Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= e40h0726
(625 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_A7T6B8 Cluster: Predicted protein; n=1; Nematostella ve... 148 1e-34
UniRef50_Q4S0L0 Cluster: Malic enzyme; n=2; Tetraodon nigrovirid... 140 3e-32
UniRef50_Q5BX10 Cluster: Malic enzyme; n=1; Schistosoma japonicu... 137 2e-31
UniRef50_Q16798 Cluster: NADP-dependent malic enzyme, mitochondr... 137 2e-31
UniRef50_P48163 Cluster: NADP-dependent malic enzyme; n=63; Euka... 134 2e-30
UniRef50_A2ZQ54 Cluster: Malic enzyme; n=9; Oryza sativa|Rep: Ma... 132 7e-30
UniRef50_P06801 Cluster: NADP-dependent malic enzyme; n=52; cell... 132 7e-30
UniRef50_P23368 Cluster: NAD-dependent malic enzyme, mitochondri... 131 1e-29
UniRef50_Q89G76 Cluster: Malic enzyme; n=3; cellular organisms|R... 130 3e-29
UniRef50_A0L5P5 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 126 4e-28
UniRef50_A7CWP9 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 125 1e-27
UniRef50_P16243 Cluster: NADP-dependent malic enzyme, chloroplas... 124 1e-27
UniRef50_Q0AIF8 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 124 2e-27
UniRef50_A7PC00 Cluster: Chromosome chr2 scaffold_11, whole geno... 120 4e-26
UniRef50_Q86NT5 Cluster: Malic enzyme; n=2; Drosophila melanogas... 114 2e-24
UniRef50_Q8I8I4 Cluster: Malic enzyme; n=4; Eukaryota|Rep: Malic... 111 2e-23
UniRef50_A6SA55 Cluster: Malic enzyme; n=2; Sclerotiniaceae|Rep:... 107 2e-22
UniRef50_A7IMB8 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 107 2e-22
UniRef50_Q01AM5 Cluster: NADP+-dependent malic enzyme; n=2; Ostr... 107 3e-22
UniRef50_Q8D911 Cluster: NAD-dependent malic enzyme; n=187; cell... 107 3e-22
UniRef50_P37221 Cluster: NAD-dependent malic enzyme 62 kDa isofo... 105 7e-22
UniRef50_A3BK03 Cluster: Malic enzyme; n=2; Oryza sativa|Rep: Ma... 105 9e-22
UniRef50_UPI0000D9F768 Cluster: PREDICTED: similar to Y48B6A.12,... 103 3e-21
UniRef50_A2EKE3 Cluster: Malic enzyme; n=14; Trichomonadidae|Rep... 103 3e-21
UniRef50_Q4X1Z2 Cluster: NADP-dependent malic enzyme MaeA; n=11;... 103 3e-21
UniRef50_A3QW96 Cluster: Malic enzyme; n=10; Tigriopus californi... 102 6e-21
UniRef50_A1ZAF7 Cluster: Malic enzyme; n=5; Sophophora|Rep: Mali... 102 6e-21
UniRef50_P78715 Cluster: Malic enzyme, hydrogenosomal precursor;... 102 6e-21
UniRef50_Q016K2 Cluster: NADP dependent malic enzyme; n=2; Ostre... 101 1e-20
UniRef50_Q4PC56 Cluster: Malic enzyme; n=1; Ustilago maydis|Rep:... 100 2e-20
UniRef50_Q9HE50 Cluster: Malic enzyme; n=6; Pezizomycotina|Rep: ... 97 2e-19
UniRef50_Q875H8 Cluster: Malic enzyme; n=1; Mucor circinelloides... 95 9e-19
UniRef50_Q00XN9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 93 4e-18
UniRef50_Q4QAQ6 Cluster: Malic enzyme, putative; n=20; Trypanoso... 92 9e-18
UniRef50_Q5K758 Cluster: Malic enzyme; n=1; Filobasidiella neofo... 91 1e-17
UniRef50_A4RQC9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 90 5e-17
UniRef50_A0Q531 Cluster: NAD-dependent malic enzyme; n=10; Franc... 89 6e-17
UniRef50_A1SVL3 Cluster: Malic enzyme aka malate dehydrogenase (... 85 2e-15
UniRef50_A6XP71 Cluster: Malic enzyme protein 2; n=2; Mucoromyco... 84 3e-15
UniRef50_A4SKB8 Cluster: NAD-dependent malic enzyme; n=2; Aeromo... 83 5e-15
UniRef50_Q9RYN4 Cluster: Malate oxidoreductase; n=6; Deinococci|... 82 9e-15
UniRef50_Q5CS07 Cluster: Malic enzyme; n=2; Cryptosporidium|Rep:... 79 9e-14
UniRef50_Q95061 Cluster: Malic enzyme; n=2; Giardia intestinalis... 77 5e-13
UniRef50_Q7SHJ8 Cluster: Malic enzyme; n=12; Pezizomycotina|Rep:... 75 1e-12
UniRef50_P45868 Cluster: Probable NAD-dependent malic enzyme 2; ... 75 2e-12
UniRef50_A3YYQ0 Cluster: Malate oxidoreductase; n=1; Synechococc... 73 4e-12
UniRef50_Q6AL43 Cluster: Related to NAD-dependent malic enzyme; ... 72 1e-11
UniRef50_A2QY66 Cluster: Malic enzyme; n=2; cellular organisms|R... 68 2e-10
UniRef50_P40375 Cluster: NAD-dependent malic enzyme; n=3; Schizo... 65 1e-09
UniRef50_Q5KBK5 Cluster: Nad-dependent malic enzyme, putative; n... 61 2e-08
UniRef50_Q48796 Cluster: Malolactic enzyme; n=49; Bacteria|Rep: ... 60 3e-08
UniRef50_P36013 Cluster: NAD-dependent malic enzyme, mitochondri... 58 2e-07
UniRef50_A5C6I9 Cluster: Malic enzyme; n=1; Vitis vinifera|Rep: ... 57 4e-07
UniRef50_Q8Y5Y8 Cluster: Lmo1915 protein; n=15; Firmicutes|Rep: ... 56 5e-07
UniRef50_A4RZU1 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 56 5e-07
UniRef50_Q7K3R0 Cluster: Malic enzyme; n=2; Sophophora|Rep: Mali... 56 5e-07
UniRef50_Q2HCG7 Cluster: Malic enzyme; n=1; Chaetomium globosum|... 54 2e-06
UniRef50_Q8S484 Cluster: Putative NADP-dependent malic enzyme; n... 54 4e-06
UniRef50_Q5KEY3 Cluster: Malic enzyme; n=1; Filobasidiella neofo... 48 2e-04
UniRef50_Q9S4T5 Cluster: NAD-malate oxidoreductase homolog; n=15... 45 0.001
UniRef50_A5TVW2 Cluster: O-antigen N-acetylglucosamine transfera... 35 1.8
UniRef50_Q116W6 Cluster: Putative uncharacterized protein; n=1; ... 34 2.4
UniRef50_Q5SLE4 Cluster: CBS domain protein; n=7; Bacteria|Rep: ... 34 3.2
UniRef50_O31597 Cluster: YjbA protein; n=19; Bacillaceae|Rep: Yj... 34 3.2
UniRef50_Q18AX8 Cluster: Glycerol dehydratase; n=5; Clostridiace... 33 4.2
UniRef50_Q1EI20 Cluster: Putative uncharacterized protein; n=2; ... 33 7.3
UniRef50_A0WC26 Cluster: Multi-sensor hybrid histidine kinase pr... 33 7.3
UniRef50_Q7QFF8 Cluster: ENSANGP00000020727; n=1; Anopheles gamb... 33 7.3
UniRef50_A3GHR3 Cluster: Vacuolar diacylglycerol pyrophosphate p... 33 7.3
UniRef50_UPI0000EBCB21 Cluster: PREDICTED: similar to FELE-2, pa... 32 9.7
UniRef50_Q4T8X4 Cluster: Chromosome undetermined SCAF7707, whole... 32 9.7
UniRef50_Q2XQY7 Cluster: Intraflagellar transport protein 57; n=... 32 9.7
UniRef50_Q583W5 Cluster: Putative uncharacterized protein; n=2; ... 32 9.7
>UniRef50_A7T6B8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 365
Score = 148 bits (358), Expect = 1e-34
Identities = 61/81 (75%), Positives = 74/81 (91%)
Frame = +1
Query: 265 DNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVT 444
D E+MPIVYTPTVGLAC+K+G+++RRPRGLFI+IHDKGH+ D++ NWP T+V+AIV+T
Sbjct: 92 DYTEELMPIVYTPTVGLACRKYGMIFRRPRGLFISIHDKGHIRDIVSNWPTTEVKAIVMT 151
Query: 445 DGERILGLGDLGACGMGIPVG 507
DGERILGLGDLG CGMGIPVG
Sbjct: 152 DGERILGLGDLGCCGMGIPVG 172
Score = 67.7 bits (158), Expect = 2e-10
Identities = 30/50 (60%), Positives = 35/50 (70%)
Frame = +3
Query: 474 LGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
LG G P G+LALYT GGI P CLP+ IDVGTN + +LDDP YIG+
Sbjct: 162 LGCCGMGIPVGKLALYTVCGGIDPEGCLPVMIDVGTNNEELLDDPFYIGV 211
Score = 60.1 bits (139), Expect = 4e-08
Identities = 30/61 (49%), Positives = 36/61 (59%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F +LGIHGLLPP V +QE Q + + R N L KYI LM LL+RNE LF
Sbjct: 27 GLAFTLEERQILGIHGLLPPCVISQEIQAQRVYRELQRKPNDLEKYIQLMALLERNESLF 86
Query: 251 Y 253
+
Sbjct: 87 F 87
Score = 33.5 bits (73), Expect = 4.2
Identities = 15/30 (50%), Positives = 20/30 (66%)
Frame = +3
Query: 30 LSGLDHLKHPGLNKGMAFTIEERQSWGSTG 119
+ G D ++ LNKG+AFT+EERQ G G
Sbjct: 13 IRGTDIMRDSHLNKGLAFTLEERQILGIHG 42
>UniRef50_Q4S0L0 Cluster: Malic enzyme; n=2; Tetraodon
nigroviridis|Rep: Malic enzyme - Tetraodon nigroviridis
(Green puffer)
Length = 694
Score = 140 bits (338), Expect = 3e-32
Identities = 61/101 (60%), Positives = 78/101 (77%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
+ ++ + MPIVYTPTVGLACQ++GL +RRPRGLFITIHD+GH+ +L +WPE D++A+V
Sbjct: 137 LTSDIEKFMPIVYTPTVGLACQQYGLAFRRPRGLFITIHDRGHIATMLNSWPEEDIKAVV 196
Query: 439 VTDGERILGLGDLGACGMGIPVGNSRSTPRSEASSRISVCP 561
VTDGERILGLGDLG+ GMGIPVG R + +V P
Sbjct: 197 VTDGERILGLGDLGSYGMGIPVGKLALLHRLRRRAAAAVPP 237
Score = 56.8 bits (131), Expect = 4e-07
Identities = 30/61 (49%), Positives = 35/61 (57%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F +GIHGLLPP +Q+ QV S + NPL+KYI LM L DRNE LF
Sbjct: 74 GMAFTLEERLQMGIHGLLPPCFLSQDVQVLRVMKSYETRSNPLDKYILLMTLQDRNEKLF 133
Query: 251 Y 253
Y
Sbjct: 134 Y 134
Score = 36.3 bits (80), Expect = 0.60
Identities = 17/39 (43%), Positives = 23/39 (58%)
Frame = +3
Query: 3 SGDGQPTSGLSGLDHLKHPGLNKGMAFTIEERQSWGSTG 119
+ +G + G D ++P LNKGMAFT+EER G G
Sbjct: 51 ASEGSVRTKKRGYDITRNPHLNKGMAFTLEERLQMGIHG 89
>UniRef50_Q5BX10 Cluster: Malic enzyme; n=1; Schistosoma
japonicum|Rep: Malic enzyme - Schistosoma japonicum
(Blood fluke)
Length = 216
Score = 137 bits (331), Expect = 2e-31
Identities = 58/84 (69%), Positives = 73/84 (86%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
V ++V MP++YTPTVGLACQ++G+V+RRPRGL+ITIHD+ H+ ++L NWPE V+AIV
Sbjct: 129 VIEHVEYCMPLIYTPTVGLACQRYGVVFRRPRGLYITIHDRHHIPEILNNWPEPIVKAIV 188
Query: 439 VTDGERILGLGDLGACGMGIPVGN 510
TDGERILGLGDLGA GMGIP+GN
Sbjct: 189 FTDGERILGLGDLGAYGMGIPIGN 212
Score = 58.4 bits (135), Expect = 1e-07
Identities = 29/61 (47%), Positives = 35/61 (57%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F +LGIHGLLPP V T E+QV ++ + L +YIYL L DRNE LF
Sbjct: 66 GTAFTVNERQLLGIHGLLPPSVLTLEQQVSKMLANLKNMNDNLQRYIYLTSLQDRNEALF 125
Query: 251 Y 253
Y
Sbjct: 126 Y 126
>UniRef50_Q16798 Cluster: NADP-dependent malic enzyme, mitochondrial
precursor; n=15; Bilateria|Rep: NADP-dependent malic
enzyme, mitochondrial precursor - Homo sapiens (Human)
Length = 604
Score = 137 bits (331), Expect = 2e-31
Identities = 59/83 (71%), Positives = 71/83 (85%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
+ +V + MPIVYTPTVGLACQ +GL +RRPRGLFITIHDKGH+ +L +WPE +++A+V
Sbjct: 125 LTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKAVV 184
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTDGERILGLGDLG GMGIPVG
Sbjct: 185 VTDGERILGLGDLGCYGMGIPVG 207
Score = 70.9 bits (166), Expect = 2e-11
Identities = 31/50 (62%), Positives = 37/50 (74%)
Frame = +3
Query: 474 LGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
LG G P G+LALYTA GG+ P QCLP+ +DVGTN + +L DPLYIGL
Sbjct: 197 LGCYGMGIPVGKLALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGL 246
Score = 51.6 bits (118), Expect = 1e-05
Identities = 27/61 (44%), Positives = 35/61 (57%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F LGIHGL+PP +Q+ Q+ +R ++ L+KYI LM L DRNE LF
Sbjct: 62 GMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNEKLF 121
Query: 251 Y 253
Y
Sbjct: 122 Y 122
Score = 35.1 bits (77), Expect = 1.4
Identities = 16/28 (57%), Positives = 19/28 (67%)
Frame = +3
Query: 36 GLDHLKHPGLNKGMAFTIEERQSWGSTG 119
G D ++P LNKGMAFT+EER G G
Sbjct: 50 GYDVTRNPHLNKGMAFTLEERLQLGIHG 77
>UniRef50_P48163 Cluster: NADP-dependent malic enzyme; n=63;
Eukaryota|Rep: NADP-dependent malic enzyme - Homo
sapiens (Human)
Length = 572
Score = 134 bits (323), Expect = 2e-30
Identities = 58/83 (69%), Positives = 70/83 (84%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
+ ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+GH+ VL WPE ++AIV
Sbjct: 90 LTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASVLNAWPEDVIKAIV 149
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTDGERILGLGDLG GMGIPVG
Sbjct: 150 VTDGERILGLGDLGCNGMGIPVG 172
Score = 66.5 bits (155), Expect = 5e-10
Identities = 27/44 (61%), Positives = 34/44 (77%)
Frame = +3
Query: 492 GHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
G P G+LALYTA GG+ P +CLP+ +DVGT + +L DPLYIGL
Sbjct: 168 GIPVGKLALYTACGGMNPQECLPVILDVGTENEELLKDPLYIGL 211
Score = 48.4 bits (110), Expect = 1e-04
Identities = 23/50 (46%), Positives = 30/50 (60%)
Frame = +2
Query: 104 LGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFY 253
L IHGLLPP +QE QV + + + ++Y+ LM L DRNE LFY
Sbjct: 38 LNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFY 87
>UniRef50_A2ZQ54 Cluster: Malic enzyme; n=9; Oryza sativa|Rep: Malic
enzyme - Oryza sativa subsp. japonica (Rice)
Length = 613
Score = 132 bits (319), Expect = 7e-30
Identities = 55/81 (67%), Positives = 71/81 (87%)
Frame = +1
Query: 265 DNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVT 444
DNV E++P+VYTPTVG ACQK+G ++R+P+GL++++ DKG V DVL+NWPE +++ IVVT
Sbjct: 177 DNVEELLPVVYTPTVGEACQKYGSIFRQPQGLYVSLKDKGKVLDVLRNWPERNIQVIVVT 236
Query: 445 DGERILGLGDLGACGMGIPVG 507
DGERILGLGDLG GMGIPVG
Sbjct: 237 DGERILGLGDLGCQGMGIPVG 257
Score = 70.1 bits (164), Expect = 4e-11
Identities = 31/50 (62%), Positives = 38/50 (76%)
Frame = +3
Query: 474 LGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
LG G P G+L+LYTALGG++P CLPITIDVGTN + +L+D YIGL
Sbjct: 247 LGCQGMGIPVGKLSLYTALGGVRPSACLPITIDVGTNNEQLLNDEFYIGL 296
Score = 48.8 bits (111), Expect = 1e-04
Identities = 23/61 (37%), Positives = 35/61 (57%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F + + GLLPP V +Q+ QV+ ++ +Y PL +Y+ +M L +RNE LF
Sbjct: 112 GLAFSEKERDAHYLRGLLPPAVVSQDLQVKKIMHNLRQYSVPLQRYMAMMDLQERNERLF 171
Query: 251 Y 253
Y
Sbjct: 172 Y 172
>UniRef50_P06801 Cluster: NADP-dependent malic enzyme; n=52;
cellular organisms|Rep: NADP-dependent malic enzyme -
Mus musculus (Mouse)
Length = 572
Score = 132 bits (319), Expect = 7e-30
Identities = 59/80 (73%), Positives = 68/80 (85%)
Frame = +1
Query: 268 NVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTD 447
+V + MPIVYTPTVGLACQ++ L +R+PRGLFI+IHDKGH+ VL WPE V+AIVVTD
Sbjct: 93 DVEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDKGHIASVLNAWPEDVVKAIVVTD 152
Query: 448 GERILGLGDLGACGMGIPVG 507
GERILGLGDLG GMGIPVG
Sbjct: 153 GERILGLGDLGCNGMGIPVG 172
Score = 71.3 bits (167), Expect = 2e-11
Identities = 30/44 (68%), Positives = 35/44 (79%)
Frame = +3
Query: 492 GHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
G P G+LALYTA GG+ P QCLPIT+DVGT + +L DPLYIGL
Sbjct: 168 GIPVGKLALYTACGGVNPQQCLPITLDVGTENEELLKDPLYIGL 211
Score = 49.6 bits (113), Expect = 6e-05
Identities = 24/50 (48%), Positives = 32/50 (64%)
Frame = +2
Query: 104 LGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFY 253
L IHGLLPP + +QE QV + +R + ++Y+ LM L DRNE LFY
Sbjct: 38 LNIHGLLPPCIISQELQVLRIIKNFERLNSDFDRYLLLMDLQDRNEKLFY 87
>UniRef50_P23368 Cluster: NAD-dependent malic enzyme, mitochondrial
precursor; n=53; Eumetazoa|Rep: NAD-dependent malic
enzyme, mitochondrial precursor - Homo sapiens (Human)
Length = 584
Score = 131 bits (317), Expect = 1e-29
Identities = 55/81 (67%), Positives = 69/81 (85%)
Frame = +1
Query: 265 DNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVT 444
D++ +MPIVYTPTVGLAC ++G ++RRP+GLFI+I D+GHV ++ NWPE V+A+VVT
Sbjct: 102 DDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKAVVVT 161
Query: 445 DGERILGLGDLGACGMGIPVG 507
DGERILGLGDLG GMGIPVG
Sbjct: 162 DGERILGLGDLGVYGMGIPVG 182
Score = 60.9 bits (141), Expect = 2e-08
Identities = 26/61 (42%), Positives = 40/61 (65%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F + +LG+ GLLPP+++TQ+ Q ++ + +PL KYIY+MG+ +RNE LF
Sbjct: 37 GMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQERNEKLF 96
Query: 251 Y 253
Y
Sbjct: 97 Y 97
Score = 60.9 bits (141), Expect = 2e-08
Identities = 27/50 (54%), Positives = 35/50 (70%)
Frame = +3
Query: 474 LGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
LG G P G+L LYTA GI+P +CLP+ IDVGT+ ++L DP Y+GL
Sbjct: 172 LGVYGMGIPVGKLCLYTACAGIRPDRCLPVCIDVGTDNIALLKDPFYMGL 221
>UniRef50_Q89G76 Cluster: Malic enzyme; n=3; cellular organisms|Rep:
Malic enzyme - Bradyrhizobium japonicum
Length = 531
Score = 130 bits (313), Expect = 3e-29
Identities = 57/83 (68%), Positives = 70/83 (84%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
V DN+ E+ PI+YTPTVGLACQK+GL+++RPRG+FI+ D+G + ++LKNWP R IV
Sbjct: 75 VVDNIDEIQPIIYTPTVGLACQKYGLIFQRPRGMFISSRDRGQIAEILKNWP-YPARLIV 133
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTDGERILGLGDLGA GMGIPVG
Sbjct: 134 VTDGERILGLGDLGANGMGIPVG 156
Score = 62.9 bits (146), Expect = 6e-09
Identities = 26/50 (52%), Positives = 35/50 (70%)
Frame = +3
Query: 474 LGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
LG G P G+L+LY+A G+ P CLPI +DVGTN + +L+DP Y+GL
Sbjct: 146 LGANGMGIPVGKLSLYSACAGVHPEHCLPIVLDVGTNNEELLNDPYYLGL 195
Score = 48.4 bits (110), Expect = 1e-04
Identities = 25/61 (40%), Positives = 32/61 (52%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F + LG+ GLLPP V T E QV+ ++ L KY+ L L DRNE LF
Sbjct: 12 GTAFTEAERAALGLRGLLPPCVLTMETQVDRVLTNLRMLPTDLEKYVALNALHDRNEALF 71
Query: 251 Y 253
+
Sbjct: 72 F 72
>UniRef50_A0L5P5 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=1;
Magnetococcus sp. MC-1|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Magnetococcus
sp. (strain MC-1)
Length = 556
Score = 126 bits (304), Expect = 4e-28
Identities = 55/83 (66%), Positives = 68/83 (81%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
V N+ EM+PI+YTPTVG ACQ +G ++RRP+G+FI+I+DKG + ++L NW DVR IV
Sbjct: 94 VMTNIEEMLPIIYTPTVGKACQTYGHIFRRPQGMFISINDKGRIAELLGNWVHKDVRVIV 153
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTDG RILGLGDLGA GMGIPVG
Sbjct: 154 VTDGSRILGLGDLGAHGMGIPVG 176
Score = 67.7 bits (158), Expect = 2e-10
Identities = 29/50 (58%), Positives = 38/50 (76%)
Frame = +3
Query: 474 LGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
LG G P G+LALYTAL GI P CLP+T+D+GTN +++ +DPLY+GL
Sbjct: 166 LGAHGMGIPVGKLALYTALAGIPPIHCLPVTLDMGTNNEALRNDPLYVGL 215
Score = 51.2 bits (117), Expect = 2e-05
Identities = 26/61 (42%), Positives = 33/61 (54%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F + + GLLPPRV+T E Q+ + N L KYI+L GL +RNE LF
Sbjct: 31 GVAFTEEERDLFHLRGLLPPRVQTMEAQLGRALDNFRCKPNDLEKYIFLTGLQERNETLF 90
Query: 251 Y 253
Y
Sbjct: 91 Y 91
>UniRef50_A7CWP9 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=1;
Opitutaceae bacterium TAV2|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Opitutaceae
bacterium TAV2
Length = 561
Score = 125 bits (301), Expect = 1e-27
Identities = 54/83 (65%), Positives = 69/83 (83%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
+ ++ EM+P+VYTPTVG AC ++G +RRPRGLFI+I D+G + ++L++WP TDVR IV
Sbjct: 99 LTNHAEEMIPLVYTPTVGQACLEYGANFRRPRGLFISIKDRGRIAEILRHWPITDVRMIV 158
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTDGERILGLGDLG GMGIPVG
Sbjct: 159 VTDGERILGLGDLGVLGMGIPVG 181
Score = 56.0 bits (129), Expect = 7e-07
Identities = 23/49 (46%), Positives = 34/49 (69%)
Frame = +3
Query: 474 LGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 620
LG + G P G+LALY+A G+ P CLPI +D G + +++ +DPLY+G
Sbjct: 171 LGVLGMGIPVGKLALYSACAGLHPSYCLPIALDAGIDNETLRNDPLYLG 219
Score = 54.0 bits (124), Expect = 3e-06
Identities = 27/61 (44%), Positives = 35/61 (57%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F R LG+ GLLPPRV T E+Q + ++ + + + KYIYL L RNE LF
Sbjct: 36 GTAFSERERDALGLRGLLPPRVFTLEQQEQRALNAMAKKPSAIEKYIYLTTLQSRNETLF 95
Query: 251 Y 253
Y
Sbjct: 96 Y 96
>UniRef50_P16243 Cluster: NADP-dependent malic enzyme, chloroplast
precursor; n=79; Magnoliophyta|Rep: NADP-dependent malic
enzyme, chloroplast precursor - Zea mays (Maize)
Length = 636
Score = 124 bits (300), Expect = 1e-27
Identities = 52/81 (64%), Positives = 67/81 (82%)
Frame = +1
Query: 265 DNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVT 444
DNV E++P VYTPTVG ACQK+G ++ RP+GL++++ DKG V +VL+NWP +++ I VT
Sbjct: 174 DNVVELLPFVYTPTVGEACQKYGSIFGRPQGLYVSLKDKGKVLEVLRNWPHRNIQVICVT 233
Query: 445 DGERILGLGDLGACGMGIPVG 507
DGERILGLGDLG GMGIPVG
Sbjct: 234 DGERILGLGDLGCQGMGIPVG 254
Score = 68.9 bits (161), Expect = 9e-11
Identities = 32/50 (64%), Positives = 37/50 (74%)
Frame = +3
Query: 474 LGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
LG G P G+LALYTALGG+ P CLPITIDVGTN + +L+D YIGL
Sbjct: 244 LGCQGMGIPVGKLALYTALGGVDPSVCLPITIDVGTNNEFLLNDEFYIGL 293
Score = 46.8 bits (106), Expect = 4e-04
Identities = 20/48 (41%), Positives = 32/48 (66%)
Frame = +2
Query: 110 IHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFY 253
+ GLLPP V +QE Q++ ++ +Y+ PL +YI +M L + +E LFY
Sbjct: 122 LRGLLPPAVLSQELQIKKFMNTLRQYQTPLQRYIAMMNLQETDERLFY 169
>UniRef50_Q0AIF8 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=2;
Nitrosomonas|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Nitrosomonas
eutropha (strain C71)
Length = 536
Score = 124 bits (298), Expect = 2e-27
Identities = 53/83 (63%), Positives = 67/83 (80%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
+ D++ E+MP+VYTPTVG AC K ++R+P+G +IT D+G + LKNWPETDV+ IV
Sbjct: 81 LVDHIGEIMPLVYTPTVGEACVKLSHIFRKPQGFYITPEDRGEIISRLKNWPETDVQIIV 140
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTDGERILGLGDLGA GMGIP+G
Sbjct: 141 VTDGERILGLGDLGANGMGIPIG 163
Score = 57.6 bits (133), Expect = 2e-07
Identities = 23/49 (46%), Positives = 34/49 (69%)
Frame = +3
Query: 474 LGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 620
LG G P G+++LY A GI P +C+P+ +DVGT Q++ +DPLY+G
Sbjct: 153 LGANGMGIPIGKISLYVACAGIYPDRCMPVMLDVGTGNQALREDPLYLG 201
Score = 39.5 bits (88), Expect = 0.064
Identities = 19/49 (38%), Positives = 29/49 (59%)
Frame = +2
Query: 107 GIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFY 253
G+ GLLP V ++Q + ++ + + KYIYL LL+RN+ LFY
Sbjct: 30 GLQGLLPYGVTDIKKQQQRVLANLRNKSSNIEKYIYLNDLLERNQQLFY 78
>UniRef50_A7PC00 Cluster: Chromosome chr2 scaffold_11, whole genome
shotgun sequence; n=3; Vitis vinifera|Rep: Chromosome
chr2 scaffold_11, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 573
Score = 120 bits (288), Expect = 4e-26
Identities = 52/81 (64%), Positives = 65/81 (80%)
Frame = +1
Query: 265 DNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVT 444
DNV E++P+VYTPTVG ACQK+G ++RRP+ L+I G + +VLKNWPE ++ IVVT
Sbjct: 274 DNVEELLPVVYTPTVGEACQKYGSIFRRPQSLYIIDFFMGKILEVLKNWPERSIQVIVVT 333
Query: 445 DGERILGLGDLGACGMGIPVG 507
+GERILGLGDLG GMGIPVG
Sbjct: 334 NGERILGLGDLGCQGMGIPVG 354
Score = 65.3 bits (152), Expect = 1e-09
Identities = 29/50 (58%), Positives = 35/50 (70%)
Frame = +3
Query: 474 LGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
LG G P G+L+LYT LGG+ P CLP+TIDVGTN + +L D YIGL
Sbjct: 344 LGCQGMGIPVGKLSLYTTLGGLHPSVCLPVTIDVGTNNEQLLKDEFYIGL 393
Score = 44.8 bits (101), Expect = 0.002
Identities = 21/61 (34%), Positives = 33/61 (54%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F + + GLLPP V Q+ Q + ++ +Y+ PL +Y+ +M +RNE LF
Sbjct: 209 GLAFTEKERDAHYLRGLLPPAVLNQDLQEKRLMHNLRQYKVPLQRYMAMMDFQERNERLF 268
Query: 251 Y 253
Y
Sbjct: 269 Y 269
>UniRef50_Q86NT5 Cluster: Malic enzyme; n=2; Drosophila
melanogaster|Rep: Malic enzyme - Drosophila melanogaster
(Fruit fly)
Length = 610
Score = 114 bits (274), Expect = 2e-24
Identities = 52/85 (61%), Positives = 65/85 (76%), Gaps = 1/85 (1%)
Frame = +1
Query: 256 FVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWP-ETDVRA 432
FV+ NV ++PI+YTPTVGLAC +G++YR G+ IT HD+GH+ +L NWP V+A
Sbjct: 120 FVSKNVHAVLPIIYTPTVGLACTVYGMLYRGMTGIHITKHDRGHMKQILSNWPMRRSVKA 179
Query: 433 IVVTDGERILGLGDLGACGMGIPVG 507
I VTDG+RILGLGDLGA GMGI VG
Sbjct: 180 ICVTDGQRILGLGDLGANGMGIAVG 204
Score = 59.3 bits (137), Expect = 7e-08
Identities = 30/63 (47%), Positives = 37/63 (58%)
Frame = +3
Query: 435 CCNRRRTYSGSWRLGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLY 614
C + G LG G G++ LYTAL GI P LPI +DVGTN +S+ +DPLY
Sbjct: 181 CVTDGQRILGLGDLGANGMGIAVGKMELYTALAGIPPSMLLPICLDVGTNNKSLHEDPLY 240
Query: 615 IGL 623
IGL
Sbjct: 241 IGL 243
Score = 36.7 bits (81), Expect = 0.45
Identities = 17/50 (34%), Positives = 29/50 (58%)
Frame = +2
Query: 104 LGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFY 253
L IHGL+P V+T +EQ+ + + +E+ + +Y YL L E L++
Sbjct: 69 LCIHGLMPACVRTYDEQMLAIESNFHSFESNVGRYRYLRALRQGYERLYF 118
>UniRef50_Q8I8I4 Cluster: Malic enzyme; n=4; Eukaryota|Rep: Malic
enzyme - Mastigamoeba balamuthi (Phreatamoeba balamuthi)
Length = 568
Score = 111 bits (266), Expect = 2e-23
Identities = 51/83 (61%), Positives = 62/83 (74%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
V +V E +P+VYTPTVG C KF +R P GL+IT DKGHV ++L+NWP +V IV
Sbjct: 110 VQHHVEECVPLVYTPTVGEGCTKFSAEFRNPTGLYITPEDKGHVAEILENWPH-EVEIIV 168
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTDG RILGLGDLG+ GMGIP+G
Sbjct: 169 VTDGGRILGLGDLGSNGMGIPIG 191
Score = 59.7 bits (138), Expect = 6e-08
Identities = 26/50 (52%), Positives = 34/50 (68%)
Frame = +3
Query: 474 LGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
LG G P G+L LY A G +P + LP+ IDVGTN Q +LDDP+Y+G+
Sbjct: 181 LGSNGMGIPIGKLHLYIACAGFRPDRTLPVMIDVGTNRQELLDDPMYLGV 230
Score = 41.5 bits (93), Expect = 0.016
Identities = 23/61 (37%), Positives = 28/61 (45%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F L I GLLP V+T E Q + PL KY+YL L RN+ LF
Sbjct: 47 GTAFTTEERKALRIRGLLPHAVETIEAQAARAYAQLTSQPTPLLKYLYLSQLSQRNQTLF 106
Query: 251 Y 253
+
Sbjct: 107 F 107
>UniRef50_A6SA55 Cluster: Malic enzyme; n=2; Sclerotiniaceae|Rep:
Malic enzyme - Botryotinia fuckeliana B05.10
Length = 685
Score = 107 bits (258), Expect = 2e-22
Identities = 44/83 (53%), Positives = 65/83 (78%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
V +++ ++ P++YTPTVG AC ++ +Y++P GL+++ HD+G++ +VL NW ++DV V
Sbjct: 165 VQEHLTDITPLIYTPTVGEACLRWSEIYQQPEGLYLSYHDRGNLEEVLGNWRQSDVEMTV 224
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTDG RILGLGDLG GMGIPVG
Sbjct: 225 VTDGSRILGLGDLGVNGMGIPVG 247
Score = 57.6 bits (133), Expect = 2e-07
Identities = 24/43 (55%), Positives = 31/43 (72%)
Frame = +3
Query: 492 GHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 620
G P G+L+LYT GI P + LPIT+D+GTN + L DPLY+G
Sbjct: 243 GIPVGKLSLYTGCAGIHPSKTLPITLDLGTNNEKFLKDPLYMG 285
Score = 44.8 bits (101), Expect = 0.002
Identities = 18/46 (39%), Positives = 28/46 (60%)
Frame = +2
Query: 116 GLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFY 253
GL+PP V++ + Q C ++ + P+ KY+YL L + N HLFY
Sbjct: 117 GLVPPNVESHKLQTTRCLQQLNAKKTPIEKYMYLSNLRNNNVHLFY 162
>UniRef50_A7IMB8 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=2;
Alphaproteobacteria|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Xanthobacter
sp. (strain Py2)
Length = 550
Score = 107 bits (257), Expect = 2e-22
Identities = 46/83 (55%), Positives = 62/83 (74%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
V + +PI+Y PTV AC+ FG +YRRPRG++IT H KG + +VL+NWP+ D+R +
Sbjct: 94 VMSDPKRFIPILYDPTVADACEAFGNLYRRPRGMYITRHMKGRMAEVLRNWPQKDIRFVC 153
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
V+ G RILGLGD+GA GMGIP+G
Sbjct: 154 VSTGGRILGLGDIGANGMGIPIG 176
Score = 46.4 bits (105), Expect = 6e-04
Identities = 23/50 (46%), Positives = 32/50 (64%)
Frame = +2
Query: 104 LGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFY 253
LG+ GLLP V+T + QVE +D ++ L++Y YLM L RNE +FY
Sbjct: 42 LGLEGLLPHAVETLDRQVERVLDHLDHVKDELDQYSYLMDLEARNETVFY 91
Score = 46.0 bits (104), Expect = 7e-04
Identities = 18/43 (41%), Positives = 26/43 (60%)
Frame = +3
Query: 492 GHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 620
G P G+L LYTA + P LP+ D+GT+ + + DP Y+G
Sbjct: 172 GIPIGKLQLYTACAAVPPDVLLPVLFDIGTSNEHLRADPFYLG 214
Score = 34.7 bits (76), Expect = 1.8
Identities = 17/38 (44%), Positives = 22/38 (57%)
Frame = +3
Query: 18 PTSGLSGLDHLKHPGLNKGMAFTIEERQSWGSTGCYHH 131
P S LSGL+ L P NKG A+T ++R+ G G H
Sbjct: 13 PKSNLSGLNLLHDPVRNKGTAYTRDDRRQLGLEGLLPH 50
>UniRef50_Q01AM5 Cluster: NADP+-dependent malic enzyme; n=2;
Ostreococcus|Rep: NADP+-dependent malic enzyme -
Ostreococcus tauri
Length = 580
Score = 107 bits (256), Expect = 3e-22
Identities = 46/78 (58%), Positives = 61/78 (78%)
Frame = +1
Query: 280 MMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERI 459
++PI+YTPTVG AC KFG + +RP GL+++ +D G+V +++NWP TDV+ V+TDGERI
Sbjct: 128 LLPILYTPTVGEACVKFGTLVQRPMGLWVSSNDAGNVKQLIRNWPATDVKIAVITDGERI 187
Query: 460 LGLGDLGACGMGIPVGNS 513
LGLGD GA GMGI G S
Sbjct: 188 LGLGDQGANGMGISAGKS 205
Score = 50.0 bits (114), Expect = 5e-05
Identities = 23/44 (52%), Positives = 29/44 (65%)
Frame = +3
Query: 492 GHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
G G+ +Y A G + P LPI +D GTN Q++LDDPLYIGL
Sbjct: 199 GISAGKSMVYAACG-VPPSALLPIQVDTGTNNQTLLDDPLYIGL 241
>UniRef50_Q8D911 Cluster: NAD-dependent malic enzyme; n=187;
cellular organisms|Rep: NAD-dependent malic enzyme -
Vibrio vulnificus
Length = 562
Score = 107 bits (256), Expect = 3e-22
Identities = 47/83 (56%), Positives = 62/83 (74%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
V +++ EMMPI+YTPTVG AC+ F +YRR RGLF++ ++ + D+L N +V+ IV
Sbjct: 89 VQNHITEMMPIIYTPTVGAACENFSNIYRRGRGLFVSYANRDRIDDILNNASNHNVKVIV 148
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTDGERILGLGD G GMGIP+G
Sbjct: 149 VTDGERILGLGDQGIGGMGIPIG 171
Score = 57.2 bits (132), Expect = 3e-07
Identities = 25/43 (58%), Positives = 30/43 (69%)
Frame = +3
Query: 492 GHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 620
G P G+L+LYTA GGI P LPI +DVGTN L DP+Y+G
Sbjct: 167 GIPIGKLSLYTACGGISPAYTLPIVLDVGTNNPQRLADPMYMG 209
Score = 46.0 bits (104), Expect = 7e-04
Identities = 22/61 (36%), Positives = 32/61 (52%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F + GLLP +T +EQVE + +E+ ++K+IYL + D NE LF
Sbjct: 26 GSAFSAEERISFNLEGLLPETTETIQEQVERAYMQYKAFESDMDKHIYLRNIQDTNETLF 85
Query: 251 Y 253
Y
Sbjct: 86 Y 86
>UniRef50_P37221 Cluster: NAD-dependent malic enzyme 62 kDa isoform,
mitochondrial precursor; n=41; Eukaryota|Rep:
NAD-dependent malic enzyme 62 kDa isoform, mitochondrial
precursor - Solanum tuberosum (Potato)
Length = 626
Score = 105 bits (253), Expect = 7e-22
Identities = 45/81 (55%), Positives = 59/81 (72%)
Frame = +1
Query: 265 DNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVT 444
+N+ E PIVYTPTVGL CQK+ ++RRPRG++ + D+G + ++ NWP V IVVT
Sbjct: 136 ENIEEYAPIVYTPTVGLVCQKYSGLFRRPRGMYFSAEDRGEMMSMVYNWPADQVDMIVVT 195
Query: 445 DGERILGLGDLGACGMGIPVG 507
DG RILGLGDLG G+GI +G
Sbjct: 196 DGSRILGLGDLGIQGIGIAIG 216
Score = 54.8 bits (126), Expect = 2e-06
Identities = 25/50 (50%), Positives = 33/50 (66%)
Frame = +3
Query: 474 LGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
LG G G+L LY A GI P + LP+ IDVGT+ +++L DPLY+GL
Sbjct: 206 LGIQGIGIAIGKLDLYVAAAGINPQRVLPVMIDVGTDNENLLKDPLYLGL 255
Score = 33.9 bits (74), Expect = 3.2
Identities = 24/71 (33%), Positives = 34/71 (47%), Gaps = 10/71 (14%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQV-----ELCKLSIDRYENPLNKYI-----YLM 220
G F L I GLLPP V + E+Q+ +L +L + + P + Y+ L
Sbjct: 61 GTAFSFTERDRLHIRGLLPPNVMSFEQQIARFMADLKRLEVQARDGPSDPYVLAKWRILN 120
Query: 221 GLLDRNEHLFY 253
L DRNE L+Y
Sbjct: 121 RLHDRNETLYY 131
>UniRef50_A3BK03 Cluster: Malic enzyme; n=2; Oryza sativa|Rep: Malic
enzyme - Oryza sativa subsp. japonica (Rice)
Length = 635
Score = 105 bits (252), Expect = 9e-22
Identities = 45/81 (55%), Positives = 58/81 (71%)
Frame = +1
Query: 265 DNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVT 444
DN+ E PIVYTPTVGL CQ + ++RRPRG++ + D+G + ++ NWP V IVVT
Sbjct: 170 DNIEEHAPIVYTPTVGLVCQNYSGLFRRPRGMYFSAEDRGEMMSMVYNWPADQVDMIVVT 229
Query: 445 DGERILGLGDLGACGMGIPVG 507
DG RILGLGDLG G+GI +G
Sbjct: 230 DGSRILGLGDLGVHGIGIAIG 250
Score = 55.6 bits (128), Expect = 9e-07
Identities = 24/44 (54%), Positives = 30/44 (68%)
Frame = +3
Query: 492 GHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
G G+L LY A GI P + LP+ IDVGTN + +L DPLY+GL
Sbjct: 246 GIAIGKLDLYVAAAGINPQRVLPVMIDVGTNNEKLLKDPLYLGL 289
>UniRef50_UPI0000D9F768 Cluster: PREDICTED: similar to Y48B6A.12,
partial; n=1; Macaca mulatta|Rep: PREDICTED: similar to
Y48B6A.12, partial - Macaca mulatta
Length = 456
Score = 103 bits (248), Expect = 3e-21
Identities = 48/83 (57%), Positives = 60/83 (72%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
+ D+VAEMMPIVYTP VG ACQ FG ++R RGL+ + +KG+ +++ N D IV
Sbjct: 82 LVDHVAEMMPIVYTPVVGKACQLFGHIFRNARGLYFNLSEKGNFKEMVWNSNVRDADIIV 141
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTDG RILGLGDLG GMGIP+G
Sbjct: 142 VTDGSRILGLGDLGTNGMGIPIG 164
Score = 54.4 bits (125), Expect = 2e-06
Identities = 23/49 (46%), Positives = 33/49 (67%)
Frame = +3
Query: 474 LGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 620
LG G P G+L+LY A GI P + +P+T+DVGTN +L+D +Y+G
Sbjct: 154 LGTNGMGIPIGKLSLYVACAGINPGRTVPVTLDVGTNNPDLLNDDMYLG 202
Score = 45.6 bits (103), Expect = 0.001
Identities = 21/46 (45%), Positives = 27/46 (58%)
Frame = +2
Query: 116 GLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFY 253
GLLPP+V + Q C L + N + KYIYL L DRNE L++
Sbjct: 34 GLLPPKVLDLDVQSRRCYLQFSQNSNDIEKYIYLESLHDRNETLYF 79
>UniRef50_A2EKE3 Cluster: Malic enzyme; n=14; Trichomonadidae|Rep:
Malic enzyme - Trichomonas vaginalis G3
Length = 567
Score = 103 bits (248), Expect = 3e-21
Identities = 47/77 (61%), Positives = 58/77 (75%)
Frame = +1
Query: 277 EMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGER 456
E MPI+YTPTVG ACQK+ + RG++IT D G + D+L+N+P D+R IVVTD R
Sbjct: 106 ETMPILYTPTVGEACQKWATHRQSYRGIYITPEDSGKIKDILRNYPRQDIRCIVVTDAGR 165
Query: 457 ILGLGDLGACGMGIPVG 507
ILGLGDLGA G+GIPVG
Sbjct: 166 ILGLGDLGASGLGIPVG 182
Score = 51.6 bits (118), Expect = 1e-05
Identities = 23/49 (46%), Positives = 32/49 (65%)
Frame = +3
Query: 474 LGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 620
LG G P G+L LYT +G + P Q LP+ +D+GT+ + +L DPLY G
Sbjct: 172 LGASGLGIPVGKLMLYTLIGQVDPDQTLPVQLDMGTDRKEILADPLYHG 220
Score = 35.9 bits (79), Expect = 0.79
Identities = 18/61 (29%), Positives = 28/61 (45%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F + GLLP +V T++EQ + + PL KYI+L ++N F
Sbjct: 36 GTAFTKEERDRFNLRGLLPYKVFTKDEQAARIRRQFELMPTPLLKYIFLANEREKNSQSF 95
Query: 251 Y 253
+
Sbjct: 96 W 96
>UniRef50_Q4X1Z2 Cluster: NADP-dependent malic enzyme MaeA; n=11;
Pezizomycotina|Rep: NADP-dependent malic enzyme MaeA -
Aspergillus fumigatus (Sartorya fumigata)
Length = 661
Score = 103 bits (248), Expect = 3e-21
Identities = 41/83 (49%), Positives = 62/83 (74%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
V D++ E+ P++YTP VG ACQK+ +Y++P G++++ D+G++ V+ NWP+ +V
Sbjct: 157 VTDHLKELTPLIYTPVVGEACQKWSEIYQQPEGMYLSWEDRGNLAAVIANWPQPNVEITC 216
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
+TDG RILGLGDLG GMGIP+G
Sbjct: 217 ITDGSRILGLGDLGINGMGIPIG 239
Score = 58.0 bits (134), Expect = 2e-07
Identities = 23/43 (53%), Positives = 34/43 (79%)
Frame = +3
Query: 492 GHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 620
G P G+LALYTA GI+P LP+T+D+GT+ +++ +DPLY+G
Sbjct: 235 GIPIGKLALYTACAGIRPEATLPLTLDLGTSNKALREDPLYMG 277
Score = 39.5 bits (88), Expect = 0.064
Identities = 18/50 (36%), Positives = 27/50 (54%)
Frame = +2
Query: 104 LGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFY 253
L +GL PPR ++ E Q C + + ++K++YL L N HLFY
Sbjct: 105 LRTYGLTPPRAESYEIQKTRCLAQLALKQTAIDKFLYLSTLRKNNVHLFY 154
>UniRef50_A3QW96 Cluster: Malic enzyme; n=10; Tigriopus
californicus|Rep: Malic enzyme - Tigriopus californicus
(Marine copepod)
Length = 322
Score = 102 bits (245), Expect = 6e-21
Identities = 43/81 (53%), Positives = 58/81 (71%)
Frame = +1
Query: 265 DNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVT 444
DN +M PI+YTPTVG AC F +YRRPRG++ + D+G + ++ NW +V A+V+T
Sbjct: 141 DNFQDMAPIIYTPTVGWACSHFSQLYRRPRGMYFSHGDRGEMASMVYNWESDEVDAVVIT 200
Query: 445 DGERILGLGDLGACGMGIPVG 507
DG RILGLGDLG G+GI +G
Sbjct: 201 DGSRILGLGDLGLGGLGISIG 221
Score = 54.4 bits (125), Expect = 2e-06
Identities = 22/44 (50%), Positives = 30/44 (68%)
Frame = +3
Query: 492 GHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
G G+L LY A GG P + LP+ +D+GTN Q +L+DP Y+GL
Sbjct: 217 GISIGKLDLYVAAGGFHPRRVLPVVLDIGTNNQKLLNDPNYLGL 260
>UniRef50_A1ZAF7 Cluster: Malic enzyme; n=5; Sophophora|Rep: Malic
enzyme - Drosophila melanogaster (Fruit fly)
Length = 603
Score = 102 bits (245), Expect = 6e-21
Identities = 44/84 (52%), Positives = 62/84 (73%)
Frame = +1
Query: 256 FVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAI 435
F+ +N+ + +PIVYTPTVG +GL +++ LFI+IHDKGH+ D++ NW + V+AI
Sbjct: 112 FIKENIEKSLPIVYTPTVGDVVATYGLNFQQAISLFISIHDKGHIRDLMHNWVDEGVKAI 171
Query: 436 VVTDGERILGLGDLGACGMGIPVG 507
VTDG R+LGLGD+GA MGI +G
Sbjct: 172 CVTDGGRVLGLGDMGANAMGISLG 195
Score = 55.2 bits (127), Expect = 1e-06
Identities = 23/49 (46%), Positives = 33/49 (67%)
Frame = +3
Query: 474 LGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 620
+G G G++ LYTALG I P +P+ +DVGT+ Q++L DPLY+G
Sbjct: 185 MGANAMGISLGKMILYTALGSIPPSTLMPVCLDVGTDNQALLQDPLYVG 233
Score = 33.5 bits (73), Expect = 4.2
Identities = 15/61 (24%), Positives = 30/61 (49%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F + LGI GL+P V++ ++Q+ + + + ++ YL + R+ L+
Sbjct: 50 GLAFTIKERQRLGIMGLMPCSVRSMDDQMNAALANFEARPTDIARFTYLSAVHHRHRRLY 109
Query: 251 Y 253
Y
Sbjct: 110 Y 110
>UniRef50_P78715 Cluster: Malic enzyme, hydrogenosomal precursor;
n=1; Neocallimastix frontalis|Rep: Malic enzyme,
hydrogenosomal precursor - Neocallimastix frontalis
(Rumen fungus)
Length = 592
Score = 102 bits (245), Expect = 6e-21
Identities = 45/83 (54%), Positives = 58/83 (69%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
+ +N E+ PI+YTP VG ACQKF ++ + RG++ + D+G + V NWP DV IV
Sbjct: 122 ILENFVELAPIIYTPVVGEACQKFHKIFTQTRGMYFSTADRGQMSAVAANWPYDDVDVIV 181
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTDG RILGLGDLGA GM IP+G
Sbjct: 182 VTDGSRILGLGDLGAGGMQIPIG 204
Score = 58.0 bits (134), Expect = 2e-07
Identities = 25/50 (50%), Positives = 36/50 (72%)
Frame = +2
Query: 104 LGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFY 253
LGI GL+PPR ++ E Q + CK ++D+ +PL K+IYL L +RNE L+Y
Sbjct: 70 LGIRGLVPPRPQSLEAQYKRCKTNLDKISDPLEKFIYLNHLQNRNETLYY 119
Score = 57.2 bits (132), Expect = 3e-07
Identities = 23/42 (54%), Positives = 30/42 (71%)
Frame = +3
Query: 498 PCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
P G+L LY GGI P LPI +DVGTN + +L+DPLY+G+
Sbjct: 202 PIGKLTLYVCGGGINPRNVLPIVLDVGTNNKELLNDPLYLGM 243
Score = 32.7 bits (71), Expect = 7.3
Identities = 15/29 (51%), Positives = 18/29 (62%)
Frame = +3
Query: 33 SGLDHLKHPGLNKGMAFTIEERQSWGSTG 119
+GLD L P LNKG AFT +E+ G G
Sbjct: 46 TGLDILNDPKLNKGSAFTADEKDRLGIRG 74
>UniRef50_Q016K2 Cluster: NADP dependent malic enzyme; n=2;
Ostreococcus|Rep: NADP dependent malic enzyme -
Ostreococcus tauri
Length = 641
Score = 101 bits (242), Expect = 1e-20
Identities = 41/85 (48%), Positives = 64/85 (75%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
V D++ E++P++ PTV C++ GL+YR+PRGL++++ DKG VY +LKNWP +V+A+V
Sbjct: 158 VKDHLEELLPVLAEPTVWQVCREAGLMYRQPRGLYVSMQDKGSVYRLLKNWPVRNVKAVV 217
Query: 439 VTDGERILGLGDLGACGMGIPVGNS 513
+TDG+R+ G+GDLG GM V +
Sbjct: 218 LTDGQRVTGIGDLGVQGMPAAVSKA 242
Score = 51.6 bits (118), Expect = 1e-05
Identities = 22/37 (59%), Positives = 29/37 (78%)
Frame = +3
Query: 513 ALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
+L+TALGG+ P LPI IDVGT+ Q++L+D YIGL
Sbjct: 243 SLFTALGGLDPADVLPICIDVGTDNQTLLEDKFYIGL 279
Score = 41.9 bits (94), Expect = 0.012
Identities = 23/61 (37%), Positives = 30/61 (49%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F L + GLLPP V Q QVE + R + + K+ +L L +RNE LF
Sbjct: 95 GMSFARDERDRLNLRGLLPPAVFDQATQVERVIERLRRVTSGVEKHAWLPALYERNERLF 154
Query: 251 Y 253
Y
Sbjct: 155 Y 155
>UniRef50_Q4PC56 Cluster: Malic enzyme; n=1; Ustilago maydis|Rep:
Malic enzyme - Ustilago maydis (Smut fungus)
Length = 634
Score = 100 bits (240), Expect = 2e-20
Identities = 45/82 (54%), Positives = 58/82 (70%), Gaps = 2/82 (2%)
Frame = +1
Query: 268 NVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNW--PETDVRAIVV 441
N E++P++YTPTVG ACQKF +YRRP GL I++ DKG + +++NW P R V+
Sbjct: 155 NKEEILPLIYTPTVGEACQKFSHIYRRPEGLSISLEDKGKIASIVENWPVPAGSPRIAVI 214
Query: 442 TDGERILGLGDLGACGMGIPVG 507
TDG RILGLGDLG G GI +G
Sbjct: 215 TDGSRILGLGDLGWNGQGISIG 236
Score = 54.0 bits (124), Expect = 3e-06
Identities = 25/50 (50%), Positives = 32/50 (64%)
Frame = +3
Query: 474 LGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
LG G G+L+LY A GI P LPI +D+GTN + L+DPLY+GL
Sbjct: 226 LGWNGQGISIGKLSLYVAGAGIHPRATLPIVVDLGTNNKKNLEDPLYLGL 275
Score = 38.3 bits (85), Expect = 0.15
Identities = 19/59 (32%), Positives = 28/59 (47%)
Frame = +2
Query: 77 GFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFY 253
GF + + LG+ GLLPP ++ QV + PL K++ L L N L+Y
Sbjct: 91 GFSYEKRDQLGLRGLLPPAKQSLNTQVLRVLHQLRSKSTPLEKHVMLASLRQTNTRLYY 149
>UniRef50_Q9HE50 Cluster: Malic enzyme; n=6; Pezizomycotina|Rep:
Malic enzyme - Neurospora crassa
Length = 1023
Score = 97.5 bits (232), Expect = 2e-19
Identities = 41/81 (50%), Positives = 55/81 (67%)
Frame = +1
Query: 265 DNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVT 444
D+ EMMP+VYTPT+G C ++ +Y RP L+I+I + + +L+NWP VVT
Sbjct: 549 DHAKEMMPLVYTPTIGDVCLQYSTLYTRPEALYISIKQRKSIRTILRNWPYPQPEICVVT 608
Query: 445 DGERILGLGDLGACGMGIPVG 507
DG RILGLGDLG G+GIP+G
Sbjct: 609 DGSRILGLGDLGVNGVGIPIG 629
Score = 56.0 bits (129), Expect = 7e-07
Identities = 25/44 (56%), Positives = 31/44 (70%)
Frame = +3
Query: 492 GHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
G P G+LALYTA GI P + LPI +D GT ++ L DPLY+GL
Sbjct: 625 GIPIGKLALYTAAAGIHPDKTLPIVLDCGTANETNLKDPLYLGL 668
Score = 33.1 bits (72), Expect = 5.6
Identities = 17/61 (27%), Positives = 29/61 (47%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F + GL+P ++ E+QVE I + +++Y+YL + +N LF
Sbjct: 484 GTSFTPEERVAKNLTGLIPHVMEDSEKQVERALKMIRTRQTDIDRYLYLSTIKSQNVDLF 543
Query: 251 Y 253
Y
Sbjct: 544 Y 544
>UniRef50_Q875H8 Cluster: Malic enzyme; n=1; Mucor
circinelloides|Rep: Malic enzyme - Mucor circinelloides
Length = 617
Score = 95.5 bits (227), Expect = 9e-19
Identities = 42/83 (50%), Positives = 58/83 (69%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
+ +++ E+ I+YTPTVGLA Q +YRR RG++ + D+G + ++ NWP V IV
Sbjct: 125 IMEHLEELAGIIYTPTVGLASQMSHSIYRRSRGMYFSSQDRGQMSAMVYNWPHDKVDVIV 184
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTDG R+LGLGDLGA GM IP+G
Sbjct: 185 VTDGSRVLGLGDLGANGMEIPIG 207
Score = 62.1 bits (144), Expect = 1e-08
Identities = 24/42 (57%), Positives = 33/42 (78%)
Frame = +3
Query: 498 PCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
P G+L+LY A GGI+P LP+ +DVGTN Q +L+DPLY+G+
Sbjct: 205 PIGKLSLYVAAGGIRPRAVLPVVLDVGTNNQDLLNDPLYLGM 246
Score = 50.4 bits (115), Expect = 3e-05
Identities = 22/50 (44%), Positives = 33/50 (66%)
Frame = +2
Query: 104 LGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFY 253
L I GL+PPR + ++Q+ K ++D E PL K+++L L DRNE L+Y
Sbjct: 73 LSIRGLVPPRCQEMDKQLLRIKRNLDACETPLAKFVFLAALHDRNETLYY 122
>UniRef50_Q00XN9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus tauri
Length = 639
Score = 93.5 bits (222), Expect = 4e-18
Identities = 43/83 (51%), Positives = 57/83 (68%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
V D++ E+ PI+YTPTVG AC F + RR RG++ ++ D+G + ++ NW + V IV
Sbjct: 156 VHDHIEELAPIIYTPTVGDACLNFSKLLRRARGMYFSVDDRGDINSMMFNW-KRSVSVIV 214
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTDG RILGLGDLG GMGI G
Sbjct: 215 VTDGSRILGLGDLGTNGMGISQG 237
Score = 50.4 bits (115), Expect = 3e-05
Identities = 22/50 (44%), Positives = 31/50 (62%)
Frame = +3
Query: 474 LGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
LG G G++ LY A GG P LP+ +DVGTN + +L+DP Y+G+
Sbjct: 227 LGTNGMGISQGKVDLYVAGGGFDPQHVLPVVLDVGTNNEDLLNDPYYLGV 276
Score = 41.5 bits (93), Expect = 0.016
Identities = 23/61 (37%), Positives = 29/61 (47%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F LG+ GL+PPR +Q E PL+K+ +L L DRNE LF
Sbjct: 93 GTSFTASERERLGVRGLVPPRFFPIGQQATKIWAQNQSLERPLDKWQHLQDLKDRNETLF 152
Query: 251 Y 253
Y
Sbjct: 153 Y 153
>UniRef50_Q4QAQ6 Cluster: Malic enzyme, putative; n=20;
Trypanosomatidae|Rep: Malic enzyme, putative -
Leishmania major
Length = 573
Score = 92.3 bits (219), Expect = 9e-18
Identities = 39/77 (50%), Positives = 59/77 (76%)
Frame = +1
Query: 277 EMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGER 456
+ +PIVYTPTVG ACQ++G +Y++ GL++ + KG V +++N +T++ IV+TDG R
Sbjct: 100 QTLPIVYTPTVGEACQRYGDLYQKDHGLYLDVASKGKVRRLIQNLRKTNIDVIVITDGSR 159
Query: 457 ILGLGDLGACGMGIPVG 507
ILGLGDLG+ G+GI +G
Sbjct: 160 ILGLGDLGSNGIGISIG 176
Score = 53.2 bits (122), Expect = 5e-06
Identities = 23/50 (46%), Positives = 33/50 (66%)
Frame = +3
Query: 474 LGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
LG G G+ +LY A GG+KP + LP+ +DVGTN + ++PLY+GL
Sbjct: 166 LGSNGIGISIGKCSLYVAAGGVKPSRVLPVVMDVGTNNLELRNNPLYLGL 215
Score = 44.8 bits (101), Expect = 0.002
Identities = 21/61 (34%), Positives = 34/61 (55%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F S + + GLLPP V+T ++QVE ++R+ P+N+Y L + + N L+
Sbjct: 31 GTAFTAAERSHMNVEGLLPPSVETLDDQVERYWDQLNRFNEPINRYQLLRNVQNTNVTLY 90
Query: 251 Y 253
Y
Sbjct: 91 Y 91
>UniRef50_Q5K758 Cluster: Malic enzyme; n=1; Filobasidiella
neoformans|Rep: Malic enzyme - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 600
Score = 91.5 bits (217), Expect = 1e-17
Identities = 44/84 (52%), Positives = 56/84 (66%), Gaps = 3/84 (3%)
Frame = +1
Query: 265 DNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDV---RAI 435
D + E+ PIVYTPTVG ACQK+ +Y P GL++ I DK + ++L + V + +
Sbjct: 128 DELTELAPIVYTPTVGEACQKYSQIYSGPEGLYLNIEDKDRIPEILHQYASKLVAPPQIL 187
Query: 436 VVTDGERILGLGDLGACGMGIPVG 507
VVTDG RILGLGDLG GMGI VG
Sbjct: 188 VVTDGSRILGLGDLGIGGMGISVG 211
Score = 60.1 bits (139), Expect = 4e-08
Identities = 24/44 (54%), Positives = 33/44 (75%)
Frame = +3
Query: 492 GHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
G G+L LY A GG+ PH CLP+ +D+GTN +++ +DPLYIGL
Sbjct: 207 GISVGKLNLYVAGGGVNPHGCLPVVLDMGTNNEAVRNDPLYIGL 250
>UniRef50_A4RQC9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus lucimarinus CCE9901
Length = 549
Score = 89.8 bits (213), Expect = 5e-17
Identities = 41/83 (49%), Positives = 55/83 (66%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
+ +++ ++MPIVYTPTVG AC F +YR G++ + D G + +L NWP + IV
Sbjct: 84 LVEHLEDLMPIVYTPTVGEACINFDALYRNRCGMYFSRLDSGVMRRMLDNWPSPETEIIV 143
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTDG R+LGLGDLG GM I VG
Sbjct: 144 VTDGGRVLGLGDLGTNGMAISVG 166
Score = 48.0 bits (109), Expect = 2e-04
Identities = 24/61 (39%), Positives = 35/61 (57%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G GF + LG+ GLLP + +T E QV+ + +E +N+YI+L L +NE LF
Sbjct: 21 GTGFTFTQRERLGLRGLLPRKYETVEIQVKRAWTQLCAFEEDMNRYIFLENLHMQNERLF 80
Query: 251 Y 253
Y
Sbjct: 81 Y 81
Score = 36.3 bits (80), Expect = 0.60
Identities = 13/39 (33%), Positives = 25/39 (64%)
Frame = +3
Query: 504 GQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 620
G+++LY A GG P + +P+ +D+GT+ ++ Y+G
Sbjct: 166 GKVSLYVASGGFDPAKSMPVCLDLGTSNVALRAHDFYLG 204
>UniRef50_A0Q531 Cluster: NAD-dependent malic enzyme; n=10;
Francisella tularensis|Rep: NAD-dependent malic enzyme -
Francisella tularensis subsp. novicida (strain U112)
Length = 604
Score = 89.4 bits (212), Expect = 6e-17
Identities = 39/84 (46%), Positives = 57/84 (67%)
Frame = +1
Query: 256 FVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAI 435
FV +N+ E+MPI+YTPTVG A QK+ +R+ GLFI+I K H+ +L+ + + +
Sbjct: 101 FVRENLEEIMPIIYTPTVGEAVQKYSSSFRKQSGLFISISHKKHIARILERYEYNSIDLV 160
Query: 436 VVTDGERILGLGDLGACGMGIPVG 507
+VTDGE +LG+GD G GM I +G
Sbjct: 161 LVTDGEAVLGIGDQGIGGMNISIG 184
Score = 43.2 bits (97), Expect = 0.005
Identities = 16/40 (40%), Positives = 28/40 (70%)
Frame = +3
Query: 504 GQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
G++ +Y A GI P + LP+ +D+GTN ++L+ P Y+G+
Sbjct: 184 GKIMVYVAASGIDPARVLPVQLDMGTNNDALLNAPGYLGV 223
Score = 38.3 bits (85), Expect = 0.15
Identities = 19/46 (41%), Positives = 26/46 (56%)
Frame = +2
Query: 116 GLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFY 253
G LP +V++ EEQ + +D N L KY++L L D N LFY
Sbjct: 54 GYLPEKVESLEEQAIRVRRQLDLKPNSLEKYVFLNRLHDLNTTLFY 99
>UniRef50_A1SVL3 Cluster: Malic enzyme aka malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=4;
Gammaproteobacteria|Rep: Malic enzyme aka malate
dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)) -
Psychromonas ingrahamii (strain 37)
Length = 571
Score = 84.6 bits (200), Expect = 2e-15
Identities = 38/83 (45%), Positives = 56/83 (67%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
++ N+ EM PI+YTPTVG ACQ+F ++ RGL++T + V + + + D++ IV
Sbjct: 99 ISRNIEEMTPIIYTPTVGKACQEFSHRFQIARGLYLTTDNIHDVGSMAREFTGKDIQIIV 158
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTD + ILG+GD G GMGIP+G
Sbjct: 159 VTDSQGILGIGDQGVGGMGIPIG 181
Score = 57.6 bits (133), Expect = 2e-07
Identities = 22/44 (50%), Positives = 32/44 (72%)
Frame = +3
Query: 492 GHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
G P G+L+LYT GI P C+PI +D+GT+ Q +L DP+Y+G+
Sbjct: 177 GIPIGKLSLYTLGAGIHPDHCMPIALDIGTDNQDLLADPMYLGI 220
Score = 47.6 bits (108), Expect = 2e-04
Identities = 23/58 (39%), Positives = 32/58 (55%)
Frame = +2
Query: 80 FYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFY 253
F ++ ++GLLPPRV+T E+Q++ + KY YL L DRNE LFY
Sbjct: 39 FTYQEREDFDLNGLLPPRVQTFEDQLKRVYQGFSASSTDIEKYQYLRALQDRNETLFY 96
>UniRef50_A6XP71 Cluster: Malic enzyme protein 2; n=2;
Mucoromycotina|Rep: Malic enzyme protein 2 - Mortierella
alpina (Mortierella renispora)
Length = 669
Score = 83.8 bits (198), Expect = 3e-15
Identities = 42/95 (44%), Positives = 60/95 (63%), Gaps = 12/95 (12%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYR------RPRGLFITIHDKGHVYDVLKNW--- 411
V D + E +P++YTPTVG ACQ + +Y +P GLF++I+D ++ +++N+
Sbjct: 172 VGDQLEETLPLIYTPTVGTACQNYSSIYPFLAPPGQPDGLFLSINDLPNLTQIIQNYKPF 231
Query: 412 ---PETDVRAIVVTDGERILGLGDLGACGMGIPVG 507
P + V+TDG RILGLGDLG GMGIPVG
Sbjct: 232 PQDPSLTPQIAVITDGSRILGLGDLGVGGMGIPVG 266
Score = 52.4 bits (120), Expect = 8e-06
Identities = 23/44 (52%), Positives = 29/44 (65%)
Frame = +3
Query: 492 GHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
G P G+L LY A GI P + LPIT+D+GTN + L D Y+GL
Sbjct: 262 GIPVGKLQLYVAGAGIDPRRTLPITLDLGTNNEDKLKDEFYLGL 305
Score = 32.3 bits (70), Expect = 9.7
Identities = 16/52 (30%), Positives = 27/52 (51%)
Frame = +2
Query: 98 SVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFY 253
S L + GL P +V++ E Q + + + + KY++L L + N LFY
Sbjct: 118 SALHLQGLTPAKVESFELQKKRALAQLRSKSSDIEKYVFLAWLRNTNVRLFY 169
>UniRef50_A4SKB8 Cluster: NAD-dependent malic enzyme; n=2;
Aeromonas|Rep: NAD-dependent malic enzyme - Aeromonas
salmonicida (strain A449)
Length = 516
Score = 83.0 bits (196), Expect = 5e-15
Identities = 39/83 (46%), Positives = 57/83 (68%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
V ++ E++PI+YTP VG ACQ+ +Y R GL+++ HD+ + D + E +V IV
Sbjct: 70 VRHHLPELLPIIYTPVVGEACQRHSDLYLRSHGLYLSWHDRDDL-DAIFAAVEQEVDVIV 128
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
++DGER+LGLGDLG GMGI +G
Sbjct: 129 ISDGERVLGLGDLGIGGMGICIG 151
Score = 51.6 bits (118), Expect = 1e-05
Identities = 21/39 (53%), Positives = 29/39 (74%)
Frame = +3
Query: 504 GQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 620
G+LALY+A GGI P + LP+ +DVGTN +L+D Y+G
Sbjct: 151 GKLALYSAAGGINPARTLPLCVDVGTNNPELLEDDSYLG 189
>UniRef50_Q9RYN4 Cluster: Malate oxidoreductase; n=6;
Deinococci|Rep: Malate oxidoreductase - Deinococcus
radiodurans
Length = 580
Score = 82.2 bits (194), Expect = 9e-15
Identities = 41/83 (49%), Positives = 51/83 (61%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
++ +V EM+PIVYTPTVG A +KF +YR PRGL ++ L N P DVR IV
Sbjct: 112 LSHHVEEMLPIVYTPTVGDAVKKFSQIYRYPRGLTLSTRTIERAEQALANVPLNDVRIIV 171
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
TD ILG+GD G GM I +G
Sbjct: 172 ATDSSAILGIGDQGFGGMAISIG 194
Score = 47.6 bits (108), Expect = 2e-04
Identities = 18/40 (45%), Positives = 28/40 (70%)
Frame = +3
Query: 504 GQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
G+L+LYT GG+ P + LP+ +DVGT + +DP Y+G+
Sbjct: 194 GKLSLYTVAGGVGPDKTLPVELDVGTGRADLREDPHYLGV 233
Score = 41.1 bits (92), Expect = 0.021
Identities = 22/61 (36%), Positives = 29/61 (47%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F G+ GLL P+V + E +E + L K++YL L DRNE LF
Sbjct: 49 GTAFTAEEREAHGLDGLLAPQVDSLEVLIERAYREFSKRGAALEKHVYLRNLQDRNEVLF 108
Query: 251 Y 253
Y
Sbjct: 109 Y 109
>UniRef50_Q5CS07 Cluster: Malic enzyme; n=2; Cryptosporidium|Rep:
Malic enzyme - Cryptosporidium parvum Iowa II
Length = 614
Score = 79.0 bits (186), Expect = 9e-14
Identities = 39/81 (48%), Positives = 53/81 (65%), Gaps = 4/81 (4%)
Frame = +1
Query: 277 EMMPIVYTPTVGLACQKFGL--VYRR--PRGLFITIHDKGHVYDVLKNWPETDVRAIVVT 444
++ P+VYTPTVG C +F R GL++ KG +Y++LK++ D+ IV+T
Sbjct: 147 DLTPLVYTPTVGEGCIEFSRNPTIRNWLGSGLYLNKSHKGRIYEILKDFKSDDIEIIVLT 206
Query: 445 DGERILGLGDLGACGMGIPVG 507
DG RILGLGDLG GMGIP+G
Sbjct: 207 DGGRILGLGDLGLNGMGIPMG 227
Score = 57.2 bits (132), Expect = 3e-07
Identities = 25/50 (50%), Positives = 34/50 (68%)
Frame = +3
Query: 474 LGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
LG G P G+L+LY LGGI P + LPI++D+GTNT +L D Y+G+
Sbjct: 217 LGLNGMGIPMGKLSLYITLGGIDPSKVLPISLDIGTNTNDILSDKYYLGI 266
Score = 36.3 bits (80), Expect = 0.60
Identities = 14/30 (46%), Positives = 23/30 (76%)
Frame = +3
Query: 30 LSGLDHLKHPGLNKGMAFTIEERQSWGSTG 119
L G++ L++P NKG++FT+EER+ +G G
Sbjct: 64 LKGIELLRNPFYNKGLSFTMEERKEYGLEG 93
Score = 34.7 bits (76), Expect = 1.8
Identities = 17/61 (27%), Positives = 31/61 (50%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F G+ GLLP + +T +EQV +I++ ++ + KY +L + + LF
Sbjct: 78 GLSFTMEERKEYGLEGLLPAKYETIDEQVSRLWTAINKIDSNIGKYTFLENIRSSSFILF 137
Query: 251 Y 253
+
Sbjct: 138 H 138
>UniRef50_Q95061 Cluster: Malic enzyme; n=2; Giardia
intestinalis|Rep: Malic enzyme - Giardia lamblia
(Giardia intestinalis)
Length = 557
Score = 76.6 bits (180), Expect = 5e-13
Identities = 40/85 (47%), Positives = 51/85 (60%), Gaps = 1/85 (1%)
Frame = +1
Query: 256 FVADNVAEMMPIVYTPTVGLACQKFGLVYRR-PRGLFITIHDKGHVYDVLKNWPETDVRA 432
F + E++PIVYTPTVG AC + L+++ PRG ++ G V + WP + R
Sbjct: 79 FCLKYLKEVLPIVYTPTVGTACSNYSLLWQGYPRGFYLNRTHLGKVKQIFDQWPYSP-RI 137
Query: 433 IVVTDGERILGLGDLGACGMGIPVG 507
IV TDG RILGLGDLG G I VG
Sbjct: 138 IVATDGTRILGLGDLGTGGHQICVG 162
Score = 44.4 bits (100), Expect = 0.002
Identities = 18/40 (45%), Positives = 25/40 (62%)
Frame = +3
Query: 504 GQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
G+L LY+ GG P LPI+ D G NT + +DP Y+G+
Sbjct: 162 GKLTLYSLGGGFAPEHTLPISFDFGCNTDKIREDPHYLGI 201
Score = 39.9 bits (89), Expect = 0.048
Identities = 18/43 (41%), Positives = 25/43 (58%)
Frame = +2
Query: 122 LPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
LP RV+T E+Q+ C+ D P K++YL L + NE LF
Sbjct: 34 LPARVETIEQQISRCRAQFDVLTTPTEKWLYLTRLQEVNETLF 76
>UniRef50_Q7SHJ8 Cluster: Malic enzyme; n=12; Pezizomycotina|Rep:
Malic enzyme - Neurospora crassa
Length = 611
Score = 74.9 bits (176), Expect = 1e-12
Identities = 39/82 (47%), Positives = 52/82 (63%), Gaps = 2/82 (2%)
Frame = +1
Query: 265 DNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNW--PETDVRAIV 438
D++ EM +VYTPT G A Q + ++RRP G+F+ I+D V L W PE D+ IV
Sbjct: 112 DHLDEMFSVVYTPTEGEAIQNYSRLFRRPEGVFLNINDMDSVKRDLAQWGKPE-DIDYIV 170
Query: 439 VTDGERILGLGDLGACGMGIPV 504
VTDGE ILG+GD G G+ I +
Sbjct: 171 VTDGEEILGIGDQGCGGILISI 192
Score = 47.2 bits (107), Expect = 3e-04
Identities = 19/39 (48%), Positives = 27/39 (69%)
Frame = +3
Query: 507 QLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
+L L T GGI P++ LP+ +D GTN + +L D LY+GL
Sbjct: 194 KLVLMTICGGIHPNRVLPVVLDCGTNNEELLKDDLYLGL 232
Score = 39.9 bits (89), Expect = 0.048
Identities = 19/61 (31%), Positives = 31/61 (50%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F +HGLLPP++++ E+QV+ N L K ++ + ++NE LF
Sbjct: 47 GSAFTKEERRDFALHGLLPPQIQSLEQQVQRAYEQYCSQPNDLAKNTFMTSMKEQNEVLF 106
Query: 251 Y 253
Y
Sbjct: 107 Y 107
>UniRef50_P45868 Cluster: Probable NAD-dependent malic enzyme 2;
n=37; Bacteria|Rep: Probable NAD-dependent malic enzyme
2 - Bacillus subtilis
Length = 582
Score = 74.5 bits (175), Expect = 2e-12
Identities = 47/134 (35%), Positives = 75/134 (55%), Gaps = 2/134 (1%)
Frame = +1
Query: 112 PRVVTTTSQDARGAG*TMQALDRQIRKST*QVHLSYGALGPQ*ASVLPFVADNVAEMMPI 291
P V + Q A+ A QA ++R++ V+LS A + + +++ EM+P+
Sbjct: 65 PPTVLSLDQQAQRAYEQFQAQPDRLRQN---VYLSDLANRNE-VLFYKLLKNHLREMLPV 120
Query: 292 VYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPET--DVRAIVVTDGERILG 465
VYTPTVG A Q++ YRRP+G++++I + + +N T D+ IV TD E ILG
Sbjct: 121 VYTPTVGEAIQEYSHEYRRPQGIYLSIDNIDGIEKAFENLHATAGDIDLIVATDSESILG 180
Query: 466 LGDLGACGMGIPVG 507
+GD G G+ I +G
Sbjct: 181 IGDWGVGGINIAIG 194
Score = 58.0 bits (134), Expect = 2e-07
Identities = 25/53 (47%), Positives = 36/53 (67%)
Frame = +3
Query: 462 GSWRLGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 620
G W +G + G+LA+YTA GI P + +P+ +DVGTN + +L+DPLYIG
Sbjct: 182 GDWGVGGINIA--IGKLAVYTAAAGIDPSRVIPVVLDVGTNNEKLLNDPLYIG 232
Score = 41.1 bits (92), Expect = 0.021
Identities = 21/61 (34%), Positives = 30/61 (49%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F LG+ GLLPP V + ++Q + + L + +YL L +RNE LF
Sbjct: 47 GVAFSLEERQELGLEGLLPPTVLSLDQQAQRAYEQFQAQPDRLRQNVYLSDLANRNEVLF 106
Query: 251 Y 253
Y
Sbjct: 107 Y 107
Score = 35.1 bits (77), Expect = 1.4
Identities = 17/37 (45%), Positives = 23/37 (62%)
Frame = +3
Query: 9 DGQPTSGLSGLDHLKHPGLNKGMAFTIEERQSWGSTG 119
+G + L G + L P LNKG+AF++EERQ G G
Sbjct: 26 EGHLETTLRGKEVLSIPTLNKGVAFSLEERQELGLEG 62
>UniRef50_A3YYQ0 Cluster: Malate oxidoreductase; n=1; Synechococcus
sp. WH 5701|Rep: Malate oxidoreductase - Synechococcus
sp. WH 5701
Length = 517
Score = 73.3 bits (172), Expect = 4e-12
Identities = 38/85 (44%), Positives = 52/85 (61%), Gaps = 1/85 (1%)
Frame = +1
Query: 256 FVADNVAEMMPIVYTPTVGLACQKFGLVYRRPR-GLFITIHDKGHVYDVLKNWPETDVRA 432
F+AD++ +MPIVYTPTVG A Q+F L YR P G+F+ D + VL V
Sbjct: 42 FLADHIEAVMPIVYTPTVGAAIQRFSLDYRTPSGGVFLAAPDLERIESVLSQAATGPVDL 101
Query: 433 IVVTDGERILGLGDLGACGMGIPVG 507
I++TD + ILG+GD G G+ I +G
Sbjct: 102 ILITDSQGILGIGDQGIGGIEICLG 126
Score = 45.2 bits (102), Expect = 0.001
Identities = 18/39 (46%), Positives = 28/39 (71%)
Frame = +3
Query: 504 GQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 620
G+LA+YT G+ P + LP+ +DVGT+ +L++PLY G
Sbjct: 126 GKLAVYTLCAGLDPARVLPLVLDVGTDRVELLENPLYPG 164
>UniRef50_Q6AL43 Cluster: Related to NAD-dependent malic enzyme;
n=1; Desulfotalea psychrophila|Rep: Related to
NAD-dependent malic enzyme - Desulfotalea psychrophila
Length = 578
Score = 72.1 bits (169), Expect = 1e-11
Identities = 33/83 (39%), Positives = 51/83 (61%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
+ ++ + M I+YTPTVGLA QK+ ++R+ GL + D+L+ + D+R V
Sbjct: 100 IQSDLEKFMGIIYTPTVGLAVQKYSAMFRQANGLHFSPDTIDQAEDILRRFAHRDIRVAV 159
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTD + ILG+GD GA G+ I +G
Sbjct: 160 VTDNQGILGIGDQGAGGIAICLG 182
Score = 47.2 bits (107), Expect = 3e-04
Identities = 19/39 (48%), Positives = 28/39 (71%)
Frame = +3
Query: 504 GQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 620
G+L LYT GI P CLPI++D+GT+ +++L D Y+G
Sbjct: 182 GKLMLYTQGAGIAPWHCLPISLDIGTDNEALLADKHYLG 220
Score = 41.9 bits (94), Expect = 0.012
Identities = 19/53 (35%), Positives = 27/53 (50%)
Frame = +2
Query: 80 FYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRN 238
F + G+ G LPP + E QVE C + + E+ KYI++ L DRN
Sbjct: 40 FSSKERDDFGLQGSLPPGFRDLEAQVENCHIKLGEKESEEEKYIFIRSLFDRN 92
>UniRef50_A2QY66 Cluster: Malic enzyme; n=2; cellular organisms|Rep:
Malic enzyme - Aspergillus niger
Length = 609
Score = 67.7 bits (158), Expect = 2e-10
Identities = 33/80 (41%), Positives = 50/80 (62%), Gaps = 1/80 (1%)
Frame = +1
Query: 268 NVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPE-TDVRAIVVT 444
++ EM+ I+YTPT G A Q + ++R+P G F+ I D+ + + L N+ +V IVV+
Sbjct: 135 HLKEMLSIIYTPTEGDAIQNYSRLFRKPEGCFLNIRDQDRIEECLSNFSRGEEVDYIVVS 194
Query: 445 DGERILGLGDLGACGMGIPV 504
DGE ILG+GD G + I V
Sbjct: 195 DGEEILGIGDQGVGAILISV 214
Score = 44.0 bits (99), Expect = 0.003
Identities = 19/39 (48%), Positives = 27/39 (69%)
Frame = +3
Query: 507 QLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
+LAL T GI P + LP+ +D GT+ +S+L D LY+GL
Sbjct: 216 KLALTTLCAGIHPSRQLPVVLDCGTDNESLLTDELYLGL 254
Score = 42.7 bits (96), Expect = 0.007
Identities = 20/61 (32%), Positives = 30/61 (49%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F +HGLLPP ++T EEQV+ +N L K ++ + +NE L+
Sbjct: 69 GSAFTEEERKTFKLHGLLPPNIQTLEEQVQRAYEQYSSRDNDLAKNTFMASMKAQNEVLY 128
Query: 251 Y 253
Y
Sbjct: 129 Y 129
>UniRef50_P40375 Cluster: NAD-dependent malic enzyme; n=3;
Schizosaccharomyces pombe|Rep: NAD-dependent malic
enzyme - Schizosaccharomyces pombe (Fission yeast)
Length = 565
Score = 65.3 bits (152), Expect = 1e-09
Identities = 33/85 (38%), Positives = 54/85 (63%), Gaps = 3/85 (3%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITI--HDKGHVYDVLKNWPETD-VR 429
++ ++ EM+PI+YTPT G A ++F +YR P G ++ I +D ++ L + ++D V
Sbjct: 91 ISQHLIEMIPIIYTPTEGDAIKQFSDIYRYPEGCYLDIDHNDLSYIKQQLSEFGKSDSVE 150
Query: 430 AIVVTDGERILGLGDLGACGMGIPV 504
I++TD E ILG+GD G G+ I V
Sbjct: 151 YIIITDSEGILGIGDQGVGGVLISV 175
Score = 35.1 bits (77), Expect = 1.4
Identities = 15/36 (41%), Positives = 23/36 (63%)
Frame = +3
Query: 516 LYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
L T G+ P++ LPI +DVGTN ++ + Y+GL
Sbjct: 180 LMTLCAGLDPNRFLPIVLDVGTNNETHRKNHQYMGL 215
Score = 33.9 bits (74), Expect = 3.2
Identities = 21/52 (40%), Positives = 29/52 (55%), Gaps = 4/52 (7%)
Frame = +2
Query: 110 IHGLLPPRVKTQEEQVELCKLSIDRY----ENPLNKYIYLMGLLDRNEHLFY 253
I LPP V+T ++QV+ C D+Y + PL K +YL L N+ LFY
Sbjct: 40 ISSRLPPIVETLQQQVDRC---YDQYKAIGDEPLQKNLYLSQLSVTNQTLFY 88
>UniRef50_Q5KBK5 Cluster: Nad-dependent malic enzyme, putative; n=2;
Filobasidiella neoformans|Rep: Nad-dependent malic
enzyme, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 584
Score = 61.3 bits (142), Expect = 2e-08
Identities = 33/78 (42%), Positives = 47/78 (60%), Gaps = 1/78 (1%)
Frame = +1
Query: 268 NVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFIT-IHDKGHVYDVLKNWPETDVRAIVVT 444
++ EM PIVYTPT A + ++RR GL++T +K D L ++ IVV+
Sbjct: 106 HLVEMFPIVYTPTEADAIADYSHLFRRSEGLYLTPPGEKNMEEDFLDACEGRELELIVVS 165
Query: 445 DGERILGLGDLGACGMGI 498
DGE ILG+GD G+ G+GI
Sbjct: 166 DGEAILGIGDQGSGGIGI 183
Score = 52.8 bits (121), Expect = 6e-06
Identities = 20/35 (57%), Positives = 28/35 (80%)
Frame = +3
Query: 516 LYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 620
+Y+ + G+ P +CL IT+DVGTN Q +L+DPLYIG
Sbjct: 190 IYSLIAGVDPAKCLAITLDVGTNNQDLLNDPLYIG 224
>UniRef50_Q48796 Cluster: Malolactic enzyme; n=49; Bacteria|Rep:
Malolactic enzyme - Oenococcus oeni (Leuconostoc oenos)
Length = 541
Score = 60.5 bits (140), Expect = 3e-08
Identities = 31/84 (36%), Positives = 49/84 (58%), Gaps = 2/84 (2%)
Frame = +1
Query: 262 ADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGL-FITIHDKGHVYDVLKNWPE-TDVRAI 435
+ +V E MPIVY PT+ + + ++ P+G F+ I+ ++ LKN D++ +
Sbjct: 80 SQHVVEFMPIVYDPTIADTIENYSELFVEPQGAAFLDINHPENIQSTLKNAANGRDIKLL 139
Query: 436 VVTDGERILGLGDLGACGMGIPVG 507
VV+D E ILG+GD G G+ I VG
Sbjct: 140 VVSDAEGILGIGDWGVQGVDIAVG 163
Score = 46.4 bits (105), Expect = 6e-04
Identities = 18/39 (46%), Positives = 25/39 (64%)
Frame = +3
Query: 504 GQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 620
G+L +YT GI P L + ID GTN + +L DP+Y+G
Sbjct: 163 GKLMVYTVAAGIDPSTVLAVVIDAGTNNEKLLKDPMYLG 201
Score = 39.9 bits (89), Expect = 0.048
Identities = 20/61 (32%), Positives = 31/61 (50%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F LG++GLLP +V+ +EQV+ + L K ++LM + + N LF
Sbjct: 16 GTAFTEAEREELGLNGLLPAKVQALQEQVDQTYAQFQSKVSNLEKRLFLMEIFNTNHVLF 75
Query: 251 Y 253
Y
Sbjct: 76 Y 76
>UniRef50_P36013 Cluster: NAD-dependent malic enzyme, mitochondrial
precursor; n=15; Saccharomycetales|Rep: NAD-dependent
malic enzyme, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 669
Score = 58.0 bits (134), Expect = 2e-07
Identities = 30/80 (37%), Positives = 48/80 (60%), Gaps = 1/80 (1%)
Frame = +1
Query: 268 NVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNW-PETDVRAIVVT 444
++ E++PI+YTPT G A + +R+P G+F+ I + + L + + DV IVV+
Sbjct: 178 HIKELVPIIYTPTEGDAIAAYSHRFRKPEGVFLDITEPDSIECRLATYGGDKDVDYIVVS 237
Query: 445 DGERILGLGDLGACGMGIPV 504
D E ILG+GD G G+ I +
Sbjct: 238 DSEGILGIGDQGIGGVRIAI 257
Score = 44.4 bits (100), Expect = 0.002
Identities = 19/38 (50%), Positives = 26/38 (68%)
Frame = +3
Query: 507 QLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 620
+LAL T GGI P + LP+ +DVGTN + + D LY+G
Sbjct: 259 KLALMTLCGGIHPGRVLPVCLDVGTNNKKLARDELYMG 296
Score = 33.9 bits (74), Expect = 3.2
Identities = 17/61 (27%), Positives = 29/61 (47%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F + LLPP+V T +EQ+E + + PL K ++ L +N+ L+
Sbjct: 112 GSAFTQEEREAFNLEALLPPQVNTLDEQLERSYKQLCYLKTPLAKNDFMTSLRVQNKVLY 171
Query: 251 Y 253
+
Sbjct: 172 F 172
>UniRef50_A5C6I9 Cluster: Malic enzyme; n=1; Vitis vinifera|Rep:
Malic enzyme - Vitis vinifera (Grape)
Length = 498
Score = 56.8 bits (131), Expect = 4e-07
Identities = 26/50 (52%), Positives = 33/50 (66%)
Frame = +3
Query: 474 LGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
LG G P G+L +Y A GI P + LPI +DVGTN Q +L+D LY+GL
Sbjct: 58 LGVQGIGIPIGKLDMYVAAAGINPQRILPIMLDVGTNNQRLLEDRLYLGL 107
Score = 49.6 bits (113), Expect = 6e-05
Identities = 23/48 (47%), Positives = 31/48 (64%)
Frame = +1
Query: 364 ITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVG 507
IT + H++ + + V IV+TDG RILGLGDLG G+GIP+G
Sbjct: 21 ITXNGIXHIWSDIGSXDLCQVDMIVITDGSRILGLGDLGVQGIGIPIG 68
>UniRef50_Q8Y5Y8 Cluster: Lmo1915 protein; n=15; Firmicutes|Rep:
Lmo1915 protein - Listeria monocytogenes
Length = 547
Score = 56.4 bits (130), Expect = 5e-07
Identities = 31/86 (36%), Positives = 48/86 (55%), Gaps = 3/86 (3%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRP-RGLFITIHDKGHVYDVLKNWPETD--VR 429
V NV + +PI+YTPT+G A ++ Y P LF+ + +KN+ + + +
Sbjct: 81 VTKNVTDYLPIIYTPTIGDAVIQYHKDYTAPDEALFVDAFAPEKLSASIKNYAKNNPNID 140
Query: 430 AIVVTDGERILGLGDLGACGMGIPVG 507
IV+TDGE +LG+GD G+ I VG
Sbjct: 141 MIVITDGEGVLGIGDWSVNGVKIAVG 166
Score = 54.0 bits (124), Expect = 3e-06
Identities = 22/53 (41%), Positives = 35/53 (66%)
Frame = +3
Query: 462 GSWRLGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 620
G W + ++ G+LA+YT G+ P + LP+ ID GTN +++L+DPLY+G
Sbjct: 154 GDWSVNGVKIA--VGKLAVYTVAAGLAPDRVLPVVIDAGTNNETLLNDPLYLG 204
Score = 40.7 bits (91), Expect = 0.028
Identities = 20/61 (32%), Positives = 31/61 (50%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F + + GLLPP ++T E+Q + I+ E PL+K+ L L + N L+
Sbjct: 18 GTAFSKEERASYQLDGLLPPIIETIEQQAVRIETQIENLETPLHKHRLLTNLYNENRTLY 77
Query: 251 Y 253
Y
Sbjct: 78 Y 78
Score = 33.5 bits (73), Expect = 4.2
Identities = 15/29 (51%), Positives = 20/29 (68%)
Frame = +3
Query: 33 SGLDHLKHPGLNKGMAFTIEERQSWGSTG 119
SG D++ +P LNKG AF+ EER S+ G
Sbjct: 5 SGFDYMNNPLLNKGTAFSKEERASYQLDG 33
>UniRef50_A4RZU1 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus lucimarinus CCE9901
Length = 539
Score = 56.4 bits (130), Expect = 5e-07
Identities = 22/40 (55%), Positives = 29/40 (72%)
Frame = +3
Query: 504 GQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
G++ LYT G++P CLP+ +DVGTN Q +LDDP Y GL
Sbjct: 151 GKILLYTVCAGVRPSACLPVCLDVGTNNQRLLDDPNYKGL 190
Score = 47.2 bits (107), Expect = 3e-04
Identities = 41/107 (38%), Positives = 49/107 (45%), Gaps = 30/107 (28%)
Frame = +1
Query: 277 EMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLK-NWPE---TDVRAIVVT 444
E+MP VYTPTVG AC+K+ + G++IT D G V L+ +W RA
Sbjct: 45 ELMPFVYTPTVGEACEKYHRLGIETNGVYITADDAGRVGAKLRGHWDRAAAARARAREGL 104
Query: 445 DGE--------------------------RILGLGDLGACGMGIPVG 507
DGE RILGLGDLGA GMGI G
Sbjct: 105 DGEAAKRRGVDRRARADDGVAVAVVTDGERILGLGDLGAGGMGISEG 151
>UniRef50_Q7K3R0 Cluster: Malic enzyme; n=2; Sophophora|Rep: Malic
enzyme - Drosophila melanogaster (Fruit fly)
Length = 633
Score = 56.4 bits (130), Expect = 5e-07
Identities = 27/61 (44%), Positives = 35/61 (57%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F VL IHGLLP V+T +EQ E+C ++ + N + +YIYL L RN LF
Sbjct: 84 GLAFTLNERRVLSIHGLLPVAVRTIDEQAEICSNLLESFTNNVQQYIYLTYLSRRNRRLF 143
Query: 251 Y 253
Y
Sbjct: 144 Y 144
Score = 53.6 bits (123), Expect = 4e-06
Identities = 24/59 (40%), Positives = 36/59 (61%)
Frame = +1
Query: 334 LVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGN 510
+++ +GL+I I D GHV +L NWP VR ++V++G +L +GDLG M I N
Sbjct: 172 MIHSMGQGLYICIKDLGHVSQILSNWPFRCVRCLLVSNGASVLSVGDLGVDEMPILFSN 230
Score = 45.2 bits (102), Expect = 0.001
Identities = 17/31 (54%), Positives = 23/31 (74%)
Frame = +3
Query: 531 GGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
GGI P CL + +DVGTN + +L+DP+Y GL
Sbjct: 238 GGIHPAYCLAVMLDVGTNNEELLNDPMYTGL 268
>UniRef50_Q2HCG7 Cluster: Malic enzyme; n=1; Chaetomium
globosum|Rep: Malic enzyme - Chaetomium globosum (Soil
fungus)
Length = 586
Score = 54.4 bits (125), Expect = 2e-06
Identities = 36/96 (37%), Positives = 49/96 (51%), Gaps = 20/96 (20%)
Frame = +1
Query: 277 EMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNW-PETDVRAIVVT--- 444
+M +VYTPT G A + F ++RRP+G+F+ +HD V+ L W D+ IVVT
Sbjct: 106 KMFSVVYTPTEGDAIENFSRLFRRPQGVFLNVHDCDRVHHDLSLWGMPDDIDYIVVTGAT 165
Query: 445 ----------------DGERILGLGDLGACGMGIPV 504
DGE ILG+GD G G+ I V
Sbjct: 166 FHPRARSRLRYQLTKLDGEEILGIGDQGCGGILISV 201
Score = 48.8 bits (111), Expect = 1e-04
Identities = 19/39 (48%), Positives = 30/39 (76%)
Frame = +3
Query: 507 QLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
+LAL T GI P++ LP+ +D GT+ +++L+DPLY+GL
Sbjct: 203 KLALMTLCAGIHPNRVLPVVLDCGTDNETLLNDPLYLGL 241
>UniRef50_Q8S484 Cluster: Putative NADP-dependent malic enzyme; n=1;
Zea mays|Rep: Putative NADP-dependent malic enzyme - Zea
mays (Maize)
Length = 309
Score = 53.6 bits (123), Expect = 4e-06
Identities = 23/33 (69%), Positives = 26/33 (78%)
Frame = +1
Query: 382 GHVYDVLKNWPETDVRAIVVTDGERILGLGDLG 480
G V DVLKNWP +++ I VTD ERILGLGDLG
Sbjct: 249 GKVLDVLKNWPHRNIQVIFVTDSERILGLGDLG 281
>UniRef50_Q5KEY3 Cluster: Malic enzyme; n=1; Filobasidiella
neoformans|Rep: Malic enzyme - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 629
Score = 47.6 bits (108), Expect = 2e-04
Identities = 30/94 (31%), Positives = 49/94 (52%), Gaps = 16/94 (17%)
Frame = +1
Query: 265 DNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK--------GHVYDVLK----- 405
D + E++ ++YTP A + ++RRP G +I+ ++ GH+ DV +
Sbjct: 129 DRLKELLGVLYTPGAAEAVAGYSSLFRRPVGCYISFPNQDGMRAQLEGHLTDVNRTADVA 188
Query: 406 ---NWPETDVRAIVVTDGERILGLGDLGACGMGI 498
N P+ + +VVTD E ILG+GD G G+ I
Sbjct: 189 YDSNKPDDAIDLVVVTDAEAILGIGDQGVGGITI 222
Score = 44.4 bits (100), Expect = 0.002
Identities = 17/36 (47%), Positives = 25/36 (69%)
Frame = +3
Query: 513 ALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 620
ALYT GI P++ LP+ +D GT+ ++ DPLY+G
Sbjct: 228 ALYTLGAGINPNRILPVVLDCGTDNHALFSDPLYMG 263
Score = 35.5 bits (78), Expect = 1.0
Identities = 18/61 (29%), Positives = 30/61 (49%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G GF + G+ G LP V + E+Q + + + + K+ +L L D+N+ LF
Sbjct: 64 GAGFTREERQIFGLEGFLPYDVHSLEKQCLRAYNQLCKQPSVILKHAFLASLRDQNQVLF 123
Query: 251 Y 253
Y
Sbjct: 124 Y 124
>UniRef50_Q9S4T5 Cluster: NAD-malate oxidoreductase homolog; n=15;
Legionellales|Rep: NAD-malate oxidoreductase homolog -
Legionella pneumophila
Length = 117
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/61 (37%), Positives = 32/61 (52%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F G+ G LP RV+T +EQV+ L Y L ++IYL L D+N+ +F
Sbjct: 35 GTAFTQEERKDFGLLGKLPHRVETLDEQVKRAYLQYSSYTTRLQQHIYLNNLHDKNQIVF 94
Query: 251 Y 253
Y
Sbjct: 95 Y 95
Score = 35.1 bits (77), Expect = 1.4
Identities = 25/64 (39%), Positives = 34/64 (53%), Gaps = 5/64 (7%)
Frame = +3
Query: 24 SGLSGLDHLKHPGLNKGMAFTIEERQSWGSTGCYHH-----ESRRKRSRLNYASSRSTDT 188
+ L G L P LNKG AFT EER+ +G G H + + KR+ L Y SS +T
Sbjct: 19 TSLCGKPLLTTPQLNKGTAFTQEERKDFGLLGKLPHRVETLDEQVKRAYLQY-SSYTTRL 77
Query: 189 KIHL 200
+ H+
Sbjct: 78 QQHI 81
>UniRef50_A5TVW2 Cluster: O-antigen N-acetylglucosamine transferase;
n=4; Fusobacterium nucleatum|Rep: O-antigen
N-acetylglucosamine transferase - Fusobacterium
nucleatum subsp. polymorphum ATCC 10953
Length = 801
Score = 34.7 bits (76), Expect = 1.8
Identities = 14/42 (33%), Positives = 22/42 (52%)
Frame = +2
Query: 149 EQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFYLSSRITW 274
E+ C +DRYE + KY Y + L D + Y+ S++ W
Sbjct: 426 EEYGACLAGLDRYEEAIEKYKYALNLDDEEKDEAYIYSQLGW 467
>UniRef50_Q116W6 Cluster: Putative uncharacterized protein; n=1;
Trichodesmium erythraeum IMS101|Rep: Putative
uncharacterized protein - Trichodesmium erythraeum
(strain IMS101)
Length = 1107
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/59 (30%), Positives = 33/59 (55%), Gaps = 1/59 (1%)
Frame = +2
Query: 98 SVLGIHGL-LPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFYLSSRIT 271
++LGI + LP ++K E + + +L+I NP+ I + G L N ++F + R+T
Sbjct: 643 NLLGIATMMLPTKLKDNYEPIAMAELAIAGRFNPMEGVILIQGQLTENSYIFSRNCRLT 701
>UniRef50_Q5SLE4 Cluster: CBS domain protein; n=7; Bacteria|Rep: CBS
domain protein - Thermus thermophilus (strain HB8 / ATCC
27634 / DSM 579)
Length = 143
Score = 33.9 bits (74), Expect = 3.2
Identities = 14/33 (42%), Positives = 22/33 (66%)
Frame = +1
Query: 370 IHDKGHVYDVLKNWPETDVRAIVVTDGERILGL 468
IH + V D L+ E D+ A++V +GER+LG+
Sbjct: 17 IHPEATVLDALRKLAEHDIGALLVMEGERLLGI 49
>UniRef50_O31597 Cluster: YjbA protein; n=19; Bacillaceae|Rep: YjbA
protein - Bacillus subtilis
Length = 250
Score = 33.9 bits (74), Expect = 3.2
Identities = 24/63 (38%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Frame = +1
Query: 349 PRGLFITIHDKGHVYDVLKNWPETDVR-AIVVTDGERILGLGDLGACGMGIPVGNSRSTP 525
P+GL +H K ++ KN T + VVTDG IL + +G IPV SR P
Sbjct: 60 PKGLLEDVHQKSYIR---KNHERTKLEYCFVVTDGIGILAVDTIGYT---IPVRKSRLIP 113
Query: 526 RSE 534
R E
Sbjct: 114 RQE 116
>UniRef50_Q18AX8 Cluster: Glycerol dehydratase; n=5;
Clostridiaceae|Rep: Glycerol dehydratase - Clostridium
difficile (strain 630)
Length = 790
Score = 33.5 bits (73), Expect = 4.2
Identities = 21/59 (35%), Positives = 27/59 (45%)
Frame = -3
Query: 407 FLRTSYTCPLSWIVMKRPLGRRYTRPNF*QARPTVGVYTIGIISATLSATKGRTDAHCG 231
F+ S P IV P GR+ T+P P VG T ++A SA+K D H G
Sbjct: 641 FMGISNYVPTGKIVGATPCGRKATKPLTEGVSPFVGTDTTSPLAAMKSASKINHDVHTG 699
>UniRef50_Q1EI20 Cluster: Putative uncharacterized protein; n=2;
root|Rep: Putative uncharacterized protein - uncultured
organism
Length = 302
Score = 32.7 bits (71), Expect = 7.3
Identities = 10/20 (50%), Positives = 16/20 (80%)
Frame = +1
Query: 355 GLFITIHDKGHVYDVLKNWP 414
G+++TI + G + D+LKNWP
Sbjct: 210 GVYLTIREPGQITDILKNWP 229
>UniRef50_A0WC26 Cluster: Multi-sensor hybrid histidine kinase
precursor; n=2; Geobacter lovleyi SZ|Rep: Multi-sensor
hybrid histidine kinase precursor - Geobacter lovleyi SZ
Length = 1007
Score = 32.7 bits (71), Expect = 7.3
Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Frame = +1
Query: 310 GLACQKFGLVYRRPRGL-FITIHDKGHVYDVLKNWPETDVRAIVVTDG 450
G+ K +YR R FI HD+ H+++ +KN PE + IV DG
Sbjct: 198 GIFDSKGVFLYRTARANEFIGKHDQPHLFEQMKNGPEEGIIDIVSNDG 245
>UniRef50_Q7QFF8 Cluster: ENSANGP00000020727; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000020727 - Anopheles gambiae
str. PEST
Length = 378
Score = 32.7 bits (71), Expect = 7.3
Identities = 27/87 (31%), Positives = 38/87 (43%)
Frame = +3
Query: 342 PPTKGPLHHDPR*GTCIRCS*ELAGDGRPRHCCNRRRTYSGSWRLGRMRDGHPCGQLALY 521
PP +G HDP C R + AG +HCC+ G R DG P AL+
Sbjct: 172 PPERGGPSHDPPGANCDR---QRAGGLVCKHCCS-----LGDIASERRPDGGPAAGPALH 223
Query: 522 TALGGIKPHQCLPITIDVGTNTQSMLD 602
+L C + DVG+N S+++
Sbjct: 224 KSLDTC----CHVLLDDVGSNVSSLVN 246
>UniRef50_A3GHR3 Cluster: Vacuolar diacylglycerol pyrophosphate
phosphatase; n=7; Saccharomycetales|Rep: Vacuolar
diacylglycerol pyrophosphate phosphatase - Pichia
stipitis (Yeast)
Length = 281
Score = 32.7 bits (71), Expect = 7.3
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 8/83 (9%)
Frame = +1
Query: 355 GLFITIHDKGHVYDVLKNW---PETDVRA-IVVTDGERILGLGDLGAC----GMGIPVGN 510
GL +++ G V D+LKNW P D A G + L D+ C G+ I
Sbjct: 112 GLVVSLSINGVVTDILKNWISRPRPDFLARCGAKPGTPVGKLVDVSVCTAPLGITILTDG 171
Query: 511 SRSTPRSEASSRISVCPSLSTWV 579
RSTP +S S L+ W+
Sbjct: 172 MRSTPSGHSSISFSGLTFLTLWL 194
>UniRef50_UPI0000EBCB21 Cluster: PREDICTED: similar to FELE-2,
partial; n=1; Bos taurus|Rep: PREDICTED: similar to
FELE-2, partial - Bos taurus
Length = 1955
Score = 32.3 bits (70), Expect = 9.7
Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 4/38 (10%)
Frame = +3
Query: 291 CVHSDGWPG----LSEVRPCVPPTKGPLHHDPR*GTCI 392
CV +GW G SE+ PC+ P+ G HH+ TC+
Sbjct: 299 CVCREGWTGDGRDCSEINPCLLPSAGSCHHN---ATCL 333
>UniRef50_Q4T8X4 Cluster: Chromosome undetermined SCAF7707, whole
genome shotgun sequence; n=3; Coelomata|Rep: Chromosome
undetermined SCAF7707, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 720
Score = 32.3 bits (70), Expect = 9.7
Identities = 23/78 (29%), Positives = 38/78 (48%)
Frame = +1
Query: 370 IHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGNSRSTPRSEASSRI 549
+ D+G V + LK++ + +VRA+ R LGL + P +S ++ +
Sbjct: 413 LRDEGKVIEPLKDFHKDEVRAL-----GRELGLPEEIVSRHPFPGKSSAREQKTHTRPEV 467
Query: 550 SVCPSLSTWVRTPSRCWT 603
VCPS S+ +R PS T
Sbjct: 468 LVCPSESSVLRNPSSART 485
>UniRef50_Q2XQY7 Cluster: Intraflagellar transport protein 57; n=1;
Chlamydomonas reinhardtii|Rep: Intraflagellar transport
protein 57 - Chlamydomonas reinhardtii
Length = 469
Score = 32.3 bits (70), Expect = 9.7
Identities = 14/53 (26%), Positives = 27/53 (50%)
Frame = +2
Query: 119 LLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFYLSSRITWL 277
+L ++K + + C+ Y PL++ + + L + +E FY +S TWL
Sbjct: 78 MLADKLKLLNYEADFCRKK-KPYRKPLSRLYFAVPLANSSEQFFYFTSLATWL 129
>UniRef50_Q583W5 Cluster: Putative uncharacterized protein; n=2;
Trypanosoma|Rep: Putative uncharacterized protein -
Trypanosoma brucei
Length = 2070
Score = 32.3 bits (70), Expect = 9.7
Identities = 18/60 (30%), Positives = 26/60 (43%)
Frame = +1
Query: 415 ETDVRAIVVTDGERILGLGDLGACGMGIPVGNSRSTPRSEASSRISVCPSLSTWVRTPSR 594
+ DV + + G +I G + G G S+ PR SR+ +ST V PSR
Sbjct: 1390 QQDVTSFLQVTGTKISAFGTNASLTRGRLTGGSKRDPRGAVVSRMDATGVISTLVEAPSR 1449
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 718,544,736
Number of Sequences: 1657284
Number of extensions: 16256222
Number of successful extensions: 50315
Number of sequences better than 10.0: 73
Number of HSP's better than 10.0 without gapping: 47710
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 50276
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 45636850930
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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