Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= e40h0775
(780 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L39793-1|AAA82869.1| 876|Homo sapiens nuclear factor p97 protein. 124 3e-28
L38951-1|AAC41763.1| 876|Homo sapiens importin beta subunit pro... 124 3e-28
BT009797-1|AAP88799.1| 876|Homo sapiens karyopherin (importin) ... 124 3e-28
BC036703-1|AAH36703.1| 876|Homo sapiens karyopherin (importin) ... 124 3e-28
BC024045-1|AAH24045.1| 876|Homo sapiens karyopherin (importin) ... 124 3e-28
BC003572-1|AAH03572.1| 876|Homo sapiens karyopherin (importin) ... 124 3e-28
X78712-1|CAA55365.1| 553|Homo sapiens glycerol kinase protein. 32 2.0
BC128152-1|AAI28153.1| 446|Homo sapiens AGBL1 protein protein. 32 2.0
BC058888-1|AAH58888.1| 553|Homo sapiens glycerol kinase 2 protein. 32 2.0
BC048274-1|AAH48274.2| 553|Homo sapiens glycerol kinase 2 protein. 32 2.0
BC029820-1|AAH29820.1| 553|Homo sapiens glycerol kinase 2 protein. 32 2.0
AK056872-1|BAB71299.1| 478|Homo sapiens protein ( Homo sapiens ... 32 2.0
CR457367-1|CAG33648.1| 757|Homo sapiens IPO4 protein. 31 6.1
BC110804-1|AAI10805.1| 1081|Homo sapiens importin 4 protein. 31 6.1
BC003690-1|AAH03690.2| 787|Homo sapiens IPO4 protein protein. 31 6.1
AB208897-1|BAD92134.1| 758|Homo sapiens IPO4 protein variant pr... 31 6.1
>L39793-1|AAA82869.1| 876|Homo sapiens nuclear factor p97 protein.
Length = 876
Score = 124 bits (300), Expect = 3e-28
Identities = 55/84 (65%), Positives = 71/84 (84%)
Frame = +1
Query: 256 GLTGDICRALKNKMAPYCDEIIVLLLENLGDPSIHRSVKPEILSVFGDIALSIGSDFGKY 435
GL GD+CRAL++ + P+CDE++ LLLENLG+ ++HRSVKP+ILSVFGDIAL+IG +F KY
Sbjct: 672 GLVGDLCRALQSNIIPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDIALAIGGEFKKY 731
Query: 436 FDVVMQMLLQASNAQVDHNDYDMV 507
+VV+ L QAS AQVD +DYDMV
Sbjct: 732 LEVVLNTLQQASQAQVDKSDYDMV 755
Score = 107 bits (258), Expect = 3e-23
Identities = 55/81 (67%), Positives = 64/81 (79%)
Frame = +2
Query: 11 VLKKVTPDDAPQISDTIMTALLTVFASNAGKAGSVQEDALMAVSTLVEVLGEEFLKYMDT 190
VL+KV DA QISD +M +LL +F S AG +G VQEDALMAVSTLVEVLG EFLKYM+
Sbjct: 591 VLRKVQHQDALQISDVVMASLLRMFQSTAG-SGGVQEDALMAVSTLVEVLGGEFLKYMEA 649
Query: 191 FKKYLYTGLKNHQEYQVCIAA 253
FK +L GLKN+ EYQVC+AA
Sbjct: 650 FKPFLGIGLKNYAEYQVCLAA 670
Score = 82.2 bits (194), Expect = 2e-15
Identities = 37/77 (48%), Positives = 53/77 (68%)
Frame = +3
Query: 531 SVLEAYTGIIQGLKGVGSQVRPDIAIVEPHVPAIVNFMIQVANEEDRTDAQMAVISGLMG 710
S LEAYTGI+QGLKG V PD+ +V+P V I++F+ +A +ED TD +A +GL+G
Sbjct: 764 SCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAGLIG 823
Query: 711 DLTNAFGAHVLPMLDTK 761
DL AFG VL +++ +
Sbjct: 824 DLCTAFGKDVLKLVEAR 840
>L38951-1|AAC41763.1| 876|Homo sapiens importin beta subunit
protein.
Length = 876
Score = 124 bits (300), Expect = 3e-28
Identities = 55/84 (65%), Positives = 71/84 (84%)
Frame = +1
Query: 256 GLTGDICRALKNKMAPYCDEIIVLLLENLGDPSIHRSVKPEILSVFGDIALSIGSDFGKY 435
GL GD+CRAL++ + P+CDE++ LLLENLG+ ++HRSVKP+ILSVFGDIAL+IG +F KY
Sbjct: 672 GLVGDLCRALQSNIIPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDIALAIGGEFKKY 731
Query: 436 FDVVMQMLLQASNAQVDHNDYDMV 507
+VV+ L QAS AQVD +DYDMV
Sbjct: 732 LEVVLNTLQQASQAQVDKSDYDMV 755
Score = 107 bits (258), Expect = 3e-23
Identities = 55/81 (67%), Positives = 64/81 (79%)
Frame = +2
Query: 11 VLKKVTPDDAPQISDTIMTALLTVFASNAGKAGSVQEDALMAVSTLVEVLGEEFLKYMDT 190
VL+KV DA QISD +M +LL +F S AG +G VQEDALMAVSTLVEVLG EFLKYM+
Sbjct: 591 VLRKVQHQDALQISDVVMASLLRMFQSTAG-SGGVQEDALMAVSTLVEVLGGEFLKYMEA 649
Query: 191 FKKYLYTGLKNHQEYQVCIAA 253
FK +L GLKN+ EYQVC+AA
Sbjct: 650 FKPFLGIGLKNYAEYQVCLAA 670
Score = 82.2 bits (194), Expect = 2e-15
Identities = 37/77 (48%), Positives = 53/77 (68%)
Frame = +3
Query: 531 SVLEAYTGIIQGLKGVGSQVRPDIAIVEPHVPAIVNFMIQVANEEDRTDAQMAVISGLMG 710
S LEAYTGI+QGLKG V PD+ +V+P V I++F+ +A +ED TD +A +GL+G
Sbjct: 764 SCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAGLIG 823
Query: 711 DLTNAFGAHVLPMLDTK 761
DL AFG VL +++ +
Sbjct: 824 DLCTAFGKDVLKLVEAR 840
>BT009797-1|AAP88799.1| 876|Homo sapiens karyopherin (importin)
beta 1 protein.
Length = 876
Score = 124 bits (300), Expect = 3e-28
Identities = 55/84 (65%), Positives = 71/84 (84%)
Frame = +1
Query: 256 GLTGDICRALKNKMAPYCDEIIVLLLENLGDPSIHRSVKPEILSVFGDIALSIGSDFGKY 435
GL GD+CRAL++ + P+CDE++ LLLENLG+ ++HRSVKP+ILSVFGDIAL+IG +F KY
Sbjct: 672 GLVGDLCRALQSNIIPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDIALAIGGEFKKY 731
Query: 436 FDVVMQMLLQASNAQVDHNDYDMV 507
+VV+ L QAS AQVD +DYDMV
Sbjct: 732 LEVVLNTLQQASQAQVDKSDYDMV 755
Score = 107 bits (258), Expect = 3e-23
Identities = 55/81 (67%), Positives = 64/81 (79%)
Frame = +2
Query: 11 VLKKVTPDDAPQISDTIMTALLTVFASNAGKAGSVQEDALMAVSTLVEVLGEEFLKYMDT 190
VL+KV DA QISD +M +LL +F S AG +G VQEDALMAVSTLVEVLG EFLKYM+
Sbjct: 591 VLRKVQHQDALQISDVVMASLLRMFQSTAG-SGGVQEDALMAVSTLVEVLGGEFLKYMEA 649
Query: 191 FKKYLYTGLKNHQEYQVCIAA 253
FK +L GLKN+ EYQVC+AA
Sbjct: 650 FKPFLGIGLKNYAEYQVCLAA 670
Score = 82.2 bits (194), Expect = 2e-15
Identities = 37/77 (48%), Positives = 53/77 (68%)
Frame = +3
Query: 531 SVLEAYTGIIQGLKGVGSQVRPDIAIVEPHVPAIVNFMIQVANEEDRTDAQMAVISGLMG 710
S LEAYTGI+QGLKG V PD+ +V+P V I++F+ +A +ED TD +A +GL+G
Sbjct: 764 SCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAGLIG 823
Query: 711 DLTNAFGAHVLPMLDTK 761
DL AFG VL +++ +
Sbjct: 824 DLCTAFGKDVLKLVEAR 840
>BC036703-1|AAH36703.1| 876|Homo sapiens karyopherin (importin)
beta 1 protein.
Length = 876
Score = 124 bits (300), Expect = 3e-28
Identities = 55/84 (65%), Positives = 71/84 (84%)
Frame = +1
Query: 256 GLTGDICRALKNKMAPYCDEIIVLLLENLGDPSIHRSVKPEILSVFGDIALSIGSDFGKY 435
GL GD+CRAL++ + P+CDE++ LLLENLG+ ++HRSVKP+ILSVFGDIAL+IG +F KY
Sbjct: 672 GLVGDLCRALQSNIIPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDIALAIGGEFKKY 731
Query: 436 FDVVMQMLLQASNAQVDHNDYDMV 507
+VV+ L QAS AQVD +DYDMV
Sbjct: 732 LEVVLNTLQQASQAQVDKSDYDMV 755
Score = 107 bits (258), Expect = 3e-23
Identities = 55/81 (67%), Positives = 64/81 (79%)
Frame = +2
Query: 11 VLKKVTPDDAPQISDTIMTALLTVFASNAGKAGSVQEDALMAVSTLVEVLGEEFLKYMDT 190
VL+KV DA QISD +M +LL +F S AG +G VQEDALMAVSTLVEVLG EFLKYM+
Sbjct: 591 VLRKVQHQDALQISDVVMASLLRMFQSTAG-SGGVQEDALMAVSTLVEVLGGEFLKYMEA 649
Query: 191 FKKYLYTGLKNHQEYQVCIAA 253
FK +L GLKN+ EYQVC+AA
Sbjct: 650 FKPFLGIGLKNYAEYQVCLAA 670
Score = 82.2 bits (194), Expect = 2e-15
Identities = 37/77 (48%), Positives = 53/77 (68%)
Frame = +3
Query: 531 SVLEAYTGIIQGLKGVGSQVRPDIAIVEPHVPAIVNFMIQVANEEDRTDAQMAVISGLMG 710
S LEAYTGI+QGLKG V PD+ +V+P V I++F+ +A +ED TD +A +GL+G
Sbjct: 764 SCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAGLIG 823
Query: 711 DLTNAFGAHVLPMLDTK 761
DL AFG VL +++ +
Sbjct: 824 DLCTAFGKDVLKLVEAR 840
>BC024045-1|AAH24045.1| 876|Homo sapiens karyopherin (importin)
beta 1 protein.
Length = 876
Score = 124 bits (300), Expect = 3e-28
Identities = 55/84 (65%), Positives = 71/84 (84%)
Frame = +1
Query: 256 GLTGDICRALKNKMAPYCDEIIVLLLENLGDPSIHRSVKPEILSVFGDIALSIGSDFGKY 435
GL GD+CRAL++ + P+CDE++ LLLENLG+ ++HRSVKP+ILSVFGDIAL+IG +F KY
Sbjct: 672 GLVGDLCRALQSNIIPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDIALAIGGEFKKY 731
Query: 436 FDVVMQMLLQASNAQVDHNDYDMV 507
+VV+ L QAS AQVD +DYDMV
Sbjct: 732 LEVVLNTLQQASQAQVDKSDYDMV 755
Score = 107 bits (258), Expect = 3e-23
Identities = 55/81 (67%), Positives = 64/81 (79%)
Frame = +2
Query: 11 VLKKVTPDDAPQISDTIMTALLTVFASNAGKAGSVQEDALMAVSTLVEVLGEEFLKYMDT 190
VL+KV DA QISD +M +LL +F S AG +G VQEDALMAVSTLVEVLG EFLKYM+
Sbjct: 591 VLRKVQHQDALQISDVVMASLLRMFQSTAG-SGGVQEDALMAVSTLVEVLGGEFLKYMEA 649
Query: 191 FKKYLYTGLKNHQEYQVCIAA 253
FK +L GLKN+ EYQVC+AA
Sbjct: 650 FKPFLGIGLKNYAEYQVCLAA 670
Score = 82.2 bits (194), Expect = 2e-15
Identities = 37/77 (48%), Positives = 53/77 (68%)
Frame = +3
Query: 531 SVLEAYTGIIQGLKGVGSQVRPDIAIVEPHVPAIVNFMIQVANEEDRTDAQMAVISGLMG 710
S LEAYTGI+QGLKG V PD+ +V+P V I++F+ +A +ED TD +A +GL+G
Sbjct: 764 SCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAGLIG 823
Query: 711 DLTNAFGAHVLPMLDTK 761
DL AFG VL +++ +
Sbjct: 824 DLCTAFGKDVLKLVEAR 840
>BC003572-1|AAH03572.1| 876|Homo sapiens karyopherin (importin)
beta 1 protein.
Length = 876
Score = 124 bits (300), Expect = 3e-28
Identities = 55/84 (65%), Positives = 71/84 (84%)
Frame = +1
Query: 256 GLTGDICRALKNKMAPYCDEIIVLLLENLGDPSIHRSVKPEILSVFGDIALSIGSDFGKY 435
GL GD+CRAL++ + P+CDE++ LLLENLG+ ++HRSVKP+ILSVFGDIAL+IG +F KY
Sbjct: 672 GLVGDLCRALQSNIIPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDIALAIGGEFKKY 731
Query: 436 FDVVMQMLLQASNAQVDHNDYDMV 507
+VV+ L QAS AQVD +DYDMV
Sbjct: 732 LEVVLNTLQQASQAQVDKSDYDMV 755
Score = 107 bits (258), Expect = 3e-23
Identities = 55/81 (67%), Positives = 64/81 (79%)
Frame = +2
Query: 11 VLKKVTPDDAPQISDTIMTALLTVFASNAGKAGSVQEDALMAVSTLVEVLGEEFLKYMDT 190
VL+KV DA QISD +M +LL +F S AG +G VQEDALMAVSTLVEVLG EFLKYM+
Sbjct: 591 VLRKVQHQDALQISDVVMASLLRMFQSTAG-SGGVQEDALMAVSTLVEVLGGEFLKYMEA 649
Query: 191 FKKYLYTGLKNHQEYQVCIAA 253
FK +L GLKN+ EYQVC+AA
Sbjct: 650 FKPFLGIGLKNYAEYQVCLAA 670
Score = 82.2 bits (194), Expect = 2e-15
Identities = 37/77 (48%), Positives = 53/77 (68%)
Frame = +3
Query: 531 SVLEAYTGIIQGLKGVGSQVRPDIAIVEPHVPAIVNFMIQVANEEDRTDAQMAVISGLMG 710
S LEAYTGI+QGLKG V PD+ +V+P V I++F+ +A +ED TD +A +GL+G
Sbjct: 764 SCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAGLIG 823
Query: 711 DLTNAFGAHVLPMLDTK 761
DL AFG VL +++ +
Sbjct: 824 DLCTAFGKDVLKLVEAR 840
>X78712-1|CAA55365.1| 553|Homo sapiens glycerol kinase protein.
Length = 553
Score = 32.3 bits (70), Expect = 2.0
Identities = 17/68 (25%), Positives = 30/68 (44%)
Frame = +1
Query: 94 CWKSRQCSGGCSDGCFYSC*SLRRRVFKIHGYIQKIPLYWS*KPPGVPSLHCS*GLTGDI 273
C++ Q GCF C + R+ VF HG + + + P +L S + G +
Sbjct: 269 CFQEGQAKNTYGTGCFLLCNTGRKCVFSEHGLLTTVAYKLGREKPAYYALEGSVAIAGAV 328
Query: 274 CRALKNKM 297
R L++ +
Sbjct: 329 IRWLRDNL 336
>BC128152-1|AAI28153.1| 446|Homo sapiens AGBL1 protein protein.
Length = 446
Score = 32.3 bits (70), Expect = 2.0
Identities = 18/56 (32%), Positives = 29/56 (51%)
Frame = -3
Query: 415 QYSKQCLQIQIIFQASLIGELMDHLNSPITKLLSHHNRVPSYFSRRDRYHQSILSC 248
QY CL++ F+ L +L D LNS T+ +HH+ + S++ Y + SC
Sbjct: 2 QYEVMCLELSYSFE-ELQSKLGDDLNSEKTQYANHHHIPAAASSKQHCYSKDQSSC 56
>BC058888-1|AAH58888.1| 553|Homo sapiens glycerol kinase 2 protein.
Length = 553
Score = 32.3 bits (70), Expect = 2.0
Identities = 17/68 (25%), Positives = 30/68 (44%)
Frame = +1
Query: 94 CWKSRQCSGGCSDGCFYSC*SLRRRVFKIHGYIQKIPLYWS*KPPGVPSLHCS*GLTGDI 273
C++ Q GCF C + R+ VF HG + + + P +L S + G +
Sbjct: 269 CFQEGQAKNTYGTGCFLLCNTGRKCVFSEHGLLTTVAYKLGREKPAYYALEGSVAIAGAV 328
Query: 274 CRALKNKM 297
R L++ +
Sbjct: 329 IRWLRDNL 336
>BC048274-1|AAH48274.2| 553|Homo sapiens glycerol kinase 2 protein.
Length = 553
Score = 32.3 bits (70), Expect = 2.0
Identities = 17/68 (25%), Positives = 30/68 (44%)
Frame = +1
Query: 94 CWKSRQCSGGCSDGCFYSC*SLRRRVFKIHGYIQKIPLYWS*KPPGVPSLHCS*GLTGDI 273
C++ Q GCF C + R+ VF HG + + + P +L S + G +
Sbjct: 269 CFQEGQAKNTYGTGCFLLCNTGRKCVFSEHGLLTTVAYKLGREKPAYYALEGSVAIAGAV 328
Query: 274 CRALKNKM 297
R L++ +
Sbjct: 329 IRWLRDNL 336
>BC029820-1|AAH29820.1| 553|Homo sapiens glycerol kinase 2 protein.
Length = 553
Score = 32.3 bits (70), Expect = 2.0
Identities = 17/68 (25%), Positives = 30/68 (44%)
Frame = +1
Query: 94 CWKSRQCSGGCSDGCFYSC*SLRRRVFKIHGYIQKIPLYWS*KPPGVPSLHCS*GLTGDI 273
C++ Q GCF C + R+ VF HG + + + P +L S + G +
Sbjct: 269 CFQEGQAKNTYGTGCFLLCNTGRKCVFSEHGLLTTVAYKLGREKPAYYALEGSVAIAGAV 328
Query: 274 CRALKNKM 297
R L++ +
Sbjct: 329 IRWLRDNL 336
>AK056872-1|BAB71299.1| 478|Homo sapiens protein ( Homo sapiens
cDNA FLJ32310 fis, clone PROST2003102. ).
Length = 478
Score = 32.3 bits (70), Expect = 2.0
Identities = 18/56 (32%), Positives = 29/56 (51%)
Frame = -3
Query: 415 QYSKQCLQIQIIFQASLIGELMDHLNSPITKLLSHHNRVPSYFSRRDRYHQSILSC 248
QY CL++ F+ L +L D LNS T+ +HH+ + S++ Y + SC
Sbjct: 34 QYEVMCLELSYSFE-ELQSKLGDDLNSEKTQYANHHHIPAAASSKQHCYSKDQSSC 88
>CR457367-1|CAG33648.1| 757|Homo sapiens IPO4 protein.
Length = 757
Score = 30.7 bits (66), Expect = 6.1
Identities = 18/56 (32%), Positives = 30/56 (53%)
Frame = +1
Query: 292 KMAPYCDEIIVLLLENLGDPSIHRSVKPEILSVFGDIALSIGSDFGKYFDVVMQML 459
K+ PY E++ +L+ L +PS R+ K +S G IA + + YF +M+ L
Sbjct: 148 KVQPYLPELMECMLQLLRNPSSPRA-KELAVSALGAIATAAQASLLPYFPAIMEHL 202
>BC110804-1|AAI10805.1| 1081|Homo sapiens importin 4 protein.
Length = 1081
Score = 30.7 bits (66), Expect = 6.1
Identities = 18/56 (32%), Positives = 30/56 (53%)
Frame = +1
Query: 292 KMAPYCDEIIVLLLENLGDPSIHRSVKPEILSVFGDIALSIGSDFGKYFDVVMQML 459
K+ PY E++ +L+ L +PS R+ K +S G IA + + YF +M+ L
Sbjct: 472 KVQPYLPELMECMLQLLRNPSSPRA-KELAVSALGAIATAAQASLLPYFPAIMEHL 526
>BC003690-1|AAH03690.2| 787|Homo sapiens IPO4 protein protein.
Length = 787
Score = 30.7 bits (66), Expect = 6.1
Identities = 18/56 (32%), Positives = 30/56 (53%)
Frame = +1
Query: 292 KMAPYCDEIIVLLLENLGDPSIHRSVKPEILSVFGDIALSIGSDFGKYFDVVMQML 459
K+ PY E++ +L+ L +PS R+ K +S G IA + + YF +M+ L
Sbjct: 178 KVQPYLPELMECMLQLLRNPSSPRA-KELAVSALGAIATAAQASLLPYFPAIMEHL 232
>AB208897-1|BAD92134.1| 758|Homo sapiens IPO4 protein variant
protein.
Length = 758
Score = 30.7 bits (66), Expect = 6.1
Identities = 18/56 (32%), Positives = 30/56 (53%)
Frame = +1
Query: 292 KMAPYCDEIIVLLLENLGDPSIHRSVKPEILSVFGDIALSIGSDFGKYFDVVMQML 459
K+ PY E++ +L+ L +PS R+ K +S G IA + + YF +M+ L
Sbjct: 149 KVQPYLPELMECMLQLLRNPSSPRA-KELAVSALGAIATAAQASLLPYFPAIMEHL 203
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 104,357,692
Number of Sequences: 237096
Number of extensions: 2148669
Number of successful extensions: 5138
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 4666
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5136
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9478778060
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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