Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= e40h0809
(726 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q4SRH5 Cluster: L-lactate dehydrogenase; n=4; Euteleost... 126 7e-28
UniRef50_UPI0000519EC7 Cluster: PREDICTED: similar to Ecdysone-i... 111 2e-23
UniRef50_P07864 Cluster: L-lactate dehydrogenase C chain; n=371;... 108 1e-22
UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12; Bacteria... 105 1e-21
UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12; Firmic... 103 6e-21
UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11; Clostrid... 101 1e-20
UniRef50_P22988 Cluster: L-lactate dehydrogenase A; n=19; Magnol... 101 2e-20
UniRef50_Q1IRL5 Cluster: L-lactate dehydrogenase; n=6; Bacteria|... 100 4e-20
UniRef50_P20619 Cluster: L-lactate dehydrogenase X; n=14; Bacill... 95 2e-18
UniRef50_Q7NG49 Cluster: L-lactate dehydrogenase; n=4; Cyanobact... 93 8e-18
UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9; Bacilli... 89 8e-17
UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula... 89 1e-16
UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140; Bacteri... 88 2e-16
UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2; ... 88 2e-16
UniRef50_A6NLX8 Cluster: L-lactate dehydrogenase; n=4; Eutheria|... 86 1e-15
UniRef50_Q4JY42 Cluster: L-lactate dehydrogenase; n=1; Corynebac... 86 1e-15
UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia ... 86 1e-15
UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibac... 85 1e-15
UniRef50_Q8IX04 Cluster: Ubiquitin-conjugating enzyme E2 variant... 85 2e-15
UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17; Bacter... 85 2e-15
UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4; Lactobaci... 85 2e-15
UniRef50_A4QXM2 Cluster: Putative uncharacterized protein; n=1; ... 84 4e-15
UniRef50_UPI0000DB7268 Cluster: PREDICTED: similar to L-lactate ... 82 1e-14
UniRef50_A5KJY5 Cluster: Putative uncharacterized protein; n=2; ... 82 2e-14
UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;... 82 2e-14
UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1; Lept... 81 2e-14
UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2; Euryarchaeot... 81 3e-14
UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8; Lactoba... 81 3e-14
UniRef50_Q81XJ7 Cluster: L-lactate dehydrogenase 3; n=13; Firmic... 80 6e-14
UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28; Bacteroidet... 79 8e-14
UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7; Bacteria|... 79 8e-14
UniRef50_Q8ELF0 Cluster: L-lactate dehydrogenase; n=5; Bacillace... 79 1e-13
UniRef50_Q3U1V6 Cluster: Ubiquitin-conjugating enzyme E2 variant... 77 3e-13
UniRef50_A1U9V0 Cluster: Lactate/malate dehydrogenase; n=6; Acti... 77 6e-13
UniRef50_Q6NPB9 Cluster: AT22132p; n=2; Drosophila melanogaster|... 76 1e-12
UniRef50_A6M0Q2 Cluster: L-lactate dehydrogenase; n=1; Clostridi... 75 1e-12
UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4; Thermotog... 75 1e-12
UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=... 74 3e-12
UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4; Thermoplasma... 74 3e-12
UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|R... 73 5e-12
UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2; Propionib... 73 5e-12
UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2; Desulfovi... 73 5e-12
UniRef50_Q4L941 Cluster: L-lactate dehydrogenase; n=1; Staphyloc... 73 1e-11
UniRef50_Q8RED8 Cluster: L-lactate dehydrogenase; n=3; Fusobacte... 73 1e-11
UniRef50_UPI00015B6427 Cluster: PREDICTED: similar to lactate de... 72 1e-11
UniRef50_Q185V1 Cluster: L-lactate dehydrogenase; n=3; Clostridi... 71 2e-11
UniRef50_Q0UX88 Cluster: L-lactate dehydrogenase; n=2; Phaeospha... 71 2e-11
UniRef50_A1C5Q5 Cluster: L-lactate dehydrogenase; n=4; Pezizomyc... 71 3e-11
UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizop... 71 3e-11
UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1; Ther... 71 4e-11
UniRef50_Q92BI0 Cluster: L-lactate dehydrogenase 2; n=18; Bacter... 71 4e-11
UniRef50_A0RPE9 Cluster: Malate dehydrogenase; n=1; Campylobacte... 70 5e-11
UniRef50_Q5B0T8 Cluster: Putative uncharacterized protein; n=1; ... 70 5e-11
UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobu... 70 5e-11
UniRef50_P62056 Cluster: L-lactate dehydrogenase; n=2; Bacteria|... 70 7e-11
UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular org... 69 9e-11
UniRef50_P47698 Cluster: L-lactate dehydrogenase; n=2; Mycoplasm... 69 1e-10
UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Re... 69 2e-10
UniRef50_UPI0000DB7267 Cluster: PREDICTED: similar to Ecdysone-i... 68 2e-10
UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=... 67 4e-10
UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3; Acti... 67 4e-10
UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3; Methanomi... 67 4e-10
UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex ae... 67 4e-10
UniRef50_Q9CGG8 Cluster: L-lactate dehydrogenase 3; n=3; Lactoco... 67 4e-10
UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2; Pl... 67 5e-10
UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1; Cand... 66 6e-10
UniRef50_Q6YPG1 Cluster: Putative uncharacterized protein OJA121... 66 8e-10
UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;... 66 1e-09
UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14; Thermoprote... 66 1e-09
UniRef50_A7I2F1 Cluster: Malate dehydrogenase; n=1; Campylobacte... 65 2e-09
UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4; Bacteria|... 64 3e-09
UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD bindi... 64 4e-09
UniRef50_A3ZZ88 Cluster: L-lactate/malate dehydrogenase; n=1; Bl... 64 4e-09
UniRef50_A7DSJ4 Cluster: Lactate/malate dehydrogenase; n=1; Cand... 63 6e-09
UniRef50_P59050 Cluster: L-lactate dehydrogenase 1; n=3; Bifidob... 63 6e-09
UniRef50_UPI000038D9FF Cluster: COG0039: Malate/lactate dehydrog... 63 8e-09
UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1; Ce... 62 1e-08
UniRef50_UPI000023CE12 Cluster: hypothetical protein FG10444.1; ... 62 2e-08
UniRef50_A4BB89 Cluster: Lactate dehydrogenase; n=2; Gammaproteo... 62 2e-08
UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6; Mollicute... 62 2e-08
UniRef50_Q97DC6 Cluster: L-lactate dehydrogenase 2; n=1; Clostri... 62 2e-08
UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 61 2e-08
UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1; Lactobaci... 61 3e-08
UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular or... 60 5e-08
UniRef50_Q0PQR8 Cluster: Malate dehydrogenase NAD-dependent; n=1... 60 7e-08
UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2;... 60 7e-08
UniRef50_Q2FPC3 Cluster: Lactate/malate dehydrogenase; n=2; Meth... 60 7e-08
UniRef50_O26290 Cluster: Malate dehydrogenase; n=2; Methanobacte... 59 1e-07
UniRef50_Q4A0K7 Cluster: Lactate dehydrogenase; n=1; Staphylococ... 59 1e-07
UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 59 1e-07
UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;... 58 2e-07
UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5; Gammaproteob... 58 2e-07
UniRef50_A2UB98 Cluster: Lactate/malate dehydrogenase precursor;... 58 3e-07
UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1; ... 57 4e-07
UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2... 57 4e-07
UniRef50_Q6LZI3 Cluster: Malate dehydrogenase; n=5; Methanococcu... 57 4e-07
UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7; Halobacteria... 57 5e-07
UniRef50_Q87JV1 Cluster: Lactate dehydrogenase; n=4; Vibrio|Rep:... 56 7e-07
UniRef50_Q0P989 Cluster: L-lactate dehydrogenase; n=10; Campylob... 56 7e-07
UniRef50_Q9EVR0 Cluster: L-lactate dehydrogenase; n=1; Selenomon... 56 1e-06
UniRef50_Q03ZZ4 Cluster: Enzyme with possible activities of L-2-... 55 2e-06
UniRef50_A2QJT7 Cluster: Catalytic activity: precursor; n=1; Asp... 55 2e-06
UniRef50_Q27743 Cluster: L-lactate dehydrogenase; n=17; Apicompl... 55 2e-06
UniRef50_Q6JH30 Cluster: Lactate dehydrogenase; n=3; Plasmodium ... 55 2e-06
UniRef50_Q8I8U4 Cluster: Lactate dehydrogenase; n=3; Eimeriorina... 54 3e-06
UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular o... 54 3e-06
UniRef50_Q9PHY2 Cluster: Probable malate dehydrogenase; n=12; Ca... 54 3e-06
UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like prot... 53 8e-06
UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter... 53 8e-06
UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;... 52 2e-05
UniRef50_Q6ABQ3 Cluster: L-lactate dehydrogenase; n=1; Propionib... 52 2e-05
UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasm... 52 2e-05
UniRef50_Q92AZ3 Cluster: Lin1775 protein; n=13; Listeria|Rep: Li... 51 3e-05
UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4; Epsilonprote... 51 3e-05
UniRef50_Q5CYZ2 Cluster: Lactate dehydrogenase, adjacent gene en... 51 3e-05
UniRef50_A3CTN0 Cluster: Lactate/malate dehydrogenase; n=1; Meth... 51 3e-05
UniRef50_P14295 Cluster: L-2-hydroxyisocaproate dehydrogenase; n... 50 6e-05
UniRef50_Q88ZG9 Cluster: L-2-hydroxyisocaproate dehydrogenase; n... 50 8e-05
UniRef50_Q04GC4 Cluster: Enzyme with possible activities of L-2-... 49 1e-04
UniRef50_Q5M0L6 Cluster: L-2-hydroxyisocaproate dehydrogenase; n... 48 2e-04
UniRef50_O52354 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 48 3e-04
UniRef50_A4E9T4 Cluster: Putative uncharacterized protein; n=1; ... 47 5e-04
UniRef50_Q6A6E3 Cluster: L-lactate dehydrogenase; n=1; Propionib... 46 7e-04
UniRef50_Q8IE66 Cluster: Oxidoreductase, putative; n=6; Plasmodi... 46 7e-04
UniRef50_Q38YI2 Cluster: Putative malate dehydrogenase; n=1; Lac... 46 0.001
UniRef50_Q82R06 Cluster: Putative lactate dehydrogenase; n=1; St... 45 0.002
UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|R... 45 0.002
UniRef50_A5IYS9 Cluster: L-lactate dehydrogenase; n=2; Mycoplasm... 42 0.012
UniRef50_Q034P5 Cluster: Enzyme with possible activities of L-2-... 42 0.021
UniRef50_A2SR33 Cluster: Lactate/malate dehydrogenase; n=1; Meth... 42 0.021
UniRef50_Q5FIY9 Cluster: L-LDH; n=6; Lactobacillus|Rep: L-LDH - ... 40 0.047
UniRef50_Q1FMY2 Cluster: L-lactate dehydrogenase; n=1; Clostridi... 39 0.11
UniRef50_Q091H7 Cluster: Oxidoreductase; n=2; Myxococcales|Rep: ... 37 0.44
UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;... 37 0.58
UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa ... 36 0.77
UniRef50_Q4RTQ4 Cluster: Chromosome 2 SCAF14997, whole genome sh... 35 2.4
UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4; Bacteroidale... 34 3.1
UniRef50_Q02D27 Cluster: Oxidoreductase domain protein; n=1; Sol... 34 3.1
UniRef50_A0QSN0 Cluster: Ftsk/spoiiie family protein; n=1; Mycob... 34 3.1
UniRef50_A2YRW8 Cluster: Putative uncharacterized protein; n=2; ... 34 3.1
UniRef50_Q0UTY3 Cluster: Putative uncharacterized protein; n=1; ... 34 3.1
UniRef50_Q6NYY8 Cluster: Smox protein; n=12; Coelomata|Rep: Smox... 34 4.1
UniRef50_Q8EYH1 Cluster: Methyl-accepting chemotaxis protein; n=... 34 4.1
UniRef50_Q1U8H4 Cluster: L-lactate dehydrogenase; n=2; Lactobaci... 33 5.4
UniRef50_Q15ST6 Cluster: UBA/THIF-type NAD/FAD binding fold; n=2... 33 5.4
UniRef50_A0UYP0 Cluster: Amine oxidase; n=1; Clostridium cellulo... 33 5.4
UniRef50_Q8IMQ3 Cluster: CG31077-PA; n=1; Drosophila melanogaste... 33 5.4
UniRef50_UPI00015C41A2 Cluster: hypothetical protein SGO_0439; n... 33 7.2
UniRef50_Q1MTF8 Cluster: Novel protein; n=4; Danio rerio|Rep: No... 33 7.2
UniRef50_Q1D1Z7 Cluster: Putative uncharacterized protein; n=1; ... 33 7.2
UniRef50_A1T9V4 Cluster: FAD dependent oxidoreductase; n=1; Myco... 33 7.2
UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=... 33 7.2
UniRef50_Q6ANF8 Cluster: Related to dipeptidase; n=17; Bacteria|... 33 9.5
UniRef50_Q5H1J1 Cluster: Glyoxylase I family protein; n=2; Xanth... 33 9.5
UniRef50_Q577J1 Cluster: Alcohol dehydrogenase, zinc-containing;... 33 9.5
UniRef50_A1TDB4 Cluster: Amine oxidase precursor; n=2; Mycobacte... 33 9.5
UniRef50_Q6ZCA3 Cluster: Putative uncharacterized protein P0547A... 33 9.5
UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1; ... 33 9.5
>UniRef50_Q4SRH5 Cluster: L-lactate dehydrogenase; n=4;
Euteleostomi|Rep: L-lactate dehydrogenase - Tetraodon
nigroviridis (Green puffer)
Length = 360
Score = 126 bits (303), Expect = 7e-28
Identities = 55/72 (76%), Positives = 66/72 (91%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SRL+LVQRN +V K IIPQ+IKYSP+ L++ SNPVD+LTYVTWK+SGLPKHRVIGSGTN
Sbjct: 106 SRLNLVQRNVNVFKSIIPQIIKYSPNCTLIVVSNPVDVLTYVTWKLSGLPKHRVIGSGTN 165
Query: 690 LDSARFRYLLSD 725
LDSARFRYL+++
Sbjct: 166 LDSARFRYLMAE 177
Score = 114 bits (275), Expect = 2e-24
Identities = 51/84 (60%), Positives = 71/84 (84%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 438
+KVT+VGVGQVGMA A S+L +++ + +ALVD+M D+LKGE+MDLQHGS F++ +KI +
Sbjct: 22 NKVTVVGVGQVGMACAISILLRDLADELALVDVMEDRLKGELMDLQHGSLFLKTSKIVAD 81
Query: 439 TDYSITAGSKICVVTAGVRQREGD 510
DYS+TA S++ VVTAGVRQ+EG+
Sbjct: 82 KDYSVTANSRLVVVTAGVRQQEGE 105
>UniRef50_UPI0000519EC7 Cluster: PREDICTED: similar to
Ecdysone-inducible gene L3 CG10160-PA; n=2;
Apocrita|Rep: PREDICTED: similar to Ecdysone-inducible
gene L3 CG10160-PA - Apis mellifera
Length = 409
Score = 111 bits (267), Expect = 2e-23
Identities = 47/72 (65%), Positives = 65/72 (90%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SRLDLVQRN+++LK IIP L+ YSP+ ++++ SNPVDIL+++TWKISGLP RVIG+GT+
Sbjct: 181 SRLDLVQRNSEILKSIIPTLVGYSPNAVILVVSNPVDILSWLTWKISGLPASRVIGTGTH 240
Query: 690 LDSARFRYLLSD 725
+DSARFR+L++D
Sbjct: 241 VDSARFRFLIAD 252
Score = 77.8 bits (183), Expect = 3e-13
Identities = 35/83 (42%), Positives = 55/83 (66%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 441
KVT+VG G VG+A +++ Q +T ++A+VD KL+GE MD HG + + + +I T
Sbjct: 98 KVTVVGSGMVGVAIVNALIFQKITAHVAMVDAFPKKLEGEGMDYCHGLSLIESPRIDFDT 157
Query: 442 DYSITAGSKICVVTAGVRQREGD 510
D+ IT+ SK+ V+ AG RQ +G+
Sbjct: 158 DFCITSNSKVIVLAAGARQMKGE 180
>UniRef50_P07864 Cluster: L-lactate dehydrogenase C chain; n=371;
Eukaryota|Rep: L-lactate dehydrogenase C chain - Homo
sapiens (Human)
Length = 332
Score = 108 bits (260), Expect = 1e-22
Identities = 51/101 (50%), Positives = 70/101 (69%)
Frame = +1
Query: 208 VPEEAVPARAREGGRNWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMM 387
V E+ + + + K+TIVG G VGMA A S+L +++ + +ALVD+ DKLKGEMM
Sbjct: 4 VKEQLIEKLIEDDENSQCKITIVGTGAVGMACAISILLKDLADELALVDVALDKLKGEMM 63
Query: 388 DLQHGSAFMRNAKIQSSTDYSITAGSKICVVTAGVRQREGD 510
DLQHGS F +KI S DYS++A S+I +VTAG RQ+EG+
Sbjct: 64 DLQHGSLFFSTSKITSGKDYSVSANSRIVIVTAGARQQEGE 104
Score = 106 bits (254), Expect = 6e-22
Identities = 47/72 (65%), Positives = 58/72 (80%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RL LVQRN ++K IIP ++ YSPD +++ SNPVDILTY+ WKISGLP RVIGSG N
Sbjct: 105 TRLALVQRNVAIMKSIIPAIVHYSPDCKILVVSNPVDILTYIVWKISGLPVTRVIGSGCN 164
Query: 690 LDSARFRYLLSD 725
LDSARFRYL+ +
Sbjct: 165 LDSARFRYLIGE 176
>UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12;
Bacteria|Rep: L-lactate dehydrogenase - Clostridium
tetani
Length = 316
Score = 105 bits (251), Expect = 1e-21
Identities = 44/72 (61%), Positives = 62/72 (86%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RLDL+ +N ++ K I+P+++KYSP +IL++ SNPVDILTYVT+K+SG P+ RVIGSGT
Sbjct: 89 TRLDLINKNYEIFKGIVPEVVKYSPKSILLVVSNPVDILTYVTYKLSGFPQERVIGSGTV 148
Query: 690 LDSARFRYLLSD 725
LD++RFRYLL +
Sbjct: 149 LDTSRFRYLLGE 160
Score = 65.7 bits (153), Expect = 1e-09
Identities = 30/83 (36%), Positives = 51/83 (61%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 441
K++I+G G VG A++++ + + + I +VD+ +K KGE MDL HG +F++ I +
Sbjct: 7 KISIIGSGFVGSTTAYALMMEGLASEIVIVDINKEKAKGEAMDLSHGVSFVKPVDIIAG- 65
Query: 442 DYSITAGSKICVVTAGVRQREGD 510
DY T S I ++TAG + G+
Sbjct: 66 DYEDTKDSDIVIITAGAGPKPGE 88
>UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12;
Firmicutes|Rep: L-lactate dehydrogenase 2 - Bacillus
anthracis
Length = 314
Score = 103 bits (246), Expect = 6e-21
Identities = 48/72 (66%), Positives = 58/72 (80%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RLDLV++NT + KQI+ ++ D I +IA+NPVDILTYVTWK SGLPK RVIGSGT
Sbjct: 90 TRLDLVEKNTKIFKQIVRGIMDSGFDGIFLIATNPVDILTYVTWKESGLPKERVIGSGTT 149
Query: 690 LDSARFRYLLSD 725
LDSARFRY+L D
Sbjct: 150 LDSARFRYMLGD 161
Score = 59.7 bits (138), Expect = 7e-08
Identities = 30/84 (35%), Positives = 46/84 (54%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 438
++V +VG G VG + A+SM+ Q V LVD+ K +GE MDL H F + S
Sbjct: 6 NRVVLVGTGAVGCSYAYSMINQGVAEEFVLVDVNEAKAEGEAMDLSHAVPFSPSPTKVWS 65
Query: 439 TDYSITAGSKICVVTAGVRQREGD 510
Y+ + + V+TAG+ Q+ G+
Sbjct: 66 GSYADCKDADLVVITAGLPQKPGE 89
>UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11;
Clostridium|Rep: L-lactate dehydrogenase - Clostridium
perfringens
Length = 317
Score = 101 bits (243), Expect = 1e-20
Identities = 40/72 (55%), Positives = 62/72 (86%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RLD++ +N + + I+P+++KYSP++IL++ SNPVDILTY+T+K+SG PK RVIGSGT
Sbjct: 90 TRLDIINKNLKIFQSIVPEVVKYSPNSILLVVSNPVDILTYITYKLSGFPKERVIGSGTV 149
Query: 690 LDSARFRYLLSD 725
LD++R +Y+LS+
Sbjct: 150 LDTSRLKYMLSE 161
Score = 68.9 bits (161), Expect = 1e-10
Identities = 32/84 (38%), Positives = 53/84 (63%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 438
+K++I+G G VG AF+++ + + I +VD+ DK E MDL G+AF+++ I+S
Sbjct: 7 NKISIIGAGFVGSTTAFALMQDGLASEIVIVDINKDKAHAEAMDLAQGAAFVKSVDIKSG 66
Query: 439 TDYSITAGSKICVVTAGVRQREGD 510
DY+ T S I ++TAGV + G+
Sbjct: 67 -DYADTKDSDIVIITAGVGPKPGE 89
>UniRef50_P22988 Cluster: L-lactate dehydrogenase A; n=19;
Magnoliophyta|Rep: L-lactate dehydrogenase A - Hordeum
vulgare (Barley)
Length = 356
Score = 101 bits (242), Expect = 2e-20
Identities = 41/72 (56%), Positives = 61/72 (84%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RL+L+QRN + ++I+P + ++SPD +L++ SNPVD+LTYV WK+SG P RVIGSGTN
Sbjct: 127 TRLNLLQRNVALYRKIVPPVAEHSPDALLLVVSNPVDVLTYVAWKLSGFPASRVIGSGTN 186
Query: 690 LDSARFRYLLSD 725
LDS+RFR+L+++
Sbjct: 187 LDSSRFRFLIAE 198
Score = 94.3 bits (224), Expect = 3e-18
Identities = 47/103 (45%), Positives = 68/103 (66%)
Frame = +1
Query: 202 DGVPEEAVPARAREGGRNWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGE 381
DG P A P + R +K++++G G VGMA A ++LTQN+ + IALVD + DKL+GE
Sbjct: 27 DGCP--ATPTSSAVPHRRLTKISVIGAGNVGMAIAQTILTQNLADEIALVDALPDKLRGE 84
Query: 382 MMDLQHGSAFMRNAKIQSSTDYSITAGSKICVVTAGVRQREGD 510
+DLQH +AF+ +I S TD ++T S + +VTAG RQ G+
Sbjct: 85 ALDLQHAAAFLPRVRI-SGTDAAVTKNSDLVIVTAGARQIPGE 126
>UniRef50_Q1IRL5 Cluster: L-lactate dehydrogenase; n=6;
Bacteria|Rep: L-lactate dehydrogenase - Acidobacteria
bacterium (strain Ellin345)
Length = 321
Score = 100 bits (239), Expect = 4e-20
Identities = 42/70 (60%), Positives = 61/70 (87%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RL L+ RN + +QI+P+++K++PD +L+IA+NPVDI++Y ++KISGLP HRV+GSGT
Sbjct: 94 TRLQLLDRNLAIFQQIVPEVVKHNPDGLLLIATNPVDIISYASYKISGLPAHRVLGSGTI 153
Query: 690 LDSARFRYLL 719
LD+ARFRYLL
Sbjct: 154 LDTARFRYLL 163
Score = 60.5 bits (140), Expect = 4e-08
Identities = 29/83 (34%), Positives = 48/83 (57%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 441
++ +VG+G VG + AF++L + + I L+D K +GE MDL H F +I +
Sbjct: 12 RIAVVGLGNVGASFAFALLQRRLAAEIVLIDANHKKAEGEAMDLNHAVPFGAATRIWAG- 70
Query: 442 DYSITAGSKICVVTAGVRQREGD 510
+Y+ G+ + V+TAG QR G+
Sbjct: 71 EYADCRGAAVTVITAGAAQRPGE 93
>UniRef50_P20619 Cluster: L-lactate dehydrogenase X; n=14;
Bacillales|Rep: L-lactate dehydrogenase X - Bacillus
psychrosaccharolyticus
Length = 319
Score = 95.1 bits (226), Expect = 2e-18
Identities = 43/72 (59%), Positives = 55/72 (76%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RLDLV++N + K ++ Q++ D I +IA+NPVDILTY TWK SGLPK RVIGSGT
Sbjct: 91 TRLDLVEKNLKIFKSLVDQVMASGFDGIFLIATNPVDILTYATWKFSGLPKERVIGSGTI 150
Query: 690 LDSARFRYLLSD 725
LDS RFR+LL +
Sbjct: 151 LDSGRFRFLLGE 162
Score = 64.9 bits (151), Expect = 2e-09
Identities = 29/87 (33%), Positives = 48/87 (55%)
Frame = +1
Query: 250 RNWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKI 429
RN ++V ++G G VG + AF++L Q++T + ++D+ DK G+ MDL HG F N
Sbjct: 4 RNINRVALIGAGSVGSSYAFALLNQSITEELVIIDVNEDKAMGDAMDLNHGKIFAPNPTK 63
Query: 430 QSSTDYSITAGSKICVVTAGVRQREGD 510
+Y + I + AG Q+ G+
Sbjct: 64 TWYGNYDDCKEADIVCICAGANQKPGE 90
>UniRef50_Q7NG49 Cluster: L-lactate dehydrogenase; n=4;
Cyanobacteria|Rep: L-lactate dehydrogenase - Gloeobacter
violaceus
Length = 330
Score = 92.7 bits (220), Expect = 8e-18
Identities = 39/72 (54%), Positives = 59/72 (81%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RL LVQRN ++ + +I +++++ P+ IL++ SNPVD++TYV K++GLP RVIGSGT
Sbjct: 104 TRLSLVQRNVEIFRGLIGEIMEHCPNAILLVVSNPVDVMTYVAMKLAGLPPSRVIGSGTV 163
Query: 690 LDSARFRYLLSD 725
LD+ARFRYLL++
Sbjct: 164 LDTARFRYLLAE 175
Score = 74.9 bits (176), Expect = 2e-12
Identities = 41/96 (42%), Positives = 60/96 (62%), Gaps = 1/96 (1%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 441
K IVG G VGMA A+SML QN + + LVD+ K++GE+MDL HG F+ + +++ T
Sbjct: 22 KGAIVGAGAVGMAIAYSMLIQNTFDELVLVDIDRRKVEGEVMDLVHGIPFVEPSVVRAGT 81
Query: 442 DYSITAGSKICVVTAGVRQREGDL-VSISCRETPMF 546
+ G + V+TAG RQREG+ +S+ R +F
Sbjct: 82 -LADCRGVDVVVITAGARQREGETRLSLVQRNVEIF 116
>UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9;
Bacilli|Rep: L-lactate dehydrogenase 2 - Enterococcus
faecalis (Streptococcus faecalis)
Length = 317
Score = 89.4 bits (212), Expect = 8e-17
Identities = 43/71 (60%), Positives = 53/71 (74%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SRLDLV N +++K I+ ++K D ILVIASNPVD+LTYV W+ SGLP RVIG+GT
Sbjct: 90 SRLDLVSINAEIMKTIVNNIMKSGFDGILVIASNPVDVLTYVAWQASGLPVSRVIGTGTT 149
Query: 690 LDSARFRYLLS 722
LD+ RFR LS
Sbjct: 150 LDTTRFRKELS 160
Score = 61.3 bits (142), Expect = 2e-08
Identities = 38/107 (35%), Positives = 57/107 (53%), Gaps = 5/107 (4%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAF-MRNAKIQSS 438
KV I+G G VG + A+SM+ Q + N + LVD+ K +GE +DL G ++ N + +
Sbjct: 7 KVAIIGTGFVGTSIAYSMINQGIANELILVDIDKAKSEGEAIDLLDGVSWGQENVNVWAG 66
Query: 439 TDYSITAGSKICVVTAGVRQREG----DLVSISCRETPMFLNK*SRS 567
DY + I V+TAG Q+ G DLVSI+ +N +S
Sbjct: 67 -DYQDCQDADIVVITAGANQKPGQSRLDLVSINAEIMKTIVNNIMKS 112
>UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula
stellata E-37|Rep: L-lactate dehydrogenase - Sagittula
stellata E-37
Length = 300
Score = 89.0 bits (211), Expect = 1e-16
Identities = 41/70 (58%), Positives = 56/70 (80%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SRL+L+ RN +V + ++ + + +PD IL+IASNPVDI+T+VT +SGLP RVIGSGT
Sbjct: 75 SRLELLSRNAEVFRAVVGDVTRAAPDAILLIASNPVDIMTHVTQALSGLPAGRVIGSGTI 134
Query: 690 LDSARFRYLL 719
LD+ARFR+LL
Sbjct: 135 LDTARFRWLL 144
Score = 46.0 bits (104), Expect = 0.001
Identities = 23/74 (31%), Positives = 41/74 (55%)
Frame = +1
Query: 289 VGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSSTDYSITAGSK 468
VG AAAF+ + + V + I LVD+ + + E D+ H F +A+I + Y +G+
Sbjct: 2 VGSAAAFACIMRGVASEIVLVDLDTARAQAEAEDIAHAVPFSVSARIVAG-GYDDLSGAD 60
Query: 469 ICVVTAGVRQREGD 510
+ ++ GV Q+ G+
Sbjct: 61 VVILACGVSQKPGE 74
>UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140;
Bacteria|Rep: L-lactate dehydrogenase - Streptococcus
pneumoniae
Length = 328
Score = 88.2 bits (209), Expect = 2e-16
Identities = 40/72 (55%), Positives = 54/72 (75%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RLDLV +N + K I+ Q+++ I ++A+NPVD+LTY TWK SG PK RVIGSGT+
Sbjct: 93 TRLDLVGKNLAINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTS 152
Query: 690 LDSARFRYLLSD 725
LDSARFR L++
Sbjct: 153 LDSARFRQALAE 164
>UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2;
Ascomycota|Rep: Probable L-lactate dehydrogenase -
Schizosaccharomyces pombe (Fission yeast)
Length = 330
Score = 88.2 bits (209), Expect = 2e-16
Identities = 36/70 (51%), Positives = 56/70 (80%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+R+DL++ N + K+I+ ++ KY+ D IL++A+NPVD+LTY T K++G P RVIGSGT
Sbjct: 104 TRMDLLKANISIFKEILREVTKYTKDAILLVATNPVDVLTYATLKLTGFPAERVIGSGTI 163
Query: 690 LDSARFRYLL 719
+D+ARF+YL+
Sbjct: 164 IDTARFQYLI 173
Score = 57.2 bits (132), Expect = 4e-07
Identities = 27/83 (32%), Positives = 42/83 (50%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 441
K+ IVG G VG AF++L + I ++D+ K +GE MDL H + ++
Sbjct: 22 KIVIVGAGNVGSTTAFTLLLSGLAAEIVIIDLNKKKAEGEAMDLNHAAPLSHETRVYLG- 80
Query: 442 DYSITAGSKICVVTAGVRQREGD 510
DY + V+TAG Q+ G+
Sbjct: 81 DYKDCKDATAVVITAGKNQKPGE 103
>UniRef50_A6NLX8 Cluster: L-lactate dehydrogenase; n=4;
Eutheria|Rep: L-lactate dehydrogenase - Homo sapiens
(Human)
Length = 253
Score = 85.8 bits (203), Expect = 1e-15
Identities = 42/102 (41%), Positives = 62/102 (60%)
Frame = +1
Query: 208 VPEEAVPARAREGGRNWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMM 387
V E + E + KV+I G G VGMA A S+L + +++ +A VD+ KLKGE M
Sbjct: 53 VKSELIECFTSEEPFHHRKVSITGTGSVGMACATSILLKGLSDELAFVDLDEGKLKGETM 112
Query: 388 DLQHGSAFMRNAKIQSSTDYSITAGSKICVVTAGVRQREGDL 513
DLQH S FM+ + I S DY +TA + ++TAG R+ +G++
Sbjct: 113 DLQHDSPFMKMSNIVCSKDYLVTANPHLVIITAGARREKGEM 154
Score = 83.4 bits (197), Expect = 5e-15
Identities = 36/69 (52%), Positives = 51/69 (73%)
Frame = +3
Query: 513 RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNL 692
R +LV++N + K +I +++ SP L+I SNPVDILTYV WK+S PK+RVIGSG NL
Sbjct: 155 RFNLVRQNVAIFKLMISSIVQQSPLCKLIIVSNPVDILTYVAWKLSAFPKNRVIGSGCNL 214
Query: 693 DSARFRYLL 719
D+ RF++ +
Sbjct: 215 DTVRFQFFI 223
>UniRef50_Q4JY42 Cluster: L-lactate dehydrogenase; n=1;
Corynebacterium jeikeium K411|Rep: L-lactate
dehydrogenase - Corynebacterium jeikeium (strain K411)
Length = 326
Score = 85.8 bits (203), Expect = 1e-15
Identities = 39/70 (55%), Positives = 52/70 (74%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RLDLV +NT + K I+ ++ + + I ++ASNPVDIL+Y TWK SG+ RVIGSGT
Sbjct: 100 TRLDLVAKNTAIFKTIVGDVMSHGFNGIFLVASNPVDILSYATWKFSGMDSSRVIGSGTI 159
Query: 690 LDSARFRYLL 719
LD+ARFRY L
Sbjct: 160 LDTARFRYAL 169
Score = 53.6 bits (123), Expect = 5e-06
Identities = 26/98 (26%), Positives = 54/98 (55%), Gaps = 2/98 (2%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFM-RNAKIQS 435
SK+ ++G G VG+A A++++ Q +T+++A++D+ K G + DL H + N ++
Sbjct: 16 SKIVLIGAGDVGIAYAYTLVNQGLTDHLAIIDLDERKTWGHVQDLNHAVPWSHHNTRVTV 75
Query: 436 STDYSITAGSKICVVTAGVRQREGDL-VSISCRETPMF 546
T + +C + AG Q+ G+ + + + T +F
Sbjct: 76 GTYEDCRDAAMVC-ICAGAAQKPGETRLDLVAKNTAIF 112
>UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia
burgdorferi group|Rep: L-lactate dehydrogenase -
Borrelia burgdorferi (Lyme disease spirochete)
Length = 316
Score = 85.8 bits (203), Expect = 1e-15
Identities = 40/72 (55%), Positives = 52/72 (72%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RLDLV +N+ + K II ++ D I V+ASNPVDI+TYVT K S P H+VIG+GT
Sbjct: 90 TRLDLVDKNSKIFKDIITNVVSSGFDGIFVVASNPVDIMTYVTMKYSKFPIHKVIGTGTI 149
Query: 690 LDSARFRYLLSD 725
LD++R RY LSD
Sbjct: 150 LDTSRLRYFLSD 161
Score = 61.7 bits (143), Expect = 2e-08
Identities = 30/86 (34%), Positives = 53/86 (61%), Gaps = 2/86 (2%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQN-VTNNIALVDMMADKLKGEMMDLQHGSAFM-RNAKIQ 432
+KV ++G G VG + A+++ N + + + ++D+ +K KGE+MDL HG F+ +N +
Sbjct: 5 NKVVLIGAGGVGSSFAYALTIDNSLVHELVIIDVNENKAKGEVMDLNHGQMFLKKNINVL 64
Query: 433 SSTDYSITAGSKICVVTAGVRQREGD 510
T Y A + I V+TAG+ Q+ G+
Sbjct: 65 FGT-YKDCANADIVVITAGLNQKPGE 89
>UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibacter
ruber DSM 13855|Rep: L-lactate dehydrogenase -
Salinibacter ruber (strain DSM 13855)
Length = 316
Score = 85.4 bits (202), Expect = 1e-15
Identities = 37/70 (52%), Positives = 56/70 (80%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RL L+QRN ++ ++II QL K++P+ ILV+A+NPVD+LTY+ ++S P R++G+GT
Sbjct: 89 TRLGLLQRNAEIFREIIIQLDKHAPNAILVVATNPVDVLTYICQELSSRPNRRILGTGTL 148
Query: 690 LDSARFRYLL 719
LD+ARFR LL
Sbjct: 149 LDTARFRALL 158
Score = 58.4 bits (135), Expect = 2e-07
Identities = 29/82 (35%), Positives = 48/82 (58%)
Frame = +1
Query: 265 VTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSSTD 444
V IVG G VG AAA++M Q++ + I L+D + +GE MDL HG + + + +
Sbjct: 7 VGIVGTGNVGTAAAYAMFNQSLASEILLLDQDTRRAEGEAMDLMHGQQLVGGITCR-AVE 65
Query: 445 YSITAGSKICVVTAGVRQREGD 510
Y+ + ++I V++AG Q+ D
Sbjct: 66 YAALSNAQIIVLSAGASQQSPD 87
>UniRef50_Q8IX04 Cluster: Ubiquitin-conjugating enzyme E2 variant 3;
n=15; Euteleostomi|Rep: Ubiquitin-conjugating enzyme E2
variant 3 - Homo sapiens (Human)
Length = 471
Score = 85.0 bits (201), Expect = 2e-15
Identities = 36/72 (50%), Positives = 54/72 (75%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
S LD+VQ N D+ + ++P L YS ++L++AS PV+I+TYVTWK+S P +RVIG G N
Sbjct: 261 SYLDVVQSNVDMFRALVPALGHYSQHSVLLVASQPVEIMTYVTWKLSTFPANRVIGIGCN 320
Query: 690 LDSARFRYLLSD 725
LDS R +Y++++
Sbjct: 321 LDSQRLQYIITN 332
Score = 44.0 bits (99), Expect = 0.004
Identities = 24/94 (25%), Positives = 50/94 (53%)
Frame = +1
Query: 202 DGVPEEAVPARAREGGRNWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGE 381
+GV + + A + +K+T+VG G++G+A ++ + + + + L+D +++ KG
Sbjct: 164 EGVSDTNSKSWANHENKTVNKITVVGGGELGIACTLAISAKGIADRLVLLD-LSEGTKGA 222
Query: 382 MMDLQHGSAFMRNAKIQSSTDYSITAGSKICVVT 483
MDL+ ++ S D S +A SK+ + T
Sbjct: 223 TMDLE----IFNLPNVEISKDLSASAHSKVVIFT 252
>UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17;
Bacteria|Rep: L-lactate dehydrogenase 2 -
Bifidobacterium longum
Length = 320
Score = 85.0 bits (201), Expect = 2e-15
Identities = 36/71 (50%), Positives = 56/71 (78%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SRL+LV ++LK I+P L+K +P+ I ++ +NPVDI T+V K++GLP++++ GSGTN
Sbjct: 93 SRLELVGATVNILKAIMPNLVKVAPNAIYMLITNPVDIATHVAQKLTGLPENQIFGSGTN 152
Query: 690 LDSARFRYLLS 722
LDSAR R+L++
Sbjct: 153 LDSARLRFLIA 163
Score = 65.3 bits (152), Expect = 1e-09
Identities = 28/83 (33%), Positives = 48/83 (57%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 438
+K+ ++G G VG AF+ + + I L D+ ++++ E++D+QHGS+F I S
Sbjct: 9 TKLAVIGAGAVGSTLAFAAAQRGIAREIVLEDIAKERVEAEVLDMQHGSSFYPTVSIDGS 68
Query: 439 TDYSITAGSKICVVTAGVRQREG 507
D I + + V+TAG RQ+ G
Sbjct: 69 DDPEICRDADMVVITAGPRQKPG 91
>UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4;
Lactobacillus|Rep: L-lactate dehydrogenase -
Lactobacillus reuteri
Length = 312
Score = 84.6 bits (200), Expect = 2e-15
Identities = 41/71 (57%), Positives = 52/71 (73%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RLDLV +NT +LK II ++K + VI+SNPVDILT + +ISG PK RVIG+GT+
Sbjct: 91 TRLDLVNKNTTILKSIIKPIVKSGFTGVFVISSNPVDILTTIAQRISGFPKERVIGTGTS 150
Query: 690 LDSARFRYLLS 722
LDS R R LLS
Sbjct: 151 LDSMRLRVLLS 161
Score = 48.0 bits (109), Expect = 2e-04
Identities = 28/84 (33%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSML-TQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 438
KV ++G G VG + AFS L + N + + LVD K G+ DL + KI +
Sbjct: 8 KVVLIGDGAVGSSFAFSFLQSTNEVDELVLVDRTKSKAVGDAADLADITPLTNPVKIYAG 67
Query: 439 TDYSITAGSKICVVTAGVRQREGD 510
T Y A + + V+TAG+ ++ G+
Sbjct: 68 T-YEDAADADVVVITAGIPRKPGE 90
>UniRef50_A4QXM2 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 323
Score = 83.8 bits (198), Expect = 4e-15
Identities = 35/67 (52%), Positives = 53/67 (79%), Gaps = 1/67 (1%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKY-SPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGT 686
SR++L Q N + K+I+P+++++ SPD +L++++NPVD++TY K SG P H VIGSGT
Sbjct: 96 SRMELAQSNWGIFKEIVPKVVQHASPDALLLVSANPVDVMTYAAVKFSGFPAHSVIGSGT 155
Query: 687 NLDSARF 707
+LDSARF
Sbjct: 156 SLDSARF 162
Score = 66.9 bits (156), Expect = 5e-10
Identities = 31/82 (37%), Positives = 47/82 (57%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 441
KV IVG G VG A+++L I L+D+ DK +GE+MDL H + F+ +I +
Sbjct: 14 KVVIVGAGYVGSTTAYTLLMNRAAAEIVLIDVDKDKTEGEVMDLVHAAPFLHQTRIWAG- 72
Query: 442 DYSITAGSKICVVTAGVRQREG 507
DY G+ + ++TAG Q+ G
Sbjct: 73 DYEDCKGASVIILTAGANQKPG 94
>UniRef50_UPI0000DB7268 Cluster: PREDICTED: similar to L-lactate
dehydrogenase A chain (LDH-A) (LDH muscle subunit)
(LDH-M); n=2; Apis mellifera|Rep: PREDICTED: similar to
L-lactate dehydrogenase A chain (LDH-A) (LDH muscle
subunit) (LDH-M) - Apis mellifera
Length = 348
Score = 82.2 bits (194), Expect = 1e-14
Identities = 33/67 (49%), Positives = 52/67 (77%)
Frame = +3
Query: 522 LVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSA 701
L+++N ++ K +IP++ KY+P++IL+I + PVDIL+Y K+SG P HRV+G GT LDS
Sbjct: 121 LLEQNLNIFKDVIPKVCKYAPNSILLIVTAPVDILSYAAMKLSGFPPHRVVGLGTFLDSC 180
Query: 702 RFRYLLS 722
RF+Y ++
Sbjct: 181 RFQYFIA 187
Score = 64.1 bits (149), Expect = 3e-09
Identities = 27/78 (34%), Positives = 46/78 (58%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 441
K+ IVG G G+A ++L + + + + +D+ + K E D+ HG+AF+ N KI +
Sbjct: 34 KIVIVGSGYTGVAIGIAILFKRLASELVFIDVNEELAKAEAEDISHGAAFLGNPKIIGTK 93
Query: 442 DYSITAGSKICVVTAGVR 495
DYS+ + +CV+T G R
Sbjct: 94 DYSLARDATVCVITIGDR 111
>UniRef50_A5KJY5 Cluster: Putative uncharacterized protein; n=2;
Ruminococcus|Rep: Putative uncharacterized protein -
Ruminococcus torques ATCC 27756
Length = 316
Score = 81.8 bits (193), Expect = 2e-14
Identities = 38/72 (52%), Positives = 55/72 (76%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RLDLVQ+N +++ II ++ + + + IL+I SNPVDILT V + SG PK RVIGSGT
Sbjct: 88 TRLDLVQKNAAIMRSIIKEIKRVNCEGILLIVSNPVDILTEVALRESGFPKERVIGSGTV 147
Query: 690 LDSARFRYLLSD 725
LD+AR +Y++S+
Sbjct: 148 LDTARLKYIISE 159
Score = 55.2 bits (127), Expect = 2e-06
Identities = 25/86 (29%), Positives = 46/86 (53%)
Frame = +1
Query: 253 NWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQ 432
N K ++G G VG A++++ + + + + L+D K +GE MD+ HG F I
Sbjct: 3 NIQKAAVIGCGFVGSTIAYTLMQKGLFSEMVLLDANKAKAEGEAMDISHGLPFTHAMDIY 62
Query: 433 SSTDYSITAGSKICVVTAGVRQREGD 510
+ +Y A + + ++TAG Q+ G+
Sbjct: 63 AG-EYEDIADASVVIITAGANQKPGE 87
>UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;
Clostridium|Rep: L-lactate dehydrogenase precursor -
Clostridium thermocellum (strain ATCC 27405 / DSM 1237)
Length = 318
Score = 81.8 bits (193), Expect = 2e-14
Identities = 37/72 (51%), Positives = 53/72 (73%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RLDL ++N + K++ ++KY ++++ SNPVDI+TY+ K SGLP +VIGSGT
Sbjct: 91 TRLDLAKKNVMIAKEVTQNIMKYYNHGVILVVSNPVDIITYMIQKWSGLPVGKVIGSGTV 150
Query: 690 LDSARFRYLLSD 725
LDS RFRYLLS+
Sbjct: 151 LDSIRFRYLLSE 162
Score = 68.5 bits (160), Expect = 2e-10
Identities = 33/84 (39%), Positives = 48/84 (57%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 438
SKV I+G G VG +AAF+M + N + L+D+ +K GE MD+ HG FM + +
Sbjct: 8 SKVAIIGAGFVGASAAFTMALRQTANELVLIDVFKEKAIGEAMDINHGLPFMGQMSLYAG 67
Query: 439 TDYSITAGSKICVVTAGVRQREGD 510
DYS + VVTAG ++ G+
Sbjct: 68 -DYSDVKDCDVIVVTAGANRKPGE 90
>UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep: Malate/lactate
dehydrogenase - Leptospirillum sp. Group II UBA
Length = 320
Score = 81.4 bits (192), Expect = 2e-14
Identities = 29/72 (40%), Positives = 55/72 (76%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SR DL+ +N D++ ++ ++ K++PD+++++ +NP+D++ Y+ WK++G P+ RVIG G
Sbjct: 91 SREDLLHKNGDIMIEVAEKIRKHAPDSVVIMVTNPMDLMAYILWKVTGFPRERVIGMGGA 150
Query: 690 LDSARFRYLLSD 725
LDS+RF Y +S+
Sbjct: 151 LDSSRFAYFVSE 162
>UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2;
Euryarchaeota|Rep: Malate dehydrogenase - Methanopyrus
kandleri
Length = 317
Score = 81.0 bits (191), Expect = 3e-14
Identities = 34/71 (47%), Positives = 55/71 (77%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RLDL + N ++K+ + + + +P+ I+++ +NPVD+LTYV K+SGLPK+RVIG GT+
Sbjct: 90 TRLDLTKDNAAIIKKYLEGVAEENPEAIVLVVTNPVDVLTYVALKVSGLPKNRVIGLGTH 149
Query: 690 LDSARFRYLLS 722
LDS RF+ L++
Sbjct: 150 LDSMRFKVLIA 160
>UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8;
Lactobacillus|Rep: L-lactate dehydrogenase 2 -
Lactobacillus plantarum
Length = 309
Score = 81.0 bits (191), Expect = 3e-14
Identities = 37/71 (52%), Positives = 53/71 (74%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SRLDL+ RNT +L+ I+ ++ + VI+SNPVDILT +T ++SG P+HRVIG+GT+
Sbjct: 89 SRLDLINRNTKILESIVKPVVASGFNGCFVISSNPVDILTSMTQRLSGFPRHRVIGTGTS 148
Query: 690 LDSARFRYLLS 722
LD+AR R L+
Sbjct: 149 LDTARLRVALA 159
Score = 52.8 bits (121), Expect = 8e-06
Identities = 27/83 (32%), Positives = 48/83 (57%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 441
KV IVG G VG + AFS++ + + +VD++ +G++ DL+ +AF I +
Sbjct: 7 KVVIVGDGSVGSSFAFSLVQNCALDELVIVDLVKTHAEGDVKDLEDVAAFTNATNIHTG- 65
Query: 442 DYSITAGSKICVVTAGVRQREGD 510
+Y+ + I V+TAGV ++ G+
Sbjct: 66 EYADARDADIVVITAGVPRKPGE 88
>UniRef50_Q81XJ7 Cluster: L-lactate dehydrogenase 3; n=13;
Firmicutes|Rep: L-lactate dehydrogenase 3 - Bacillus
anthracis
Length = 316
Score = 79.8 bits (188), Expect = 6e-14
Identities = 34/72 (47%), Positives = 55/72 (76%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SRLD + + +++ ++ +++ D I ++ASNPVDI+TY WK+SGLP++RVIG+GT+
Sbjct: 90 SRLDTLGASAKIMESVVGGVMESGFDGIFLLASNPVDIITYQVWKLSGLPRNRVIGTGTS 149
Query: 690 LDSARFRYLLSD 725
LDS+R R +LS+
Sbjct: 150 LDSSRLRTILSE 161
Score = 51.2 bits (117), Expect = 3e-05
Identities = 25/86 (29%), Positives = 42/86 (48%)
Frame = +1
Query: 250 RNWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKI 429
R+ K+ I+G G VG + A+S++ Q + + L+D+ ++ GE MDL H F
Sbjct: 3 RHTRKIAIIGTGLVGSSCAYSIVNQGICEELLLIDINHERAVGEAMDLSHCINFTNTRTK 62
Query: 430 QSSTDYSITAGSKICVVTAGVRQREG 507
+ Y I ++TAG + G
Sbjct: 63 VYAGSYEDCKDMDIVIITAGPAPKPG 88
>UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28;
Bacteroidetes|Rep: Malate dehydrogenase - Bacteroides
fragilis
Length = 313
Score = 79.4 bits (187), Expect = 8e-14
Identities = 35/71 (49%), Positives = 51/71 (71%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+R +L+ N ++K + L+KYSP+ I+V+ SNP+D +TY+ K GLPK+RVIG G
Sbjct: 88 TREELIGVNAGIVKSVAENLLKYSPNAIIVVISNPMDTMTYLALKSLGLPKNRVIGMGGA 147
Query: 690 LDSARFRYLLS 722
LDS+RF+Y LS
Sbjct: 148 LDSSRFKYFLS 158
Score = 48.8 bits (111), Expect = 1e-04
Identities = 24/85 (28%), Positives = 45/85 (52%), Gaps = 2/85 (2%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFM--RNAKIQ 432
SKVT+VG G VG A + V + + ++D+ +G+ MD+ + + +
Sbjct: 2 SKVTVVGAGNVGATCANVLAFNEVADEVVMLDVKEGVSEGKAMDMMQTAQLLGFDTTIVG 61
Query: 433 SSTDYSITAGSKICVVTAGVRQREG 507
+ DY+ TA S + V+T+G+ ++ G
Sbjct: 62 CTNDYAQTANSDVVVITSGIPRKPG 86
>UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7;
Bacteria|Rep: L-lactate dehydrogenase - Deinococcus
radiodurans
Length = 304
Score = 79.4 bits (187), Expect = 8e-14
Identities = 34/71 (47%), Positives = 56/71 (78%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SRLDL+++N D+ ++++PQ+ + +PD +L++ SNPVD+LT + +++ P VIGSGT
Sbjct: 84 SRLDLLEKNADIFRELVPQITRAAPDAVLLVTSNPVDLLTDLATQLA--PGQPVIGSGTV 141
Query: 690 LDSARFRYLLS 722
LDSARFR+L++
Sbjct: 142 LDSARFRHLMA 152
Score = 50.0 bits (114), Expect = 6e-05
Identities = 24/83 (28%), Positives = 45/83 (54%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 441
KV +VG G VG AAF+++ + + + LVD D+ + E D+ H + ++
Sbjct: 2 KVGVVGTGFVGSTAAFALVLRGSCSELVLVDRDEDRAQAEAEDIAHAAPVSHGTRVWHG- 60
Query: 442 DYSITAGSKICVVTAGVRQREGD 510
+S A +++ ++TAG Q+ G+
Sbjct: 61 GHSELADAQVVILTAGANQKPGE 83
>UniRef50_Q8ELF0 Cluster: L-lactate dehydrogenase; n=5;
Bacillaceae|Rep: L-lactate dehydrogenase -
Oceanobacillus iheyensis
Length = 321
Score = 79.0 bits (186), Expect = 1e-13
Identities = 37/72 (51%), Positives = 50/72 (69%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RLDLV++N + K+I+ ++ + I +IA+NPVDILT SGLP HRVIGSGT
Sbjct: 93 TRLDLVEKNMKIFKEIVTDVMNSGFNGIFLIATNPVDILTQAVISFSGLPPHRVIGSGTT 152
Query: 690 LDSARFRYLLSD 725
LD+AR RY L +
Sbjct: 153 LDTARLRYELGE 164
Score = 64.9 bits (151), Expect = 2e-09
Identities = 29/84 (34%), Positives = 50/84 (59%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 438
++V ++G G VG++ AF+++ Q VT +A++D+ ADK G++MDL HG AF +
Sbjct: 9 NRVVLIGGGSVGVSYAFALMNQGVTEELAIIDLDADKALGDVMDLNHGKAFAPSLTNVWL 68
Query: 439 TDYSITAGSKICVVTAGVRQREGD 510
+Y + I + AG Q+ G+
Sbjct: 69 GEYGDCKDADIVCICAGANQQSGE 92
>UniRef50_Q3U1V6 Cluster: Ubiquitin-conjugating enzyme E2 variant 3;
n=23; Tetrapoda|Rep: Ubiquitin-conjugating enzyme E2
variant 3 - Mus musculus (Mouse)
Length = 471
Score = 77.4 bits (182), Expect = 3e-13
Identities = 33/71 (46%), Positives = 49/71 (69%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
S L VQ N D+ + ++P L YS +L++AS PV+I++YVTWK+S P RV+G G N
Sbjct: 261 SYLHAVQSNVDMFRALVPALGHYSQHAVLLVASQPVEIMSYVTWKLSTFPATRVVGIGCN 320
Query: 690 LDSARFRYLLS 722
LDS R +Y+++
Sbjct: 321 LDSQRLQYIIT 331
Score = 38.7 bits (86), Expect = 0.14
Identities = 21/76 (27%), Positives = 41/76 (53%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 438
+K+T+VG G +G+A ++ + + + + L+D ++D + MDL ++ S
Sbjct: 183 NKITVVGSGDLGIACTLAISAKGIADKLLLLD-LSDGMSQGTMDLD----IFNLPNVEIS 237
Query: 439 TDYSITAGSKICVVTA 486
D S +A SK+ + TA
Sbjct: 238 KDLSASAHSKVVIFTA 253
>UniRef50_A1U9V0 Cluster: Lactate/malate dehydrogenase; n=6;
Actinomycetales|Rep: Lactate/malate dehydrogenase -
Mycobacterium sp. (strain KMS)
Length = 329
Score = 76.6 bits (180), Expect = 6e-13
Identities = 35/82 (42%), Positives = 52/82 (63%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 441
KV+I+G G VG A A++ L + +AL D + K++ E++DL HGS F+ ++ S
Sbjct: 20 KVSIIGAGSVGTAIAYACLIRGSAGTLALYDTNSAKVRAEVLDLNHGSQFVPECRVGGSD 79
Query: 442 DYSITAGSKICVVTAGVRQREG 507
D ++TAGS I VVTAG +Q G
Sbjct: 80 DIAVTAGSAIVVVTAGAKQHPG 101
Score = 70.9 bits (166), Expect = 3e-11
Identities = 29/71 (40%), Positives = 48/71 (67%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SRLDL N + + + PQL+++SPD +++ +NPVD++TY + ++ G+GT
Sbjct: 103 SRLDLAAANVAMAQTLTPQLLEHSPDAVVIFVTNPVDVVTYAASSVVDAQPGQIFGTGTV 162
Query: 690 LDSARFRYLLS 722
LDS+RFRYL++
Sbjct: 163 LDSSRFRYLVA 173
>UniRef50_Q6NPB9 Cluster: AT22132p; n=2; Drosophila
melanogaster|Rep: AT22132p - Drosophila melanogaster
(Fruit fly)
Length = 361
Score = 75.8 bits (178), Expect = 1e-12
Identities = 30/72 (41%), Positives = 51/72 (70%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SRL +Q+ ++LK+ +P+L++ SP+ +I SNP D++TY +I+ LPKHR +G +
Sbjct: 134 SRLAAMQKTVEILKKAVPKLVELSPNATFIIISNPADVMTYAVQRITNLPKHRCFTTGCH 193
Query: 690 LDSARFRYLLSD 725
LD+ RFR L+++
Sbjct: 194 LDTVRFRNLIAN 205
Score = 68.1 bits (159), Expect = 2e-10
Identities = 29/79 (36%), Positives = 51/79 (64%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 438
SK+++VG GQVG A + +L +N+T N+ ++D+ + K E +D QH SAF+ +A++
Sbjct: 49 SKISVVGAGQVGTAISAMLLLRNLTKNLVILDINYELAKAEALDFQHASAFLSDARVVPC 108
Query: 439 TDYSITAGSKICVVTAGVR 495
D + + S + ++TAG R
Sbjct: 109 GDSTNSKDSDVVIITAGAR 127
>UniRef50_A6M0Q2 Cluster: L-lactate dehydrogenase; n=1; Clostridium
beijerinckii NCIMB 8052|Rep: L-lactate dehydrogenase -
Clostridium beijerinckii NCIMB 8052
Length = 316
Score = 75.4 bits (177), Expect = 1e-12
Identities = 31/72 (43%), Positives = 52/72 (72%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RLD++++ ++ I+P ++K I+V+ +NPVD+++Y K+SGLP +VIG+GT
Sbjct: 90 TRLDMLEKAAGIMNNIVPNIMKSGFSGIIVVITNPVDVMSYYVHKLSGLPASKVIGTGTA 149
Query: 690 LDSARFRYLLSD 725
LDSAR +Y L+D
Sbjct: 150 LDSARLKYHLAD 161
Score = 50.0 bits (114), Expect = 6e-05
Identities = 26/78 (33%), Positives = 40/78 (51%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 438
SKV IVG G VG A AF M+ +V +++ L+D+ +K E DLQH + +
Sbjct: 6 SKVVIVGTGSVGAAVAFDMVMNHVCDDLILIDINKEKSWAEATDLQHSLGYSGSKMRVKD 65
Query: 439 TDYSITAGSKICVVTAGV 492
+Y + I V+ A +
Sbjct: 66 GEYEECNDADIVVIAAAL 83
>UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4;
Thermotogaceae|Rep: L-lactate dehydrogenase - Thermotoga
maritima
Length = 319
Score = 75.4 bits (177), Expect = 1e-12
Identities = 34/71 (47%), Positives = 51/71 (71%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RL L+ RN V+K+I + KY+PD+I+++ +NPVD+LTY K SG+ +V GSGT
Sbjct: 84 TRLQLLGRNARVMKEIARNVSKYAPDSIVIVVTNPVDVLTYFFLKESGMDPRKVFGSGTV 143
Query: 690 LDSARFRYLLS 722
LD+AR R L++
Sbjct: 144 LDTARLRTLIA 154
Score = 66.9 bits (156), Expect = 5e-10
Identities = 31/83 (37%), Positives = 52/83 (62%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 441
K+ IVG+G+VG + AF++L + + L+D+ + +G+ +DL HG+ F R A I +
Sbjct: 2 KIGIVGLGRVGSSTAFALLMKGFAREMVLIDVDKKRAEGDALDLIHGTPFTRRANIYAG- 60
Query: 442 DYSITAGSKICVVTAGVRQREGD 510
DY+ GS + +V AGV Q+ G+
Sbjct: 61 DYADLKGSDVVIVAAGVPQKPGE 83
>UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=2;
Desulfitobacterium hafniense|Rep: Malate dehydrogenase,
NAD-dependent - Desulfitobacterium hafniense (strain
DCB-2)
Length = 320
Score = 74.1 bits (174), Expect = 3e-12
Identities = 32/71 (45%), Positives = 51/71 (71%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SR +L N ++ ++ Q++++SP++ L+I SNPVDI+TYV +K SG ++R+IG
Sbjct: 88 SRNELCDINAGIVTHVVRQVVQHSPNSTLIILSNPVDIMTYVAFKESGFKRNRIIGQSGV 147
Query: 690 LDSARFRYLLS 722
LDSARFRY ++
Sbjct: 148 LDSARFRYFVA 158
Score = 48.4 bits (110), Expect = 2e-04
Identities = 25/86 (29%), Positives = 48/86 (55%), Gaps = 3/86 (3%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADK--LKGEMMDLQHGSAFMRNA-KI 429
+K++++G G G AF ML +I L+D A++ KG+ +D+ R++ ++
Sbjct: 2 AKISVIGSGFTGTTTAF-MLAMKGLGDIVLLDTQANENPTKGKALDIMEAGPLTRSSVRV 60
Query: 430 QSSTDYSITAGSKICVVTAGVRQREG 507
++DY T S + V+TAG+ ++ G
Sbjct: 61 TGTSDYQDTLDSDVVVITAGIARKPG 86
>UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4;
Thermoplasmatales|Rep: Malate dehydrogenase -
Thermoplasma volcanium
Length = 325
Score = 74.1 bits (174), Expect = 3e-12
Identities = 32/71 (45%), Positives = 48/71 (67%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SR DL +N +++ + + KYSPD+I+V+ SNP DI+ Y KISG+ R++G G +
Sbjct: 93 SREDLFDKNVEIIADVSKNIKKYSPDSIIVVVSNPADIMAYALQKISGVDPQRIMGLGGS 152
Query: 690 LDSARFRYLLS 722
LDS+RFR L+
Sbjct: 153 LDSSRFRTFLA 163
>UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|Rep:
Malate dehydrogenase 1 - Aquifex aeolicus
Length = 335
Score = 73.3 bits (172), Expect = 5e-12
Identities = 30/72 (41%), Positives = 51/72 (70%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SR DL++ N ++ I ++ +Y+PD I+++ +NPVD++TYV +K+ PK+RV+G
Sbjct: 102 SREDLLEANIRIISVIADRIKRYAPDAIVIVVTNPVDVMTYVAYKLLNFPKNRVMGMAGV 161
Query: 690 LDSARFRYLLSD 725
LDSARF+ +S+
Sbjct: 162 LDSARFKTFISE 173
>UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2;
Propionibacterium acnes|Rep: L-lactate dehydrogenase -
Propionibacterium acnes
Length = 319
Score = 73.3 bits (172), Expect = 5e-12
Identities = 30/70 (42%), Positives = 51/70 (72%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RLDL N ++L+ ++PQL++ SP+ + V+ +NP D+LT V + +GLP +RV +GT
Sbjct: 94 TRLDLAGVNANILRSLMPQLVEQSPNALFVLVTNPCDVLTVVAQEATGLPANRVFSTGTM 153
Query: 690 LDSARFRYLL 719
LD++R R+L+
Sbjct: 154 LDTSRLRWLI 163
Score = 64.1 bits (149), Expect = 3e-09
Identities = 31/86 (36%), Positives = 49/86 (56%)
Frame = +1
Query: 250 RNWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKI 429
R SK+++VG G VG + A++ L + ++L D+ DK++ E+ DL HG+ F A +
Sbjct: 8 RRASKISVVGAGSVGSSLAYACLIRGSAGLVSLYDIAKDKVEAEVADLAHGTQF-TPASV 66
Query: 430 QSSTDYSITAGSKICVVTAGVRQREG 507
D TA S + +TAG RQ+ G
Sbjct: 67 MGGADVHDTADSDVVFITAGARQKPG 92
>UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2;
Desulfovibrio vulgaris subsp. vulgaris|Rep: L-lactate
dehydrogenase - Desulfovibrio vulgaris (strain
Hildenborough / ATCC 29579 / NCIMB8303)
Length = 309
Score = 73.3 bits (172), Expect = 5e-12
Identities = 33/67 (49%), Positives = 50/67 (74%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SRLDLV+ N + + I+ +++Y+ D + ++A+NPVD+LT+V ++G+ RVIGSGT
Sbjct: 85 SRLDLVRVNAGITRDILTAVMQYADDPLYIMATNPVDVLTHVARTVTGVAPGRVIGSGTV 144
Query: 690 LDSARFR 710
LDSARFR
Sbjct: 145 LDSARFR 151
Score = 62.9 bits (146), Expect = 8e-09
Identities = 31/83 (37%), Positives = 50/83 (60%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 438
+++ ++GVG VGMA A++ + + N+I L+D A + +GE MDL A + +I+S
Sbjct: 2 NRIAVIGVGNVGMAFAYAAAIKRLANDIVLIDANAARAEGESMDLADAMALVGPVQIRSG 61
Query: 439 TDYSITAGSKICVVTAGVRQREG 507
Y G++I VVTAG +Q G
Sbjct: 62 -GYEQCEGARIVVVTAGAKQMPG 83
>UniRef50_Q4L941 Cluster: L-lactate dehydrogenase; n=1;
Staphylococcus haemolyticus JCSC1435|Rep: L-lactate
dehydrogenase - Staphylococcus haemolyticus (strain
JCSC1435)
Length = 318
Score = 72.5 bits (170), Expect = 1e-11
Identities = 31/71 (43%), Positives = 51/71 (71%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RL L++ N D+ +I +++ D V+ SNPVDI++YV ++S PK+++IGSGT+
Sbjct: 88 TRLKLLEDNVDIFVPMIQRIVDSGFDGYFVLPSNPVDIMSYVVKRVSNFPKNKIIGSGTS 147
Query: 690 LDSARFRYLLS 722
LD+ARF++ LS
Sbjct: 148 LDTARFQFFLS 158
>UniRef50_Q8RED8 Cluster: L-lactate dehydrogenase; n=3;
Fusobacterium nucleatum|Rep: L-lactate dehydrogenase -
Fusobacterium nucleatum subsp. nucleatum
Length = 318
Score = 72.5 bits (170), Expect = 1e-11
Identities = 33/78 (42%), Positives = 53/78 (67%)
Frame = +3
Query: 492 STTRR*SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRV 671
S T+ RL+ ++ + + +K +P ++K + I V +NPVDI+TY ++SG PK+RV
Sbjct: 82 SLTKNEQRLEELKGSLEAIKSFVPDVVKAGFNGIFVTITNPVDIVTYFVRELSGFPKNRV 141
Query: 672 IGSGTNLDSARFRYLLSD 725
IG+GT LDSAR + +LS+
Sbjct: 142 IGTGTGLDSARLKRILSE 159
Score = 43.6 bits (98), Expect = 0.005
Identities = 27/77 (35%), Positives = 40/77 (51%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 441
KV IVG+G VG A SML Q V + + L+D++ +K K +D +F+ + I
Sbjct: 6 KVGIVGIGHVGSHCALSMLLQGVCDEMVLMDIIPEKAKAHAIDCMDTISFLPHRAI--IR 63
Query: 442 DYSITAGSKICVVTAGV 492
D I SK+ V+ V
Sbjct: 64 DGGIQELSKMDVIVISV 80
>UniRef50_UPI00015B6427 Cluster: PREDICTED: similar to lactate
dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to lactate dehydrogenase - Nasonia vitripennis
Length = 352
Score = 72.1 bits (169), Expect = 1e-11
Identities = 28/67 (41%), Positives = 51/67 (76%)
Frame = +3
Query: 522 LVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSA 701
++Q+N +LK+++P L KY+P+++L++ S PVD+L+++ K+SG P RV+G GT LD+
Sbjct: 126 VLQQNALLLKELVPSLTKYAPNSVLLVVSEPVDVLSHLAMKLSGFPSQRVLGLGTLLDNC 185
Query: 702 RFRYLLS 722
R ++ L+
Sbjct: 186 RLQHELA 192
Score = 60.9 bits (141), Expect = 3e-08
Identities = 28/82 (34%), Positives = 49/82 (59%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 438
+K+ IVG G VG+A A +L + + + L+D + + E D+ + F+ + KI++S
Sbjct: 38 TKIVIVGSGPVGVAVAVGLLFKRLAAELILMDENPEMARAEAEDIAAAAVFLGSPKIRAS 97
Query: 439 TDYSITAGSKICVVTAGVRQRE 504
TDYS + +CV+ AG +QR+
Sbjct: 98 TDYSEARDATLCVIAAGRQQRD 119
>UniRef50_Q185V1 Cluster: L-lactate dehydrogenase; n=3;
Clostridium|Rep: L-lactate dehydrogenase - Clostridium
difficile (strain 630)
Length = 322
Score = 71.3 bits (167), Expect = 2e-11
Identities = 32/72 (44%), Positives = 49/72 (68%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RLDL++ ++K I+ ++ D I V+ SNPVD++T W+ SG PK++VIG+GT
Sbjct: 95 TRLDLLRPTIGMIKSIVKPIVDSGFDGIFVVISNPVDVVTNYIWEKSGFPKNKVIGTGTA 154
Query: 690 LDSARFRYLLSD 725
LDS R R +LS+
Sbjct: 155 LDSTRLRRILSE 166
Score = 42.7 bits (96), Expect = 0.009
Identities = 23/75 (30%), Positives = 41/75 (54%), Gaps = 1/75 (1%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFM-RNAKIQSS 438
K++IVG G VG FS++TQ V + + ++D+ K K + +DL +++ I+
Sbjct: 7 KISIVGSGHVGSHCGFSLITQGVCDELFMIDIDESKSKAQALDLADAVSYLPHKVHIEKG 66
Query: 439 TDYSITAGSKICVVT 483
T +S S I V++
Sbjct: 67 T-FSDCKDSDIVVIS 80
>UniRef50_Q0UX88 Cluster: L-lactate dehydrogenase; n=2;
Phaeosphaeria nodorum|Rep: L-lactate dehydrogenase -
Phaeosphaeria nodorum (Septoria nodorum)
Length = 326
Score = 71.3 bits (167), Expect = 2e-11
Identities = 33/71 (46%), Positives = 50/71 (70%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SRL L+ RN ++L I + S T+L++ +NPVDIL Y +SGLP+++V+G+GT+
Sbjct: 89 SRLSLLTRNLNILSSIFDSMKPISAHTVLLLVANPVDILVYFARMMSGLPENQVLGTGTS 148
Query: 690 LDSARFRYLLS 722
LDSAR R +L+
Sbjct: 149 LDSARLRGVLA 159
Score = 51.6 bits (118), Expect = 2e-05
Identities = 25/82 (30%), Positives = 46/82 (56%)
Frame = +1
Query: 265 VTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSSTD 444
+ ++G G VG A++++ Q++ + LVD L G++ DL A R+ K++S T
Sbjct: 10 IAVIGCGDVGATLAYTLILQSICTEVLLVDPKTSLLDGQVRDL--SDATSRSTKVRSGT- 66
Query: 445 YSITAGSKICVVTAGVRQREGD 510
+ + I V+TAG +Q+ G+
Sbjct: 67 HQEAGQADIVVITAGAKQKTGE 88
>UniRef50_A1C5Q5 Cluster: L-lactate dehydrogenase; n=4;
Pezizomycotina|Rep: L-lactate dehydrogenase -
Aspergillus clavatus
Length = 312
Score = 70.9 bits (166), Expect = 3e-11
Identities = 32/64 (50%), Positives = 48/64 (75%)
Frame = +3
Query: 531 RNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFR 710
RN ++++IIP + + PDTIL++ SNPVD+LT V ++SGLP +V+GSGT L+S R R
Sbjct: 100 RNMGIVQKIIPAMRPFRPDTILLVVSNPVDLLTTVAQQLSGLPPTQVLGSGTLLESVRLR 159
Query: 711 YLLS 722
L++
Sbjct: 160 GLVA 163
Score = 41.1 bits (92), Expect = 0.027
Identities = 27/85 (31%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNA--KIQS 435
++ IVGVGQVG AAA +++ +V + LVD+ ++ +L S A +I++
Sbjct: 9 RIAIVGVGQVGGAAANALILGSVARELLLVDVKIPLRNAQVQELSDVSNMSGGAETRIRA 68
Query: 436 STDYSITAGSKICVVTAGVRQREGD 510
T Y I V+TAG + G+
Sbjct: 69 GT-YEEAGQCDIVVITAGSKYSVGE 92
>UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizopus
oryzae|Rep: L-lactate dehydrogenase A - Rhizopus oryzae
(Rhizopus delemar)
Length = 320
Score = 70.9 bits (166), Expect = 3e-11
Identities = 33/71 (46%), Positives = 48/71 (67%)
Frame = +3
Query: 513 RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNL 692
R L++RN VL+ II + PD ++++ +NPVDILT++ +SGLP ++VIGSGT L
Sbjct: 88 RTKLIERNFRVLQSIIGGMQPIRPDAVILVVANPVDILTHIAKTLSGLPPNQVIGSGTYL 147
Query: 693 DSARFRYLLSD 725
D+ R R L D
Sbjct: 148 DTTRLRVHLGD 158
Score = 54.4 bits (125), Expect = 3e-06
Identities = 27/84 (32%), Positives = 49/84 (58%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 438
SKV IVG G VG + A++++ +N+ I +VD+ D ++ +++DL ++ S
Sbjct: 5 SKVAIVGAGAVGASTAYALMFKNICTEIIIVDVNPDIVQAQVLDLADAASISHTPIRAGS 64
Query: 439 TDYSITAGSKICVVTAGVRQREGD 510
+ + + I V+TAG +QREG+
Sbjct: 65 AEEA--GQADIVVITAGAKQREGE 86
>UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1;
Thermosinus carboxydivorans Nor1|Rep: Lactate/malate
dehydrogenase - Thermosinus carboxydivorans Nor1
Length = 303
Score = 70.5 bits (165), Expect = 4e-11
Identities = 29/70 (41%), Positives = 51/70 (72%)
Frame = +3
Query: 513 RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNL 692
R+ L+ RN ++ ++ Q + YSP+ I+ + +NP+D++T + +++SGLP +RVIG GT L
Sbjct: 85 RVLLLSRNAALIADLVRQAVHYSPNCIIFMVTNPLDVMTQLAYQVSGLPANRVIGMGTVL 144
Query: 693 DSARFRYLLS 722
D+AR+R L+
Sbjct: 145 DTARYRSYLA 154
Score = 55.6 bits (128), Expect = 1e-06
Identities = 28/80 (35%), Positives = 48/80 (60%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 441
K+ IVG G+VG A ++ + + + + I +VD DK GE +D+ AF A+I+
Sbjct: 2 KIAIVGSGKVGAAIGYTAMLKGLAHEIVMVDAARDKAHGEALDMLQCLAFAPPARIRHG- 60
Query: 442 DYSITAGSKICVVTAGVRQR 501
+ + TAG+ I V+TAG+ ++
Sbjct: 61 EMADTAGADIVVITAGIPRK 80
>UniRef50_Q92BI0 Cluster: L-lactate dehydrogenase 2; n=18;
Bacteria|Rep: L-lactate dehydrogenase 2 - Listeria
innocua
Length = 311
Score = 70.5 bits (165), Expect = 4e-11
Identities = 30/72 (41%), Positives = 51/72 (70%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RLD ++ + ++ I+P+++K I +IA+NP DI+TY WK+SGLP+ +V+G+G
Sbjct: 89 TRLDELRSTSRIVASIVPEMMKGGFKGIFLIATNPCDIITYQVWKLSGLPREQVLGTGVW 148
Query: 690 LDSARFRYLLSD 725
LD+ R R LL++
Sbjct: 149 LDTTRLRRLLAE 160
Score = 48.0 bits (109), Expect = 2e-04
Identities = 26/74 (35%), Positives = 38/74 (51%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 441
KV I+G G VG AAA + + Q + LVD+ ++++G DL +AFM S
Sbjct: 5 KVMIIGAGNVGSAAAHAFVNQKFVEELILVDLNKERVEGNRKDLADAAAFMSGKMDISVR 64
Query: 442 DYSITAGSKICVVT 483
+ S A I V+T
Sbjct: 65 EASDCADVDIAVIT 78
>UniRef50_A0RPE9 Cluster: Malate dehydrogenase; n=1; Campylobacter
fetus subsp. fetus 82-40|Rep: Malate dehydrogenase -
Campylobacter fetus subsp. fetus (strain 82-40)
Length = 306
Score = 70.1 bits (164), Expect = 5e-11
Identities = 30/71 (42%), Positives = 46/71 (64%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SR DL N ++ + K++P +I+++ +NP+DI+ YV +K SG +H+VIG
Sbjct: 86 SRDDLAMMNAKIVSHSSKMVSKFAPKSIIIVVTNPLDIMVYVAFKESGFARHKVIGMAGE 145
Query: 690 LDSARFRYLLS 722
LDSARFRY +S
Sbjct: 146 LDSARFRYYMS 156
Score = 43.6 bits (98), Expect = 0.005
Identities = 22/83 (26%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMR-NAKIQSS 438
K+ I+G G VG + A ++++ V + L+D+ + + MDL +A + + I
Sbjct: 2 KIAIIGAGNVGASCASLLISRKVCKKVTLIDINKNLAIAKAMDLAQMAAVLNLDIDIFGG 61
Query: 439 TDYSITAGSKICVVTAGVRQREG 507
+Y + I V+TAG +++G
Sbjct: 62 DNYELLKDFDIVVITAGFARKDG 84
>UniRef50_Q5B0T8 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 237
Score = 70.1 bits (164), Expect = 5e-11
Identities = 31/70 (44%), Positives = 50/70 (71%)
Frame = +3
Query: 516 LDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLD 695
+D + RNT +++ II ++ + DT+L+I +NPVD++T + ++S LP +V+GSGT LD
Sbjct: 94 MDYLYRNTSIVRSIINEMKPFRSDTVLLIVANPVDLMTSLAKELSNLPSAQVLGSGTFLD 153
Query: 696 SARFRYLLSD 725
S R R LL+D
Sbjct: 154 SIRLRGLLAD 163
Score = 50.8 bits (116), Expect = 3e-05
Identities = 28/83 (33%), Positives = 45/83 (54%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 438
S++ IVGVGQVG AAA++++ ++ + + LVD A G++ DL + R+ S
Sbjct: 8 SRIAIVGVGQVGAAAAYALVLGSIADELLLVDTRAAWRDGQVRDLSDAAYASRSKTRVYS 67
Query: 439 TDYSITAGSKICVVTAGVRQREG 507
Y + I V+TAG + G
Sbjct: 68 ATYREASQCDIVVITAGSKYLYG 90
>UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobus
fulgidus|Rep: Malate dehydrogenase - Archaeoglobus
fulgidus
Length = 294
Score = 70.1 bits (164), Expect = 5e-11
Identities = 25/67 (37%), Positives = 47/67 (70%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RLDL +N ++K I ++++ +P++ +++ +NP+D++TY+ WK SG P++ V G G
Sbjct: 86 TRLDLAHKNAGIIKDIAKKIVENAPESKILVVTNPMDVMTYIMWKESGKPRNEVFGMGNQ 145
Query: 690 LDSARFR 710
LDS R +
Sbjct: 146 LDSQRLK 152
Score = 65.7 bits (153), Expect = 1e-09
Identities = 36/83 (43%), Positives = 50/83 (60%), Gaps = 1/83 (1%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFM-RNAKIQSS 438
K+ VG G+VG +AF+ L + IALVD+ D GE MDL H +A + + KI
Sbjct: 2 KLGFVGAGRVGSTSAFTCLLNLDVDEIALVDIAEDLAVGEAMDLAHAAAGIDKYPKIVGG 61
Query: 439 TDYSITAGSKICVVTAGVRQREG 507
DYS+ GS+I VVTAG+ ++ G
Sbjct: 62 ADYSLLKGSEIIVVTAGLARKPG 84
>UniRef50_P62056 Cluster: L-lactate dehydrogenase; n=2;
Bacteria|Rep: L-lactate dehydrogenase - Treponema
denticola
Length = 315
Score = 69.7 bits (163), Expect = 7e-11
Identities = 34/71 (47%), Positives = 47/71 (66%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+R+DL++RN ++ I + + +++I SNPVDILT K SG + RVIGSGT
Sbjct: 89 TRIDLLKRNASIITGIAKDIAESGCSGVMLIVSNPVDILTRAALKASGWERGRVIGSGTV 148
Query: 690 LDSARFRYLLS 722
LD+ARFRY LS
Sbjct: 149 LDTARFRYTLS 159
Score = 56.8 bits (131), Expect = 5e-07
Identities = 32/85 (37%), Positives = 47/85 (55%), Gaps = 2/85 (2%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQS-- 435
KVT+VG G VG A+++ + IA+ DM + +G+ +DL G F+ I +
Sbjct: 7 KVTVVGAGAVGSTFAYALAQSGYADEIAITDMNKNFAEGQALDLVQGLPFLPQVDIHAGD 66
Query: 436 STDYSITAGSKICVVTAGVRQREGD 510
TDY A S I VVTAG +Q+ G+
Sbjct: 67 KTDY---ADSDIVVVTAGAKQQSGE 88
>UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular
organisms|Rep: Malate dehydrogenase - Dehalococcoides
sp. (strain CBDB1)
Length = 307
Score = 69.3 bits (162), Expect = 9e-11
Identities = 28/65 (43%), Positives = 43/65 (66%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+R +L+ N ++ ++ +KYSP+ LV+ SNPVD +TY+ WK+SGLP+ RV+G
Sbjct: 86 TREELLAINQKIMTDVVSNCLKYSPEATLVVVSNPVDTMTYLAWKLSGLPRKRVVGLSGV 145
Query: 690 LDSAR 704
LD R
Sbjct: 146 LDGGR 150
Score = 49.6 bits (113), Expect = 8e-05
Identities = 25/83 (30%), Positives = 49/83 (59%), Gaps = 1/83 (1%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDL-QHGSAFMRNAKIQSS 438
K++++G G VG A ++ ++ + + ++D++ +G+ +D+ Q S I S
Sbjct: 3 KISVIGAGNVGATLAQRLIEKDFAD-VVMLDVVEGIPQGKALDISQSASVLGFRHTITGS 61
Query: 439 TDYSITAGSKICVVTAGVRQREG 507
DY+ TAGS+I V+TAG+ ++ G
Sbjct: 62 NDYAQTAGSEIVVITAGIARKPG 84
>UniRef50_P47698 Cluster: L-lactate dehydrogenase; n=2;
Mycoplasma|Rep: L-lactate dehydrogenase - Mycoplasma
genitalium
Length = 312
Score = 68.9 bits (161), Expect = 1e-10
Identities = 31/71 (43%), Positives = 50/71 (70%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RL L++ N +++K I ++ K + + +IASNPVDI++Y K++G ++VIGSGT
Sbjct: 89 TRLQLLEGNVEIMKSIAKEIKKSGFNGVTLIASNPVDIMSYTYLKVTGFEPNKVIGSGTL 148
Query: 690 LDSARFRYLLS 722
LDSAR RY ++
Sbjct: 149 LDSARLRYAIA 159
Score = 37.5 bits (83), Expect = 0.33
Identities = 21/82 (25%), Positives = 40/82 (48%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 441
K+ IVG G VG + ++ +T+ + + ++D+ G + DLQ S+ N +
Sbjct: 5 KIAIVGSGAVGTSFLYAAMTRALGSEYMIIDINEKAKVGNVFDLQDASSSCPNFGKVVAG 64
Query: 442 DYSITAGSKICVVTAGVRQREG 507
+YS ++AG Q++G
Sbjct: 65 EYSQLKDYDFIFISAGRPQKQG 86
>UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Rep:
Malate dehydrogenase - Brucella melitensis
Length = 320
Score = 68.5 bits (160), Expect = 2e-10
Identities = 31/72 (43%), Positives = 47/72 (65%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SR DL+ N V++Q+ + KY+P+ ++ +NP+D + + K SGLP H+V+G
Sbjct: 88 SRDDLLGINLKVMEQVGAGIKKYAPEAFVICITNPLDAMVWALQKFSGLPAHKVVGMAGV 147
Query: 690 LDSARFRYLLSD 725
LDSARFRY LS+
Sbjct: 148 LDSARFRYFLSE 159
Score = 37.5 bits (83), Expect = 0.33
Identities = 21/84 (25%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMR-NAKIQS 435
+K+ ++G G +G A + + ++ L D+ +G+ +D+ S +AK
Sbjct: 4 NKIALIGSGMIGGTLAHLAGLKEL-GDVVLFDIAEGTPQGKGLDIAESSPVDGFDAKFTG 62
Query: 436 STDYSITAGSKICVVTAGVRQREG 507
+ DY+ G+ + +VTAGV ++ G
Sbjct: 63 ANDYAAIEGADVVIVTAGVPRKPG 86
>UniRef50_UPI0000DB7267 Cluster: PREDICTED: similar to
Ecdysone-inducible gene L3 CG10160-PA; n=1; Apis
mellifera|Rep: PREDICTED: similar to Ecdysone-inducible
gene L3 CG10160-PA - Apis mellifera
Length = 368
Score = 68.1 bits (159), Expect = 2e-10
Identities = 26/66 (39%), Positives = 46/66 (69%)
Frame = +3
Query: 525 VQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSAR 704
V+ N V K+IIP + +++ ++L+I + P D+++Y+ WK+SG P +RV+G GT +D AR
Sbjct: 135 VKHNLKVFKKIIPAIARFAAKSVLLIVTRPADVMSYIAWKLSGFPSNRVLGIGTLIDCAR 194
Query: 705 FRYLLS 722
+ +S
Sbjct: 195 LQDFVS 200
Score = 50.4 bits (115), Expect = 4e-05
Identities = 22/73 (30%), Positives = 43/73 (58%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 441
KV+IVGVG++G+A A ++L + + + + L+D A+K E D+QH F+ + ++
Sbjct: 50 KVSIVGVGKIGIACAIAILMRRMASEVCLIDHDANKASAEAEDIQHVGFFLGCPLVTGTS 109
Query: 442 DYSITAGSKICVV 480
+ S S + ++
Sbjct: 110 EISTVKESAVVII 122
>UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=1;
Sulfurovum sp. NBC37-1|Rep: Malate dehydrogenase,
NAD-dependent - Sulfurovum sp. (strain NBC37-1)
Length = 320
Score = 67.3 bits (157), Expect = 4e-10
Identities = 28/70 (40%), Positives = 48/70 (68%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SR DL+ +N D++K ++ +Y+PD I+++ SNP+D++TYV K +G P+ RV+G
Sbjct: 90 SRDDLLFKNADIVKCYSREIKEYAPDAIVIVVSNPLDVMTYVALKETGFPRQRVLGMAGI 149
Query: 690 LDSARFRYLL 719
LD+AR + +
Sbjct: 150 LDAARMAHFI 159
Score = 39.5 bits (88), Expect = 0.083
Identities = 21/83 (25%), Positives = 41/83 (49%), Gaps = 1/83 (1%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDL-QHGSAFMRNAKIQSS 438
KVT++G G G AF + +++ L D KG+ +D+ Q +A ++ ++++
Sbjct: 6 KVTVIGTGNFGSTVAFILAMNGSCHHVMLRGRNYDVAKGKALDMSQAANAARQHTIVKAA 65
Query: 439 TDYSITAGSKICVVTAGVRQREG 507
GS + ++TAG + G
Sbjct: 66 KGPEDMEGSDVVIITAGAPRTPG 88
>UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3;
Actinomycetales|Rep: Lactate/malate dehydrogenase -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 330
Score = 67.3 bits (157), Expect = 4e-10
Identities = 25/72 (34%), Positives = 50/72 (69%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SR+DL++ N +++ + + KY+P ++++ SNP+D +T +T ++G PK+RV+G
Sbjct: 104 SRMDLLETNARIVRGVAENIAKYAPSAVVIVVSNPLDEMTALTQLVTGFPKNRVMGQAGM 163
Query: 690 LDSARFRYLLSD 725
LD+ARF + +++
Sbjct: 164 LDTARFSHFVAE 175
>UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3;
Methanomicrobiales|Rep: L-lactate dehydrogenase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 319
Score = 67.3 bits (157), Expect = 4e-10
Identities = 31/72 (43%), Positives = 47/72 (65%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RLDL N ++K Q+ + +P+ IL++ +NPVDI+T V K SG+ HRV G GT+
Sbjct: 90 TRLDLALENARIVKVFAEQVGRMAPEAILLVVTNPVDIMTTVALKYSGMMPHRVFGLGTH 149
Query: 690 LDSARFRYLLSD 725
LDS R + L++
Sbjct: 150 LDSMRLKACLAE 161
>UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex
aeolicus|Rep: Malate dehydrogenase 2 - Aquifex aeolicus
Length = 334
Score = 67.3 bits (157), Expect = 4e-10
Identities = 31/72 (43%), Positives = 46/72 (63%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SR DL+ N +LK+ + +Y+ D+I+++ SNPVD LTY T K++G RVIG
Sbjct: 105 SREDLLYENLKILKKFTDAIKEYAKDSIIIVVSNPVDTLTYATIKLTGFEPRRVIGMAGV 164
Query: 690 LDSARFRYLLSD 725
LDSARF+ + +
Sbjct: 165 LDSARFKNFVKE 176
>UniRef50_Q9CGG8 Cluster: L-lactate dehydrogenase 3; n=3;
Lactococcus lactis|Rep: L-lactate dehydrogenase 3 -
Lactococcus lactis subsp. lactis (Streptococcus lactis)
Length = 323
Score = 67.3 bits (157), Expect = 4e-10
Identities = 29/71 (40%), Positives = 50/71 (70%)
Frame = +3
Query: 513 RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNL 692
RL L++ ++++ I + + D I ++ASNPVD+L V ++SGLPKHRVIG+GT L
Sbjct: 95 RLQLLENKVEMIRDITRKTMDAGFDGIFLVASNPVDVLAQVVAEVSGLPKHRVIGTGTLL 154
Query: 693 DSARFRYLLSD 725
+++R R ++++
Sbjct: 155 ETSRMRQIVAE 165
Score = 42.7 bits (96), Expect = 0.009
Identities = 24/79 (30%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
Frame = +1
Query: 253 NWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNA-KI 429
N KV IVG G VG A +++ ++ + IA+++ K +DL H ++ A K
Sbjct: 4 NNKKVVIVGAGAVGSTYAHNLVVDDLADEIAIINTNKSKASANSLDLLHALPYLNAAPKN 63
Query: 430 QSSTDYSITAGSKICVVTA 486
+ DYS + + I V++A
Sbjct: 64 IYAADYSDVSDADIVVLSA 82
>UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2;
Planctomycetaceae|Rep: L-lactate/malate dehydrogenase -
Rhodopirellula baltica
Length = 304
Score = 66.9 bits (156), Expect = 5e-10
Identities = 33/71 (46%), Positives = 48/71 (67%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RL++ N +L+ +P L K SP+ I+V+ SNPVD L Y T +++G RVIG+GT
Sbjct: 86 TRLEMGIDNMPILRDWMPGLAKASPNAIVVMVSNPVDALAYETIRLTGFDPKRVIGTGTL 145
Query: 690 LDSARFRYLLS 722
+DS R+R LLS
Sbjct: 146 VDSIRYRALLS 156
Score = 49.6 bits (113), Expect = 8e-05
Identities = 26/78 (33%), Positives = 47/78 (60%), Gaps = 1/78 (1%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFM-RNAKIQSS 438
K+T+VG G+VG A AF++ + + + L++ +K +G+ +DL H +A + N KI SS
Sbjct: 2 KITLVGTGRVGSAIAFALTINPLASELLLLNRSREKAEGDALDLTHAAALVDSNIKI-SS 60
Query: 439 TDYSITAGSKICVVTAGV 492
+ + + S + + TA V
Sbjct: 61 GEIADSKDSDVIIFTASV 78
>UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
Lactate/malate dehydrogenase - Candidatus Nitrosopumilus
maritimus SCM1
Length = 304
Score = 66.5 bits (155), Expect = 6e-10
Identities = 25/72 (34%), Positives = 49/72 (68%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+R+DL++ N ++K ++ + KY+ D++++ +NP+D + Y+T+K+SG + RV G G
Sbjct: 85 TRMDLLKINASIVKSVVENVKKYADDSMIIPVTNPLDPMAYITYKVSGFDRSRVFGMGGM 144
Query: 690 LDSARFRYLLSD 725
LD +RFR + +
Sbjct: 145 LDLSRFRQFIHE 156
Score = 44.0 bits (99), Expect = 0.004
Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 1/82 (1%)
Frame = +1
Query: 265 VTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHG-SAFMRNAKIQSST 441
+TI+G G+VG AA + + + I L+D+ +GE MD+ H S + +++ S
Sbjct: 2 ITIIGSGKVGGDAALFSALKRLDDQILLLDVAEGLPQGEAMDINHMLSEQGIDVEVKGSN 61
Query: 442 DYSITAGSKICVVTAGVRQREG 507
++ GS I VV AG ++ G
Sbjct: 62 NFEDMKGSNIVVVVAGSGRKPG 83
>UniRef50_Q6YPG1 Cluster: Putative uncharacterized protein
OJA1212_C06.24; n=1; Oryza sativa (japonica
cultivar-group)|Rep: Putative uncharacterized protein
OJA1212_C06.24 - Oryza sativa subsp. japonica (Rice)
Length = 255
Score = 66.1 bits (154), Expect = 8e-10
Identities = 35/71 (49%), Positives = 43/71 (60%)
Frame = -3
Query: 724 SDSR*RNRAESKLVPDPMTRCLGSPLIFHVTYVRISTGLLAITNIVSGLYFISCGIICLR 545
S R RN ES+LVP+PMTR G+P FH TYV STGL I++ SG S G I
Sbjct: 47 SARRKRNLEESRLVPEPMTRLAGNPDSFHATYVSTSTGLETISSSASGECSASAGTIFRN 106
Query: 544 TSVFLCTRSRR 512
++ F C+R RR
Sbjct: 107 SATFRCSRFRR 117
Score = 40.3 bits (90), Expect = 0.047
Identities = 26/57 (45%), Positives = 29/57 (50%)
Frame = -2
Query: 509 SPSRCRTPAVTTQIFEPAVIE*SVLDWILAFLMNADPCCRSIISPFNLSAIMSTRAM 339
SP R PAVT EP V SV + NA CCRS ISP +LS ST A+
Sbjct: 119 SPGIWRAPAVTMARSEPRVTARSVSETRRTRGRNAAACCRSSISPRSLSGTASTSAI 175
>UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;
Clostridium phytofermentans ISDg|Rep: L-lactate
dehydrogenase precursor - Clostridium phytofermentans
ISDg
Length = 325
Score = 65.7 bits (153), Expect = 1e-09
Identities = 32/85 (37%), Positives = 50/85 (58%)
Frame = +1
Query: 253 NWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQ 432
N SKV +VG G VG + AFS++TQ+V + + L+D+ K GE+MDL H ++ +
Sbjct: 6 NRSKVIVVGAGLVGTSTAFSLITQSVCDEVMLIDINRAKAHGEVMDLCHSIEYLNRNVLV 65
Query: 433 SSTDYSITAGSKICVVTAGVRQREG 507
+ DY+ + I V+TAG + G
Sbjct: 66 TEGDYTDCKDADIVVITAGPPPKPG 90
Score = 63.3 bits (147), Expect = 6e-09
Identities = 26/72 (36%), Positives = 48/72 (66%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SRLD + + D++ I+ ++K + I ++ +NPVD + +++SGLPK +V+G+GT
Sbjct: 92 SRLDTLGLSADIVSTIVEPVMKSGFNGIFLVVTNPVDSIAQYVYQLSGLPKQQVLGTGTA 151
Query: 690 LDSARFRYLLSD 725
+DSAR ++ + D
Sbjct: 152 IDSARLKHFIGD 163
>UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14;
Thermoprotei|Rep: Malate dehydrogenase - Pyrobaculum
aerophilum
Length = 309
Score = 65.7 bits (153), Expect = 1e-09
Identities = 26/68 (38%), Positives = 46/68 (67%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+R L++ N ++ +I ++ KY+PD+I+++ +NP+D +TYV WK +G P+ RVIG
Sbjct: 85 TREQLLEANAKIVAEIGREIKKYAPDSIVILTTNPLDAMTYVMWKATGFPRERVIGFSGV 144
Query: 690 LDSARFRY 713
LD+ R +
Sbjct: 145 LDAGRLAF 152
Score = 55.2 bits (127), Expect = 2e-06
Identities = 28/82 (34%), Positives = 48/82 (58%), Gaps = 1/82 (1%)
Frame = +1
Query: 265 VTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFM-RNAKIQSST 441
+TI+G G+VG AAA M + N I L+D++ +GE +D+ H S+ + + + S
Sbjct: 2 ITIIGSGRVGTAAAVIMGLMKLDNKILLIDIVKGLPQGEALDMNHMSSILGLDVEYVGSN 61
Query: 442 DYSITAGSKICVVTAGVRQREG 507
+Y GS + +VTAG+ ++ G
Sbjct: 62 EYKDIEGSDLIIVTAGLPRKPG 83
>UniRef50_A7I2F1 Cluster: Malate dehydrogenase; n=1; Campylobacter
hominis ATCC BAA-381|Rep: Malate dehydrogenase -
Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 /
NCTC 13146 /CH001A)
Length = 297
Score = 64.9 bits (151), Expect = 2e-09
Identities = 27/68 (39%), Positives = 41/68 (60%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SR DL+ N ++ + KY+P+ I+++ +NPVD L +V +K SG K ++I
Sbjct: 87 SRADLLNDNAKIISSCAKNVAKYAPEAIIILITNPVDTLAFVAYKASGFKKEKIIAMAGE 146
Query: 690 LDSARFRY 713
LDSAR RY
Sbjct: 147 LDSARLRY 154
Score = 51.6 bits (118), Expect = 2e-05
Identities = 26/84 (30%), Positives = 46/84 (54%), Gaps = 2/84 (2%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVT-NNIALVDMMADKLKGEMMDLQH-GSAFMRNAKIQS 435
K++I+G G +G +L ++ + IAL+D+ D K +DL H S + + +I
Sbjct: 2 KISIIGAGNIGSNIVSQLLCKDFEISQIALIDIFGDLAKARALDLSHLASVYNKKTEISG 61
Query: 436 STDYSITAGSKICVVTAGVRQREG 507
S+D ++ S I V+TAG ++ G
Sbjct: 62 SSDETLLKNSDIVVITAGKTRQAG 85
>UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4;
Bacteria|Rep: L-lactate dehydrogenase - Blastopirellula
marina DSM 3645
Length = 313
Score = 64.5 bits (150), Expect = 3e-09
Identities = 34/73 (46%), Positives = 44/73 (60%), Gaps = 2/73 (2%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIK--YSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSG 683
SRLDL+ RN D+ I+ + D I + SNPVDILTY+ + LP RVIG G
Sbjct: 85 SRLDLINRNVDLFLSILDSVKSAGVKKDAICFVVSNPVDILTYLAAQRLNLPTSRVIGLG 144
Query: 684 TNLDSARFRYLLS 722
T LD+ RFR L++
Sbjct: 145 TQLDTIRFRALIA 157
Score = 50.4 bits (115), Expect = 4e-05
Identities = 31/99 (31%), Positives = 55/99 (55%), Gaps = 2/99 (2%)
Frame = +1
Query: 262 KVTIVGVGQ-VGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 438
KV+I+G G VG AAF++ + IAL+D+ AD G +DL HG+ + + ++ +S
Sbjct: 2 KVSIIGGGGLVGSCAAFALQCGGIAREIALLDLNADLAGGHALDLLHGAPSVAD-QVITS 60
Query: 439 TDYSITAGSKICVVTAGVRQR-EGDLVSISCRETPMFLN 552
Y S + +TAG+R++ + + + R +FL+
Sbjct: 61 GGYEHIPDSDVICITAGLRRKPDESRLDLINRNVDLFLS 99
>UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD binding
domain protein; n=2; Campylobacter|Rep: Lactate/malate
dehydrogenase, NAD binding domain protein -
Campylobacter curvus 525.92
Length = 297
Score = 63.7 bits (148), Expect = 4e-09
Identities = 27/68 (39%), Positives = 44/68 (64%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+R DL+ +N V+KQ + K++P+ I++I +NP+D++ + + SG + RVIG
Sbjct: 86 TREDLLLKNAQVVKQTAQNIAKFAPNAIVIIVTNPLDVMVWTVLRYSGFDRSRVIGMAGE 145
Query: 690 LDSARFRY 713
LDSAR RY
Sbjct: 146 LDSARCRY 153
Score = 55.6 bits (128), Expect = 1e-06
Identities = 27/83 (32%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDL-QHGSAFMRNAKIQSS 438
K++++G G VG + A+++ + V + IALVD+ D + + +D+ Q G F
Sbjct: 2 KISVIGAGNVGASIAYALAMRGVCDEIALVDIFGDVARAKAIDIAQAGCVFCGCLSTAGG 61
Query: 439 TDYSITAGSKICVVTAGVRQREG 507
D+++ S I VVTAG ++EG
Sbjct: 62 DDFALIEASDIVVVTAGSPRKEG 84
>UniRef50_A3ZZ88 Cluster: L-lactate/malate dehydrogenase; n=1;
Blastopirellula marina DSM 3645|Rep: L-lactate/malate
dehydrogenase - Blastopirellula marina DSM 3645
Length = 308
Score = 63.7 bits (148), Expect = 4e-09
Identities = 30/64 (46%), Positives = 43/64 (67%)
Frame = +3
Query: 534 NTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRY 713
N + L++ IP L SP I V+ +NPVD++T+ ++SG P+ RV G GT LD+AR R
Sbjct: 94 NLERLRERIPILAAASPQAICVMVTNPVDVMTWFALQLSGFPQERVFGVGTLLDTARLRR 153
Query: 714 LLSD 725
LLS+
Sbjct: 154 LLSE 157
Score = 41.5 bits (93), Expect = 0.021
Identities = 20/85 (23%), Positives = 46/85 (54%), Gaps = 1/85 (1%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNA-KIQSS 438
KV+++G+G+VG A A +++ + + + + LV + + E DL H + ++ ++++
Sbjct: 2 KVSLIGLGKVGSAVAHAIVLKGLADELVLVSRRTEMARSEADDLNHAAGLEEHSVEVRAG 61
Query: 439 TDYSITAGSKICVVTAGVRQREGDL 513
D TAGS + + + + D+
Sbjct: 62 GDVD-TAGSDVILYCDAAQSKTSDV 85
>UniRef50_A7DSJ4 Cluster: Lactate/malate dehydrogenase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
Lactate/malate dehydrogenase - Candidatus Nitrosopumilus
maritimus SCM1
Length = 303
Score = 63.3 bits (147), Expect = 6e-09
Identities = 26/71 (36%), Positives = 46/71 (64%)
Frame = +3
Query: 513 RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNL 692
R + + ++K I ++ KY P I+++ SNP+D+LTY K +G + +VIG ++L
Sbjct: 86 RAENIDHQVAMIKNIAKKIKKYCPSAIVLLVSNPLDVLTYFFQKTTGFSRFKVIGIASSL 145
Query: 693 DSARFRYLLSD 725
D++RFRY +S+
Sbjct: 146 DTSRFRYYISE 156
>UniRef50_P59050 Cluster: L-lactate dehydrogenase 1; n=3;
Bifidobacterium longum|Rep: L-lactate dehydrogenase 1 -
Bifidobacterium longum
Length = 316
Score = 63.3 bits (147), Expect = 6e-09
Identities = 34/80 (42%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Frame = +1
Query: 253 NWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFM-RNAKI 429
N +KV IVG GQVG AAF ++T + N + L+D A K GE DL GS F R+ K+
Sbjct: 5 NRNKVVIVGTGQVGATAAFGIVTHGLCNELVLIDCSAAKALGEARDLDDGSEFQDRHVKV 64
Query: 430 QSSTDYSITAGSKICVVTAG 489
++ DY+ + I V+T G
Sbjct: 65 RAG-DYADCKDADIVVITVG 83
Score = 56.0 bits (129), Expect = 9e-07
Identities = 20/58 (34%), Positives = 41/58 (70%)
Frame = +3
Query: 552 QIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSD 725
+++ ++ D ++V+ SNPVD++ + WK SGLP+ +V+G+GT LD++R + ++ +
Sbjct: 105 EVVDNVMASGFDGVIVMVSNPVDVMAWYAWKRSGLPRTQVLGTGTALDTSRLKTIIGE 162
>UniRef50_UPI000038D9FF Cluster: COG0039: Malate/lactate
dehydrogenases; n=2; Nostoc punctiforme PCC 73102|Rep:
COG0039: Malate/lactate dehydrogenases - Nostoc
punctiforme PCC 73102
Length = 317
Score = 62.9 bits (146), Expect = 8e-09
Identities = 28/70 (40%), Positives = 47/70 (67%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RLD + N ++++ I +L + +P++I++I SNPVD+LT + S ++ + GSGT
Sbjct: 91 TRLDTLSDNAEIIRSTIKELDRVAPNSIVIIISNPVDVLTRIAQATSTRAENLIFGSGTV 150
Query: 690 LDSARFRYLL 719
LD+AR RY L
Sbjct: 151 LDTARLRYQL 160
Score = 44.4 bits (100), Expect = 0.003
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 438
SKV I+G G VG A +++ + L D K +G++ D++ ++ +I S
Sbjct: 6 SKVGIIGAGNVGADVANALVLLGRCVRVVLFDRTLSKAEGQVWDIEDSIPLLKEMEIIPS 65
Query: 439 TDYSITAGSK-ICVVTAGVRQREG 507
Y A S I +VTAGV+ + G
Sbjct: 66 NQYEDLADSDIIIIVTAGVQPKLG 89
>UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1;
Cenarchaeum symbiosum|Rep: Malate/L-lactate
dehydrogenase - Cenarchaeum symbiosum
Length = 302
Score = 62.5 bits (145), Expect = 1e-08
Identities = 24/72 (33%), Positives = 50/72 (69%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+R+DL++ N ++K ++ ++ +++ D++++ +NP+D +TY+ +K SG K+RV G G
Sbjct: 85 TRMDLLKINAGIVKGVVEKVKEHAKDSMIIPVTNPLDPITYIAYKTSGFEKNRVFGMGGM 144
Query: 690 LDSARFRYLLSD 725
LD +RFR + +
Sbjct: 145 LDLSRFRQFIHE 156
Score = 52.4 bits (120), Expect = 1e-05
Identities = 29/82 (35%), Positives = 46/82 (56%), Gaps = 1/82 (1%)
Frame = +1
Query: 265 VTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMR-NAKIQSST 441
+TI+G G+VG AA + + + I L+D++ +GE MD+ H A + +++ S
Sbjct: 2 ITIIGAGKVGGDAAMFCALRRLDSEILLLDIVEGLPQGEAMDINHMLAEQGIDTEVRGSN 61
Query: 442 DYSITAGSKICVVTAGVRQREG 507
DYS GS I VV AG ++ G
Sbjct: 62 DYSDMEGSDIVVVVAGAGRKPG 83
>UniRef50_UPI000023CE12 Cluster: hypothetical protein FG10444.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG10444.1 - Gibberella zeae PH-1
Length = 309
Score = 61.7 bits (143), Expect = 2e-08
Identities = 26/69 (37%), Positives = 48/69 (69%)
Frame = +3
Query: 516 LDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLD 695
+D RNT +L+ ++ + + DT+L+I ++PVD+LT + ++SGLP+ +V G+GT LD
Sbjct: 91 IDYTSRNTSMLRGVMEAMKPFRADTVLLIVADPVDLLTSLAKQMSGLPESQVFGTGTALD 150
Query: 696 SARFRYLLS 722
+ R R +++
Sbjct: 151 TYRLRGMIA 159
Score = 42.3 bits (95), Expect = 0.012
Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 438
S+V IVGVG+VG A A+++ ++ + + LVD+ ++ DL + ++ S
Sbjct: 5 SRVAIVGVGEVGGAVAYNLTLNSMASELLLVDLDPSARNAQIEDLSDVTYSTNSSTRVRS 64
Query: 439 TDYSITAGSKICVVTAGVRQREGD-LVSISCRETPM 543
Y A + V+TA + G + + R T M
Sbjct: 65 ATYHEAAQCDLVVITAASKHMLGQTTIDYTSRNTSM 100
>UniRef50_A4BB89 Cluster: Lactate dehydrogenase; n=2;
Gammaproteobacteria|Rep: Lactate dehydrogenase -
Reinekea sp. MED297
Length = 319
Score = 61.7 bits (143), Expect = 2e-08
Identities = 32/98 (32%), Positives = 53/98 (54%), Gaps = 6/98 (6%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSA--FMRNAKIQS 435
K+ ++G G VG+ L + + L+D K +GEMMD H ++ F +N ++++
Sbjct: 2 KIGVIGAGAVGVGVCHYTLAFGSCSELVLIDQQIGKAEGEMMDFGHANSLTFSKNIRLRA 61
Query: 436 STDYSITAGSKICVVTAGVRQREG----DLVSISCRET 537
DYS+ + I V+TAG + +EG DL I+ R T
Sbjct: 62 GDDYSLLTDADIVVITAGAQIKEGQTRDDLAEINSRIT 99
Score = 52.0 bits (119), Expect = 1e-05
Identities = 25/72 (34%), Positives = 43/72 (59%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+R DL + N+ + I ++ +P+ IL++ +NP DI TY + +G P RVI +G
Sbjct: 87 TRDDLAEINSRITVDIAQKIETVAPNAILLVVTNPCDIATYFITQNTGFPADRVISAGCI 146
Query: 690 LDSARFRYLLSD 725
+D+AR L+S+
Sbjct: 147 IDTARLMKLVSE 158
>UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6;
Mollicutes|Rep: L-lactate dehydrogenase - Mesoplasma
florum (Acholeplasma florum)
Length = 317
Score = 61.7 bits (143), Expect = 2e-08
Identities = 29/72 (40%), Positives = 48/72 (66%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RL+L+ N+ ++K I + + + VIASNP D+LT V +++G +H V+G+GT
Sbjct: 90 TRLELIADNSRIMKGIAEAIKASGFNGVTVIASNPCDVLTTVYQQVTGYDEHSVVGAGTT 149
Query: 690 LDSARFRYLLSD 725
LDSAR R L+++
Sbjct: 150 LDSARLRRLVAE 161
Score = 46.8 bits (106), Expect = 5e-04
Identities = 24/84 (28%), Positives = 41/84 (48%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 438
+KV +VG G VGM+ +S + Q + L+D+ +G +D+Q A + +
Sbjct: 6 NKVVLVGTGAVGMSFIYSAVNQGLAEEYVLIDVNTKAAEGNAIDIQDTMAVLDKPFTIKA 65
Query: 439 TDYSITAGSKICVVTAGVRQREGD 510
Y + + V+TAG QR G+
Sbjct: 66 GTYEDCKDADLIVITAGRPQRPGE 89
>UniRef50_Q97DC6 Cluster: L-lactate dehydrogenase 2; n=1;
Clostridium acetobutylicum|Rep: L-lactate dehydrogenase
2 - Clostridium acetobutylicum
Length = 320
Score = 61.7 bits (143), Expect = 2e-08
Identities = 28/69 (40%), Positives = 42/69 (60%)
Frame = +3
Query: 513 RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNL 692
RL L N V I+ + KY+ D I+++ +NPVDI TY PK+++IG+GT L
Sbjct: 94 RLVLADTNVKVTDSIMKNICKYTKDAIIIVVTNPVDIATYYCQNNFDYPKNKIIGTGTLL 153
Query: 693 DSARFRYLL 719
D+AR R ++
Sbjct: 154 DTARMRKII 162
Score = 54.8 bits (126), Expect = 2e-06
Identities = 28/86 (32%), Positives = 51/86 (59%), Gaps = 2/86 (2%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGS--AFMRNAKIQ 432
+K+ +VG G VG A S+L+ N+ + + ++D+ +K KGE +D H + A+ N K++
Sbjct: 6 NKLVVVGAGMVGSAVLNSVLSLNLLSEVVIIDINDNKAKGEALDASHTTSFAYSPNVKVR 65
Query: 433 SSTDYSITAGSKICVVTAGVRQREGD 510
+ +Y A ++I V+TAG + D
Sbjct: 66 AG-NYEDCADAQIIVITAGPSLKPDD 90
>UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
pulmonis|Rep: L-lactate dehydrogenase - Mycoplasma
pulmonis
Length = 315
Score = 61.3 bits (142), Expect = 2e-08
Identities = 28/72 (38%), Positives = 47/72 (65%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RL+++ N+ ++K I ++ K + ++ SNPVDIL V K++ PK +V+ SGT
Sbjct: 87 TRLEMIADNSKIMKDIALEIKKSGFNGFTIVISNPVDILATVFQKVTNFPKEKVMSSGTF 146
Query: 690 LDSARFRYLLSD 725
LD++RFR LS+
Sbjct: 147 LDTSRFRKFLSE 158
Score = 51.6 bits (118), Expect = 2e-05
Identities = 25/85 (29%), Positives = 47/85 (55%), Gaps = 2/85 (2%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAF--MRNAKIQS 435
KV ++G G VG+ ++M+T+ + L+D+ + KG MD+ A +KI++
Sbjct: 3 KVVLIGTGNVGVTVVYTMITKGIDAEYVLIDINTEFAKGHAMDMSDAIALNSTTGSKIRT 62
Query: 436 STDYSITAGSKICVVTAGVRQREGD 510
T Y+ G+ + +V AG Q++G+
Sbjct: 63 GT-YADAKGADLLIVAAGRPQKQGE 86
>UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1;
Lactobacillus casei ATCC 334|Rep: L-lactate
dehydrogenase - Lactobacillus casei (strain ATCC 334)
Length = 312
Score = 60.9 bits (141), Expect = 3e-08
Identities = 28/67 (41%), Positives = 46/67 (68%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RL L+ N ++K+I ++ + +++ASNPVD+L + + SGLP+++V+GSGT
Sbjct: 88 TRLQLLAINAKIMKEITHNIMASGFNGFILVASNPVDVLAELVLQESGLPRNQVLGSGTA 147
Query: 690 LDSARFR 710
LDSAR R
Sbjct: 148 LDSARLR 154
>UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular
organisms|Rep: Malate dehydrogenase - Gloeobacter
violaceus
Length = 325
Score = 60.1 bits (139), Expect = 5e-08
Identities = 25/71 (35%), Positives = 46/71 (64%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SR DL+ NT ++ ++ + + +SP+ +V+ +NP+D +++V W+ SGL RV+G
Sbjct: 93 SRDDLLLTNTRIVFEVTQKAVAHSPEATVVVVTNPLDAMSHVAWRASGLVPERVMGMAGV 152
Query: 690 LDSARFRYLLS 722
LD+ARF ++
Sbjct: 153 LDAARFETFIA 163
Score = 50.4 bits (115), Expect = 4e-05
Identities = 29/84 (34%), Positives = 47/84 (55%), Gaps = 1/84 (1%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFM-RNAKIQS 435
SKV+I+G G VG A A ++ NV + + L+D++ + +G +DL +I
Sbjct: 9 SKVSILGAGNVGSALAQRLIQGNVAD-VVLLDIVEGRPQGITLDLLEACGVEGHTCRITG 67
Query: 436 STDYSITAGSKICVVTAGVRQREG 507
+ DY+ TAGS + VV AG ++ G
Sbjct: 68 TNDYAQTAGSDVLVVAAGFARQPG 91
>UniRef50_Q0PQR8 Cluster: Malate dehydrogenase NAD-dependent; n=1;
Endoriftia persephone 'Hot96_1+Hot96_2'|Rep: Malate
dehydrogenase NAD-dependent - Endoriftia persephone
'Hot96_1+Hot96_2'
Length = 170
Score = 59.7 bits (138), Expect = 7e-08
Identities = 25/64 (39%), Positives = 41/64 (64%)
Frame = +3
Query: 519 DLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDS 698
DL+ N V K++ + +++PD +++ +NP+D + Y K+SGLP R+IG LD+
Sbjct: 17 DLLDINLSVTKKVATAVKQHAPDAFVILTTNPLDSIVYAFHKLSGLPAERIIGMAGALDT 76
Query: 699 ARFR 710
ARFR
Sbjct: 77 ARFR 80
>UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2;
Theileria|Rep: L-lactate dehydrogenase, putative -
Theileria annulata
Length = 367
Score = 59.7 bits (138), Expect = 7e-08
Identities = 22/72 (30%), Positives = 48/72 (66%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+R DLV N+ +++ + + KY+P+ +++ +NP+D++ ++ K++G PK+ V+G G
Sbjct: 142 NRDDLVGYNSKIIRDVGENIKKYAPEAFVIVITNPMDVMVHLMLKVTGFPKNMVVGMGGL 201
Query: 690 LDSARFRYLLSD 725
LDS+R +++
Sbjct: 202 LDSSRMNCYIAE 213
Score = 39.1 bits (87), Expect = 0.11
Identities = 22/89 (24%), Positives = 46/89 (51%), Gaps = 2/89 (2%)
Frame = +1
Query: 265 VTIVGVGQVGMAAAFSMLTQ-NVTNNIALVDMMADKLKGEMMDLQHGSAFMRNA-KIQSS 438
++++G G +G + LTQ ++ D++ + G+ +D+ H ++ A K + +
Sbjct: 10 ISLIGSGNIGGIMGY--LTQLTELADVNFFDIVPNIGAGKSLDIMHANSIQGKAYKCKGT 67
Query: 439 TDYSITAGSKICVVTAGVRQREGDLVSIS 525
+Y +GS +C+VTAG E + I+
Sbjct: 68 NNYEDISGSDVCIVTAGNSYEENNSTKIA 96
>UniRef50_Q2FPC3 Cluster: Lactate/malate dehydrogenase; n=2;
Methanomicrobiales|Rep: Lactate/malate dehydrogenase -
Methanospirillum hungatei (strain JF-1 / DSM 864)
Length = 290
Score = 59.7 bits (138), Expect = 7e-08
Identities = 30/71 (42%), Positives = 43/71 (60%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+R L+ N V ++ + Y I+++ +NP DILTY WK G+ K+R+IG G
Sbjct: 82 TRAALLDCNVPVASELATLIPDYKG--IIIVVTNPADILTYYLWKSLGILKNRIIGFGGQ 139
Query: 690 LDSARFRYLLS 722
LDSARF+Y LS
Sbjct: 140 LDSARFQYELS 150
>UniRef50_O26290 Cluster: Malate dehydrogenase; n=2;
Methanobacteriaceae|Rep: Malate dehydrogenase -
Methanobacterium thermoautotrophicum
Length = 325
Score = 59.3 bits (137), Expect = 1e-07
Identities = 25/66 (37%), Positives = 42/66 (63%)
Frame = +3
Query: 513 RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNL 692
R DL +N ++ Q+ +++PD+I+++ +NPVD++TYV + SG RV G G +L
Sbjct: 90 RDDLAFKNGRIVADYARQIARFAPDSIILVVTNPVDVMTYVALRYSGFHPSRVFGLGNHL 149
Query: 693 DSARFR 710
DS R +
Sbjct: 150 DSLRLK 155
Score = 39.9 bits (89), Expect = 0.063
Identities = 25/81 (30%), Positives = 43/81 (53%), Gaps = 4/81 (4%)
Frame = +1
Query: 262 KVTIVG-VGQVGMAAAFSMLTQNVTNNIALVDMMA--DKLKGEMMDLQHGSAFMR-NAKI 429
KV+I+G G+VG A A + + + L+ ++ GE++D+ A + K+
Sbjct: 2 KVSIIGSTGRVGRATALCLAEEEAVKTLHLISRKESLEQNLGEVLDMSDALAAKGVSVKL 61
Query: 430 QSSTDYSITAGSKICVVTAGV 492
++S D GS+I V+TAGV
Sbjct: 62 ENSADIENVYGSRIVVITAGV 82
>UniRef50_Q4A0K7 Cluster: Lactate dehydrogenase; n=1; Staphylococcus
saprophyticus subsp. saprophyticus ATCC 15305|Rep:
Lactate dehydrogenase - Staphylococcus saprophyticus
subsp. saprophyticus (strain ATCC 15305 /DSM 20229)
Length = 310
Score = 58.8 bits (136), Expect = 1e-07
Identities = 24/68 (35%), Positives = 47/68 (69%)
Frame = +3
Query: 522 LVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSA 701
L Q N D++K I+ Q+ + + + ++++ SNPVD + Y +I P H++IG+GT L+++
Sbjct: 92 LAQGNHDIIKGIMSQIAEVTQEAVVILISNPVDSMVYFANQID-YPAHKIIGTGTALETS 150
Query: 702 RFRYLLSD 725
RF+ +++D
Sbjct: 151 RFKTIIAD 158
Score = 38.7 bits (86), Expect = 0.14
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 2/78 (2%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNA--KIQ 432
SK+ I+G+G+VG + N+ + I L+D AD GE +D H + A KI+
Sbjct: 2 SKLGIIGLGKVGTQVLTDVQQLNLFSEIILIDDRADVASGEALDHIHSQGLINTAHIKIR 61
Query: 433 SSTDYSITAGSKICVVTA 486
S +T I + +
Sbjct: 62 SGVYQDLTDADFIVIAAS 79
>UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
mobile|Rep: L-lactate dehydrogenase - Mycoplasma mobile
Length = 318
Score = 58.8 bits (136), Expect = 1e-07
Identities = 26/71 (36%), Positives = 45/71 (63%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RL++V N ++ I + K + ++ +NPVD++T++ +G K+RVI SGT+
Sbjct: 90 TRLEMVADNAKIMSNIAKNIKKSGFKGVSIVVANPVDVMTFIYQHETGFDKNRVISSGTS 149
Query: 690 LDSARFRYLLS 722
LDSAR R+ +S
Sbjct: 150 LDSARLRFEIS 160
Score = 40.3 bits (90), Expect = 0.047
Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLK-GEMMDLQHGSAFMRNAKIQSS 438
+V +VG G VG++ +S + + + ++D + DKL G +D + SA +
Sbjct: 7 RVAMVGAGLVGVSVLYSCMNRGLAEQYGIID-INDKLSVGHSLDFEDASAANNHNFSVGK 65
Query: 439 TDYSITAGSKICVVTAGVRQREGD 510
+YS + V+TAG Q+ G+
Sbjct: 66 IEYSDLKDYDVVVITAGRPQKPGE 89
>UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;
Candidatus Methanoregula boonei 6A8|Rep: L-lactate
dehydrogenase precursor - Methanoregula boonei (strain
6A8)
Length = 332
Score = 58.4 bits (135), Expect = 2e-07
Identities = 27/71 (38%), Positives = 45/71 (63%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RLDL N ++ + + +PDT +++ +NPVD++T V K SGL ++V G GT+
Sbjct: 90 NRLDLALGNARIIAPMARTIGTIAPDTKIIMVTNPVDVMTCVALKYSGLKPNQVFGLGTH 149
Query: 690 LDSARFRYLLS 722
LDS R + L++
Sbjct: 150 LDSMRLKSLIA 160
Score = 35.5 bits (78), Expect = 1.3
Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 4/87 (4%)
Frame = +1
Query: 259 SKVTIVGV-GQVGMAAAFSMLTQNVTNNIALVDMMADK--LKGEMMDLQHGSAFM-RNAK 426
SKVTI+G G VG AA+++ + I L + LKG D A N +
Sbjct: 2 SKVTIIGATGNVGTFAAYAVSVDPHVHEILLYGREGREAFLKGLAQDFADSFAARGTNIR 61
Query: 427 IQSSTDYSITAGSKICVVTAGVRQREG 507
+ +T AGS I V+TAG + G
Sbjct: 62 VTWTTSLKDVAGSDIVVITAGTPRGPG 88
>UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5;
Gammaproteobacteria|Rep: Malate dehydrogenase -
Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
Length = 311
Score = 58.0 bits (134), Expect = 2e-07
Identities = 24/65 (36%), Positives = 42/65 (64%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SR D++ N ++ I+ +++++P ++++I +NPVD+LTY W+ G + RV G
Sbjct: 89 SRSDVLDSNLPIITDIMNNVMRFAPQSLVMIVTNPVDVLTYHAWRHCGWDRARVFGQAGV 148
Query: 690 LDSAR 704
LDSAR
Sbjct: 149 LDSAR 153
Score = 53.6 bits (123), Expect = 5e-06
Identities = 27/83 (32%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGS-AFMRNAKIQSS 438
K+TIVG G+VG A A ++ + + L+D +G +D+Q + F +A++ S
Sbjct: 5 KITIVGAGRVGEATAQFLVKNELCRELVLLDAQEGVAQGAALDIQQSAPLFDFDARVTGS 64
Query: 439 TDYSITAGSKICVVTAGVRQREG 507
T+Y + A S + V+TAG ++ G
Sbjct: 65 TNYELIADSDLVVITAGKPRKPG 87
>UniRef50_A2UB98 Cluster: Lactate/malate dehydrogenase precursor;
n=2; Bacteria|Rep: Lactate/malate dehydrogenase
precursor - Bacillus coagulans 36D1
Length = 327
Score = 57.6 bits (133), Expect = 3e-07
Identities = 23/71 (32%), Positives = 44/71 (61%)
Frame = +3
Query: 513 RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNL 692
R L + N V+++++ + KY+ + +++ +NP+D + Y+ G K R+ G+GT L
Sbjct: 95 RAGLARTNAAVVREVMAGITKYTKEAVIIFITNPLDTIVYIAENEFGYSKGRIFGTGTML 154
Query: 693 DSARFRYLLSD 725
DSAR R L+++
Sbjct: 155 DSARLRQLVAE 165
>UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 312
Score = 57.2 bits (132), Expect = 4e-07
Identities = 26/72 (36%), Positives = 45/72 (62%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RLD++ + + ++ I+ L K I++ +NP DI+ K +GLPK+RV +GT+
Sbjct: 89 TRLDVLDGSVECVRDIVSNLNKIEIKGIIITITNPADIIADFVRKATGLPKNRVFSTGTS 148
Query: 690 LDSARFRYLLSD 725
LD+AR R ++D
Sbjct: 149 LDTARMRRTVAD 160
Score = 53.2 bits (122), Expect = 6e-06
Identities = 27/82 (32%), Positives = 42/82 (51%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 441
K+ I+G G VG A+++ Q + + I LVD K K MD+ +F ++ I
Sbjct: 6 KIVIIGAGHVGSHCAYALAIQGICDEIVLVDKDRTKAKSHSMDIADSVSFFNSSVIVRCG 65
Query: 442 DYSITAGSKICVVTAGVRQREG 507
DYS + I V++AGV + G
Sbjct: 66 DYSDCKDADIIVISAGVPRLPG 87
>UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2;
Toxoplasma gondii|Rep: Mitochondrial
malate-dehydrogenase - Toxoplasma gondii
Length = 470
Score = 57.2 bits (132), Expect = 4e-07
Identities = 26/72 (36%), Positives = 43/72 (59%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SR DL+ N ++ Q+ + +Y P+ ++ +NP+D++ Y+ + GLP H+V G
Sbjct: 242 SRDDLLAINAKIMGQVGEAIKQYCPNAFVICITNPLDVMVYILREKCGLPPHKVCGMAGV 301
Query: 690 LDSARFRYLLSD 725
LDSAR R LS+
Sbjct: 302 LDSARLRTFLSE 313
Score = 41.5 bits (93), Expect = 0.021
Identities = 23/95 (24%), Positives = 51/95 (53%), Gaps = 5/95 (5%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMR-NAKIQSS 438
K+ ++G G +G A + + ++ + D++ D +G+ +DL + + + + S
Sbjct: 159 KIGLIGGGNIGATLALLSAVKEL-GDVVMFDVVQDLPQGKCLDLYQLTPISGVDVRFEGS 217
Query: 439 TDYSITAGSKICVVTAGVRQREG----DLVSISCR 531
DYS+ + + +VTAGV ++ G DL++I+ +
Sbjct: 218 NDYSVLKDADVIIVTAGVPRKPGMSRDDLLAINAK 252
>UniRef50_Q6LZI3 Cluster: Malate dehydrogenase; n=5;
Methanococcus|Rep: Malate dehydrogenase - Methanococcus
maripaludis
Length = 314
Score = 57.2 bits (132), Expect = 4e-07
Identities = 27/67 (40%), Positives = 43/67 (64%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SR+DL++ N ++K + + + DT + + SNPVD++TY SG K++V G GT+
Sbjct: 91 SRIDLMKGNAKIVKNYVKNIANFG-DTKIFMISNPVDLMTYKALIESGYEKNQVFGLGTH 149
Query: 690 LDSARFR 710
LDS RF+
Sbjct: 150 LDSMRFK 156
>UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7;
Halobacteriaceae|Rep: Malate dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 304
Score = 56.8 bits (131), Expect = 5e-07
Identities = 28/72 (38%), Positives = 44/72 (61%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+R+DL N +++ I L +++ D I + SNPVD+L ++ + +VIG G
Sbjct: 88 TRIDLAGDNAPIMEDIQSSLDEHNDDYISLTTSNPVDLLNRHLYEAGDRSREQVIGFGGR 147
Query: 690 LDSARFRYLLSD 725
LDSARFRY+LS+
Sbjct: 148 LDSARFRYVLSE 159
Score = 54.4 bits (125), Expect = 3e-06
Identities = 28/86 (32%), Positives = 50/86 (58%), Gaps = 3/86 (3%)
Frame = +1
Query: 259 SKVTIVGV-GQVGMAAAFSMLTQNVTNNIALVDM--MADKLKGEMMDLQHGSAFMRNAKI 429
+KV++VG G VG AA +++ +++ + + VD+ D G+ D HG A+ N ++
Sbjct: 2 TKVSVVGAAGTVGAAAGYNIALRDIADEVVFVDIPDKEDDTVGQAADTNHGIAYDSNTRV 61
Query: 430 QSSTDYSITAGSKICVVTAGVRQREG 507
+ Y TAGS + V+TAG+ ++ G
Sbjct: 62 RQG-GYEDTAGSDVVVITAGIPRQPG 86
>UniRef50_Q87JV1 Cluster: Lactate dehydrogenase; n=4; Vibrio|Rep:
Lactate dehydrogenase - Vibrio parahaemolyticus
Length = 317
Score = 56.4 bits (130), Expect = 7e-07
Identities = 27/84 (32%), Positives = 48/84 (57%), Gaps = 2/84 (2%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSA--FMRNAKIQS 435
K+ ++G G VG+ +LT + + L+D ++ +GE+ D +H +A F +N +I
Sbjct: 2 KIGVIGAGAVGVGVCNYLLTLGSVSELVLLDQNLERAEGEVFDFRHTAALTFSKNTRIIP 61
Query: 436 STDYSITAGSKICVVTAGVRQREG 507
S DY G+ I V+TAG + ++G
Sbjct: 62 SDDYLDLLGADIVVITAGAQIQQG 85
Score = 46.8 bits (106), Expect = 5e-04
Identities = 20/72 (27%), Positives = 43/72 (59%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RLD+ + N + +I ++ + +P +L++ SNP DI+ + +G ++VI SG
Sbjct: 87 TRLDIAEINAKIGVEIARKIERVAPKAVLIVVSNPCDIVAHFITTNTGFEPNKVISSGCV 146
Query: 690 LDSARFRYLLSD 725
+D+AR ++++
Sbjct: 147 IDTARLMSIVAN 158
>UniRef50_Q0P989 Cluster: L-lactate dehydrogenase; n=10;
Campylobacter|Rep: L-lactate dehydrogenase -
Campylobacter jejuni
Length = 308
Score = 56.4 bits (130), Expect = 7e-07
Identities = 31/71 (43%), Positives = 44/71 (61%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SRL ++ N LK I+ L + ++A+NP D +TY T +S LPK+ V GSGTN
Sbjct: 88 SRLVELKNNILELKDIVLTLKNANFKGKYIVATNPNDTITYYTQVLSQLPKNHVFGSGTN 147
Query: 690 LDSARFRYLLS 722
LDS+R + LL+
Sbjct: 148 LDSSRLKKLLA 158
Score = 37.9 bits (84), Expect = 0.25
Identities = 18/50 (36%), Positives = 30/50 (60%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSA 408
+K+ IVG+G VG A+A+S++ Q + + + L D+ D DL+ SA
Sbjct: 2 AKIGIVGLGYVGAASAYSIVIQGICSELYLYDIKQDLALAHARDLEDMSA 51
>UniRef50_Q9EVR0 Cluster: L-lactate dehydrogenase; n=1; Selenomonas
ruminantium|Rep: L-lactate dehydrogenase - Selenomonas
ruminantium
Length = 318
Score = 55.6 bits (128), Expect = 1e-06
Identities = 21/71 (29%), Positives = 46/71 (64%)
Frame = +3
Query: 513 RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNL 692
RL L N ++ ++ +++K + + ++++ +NP+D+ TYV P++ ++G+GT L
Sbjct: 93 RLKLAGTNAKIMSSVMGEIVKRTKEAMIIMITNPLDVATYVVSTQFDYPRNLILGTGTML 152
Query: 693 DSARFRYLLSD 725
++ RFR +L+D
Sbjct: 153 ETYRFRRILAD 163
Score = 46.4 bits (105), Expect = 7e-04
Identities = 25/87 (28%), Positives = 41/87 (47%), Gaps = 1/87 (1%)
Frame = +1
Query: 253 NWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQ 432
N K+ ++G VG A A + + + L+D+ DK GE D H ++ + + I+
Sbjct: 3 NRRKIVVIGASNVGSAVANKIADFQLATEVVLIDLNEDKAWGEAKDSSHATSCIYSTNIK 62
Query: 433 SST-DYSITAGSKICVVTAGVRQREGD 510
DY + I V+TAG R G+
Sbjct: 63 FHLGDYEDCKDANIIVITAGPSIRPGE 89
>UniRef50_Q03ZZ4 Cluster: Enzyme with possible activities of L-2-
hydroxyisocaproate/malate/lactate dehydrogenase; n=3;
Lactobacillales|Rep: Enzyme with possible activities of
L-2- hydroxyisocaproate/malate/lactate dehydrogenase -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 304
Score = 55.2 bits (127), Expect = 2e-06
Identities = 26/71 (36%), Positives = 45/71 (63%)
Frame = +3
Query: 513 RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNL 692
R ++ NT ++Q+ L + + +L++ SNPVD++T + K +GLP ++V G+GT L
Sbjct: 89 RFTELKANTPEVQQVGSDLKQAGFNGVLIVISNPVDVITGIYQKATGLPANQVFGTGTYL 148
Query: 693 DSARFRYLLSD 725
D+AR + L D
Sbjct: 149 DTARLKRALGD 159
Score = 40.7 bits (91), Expect = 0.036
Identities = 18/66 (27%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFM-RNAKIQSS 438
K+ +VG+G VG+ A ++ Q + + I LVD +KL E +D + ++ + + ++ +
Sbjct: 3 KIGVVGIGHVGVTVAHIIIAQGLADEIVLVDKNPEKLASEELDFRDAASLLDHHVEVHAG 62
Query: 439 TDYSIT 456
T +T
Sbjct: 63 TVTDLT 68
>UniRef50_A2QJT7 Cluster: Catalytic activity: precursor; n=1;
Aspergillus niger|Rep: Catalytic activity: precursor -
Aspergillus niger
Length = 307
Score = 55.2 bits (127), Expect = 2e-06
Identities = 23/56 (41%), Positives = 40/56 (71%)
Frame = +3
Query: 543 VLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFR 710
+LK I+ ++ ++P+ I+++ +NPVD LT + I+GLP+ +VIG GT +DS R +
Sbjct: 97 ILKSILNEMRPFNPNAIILVVANPVDTLTTLAQDIAGLPRKQVIGVGTCIDSLRLQ 152
Score = 39.5 bits (88), Expect = 0.083
Identities = 19/83 (22%), Positives = 45/83 (54%), Gaps = 1/83 (1%)
Frame = +1
Query: 265 VTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGS-AFMRNAKIQSST 441
+ ++G+G VG + A S++ + + + LVD+ + ++ DL + + KI+++T
Sbjct: 4 IALIGLGSVGASTALSLIHRRIQGTLLLVDIKSSLRDAQVRDLADAALVYGSVTKIEAAT 63
Query: 442 DYSITAGSKICVVTAGVRQREGD 510
+ + + + ++TAGV G+
Sbjct: 64 -HQEASQADVVIITAGVNYTPGE 85
>UniRef50_Q27743 Cluster: L-lactate dehydrogenase; n=17;
Apicomplexa|Rep: L-lactate dehydrogenase - Plasmodium
falciparum (isolate CDC / Honduras)
Length = 316
Score = 55.2 bits (127), Expect = 2e-06
Identities = 23/71 (32%), Positives = 46/71 (64%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+R DL+ N ++ +I + K P+ +++ +NPVD++ + + SG+PK+++IG G
Sbjct: 94 NRDDLLPLNNKIMIEIGGHIKKNCPNAFIIVVTNPVDVMVQLLHQHSGVPKNKIIGLGGV 153
Query: 690 LDSARFRYLLS 722
LD++R +Y +S
Sbjct: 154 LDTSRLKYYIS 164
>UniRef50_Q6JH30 Cluster: Lactate dehydrogenase; n=3; Plasmodium
(Plasmodium)|Rep: Lactate dehydrogenase - Plasmodium
vivax
Length = 299
Score = 54.8 bits (126), Expect = 2e-06
Identities = 22/71 (30%), Positives = 46/71 (64%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+R DL+ N ++ +I + P+ +++ +NPVD++ + ++ SG+PK+++IG G
Sbjct: 87 NRDDLLPLNNKIMIEIGGHIKNLCPNAFIIVVTNPVDVMVQLLFEHSGVPKNKIIGLGGV 146
Query: 690 LDSARFRYLLS 722
LD++R +Y +S
Sbjct: 147 LDTSRLKYYIS 157
>UniRef50_Q8I8U4 Cluster: Lactate dehydrogenase; n=3;
Eimeriorina|Rep: Lactate dehydrogenase - Eimeria tenella
Length = 331
Score = 54.4 bits (125), Expect = 3e-06
Identities = 26/72 (36%), Positives = 43/72 (59%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SR DL+ N +L+++ + ++ P ++ +NP+D++ + +GLP RV G
Sbjct: 99 SRKDLLPVNVKILREVGAAIKQFCPHAFVINITNPLDVMVAALREAAGLPAARVCGMAGV 158
Query: 690 LDSARFRYLLSD 725
LDSARFR LL+D
Sbjct: 159 LDSARFRRLLAD 170
>UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular
organisms|Rep: Malate dehydrogenase - Silicibacter
pomeroyi
Length = 320
Score = 54.4 bits (125), Expect = 3e-06
Identities = 26/72 (36%), Positives = 43/72 (59%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SR DL+ N V+K + + +PD ++ +NP+D + + + SGLP ++V G
Sbjct: 88 SRDDLLGINLKVMKSVGEGIRDNAPDAFVICITNPLDAMVWALQQFSGLPANKVCGMAGV 147
Query: 690 LDSARFRYLLSD 725
LDSARFR+ L++
Sbjct: 148 LDSARFRHFLAE 159
Score = 47.6 bits (108), Expect = 3e-04
Identities = 23/83 (27%), Positives = 49/83 (59%), Gaps = 1/83 (1%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDL-QHGSAFMRNAKIQSS 438
K+ ++G GQ+G A + + + ++ L D+ +G+ +D+ + G + +AK++ +
Sbjct: 5 KIALIGAGQIGGTLAHLVALKEL-GDVVLFDIAEGTPEGKALDIAESGPSEGFDAKLKGT 63
Query: 439 TDYSITAGSKICVVTAGVRQREG 507
Y+ AG+ +C+VTAGV ++ G
Sbjct: 64 QSYADIAGADVCIVTAGVPRKPG 86
>UniRef50_Q9PHY2 Cluster: Probable malate dehydrogenase; n=12;
Campylobacter|Rep: Probable malate dehydrogenase -
Campylobacter jejuni
Length = 300
Score = 54.4 bits (125), Expect = 3e-06
Identities = 26/83 (31%), Positives = 49/83 (59%), Gaps = 1/83 (1%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDL-QHGSAFMRNAKIQSS 438
K+T++G G VG + A++++ + + N I LVD+ D L + ++L Q +A N + +
Sbjct: 2 KITVIGAGNVGSSVAYALILREIANEIVLVDINEDLLYAKELELTQSIAALNLNIDLLCT 61
Query: 439 TDYSITAGSKICVVTAGVRQREG 507
DY+ T S I + +AG +++G
Sbjct: 62 KDYTHTKNSDIVLFSAGFARKDG 84
Score = 44.8 bits (101), Expect = 0.002
Identities = 21/71 (29%), Positives = 39/71 (54%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SR +L+Q NT ++ ++ ++ D + +I +NPVD L ++ ++I
Sbjct: 86 SREELLQLNTSIMLDCAKKIKDFTEDPLFIILTNPVDFLLNTLYESGIFSSKKIIAMAGV 145
Query: 690 LDSARFRYLLS 722
LD+ARF+Y L+
Sbjct: 146 LDNARFKYELA 156
>UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like
protein; n=1; Methylibium petroleiphilum PM1|Rep:
Malate/lactate dehydrogenases-like protein - Methylibium
petroleiphilum (strain PM1)
Length = 432
Score = 52.8 bits (121), Expect = 8e-06
Identities = 24/66 (36%), Positives = 42/66 (63%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SR DL N +++ + + ++P++ LVI SNP++ +T++ + +G P+ RV+G
Sbjct: 209 SRTDLTVVNAEIMTSVCRGIRTHAPNSTLVIVSNPLEEMTHLAAQQTGFPEERVLGMAGV 268
Query: 690 LDSARF 707
LDSARF
Sbjct: 269 LDSARF 274
Score = 46.8 bits (106), Expect = 5e-04
Identities = 24/83 (28%), Positives = 44/83 (53%), Gaps = 1/83 (1%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSA-FMRNAKIQSS 438
K +VG G VG A + ++ + +ALVD++ G +D+ HG+ + + ++ S
Sbjct: 125 KAGVVGAGHVGAMTALRLAESDLFSEVALVDVVPGLAAGLALDMWHGAGLYGFSTRLSGS 184
Query: 439 TDYSITAGSKICVVTAGVRQREG 507
D AG++ V+TAG ++ G
Sbjct: 185 DDLVALAGAEYIVITAGKPRQPG 207
>UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter
hepaticus|Rep: Malate dehydrogenase - Helicobacter
hepaticus
Length = 315
Score = 52.8 bits (121), Expect = 8e-06
Identities = 24/68 (35%), Positives = 41/68 (60%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+R DL+ +N ++++I + + +P ++L++ SNP+D + V + S K RVIG
Sbjct: 89 TRNDLLLKNASIIQEISSNVARIAPQSLLIVVSNPLDAMCLVAKQWSKFEKERVIGMAGI 148
Query: 690 LDSARFRY 713
LDSAR Y
Sbjct: 149 LDSARLTY 156
>UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;
Ignicoccus hospitalis KIN4/I|Rep: malate dehydrogenase
(NAD) - Ignicoccus hospitalis KIN4/I
Length = 311
Score = 51.6 bits (118), Expect = 2e-05
Identities = 26/72 (36%), Positives = 44/72 (61%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SR DL + N +++ I +L +P ++ +NPVD++T + + G K VIG+GT+
Sbjct: 91 SRRDLAKVNAQIIRDIGDKLRDRNPGAFYMVITNPVDVMTMILSDVIG-NKGTVIGTGTS 149
Query: 690 LDSARFRYLLSD 725
LD+ RFR +S+
Sbjct: 150 LDTYRFRSAVSE 161
Score = 49.2 bits (112), Expect = 1e-04
Identities = 27/85 (31%), Positives = 47/85 (55%), Gaps = 1/85 (1%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSA-FMRNAKIQSS 438
KV ++G G+VG A++M + LVD + KG M D++H +A F R+ ++++
Sbjct: 7 KVAVIGTGRVGATFAYTMAIVPGVARMVLVDAVPGLSKGVMEDIKHAAAVFRRSIQVEAY 66
Query: 439 TDYSITAGSKICVVTAGVRQREGDL 513
D S + V+TAG + R+ D+
Sbjct: 67 DDVSKVENADAIVITAG-KPRKADM 90
>UniRef50_Q6ABQ3 Cluster: L-lactate dehydrogenase; n=1;
Propionibacterium acnes|Rep: L-lactate dehydrogenase -
Propionibacterium acnes
Length = 322
Score = 51.6 bits (118), Expect = 2e-05
Identities = 23/72 (31%), Positives = 44/72 (61%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SR L Q N+ V+++++ + +Y+ +++ +NP+D+ ++ P + V+G+GT
Sbjct: 96 SRNSLAQVNSKVIREVMGNICQYTHSAPIILITNPLDVNVHIAATEFDYPTNLVVGTGTA 155
Query: 690 LDSARFRYLLSD 725
LDSAR R L+D
Sbjct: 156 LDSARLRRHLAD 167
>UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasma
hyopneumoniae|Rep: L-lactate dehydrogenase - Mycoplasma
hyopneumoniae
Length = 315
Score = 51.6 bits (118), Expect = 2e-05
Identities = 26/71 (36%), Positives = 44/71 (61%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+RL+LV N ++++I ++ + I +I +NPVDI+T SG +VIGSGT
Sbjct: 88 TRLELVADNIRIIREIALKVKESGFSGISIIVANPVDIITRAYRDASGFSDQKVIGSGTV 147
Query: 690 LDSARFRYLLS 722
LD+AR ++ ++
Sbjct: 148 LDTARLQFAIA 158
>UniRef50_Q92AZ3 Cluster: Lin1775 protein; n=13; Listeria|Rep:
Lin1775 protein - Listeria innocua
Length = 302
Score = 51.2 bits (117), Expect = 3e-05
Identities = 25/77 (32%), Positives = 45/77 (58%)
Frame = +3
Query: 495 TTRR*SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVI 674
T R R++ + + + +I+P+++ I V +NP D++T + KISG RV
Sbjct: 82 TLLREDRMEELVETSRSVTEIVPKILATGFKGIFVNITNPCDVITMLIQKISGFDHSRVF 141
Query: 675 GSGTNLDSARFRYLLSD 725
G+GT+LD+AR R ++ +
Sbjct: 142 GTGTSLDTARMRRVVGE 158
Score = 46.4 bits (105), Expect = 7e-04
Identities = 21/76 (27%), Positives = 42/76 (55%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 441
KV I+G G VG AFS++TQ + + I ++D + K + E ++L+ ++ R+ ++
Sbjct: 4 KVGIIGAGHVGSDVAFSLVTQGICDEIVIIDKIEAKAESEALELRDMASMTRSYTTITAN 63
Query: 442 DYSITAGSKICVVTAG 489
+ + + I V+ G
Sbjct: 64 SWEALSDADIIVMAVG 79
>UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4;
Epsilonproteobacteria|Rep: Malate dehydrogenase -
Wolinella succinogenes
Length = 314
Score = 51.2 bits (117), Expect = 3e-05
Identities = 25/65 (38%), Positives = 40/65 (61%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
SR DL+ N V++ ++ ++ Y +++LV+ SNP+D + Y K SGL +V+G
Sbjct: 84 SRDDLLLANAKVIRTVLSEVKPYIQESVLVMVSNPLDAMVYTAIKESGLSPLQVLGMAGI 143
Query: 690 LDSAR 704
LDSAR
Sbjct: 144 LDSAR 148
>UniRef50_Q5CYZ2 Cluster: Lactate dehydrogenase, adjacent gene
encodes predicted malate dehydrogenase; n=8;
Cryptosporidium|Rep: Lactate dehydrogenase, adjacent
gene encodes predicted malate dehydrogenase -
Cryptosporidium parvum Iowa II
Length = 337
Score = 50.8 bits (116), Expect = 3e-05
Identities = 23/70 (32%), Positives = 41/70 (58%)
Frame = +3
Query: 513 RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNL 692
R +L+ N +L + + KY P+ ++ +NP+D++ K+SGLP ++V G L
Sbjct: 106 RSELLFGNARILDSVAEGVKKYCPNAFVICITNPLDVMVSHFQKVSGLPHNKVCGMAGVL 165
Query: 693 DSARFRYLLS 722
DS+RFR ++
Sbjct: 166 DSSRFRTFIA 175
Score = 44.0 bits (99), Expect = 0.004
Identities = 22/84 (26%), Positives = 45/84 (53%), Gaps = 1/84 (1%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSA-FMRNAKIQSS 438
K+ ++G GQ+G A+ + N+ + + L D+ +G+ +D+ H F +K+ +
Sbjct: 22 KIAVIGSGQIGGNIAYIVGKDNLAD-VVLFDIAEGIPQGKALDITHSMVMFGSTSKVIGT 80
Query: 439 TDYSITAGSKICVVTAGVRQREGD 510
DY+ +GS + ++TA + R D
Sbjct: 81 NDYADISGSDVVIITASIPGRPKD 104
>UniRef50_A3CTN0 Cluster: Lactate/malate dehydrogenase; n=1;
Methanoculleus marisnigri JR1|Rep: Lactate/malate
dehydrogenase - Methanoculleus marisnigri (strain ATCC
35101 / DSM 1498 / JR1)
Length = 288
Score = 50.8 bits (116), Expect = 3e-05
Identities = 26/72 (36%), Positives = 43/72 (59%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+R DL++ N V K+ +L++ P ++ + +NP+D Y WK+ G+ + R IG G+
Sbjct: 82 TRADLLEANIPVAKRC-SELLEGFPGVVISV-TNPMDANNYGLWKMMGIDRRRCIGFGSQ 139
Query: 690 LDSARFRYLLSD 725
LDSARF L +
Sbjct: 140 LDSARFAGFLRE 151
Score = 34.7 bits (76), Expect = 2.4
Identities = 15/47 (31%), Positives = 27/47 (57%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQH 399
+ + I+GVG+VG AF + + I + D+ L+ +++DLQH
Sbjct: 2 TSLAILGVGKVGGETAFLSAALGLVDEIVVYDVYEPLLRAQVLDLQH 48
>UniRef50_P14295 Cluster: L-2-hydroxyisocaproate dehydrogenase;
n=15; Lactobacillales|Rep: L-2-hydroxyisocaproate
dehydrogenase - Lactobacillus confusus
Length = 310
Score = 50.0 bits (114), Expect = 6e-05
Identities = 20/40 (50%), Positives = 31/40 (77%)
Frame = +3
Query: 591 ILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFR 710
+LV+ SNPVD++T + ++G P H+VIG+GT LD+AR +
Sbjct: 118 VLVVISNPVDVITALFQHVTGFPAHKVIGTGTLLDTARMQ 157
>UniRef50_Q88ZG9 Cluster: L-2-hydroxyisocaproate dehydrogenase; n=2;
Lactobacillus plantarum|Rep: L-2-hydroxyisocaproate
dehydrogenase - Lactobacillus plantarum
Length = 319
Score = 49.6 bits (113), Expect = 8e-05
Identities = 24/76 (31%), Positives = 40/76 (52%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 441
K I+GVG VG A++++ + + + + L+D A K + E +DLQ A + + I
Sbjct: 3 KYAIIGVGHVGATIAYTLVCKGIADELVLIDTNAAKARAEQLDLQDAQARLDSRTIIKIN 62
Query: 442 DYSITAGSKICVVTAG 489
DY + I VT+G
Sbjct: 63 DYHELDDTDILFVTSG 78
Score = 39.1 bits (87), Expect = 0.11
Identities = 16/61 (26%), Positives = 38/61 (62%)
Frame = +3
Query: 543 VLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLS 722
+++ I P++ + +++ NP D +T+ + +GL + +V G+GT LD+AR + +++
Sbjct: 100 IVQDIAPKVKATKFNGVVIDTMNPCDAITHYFQRATGLSRQQVFGTGTFLDTARMQKVVA 159
Query: 723 D 725
+
Sbjct: 160 E 160
>UniRef50_Q04GC4 Cluster: Enzyme with possible activities of L-2-
hydroxyisocaproate/malate/lactate dehydrogenase; n=2;
Oenococcus oeni|Rep: Enzyme with possible activities of
L-2- hydroxyisocaproate/malate/lactate dehydrogenase -
Oenococcus oeni (strain BAA-331 / PSU-1)
Length = 304
Score = 49.2 bits (112), Expect = 1e-04
Identities = 24/62 (38%), Positives = 39/62 (62%)
Frame = +3
Query: 525 VQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSAR 704
+Q N ++ + QL K D + + +NPVD++T V + LPK++VIG+GT LDS+R
Sbjct: 93 LQFNVKQIRSMAEQLKKVHFDGVFLTITNPVDVITAVYQRELALPKNQVIGTGTFLDSSR 152
Query: 705 FR 710
+
Sbjct: 153 LK 154
>UniRef50_Q5M0L6 Cluster: L-2-hydroxyisocaproate dehydrogenase; n=3;
Streptococcus thermophilus|Rep: L-2-hydroxyisocaproate
dehydrogenase - Streptococcus thermophilus (strain CNRZ
1066)
Length = 316
Score = 48.0 bits (109), Expect = 2e-04
Identities = 23/57 (40%), Positives = 37/57 (64%)
Frame = +3
Query: 540 DVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFR 710
+ + Q+ +L + IL++ SNPVD +T + + +G PK RVIG+GT LD+AR +
Sbjct: 100 EAVYQVAQELKQLDFKGILLVISNPVDAVTALYQEFTGWPKERVIGTGTLLDTARMK 156
>UniRef50_O52354 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
gallisepticum|Rep: L-lactate dehydrogenase - Mycoplasma
gallisepticum
Length = 323
Score = 47.6 bits (108), Expect = 3e-04
Identities = 21/71 (29%), Positives = 41/71 (57%)
Frame = +3
Query: 513 RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNL 692
RL L+ N +L +I +L + + +I +NP D++ V K++G H++I +G L
Sbjct: 94 RLQLMTANVKILNEIALELKRVGFKGLSIIPTNPCDVMAGVYQKVTGFDPHKIISTGCQL 153
Query: 693 DSARFRYLLSD 725
++ R R ++S+
Sbjct: 154 ETMRTRKMISE 164
>UniRef50_A4E9T4 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 325
Score = 46.8 bits (106), Expect = 5e-04
Identities = 22/62 (35%), Positives = 33/62 (53%)
Frame = +3
Query: 537 TDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYL 716
TD + +++ D I V SNP D++ W ++G ++IGSG LDSAR R
Sbjct: 100 TDAARSFAKRIVDAGFDGIFVSISNPCDVVCTELWHLTGYDPKKIIGSGCGLDSARLRTE 159
Query: 717 LS 722
+S
Sbjct: 160 IS 161
>UniRef50_Q6A6E3 Cluster: L-lactate dehydrogenase; n=1;
Propionibacterium acnes|Rep: L-lactate dehydrogenase -
Propionibacterium acnes
Length = 321
Score = 46.4 bits (105), Expect = 7e-04
Identities = 22/72 (30%), Positives = 41/72 (56%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+R +L N +++ + Q+ + D ++I SNP+D L ++ P+ V+G+GT
Sbjct: 97 ARRELAATNGKIIRSTMTQITSRNHDAAIIICSNPLDALVHIASTEFDHPQGLVLGTGTI 156
Query: 690 LDSARFRYLLSD 725
LDSAR +++D
Sbjct: 157 LDSARMCRVVAD 168
>UniRef50_Q8IE66 Cluster: Oxidoreductase, putative; n=6;
Plasmodium|Rep: Oxidoreductase, putative - Plasmodium
falciparum (isolate 3D7)
Length = 334
Score = 46.4 bits (105), Expect = 7e-04
Identities = 20/64 (31%), Positives = 37/64 (57%)
Frame = +3
Query: 534 NTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRY 713
N +LK++ L K+ P +V+ ++PVD + V + + +P H++ G L SAR R+
Sbjct: 105 NVKLLKEVAKSLKKHCPQAFVVVTTSPVDCMAKVLQEHANIPPHKICGMAGVLHSARLRH 164
Query: 714 LLSD 725
L++
Sbjct: 165 NLAE 168
>UniRef50_Q38YI2 Cluster: Putative malate dehydrogenase; n=1;
Lactobacillus sakei subsp. sakei 23K|Rep: Putative
malate dehydrogenase - Lactobacillus sakei subsp. sakei
(strain 23K)
Length = 301
Score = 46.0 bits (104), Expect = 0.001
Identities = 23/66 (34%), Positives = 37/66 (56%)
Frame = +3
Query: 513 RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNL 692
R D + + Q P+L + IL+ +NP D++T ++G PK RV+G+GT L
Sbjct: 89 RFDELTYTKTAVAQWAPKLKAANFKGILLNITNPCDVITQYLQALTGFPKERVLGTGTTL 148
Query: 693 DSARFR 710
D+AR +
Sbjct: 149 DTARMQ 154
Score = 38.3 bits (85), Expect = 0.19
Identities = 19/77 (24%), Positives = 38/77 (49%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 438
+KV I+G+G VG A++++++ + + + L D + E DL+ G ++
Sbjct: 2 NKVAIIGIGHVGSTVAYTLVSRRICSELVLFDQKPKLAEAERNDLEAGQVDHTGFVKITA 61
Query: 439 TDYSITAGSKICVVTAG 489
D S A + + +AG
Sbjct: 62 NDESQLATCDLVIFSAG 78
>UniRef50_Q82R06 Cluster: Putative lactate dehydrogenase; n=1;
Streptomyces avermitilis|Rep: Putative lactate
dehydrogenase - Streptomyces avermitilis
Length = 303
Score = 45.2 bits (102), Expect = 0.002
Identities = 27/63 (42%), Positives = 40/63 (63%)
Frame = +3
Query: 534 NTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRY 713
N V++ + L Y T+LV+ +NPVD++T + + SG P RV G G+NLDSAR+R
Sbjct: 97 NAPVIRALATTLRGYQ-GTVLVV-TNPVDLMTRLFAETSGCP--RVYGIGSNLDSARYRL 152
Query: 714 LLS 722
L+
Sbjct: 153 TLA 155
>UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|Rep:
Malate dehydrogenase - Plasmodium falciparum
Length = 313
Score = 45.2 bits (102), Expect = 0.002
Identities = 21/72 (29%), Positives = 39/72 (54%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+R DL+ N ++K + + + ++ SNP+DI+ V K S LP ++ G
Sbjct: 86 TREDLIGVNGKIMKSVAESVKLHCSKAFVICVSNPLDIMVNVFHKFSNLPHEKICGMAGI 145
Query: 690 LDSARFRYLLSD 725
LD++R+ L++D
Sbjct: 146 LDTSRYCSLIAD 157
Score = 44.0 bits (99), Expect = 0.004
Identities = 24/84 (28%), Positives = 46/84 (54%), Gaps = 1/84 (1%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMR-NAKIQS 435
+K+ ++G GQ+G L +N+ ++ L D++ +G+ +DL+H S + N I
Sbjct: 2 TKIALIGSGQIGAIVGELCLLENL-GDLILYDVVPGIPQGKALDLKHFSTILGVNRNILG 60
Query: 436 STDYSITAGSKICVVTAGVRQREG 507
+ + I V+TAGV+++EG
Sbjct: 61 TNQIEDIKDADIIVITAGVQRKEG 84
>UniRef50_A5IYS9 Cluster: L-lactate dehydrogenase; n=2;
Mycoplasma|Rep: L-lactate dehydrogenase - Mycoplasma
agalactiae
Length = 323
Score = 42.3 bits (95), Expect = 0.012
Identities = 21/70 (30%), Positives = 38/70 (54%)
Frame = +3
Query: 513 RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNL 692
R+ L N +++ L I+V+A+NP D++ S +P +RVI +GTNL
Sbjct: 90 RMALAGANAKLMQSFAKDLDAAGFKGIVVVAANPCDVMAAAVHYGSKIPANRVISAGTNL 149
Query: 693 DSARFRYLLS 722
++ R + +L+
Sbjct: 150 ETGRLKKMLA 159
>UniRef50_Q034P5 Cluster: Enzyme with possible activities of L-2-
hydroxyisocaproate/malate/lactate dehydrogenase; n=1;
Lactobacillus casei ATCC 334|Rep: Enzyme with possible
activities of L-2- hydroxyisocaproate/malate/lactate
dehydrogenase - Lactobacillus casei (strain ATCC 334)
Length = 301
Score = 41.5 bits (93), Expect = 0.021
Identities = 15/44 (34%), Positives = 30/44 (68%)
Frame = +1
Query: 265 VTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQ 396
+ I+G+G VG+ AF+++++ V + + L+D A+ +GE DL+
Sbjct: 5 IGIIGIGHVGVTTAFNLVSKGVADKLVLIDKKAELAEGESFDLK 48
Score = 39.5 bits (88), Expect = 0.083
Identities = 20/60 (33%), Positives = 34/60 (56%)
Frame = +3
Query: 546 LKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSD 725
L + P+L +L+ +NP D +T + LPK ++IG+GT+LD+ R R ++D
Sbjct: 100 LDDVAPKLKASGFHGVLLDITNPCDAVTSYWQYLLDLPKSQIIGTGTSLDTYRMRRAVAD 159
>UniRef50_A2SR33 Cluster: Lactate/malate dehydrogenase; n=1;
Methanocorpusculum labreanum Z|Rep: Lactate/malate
dehydrogenase - Methanocorpusculum labreanum (strain
ATCC 43576 / DSM 4855 / Z)
Length = 283
Score = 41.5 bits (93), Expect = 0.021
Identities = 24/70 (34%), Positives = 39/70 (55%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+R DL +N + K+ L +S L++ +NP+D+ T+ K S L + +V+G G
Sbjct: 81 TRADLFDKNLPIAKESSELLKGFSGK--LIVVTNPMDVFTWYFAKKSCLDESQVVGFGGL 138
Query: 690 LDSARFRYLL 719
LDS RF +L
Sbjct: 139 LDSRRFTVVL 148
>UniRef50_Q5FIY9 Cluster: L-LDH; n=6; Lactobacillus|Rep: L-LDH -
Lactobacillus acidophilus
Length = 304
Score = 40.3 bits (90), Expect = 0.047
Identities = 16/45 (35%), Positives = 27/45 (60%)
Frame = +1
Query: 262 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQ 396
KV I+G+G VG A+++ T + + + L+D DK+ E DL+
Sbjct: 3 KVGIIGMGHVGATVAYTLFTHGIADELVLIDKNEDKVAAEYNDLR 47
Score = 39.5 bits (88), Expect = 0.083
Identities = 16/45 (35%), Positives = 31/45 (68%)
Frame = +3
Query: 591 ILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSD 725
+L+ SNP D + + + +GL K++V+G+GT LD+AR + ++ +
Sbjct: 115 VLLNISNPCDAVAQILQETTGLSKNQVLGTGTFLDTARMQRIIGE 159
>UniRef50_Q1FMY2 Cluster: L-lactate dehydrogenase; n=1; Clostridium
phytofermentans ISDg|Rep: L-lactate dehydrogenase -
Clostridium phytofermentans ISDg
Length = 319
Score = 39.1 bits (87), Expect = 0.11
Identities = 18/72 (25%), Positives = 38/72 (52%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
+R+ + ++K++ + D ++V SNP D++T+ + +++I + T
Sbjct: 91 TRMSTLTNTALIIKEVAWHIKNSGFDGMIVSISNPADVITHYLQHLLQYSSNKIISTSTV 150
Query: 690 LDSARFRYLLSD 725
LDSAR R ++D
Sbjct: 151 LDSARLRRAIAD 162
>UniRef50_Q091H7 Cluster: Oxidoreductase; n=2; Myxococcales|Rep:
Oxidoreductase - Stigmatella aurantiaca DW4/3-1
Length = 481
Score = 37.1 bits (82), Expect = 0.44
Identities = 23/66 (34%), Positives = 39/66 (59%), Gaps = 1/66 (1%)
Frame = +1
Query: 184 LRELPQDGVPEEA-VPARAREGGRNWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMM 360
L++L + P+ + V +R + G++ V I+G GQ G++ AF +L + VT N+ +VD
Sbjct: 24 LKDLERLAYPKRSWVLSRRSQEGQSILDVLIIGGGQSGLSVAFGLLREKVT-NVLVVDDN 82
Query: 361 ADKLKG 378
A L G
Sbjct: 83 APGLAG 88
>UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;
n=2; Apis mellifera|Rep: PREDICTED: similar to CG7998-PA
- Apis mellifera
Length = 333
Score = 36.7 bits (81), Expect = 0.58
Identities = 18/72 (25%), Positives = 39/72 (54%), Gaps = 3/72 (4%)
Frame = +3
Query: 519 DLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVT---WKISGLPKHRVIGSGTN 689
++++ N +L ++P +IK+SP +L I NP++ L +T +K +G+ ++ I N
Sbjct: 87 EVLKSNAIILSDLLPNIIKFSPQAMLAIVMNPINSLIPLTMEMYKKAGIYEYNRIFGVMN 146
Query: 690 LDSARFRYLLSD 725
+ + +D
Sbjct: 147 FECLKANSFTAD 158
>UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa
triquetra|Rep: Malate dehydrogenase - Heterocapsa
triquetra (Dinoflagellate)
Length = 402
Score = 36.3 bits (80), Expect = 0.77
Identities = 23/68 (33%), Positives = 35/68 (51%), Gaps = 3/68 (4%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYV---TWKISGLPKHRVIGS 680
+R DL + N D+ K I+ KY PD +L + NPV+ + +K GL +++G
Sbjct: 175 TRDDLFKINADIAKGIVEACAKYCPDAMLGMIVNPVNSVVPAMAELYKKKGLDPMKIVGI 234
Query: 681 GTNLDSAR 704
T LD R
Sbjct: 235 -TTLDVVR 241
>UniRef50_Q4RTQ4 Cluster: Chromosome 2 SCAF14997, whole genome
shotgun sequence; n=4; Clupeocephala|Rep: Chromosome 2
SCAF14997, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 504
Score = 34.7 bits (76), Expect = 2.4
Identities = 18/55 (32%), Positives = 29/55 (52%)
Frame = +1
Query: 253 NWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMR 417
N+ ++ IV V V +++L N T IA +D A + K +M L+H FM+
Sbjct: 291 NYVEMWIVMVSMVSGCIMYTVLVANATTMIANIDPAAKEYKSKMSRLEHYMTFMK 345
>UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4;
Bacteroidales|Rep: Malate dehydrogenase - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 334
Score = 34.3 bits (75), Expect = 3.1
Identities = 23/68 (33%), Positives = 35/68 (51%), Gaps = 1/68 (1%)
Frame = +3
Query: 510 SRLDLVQRNTDVLKQIIPQLIKYSPDTI-LVIASNPVDILTYVTWKISGLPKHRVIGSGT 686
+R DL++ N ++ Q+ + Y PD ++I NP DI VT SGL K + +
Sbjct: 91 TREDLLKGNAEIAAQLGKDIKSYCPDCKHVIIIFNPADITGLVTLIYSGL-KPSQVTTLA 149
Query: 687 NLDSARFR 710
LDS R +
Sbjct: 150 GLDSTRLQ 157
>UniRef50_Q02D27 Cluster: Oxidoreductase domain protein; n=1;
Solibacter usitatus Ellin6076|Rep: Oxidoreductase domain
protein - Solibacter usitatus (strain Ellin6076)
Length = 444
Score = 34.3 bits (75), Expect = 3.1
Identities = 22/74 (29%), Positives = 33/74 (44%), Gaps = 1/74 (1%)
Frame = +1
Query: 226 PARAREGGRNWSKVTIVGVGQVGMAAAFSMLTQNV-TNNIALVDMMADKLKGEMMDLQHG 402
P R G+ + +VG G G A MLT N +A+ D+ D L+G + +L+
Sbjct: 28 PHLVRGAGKETLRAGLVGCGGRGTQATVDMLTGNENVELVAMADIFEDHLEGALKNLRDP 87
Query: 403 SAFMRNAKIQSSTD 444
R+A I D
Sbjct: 88 KYVARHAGITVERD 101
>UniRef50_A0QSN0 Cluster: Ftsk/spoiiie family protein; n=1;
Mycobacterium smegmatis str. MC2 155|Rep: Ftsk/spoiiie
family protein - Mycobacterium smegmatis (strain ATCC
700084 / mc(2)155)
Length = 1211
Score = 34.3 bits (75), Expect = 3.1
Identities = 23/64 (35%), Positives = 35/64 (54%), Gaps = 2/64 (3%)
Frame = +1
Query: 277 GVGQVGMAAA--FSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSSTDYS 450
G +G+A+A S L N+++ A+V MAD L GEM Q +R A + S+ +Y+
Sbjct: 443 GATFLGLASAPHISALITNLSDEAAMVARMADALAGEMTRRQE---LLRAANVGSAAEYT 499
Query: 451 ITAG 462
T G
Sbjct: 500 RTNG 503
>UniRef50_A2YRW8 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. indica (Rice)
Length = 127
Score = 34.3 bits (75), Expect = 3.1
Identities = 18/46 (39%), Positives = 31/46 (67%), Gaps = 4/46 (8%)
Frame = +3
Query: 510 SRLDLVQRN--TDVLKQIIPQLIKYSPDTILVIASNPV--DILTYV 635
++L+L++ N +L +I+P L + SP+ LV+ S+P D+LTYV
Sbjct: 3 TKLELMRSNYLKKLLTEIVPALAENSPEAALVVVSDPPVDDVLTYV 48
>UniRef50_Q0UTY3 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 313
Score = 34.3 bits (75), Expect = 3.1
Identities = 26/73 (35%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
Frame = +1
Query: 193 LPQDGVPEEAV-PARAREGGRNWSKVTIV-GVGQVGMAAAFSMLTQNVTNNIALVDMMAD 366
LP P E + PA ++ N KV ++ G GQ G+ AA + N+A++D+ D
Sbjct: 11 LPMQHAPYETISPATLKDS--NEGKVALITGAGQ-GIGAAIAEALAKSGANVAILDLNTD 67
Query: 367 KL-KGEMMDLQHG 402
KL K + LQHG
Sbjct: 68 KLVKTKEACLQHG 80
>UniRef50_Q6NYY8 Cluster: Smox protein; n=12; Coelomata|Rep: Smox
protein - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 539
Score = 33.9 bits (74), Expect = 4.1
Identities = 15/52 (28%), Positives = 27/52 (51%)
Frame = +1
Query: 247 GRNWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHG 402
G ++ ++G G G+AA ++L TN L +D++ G + +QHG
Sbjct: 21 GHRQPRIVVIGAGLAGLAATKTLLENGFTNVTVL--EASDRIGGRVQSIQHG 70
>UniRef50_Q8EYH1 Cluster: Methyl-accepting chemotaxis protein; n=2;
Leptospira interrogans|Rep: Methyl-accepting chemotaxis
protein - Leptospira interrogans
Length = 530
Score = 33.9 bits (74), Expect = 4.1
Identities = 20/55 (36%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
Frame = -3
Query: 682 PDPMTRCLGSPLIFHVTYVRI-STGLLAITNIVSGLYFISCGIICLRTSVFLCTR 521
PD T + SP+++ ++Y+ I S+GLL + N V + F+S G L ++F TR
Sbjct: 105 PDFTTGVVKSPILYGISYMYIVSSGLLLVPNFVLWIGFLSGGAQAL--AIFTATR 157
>UniRef50_Q1U8H4 Cluster: L-lactate dehydrogenase; n=2;
Lactobacillus reuteri|Rep: L-lactate dehydrogenase -
Lactobacillus reuteri 100-23
Length = 307
Score = 33.5 bits (73), Expect = 5.4
Identities = 18/51 (35%), Positives = 31/51 (60%)
Frame = +3
Query: 552 QIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSAR 704
Q+ ++ K IL+ +NP + +T V + GLP+ +VIG GT +++AR
Sbjct: 100 QVGNKVFKSDFSGILINLTNPNEAITAVLQQKVGLPQKQVIGIGTVVETAR 150
>UniRef50_Q15ST6 Cluster: UBA/THIF-type NAD/FAD binding fold; n=2;
Alteromonadales|Rep: UBA/THIF-type NAD/FAD binding fold
- Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 256
Score = 33.5 bits (73), Expect = 5.4
Identities = 23/74 (31%), Positives = 38/74 (51%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 438
SKV I+GVG +G AAA +++ + I LVD +L + H + K+ S+
Sbjct: 37 SKVLIIGVGGLGCAAAQYLVSSGI-GEITLVDDDKVELSNLHRQVLHHEQDVGVKKVDSA 95
Query: 439 TDYSITAGSKICVV 480
S+ A + +CV+
Sbjct: 96 KT-SLLANNSLCVI 108
>UniRef50_A0UYP0 Cluster: Amine oxidase; n=1; Clostridium
cellulolyticum H10|Rep: Amine oxidase - Clostridium
cellulolyticum H10
Length = 572
Score = 33.5 bits (73), Expect = 5.4
Identities = 19/58 (32%), Positives = 31/58 (53%)
Frame = +1
Query: 211 PEEAVPARAREGGRNWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEM 384
P E + A AR G V I+G G GMAAAF + + + +I +++ D++ G +
Sbjct: 51 PSENITAIARPGQFKGKSVGIIGGGLAGMAAAFEL--RKLGFDITILEASEDRIGGRV 106
>UniRef50_Q8IMQ3 Cluster: CG31077-PA; n=1; Drosophila
melanogaster|Rep: CG31077-PA - Drosophila melanogaster
(Fruit fly)
Length = 1003
Score = 33.5 bits (73), Expect = 5.4
Identities = 15/35 (42%), Positives = 20/35 (57%)
Frame = -3
Query: 586 SGLYFISCGIICLRTSVFLCTRSRRDHLRVVEHQQ 482
SG YF CL +C +SR++H R+VEH Q
Sbjct: 361 SGRYFNVTQGECLADLYEVCLKSRKEHFRIVEHHQ 395
>UniRef50_UPI00015C41A2 Cluster: hypothetical protein SGO_0439; n=1;
Streptococcus gordonii str. Challis substr. CH1|Rep:
hypothetical protein SGO_0439 - Streptococcus gordonii
str. Challis substr. CH1
Length = 97
Score = 33.1 bits (72), Expect = 7.2
Identities = 25/90 (27%), Positives = 47/90 (52%), Gaps = 2/90 (2%)
Frame = +1
Query: 259 SKVTIV-GVGQVGMAAAFSM-LTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQ 432
S++TI G VG+A ++ L + + ++ + +G+ ++LQ G +FM++ KIQ
Sbjct: 2 SEITITRDTGMVGVAQKVAVYLNGELVDKLSNNETRTLAFEGDSVELQVGQSFMKSHKIQ 61
Query: 433 SSTDYSITAGSKICVVTAGVRQREGDLVSI 522
+ G K+ V +G+R G L +I
Sbjct: 62 ------VKNGQKVLVKASGIRVMLGILGTI 85
>UniRef50_Q1MTF8 Cluster: Novel protein; n=4; Danio rerio|Rep: Novel
protein - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 1308
Score = 33.1 bits (72), Expect = 7.2
Identities = 17/54 (31%), Positives = 27/54 (50%)
Frame = +1
Query: 403 SAFMRNAKIQSSTDYSITAGSKICVVTAGVRQREGDLVSISCRETPMFLNK*SR 564
S F++ + S +YS+ V G + GD+VS+SC E +F+ K R
Sbjct: 291 SCFLKEGWVLSWNEYSVYVVDCTNQVIIGGLESSGDIVSVSCTENEIFILKGDR 344
>UniRef50_Q1D1Z7 Cluster: Putative uncharacterized protein; n=1;
Myxococcus xanthus DK 1622|Rep: Putative uncharacterized
protein - Myxococcus xanthus (strain DK 1622)
Length = 473
Score = 33.1 bits (72), Expect = 7.2
Identities = 27/87 (31%), Positives = 43/87 (49%)
Frame = +1
Query: 217 EAVPARAREGGRNWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQ 396
E PA ARE +WS ++G +G AA L Q + N+A + ++ +L+GE +
Sbjct: 68 ERAPALAREFLEHWSTTVLLG-RLLGPAAVGPGLIQCLMGNLASL-LIVQRLRGE---VT 122
Query: 397 HGSAFMRNAKIQSSTDYSITAGSKICV 477
HG AF + T Y + G ++ V
Sbjct: 123 HGEAFF----VTPRTLYCLPRGERLDV 145
>UniRef50_A1T9V4 Cluster: FAD dependent oxidoreductase; n=1;
Mycobacterium vanbaalenii PYR-1|Rep: FAD dependent
oxidoreductase - Mycobacterium vanbaalenii (strain DSM
7251 / PYR-1)
Length = 473
Score = 33.1 bits (72), Expect = 7.2
Identities = 19/62 (30%), Positives = 27/62 (43%)
Frame = +1
Query: 163 DKQHQRALRELPQDGVPEEAVPARAREGGRNWSKVTIVGVGQVGMAAAFSMLTQNVTNNI 342
D +R REL P + G V IVG GQ G+ AF++ + +TN +
Sbjct: 5 DALAERVRRELELTAYPRPQWLTSRQHDGEPVVDVLIVGGGQAGLTVAFALKRRAITNTV 64
Query: 343 AL 348
L
Sbjct: 65 IL 66
>UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=1;
Entamoeba histolytica|Rep: NAD-specific malate
dehydrogenase 2 - Entamoeba histolytica
Length = 329
Score = 33.1 bits (72), Expect = 7.2
Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
Frame = +3
Query: 513 RLDLVQRNTDVLKQIIPQLIKYS-PDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTN 689
R DL+ N V++ L YS D +V+ +NP + YV K SG+P + T
Sbjct: 105 RSDLINVNKKVMEMNGKALGTYSNKDVRVVVVANPANTNAYVICKTSGIPPEHITAL-TR 163
Query: 690 LDSAR 704
LD R
Sbjct: 164 LDQNR 168
>UniRef50_Q6ANF8 Cluster: Related to dipeptidase; n=17;
Bacteria|Rep: Related to dipeptidase - Desulfotalea
psychrophila
Length = 404
Score = 32.7 bits (71), Expect = 9.5
Identities = 15/37 (40%), Positives = 19/37 (51%), Gaps = 1/37 (2%)
Frame = +1
Query: 586 TQYW*SPVTPWIF*RMLRGR-LAGCPSTASSGPALTW 693
TQ+W SP PW G+ +A P +SG A TW
Sbjct: 64 TQFWESPTRPWFLIIPTEGKPIAVIPGIGASGMAATW 100
>UniRef50_Q5H1J1 Cluster: Glyoxylase I family protein; n=2;
Xanthomonas oryzae pv. oryzae|Rep: Glyoxylase I family
protein - Xanthomonas oryzae pv. oryzae
Length = 213
Score = 32.7 bits (71), Expect = 9.5
Identities = 11/40 (27%), Positives = 21/40 (52%)
Frame = -2
Query: 254 FRPPSRARAGTASSGTPSCGSSRNARWCCLSPSQILFNTC 135
+RP + T ++ +PS + RW C +++ +NTC
Sbjct: 130 WRPKTFVSTNTPAAASPSSPTRMTCRWSCTRSAELAYNTC 169
>UniRef50_Q577J1 Cluster: Alcohol dehydrogenase, zinc-containing;
n=36; Bacteria|Rep: Alcohol dehydrogenase,
zinc-containing - Brucella abortus
Length = 375
Score = 32.7 bits (71), Expect = 9.5
Identities = 18/38 (47%), Positives = 22/38 (57%)
Frame = +1
Query: 259 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKL 372
S+V I G+G VG+AA + T IAL DM DKL
Sbjct: 195 SRVAIAGLGGVGLAAVMGAVAAGATEIIAL-DMFDDKL 231
>UniRef50_A1TDB4 Cluster: Amine oxidase precursor; n=2;
Mycobacterium|Rep: Amine oxidase precursor -
Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1)
Length = 445
Score = 32.7 bits (71), Expect = 9.5
Identities = 19/51 (37%), Positives = 25/51 (49%)
Frame = +1
Query: 121 DTTVGQVLNNI*DGDKQHQRALRELPQDGVPEEAVPARAREGGRNWSKVTI 273
DTT G V+ + A R L GVP V AR+R GGR W+ ++
Sbjct: 30 DTTRGHVV--VVGAGMSGLAAARRLTDAGVPVTVVEARSRIGGRTWTDTSL 78
>UniRef50_Q6ZCA3 Cluster: Putative uncharacterized protein
P0547A06.25; n=1; Oryza sativa (japonica
cultivar-group)|Rep: Putative uncharacterized protein
P0547A06.25 - Oryza sativa subsp. japonica (Rice)
Length = 187
Score = 32.7 bits (71), Expect = 9.5
Identities = 17/45 (37%), Positives = 30/45 (66%), Gaps = 4/45 (8%)
Frame = +3
Query: 510 SRLDLVQRN--TDVLKQIIPQLIKYSPDTILVIASNPV--DILTY 632
++L+L++ N +L +I+P L + SP+ LV+ S+P D+LTY
Sbjct: 3 TKLELMRSNYLKKLLTEIVPALAENSPEAALVVVSDPPVDDVLTY 47
>UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 365
Score = 32.7 bits (71), Expect = 9.5
Identities = 21/84 (25%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +1
Query: 262 KVTIVGV-GQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 438
KV ++G G +G + + +++AL D+ +D G DL H + +
Sbjct: 3 KVCVLGASGGIGQPLSLLLKLNPYVSDLALYDI-SDITAGVAKDLSHINTNSDSEGYNKD 61
Query: 439 TDY-SITAGSKICVVTAGVRQREG 507
D+ ++ GS++ +VTAG+ ++ G
Sbjct: 62 EDFKNLLEGSELVIVTAGIPRKPG 85
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 709,244,342
Number of Sequences: 1657284
Number of extensions: 14321283
Number of successful extensions: 52596
Number of sequences better than 10.0: 158
Number of HSP's better than 10.0 without gapping: 46955
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 52361
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 59090914597
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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