL EDG +L+R S T G+Y LSV + V H+Q
Sbjct: 4 LRNLEVEQLDWYHGDLSRHMAEALLMANAEDGSYLLRSSATRVGEYSLSVKCKDSVKHFQ 63
Query: 448 IRRHGEDAFFSI 483
I G+ F +
Sbjct: 64 IGWDGKQYQFGM 75
>UniRef50_Q22070 Cluster: Putative uncharacterized protein plc-3;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein plc-3 - Caenorhabditis elegans
Length = 1299
Score = 57.6 bits (133), Expect = 4e-07
Identities = 25/54 (46%), Positives = 38/54 (70%), Gaps = 2/54 (3%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGE--DGVFLVRESNTSPGDYVLSVLHQGQVVHYQIR 453
WFHG+ R+ A+K + E E +G+F++R+SN GD+ LS+LH G+V H +IR
Sbjct: 554 WFHGRCERDEAKKRILEHKEKGNGLFMIRDSNLFIGDFSLSILHDGKVHHVRIR 607
Score = 53.6 bits (123), Expect = 6e-06
Identities = 25/58 (43%), Positives = 34/58 (58%)
Frame = +1
Query: 289 NVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHG 462
N WF +E AE+LL EDG FL+R S+T YVLS+ G+ HY+++R G
Sbjct: 661 NQPWFSATADKEKAEELLSLVPEDGAFLIRTSSTDSSVYVLSLKVDGEFWHYRLKRDG 718
>UniRef50_Q5T185 Cluster: SHC (Src homology 2 domain containing)
transforming protein 1 (SHC (Src homology 2 domain
containing) transforming protein 1, isoform CRA_c); n=8;
Theria|Rep: SHC (Src homology 2 domain containing)
transforming protein 1 (SHC (Src homology 2 domain
containing) transforming protein 1, isoform CRA_c) -
Homo sapiens (Human)
Length = 473
Score = 57.6 bits (133), Expect = 4e-07
Identities = 28/48 (58%), Positives = 33/48 (68%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVH 441
WFHGK+SR AE LL+ G+ FLVRES T+PG YVL+ L GQ H
Sbjct: 378 WFHGKLSRREAEALLQLNGD---FLVRESTTTPGQYVLTGLQSGQPKH 422
>UniRef50_Q59HB0 Cluster: SHC (Src homology 2 domain containing)
transforming protein 1 isoform p66Shc variant; n=9;
Tetrapoda|Rep: SHC (Src homology 2 domain containing)
transforming protein 1 isoform p66Shc variant - Homo
sapiens (Human)
Length = 377
Score = 57.6 bits (133), Expect = 4e-07
Identities = 28/48 (58%), Positives = 33/48 (68%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVH 441
WFHGK+SR AE LL+ G+ FLVRES T+PG YVL+ L GQ H
Sbjct: 267 WFHGKLSRREAEALLQLNGD---FLVRESTTTPGQYVLTGLQSGQPKH 311
>UniRef50_O15357 Cluster: Phosphatidylinositol-3,4,5-trisphosphate
5-phosphatase 2; n=24; Euteleostomi|Rep:
Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2
- Homo sapiens (Human)
Length = 1258
Score = 57.6 bits (133), Expect = 4e-07
Identities = 28/64 (43%), Positives = 41/64 (64%)
Frame = +1
Query: 295 NWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAF 474
+W+H +SR +AE+LL G DG FLVR+S + G + L VL+Q V Y+I GED F
Sbjct: 20 SWYHRDLSRAAAEELLARAGRDGSFLVRDSESVAGAFALCVLYQKHVHTYRILPDGED-F 78
Query: 475 FSIE 486
+++
Sbjct: 79 LAVQ 82
>UniRef50_P29353 Cluster: SHC-transforming protein 1; n=46;
Tetrapoda|Rep: SHC-transforming protein 1 - Homo sapiens
(Human)
Length = 583
Score = 57.6 bits (133), Expect = 4e-07
Identities = 28/48 (58%), Positives = 33/48 (68%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVH 441
WFHGK+SR AE LL+ G+ FLVRES T+PG YVL+ L GQ H
Sbjct: 488 WFHGKLSRREAEALLQLNGD---FLVRESTTTPGQYVLTGLQSGQPKH 532
>UniRef50_UPI0000E46C42 Cluster: PREDICTED: similar to Grb14; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
Grb14 - Strongylocentrotus purpuratus
Length = 756
Score = 57.2 bits (132), Expect = 5e-07
Identities = 28/68 (41%), Positives = 41/68 (60%), Gaps = 1/68 (1%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGE-DGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAF 474
WFH ++R+ L ++G DG+FL+RES PG +VLS H +V HYQI ED
Sbjct: 660 WFHSGLTRDETHALFAKQGMVDGMFLIRESQRIPGAFVLSFSHNQKVKHYQINM-VEDGV 718
Query: 475 FSIEEHTT 498
++I++ T
Sbjct: 719 YTIDDGGT 726
>UniRef50_UPI00015A4B5A Cluster: protein tyrosine phosphatase,
non-receptor type 11 (Noonan syndrome 1); n=1; Danio
rerio|Rep: protein tyrosine phosphatase, non-receptor
type 11 (Noonan syndrome 1) - Danio rerio
Length = 564
Score = 57.2 bits (132), Expect = 5e-07
Identities = 26/56 (46%), Positives = 33/56 (58%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGE 465
WFH I+ AE LL G DG FL R S ++PGD+ LSV G V H +I+ G+
Sbjct: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGD 61
>UniRef50_Q8WPV5 Cluster: Tyrosine kinase; n=2; Eumetazoa|Rep:
Tyrosine kinase - Schistosoma mansoni (Blood fluke)
Length = 1264
Score = 57.2 bits (132), Expect = 5e-07
Identities = 27/64 (42%), Positives = 44/64 (68%), Gaps = 1/64 (1%)
Frame = +1
Query: 286 DNVNWFHGKISRESAEKLLKEEG-EDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHG 462
++ N+F+GKI+RE AE+LL G +G+FL+RES +Y +S+ H G+V HY + RH
Sbjct: 45 ESTNYFYGKITREQAEELLFTNGANEGLFLLRESVNR--NYAVSICHLGRVHHYNVERHT 102
Query: 463 EDAF 474
+ ++
Sbjct: 103 DCSY 106
Score = 41.5 bits (93), Expect = 0.025
Identities = 23/55 (41%), Positives = 29/55 (52%), Gaps = 1/55 (1%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEG-EDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRH 459
W+H I R AE L EG +DG FLVR YVLS+ Q + HY+I +
Sbjct: 202 WYHHTIRRYEAESRLASEGNQDGAFLVR-YRKEDRTYVLSLTSQNEPKHYRIEEY 255
>UniRef50_P98077 Cluster: SHC-transforming protein 2; n=15;
Tetrapoda|Rep: SHC-transforming protein 2 - Homo sapiens
(Human)
Length = 551
Score = 57.2 bits (132), Expect = 5e-07
Identities = 24/48 (50%), Positives = 37/48 (77%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVH 441
W+HG++SR +AE++L+ +G+ FLVR+S T+PG YVL+ +H GQ H
Sbjct: 456 WYHGRMSRRAAERMLRADGD---FLVRDSVTNPGQYVLTGMHAGQPKH 500
>UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38;
Euteleostomi|Rep: Tyrosine-protein kinase ABL2 - Homo
sapiens (Human)
Length = 1182
Score = 57.2 bits (132), Expect = 5e-07
Identities = 26/65 (40%), Positives = 44/65 (67%)
Frame = +1
Query: 256 NSFLLRMNREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQV 435
++++ +N + +W+HG +SR +AE LL +G FLVRES +SPG +S+ ++G+V
Sbjct: 159 SNYITPVNSLEKHSWYHGPVSRSAAEYLLSSL-INGSFLVRESESSPGQLSISLRYEGRV 217
Query: 436 VHYQI 450
HY+I
Sbjct: 218 YHYRI 222
>UniRef50_Q8BZ27 Cluster: Adult female vagina cDNA, RIKEN
full-length enriched library, clone:9930020J04
product:similar to epidermal growth factor-receptor-
binding protein GRB-4; n=5; Eutheria|Rep: Adult female
vagina cDNA, RIKEN full-length enriched library,
clone:9930020J04 product:similar to epidermal growth
factor-receptor- binding protein GRB-4 - Mus musculus
(Mouse)
Length = 123
Score = 56.8 bits (131), Expect = 6e-07
Identities = 21/52 (40%), Positives = 37/52 (71%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIR 453
W++GK++R AE L E G +G FL+R+S +SP D+ +S+ QG+ H++++
Sbjct: 28 WYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQ 79
>UniRef50_O77440 Cluster: Protein-tyrosine kinase HTK98; n=1; Hydra
vulgaris|Rep: Protein-tyrosine kinase HTK98 - Hydra
attenuata (Hydra) (Hydra vulgaris)
Length = 624
Score = 56.8 bits (131), Expect = 6e-07
Identities = 24/49 (48%), Positives = 31/49 (63%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHY 444
WFHG I R AE+ LK E G+FL+RE + G YV+ + +QG V HY
Sbjct: 161 WFHGVIPRTEAERRLKSLSETGMFLIRERGSPRGSYVIGLFYQGGVYHY 209
Score = 56.0 bits (129), Expect = 1e-06
Identities = 26/57 (45%), Positives = 38/57 (66%), Gaps = 2/57 (3%)
Frame = +1
Query: 292 VNWFHGKISRESAEKLLKEEG--EDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
+ WFHG+I+R+ AE L+ +DG +L+RES + G YVLSV +V+HY I+R
Sbjct: 7 LRWFHGRITRDIAENCLQTTTSMDDGTYLLRESASEIGSYVLSVCKDKKVIHYAIQR 63
>UniRef50_P20936 Cluster: Ras GTPase-activating protein 1; n=50;
Euteleostomi|Rep: Ras GTPase-activating protein 1 - Homo
sapiens (Human)
Length = 1047
Score = 56.8 bits (131), Expect = 6e-07
Identities = 25/52 (48%), Positives = 37/52 (71%), Gaps = 1/52 (1%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVV-HYQI 450
W+HGK+ R AE+ L++ G+ G +L+RES+ PG +VLS L Q VV H++I
Sbjct: 181 WYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRI 232
Score = 46.8 bits (106), Expect = 7e-04
Identities = 21/38 (55%), Positives = 26/38 (68%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVL 411
WFHGKIS++ A LL G+ FLVR S+ +PGDY L
Sbjct: 351 WFHGKISKQEAYNLLMTVGQVCSFLVRPSDNTPGDYSL 388
>UniRef50_O75791 Cluster: GRB2-related adapter protein 2; n=22;
Amniota|Rep: GRB2-related adapter protein 2 - Homo
sapiens (Human)
Length = 330
Score = 56.8 bits (131), Expect = 6e-07
Identities = 25/60 (41%), Positives = 38/60 (63%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAFF 477
WFH +SR AE LL + E G F++R S +SPGD+ +SV H+ V H+++ R + +F
Sbjct: 58 WFHEGLSRHQAENLLMGK-EVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNYF 116
>UniRef50_UPI00006A0BC0 Cluster: Growth factor receptor-bound
protein 14 (GRB14 adapter protein).; n=5; Tetrapoda|Rep:
Growth factor receptor-bound protein 14 (GRB14 adapter
protein). - Xenopus tropicalis
Length = 428
Score = 56.4 bits (130), Expect = 8e-07
Identities = 28/70 (40%), Positives = 47/70 (67%), Gaps = 3/70 (4%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEG-EDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDA- 471
WFH ++SR+ A+KL+ ++G DGVF++R+S ++ +VLS+ H +V H+QI ED
Sbjct: 327 WFHHQLSRDEAQKLILQQGLVDGVFILRDSQSTHKAFVLSMCHGQKVKHFQIVPVEEDGD 386
Query: 472 -FFSIEEHTT 498
FF+++ T
Sbjct: 387 HFFTLDNAQT 396
>UniRef50_UPI000065EFEA Cluster: Growth factor receptor-bound
protein 7 (GRB7 adapter protein) (Epidermal growth
factor receptor GRB-7) (B47).; n=1; Takifugu
rubripes|Rep: Growth factor receptor-bound protein 7
(GRB7 adapter protein) (Epidermal growth factor receptor
GRB-7) (B47). - Takifugu rubripes
Length = 485
Score = 56.4 bits (130), Expect = 8e-07
Identities = 27/71 (38%), Positives = 47/71 (66%), Gaps = 3/71 (4%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEG-EDGVFLVRESNTSPGDYVLSVLHQGQVVHYQI--RRHGED 468
WFHG +SR+ A++L++++G DG+FL+RES +VLS+ HQ ++ HY + G
Sbjct: 384 WFHGGVSRKEAQRLIEKQGLVDGMFLIRESQQHGQCFVLSLSHQLKIKHYLVIPCEDGGR 443
Query: 469 AFFSIEEHTTV 501
+F+I++ T+
Sbjct: 444 KYFTIDDGLTL 454
>UniRef50_Q4SS18 Cluster: Chromosome undetermined SCAF14482, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF14482, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 621
Score = 56.4 bits (130), Expect = 8e-07
Identities = 26/64 (40%), Positives = 42/64 (65%), Gaps = 1/64 (1%)
Frame = +1
Query: 268 LRMNREDNVNWFHGKISRESAEKLLKEEGE-DGVFLVRESNTSPGDYVLSVLHQGQVVHY 444
+ + + + WFHG I+RE +E L+ +G FLVR+ +T+ G Y L +LH+GQV+HY
Sbjct: 153 IAITAHERMVWFHGAITREGSEPRLQNGSRINGRFLVRQRDTN-GSYALCLLHEGQVMHY 211
Query: 445 QIRR 456
++ R
Sbjct: 212 RVDR 215
Score = 50.0 bits (114), Expect = 7e-05
Identities = 26/67 (38%), Positives = 40/67 (59%), Gaps = 4/67 (5%)
Frame = +1
Query: 286 DNVN---WFHGKISRESAEKLLKEEG-EDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIR 453
DNV+ +F+G I+RE AE L+ G DG++L+R+S + G + LSV G+ HY I
Sbjct: 3 DNVSALPFFYGNITREEAEDYLQLAGMADGLYLLRQSRNNLGGFALSVSSSGRSYHYSIE 62
Query: 454 RHGEDAF 474
R + +
Sbjct: 63 RQANETY 69
>UniRef50_P16591 Cluster: Proto-oncogene tyrosine-protein kinase
FER; n=109; root|Rep: Proto-oncogene tyrosine-protein
kinase FER - Homo sapiens (Human)
Length = 822
Score = 56.4 bits (130), Expect = 8e-07
Identities = 27/53 (50%), Positives = 38/53 (71%)
Frame = +1
Query: 295 NWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIR 453
+W+HG I R A++LLK++G+ FLVRES+ PG+YVLSV GQ H+ I+
Sbjct: 459 DWYHGAIPRIEAQELLKKQGD---FLVRESHGKPGEYVLSVYSDGQRRHFIIQ 508
>UniRef50_Q9UN19 Cluster: Dual adapter for phosphotyrosine and
3-phosphotyrosine and 3- phosphoinositide; n=25;
Euteleostomi|Rep: Dual adapter for phosphotyrosine and
3-phosphotyrosine and 3- phosphoinositide - Homo sapiens
(Human)
Length = 280
Score = 56.4 bits (130), Expect = 8e-07
Identities = 25/75 (33%), Positives = 43/75 (57%)
Frame = +1
Query: 289 NVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGED 468
++ W+HG ++R +AE LL G DG +L+R+SN + G Y LSV + V H+ + G
Sbjct: 32 DLGWYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYTGYS 91
Query: 469 AFFSIEEHTTVHGWI 513
F E +++ ++
Sbjct: 92 FKFGFNEFSSLKDFV 106
>UniRef50_UPI00015B564A Cluster: PREDICTED: similar to CRK protein;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to CRK
protein - Nasonia vitripennis
Length = 298
Score = 56.0 bits (129), Expect = 1e-06
Identities = 26/60 (43%), Positives = 37/60 (61%)
Frame = +1
Query: 277 NREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
++ D +W+ G +SR+ A LL E E GVFLVR+S + GD+VL V +V HY I +
Sbjct: 6 DQNDKSSWYFGAMSRQDASDLLMSEKEGGVFLVRDSISIQGDFVLCVREDSKVSHYIINK 65
>UniRef50_P43405 Cluster: Tyrosine-protein kinase SYK; n=23;
Theria|Rep: Tyrosine-protein kinase SYK - Homo sapiens
(Human)
Length = 635
Score = 55.2 bits (127), Expect = 2e-06
Identities = 26/63 (41%), Positives = 41/63 (65%), Gaps = 1/63 (1%)
Frame = +1
Query: 265 LLRMNREDNVNWFHGKISRESAEKL-LKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVH 441
L+ + + WFHGKISRE +E++ L +G FL+R + + G Y L +LH+G+V+H
Sbjct: 157 LIATTAHEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNN-GSYALCLLHEGKVLH 215
Query: 442 YQI 450
Y+I
Sbjct: 216 YRI 218
Score = 45.6 bits (103), Expect = 0.002
Identities = 23/58 (39%), Positives = 35/58 (60%), Gaps = 1/58 (1%)
Frame = +1
Query: 286 DNVNWFHGKISRESAEKLLKEEG-EDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
+++ +F G I+RE AE L + G DG++L+R+S G + LSV H + HY I R
Sbjct: 11 NHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTIER 68
>UniRef50_Q9XYM0 Cluster: Adapter molecule Crk; n=7;
Endopterygota|Rep: Adapter molecule Crk - Drosophila
melanogaster (Fruit fly)
Length = 271
Score = 55.2 bits (127), Expect = 2e-06
Identities = 26/57 (45%), Positives = 37/57 (64%)
Frame = +1
Query: 286 DNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
D +W+ G +SR+ A ++L E E GVFLVR+SN+ GDYVL V +V +Y I +
Sbjct: 8 DRNSWYFGPMSRQDATEVLMNERERGVFLVRDSNSIAGDYVLCVREDTKVSNYIINK 64
>UniRef50_UPI000065FE19 Cluster: SHC-transforming protein 1 (SH2
domain protein C1) (Src homology 2
domain-containing-transforming protein C1).; n=2;
Euteleostomi|Rep: SHC-transforming protein 1 (SH2 domain
protein C1) (Src homology 2
domain-containing-transforming protein C1). - Takifugu
rubripes
Length = 526
Score = 54.4 bits (125), Expect = 3e-06
Identities = 26/48 (54%), Positives = 33/48 (68%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVH 441
WFHG +SR+ AE+LL +G+ FLVRES T+PG YVL+ GQ H
Sbjct: 432 WFHGGLSRKEAERLLTRDGD---FLVRESGTTPGQYVLTGQQGGQPKH 476
>UniRef50_Q4TEC1 Cluster: Chromosome undetermined SCAF5507, whole
genome shotgun sequence; n=3; Tetraodontidae|Rep:
Chromosome undetermined SCAF5507, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1116
Score = 54.4 bits (125), Expect = 3e-06
Identities = 25/61 (40%), Positives = 39/61 (63%), Gaps = 1/61 (1%)
Frame = +1
Query: 298 WFHGKISRESAEKLL-KEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAF 474
W++G I+R AEKLL + +DG FLVR S + +Y +S +G+V H++I+R A+
Sbjct: 250 WYYGNINRVKAEKLLLASQNKDGSFLVRISESHSDEYTISARSEGKVFHFRIQRSSIGAY 309
Query: 475 F 477
F
Sbjct: 310 F 310
Score = 45.6 bits (103), Expect = 0.002
Identities = 23/61 (37%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
Frame = +1
Query: 298 WFHGKISRESAEK-LLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAF 474
WF G ++R A+ LL E +G FL+R S YVLSV QV HY++ + ++ F
Sbjct: 69 WFFGTLNRLQAQSHLLAPENSEGAFLIRVSEKDNVGYVLSVRSGDQVKHYKVLQTDQNRF 128
Query: 475 F 477
+
Sbjct: 129 Y 129
Score = 34.7 bits (76), Expect = 2.9
Identities = 16/43 (37%), Positives = 24/43 (55%)
Frame = +1
Query: 349 EGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAFF 477
E +G FL+R S YVLSV QV HY++ + ++ F+
Sbjct: 732 ENSEGAFLIRVSEKDNVGYVLSVRSGDQVKHYKVLQTDQNRFY 774
>UniRef50_Q4SVT4 Cluster: Chromosome undetermined SCAF13726, whole
genome shotgun sequence; n=2; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF13726,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 1377
Score = 54.4 bits (125), Expect = 3e-06
Identities = 33/65 (50%), Positives = 39/65 (60%), Gaps = 9/65 (13%)
Frame = +1
Query: 298 WFHGKIS-----RESAEKLLKE--EG--EDGVFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
WFHGK+ R+ AEKLL+E EG +DG FLVRES T GDY LS G+V H +I
Sbjct: 570 WFHGKLGGGRDGRQVAEKLLQEYCEGGAKDGTFLVRESETFVGDYTLSFWRSGRVQHCRI 629
Query: 451 RRHGE 465
E
Sbjct: 630 HSRQE 634
Score = 44.0 bits (99), Expect = 0.005
Identities = 19/62 (30%), Positives = 34/62 (54%)
Frame = +1
Query: 277 NREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
N ++ W+H ++R AE +L DG FLVR+ + Y +S +G++ H +I++
Sbjct: 680 NAHESREWYHSSLTRVQAEHMLMRVPRDGAFLVRK-RSEHNSYAISFRAEGKIKHCRIQQ 738
Query: 457 HG 462
G
Sbjct: 739 EG 740
>UniRef50_Q4RIB1 Cluster: Chromosome 8 SCAF15044, whole genome
shotgun sequence; n=3; Percomorpha|Rep: Chromosome 8
SCAF15044, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 480
Score = 54.4 bits (125), Expect = 3e-06
Identities = 26/48 (54%), Positives = 33/48 (68%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVH 441
WFHG +SR+ AE+LL +G+ FLVRES T+PG YVL+ GQ H
Sbjct: 385 WFHGGLSRKEAERLLTRDGD---FLVRESGTTPGQYVLTGQQGGQPKH 429
>UniRef50_UPI0000D562ED Cluster: PREDICTED: similar to growth factor
receptor bound protein 14; n=1; Tribolium castaneum|Rep:
PREDICTED: similar to growth factor receptor bound
protein 14 - Tribolium castaneum
Length = 655
Score = 54.0 bits (124), Expect = 4e-06
Identities = 26/52 (50%), Positives = 36/52 (69%), Gaps = 1/52 (1%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGE-DGVFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
WFH +SR+ A L+ + G DGVFLVRES ++PG +VL+ G+V+H QI
Sbjct: 533 WFHSGMSRDQATALVTKHGTVDGVFLVRESRSNPGAFVLTYKCGGKVLHAQI 584
>UniRef50_Q1LWW1 Cluster: Novel protein similar to vertebrate
phospholipase C, gamma 2; n=4; Danio rerio|Rep: Novel
protein similar to vertebrate phospholipase C, gamma 2 -
Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 270
Score = 54.0 bits (124), Expect = 4e-06
Identities = 27/58 (46%), Positives = 41/58 (70%), Gaps = 7/58 (12%)
Frame = +1
Query: 298 WFHGKIS--RESAEKLLKE-----EGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
WFHG+++ R +AEKLL++ +G D FLVRESNT G+Y +S+ +G++ HY+I
Sbjct: 54 WFHGRLAEGRITAEKLLRDYCKGTDGNDETFLVRESNTFIGNYCISLWTRGRIQHYRI 111
Score = 47.6 bits (108), Expect = 4e-04
Identities = 31/86 (36%), Positives = 46/86 (53%), Gaps = 9/86 (10%)
Frame = +1
Query: 259 SFLLRMNRED--NVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQ 432
+FL R+N E ++ WF+ +SR AE L DG FL+R+ N + LS+ +G
Sbjct: 156 NFLPRLNFEPLHHMGWFYSNMSRAEAEDCLLRIPRDGAFLIRKRN-ERDTFALSIRSEGD 214
Query: 433 VVHYQIRRHGE-----DA--FFSIEE 489
+ HY+I R DA FFS+E+
Sbjct: 215 IKHYKIFRKSSKYVLADAYEFFSLED 240
>UniRef50_P29350 Cluster: Tyrosine-protein phosphatase non-receptor
type 6; n=39; Chordata|Rep: Tyrosine-protein phosphatase
non-receptor type 6 - Homo sapiens (Human)
Length = 595
Score = 54.0 bits (124), Expect = 4e-06
Identities = 28/67 (41%), Positives = 40/67 (59%)
Frame = +1
Query: 220 DNNHDVIHIT*ENSFLLRMNREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPG 399
D + +IH+ + L + + W+HG +S AE LL+ +GE FLVRES + PG
Sbjct: 88 DRDGTIIHL----KYPLNCSDPTSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPG 143
Query: 400 DYVLSVL 420
D+VLSVL
Sbjct: 144 DFVLSVL 150
Score = 51.6 bits (118), Expect = 2e-05
Identities = 40/120 (33%), Positives = 54/120 (45%), Gaps = 12/120 (10%)
Frame = +1
Query: 292 VNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGE-- 465
V WFH +S AE LLK G G FL R S + GD+ LSV QV H +I+ G+
Sbjct: 2 VRWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFY 61
Query: 466 -----DAFFSIE---EHTTVHGWILLYNITVVIQMDLLLGC--PLSVKENHHRMSRGHRE 615
+ F ++ E+ T +L +I + L C P S + H MS G E
Sbjct: 62 DLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGGQAE 121
>UniRef50_P05433 Cluster: P47(GAG-CRK) protein; n=3; root|Rep:
P47(GAG-CRK) protein - Avian sarcoma virus (strain CT10)
Length = 440
Score = 54.0 bits (124), Expect = 4e-06
Identities = 26/64 (40%), Positives = 39/64 (60%)
Frame = +1
Query: 271 RMNREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
+ + ED +W+ G++SR A LL+ + G FLVR+S + PGD+VLSV +V HY +
Sbjct: 239 QFDSEDRGSWYWGRLSRGDAVSLLQGQ-RHGTFLVRDSGSIPGDFVLSVSESSRVSHYIV 297
Query: 451 RRHG 462
G
Sbjct: 298 NSLG 301
>UniRef50_UPI0000660CF8 Cluster: Crk-like protein.; n=3;
Euteleostomi|Rep: Crk-like protein. - Takifugu rubripes
Length = 314
Score = 53.6 bits (123), Expect = 6e-06
Identities = 26/60 (43%), Positives = 37/60 (61%)
Frame = +1
Query: 271 RMNREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
R + D W+ G +SR A+ L+ + + G+FLVR+S+T GDYVLSV +V HY I
Sbjct: 5 RFDSADRSAWYFGPVSRHEAQNRLQGQ-KHGIFLVRDSSTCHGDYVLSVSENSKVSHYII 63
>UniRef50_Q4S8K3 Cluster: Chromosome 2 SCAF14705, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 2
SCAF14705, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 487
Score = 53.6 bits (123), Expect = 6e-06
Identities = 22/52 (42%), Positives = 38/52 (73%), Gaps = 1/52 (1%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEG-EDGVFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
WFHG +SR+ A++L++++G DG+FL+RES +VLS+ H+ ++ HY +
Sbjct: 368 WFHGGVSRKEAQRLIEKQGLVDGMFLIRESQQHAQCFVLSLCHKLKIKHYLV 419
>UniRef50_Q4RP74 Cluster: Chromosome 1 SCAF15008, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 1
SCAF15008, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 968
Score = 53.6 bits (123), Expect = 6e-06
Identities = 25/51 (49%), Positives = 33/51 (64%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
W+H ISR AE+LL G+DG +LVR+S + PG Y L +L Q V Y+I
Sbjct: 14 WYHRDISRVQAEELLARAGKDGSYLVRDSESVPGAYALCLLFQRHVHTYRI 64
>UniRef50_Q92529 Cluster: SHC-transforming protein 3; n=34;
Euteleostomi|Rep: SHC-transforming protein 3 - Homo
sapiens (Human)
Length = 594
Score = 53.6 bits (123), Expect = 6e-06
Identities = 23/48 (47%), Positives = 36/48 (75%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVH 441
W+ G++SR+ AE LL+++G+ FLVR+S T+PG +VL+ +H GQ H
Sbjct: 499 WYQGEMSRKEAEGLLEKDGD---FLVRKSTTNPGSFVLTGMHNGQAKH 543
>UniRef50_UPI0000D57912 Cluster: PREDICTED: similar to CG4200-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG4200-PA - Tribolium castaneum
Length = 1233
Score = 53.2 bits (122), Expect = 8e-06
Identities = 30/56 (53%), Positives = 35/56 (62%), Gaps = 4/56 (7%)
Frame = +1
Query: 298 WFHGKIS--RESAEKLLKEEGE--DGVFLVRESNTSPGDYVLSVLHQGQVVHYQIR 453
WFHGK++ RE AE+LLK DG FLVR S T G+Y LS GQV H +IR
Sbjct: 575 WFHGKLANGREEAEQLLKAYSHLGDGTFLVRASVTFVGEYCLSFWRNGQVNHCRIR 630
Score = 36.3 bits (80), Expect = 0.96
Identities = 15/61 (24%), Positives = 29/61 (47%)
Frame = +1
Query: 280 REDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRH 459
+ + W+H + A+++L+ +G FLVR S Y +S ++ H +I+
Sbjct: 681 KHETEEWYHKHTGKMQADEILRRVKMEGAFLVRPSENDANCYTISFRADKKIKHCRIKLE 740
Query: 460 G 462
G
Sbjct: 741 G 741
>UniRef50_UPI00004D6B5A Cluster: SH2B adapter protein 3
(Lymphocyte-specific adapter protein Lnk) (Signal
transduction protein Lnk) (Lymphocyte adapter protein).;
n=1; Xenopus tropicalis|Rep: SH2B adapter protein 3
(Lymphocyte-specific adapter protein Lnk) (Signal
transduction protein Lnk) (Lymphocyte adapter protein).
- Xenopus tropicalis
Length = 321
Score = 53.2 bits (122), Expect = 8e-06
Identities = 25/53 (47%), Positives = 36/53 (67%), Gaps = 2/53 (3%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDG--VFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
WFHG ISR A +L++ +G +G VFLVR+S T G+YVL+ QG+ H ++
Sbjct: 223 WFHGPISRVKAAQLVQSQGVEGHGVFLVRQSETRRGEYVLTFNFQGRAKHLRL 275
>UniRef50_UPI0000660CE1 Cluster: Homolog of Brachydanio rerio
"Phospholipase C gamma 1.; n=1; Takifugu rubripes|Rep:
Homolog of Brachydanio rerio "Phospholipase C gamma 1. -
Takifugu rubripes
Length = 1071
Score = 53.2 bits (122), Expect = 8e-06
Identities = 32/65 (49%), Positives = 39/65 (60%), Gaps = 9/65 (13%)
Frame = +1
Query: 298 WFHGKIS-----RESAEKLLKE--EG--EDGVFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
WFHGK+ R+ AEKLL++ EG +DG FLVRES T GDY LS G+V H +I
Sbjct: 502 WFHGKLGGGRDGRQVAEKLLQDYCEGGAKDGTFLVRESETFVGDYTLSFWRSGRVQHCRI 561
Query: 451 RRHGE 465
E
Sbjct: 562 HSRQE 566
Score = 46.0 bits (104), Expect = 0.001
Identities = 21/62 (33%), Positives = 35/62 (56%)
Frame = +1
Query: 277 NREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
N ++ W+H +SR AE +L DG FLVR+ + S Y +S +G++ H +I++
Sbjct: 612 NAHESREWYHSSLSRVQAEHMLMRVPRDGAFLVRKRSES-HSYAISFRAEGKIKHCRIQQ 670
Query: 457 HG 462
G
Sbjct: 671 EG 672
>UniRef50_Q4SAX0 Cluster: Chromosome 3 SCAF14679, whole genome
shotgun sequence; n=4; Tetraodontidae|Rep: Chromosome 3
SCAF14679, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 283
Score = 53.2 bits (122), Expect = 8e-06
Identities = 24/67 (35%), Positives = 39/67 (58%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAFF 477
WF SR +AE+LL+ +G G F++R +SPG++ +SV H+ V H+++ R +F
Sbjct: 58 WFQENASRSAAEELLRHKGV-GEFVIRGCQSSPGEFSISVRHESDVQHFKVMRDSRGQYF 116
Query: 478 SIEEHTT 498
E T
Sbjct: 117 LWSEKFT 123
>UniRef50_O77132 Cluster: Non-receptor protein-tyrosine kinase CSK;
n=1; Hydra vulgaris|Rep: Non-receptor protein-tyrosine
kinase CSK - Hydra attenuata (Hydra) (Hydra vulgaris)
Length = 467
Score = 53.2 bits (122), Expect = 8e-06
Identities = 28/54 (51%), Positives = 36/54 (66%), Gaps = 3/54 (5%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVL---HQGQVVHYQI 450
WF GKI+RE AE+LL E G+FLVRES PGDY L V+ + +V HY++
Sbjct: 92 WFFGKITREKAEELLTPR-EVGLFLVRESTNFPGDYTLCVVSPQNNKKVEHYRV 144
>UniRef50_A7RR81 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 473
Score = 53.2 bits (122), Expect = 8e-06
Identities = 26/49 (53%), Positives = 33/49 (67%)
Frame = +1
Query: 295 NWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVH 441
+W+HG ISR AE LL++EG+ FLVRES + PG YVLS + Q H
Sbjct: 378 DWYHGPISRGEAELLLEDEGD---FLVRESKSQPGQYVLSGIKDKQARH 423
>UniRef50_Q8N5H7 Cluster: SH2 domain-containing protein 3C; n=33;
Amniota|Rep: SH2 domain-containing protein 3C - Homo
sapiens (Human)
Length = 860
Score = 53.2 bits (122), Expect = 8e-06
Identities = 27/79 (34%), Positives = 46/79 (58%)
Frame = +1
Query: 220 DNNHDVIHIT*ENSFLLRMNREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPG 399
D++ + +H E L + W+HG+I RE +E L++ G+ FL+R+S TS G
Sbjct: 194 DSSPEKLHKELEEELKLSSTDLRSHAWYHGRIPREVSETLVQRNGD---FLIRDSLTSLG 250
Query: 400 DYVLSVLHQGQVVHYQIRR 456
DYVL+ + Q +H++I +
Sbjct: 251 DYVLTCRWRNQALHFKINK 269
>UniRef50_UPI00015B62FA Cluster: PREDICTED: similar to ras gtpase
activating protein; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ras gtpase activating protein -
Nasonia vitripennis
Length = 879
Score = 52.8 bits (121), Expect = 1e-05
Identities = 22/51 (43%), Positives = 35/51 (68%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
W+HG++ R +AE+ L++ G +LVRES+ PG YVLS L + + H++I
Sbjct: 77 WYHGRLDRFTAEERLRDASRLGSYLVRESDRKPGSYVLSYLGRTGINHFRI 127
Score = 44.4 bits (100), Expect = 0.004
Identities = 21/56 (37%), Positives = 32/56 (57%)
Frame = +1
Query: 295 NWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHG 462
+WFH +++ A +L + G G FLVR S+ SPGDY L Q+ ++I + G
Sbjct: 245 SWFHPNVTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKG 299
>UniRef50_UPI0000E49CFC Cluster: PREDICTED: similar to Ras
GTPase-activating protein 1 (GTPase-activating protein)
(GAP) (Ras p21 protein activator) (p120GAP) (RasGAP);
n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to Ras GTPase-activating protein 1
(GTPase-activating protein) (GAP) (Ras p21 protein
activator) (p120GAP) (RasGAP) - Strongylocentrotus
purpuratus
Length = 628
Score = 52.8 bits (121), Expect = 1e-05
Identities = 23/51 (45%), Positives = 32/51 (62%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
W+HG + R+SAE L + G +LVRES PG YVLS L Q + H+++
Sbjct: 68 WYHGCLDRQSAELRLNAADKPGSYLVRESERKPGSYVLSYLGQRGINHFRV 118
Score = 52.4 bits (120), Expect = 1e-05
Identities = 21/53 (39%), Positives = 35/53 (66%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
WFHG +S+E A + L ++G+ G FL+R S+ +PGDY LS + ++I++
Sbjct: 237 WFHGNVSKEEAAETLWKDGDIGGFLIRNSDKNPGDYSLSFRGPNTIQRFRIQK 289
>UniRef50_UPI0000E1FA37 Cluster: PREDICTED: similar to signaling
inositol polyphosphate 5 phosphatase SIP-145; n=1; Pan
troglodytes|Rep: PREDICTED: similar to signaling
inositol polyphosphate 5 phosphatase SIP-145 - Pan
troglodytes
Length = 177
Score = 52.8 bits (121), Expect = 1e-05
Identities = 26/59 (44%), Positives = 35/59 (59%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAF 474
W HG I+R AE+LL G+DG FLVR S + Y L VL++ V Y+I + +D F
Sbjct: 5 WNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKF 63
>UniRef50_UPI00015A7910 Cluster: hypothetical protein LOC553596;
n=2; Danio rerio|Rep: hypothetical protein LOC553596 -
Danio rerio
Length = 283
Score = 52.8 bits (121), Expect = 1e-05
Identities = 26/64 (40%), Positives = 40/64 (62%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAFF 477
WF G+ISR AE L + + G FLVRES ++PG++ +SV + V H+++ + E +F
Sbjct: 60 WFAGRISRHVAENRLHQR-DCGSFLVRESESAPGEFSMSVSYGDHVQHFKVLKDREGYYF 118
Query: 478 SIEE 489
EE
Sbjct: 119 VWEE 122
>UniRef50_UPI00006A1C31 Cluster: UPI00006A1C31 related cluster; n=1;
Xenopus tropicalis|Rep: UPI00006A1C31 UniRef100 entry -
Xenopus tropicalis
Length = 419
Score = 52.8 bits (121), Expect = 1e-05
Identities = 28/64 (43%), Positives = 43/64 (67%), Gaps = 3/64 (4%)
Frame = +1
Query: 268 LRMNRED--NVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVL-HQGQVV 438
L+++ ED + W+HG + R+ AE+LL G+ FL+R+S +SPGDYVLS GQ +
Sbjct: 3 LKLSSEDLRSHAWYHGPLPRQDAERLLVSNGD---FLIRDSISSPGDYVLSCFCAGGQPL 59
Query: 439 HYQI 450
H++I
Sbjct: 60 HFKI 63
>UniRef50_UPI00006A1C30 Cluster: UPI00006A1C30 related cluster; n=1;
Xenopus tropicalis|Rep: UPI00006A1C30 UniRef100 entry -
Xenopus tropicalis
Length = 514
Score = 52.8 bits (121), Expect = 1e-05
Identities = 28/64 (43%), Positives = 43/64 (67%), Gaps = 3/64 (4%)
Frame = +1
Query: 268 LRMNRED--NVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVL-HQGQVV 438
L+++ ED + W+HG + R+ AE+LL G+ FL+R+S +SPGDYVLS GQ +
Sbjct: 16 LKLSSEDLRSHAWYHGPLPRQDAERLLVSNGD---FLIRDSISSPGDYVLSCFCAGGQPL 72
Query: 439 HYQI 450
H++I
Sbjct: 73 HFKI 76
>UniRef50_A7S295 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 642
Score = 52.8 bits (121), Expect = 1e-05
Identities = 35/105 (33%), Positives = 55/105 (52%), Gaps = 7/105 (6%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEG-EDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRH---GE 465
WFHG+IS + A L+K EG EDG+FLVRES + YVL+ +V H Q+ + G
Sbjct: 534 WFHGRISHDEALVLMKREGFEDGLFLVRESCSVSDVYVLTFCMNKKVFHCQLVQDIGPGS 593
Query: 466 DAFFSIEE---HTTVHGWILLYNITVVIQMDLLLGCPLSVKENHH 591
++ +++ ++ I Y V + + LG P +VK +
Sbjct: 594 KMYYRLDKGPAFPSILELIRYYQRKTVNGISVALGRPCTVKRRRN 638
>UniRef50_Q2I6J0 Cluster: Phosphatidylinositol-3,4,5-trisphosphate
5-phosphatase 2B; n=6; Euteleostomi|Rep:
Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase
2B - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 1226
Score = 52.8 bits (121), Expect = 1e-05
Identities = 26/51 (50%), Positives = 32/51 (62%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
W+H ISR AE+LL G DG FLVR+S + PG Y L +L Q V Y+I
Sbjct: 6 WYHRDISRVRAEELLAHAGIDGSFLVRDSESVPGAYALCLLFQRHVHTYRI 56
>UniRef50_Q92835 Cluster: Phosphatidylinositol-3,4,5-trisphosphate
5-phosphatase 1; n=39; Euteleostomi|Rep:
Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1
- Homo sapiens (Human)
Length = 1189
Score = 52.8 bits (121), Expect = 1e-05
Identities = 26/59 (44%), Positives = 35/59 (59%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAF 474
W HG I+R AE+LL G+DG FLVR S + Y L VL++ V Y+I + +D F
Sbjct: 5 WNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKF 63
>UniRef50_UPI0000F318C3 Cluster: SH2B adapter protein 3
(Lymphocyte-specific adapter protein Lnk) (Signal
transduction protein Lnk) (Lymphocyte adapter protein).;
n=1; Bos taurus|Rep: SH2B adapter protein 3
(Lymphocyte-specific adapter protein Lnk) (Signal
transduction protein Lnk) (Lymphocyte adapter protein).
- Bos Taurus
Length = 526
Score = 52.4 bits (120), Expect = 1e-05
Identities = 26/53 (49%), Positives = 35/53 (66%), Gaps = 2/53 (3%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGED--GVFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
WFHG ISR A +L++ +G D GVFLVR+S T G+YVL+ QG H ++
Sbjct: 428 WFHGPISRVKAAQLVQLQGPDAHGVFLVRQSETRRGEYVLTFNFQGIAKHLRL 480
>UniRef50_Q4SMI9 Cluster: Chromosome 18 SCAF14547, whole genome
shotgun sequence; n=4; Clupeocephala|Rep: Chromosome 18
SCAF14547, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 609
Score = 52.4 bits (120), Expect = 1e-05
Identities = 26/65 (40%), Positives = 43/65 (66%), Gaps = 2/65 (3%)
Frame = +1
Query: 268 LRMNREDNVN--WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVH 441
L+++ ED + W+HG + RE+AE LL+ G+ FLVR+S+++P DYVL+ +H
Sbjct: 9 LKLSSEDLSSHAWYHGPLRREAAEALLERNGD---FLVRDSSSTPRDYVLTCFWMNMPMH 65
Query: 442 YQIRR 456
++I R
Sbjct: 66 FKIIR 70
>UniRef50_Q9UQQ2 Cluster: SH2B adapter protein 3; n=15;
Tetrapoda|Rep: SH2B adapter protein 3 - Homo sapiens
(Human)
Length = 575
Score = 52.4 bits (120), Expect = 1e-05
Identities = 26/53 (49%), Positives = 35/53 (66%), Gaps = 2/53 (3%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGED--GVFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
WFHG ISR A +L++ +G D GVFLVR+S T G+YVL+ QG H ++
Sbjct: 364 WFHGPISRVKAAQLVQLQGPDAHGVFLVRQSETRRGEYVLTFNFQGIAKHLRL 416
>UniRef50_UPI00015A79D6 Cluster: hypothetical protein LOC550452;
n=1; Danio rerio|Rep: hypothetical protein LOC550452 -
Danio rerio
Length = 250
Score = 52.0 bits (119), Expect = 2e-05
Identities = 31/95 (32%), Positives = 51/95 (53%), Gaps = 2/95 (2%)
Frame = +1
Query: 295 NWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAF 474
+WF SR SAE+ L E G FL+R S +SPGD+ +SV H V H+++ + +
Sbjct: 57 SWFKESASRGSAEETLMSR-EVGAFLIRGSQSSPGDFSISVRHDYDVQHFKVMKDKSGHY 115
Query: 475 FS-IEEHTTVHGWILLYNITVVI-QMDLLLGCPLS 573
+ E+ T+++ + Y T + Q ++ L LS
Sbjct: 116 YLWTEKFTSLNKLVDFYKTTSISKQKEIFLRLKLS 150
>UniRef50_Q4V9Q1 Cluster: Zgc:109892; n=11; Euteleostomi|Rep:
Zgc:109892 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 214
Score = 52.0 bits (119), Expect = 2e-05
Identities = 25/64 (39%), Positives = 41/64 (64%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAFF 477
WF G ISR++AE L+ E G FL+RES ++PG++ +SV + V H+++ + G +F
Sbjct: 60 WFVGGISRQAAENRLRPL-ECGAFLIRESESTPGEFSVSVSYGDHVQHFKVLKDGLGQYF 118
Query: 478 SIEE 489
+E
Sbjct: 119 IWDE 122
>UniRef50_Q4S516 Cluster: Chromosome 6 SCAF14737, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 6
SCAF14737, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 393
Score = 52.0 bits (119), Expect = 2e-05
Identities = 24/70 (34%), Positives = 43/70 (61%), Gaps = 6/70 (8%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRH------ 459
W++GK++R AE L + G +G FL+R+S +SP D+ +S+ Q + H++++
Sbjct: 297 WYYGKVTRHQAEVALNQRGVEGDFLIRDSESSPHDFSISLKAQSKNKHFKVQLKESLYCI 356
Query: 460 GEDAFFSIEE 489
G+ F S+EE
Sbjct: 357 GQRKFHSMEE 366
>UniRef50_Q1LX18 Cluster: Novel protein similar to vertebrate src
homology 2 domain containing transforming protein C3;
n=1; Danio rerio|Rep: Novel protein similar to
vertebrate src homology 2 domain containing transforming
protein C3 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 501
Score = 52.0 bits (119), Expect = 2e-05
Identities = 25/48 (52%), Positives = 32/48 (66%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVH 441
W+HG++SR AE LL G DG FLVR+S T+PG YVL+ + G H
Sbjct: 406 WYHGRMSRRDAENLL---GRDGDFLVRDSATNPGQYVLTGMQCGLPKH 450
>UniRef50_Q6R1Y3 Cluster: Src family kinase; n=6; Fungi/Metazoa
group|Rep: Src family kinase - Asterina miniata (Bat
star) (Patiria miniata)
Length = 563
Score = 52.0 bits (119), Expect = 2e-05
Identities = 32/76 (42%), Positives = 41/76 (53%), Gaps = 6/76 (7%)
Frame = +1
Query: 295 NWFHGKISRESAEKLLKEEGED-GVFLVRESNTSPGDYVLSVLHQG-----QVVHYQIRR 456
+WF K++R+ AEK L+ G G FL+R S TSPG Y LSVL V HY+IR
Sbjct: 182 DWFFEKMTRKEAEKQLQLAGNSRGTFLIRGSETSPGAYSLSVLDHDDARGFNVKHYRIRT 241
Query: 457 HGEDAFFSIEEHTTVH 504
D ++ I T H
Sbjct: 242 LDNDGYY-ISTRITFH 256
>UniRef50_O97034 Cluster: PLC-gammaS; n=1; Ephydatia
fluviatilis|Rep: PLC-gammaS - Ephydatia fluviatilis
Length = 1283
Score = 52.0 bits (119), Expect = 2e-05
Identities = 28/59 (47%), Positives = 37/59 (62%), Gaps = 3/59 (5%)
Frame = +1
Query: 298 WFHGKIS--RESAEKLLKEEGE-DGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGE 465
WFHGK++ R +AEKLL + + +G FLVRES T GDY LS + G+ H +I E
Sbjct: 544 WFHGKLAGGRVAAEKLLTDYKDVNGAFLVRESTTFTGDYSLSFVRDGKYNHCRIHTKSE 602
Score = 46.8 bits (106), Expect = 7e-04
Identities = 24/55 (43%), Positives = 34/55 (61%), Gaps = 4/55 (7%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVR--ESNTSPG--DYVLSVLHQGQVVHYQI 450
WFH +SR AE++LK+ DG FL+R E NT G +Y +S +G+V H +I
Sbjct: 655 WFHENLSRSEAEEMLKKVRMDGAFLIRPSEQNTKAGQKNYAISFRAEGKVKHCRI 709
>UniRef50_UPI000155BC71 Cluster: PREDICTED: similar to inositol
polyphosphate 5- phosphatase; n=1; Ornithorhynchus
anatinus|Rep: PREDICTED: similar to inositol
polyphosphate 5- phosphatase - Ornithorhynchus anatinus
Length = 1019
Score = 51.6 bits (118), Expect = 2e-05
Identities = 25/59 (42%), Positives = 35/59 (59%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAF 474
W HG I+R AE+LL + G+DG FLVR S + Y L VL+ V Y+I + ++ F
Sbjct: 5 WNHGNITRSKAEELLSKTGKDGSFLVRASESISRAYALCVLYHNCVYTYRILPNDDEKF 63
>UniRef50_UPI00003A9BD4 Cluster: PREDICTED: similar to SH2
domain-containing molecule EAT2; n=1; Gallus gallus|Rep:
PREDICTED: similar to SH2 domain-containing molecule
EAT2 - Gallus gallus
Length = 134
Score = 51.6 bits (118), Expect = 2e-05
Identities = 25/59 (42%), Positives = 38/59 (64%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAF 474
+FHGKISR++ E LL ++G++G +L+RES T G L VL + + Y+I R E +
Sbjct: 5 FFHGKISRKACEDLLCKKGKNGSYLIRESETVAGALCLCVLFEKVIYTYRIFREYEGCY 63
>UniRef50_Q8AVM4 Cluster: Sh2d3c-prov protein; n=5;
Euteleostomi|Rep: Sh2d3c-prov protein - Xenopus laevis
(African clawed frog)
Length = 676
Score = 51.6 bits (118), Expect = 2e-05
Identities = 25/65 (38%), Positives = 43/65 (66%), Gaps = 2/65 (3%)
Frame = +1
Query: 268 LRMNREDNVN--WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVH 441
L++N D + W+HG+I RE +E L++ G+ FL+R+S TS GDYVL+ + + +H
Sbjct: 27 LKLNSSDPRSHAWYHGRIPREVSESLVQRNGD---FLIRDSLTSLGDYVLTCRWKNESLH 83
Query: 442 YQIRR 456
++I +
Sbjct: 84 FKINK 88
>UniRef50_Q4SYA1 Cluster: Chromosome undetermined SCAF12132, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF12132, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 422
Score = 51.6 bits (118), Expect = 2e-05
Identities = 25/47 (53%), Positives = 32/47 (68%), Gaps = 2/47 (4%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDG--VFLVRESNTSPGDYVLSVLHQGQ 432
WFHG ISR A L++ G +G VFLVR+S T GDYVL+ +QG+
Sbjct: 135 WFHGPISRVKAAHLVQSSGPEGHGVFLVRQSETRRGDYVLTFNYQGK 181
>UniRef50_A2IB48 Cluster: Phospholipase C gamma; n=5; Eumetazoa|Rep:
Phospholipase C gamma - Chaetopterus pergamentaceus
Length = 1322
Score = 51.6 bits (118), Expect = 2e-05
Identities = 38/109 (34%), Positives = 55/109 (50%), Gaps = 11/109 (10%)
Frame = +1
Query: 298 WFHGKIS--RESAEKLLKEEGE--DGVFLVRESNTSPGDYVLSVLHQGQVVHYQIR---R 456
WFHGK+ R AE LLKE DG FLVRES+T GD+ LS + V H +IR
Sbjct: 560 WFHGKLEGGRRKAEDLLKEYSYLGDGTFLVRESDTFVGDFSLSFWRKDSVNHCRIRSKQE 619
Query: 457 HGEDAFFSIEE--HTTVHGWILLYNITVVIQMDL--LLGCPLSVKENHH 591
G+ ++ I+ +++ I Y + D +L P+ ++HH
Sbjct: 620 RGQTKYYLIDNLAFDSLYSLITHYQKYPLRSQDFQQILKEPVPQPQSHH 668
Score = 48.8 bits (111), Expect = 2e-04
Identities = 20/55 (36%), Positives = 31/55 (56%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHG 462
W+H K+ R AE +LK DG FLVR++ Y +S +G++ H I++ G
Sbjct: 672 WYHEKLDRTRAEDMLKRIPSDGAFLVRQNGVDTNSYAISFRAEGKIKHCIIKQEG 726
>UniRef50_P19174 Cluster: 1-phosphatidylinositol-4,5-bisphosphate
phosphodiesterase gamma-1; n=65; Eumetazoa|Rep:
1-phosphatidylinositol-4,5-bisphosphate
phosphodiesterase gamma-1 - Homo sapiens (Human)
Length = 1290
Score = 51.6 bits (118), Expect = 2e-05
Identities = 23/82 (28%), Positives = 41/82 (50%)
Frame = +1
Query: 277 NREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
N ++ W+H ++R AE +L DG FLVR+ N P Y +S +G++ H ++++
Sbjct: 661 NAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRN-EPNSYAISFRAEGKIKHCRVQQ 719
Query: 457 HGEDAFFSIEEHTTVHGWILLY 522
G+ E ++ I Y
Sbjct: 720 EGQTVMLGNSEFDSLVDLISYY 741
Score = 48.4 bits (110), Expect = 2e-04
Identities = 30/64 (46%), Positives = 34/64 (53%), Gaps = 10/64 (15%)
Frame = +1
Query: 289 NVNWFHGKIS-----RESAEKLLKEE-----GEDGVFLVRESNTSPGDYVLSVLHQGQVV 438
N WFHGK+ R AE+LL E DG FLVRES T GDY LS G+V
Sbjct: 547 NEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQ 606
Query: 439 HYQI 450
H +I
Sbjct: 607 HCRI 610
>UniRef50_UPI0000F1FB23 Cluster: PREDICTED: similar to tyrosine
protein kinase BTK; n=1; Danio rerio|Rep: PREDICTED:
similar to tyrosine protein kinase BTK - Danio rerio
Length = 596
Score = 51.2 bits (117), Expect = 3e-05
Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 6/85 (7%)
Frame = +1
Query: 256 NSFLLRMNREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQ--- 426
N + +N + +W+ I+R AE LLK E +DG FLVR+S G Y +SV +
Sbjct: 226 NYIVQALNGLEKYDWYCKNINRSQAENLLKTENKDGGFLVRDSGKFTGKYTVSVFTKAGG 285
Query: 427 ---GQVVHYQIRRHGEDAFFSIEEH 492
G HY I + F+ E+H
Sbjct: 286 ETSGSCRHYNILLTADGQFYLAEKH 310
>UniRef50_UPI0000E811F8 Cluster: PREDICTED: similar to SH2D3C
protein; n=1; Gallus gallus|Rep: PREDICTED: similar to
SH2D3C protein - Gallus gallus
Length = 603
Score = 51.2 bits (117), Expect = 3e-05
Identities = 25/79 (31%), Positives = 46/79 (58%)
Frame = +1
Query: 220 DNNHDVIHIT*ENSFLLRMNREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPG 399
D++ + +H E L + W+HG+I RE +E L++ G+ F++R+S TS G
Sbjct: 37 DSSPEKLHKELEEELKLSSTDLRSHAWYHGRIPREVSESLVQRNGD---FIIRDSLTSVG 93
Query: 400 DYVLSVLHQGQVVHYQIRR 456
DYVL+ + + +H++I +
Sbjct: 94 DYVLTCRWRNEPLHFKINK 112
>UniRef50_Q4S131 Cluster: Chromosome 1 SCAF14770, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 1 SCAF14770, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 789
Score = 51.2 bits (117), Expect = 3e-05
Identities = 23/51 (45%), Positives = 31/51 (60%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
W+H I+R AE LL + DG FL+R+S + G Y L VL+Q V Y+I
Sbjct: 1 WYHSNITRSKAEDLLSKAARDGSFLIRDSESIQGAYALCVLYQKCVYTYRI 51
>UniRef50_Q4RUN4 Cluster: Chromosome 12 SCAF14993, whole genome
shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
Chromosome 12 SCAF14993, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1136
Score = 51.2 bits (117), Expect = 3e-05
Identities = 23/52 (44%), Positives = 34/52 (65%), Gaps = 1/52 (1%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVV-HYQI 450
W+HGK+ R AE+ L++ G +L+RES+ PG +VLS L VV H++I
Sbjct: 185 WYHGKLDRTIAEERLRQARNPGSYLIRESDRRPGSFVLSFLSMTNVVNHFRI 236
Score = 41.5 bits (93), Expect = 0.025
Identities = 18/38 (47%), Positives = 25/38 (65%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVL 411
W+HG I+++ A LL G+ FLVR S+ +PGDY L
Sbjct: 359 WYHGHITKKEAYNLLMTVGQVCSFLVRPSDNTPGDYSL 396
>UniRef50_Q8IR23 Cluster: CG9209-PA, isoform A; n=6;
Endopterygota|Rep: CG9209-PA, isoform A - Drosophila
melanogaster (Fruit fly)
Length = 954
Score = 51.2 bits (117), Expect = 3e-05
Identities = 22/51 (43%), Positives = 33/51 (64%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
W+HG++ R SAE L+ + G +LVRES+ PG YVLS + + H++I
Sbjct: 84 WYHGRLDRYSAESRLRGSSKLGSYLVRESDRKPGSYVLSYYGRTGINHFRI 134
Score = 42.3 bits (95), Expect = 0.015
Identities = 21/55 (38%), Positives = 30/55 (54%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHG 462
WFH ++ A +L + G G FLVR S+ SPGDY L Q+ ++I + G
Sbjct: 253 WFHPNCTKNEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKG 306
>UniRef50_Q21055 Cluster: Protein tyrosine phosphatase protein 2;
n=2; Caenorhabditis|Rep: Protein tyrosine phosphatase
protein 2 - Caenorhabditis elegans
Length = 668
Score = 51.2 bits (117), Expect = 3e-05
Identities = 28/76 (36%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAFF 477
W+HG + SA KLL+ E ++G +L+R S PG V+S +GQVVH I + F
Sbjct: 134 WWHGNLPASSANKLLQTE-KNGTYLLRASQHIPGALVISAKTEGQVVHLTIYQDPSTGRF 192
Query: 478 SIEEHTT--VHGWILL 519
+I+ T W+L+
Sbjct: 193 NIDGDRTKFQSAWLLI 208
Score = 50.4 bits (115), Expect = 6e-05
Identities = 23/67 (34%), Positives = 44/67 (65%), Gaps = 1/67 (1%)
Frame = +1
Query: 301 FHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSV-LHQGQVVHYQIRRHGEDAFF 477
F+ +++ E AE+LLKE GEDG FL+R S ++P ++ +SV + + +++H ++ ++ D
Sbjct: 11 FYYRVNGEKAEELLKEYGEDGDFLLRYSESNPQNFSISVRVAEDKILHIKVTKYESDMLS 70
Query: 478 SIEEHTT 498
E+ T
Sbjct: 71 IFEDERT 77
>UniRef50_O44235 Cluster: HrSH2 protein; n=1; Halocynthia
roretzi|Rep: HrSH2 protein - Halocynthia roretzi (Sea
squirt)
Length = 867
Score = 51.2 bits (117), Expect = 3e-05
Identities = 27/79 (34%), Positives = 48/79 (60%), Gaps = 2/79 (2%)
Frame = +1
Query: 226 NHDVIHIT*ENSFLLRMNRED--NVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPG 399
+ DV+ EN LR ++ D + WFHG++ R+ AE L++ EG+ FL+RES + G
Sbjct: 27 SQDVLRKELENE--LRSDKSDIRSYAWFHGRMPRDIAEDLIRREGD---FLIRESVNNAG 81
Query: 400 DYVLSVLHQGQVVHYQIRR 456
++VL+ ++ H++I +
Sbjct: 82 EFVLTCKYKSATYHFKINK 100
>UniRef50_P50745 Cluster: SH2B adapter protein 3; n=3; Rattus
norvegicus|Rep: SH2B adapter protein 3 - Rattus
norvegicus (Rat)
Length = 368
Score = 51.2 bits (117), Expect = 3e-05
Identities = 25/53 (47%), Positives = 36/53 (67%), Gaps = 2/53 (3%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGED--GVFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
WFHG ISR A +L++ +G D GVFLVR+S + G+YVL+ QG+ H ++
Sbjct: 119 WFHGPISRVRAAQLVQLQGPDAHGVFLVRQSESRRGEYVLTFNLQGRAKHLRL 171
>UniRef50_O14492 Cluster: SH2B adapter protein 2; n=7;
Tetrapoda|Rep: SH2B adapter protein 2 - Homo sapiens
(Human)
Length = 632
Score = 51.2 bits (117), Expect = 3e-05
Identities = 23/57 (40%), Positives = 36/57 (63%), Gaps = 2/57 (3%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEG--EDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHG 462
WFHG +SR A +L+ G G+F++R+S T PG+YVL+ QG+ H ++ +G
Sbjct: 417 WFHGTLSRVKAAQLVLAGGPRNHGLFVIRQSETRPGEYVLTFNFQGKAKHLRLSLNG 473
>UniRef50_O43639 Cluster: Cytoplasmic protein NCK2; n=54;
Euteleostomi|Rep: Cytoplasmic protein NCK2 - Homo
sapiens (Human)
Length = 380
Score = 51.2 bits (117), Expect = 3e-05
Identities = 19/52 (36%), Positives = 35/52 (67%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIR 453
W++G ++R AE L E G +G FL+R+S +SP D+ +S+ G+ H++++
Sbjct: 285 WYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQ 336
>UniRef50_P08630 Cluster: Tyrosine-protein kinase Btk29A; n=10;
Endopterygota|Rep: Tyrosine-protein kinase Btk29A -
Drosophila melanogaster (Fruit fly)
Length = 786
Score = 51.2 bits (117), Expect = 3e-05
Identities = 26/72 (36%), Positives = 44/72 (61%), Gaps = 3/72 (4%)
Frame = +1
Query: 286 DNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSV---LHQGQVVHYQIRR 456
+ W+ G +SR+ AE LLK+ ++G F+VR+S+T G Y LS+ + Q V HY I++
Sbjct: 406 ERYEWYVGDMSRQRAESLLKQGDKEGCFVVRKSSTK-GLYTLSLHTKVPQSHVKHYHIKQ 464
Query: 457 HGEDAFFSIEEH 492
+ ++ E+H
Sbjct: 465 NARCEYYLSEKH 476
>UniRef50_P51813 Cluster: Cytoplasmic tyrosine-protein kinase BMX;
n=36; Euteleostomi|Rep: Cytoplasmic tyrosine-protein
kinase BMX - Homo sapiens (Human)
Length = 675
Score = 51.2 bits (117), Expect = 3e-05
Identities = 25/75 (33%), Positives = 44/75 (58%), Gaps = 6/75 (8%)
Frame = +1
Query: 286 DNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVL------HQGQVVHYQ 447
D+ +WF G ISR +E+LL+++G++G F+VR S + G Y +S+ +G V HY
Sbjct: 292 DDYDWFAGNISRSQSEQLLRQKGKEGAFMVRNS-SQVGMYTVSLFSKAVNDKKGTVKHYH 350
Query: 448 IRRHGEDAFFSIEEH 492
+ + E+ + E +
Sbjct: 351 VHTNAENKLYLAENY 365
>UniRef50_UPI0000E48B80 Cluster: PREDICTED: hypothetical protein; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 936
Score = 50.8 bits (116), Expect = 4e-05
Identities = 24/65 (36%), Positives = 40/65 (61%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAFF 477
W++G++ R+ E L+ +G+ +LVR+S+ GD +LSVL+ +V HY I+ +D F
Sbjct: 836 WYYGRMLRQECEYLMLSQGKSKQYLVRDSSHRAGDLMLSVLYGSKVHHYVIQT-TDDKKF 894
Query: 478 SIEEH 492
I H
Sbjct: 895 QIAHH 899
>UniRef50_Q567F1 Cluster: Zgc:112091; n=2; Euteleostomi|Rep:
Zgc:112091 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 284
Score = 50.8 bits (116), Expect = 4e-05
Identities = 27/82 (32%), Positives = 45/82 (54%), Gaps = 1/82 (1%)
Frame = +1
Query: 295 NWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAF 474
+WF SR SAE+ L E G FL+R S +SPGD+ +SV H V H+++ + +
Sbjct: 57 SWFKESASRGSAEETLMSR-EVGAFLIRGSQSSPGDFSISVRHDYDVQHFKVMKDKSGHY 115
Query: 475 FS-IEEHTTVHGWILLYNITVV 537
+ E+ T+++ + Y T +
Sbjct: 116 YLWTEKFTSLNKLVDFYKTTSI 137
>UniRef50_Q17BH3 Cluster: Putative uncharacterized protein; n=1; Aedes
aegypti|Rep: Putative uncharacterized protein - Aedes
aegypti (Yellowfever mosquito)
Length = 1044
Score = 50.8 bits (116), Expect = 4e-05
Identities = 27/64 (42%), Positives = 37/64 (57%)
Frame = +1
Query: 286 DNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGE 465
D W+HG ISR AEK+L+ GE G FLVR S ++ DY L++ +H +I+R E
Sbjct: 939 DRQGWYHGSISRIDAEKILRPLGE-GSFLVRNSESTRQDYSLTLKSAKGFMHMRIQRDHE 997
Query: 466 DAFF 477
F
Sbjct: 998 TGQF 1001
>UniRef50_UPI00015B5D64 Cluster: PREDICTED: similar to LD41184p;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
LD41184p - Nasonia vitripennis
Length = 858
Score = 50.4 bits (115), Expect = 6e-05
Identities = 22/53 (41%), Positives = 32/53 (60%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
W+HG + E DG FLVR+ ++ PG+YVLSV H+GQ +H+ I +
Sbjct: 168 WYHGSSLPGGRKGAEAEIPNDGDFLVRDCSSQPGNYVLSVRHKGQALHFVINK 220
>UniRef50_Q4T6N5 Cluster: Chromosome 9 SCAF8684, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 9 SCAF8684, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 966
Score = 50.4 bits (115), Expect = 6e-05
Identities = 22/82 (26%), Positives = 40/82 (48%)
Frame = +1
Query: 277 NREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
N ++ W+H +SR AE +L DG FLVR+ P + +S +G++ H ++++
Sbjct: 740 NAHESKEWYHANLSRSQAENMLMRVPRDGAFLVRK-RAEPNSFAISFRAEGKIKHCRVQQ 798
Query: 457 HGEDAFFSIEEHTTVHGWILLY 522
G+ E ++ I Y
Sbjct: 799 EGQTVVLGTSEFDSLVDLISYY 820
Score = 49.6 bits (113), Expect = 1e-04
Identities = 31/74 (41%), Positives = 38/74 (51%), Gaps = 10/74 (13%)
Frame = +1
Query: 274 MNREDNVNWFHGKIS-----RESAEKLLKEE-----GEDGVFLVRESNTSPGDYVLSVLH 423
M++ WFHGK+ R+ AE+LL E DG FLVRES T GDY LS
Sbjct: 621 MDQHVTEKWFHGKLGAGRDGRQIAERLLSEYCMETGAPDGSFLVRESETFVGDYTLSFWR 680
Query: 424 QGQVVHYQIRRHGE 465
G+V H +I E
Sbjct: 681 SGRVQHCRIHSRQE 694
>UniRef50_Q9VXH3 Cluster: CG4200-PA; n=5; Drosophila|Rep: CG4200-PA
- Drosophila melanogaster (Fruit fly)
Length = 1236
Score = 50.4 bits (115), Expect = 6e-05
Identities = 36/100 (36%), Positives = 55/100 (55%), Gaps = 6/100 (6%)
Frame = +1
Query: 295 NWFHGKIS--RESAEKLLKEEGE--DGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHG 462
NWFHGK+ R+ A+ LLK+ DG FLVRES T GDY LS + + H +I+
Sbjct: 588 NWFHGKLEGGRKEADDLLKKYKHFGDGTFLVRESATFVGDYSLSFWRRNRPNHCRIKLKH 647
Query: 463 EDAFFSIEEHTTVHGWIL--LYNITVVIQMDLLLGCPLSV 576
E+ SI ++ V ++ LY++ V + ++L S+
Sbjct: 648 ENG--SI-KYYLVENFVFDSLYSLIVYYRKNMLRSSEFSI 684
>UniRef50_Q9VPU1 Cluster: CG3727-PB, isoform B; n=9;
Endopterygota|Rep: CG3727-PB, isoform B - Drosophila
melanogaster (Fruit fly)
Length = 548
Score = 50.4 bits (115), Expect = 6e-05
Identities = 22/63 (34%), Positives = 38/63 (60%)
Frame = +1
Query: 295 NWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAF 474
+W++G I+R + +L G DG FL+R+S T+ GDY +S+ G+ H+++ H E
Sbjct: 447 SWYYGAITRSQCDTVLNGHGHDGDFLIRDSETNMGDYSVSLKAPGRNKHFRV--HVEQNM 504
Query: 475 FSI 483
+ I
Sbjct: 505 YCI 507
>UniRef50_Q9TYT3 Cluster: Putative uncharacterized protein; n=5;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 316
Score = 50.4 bits (115), Expect = 6e-05
Identities = 23/39 (58%), Positives = 30/39 (76%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLS 414
W+HG +SRE A+ LLK EG+ FLVR+S+ +PG YVLS
Sbjct: 211 WYHGNLSREDAQALLKTEGD---FLVRQSDHTPGKYVLS 246
>UniRef50_UPI0000ECA6D9 Cluster: SH2B adapter protein 3
(Lymphocyte-specific adapter protein Lnk) (Signal
transduction protein Lnk) (Lymphocyte adapter protein).;
n=1; Gallus gallus|Rep: SH2B adapter protein 3
(Lymphocyte-specific adapter protein Lnk) (Signal
transduction protein Lnk) (Lymphocyte adapter protein).
- Gallus gallus
Length = 506
Score = 50.0 bits (114), Expect = 7e-05
Identities = 25/53 (47%), Positives = 35/53 (66%), Gaps = 2/53 (3%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDG--VFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
WFHG ISR A +L++ G +G VFLVR+S T G+YVL+ QG+ H ++
Sbjct: 388 WFHGPISRVKAAQLVQLGGLEGHGVFLVRQSETRRGEYVLTFNFQGRAKHLRL 440
>UniRef50_Q5RJ36 Cluster: Novel protein similar to vertebrate
lymphocyte adaptor protein; n=2; Danio rerio|Rep: Novel
protein similar to vertebrate lymphocyte adaptor protein
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 279
Score = 50.0 bits (114), Expect = 7e-05
Identities = 25/54 (46%), Positives = 34/54 (62%), Gaps = 2/54 (3%)
Frame = +1
Query: 295 NWFHGKISRESAEKLLKEEGEDGV--FLVRESNTSPGDYVLSVLHQGQVVHYQI 450
+WFHG ISR A L++ G G FLVR+S T GDYVL+ +QG+ H ++
Sbjct: 118 SWFHGPISRVRAAYLVQHAGVSGHGNFLVRQSETRRGDYVLTFNYQGRAKHLRL 171
>UniRef50_P07947 Cluster: Proto-oncogene tyrosine-protein kinase
Yes; n=422; root|Rep: Proto-oncogene tyrosine-protein
kinase Yes - Homo sapiens (Human)
Length = 543
Score = 50.0 bits (114), Expect = 7e-05
Identities = 26/66 (39%), Positives = 38/66 (57%), Gaps = 6/66 (9%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGED-GVFLVRESNTSPGDYVLSV-----LHQGQVVHYQIRRH 459
W+ GK+ R+ AE+LL G G+FLVRES T+ G Y LS+ + V HY+IR+
Sbjct: 158 WYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEIRGDNVKHYKIRKL 217
Query: 460 GEDAFF 477
++
Sbjct: 218 DNGGYY 223
>UniRef50_UPI000051A29D Cluster: PREDICTED: similar to SHC-adaptor
protein CG3715-PA; n=2; Apocrita|Rep: PREDICTED: similar
to SHC-adaptor protein CG3715-PA - Apis mellifera
Length = 443
Score = 49.6 bits (113), Expect = 1e-04
Identities = 23/48 (47%), Positives = 30/48 (62%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVH 441
WFHG +SR AE +L +G+ FLVRES SPG YVL+ ++ H
Sbjct: 346 WFHGSVSRAEAESMLTRDGD---FLVRESQGSPGQYVLTGMNNNTPKH 390
>UniRef50_Q5BWZ4 Cluster: SJCHGC04657 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC04657 protein - Schistosoma
japonicum (Blood fluke)
Length = 153
Score = 49.6 bits (113), Expect = 1e-04
Identities = 24/59 (40%), Positives = 36/59 (61%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAF 474
WFH ++R AE+L++ E E G FLVR S T P D+ L++ H+ +H +I R+ F
Sbjct: 55 WFHPSLTRSEAEELIRNEPE-GSFLVRPSETCPNDFSLTIKHK-TFLHMKITRNNAGQF 111
>UniRef50_UPI0000E478D2 Cluster: PREDICTED: similar to SH2/SH3
adaptor Grb2; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to SH2/SH3 adaptor Grb2 -
Strongylocentrotus purpuratus
Length = 241
Score = 49.2 bits (112), Expect = 1e-04
Identities = 23/53 (43%), Positives = 36/53 (67%), Gaps = 2/53 (3%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSP--GDYVLSVLHQGQVVHYQI 450
W+ GKISR+ AE+ L DG F++R+S ++P G++ LSV + QV H++I
Sbjct: 62 WYVGKISRKVAEEYLMSMPSDGAFMIRDSESNPDSGNFSLSVKFRDQVQHFKI 114
>UniRef50_UPI00015A3F46 Cluster: UPI00015A3F46 related cluster; n=4;
Euteleostomi|Rep: UPI00015A3F46 UniRef100 entry - Danio
rerio
Length = 217
Score = 49.2 bits (112), Expect = 1e-04
Identities = 22/53 (41%), Positives = 34/53 (64%), Gaps = 2/53 (3%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEG--EDGVFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
WFHG +SR A +L+ G G+F++R+S T PG+YVL+ QG+ H ++
Sbjct: 117 WFHGTLSRVRAAQLVLAGGARSHGLFVIRQSETRPGEYVLTFNFQGKAKHLRL 169
>UniRef50_Q6GP30 Cluster: MGC80721 protein; n=1; Xenopus laevis|Rep:
MGC80721 protein - Xenopus laevis (African clawed frog)
Length = 508
Score = 49.2 bits (112), Expect = 1e-04
Identities = 25/55 (45%), Positives = 35/55 (63%), Gaps = 2/55 (3%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRES--NTSPGDYVLSVLHQGQVVHYQIRR 456
W+ G ISR AE L+ +DG FLVR S +T+ YVL VL++ +V + QIR+
Sbjct: 395 WYTGNISRSEAETALRSINQDGTFLVRNSSKSTASHPYVLMVLYRNKVYNIQIRQ 449
>UniRef50_Q5U3P8 Cluster: Zgc:101809; n=5; Danio rerio|Rep:
Zgc:101809 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 501
Score = 49.2 bits (112), Expect = 1e-04
Identities = 27/61 (44%), Positives = 39/61 (63%), Gaps = 2/61 (3%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESN--TSPGDYVLSVLHQGQVVHYQIRRHGEDA 471
W+ G+I+R AE L+ DG FLVR+S+ +S Y L VL+Q +V + QIRR+ +D
Sbjct: 391 WYLGQITRGEAESCLRRVNRDGTFLVRDSSNRSSNQPYTLVVLYQDKVYNIQIRRN-QDR 449
Query: 472 F 474
F
Sbjct: 450 F 450
>UniRef50_Q9NRF3 Cluster: SH2B adaptor protein 1; n=33;
Mammalia|Rep: SH2B adaptor protein 1 - Homo sapiens
(Human)
Length = 756
Score = 49.2 bits (112), Expect = 1e-04
Identities = 25/58 (43%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKE--EGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGE 465
WFHG +SR A +L+ G GVFLVR+S T G+YVL+ QG+ H ++ + E
Sbjct: 527 WFHGMLSRLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNEE 584
>UniRef50_UPI0000E4625F Cluster: PREDICTED: hypothetical protein;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 520
Score = 48.8 bits (111), Expect = 2e-04
Identities = 24/51 (47%), Positives = 30/51 (58%)
Frame = +1
Query: 289 NVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVH 441
N WFHG +SR+ E LL +G+ FLVRES T+ YVLS + G H
Sbjct: 420 NEEWFHGPMSRKEGEPLLSNDGD---FLVRESTTAKDQYVLSGMQNGTPKH 467
>UniRef50_UPI0000D8C686 Cluster: Breast cancer anti-estrogen
resistance protein 3 (SH2 domain- containing protein 3B)
(Novel SH2-containing protein 2).; n=1; Danio rerio|Rep:
Breast cancer anti-estrogen resistance protein 3 (SH2
domain- containing protein 3B) (Novel SH2-containing
protein 2). - Danio rerio
Length = 628
Score = 48.8 bits (111), Expect = 2e-04
Identities = 21/53 (39%), Positives = 36/53 (67%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
W+HG I R+ AE L++ +G+ FL+R+S +SPG+YVL+ + H++I +
Sbjct: 46 WYHGAIPRQVAENLVQRDGD---FLIRDSLSSPGNYVLTCQWKNSPQHFKINK 95
>UniRef50_P52757 Cluster: Beta-chimaerin; n=13; Amniota|Rep:
Beta-chimaerin - Homo sapiens (Human)
Length = 468
Score = 48.8 bits (111), Expect = 2e-04
Identities = 32/79 (40%), Positives = 46/79 (58%), Gaps = 5/79 (6%)
Frame = +1
Query: 301 FHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQI---RRH--GE 465
FHG ISRE A++LL G +G +++RES PG Y L++ Q ++Y++ +H GE
Sbjct: 60 FHGIISREQADELLG--GVEGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGE 117
Query: 466 DAFFSIEEHTTVHGWILLY 522
F SI + T G I LY
Sbjct: 118 KRFESIHDLVT-DGLITLY 135
>UniRef50_O75815 Cluster: Breast cancer anti-estrogen resistance
protein 3; n=34; Euteleostomi|Rep: Breast cancer
anti-estrogen resistance protein 3 - Homo sapiens
(Human)
Length = 825
Score = 48.8 bits (111), Expect = 2e-04
Identities = 21/53 (39%), Positives = 37/53 (69%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
W+HG+I R+ +E L++ +G+ FLVR+S +SPG++VL+ + H++I R
Sbjct: 154 WYHGRIPRQVSENLVQRDGD---FLVRDSLSSPGNFVLTCQWKNLAQHFKINR 203
>UniRef50_UPI0000D57904 Cluster: PREDICTED: similar to CG9098-PA,
isoform A, partial; n=1; Tribolium castaneum|Rep:
PREDICTED: similar to CG9098-PA, isoform A, partial -
Tribolium castaneum
Length = 851
Score = 48.4 bits (110), Expect = 2e-04
Identities = 22/53 (41%), Positives = 34/53 (64%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
W+HG I R AE +++EEG FLVR+ + PG+YVL+ + Q +H+ I +
Sbjct: 176 WYHGAIPRSRAEDIVREEGG---FLVRDCTSQPGNYVLTCRTKTQPLHFVINK 225
>UniRef50_Q4S6Q5 Cluster: Chromosome undetermined SCAF14724, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF14724,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 803
Score = 48.4 bits (110), Expect = 2e-04
Identities = 21/53 (39%), Positives = 35/53 (66%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
W+HG I R+ AE L++ +G+ FL+R+S +SPG YVL+ + H++I +
Sbjct: 36 WYHGAIPRQVAENLVQRDGD---FLIRDSLSSPGSYVLTSQWRNTAQHFKINK 85
>UniRef50_Q4RUJ4 Cluster: Chromosome 1 SCAF14995, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 1 SCAF14995, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 666
Score = 48.4 bits (110), Expect = 2e-04
Identities = 23/48 (47%), Positives = 32/48 (66%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVH 441
W+H ++SR AE+LL +G+ FLVRES T+ G YVL+ +H G H
Sbjct: 571 WYHSRMSRRDAERLLIRDGD---FLVRESTTNLGQYVLTGMHCGLPKH 615
>UniRef50_A2RUZ0 Cluster: Zgc:158474 protein; n=4; Euteleostomi|Rep:
Zgc:158474 protein - Danio rerio (Zebrafish)
(Brachydanio rerio)
Length = 906
Score = 48.4 bits (110), Expect = 2e-04
Identities = 24/53 (45%), Positives = 33/53 (62%), Gaps = 2/53 (3%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEG--EDGVFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
WFHG +SR A +L+ G GVFLVR+S T G+YVL+ QG+ H ++
Sbjct: 715 WFHGTLSRLKAAQLVLAGGMASHGVFLVRQSETRRGEYVLTFNFQGKAKHLRL 767
>UniRef50_Q7QGU0 Cluster: ENSANGP00000018199; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000018199 - Anopheles gambiae
str. PEST
Length = 710
Score = 48.4 bits (110), Expect = 2e-04
Identities = 25/64 (39%), Positives = 36/64 (56%)
Frame = +1
Query: 286 DNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGE 465
D W+HG ISR AEK+L+ E G FLVR S ++ DY L++ +H +I+R +
Sbjct: 605 DRQGWYHGSISRIDAEKILRPLSE-GSFLVRNSESTRQDYSLTLKSAKGFMHMRIQRDAD 663
Query: 466 DAFF 477
F
Sbjct: 664 SGQF 667
>UniRef50_Q17AB7 Cluster: Putative uncharacterized protein; n=1;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 724
Score = 48.4 bits (110), Expect = 2e-04
Identities = 20/53 (37%), Positives = 36/53 (67%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
W+HG I R+ AE++++ +G+ FLVR+ + PG+YVL+ +G +H+ I +
Sbjct: 25 WYHGPIPRQRAEEIVQRDGD---FLVRDCVSQPGNYVLTCKTKGPTLHFVINK 74
>UniRef50_UPI0000F1FADE Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 324
Score = 48.0 bits (109), Expect = 3e-04
Identities = 27/64 (42%), Positives = 39/64 (60%), Gaps = 2/64 (3%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGD--YVLSVLHQGQVVHYQIRRHGEDA 471
W+ G+ISR AE L++ +DG FLVR+S+ + Y L VLHQ +V + QIR G
Sbjct: 212 WYVGQISRGEAEVSLRKVKKDGTFLVRDSSKGCEEQPYTLMVLHQQKVYNIQIRFLGNKD 271
Query: 472 FFSI 483
+S+
Sbjct: 272 GYSL 275
>UniRef50_UPI0000DB7594 Cluster: PREDICTED: similar to CG9098-PA,
isoform A; n=1; Apis mellifera|Rep: PREDICTED: similar
to CG9098-PA, isoform A - Apis mellifera
Length = 797
Score = 48.0 bits (109), Expect = 3e-04
Identities = 22/53 (41%), Positives = 31/53 (58%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
W+HG R + E DG FLVR+ + PG+YVL+V +GQ +H+ I R
Sbjct: 148 WYHGSTLRGGRKGAEAEVPNDGDFLVRDCASQPGNYVLTVRWKGQPLHFVINR 200
>UniRef50_UPI0000567EFA Cluster: UPI0000567EFA related cluster; n=2;
Danio rerio|Rep: UPI0000567EFA UniRef100 entry - Danio
rerio
Length = 486
Score = 48.0 bits (109), Expect = 3e-04
Identities = 27/64 (42%), Positives = 39/64 (60%), Gaps = 2/64 (3%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGD--YVLSVLHQGQVVHYQIRRHGEDA 471
W+ G+ISR AE L++ +DG FLVR+S+ + Y L VLHQ +V + QIR G
Sbjct: 374 WYVGQISRGEAEVSLRKVKKDGTFLVRDSSKGCEEQPYTLMVLHQQKVYNIQIRFLGNKD 433
Query: 472 FFSI 483
+S+
Sbjct: 434 GYSL 437
>UniRef50_Q17DJ2 Cluster: Signal transduction protein lnk-realted;
n=2; Endopterygota|Rep: Signal transduction protein
lnk-realted - Aedes aegypti (Yellowfever mosquito)
Length = 564
Score = 48.0 bits (109), Expect = 3e-04
Identities = 22/53 (41%), Positives = 33/53 (62%), Gaps = 2/53 (3%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEG--EDGVFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
WFHG ++R A +L+ G GVFLVR+S T G++VL+ QG+ H ++
Sbjct: 419 WFHGTLARSEAAQLVLHNGLSSHGVFLVRQSETRKGEFVLTFNFQGKAKHLRM 471
>UniRef50_Q13882 Cluster: Tyrosine-protein kinase 6; n=11;
Mammalia|Rep: Tyrosine-protein kinase 6 - Homo sapiens
(Human)
Length = 451
Score = 48.0 bits (109), Expect = 3e-04
Identities = 29/71 (40%), Positives = 38/71 (53%), Gaps = 2/71 (2%)
Frame = +1
Query: 256 NSFLLRMNREDNVNWFHGKISRESAEKLLKEEGE-DGVFLVRESNTSPGDYVLSVLHQGQ 432
+++L ++ WF G ISR A + L+ EG G FL+R S DYVLSV
Sbjct: 64 HNYLAERETVESEPWFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRDTQA 123
Query: 433 VVHYQI-RRHG 462
V HY+I RR G
Sbjct: 124 VRHYKIWRRAG 134
>UniRef50_Q9JID9 Cluster: SH2B adapter protein 2; n=16;
Euteleostomi|Rep: SH2B adapter protein 2 - Mus musculus
(Mouse)
Length = 621
Score = 47.6 bits (108), Expect = 4e-04
Identities = 22/57 (38%), Positives = 35/57 (61%), Gaps = 2/57 (3%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEG--EDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHG 462
WFHG +SR A +L+ G G+F++R+S T PG+ VL+ QG+ H ++ +G
Sbjct: 409 WFHGTLSRVKAAQLVLAGGPRSHGLFVIRQSETRPGECVLTFNFQGKAKHLRLSLNG 465
>UniRef50_Q13094 Cluster: Lymphocyte cytosolic protein 2; n=31;
Amniota|Rep: Lymphocyte cytosolic protein 2 - Homo
sapiens (Human)
Length = 533
Score = 47.6 bits (108), Expect = 4e-04
Identities = 25/65 (38%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Frame = +1
Query: 289 NVNWFHGKISRESAEKLLKEEGEDGVFLVRESN--TSPGDYVLSVLHQGQVVHYQIRRHG 462
N W+ I+R AE L++ +DG FLVR+S+ T+ YVL VL++ +V + QIR
Sbjct: 419 NEEWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQK 478
Query: 463 EDAFF 477
E +
Sbjct: 479 ESQVY 483
>UniRef50_Q08881 Cluster: Tyrosine-protein kinase ITK/TSK; n=18;
Euteleostomi|Rep: Tyrosine-protein kinase ITK/TSK - Homo
sapiens (Human)
Length = 620
Score = 47.6 bits (108), Expect = 4e-04
Identities = 22/53 (41%), Positives = 34/53 (64%)
Frame = +1
Query: 277 NREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQV 435
N + W++ ISR+ AEKLL + G++G F+VR+S T+ G Y +SV + V
Sbjct: 232 NNLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTA-GTYTVSVFTKAVV 283
>UniRef50_UPI0000E460CB Cluster: PREDICTED: similar to V-crk sarcoma
virus CT10 oncogene homolog (avian)-like; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
V-crk sarcoma virus CT10 oncogene homolog (avian)-like -
Strongylocentrotus purpuratus
Length = 305
Score = 47.2 bits (107), Expect = 5e-04
Identities = 29/90 (32%), Positives = 42/90 (46%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAFF 477
W G I+R + LL ++ G FLVR+S T PGD VL V +V HY I R +
Sbjct: 18 WHFGGITRSETDNLLIQK-RPGTFLVRDSRTCPGDSVLCVSENSKVSHYIITRKADQFVI 76
Query: 478 SIEEHTTVHGWILLYNITVVIQMDLLLGCP 567
+ +T+ + Y + L+ CP
Sbjct: 77 GDQIFSTLPDILNFYRGHYLDTTVLVEPCP 106
>UniRef50_UPI000065CF8C Cluster: SH2 domain-containing protein 3C
(Novel SH2-containing protein 3).; n=1; Takifugu
rubripes|Rep: SH2 domain-containing protein 3C (Novel
SH2-containing protein 3). - Takifugu rubripes
Length = 580
Score = 47.2 bits (107), Expect = 5e-04
Identities = 22/53 (41%), Positives = 34/53 (64%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
W+HG + E AE L+ GE FL+R+S ++ GD+VL+ Q + +H+ IRR
Sbjct: 36 WYHGPVPWEVAESLVVNHGE---FLIRDSRSNHGDFVLTCHWQQKTLHFLIRR 85
>UniRef50_Q910A2 Cluster: Spleen protein tyrosine kinase; n=2; Danio
rerio|Rep: Spleen protein tyrosine kinase - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 586
Score = 47.2 bits (107), Expect = 5e-04
Identities = 23/60 (38%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGE-DGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAF 474
+F G I+RE +E L++ G DG++L+R+S + G Y LS+ + Q HY I R D +
Sbjct: 10 YFFGNITREESEVYLQQGGSGDGLYLLRQSRSFLGGYALSLSYGRQFYHYTIERELNDTY 69
Score = 36.3 bits (80), Expect = 0.96
Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 4/66 (6%)
Frame = +1
Query: 265 LLRMNREDNVNWFHGKISRESAE-KLLKEEGEDGVF---LVRESNTSPGDYVLSVLHQGQ 432
L+ + + WFHGKI RE +E +LL +G R+ L +LH Q
Sbjct: 152 LIATTAHEKMPWFHGKIDREDSELRLLNTSRVNGQISNQTKRKQWQKRVPNALCLLHNNQ 211
Query: 433 VVHYQI 450
V+HY+I
Sbjct: 212 VMHYRI 217
>UniRef50_Q4SPM1 Cluster: Chromosome 16 SCAF14537, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 16 SCAF14537, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 636
Score = 47.2 bits (107), Expect = 5e-04
Identities = 23/64 (35%), Positives = 40/64 (62%), Gaps = 2/64 (3%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEG--EDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDA 471
WFHG +SR A +L+ G G+F++R+S T PG+YVL+ QG+ ++R+ ++
Sbjct: 411 WFHGTLSRVRAAQLVLAGGARSHGLFVIRQSETRPGEYVLTFNFQGKA---KVRQRRAES 467
Query: 472 FFSI 483
F++
Sbjct: 468 TFAV 471
>UniRef50_Q4S3B2 Cluster: Chromosome 4 SCAF14752, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 4
SCAF14752, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 721
Score = 47.2 bits (107), Expect = 5e-04
Identities = 22/53 (41%), Positives = 34/53 (64%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
W+HG I RE +E L+ G+ FLVR+S TS GD+VL+ + +H++I +
Sbjct: 37 WYHGHIPREVSETLVLRNGD---FLVRDSLTSVGDFVLTCRWDNEALHFRISK 86
>UniRef50_Q1KL02 Cluster: Chimerin 2; n=3; Tetraodontidae|Rep:
Chimerin 2 - Fugu rubripes (Japanese pufferfish)
(Takifugu rubripes)
Length = 676
Score = 47.2 bits (107), Expect = 5e-04
Identities = 27/81 (33%), Positives = 46/81 (56%)
Frame = +1
Query: 301 FHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAFFS 480
FHG+ISRE A++LL +G +L+RES PG + L++ Q ++Y++ G+ F
Sbjct: 7 FHGRISREYADELLATA--EGAYLIRESQRQPGSHTLALRFGHQTLNYRLFYDGKH-FVG 63
Query: 481 IEEHTTVHGWILLYNITVVIQ 543
+ +VH + IT+ I+
Sbjct: 64 EKRFESVHDLVTDALITLYIE 84
>UniRef50_Q573B4 Cluster: Proto-oncogene tyrosine-protein kinase
LCK; n=11; Coelomata|Rep: Proto-oncogene
tyrosine-protein kinase LCK - Homo sapiens (Human)
Length = 516
Score = 47.2 bits (107), Expect = 5e-04
Identities = 29/79 (36%), Positives = 44/79 (55%), Gaps = 6/79 (7%)
Frame = +1
Query: 259 SFLLRMNREDNVNWFHGKISRESAEKLLKEEGED-GVFLVRESNTSPGDYVLSV----LH 423
+F+ + N + WF +SR+ AE+ L G G FL+RES ++ G + LSV +
Sbjct: 172 NFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQN 231
Query: 424 QGQVV-HYQIRRHGEDAFF 477
QG+VV HY+IR F+
Sbjct: 232 QGEVVKHYKIRNLDNGGFY 250
>UniRef50_P43403 Cluster: Tyrosine-protein kinase ZAP-70; n=55;
Euteleostomi|Rep: Tyrosine-protein kinase ZAP-70 - Homo
sapiens (Human)
Length = 619
Score = 47.2 bits (107), Expect = 5e-04
Identities = 25/54 (46%), Positives = 35/54 (64%), Gaps = 1/54 (1%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEG-EDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
+F+G ISR AE+ LK G DG+FL+R+ S G YVLS++H + H+ I R
Sbjct: 10 FFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIER 63
Score = 40.7 bits (91), Expect = 0.045
Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 1/63 (1%)
Frame = +1
Query: 265 LLRMNREDNVNWFHGKISRESAE-KLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVH 441
L+ + + W+H ++RE AE KL DG FL+R G Y LS+++ V H
Sbjct: 152 LIATTAHERMPWYHSSLTREEAERKLYSGAQTDGKFLLR-PRKEQGTYALSLIYGKTVYH 210
Query: 442 YQI 450
Y I
Sbjct: 211 YLI 213
>UniRef50_Q6PE32 Cluster: Zgc:65942; n=2; Danio rerio|Rep: Zgc:65942
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 249
Score = 46.8 bits (106), Expect = 7e-04
Identities = 22/68 (32%), Positives = 39/68 (57%)
Frame = +1
Query: 295 NWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAF 474
+W+ SR+SA+ L + G F++R S +SPGD+ +SV H+ V H+++ R + +
Sbjct: 57 SWYKENTSRQSAQDELMCQ-PIGAFIIRGSQSSPGDFSISVRHENDVQHFKVMRDRQGRY 115
Query: 475 FSIEEHTT 498
+ E T
Sbjct: 116 YLWSEMFT 123
>UniRef50_Q95PW9 Cluster: Temporarily assigned gene name protein 22,
isoform a; n=3; Caenorhabditis|Rep: Temporarily assigned
gene name protein 22, isoform a - Caenorhabditis elegans
Length = 395
Score = 46.8 bits (106), Expect = 7e-04
Identities = 22/52 (42%), Positives = 35/52 (67%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIR 453
W+ G+ISRE AE LL G +G FLVR+S ++PGD +S+ + H++++
Sbjct: 301 WYFGRISRERAEDLLLH-GREGEFLVRDSESNPGDLSISMRGIERNKHFKVQ 351
>UniRef50_Q9BRG2 Cluster: SH2 domain-containing protein 3A; n=11;
Eutheria|Rep: SH2 domain-containing protein 3A - Homo
sapiens (Human)
Length = 576
Score = 46.8 bits (106), Expect = 7e-04
Identities = 21/53 (39%), Positives = 35/53 (66%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
W+HG +SR+ AE LL++ G+ FLVR S + G+ V+S +G +H+++ R
Sbjct: 15 WYHGLLSRQKAEALLQQNGD---FLVRASGSRGGNPVISCRWRGSALHFEVFR 64
>UniRef50_UPI0000F1F44E Cluster: PREDICTED: similar to
Src-like-adaptor 2; n=1; Danio rerio|Rep: PREDICTED:
similar to Src-like-adaptor 2 - Danio rerio
Length = 193
Score = 46.4 bits (105), Expect = 9e-04
Identities = 30/70 (42%), Positives = 39/70 (55%), Gaps = 5/70 (7%)
Frame = +1
Query: 298 WFHGKISRESAEKLLK-EEGEDGVFLVRESNTSPGDYVLSV-LHQGQ---VVHYQIRRHG 462
WF ISR +AE+LL + G FL+RES + PG Y LSV H GQ V+HY+I +
Sbjct: 29 WFFEGISRRNAEQLLMLPQNYSGCFLIRESQSFPGLYSLSVRQHSGQMHTVLHYKIYQLH 88
Query: 463 EDAFFSIEEH 492
F+ H
Sbjct: 89 NGWFYIQPNH 98
>UniRef50_UPI0000E218D0 Cluster: PREDICTED: similar to SH2B adaptor
protein 2, partial; n=1; Pan troglodytes|Rep: PREDICTED:
similar to SH2B adaptor protein 2, partial - Pan
troglodytes
Length = 178
Score = 46.4 bits (105), Expect = 9e-04
Identities = 21/47 (44%), Positives = 31/47 (65%), Gaps = 2/47 (4%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEG--EDGVFLVRESNTSPGDYVLSVLHQGQ 432
WFHG +SR A +L+ G G+F++R+S T PG+YVL+ QG+
Sbjct: 130 WFHGTLSRVKAAQLVLAGGPRNHGLFVIRQSETRPGEYVLTFNFQGK 176
>UniRef50_UPI0000D5645D Cluster: PREDICTED: similar to CG17367-PB,
isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG17367-PB, isoform B - Tribolium castaneum
Length = 488
Score = 46.4 bits (105), Expect = 9e-04
Identities = 21/53 (39%), Positives = 32/53 (60%), Gaps = 2/53 (3%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGE--DGVFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
WFHG + R A L+ +G G+FLVR+S T G++VL+ QG+ H ++
Sbjct: 322 WFHGTLGRSEATNLVLHDGARGHGLFLVRQSETRTGEFVLTFNFQGRAKHLRM 374
>UniRef50_UPI0000D55B96 Cluster: PREDICTED: similar to
Tyrosine-protein kinase Src64B (Dsrc64) isoform 2; n=1;
Tribolium castaneum|Rep: PREDICTED: similar to
Tyrosine-protein kinase Src64B (Dsrc64) isoform 2 -
Tribolium castaneum
Length = 473
Score = 46.4 bits (105), Expect = 9e-04
Identities = 23/59 (38%), Positives = 34/59 (57%), Gaps = 1/59 (1%)
Frame = +1
Query: 286 DNVNWFHGKISRESAEKLL-KEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRH 459
++ +WF +SR+ AEKLL EE G FLVR S +P Y LSV ++ Y ++ +
Sbjct: 131 ESEDWFFENVSRKEAEKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEEIREYHVKHY 189
>UniRef50_UPI0000D554A0 Cluster: PREDICTED: similar to CG11146-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG11146-PA - Tribolium castaneum
Length = 871
Score = 46.4 bits (105), Expect = 9e-04
Identities = 24/57 (42%), Positives = 34/57 (59%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGED 468
WFHG I+R AE +L+ E G FLVR S ++ DY LS+ +H +I++ G D
Sbjct: 770 WFHGAITRVEAENVLRMLRE-GSFLVRNSESTKQDYSLSLKSARGFMHMRIQKDGND 825
>UniRef50_A2BDR6 Cluster: SH2 domain containing 3C; n=5; Danio
rerio|Rep: SH2 domain containing 3C - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 635
Score = 46.4 bits (105), Expect = 9e-04
Identities = 21/53 (39%), Positives = 36/53 (67%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
W+HG+I E +E L+++EG+ FL+R+S +S GDYVL+ + +H+ I +
Sbjct: 50 WYHGRIPWEVSESLVQQEGD---FLIRDSLSSIGDYVLTCRWNQKALHFLITK 99
>UniRef50_Q9VMJ4 Cluster: CG9098-PA, isoform A; n=5; Diptera|Rep:
CG9098-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 944
Score = 46.4 bits (105), Expect = 9e-04
Identities = 19/53 (35%), Positives = 35/53 (66%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
W+HG + R+ AE++++ EG+ FLVR+ + P +YVLS + V+H+ + +
Sbjct: 240 WYHGALPRQRAEEIVQREGD---FLVRDCASQPDNYVLSCRSKAAVLHFVLNK 289
>UniRef50_Q9NH62 Cluster: Tyrosine kinase 5; n=2; Schistosoma
mansoni|Rep: Tyrosine kinase 5 - Schistosoma mansoni
(Blood fluke)
Length = 647
Score = 46.4 bits (105), Expect = 9e-04
Identities = 25/55 (45%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
Frame = +1
Query: 256 NSFLLRMNREDNVNWFHGKISRESAEKLLKEEGE-DGVFLVRESNTSPGDYVLSV 417
+SF+ + + WF +SR+ +E+LL EG GVFLVRES TS G LSV
Sbjct: 165 SSFVAKKGSVEAEEWFMPMLSRKDSERLLLLEGNAQGVFLVRESETSQGSLTLSV 219
>UniRef50_Q965N4 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 427
Score = 46.4 bits (105), Expect = 9e-04
Identities = 24/55 (43%), Positives = 34/55 (61%)
Frame = +1
Query: 301 FHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGE 465
FHG I R AEK+L E GE G +LVRESN S L ++ +V++Y++ G+
Sbjct: 51 FHGLIDRNEAEKMLLEAGE-GSYLVRESNRSRDACTLCMIFDAKVMNYKLYYDGQ 104
>UniRef50_Q06187 Cluster: Tyrosine-protein kinase BTK; n=54;
Gnathostomata|Rep: Tyrosine-protein kinase BTK - Homo
sapiens (Human)
Length = 659
Score = 46.4 bits (105), Expect = 9e-04
Identities = 24/71 (33%), Positives = 42/71 (59%), Gaps = 6/71 (8%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVL------HQGQVVHYQIRRH 459
W+ ++R AE+LLK+EG++G F+VR+S+ + G Y +SV QG + HY +
Sbjct: 281 WYSKHMTRSQAEQLLKQEGKEGGFIVRDSSKA-GKYTVSVFAKSTGDPQGVIRHYVVCST 339
Query: 460 GEDAFFSIEEH 492
+ ++ E+H
Sbjct: 340 PQSQYYLAEKH 350
>UniRef50_UPI0000E49A1C Cluster: PREDICTED: similar to Growth factor
receptor-bound protein 2; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Growth factor
receptor-bound protein 2 - Strongylocentrotus purpuratus
Length = 176
Score = 46.0 bits (104), Expect = 0.001
Identities = 24/51 (47%), Positives = 33/51 (64%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
WF I+R++AE LL +E +G FLVR S +S G Y LSV + V H++I
Sbjct: 14 WFFPTITRKNAELLLMQE-RNGAFLVRRSESSEGLYSLSVKYNESVQHFRI 63
>UniRef50_Q66I04 Cluster: Zgc:92124; n=1; Danio rerio|Rep: Zgc:92124
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 510
Score = 46.0 bits (104), Expect = 0.001
Identities = 27/72 (37%), Positives = 42/72 (58%), Gaps = 6/72 (8%)
Frame = +1
Query: 256 NSFLLRMNREDNVNWFHGKISRESAEK-LLKEEGEDGVFLVRESNTSPGDYVLSVLH--- 423
++++ + + WF+ I+R+ AE+ LL + G +L+RES TS G Y LS+
Sbjct: 113 SNYVAEADTMETEEWFYKDITRKDAERQLLAPANKPGSYLIRESETSKGSYSLSIRDVDA 172
Query: 424 QGQ--VVHYQIR 453
QGQ V HY+IR
Sbjct: 173 QGQDVVKHYKIR 184
>UniRef50_Q4RNX3 Cluster: Chromosome 10 SCAF15009, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 10 SCAF15009, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 466
Score = 46.0 bits (104), Expect = 0.001
Identities = 29/75 (38%), Positives = 38/75 (50%), Gaps = 5/75 (6%)
Frame = +1
Query: 268 LRMNREDNVNWFHGKISRESAEKLLKEEGE-DGVFLVRESNTSPGDYVLSVL---HQGQ- 432
+ M+ + WF ISR A + L G G FLVRES T+PG Y LS+ + G
Sbjct: 106 IAMSTMETEAWFFKNISRNEATRRLMAPGNTQGSFLVRESETTPGSYSLSMRDFDNNGDG 165
Query: 433 VVHYQIRRHGEDAFF 477
V HY+IR F+
Sbjct: 166 VKHYRIRNMDNGGFY 180
>UniRef50_Q9H3Y6 Cluster: Tyrosine-protein kinase Srms; n=17;
Amniota|Rep: Tyrosine-protein kinase Srms - Homo sapiens
(Human)
Length = 488
Score = 46.0 bits (104), Expect = 0.001
Identities = 22/61 (36%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
Frame = +1
Query: 298 WFHGKISRESAEKLL-KEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAF 474
W+ +SR A++LL E G FL+R S +S G Y LSV Q +V HY++ + +
Sbjct: 120 WYFSGVSRTQAQQLLLSPPNEPGAFLIRPSESSLGGYSLSVRAQAKVCHYRVSMAADGSL 179
Query: 475 F 477
+
Sbjct: 180 Y 180
>UniRef50_O14796 Cluster: SH2 domain-containing protein 1B; n=19;
Theria|Rep: SH2 domain-containing protein 1B - Homo
sapiens (Human)
Length = 132
Score = 46.0 bits (104), Expect = 0.001
Identities = 22/57 (38%), Positives = 36/57 (63%), Gaps = 2/57 (3%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQI--RRHG 462
++HG+++++ E LL +EG DG FL+R+S + PG L V + V Y+I +HG
Sbjct: 5 YYHGRLTKQDCETLLLKEGVDGNFLLRDSESIPGVLCLCVSFKNIVYTYRIFREKHG 61
>UniRef50_UPI00015B58E2 Cluster: PREDICTED: similar to signal
transduction protein lnk-realted; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to signal
transduction protein lnk-realted - Nasonia vitripennis
Length = 458
Score = 45.6 bits (103), Expect = 0.002
Identities = 21/53 (39%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDG--VFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
WFHG + R A +L+ +G FLVR+S T G+YVL+ QG+ H ++
Sbjct: 270 WFHGTLPRSDAAQLVLHNATEGHGTFLVRQSETRKGEYVLTFNFQGRAKHLRM 322
>UniRef50_Q4T2Z8 Cluster: Chromosome 18 SCAF10147, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 18 SCAF10147, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 279
Score = 45.6 bits (103), Expect = 0.002
Identities = 21/40 (52%), Positives = 31/40 (77%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSV 417
WF G++SR AEK L+ + + GVFLVRES ++PG++ +SV
Sbjct: 60 WFVGRVSRLEAEKRLRWQ-DPGVFLVRESESAPGEFSVSV 98
>UniRef50_Q4SBL7 Cluster: Chromosome 15 SCAF14667, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 15
SCAF14667, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 723
Score = 45.6 bits (103), Expect = 0.002
Identities = 22/52 (42%), Positives = 28/52 (53%)
Frame = +1
Query: 286 DNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVH 441
D W+ G I R AE++L+ DG FL+RES T G Y SV+ G H
Sbjct: 618 DESTWYVGDIKRSQAEEMLRGTC-DGTFLIRESQTQKGSYACSVVVDGDTKH 668
Score = 35.9 bits (79), Expect = 1.3
Identities = 17/49 (34%), Positives = 31/49 (63%), Gaps = 1/49 (2%)
Frame = +1
Query: 286 DNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTS-PGDYVLSVLHQG 429
++ W+ G+ISRE + L++ DG FLVR++++ G+Y L++ G
Sbjct: 358 NDAEWYWGEISREEVNEKLRDT-PDGTFLVRDASSKLEGEYTLTLRKGG 405
>UniRef50_Q9Y1Y4 Cluster: Tyrosine-protein kinase; n=1; Ephydatia
fluviatilis|Rep: Tyrosine-protein kinase - Ephydatia
fluviatilis
Length = 853
Score = 45.6 bits (103), Expect = 0.002
Identities = 24/61 (39%), Positives = 35/61 (57%), Gaps = 1/61 (1%)
Frame = +1
Query: 277 NREDNVNWFHGKISRESAEKLLKEEG-EDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIR 453
N E H IS +S EK+L+ EDG FL+RES +S Y LS+ H ++ +++I
Sbjct: 353 NDECKAELCHVAISPDSVEKVLEMYNKEDGTFLIRESRSSENSYTLSLCHNQRIKNFRIS 412
Query: 454 R 456
R
Sbjct: 413 R 413
>UniRef50_Q7Z7G1 Cluster: MIST; n=18; Eutheria|Rep: MIST - Homo
sapiens (Human)
Length = 428
Score = 45.6 bits (103), Expect = 0.002
Identities = 24/68 (35%), Positives = 43/68 (63%), Gaps = 4/68 (5%)
Frame = +1
Query: 262 FLLRMNRED--NVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGD--YVLSVLHQG 429
F R +R+D + W+ G+ SR++ E+ +E +DG FLVR+ +T + YVL+V ++
Sbjct: 295 FPKRSDRKDVQHNEWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYEN 354
Query: 430 QVVHYQIR 453
+V + +IR
Sbjct: 355 KVYNVKIR 362
>UniRef50_Q96JZ2 Cluster: Hematopoietic SH2 domain-containing
protein; n=72; Eumetazoa|Rep: Hematopoietic SH2
domain-containing protein - Homo sapiens (Human)
Length = 352
Score = 45.6 bits (103), Expect = 0.002
Identities = 30/75 (40%), Positives = 38/75 (50%), Gaps = 1/75 (1%)
Frame = +1
Query: 283 EDNV-NWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRH 459
+D V WFHG ISRE AE LL E G FL+R S++ G Y LS Q H+ ++
Sbjct: 28 QDGVPEWFHGAISREDAENLL-ESQPLGSFLIRVSHSHVG-YTLSYKAQSSCCHFMVKLL 85
Query: 460 GEDAFFSIEEHTTVH 504
+D F I H
Sbjct: 86 -DDGTFMIPGEKVAH 99
>UniRef50_UPI0000E47C6E Cluster: PREDICTED: similar to Grb2 adaptor
protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to Grb2 adaptor protein -
Strongylocentrotus purpuratus
Length = 532
Score = 45.2 bits (102), Expect = 0.002
Identities = 23/58 (39%), Positives = 32/58 (55%), Gaps = 4/58 (6%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVL----HQGQVVHYQIRRH 459
WF GKISR AE++L G L+RES PG Y LSV ++ + HY +++
Sbjct: 206 WFFGKISRAKAEEILHLSTSHGDLLLRESEAHPGQYTLSVRQDTDNKSLIRHYMFKKN 263
>UniRef50_O60880-5 Cluster: Isoform E of O60880 ; n=5; Eutheria|Rep:
Isoform E of O60880 - Homo sapiens (Human)
Length = 76
Score = 45.2 bits (102), Expect = 0.002
Identities = 21/38 (55%), Positives = 27/38 (71%)
Frame = +1
Query: 286 DNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPG 399
D V +HGKISRE+ EKLL G DG +L+R+S + PG
Sbjct: 2 DAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPG 39
>UniRef50_Q60I21 Cluster: TEC family protein tyrosine kinase; n=1;
Eptatretus burgeri|Rep: TEC family protein tyrosine
kinase - Eptatretus burgeri (Inshore hagfish)
Length = 636
Score = 45.2 bits (102), Expect = 0.002
Identities = 29/80 (36%), Positives = 44/80 (55%), Gaps = 3/80 (3%)
Frame = +1
Query: 265 LLRMNREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSV---LHQGQV 435
L R + E N WF I+R AE+LL++ G +G FLVRES + G +SV + V
Sbjct: 251 LTRFDLEQN-RWFCKDITRAKAEQLLRQAGSEGSFLVRES-SQVGKLTVSVYSCIPCEVV 308
Query: 436 VHYQIRRHGEDAFFSIEEHT 495
HY +++ ++ E+HT
Sbjct: 309 KHYHVKQLPTGEWYLAEKHT 328
>UniRef50_Q70DV1 Cluster: Src tyrosine kinase; n=1; Schistosoma
mansoni|Rep: Src tyrosine kinase - Schistosoma mansoni
(Blood fluke)
Length = 647
Score = 45.2 bits (102), Expect = 0.002
Identities = 23/53 (43%), Positives = 31/53 (58%), Gaps = 1/53 (1%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGED-GVFLVRESNTSPGDYVLSVLHQGQVVHYQIR 453
W+ G++ R AE L+ G D G FLVR S + +Y LSV + V HY+IR
Sbjct: 222 WYFGELKRIEAEHYLQLPGNDHGSFLVRISESQSSEYSLSVREENTVKHYRIR 274
>UniRef50_P08631 Cluster: Tyrosine-protein kinase HCK; n=32;
Euteleostomi|Rep: Tyrosine-protein kinase HCK - Homo
sapiens (Human)
Length = 526
Score = 45.2 bits (102), Expect = 0.002
Identities = 28/80 (35%), Positives = 43/80 (53%), Gaps = 6/80 (7%)
Frame = +1
Query: 256 NSFLLRMNREDNVNWFHGKISRESAEKLLKEEGED-GVFLVRESNTSPGDYVLSVL---- 420
++++ R++ + WF ISR+ AE+ L G G F++R+S T+ G Y LSV
Sbjct: 130 SNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDP 189
Query: 421 HQGQVV-HYQIRRHGEDAFF 477
QG V HY+IR F+
Sbjct: 190 RQGDTVKHYKIRTLDNGGFY 209
>UniRef50_Q4SKC0 Cluster: Chromosome 13 SCAF14566, whole genome
shotgun sequence; n=2; Euteleostei|Rep: Chromosome 13
SCAF14566, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1249
Score = 44.8 bits (101), Expect = 0.003
Identities = 19/58 (32%), Positives = 30/58 (51%)
Frame = +1
Query: 289 NVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHG 462
N WF+ +SR AE L DG FL+R+ P + ++ G+V H +I++ G
Sbjct: 629 NEGWFYSDLSRGQAEDYLMRIPRDGAFLIRQREGEPDSFAITFKGDGKVKHCRIQKEG 686
Score = 42.3 bits (95), Expect = 0.015
Identities = 25/59 (42%), Positives = 33/59 (55%), Gaps = 7/59 (11%)
Frame = +1
Query: 298 WFHG--KISRESAEKLLKEE-----GEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIR 453
WFHG K R+ AE+L+ E G+DG FLVR S+ Y LS G+V H ++R
Sbjct: 517 WFHGHMKDGRQMAERLIYEYCAETGGQDGTFLVRPSDRVVLSYTLSFWRNGRVQHCRVR 575
>UniRef50_Q7K137 Cluster: LD10453p; n=4; Diptera|Rep: LD10453p -
Drosophila melanogaster (Fruit fly)
Length = 723
Score = 44.4 bits (100), Expect = 0.004
Identities = 25/79 (31%), Positives = 44/79 (55%), Gaps = 3/79 (3%)
Frame = +1
Query: 223 NNHDVIHIT*ENSFLLRMNREDNV-NWFHGKISRESAEKLL--KEEGEDGVFLVRESNTS 393
+N D I T ++ + + E +V WFHG ++R A +++ + G FLVR+S T
Sbjct: 416 SNFDGIEGTENDADVADLTAEMSVFPWFHGTLTRSEAARMVLHSDAAGHGYFLVRQSETR 475
Query: 394 PGDYVLSVLHQGQVVHYQI 450
G++VL+ QG+ H ++
Sbjct: 476 RGEFVLTFNFQGRAKHLRL 494
>UniRef50_A7RZ47 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 948
Score = 44.4 bits (100), Expect = 0.004
Identities = 24/54 (44%), Positives = 33/54 (61%), Gaps = 1/54 (1%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQ-VVHYQIRR 456
WFHGKI+ E AE L++ GE FLVRE PG Y ++V ++ Q +H I +
Sbjct: 58 WFHGKITAEYAEMLMRGAGE---FLVREDPAMPGMYFIAVRNKEQETLHLAITK 108
>UniRef50_UPI00015B5EF2 Cluster: PREDICTED: similar to
ENSANGP00000021630; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000021630 - Nasonia
vitripennis
Length = 389
Score = 44.0 bits (99), Expect = 0.005
Identities = 35/100 (35%), Positives = 48/100 (48%), Gaps = 7/100 (7%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSV-----LHQGQVVHYQIRR-- 456
WF I RE ++L +E E G F+VRES + PG Y LS+ + HY I R
Sbjct: 256 WFQAGIPREITLEVLSQEPE-GAFMVRESTSKPGCYALSLRVPREFQPSGIAHYLIMRTN 314
Query: 457 HGEDAFFSIEEHTTVHGWILLYNITVVIQMDLLLGCPLSV 576
G +E TT+ I +++ M LL CPLS+
Sbjct: 315 KGYKIKGFTKEFTTLTALITHHSV-----MPELLPCPLSL 349
>UniRef50_A2AQ87 Cluster: Novel protein (Possible orthologue of
human Src homology 2 domain containing F (SHF)); n=10;
Euteleostomi|Rep: Novel protein (Possible orthologue of
human Src homology 2 domain containing F (SHF)) - Mus
musculus (Mouse)
Length = 446
Score = 43.6 bits (98), Expect = 0.006
Identities = 23/63 (36%), Positives = 35/63 (55%)
Frame = +1
Query: 286 DNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGE 465
+N W+HG ISR AE LL+ ++ +LVR S TS D+ LS+ +H ++ R E
Sbjct: 342 ENQVWYHGAISRTDAENLLR-LCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKLSRTKE 400
Query: 466 DAF 474
+
Sbjct: 401 HKY 403
>UniRef50_Q13239 Cluster: SRC-like-adapter; n=26; Euteleostomi|Rep:
SRC-like-adapter - Homo sapiens (Human)
Length = 276
Score = 43.6 bits (98), Expect = 0.006
Identities = 24/54 (44%), Positives = 34/54 (62%), Gaps = 1/54 (1%)
Frame = +1
Query: 298 WFHGKISRESAEKLLK-EEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
W + R+ AE+LL+ + + G F++RES T G Y LSV H+ QV HY+I R
Sbjct: 84 WLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRHR-QVKHYRIFR 136
>UniRef50_UPI0000E4816C Cluster: PREDICTED: similar to
phosphoinositide-3-kinase; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to
phosphoinositide-3-kinase - Strongylocentrotus
purpuratus
Length = 820
Score = 43.2 bits (97), Expect = 0.008
Identities = 19/44 (43%), Positives = 28/44 (63%)
Frame = +1
Query: 286 DNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSV 417
++ W+ G ISRE + LK+ DG FLVR+S PG+Y L++
Sbjct: 498 NDAEWYWGSISREEVNEKLKDM-PDGTFLVRDSKQEPGNYTLTL 540
>UniRef50_Q85476 Cluster: (recovered insertion mutant of B77) src;
n=4; root|Rep: (recovered insertion mutant of B77) src -
Rous sarcoma virus
Length = 285
Score = 43.2 bits (97), Expect = 0.008
Identities = 21/41 (51%), Positives = 27/41 (65%), Gaps = 1/41 (2%)
Frame = +1
Query: 298 WFHGKISRESAEKLL-KEEGEDGVFLVRESNTSPGDYVLSV 417
W+ GKI+R +E+LL E G FLVR+S T+ G Y LSV
Sbjct: 229 WYFGKITRRESERLLLNPENPRGTFLVRKSETTKGAYCLSV 269
>UniRef50_Q4SII9 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 5
SCAF14581, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 921
Score = 42.7 bits (96), Expect = 0.011
Identities = 22/52 (42%), Positives = 32/52 (61%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIR 453
W+HG I R ++LL ++G+ FLVR+S PG YVLSV G H+ ++
Sbjct: 528 WYHGAIPRLEVQQLLTKDGD---FLVRKSQEKPG-YVLSVHWSGACKHFLVQ 575
>UniRef50_Q7M4L6 Cluster: Shb-like adapter protein, Shf; n=21;
Amniota|Rep: Shb-like adapter protein, Shf - Homo
sapiens (Human)
Length = 480
Score = 42.7 bits (96), Expect = 0.011
Identities = 22/57 (38%), Positives = 33/57 (57%)
Frame = +1
Query: 286 DNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
+N W+HG ISR AE LL+ ++ +LVR S TS D+ LS+ +H ++ R
Sbjct: 376 ENQVWYHGAISRTDAENLLR-LCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKLSR 431
>UniRef50_P51451 Cluster: Tyrosine-protein kinase BLK; n=5;
Euteleostomi|Rep: Tyrosine-protein kinase BLK - Homo
sapiens (Human)
Length = 505
Score = 42.7 bits (96), Expect = 0.011
Identities = 27/79 (34%), Positives = 44/79 (55%), Gaps = 5/79 (6%)
Frame = +1
Query: 256 NSFLLRMNREDNVNWFHGKISRESAEK-LLKEEGEDGVFLVRESNTSPGDYVLS---VLH 423
++F+ R+ + WF R+ AE+ LL + G FL+RES T+ G + LS V
Sbjct: 110 SNFVARVESLEMERWFFRSQGRKEAERQLLAPINKAGSFLIRESETNKGAFSLSVKDVTT 169
Query: 424 QGQVV-HYQIRRHGEDAFF 477
QG+++ HY+IR E ++
Sbjct: 170 QGELIKHYKIRCLDEGGYY 188
>UniRef50_UPI0000F2148D Cluster: PREDICTED: similar to signal
transduction regulatory protein SAP-1; n=1; Danio
rerio|Rep: PREDICTED: similar to signal transduction
regulatory protein SAP-1 - Danio rerio
Length = 143
Score = 42.3 bits (95), Expect = 0.015
Identities = 20/58 (34%), Positives = 32/58 (55%)
Frame = +1
Query: 301 FHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAF 474
+HG I+++ E+LL +G DG +L+R+S T G L V V Y+I + +F
Sbjct: 6 YHGAITKQRCEELLGNKGRDGTYLIRDSETIQGAMCLCVYKHKVVYTYRILQTHSGSF 63
>UniRef50_UPI0000F1EB7D Cluster: PREDICTED: hypothetical protein;
n=3; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 510
Score = 42.3 bits (95), Expect = 0.015
Identities = 28/84 (33%), Positives = 40/84 (47%), Gaps = 4/84 (4%)
Frame = +1
Query: 256 NSFLLRMNREDNVNWFHGKISRESAE-KLLKEEGEDGVFLVRESNTSPGDYVLSVL---H 423
N FL R W+ G ++R E LL E + G FLVR S YVLSVL
Sbjct: 109 NHFLARRQTVKEQPWYFGTLNRFETEILLLAPENDVGAFLVRHSEKDNIGYVLSVLSGDR 168
Query: 424 QGQVVHYQIRRHGEDAFFSIEEHT 495
+V H +I ++ ++F+ + T
Sbjct: 169 SREVKHIKIHQNQNESFYLDKSQT 192
>UniRef50_Q9BI25 Cluster: SHK1 protein; n=2; Dictyostelium
discoideum|Rep: SHK1 protein - Dictyostelium discoideum
(Slime mold)
Length = 527
Score = 42.3 bits (95), Expect = 0.015
Identities = 23/54 (42%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLS-VLHQGQVVHYQIRR 456
WFHG IS +E L+++ E G FLVR S + G Y +S V G + H +I R
Sbjct: 424 WFHGDISTSESENRLRQKPE-GTFLVRFSTSEYGAYTISKVSKNGGISHQRIHR 476
>UniRef50_Q5BW49 Cluster: SJCHGC04880 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC04880 protein - Schistosoma
japonicum (Blood fluke)
Length = 243
Score = 42.3 bits (95), Expect = 0.015
Identities = 26/77 (33%), Positives = 44/77 (57%), Gaps = 8/77 (10%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHY------QIR-- 453
W+ G+ISRE A ++L ++ G FL+R+S T G YVL++ +V Y Q++
Sbjct: 9 WYFGEISREKANEILIDQ-PVGTFLIRDSTTKSG-YVLAIKEANEVKRYLLTWSPQLKKF 66
Query: 454 RHGEDAFFSIEEHTTVH 504
+ GE + S++E +H
Sbjct: 67 KFGETLYSSLDELVRLH 83
>UniRef50_UPI0000E48AB6 Cluster: PREDICTED: similar to B-cell
linker; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to B-cell linker - Strongylocentrotus
purpuratus
Length = 591
Score = 41.9 bits (94), Expect = 0.019
Identities = 22/70 (31%), Positives = 40/70 (57%), Gaps = 2/70 (2%)
Frame = +1
Query: 271 RMNREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNT-SPGD-YVLSVLHQGQVVHY 444
++N + W++G I R+ +EK L + +DG F+VR S P + Y L++ G+V +
Sbjct: 477 QVNELEGHPWYNGGIGRQESEKYLHQCRKDGAFIVRNSTRGDPANPYSLALWFNGRVRNL 536
Query: 445 QIRRHGEDAF 474
QIR+ + +
Sbjct: 537 QIRKRKDQRY 546
>UniRef50_Q3ZB94 Cluster: Zgc:113360; n=3; Clupeocephala|Rep:
Zgc:113360 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 271
Score = 41.9 bits (94), Expect = 0.019
Identities = 25/54 (46%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGED-GVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
W +SR+ AE+LL G G FL+RES G Y LSV H+ V HY+I R
Sbjct: 84 WLFEGVSRQKAEELLSLPGNSAGSFLIRESPRERGLYSLSVRHR-SVKHYKIFR 136
>UniRef50_Q9V3C8 Cluster: CG3715-PA; n=7; Endopterygota|Rep:
CG3715-PA - Drosophila melanogaster (Fruit fly)
Length = 409
Score = 41.9 bits (94), Expect = 0.019
Identities = 21/41 (51%), Positives = 28/41 (68%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVL 420
WFH ISR +E+LL+++G+ FLVRES G YVL+ L
Sbjct: 301 WFHAGISRPISERLLQQDGD---FLVRESQGKRGQYVLTGL 338
>UniRef50_Q6VYH9 Cluster: Hematopoietic SH2 domain-containing
protein; n=2; Murinae|Rep: Hematopoietic SH2
domain-containing protein - Mus musculus (Mouse)
Length = 334
Score = 41.9 bits (94), Expect = 0.019
Identities = 25/67 (37%), Positives = 35/67 (52%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAFF 477
WFHG ISRE+AE +L E G FL+R S++ G Y LS Q H+ ++ +
Sbjct: 34 WFHGTISREAAENML-ESQPLGTFLIRVSHSHVG-YTLSYKAQTCCRHFMVKLSEDGTCA 91
Query: 478 SIEEHTT 498
+H T
Sbjct: 92 FAGDHMT 98
>UniRef50_UPI0000D9EE2E Cluster: PREDICTED: similar to src homology
2 domain-containing transforming protein D; n=1; Macaca
mulatta|Rep: PREDICTED: similar to src homology 2
domain-containing transforming protein D - Macaca
mulatta
Length = 221
Score = 41.5 bits (93), Expect = 0.025
Identities = 23/57 (40%), Positives = 32/57 (56%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGED 468
WFHG ++R AE LL ++G +LVR S TSP D LS+ +H + R E+
Sbjct: 121 WFHGPLNRADAESLLSL-CKEGSYLVRLSETSPQDCSLSLRSSQGFLHLKFARTREN 176
>UniRef50_UPI00005A0859 Cluster: PREDICTED: similar to SH2 domain
containing 4B; n=1; Canis lupus familiaris|Rep:
PREDICTED: similar to SH2 domain containing 4B - Canis
familiaris
Length = 488
Score = 41.5 bits (93), Expect = 0.025
Identities = 27/63 (42%), Positives = 32/63 (50%)
Frame = +1
Query: 277 NREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
N + WFHG ISRE AE LL E +G FLVR S G Y LS Q H+ +
Sbjct: 375 NTKSIAPWFHGIISREDAEDLL-ENMTEGAFLVRVSEKIWG-YTLSYRLQKGFKHFLVDA 432
Query: 457 HGE 465
G+
Sbjct: 433 SGD 435
>UniRef50_Q4RPN2 Cluster: Chromosome 12 SCAF15007, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 12 SCAF15007, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 868
Score = 41.5 bits (93), Expect = 0.025
Identities = 19/53 (35%), Positives = 34/53 (64%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
W+HG I E +E L+ G+ FL+R+S ++ G++VL+ Q + +H+ IR+
Sbjct: 280 WYHGPIPWEVSESLVVNHGD---FLIRDSQSNRGNFVLTSNWQQKTLHFLIRK 329
>UniRef50_Q1ED32 Cluster: Zgc:136231; n=1; Danio rerio|Rep:
Zgc:136231 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 222
Score = 41.5 bits (93), Expect = 0.025
Identities = 26/58 (44%), Positives = 34/58 (58%), Gaps = 6/58 (10%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEG-EDGVFLVRESNTSPGDYVLSVL----HQGQVV-HYQIR 453
WF ++R E+LL G + G FLVRES T+ G + LS+ QG VV HY+IR
Sbjct: 104 WFFKDMNRRDTERLLLAPGNKPGSFLVRESETTKGAFSLSIRDSTPEQGDVVKHYKIR 161
>UniRef50_A7SJB4 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 681
Score = 41.5 bits (93), Expect = 0.025
Identities = 18/39 (46%), Positives = 26/39 (66%)
Frame = +1
Query: 349 EGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGE 465
+G G F++R S+ SPGDY LS+ +Q V + IRR G+
Sbjct: 3 DGAVGSFMIRPSDKSPGDYSLSLRYQDGVTRFLIRRQGQ 41
>UniRef50_UPI000155BA92 Cluster: PREDICTED: similar to Fyn-related
kinase, partial; n=1; Ornithorhynchus anatinus|Rep:
PREDICTED: similar to Fyn-related kinase, partial -
Ornithorhynchus anatinus
Length = 186
Score = 41.1 bits (92), Expect = 0.034
Identities = 21/40 (52%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGE-DGVFLVRESNTSPGDYVLS 414
WF G I R AEK L G G FL+RES + GDY LS
Sbjct: 147 WFFGAIKRVDAEKQLLYSGNRPGAFLIRESESQKGDYSLS 186
>UniRef50_UPI00006A0536 Cluster: Nck1-prov protein.; n=1; Xenopus
tropicalis|Rep: Nck1-prov protein. - Xenopus tropicalis
Length = 345
Score = 41.1 bits (92), Expect = 0.034
Identities = 15/32 (46%), Positives = 23/32 (71%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTS 393
W++GK++R AE L E G +G FL+R+S +S
Sbjct: 282 WYYGKVTRHQAEMALNERGNEGDFLIRDSESS 313
>UniRef50_Q08BY6 Cluster: Zgc:153964; n=3; Danio rerio|Rep:
Zgc:153964 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 511
Score = 41.1 bits (92), Expect = 0.034
Identities = 22/60 (36%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Frame = +1
Query: 298 WFHGKISRESA-EKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAF 474
WF GK++R A L+ +E G FLVR S + YVLSV + H++I + G+ +
Sbjct: 134 WFFGKMNRVGAVSHLMSDENNYGSFLVRVSESDDMGYVLSVRTKENAKHFKIFQTGDQFY 193
>UniRef50_Q17PR7 Cluster: Putative uncharacterized protein; n=1;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 312
Score = 41.1 bits (92), Expect = 0.034
Identities = 20/61 (32%), Positives = 35/61 (57%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAFF 477
W+ GK++R +A+K L + ++G FLVR+S T + +S G +H +I ++ F
Sbjct: 162 WYWGKLTRSAAQKRLARQ-DNGTFLVRDSETEKHQFAISFRSSGITLHCRIDYKDKNWSF 220
Query: 478 S 480
S
Sbjct: 221 S 221
>UniRef50_A7RK55 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 250
Score = 41.1 bits (92), Expect = 0.034
Identities = 16/46 (34%), Positives = 30/46 (65%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQV 435
W+ G+ S+E+ +++ EDG F+VR+S PG+Y L+++ G +
Sbjct: 6 WYWGEASKEAVNARMRDT-EDGTFIVRDSKRFPGEYTLTLMKGGVI 50
>UniRef50_Q5SQS7 Cluster: Novel SH2 domain-containing protein; n=28;
Euteleostomi|Rep: Novel SH2 domain-containing protein -
Homo sapiens (Human)
Length = 431
Score = 41.1 bits (92), Expect = 0.034
Identities = 26/56 (46%), Positives = 30/56 (53%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGE 465
WFHG ISRE AE LL E +G FLVR S G Y LS Q H+ + G+
Sbjct: 325 WFHGIISREDAEALL-ENMTEGAFLVRVSEKIWG-YTLSYRLQKGFKHFLVDASGD 378
>UniRef50_O00459 Cluster: Phosphatidylinositol 3-kinase regulatory
subunit beta; n=114; Euteleostomi|Rep:
Phosphatidylinositol 3-kinase regulatory subunit beta -
Homo sapiens (Human)
Length = 728
Score = 41.1 bits (92), Expect = 0.034
Identities = 23/53 (43%), Positives = 31/53 (58%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRR 456
W+ GKI+R AE++L + DG FL+RES + G Y SV+ G H I R
Sbjct: 622 WYVGKINRTQAEEMLSGK-RDGTFLIRES-SQRGCYACSVVVDGDTKHCVIYR 672
Score = 34.7 bits (76), Expect = 2.9
Identities = 17/48 (35%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
Frame = +1
Query: 289 NVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTS-PGDYVLSVLHQG 429
+ W+ G ISRE + L++ DG FLVR++++ G+Y L++ G
Sbjct: 327 DAEWYWGDISREEVNEKLRDT-PDGTFLVRDASSKIQGEYTLTLRKGG 373
>UniRef50_Q8T6F8 Cluster: SRC-1; n=3; Caenorhabditis|Rep: SRC-1 -
Caenorhabditis elegans
Length = 533
Score = 40.7 bits (91), Expect = 0.045
Identities = 25/87 (28%), Positives = 41/87 (47%), Gaps = 7/87 (8%)
Frame = +1
Query: 259 SFLLRMNREDNVNWFHGKISRESAEKL-LKEEGEDGVFLVRESNTSPGDYVLSV------ 417
+F+ + ++ W+ GKI R AE+L L G FL+RE ++ L++
Sbjct: 125 NFVAKQQTIESEEWYAGKIPRNRAERLVLSSHLPKGTFLIREREADTREFALTIRDTDDQ 184
Query: 418 LHQGQVVHYQIRRHGEDAFFSIEEHTT 498
+ G V HY+I+R D + I T
Sbjct: 185 RNGGTVKHYKIKRLDHDQGYFITTRRT 211
>UniRef50_Q7JVF1 Cluster: LP02169p; n=2; Sophophora|Rep: LP02169p -
Drosophila melanogaster (Fruit fly)
Length = 342
Score = 40.7 bits (91), Expect = 0.045
Identities = 23/67 (34%), Positives = 36/67 (53%)
Frame = +1
Query: 289 NVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGED 468
N W+ G+ISR +++ L ++ G FLVR+S TS + LS +HY++ D
Sbjct: 186 NQVWYWGEISRRDSQRQLSDK-PTGSFLVRDSETSGSQFTLSFRIVNVTLHYRLEY--RD 242
Query: 469 AFFSIEE 489
F+ EE
Sbjct: 243 NFWHFEE 249
>UniRef50_O18683 Cluster: P60 protein; n=2; Sophophora|Rep: P60
protein - Drosophila melanogaster (Fruit fly)
Length = 506
Score = 40.7 bits (91), Expect = 0.045
Identities = 18/44 (40%), Positives = 30/44 (68%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQG 429
W+ G+ISRE A+ +L + DG FLVR++ + G+Y L+++ G
Sbjct: 32 WYWGRISREEAKSILHGK-PDGSFLVRDALSMKGEYTLTLMKDG 74
>UniRef50_Q56A36 Cluster: Hematopoietic SH2 domain-containing
protein homolog; n=3; Danio rerio|Rep: Hematopoietic SH2
domain-containing protein homolog - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 365
Score = 40.7 bits (91), Expect = 0.045
Identities = 30/102 (29%), Positives = 51/102 (50%), Gaps = 5/102 (4%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAFF 477
WFHG ISR++AE++L + G FL+R S + G Y LS + + H+ I ++ F
Sbjct: 34 WFHGIISRKAAEEMLMCK-PAGYFLIRVSESRVG-YTLSYRAEDRCRHFMINVLPDNQFM 91
Query: 478 SIEEHT---TVHGWILLYNITVVIQMDLLL--GCPLSVKENH 588
+ E T ++H + + ++ + LL C K N+
Sbjct: 92 IVGEKTVYCSLHDLVAFHRRCPILPYNELLTVACEQGGKTNY 133
>UniRef50_UPI00015B496D Cluster: PREDICTED: similar to conserved
hypothetical protein; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to conserved hypothetical protein -
Nasonia vitripennis
Length = 1182
Score = 40.3 bits (90), Expect = 0.059
Identities = 21/56 (37%), Positives = 34/56 (60%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGE 465
W+HG I+R AE +L+ E G +LVR S ++ DY LS+ +H +I+++ E
Sbjct: 1081 WYHGSITRIEAEAVLRLLRE-GSYLVRNSESTKQDYSLSLKSARGFMHMRIQKNEE 1135
>UniRef50_UPI0000DB713D Cluster: PREDICTED: similar to CG11146-PA
isoform 2; n=1; Apis mellifera|Rep: PREDICTED: similar to
CG11146-PA isoform 2 - Apis mellifera
Length = 1122
Score = 40.3 bits (90), Expect = 0.059
Identities = 21/56 (37%), Positives = 34/56 (60%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGE 465
W+HG I+R AE +L+ E G +LVR S ++ DY LS+ +H +I+++ E
Sbjct: 1021 WYHGSITRIEAEAVLRLLRE-GSYLVRNSESTKQDYSLSLKSARGFMHMRIQKNEE 1075
>UniRef50_UPI0000D56E93 Cluster: PREDICTED: similar to SH2 domain
containing 4B; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to SH2 domain containing 4B - Tribolium
castaneum
Length = 412
Score = 40.3 bits (90), Expect = 0.059
Identities = 34/104 (32%), Positives = 51/104 (49%), Gaps = 4/104 (3%)
Frame = +1
Query: 274 MNREDNV-NWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQI 450
++R +NV +WFHG I+R AEKLL + G FLVR S G Y +S + + HY +
Sbjct: 300 LDRSNNVESWFHGLITRSEAEKLLLDR-PYGSFLVRLSERIWG-YAISYRAKEKCKHYLV 357
Query: 451 RRHGEDAFFSIE--EHTTVHGWILLYNITVVIQMDLLL-GCPLS 573
+ F EH T+ I + + + + L+ CP S
Sbjct: 358 SAGLKYQFLGNNQIEHETLRDLIEYHRVHPLTGGEKLVEACPRS 401
>UniRef50_UPI00015A58A4 Cluster: UPI00015A58A4 related cluster; n=1;
Danio rerio|Rep: UPI00015A58A4 UniRef100 entry - Danio
rerio
Length = 426
Score = 40.3 bits (90), Expect = 0.059
Identities = 21/58 (36%), Positives = 36/58 (62%), Gaps = 6/58 (10%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQ------GQVVHYQIR 453
WF ++R AE+LL++EG++G F+VR S+ + G Y +S+ + + HYQI+
Sbjct: 288 WFSKNVNRNKAEELLRKEGKEGGFMVRLSSNT-GTYTVSLYTKSTSDGAAAIRHYQIK 344
>UniRef50_Q7T0U4 Cluster: MGC68984 protein; n=2; Xenopus|Rep:
MGC68984 protein - Xenopus laevis (African clawed frog)
Length = 266
Score = 40.3 bits (90), Expect = 0.059
Identities = 23/66 (34%), Positives = 33/66 (50%), Gaps = 6/66 (9%)
Frame = +1
Query: 298 WFHGKISRESAEKLLK-EEGEDGVFLVRESNTSPGDYVLSV-----LHQGQVVHYQIRRH 459
W + I+RE AE+LL G FL+RES T G Y LS+ + + HY+I +
Sbjct: 89 WLYKGINREKAEELLMVNSNRSGSFLIRESETRSGSYTLSIRKTNHTSRDSIKHYRIHQL 148
Query: 460 GEDAFF 477
F+
Sbjct: 149 DNGWFY 154
>UniRef50_P42680 Cluster: Tyrosine-protein kinase Tec; n=86;
Coelomata|Rep: Tyrosine-protein kinase Tec - Homo
sapiens (Human)
Length = 631
Score = 40.3 bits (90), Expect = 0.059
Identities = 18/49 (36%), Positives = 31/49 (63%)
Frame = +1
Query: 271 RMNREDNVNWFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSV 417
+ N D W+ ++R AE+LL+ E ++G F+VR+S + PG Y +S+
Sbjct: 238 KSNNLDQYEWYCRNMNRSKAEQLLRSEDKEGGFMVRDS-SQPGLYTVSL 285
>UniRef50_P00528 Cluster: Tyrosine-protein kinase Src64B; n=6;
Endopterygota|Rep: Tyrosine-protein kinase Src64B -
Drosophila melanogaster (Fruit fly)
Length = 552
Score = 40.3 bits (90), Expect = 0.059
Identities = 32/85 (37%), Positives = 45/85 (52%), Gaps = 12/85 (14%)
Frame = +1
Query: 235 VIHIT*ENSFLLRMN---REDNVN---WFHGKISRESAEKLL-KEEGEDGVFLVRESNTS 393
V+++T L+ +N E +VN WF + R+ A+KLL EE G FLVR S +
Sbjct: 135 VVNLTTRQEGLIPLNFVAEERSVNSEDWFFENVLRKEADKLLLAEENPRGTFLVRPSEHN 194
Query: 394 PGDYVLSV--LHQGQ---VVHYQIR 453
P Y LSV G+ V HY+I+
Sbjct: 195 PNGYSLSVKDWEDGRGYHVKHYRIK 219
>UniRef50_Q96IW2 Cluster: SH2 domain-containing adapter protein D;
n=13; Mammalia|Rep: SH2 domain-containing adapter
protein D - Homo sapiens (Human)
Length = 340
Score = 40.3 bits (90), Expect = 0.059
Identities = 22/57 (38%), Positives = 32/57 (56%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGED 468
WFHG ++R AE LL ++G +LVR S T+P D LS+ +H + R E+
Sbjct: 240 WFHGPLNRADAESLL-SLCKEGSYLVRLSETNPQDCSLSLRSSQGFLHLKFARTREN 295
>UniRef50_Q15464 Cluster: SH2 domain-containing adapter protein B;
n=29; Euteleostomi|Rep: SH2 domain-containing adapter
protein B - Homo sapiens (Human)
Length = 509
Score = 40.3 bits (90), Expect = 0.059
Identities = 23/56 (41%), Positives = 31/56 (55%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGE 465
W+HG ISR AE LL+ E +LVR S TS DY LS+ +H ++ + E
Sbjct: 410 WYHGAISRGDAENLLRLCKECS-YLVRNSQTSKHDYSLSLRSNQGFMHMKLAKTKE 464
>UniRef50_Q9N597 Cluster: Phosphoinositide kinase adapter subunit
protein 1; n=2; Caenorhabditis|Rep: Phosphoinositide
kinase adapter subunit protein 1 - Caenorhabditis
elegans
Length = 522
Score = 39.9 bits (89), Expect = 0.078
Identities = 23/55 (41%), Positives = 33/55 (60%)
Frame = +1
Query: 340 LKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAFFSIEEHTTVH 504
LK E +DG+FL+R S++ VLSVLH +V H I ++ E F EH+ V+
Sbjct: 360 LKREPQDGIFLIRGSSSHGDKLVLSVLHGERVSHCLIEQNEEGWGF---EHSNVY 411
Score = 38.7 bits (86), Expect = 0.18
Identities = 45/159 (28%), Positives = 72/159 (45%), Gaps = 6/159 (3%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAFF 477
W+ R + K L ++ DG F+VR ++T PGDY LSV QV +I F
Sbjct: 20 WYWADADRSAVSKALSDQ-PDGSFIVRNAST-PGDYTLSVKFAAQVKLLRIVVKDGKCGF 77
Query: 478 SIEE--HTTVHGWILLY-NITVVI---QMDLLLGCPLSVKENHHRMSRGHREQQIYCTEQ 639
+ + H +V I + NI++ I +D+ L P+SV+ N ++ Q+ Q
Sbjct: 78 NTDSLTHDSVVRLIEFHRNISLNIFNDALDVRLLYPVSVRRNSQNGKPFFKKGQL----Q 133
Query: 640 RKRVISTWCRSYWASGLPESRRQETRTVRTAVHIAARAG 756
++ ++S W R E +R AVH+A G
Sbjct: 134 QRMILSAKNDHDW------RERLEMENLR-AVHLAFERG 165
>UniRef50_O76978 Cluster: Tyrosine kinase; n=1; Sycon raphanus|Rep:
Tyrosine kinase - Sycon raphanus
Length = 879
Score = 39.9 bits (89), Expect = 0.078
Identities = 25/59 (42%), Positives = 36/59 (61%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSVLHQGQVVHYQIRRHGEDAF 474
W+HG+ISR+ A LLK+ G+ FLVR S Y L+V +G + H+ I +H E+ F
Sbjct: 517 WYHGEISRQEATGLLKKMGD---FLVRYS-ADKEHYTLTVKMEG-IKHF-IIQHNEEGF 569
>UniRef50_Q9H6Q3 Cluster: Src-like-adapter 2; n=21;
Euteleostomi|Rep: Src-like-adapter 2 - Homo sapiens
(Human)
Length = 261
Score = 39.9 bits (89), Expect = 0.078
Identities = 21/41 (51%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDG-VFLVRESNTSPGDYVLSV 417
W + +SRE AE+LL G G FL+RES T G Y LSV
Sbjct: 94 WLYEGLSREKAEELLLLPGNPGGAFLIRESQTRRGSYSLSV 134
>UniRef50_UPI0000D555ED Cluster: PREDICTED: similar to CG32406-PA;
n=2; Endopterygota|Rep: PREDICTED: similar to CG32406-PA
- Tribolium castaneum
Length = 562
Score = 39.5 bits (88), Expect = 0.10
Identities = 34/100 (34%), Positives = 48/100 (48%), Gaps = 7/100 (7%)
Frame = +1
Query: 298 WFHGKISRESAEKLLKEEGEDGVFLVRESNTSPGDYVLSV-----LHQGQVVHYQIRR-- 456
WF I RE A ++L +E G F+VRES + PG + LS+ + HY I R
Sbjct: 429 WFQAGIPREIALEILAQEPV-GAFMVRESTSKPGCFALSLRVPRSFQPTGIAHYLIVRTN 487
Query: 457 HGEDAFFSIEEHTTVHGWILLYNITVVIQMDLLLGCPLSV 576
G +E TT+ I +++ M LL CPLS+
Sbjct: 488 KGYKIKGFTKEFTTLTSLITHHSV-----MPELLPCPLSL 522
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 799,015,828
Number of Sequences: 1657284
Number of extensions: 16110942
Number of successful extensions: 45107
Number of sequences better than 10.0: 342
Number of HSP's better than 10.0 without gapping: 42637
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 44924
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 73373641369
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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