Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= e40h0726
(625 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X79440-1|CAA55956.1| 604|Homo sapiens malate dehydrogenase (oxa... 137 3e-32
BC022472-1|AAH22472.1| 604|Homo sapiens malic enzyme 3, NADP(+)... 137 3e-32
AY424278-1|AAR04784.1| 259|Homo sapiens mitochondrial NADP(+)-d... 137 3e-32
AK092181-1|BAC03822.1| 252|Homo sapiens protein ( Homo sapiens ... 137 3e-32
X77244-1|CAA54460.1| 572|Homo sapiens malate dehydrogenase (oxa... 134 3e-31
U43944-1|AAC50613.1| 565|Homo sapiens cytosolic NADP(+)-depende... 134 3e-31
L34035-1|AAB01380.1| 572|Homo sapiens NADP-dependent malic enzy... 134 3e-31
BC025246-1|AAH25246.1| 572|Homo sapiens malic enzyme 1, NADP(+)... 134 3e-31
AL391416-2|CAH73129.1| 572|Homo sapiens malic enzyme 1, NADP(+)... 134 3e-31
AL136970-1|CAC19505.2| 572|Homo sapiens malic enzyme 1, NADP(+)... 134 3e-31
AL049699-1|CAI22634.1| 572|Homo sapiens malic enzyme 1, NADP(+)... 134 3e-31
AK223417-1|BAD97137.1| 572|Homo sapiens cytosolic malic enzyme ... 134 3e-31
M55905-1|AAA36197.1| 584|Homo sapiens mitochondrial NAD(P)+ -de... 131 2e-30
BC000147-1|AAH00147.1| 479|Homo sapiens ME2 protein protein. 131 2e-30
AB045122-1|BAB40980.1| 44|Homo sapiens ME2 protein. 33 1.1
>X79440-1|CAA55956.1| 604|Homo sapiens malate dehydrogenase
(oxaloacetate decarboxylating) (NADP+) protein.
Length = 604
Score = 137 bits (331), Expect = 3e-32
Identities = 59/83 (71%), Positives = 71/83 (85%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
+ +V + MPIVYTPTVGLACQ +GL +RRPRGLFITIHDKGH+ +L +WPE +++A+V
Sbjct: 125 LTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKAVV 184
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTDGERILGLGDLG GMGIPVG
Sbjct: 185 VTDGERILGLGDLGCYGMGIPVG 207
Score = 70.9 bits (166), Expect = 3e-12
Identities = 31/50 (62%), Positives = 37/50 (74%)
Frame = +3
Query: 474 LGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
LG G P G+LALYTA GG+ P QCLP+ +DVGTN + +L DPLYIGL
Sbjct: 197 LGCYGMGIPVGKLALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGL 246
Score = 51.6 bits (118), Expect = 2e-06
Identities = 27/61 (44%), Positives = 35/61 (57%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F LGIHGL+PP +Q+ Q+ +R ++ L+KYI LM L DRNE LF
Sbjct: 62 GMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNEKLF 121
Query: 251 Y 253
Y
Sbjct: 122 Y 122
Score = 35.1 bits (77), Expect = 0.20
Identities = 16/28 (57%), Positives = 19/28 (67%)
Frame = +3
Query: 36 GLDHLKHPGLNKGMAFTIEERQSWGSTG 119
G D ++P LNKGMAFT+EER G G
Sbjct: 50 GYDVTRNPHLNKGMAFTLEERLQLGIHG 77
>BC022472-1|AAH22472.1| 604|Homo sapiens malic enzyme 3,
NADP(+)-dependent, mitochondrial protein.
Length = 604
Score = 137 bits (331), Expect = 3e-32
Identities = 59/83 (71%), Positives = 71/83 (85%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
+ +V + MPIVYTPTVGLACQ +GL +RRPRGLFITIHDKGH+ +L +WPE +++A+V
Sbjct: 125 LTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKAVV 184
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTDGERILGLGDLG GMGIPVG
Sbjct: 185 VTDGERILGLGDLGCYGMGIPVG 207
Score = 70.9 bits (166), Expect = 3e-12
Identities = 31/50 (62%), Positives = 37/50 (74%)
Frame = +3
Query: 474 LGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
LG G P G+LALYTA GG+ P QCLP+ +DVGTN + +L DPLYIGL
Sbjct: 197 LGCYGMGIPVGKLALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGL 246
Score = 49.6 bits (113), Expect = 9e-06
Identities = 27/61 (44%), Positives = 34/61 (55%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F LGIHGL+PP Q+ Q+ +R ++ L+KYI LM L DRNE LF
Sbjct: 62 GMAFTLEERLQLGIHGLIPPCFLGQDVQLLRIMGYYERQQSDLDKYIILMTLQDRNEKLF 121
Query: 251 Y 253
Y
Sbjct: 122 Y 122
Score = 35.1 bits (77), Expect = 0.20
Identities = 16/28 (57%), Positives = 19/28 (67%)
Frame = +3
Query: 36 GLDHLKHPGLNKGMAFTIEERQSWGSTG 119
G D ++P LNKGMAFT+EER G G
Sbjct: 50 GYDVTRNPHLNKGMAFTLEERLQLGIHG 77
>AY424278-1|AAR04784.1| 259|Homo sapiens mitochondrial
NADP(+)-dependent malic enzyme 3 protein.
Length = 259
Score = 137 bits (331), Expect = 3e-32
Identities = 59/83 (71%), Positives = 71/83 (85%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
+ +V + MPIVYTPTVGLACQ +GL +RRPRGLFITIHDKGH+ +L +WPE +++A+V
Sbjct: 63 LTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKAVV 122
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTDGERILGLGDLG GMGIPVG
Sbjct: 123 VTDGERILGLGDLGCYGMGIPVG 145
Score = 70.9 bits (166), Expect = 3e-12
Identities = 31/50 (62%), Positives = 37/50 (74%)
Frame = +3
Query: 474 LGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
LG G P G+LALYTA GG+ P QCLP+ +DVGTN + +L DPLYIGL
Sbjct: 135 LGCYGMGIPVGKLALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGL 184
Score = 51.2 bits (117), Expect = 3e-06
Identities = 25/50 (50%), Positives = 33/50 (66%)
Frame = +2
Query: 104 LGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFY 253
LGIHGL+PP +Q+ Q+ +R ++ L+KYI LM L DRNE LFY
Sbjct: 11 LGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNEKLFY 60
>AK092181-1|BAC03822.1| 252|Homo sapiens protein ( Homo sapiens
cDNA FLJ34862 fis, clone NT2NE2013547, highly similar to
NADP-DEPENDENT MALIC ENZYME, MITOCHONDRIAL PRECURSOR (EC
1.1.1.40). ).
Length = 252
Score = 137 bits (331), Expect = 3e-32
Identities = 59/83 (71%), Positives = 71/83 (85%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
+ +V + MPIVYTPTVGLACQ +GL +RRPRGLFITIHDKGH+ +L +WPE +++A+V
Sbjct: 63 LTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKAVV 122
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTDGERILGLGDLG GMGIPVG
Sbjct: 123 VTDGERILGLGDLGCYGMGIPVG 145
Score = 70.9 bits (166), Expect = 3e-12
Identities = 31/50 (62%), Positives = 37/50 (74%)
Frame = +3
Query: 474 LGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
LG G P G+LALYTA GG+ P QCLP+ +DVGTN + +L DPLYIGL
Sbjct: 135 LGCYGMGIPVGKLALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGL 184
Score = 51.2 bits (117), Expect = 3e-06
Identities = 25/50 (50%), Positives = 33/50 (66%)
Frame = +2
Query: 104 LGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFY 253
LGIHGL+PP +Q+ Q+ +R ++ L+KYI LM L DRNE LFY
Sbjct: 11 LGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNEKLFY 60
>X77244-1|CAA54460.1| 572|Homo sapiens malate dehydrogenase
(oxaloacetate decarboxylating) (NADP+) protein.
Length = 572
Score = 134 bits (323), Expect = 3e-31
Identities = 58/83 (69%), Positives = 70/83 (84%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
+ ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+GH+ VL WPE ++AIV
Sbjct: 90 LTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASVLNAWPEDVIKAIV 149
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTDGERILGLGDLG GMGIPVG
Sbjct: 150 VTDGERILGLGDLGCNGMGIPVG 172
Score = 66.5 bits (155), Expect = 7e-11
Identities = 27/44 (61%), Positives = 34/44 (77%)
Frame = +3
Query: 492 GHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
G P G+LALYTA GG+ P +CLP+ +DVGT + +L DPLYIGL
Sbjct: 168 GIPVGKLALYTACGGMNPQECLPVILDVGTENEELLKDPLYIGL 211
Score = 48.4 bits (110), Expect = 2e-05
Identities = 23/50 (46%), Positives = 30/50 (60%)
Frame = +2
Query: 104 LGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFY 253
L IHGLLPP +QE QV + + + ++Y+ LM L DRNE LFY
Sbjct: 38 LNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFY 87
>U43944-1|AAC50613.1| 565|Homo sapiens cytosolic NADP(+)-dependent
malic enzyme protein.
Length = 565
Score = 134 bits (323), Expect = 3e-31
Identities = 58/83 (69%), Positives = 70/83 (84%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
+ ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+GH+ VL WPE ++AIV
Sbjct: 83 LTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASVLNAWPEDVIKAIV 142
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTDGERILGLGDLG GMGIPVG
Sbjct: 143 VTDGERILGLGDLGCNGMGIPVG 165
Score = 66.5 bits (155), Expect = 7e-11
Identities = 27/44 (61%), Positives = 34/44 (77%)
Frame = +3
Query: 492 GHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
G P G+LALYTA GG+ P +CLP+ +DVGT + +L DPLYIGL
Sbjct: 161 GIPVGKLALYTACGGMNPQECLPVILDVGTENEELLKDPLYIGL 204
Score = 48.4 bits (110), Expect = 2e-05
Identities = 23/50 (46%), Positives = 30/50 (60%)
Frame = +2
Query: 104 LGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFY 253
L IHGLLPP +QE QV + + + ++Y+ LM L DRNE LFY
Sbjct: 31 LNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFY 80
>L34035-1|AAB01380.1| 572|Homo sapiens NADP-dependent malic enzyme
protein.
Length = 572
Score = 134 bits (323), Expect = 3e-31
Identities = 58/83 (69%), Positives = 70/83 (84%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
+ ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+GH+ VL WPE ++AIV
Sbjct: 90 LTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASVLNAWPEDVIKAIV 149
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTDGERILGLGDLG GMGIPVG
Sbjct: 150 VTDGERILGLGDLGCNGMGIPVG 172
Score = 66.5 bits (155), Expect = 7e-11
Identities = 27/44 (61%), Positives = 34/44 (77%)
Frame = +3
Query: 492 GHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
G P G+LALYTA GG+ P +CLP+ +DVGT + +L DPLYIGL
Sbjct: 168 GIPVGKLALYTACGGMNPQECLPVILDVGTENEELLKDPLYIGL 211
Score = 48.4 bits (110), Expect = 2e-05
Identities = 23/50 (46%), Positives = 30/50 (60%)
Frame = +2
Query: 104 LGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFY 253
L IHGLLPP +QE QV + + + ++Y+ LM L DRNE LFY
Sbjct: 38 LNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFY 87
>BC025246-1|AAH25246.1| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 134 bits (323), Expect = 3e-31
Identities = 58/83 (69%), Positives = 70/83 (84%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
+ ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+GH+ VL WPE ++AIV
Sbjct: 90 LTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASVLNAWPEDVIKAIV 149
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTDGERILGLGDLG GMGIPVG
Sbjct: 150 VTDGERILGLGDLGCNGMGIPVG 172
Score = 66.5 bits (155), Expect = 7e-11
Identities = 27/44 (61%), Positives = 34/44 (77%)
Frame = +3
Query: 492 GHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
G P G+LALYTA GG+ P +CLP+ +DVGT + +L DPLYIGL
Sbjct: 168 GIPVGKLALYTACGGMNPQECLPVILDVGTENEELLKDPLYIGL 211
Score = 48.4 bits (110), Expect = 2e-05
Identities = 23/50 (46%), Positives = 30/50 (60%)
Frame = +2
Query: 104 LGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFY 253
L IHGLLPP +QE QV + + + ++Y+ LM L DRNE LFY
Sbjct: 38 LNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFY 87
>AL391416-2|CAH73129.1| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 134 bits (323), Expect = 3e-31
Identities = 58/83 (69%), Positives = 70/83 (84%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
+ ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+GH+ VL WPE ++AIV
Sbjct: 90 LTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASVLNAWPEDVIKAIV 149
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTDGERILGLGDLG GMGIPVG
Sbjct: 150 VTDGERILGLGDLGCNGMGIPVG 172
Score = 66.5 bits (155), Expect = 7e-11
Identities = 27/44 (61%), Positives = 34/44 (77%)
Frame = +3
Query: 492 GHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
G P G+LALYTA GG+ P +CLP+ +DVGT + +L DPLYIGL
Sbjct: 168 GIPVGKLALYTACGGMNPQECLPVILDVGTENEELLKDPLYIGL 211
Score = 48.4 bits (110), Expect = 2e-05
Identities = 23/50 (46%), Positives = 30/50 (60%)
Frame = +2
Query: 104 LGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFY 253
L IHGLLPP +QE QV + + + ++Y+ LM L DRNE LFY
Sbjct: 38 LNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFY 87
>AL136970-1|CAC19505.2| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 134 bits (323), Expect = 3e-31
Identities = 58/83 (69%), Positives = 70/83 (84%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
+ ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+GH+ VL WPE ++AIV
Sbjct: 90 LTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASVLNAWPEDVIKAIV 149
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTDGERILGLGDLG GMGIPVG
Sbjct: 150 VTDGERILGLGDLGCNGMGIPVG 172
Score = 66.5 bits (155), Expect = 7e-11
Identities = 27/44 (61%), Positives = 34/44 (77%)
Frame = +3
Query: 492 GHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
G P G+LALYTA GG+ P +CLP+ +DVGT + +L DPLYIGL
Sbjct: 168 GIPVGKLALYTACGGMNPQECLPVILDVGTENEELLKDPLYIGL 211
Score = 48.4 bits (110), Expect = 2e-05
Identities = 23/50 (46%), Positives = 30/50 (60%)
Frame = +2
Query: 104 LGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFY 253
L IHGLLPP +QE QV + + + ++Y+ LM L DRNE LFY
Sbjct: 38 LNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFY 87
>AL049699-1|CAI22634.1| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 134 bits (323), Expect = 3e-31
Identities = 58/83 (69%), Positives = 70/83 (84%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
+ ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+GH+ VL WPE ++AIV
Sbjct: 90 LTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASVLNAWPEDVIKAIV 149
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTDGERILGLGDLG GMGIPVG
Sbjct: 150 VTDGERILGLGDLGCNGMGIPVG 172
Score = 66.5 bits (155), Expect = 7e-11
Identities = 27/44 (61%), Positives = 34/44 (77%)
Frame = +3
Query: 492 GHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
G P G+LALYTA GG+ P +CLP+ +DVGT + +L DPLYIGL
Sbjct: 168 GIPVGKLALYTACGGMNPQECLPVILDVGTENEELLKDPLYIGL 211
Score = 48.4 bits (110), Expect = 2e-05
Identities = 23/50 (46%), Positives = 30/50 (60%)
Frame = +2
Query: 104 LGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFY 253
L IHGLLPP +QE QV + + + ++Y+ LM L DRNE LFY
Sbjct: 38 LNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFY 87
>AK223417-1|BAD97137.1| 572|Homo sapiens cytosolic malic enzyme 1
variant protein.
Length = 572
Score = 134 bits (323), Expect = 3e-31
Identities = 58/83 (69%), Positives = 70/83 (84%)
Frame = +1
Query: 259 VADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIV 438
+ ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+GH+ VL WPE ++AIV
Sbjct: 90 LTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASVLNAWPEDVIKAIV 149
Query: 439 VTDGERILGLGDLGACGMGIPVG 507
VTDGERILGLGDLG GMGIPVG
Sbjct: 150 VTDGERILGLGDLGCNGMGIPVG 172
Score = 66.5 bits (155), Expect = 7e-11
Identities = 27/44 (61%), Positives = 34/44 (77%)
Frame = +3
Query: 492 GHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
G P G+LALYTA GG+ P +CLP+ +DVGT + +L DPLYIGL
Sbjct: 168 GIPVGKLALYTACGGMNPQECLPVILDVGTENEELLKDPLYIGL 211
Score = 48.4 bits (110), Expect = 2e-05
Identities = 23/50 (46%), Positives = 30/50 (60%)
Frame = +2
Query: 104 LGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFY 253
L IHGLLPP +QE QV + + + ++Y+ LM L DRNE LFY
Sbjct: 38 LNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFY 87
>M55905-1|AAA36197.1| 584|Homo sapiens mitochondrial NAD(P)+
-dependent malic enzyme protein.
Length = 584
Score = 131 bits (317), Expect = 2e-30
Identities = 55/81 (67%), Positives = 69/81 (85%)
Frame = +1
Query: 265 DNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVT 444
D++ +MPIVYTPTVGLAC ++G ++RRP+GLFI+I D+GHV ++ NWPE V+A+VVT
Sbjct: 102 DDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKAVVVT 161
Query: 445 DGERILGLGDLGACGMGIPVG 507
DGERILGLGDLG GMGIPVG
Sbjct: 162 DGERILGLGDLGVYGMGIPVG 182
Score = 60.9 bits (141), Expect = 4e-09
Identities = 26/61 (42%), Positives = 40/61 (65%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F + +LG+ GLLPP+++TQ+ Q ++ + +PL KYIY+MG+ +RNE LF
Sbjct: 37 GMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQERNEKLF 96
Query: 251 Y 253
Y
Sbjct: 97 Y 97
Score = 60.9 bits (141), Expect = 4e-09
Identities = 27/50 (54%), Positives = 35/50 (70%)
Frame = +3
Query: 474 LGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
LG G P G+L LYTA GI+P +CLP+ IDVGT+ ++L DP Y+GL
Sbjct: 172 LGVYGMGIPVGKLCLYTACAGIRPDRCLPVCIDVGTDNIALLKDPFYMGL 221
Score = 31.1 bits (67), Expect = 3.3
Identities = 13/22 (59%), Positives = 16/22 (72%)
Frame = +3
Query: 54 HPGLNKGMAFTIEERQSWGSTG 119
+P NKGMAFT++ERQ G G
Sbjct: 31 NPRTNKGMAFTLQERQMLGLQG 52
>BC000147-1|AAH00147.1| 479|Homo sapiens ME2 protein protein.
Length = 479
Score = 131 bits (317), Expect = 2e-30
Identities = 55/81 (67%), Positives = 69/81 (85%)
Frame = +1
Query: 265 DNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVT 444
D++ +MPIVYTPTVGLAC ++G ++RRP+GLFI+I D+GHV ++ NWPE V+A+VVT
Sbjct: 102 DDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKAVVVT 161
Query: 445 DGERILGLGDLGACGMGIPVG 507
DGERILGLGDLG GMGIPVG
Sbjct: 162 DGERILGLGDLGVYGMGIPVG 182
Score = 60.9 bits (141), Expect = 4e-09
Identities = 26/61 (42%), Positives = 40/61 (65%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 250
G F + +LG+ GLLPP+++TQ+ Q ++ + +PL KYIY+MG+ +RNE LF
Sbjct: 37 GMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQERNEKLF 96
Query: 251 Y 253
Y
Sbjct: 97 Y 97
Score = 60.9 bits (141), Expect = 4e-09
Identities = 27/50 (54%), Positives = 35/50 (70%)
Frame = +3
Query: 474 LGRMRDGHPCGQLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 623
LG G P G+L LYTA GI+P +CLP+ IDVGT+ ++L DP Y+GL
Sbjct: 172 LGVYGMGIPVGKLCLYTACAGIRPDRCLPVCIDVGTDNIALLKDPFYMGL 221
Score = 31.1 bits (67), Expect = 3.3
Identities = 13/22 (59%), Positives = 16/22 (72%)
Frame = +3
Query: 54 HPGLNKGMAFTIEERQSWGSTG 119
+P NKGMAFT++ERQ G G
Sbjct: 31 NPRTNKGMAFTLQERQMLGLQG 52
>AB045122-1|BAB40980.1| 44|Homo sapiens ME2 protein.
Length = 44
Score = 32.7 bits (71), Expect = 1.1
Identities = 14/43 (32%), Positives = 25/43 (58%)
Frame = +2
Query: 71 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPL 199
G F + +LG+ GLLPP+++TQ+ Q ++ + +PL
Sbjct: 1 GMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPL 43
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 108,107,428
Number of Sequences: 237096
Number of extensions: 2614426
Number of successful extensions: 6780
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 6384
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6778
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6747805200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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