Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= e40h0677
(680 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_A7T6B8 Cluster: Predicted protein; n=1; Nematostella ve... 137 2e-31
UniRef50_Q4S0L0 Cluster: Malic enzyme; n=2; Tetraodon nigrovirid... 133 3e-30
UniRef50_Q16798 Cluster: NADP-dependent malic enzyme, mitochondr... 131 1e-29
UniRef50_P23368 Cluster: NAD-dependent malic enzyme, mitochondri... 129 5e-29
UniRef50_Q5BX10 Cluster: Malic enzyme; n=1; Schistosoma japonicu... 128 1e-28
UniRef50_P48163 Cluster: NADP-dependent malic enzyme; n=63; Euka... 128 1e-28
UniRef50_P06801 Cluster: NADP-dependent malic enzyme; n=52; cell... 124 2e-27
UniRef50_A2ZQ54 Cluster: Malic enzyme; n=9; Oryza sativa|Rep: Ma... 123 5e-27
UniRef50_A0L5P5 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 120 3e-26
UniRef50_A7CWP9 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 120 4e-26
UniRef50_Q0AIF8 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 118 1e-25
UniRef50_Q89G76 Cluster: Malic enzyme; n=3; cellular organisms|R... 118 2e-25
UniRef50_P16243 Cluster: NADP-dependent malic enzyme, chloroplas... 113 3e-24
UniRef50_A7PC00 Cluster: Chromosome chr2 scaffold_11, whole geno... 110 4e-23
UniRef50_Q016K2 Cluster: NADP dependent malic enzyme; n=2; Ostre... 105 8e-22
UniRef50_Q8D911 Cluster: NAD-dependent malic enzyme; n=187; cell... 101 2e-20
UniRef50_A6SA55 Cluster: Malic enzyme; n=2; Sclerotiniaceae|Rep:... 100 4e-20
UniRef50_A7IMB8 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 98 2e-19
UniRef50_Q8I8I4 Cluster: Malic enzyme; n=4; Eukaryota|Rep: Malic... 98 2e-19
UniRef50_Q86NT5 Cluster: Malic enzyme; n=2; Drosophila melanogas... 97 3e-19
UniRef50_UPI0000D9F768 Cluster: PREDICTED: similar to Y48B6A.12,... 96 8e-19
UniRef50_A3QW96 Cluster: Malic enzyme; n=10; Tigriopus californi... 96 8e-19
UniRef50_P37221 Cluster: NAD-dependent malic enzyme 62 kDa isofo... 96 8e-19
UniRef50_Q4X1Z2 Cluster: NADP-dependent malic enzyme MaeA; n=11;... 94 2e-18
UniRef50_P78715 Cluster: Malic enzyme, hydrogenosomal precursor;... 94 3e-18
UniRef50_A1ZAF7 Cluster: Malic enzyme; n=5; Sophophora|Rep: Mali... 93 6e-18
UniRef50_Q01AM5 Cluster: NADP+-dependent malic enzyme; n=2; Ostr... 92 1e-17
UniRef50_Q00XN9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 90 5e-17
UniRef50_A3BK03 Cluster: Malic enzyme; n=2; Oryza sativa|Rep: Ma... 89 9e-17
UniRef50_Q875H8 Cluster: Malic enzyme; n=1; Mucor circinelloides... 88 2e-16
UniRef50_Q4PC56 Cluster: Malic enzyme; n=1; Ustilago maydis|Rep:... 87 3e-16
UniRef50_Q9HE50 Cluster: Malic enzyme; n=6; Pezizomycotina|Rep: ... 87 4e-16
UniRef50_A0Q531 Cluster: NAD-dependent malic enzyme; n=10; Franc... 85 1e-15
UniRef50_A4RQC9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 85 2e-15
UniRef50_Q5K758 Cluster: Malic enzyme; n=1; Filobasidiella neofo... 85 2e-15
UniRef50_Q9RYN4 Cluster: Malate oxidoreductase; n=6; Deinococci|... 84 3e-15
UniRef50_A2EKE3 Cluster: Malic enzyme; n=14; Trichomonadidae|Rep... 83 8e-15
UniRef50_A4RZU1 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 82 1e-14
UniRef50_A1SVL3 Cluster: Malic enzyme aka malate dehydrogenase (... 80 4e-14
UniRef50_A5C6I9 Cluster: Malic enzyme; n=1; Vitis vinifera|Rep: ... 80 4e-14
UniRef50_P45868 Cluster: Probable NAD-dependent malic enzyme 2; ... 80 4e-14
UniRef50_Q5CS07 Cluster: Malic enzyme; n=2; Cryptosporidium|Rep:... 79 7e-14
UniRef50_A6XP71 Cluster: Malic enzyme protein 2; n=2; Mucoromyco... 79 1e-13
UniRef50_Q4QAQ6 Cluster: Malic enzyme, putative; n=20; Trypanoso... 77 4e-13
UniRef50_Q7SHJ8 Cluster: Malic enzyme; n=12; Pezizomycotina|Rep:... 75 2e-12
UniRef50_A4SKB8 Cluster: NAD-dependent malic enzyme; n=2; Aeromo... 75 2e-12
UniRef50_Q5KBK5 Cluster: Nad-dependent malic enzyme, putative; n... 72 2e-11
UniRef50_Q95061 Cluster: Malic enzyme; n=2; Giardia intestinalis... 69 1e-10
UniRef50_Q6AL43 Cluster: Related to NAD-dependent malic enzyme; ... 68 2e-10
UniRef50_Q8Y5Y8 Cluster: Lmo1915 protein; n=15; Firmicutes|Rep: ... 68 2e-10
UniRef50_A3YYQ0 Cluster: Malate oxidoreductase; n=1; Synechococc... 68 2e-10
UniRef50_A2QY66 Cluster: Malic enzyme; n=2; cellular organisms|R... 67 4e-10
UniRef50_Q2HCG7 Cluster: Malic enzyme; n=1; Chaetomium globosum|... 66 6e-10
UniRef50_Q48796 Cluster: Malolactic enzyme; n=49; Bacteria|Rep: ... 63 5e-09
UniRef50_P40375 Cluster: NAD-dependent malic enzyme; n=3; Schizo... 62 9e-09
UniRef50_P36013 Cluster: NAD-dependent malic enzyme, mitochondri... 60 5e-08
UniRef50_Q5KEY3 Cluster: Malic enzyme; n=1; Filobasidiella neofo... 59 9e-08
UniRef50_Q7K3R0 Cluster: Malic enzyme; n=2; Sophophora|Rep: Mali... 56 8e-07
UniRef50_Q9S4T5 Cluster: NAD-malate oxidoreductase homolog; n=15... 48 2e-04
UniRef50_Q8S484 Cluster: Putative NADP-dependent malic enzyme; n... 45 0.002
UniRef50_UPI0000DB7FF6 Cluster: PREDICTED: hypothetical protein,... 42 0.011
UniRef50_UPI0000DA40E4 Cluster: PREDICTED: hypothetical protein;... 34 2.8
UniRef50_Q4SN44 Cluster: Chromosome 8 SCAF14543, whole genome sh... 34 2.8
UniRef50_A1CBX6 Cluster: RNA binding domain protein; n=1; Asperg... 34 3.7
UniRef50_UPI0000EB0F1E Cluster: UPI0000EB0F1E related cluster; n... 33 4.9
UniRef50_Q17IF3 Cluster: Putative uncharacterized protein; n=1; ... 33 4.9
UniRef50_Q7WLT2 Cluster: Putative uncharacterized protein; n=1; ... 33 6.4
UniRef50_Q6ZCE9 Cluster: Putative uncharacterized protein P0486F... 33 6.4
UniRef50_Q1EI20 Cluster: Putative uncharacterized protein; n=2; ... 33 8.5
UniRef50_A3K0U7 Cluster: Putative uncharacterized protein; n=2; ... 33 8.5
UniRef50_A0WC26 Cluster: Multi-sensor hybrid histidine kinase pr... 33 8.5
UniRef50_A0K1T3 Cluster: Allergen V5/Tpx-1 family protein precur... 33 8.5
UniRef50_Q9LT49 Cluster: Arabidopsis thaliana genomic DNA, chrom... 33 8.5
UniRef50_Q6ZSU3 Cluster: CDNA FLJ45206 fis, clone BRCAN2010581; ... 33 8.5
UniRef50_A1CKF3 Cluster: Stress response protein (Ish1), putativ... 33 8.5
>UniRef50_A7T6B8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 365
Score = 137 bits (332), Expect = 2e-31
Identities = 57/85 (67%), Positives = 74/85 (87%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
+YI LM LL+RNE LF+R + D E+MPIVYTPTVGLAC+K+G+++RRPRGLFI+IHDK
Sbjct: 71 KYIQLMALLERNESLFFRVLFDYTEELMPIVYTPTVGLACRKYGMIFRRPRGLFISIHDK 130
Query: 434 GHVYDVLKNWPETDVRAIVVTDGER 508
GH+ D++ NWP T+V+AIV+TDGER
Sbjct: 131 GHIRDIVSNWPTTEVKAIVMTDGER 155
Score = 98.3 bits (234), Expect = 2e-19
Identities = 42/56 (75%), Positives = 46/56 (82%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LGLGDLG CGMGIPVGKLALYT GGI P CLP+ IDVGTN + +LDDP YIG+R
Sbjct: 157 LGLGDLGCCGMGIPVGKLALYTVCGGIDPEGCLPVMIDVGTNNEELLDDPFYIGVR 212
Score = 35.1 bits (77), Expect = 1.6
Identities = 18/43 (41%), Positives = 22/43 (51%)
Frame = +3
Query: 123 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPL 251
G F +LGIHGLLPP V +QE Q + + R N L
Sbjct: 27 GLAFTLEERQILGIHGLLPPCVISQEIQAQRVYRELQRKPNDL 69
Score = 33.5 bits (73), Expect = 4.9
Identities = 15/30 (50%), Positives = 20/30 (66%)
Frame = +1
Query: 82 LSGLDHLKHPGLNKGMAFTIEERQSWGSTG 171
+ G D ++ LNKG+AFT+EERQ G G
Sbjct: 13 IRGTDIMRDSHLNKGLAFTLEERQILGIHG 42
>UniRef50_Q4S0L0 Cluster: Malic enzyme; n=2; Tetraodon
nigroviridis|Rep: Malic enzyme - Tetraodon nigroviridis
(Green puffer)
Length = 694
Score = 133 bits (322), Expect = 3e-30
Identities = 56/85 (65%), Positives = 71/85 (83%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
+YI LM L DRNE LFYR + ++ + MPIVYTPTVGLACQ++GL +RRPRGLFITIHD+
Sbjct: 118 KYILLMTLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYGLAFRRPRGLFITIHDR 177
Query: 434 GHVYDVLKNWPETDVRAIVVTDGER 508
GH+ +L +WPE D++A+VVTDGER
Sbjct: 178 GHIATMLNSWPEEDIKAVVVTDGER 202
Score = 51.6 bits (118), Expect = 2e-05
Identities = 32/66 (48%), Positives = 38/66 (57%), Gaps = 10/66 (15%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALY-----TALGGIKPHQC-----LPITIDVGTNTQSMLDDP 660
LGLGDLG+ GMGIPVGKLAL A + P P ++ G Q +LDDP
Sbjct: 204 LGLGDLGSYGMGIPVGKLALLHRLRRRAAAAVPPGAAGRGHRQPGSVPGGVCVQVLLDDP 263
Query: 661 LYIGLR 678
LYIGL+
Sbjct: 264 LYIGLK 269
Score = 36.3 bits (80), Expect = 0.69
Identities = 17/39 (43%), Positives = 23/39 (58%)
Frame = +1
Query: 55 SGDGQPTSGLSGLDHLKHPGLNKGMAFTIEERQSWGSTG 171
+ +G + G D ++P LNKGMAFT+EER G G
Sbjct: 51 ASEGSVRTKKRGYDITRNPHLNKGMAFTLEERLQMGIHG 89
Score = 32.7 bits (71), Expect = 8.5
Identities = 18/49 (36%), Positives = 24/49 (48%)
Frame = +3
Query: 123 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNSTSIL 269
G F +GIHGLLPP +Q+ QV S + NPL+ +L
Sbjct: 74 GMAFTLEERLQMGIHGLLPPCFLSQDVQVLRVMKSYETRSNPLDKYILL 122
>UniRef50_Q16798 Cluster: NADP-dependent malic enzyme, mitochondrial
precursor; n=15; Bilateria|Rep: NADP-dependent malic
enzyme, mitochondrial precursor - Homo sapiens (Human)
Length = 604
Score = 131 bits (317), Expect = 1e-29
Identities = 57/85 (67%), Positives = 70/85 (82%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
+YI LM L DRNE LFYR + +V + MPIVYTPTVGLACQ +GL +RRPRGLFITIHDK
Sbjct: 106 KYIILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDK 165
Query: 434 GHVYDVLKNWPETDVRAIVVTDGER 508
GH+ +L +WPE +++A+VVTDGER
Sbjct: 166 GHLATMLNSWPEDNIKAVVVTDGER 190
Score = 95.9 bits (228), Expect = 8e-19
Identities = 41/56 (73%), Positives = 47/56 (83%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LGLGDLG GMGIPVGKLALYTA GG+ P QCLP+ +DVGTN + +L DPLYIGL+
Sbjct: 192 LGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLK 247
Score = 35.1 bits (77), Expect = 1.6
Identities = 16/28 (57%), Positives = 19/28 (67%)
Frame = +1
Query: 88 GLDHLKHPGLNKGMAFTIEERQSWGSTG 171
G D ++P LNKGMAFT+EER G G
Sbjct: 50 GYDVTRNPHLNKGMAFTLEERLQLGIHG 77
>UniRef50_P23368 Cluster: NAD-dependent malic enzyme, mitochondrial
precursor; n=53; Eumetazoa|Rep: NAD-dependent malic
enzyme, mitochondrial precursor - Homo sapiens (Human)
Length = 584
Score = 129 bits (312), Expect = 5e-29
Identities = 52/85 (61%), Positives = 71/85 (83%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
+YIY+MG+ +RNE LFYR + D++ +MPIVYTPTVGLAC ++G ++RRP+GLFI+I D+
Sbjct: 81 KYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDR 140
Query: 434 GHVYDVLKNWPETDVRAIVVTDGER 508
GHV ++ NWPE V+A+VVTDGER
Sbjct: 141 GHVRSIVDNWPENHVKAVVVTDGER 165
Score = 85.0 bits (201), Expect = 2e-15
Identities = 37/55 (67%), Positives = 44/55 (80%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 675
LGLGDLG GMGIPVGKL LYTA GI+P +CLP+ IDVGT+ ++L DP Y+GL
Sbjct: 167 LGLGDLGVYGMGIPVGKLCLYTACAGIRPDRCLPVCIDVGTDNIALLKDPFYMGL 221
Score = 33.5 bits (73), Expect = 4.9
Identities = 15/51 (29%), Positives = 27/51 (52%)
Frame = +3
Query: 123 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNSTSILWG 275
G F + +LG+ GLLPP+++TQ+ Q ++ + +PL + G
Sbjct: 37 GMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMG 87
>UniRef50_Q5BX10 Cluster: Malic enzyme; n=1; Schistosoma
japonicum|Rep: Malic enzyme - Schistosoma japonicum
(Blood fluke)
Length = 216
Score = 128 bits (309), Expect = 1e-28
Identities = 54/85 (63%), Positives = 70/85 (82%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
+YIYL L DRNE LFY+ V ++V MP++YTPTVGLACQ++G+V+RRPRGL+ITIHD+
Sbjct: 110 RYIYLTSLQDRNEALFYKLVIEHVEYCMPLIYTPTVGLACQRYGVVFRRPRGLYITIHDR 169
Query: 434 GHVYDVLKNWPETDVRAIVVTDGER 508
H+ ++L NWPE V+AIV TDGER
Sbjct: 170 HHIPEILNNWPEPIVKAIVFTDGER 194
Score = 34.3 bits (75), Expect = 2.8
Identities = 16/29 (55%), Positives = 18/29 (62%)
Frame = +3
Query: 123 GYGFYHRRASVLGIHGLLPPRVKTQEEQV 209
G F +LGIHGLLPP V T E+QV
Sbjct: 66 GTAFTVNERQLLGIHGLLPPSVLTLEQQV 94
Score = 34.3 bits (75), Expect = 2.8
Identities = 14/16 (87%), Positives = 15/16 (93%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVG 558
LGLGDLGA GMGIP+G
Sbjct: 196 LGLGDLGAYGMGIPIG 211
>UniRef50_P48163 Cluster: NADP-dependent malic enzyme; n=63;
Eukaryota|Rep: NADP-dependent malic enzyme - Homo
sapiens (Human)
Length = 572
Score = 128 bits (309), Expect = 1e-28
Identities = 55/85 (64%), Positives = 69/85 (81%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
+Y+ LM L DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+
Sbjct: 71 RYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDR 130
Query: 434 GHVYDVLKNWPETDVRAIVVTDGER 508
GH+ VL WPE ++AIVVTDGER
Sbjct: 131 GHIASVLNAWPEDVIKAIVVTDGER 155
Score = 92.7 bits (220), Expect = 8e-18
Identities = 40/56 (71%), Positives = 46/56 (82%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LGLGDLG GMGIPVGKLALYTA GG+ P +CLP+ +DVGT + +L DPLYIGLR
Sbjct: 157 LGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVILDVGTENEELLKDPLYIGLR 212
>UniRef50_P06801 Cluster: NADP-dependent malic enzyme; n=52;
cellular organisms|Rep: NADP-dependent malic enzyme -
Mus musculus (Mouse)
Length = 572
Score = 124 bits (299), Expect = 2e-27
Identities = 55/85 (64%), Positives = 67/85 (78%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
+Y+ LM L DRNE LFY + +V + MPIVYTPTVGLACQ++ L +R+PRGLFI+IHDK
Sbjct: 71 RYLLLMDLQDRNEKLFYSVLMSDVEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDK 130
Query: 434 GHVYDVLKNWPETDVRAIVVTDGER 508
GH+ VL WPE V+AIVVTDGER
Sbjct: 131 GHIASVLNAWPEDVVKAIVVTDGER 155
Score = 97.5 bits (232), Expect = 3e-19
Identities = 43/56 (76%), Positives = 47/56 (83%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LGLGDLG GMGIPVGKLALYTA GG+ P QCLPIT+DVGT + +L DPLYIGLR
Sbjct: 157 LGLGDLGCNGMGIPVGKLALYTACGGVNPQQCLPITLDVGTENEELLKDPLYIGLR 212
>UniRef50_A2ZQ54 Cluster: Malic enzyme; n=9; Oryza sativa|Rep: Malic
enzyme - Oryza sativa subsp. japonica (Rice)
Length = 613
Score = 123 bits (296), Expect = 5e-27
Identities = 49/85 (57%), Positives = 71/85 (83%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
+Y+ +M L +RNE LFY+ + DNV E++P+VYTPTVG ACQK+G ++R+P+GL++++ DK
Sbjct: 156 RYMAMMDLQERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFRQPQGLYVSLKDK 215
Query: 434 GHVYDVLKNWPETDVRAIVVTDGER 508
G V DVL+NWPE +++ IVVTDGER
Sbjct: 216 GKVLDVLRNWPERNIQVIVVTDGER 240
Score = 95.5 bits (227), Expect = 1e-18
Identities = 42/56 (75%), Positives = 48/56 (85%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LGLGDLG GMGIPVGKL+LYTALGG++P CLPITIDVGTN + +L+D YIGLR
Sbjct: 242 LGLGDLGCQGMGIPVGKLSLYTALGGVRPSACLPITIDVGTNNEQLLNDEFYIGLR 297
>UniRef50_A0L5P5 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=1;
Magnetococcus sp. MC-1|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Magnetococcus
sp. (strain MC-1)
Length = 556
Score = 120 bits (289), Expect = 3e-26
Identities = 51/85 (60%), Positives = 67/85 (78%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
+YI+L GL +RNE LFYR V N+ EM+PI+YTPTVG ACQ +G ++RRP+G+FI+I+DK
Sbjct: 75 KYIFLTGLQERNETLFYRLVMTNIEEMLPIIYTPTVGKACQTYGHIFRRPQGMFISINDK 134
Query: 434 GHVYDVLKNWPETDVRAIVVTDGER 508
G + ++L NW DVR IVVTDG R
Sbjct: 135 GRIAELLGNWVHKDVRVIVVTDGSR 159
Score = 92.7 bits (220), Expect = 8e-18
Identities = 40/55 (72%), Positives = 48/55 (87%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 675
LGLGDLGA GMGIPVGKLALYTAL GI P CLP+T+D+GTN +++ +DPLY+GL
Sbjct: 161 LGLGDLGAHGMGIPVGKLALYTALAGIPPIHCLPVTLDMGTNNEALRNDPLYVGL 215
>UniRef50_A7CWP9 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=1;
Opitutaceae bacterium TAV2|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Opitutaceae
bacterium TAV2
Length = 561
Score = 120 bits (288), Expect = 4e-26
Identities = 60/115 (52%), Positives = 76/115 (66%)
Frame = +2
Query: 164 PRVVTTTSQDARGAG*TMQALDRQIRKST*QYIYLMGLLDRNEHLFYRFVADNVAEMMPI 343
PRV T Q+ R M I K YIYL L RNE LFYR + ++ EM+P+
Sbjct: 55 PRVFTLEQQEQRALN-AMAKKPSAIEK----YIYLTTLQSRNETLFYRLLTNHAEEMIPL 109
Query: 344 VYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGER 508
VYTPTVG AC ++G +RRPRGLFI+I D+G + ++L++WP TDVR IVVTDGER
Sbjct: 110 VYTPTVGQACLEYGANFRRPRGLFISIKDRGRIAEILRHWPITDVRMIVVTDGER 164
Score = 79.4 bits (187), Expect = 7e-14
Identities = 33/54 (61%), Positives = 42/54 (77%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 672
LGLGDLG GMGIPVGKLALY+A G+ P CLPI +D G + +++ +DPLY+G
Sbjct: 166 LGLGDLGVLGMGIPVGKLALYSACAGLHPSYCLPIALDAGIDNETLRNDPLYLG 219
Score = 34.3 bits (75), Expect = 2.8
Identities = 19/53 (35%), Positives = 22/53 (41%)
Frame = +3
Query: 48 MGLRGRTAHXXXXXXXXXXXXXXXXGYGFYHRRASVLGIHGLLPPRVKTQEEQ 206
+GL R A G F R LG+ GLLPPRV T E+Q
Sbjct: 11 LGLSARGARASLRGTALLGDSVLNKGTAFSERERDALGLRGLLPPRVFTLEQQ 63
>UniRef50_Q0AIF8 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=2;
Nitrosomonas|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Nitrosomonas
eutropha (strain C71)
Length = 536
Score = 118 bits (284), Expect = 1e-25
Identities = 62/142 (43%), Positives = 83/142 (58%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
+YIYL LL+RN+ LFYR + D++ E+MP+VYTPTVG AC K ++R+P+G +IT D+
Sbjct: 62 KYIYLNDLLERNQQLFYRTLVDHIGEIMPLVYTPTVGEACVKLSHIFRKPQGFYITPEDR 121
Query: 434 GHVYDVLKNWPETDVRAIVVTDGERFWVWATWAHAGWASLWANSRSTPRSEASSRISVCP 613
G + LKNWPETDV+ IVVTDGER G L AN P + S ++ C
Sbjct: 122 GEIISRLKNWPETDVQIIVVTDGERI--------LGLGDLGANGMGIPIGKISLYVA-CA 172
Query: 614 SLSTWVRTPSRCWTTRCTSGSG 679
+ P RC G+G
Sbjct: 173 GI-----YPDRCMPVMLDVGTG 189
Score = 82.2 bits (194), Expect = 1e-14
Identities = 33/54 (61%), Positives = 44/54 (81%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 672
LGLGDLGA GMGIP+GK++LY A GI P +C+P+ +DVGT Q++ +DPLY+G
Sbjct: 148 LGLGDLGANGMGIPIGKISLYVACAGIYPDRCMPVMLDVGTGNQALREDPLYLG 201
>UniRef50_Q89G76 Cluster: Malic enzyme; n=3; cellular organisms|Rep:
Malic enzyme - Bradyrhizobium japonicum
Length = 531
Score = 118 bits (283), Expect = 2e-25
Identities = 51/85 (60%), Positives = 67/85 (78%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
+Y+ L L DRNE LF+R V DN+ E+ PI+YTPTVGLACQK+GL+++RPRG+FI+ D+
Sbjct: 56 KYVALNALHDRNEALFFRVVVDNIDEIQPIIYTPTVGLACQKYGLIFQRPRGMFISSRDR 115
Query: 434 GHVYDVLKNWPETDVRAIVVTDGER 508
G + ++LKNWP R IVVTDGER
Sbjct: 116 GQIAEILKNWP-YPARLIVVTDGER 139
Score = 89.8 bits (213), Expect = 5e-17
Identities = 38/56 (67%), Positives = 46/56 (82%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LGLGDLGA GMGIPVGKL+LY+A G+ P CLPI +DVGTN + +L+DP Y+GLR
Sbjct: 141 LGLGDLGANGMGIPVGKLSLYSACAGVHPEHCLPIVLDVGTNNEELLNDPYYLGLR 196
>UniRef50_P16243 Cluster: NADP-dependent malic enzyme, chloroplast
precursor; n=79; Magnoliophyta|Rep: NADP-dependent malic
enzyme, chloroplast precursor - Zea mays (Maize)
Length = 636
Score = 113 bits (273), Expect = 3e-24
Identities = 47/93 (50%), Positives = 69/93 (74%)
Frame = +2
Query: 230 RQIRKST*QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRG 409
RQ + +YI +M L + +E LFY+ + DNV E++P VYTPTVG ACQK+G ++ RP+G
Sbjct: 145 RQYQTPLQRYIAMMNLQETDERLFYKLLIDNVVELLPFVYTPTVGEACQKYGSIFGRPQG 204
Query: 410 LFITIHDKGHVYDVLKNWPETDVRAIVVTDGER 508
L++++ DKG V +VL+NWP +++ I VTDGER
Sbjct: 205 LYVSLKDKGKVLEVLRNWPHRNIQVICVTDGER 237
Score = 95.5 bits (227), Expect = 1e-18
Identities = 44/64 (68%), Positives = 48/64 (75%)
Frame = +1
Query: 487 CCNRRRTFLGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLY 666
C LGLGDLG GMGIPVGKLALYTALGG+ P CLPITIDVGTN + +L+D Y
Sbjct: 231 CVTDGERILGLGDLGCQGMGIPVGKLALYTALGGVDPSVCLPITIDVGTNNEFLLNDEFY 290
Query: 667 IGLR 678
IGLR
Sbjct: 291 IGLR 294
>UniRef50_A7PC00 Cluster: Chromosome chr2 scaffold_11, whole genome
shotgun sequence; n=3; Vitis vinifera|Rep: Chromosome
chr2 scaffold_11, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 573
Score = 110 bits (264), Expect = 4e-23
Identities = 47/93 (50%), Positives = 67/93 (72%)
Frame = +2
Query: 230 RQIRKST*QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRG 409
RQ + +Y+ +M +RNE LFY+ + DNV E++P+VYTPTVG ACQK+G ++RRP+
Sbjct: 245 RQYKVPLQRYMAMMDFQERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFRRPQS 304
Query: 410 LFITIHDKGHVYDVLKNWPETDVRAIVVTDGER 508
L+I G + +VLKNWPE ++ IVVT+GER
Sbjct: 305 LYIIDFFMGKILEVLKNWPERSIQVIVVTNGER 337
Score = 89.4 bits (212), Expect = 7e-17
Identities = 39/56 (69%), Positives = 45/56 (80%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LGLGDLG GMGIPVGKL+LYT LGG+ P CLP+TIDVGTN + +L D YIGL+
Sbjct: 339 LGLGDLGCQGMGIPVGKLSLYTTLGGLHPSVCLPVTIDVGTNNEQLLKDEFYIGLK 394
>UniRef50_Q016K2 Cluster: NADP dependent malic enzyme; n=2;
Ostreococcus|Rep: NADP dependent malic enzyme -
Ostreococcus tauri
Length = 641
Score = 105 bits (253), Expect = 8e-22
Identities = 43/93 (46%), Positives = 69/93 (74%)
Frame = +2
Query: 230 RQIRKST*QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRG 409
R++ ++ +L L +RNE LFYR V D++ E++P++ PTV C++ GL+YR+PRG
Sbjct: 131 RRVTSGVEKHAWLPALYERNERLFYRVVKDHLEELLPVLAEPTVWQVCREAGLMYRQPRG 190
Query: 410 LFITIHDKGHVYDVLKNWPETDVRAIVVTDGER 508
L++++ DKG VY +LKNWP +V+A+V+TDG+R
Sbjct: 191 LYVSMQDKGSVYRLLKNWPVRNVKAVVLTDGQR 223
Score = 70.5 bits (165), Expect = 3e-11
Identities = 32/55 (58%), Positives = 40/55 (72%)
Frame = +1
Query: 514 GLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
G+GDLG GM V K +L+TALGG+ P LPI IDVGT+ Q++L+D YIGLR
Sbjct: 226 GIGDLGVQGMPAAVSKASLFTALGGLDPADVLPICIDVGTDNQTLLEDKFYIGLR 280
>UniRef50_Q8D911 Cluster: NAD-dependent malic enzyme; n=187;
cellular organisms|Rep: NAD-dependent malic enzyme -
Vibrio vulnificus
Length = 562
Score = 101 bits (242), Expect = 2e-20
Identities = 44/85 (51%), Positives = 61/85 (71%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
++IYL + D NE LFYR V +++ EMMPI+YTPTVG AC+ F +YRR RGLF++ ++
Sbjct: 70 KHIYLRNIQDTNETLFYRLVQNHITEMMPIIYTPTVGAACENFSNIYRRGRGLFVSYANR 129
Query: 434 GHVYDVLKNWPETDVRAIVVTDGER 508
+ D+L N +V+ IVVTDGER
Sbjct: 130 DRIDDILNNASNHNVKVIVVTDGER 154
Score = 79.4 bits (187), Expect = 7e-14
Identities = 36/56 (64%), Positives = 41/56 (73%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LGLGD G GMGIP+GKL+LYTA GGI P LPI +DVGTN L DP+Y+G R
Sbjct: 156 LGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPIVLDVGTNNPQRLADPMYMGWR 211
>UniRef50_A6SA55 Cluster: Malic enzyme; n=2; Sclerotiniaceae|Rep:
Malic enzyme - Botryotinia fuckeliana B05.10
Length = 685
Score = 100 bits (239), Expect = 4e-20
Identities = 39/85 (45%), Positives = 63/85 (74%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
+Y+YL L + N HLFYR V +++ ++ P++YTPTVG AC ++ +Y++P GL+++ HD+
Sbjct: 146 KYMYLSNLRNNNVHLFYRLVQEHLTDITPLIYTPTVGEACLRWSEIYQQPEGLYLSYHDR 205
Query: 434 GHVYDVLKNWPETDVRAIVVTDGER 508
G++ +VL NW ++DV VVTDG R
Sbjct: 206 GNLEEVLGNWRQSDVEMTVVTDGSR 230
Score = 82.6 bits (195), Expect = 8e-15
Identities = 37/56 (66%), Positives = 43/56 (76%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LGLGDLG GMGIPVGKL+LYT GI P + LPIT+D+GTN + L DPLY+G R
Sbjct: 232 LGLGDLGVNGMGIPVGKLSLYTGCAGIHPSKTLPITLDLGTNNEKFLKDPLYMGNR 287
>UniRef50_A7IMB8 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=2;
Alphaproteobacteria|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Xanthobacter
sp. (strain Py2)
Length = 550
Score = 97.9 bits (233), Expect = 2e-19
Identities = 43/85 (50%), Positives = 59/85 (69%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
QY YLM L RNE +FY+ V + +PI+Y PTV AC+ FG +YRRPRG++IT H K
Sbjct: 75 QYSYLMDLEARNETVFYKAVMSDPKRFIPILYDPTVADACEAFGNLYRRPRGMYITRHMK 134
Query: 434 GHVYDVLKNWPETDVRAIVVTDGER 508
G + +VL+NWP+ D+R + V+ G R
Sbjct: 135 GRMAEVLRNWPQKDIRFVCVSTGGR 159
Score = 73.3 bits (172), Expect = 5e-12
Identities = 31/64 (48%), Positives = 41/64 (64%)
Frame = +1
Query: 487 CCNRRRTFLGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLY 666
C + LGLGD+GA GMGIP+GKL LYTA + P LP+ D+GT+ + + DP Y
Sbjct: 153 CVSTGGRILGLGDIGANGMGIPIGKLQLYTACAAVPPDVLLPVLFDIGTSNEHLRADPFY 212
Query: 667 IGLR 678
+G R
Sbjct: 213 LGTR 216
Score = 34.7 bits (76), Expect = 2.1
Identities = 17/38 (44%), Positives = 22/38 (57%)
Frame = +1
Query: 70 PTSGLSGLDHLKHPGLNKGMAFTIEERQSWGSTGCYHH 183
P S LSGL+ L P NKG A+T ++R+ G G H
Sbjct: 13 PKSNLSGLNLLHDPVRNKGTAYTRDDRRQLGLEGLLPH 50
>UniRef50_Q8I8I4 Cluster: Malic enzyme; n=4; Eukaryota|Rep: Malic
enzyme - Mastigamoeba balamuthi (Phreatamoeba balamuthi)
Length = 568
Score = 97.9 bits (233), Expect = 2e-19
Identities = 45/85 (52%), Positives = 58/85 (68%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
+Y+YL L RN+ LF+ V +V E +P+VYTPTVG C KF +R P GL+IT DK
Sbjct: 91 KYLYLSQLSQRNQTLFFYLVQHHVEECVPLVYTPTVGEGCTKFSAEFRNPTGLYITPEDK 150
Query: 434 GHVYDVLKNWPETDVRAIVVTDGER 508
GHV ++L+NWP +V IVVTDG R
Sbjct: 151 GHVAEILENWPH-EVEIIVVTDGGR 174
Score = 85.0 bits (201), Expect = 2e-15
Identities = 36/56 (64%), Positives = 45/56 (80%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LGLGDLG+ GMGIP+GKL LY A G +P + LP+ IDVGTN Q +LDDP+Y+G+R
Sbjct: 176 LGLGDLGSNGMGIPIGKLHLYIACAGFRPDRTLPVMIDVGTNRQELLDDPMYLGVR 231
>UniRef50_Q86NT5 Cluster: Malic enzyme; n=2; Drosophila
melanogaster|Rep: Malic enzyme - Drosophila melanogaster
(Fruit fly)
Length = 610
Score = 97.5 bits (232), Expect = 3e-19
Identities = 43/86 (50%), Positives = 60/86 (69%), Gaps = 1/86 (1%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
+Y YL L E L+++FV+ NV ++PI+YTPTVGLAC +G++YR G+ IT HD+
Sbjct: 102 RYRYLRALRQGYERLYFQFVSKNVHAVLPIIYTPTVGLACTVYGMLYRGMTGIHITKHDR 161
Query: 434 GHVYDVLKNWP-ETDVRAIVVTDGER 508
GH+ +L NWP V+AI VTDG+R
Sbjct: 162 GHMKQILSNWPMRRSVKAICVTDGQR 187
Score = 87.4 bits (207), Expect = 3e-16
Identities = 41/64 (64%), Positives = 47/64 (73%)
Frame = +1
Query: 487 CCNRRRTFLGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLY 666
C + LGLGDLGA GMGI VGK+ LYTAL GI P LPI +DVGTN +S+ +DPLY
Sbjct: 181 CVTDGQRILGLGDLGANGMGIAVGKMELYTALAGIPPSMLLPICLDVGTNNKSLHEDPLY 240
Query: 667 IGLR 678
IGLR
Sbjct: 241 IGLR 244
>UniRef50_UPI0000D9F768 Cluster: PREDICTED: similar to Y48B6A.12,
partial; n=1; Macaca mulatta|Rep: PREDICTED: similar to
Y48B6A.12, partial - Macaca mulatta
Length = 456
Score = 95.9 bits (228), Expect = 8e-19
Identities = 44/85 (51%), Positives = 59/85 (69%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
+YIYL L DRNE L+++ + D+VAEMMPIVYTP VG ACQ FG ++R RGL+ + +K
Sbjct: 63 KYIYLESLHDRNETLYFKLLVDHVAEMMPIVYTPVVGKACQLFGHIFRNARGLYFNLSEK 122
Query: 434 GHVYDVLKNWPETDVRAIVVTDGER 508
G+ +++ N D IVVTDG R
Sbjct: 123 GNFKEMVWNSNVRDADIIVVTDGSR 147
Score = 78.2 bits (184), Expect = 2e-13
Identities = 33/56 (58%), Positives = 43/56 (76%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LGLGDLG GMGIP+GKL+LY A GI P + +P+T+DVGTN +L+D +Y+G R
Sbjct: 149 LGLGDLGTNGMGIPIGKLSLYVACAGINPGRTVPVTLDVGTNNPDLLNDDMYLGER 204
>UniRef50_A3QW96 Cluster: Malic enzyme; n=10; Tigriopus
californicus|Rep: Malic enzyme - Tigriopus californicus
(Marine copepod)
Length = 322
Score = 95.9 bits (228), Expect = 8e-19
Identities = 40/81 (49%), Positives = 55/81 (67%)
Frame = +2
Query: 266 LMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVY 445
L + DRNE LFYR + DN +M PI+YTPTVG AC F +YRRPRG++ + D+G +
Sbjct: 124 LQSVQDRNETLFYRILMDNFQDMAPIIYTPTVGWACSHFSQLYRRPRGMYFSHGDRGEMA 183
Query: 446 DVLKNWPETDVRAIVVTDGER 508
++ NW +V A+V+TDG R
Sbjct: 184 SMVYNWESDEVDAVVITDGSR 204
Score = 77.4 bits (182), Expect = 3e-13
Identities = 32/56 (57%), Positives = 42/56 (75%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LGLGDLG G+GI +GKL LY A GG P + LP+ +D+GTN Q +L+DP Y+GL+
Sbjct: 206 LGLGDLGLGGLGISIGKLDLYVAAGGFHPRRVLPVVLDIGTNNQKLLNDPNYLGLK 261
>UniRef50_P37221 Cluster: NAD-dependent malic enzyme 62 kDa isoform,
mitochondrial precursor; n=41; Eukaryota|Rep:
NAD-dependent malic enzyme 62 kDa isoform, mitochondrial
precursor - Solanum tuberosum (Potato)
Length = 626
Score = 95.9 bits (228), Expect = 8e-19
Identities = 40/78 (51%), Positives = 55/78 (70%)
Frame = +2
Query: 275 LLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVL 454
L DRNE L+Y+ + +N+ E PIVYTPTVGL CQK+ ++RRPRG++ + D+G + ++
Sbjct: 122 LHDRNETLYYKVLMENIEEYAPIVYTPTVGLVCQKYSGLFRRPRGMYFSAEDRGEMMSMV 181
Query: 455 KNWPETDVRAIVVTDGER 508
NWP V IVVTDG R
Sbjct: 182 YNWPADQVDMIVVTDGSR 199
Score = 76.2 bits (179), Expect = 7e-13
Identities = 33/56 (58%), Positives = 43/56 (76%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LGLGDLG G+GI +GKL LY A GI P + LP+ IDVGT+ +++L DPLY+GL+
Sbjct: 201 LGLGDLGIQGIGIAIGKLDLYVAAAGINPQRVLPVMIDVGTDNENLLKDPLYLGLQ 256
>UniRef50_Q4X1Z2 Cluster: NADP-dependent malic enzyme MaeA; n=11;
Pezizomycotina|Rep: NADP-dependent malic enzyme MaeA -
Aspergillus fumigatus (Sartorya fumigata)
Length = 661
Score = 94.3 bits (224), Expect = 2e-18
Identities = 36/85 (42%), Positives = 59/85 (69%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
+++YL L N HLFYR V D++ E+ P++YTP VG ACQK+ +Y++P G++++ D+
Sbjct: 138 KFLYLSTLRKNNVHLFYRLVTDHLKELTPLIYTPVVGEACQKWSEIYQQPEGMYLSWEDR 197
Query: 434 GHVYDVLKNWPETDVRAIVVTDGER 508
G++ V+ NWP+ +V +TDG R
Sbjct: 198 GNLAAVIANWPQPNVEITCITDGSR 222
Score = 83.8 bits (198), Expect = 3e-15
Identities = 36/64 (56%), Positives = 47/64 (73%)
Frame = +1
Query: 487 CCNRRRTFLGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLY 666
C LGLGDLG GMGIP+GKLALYTA GI+P LP+T+D+GT+ +++ +DPLY
Sbjct: 216 CITDGSRILGLGDLGINGMGIPIGKLALYTACAGIRPEATLPLTLDLGTSNKALREDPLY 275
Query: 667 IGLR 678
+G R
Sbjct: 276 MGTR 279
>UniRef50_P78715 Cluster: Malic enzyme, hydrogenosomal precursor;
n=1; Neocallimastix frontalis|Rep: Malic enzyme,
hydrogenosomal precursor - Neocallimastix frontalis
(Rumen fungus)
Length = 592
Score = 93.9 bits (223), Expect = 3e-18
Identities = 40/85 (47%), Positives = 57/85 (67%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
++IYL L +RNE L+Y+ + +N E+ PI+YTP VG ACQKF ++ + RG++ + D+
Sbjct: 103 KFIYLNHLQNRNETLYYKMILENFVELAPIIYTPVVGEACQKFHKIFTQTRGMYFSTADR 162
Query: 434 GHVYDVLKNWPETDVRAIVVTDGER 508
G + V NWP DV IVVTDG R
Sbjct: 163 GQMSAVAANWPYDDVDVIVVTDGSR 187
Score = 81.0 bits (191), Expect = 2e-14
Identities = 35/56 (62%), Positives = 43/56 (76%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LGLGDLGA GM IP+GKL LY GGI P LPI +DVGTN + +L+DPLY+G++
Sbjct: 189 LGLGDLGAGGMQIPIGKLTLYVCGGGINPRNVLPIVLDVGTNNKELLNDPLYLGMQ 244
Score = 37.9 bits (84), Expect = 0.23
Identities = 15/32 (46%), Positives = 23/32 (71%)
Frame = +3
Query: 156 LGIHGLLPPRVKTQEEQVELCKLSIDRYENPL 251
LGI GL+PPR ++ E Q + CK ++D+ +PL
Sbjct: 70 LGIRGLVPPRPQSLEAQYKRCKTNLDKISDPL 101
Score = 32.7 bits (71), Expect = 8.5
Identities = 15/29 (51%), Positives = 18/29 (62%)
Frame = +1
Query: 85 SGLDHLKHPGLNKGMAFTIEERQSWGSTG 171
+GLD L P LNKG AFT +E+ G G
Sbjct: 46 TGLDILNDPKLNKGSAFTADEKDRLGIRG 74
>UniRef50_A1ZAF7 Cluster: Malic enzyme; n=5; Sophophora|Rep: Malic
enzyme - Drosophila melanogaster (Fruit fly)
Length = 603
Score = 93.1 bits (221), Expect = 6e-18
Identities = 39/85 (45%), Positives = 59/85 (69%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
++ YL + R+ L+YRF+ +N+ + +PIVYTPTVG +GL +++ LFI+IHDK
Sbjct: 94 RFTYLSAVHHRHRRLYYRFIKENIEKSLPIVYTPTVGDVVATYGLNFQQAISLFISIHDK 153
Query: 434 GHVYDVLKNWPETDVRAIVVTDGER 508
GH+ D++ NW + V+AI VTDG R
Sbjct: 154 GHIRDLMHNWVDEGVKAICVTDGGR 178
Score = 77.8 bits (183), Expect = 2e-13
Identities = 33/56 (58%), Positives = 43/56 (76%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LGLGD+GA MGI +GK+ LYTALG I P +P+ +DVGT+ Q++L DPLY+G R
Sbjct: 180 LGLGDMGANAMGISLGKMILYTALGSIPPSTLMPVCLDVGTDNQALLQDPLYVGAR 235
>UniRef50_Q01AM5 Cluster: NADP+-dependent malic enzyme; n=2;
Ostreococcus|Rep: NADP+-dependent malic enzyme -
Ostreococcus tauri
Length = 580
Score = 91.9 bits (218), Expect = 1e-17
Identities = 39/85 (45%), Positives = 58/85 (68%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
+Y L+ L +E FYR + ++PI+YTPTVG AC KFG + +RP GL+++ +D
Sbjct: 102 KYKQLVALQMTDESTFYRMLRSQTETLLPILYTPTVGEACVKFGTLVQRPMGLWVSSNDA 161
Query: 434 GHVYDVLKNWPETDVRAIVVTDGER 508
G+V +++NWP TDV+ V+TDGER
Sbjct: 162 GNVKQLIRNWPATDVKIAVITDGER 186
Score = 72.1 bits (169), Expect = 1e-11
Identities = 34/56 (60%), Positives = 40/56 (71%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LGLGD GA GMGI GK +Y A G + P LPI +D GTN Q++LDDPLYIGL+
Sbjct: 188 LGLGDQGANGMGISAGKSMVYAACG-VPPSALLPIQVDTGTNNQTLLDDPLYIGLK 242
>UniRef50_Q00XN9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus tauri
Length = 639
Score = 89.8 bits (213), Expect = 5e-17
Identities = 44/97 (45%), Positives = 63/97 (64%)
Frame = +2
Query: 218 QALDRQIRKST*QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYR 397
Q+L+R + K + +L L DRNE LFYR V D++ E+ PI+YTPTVG AC F + R
Sbjct: 129 QSLERPLDK----WQHLQDLKDRNETLFYRLVHDHIEELAPIIYTPTVGDACLNFSKLLR 184
Query: 398 RPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGER 508
R RG++ ++ D+G + ++ NW + V IVVTDG R
Sbjct: 185 RARGMYFSVDDRGDINSMMFNW-KRSVSVIVVTDGSR 220
Score = 72.1 bits (169), Expect = 1e-11
Identities = 31/55 (56%), Positives = 39/55 (70%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 675
LGLGDLG GMGI GK+ LY A GG P LP+ +DVGTN + +L+DP Y+G+
Sbjct: 222 LGLGDLGTNGMGISQGKVDLYVAGGGFDPQHVLPVVLDVGTNNEDLLNDPYYLGV 276
>UniRef50_A3BK03 Cluster: Malic enzyme; n=2; Oryza sativa|Rep: Malic
enzyme - Oryza sativa subsp. japonica (Rice)
Length = 635
Score = 89.0 bits (211), Expect = 9e-17
Identities = 39/80 (48%), Positives = 54/80 (67%), Gaps = 2/80 (2%)
Frame = +2
Query: 275 LLDRNEHLFYR--FVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYD 448
L DRNE ++Y+ + DN+ E PIVYTPTVGL CQ + ++RRPRG++ + D+G +
Sbjct: 154 LHDRNETMYYKAEVLIDNIEEHAPIVYTPTVGLVCQNYSGLFRRPRGMYFSAEDRGEMMS 213
Query: 449 VLKNWPETDVRAIVVTDGER 508
++ NWP V IVVTDG R
Sbjct: 214 MVYNWPADQVDMIVVTDGSR 233
Score = 78.2 bits (184), Expect = 2e-13
Identities = 34/56 (60%), Positives = 42/56 (75%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LGLGDLG G+GI +GKL LY A GI P + LP+ IDVGTN + +L DPLY+GL+
Sbjct: 235 LGLGDLGVHGIGIAIGKLDLYVAAAGINPQRVLPVMIDVGTNNEKLLKDPLYLGLQ 290
>UniRef50_Q875H8 Cluster: Malic enzyme; n=1; Mucor
circinelloides|Rep: Malic enzyme - Mucor circinelloides
Length = 617
Score = 87.8 bits (208), Expect = 2e-16
Identities = 37/85 (43%), Positives = 57/85 (67%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
++++L L DRNE L+Y+ + +++ E+ I+YTPTVGLA Q +YRR RG++ + D+
Sbjct: 106 KFVFLAALHDRNETLYYKIIMEHLEELAGIIYTPTVGLASQMSHSIYRRSRGMYFSSQDR 165
Query: 434 GHVYDVLKNWPETDVRAIVVTDGER 508
G + ++ NWP V IVVTDG R
Sbjct: 166 GQMSAMVYNWPHDKVDVIVVTDGSR 190
Score = 85.4 bits (202), Expect = 1e-15
Identities = 36/55 (65%), Positives = 45/55 (81%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 675
LGLGDLGA GM IP+GKL+LY A GGI+P LP+ +DVGTN Q +L+DPLY+G+
Sbjct: 192 LGLGDLGANGMEIPIGKLSLYVAAGGIRPRAVLPVVLDVGTNNQDLLNDPLYLGM 246
>UniRef50_Q4PC56 Cluster: Malic enzyme; n=1; Ustilago maydis|Rep:
Malic enzyme - Ustilago maydis (Smut fungus)
Length = 634
Score = 87.4 bits (207), Expect = 3e-16
Identities = 38/87 (43%), Positives = 55/87 (63%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
+++ L L N L+Y + N E++P++YTPTVG ACQKF +YRRP GL I++ DK
Sbjct: 133 KHVMLASLRQTNTRLYYATILANKEEILPLIYTPTVGEACQKFSHIYRRPEGLSISLEDK 192
Query: 434 GHVYDVLKNW--PETDVRAIVVTDGER 508
G + +++NW P R V+TDG R
Sbjct: 193 GKIASIVENWPVPAGSPRIAVITDGSR 219
Score = 75.4 bits (177), Expect = 1e-12
Identities = 34/56 (60%), Positives = 41/56 (73%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LGLGDLG G GI +GKL+LY A GI P LPI +D+GTN + L+DPLY+GLR
Sbjct: 221 LGLGDLGWNGQGISIGKLSLYVAGAGIHPRATLPIVVDLGTNNKKNLEDPLYLGLR 276
>UniRef50_Q9HE50 Cluster: Malic enzyme; n=6; Pezizomycotina|Rep:
Malic enzyme - Neurospora crassa
Length = 1023
Score = 87.0 bits (206), Expect = 4e-16
Identities = 36/85 (42%), Positives = 53/85 (62%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
+Y+YL + +N LFYR + D+ EMMP+VYTPT+G C ++ +Y RP L+I+I +
Sbjct: 528 RYLYLSTIKSQNVDLFYRLLMDHAKEMMPLVYTPTIGDVCLQYSTLYTRPEALYISIKQR 587
Query: 434 GHVYDVLKNWPETDVRAIVVTDGER 508
+ +L+NWP VVTDG R
Sbjct: 588 KSIRTILRNWPYPQPEICVVTDGSR 612
Score = 80.2 bits (189), Expect = 4e-14
Identities = 36/56 (64%), Positives = 43/56 (76%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LGLGDLG G+GIP+GKLALYTA GI P + LPI +D GT ++ L DPLY+GLR
Sbjct: 614 LGLGDLGVNGVGIPIGKLALYTAAAGIHPDKTLPIVLDCGTANETNLKDPLYLGLR 669
>UniRef50_A0Q531 Cluster: NAD-dependent malic enzyme; n=10;
Francisella tularensis|Rep: NAD-dependent malic enzyme -
Francisella tularensis subsp. novicida (strain U112)
Length = 604
Score = 85.4 bits (202), Expect = 1e-15
Identities = 38/84 (45%), Positives = 56/84 (66%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
+Y++L L D N LFY FV +N+ E+MPI+YTPTVG A QK+ +R+ GLFI+I K
Sbjct: 83 KYVFLNRLHDLNTTLFYHFVRENLEEIMPIIYTPTVGEAVQKYSSSFRKQSGLFISISHK 142
Query: 434 GHVYDVLKNWPETDVRAIVVTDGE 505
H+ +L+ + + ++VTDGE
Sbjct: 143 KHIARILERYEYNSIDLVLVTDGE 166
Score = 63.3 bits (147), Expect = 5e-09
Identities = 26/56 (46%), Positives = 39/56 (69%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LG+GD G GM I +GK+ +Y A GI P + LP+ +D+GTN ++L+ P Y+G+R
Sbjct: 169 LGIGDQGIGGMNISIGKIMVYVAASGIDPARVLPVQLDMGTNNDALLNAPGYLGVR 224
>UniRef50_A4RQC9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus lucimarinus CCE9901
Length = 549
Score = 85.0 bits (201), Expect = 2e-15
Identities = 39/85 (45%), Positives = 55/85 (64%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
+YI+L L +NE LFYR + +++ ++MPIVYTPTVG AC F +YR G++ + D
Sbjct: 65 RYIFLENLHMQNERLFYRVLVEHLEDLMPIVYTPTVGEACINFDALYRNRCGMYFSRLDS 124
Query: 434 GHVYDVLKNWPETDVRAIVVTDGER 508
G + +L NWP + IVVTDG R
Sbjct: 125 GVMRRMLDNWPSPETEIIVVTDGGR 149
Score = 58.4 bits (135), Expect = 1e-07
Identities = 25/54 (46%), Positives = 36/54 (66%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 672
LGLGDLG GM I VGK++LY A GG P + +P+ +D+GT+ ++ Y+G
Sbjct: 151 LGLGDLGTNGMAISVGKVSLYVASGGFDPAKSMPVCLDLGTSNVALRAHDFYLG 204
>UniRef50_Q5K758 Cluster: Malic enzyme; n=1; Filobasidiella
neoformans|Rep: Malic enzyme - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 600
Score = 84.6 bits (200), Expect = 2e-15
Identities = 36/56 (64%), Positives = 45/56 (80%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LGLGDLG GMGI VGKL LY A GG+ PH CLP+ +D+GTN +++ +DPLYIGL+
Sbjct: 196 LGLGDLGIGGMGISVGKLNLYVAGGGVNPHGCLPVVLDMGTNNEAVRNDPLYIGLK 251
Score = 72.5 bits (170), Expect = 9e-12
Identities = 33/88 (37%), Positives = 54/88 (61%), Gaps = 3/88 (3%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
++++L + + +LF+ + D + E+ PIVYTPTVG ACQK+ +Y P GL++ I DK
Sbjct: 107 KHVHLSKIRREDPNLFFSVMRDELTELAPIVYTPTVGEACQKYSQIYSGPEGLYLNIEDK 166
Query: 434 GHVYDVLKNWPETDV---RAIVVTDGER 508
+ ++L + V + +VVTDG R
Sbjct: 167 DRIPEILHQYASKLVAPPQILVVTDGSR 194
>UniRef50_Q9RYN4 Cluster: Malate oxidoreductase; n=6;
Deinococci|Rep: Malate oxidoreductase - Deinococcus
radiodurans
Length = 580
Score = 83.8 bits (198), Expect = 3e-15
Identities = 41/82 (50%), Positives = 52/82 (63%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
+++YL L DRNE LFY ++ +V EM+PIVYTPTVG A +KF +YR PRGL ++
Sbjct: 93 KHVYLRNLQDRNEVLFYALLSHHVEEMLPIVYTPTVGDAVKKFSQIYRYPRGLTLSTRTI 152
Query: 434 GHVYDVLKNWPETDVRAIVVTD 499
L N P DVR IV TD
Sbjct: 153 ERAEQALANVPLNDVRIIVATD 174
Score = 66.1 bits (154), Expect = 7e-10
Identities = 27/56 (48%), Positives = 39/56 (69%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LG+GD G GM I +GKL+LYT GG+ P + LP+ +DVGT + +DP Y+G++
Sbjct: 179 LGIGDQGFGGMAISIGKLSLYTVAGGVGPDKTLPVELDVGTGRADLREDPHYLGVK 234
>UniRef50_A2EKE3 Cluster: Malic enzyme; n=14; Trichomonadidae|Rep:
Malic enzyme - Trichomonas vaginalis G3
Length = 567
Score = 82.6 bits (195), Expect = 8e-15
Identities = 39/86 (45%), Positives = 56/86 (65%), Gaps = 1/86 (1%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAE-MMPIVYTPTVGLACQKFGLVYRRPRGLFITIHD 430
+YI+L ++N F+RF+ + E MPI+YTPTVG ACQK+ + RG++IT D
Sbjct: 80 KYIFLANEREKNSQSFWRFLFTHPPEETMPILYTPTVGEACQKWATHRQSYRGIYITPED 139
Query: 431 KGHVYDVLKNWPETDVRAIVVTDGER 508
G + D+L+N+P D+R IVVTD R
Sbjct: 140 SGKIKDILRNYPRQDIRCIVVTDAGR 165
Score = 77.4 bits (182), Expect = 3e-13
Identities = 34/56 (60%), Positives = 43/56 (76%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LGLGDLGA G+GIPVGKL LYT +G + P Q LP+ +D+GT+ + +L DPLY G R
Sbjct: 167 LGLGDLGASGLGIPVGKLMLYTLIGQVDPDQTLPVQLDMGTDRKEILADPLYHGWR 222
>UniRef50_A4RZU1 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus lucimarinus CCE9901
Length = 539
Score = 82.2 bits (194), Expect = 1e-14
Identities = 36/56 (64%), Positives = 42/56 (75%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LGLGDLGA GMGI GK+ LYT G++P CLP+ +DVGTN Q +LDDP Y GLR
Sbjct: 136 LGLGDLGAGGMGISEGKILLYTVCAGVRPSACLPVCLDVGTNNQRLLDDPNYKGLR 191
Score = 55.6 bits (128), Expect = 1e-06
Identities = 26/63 (41%), Positives = 36/63 (57%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
+Y+YL L + FYR + E+MP VYTPTVG AC+K+ + G++IT D
Sbjct: 20 RYVYLRELQRASAETFYRALVREPLELMPFVYTPTVGEACEKYHRLGIETNGVYITADDA 79
Query: 434 GHV 442
G V
Sbjct: 80 GRV 82
>UniRef50_A1SVL3 Cluster: Malic enzyme aka malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=4;
Gammaproteobacteria|Rep: Malic enzyme aka malate
dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)) -
Psychromonas ingrahamii (strain 37)
Length = 571
Score = 80.2 bits (189), Expect = 4e-14
Identities = 37/84 (44%), Positives = 54/84 (64%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
+Y YL L DRNE LFY ++ N+ EM PI+YTPTVG ACQ+F ++ RGL++T +
Sbjct: 80 KYQYLRALQDRNETLFYALISRNIEEMTPIIYTPTVGKACQEFSHRFQIARGLYLTTDNI 139
Query: 434 GHVYDVLKNWPETDVRAIVVTDGE 505
V + + + D++ IVVTD +
Sbjct: 140 HDVGSMAREFTGKDIQIIVVTDSQ 163
Score = 78.2 bits (184), Expect = 2e-13
Identities = 31/55 (56%), Positives = 42/55 (76%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 675
LG+GD G GMGIP+GKL+LYT GI P C+PI +D+GT+ Q +L DP+Y+G+
Sbjct: 166 LGIGDQGVGGMGIPIGKLSLYTLGAGIHPDHCMPIALDIGTDNQDLLADPMYLGI 220
>UniRef50_A5C6I9 Cluster: Malic enzyme; n=1; Vitis vinifera|Rep:
Malic enzyme - Vitis vinifera (Grape)
Length = 498
Score = 80.2 bits (189), Expect = 4e-14
Identities = 35/56 (62%), Positives = 43/56 (76%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LGLGDLG G+GIP+GKL +Y A GI P + LPI +DVGTN Q +L+D LY+GLR
Sbjct: 53 LGLGDLGVQGIGIPIGKLDMYVAAAGINPQRILPIMLDVGTNNQRLLEDRLYLGLR 108
>UniRef50_P45868 Cluster: Probable NAD-dependent malic enzyme 2;
n=37; Bacteria|Rep: Probable NAD-dependent malic enzyme
2 - Bacillus subtilis
Length = 582
Score = 80.2 bits (189), Expect = 4e-14
Identities = 46/128 (35%), Positives = 70/128 (54%), Gaps = 2/128 (1%)
Frame = +2
Query: 164 PRVVTTTSQDARGAG*TMQALDRQIRKST*QYIYLMGLLDRNEHLFYRFVADNVAEMMPI 343
P V + Q A+ A QA ++R Q +YL L +RNE LFY+ + +++ EM+P+
Sbjct: 65 PPTVLSLDQQAQRAYEQFQAQPDRLR----QNVYLSDLANRNEVLFYKLLKNHLREMLPV 120
Query: 344 VYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPET--DVRAIVVTDGERFWV 517
VYTPTVG A Q++ YRRP+G++++I + + +N T D+ IV TD E
Sbjct: 121 VYTPTVGEAIQEYSHEYRRPQGIYLSIDNIDGIEKAFENLHATAGDIDLIVATDSESILG 180
Query: 518 WATWAHAG 541
W G
Sbjct: 181 IGDWGVGG 188
Score = 73.7 bits (173), Expect = 4e-12
Identities = 30/56 (53%), Positives = 42/56 (75%)
Frame = +1
Query: 505 TFLGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 672
+ LG+GD G G+ I +GKLA+YTA GI P + +P+ +DVGTN + +L+DPLYIG
Sbjct: 177 SILGIGDWGVGGINIAIGKLAVYTAAAGIDPSRVIPVVLDVGTNNEKLLNDPLYIG 232
Score = 35.1 bits (77), Expect = 1.6
Identities = 17/37 (45%), Positives = 23/37 (62%)
Frame = +1
Query: 61 DGQPTSGLSGLDHLKHPGLNKGMAFTIEERQSWGSTG 171
+G + L G + L P LNKG+AF++EERQ G G
Sbjct: 26 EGHLETTLRGKEVLSIPTLNKGVAFSLEERQELGLEG 62
>UniRef50_Q5CS07 Cluster: Malic enzyme; n=2; Cryptosporidium|Rep:
Malic enzyme - Cryptosporidium parvum Iowa II
Length = 614
Score = 79.4 bits (187), Expect = 7e-14
Identities = 34/55 (61%), Positives = 43/55 (78%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 675
LGLGDLG GMGIP+GKL+LY LGGI P + LPI++D+GTNT +L D Y+G+
Sbjct: 212 LGLGDLGLNGMGIPMGKLSLYITLGGIDPSKVLPISLDIGTNTNDILSDKYYLGI 266
Score = 54.8 bits (126), Expect = 2e-06
Identities = 29/89 (32%), Positives = 48/89 (53%), Gaps = 4/89 (4%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGL--VYRR--PRGLFIT 421
+Y +L + + LF+ + ++ P+VYTPTVG C +F R GL++
Sbjct: 122 KYTFLENIRSSSFILFHSLLDKYFKDLTPLVYTPTVGEGCIEFSRNPTIRNWLGSGLYLN 181
Query: 422 IHDKGHVYDVLKNWPETDVRAIVVTDGER 508
KG +Y++LK++ D+ IV+TDG R
Sbjct: 182 KSHKGRIYEILKDFKSDDIEIIVLTDGGR 210
Score = 36.3 bits (80), Expect = 0.69
Identities = 14/30 (46%), Positives = 23/30 (76%)
Frame = +1
Query: 82 LSGLDHLKHPGLNKGMAFTIEERQSWGSTG 171
L G++ L++P NKG++FT+EER+ +G G
Sbjct: 64 LKGIELLRNPFYNKGLSFTMEERKEYGLEG 93
>UniRef50_A6XP71 Cluster: Malic enzyme protein 2; n=2;
Mucoromycotina|Rep: Malic enzyme protein 2 - Mortierella
alpina (Mortierella renispora)
Length = 669
Score = 78.6 bits (185), Expect = 1e-13
Identities = 36/56 (64%), Positives = 41/56 (73%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LGLGDLG GMGIPVGKL LY A GI P + LPIT+D+GTN + L D Y+GLR
Sbjct: 251 LGLGDLGVGGMGIPVGKLQLYVAGAGIDPRRTLPITLDLGTNNEDKLKDEFYLGLR 306
Score = 68.1 bits (159), Expect = 2e-10
Identities = 34/97 (35%), Positives = 56/97 (57%), Gaps = 12/97 (12%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVY------RRPRGLF 415
+Y++L L + N LFY V D + E +P++YTPTVG ACQ + +Y +P GLF
Sbjct: 153 KYVFLAWLRNTNVRLFYGLVGDQLEETLPLIYTPTVGTACQNYSSIYPFLAPPGQPDGLF 212
Query: 416 ITIHDKGHVYDVLKNW------PETDVRAIVVTDGER 508
++I+D ++ +++N+ P + V+TDG R
Sbjct: 213 LSINDLPNLTQIIQNYKPFPQDPSLTPQIAVITDGSR 249
>UniRef50_Q4QAQ6 Cluster: Malic enzyme, putative; n=20;
Trypanosomatidae|Rep: Malic enzyme, putative -
Leishmania major
Length = 573
Score = 77.0 bits (181), Expect = 4e-13
Identities = 32/56 (57%), Positives = 44/56 (78%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LGLGDLG+ G+GI +GK +LY A GG+KP + LP+ +DVGTN + ++PLY+GLR
Sbjct: 161 LGLGDLGSNGIGISIGKCSLYVAAGGVKPSRVLPVVMDVGTNNLELRNNPLYLGLR 216
Score = 74.1 bits (174), Expect = 3e-12
Identities = 32/85 (37%), Positives = 55/85 (64%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
+Y L + + N L+Y + + + +PIVYTPTVG ACQ++G +Y++ GL++ + K
Sbjct: 75 RYQLLRNVQNTNVTLYYAILTRYLKQTLPIVYTPTVGEACQRYGDLYQKDHGLYLDVASK 134
Query: 434 GHVYDVLKNWPETDVRAIVVTDGER 508
G V +++N +T++ IV+TDG R
Sbjct: 135 GKVRRLIQNLRKTNIDVIVITDGSR 159
Score = 36.7 bits (81), Expect = 0.52
Identities = 17/49 (34%), Positives = 27/49 (55%)
Frame = +3
Query: 123 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNSTSIL 269
G F S + + GLLPP V+T ++QVE ++R+ P+N +L
Sbjct: 31 GTAFTAAERSHMNVEGLLPPSVETLDDQVERYWDQLNRFNEPINRYQLL 79
>UniRef50_Q7SHJ8 Cluster: Malic enzyme; n=12; Pezizomycotina|Rep:
Malic enzyme - Neurospora crassa
Length = 611
Score = 74.9 bits (176), Expect = 2e-12
Identities = 42/109 (38%), Positives = 66/109 (60%), Gaps = 12/109 (11%)
Frame = +2
Query: 215 MQALDRQIRKST*QYI----------YLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVG 364
+Q+L++Q++++ QY ++ + ++NE LFYR + D++ EM +VYTPT G
Sbjct: 68 IQSLEQQVQRAYEQYCSQPNDLAKNTFMTSMKEQNEVLFYRLLHDHLDEMFSVVYTPTEG 127
Query: 365 LACQKFGLVYRRPRGLFITIHDKGHVYDVLKNW--PETDVRAIVVTDGE 505
A Q + ++RRP G+F+ I+D V L W PE D+ IVVTDGE
Sbjct: 128 EAIQNYSRLFRRPEGVFLNINDMDSVKRDLAQWGKPE-DIDYIVVTDGE 175
Score = 64.5 bits (150), Expect = 2e-09
Identities = 28/56 (50%), Positives = 38/56 (67%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LG+GD G G+ I + KL L T GGI P++ LP+ +D GTN + +L D LY+GLR
Sbjct: 178 LGIGDQGCGGILISIAKLVLMTICGGIHPNRVLPVVLDCGTNNEELLKDDLYLGLR 233
>UniRef50_A4SKB8 Cluster: NAD-dependent malic enzyme; n=2;
Aeromonas|Rep: NAD-dependent malic enzyme - Aeromonas
salmonicida (strain A449)
Length = 516
Score = 74.5 bits (175), Expect = 2e-12
Identities = 33/54 (61%), Positives = 41/54 (75%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 672
LGLGDLG GMGI +GKLALY+A GGI P + LP+ +DVGTN +L+D Y+G
Sbjct: 136 LGLGDLGIGGMGICIGKLALYSAAGGINPARTLPLCVDVGTNNPELLEDDSYLG 189
Score = 69.3 bits (162), Expect = 8e-11
Identities = 34/85 (40%), Positives = 53/85 (62%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
Q++ L L + N LFY V ++ E++PI+YTP VG ACQ+ +Y R GL+++ HD+
Sbjct: 51 QHLLLRQLQEDNPVLFYDLVRHHLPELLPIIYTPVVGEACQRHSDLYLRSHGLYLSWHDR 110
Query: 434 GHVYDVLKNWPETDVRAIVVTDGER 508
+ D + E +V IV++DGER
Sbjct: 111 DDL-DAIFAAVEQEVDVIVISDGER 134
>UniRef50_Q5KBK5 Cluster: Nad-dependent malic enzyme, putative; n=2;
Filobasidiella neoformans|Rep: Nad-dependent malic
enzyme, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 584
Score = 71.7 bits (168), Expect = 2e-11
Identities = 30/56 (53%), Positives = 41/56 (73%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LG+GD G+ G+GI K +Y+ + G+ P +CL IT+DVGTN Q +L+DPLYIG R
Sbjct: 171 LGIGDQGSGGIGISGAKAVIYSLIAGVDPAKCLAITLDVGTNNQDLLNDPLYIGYR 226
Score = 51.2 bits (117), Expect = 2e-05
Identities = 29/82 (35%), Positives = 44/82 (53%), Gaps = 1/82 (1%)
Frame = +2
Query: 263 YLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFIT-IHDKGH 439
+L + +N LFY + ++ EM PIVYTPT A + ++RR GL++T +K
Sbjct: 87 FLQSMKAQNWTLFYALLQAHLVEMFPIVYTPTEADAIADYSHLFRRSEGLYLTPPGEKNM 146
Query: 440 VYDVLKNWPETDVRAIVVTDGE 505
D L ++ IVV+DGE
Sbjct: 147 EEDFLDACEGRELELIVVSDGE 168
>UniRef50_Q95061 Cluster: Malic enzyme; n=2; Giardia
intestinalis|Rep: Malic enzyme - Giardia lamblia
(Giardia intestinalis)
Length = 557
Score = 68.5 bits (160), Expect = 1e-10
Identities = 36/88 (40%), Positives = 51/88 (57%), Gaps = 1/88 (1%)
Frame = +2
Query: 248 T*QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYR-RPRGLFITI 424
T +++YL L + NE LF F + E++PIVYTPTVG AC + L+++ PRG ++
Sbjct: 59 TEKWLYLTRLQEVNETLFSGFCLKYLKEVLPIVYTPTVGTACSNYSLLWQGYPRGFYLNR 118
Query: 425 HDKGHVYDVLKNWPETDVRAIVVTDGER 508
G V + WP + R IV TDG R
Sbjct: 119 THLGKVKQIFDQWPYSP-RIIVATDGTR 145
Score = 62.1 bits (144), Expect = 1e-08
Identities = 29/55 (52%), Positives = 35/55 (63%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGL 675
LGLGDLG G I VGKL LY+ GG P LPI+ D G NT + +DP Y+G+
Sbjct: 147 LGLGDLGTGGHQICVGKLTLYSLGGGFAPEHTLPISFDFGCNTDKIREDPHYLGI 201
>UniRef50_Q6AL43 Cluster: Related to NAD-dependent malic enzyme;
n=1; Desulfotalea psychrophila|Rep: Related to
NAD-dependent malic enzyme - Desulfotalea psychrophila
Length = 578
Score = 68.1 bits (159), Expect = 2e-10
Identities = 30/84 (35%), Positives = 49/84 (58%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
+YI++ L DRN L + + ++ + M I+YTPTVGLA QK+ ++R+ GL +
Sbjct: 81 KYIFIRSLFDRNVTLAHALIQSDLEKFMGIIYTPTVGLAVQKYSAMFRQANGLHFSPDTI 140
Query: 434 GHVYDVLKNWPETDVRAIVVTDGE 505
D+L+ + D+R VVTD +
Sbjct: 141 DQAEDILRRFAHRDIRVAVVTDNQ 164
Score = 65.3 bits (152), Expect = 1e-09
Identities = 29/56 (51%), Positives = 40/56 (71%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LG+GD GA G+ I +GKL LYT GI P CLPI++D+GT+ +++L D Y+G R
Sbjct: 167 LGIGDQGAGGIAICLGKLMLYTQGAGIAPWHCLPISLDIGTDNEALLADKHYLGWR 222
>UniRef50_Q8Y5Y8 Cluster: Lmo1915 protein; n=15; Firmicutes|Rep:
Lmo1915 protein - Listeria monocytogenes
Length = 547
Score = 67.7 bits (158), Expect = 2e-10
Identities = 28/54 (51%), Positives = 39/54 (72%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 672
LG+GD G+ I VGKLA+YT G+ P + LP+ ID GTN +++L+DPLY+G
Sbjct: 151 LGIGDWSVNGVKIAVGKLAVYTVAAGLAPDRVLPVVIDAGTNNETLLNDPLYLG 204
Score = 51.6 bits (118), Expect = 2e-05
Identities = 36/129 (27%), Positives = 60/129 (46%), Gaps = 3/129 (2%)
Frame = +2
Query: 164 PRVVTTTSQDARGAG*TMQALDRQIRKST*QYIYLMGLLDRNEHLFYRFVADNVAEMMPI 343
P ++ T Q A ++ L+ + K + L L + N L+Y V NV + +PI
Sbjct: 36 PPIIETIEQQAVRIETQIENLETPLHK----HRLLTNLYNENRTLYYYVVTKNVTDYLPI 91
Query: 344 VYTPTVGLACQKFGLVYRRP-RGLFITIHDKGHVYDVLKNWPET--DVRAIVVTDGERFW 514
+YTPT+G A ++ Y P LF+ + +KN+ + ++ IV+TDGE
Sbjct: 92 IYTPTIGDAVIQYHKDYTAPDEALFVDAFAPEKLSASIKNYAKNNPNIDMIVITDGEGVL 151
Query: 515 VWATWAHAG 541
W+ G
Sbjct: 152 GIGDWSVNG 160
Score = 33.5 bits (73), Expect = 4.9
Identities = 15/29 (51%), Positives = 20/29 (68%)
Frame = +1
Query: 85 SGLDHLKHPGLNKGMAFTIEERQSWGSTG 171
SG D++ +P LNKG AF+ EER S+ G
Sbjct: 5 SGFDYMNNPLLNKGTAFSKEERASYQLDG 33
>UniRef50_A3YYQ0 Cluster: Malate oxidoreductase; n=1; Synechococcus
sp. WH 5701|Rep: Malate oxidoreductase - Synechococcus
sp. WH 5701
Length = 517
Score = 67.7 bits (158), Expect = 2e-10
Identities = 35/91 (38%), Positives = 52/91 (57%), Gaps = 1/91 (1%)
Frame = +2
Query: 236 IRKST*QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPR-GL 412
+R ++ + + L N LF+RF+AD++ +MPIVYTPTVG A Q+F L YR P G+
Sbjct: 18 LRNDLERFRFAVALRQANLTLFHRFLADHIEAVMPIVYTPTVGAAIQRFSLDYRTPSGGV 77
Query: 413 FITIHDKGHVYDVLKNWPETDVRAIVVTDGE 505
F+ D + VL V I++TD +
Sbjct: 78 FLAAPDLERIESVLSQAATGPVDLILITDSQ 108
Score = 60.5 bits (140), Expect = 4e-08
Identities = 27/56 (48%), Positives = 39/56 (69%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LG+GD G G+ I +GKLA+YT G+ P + LP+ +DVGT+ +L++PLY G R
Sbjct: 111 LGIGDQGIGGIEICLGKLAVYTLCAGLDPARVLPLVLDVGTDRVELLENPLYPGWR 166
>UniRef50_A2QY66 Cluster: Malic enzyme; n=2; cellular organisms|Rep:
Malic enzyme - Aspergillus niger
Length = 609
Score = 66.9 bits (156), Expect = 4e-10
Identities = 35/115 (30%), Positives = 63/115 (54%), Gaps = 1/115 (0%)
Frame = +2
Query: 164 PRVVTTTSQDARGAG*TMQALDRQIRKST*QYIYLMGLLDRNEHLFYRFVADNVAEMMPI 343
P + T + + A + D + K+T ++ + +NE L+Y+ + ++ EM+ I
Sbjct: 87 PPNIQTLEEQVQRAYEQYSSRDNDLAKNT----FMASMKAQNEVLYYKLIDTHLKEMLSI 142
Query: 344 VYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPE-TDVRAIVVTDGE 505
+YTPT G A Q + ++R+P G F+ I D+ + + L N+ +V IVV+DGE
Sbjct: 143 IYTPTEGDAIQNYSRLFRKPEGCFLNIRDQDRIEECLSNFSRGEEVDYIVVSDGE 197
Score = 59.3 bits (137), Expect = 9e-08
Identities = 28/56 (50%), Positives = 37/56 (66%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LG+GD G + I V KLAL T GI P + LP+ +D GT+ +S+L D LY+GLR
Sbjct: 200 LGIGDQGVGAILISVAKLALTTLCAGIHPSRQLPVVLDCGTDNESLLTDELYLGLR 255
Score = 33.1 bits (72), Expect = 6.4
Identities = 15/49 (30%), Positives = 22/49 (44%)
Frame = +3
Query: 123 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNSTSIL 269
G F +HGLLPP ++T EEQV+ +N L + +
Sbjct: 69 GSAFTEEERKTFKLHGLLPPNIQTLEEQVQRAYEQYSSRDNDLAKNTFM 117
>UniRef50_Q2HCG7 Cluster: Malic enzyme; n=1; Chaetomium
globosum|Rep: Malic enzyme - Chaetomium globosum (Soil
fungus)
Length = 586
Score = 66.5 bits (155), Expect = 6e-10
Identities = 29/56 (51%), Positives = 41/56 (73%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LG+GD G G+ I V KLAL T GI P++ LP+ +D GT+ +++L+DPLY+GLR
Sbjct: 187 LGIGDQGCGGILISVAKLALMTLCAGIHPNRVLPVVLDCGTDNETLLNDPLYLGLR 242
Score = 57.2 bits (132), Expect = 3e-07
Identities = 33/102 (32%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +2
Query: 212 TMQALDRQIRKST*QYIYLMGLLDRNEHLFYRFVADNVA--EMMPIVYTPTVGLACQKFG 385
++Q LD+Q++++ QY L +N L + V +M +VYTPT G A + F
Sbjct: 65 SIQTLDQQVQRAYEQYSARPDDLAKNTFLTSMKEQNEVLYFKMFSVVYTPTEGDAIENFS 124
Query: 386 LVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERF 511
++RRP+G+F+ +HD V+ L W D +V G F
Sbjct: 125 RLFRRPQGVFLNVHDCDRVHHDLSLWGMPDDIDYIVVTGATF 166
>UniRef50_Q48796 Cluster: Malolactic enzyme; n=49; Bacteria|Rep:
Malolactic enzyme - Oenococcus oeni (Leuconostoc oenos)
Length = 541
Score = 63.3 bits (147), Expect = 5e-09
Identities = 27/54 (50%), Positives = 35/54 (64%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 672
LG+GD G G+ I VGKL +YT GI P L + ID GTN + +L DP+Y+G
Sbjct: 148 LGIGDWGVQGVDIAVGKLMVYTVAAGIDPSTVLAVVIDAGTNNEKLLKDPMYLG 201
Score = 56.8 bits (131), Expect = 5e-07
Identities = 29/96 (30%), Positives = 50/96 (52%), Gaps = 2/96 (2%)
Frame = +2
Query: 260 IYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRG-LFITIHDKG 436
++LM + + N LFY+ + +V E MPIVY PT+ + + ++ P+G F+ I+
Sbjct: 62 LFLMEIFNTNHVLFYKLFSQHVVEFMPIVYDPTIADTIENYSELFVEPQGAAFLDINHPE 121
Query: 437 HVYDVLKNWPE-TDVRAIVVTDGERFWVWATWAHAG 541
++ LKN D++ +VV+D E W G
Sbjct: 122 NIQSTLKNAANGRDIKLLVVSDAEGILGIGDWGVQG 157
>UniRef50_P40375 Cluster: NAD-dependent malic enzyme; n=3;
Schizosaccharomyces pombe|Rep: NAD-dependent malic
enzyme - Schizosaccharomyces pombe (Fission yeast)
Length = 565
Score = 62.5 bits (145), Expect = 9e-09
Identities = 31/85 (36%), Positives = 52/85 (61%), Gaps = 3/85 (3%)
Frame = +2
Query: 260 IYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITI--HDK 433
+YL L N+ LFY ++ ++ EM+PI+YTPT G A ++F +YR P G ++ I +D
Sbjct: 74 LYLSQLSVTNQTLFYALISQHLIEMIPIIYTPTEGDAIKQFSDIYRYPEGCYLDIDHNDL 133
Query: 434 GHVYDVLKNWPETD-VRAIVVTDGE 505
++ L + ++D V I++TD E
Sbjct: 134 SYIKQQLSEFGKSDSVEYIIITDSE 158
Score = 50.8 bits (116), Expect = 3e-05
Identities = 25/56 (44%), Positives = 35/56 (62%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
LG+GD G G+ I V K L T G+ P++ LPI +DVGTN ++ + Y+GLR
Sbjct: 161 LGIGDQGVGGVLISVAKGHLMTLCAGLDPNRFLPIVLDVGTNNETHRKNHQYMGLR 216
>UniRef50_P36013 Cluster: NAD-dependent malic enzyme, mitochondrial
precursor; n=15; Saccharomycetales|Rep: NAD-dependent
malic enzyme, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 669
Score = 60.1 bits (139), Expect = 5e-08
Identities = 27/54 (50%), Positives = 36/54 (66%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 672
LG+GD G G+ I + KLAL T GGI P + LP+ +DVGTN + + D LY+G
Sbjct: 243 LGIGDQGIGGVRIAISKLALMTLCGGIHPGRVLPVCLDVGTNNKKLARDELYMG 296
Score = 50.0 bits (114), Expect = 5e-05
Identities = 25/82 (30%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
Frame = +2
Query: 263 YLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHV 442
++ L +N+ L++ + ++ E++PI+YTPT G A + +R+P G+F+ I + +
Sbjct: 159 FMTSLRVQNKVLYFALIRRHIKELVPIIYTPTEGDAIAAYSHRFRKPEGVFLDITEPDSI 218
Query: 443 YDVLKNW-PETDVRAIVVTDGE 505
L + + DV IVV+D E
Sbjct: 219 ECRLATYGGDKDVDYIVVSDSE 240
>UniRef50_Q5KEY3 Cluster: Malic enzyme; n=1; Filobasidiella
neoformans|Rep: Malic enzyme - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 629
Score = 59.3 bits (137), Expect = 9e-08
Identities = 25/54 (46%), Positives = 35/54 (64%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIG 672
LG+GD G G+ I K ALYT GI P++ LP+ +D GT+ ++ DPLY+G
Sbjct: 210 LGIGDQGVGGITISTSKAALYTLGAGINPNRILPVVLDCGTDNHALFSDPLYMG 263
Score = 50.4 bits (115), Expect = 4e-05
Identities = 30/100 (30%), Positives = 53/100 (53%), Gaps = 16/100 (16%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHD- 430
++ +L L D+N+ LFYR + D + E++ ++YTP A + ++RRP G +I+ +
Sbjct: 108 KHAFLASLRDQNQVLFYRLMQDRLKELLGVLYTPGAAEAVAGYSSLFRRPVGCYISFPNQ 167
Query: 431 -------KGHVYDVLK--------NWPETDVRAIVVTDGE 505
+GH+ DV + N P+ + +VVTD E
Sbjct: 168 DGMRAQLEGHLTDVNRTADVAYDSNKPDDAIDLVVVTDAE 207
>UniRef50_Q7K3R0 Cluster: Malic enzyme; n=2; Sophophora|Rep: Malic
enzyme - Drosophila melanogaster (Fruit fly)
Length = 633
Score = 56.0 bits (129), Expect = 8e-07
Identities = 26/56 (46%), Positives = 33/56 (58%)
Frame = +1
Query: 511 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLR 678
L +GDLG M I L GGI P CL + +DVGTN + +L+DP+Y GLR
Sbjct: 214 LSVGDLGVDEMPILFSNLHQNVVYGGIHPAYCLAVMLDVGTNNEELLNDPMYTGLR 269
Score = 55.6 bits (128), Expect = 1e-06
Identities = 29/83 (34%), Positives = 42/83 (50%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 433
QYIYL L RN LFY + N +P+ +++ +GL+I I D
Sbjct: 128 QYIYLTYLSRRNRRLFYYLLLSNPDRFVPMTDASGSIDLLMVHRMIHSMGQGLYICIKDL 187
Query: 434 GHVYDVLKNWPETDVRAIVVTDG 502
GHV +L NWP VR ++V++G
Sbjct: 188 GHVSQILSNWPFRCVRCLLVSNG 210
Score = 37.9 bits (84), Expect = 0.23
Identities = 17/41 (41%), Positives = 23/41 (56%)
Frame = +3
Query: 123 GYGFYHRRASVLGIHGLLPPRVKTQEEQVELCKLSIDRYEN 245
G F VL IHGLLP V+T +EQ E+C ++ + N
Sbjct: 84 GLAFTLNERRVLSIHGLLPVAVRTIDEQAEICSNLLESFTN 124
>UniRef50_Q9S4T5 Cluster: NAD-malate oxidoreductase homolog; n=15;
Legionellales|Rep: NAD-malate oxidoreductase homolog -
Legionella pneumophila
Length = 117
Score = 48.0 bits (109), Expect = 2e-04
Identities = 19/39 (48%), Positives = 30/39 (76%)
Frame = +2
Query: 254 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLA 370
Q+IYL L D+N+ +FY+ ++ ++ EM+PI+YTP VG A
Sbjct: 79 QHIYLNNLHDKNQIVFYKLLSRHLGEMLPIIYTPIVGAA 117
Score = 35.1 bits (77), Expect = 1.6
Identities = 25/64 (39%), Positives = 34/64 (53%), Gaps = 5/64 (7%)
Frame = +1
Query: 76 SGLSGLDHLKHPGLNKGMAFTIEERQSWGSTGCYHH-----ESRRKRSRLNYASSRSTDT 240
+ L G L P LNKG AFT EER+ +G G H + + KR+ L Y SS +T
Sbjct: 19 TSLCGKPLLTTPQLNKGTAFTQEERKDFGLLGKLPHRVETLDEQVKRAYLQY-SSYTTRL 77
Query: 241 KIHL 252
+ H+
Sbjct: 78 QQHI 81
>UniRef50_Q8S484 Cluster: Putative NADP-dependent malic enzyme; n=1;
Zea mays|Rep: Putative NADP-dependent malic enzyme - Zea
mays (Maize)
Length = 309
Score = 44.8 bits (101), Expect = 0.002
Identities = 28/74 (37%), Positives = 36/74 (48%)
Frame = +2
Query: 287 NEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWP 466
+E LFY+ + DNV E++P VYT T G V DVLKNWP
Sbjct: 225 DERLFYKLLIDNVVELLPFVYTTT-------------------------GKVLDVLKNWP 259
Query: 467 ETDVRAIVVTDGER 508
+++ I VTD ER
Sbjct: 260 HRNIQVIFVTDSER 273
>UniRef50_UPI0000DB7FF6 Cluster: PREDICTED: hypothetical protein,
partial; n=1; Apis mellifera|Rep: PREDICTED:
hypothetical protein, partial - Apis mellifera
Length = 95
Score = 42.3 bits (95), Expect = 0.011
Identities = 19/37 (51%), Positives = 26/37 (70%)
Frame = +1
Query: 13 TYSEMERDRIGLWGSGDGQPTSGLSGLDHLKHPGLNK 123
T S ++RD++G G GD ++ L GLDHLK+P LNK
Sbjct: 59 TMSSVQRDQLGQRGHGDAMCSNLLRGLDHLKNPRLNK 95
>UniRef50_UPI0000DA40E4 Cluster: PREDICTED: hypothetical protein;
n=2; Rattus norvegicus|Rep: PREDICTED: hypothetical
protein - Rattus norvegicus
Length = 193
Score = 34.3 bits (75), Expect = 2.8
Identities = 21/52 (40%), Positives = 26/52 (50%)
Frame = -1
Query: 560 LPTGMPIPHAPKSPRPRNVLRRLQQWRGRPSPASS*EHRIHVPYRGS**RGP 405
LPT P P+ RP R +WRG P+P + + R P RGS RGP
Sbjct: 105 LPT--PCKRTPRRTRPAPCSAR--RWRGHPAPRAQWQRREGRPRRGSQARGP 152
>UniRef50_Q4SN44 Cluster: Chromosome 8 SCAF14543, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 8 SCAF14543, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 212
Score = 34.3 bits (75), Expect = 2.8
Identities = 19/58 (32%), Positives = 26/58 (44%), Gaps = 2/58 (3%)
Frame = +2
Query: 509 FWVWATWAHAGWASLWAN--SRSTPRSEASSRISVCPSLSTWVRTPSRCWTTRCTSGS 676
+W A A WA W+ SR R + + P+ W R+ S W T C+SGS
Sbjct: 147 WWSAAGTAGGAWAGFWSRAWSRKRVRGALTGYTHMSPTPPRWGRSSSGSWAT-CSSGS 203
>UniRef50_A1CBX6 Cluster: RNA binding domain protein; n=1;
Aspergillus clavatus|Rep: RNA binding domain protein -
Aspergillus clavatus
Length = 264
Score = 33.9 bits (74), Expect = 3.7
Identities = 22/60 (36%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Frame = -1
Query: 536 HAPKSPRPRNVLRRLQQWRGRPSPASS*EHRIHVPYRGS**RGPLVG-GTQGRTSDRPGQ 360
HAP P P+ + R+ Q + +P PA++ + RG RG G GRTS+RP Q
Sbjct: 147 HAPSVPAPKPLGERVAQVKSQPKPATA--AKTAAAARGRGRRGRRGGAAATGRTSNRPKQ 204
>UniRef50_UPI0000EB0F1E Cluster: UPI0000EB0F1E related cluster; n=1;
Canis lupus familiaris|Rep: UPI0000EB0F1E UniRef100
entry - Canis familiaris
Length = 474
Score = 33.5 bits (73), Expect = 4.9
Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 1/65 (1%)
Frame = -3
Query: 552 RDAHPACAQ-VAQTQKRSPSVTTMARTSVSGQFLRTSYTCPLSWIVMKRPLGRRYTRPNF 376
RD HPA AQ + K + S+T+ +++ Q + TC +++ +K PL +
Sbjct: 47 RDEHPASAQYLVINDKGNYSITSKVWVTLAHQDILLGITCEVTYTALKEPLRKTMNLSQV 106
Query: 375 *QARP 361
QA P
Sbjct: 107 LQAYP 111
>UniRef50_Q17IF3 Cluster: Putative uncharacterized protein; n=1;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 2052
Score = 33.5 bits (73), Expect = 4.9
Identities = 16/64 (25%), Positives = 31/64 (48%)
Frame = +3
Query: 369 PVRSSALCTADQGASSSRSTIRDMYTMFLRTGRRRTSAPLL*PTENVSGSGRLGRMRDGH 548
PV+S++ C + + S + ++M++MF+ G P P S + +G ++
Sbjct: 581 PVKSASSCNSSRAESVEKDAKKNMFSMFIDIGNEAAPKPSSAP-RRFSAASTVGPTKEES 639
Query: 549 PCGQ 560
P GQ
Sbjct: 640 PIGQ 643
>UniRef50_Q7WLT2 Cluster: Putative uncharacterized protein; n=1;
Bordetella bronchiseptica|Rep: Putative uncharacterized
protein - Bordetella bronchiseptica (Alcaligenes
bronchisepticus)
Length = 215
Score = 33.1 bits (72), Expect = 6.4
Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
Frame = +2
Query: 428 DKGHVYDVLKNWP-ETDVRAIVVTDGERFWVWATWAHA 538
D GH + V K+ P E V+ G+R WV TWA+A
Sbjct: 49 DDGHAFMVYKHMPHERAVKCPYGQPGDRLWVRETWAYA 86
>UniRef50_Q6ZCE9 Cluster: Putative uncharacterized protein
P0486F07.41; n=1; Oryza sativa (japonica
cultivar-group)|Rep: Putative uncharacterized protein
P0486F07.41 - Oryza sativa subsp. japonica (Rice)
Length = 292
Score = 33.1 bits (72), Expect = 6.4
Identities = 15/35 (42%), Positives = 19/35 (54%)
Frame = -3
Query: 603 LMRLDASERGVEREFAHRDAHPACAQVAQTQKRSP 499
L+RL A GV+ AHR AHPA V + +P
Sbjct: 255 LLRLPALAMGVDGAVAHRGAHPAATHVVHRAEEAP 289
>UniRef50_Q1EI20 Cluster: Putative uncharacterized protein; n=2;
root|Rep: Putative uncharacterized protein - uncultured
organism
Length = 302
Score = 32.7 bits (71), Expect = 8.5
Identities = 10/20 (50%), Positives = 16/20 (80%)
Frame = +2
Query: 407 GLFITIHDKGHVYDVLKNWP 466
G+++TI + G + D+LKNWP
Sbjct: 210 GVYLTIREPGQITDILKNWP 229
>UniRef50_A3K0U7 Cluster: Putative uncharacterized protein; n=2;
Rhodobacteraceae|Rep: Putative uncharacterized protein -
Sagittula stellata E-37
Length = 315
Score = 32.7 bits (71), Expect = 8.5
Identities = 24/97 (24%), Positives = 38/97 (39%), Gaps = 3/97 (3%)
Frame = -2
Query: 496 GYNNGADVRLRPV-LKNIVYMSLIVDRDEEAPWSAVHKAELLTGQANRRSVHNWHHFSHV 320
G+ A L P+ ++ + S R PW + A L+ R +H W+
Sbjct: 51 GFARAAQEALPPLPCTDLDWPSYAAGRTRGLPWFLL-SARLIASSGRRVMLHGWNGSDSA 109
Query: 319 IRDETVEQMLIAVQEPHKIDVLL--SGFSYLSIESLH 215
+RD + V++P L G YL +E LH
Sbjct: 110 VRDGLDTLGISVVRKPGDAAAALDRDGIVYLPLEDLH 146
>UniRef50_A0WC26 Cluster: Multi-sensor hybrid histidine kinase
precursor; n=2; Geobacter lovleyi SZ|Rep: Multi-sensor
hybrid histidine kinase precursor - Geobacter lovleyi SZ
Length = 1007
Score = 32.7 bits (71), Expect = 8.5
Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Frame = +2
Query: 362 GLACQKFGLVYRRPRGL-FITIHDKGHVYDVLKNWPETDVRAIVVTDG 502
G+ K +YR R FI HD+ H+++ +KN PE + IV DG
Sbjct: 198 GIFDSKGVFLYRTARANEFIGKHDQPHLFEQMKNGPEEGIIDIVSNDG 245
>UniRef50_A0K1T3 Cluster: Allergen V5/Tpx-1 family protein
precursor; n=2; Arthrobacter|Rep: Allergen V5/Tpx-1
family protein precursor - Arthrobacter sp. (strain
FB24)
Length = 588
Score = 32.7 bits (71), Expect = 8.5
Identities = 18/62 (29%), Positives = 28/62 (45%)
Frame = +2
Query: 368 ACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERFWVWATWAHAGWA 547
A Q G + + LF+T D+ V+D+L W + V + G F T +GWA
Sbjct: 375 AQQVVGTGFGSAKELFVTDWDRDGVFDILVQWTDGRVTLHAGSVGGGFLPGVTLGQSGWA 434
Query: 548 SL 553
+
Sbjct: 435 GM 436
>UniRef50_Q9LT49 Cluster: Arabidopsis thaliana genomic DNA,
chromosome 3, P1 clone: MOE17; n=3; Arabidopsis
thaliana|Rep: Arabidopsis thaliana genomic DNA,
chromosome 3, P1 clone: MOE17 - Arabidopsis thaliana
(Mouse-ear cress)
Length = 814
Score = 32.7 bits (71), Expect = 8.5
Identities = 22/59 (37%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
Frame = +1
Query: 1 GGKCTYSEMERDRIGLWGSGDGQPTSGLS-GLDHLKHPGLNK-GMAFTIEERQSWGSTG 171
GG +Y+E R G+ DG P GLS GLDHL ++K A +++R+ G+ G
Sbjct: 448 GGGMSYAEALLHRFGILNH-DGGPGEGLSRGLDHLSSGPMSKLFKASIVDDRKKDGTPG 505
>UniRef50_Q6ZSU3 Cluster: CDNA FLJ45206 fis, clone BRCAN2010581;
n=1; Homo sapiens|Rep: CDNA FLJ45206 fis, clone
BRCAN2010581 - Homo sapiens (Human)
Length = 123
Score = 32.7 bits (71), Expect = 8.5
Identities = 22/60 (36%), Positives = 31/60 (51%)
Frame = +3
Query: 348 TLRRLAWPVRSSALCTADQGASSSRSTIRDMYTMFLRTGRRRTSAPLL*PTENVSGSGRL 527
T RR W R S++ +A SS+R T R T R+ RRR +AP P+ + S R+
Sbjct: 7 TTRRPPWG-RFSSVSSAS--VSSTRKTWRTRSTSCCRSSRRRVAAPFCTPSASTEPSARM 63
>UniRef50_A1CKF3 Cluster: Stress response protein (Ish1), putative;
n=5; Pezizomycotina|Rep: Stress response protein (Ish1),
putative - Aspergillus clavatus
Length = 516
Score = 32.7 bits (71), Expect = 8.5
Identities = 17/52 (32%), Positives = 24/52 (46%)
Frame = -2
Query: 412 EAPWSAVHKAELLTGQANRRSVHNWHHFSHVIRDETVEQMLIAVQEPHKIDV 257
+A W + K + GQA + HNWHH I D + L A + H + V
Sbjct: 63 KANWDS--KVQKPLGQAAEHTTHNWHHAKEWIFDTWSDSQLKAFLDRHGVPV 112
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 814,009,605
Number of Sequences: 1657284
Number of extensions: 19341648
Number of successful extensions: 66639
Number of sequences better than 10.0: 75
Number of HSP's better than 10.0 without gapping: 61988
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 66538
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 52892566912
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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