Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= e40h0881
(852 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC103934-1|AAI03935.1| 923|Homo sapiens aldehyde dehydrogenase ... 145 2e-34
AK095827-1|BAC04634.1| 752|Homo sapiens protein ( Homo sapiens ... 145 2e-34
BC027241-1|AAH27241.1| 505|Homo sapiens ALDH1L1 protein protein. 136 1e-31
AK222694-1|BAD96414.1| 902|Homo sapiens formyltetrahydrofolate ... 136 1e-31
AK222535-1|BAD96255.1| 902|Homo sapiens formyltetrahydrofolate ... 136 1e-31
AB209299-1|BAD92536.1| 954|Homo sapiens aldehyde dehydrogenase ... 136 1e-31
AF052732-1|AAC35000.1| 902|Homo sapiens 10-formyltetrahydrofola... 133 9e-31
AL133015-1|CAB61356.1| 240|Homo sapiens hypothetical protein pr... 100 8e-21
BC033687-1|AAH33687.1| 304|Homo sapiens mitochondrial methionyl... 45 3e-04
BC016630-1|AAH16630.2| 304|Homo sapiens mitochondrial methionyl... 45 3e-04
AK055688-1|BAB70984.1| 304|Homo sapiens protein ( Homo sapiens ... 45 3e-04
X54199-1|CAA38119.1| 1010|Homo sapiens glycinamide ribonucleotid... 38 0.035
M32082-1|AAA60077.1| 302|Homo sapiens GART protein. 38 0.035
BC107712-1|AAI07713.1| 1010|Homo sapiens phosphoribosylglycinami... 38 0.035
AB208785-1|BAD92022.1| 1046|Homo sapiens phosphoribosylglycinami... 38 0.035
Z19585-1|CAA79635.1| 961|Homo sapiens thrombospondin-4 protein. 30 9.3
>BC103934-1|AAI03935.1| 923|Homo sapiens aldehyde dehydrogenase 1
family, member L2 protein.
Length = 923
Score = 145 bits (351), Expect = 2e-34
Identities = 62/81 (76%), Positives = 72/81 (88%)
Frame = +3
Query: 513 EQYKSVNADLNVLPFCTQFIPMEVITAPKYESICYHPSILPRHRGASSVNWTLIEGDTTC 692
E Y+SV A+LNVLPFCTQFIPM++I +PK+ SI YHPSILPRHRGAS++NWTLI GD
Sbjct: 93 EAYRSVGAELNVLPFCTQFIPMDIIDSPKHGSIIYHPSILPRHRGASAINWTLIMGDKKA 152
Query: 693 GFSIFWADDGLDTGPILLQKS 755
GFS+FWADDGLDTGPILLQ+S
Sbjct: 153 GFSVFWADDGLDTGPILLQRS 173
Score = 87.0 bits (206), Expect = 8e-17
Identities = 36/71 (50%), Positives = 51/71 (71%)
Frame = +1
Query: 295 KKSLRVAIIGQSTFAAEVFKLIQRDGHEVVGVFTIPDKGNREDPLATIAAQNGKPVYKYK 474
K L++A+IGQS F EV+ ++++GH VVGVFT+PDK + DPLA A ++G PV+K
Sbjct: 20 KNKLKLALIGQSLFGQEVYSHLRKEGHRVVGVFTVPDKDGKADPLALAAEKDGTPVFKLP 79
Query: 475 SWRIKGQVIPE 507
WR+KG+ I E
Sbjct: 80 KWRVKGKTIKE 90
Score = 45.6 bits (103), Expect = 2e-04
Identities = 17/27 (62%), Positives = 24/27 (88%)
Frame = +2
Query: 770 DDTVDTIYNKFLYPEGIKALAEAVNMV 850
+DTVD +YN+FL+PEGIKA+ EAV ++
Sbjct: 179 NDTVDALYNRFLFPEGIKAMVEAVQLI 205
>AK095827-1|BAC04634.1| 752|Homo sapiens protein ( Homo sapiens
cDNA FLJ38508 fis, clone HCHON2000322, moderately
similar to 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE (EC
1.5.1.6). ).
Length = 752
Score = 145 bits (351), Expect = 2e-34
Identities = 62/81 (76%), Positives = 72/81 (88%)
Frame = +3
Query: 513 EQYKSVNADLNVLPFCTQFIPMEVITAPKYESICYHPSILPRHRGASSVNWTLIEGDTTC 692
E Y+SV A+LNVLPFCTQFIPM++I +PK+ SI YHPSILPRHRGAS++NWTLI GD
Sbjct: 93 EAYRSVGAELNVLPFCTQFIPMDIIDSPKHGSIIYHPSILPRHRGASAINWTLIMGDKKA 152
Query: 693 GFSIFWADDGLDTGPILLQKS 755
GFS+FWADDGLDTGPILLQ+S
Sbjct: 153 GFSVFWADDGLDTGPILLQRS 173
Score = 87.0 bits (206), Expect = 8e-17
Identities = 36/71 (50%), Positives = 51/71 (71%)
Frame = +1
Query: 295 KKSLRVAIIGQSTFAAEVFKLIQRDGHEVVGVFTIPDKGNREDPLATIAAQNGKPVYKYK 474
K L++A+IGQS F EV+ ++++GH VVGVFT+PDK + DPLA A ++G PV+K
Sbjct: 20 KNKLKLALIGQSLFGQEVYSHLRKEGHRVVGVFTVPDKDGKADPLALAAEKDGTPVFKLP 79
Query: 475 SWRIKGQVIPE 507
WR+KG+ I E
Sbjct: 80 KWRVKGKTIKE 90
Score = 45.6 bits (103), Expect = 2e-04
Identities = 17/27 (62%), Positives = 24/27 (88%)
Frame = +2
Query: 770 DDTVDTIYNKFLYPEGIKALAEAVNMV 850
+DTVD +YN+FL+PEGIKA+ EAV ++
Sbjct: 179 NDTVDALYNRFLFPEGIKAMVEAVQLI 205
>BC027241-1|AAH27241.1| 505|Homo sapiens ALDH1L1 protein protein.
Length = 505
Score = 136 bits (329), Expect = 1e-31
Identities = 57/79 (72%), Positives = 71/79 (89%)
Frame = +3
Query: 516 QYKSVNADLNVLPFCTQFIPMEVITAPKYESICYHPSILPRHRGASSVNWTLIEGDTTCG 695
+Y+++ A+LNVLPFC+QFIPME+I+AP++ SI YHPS+LPRHRGAS++NWTLI GD G
Sbjct: 72 KYQALGAELNVLPFCSQFIPMEIISAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGG 131
Query: 696 FSIFWADDGLDTGPILLQK 752
FSIFWADDGLDTG +LLQK
Sbjct: 132 FSIFWADDGLDTGDLLLQK 150
Score = 87.8 bits (208), Expect = 4e-17
Identities = 35/68 (51%), Positives = 51/68 (75%)
Frame = +1
Query: 304 LRVAIIGQSTFAAEVFKLIQRDGHEVVGVFTIPDKGNREDPLATIAAQNGKPVYKYKSWR 483
+++A+IGQS F EV+ ++++GHEVVGVFT+PDK + DPL A ++G PV+KY WR
Sbjct: 1 MKIAVIGQSLFGQEVYCHLRKEGHEVVGVFTVPDKDGKADPLGLEAEKDGVPVFKYSRWR 60
Query: 484 IKGQVIPE 507
KGQ +P+
Sbjct: 61 AKGQALPD 68
Score = 45.6 bits (103), Expect = 2e-04
Identities = 18/34 (52%), Positives = 25/34 (73%)
Frame = +2
Query: 749 KELSQTIDDTVDTIYNKFLYPEGIKALAEAVNMV 850
KE DDTV T+YN+FL+PEGIK + +AV ++
Sbjct: 150 KECEVLPDDTVSTLYNRFLFPEGIKGMVQAVRLI 183
>AK222694-1|BAD96414.1| 902|Homo sapiens formyltetrahydrofolate
dehydrogenase isoform a variant protein.
Length = 902
Score = 136 bits (329), Expect = 1e-31
Identities = 57/79 (72%), Positives = 71/79 (89%)
Frame = +3
Query: 516 QYKSVNADLNVLPFCTQFIPMEVITAPKYESICYHPSILPRHRGASSVNWTLIEGDTTCG 695
+Y+++ A+LNVLPFC+QFIPME+I+AP++ SI YHPS+LPRHRGAS++NWTLI GD G
Sbjct: 72 KYQALGAELNVLPFCSQFIPMEIISAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGG 131
Query: 696 FSIFWADDGLDTGPILLQK 752
FSIFWADDGLDTG +LLQK
Sbjct: 132 FSIFWADDGLDTGDLLLQK 150
Score = 87.8 bits (208), Expect = 4e-17
Identities = 35/68 (51%), Positives = 51/68 (75%)
Frame = +1
Query: 304 LRVAIIGQSTFAAEVFKLIQRDGHEVVGVFTIPDKGNREDPLATIAAQNGKPVYKYKSWR 483
+++A+IGQS F EV+ ++++GHEVVGVFT+PDK + DPL A ++G PV+KY WR
Sbjct: 1 MKIAVIGQSLFGQEVYCHLRKEGHEVVGVFTVPDKDGKADPLGLEAEKDGVPVFKYSRWR 60
Query: 484 IKGQVIPE 507
KGQ +P+
Sbjct: 61 AKGQALPD 68
Score = 45.6 bits (103), Expect = 2e-04
Identities = 18/34 (52%), Positives = 25/34 (73%)
Frame = +2
Query: 749 KELSQTIDDTVDTIYNKFLYPEGIKALAEAVNMV 850
KE DDTV T+YN+FL+PEGIK + +AV ++
Sbjct: 150 KECEVLPDDTVSTLYNRFLFPEGIKGMVQAVRLI 183
>AK222535-1|BAD96255.1| 902|Homo sapiens formyltetrahydrofolate
dehydrogenase isoform a variant protein.
Length = 902
Score = 136 bits (329), Expect = 1e-31
Identities = 57/79 (72%), Positives = 71/79 (89%)
Frame = +3
Query: 516 QYKSVNADLNVLPFCTQFIPMEVITAPKYESICYHPSILPRHRGASSVNWTLIEGDTTCG 695
+Y+++ A+LNVLPFC+QFIPME+I+AP++ SI YHPS+LPRHRGAS++NWTLI GD G
Sbjct: 72 KYQALGAELNVLPFCSQFIPMEIISAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGG 131
Query: 696 FSIFWADDGLDTGPILLQK 752
FSIFWADDGLDTG +LLQK
Sbjct: 132 FSIFWADDGLDTGDLLLQK 150
Score = 87.8 bits (208), Expect = 4e-17
Identities = 35/68 (51%), Positives = 51/68 (75%)
Frame = +1
Query: 304 LRVAIIGQSTFAAEVFKLIQRDGHEVVGVFTIPDKGNREDPLATIAAQNGKPVYKYKSWR 483
+++A+IGQS F EV+ ++++GHEVVGVFT+PDK + DPL A ++G PV+KY WR
Sbjct: 1 MKIAVIGQSLFGQEVYCHLRKEGHEVVGVFTVPDKDGKADPLGLEAEKDGVPVFKYSRWR 60
Query: 484 IKGQVIPE 507
KGQ +P+
Sbjct: 61 AKGQALPD 68
Score = 45.6 bits (103), Expect = 2e-04
Identities = 18/34 (52%), Positives = 25/34 (73%)
Frame = +2
Query: 749 KELSQTIDDTVDTIYNKFLYPEGIKALAEAVNMV 850
KE DDTV T+YN+FL+PEGIK + +AV ++
Sbjct: 150 KECEVLPDDTVSTLYNRFLFPEGIKGMVQAVRLI 183
>AB209299-1|BAD92536.1| 954|Homo sapiens aldehyde dehydrogenase 1
family, member L1 variant protein.
Length = 954
Score = 136 bits (329), Expect = 1e-31
Identities = 57/79 (72%), Positives = 71/79 (89%)
Frame = +3
Query: 516 QYKSVNADLNVLPFCTQFIPMEVITAPKYESICYHPSILPRHRGASSVNWTLIEGDTTCG 695
+Y+++ A+LNVLPFC+QFIPME+I+AP++ SI YHPS+LPRHRGAS++NWTLI GD G
Sbjct: 124 KYQALGAELNVLPFCSQFIPMEIISAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGG 183
Query: 696 FSIFWADDGLDTGPILLQK 752
FSIFWADDGLDTG +LLQK
Sbjct: 184 FSIFWADDGLDTGDLLLQK 202
Score = 90.2 bits (214), Expect = 8e-18
Identities = 36/72 (50%), Positives = 53/72 (73%)
Frame = +1
Query: 292 PKKSLRVAIIGQSTFAAEVFKLIQRDGHEVVGVFTIPDKGNREDPLATIAAQNGKPVYKY 471
P ++++A+IGQS F EV+ ++++GHEVVGVFT+PDK + DPL A ++G PV+KY
Sbjct: 49 PPATMKIAVIGQSLFGQEVYCHLRKEGHEVVGVFTVPDKDGKADPLGLEAEKDGVPVFKY 108
Query: 472 KSWRIKGQVIPE 507
WR KGQ +P+
Sbjct: 109 SRWRAKGQALPD 120
Score = 45.6 bits (103), Expect = 2e-04
Identities = 18/34 (52%), Positives = 25/34 (73%)
Frame = +2
Query: 749 KELSQTIDDTVDTIYNKFLYPEGIKALAEAVNMV 850
KE DDTV T+YN+FL+PEGIK + +AV ++
Sbjct: 202 KECEVLPDDTVSTLYNRFLFPEGIKGMVQAVRLI 235
>AF052732-1|AAC35000.1| 902|Homo sapiens 10-formyltetrahydrofolate
dehydrogenase protein.
Length = 902
Score = 133 bits (321), Expect = 9e-31
Identities = 56/79 (70%), Positives = 70/79 (88%)
Frame = +3
Query: 516 QYKSVNADLNVLPFCTQFIPMEVITAPKYESICYHPSILPRHRGASSVNWTLIEGDTTCG 695
+Y+++ A+LNVLP C+QFIPME+I+AP++ SI YHPS+LPRHRGAS++NWTLI GD G
Sbjct: 72 KYQALGAELNVLPSCSQFIPMEIISAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGG 131
Query: 696 FSIFWADDGLDTGPILLQK 752
FSIFWADDGLDTG +LLQK
Sbjct: 132 FSIFWADDGLDTGDLLLQK 150
Score = 85.4 bits (202), Expect = 2e-16
Identities = 34/68 (50%), Positives = 50/68 (73%)
Frame = +1
Query: 304 LRVAIIGQSTFAAEVFKLIQRDGHEVVGVFTIPDKGNREDPLATIAAQNGKPVYKYKSWR 483
+++A+IGQS F EV+ ++++GHEVVGVFT+PDK + DPL A ++G PV+KY WR
Sbjct: 1 MKIAVIGQSLFGQEVYCHLRKEGHEVVGVFTVPDKDGKADPLGLEAEKDGVPVFKYSRWR 60
Query: 484 IKGQVIPE 507
K Q +P+
Sbjct: 61 AKAQALPD 68
Score = 45.2 bits (102), Expect = 3e-04
Identities = 18/34 (52%), Positives = 25/34 (73%)
Frame = +2
Query: 749 KELSQTIDDTVDTIYNKFLYPEGIKALAEAVNMV 850
KE DDTV T+YN+FL+PEGIK + +AV ++
Sbjct: 150 KECEVLPDDTVSTLYNRFLFPEGIKGVVQAVRLI 183
>AL133015-1|CAB61356.1| 240|Homo sapiens hypothetical protein
protein.
Length = 240
Score = 100 bits (239), Expect = 8e-21
Identities = 42/57 (73%), Positives = 50/57 (87%)
Frame = +3
Query: 582 VITAPKYESICYHPSILPRHRGASSVNWTLIEGDTTCGFSIFWADDGLDTGPILLQK 752
+I+AP++ SI YHPS+LPRHRGAS++NWTLI GD GFSIFWADDGLDTG +LLQK
Sbjct: 1 IISAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFSIFWADDGLDTGDLLLQK 57
Score = 41.1 bits (92), Expect = 0.005
Identities = 17/28 (60%), Positives = 21/28 (75%)
Frame = +2
Query: 749 KELSQTIDDTVDTIYNKFLYPEGIKALA 832
KE DDTV T+YN+FL+PEGIK +A
Sbjct: 57 KECEVLPDDTVSTLYNRFLFPEGIKGMA 84
>BC033687-1|AAH33687.1| 304|Homo sapiens mitochondrial
methionyl-tRNA formyltransferase protein.
Length = 304
Score = 45.2 bits (102), Expect = 3e-04
Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Frame = +3
Query: 537 DLNVLPFCTQFIPMEVITAPKYESICYHPSILPRHRGASSVNWTLIEGDTTCGFSIFW-A 713
D+ V+ + + +I Y + HPS LPR RG + V T++ GDT G +I
Sbjct: 34 DVGVVASFGRLLNEALILKFPYGILNVHPSCLPRWRGPAPVIHTVLHGDTVTGVTIMQIR 93
Query: 714 DDGLDTGPILLQKSYPKP 767
D GPIL Q++ P P
Sbjct: 94 PKRFDVGPILKQETVPVP 111
>BC016630-1|AAH16630.2| 304|Homo sapiens mitochondrial
methionyl-tRNA formyltransferase protein.
Length = 304
Score = 45.2 bits (102), Expect = 3e-04
Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Frame = +3
Query: 537 DLNVLPFCTQFIPMEVITAPKYESICYHPSILPRHRGASSVNWTLIEGDTTCGFSIFW-A 713
D+ V+ + + +I Y + HPS LPR RG + V T++ GDT G +I
Sbjct: 34 DVGVVASFGRLLNEALILKFPYGILNVHPSCLPRWRGPAPVIHTVLHGDTVTGVTIMQIR 93
Query: 714 DDGLDTGPILLQKSYPKP 767
D GPIL Q++ P P
Sbjct: 94 PKRFDVGPILKQETVPVP 111
>AK055688-1|BAB70984.1| 304|Homo sapiens protein ( Homo sapiens
cDNA FLJ31126 fis, clone IMR322000838, highly similar to
METHIONYL-TRNA FORMYLTRANSFERASE, MITOCHONDRIAL
PRECURSOR (EC ).
Length = 304
Score = 45.2 bits (102), Expect = 3e-04
Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Frame = +3
Query: 537 DLNVLPFCTQFIPMEVITAPKYESICYHPSILPRHRGASSVNWTLIEGDTTCGFSIFW-A 713
D+ V+ + + +I Y + HPS LPR RG + V T++ GDT G +I
Sbjct: 34 DVGVVASFGRLLNEALILKFPYGILNVHPSCLPRWRGPAPVIHTVLHGDTVTGVTIMQIR 93
Query: 714 DDGLDTGPILLQKSYPKP 767
D GPIL Q++ P P
Sbjct: 94 PKRFDVGPILKQETVPVP 111
>X54199-1|CAA38119.1| 1010|Homo sapiens glycinamide ribonucleotide
synthetase-aminoimidazole ribonucleotide synthetase-
protein.
Length = 1010
Score = 38.3 bits (85), Expect = 0.035
Identities = 16/48 (33%), Positives = 29/48 (60%)
Frame = +3
Query: 618 HPSILPRHRGASSVNWTLIEGDTTCGFSIFWADDGLDTGPILLQKSYP 761
HPS+LP +G+++ L G T G ++ + + +D G I+LQ++ P
Sbjct: 915 HPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEAVP 962
>M32082-1|AAA60077.1| 302|Homo sapiens GART protein.
Length = 302
Score = 38.3 bits (85), Expect = 0.035
Identities = 16/48 (33%), Positives = 29/48 (60%)
Frame = +3
Query: 618 HPSILPRHRGASSVNWTLIEGDTTCGFSIFWADDGLDTGPILLQKSYP 761
HPS+LP +G+++ L G T G ++ + + +D G I+LQ++ P
Sbjct: 207 HPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEAVP 254
>BC107712-1|AAI07713.1| 1010|Homo sapiens phosphoribosylglycinamide
formyltransferase, phosphoribosylglycinamide syntheta
protein.
Length = 1010
Score = 38.3 bits (85), Expect = 0.035
Identities = 16/48 (33%), Positives = 29/48 (60%)
Frame = +3
Query: 618 HPSILPRHRGASSVNWTLIEGDTTCGFSIFWADDGLDTGPILLQKSYP 761
HPS+LP +G+++ L G T G ++ + + +D G I+LQ++ P
Sbjct: 915 HPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEAVP 962
>AB208785-1|BAD92022.1| 1046|Homo sapiens phosphoribosylglycinamide
formyltransferase, phosphoribosylglycinamide syntheta
protein.
Length = 1046
Score = 38.3 bits (85), Expect = 0.035
Identities = 16/48 (33%), Positives = 29/48 (60%)
Frame = +3
Query: 618 HPSILPRHRGASSVNWTLIEGDTTCGFSIFWADDGLDTGPILLQKSYP 761
HPS+LP +G+++ L G T G ++ + + +D G I+LQ++ P
Sbjct: 951 HPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEAVP 998
>Z19585-1|CAA79635.1| 961|Homo sapiens thrombospondin-4 protein.
Length = 961
Score = 30.3 bits (65), Expect = 9.3
Identities = 18/55 (32%), Positives = 24/55 (43%)
Frame = +3
Query: 597 KYESICYHPSILPRHRGASSVNWTLIEGDTTCGFSIFWADDGLDTGPILLQKSYP 761
K E C +P + P A + +GD TC + WA DG G + SYP
Sbjct: 419 KVERNCRNPELNPCSVNAQCIEER--QGDVTCVCGVGWAGDGYICGKDVDIDSYP 471
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 126,693,439
Number of Sequences: 237096
Number of extensions: 2804530
Number of successful extensions: 4104
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 3925
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4096
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10816958492
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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