Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= e40h0908
(829 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC051716-1|AAH51716.1| 469|Homo sapiens RUN and FYVE domain con... 102 1e-21
AF112221-1|AAF17208.1| 382|Homo sapiens rap2 interacting protei... 102 1e-21
AB020678-1|BAA74894.2| 471|Homo sapiens KIAA0871 protein protein. 102 1e-21
AY528716-1|AAT44401.1| 376|Homo sapiens antigen MU-RMS-40.17 pr... 101 2e-21
AL136233-2|CAI17235.1| 232|Homo sapiens RUN and FYVE domain con... 101 2e-21
AF461266-1|AAL67520.1| 606|Homo sapiens RUFY2 protein. 101 2e-21
AF411980-1|AAL04164.1| 590|Homo sapiens Run- and FYVE-domain co... 101 2e-21
AB040970-1|BAA96061.1| 619|Homo sapiens KIAA1537 protein protein. 101 2e-21
AK000925-1|BAA91429.1| 232|Homo sapiens protein ( Homo sapiens ... 100 7e-21
BC032571-1|AAH32571.1| 600|Homo sapiens RUN and FYVE domain con... 99 2e-20
AF361055-1|AAK50771.1| 600|Homo sapiens RUFY1 protein. 99 2e-20
AF312367-1|AAQ14554.1| 708|Homo sapiens La binding protein 1 pr... 99 2e-20
AB209507-1|BAD92744.1| 323|Homo sapiens RUN and FYVE domain-con... 99 2e-20
BC041092-1|AAH41092.1| 403|Homo sapiens RUN and FYVE domain con... 77 8e-14
U93871-1|AAB68767.1| 400|Homo sapiens RaP2 interacting protein ... 67 8e-11
CR456748-1|CAG33029.1| 405|Homo sapiens RPIP8 protein. 67 8e-11
BC006194-1|AAH06194.1| 405|Homo sapiens RaP2 interacting protei... 67 8e-11
AF055026-1|AAC09366.1| 405|Homo sapiens RaP2 interacting protei... 67 8e-11
AB209802-1|BAD93039.1| 481|Homo sapiens RaP2 interacting protei... 67 8e-11
AY033596-1|AAK52313.1| 329|Homo sapiens Rap2 binding protein 9 ... 66 1e-10
AK055233-1|BAB70882.1| 473|Homo sapiens protein ( Homo sapiens ... 66 2e-10
BX537443-1|CAD97685.1| 400|Homo sapiens hypothetical protein pr... 65 3e-10
BC022520-1|AAH22520.1| 387|Homo sapiens RPIB9 protein protein. 63 1e-09
BC064361-1|AAH64361.1| 1056|Homo sapiens pleckstrin homology dom... 41 0.006
AB002354-1|BAA20813.2| 1058|Homo sapiens KIAA0356 protein protein. 41 0.006
AK022425-1|BAB14033.1| 375|Homo sapiens protein ( Homo sapiens ... 37 0.077
BC062574-1|AAH62574.1| 614|Homo sapiens NPHP1 protein protein. 31 5.1
AJ001815-1|CAA05030.1| 732|Homo sapiens NPH1 protein. 31 5.1
AF023674-1|AAC51771.1| 731|Homo sapiens nephrocystin protein. 31 5.1
BC040441-1|AAH40441.1| 1095|Homo sapiens PLEKHM2 protein protein. 31 6.7
AL606758-2|CAH72017.1| 1019|Homo sapiens pleckstrin homology dom... 31 6.7
AL606758-1|CAH72018.1| 999|Homo sapiens pleckstrin homology dom... 31 6.7
AL450998-12|CAH70859.1| 1019|Homo sapiens pleckstrin homology do... 31 6.7
AL450998-11|CAH70860.1| 999|Homo sapiens pleckstrin homology do... 31 6.7
AL121992-10|CAI22373.1| 1019|Homo sapiens pleckstrin homology do... 31 6.7
AL121992-9|CAI22374.1| 999|Homo sapiens pleckstrin homology dom... 31 6.7
AB020649-1|BAA74865.1| 1020|Homo sapiens KIAA0842 protein protein. 31 6.7
>BC051716-1|AAH51716.1| 469|Homo sapiens RUN and FYVE domain
containing 3 protein.
Length = 469
Score = 102 bits (245), Expect = 1e-21
Identities = 51/96 (53%), Positives = 65/96 (67%)
Frame = +2
Query: 497 GPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALMLNEEAVIITGLLVGLNVVD 676
G AWLRLALMQK+L++Y++ L+ +E L E++EP+ALM+ EE II GLLVGLNV+D
Sbjct: 161 GRGRAWLRLALMQKKLSEYMKALINKKE-LLSEFYEPNALMMEEEGAIIAGLLVGLNVID 219
Query: 677 CNLCXKEEDLDSQQGGHRFLLDYXGSNSSTXLAGNG 784
N C K EDLDSQ G F + NSS G+G
Sbjct: 220 ANFCMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDG 255
Score = 89.0 bits (211), Expect = 2e-17
Identities = 41/85 (48%), Positives = 54/85 (63%)
Frame = +3
Query: 255 VKELIEQSLRFGRMLDSDHLPLHHFFIVLEHVMRHXXXXXXXXXXXXXELWDILQMVEKY 434
+K LIE +L GR LDSD+ PL FF+V+EH ++H W L++VEK
Sbjct: 80 IKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGPLELVEKL 139
Query: 435 SPEAADITASVRDLPTVKTAMGRAR 509
PEAA+ITASV+DLP +KT +GR R
Sbjct: 140 VPEAAEITASVKDLPGLKTPVGRGR 164
>AF112221-1|AAF17208.1| 382|Homo sapiens rap2 interacting protein x
protein.
Length = 382
Score = 102 bits (245), Expect = 1e-21
Identities = 51/96 (53%), Positives = 65/96 (67%)
Frame = +2
Query: 497 GPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALMLNEEAVIITGLLVGLNVVD 676
G AWLRLALMQK+L++Y++ L+ +E L E++EP+ALM+ EE II GLLVGLNV+D
Sbjct: 97 GRGRAWLRLALMQKKLSEYMKALINKKE-LLSEFYEPNALMMEEEGAIIAGLLVGLNVID 155
Query: 677 CNLCXKEEDLDSQQGGHRFLLDYXGSNSSTXLAGNG 784
N C K EDLDSQ G F + NSS G+G
Sbjct: 156 ANFCMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDG 191
Score = 90.2 bits (214), Expect = 8e-18
Identities = 42/85 (49%), Positives = 54/85 (63%)
Frame = +3
Query: 255 VKELIEQSLRFGRMLDSDHLPLHHFFIVLEHVMRHXXXXXXXXXXXXXELWDILQMVEKY 434
+K LIE +L GR LDSD+ PL FF+V+EH ++H W L++VEK
Sbjct: 16 IKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGPLELVEKL 75
Query: 435 SPEAADITASVRDLPTVKTAMGRAR 509
PEAA+ITASVRDLP +KT +GR R
Sbjct: 76 VPEAAEITASVRDLPGLKTPVGRGR 100
>AB020678-1|BAA74894.2| 471|Homo sapiens KIAA0871 protein protein.
Length = 471
Score = 102 bits (245), Expect = 1e-21
Identities = 51/96 (53%), Positives = 65/96 (67%)
Frame = +2
Query: 497 GPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALMLNEEAVIITGLLVGLNVVD 676
G AWLRLALMQK+L++Y++ L+ +E L E++EP+ALM+ EE II GLLVGLNV+D
Sbjct: 163 GRGRAWLRLALMQKKLSEYMKALINKKE-LLSEFYEPNALMMEEEGAIIAGLLVGLNVID 221
Query: 677 CNLCXKEEDLDSQQGGHRFLLDYXGSNSSTXLAGNG 784
N C K EDLDSQ G F + NSS G+G
Sbjct: 222 ANFCMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDG 257
Score = 89.0 bits (211), Expect = 2e-17
Identities = 41/85 (48%), Positives = 54/85 (63%)
Frame = +3
Query: 255 VKELIEQSLRFGRMLDSDHLPLHHFFIVLEHVMRHXXXXXXXXXXXXXELWDILQMVEKY 434
+K LIE +L GR LDSD+ PL FF+V+EH ++H W L++VEK
Sbjct: 82 IKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGPLELVEKL 141
Query: 435 SPEAADITASVRDLPTVKTAMGRAR 509
PEAA+ITASV+DLP +KT +GR R
Sbjct: 142 VPEAAEITASVKDLPGLKTPVGRGR 166
>AY528716-1|AAT44401.1| 376|Homo sapiens antigen MU-RMS-40.17
protein.
Length = 376
Score = 101 bits (243), Expect = 2e-21
Identities = 49/75 (65%), Positives = 57/75 (76%)
Frame = +2
Query: 497 GPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALMLNEEAVIITGLLVGLNVVD 676
G AWLRLALMQK++ADYLR L+ R D L E++E HALM+ EE +I GLLVGLNV+D
Sbjct: 103 GRARAWLRLALMQKKMADYLRCLIIQR-DLLSEFYEYHALMMEEEGAVIVGLLVGLNVID 161
Query: 677 CNLCXKEEDLDSQQG 721
NLC K EDLDSQ G
Sbjct: 162 ANLCVKGEDLDSQVG 176
Score = 89.0 bits (211), Expect = 2e-17
Identities = 42/85 (49%), Positives = 55/85 (64%)
Frame = +3
Query: 255 VKELIEQSLRFGRMLDSDHLPLHHFFIVLEHVMRHXXXXXXXXXXXXXELWDILQMVEKY 434
+K LIE +L FGR LDSD+ PL FF+V+EH ++H +W L++VEK
Sbjct: 22 IKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVRKSFLSYNKTIWGPLELVEKL 81
Query: 435 SPEAADITASVRDLPTVKTAMGRAR 509
PEA +I ASVRDLP +KT +GRAR
Sbjct: 82 YPEAEEIGASVRDLPGLKTPLGRAR 106
>AL136233-2|CAI17235.1| 232|Homo sapiens RUN and FYVE domain
containing 2 protein.
Length = 232
Score = 101 bits (243), Expect = 2e-21
Identities = 49/75 (65%), Positives = 57/75 (76%)
Frame = +2
Query: 497 GPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALMLNEEAVIITGLLVGLNVVD 676
G AWLRLALMQK++ADYLR L+ R D L E++E HALM+ EE +I GLLVGLNV+D
Sbjct: 103 GRARAWLRLALMQKKMADYLRCLIIQR-DLLSEFYEYHALMMEEEGAVIVGLLVGLNVID 161
Query: 677 CNLCXKEEDLDSQQG 721
NLC K EDLDSQ G
Sbjct: 162 ANLCVKGEDLDSQVG 176
Score = 89.0 bits (211), Expect = 2e-17
Identities = 42/85 (49%), Positives = 55/85 (64%)
Frame = +3
Query: 255 VKELIEQSLRFGRMLDSDHLPLHHFFIVLEHVMRHXXXXXXXXXXXXXELWDILQMVEKY 434
+K LIE +L FGR LDSD+ PL FF+V+EH ++H +W L++VEK
Sbjct: 22 IKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVRKSFLSYNKTIWGPLELVEKL 81
Query: 435 SPEAADITASVRDLPTVKTAMGRAR 509
PEA +I ASVRDLP +KT +GRAR
Sbjct: 82 YPEAEEIGASVRDLPGLKTPLGRAR 106
>AF461266-1|AAL67520.1| 606|Homo sapiens RUFY2 protein.
Length = 606
Score = 101 bits (243), Expect = 2e-21
Identities = 49/75 (65%), Positives = 57/75 (76%)
Frame = +2
Query: 497 GPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALMLNEEAVIITGLLVGLNVVD 676
G AWLRLALMQK++ADYLR L+ R D L E++E HALM+ EE +I GLLVGLNV+D
Sbjct: 103 GRARAWLRLALMQKKMADYLRCLIIQR-DLLSEFYEYHALMMEEEGAVIVGLLVGLNVID 161
Query: 677 CNLCXKEEDLDSQQG 721
NLC K EDLDSQ G
Sbjct: 162 ANLCVKGEDLDSQVG 176
Score = 89.0 bits (211), Expect = 2e-17
Identities = 42/85 (49%), Positives = 55/85 (64%)
Frame = +3
Query: 255 VKELIEQSLRFGRMLDSDHLPLHHFFIVLEHVMRHXXXXXXXXXXXXXELWDILQMVEKY 434
+K LIE +L FGR LDSD+ PL FF+V+EH ++H +W L++VEK
Sbjct: 22 IKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVRKSFLSYNKTIWGPLELVEKL 81
Query: 435 SPEAADITASVRDLPTVKTAMGRAR 509
PEA +I ASVRDLP +KT +GRAR
Sbjct: 82 YPEAEEIGASVRDLPGLKTPLGRAR 106
>AF411980-1|AAL04164.1| 590|Homo sapiens Run- and FYVE-domain
containing protein Rabip4R protein.
Length = 590
Score = 101 bits (243), Expect = 2e-21
Identities = 49/75 (65%), Positives = 57/75 (76%)
Frame = +2
Query: 497 GPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALMLNEEAVIITGLLVGLNVVD 676
G AWLRLALMQK++ADYLR L+ R D L E++E HALM+ EE +I GLLVGLNV+D
Sbjct: 87 GRARAWLRLALMQKKMADYLRCLIIQR-DLLSEFYEYHALMMEEEGAVIVGLLVGLNVID 145
Query: 677 CNLCXKEEDLDSQQG 721
NLC K EDLDSQ G
Sbjct: 146 ANLCVKGEDLDSQVG 160
Score = 89.0 bits (211), Expect = 2e-17
Identities = 42/85 (49%), Positives = 55/85 (64%)
Frame = +3
Query: 255 VKELIEQSLRFGRMLDSDHLPLHHFFIVLEHVMRHXXXXXXXXXXXXXELWDILQMVEKY 434
+K LIE +L FGR LDSD+ PL FF+V+EH ++H +W L++VEK
Sbjct: 6 IKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVRKSFLSYNKTIWGPLELVEKL 65
Query: 435 SPEAADITASVRDLPTVKTAMGRAR 509
PEA +I ASVRDLP +KT +GRAR
Sbjct: 66 YPEAEEIGASVRDLPGLKTPLGRAR 90
>AB040970-1|BAA96061.1| 619|Homo sapiens KIAA1537 protein protein.
Length = 619
Score = 101 bits (243), Expect = 2e-21
Identities = 49/75 (65%), Positives = 57/75 (76%)
Frame = +2
Query: 497 GPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALMLNEEAVIITGLLVGLNVVD 676
G AWLRLALMQK++ADYLR L+ R D L E++E HALM+ EE +I GLLVGLNV+D
Sbjct: 116 GRARAWLRLALMQKKMADYLRCLIIQR-DLLSEFYEYHALMMEEEGAVIVGLLVGLNVID 174
Query: 677 CNLCXKEEDLDSQQG 721
NLC K EDLDSQ G
Sbjct: 175 ANLCVKGEDLDSQVG 189
Score = 89.0 bits (211), Expect = 2e-17
Identities = 42/85 (49%), Positives = 55/85 (64%)
Frame = +3
Query: 255 VKELIEQSLRFGRMLDSDHLPLHHFFIVLEHVMRHXXXXXXXXXXXXXELWDILQMVEKY 434
+K LIE +L FGR LDSD+ PL FF+V+EH ++H +W L++VEK
Sbjct: 35 IKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVRKSFLSYNKTIWGPLELVEKL 94
Query: 435 SPEAADITASVRDLPTVKTAMGRAR 509
PEA +I ASVRDLP +KT +GRAR
Sbjct: 95 YPEAEEIGASVRDLPGLKTPLGRAR 119
Score = 30.7 bits (66), Expect = 6.7
Identities = 12/27 (44%), Positives = 18/27 (66%)
Frame = +1
Query: 172 RPQKTYNSKTRDPVVIERSNLVNISKL 252
RP T+DP +ER+NL+N++KL
Sbjct: 7 RPGARTGPATKDPTAVERANLLNMAKL 33
>AK000925-1|BAA91429.1| 232|Homo sapiens protein ( Homo sapiens
cDNA FLJ10063 fis, clone HEMBA1001446. ).
Length = 232
Score = 100 bits (239), Expect = 7e-21
Identities = 48/75 (64%), Positives = 57/75 (76%)
Frame = +2
Query: 497 GPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALMLNEEAVIITGLLVGLNVVD 676
G AWLRLALMQK++ADYLR L+ R D L E++E HALM+ EE +I GLLVGLNV+D
Sbjct: 103 GRARAWLRLALMQKKMADYLRCLIIQR-DLLSEFYEYHALMMEEEGAVIVGLLVGLNVID 161
Query: 677 CNLCXKEEDLDSQQG 721
NLC K EDLDS+ G
Sbjct: 162 ANLCVKGEDLDSRVG 176
Score = 89.0 bits (211), Expect = 2e-17
Identities = 42/85 (49%), Positives = 55/85 (64%)
Frame = +3
Query: 255 VKELIEQSLRFGRMLDSDHLPLHHFFIVLEHVMRHXXXXXXXXXXXXXELWDILQMVEKY 434
+K LIE +L FGR LDSD+ PL FF+V+EH ++H +W L++VEK
Sbjct: 22 IKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVRKSFLSYNKTIWGPLELVEKL 81
Query: 435 SPEAADITASVRDLPTVKTAMGRAR 509
PEA +I ASVRDLP +KT +GRAR
Sbjct: 82 YPEAEEIGASVRDLPGLKTPLGRAR 106
>BC032571-1|AAH32571.1| 600|Homo sapiens RUN and FYVE domain
containing 1 protein.
Length = 600
Score = 99.1 bits (236), Expect = 2e-20
Identities = 46/75 (61%), Positives = 59/75 (78%)
Frame = +2
Query: 497 GPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALMLNEEAVIITGLLVGLNVVD 676
G AWL LALMQK+LADYL++L++++ L E++EP ALM+ EE ++I GLLVGLNV+D
Sbjct: 97 GRGRAWLYLALMQKKLADYLKVLIDNKH-LLSEFYEPEALMMEEEGMVIVGLLVGLNVLD 155
Query: 677 CNLCXKEEDLDSQQG 721
NLC K EDLDSQ G
Sbjct: 156 ANLCLKGEDLDSQVG 170
Score = 82.6 bits (195), Expect = 2e-15
Identities = 37/85 (43%), Positives = 53/85 (62%)
Frame = +3
Query: 255 VKELIEQSLRFGRMLDSDHLPLHHFFIVLEHVMRHXXXXXXXXXXXXXELWDILQMVEKY 434
+K L++ +L GR LD+DH PL FF+V+EH ++H + L++VEK
Sbjct: 16 IKVLLQSALSLGRSLDADHAPLQQFFVVMEHCLKHGLKVKKSFIGQNKSFFGPLELVEKL 75
Query: 435 SPEAADITASVRDLPTVKTAMGRAR 509
PEA+DI SVR+LP +KTA+GR R
Sbjct: 76 CPEASDIATSVRNLPELKTAVGRGR 100
>AF361055-1|AAK50771.1| 600|Homo sapiens RUFY1 protein.
Length = 600
Score = 99.1 bits (236), Expect = 2e-20
Identities = 46/75 (61%), Positives = 59/75 (78%)
Frame = +2
Query: 497 GPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALMLNEEAVIITGLLVGLNVVD 676
G AWL LALMQK+LADYL++L++++ L E++EP ALM+ EE ++I GLLVGLNV+D
Sbjct: 97 GRGRAWLYLALMQKKLADYLKVLIDNKH-LLSEFYEPEALMMEEEGMVIVGLLVGLNVLD 155
Query: 677 CNLCXKEEDLDSQQG 721
NLC K EDLDSQ G
Sbjct: 156 ANLCLKGEDLDSQVG 170
Score = 82.6 bits (195), Expect = 2e-15
Identities = 37/85 (43%), Positives = 53/85 (62%)
Frame = +3
Query: 255 VKELIEQSLRFGRMLDSDHLPLHHFFIVLEHVMRHXXXXXXXXXXXXXELWDILQMVEKY 434
+K L++ +L GR LD+DH PL FF+V+EH ++H + L++VEK
Sbjct: 16 IKVLLQSALSLGRSLDADHAPLQQFFVVMEHCLKHGLKVKKSFIGQNKSFFGPLELVEKL 75
Query: 435 SPEAADITASVRDLPTVKTAMGRAR 509
PEA+DI SVR+LP +KTA+GR R
Sbjct: 76 CPEASDIATSVRNLPELKTAVGRGR 100
>AF312367-1|AAQ14554.1| 708|Homo sapiens La binding protein 1
protein.
Length = 708
Score = 99.1 bits (236), Expect = 2e-20
Identities = 46/75 (61%), Positives = 59/75 (78%)
Frame = +2
Query: 497 GPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALMLNEEAVIITGLLVGLNVVD 676
G AWL LALMQK+LADYL++L++++ L E++EP ALM+ EE ++I GLLVGLNV+D
Sbjct: 205 GRGRAWLYLALMQKKLADYLKVLIDNKH-LLSEFYEPEALMMEEEGMVIVGLLVGLNVLD 263
Query: 677 CNLCXKEEDLDSQQG 721
NLC K EDLDSQ G
Sbjct: 264 ANLCLKGEDLDSQVG 278
Score = 82.6 bits (195), Expect = 2e-15
Identities = 37/85 (43%), Positives = 53/85 (62%)
Frame = +3
Query: 255 VKELIEQSLRFGRMLDSDHLPLHHFFIVLEHVMRHXXXXXXXXXXXXXELWDILQMVEKY 434
+K L++ +L GR LD+DH PL FF+V+EH ++H + L++VEK
Sbjct: 124 IKVLLQSALSLGRSLDADHAPLQQFFVVMEHCLKHGLKVKKSFIGQNKSFFGPLELVEKL 183
Query: 435 SPEAADITASVRDLPTVKTAMGRAR 509
PEA+DI SVR+LP +KTA+GR R
Sbjct: 184 CPEASDIATSVRNLPELKTAVGRGR 208
>AB209507-1|BAD92744.1| 323|Homo sapiens RUN and FYVE
domain-containing 1 variant protein.
Length = 323
Score = 99.1 bits (236), Expect = 2e-20
Identities = 46/75 (61%), Positives = 59/75 (78%)
Frame = +2
Query: 497 GPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALMLNEEAVIITGLLVGLNVVD 676
G AWL LALMQK+LADYL++L++++ L E++EP ALM+ EE ++I GLLVGLNV+D
Sbjct: 116 GRGRAWLYLALMQKKLADYLKVLIDNKH-LLSEFYEPEALMMEEEGMVIVGLLVGLNVLD 174
Query: 677 CNLCXKEEDLDSQQG 721
NLC K EDLDSQ G
Sbjct: 175 ANLCLKGEDLDSQVG 189
Score = 82.6 bits (195), Expect = 2e-15
Identities = 37/85 (43%), Positives = 53/85 (62%)
Frame = +3
Query: 255 VKELIEQSLRFGRMLDSDHLPLHHFFIVLEHVMRHXXXXXXXXXXXXXELWDILQMVEKY 434
+K L++ +L GR LD+DH PL FF+V+EH ++H + L++VEK
Sbjct: 35 IKVLLQSALSLGRSLDADHAPLQQFFVVMEHCLKHGLKVKKSFIGQNKSFFGPLELVEKL 94
Query: 435 SPEAADITASVRDLPTVKTAMGRAR 509
PEA+DI SVR+LP +KTA+GR R
Sbjct: 95 CPEASDIATSVRNLPELKTAVGRGR 119
>BC041092-1|AAH41092.1| 403|Homo sapiens RUN and FYVE domain
containing 2 protein.
Length = 403
Score = 77.0 bits (181), Expect = 8e-14
Identities = 36/75 (48%), Positives = 47/75 (62%)
Frame = +3
Query: 255 VKELIEQSLRFGRMLDSDHLPLHHFFIVLEHVMRHXXXXXXXXXXXXXELWDILQMVEKY 434
+K LIE +L FGR LDSD+ PL FF+V+EH ++H +W L++VEK
Sbjct: 22 IKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVRKSFLSYNKTIWGPLELVEKL 81
Query: 435 SPEAADITASVRDLP 479
PEA +I ASVRDLP
Sbjct: 82 YPEAEEIGASVRDLP 96
Score = 69.7 bits (163), Expect = 1e-11
Identities = 36/74 (48%), Positives = 47/74 (63%), Gaps = 1/74 (1%)
Frame = +2
Query: 503 RSAWLRLALMQKRLADYLRILLEHRE-DTLEEYFEPHALMLNEEAVIITGLLVGLNVVDC 679
++ W L L++K + I R+ L E++E HALM+ EE +I GLLVGLNV+D
Sbjct: 69 KTIWGPLELVEKLYPEAEEIGASVRDLPGLNEFYEYHALMMEEEGAVIVGLLVGLNVIDA 128
Query: 680 NLCXKEEDLDSQQG 721
NLC K EDLDSQ G
Sbjct: 129 NLCVKGEDLDSQVG 142
>U93871-1|AAB68767.1| 400|Homo sapiens RaP2 interacting protein 8
protein.
Length = 400
Score = 66.9 bits (156), Expect = 8e-11
Identities = 29/83 (34%), Positives = 50/83 (60%)
Frame = +2
Query: 467 QRSSNCEDSNGPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALMLNEEAVIIT 646
+ N + AW+R+ALM+KR+++Y+ L T +++ A+ML +EA I+T
Sbjct: 108 ENMENISTARAKGRAWIRVALMEKRMSEYITTALRDTRTT-RRFYDSGAIMLRDEATILT 166
Query: 647 GLLVGLNVVDCNLCXKEEDLDSQ 715
G+L+GL+ +D + C K E LD +
Sbjct: 167 GMLIGLSAIDFSFCLKGEVLDGK 189
>CR456748-1|CAG33029.1| 405|Homo sapiens RPIP8 protein.
Length = 405
Score = 66.9 bits (156), Expect = 8e-11
Identities = 29/83 (34%), Positives = 50/83 (60%)
Frame = +2
Query: 467 QRSSNCEDSNGPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALMLNEEAVIIT 646
+ N + AW+R+ALM+KR+++Y+ L T +++ A+ML +EA I+T
Sbjct: 113 ENMENISTARAKGRAWIRVALMEKRMSEYITTALRDTRTT-RRFYDSGAIMLRDEATILT 171
Query: 647 GLLVGLNVVDCNLCXKEEDLDSQ 715
G+L+GL+ +D + C K E LD +
Sbjct: 172 GMLIGLSAIDFSFCLKGEVLDGK 194
>BC006194-1|AAH06194.1| 405|Homo sapiens RaP2 interacting protein 8
protein.
Length = 405
Score = 66.9 bits (156), Expect = 8e-11
Identities = 29/83 (34%), Positives = 50/83 (60%)
Frame = +2
Query: 467 QRSSNCEDSNGPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALMLNEEAVIIT 646
+ N + AW+R+ALM+KR+++Y+ L T +++ A+ML +EA I+T
Sbjct: 113 ENMENISTARAKGRAWIRVALMEKRMSEYITTALRDTRTT-RRFYDSGAIMLRDEATILT 171
Query: 647 GLLVGLNVVDCNLCXKEEDLDSQ 715
G+L+GL+ +D + C K E LD +
Sbjct: 172 GMLIGLSAIDFSFCLKGEVLDGK 194
>AF055026-1|AAC09366.1| 405|Homo sapiens RaP2 interacting protein 8
protein.
Length = 405
Score = 66.9 bits (156), Expect = 8e-11
Identities = 29/83 (34%), Positives = 50/83 (60%)
Frame = +2
Query: 467 QRSSNCEDSNGPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALMLNEEAVIIT 646
+ N + AW+R+ALM+KR+++Y+ L T +++ A+ML +EA I+T
Sbjct: 113 ENMENISTARAKGRAWIRVALMEKRMSEYITTALRDTRTT-RRFYDSGAIMLRDEATILT 171
Query: 647 GLLVGLNVVDCNLCXKEEDLDSQ 715
G+L+GL+ +D + C K E LD +
Sbjct: 172 GMLIGLSAIDFSFCLKGEVLDGK 194
>AB209802-1|BAD93039.1| 481|Homo sapiens RaP2 interacting protein 8
variant protein.
Length = 481
Score = 66.9 bits (156), Expect = 8e-11
Identities = 29/83 (34%), Positives = 50/83 (60%)
Frame = +2
Query: 467 QRSSNCEDSNGPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALMLNEEAVIIT 646
+ N + AW+R+ALM+KR+++Y+ L T +++ A+ML +EA I+T
Sbjct: 148 ENMENISTARAKGRAWIRVALMEKRMSEYITTALRDTRTT-RRFYDSGAIMLRDEATILT 206
Query: 647 GLLVGLNVVDCNLCXKEEDLDSQ 715
G+L+GL+ +D + C K E LD +
Sbjct: 207 GMLIGLSAIDFSFCLKGEVLDGK 229
>AY033596-1|AAK52313.1| 329|Homo sapiens Rap2 binding protein 9
protein.
Length = 329
Score = 66.1 bits (154), Expect = 1e-10
Identities = 33/93 (35%), Positives = 53/93 (56%)
Frame = +2
Query: 467 QRSSNCEDSNGPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALMLNEEAVIIT 646
+ N S AW+R+ALM+K L++Y+ L + T ++E A++L EEA ++
Sbjct: 35 ENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTT-RRFYEDGAIVLGEEASMLA 93
Query: 647 GLLVGLNVVDCNLCXKEEDLDSQQGGHRFLLDY 745
G+L+GLN +D + C K E LD G ++DY
Sbjct: 94 GMLLGLNAIDFSFCLKGEGLD---GSFPAVIDY 123
>AK055233-1|BAB70882.1| 473|Homo sapiens protein ( Homo sapiens
cDNA FLJ30671 fis, clone FCBBF1000687, moderately
similar to Mus musculus Rap2 interacting protein 8
(RPIP8) mRNA. ).
Length = 473
Score = 65.7 bits (153), Expect = 2e-10
Identities = 33/93 (35%), Positives = 53/93 (56%)
Frame = +2
Query: 467 QRSSNCEDSNGPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALMLNEEAVIIT 646
+ N S AW+R+ALM+K L++Y+ L + T ++E A++L EEA ++
Sbjct: 130 ENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTT-RRFYEDGAIVLGEEANMLA 188
Query: 647 GLLVGLNVVDCNLCXKEEDLDSQQGGHRFLLDY 745
G+L+GLN +D + C K E LD G ++DY
Sbjct: 189 GMLLGLNAIDFSFCLKGEGLD---GSFPAVIDY 218
>BX537443-1|CAD97685.1| 400|Homo sapiens hypothetical protein
protein.
Length = 400
Score = 65.3 bits (152), Expect = 3e-10
Identities = 28/83 (33%), Positives = 50/83 (60%)
Frame = +2
Query: 467 QRSSNCEDSNGPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALMLNEEAVIIT 646
+ N + AW+R+AL++KR+++Y+ L T +++ A+ML +EA I+T
Sbjct: 108 ENMENISTARAKGRAWIRVALVEKRMSEYITTALRDTRTT-RRFYDSGAIMLRDEATILT 166
Query: 647 GLLVGLNVVDCNLCXKEEDLDSQ 715
G+L+GL+ +D + C K E LD +
Sbjct: 167 GMLIGLSAIDFSFCLKGEVLDGK 189
>BC022520-1|AAH22520.1| 387|Homo sapiens RPIB9 protein protein.
Length = 387
Score = 62.9 bits (146), Expect = 1e-09
Identities = 32/93 (34%), Positives = 52/93 (55%)
Frame = +2
Query: 467 QRSSNCEDSNGPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALMLNEEAVIIT 646
+ N S AW+R+ALM+K L++Y+ L + T ++E A++L EEA ++
Sbjct: 113 ENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTT-RRFYEDGAIVLGEEANMLA 171
Query: 647 GLLVGLNVVDCNLCXKEEDLDSQQGGHRFLLDY 745
G+L+GLN +D + C K LD G ++DY
Sbjct: 172 GMLLGLNAIDFSFCLKGGGLD---GSFPAVIDY 201
>BC064361-1|AAH64361.1| 1056|Homo sapiens pleckstrin homology domain
containing, family M (with RUN domain) member 1 protein.
Length = 1056
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/68 (36%), Positives = 37/68 (54%), Gaps = 1/68 (1%)
Frame = +2
Query: 509 AWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALMLN-EEAVIITGLLVGLNVVDCNL 685
AWLRLAL + YL++LL+ + L EY++P AL+ + EE + L GL + L
Sbjct: 120 AWLRLALNDGLMECYLKLLLQ-EQARLHEYYQPTALLRDAEEGEFLLSFLQGLTSLSFEL 178
Query: 686 CXKEEDLD 709
K L+
Sbjct: 179 SYKSAILN 186
>AB002354-1|BAA20813.2| 1058|Homo sapiens KIAA0356 protein protein.
Length = 1058
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/68 (36%), Positives = 37/68 (54%), Gaps = 1/68 (1%)
Frame = +2
Query: 509 AWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALMLN-EEAVIITGLLVGLNVVDCNL 685
AWLRLAL + YL++LL+ + L EY++P AL+ + EE + L GL + L
Sbjct: 122 AWLRLALNDGLMECYLKLLLQ-EQARLHEYYQPTALLRDAEEGEFLLSFLQGLTSLSFEL 180
Query: 686 CXKEEDLD 709
K L+
Sbjct: 181 SYKSAILN 188
>AK022425-1|BAB14033.1| 375|Homo sapiens protein ( Homo sapiens
cDNA FLJ12363 fis, clone MAMMA1002380. ).
Length = 375
Score = 37.1 bits (82), Expect = 0.077
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 1/74 (1%)
Frame = +2
Query: 497 GPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALMLNEE-AVIITGLLVGLNVV 673
G AWLR AL + L YL +LL R L ++E + +++EE + ++ + GLN +
Sbjct: 113 GRGRAWLRCALNEHSLERYLHMLLADR-CRLSTFYEDWSFVMDEERSSMLPTMAAGLNSI 171
Query: 674 DCNLCXKEEDLDSQ 715
+ +DLD Q
Sbjct: 172 LFAINIDNKDLDGQ 185
>BC062574-1|AAH62574.1| 614|Homo sapiens NPHP1 protein protein.
Length = 614
Score = 31.1 bits (67), Expect = 5.1
Identities = 14/35 (40%), Positives = 20/35 (57%)
Frame = -1
Query: 214 QRDREFLSYMFFVVAISEVLAIFHLLKMKIFRWDE 110
+RD+EFL F +V VL + H ++ FRW E
Sbjct: 524 KRDKEFLKSTFLLVYHDCVLPLLHSTRLPPFRWAE 558
>AJ001815-1|CAA05030.1| 732|Homo sapiens NPH1 protein.
Length = 732
Score = 31.1 bits (67), Expect = 5.1
Identities = 14/35 (40%), Positives = 20/35 (57%)
Frame = -1
Query: 214 QRDREFLSYMFFVVAISEVLAIFHLLKMKIFRWDE 110
+RD+EFL F +V VL + H ++ FRW E
Sbjct: 642 KRDKEFLKSTFLLVYHDCVLPLLHSTRLPPFRWAE 676
>AF023674-1|AAC51771.1| 731|Homo sapiens nephrocystin protein.
Length = 731
Score = 31.1 bits (67), Expect = 5.1
Identities = 14/35 (40%), Positives = 20/35 (57%)
Frame = -1
Query: 214 QRDREFLSYMFFVVAISEVLAIFHLLKMKIFRWDE 110
+RD+EFL F +V VL + H ++ FRW E
Sbjct: 641 KRDKEFLKSTFLLVYHDCVLPLLHSTRLPPFRWAE 675
>BC040441-1|AAH40441.1| 1095|Homo sapiens PLEKHM2 protein protein.
Length = 1095
Score = 30.7 bits (66), Expect = 6.7
Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Frame = +2
Query: 497 GPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALML-NEEAVIITGLLVGLNVV 673
G AWL LAL + L YLR+ E+ L +Y+ +AL+ ++ + L+ GL +
Sbjct: 167 GRSRAWLYLALNENSLESYLRLFQENL-GLLHKYYVKNALVCSHDHLTLFLTLVSGLEFI 225
>AL606758-2|CAH72017.1| 1019|Homo sapiens pleckstrin homology domain
containing, family M (with RUN domain) member 2 protein.
Length = 1019
Score = 30.7 bits (66), Expect = 6.7
Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Frame = +2
Query: 497 GPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALML-NEEAVIITGLLVGLNVV 673
G AWL LAL + L YLR+ E+ L +Y+ +AL+ ++ + L+ GL +
Sbjct: 91 GRSRAWLYLALNENSLESYLRLFQENL-GLLHKYYVKNALVCSHDHLTLFLTLVSGLEFI 149
>AL606758-1|CAH72018.1| 999|Homo sapiens pleckstrin homology domain
containing, family M (with RUN domain) member 2 protein.
Length = 999
Score = 30.7 bits (66), Expect = 6.7
Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Frame = +2
Query: 497 GPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALML-NEEAVIITGLLVGLNVV 673
G AWL LAL + L YLR+ E+ L +Y+ +AL+ ++ + L+ GL +
Sbjct: 91 GRSRAWLYLALNENSLESYLRLFQENL-GLLHKYYVKNALVCSHDHLTLFLTLVSGLEFI 149
>AL450998-12|CAH70859.1| 1019|Homo sapiens pleckstrin homology
domain containing, family M (with RUN domain) member 2
protein.
Length = 1019
Score = 30.7 bits (66), Expect = 6.7
Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Frame = +2
Query: 497 GPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALML-NEEAVIITGLLVGLNVV 673
G AWL LAL + L YLR+ E+ L +Y+ +AL+ ++ + L+ GL +
Sbjct: 91 GRSRAWLYLALNENSLESYLRLFQENL-GLLHKYYVKNALVCSHDHLTLFLTLVSGLEFI 149
>AL450998-11|CAH70860.1| 999|Homo sapiens pleckstrin homology
domain containing, family M (with RUN domain) member 2
protein.
Length = 999
Score = 30.7 bits (66), Expect = 6.7
Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Frame = +2
Query: 497 GPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALML-NEEAVIITGLLVGLNVV 673
G AWL LAL + L YLR+ E+ L +Y+ +AL+ ++ + L+ GL +
Sbjct: 91 GRSRAWLYLALNENSLESYLRLFQENL-GLLHKYYVKNALVCSHDHLTLFLTLVSGLEFI 149
>AL121992-10|CAI22373.1| 1019|Homo sapiens pleckstrin homology
domain containing, family M (with RUN domain) member 2
protein.
Length = 1019
Score = 30.7 bits (66), Expect = 6.7
Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Frame = +2
Query: 497 GPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALML-NEEAVIITGLLVGLNVV 673
G AWL LAL + L YLR+ E+ L +Y+ +AL+ ++ + L+ GL +
Sbjct: 91 GRSRAWLYLALNENSLESYLRLFQENL-GLLHKYYVKNALVCSHDHLTLFLTLVSGLEFI 149
>AL121992-9|CAI22374.1| 999|Homo sapiens pleckstrin homology domain
containing, family M (with RUN domain) member 2 protein.
Length = 999
Score = 30.7 bits (66), Expect = 6.7
Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Frame = +2
Query: 497 GPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALML-NEEAVIITGLLVGLNVV 673
G AWL LAL + L YLR+ E+ L +Y+ +AL+ ++ + L+ GL +
Sbjct: 91 GRSRAWLYLALNENSLESYLRLFQENL-GLLHKYYVKNALVCSHDHLTLFLTLVSGLEFI 149
>AB020649-1|BAA74865.1| 1020|Homo sapiens KIAA0842 protein protein.
Length = 1020
Score = 30.7 bits (66), Expect = 6.7
Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Frame = +2
Query: 497 GPRSAWLRLALMQKRLADYLRILLEHREDTLEEYFEPHALML-NEEAVIITGLLVGLNVV 673
G AWL LAL + L YLR+ E+ L +Y+ +AL+ ++ + L+ GL +
Sbjct: 92 GRSRAWLYLALNENSLESYLRLFQENL-GLLHKYYVKNALVCSHDHLTLFLTLVSGLEFI 150
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 108,288,762
Number of Sequences: 237096
Number of extensions: 2064307
Number of successful extensions: 4306
Number of sequences better than 10.0: 37
Number of HSP's better than 10.0 without gapping: 4116
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4278
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10370898348
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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