Bombyx BLAST Result against human

BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= e40h0626
         (790 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

U85048-1|AAB96381.1|  721|Homo sapiens cyclic AMP specific phosp...   159   1e-38
M97515-1|AAA36426.1|  564|Homo sapiens phosphodiesterase protein.     159   1e-38
L20971-1|AAA03593.1|  564|Homo sapiens phosphodiesterase protein.     159   1e-38
L20966-1|AAA03589.1|  736|Homo sapiens phosphodiesterase protein.     159   1e-38
L12686-1|AAA35643.1|  606|Homo sapiens 3',5'-cyclic AMP phosphod...   159   1e-38
EF595686-1|ABQ85407.1|  503|Homo sapiens cAMP-specific phosphodi...   159   1e-38
BC105040-1|AAI05041.1|  736|Homo sapiens phosphodiesterase 4B, c...   159   1e-38
BC101480-1|AAI01481.1|  736|Homo sapiens phosphodiesterase 4B, c...   159   1e-38
AL592285-3|CAH70628.1|  721|Homo sapiens phosphodiesterase 4B, c...   159   1e-38
AL592285-1|CAH70626.1|  736|Homo sapiens phosphodiesterase 4B, c...   159   1e-38
AL359701-3|CAI23101.1|  721|Homo sapiens phosphodiesterase 4B, c...   159   1e-38
AL359701-2|CAI23100.1|  564|Homo sapiens phosphodiesterase 4B, c...   159   1e-38
AL359701-1|CAI23099.1|  736|Homo sapiens phosphodiesterase 4B, c...   159   1e-38
AL357273-3|CAH73004.1|  721|Homo sapiens phosphodiesterase 4B, c...   159   1e-38
AL357273-1|CAH73002.1|  736|Homo sapiens phosphodiesterase 4B, c...   159   1e-38
AL109926-4|CAI21751.1|  721|Homo sapiens phosphodiesterase 4B, c...   159   1e-38
AL109926-3|CAI21750.1|  564|Homo sapiens phosphodiesterase 4B, c...   159   1e-38
AL109926-2|CAI21749.1|  736|Homo sapiens phosphodiesterase 4B, c...   159   1e-38
AB209081-1|BAD92318.1|  726|Homo sapiens phosphodiesterase 4B, c...   159   1e-38
U97584-1|AAC25679.1|  647|Homo sapiens cyclic AMP-specific phosp...   156   7e-38
U68532-1|AAC63832.1|  647|Homo sapiens cyclic AMP specific phosp...   156   7e-38
U18088-1|AAA98540.1|  323|Homo sapiens 3',5'-cyclic AMP phosphod...   156   7e-38
U18087-1|AAC50458.1|  686|Homo sapiens 3',5'-cyclic AMP phosphod...   156   7e-38
S75213-1|AAB33798.1|  667|Homo sapiens type-IVA cyclic AMP speci...   156   7e-38
M37744-1|AAA69697.1|  775|Homo sapiens protein ( Human cyclic AM...   156   7e-38
L20965-1|AAA03588.1|  886|Homo sapiens phosphodiesterase protein.     156   7e-38
BC038234-1|AAH38234.1|  647|Homo sapiens phosphodiesterase 4A, c...   156   7e-38
BC019864-1|AAH19864.1|  647|Homo sapiens phosphodiesterase 4A, c...   156   7e-38
AY618547-1|AAU82096.1|  860|Homo sapiens cyclic AMP phosphodiest...   156   7e-38
AY593872-1|AAT00628.1|  864|Homo sapiens cAMP-specific phosphodi...   156   7e-38
AF073745-1|AAD34217.2|  825|Homo sapiens cyclic AMP-specific pho...   156   7e-38
AF069491-4|AAC35014.1|  323|Homo sapiens cAMP specific phosphodi...   156   7e-38
AF069491-3|AAC35013.1|  647|Homo sapiens cAMP specific phosphodi...   156   7e-38
AF069491-2|AAC35015.1|  860|Homo sapiens putative novel cAMP spe...   156   7e-38
AF069491-1|AAC35012.1|  886|Homo sapiens cAMP specific phosphodi...   156   7e-38
U50159-1|AAA97892.1|  673|Homo sapiens cAMP-specific phoshodiest...   152   2e-36
U50158-1|AAA97891.1|  507|Homo sapiens cAMP-specific phosphodies...   152   2e-36
U50157-1|AAA97890.1|  585|Homo sapiens cAMP-specific phosphodies...   152   2e-36
U02882-1|AAC13745.1|  604|Homo sapiens 3',5'-cyclic AMP phosphod...   152   2e-36
L20970-1|AAA03592.1|  673|Homo sapiens phosphodiesterase protein.     152   2e-36
L20969-1|AAC00042.1|  809|Homo sapiens cyclic AMP phosphodiester...   152   2e-36
AY388960-1|AAQ90404.1|  679|Homo sapiens cAMP-specific phosphodi...   152   2e-36
AY245867-1|AAP75761.1|  679|Homo sapiens cAMP-specific phosphodi...   152   2e-36
AY245866-1|AAP75760.1|  748|Homo sapiens cAMP-specific phosphodi...   152   2e-36
AF536976-1|AAN10118.1|  748|Homo sapiens cAMP-specific phosphodi...   152   2e-36
AF536975-1|AAN10117.1|  518|Homo sapiens cAMP-specific phosphodi...   152   2e-36
AF012074-1|AAC00070.1|  507|Homo sapiens cAMP-specific phosphodi...   152   2e-36
AF012073-1|AAC00069.1|  745|Homo sapiens cAMP-specific phosphodi...   152   2e-36
BC036319-1|AAH36319.1|  518|Homo sapiens PDE4D protein protein.       151   4e-36
AF536977-1|AAN10119.1|  687|Homo sapiens cAMP-specific phosphodi...   149   1e-35
U88713-1|AAC51916.1|  700|Homo sapiens phosphodiesterase 4C prot...   146   8e-35
U88712-1|AAC51915.1|  606|Homo sapiens phosphodiesterase 4C prot...   146   8e-35
U66349-1|AAB96878.1|  427|Homo sapiens PDE4C-delta109 protein.        146   8e-35
U66348-1|AAB96877.1|  518|Homo sapiens PDE4C-delta54 protein.         146   8e-35
U66347-1|AAB96876.1|  426|Homo sapiens PDE4C-426 protein.             146   8e-35
U66346-1|AAB96875.1|  791|Homo sapiens PDE4C-791 protein.             146   8e-35
BC109068-1|AAI09069.1|  549|Homo sapiens PDE4C protein protein.       146   8e-35
BC109067-1|AAI09068.1|  481|Homo sapiens PDE4C protein protein.       146   8e-35
AF157816-3|AAD47055.1|  606|Homo sapiens cAMP specific phosphodi...   146   8e-35
AF157816-2|AAD47054.1|  680|Homo sapiens cAMP specific phosphodi...   146   8e-35
AF157816-1|AAD47053.1|  712|Homo sapiens cAMP specific phosphodi...   146   8e-35
AC005759-5|AAC83049.1|  426|Homo sapiens PDE4C-426 protein.           146   8e-35
AC005759-4|AAC83048.1|  427|Homo sapiens PDE4C-delta109 protein.      146   8e-35
AC005759-3|AAC83051.1|  518|Homo sapiens PDE4C-delta54 protein.       146   8e-35
AC005759-1|AAC83050.1|  782|Homo sapiens PDE4C-791 protein.           146   8e-35
Z46632-1|CAA86601.1|  712|Homo sapiens 3',5'-cyclic AMP phosphod...   144   4e-34
AC005759-2|AAC83047.1|  710|Homo sapiens CN4C_HUMAN protein.          137   4e-32
U86078-1|AAC51872.1|  536|Homo sapiens calmodulin-stimulated pho...    93   1e-18
U56976-1|AAC50769.1|  536|Homo sapiens calmodulin dependent phos...    93   1e-18
U40584-1|AAB50018.1|  184|Homo sapiens calcium/calmodulin-stimul...    93   1e-18
BX538092-1|CAD98011.1|  399|Homo sapiens hypothetical protein pr...    93   1e-18
BC032226-1|AAH32226.1|  536|Homo sapiens phosphodiesterase 1B, c...    93   1e-18
AJ401609-1|CAC82207.1|  516|Homo sapiens 3'5' cyclic nucleotide ...    93   1e-18
BC075822-1|AAH75822.1|  829|Homo sapiens phosphodiesterase 8A pr...    92   2e-18
BC060762-1|AAH60762.1|  829|Homo sapiens phosphodiesterase 8A pr...    92   2e-18
BC048317-1|AAH48317.1|  305|Homo sapiens PDE8A protein protein.        92   2e-18
AF388187-1|AAL18614.1|  582|Homo sapiens cAMP phosphodiesterase ...    92   2e-18
AF388186-1|AAL18613.1|  582|Homo sapiens cAMP phosphodiesterase ...    92   2e-18
AF388185-1|AAL18612.1|  449|Homo sapiens cAMP phosphodiesterase ...    92   2e-18
AF388184-1|AAL18611.1|  783|Homo sapiens cAMP phosphodiesterase ...    92   2e-18
AF388183-1|AAL18610.1|  829|Homo sapiens cAMP phosphodiesterase ...    92   2e-18
AF332653-1|AAK57641.1|  829|Homo sapiens cAMP-specific cyclic nu...    92   2e-18
AF056490-1|AAC39763.1|  713|Homo sapiens cAMP-specific phosphodi...    92   2e-18
BC047627-1|AAH47627.1|  241|Homo sapiens PDE8B protein protein.        91   3e-18
BC035144-1|AAH35144.1|  385|Homo sapiens PDE8B protein protein.        91   3e-18
AY423729-1|AAS00492.1|  350|Homo sapiens proliferation-inducing ...    91   3e-18
AY129950-3|AAN71727.1|  788|Homo sapiens cAMP-specific phosphodi...    91   3e-18
AY129950-2|AAN71726.1|  838|Homo sapiens cAMP-specific phosphodi...    91   3e-18
AY129950-1|AAN71725.1|  885|Homo sapiens cAMP-specific phosphodi...    91   3e-18
AY129949-1|AAN71724.1|  788|Homo sapiens cAMP-specific phosphodi...    91   3e-18
AY129948-1|AAN71723.1|  838|Homo sapiens cAMP-specific phosphodi...    91   3e-18
AL831924-1|CAD38584.1|  843|Homo sapiens hypothetical protein pr...    91   3e-18
AF079529-1|AAC69564.2|  885|Homo sapiens cAMP-specific phosphodi...    91   3e-18
AB085827-1|BAC53765.1|  865|Homo sapiens phosphodiesterase 8B4 p...    91   3e-18
AB085826-1|BAC53764.1|  830|Homo sapiens phosphodiesterase 8B3 p...    91   3e-18
AB085825-1|BAC53763.1|  788|Homo sapiens phosphodiestearse 8B2 p...    91   3e-18
AB085824-1|BAC53762.1|  885|Homo sapiens phosphodiesterase 8B1 p...    91   3e-18
L20968-1|AAA03591.1|  251|Homo sapiens phosphodiesterase protein.      91   4e-18
U40370-1|AAC50436.1|  535|Homo sapiens 3',5' cyclic nucleotide p...    89   1e-17
BC022480-1|AAH22480.1|  545|Homo sapiens phosphodiesterase 1A, c...    89   1e-17
AL110263-1|CAB53703.1|  519|Homo sapiens hypothetical protein pr...    89   1e-17
AJ401610-1|CAC82208.1|  519|Homo sapiens 3'5' cyclic nucleotide ...    89   1e-17
AB038224-9|BAB20054.1|  518|Homo sapiens calmodulin-dependent ph...    89   1e-17
AB038224-8|BAB20053.1|  501|Homo sapiens calmodulin-dependent ph...    89   1e-17
AB038224-7|BAB20057.1|  511|Homo sapiens calmodulin-dependent ph...    89   1e-17
AB038224-6|BAB20052.1|  552|Homo sapiens calmodulin-dependent ph...    89   1e-17
AB038224-5|BAB20050.1|  535|Homo sapiens calmodulin-dependent ph...    89   1e-17
AB038224-4|BAB20056.1|  545|Homo sapiens calmodulin-dependent ph...    89   1e-17
AB038224-3|BAB20051.1|  536|Homo sapiens calmodulin-dependent ph...    89   1e-17
AB038224-2|BAB20049.1|  519|Homo sapiens calmodulin-dependent ph...    89   1e-17
AB038224-1|BAB20055.1|  529|Homo sapiens calmodulin-dependent ph...    89   1e-17
U40372-1|AAA96961.1|  564|Homo sapiens PDE1C3 protein.                 85   3e-16
U40371-1|AAC50437.1|  634|Homo sapiens 3',5' cyclic nucleotide p...    85   3e-16
BC022525-1|AAH22525.1|  634|Homo sapiens PDE1C protein protein.        85   3e-16
BC022479-1|AAH22479.1|  634|Homo sapiens PDE1C protein protein.        85   3e-16
AK091734-1|BAC03734.1|  769|Homo sapiens (EC 3.1.4.17).  protein.      85   3e-16
AC006377-1|AAS07516.1|  591|Homo sapiens unknown protein.              85   3e-16
M94539-1|AAA58405.1|  116|Homo sapiens cyclic nucleotide phospho...    85   4e-16
AY266362-1|AAP31234.1|  102|Homo sapiens phosphodiesterase isozy...    84   5e-16
BT007016-1|AAP35662.1|  533|Homo sapiens phosphodiesterase 9A pr...    81   4e-15
BC009047-1|AAH09047.1|  533|Homo sapiens phosphodiesterase 9A pr...    81   4e-15
AY701187-1|AAV84271.1|  485|Homo sapiens phosphodiesterase PDE9A...    81   4e-15
AY242121-1|AAO88210.1|  492|Homo sapiens type 9 cGMP-specific ph...    81   4e-15
AY196314-1|AAO34700.1|  386|Homo sapiens phosphodiesterase PDE9A...    81   4e-15
AY196313-1|AAO34699.1|  386|Homo sapiens phosphodiesterase PDE9A...    81   4e-15
AY196312-1|AAO34698.1|  567|Homo sapiens phosphodiesterase PDE9A...    81   4e-15
AY196311-1|AAO34697.1|  552|Homo sapiens phosphodiesterase PDE9A...    81   4e-15
AY196310-1|AAO34696.1|  526|Homo sapiens phosphodiesterase PDE9A...    81   4e-15
AY196309-1|AAO34695.1|  376|Homo sapiens phosphodiesterase PDE9A...    81   4e-15
AY196308-1|AAO34694.1|  386|Homo sapiens phosphodiesterase PDE9A...    81   4e-15
AY196307-1|AAO34693.1|  491|Homo sapiens phosphodiesterase PDE9A...    81   4e-15
AY196306-1|AAO34692.1|  459|Homo sapiens phosphodiesterase PDE9A...    81   4e-15
AY196305-1|AAO34691.1|  376|Homo sapiens phosphodiesterase PDE9A...    81   4e-15
AY196304-1|AAO34690.1|  433|Homo sapiens phosphodiesterase PDE9A...    81   4e-15
AY196303-1|AAO34689.1|  507|Homo sapiens phosphodiesterase PDE9A...    81   4e-15
AY196302-1|AAO34688.1|  386|Homo sapiens phosphodiesterase PDE9A...    81   4e-15
AY196301-1|AAO34687.1|  386|Homo sapiens phosphodiesterase PDE9A...    81   4e-15
AY196300-1|AAO34686.1|  492|Homo sapiens phosphodiesterase PDE9A...    81   4e-15
AY196299-1|AAO34685.1|  540|Homo sapiens phosphodiesterase PDE9A...    81   4e-15
AP001747-1|BAA95552.1|  593|Homo sapiens CGMP-specific 3',5'-cyc...    81   4e-15
AF067226-1|AAC26726.1|  465|Homo sapiens cGMP phosphodiesterase ...    81   4e-15
AF067225-1|AAC26725.1|  466|Homo sapiens cGMP phosphodiesterase ...    81   4e-15
AF067224-1|AAC26724.1|  533|Homo sapiens cGMP phosphodiesterase ...    81   4e-15
AF067223-1|AAC26723.1|  593|Homo sapiens cGMP phosphodiesterase ...    81   4e-15
AF048837-1|AAC39778.1|  593|Homo sapiens cGMP-specific phosphodi...    81   4e-15
AB017602-1|BAA88847.1|  593|Homo sapiens cGMP phosphodiesterase ...    81   4e-15
U67733-1|AAC51320.1|  941|Homo sapiens PDE2A3 protein.                 73   2e-12
BC040974-1|AAH40974.1|  941|Homo sapiens phosphodiesterase 2A, c...    73   2e-12
AY495087-1|AAS75513.1|  932|Homo sapiens cGMP-stimulated phospho...    73   2e-12
AK131525-1|BAD18664.1|  685|Homo sapiens protein ( Homo sapiens ...    73   2e-12
U36798-1|AAB18673.1| 1141|Homo sapiens platelet cGI-PDE protein.       71   4e-12
M91667-1|AAA35912.2| 1141|Homo sapiens cGMP-inhibited cAMP phosp...    71   4e-12
BC117371-1|AAI17372.1| 1141|Homo sapiens phosphodiesterase 3A, c...    71   4e-12
BC117369-1|AAI17370.1| 1141|Homo sapiens phosphodiesterase 3A, c...    71   4e-12
AJ005036-1|CAA06304.1| 1141|Homo sapiens phosphodiesterase 3A pr...    71   4e-12
X95520-1|CAA64774.1| 1112|Homo sapiens cyclic nucleotide phospho...    70   1e-11
U38178-1|AAC50724.1| 1112|Homo sapiens cyclic nucleotide phophod...    70   1e-11
D50640-1|BAA09306.1| 1112|Homo sapiens phosphodiesterase 3B prot...    70   1e-11
BC150307-1|AAI50308.1| 1112|Homo sapiens phosphodiesterase 3B, c...    70   1e-11
AY459346-1|AAR24292.1| 1112|Homo sapiens cGMP-inhibited cAMP pho...    70   1e-11
EF108327-1|ABL14249.1|  502|Homo sapiens phosphodiesterase PDE7B...    67   6e-11
BC075083-1|AAH75083.1|  450|Homo sapiens phosphodiesterase 7B pr...    67   6e-11
BC075082-1|AAH75082.1|  450|Homo sapiens phosphodiesterase 7B pr...    67   6e-11
AL360178-1|CAH73075.1|  450|Homo sapiens phosphodiesterase 7B pr...    67   6e-11
AL138828-4|CAI95287.1|  450|Homo sapiens phosphodiesterase 7B pr...    67   6e-11
AL138828-3|CAI95286.1|  199|Homo sapiens phosphodiesterase 7B pr...    67   6e-11
AL133319-1|CAH73332.1|  450|Homo sapiens phosphodiesterase 7B pr...    67   6e-11
AJ251860-1|CAB92441.1|  450|Homo sapiens phosphodiesterase 7B pr...    67   6e-11
AB209990-1|BAE06072.1|  586|Homo sapiens PDE7B variant protein p...    67   6e-11
AB038040-1|BAA96537.1|  450|Homo sapiens cyclic nucleotide phosp...    67   6e-11
U67932-1|AAB65772.1|  456|Homo sapiens cAMP phosphodiesterase PD...    61   4e-09
L12052-1|AAA35644.2|  482|Homo sapiens cAMP phosphodiesterase PD...    61   4e-09
BC126360-1|AAI26361.1|  456|Homo sapiens phosphodiesterase 7A pr...    61   4e-09
AF332652-1|AAK57640.1|  424|Homo sapiens cAMP-specific cyclic nu...    61   4e-09
BC114431-1|AAI14432.1|  934|Homo sapiens phosphodiesterase 11A p...    58   5e-08
BC112393-1|AAI12394.1|  934|Homo sapiens phosphodiesterase 11A p...    58   5e-08
AJ278682-1|CAC15567.1|  684|Homo sapiens cAMP/cGMP cyclic nucleo...    58   5e-08
AJ251509-1|CAB82573.1|  490|Homo sapiens cyclic nucleotide phosp...    58   5e-08
AF281865-1|AAG32023.1|  576|Homo sapiens cAMP/cGMP phosphodieste...    58   5e-08
AB048423-3|BAB62714.1|  490|Homo sapiens phosphodiesterase 11A1 ...    58   5e-08
AB048423-2|BAB62712.1|  934|Homo sapiens phosphodiesterase 11A4 ...    58   5e-08
AB048423-1|BAB62713.2|  684|Homo sapiens phosphodiesterase 11A3 ...    58   5e-08
AB038041-1|BAB16372.1|  684|Homo sapiens phosphodiesterase 11A3 ...    58   5e-08
AB036704-1|BAB16371.1|  934|Homo sapiens phosphodiesterase 11A p...    58   5e-08
AC012499-1|AAY14803.1|  325|Homo sapiens unknown protein.              57   8e-08
X94354-1|CAA64079.1|  858|Homo sapiens cone cGMP phosphodiestera...    51   4e-06
U31973-1|AAA96392.1|  858|Homo sapiens phosphodiesterase A' subu...    51   4e-06
U20212-1|AAA92886.1|  858|Homo sapiens cone photoreceptor cGMP-p...    51   4e-06
AL356214-7|CAH72330.1|  858|Homo sapiens phosphodiesterase 6C, c...    51   4e-06
AL157396-4|CAH73839.1|  858|Homo sapiens phosphodiesterase 6C, c...    51   4e-06
M26061-1|AAB69155.1|  860|Homo sapiens PDEA protein.                   48   3e-05
BC035909-1|AAH35909.1|  860|Homo sapiens phosphodiesterase 6A, c...    48   3e-05
X90587-1|CAA62215.1|  617|Homo sapiens Rod cGMP phosphodiesteras...    46   2e-04
X66142-1|CAA46932.1|  854|Homo sapiens 3',5'-cyclic-nucleotide  ...    46   2e-04
X62692-1|CAA44569.1|  854|Homo sapiens cGMP phosphodiesterase be...    46   2e-04
S41458-1|AAB22690.1|  854|Homo sapiens rod cGMP phosphodiesteras...    46   2e-04
BT009794-1|AAP88796.1|  853|Homo sapiens phosphodiesterase 6B, c...    45   4e-04
BC000249-1|AAH00249.1|  853|Homo sapiens phosphodiesterase 6B, c...    45   4e-04
D89094-1|BAA28945.1|  875|Homo sapiens 3',5'-cyclic GMP phosphod...    43   0.001
BC126233-1|AAI26234.1|  875|Homo sapiens phosphodiesterase 5A, c...    43   0.001
AY264918-1|AAP21809.1|  833|Homo sapiens phosphodiesterase 5A pr...    43   0.001
AJ004865-1|CAA06170.1|  875|Homo sapiens cGMP-binding, cGMP-spec...    43   0.001
AF043731-1|AAC63967.1|  875|Homo sapiens cGMP-binding cGMP-speci...    43   0.001
AC093752-1|AAY40985.1|  331|Homo sapiens unknown protein.              43   0.001
AB001635-1|BAA33372.2|  875|Homo sapiens cGMP-binding cGMP-speci...    43   0.001
U86077-1|AAC51871.1|   71|Homo sapiens calmodulin-stimulated pho...    42   0.003
CR536567-1|CAG38804.1|  779|Homo sapiens PDE10A protein.               33   1.2  
BC104860-1|AAI04861.1|  779|Homo sapiens phosphodiesterase 10A p...    33   1.2  
BC104858-1|AAI04859.1|  779|Homo sapiens phosphodiesterase 10A p...    33   1.2  
AL160160-1|CAH72023.1|  779|Homo sapiens phosphodiesterase 10A p...    33   1.2  
AL136130-1|CAI20436.1|  779|Homo sapiens phosphodiesterase 10A p...    33   1.2  
AL117345-1|CAB92797.2|  779|Homo sapiens phosphodiesterase 10A p...    33   1.2  
AL109778-1|CAB52432.1|  178|Homo sapiens PDE8A; phosphodiesteras...    33   1.2  
AL109687-1|CAB52020.1|  160|Homo sapiens PDE8A; phosphodiesteras...    33   1.2  
AF127480-1|AAD32596.1|  807|Homo sapiens 3',5'-cyclic nucleotide...    33   1.2  
AF127479-1|AAD32595.1|  779|Homo sapiens 3',5'-cyclic nucleotide...    33   1.2  
AB041798-3|BAB16383.1|  714|Homo sapiens phosphodiesterase 10A1 ...    33   1.2  
AB026816-1|BAA84467.1|  789|Homo sapiens 3',5'-cyclic nucleotide...    33   1.2  
AB020593-1|BAA78034.1|  779|Homo sapiens 3',5'-Cyclic nucleotide...    33   1.2  
Y10260-1|CAA71309.1|  559|Homo sapiens EYA1A protein.                  31   6.3  
BC121799-1|AAI21800.1|  592|Homo sapiens eyes absent homolog 1 (...    31   6.3  
BC121798-1|AAI21799.1|  519|Homo sapiens EYA1 protein protein.         31   6.3  
AK057294-1|BAB71413.1|  766|Homo sapiens protein ( Homo sapiens ...    31   6.3  
AJ000098-1|CAA03923.1|  592|Homo sapiens EYA1C protein.                31   6.3  
AJ000097-1|CAA03922.1|  592|Homo sapiens EYA1B protein.                31   6.3  
AF467247-1|AAL73437.1|  557|Homo sapiens EYA1D protein.                31   6.3  
AB002363-1|BAA20820.2| 1181|Homo sapiens KIAA0365 protein protein.     30   8.3  

>U85048-1|AAB96381.1|  721|Homo sapiens cyclic AMP specific
           phosphodiesterase protein.
          Length = 721

 Score =  159 bits (385), Expect = 1e-38
 Identities = 74/88 (84%), Positives = 83/88 (94%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ + CDIF+NL KKQRQTLRKM
Sbjct: 435 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKM 494

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHMSLLADLKTMVE +K
Sbjct: 495 VIDMVLATDMSKHMSLLADLKTMVETKK 522



 Score =  110 bits (265), Expect = 5e-24
 Identities = 50/85 (58%), Positives = 65/85 (76%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL T +I + TF+ + +TLE+HY  D  +HNSLHAADV QST+VLL+T
Sbjct: 350 TCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLST 409

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AA+FAA +HDVD
Sbjct: 410 PALDAVFTDLEILAAIFAAAIHDVD 434



 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 36/44 (81%), Positives = 39/44 (88%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W
Sbjct: 520 TKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQW 563



 Score = 66.9 bits (156), Expect = 8e-11
 Identities = 26/39 (66%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GD+ERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 574 QGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 612


>M97515-1|AAA36426.1|  564|Homo sapiens phosphodiesterase protein.
          Length = 564

 Score =  159 bits (385), Expect = 1e-38
 Identities = 74/88 (84%), Positives = 83/88 (94%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ + CDIF+NL KKQRQTLRKM
Sbjct: 278 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKM 337

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHMSLLADLKTMVE +K
Sbjct: 338 VIDMVLATDMSKHMSLLADLKTMVETKK 365



 Score =  110 bits (265), Expect = 5e-24
 Identities = 50/85 (58%), Positives = 65/85 (76%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL T +I + TF+ + +TLE+HY  D  +HNSLHAADV QST+VLL+T
Sbjct: 193 TCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLST 252

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AA+FAA +HDVD
Sbjct: 253 PALDAVFTDLEILAAIFAAAIHDVD 277



 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 36/44 (81%), Positives = 39/44 (88%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W
Sbjct: 363 TKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQW 406



 Score = 66.9 bits (156), Expect = 8e-11
 Identities = 26/39 (66%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GD+ERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 417 QGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 455


>L20971-1|AAA03593.1|  564|Homo sapiens phosphodiesterase protein.
          Length = 564

 Score =  159 bits (385), Expect = 1e-38
 Identities = 74/88 (84%), Positives = 83/88 (94%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ + CDIF+NL KKQRQTLRKM
Sbjct: 278 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKM 337

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHMSLLADLKTMVE +K
Sbjct: 338 VIDMVLATDMSKHMSLLADLKTMVETKK 365



 Score =  110 bits (265), Expect = 5e-24
 Identities = 50/85 (58%), Positives = 65/85 (76%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL T +I + TF+ + +TLE+HY  D  +HNSLHAADV QST+VLL+T
Sbjct: 193 TCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLST 252

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AA+FAA +HDVD
Sbjct: 253 PALDAVFTDLEILAAIFAAAIHDVD 277



 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 36/44 (81%), Positives = 39/44 (88%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W
Sbjct: 363 TKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQW 406



 Score = 66.9 bits (156), Expect = 8e-11
 Identities = 26/39 (66%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GD+ERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 417 QGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 455


>L20966-1|AAA03589.1|  736|Homo sapiens phosphodiesterase protein.
          Length = 736

 Score =  159 bits (385), Expect = 1e-38
 Identities = 74/88 (84%), Positives = 83/88 (94%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ + CDIF+NL KKQRQTLRKM
Sbjct: 450 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKM 509

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHMSLLADLKTMVE +K
Sbjct: 510 VIDMVLATDMSKHMSLLADLKTMVETKK 537



 Score =  110 bits (265), Expect = 5e-24
 Identities = 50/85 (58%), Positives = 65/85 (76%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL T +I + TF+ + +TLE+HY  D  +HNSLHAADV QST+VLL+T
Sbjct: 365 TCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLST 424

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AA+FAA +HDVD
Sbjct: 425 PALDAVFTDLEILAAIFAAAIHDVD 449



 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 36/44 (81%), Positives = 39/44 (88%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W
Sbjct: 535 TKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQW 578



 Score = 66.9 bits (156), Expect = 8e-11
 Identities = 26/39 (66%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GD+ERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 589 QGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 627


>L12686-1|AAA35643.1|  606|Homo sapiens 3',5'-cyclic AMP
           phosphodiesterase protein.
          Length = 606

 Score =  159 bits (385), Expect = 1e-38
 Identities = 74/88 (84%), Positives = 83/88 (94%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ + CDIF+NL KKQRQTLRKM
Sbjct: 320 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKM 379

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHMSLLADLKTMVE +K
Sbjct: 380 VIDMVLATDMSKHMSLLADLKTMVETKK 407



 Score =  110 bits (265), Expect = 5e-24
 Identities = 50/85 (58%), Positives = 65/85 (76%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL T +I + TF+ + +TLE+HY  D  +HNSLHAADV QST+VLL+T
Sbjct: 235 TCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLST 294

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AA+FAA +HDVD
Sbjct: 295 PALDAVFTDLEILAAIFAAAIHDVD 319



 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 36/44 (81%), Positives = 39/44 (88%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W
Sbjct: 405 TKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQW 448



 Score = 66.9 bits (156), Expect = 8e-11
 Identities = 26/39 (66%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GD+ERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 459 QGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 497


>EF595686-1|ABQ85407.1|  503|Homo sapiens cAMP-specific
           phosphodiesterase-4 B isoform protein.
          Length = 503

 Score =  159 bits (385), Expect = 1e-38
 Identities = 74/88 (84%), Positives = 83/88 (94%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ + CDIF+NL KKQRQTLRKM
Sbjct: 217 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKM 276

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHMSLLADLKTMVE +K
Sbjct: 277 VIDMVLATDMSKHMSLLADLKTMVETKK 304



 Score =  110 bits (265), Expect = 5e-24
 Identities = 50/85 (58%), Positives = 65/85 (76%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL T +I + TF+ + +TLE+HY  D  +HNSLHAADV QST+VLL+T
Sbjct: 132 TCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLST 191

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AA+FAA +HDVD
Sbjct: 192 PALDAVFTDLEILAAIFAAAIHDVD 216



 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 36/44 (81%), Positives = 39/44 (88%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W
Sbjct: 302 TKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQW 345



 Score = 66.9 bits (156), Expect = 8e-11
 Identities = 26/39 (66%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GD+ERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 356 QGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 394


>BC105040-1|AAI05041.1|  736|Homo sapiens phosphodiesterase 4B,
           cAMP-specific (phosphodiesterase E4 dunce homolog,
           Drosop protein.
          Length = 736

 Score =  159 bits (385), Expect = 1e-38
 Identities = 74/88 (84%), Positives = 83/88 (94%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ + CDIF+NL KKQRQTLRKM
Sbjct: 450 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKM 509

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHMSLLADLKTMVE +K
Sbjct: 510 VIDMVLATDMSKHMSLLADLKTMVETKK 537



 Score =  110 bits (265), Expect = 5e-24
 Identities = 50/85 (58%), Positives = 65/85 (76%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL T +I + TF+ + +TLE+HY  D  +HNSLHAADV QST+VLL+T
Sbjct: 365 TCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLST 424

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AA+FAA +HDVD
Sbjct: 425 PALDAVFTDLEILAAIFAAAIHDVD 449



 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 36/44 (81%), Positives = 39/44 (88%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W
Sbjct: 535 TKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQW 578



 Score = 66.9 bits (156), Expect = 8e-11
 Identities = 26/39 (66%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GD+ERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 589 QGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 627


>BC101480-1|AAI01481.1|  736|Homo sapiens phosphodiesterase 4B,
           cAMP-specific (phosphodiesterase E4 dunce homolog,
           Drosop protein.
          Length = 736

 Score =  159 bits (385), Expect = 1e-38
 Identities = 74/88 (84%), Positives = 83/88 (94%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ + CDIF+NL KKQRQTLRKM
Sbjct: 450 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKM 509

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHMSLLADLKTMVE +K
Sbjct: 510 VIDMVLATDMSKHMSLLADLKTMVETKK 537



 Score =  110 bits (265), Expect = 5e-24
 Identities = 50/85 (58%), Positives = 65/85 (76%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL T +I + TF+ + +TLE+HY  D  +HNSLHAADV QST+VLL+T
Sbjct: 365 TCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLST 424

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AA+FAA +HDVD
Sbjct: 425 PALDAVFTDLEILAAIFAAAIHDVD 449



 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 36/44 (81%), Positives = 39/44 (88%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W
Sbjct: 535 TKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQW 578



 Score = 66.9 bits (156), Expect = 8e-11
 Identities = 26/39 (66%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GD+ERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 589 QGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 627


>AL592285-3|CAH70628.1|  721|Homo sapiens phosphodiesterase 4B,
           cAMP-specific (phosphodiesterase E4 dunce homolog,
           Drosop protein.
          Length = 721

 Score =  159 bits (385), Expect = 1e-38
 Identities = 74/88 (84%), Positives = 83/88 (94%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ + CDIF+NL KKQRQTLRKM
Sbjct: 435 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKM 494

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHMSLLADLKTMVE +K
Sbjct: 495 VIDMVLATDMSKHMSLLADLKTMVETKK 522



 Score =  110 bits (265), Expect = 5e-24
 Identities = 50/85 (58%), Positives = 65/85 (76%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL T +I + TF+ + +TLE+HY  D  +HNSLHAADV QST+VLL+T
Sbjct: 350 TCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLST 409

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AA+FAA +HDVD
Sbjct: 410 PALDAVFTDLEILAAIFAAAIHDVD 434



 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 36/44 (81%), Positives = 39/44 (88%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W
Sbjct: 520 TKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQW 563



 Score = 66.9 bits (156), Expect = 8e-11
 Identities = 26/39 (66%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GD+ERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 574 QGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 612


>AL592285-1|CAH70626.1|  736|Homo sapiens phosphodiesterase 4B,
           cAMP-specific (phosphodiesterase E4 dunce homolog,
           Drosop protein.
          Length = 736

 Score =  159 bits (385), Expect = 1e-38
 Identities = 74/88 (84%), Positives = 83/88 (94%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ + CDIF+NL KKQRQTLRKM
Sbjct: 450 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKM 509

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHMSLLADLKTMVE +K
Sbjct: 510 VIDMVLATDMSKHMSLLADLKTMVETKK 537



 Score =  110 bits (265), Expect = 5e-24
 Identities = 50/85 (58%), Positives = 65/85 (76%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL T +I + TF+ + +TLE+HY  D  +HNSLHAADV QST+VLL+T
Sbjct: 365 TCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLST 424

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AA+FAA +HDVD
Sbjct: 425 PALDAVFTDLEILAAIFAAAIHDVD 449



 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 36/44 (81%), Positives = 39/44 (88%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W
Sbjct: 535 TKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQW 578



 Score = 66.9 bits (156), Expect = 8e-11
 Identities = 26/39 (66%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GD+ERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 589 QGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 627


>AL359701-3|CAI23101.1|  721|Homo sapiens phosphodiesterase 4B,
           cAMP-specific (phosphodiesterase E4 dunce homolog,
           Drosop protein.
          Length = 721

 Score =  159 bits (385), Expect = 1e-38
 Identities = 74/88 (84%), Positives = 83/88 (94%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ + CDIF+NL KKQRQTLRKM
Sbjct: 435 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKM 494

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHMSLLADLKTMVE +K
Sbjct: 495 VIDMVLATDMSKHMSLLADLKTMVETKK 522



 Score =  110 bits (265), Expect = 5e-24
 Identities = 50/85 (58%), Positives = 65/85 (76%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL T +I + TF+ + +TLE+HY  D  +HNSLHAADV QST+VLL+T
Sbjct: 350 TCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLST 409

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AA+FAA +HDVD
Sbjct: 410 PALDAVFTDLEILAAIFAAAIHDVD 434



 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 36/44 (81%), Positives = 39/44 (88%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W
Sbjct: 520 TKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQW 563



 Score = 66.9 bits (156), Expect = 8e-11
 Identities = 26/39 (66%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GD+ERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 574 QGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 612


>AL359701-2|CAI23100.1|  564|Homo sapiens phosphodiesterase 4B,
           cAMP-specific (phosphodiesterase E4 dunce homolog,
           Drosop protein.
          Length = 564

 Score =  159 bits (385), Expect = 1e-38
 Identities = 74/88 (84%), Positives = 83/88 (94%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ + CDIF+NL KKQRQTLRKM
Sbjct: 278 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKM 337

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHMSLLADLKTMVE +K
Sbjct: 338 VIDMVLATDMSKHMSLLADLKTMVETKK 365



 Score =  110 bits (265), Expect = 5e-24
 Identities = 50/85 (58%), Positives = 65/85 (76%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL T +I + TF+ + +TLE+HY  D  +HNSLHAADV QST+VLL+T
Sbjct: 193 TCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLST 252

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AA+FAA +HDVD
Sbjct: 253 PALDAVFTDLEILAAIFAAAIHDVD 277



 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 36/44 (81%), Positives = 39/44 (88%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W
Sbjct: 363 TKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQW 406



 Score = 66.9 bits (156), Expect = 8e-11
 Identities = 26/39 (66%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GD+ERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 417 QGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 455


>AL359701-1|CAI23099.1|  736|Homo sapiens phosphodiesterase 4B,
           cAMP-specific (phosphodiesterase E4 dunce homolog,
           Drosop protein.
          Length = 736

 Score =  159 bits (385), Expect = 1e-38
 Identities = 74/88 (84%), Positives = 83/88 (94%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ + CDIF+NL KKQRQTLRKM
Sbjct: 450 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKM 509

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHMSLLADLKTMVE +K
Sbjct: 510 VIDMVLATDMSKHMSLLADLKTMVETKK 537



 Score =  110 bits (265), Expect = 5e-24
 Identities = 50/85 (58%), Positives = 65/85 (76%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL T +I + TF+ + +TLE+HY  D  +HNSLHAADV QST+VLL+T
Sbjct: 365 TCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLST 424

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AA+FAA +HDVD
Sbjct: 425 PALDAVFTDLEILAAIFAAAIHDVD 449



 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 36/44 (81%), Positives = 39/44 (88%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W
Sbjct: 535 TKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQW 578



 Score = 66.9 bits (156), Expect = 8e-11
 Identities = 26/39 (66%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GD+ERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 589 QGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 627


>AL357273-3|CAH73004.1|  721|Homo sapiens phosphodiesterase 4B,
           cAMP-specific (phosphodiesterase E4 dunce homolog,
           Drosop protein.
          Length = 721

 Score =  159 bits (385), Expect = 1e-38
 Identities = 74/88 (84%), Positives = 83/88 (94%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ + CDIF+NL KKQRQTLRKM
Sbjct: 435 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKM 494

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHMSLLADLKTMVE +K
Sbjct: 495 VIDMVLATDMSKHMSLLADLKTMVETKK 522



 Score =  110 bits (265), Expect = 5e-24
 Identities = 50/85 (58%), Positives = 65/85 (76%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL T +I + TF+ + +TLE+HY  D  +HNSLHAADV QST+VLL+T
Sbjct: 350 TCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLST 409

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AA+FAA +HDVD
Sbjct: 410 PALDAVFTDLEILAAIFAAAIHDVD 434



 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 36/44 (81%), Positives = 39/44 (88%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W
Sbjct: 520 TKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQW 563



 Score = 66.9 bits (156), Expect = 8e-11
 Identities = 26/39 (66%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GD+ERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 574 QGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 612


>AL357273-1|CAH73002.1|  736|Homo sapiens phosphodiesterase 4B,
           cAMP-specific (phosphodiesterase E4 dunce homolog,
           Drosop protein.
          Length = 736

 Score =  159 bits (385), Expect = 1e-38
 Identities = 74/88 (84%), Positives = 83/88 (94%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ + CDIF+NL KKQRQTLRKM
Sbjct: 450 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKM 509

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHMSLLADLKTMVE +K
Sbjct: 510 VIDMVLATDMSKHMSLLADLKTMVETKK 537



 Score =  110 bits (265), Expect = 5e-24
 Identities = 50/85 (58%), Positives = 65/85 (76%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL T +I + TF+ + +TLE+HY  D  +HNSLHAADV QST+VLL+T
Sbjct: 365 TCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLST 424

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AA+FAA +HDVD
Sbjct: 425 PALDAVFTDLEILAAIFAAAIHDVD 449



 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 36/44 (81%), Positives = 39/44 (88%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W
Sbjct: 535 TKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQW 578



 Score = 66.9 bits (156), Expect = 8e-11
 Identities = 26/39 (66%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GD+ERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 589 QGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 627


>AL109926-4|CAI21751.1|  721|Homo sapiens phosphodiesterase 4B,
           cAMP-specific (phosphodiesterase E4 dunce homolog,
           Drosop protein.
          Length = 721

 Score =  159 bits (385), Expect = 1e-38
 Identities = 74/88 (84%), Positives = 83/88 (94%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ + CDIF+NL KKQRQTLRKM
Sbjct: 435 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKM 494

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHMSLLADLKTMVE +K
Sbjct: 495 VIDMVLATDMSKHMSLLADLKTMVETKK 522



 Score =  110 bits (265), Expect = 5e-24
 Identities = 50/85 (58%), Positives = 65/85 (76%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL T +I + TF+ + +TLE+HY  D  +HNSLHAADV QST+VLL+T
Sbjct: 350 TCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLST 409

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AA+FAA +HDVD
Sbjct: 410 PALDAVFTDLEILAAIFAAAIHDVD 434



 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 36/44 (81%), Positives = 39/44 (88%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W
Sbjct: 520 TKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQW 563



 Score = 66.9 bits (156), Expect = 8e-11
 Identities = 26/39 (66%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GD+ERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 574 QGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 612


>AL109926-3|CAI21750.1|  564|Homo sapiens phosphodiesterase 4B,
           cAMP-specific (phosphodiesterase E4 dunce homolog,
           Drosop protein.
          Length = 564

 Score =  159 bits (385), Expect = 1e-38
 Identities = 74/88 (84%), Positives = 83/88 (94%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ + CDIF+NL KKQRQTLRKM
Sbjct: 278 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKM 337

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHMSLLADLKTMVE +K
Sbjct: 338 VIDMVLATDMSKHMSLLADLKTMVETKK 365



 Score =  110 bits (265), Expect = 5e-24
 Identities = 50/85 (58%), Positives = 65/85 (76%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL T +I + TF+ + +TLE+HY  D  +HNSLHAADV QST+VLL+T
Sbjct: 193 TCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLST 252

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AA+FAA +HDVD
Sbjct: 253 PALDAVFTDLEILAAIFAAAIHDVD 277



 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 36/44 (81%), Positives = 39/44 (88%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W
Sbjct: 363 TKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQW 406



 Score = 66.9 bits (156), Expect = 8e-11
 Identities = 26/39 (66%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GD+ERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 417 QGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 455


>AL109926-2|CAI21749.1|  736|Homo sapiens phosphodiesterase 4B,
           cAMP-specific (phosphodiesterase E4 dunce homolog,
           Drosop protein.
          Length = 736

 Score =  159 bits (385), Expect = 1e-38
 Identities = 74/88 (84%), Positives = 83/88 (94%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ + CDIF+NL KKQRQTLRKM
Sbjct: 450 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKM 509

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHMSLLADLKTMVE +K
Sbjct: 510 VIDMVLATDMSKHMSLLADLKTMVETKK 537



 Score =  110 bits (265), Expect = 5e-24
 Identities = 50/85 (58%), Positives = 65/85 (76%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL T +I + TF+ + +TLE+HY  D  +HNSLHAADV QST+VLL+T
Sbjct: 365 TCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLST 424

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AA+FAA +HDVD
Sbjct: 425 PALDAVFTDLEILAAIFAAAIHDVD 449



 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 36/44 (81%), Positives = 39/44 (88%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W
Sbjct: 535 TKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQW 578



 Score = 66.9 bits (156), Expect = 8e-11
 Identities = 26/39 (66%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GD+ERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 589 QGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 627


>AB209081-1|BAD92318.1|  726|Homo sapiens phosphodiesterase 4B,
           cAMP-specific (phosphodiesterase E4 dunce homolog,
           Drosop protein.
          Length = 726

 Score =  159 bits (385), Expect = 1e-38
 Identities = 74/88 (84%), Positives = 83/88 (94%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ + CDIF+NL KKQRQTLRKM
Sbjct: 440 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKM 499

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHMSLLADLKTMVE +K
Sbjct: 500 VIDMVLATDMSKHMSLLADLKTMVETKK 527



 Score =  110 bits (265), Expect = 5e-24
 Identities = 50/85 (58%), Positives = 65/85 (76%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL T +I + TF+ + +TLE+HY  D  +HNSLHAADV QST+VLL+T
Sbjct: 355 TCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLST 414

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AA+FAA +HDVD
Sbjct: 415 PALDAVFTDLEILAAIFAAAIHDVD 439



 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 36/44 (81%), Positives = 39/44 (88%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W
Sbjct: 525 TKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQW 568



 Score = 66.9 bits (156), Expect = 8e-11
 Identities = 26/39 (66%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GD+ERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 579 QGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 617


>U97584-1|AAC25679.1|  647|Homo sapiens cyclic AMP-specific
           phosphodiesterase HSPDE4A1A protein.
          Length = 647

 Score =  156 bits (379), Expect = 7e-38
 Identities = 72/88 (81%), Positives = 82/88 (93%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ D CDIF NL K+QRQ+LRKM
Sbjct: 238 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKM 297

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 298 VIDMVLATDMSKHMTLLADLKTMVETKK 325



 Score =  107 bits (256), Expect = 6e-23
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL   +IP  T + + +TLE+HY  D  +HNSLHAADV QST+VLL T
Sbjct: 153 TCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLAT 212

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AALFAA +HDVD
Sbjct: 213 PALDAVFTDLEILAALFAAAIHDVD 237



 Score = 84.2 bits (199), Expect = 5e-16
 Identities = 45/86 (52%), Positives = 52/86 (60%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV  SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W   +            
Sbjct: 323 TKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRER 382

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
                IS  C       +EKSQVG +
Sbjct: 383 ERGMEISPMC-DKHTASVEKSQVGFI 407



 Score = 68.1 bits (159), Expect = 3e-11
 Identities = 27/39 (69%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 377 QGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 415


>U68532-1|AAC63832.1|  647|Homo sapiens cyclic AMP specific
           phosphodiesterase RD1 protein.
          Length = 647

 Score =  156 bits (379), Expect = 7e-38
 Identities = 72/88 (81%), Positives = 82/88 (93%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ D CDIF NL K+QRQ+LRKM
Sbjct: 238 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKM 297

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 298 VIDMVLATDMSKHMTLLADLKTMVETKK 325



 Score =  107 bits (256), Expect = 6e-23
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL   +IP  T + + +TLE+HY  D  +HNSLHAADV QST+VLL T
Sbjct: 153 TCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLAT 212

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AALFAA +HDVD
Sbjct: 213 PALDAVFTDLEILAALFAAAIHDVD 237



 Score = 84.2 bits (199), Expect = 5e-16
 Identities = 45/86 (52%), Positives = 52/86 (60%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV  SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W   +            
Sbjct: 323 TKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRER 382

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
                IS  C       +EKSQVG +
Sbjct: 383 ERGMEISPMC-DKHTASVEKSQVGFI 407



 Score = 68.1 bits (159), Expect = 3e-11
 Identities = 27/39 (69%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 377 QGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 415


>U18088-1|AAA98540.1|  323|Homo sapiens 3',5'-cyclic AMP
           phosphodiesterase HSPDE4A7A protein.
          Length = 323

 Score =  156 bits (379), Expect = 7e-38
 Identities = 72/88 (81%), Positives = 82/88 (93%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ D CDIF NL K+QRQ+LRKM
Sbjct: 143 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKM 202

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 203 VIDMVLATDMSKHMTLLADLKTMVETKK 230



 Score =  107 bits (256), Expect = 6e-23
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL   +IP  T + + +TLE+HY  D  +HNSLHAADV QST+VLL T
Sbjct: 58  TCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLAT 117

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AALFAA +HDVD
Sbjct: 118 PALDAVFTDLEILAALFAAAIHDVD 142



 Score = 83.8 bits (198), Expect = 6e-16
 Identities = 36/44 (81%), Positives = 40/44 (90%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W
Sbjct: 228 TKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQW 271



 Score = 47.2 bits (107), Expect = 7e-05
 Identities = 20/34 (58%), Positives = 27/34 (79%), Gaps = 2/34 (5%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRK--ISSRFID 768
           +GDRERE GM+ISPMCD+H A++ K  + +R ID
Sbjct: 282 QGDRERERGMEISPMCDKHTASVEKSQVQARGID 315


>U18087-1|AAC50458.1|  686|Homo sapiens 3',5'-cyclic AMP
           phosphodiesterase HPDE4A6 protein.
          Length = 686

 Score =  156 bits (379), Expect = 7e-38
 Identities = 72/88 (81%), Positives = 82/88 (93%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ D CDIF NL K+QRQ+LRKM
Sbjct: 277 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKM 336

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 337 VIDMVLATDMSKHMTLLADLKTMVETKK 364



 Score =  107 bits (256), Expect = 6e-23
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL   +IP  T + + +TLE+HY  D  +HNSLHAADV QST+VLL T
Sbjct: 192 TCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLAT 251

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AALFAA +HDVD
Sbjct: 252 PALDAVFTDLEILAALFAAAIHDVD 276



 Score = 84.2 bits (199), Expect = 5e-16
 Identities = 45/86 (52%), Positives = 52/86 (60%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV  SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W   +            
Sbjct: 362 TKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRER 421

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
                IS  C       +EKSQVG +
Sbjct: 422 ERGMEISPMC-DKHTASVEKSQVGFI 446



 Score = 68.1 bits (159), Expect = 3e-11
 Identities = 27/39 (69%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 416 QGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 454


>S75213-1|AAB33798.1|  667|Homo sapiens type-IVA cyclic AMP specific
           phosphodiesterase protein.
          Length = 667

 Score =  156 bits (379), Expect = 7e-38
 Identities = 72/88 (81%), Positives = 82/88 (93%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ D CDIF NL K+QRQ+LRKM
Sbjct: 258 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKM 317

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 318 VIDMVLATDMSKHMTLLADLKTMVETKK 345



 Score =  107 bits (256), Expect = 6e-23
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL   +IP  T + + +TLE+HY  D  +HNSLHAADV QST+VLL T
Sbjct: 173 TCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLAT 232

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AALFAA +HDVD
Sbjct: 233 PALDAVFTDLEILAALFAAAIHDVD 257



 Score = 84.2 bits (199), Expect = 5e-16
 Identities = 45/86 (52%), Positives = 52/86 (60%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV  SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W   +            
Sbjct: 343 TKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRER 402

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
                IS  C       +EKSQVG +
Sbjct: 403 ERGMEISPMC-DKHTASVEKSQVGFI 427



 Score = 68.1 bits (159), Expect = 3e-11
 Identities = 27/39 (69%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 397 QGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 435


>M37744-1|AAA69697.1|  775|Homo sapiens protein ( Human cyclic AMP
           (cAMP)-specific phosphodiesterase mRNA, complete cds. ).
          Length = 775

 Score =  156 bits (379), Expect = 7e-38
 Identities = 72/88 (81%), Positives = 82/88 (93%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ D CDIF NL K+QRQ+LRKM
Sbjct: 366 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKM 425

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 426 VIDMVLATDMSKHMTLLADLKTMVETKK 453



 Score =  107 bits (256), Expect = 6e-23
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL   +IP  T + + +TLE+HY  D  +HNSLHAADV QST+VLL T
Sbjct: 281 TCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLAT 340

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AALFAA +HDVD
Sbjct: 341 PALDAVFTDLEILAALFAAAIHDVD 365



 Score = 84.2 bits (199), Expect = 5e-16
 Identities = 45/86 (52%), Positives = 52/86 (60%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV  SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W   +            
Sbjct: 451 TKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRER 510

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
                IS  C       +EKSQVG +
Sbjct: 511 ERGMEISPMC-DKHTASVEKSQVGFI 535



 Score = 68.1 bits (159), Expect = 3e-11
 Identities = 27/39 (69%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 505 QGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 543


>L20965-1|AAA03588.1|  886|Homo sapiens phosphodiesterase protein.
          Length = 886

 Score =  156 bits (379), Expect = 7e-38
 Identities = 72/88 (81%), Positives = 82/88 (93%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ D CDIF NL K+QRQ+LRKM
Sbjct: 477 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKM 536

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 537 VIDMVLATDMSKHMTLLADLKTMVETKK 564



 Score =  107 bits (256), Expect = 6e-23
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL   +IP  T + + +TLE+HY  D  +HNSLHAADV QST+VLL T
Sbjct: 392 TCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLAT 451

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AALFAA +HDVD
Sbjct: 452 PALDAVFTDLEILAALFAAAIHDVD 476



 Score = 84.2 bits (199), Expect = 5e-16
 Identities = 45/86 (52%), Positives = 52/86 (60%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV  SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W   +            
Sbjct: 562 TKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRER 621

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
                IS  C       +EKSQVG +
Sbjct: 622 ERGMEISPMC-DKHTASVEKSQVGFI 646



 Score = 68.1 bits (159), Expect = 3e-11
 Identities = 27/39 (69%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 616 QGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 654


>BC038234-1|AAH38234.1|  647|Homo sapiens phosphodiesterase 4A,
           cAMP-specific (phosphodiesterase E2 dunce homolog,
           Drosop protein.
          Length = 647

 Score =  156 bits (379), Expect = 7e-38
 Identities = 72/88 (81%), Positives = 82/88 (93%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ D CDIF NL K+QRQ+LRKM
Sbjct: 238 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKM 297

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 298 VIDMVLATDMSKHMTLLADLKTMVETKK 325



 Score =  107 bits (256), Expect = 6e-23
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL   +IP  T + + +TLE+HY  D  +HNSLHAADV QST+VLL T
Sbjct: 153 TCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLAT 212

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AALFAA +HDVD
Sbjct: 213 PALDAVFTDLEILAALFAAAIHDVD 237



 Score = 84.2 bits (199), Expect = 5e-16
 Identities = 45/86 (52%), Positives = 52/86 (60%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV  SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W   +            
Sbjct: 323 TKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRER 382

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
                IS  C       +EKSQVG +
Sbjct: 383 ERGMEISPMC-DKHTASVEKSQVGFI 407



 Score = 68.1 bits (159), Expect = 3e-11
 Identities = 27/39 (69%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 377 QGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 415


>BC019864-1|AAH19864.1|  647|Homo sapiens phosphodiesterase 4A,
           cAMP-specific (phosphodiesterase E2 dunce homolog,
           Drosop protein.
          Length = 647

 Score =  156 bits (379), Expect = 7e-38
 Identities = 72/88 (81%), Positives = 82/88 (93%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ D CDIF NL K+QRQ+LRKM
Sbjct: 238 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKM 297

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 298 VIDMVLATDMSKHMTLLADLKTMVETKK 325



 Score =  107 bits (256), Expect = 6e-23
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL   +IP  T + + +TLE+HY  D  +HNSLHAADV QST+VLL T
Sbjct: 153 TCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLAT 212

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AALFAA +HDVD
Sbjct: 213 PALDAVFTDLEILAALFAAAIHDVD 237



 Score = 84.2 bits (199), Expect = 5e-16
 Identities = 45/86 (52%), Positives = 52/86 (60%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV  SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W   +            
Sbjct: 323 TKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRER 382

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
                IS  C       +EKSQVG +
Sbjct: 383 ERGMEISPMC-DKHTASVEKSQVGFI 407



 Score = 68.1 bits (159), Expect = 3e-11
 Identities = 27/39 (69%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 377 QGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 415


>AY618547-1|AAU82096.1|  860|Homo sapiens cyclic AMP
           phosphodiesterase PDE4A11 protein.
          Length = 860

 Score =  156 bits (379), Expect = 7e-38
 Identities = 72/88 (81%), Positives = 82/88 (93%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ D CDIF NL K+QRQ+LRKM
Sbjct: 451 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKM 510

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 511 VIDMVLATDMSKHMTLLADLKTMVETKK 538



 Score =  107 bits (256), Expect = 6e-23
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL   +IP  T + + +TLE+HY  D  +HNSLHAADV QST+VLL T
Sbjct: 366 TCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLAT 425

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AALFAA +HDVD
Sbjct: 426 PALDAVFTDLEILAALFAAAIHDVD 450



 Score = 84.2 bits (199), Expect = 5e-16
 Identities = 45/86 (52%), Positives = 52/86 (60%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV  SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W   +            
Sbjct: 536 TKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRER 595

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
                IS  C       +EKSQVG +
Sbjct: 596 ERGMEISPMC-DKHTASVEKSQVGFI 620



 Score = 68.1 bits (159), Expect = 3e-11
 Identities = 27/39 (69%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 590 QGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 628


>AY593872-1|AAT00628.1|  864|Homo sapiens cAMP-specific
           phosphodiesterase protein.
          Length = 864

 Score =  156 bits (379), Expect = 7e-38
 Identities = 72/88 (81%), Positives = 82/88 (93%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ D CDIF NL K+QRQ+LRKM
Sbjct: 455 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKM 514

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 515 VIDMVLATDMSKHMTLLADLKTMVETKK 542



 Score =  107 bits (256), Expect = 6e-23
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL   +IP  T + + +TLE+HY  D  +HNSLHAADV QST+VLL T
Sbjct: 370 TCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLAT 429

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AALFAA +HDVD
Sbjct: 430 PALDAVFTDLEILAALFAAAIHDVD 454



 Score = 84.2 bits (199), Expect = 5e-16
 Identities = 45/86 (52%), Positives = 52/86 (60%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV  SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W   +            
Sbjct: 540 TKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRER 599

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
                IS  C       +EKSQVG +
Sbjct: 600 ERGMEISPMC-DKHTASVEKSQVGFI 624



 Score = 68.1 bits (159), Expect = 3e-11
 Identities = 27/39 (69%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 594 QGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 632


>AF073745-1|AAD34217.2|  825|Homo sapiens cyclic AMP-specific
           phosphodiesterase HSPDE4A10 protein.
          Length = 825

 Score =  156 bits (379), Expect = 7e-38
 Identities = 72/88 (81%), Positives = 82/88 (93%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ D CDIF NL K+QRQ+LRKM
Sbjct: 416 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKM 475

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 476 VIDMVLATDMSKHMTLLADLKTMVETKK 503



 Score =  107 bits (256), Expect = 6e-23
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL   +IP  T + + +TLE+HY  D  +HNSLHAADV QST+VLL T
Sbjct: 331 TCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLAT 390

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AALFAA +HDVD
Sbjct: 391 PALDAVFTDLEILAALFAAAIHDVD 415



 Score = 84.2 bits (199), Expect = 5e-16
 Identities = 45/86 (52%), Positives = 52/86 (60%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV  SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W   +            
Sbjct: 501 TKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRER 560

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
                IS  C       +EKSQVG +
Sbjct: 561 ERGMEISPMC-DKHTASVEKSQVGFI 585



 Score = 68.1 bits (159), Expect = 3e-11
 Identities = 27/39 (69%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 555 QGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 593


>AF069491-4|AAC35014.1|  323|Homo sapiens cAMP specific
           phosphodiesterase 4A variant 2EL protein.
          Length = 323

 Score =  156 bits (379), Expect = 7e-38
 Identities = 72/88 (81%), Positives = 82/88 (93%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ D CDIF NL K+QRQ+LRKM
Sbjct: 143 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKM 202

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 203 VIDMVLATDMSKHMTLLADLKTMVETKK 230



 Score =  107 bits (256), Expect = 6e-23
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL   +IP  T + + +TLE+HY  D  +HNSLHAADV QST+VLL T
Sbjct: 58  TCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLAT 117

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AALFAA +HDVD
Sbjct: 118 PALDAVFTDLEILAALFAAAIHDVD 142



 Score = 83.8 bits (198), Expect = 6e-16
 Identities = 36/44 (81%), Positives = 40/44 (90%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W
Sbjct: 228 TKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQW 271



 Score = 47.2 bits (107), Expect = 7e-05
 Identities = 20/34 (58%), Positives = 27/34 (79%), Gaps = 2/34 (5%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRK--ISSRFID 768
           +GDRERE GM+ISPMCD+H A++ K  + +R ID
Sbjct: 282 QGDRERERGMEISPMCDKHTASVEKSQVQARGID 315


>AF069491-3|AAC35013.1|  647|Homo sapiens cAMP specific
           phosphodiesterase 4A variant RD1 protein.
          Length = 647

 Score =  156 bits (379), Expect = 7e-38
 Identities = 72/88 (81%), Positives = 82/88 (93%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ D CDIF NL K+QRQ+LRKM
Sbjct: 238 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKM 297

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 298 VIDMVLATDMSKHMTLLADLKTMVETKK 325



 Score =  107 bits (256), Expect = 6e-23
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL   +IP  T + + +TLE+HY  D  +HNSLHAADV QST+VLL T
Sbjct: 153 TCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLAT 212

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AALFAA +HDVD
Sbjct: 213 PALDAVFTDLEILAALFAAAIHDVD 237



 Score = 84.2 bits (199), Expect = 5e-16
 Identities = 45/86 (52%), Positives = 52/86 (60%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV  SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W   +            
Sbjct: 323 TKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRER 382

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
                IS  C       +EKSQVG +
Sbjct: 383 ERGMEISPMC-DKHTASVEKSQVGFI 407



 Score = 68.1 bits (159), Expect = 3e-11
 Identities = 27/39 (69%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 377 QGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 415


>AF069491-2|AAC35015.1|  860|Homo sapiens putative novel cAMP
           specific phosphodiesterase 4A variant protein.
          Length = 860

 Score =  156 bits (379), Expect = 7e-38
 Identities = 72/88 (81%), Positives = 82/88 (93%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ D CDIF NL K+QRQ+LRKM
Sbjct: 451 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKM 510

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 511 VIDMVLATDMSKHMTLLADLKTMVETKK 538



 Score =  107 bits (256), Expect = 6e-23
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL   +IP  T + + +TLE+HY  D  +HNSLHAADV QST+VLL T
Sbjct: 366 TCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLAT 425

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AALFAA +HDVD
Sbjct: 426 PALDAVFTDLEILAALFAAAIHDVD 450



 Score = 84.2 bits (199), Expect = 5e-16
 Identities = 45/86 (52%), Positives = 52/86 (60%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV  SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W   +            
Sbjct: 536 TKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRER 595

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
                IS  C       +EKSQVG +
Sbjct: 596 ERGMEISPMC-DKHTASVEKSQVGFI 620



 Score = 68.1 bits (159), Expect = 3e-11
 Identities = 27/39 (69%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 590 QGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 628


>AF069491-1|AAC35012.1|  886|Homo sapiens cAMP specific
           phosphodiesterase 4A variant pde46 protein.
          Length = 886

 Score =  156 bits (379), Expect = 7e-38
 Identities = 72/88 (81%), Positives = 82/88 (93%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYNDESVLENHHLAV FKLLQ D CDIF NL K+QRQ+LRKM
Sbjct: 477 HPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKM 536

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 537 VIDMVLATDMSKHMTLLADLKTMVETKK 564



 Score =  107 bits (256), Expect = 6e-23
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + Y  F  R+LL   +IP  T + + +TLE+HY  D  +HNSLHAADV QST+VLL T
Sbjct: 392 TCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLAT 451

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL+AVFT LE+ AALFAA +HDVD
Sbjct: 452 PALDAVFTDLEILAALFAAAIHDVD 476



 Score = 84.2 bits (199), Expect = 5e-16
 Identities = 45/86 (52%), Positives = 52/86 (60%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV  SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W   +            
Sbjct: 562 TKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRER 621

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
                IS  C       +EKSQVG +
Sbjct: 622 ERGMEISPMC-DKHTASVEKSQVGFI 646



 Score = 68.1 bits (159), Expect = 3e-11
 Identities = 27/39 (69%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 616 QGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 654


>U50159-1|AAA97892.1|  673|Homo sapiens cAMP-specific
           phoshodiesterase HPDE4D3 variant protein.
          Length = 673

 Score =  152 bits (368), Expect = 2e-36
 Identities = 70/88 (79%), Positives = 81/88 (92%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL KKQRQ+LRKM
Sbjct: 370 HPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKM 429

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VID+VL+TDMSKHM+LLADLKTMVE +K
Sbjct: 430 VIDIVLATDMSKHMNLLADLKTMVETKK 457



 Score =  107 bits (257), Expect = 5e-23
 Identities = 47/85 (55%), Positives = 64/85 (75%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + +T F  R+LL T +IP  T + + +TLE+HY  D  +HN++HAADV QST+VLL+T
Sbjct: 285 TVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST 344

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AA+FA+ +HDVD
Sbjct: 345 PALEAVFTDLEILAAIFASAIHDVD 369



 Score = 84.6 bits (200), Expect = 4e-16
 Identities = 36/44 (81%), Positives = 41/44 (93%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W
Sbjct: 455 TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQW 498



 Score = 70.5 bits (165), Expect = 6e-12
 Identities = 28/39 (71%), Positives = 33/39 (84%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+HNA++ K    FIDYIVHPLW
Sbjct: 509 QGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLW 547


>U50158-1|AAA97891.1|  507|Homo sapiens cAMP-specific
           phosphodiesterase HPDE4D2 variant protein.
          Length = 507

 Score =  152 bits (368), Expect = 2e-36
 Identities = 70/88 (79%), Positives = 81/88 (92%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL KKQRQ+LRKM
Sbjct: 204 HPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKM 263

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VID+VL+TDMSKHM+LLADLKTMVE +K
Sbjct: 264 VIDIVLATDMSKHMNLLADLKTMVETKK 291



 Score =  107 bits (257), Expect = 5e-23
 Identities = 47/85 (55%), Positives = 64/85 (75%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + +T F  R+LL T +IP  T + + +TLE+HY  D  +HN++HAADV QST+VLL+T
Sbjct: 119 TVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST 178

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AA+FA+ +HDVD
Sbjct: 179 PALEAVFTDLEILAAIFASAIHDVD 203



 Score = 84.6 bits (200), Expect = 4e-16
 Identities = 36/44 (81%), Positives = 41/44 (93%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W
Sbjct: 289 TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQW 332



 Score = 70.5 bits (165), Expect = 6e-12
 Identities = 28/39 (71%), Positives = 33/39 (84%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+HNA++ K    FIDYIVHPLW
Sbjct: 343 QGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLW 381


>U50157-1|AAA97890.1|  585|Homo sapiens cAMP-specific
           phosphodiesterase HPDE4D1 variant protein.
          Length = 585

 Score =  152 bits (368), Expect = 2e-36
 Identities = 70/88 (79%), Positives = 81/88 (92%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL KKQRQ+LRKM
Sbjct: 282 HPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKM 341

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VID+VL+TDMSKHM+LLADLKTMVE +K
Sbjct: 342 VIDIVLATDMSKHMNLLADLKTMVETKK 369



 Score =  107 bits (257), Expect = 5e-23
 Identities = 47/85 (55%), Positives = 64/85 (75%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + +T F  R+LL T +IP  T + + +TLE+HY  D  +HN++HAADV QST+VLL+T
Sbjct: 197 TVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST 256

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AA+FA+ +HDVD
Sbjct: 257 PALEAVFTDLEILAAIFASAIHDVD 281



 Score = 84.6 bits (200), Expect = 4e-16
 Identities = 36/44 (81%), Positives = 41/44 (93%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W
Sbjct: 367 TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQW 410



 Score = 70.5 bits (165), Expect = 6e-12
 Identities = 28/39 (71%), Positives = 33/39 (84%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+HNA++ K    FIDYIVHPLW
Sbjct: 421 QGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLW 459


>U02882-1|AAC13745.1|  604|Homo sapiens 3',5'-cyclic AMP
           phosphodiesterase protein.
          Length = 604

 Score =  152 bits (368), Expect = 2e-36
 Identities = 70/88 (79%), Positives = 81/88 (92%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL KKQRQ+LRKM
Sbjct: 301 HPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKM 360

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VID+VL+TDMSKHM+LLADLKTMVE +K
Sbjct: 361 VIDIVLATDMSKHMNLLADLKTMVETKK 388



 Score =  107 bits (257), Expect = 5e-23
 Identities = 47/85 (55%), Positives = 64/85 (75%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + +T F  R+LL T +IP  T + + +TLE+HY  D  +HN++HAADV QST+VLL+T
Sbjct: 216 TVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST 275

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AA+FA+ +HDVD
Sbjct: 276 PALEAVFTDLEILAAIFASAIHDVD 300



 Score = 87.0 bits (206), Expect = 7e-17
 Identities = 46/86 (53%), Positives = 54/86 (62%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV  SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W   +     P      
Sbjct: 386 TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFPQGDRER 445

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
                IS  C       +EKSQVG +
Sbjct: 446 ERGMEISPMC-DKHNASVEKSQVGFI 470



 Score = 70.5 bits (165), Expect = 6e-12
 Identities = 28/39 (71%), Positives = 33/39 (84%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+HNA++ K    FIDYIVHPLW
Sbjct: 440 QGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLW 478


>L20970-1|AAA03592.1|  673|Homo sapiens phosphodiesterase protein.
          Length = 673

 Score =  152 bits (368), Expect = 2e-36
 Identities = 70/88 (79%), Positives = 81/88 (92%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL KKQRQ+LRKM
Sbjct: 370 HPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKM 429

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VID+VL+TDMSKHM+LLADLKTMVE +K
Sbjct: 430 VIDIVLATDMSKHMNLLADLKTMVETKK 457



 Score =  107 bits (257), Expect = 5e-23
 Identities = 47/85 (55%), Positives = 64/85 (75%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + +T F  R+LL T +IP  T + + +TLE+HY  D  +HN++HAADV QST+VLL+T
Sbjct: 285 TVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST 344

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AA+FA+ +HDVD
Sbjct: 345 PALEAVFTDLEILAAIFASAIHDVD 369



 Score = 84.6 bits (200), Expect = 4e-16
 Identities = 36/44 (81%), Positives = 41/44 (93%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W
Sbjct: 455 TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQW 498



 Score = 70.5 bits (165), Expect = 6e-12
 Identities = 28/39 (71%), Positives = 33/39 (84%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+HNA++ K    FIDYIVHPLW
Sbjct: 509 QGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLW 547


>L20969-1|AAC00042.1|  809|Homo sapiens cyclic AMP phosphodiesterase
           protein.
          Length = 809

 Score =  152 bits (368), Expect = 2e-36
 Identities = 70/88 (79%), Positives = 81/88 (92%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL KKQRQ+LRKM
Sbjct: 506 HPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKM 565

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VID+VL+TDMSKHM+LLADLKTMVE +K
Sbjct: 566 VIDIVLATDMSKHMNLLADLKTMVETKK 593



 Score =  107 bits (257), Expect = 5e-23
 Identities = 47/85 (55%), Positives = 64/85 (75%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + +T F  R+LL T +IP  T + + +TLE+HY  D  +HN++HAADV QST+VLL+T
Sbjct: 421 TVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST 480

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AA+FA+ +HDVD
Sbjct: 481 PALEAVFTDLEILAAIFASAIHDVD 505



 Score = 84.6 bits (200), Expect = 4e-16
 Identities = 36/44 (81%), Positives = 41/44 (93%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W
Sbjct: 591 TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQW 634



 Score = 70.5 bits (165), Expect = 6e-12
 Identities = 28/39 (71%), Positives = 33/39 (84%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+HNA++ K    FIDYIVHPLW
Sbjct: 645 QGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLW 683


>AY388960-1|AAQ90404.1|  679|Homo sapiens cAMP-specific
           phosphodiesterase PDE4D9 protein.
          Length = 679

 Score =  152 bits (368), Expect = 2e-36
 Identities = 70/88 (79%), Positives = 81/88 (92%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL KKQRQ+LRKM
Sbjct: 376 HPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKM 435

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VID+VL+TDMSKHM+LLADLKTMVE +K
Sbjct: 436 VIDIVLATDMSKHMNLLADLKTMVETKK 463



 Score =  107 bits (257), Expect = 5e-23
 Identities = 47/85 (55%), Positives = 64/85 (75%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + +T F  R+LL T +IP  T + + +TLE+HY  D  +HN++HAADV QST+VLL+T
Sbjct: 291 TVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST 350

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AA+FA+ +HDVD
Sbjct: 351 PALEAVFTDLEILAAIFASAIHDVD 375



 Score = 84.6 bits (200), Expect = 4e-16
 Identities = 36/44 (81%), Positives = 41/44 (93%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W
Sbjct: 461 TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQW 504



 Score = 70.5 bits (165), Expect = 6e-12
 Identities = 28/39 (71%), Positives = 33/39 (84%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+HNA++ K    FIDYIVHPLW
Sbjct: 515 QGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLW 553


>AY245867-1|AAP75761.1|  679|Homo sapiens cAMP-specific
           phosphodiesterase variant PDE4D9 protein.
          Length = 679

 Score =  152 bits (368), Expect = 2e-36
 Identities = 70/88 (79%), Positives = 81/88 (92%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL KKQRQ+LRKM
Sbjct: 376 HPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKM 435

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VID+VL+TDMSKHM+LLADLKTMVE +K
Sbjct: 436 VIDIVLATDMSKHMNLLADLKTMVETKK 463



 Score =  107 bits (257), Expect = 5e-23
 Identities = 47/85 (55%), Positives = 64/85 (75%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + +T F  R+LL T +IP  T + + +TLE+HY  D  +HN++HAADV QST+VLL+T
Sbjct: 291 TVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST 350

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AA+FA+ +HDVD
Sbjct: 351 PALEAVFTDLEILAAIFASAIHDVD 375



 Score = 84.6 bits (200), Expect = 4e-16
 Identities = 36/44 (81%), Positives = 41/44 (93%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W
Sbjct: 461 TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQW 504



 Score = 70.5 bits (165), Expect = 6e-12
 Identities = 28/39 (71%), Positives = 33/39 (84%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+HNA++ K    FIDYIVHPLW
Sbjct: 515 QGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLW 553


>AY245866-1|AAP75760.1|  748|Homo sapiens cAMP-specific
           phosphodiesterase variant PDE4D7 protein.
          Length = 748

 Score =  152 bits (368), Expect = 2e-36
 Identities = 70/88 (79%), Positives = 81/88 (92%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL KKQRQ+LRKM
Sbjct: 445 HPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKM 504

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VID+VL+TDMSKHM+LLADLKTMVE +K
Sbjct: 505 VIDIVLATDMSKHMNLLADLKTMVETKK 532



 Score =  107 bits (257), Expect = 5e-23
 Identities = 47/85 (55%), Positives = 64/85 (75%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + +T F  R+LL T +IP  T + + +TLE+HY  D  +HN++HAADV QST+VLL+T
Sbjct: 360 TVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST 419

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AA+FA+ +HDVD
Sbjct: 420 PALEAVFTDLEILAAIFASAIHDVD 444



 Score = 84.6 bits (200), Expect = 4e-16
 Identities = 36/44 (81%), Positives = 41/44 (93%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W
Sbjct: 530 TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQW 573



 Score = 70.5 bits (165), Expect = 6e-12
 Identities = 28/39 (71%), Positives = 33/39 (84%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+HNA++ K    FIDYIVHPLW
Sbjct: 584 QGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLW 622


>AF536976-1|AAN10118.1|  748|Homo sapiens cAMP-specific
           phosphodiesterase PDE4D7 protein.
          Length = 748

 Score =  152 bits (368), Expect = 2e-36
 Identities = 70/88 (79%), Positives = 81/88 (92%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL KKQRQ+LRKM
Sbjct: 445 HPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKM 504

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VID+VL+TDMSKHM+LLADLKTMVE +K
Sbjct: 505 VIDIVLATDMSKHMNLLADLKTMVETKK 532



 Score =  107 bits (257), Expect = 5e-23
 Identities = 47/85 (55%), Positives = 64/85 (75%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + +T F  R+LL T +IP  T + + +TLE+HY  D  +HN++HAADV QST+VLL+T
Sbjct: 360 TVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST 419

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AA+FA+ +HDVD
Sbjct: 420 PALEAVFTDLEILAAIFASAIHDVD 444



 Score = 84.6 bits (200), Expect = 4e-16
 Identities = 36/44 (81%), Positives = 41/44 (93%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W
Sbjct: 530 TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQW 573



 Score = 70.5 bits (165), Expect = 6e-12
 Identities = 28/39 (71%), Positives = 33/39 (84%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+HNA++ K    FIDYIVHPLW
Sbjct: 584 QGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLW 622


>AF536975-1|AAN10117.1|  518|Homo sapiens cAMP-specific
           phosphodiesterase PDE4D6 protein.
          Length = 518

 Score =  152 bits (368), Expect = 2e-36
 Identities = 70/88 (79%), Positives = 81/88 (92%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL KKQRQ+LRKM
Sbjct: 215 HPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKM 274

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VID+VL+TDMSKHM+LLADLKTMVE +K
Sbjct: 275 VIDIVLATDMSKHMNLLADLKTMVETKK 302



 Score =  107 bits (257), Expect = 5e-23
 Identities = 47/85 (55%), Positives = 64/85 (75%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + +T F  R+LL T +IP  T + + +TLE+HY  D  +HN++HAADV QST+VLL+T
Sbjct: 130 TVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST 189

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AA+FA+ +HDVD
Sbjct: 190 PALEAVFTDLEILAAIFASAIHDVD 214



 Score = 84.6 bits (200), Expect = 4e-16
 Identities = 36/44 (81%), Positives = 41/44 (93%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W
Sbjct: 300 TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQW 343



 Score = 70.5 bits (165), Expect = 6e-12
 Identities = 28/39 (71%), Positives = 33/39 (84%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+HNA++ K    FIDYIVHPLW
Sbjct: 354 QGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLW 392


>AF012074-1|AAC00070.1|  507|Homo sapiens cAMP-specific
           phosphodiesterase PDE4D2 protein.
          Length = 507

 Score =  152 bits (368), Expect = 2e-36
 Identities = 70/88 (79%), Positives = 81/88 (92%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL KKQRQ+LRKM
Sbjct: 204 HPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKM 263

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VID+VL+TDMSKHM+LLADLKTMVE +K
Sbjct: 264 VIDIVLATDMSKHMNLLADLKTMVETKK 291



 Score =  107 bits (257), Expect = 5e-23
 Identities = 47/85 (55%), Positives = 64/85 (75%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + +T F  R+LL T +IP  T + + +TLE+HY  D  +HN++HAADV QST+VLL+T
Sbjct: 119 TVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST 178

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AA+FA+ +HDVD
Sbjct: 179 PALEAVFTDLEILAAIFASAIHDVD 203



 Score = 84.6 bits (200), Expect = 4e-16
 Identities = 36/44 (81%), Positives = 41/44 (93%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W
Sbjct: 289 TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQW 332



 Score = 70.5 bits (165), Expect = 6e-12
 Identities = 28/39 (71%), Positives = 33/39 (84%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+HNA++ K    FIDYIVHPLW
Sbjct: 343 QGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLW 381


>AF012073-1|AAC00069.1|  745|Homo sapiens cAMP-specific
           phosphodiesterase PDE4D5 protein.
          Length = 745

 Score =  152 bits (368), Expect = 2e-36
 Identities = 70/88 (79%), Positives = 81/88 (92%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL KKQRQ+LRKM
Sbjct: 442 HPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKM 501

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VID+VL+TDMSKHM+LLADLKTMVE +K
Sbjct: 502 VIDIVLATDMSKHMNLLADLKTMVETKK 529



 Score =  107 bits (257), Expect = 5e-23
 Identities = 47/85 (55%), Positives = 64/85 (75%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + +T F  R+LL T +IP  T + + +TLE+HY  D  +HN++HAADV QST+VLL+T
Sbjct: 357 TVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST 416

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AA+FA+ +HDVD
Sbjct: 417 PALEAVFTDLEILAAIFASAIHDVD 441



 Score = 84.6 bits (200), Expect = 4e-16
 Identities = 36/44 (81%), Positives = 41/44 (93%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W
Sbjct: 527 TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQW 570



 Score = 70.5 bits (165), Expect = 6e-12
 Identities = 28/39 (71%), Positives = 33/39 (84%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+HNA++ K    FIDYIVHPLW
Sbjct: 581 QGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLW 619


>BC036319-1|AAH36319.1|  518|Homo sapiens PDE4D protein protein.
          Length = 518

 Score =  151 bits (365), Expect = 4e-36
 Identities = 70/88 (79%), Positives = 80/88 (90%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG+ NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL KKQRQ+LRKM
Sbjct: 215 HPGVFNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKM 274

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VID+VL+TDMSKHM+LLADLKTMVE +K
Sbjct: 275 VIDIVLATDMSKHMNLLADLKTMVETKK 302



 Score =  107 bits (257), Expect = 5e-23
 Identities = 47/85 (55%), Positives = 64/85 (75%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + +T F  R+LL T +IP  T + + +TLE+HY  D  +HN++HAADV QST+VLL+T
Sbjct: 130 TVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST 189

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AA+FA+ +HDVD
Sbjct: 190 PALEAVFTDLEILAAIFASAIHDVD 214



 Score = 84.6 bits (200), Expect = 4e-16
 Identities = 36/44 (81%), Positives = 41/44 (93%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W
Sbjct: 300 TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQW 343



 Score = 70.5 bits (165), Expect = 6e-12
 Identities = 28/39 (71%), Positives = 33/39 (84%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+HNA++ K    FIDYIVHPLW
Sbjct: 354 QGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLW 392


>AF536977-1|AAN10119.1|  687|Homo sapiens cAMP-specific
           phosphodiesterase PDE4D8 protein.
          Length = 687

 Score =  149 bits (361), Expect = 1e-35
 Identities = 69/88 (78%), Positives = 80/88 (90%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + C IF NL KKQRQ+LRKM
Sbjct: 384 HPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCGIFQNLTKKQRQSLRKM 443

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VID+VL+TDMSKHM+LLADLKTMVE +K
Sbjct: 444 VIDIVLATDMSKHMNLLADLKTMVETKK 471



 Score =  107 bits (257), Expect = 5e-23
 Identities = 47/85 (55%), Positives = 64/85 (75%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           T + +T F  R+LL T +IP  T + + +TLE+HY  D  +HN++HAADV QST+VLL+T
Sbjct: 299 TVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST 358

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AA+FA+ +HDVD
Sbjct: 359 PALEAVFTDLEILAAIFASAIHDVD 383



 Score = 84.6 bits (200), Expect = 4e-16
 Identities = 36/44 (81%), Positives = 41/44 (93%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           TKKV  SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W
Sbjct: 469 TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQW 512



 Score = 70.5 bits (165), Expect = 6e-12
 Identities = 28/39 (71%), Positives = 33/39 (84%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+HNA++ K    FIDYIVHPLW
Sbjct: 523 QGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLW 561


>U88713-1|AAC51916.1|  700|Homo sapiens phosphodiesterase 4C
           protein.
          Length = 700

 Score =  146 bits (354), Expect = 8e-35
 Identities = 68/88 (77%), Positives = 79/88 (89%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL  KQR +LR+M
Sbjct: 420 HPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRM 479

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 480 VIDMVLATDMSKHMNLLADLKTMVETKK 507



 Score =  105 bits (252), Expect = 2e-22
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           TA+ ++ F  R+LL T QIPA T   + + LE HY  +  +HNSLHAADV QST+VLL T
Sbjct: 335 TAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLAT 394

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AALFA+ +HDVD
Sbjct: 395 PALEAVFTDLEILAALFASAIHDVD 419



 Score = 86.6 bits (205), Expect = 9e-17
 Identities = 46/86 (53%), Positives = 54/86 (62%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV   GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W   +            
Sbjct: 505 TKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRER 564

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
            +   IS  C       +EKSQVG +
Sbjct: 565 ESGLDISPMC-DKHTASVEKSQVGFI 589



 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 26/39 (66%), Positives = 31/39 (79%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE G+DISPMCD+H A++ K    FIDYI HPLW
Sbjct: 559 QGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLW 597


>U88712-1|AAC51915.1|  606|Homo sapiens phosphodiesterase 4C
           protein.
          Length = 606

 Score =  146 bits (354), Expect = 8e-35
 Identities = 68/88 (77%), Positives = 79/88 (89%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL  KQR +LR+M
Sbjct: 326 HPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRM 385

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 386 VIDMVLATDMSKHMNLLADLKTMVETKK 413



 Score =  105 bits (252), Expect = 2e-22
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           TA+ ++ F  R+LL T QIPA T   + + LE HY  +  +HNSLHAADV QST+VLL T
Sbjct: 241 TAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLAT 300

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AALFA+ +HDVD
Sbjct: 301 PALEAVFTDLEILAALFASAIHDVD 325



 Score = 86.6 bits (205), Expect = 9e-17
 Identities = 46/86 (53%), Positives = 54/86 (62%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV   GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W   +            
Sbjct: 411 TKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRER 470

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
            +   IS  C       +EKSQVG +
Sbjct: 471 ESGLDISPMC-DKHTASVEKSQVGFI 495



 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 26/39 (66%), Positives = 31/39 (79%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE G+DISPMCD+H A++ K    FIDYI HPLW
Sbjct: 465 QGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLW 503


>U66349-1|AAB96878.1|  427|Homo sapiens PDE4C-delta109 protein.
          Length = 427

 Score =  146 bits (354), Expect = 8e-35
 Identities = 68/88 (77%), Positives = 79/88 (89%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL  KQR +LR+M
Sbjct: 147 HPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRM 206

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 207 VIDMVLATDMSKHMNLLADLKTMVETKK 234



 Score = 86.6 bits (205), Expect = 9e-17
 Identities = 46/86 (53%), Positives = 54/86 (62%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV   GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W   +            
Sbjct: 232 TKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRER 291

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
            +   IS  C       +EKSQVG +
Sbjct: 292 ESGLDISPMC-DKHTASVEKSQVGFI 316



 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 26/39 (66%), Positives = 31/39 (79%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE G+DISPMCD+H A++ K    FIDYI HPLW
Sbjct: 286 QGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLW 324



 Score = 35.9 bits (79), Expect = 0.17
 Identities = 15/21 (71%), Positives = 18/21 (85%)
 Frame = +1

Query: 193 AVFTPLEVCAALFAACVHDVD 255
           AVFT LE+ AALFA+ +HDVD
Sbjct: 126 AVFTDLEILAALFASAIHDVD 146


>U66348-1|AAB96877.1|  518|Homo sapiens PDE4C-delta54 protein.
          Length = 518

 Score =  146 bits (354), Expect = 8e-35
 Identities = 68/88 (77%), Positives = 79/88 (89%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL  KQR +LR+M
Sbjct: 238 HPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRM 297

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 298 VIDMVLATDMSKHMNLLADLKTMVETKK 325



 Score =  105 bits (252), Expect = 2e-22
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           TA+ ++ F  R+LL T QIPA T   + + LE HY  +  +HNSLHAADV QST+VLL T
Sbjct: 153 TAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLAT 212

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AALFA+ +HDVD
Sbjct: 213 PALEAVFTDLEILAALFASAIHDVD 237



 Score = 86.6 bits (205), Expect = 9e-17
 Identities = 46/86 (53%), Positives = 54/86 (62%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV   GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W   +            
Sbjct: 323 TKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRER 382

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
            +   IS  C       +EKSQVG +
Sbjct: 383 ESGLDISPMC-DKHTASVEKSQVGFI 407



 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 26/39 (66%), Positives = 31/39 (79%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE G+DISPMCD+H A++ K    FIDYI HPLW
Sbjct: 377 QGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLW 415


>U66347-1|AAB96876.1|  426|Homo sapiens PDE4C-426 protein.
          Length = 426

 Score =  146 bits (354), Expect = 8e-35
 Identities = 68/88 (77%), Positives = 79/88 (89%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL  KQR +LR+M
Sbjct: 146 HPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRM 205

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 206 VIDMVLATDMSKHMNLLADLKTMVETKK 233



 Score =  105 bits (252), Expect = 2e-22
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           TA+ ++ F  R+LL T QIPA T   + + LE HY  +  +HNSLHAADV QST+VLL T
Sbjct: 61  TAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLAT 120

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AALFA+ +HDVD
Sbjct: 121 PALEAVFTDLEILAALFASAIHDVD 145



 Score = 86.6 bits (205), Expect = 9e-17
 Identities = 46/86 (53%), Positives = 54/86 (62%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV   GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W   +            
Sbjct: 231 TKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRER 290

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
            +   IS  C       +EKSQVG +
Sbjct: 291 ESGLDISPMC-DKHTASVEKSQVGFI 315



 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 26/39 (66%), Positives = 31/39 (79%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE G+DISPMCD+H A++ K    FIDYI HPLW
Sbjct: 285 QGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLW 323


>U66346-1|AAB96875.1|  791|Homo sapiens PDE4C-791 protein.
          Length = 791

 Score =  146 bits (354), Expect = 8e-35
 Identities = 68/88 (77%), Positives = 79/88 (89%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL  KQR +LR+M
Sbjct: 511 HPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRM 570

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 571 VIDMVLATDMSKHMNLLADLKTMVETKK 598



 Score =  105 bits (252), Expect = 2e-22
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           TA+ ++ F  R+LL T QIPA T   + + LE HY  +  +HNSLHAADV QST+VLL T
Sbjct: 426 TAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLAT 485

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AALFA+ +HDVD
Sbjct: 486 PALEAVFTDLEILAALFASAIHDVD 510



 Score = 86.6 bits (205), Expect = 9e-17
 Identities = 46/86 (53%), Positives = 54/86 (62%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV   GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W   +            
Sbjct: 596 TKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRER 655

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
            +   IS  C       +EKSQVG +
Sbjct: 656 ESGLDISPMC-DKHTASVEKSQVGFI 680



 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 26/39 (66%), Positives = 31/39 (79%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE G+DISPMCD+H A++ K    FIDYI HPLW
Sbjct: 650 QGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLW 688


>BC109068-1|AAI09069.1|  549|Homo sapiens PDE4C protein protein.
          Length = 549

 Score =  146 bits (354), Expect = 8e-35
 Identities = 68/88 (77%), Positives = 79/88 (89%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL  KQR +LR+M
Sbjct: 269 HPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRM 328

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 329 VIDMVLATDMSKHMNLLADLKTMVETKK 356



 Score =  105 bits (252), Expect = 2e-22
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           TA+ ++ F  R+LL T QIPA T   + + LE HY  +  +HNSLHAADV QST+VLL T
Sbjct: 184 TAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLAT 243

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AALFA+ +HDVD
Sbjct: 244 PALEAVFTDLEILAALFASAIHDVD 268



 Score = 86.6 bits (205), Expect = 9e-17
 Identities = 46/86 (53%), Positives = 54/86 (62%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV   GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W   +            
Sbjct: 354 TKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRER 413

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
            +   IS  C       +EKSQVG +
Sbjct: 414 ESGLDISPMC-DKHTASVEKSQVGFI 438



 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 26/39 (66%), Positives = 31/39 (79%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE G+DISPMCD+H A++ K    FIDYI HPLW
Sbjct: 408 QGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLW 446


>BC109067-1|AAI09068.1|  481|Homo sapiens PDE4C protein protein.
          Length = 481

 Score =  146 bits (354), Expect = 8e-35
 Identities = 68/88 (77%), Positives = 79/88 (89%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL  KQR +LR+M
Sbjct: 201 HPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRM 260

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 261 VIDMVLATDMSKHMNLLADLKTMVETKK 288



 Score =  105 bits (252), Expect = 2e-22
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           TA+ ++ F  R+LL T QIPA T   + + LE HY  +  +HNSLHAADV QST+VLL T
Sbjct: 116 TAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLAT 175

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AALFA+ +HDVD
Sbjct: 176 PALEAVFTDLEILAALFASAIHDVD 200



 Score = 86.6 bits (205), Expect = 9e-17
 Identities = 46/86 (53%), Positives = 54/86 (62%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV   GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W   +            
Sbjct: 286 TKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRER 345

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
            +   IS  C       +EKSQVG +
Sbjct: 346 ESGLDISPMC-DKHTASVEKSQVGFI 370



 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 26/39 (66%), Positives = 31/39 (79%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE G+DISPMCD+H A++ K    FIDYI HPLW
Sbjct: 340 QGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLW 378


>AF157816-3|AAD47055.1|  606|Homo sapiens cAMP specific
           phosphodiesterase PDE4C2 variant protein.
          Length = 606

 Score =  146 bits (354), Expect = 8e-35
 Identities = 68/88 (77%), Positives = 79/88 (89%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL  KQR +LR+M
Sbjct: 326 HPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRM 385

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 386 VIDMVLATDMSKHMNLLADLKTMVETKK 413



 Score =  105 bits (252), Expect = 2e-22
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           TA+ ++ F  R+LL T QIPA T   + + LE HY  +  +HNSLHAADV QST+VLL T
Sbjct: 241 TAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLAT 300

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AALFA+ +HDVD
Sbjct: 301 PALEAVFTDLEILAALFASAIHDVD 325



 Score = 86.6 bits (205), Expect = 9e-17
 Identities = 46/86 (53%), Positives = 54/86 (62%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV   GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W   +            
Sbjct: 411 TKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRER 470

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
            +   IS  C       +EKSQVG +
Sbjct: 471 ESGLDISPMC-DKHTASVEKSQVGFI 495



 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 26/39 (66%), Positives = 31/39 (79%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE G+DISPMCD+H A++ K    FIDYI HPLW
Sbjct: 465 QGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLW 503


>AF157816-2|AAD47054.1|  680|Homo sapiens cAMP specific
           phosphodiesterase PDE4C3 variant protein.
          Length = 680

 Score =  146 bits (354), Expect = 8e-35
 Identities = 68/88 (77%), Positives = 79/88 (89%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL  KQR +LR+M
Sbjct: 400 HPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRM 459

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 460 VIDMVLATDMSKHMNLLADLKTMVETKK 487



 Score =  105 bits (252), Expect = 2e-22
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           TA+ ++ F  R+LL T QIPA T   + + LE HY  +  +HNSLHAADV QST+VLL T
Sbjct: 315 TAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLAT 374

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AALFA+ +HDVD
Sbjct: 375 PALEAVFTDLEILAALFASAIHDVD 399



 Score = 86.6 bits (205), Expect = 9e-17
 Identities = 46/86 (53%), Positives = 54/86 (62%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV   GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W   +            
Sbjct: 485 TKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRER 544

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
            +   IS  C       +EKSQVG +
Sbjct: 545 ESGLDISPMC-DKHTASVEKSQVGFI 569



 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 26/39 (66%), Positives = 31/39 (79%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE G+DISPMCD+H A++ K    FIDYI HPLW
Sbjct: 539 QGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLW 577


>AF157816-1|AAD47053.1|  712|Homo sapiens cAMP specific
           phosphodiesterase PDE4C1 variant protein.
          Length = 712

 Score =  146 bits (354), Expect = 8e-35
 Identities = 68/88 (77%), Positives = 79/88 (89%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL  KQR +LR+M
Sbjct: 432 HPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRM 491

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 492 VIDMVLATDMSKHMNLLADLKTMVETKK 519



 Score =  105 bits (252), Expect = 2e-22
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           TA+ ++ F  R+LL T QIPA T   + + LE HY  +  +HNSLHAADV QST+VLL T
Sbjct: 347 TAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLAT 406

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AALFA+ +HDVD
Sbjct: 407 PALEAVFTDLEILAALFASAIHDVD 431



 Score = 86.6 bits (205), Expect = 9e-17
 Identities = 46/86 (53%), Positives = 54/86 (62%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV   GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W   +            
Sbjct: 517 TKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRER 576

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
            +   IS  C       +EKSQVG +
Sbjct: 577 ESGLDISPMC-DKHTASVEKSQVGFI 601



 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 26/39 (66%), Positives = 31/39 (79%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE G+DISPMCD+H A++ K    FIDYI HPLW
Sbjct: 571 QGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLW 609


>AC005759-5|AAC83049.1|  426|Homo sapiens PDE4C-426 protein.
          Length = 426

 Score =  146 bits (354), Expect = 8e-35
 Identities = 68/88 (77%), Positives = 79/88 (89%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL  KQR +LR+M
Sbjct: 146 HPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRM 205

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 206 VIDMVLATDMSKHMNLLADLKTMVETKK 233



 Score =  105 bits (252), Expect = 2e-22
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           TA+ ++ F  R+LL T QIPA T   + + LE HY  +  +HNSLHAADV QST+VLL T
Sbjct: 61  TAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLAT 120

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AALFA+ +HDVD
Sbjct: 121 PALEAVFTDLEILAALFASAIHDVD 145



 Score = 86.6 bits (205), Expect = 9e-17
 Identities = 46/86 (53%), Positives = 54/86 (62%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV   GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W   +            
Sbjct: 231 TKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRER 290

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
            +   IS  C       +EKSQVG +
Sbjct: 291 ESGLDISPMC-DKHTASVEKSQVGFI 315



 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 26/39 (66%), Positives = 31/39 (79%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE G+DISPMCD+H A++ K    FIDYI HPLW
Sbjct: 285 QGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLW 323


>AC005759-4|AAC83048.1|  427|Homo sapiens PDE4C-delta109 protein.
          Length = 427

 Score =  146 bits (354), Expect = 8e-35
 Identities = 68/88 (77%), Positives = 79/88 (89%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL  KQR +LR+M
Sbjct: 147 HPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRM 206

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 207 VIDMVLATDMSKHMNLLADLKTMVETKK 234



 Score = 86.6 bits (205), Expect = 9e-17
 Identities = 46/86 (53%), Positives = 54/86 (62%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV   GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W   +            
Sbjct: 232 TKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRER 291

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
            +   IS  C       +EKSQVG +
Sbjct: 292 ESGLDISPMC-DKHTASVEKSQVGFI 316



 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 26/39 (66%), Positives = 31/39 (79%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE G+DISPMCD+H A++ K    FIDYI HPLW
Sbjct: 286 QGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLW 324



 Score = 35.9 bits (79), Expect = 0.17
 Identities = 15/21 (71%), Positives = 18/21 (85%)
 Frame = +1

Query: 193 AVFTPLEVCAALFAACVHDVD 255
           AVFT LE+ AALFA+ +HDVD
Sbjct: 126 AVFTDLEILAALFASAIHDVD 146


>AC005759-3|AAC83051.1|  518|Homo sapiens PDE4C-delta54 protein.
          Length = 518

 Score =  146 bits (354), Expect = 8e-35
 Identities = 68/88 (77%), Positives = 79/88 (89%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL  KQR +LR+M
Sbjct: 238 HPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRM 297

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 298 VIDMVLATDMSKHMNLLADLKTMVETKK 325



 Score =  105 bits (252), Expect = 2e-22
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           TA+ ++ F  R+LL T QIPA T   + + LE HY  +  +HNSLHAADV QST+VLL T
Sbjct: 153 TAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLAT 212

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AALFA+ +HDVD
Sbjct: 213 PALEAVFTDLEILAALFASAIHDVD 237



 Score = 86.6 bits (205), Expect = 9e-17
 Identities = 46/86 (53%), Positives = 54/86 (62%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV   GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W   +            
Sbjct: 323 TKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRER 382

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
            +   IS  C       +EKSQVG +
Sbjct: 383 ESGLDISPMC-DKHTASVEKSQVGFI 407



 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 26/39 (66%), Positives = 31/39 (79%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE G+DISPMCD+H A++ K    FIDYI HPLW
Sbjct: 377 QGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLW 415


>AC005759-1|AAC83050.1|  782|Homo sapiens PDE4C-791 protein.
          Length = 782

 Score =  146 bits (354), Expect = 8e-35
 Identities = 68/88 (77%), Positives = 79/88 (89%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++SELALMYND SVLENHHLAV FKLLQ + CDIF NL  KQR +LR+M
Sbjct: 502 HPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRM 561

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 562 VIDMVLATDMSKHMNLLADLKTMVETKK 589



 Score =  105 bits (252), Expect = 2e-22
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           TA+ ++ F  R+LL T QIPA T   + + LE HY  +  +HNSLHAADV QST+VLL T
Sbjct: 417 TAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLAT 476

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AALFA+ +HDVD
Sbjct: 477 PALEAVFTDLEILAALFASAIHDVD 501



 Score = 86.6 bits (205), Expect = 9e-17
 Identities = 46/86 (53%), Positives = 54/86 (62%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV   GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W   +            
Sbjct: 587 TKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRER 646

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
            +   IS  C       +EKSQVG +
Sbjct: 647 ESGLDISPMC-DKHTASVEKSQVGFI 671



 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 26/39 (66%), Positives = 31/39 (79%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE G+DISPMCD+H A++ K    FIDYI HPLW
Sbjct: 641 QGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLW 679


>Z46632-1|CAA86601.1|  712|Homo sapiens 3',5'-cyclic AMP
           phosphodiesterase protein.
          Length = 712

 Score =  144 bits (348), Expect = 4e-34
 Identities = 66/88 (75%), Positives = 79/88 (89%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N++S++ALMYND SVLENHHLAV FKLLQ + CDIF NL  KQR +LR+M
Sbjct: 432 HPGVSNQFLINTNSDVALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRM 491

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 492 VIDMVLATDMSKHMNLLADLKTMVETKK 519



 Score =  105 bits (252), Expect = 2e-22
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           TA+ ++ F  R+LL T QIPA T   + + LE HY  +  +HNSLHAADV QST+VLL T
Sbjct: 347 TAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLAT 406

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AALFA+ +HDVD
Sbjct: 407 PALEAVFTDLEILAALFASAIHDVD 431



 Score = 86.6 bits (205), Expect = 9e-17
 Identities = 46/86 (53%), Positives = 54/86 (62%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV   GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W   +            
Sbjct: 517 TKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRER 576

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
            +   IS  C       +EKSQVG +
Sbjct: 577 ESGLDISPMC-DKHTASVEKSQVGFI 601



 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 26/39 (66%), Positives = 31/39 (79%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE G+DISPMCD+H A++ K    FIDYI HPLW
Sbjct: 571 QGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLW 609


>AC005759-2|AAC83047.1|  710|Homo sapiens CN4C_HUMAN protein.
          Length = 710

 Score =  137 bits (332), Expect = 4e-32
 Identities = 66/88 (75%), Positives = 77/88 (87%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG++NQFL+N+  +LALMYND SVLENHHLAV FKLLQ + CDIF NL  KQR +LR+M
Sbjct: 432 HPGVSNQFLINT--KLALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRM 489

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRK 518
           VIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 490 VIDMVLATDMSKHMNLLADLKTMVETKK 517



 Score =  105 bits (252), Expect = 2e-22
 Identities = 50/85 (58%), Positives = 62/85 (72%)
 Frame = +1

Query: 1   TAVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNT 180
           TA+ ++ F  R+LL T QIPA T   + + LE HY  +  +HNSLHAADV QST+VLL T
Sbjct: 347 TAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLAT 406

Query: 181 PALNAVFTPLEVCAALFAACVHDVD 255
           PAL AVFT LE+ AALFA+ +HDVD
Sbjct: 407 PALEAVFTDLEILAALFASAIHDVD 431



 Score = 86.6 bits (205), Expect = 9e-17
 Identities = 46/86 (53%), Positives = 54/86 (62%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV   GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W   +            
Sbjct: 515 TKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRER 574

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
            +   IS  C       +EKSQVG +
Sbjct: 575 ESGLDISPMC-DKHTASVEKSQVGFI 599



 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 26/39 (66%), Positives = 31/39 (79%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE G+DISPMCD+H A++ K    FIDYI HPLW
Sbjct: 569 QGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLW 607


>U86078-1|AAC51872.1|  536|Homo sapiens calmodulin-stimulated
           phosphodiesterase PDE1B1 protein.
          Length = 536

 Score = 92.7 bits (220), Expect = 1e-18
 Identities = 41/86 (47%), Positives = 61/86 (70%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G TN F + + SE A++YND SVLENHH++  F+L+Q+D  +IF+NL K +   LR +
Sbjct: 267 HTGTTNSFHIQTKSECAIVYNDRSVLENHHISSVFRLMQDDEMNIFINLTKDEFVELRAL 326

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           VI+MVL+TDMS H   +  +KT +++
Sbjct: 327 VIEMVLATDMSCHFQQVKTMKTALQQ 352



 Score = 57.6 bits (133), Expect = 5e-08
 Identities = 27/84 (32%), Positives = 46/84 (54%), Gaps = 1/84 (1%)
 Frame = +1

Query: 7   VAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIR-DNPFHNSLHAADVTQSTNVLLNTP 183
           + +   T   L++  +IP    ++F   LE  Y +  NP+HN +HAADVTQ+ +  L   
Sbjct: 183 IVFELLTRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRT 242

Query: 184 ALNAVFTPLEVCAALFAACVHDVD 255
            +    + +E+ A +FAA +HD +
Sbjct: 243 GMVHCLSEIELLAIIFAAAIHDYE 266



 Score = 40.3 bits (90), Expect = 0.008
 Identities = 16/37 (43%), Positives = 24/37 (64%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHP 783
           +GD+E E G+  SP+CDR +  + +    FID+IV P
Sbjct: 395 QGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFIVEP 431



 Score = 31.9 bits (69), Expect = 2.7
 Identities = 13/32 (40%), Positives = 20/32 (62%)
 Frame = +2

Query: 557 DRIQVLENLVHCADLSNPTKPLPLYKRWVALL 652
           D+ + L  L+H AD+S+PTK   ++ RW   L
Sbjct: 357 DKPKALSLLLHAADISHPTKQWLVHSRWTKAL 388


>U56976-1|AAC50769.1|  536|Homo sapiens calmodulin dependent
           phosphodiesterase PDE1B1 protein.
          Length = 536

 Score = 92.7 bits (220), Expect = 1e-18
 Identities = 41/86 (47%), Positives = 61/86 (70%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G TN F + + SE A++YND SVLENHH++  F+L+Q+D  +IF+NL K +   LR +
Sbjct: 267 HTGTTNSFHIQTKSECAIVYNDRSVLENHHISSVFRLMQDDEMNIFINLTKDEFVELRAL 326

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           VI+MVL+TDMS H   +  +KT +++
Sbjct: 327 VIEMVLATDMSCHFQQVKTMKTALQQ 352



 Score = 57.6 bits (133), Expect = 5e-08
 Identities = 27/84 (32%), Positives = 46/84 (54%), Gaps = 1/84 (1%)
 Frame = +1

Query: 7   VAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIR-DNPFHNSLHAADVTQSTNVLLNTP 183
           + +   T   L++  +IP    ++F   LE  Y +  NP+HN +HAADVTQ+ +  L   
Sbjct: 183 IVFELLTRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRT 242

Query: 184 ALNAVFTPLEVCAALFAACVHDVD 255
            +    + +E+ A +FAA +HD +
Sbjct: 243 GMVHCLSEIELLAIIFAAAIHDYE 266



 Score = 40.3 bits (90), Expect = 0.008
 Identities = 16/37 (43%), Positives = 24/37 (64%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHP 783
           +GD+E E G+  SP+CDR +  + +    FID+IV P
Sbjct: 395 QGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFIVEP 431



 Score = 31.9 bits (69), Expect = 2.7
 Identities = 13/32 (40%), Positives = 20/32 (62%)
 Frame = +2

Query: 557 DRIQVLENLVHCADLSNPTKPLPLYKRWVALL 652
           D+ + L  L+H AD+S+PTK   ++ RW   L
Sbjct: 357 DKPKALSLLLHAADISHPTKQWLVHSRWTKAL 388


>U40584-1|AAB50018.1|  184|Homo sapiens
           calcium/calmodulin-stimulated cyclic nucleotide
           phosphodiesterase protein.
          Length = 184

 Score = 92.7 bits (220), Expect = 1e-18
 Identities = 41/86 (47%), Positives = 61/86 (70%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G TN F + + SE A++YND SVLENHH++  F+L+Q+D  +IF+NL K +   LR +
Sbjct: 67  HTGTTNSFHIQTKSECAIVYNDRSVLENHHISSVFRLMQDDEMNIFINLTKDEFVELRAL 126

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           VI+MVL+TDMS H   +  +KT +++
Sbjct: 127 VIEMVLATDMSCHFQQVKTMKTALQQ 152



 Score = 49.6 bits (113), Expect = 1e-05
 Identities = 23/63 (36%), Positives = 38/63 (60%), Gaps = 1/63 (1%)
 Frame = +1

Query: 70  FLAFAVTLEEHYIR-DNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVH 246
           +++F   LE  Y +  NP+HN +HAADVTQ+ +  L    +    + +E+ A +FAA +H
Sbjct: 4   WMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEIELLAIIFAAAIH 63

Query: 247 DVD 255
           D +
Sbjct: 64  DYE 66



 Score = 31.5 bits (68), Expect = 3.6
 Identities = 12/28 (42%), Positives = 19/28 (67%)
 Frame = +2

Query: 557 DRIQVLENLVHCADLSNPTKPLPLYKRW 640
           D+ + L  L+H AD+S+PTK   ++ RW
Sbjct: 157 DKSKALSLLLHAADISHPTKQWLVHSRW 184


>BX538092-1|CAD98011.1|  399|Homo sapiens hypothetical protein
           protein.
          Length = 399

 Score = 92.7 bits (220), Expect = 1e-18
 Identities = 41/86 (47%), Positives = 61/86 (70%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G TN F + + SE A++YND SVLENHH++  F+L+Q+D  +IF+NL K +   LR +
Sbjct: 130 HTGTTNSFHIQTKSECAIVYNDRSVLENHHISSVFRLMQDDEMNIFINLTKDEFVELRAL 189

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           VI+MVL+TDMS H   +  +KT +++
Sbjct: 190 VIEMVLATDMSCHFQQVKTMKTALQQ 215



 Score = 57.6 bits (133), Expect = 5e-08
 Identities = 27/84 (32%), Positives = 46/84 (54%), Gaps = 1/84 (1%)
 Frame = +1

Query: 7   VAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIR-DNPFHNSLHAADVTQSTNVLLNTP 183
           + +   T   L++  +IP    ++F   LE  Y +  NP+HN +HAADVTQ+ +  L   
Sbjct: 46  IVFELLTRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRT 105

Query: 184 ALNAVFTPLEVCAALFAACVHDVD 255
            +    + +E+ A +FAA +HD +
Sbjct: 106 GMVHCLSEIELLAIIFAAAIHDYE 129



 Score = 40.3 bits (90), Expect = 0.008
 Identities = 16/37 (43%), Positives = 24/37 (64%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHP 783
           +GD+E E G+  SP+CDR +  + +    FID+IV P
Sbjct: 258 QGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFIVEP 294



 Score = 31.9 bits (69), Expect = 2.7
 Identities = 13/32 (40%), Positives = 20/32 (62%)
 Frame = +2

Query: 557 DRIQVLENLVHCADLSNPTKPLPLYKRWVALL 652
           D+ + L  L+H AD+S+PTK   ++ RW   L
Sbjct: 220 DKPKALSLLLHAADISHPTKQWLVHSRWTKAL 251


>BC032226-1|AAH32226.1|  536|Homo sapiens phosphodiesterase 1B,
           calmodulin-dependent protein.
          Length = 536

 Score = 92.7 bits (220), Expect = 1e-18
 Identities = 41/86 (47%), Positives = 61/86 (70%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G TN F + + SE A++YND SVLENHH++  F+L+Q+D  +IF+NL K +   LR +
Sbjct: 267 HTGTTNSFHIQTKSECAIVYNDRSVLENHHISSVFRLMQDDEMNIFINLTKDEFVELRAL 326

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           VI+MVL+TDMS H   +  +KT +++
Sbjct: 327 VIEMVLATDMSCHFQQVKTMKTALQQ 352



 Score = 57.6 bits (133), Expect = 5e-08
 Identities = 27/84 (32%), Positives = 46/84 (54%), Gaps = 1/84 (1%)
 Frame = +1

Query: 7   VAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIR-DNPFHNSLHAADVTQSTNVLLNTP 183
           + +   T   L++  +IP    ++F   LE  Y +  NP+HN +HAADVTQ+ +  L   
Sbjct: 183 IVFELLTRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRT 242

Query: 184 ALNAVFTPLEVCAALFAACVHDVD 255
            +    + +E+ A +FAA +HD +
Sbjct: 243 GMVHCLSEIELLAIIFAAAIHDYE 266



 Score = 40.3 bits (90), Expect = 0.008
 Identities = 16/37 (43%), Positives = 24/37 (64%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHP 783
           +GD+E E G+  SP+CDR +  + +    FID+IV P
Sbjct: 395 QGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFIVEP 431



 Score = 31.9 bits (69), Expect = 2.7
 Identities = 13/32 (40%), Positives = 20/32 (62%)
 Frame = +2

Query: 557 DRIQVLENLVHCADLSNPTKPLPLYKRWVALL 652
           D+ + L  L+H AD+S+PTK   ++ RW   L
Sbjct: 357 DKPKALSLLLHAADISHPTKQWLVHSRWTKAL 388


>AJ401609-1|CAC82207.1|  516|Homo sapiens 3'5' cyclic nucleotide
           phosphodiesterase 1B2 protein.
          Length = 516

 Score = 92.7 bits (220), Expect = 1e-18
 Identities = 41/86 (47%), Positives = 61/86 (70%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G TN F + + SE A++YND SVLENHH++  F+L+Q+D  +IF+NL K +   LR +
Sbjct: 247 HTGTTNSFHIQTKSECAIVYNDRSVLENHHISSVFRLMQDDEMNIFINLTKDEFVELRAL 306

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           VI+MVL+TDMS H   +  +KT +++
Sbjct: 307 VIEMVLATDMSCHFQQVKTMKTALQQ 332



 Score = 57.6 bits (133), Expect = 5e-08
 Identities = 27/84 (32%), Positives = 46/84 (54%), Gaps = 1/84 (1%)
 Frame = +1

Query: 7   VAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIR-DNPFHNSLHAADVTQSTNVLLNTP 183
           + +   T   L++  +IP    ++F   LE  Y +  NP+HN +HAADVTQ+ +  L   
Sbjct: 163 IVFELLTRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRT 222

Query: 184 ALNAVFTPLEVCAALFAACVHDVD 255
            +    + +E+ A +FAA +HD +
Sbjct: 223 GMVHCLSEIELLAIIFAAAIHDYE 246



 Score = 40.3 bits (90), Expect = 0.008
 Identities = 16/37 (43%), Positives = 24/37 (64%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHP 783
           +GD+E E G+  SP+CDR +  + +    FID+IV P
Sbjct: 375 QGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFIVEP 411



 Score = 31.9 bits (69), Expect = 2.7
 Identities = 13/32 (40%), Positives = 20/32 (62%)
 Frame = +2

Query: 557 DRIQVLENLVHCADLSNPTKPLPLYKRWVALL 652
           D+ + L  L+H AD+S+PTK   ++ RW   L
Sbjct: 337 DKPKALSLLLHAADISHPTKQWLVHSRWTKAL 368


>BC075822-1|AAH75822.1|  829|Homo sapiens phosphodiesterase 8A
           protein.
          Length = 829

 Score = 92.3 bits (219), Expect = 2e-18
 Identities = 41/74 (55%), Positives = 58/74 (78%), Gaps = 1/74 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQ-NDGCDIFVNLHKKQRQTLRK 431
           HPG TN FL N+ SELA++YND +VLE+HH A+AF+L   +D C+IF N+ +   +TLR+
Sbjct: 600 HPGRTNSFLCNAGSELAILYNDTAVLESHHAALAFQLTTGDDKCNIFKNMERNDYRTLRQ 659

Query: 432 MVIDMVLSTDMSKH 473
            +IDMVL+T+M+KH
Sbjct: 660 GIIDMVLATEMTKH 673



 Score = 54.4 bits (125), Expect = 4e-07
 Identities = 24/63 (38%), Positives = 36/63 (57%)
 Frame = +1

Query: 67  TFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVH 246
           T  ++   +E +Y   NP+HNS H+ADV  +T   L+   +     P++  AAL AA +H
Sbjct: 537 TLRSWLQIIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPIDEVAALIAATIH 596

Query: 247 DVD 255
           DVD
Sbjct: 597 DVD 599



 Score = 33.1 bits (72), Expect = 1.2
 Identities = 17/51 (33%), Positives = 25/51 (49%)
 Frame = +2

Query: 494 EDDGRTKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVA 646
           E++G T K       +L    +R  +   L+ CAD+SNP +PL     W A
Sbjct: 692 EENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAA 742


>BC060762-1|AAH60762.1|  829|Homo sapiens phosphodiesterase 8A
           protein.
          Length = 829

 Score = 92.3 bits (219), Expect = 2e-18
 Identities = 41/74 (55%), Positives = 58/74 (78%), Gaps = 1/74 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQ-NDGCDIFVNLHKKQRQTLRK 431
           HPG TN FL N+ SELA++YND +VLE+HH A+AF+L   +D C+IF N+ +   +TLR+
Sbjct: 600 HPGRTNSFLCNAGSELAILYNDTAVLESHHAALAFQLTTGDDKCNIFKNMERNDYRTLRQ 659

Query: 432 MVIDMVLSTDMSKH 473
            +IDMVL+T+M+KH
Sbjct: 660 GIIDMVLATEMTKH 673



 Score = 54.4 bits (125), Expect = 4e-07
 Identities = 24/63 (38%), Positives = 36/63 (57%)
 Frame = +1

Query: 67  TFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVH 246
           T  ++   +E +Y   NP+HNS H+ADV  +T   L+   +     P++  AAL AA +H
Sbjct: 537 TLRSWLQIIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPIDEVAALIAATIH 596

Query: 247 DVD 255
           DVD
Sbjct: 597 DVD 599



 Score = 33.1 bits (72), Expect = 1.2
 Identities = 17/51 (33%), Positives = 25/51 (49%)
 Frame = +2

Query: 494 EDDGRTKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVA 646
           E++G T K       +L    +R  +   L+ CAD+SNP +PL     W A
Sbjct: 692 EENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAA 742


>BC048317-1|AAH48317.1|  305|Homo sapiens PDE8A protein protein.
          Length = 305

 Score = 92.3 bits (219), Expect = 2e-18
 Identities = 41/74 (55%), Positives = 58/74 (78%), Gaps = 1/74 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQ-NDGCDIFVNLHKKQRQTLRK 431
           HPG TN FL N+ SELA++YND +VLE+HH A+AF+L   +D C+IF N+ +   +TLR+
Sbjct: 76  HPGRTNSFLCNAGSELAILYNDTAVLESHHAALAFQLTTGDDKCNIFKNMERNDYRTLRQ 135

Query: 432 MVIDMVLSTDMSKH 473
            +IDMVL+T+M+KH
Sbjct: 136 GIIDMVLATEMTKH 149



 Score = 54.4 bits (125), Expect = 4e-07
 Identities = 24/63 (38%), Positives = 36/63 (57%)
 Frame = +1

Query: 67  TFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVH 246
           T  ++   +E +Y   NP+HNS H+ADV  +T   L+   +     P++  AAL AA +H
Sbjct: 13  TLRSWLQIIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPIDEVAALIAATIH 72

Query: 247 DVD 255
           DVD
Sbjct: 73  DVD 75



 Score = 33.1 bits (72), Expect = 1.2
 Identities = 17/51 (33%), Positives = 25/51 (49%)
 Frame = +2

Query: 494 EDDGRTKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVA 646
           E++G T K       +L    +R  +   L+ CAD+SNP +PL     W A
Sbjct: 168 EENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAA 218


>AF388187-1|AAL18614.1|  582|Homo sapiens cAMP phosphodiesterase
           PDE8A5 protein.
          Length = 582

 Score = 92.3 bits (219), Expect = 2e-18
 Identities = 41/74 (55%), Positives = 58/74 (78%), Gaps = 1/74 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQ-NDGCDIFVNLHKKQRQTLRK 431
           HPG TN FL N+ SELA++YND +VLE+HH A+AF+L   +D C+IF N+ +   +TLR+
Sbjct: 353 HPGRTNSFLCNAGSELAILYNDTAVLESHHAALAFQLTTGDDKCNIFKNMERNDYRTLRQ 412

Query: 432 MVIDMVLSTDMSKH 473
            +IDMVL+T+M+KH
Sbjct: 413 GIIDMVLATEMTKH 426



 Score = 54.4 bits (125), Expect = 4e-07
 Identities = 24/63 (38%), Positives = 36/63 (57%)
 Frame = +1

Query: 67  TFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVH 246
           T  ++   +E +Y   NP+HNS H+ADV  +T   L+   +     P++  AAL AA +H
Sbjct: 290 TLRSWLQIIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPIDEVAALIAATIH 349

Query: 247 DVD 255
           DVD
Sbjct: 350 DVD 352



 Score = 33.1 bits (72), Expect = 1.2
 Identities = 17/51 (33%), Positives = 25/51 (49%)
 Frame = +2

Query: 494 EDDGRTKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVA 646
           E++G T K       +L    +R  +   L+ CAD+SNP +PL     W A
Sbjct: 445 EENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAA 495


>AF388186-1|AAL18613.1|  582|Homo sapiens cAMP phosphodiesterase
           PDE8A4 protein.
          Length = 582

 Score = 92.3 bits (219), Expect = 2e-18
 Identities = 41/74 (55%), Positives = 58/74 (78%), Gaps = 1/74 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQ-NDGCDIFVNLHKKQRQTLRK 431
           HPG TN FL N+ SELA++YND +VLE+HH A+AF+L   +D C+IF N+ +   +TLR+
Sbjct: 353 HPGRTNSFLCNAGSELAILYNDTAVLESHHAALAFQLTTGDDKCNIFKNMERNDYRTLRQ 412

Query: 432 MVIDMVLSTDMSKH 473
            +IDMVL+T+M+KH
Sbjct: 413 GIIDMVLATEMTKH 426



 Score = 54.4 bits (125), Expect = 4e-07
 Identities = 24/63 (38%), Positives = 36/63 (57%)
 Frame = +1

Query: 67  TFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVH 246
           T  ++   +E +Y   NP+HNS H+ADV  +T   L+   +     P++  AAL AA +H
Sbjct: 290 TLRSWLQIIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPIDEVAALIAATIH 349

Query: 247 DVD 255
           DVD
Sbjct: 350 DVD 352



 Score = 33.1 bits (72), Expect = 1.2
 Identities = 17/51 (33%), Positives = 25/51 (49%)
 Frame = +2

Query: 494 EDDGRTKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVA 646
           E++G T K       +L    +R  +   L+ CAD+SNP +PL     W A
Sbjct: 445 EENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAA 495


>AF388185-1|AAL18612.1|  449|Homo sapiens cAMP phosphodiesterase
           PDE8A3 protein.
          Length = 449

 Score = 92.3 bits (219), Expect = 2e-18
 Identities = 41/74 (55%), Positives = 58/74 (78%), Gaps = 1/74 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQ-NDGCDIFVNLHKKQRQTLRK 431
           HPG TN FL N+ SELA++YND +VLE+HH A+AF+L   +D C+IF N+ +   +TLR+
Sbjct: 220 HPGRTNSFLCNAGSELAILYNDTAVLESHHAALAFQLTTGDDKCNIFKNMERNDYRTLRQ 279

Query: 432 MVIDMVLSTDMSKH 473
            +IDMVL+T+M+KH
Sbjct: 280 GIIDMVLATEMTKH 293



 Score = 54.4 bits (125), Expect = 4e-07
 Identities = 24/63 (38%), Positives = 36/63 (57%)
 Frame = +1

Query: 67  TFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVH 246
           T  ++   +E +Y   NP+HNS H+ADV  +T   L+   +     P++  AAL AA +H
Sbjct: 157 TLRSWLQIIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPIDEVAALIAATIH 216

Query: 247 DVD 255
           DVD
Sbjct: 217 DVD 219



 Score = 33.1 bits (72), Expect = 1.2
 Identities = 17/51 (33%), Positives = 25/51 (49%)
 Frame = +2

Query: 494 EDDGRTKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVA 646
           E++G T K       +L    +R  +   L+ CAD+SNP +PL     W A
Sbjct: 312 EENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAA 362


>AF388184-1|AAL18611.1|  783|Homo sapiens cAMP phosphodiesterase
           PDE8A2 protein.
          Length = 783

 Score = 92.3 bits (219), Expect = 2e-18
 Identities = 41/74 (55%), Positives = 58/74 (78%), Gaps = 1/74 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQ-NDGCDIFVNLHKKQRQTLRK 431
           HPG TN FL N+ SELA++YND +VLE+HH A+AF+L   +D C+IF N+ +   +TLR+
Sbjct: 554 HPGRTNSFLCNAGSELAILYNDTAVLESHHAALAFQLTTGDDKCNIFKNMERNDYRTLRQ 613

Query: 432 MVIDMVLSTDMSKH 473
            +IDMVL+T+M+KH
Sbjct: 614 GIIDMVLATEMTKH 627



 Score = 54.4 bits (125), Expect = 4e-07
 Identities = 24/63 (38%), Positives = 36/63 (57%)
 Frame = +1

Query: 67  TFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVH 246
           T  ++   +E +Y   NP+HNS H+ADV  +T   L+   +     P++  AAL AA +H
Sbjct: 491 TLRSWLQIIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPIDEVAALIAATIH 550

Query: 247 DVD 255
           DVD
Sbjct: 551 DVD 553



 Score = 33.1 bits (72), Expect = 1.2
 Identities = 17/51 (33%), Positives = 25/51 (49%)
 Frame = +2

Query: 494 EDDGRTKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVA 646
           E++G T K       +L    +R  +   L+ CAD+SNP +PL     W A
Sbjct: 646 EENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAA 696


>AF388183-1|AAL18610.1|  829|Homo sapiens cAMP phosphodiesterase
           PDE8A1 protein.
          Length = 829

 Score = 92.3 bits (219), Expect = 2e-18
 Identities = 41/74 (55%), Positives = 58/74 (78%), Gaps = 1/74 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQ-NDGCDIFVNLHKKQRQTLRK 431
           HPG TN FL N+ SELA++YND +VLE+HH A+AF+L   +D C+IF N+ +   +TLR+
Sbjct: 600 HPGRTNSFLCNAGSELAILYNDTAVLESHHAALAFQLTTGDDKCNIFKNMERNDYRTLRQ 659

Query: 432 MVIDMVLSTDMSKH 473
            +IDMVL+T+M+KH
Sbjct: 660 GIIDMVLATEMTKH 673



 Score = 54.4 bits (125), Expect = 4e-07
 Identities = 24/63 (38%), Positives = 36/63 (57%)
 Frame = +1

Query: 67  TFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVH 246
           T  ++   +E +Y   NP+HNS H+ADV  +T   L+   +     P++  AAL AA +H
Sbjct: 537 TLRSWLQIIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPIDEVAALIAATIH 596

Query: 247 DVD 255
           DVD
Sbjct: 597 DVD 599



 Score = 33.1 bits (72), Expect = 1.2
 Identities = 17/51 (33%), Positives = 25/51 (49%)
 Frame = +2

Query: 494 EDDGRTKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVA 646
           E++G T K       +L    +R  +   L+ CAD+SNP +PL     W A
Sbjct: 692 EENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAA 742


>AF332653-1|AAK57641.1|  829|Homo sapiens cAMP-specific cyclic
           nucleotide phosphodiesterase PDE8A1 protein.
          Length = 829

 Score = 92.3 bits (219), Expect = 2e-18
 Identities = 41/74 (55%), Positives = 58/74 (78%), Gaps = 1/74 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQ-NDGCDIFVNLHKKQRQTLRK 431
           HPG TN FL N+ SELA++YND +VLE+HH A+AF+L   +D C+IF N+ +   +TLR+
Sbjct: 600 HPGRTNSFLCNAGSELAILYNDTAVLESHHAALAFQLTTGDDKCNIFKNMERNDYRTLRQ 659

Query: 432 MVIDMVLSTDMSKH 473
            +IDMVL+T+M+KH
Sbjct: 660 GIIDMVLATEMTKH 673



 Score = 54.4 bits (125), Expect = 4e-07
 Identities = 24/63 (38%), Positives = 36/63 (57%)
 Frame = +1

Query: 67  TFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVH 246
           T  ++   +E +Y   NP+HNS H+ADV  +T   L+   +     P++  AAL AA +H
Sbjct: 537 TLRSWLQIIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPIDEVAALIAATIH 596

Query: 247 DVD 255
           DVD
Sbjct: 597 DVD 599



 Score = 33.1 bits (72), Expect = 1.2
 Identities = 17/51 (33%), Positives = 25/51 (49%)
 Frame = +2

Query: 494 EDDGRTKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVA 646
           E++G T K       +L    +R  +   L+ CAD+SNP +PL     W A
Sbjct: 692 EENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAA 742


>AF056490-1|AAC39763.1|  713|Homo sapiens cAMP-specific
           phosphodiesterase 8A protein.
          Length = 713

 Score = 92.3 bits (219), Expect = 2e-18
 Identities = 41/74 (55%), Positives = 58/74 (78%), Gaps = 1/74 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQ-NDGCDIFVNLHKKQRQTLRK 431
           HPG TN FL N+ SELA++YND +VLE+HH A+AF+L   +D C+IF N+ +   +TLR+
Sbjct: 484 HPGRTNSFLCNAGSELAILYNDTAVLESHHAALAFQLTTGDDKCNIFKNMERNDYRTLRQ 543

Query: 432 MVIDMVLSTDMSKH 473
            +IDMVL+T+M+KH
Sbjct: 544 GIIDMVLATEMTKH 557



 Score = 54.4 bits (125), Expect = 4e-07
 Identities = 24/63 (38%), Positives = 36/63 (57%)
 Frame = +1

Query: 67  TFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVH 246
           T  ++   +E +Y   NP+HNS H+ADV  +T   L+   +     P++  AAL AA +H
Sbjct: 421 TLRSWLQIIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPIDEVAALIAATIH 480

Query: 247 DVD 255
           DVD
Sbjct: 481 DVD 483



 Score = 33.1 bits (72), Expect = 1.2
 Identities = 17/51 (33%), Positives = 25/51 (49%)
 Frame = +2

Query: 494 EDDGRTKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVA 646
           E++G T K       +L    +R  +   L+ CAD+SNP +PL     W A
Sbjct: 576 EENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAA 626


>BC047627-1|AAH47627.1|  241|Homo sapiens PDE8B protein protein.
          Length = 241

 Score = 91.5 bits (217), Expect = 3e-18
 Identities = 41/74 (55%), Positives = 57/74 (77%), Gaps = 1/74 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQND-GCDIFVNLHKKQRQTLRK 431
           HPG TN FL N+ SELA++YND +VLE+HH A+AF+L   D  C+IF N+ +   +TLR+
Sbjct: 15  HPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQ 74

Query: 432 MVIDMVLSTDMSKH 473
            +IDMVL+T+M+KH
Sbjct: 75  AIIDMVLATEMTKH 88


>BC035144-1|AAH35144.1|  385|Homo sapiens PDE8B protein protein.
          Length = 385

 Score = 91.5 bits (217), Expect = 3e-18
 Identities = 41/74 (55%), Positives = 57/74 (77%), Gaps = 1/74 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQND-GCDIFVNLHKKQRQTLRK 431
           HPG TN FL N+ SELA++YND +VLE+HH A+AF+L   D  C+IF N+ +   +TLR+
Sbjct: 159 HPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQ 218

Query: 432 MVIDMVLSTDMSKH 473
            +IDMVL+T+M+KH
Sbjct: 219 AIIDMVLATEMTKH 232



 Score = 50.4 bits (115), Expect = 7e-06
 Identities = 26/63 (41%), Positives = 33/63 (52%)
 Frame = +1

Query: 67  TFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVH 246
           T  A+   +E +Y   N +HNS HAADV  +T   L    +      L+  AAL AA VH
Sbjct: 96  TLRAWFQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVH 155

Query: 247 DVD 255
           DVD
Sbjct: 156 DVD 158



 Score = 31.1 bits (67), Expect = 4.7
 Identities = 16/63 (25%), Positives = 33/63 (52%)
 Frame = +2

Query: 452 LDRYVETHESAGGSEDDGRTKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLY 631
           ++++V +      +E +G   +   +G   L+N   +I +   ++ CAD++NP +PL L 
Sbjct: 236 VNKFVNSINKPMAAEIEGSDCECNPAGKNFLEN---QILIKRMMIKCADVANPCRPLDLC 292

Query: 632 KRW 640
             W
Sbjct: 293 IEW 295


>AY423729-1|AAS00492.1|  350|Homo sapiens proliferation-inducing
           gene 22 protein protein.
          Length = 350

 Score = 91.5 bits (217), Expect = 3e-18
 Identities = 41/74 (55%), Positives = 57/74 (77%), Gaps = 1/74 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQND-GCDIFVNLHKKQRQTLRK 431
           HPG TN FL N+ SELA++YND +VLE+HH A+AF+L   D  C+IF N+ +   +TLR+
Sbjct: 124 HPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQ 183

Query: 432 MVIDMVLSTDMSKH 473
            +IDMVL+T+M+KH
Sbjct: 184 AIIDMVLATEMTKH 197



 Score = 50.4 bits (115), Expect = 7e-06
 Identities = 26/63 (41%), Positives = 33/63 (52%)
 Frame = +1

Query: 67  TFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVH 246
           T  A+   +E +Y   N +HNS HAADV  +T   L    +      L+  AAL AA VH
Sbjct: 61  TLRAWFQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVH 120

Query: 247 DVD 255
           DVD
Sbjct: 121 DVD 123


>AY129950-3|AAN71727.1|  788|Homo sapiens cAMP-specific
           phosphodiesterase 8B3 protein.
          Length = 788

 Score = 91.5 bits (217), Expect = 3e-18
 Identities = 41/74 (55%), Positives = 57/74 (77%), Gaps = 1/74 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQND-GCDIFVNLHKKQRQTLRK 431
           HPG TN FL N+ SELA++YND +VLE+HH A+AF+L   D  C+IF N+ +   +TLR+
Sbjct: 562 HPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQ 621

Query: 432 MVIDMVLSTDMSKH 473
            +IDMVL+T+M+KH
Sbjct: 622 AIIDMVLATEMTKH 635



 Score = 50.4 bits (115), Expect = 7e-06
 Identities = 26/63 (41%), Positives = 33/63 (52%)
 Frame = +1

Query: 67  TFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVH 246
           T  A+   +E +Y   N +HNS HAADV  +T   L    +      L+  AAL AA VH
Sbjct: 499 TLRAWFQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVH 558

Query: 247 DVD 255
           DVD
Sbjct: 559 DVD 561


>AY129950-2|AAN71726.1|  838|Homo sapiens cAMP-specific
           phosphodiesterase 8B2 protein.
          Length = 838

 Score = 91.5 bits (217), Expect = 3e-18
 Identities = 41/74 (55%), Positives = 57/74 (77%), Gaps = 1/74 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQND-GCDIFVNLHKKQRQTLRK 431
           HPG TN FL N+ SELA++YND +VLE+HH A+AF+L   D  C+IF N+ +   +TLR+
Sbjct: 612 HPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQ 671

Query: 432 MVIDMVLSTDMSKH 473
            +IDMVL+T+M+KH
Sbjct: 672 AIIDMVLATEMTKH 685



 Score = 50.4 bits (115), Expect = 7e-06
 Identities = 26/63 (41%), Positives = 33/63 (52%)
 Frame = +1

Query: 67  TFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVH 246
           T  A+   +E +Y   N +HNS HAADV  +T   L    +      L+  AAL AA VH
Sbjct: 549 TLRAWFQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVH 608

Query: 247 DVD 255
           DVD
Sbjct: 609 DVD 611


>AY129950-1|AAN71725.1|  885|Homo sapiens cAMP-specific
           phosphodiesterase 8B1 protein.
          Length = 885

 Score = 91.5 bits (217), Expect = 3e-18
 Identities = 41/74 (55%), Positives = 57/74 (77%), Gaps = 1/74 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQND-GCDIFVNLHKKQRQTLRK 431
           HPG TN FL N+ SELA++YND +VLE+HH A+AF+L   D  C+IF N+ +   +TLR+
Sbjct: 659 HPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQ 718

Query: 432 MVIDMVLSTDMSKH 473
            +IDMVL+T+M+KH
Sbjct: 719 AIIDMVLATEMTKH 732



 Score = 50.4 bits (115), Expect = 7e-06
 Identities = 26/63 (41%), Positives = 33/63 (52%)
 Frame = +1

Query: 67  TFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVH 246
           T  A+   +E +Y   N +HNS HAADV  +T   L    +      L+  AAL AA VH
Sbjct: 596 TLRAWFQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVH 655

Query: 247 DVD 255
           DVD
Sbjct: 656 DVD 658


>AY129949-1|AAN71724.1|  788|Homo sapiens cAMP-specific
           phosphodiesterase 8B3 protein.
          Length = 788

 Score = 91.5 bits (217), Expect = 3e-18
 Identities = 41/74 (55%), Positives = 57/74 (77%), Gaps = 1/74 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQND-GCDIFVNLHKKQRQTLRK 431
           HPG TN FL N+ SELA++YND +VLE+HH A+AF+L   D  C+IF N+ +   +TLR+
Sbjct: 562 HPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQ 621

Query: 432 MVIDMVLSTDMSKH 473
            +IDMVL+T+M+KH
Sbjct: 622 AIIDMVLATEMTKH 635



 Score = 50.4 bits (115), Expect = 7e-06
 Identities = 26/63 (41%), Positives = 33/63 (52%)
 Frame = +1

Query: 67  TFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVH 246
           T  A+   +E +Y   N +HNS HAADV  +T   L    +      L+  AAL AA VH
Sbjct: 499 TLRAWFQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVH 558

Query: 247 DVD 255
           DVD
Sbjct: 559 DVD 561


>AY129948-1|AAN71723.1|  838|Homo sapiens cAMP-specific
           phosphodiesterase 8B2 protein.
          Length = 838

 Score = 91.5 bits (217), Expect = 3e-18
 Identities = 41/74 (55%), Positives = 57/74 (77%), Gaps = 1/74 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQND-GCDIFVNLHKKQRQTLRK 431
           HPG TN FL N+ SELA++YND +VLE+HH A+AF+L   D  C+IF N+ +   +TLR+
Sbjct: 612 HPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQ 671

Query: 432 MVIDMVLSTDMSKH 473
            +IDMVL+T+M+KH
Sbjct: 672 AIIDMVLATEMTKH 685



 Score = 50.4 bits (115), Expect = 7e-06
 Identities = 26/63 (41%), Positives = 33/63 (52%)
 Frame = +1

Query: 67  TFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVH 246
           T  A+   +E +Y   N +HNS HAADV  +T   L    +      L+  AAL AA VH
Sbjct: 549 TLRAWFQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVH 608

Query: 247 DVD 255
           DVD
Sbjct: 609 DVD 611


>AL831924-1|CAD38584.1|  843|Homo sapiens hypothetical protein
           protein.
          Length = 843

 Score = 91.5 bits (217), Expect = 3e-18
 Identities = 41/74 (55%), Positives = 57/74 (77%), Gaps = 1/74 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQND-GCDIFVNLHKKQRQTLRK 431
           HPG TN FL N+ SELA++YND +VLE+HH A+AF+L   D  C+IF N+ +   +TLR+
Sbjct: 617 HPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQ 676

Query: 432 MVIDMVLSTDMSKH 473
            +IDMVL+T+M+KH
Sbjct: 677 AIIDMVLATEMTKH 690



 Score = 50.4 bits (115), Expect = 7e-06
 Identities = 26/63 (41%), Positives = 33/63 (52%)
 Frame = +1

Query: 67  TFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVH 246
           T  A+   +E +Y   N +HNS HAADV  +T   L    +      L+  AAL AA VH
Sbjct: 554 TLRAWFQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVH 613

Query: 247 DVD 255
           DVD
Sbjct: 614 DVD 616


>AF079529-1|AAC69564.2|  885|Homo sapiens cAMP-specific
           phosphodiesterase 8B1 protein.
          Length = 885

 Score = 91.5 bits (217), Expect = 3e-18
 Identities = 41/74 (55%), Positives = 57/74 (77%), Gaps = 1/74 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQND-GCDIFVNLHKKQRQTLRK 431
           HPG TN FL N+ SELA++YND +VLE+HH A+AF+L   D  C+IF N+ +   +TLR+
Sbjct: 659 HPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQ 718

Query: 432 MVIDMVLSTDMSKH 473
            +IDMVL+T+M+KH
Sbjct: 719 AIIDMVLATEMTKH 732



 Score = 50.4 bits (115), Expect = 7e-06
 Identities = 26/63 (41%), Positives = 33/63 (52%)
 Frame = +1

Query: 67  TFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVH 246
           T  A+   +E +Y   N +HNS HAADV  +T   L    +      L+  AAL AA VH
Sbjct: 596 TLRAWFQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVH 655

Query: 247 DVD 255
           DVD
Sbjct: 656 DVD 658


>AB085827-1|BAC53765.1|  865|Homo sapiens phosphodiesterase 8B4
           protein.
          Length = 865

 Score = 91.5 bits (217), Expect = 3e-18
 Identities = 41/74 (55%), Positives = 57/74 (77%), Gaps = 1/74 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQND-GCDIFVNLHKKQRQTLRK 431
           HPG TN FL N+ SELA++YND +VLE+HH A+AF+L   D  C+IF N+ +   +TLR+
Sbjct: 639 HPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQ 698

Query: 432 MVIDMVLSTDMSKH 473
            +IDMVL+T+M+KH
Sbjct: 699 AIIDMVLATEMTKH 712



 Score = 50.4 bits (115), Expect = 7e-06
 Identities = 26/63 (41%), Positives = 33/63 (52%)
 Frame = +1

Query: 67  TFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVH 246
           T  A+   +E +Y   N +HNS HAADV  +T   L    +      L+  AAL AA VH
Sbjct: 576 TLRAWFQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVH 635

Query: 247 DVD 255
           DVD
Sbjct: 636 DVD 638


>AB085826-1|BAC53764.1|  830|Homo sapiens phosphodiesterase 8B3
           protein.
          Length = 830

 Score = 91.5 bits (217), Expect = 3e-18
 Identities = 41/74 (55%), Positives = 57/74 (77%), Gaps = 1/74 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQND-GCDIFVNLHKKQRQTLRK 431
           HPG TN FL N+ SELA++YND +VLE+HH A+AF+L   D  C+IF N+ +   +TLR+
Sbjct: 604 HPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQ 663

Query: 432 MVIDMVLSTDMSKH 473
            +IDMVL+T+M+KH
Sbjct: 664 AIIDMVLATEMTKH 677



 Score = 50.4 bits (115), Expect = 7e-06
 Identities = 26/63 (41%), Positives = 33/63 (52%)
 Frame = +1

Query: 67  TFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVH 246
           T  A+   +E +Y   N +HNS HAADV  +T   L    +      L+  AAL AA VH
Sbjct: 541 TLRAWFQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVH 600

Query: 247 DVD 255
           DVD
Sbjct: 601 DVD 603


>AB085825-1|BAC53763.1|  788|Homo sapiens phosphodiestearse 8B2
           protein.
          Length = 788

 Score = 91.5 bits (217), Expect = 3e-18
 Identities = 41/74 (55%), Positives = 57/74 (77%), Gaps = 1/74 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQND-GCDIFVNLHKKQRQTLRK 431
           HPG TN FL N+ SELA++YND +VLE+HH A+AF+L   D  C+IF N+ +   +TLR+
Sbjct: 562 HPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQ 621

Query: 432 MVIDMVLSTDMSKH 473
            +IDMVL+T+M+KH
Sbjct: 622 AIIDMVLATEMTKH 635



 Score = 50.4 bits (115), Expect = 7e-06
 Identities = 26/63 (41%), Positives = 33/63 (52%)
 Frame = +1

Query: 67  TFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVH 246
           T  A+   +E +Y   N +HNS HAADV  +T   L    +      L+  AAL AA VH
Sbjct: 499 TLRAWFQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVH 558

Query: 247 DVD 255
           DVD
Sbjct: 559 DVD 561


>AB085824-1|BAC53762.1|  885|Homo sapiens phosphodiesterase 8B1
           protein.
          Length = 885

 Score = 91.5 bits (217), Expect = 3e-18
 Identities = 41/74 (55%), Positives = 57/74 (77%), Gaps = 1/74 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQND-GCDIFVNLHKKQRQTLRK 431
           HPG TN FL N+ SELA++YND +VLE+HH A+AF+L   D  C+IF N+ +   +TLR+
Sbjct: 659 HPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQ 718

Query: 432 MVIDMVLSTDMSKH 473
            +IDMVL+T+M+KH
Sbjct: 719 AIIDMVLATEMTKH 732



 Score = 50.4 bits (115), Expect = 7e-06
 Identities = 26/63 (41%), Positives = 33/63 (52%)
 Frame = +1

Query: 67  TFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVH 246
           T  A+   +E +Y   N +HNS HAADV  +T   L    +      L+  AAL AA VH
Sbjct: 596 TLRAWFQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVH 655

Query: 247 DVD 255
           DVD
Sbjct: 656 DVD 658


>L20968-1|AAA03591.1|  251|Homo sapiens phosphodiesterase protein.
          Length = 251

 Score = 91.1 bits (216), Expect = 4e-18
 Identities = 44/58 (75%), Positives = 50/58 (86%)
 Frame = +3

Query: 345 LAVAFKLLQNDGCDIFVNLHKKQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVERRK 518
           LAV FKLLQ + CDIF NL  KQR +LR+MVIDMVL+TDMSKHM+LLADLKTMVE +K
Sbjct: 1   LAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKK 58



 Score = 86.6 bits (205), Expect = 9e-17
 Identities = 46/86 (53%), Positives = 54/86 (62%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV   GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W   +            
Sbjct: 56  TKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRER 115

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
            +   IS  C       +EKSQVG +
Sbjct: 116 ESGLDISPMC-DKHTASVEKSQVGFI 140



 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 26/39 (66%), Positives = 31/39 (79%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE G+DISPMCD+H A++ K    FIDYI HPLW
Sbjct: 110 QGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLW 148


>U40370-1|AAC50436.1|  535|Homo sapiens 3',5' cyclic nucleotide
           phosphodiesterase protein.
          Length = 535

 Score = 89.4 bits (212), Expect = 1e-17
 Identities = 37/86 (43%), Positives = 61/86 (70%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G TN F + + S++A++YND SVLENHH++ A++L+Q +  +I +NL K   + LR +
Sbjct: 263 HTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLRNL 322

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           VI+MVLSTDMS H   + +++  +++
Sbjct: 323 VIEMVLSTDMSGHFQQIKNIRNSLQQ 348



 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
 Frame = +1

Query: 13  YTAFTSRELLTTLQIPARTFLAFAVTLEEHYIR-DNPFHNSLHAADVTQSTNVLLNTPAL 189
           Y  FT  +L+   +IP    + FA  LE  Y +  NP+HN +HAADVTQ+ + ++    +
Sbjct: 181 YELFTRYDLINRFKIPVSCLITFAEALEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGI 240

Query: 190 NAVFTPLEVCAALFAACVHDVD 255
               T LE+ A +FAA +HD +
Sbjct: 241 MHWLTELEILAMVFAAAIHDYE 262



 Score = 40.7 bits (91), Expect = 0.006
 Identities = 16/37 (43%), Positives = 24/37 (64%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHP 783
           +GD+E E G+  SP+CDR +  + +    FID+IV P
Sbjct: 391 QGDKEAELGLPFSPLCDRKSTMVAQSQIGFIDFIVEP 427



 Score = 31.5 bits (68), Expect = 3.6
 Identities = 12/32 (37%), Positives = 19/32 (59%)
 Frame = +2

Query: 557 DRIQVLENLVHCADLSNPTKPLPLYKRWVALL 652
           DR + +  ++H AD+S+P K   L+ RW   L
Sbjct: 353 DRAKTMSLILHAADISHPAKSWKLHYRWTMAL 384


>BC022480-1|AAH22480.1|  545|Homo sapiens phosphodiesterase 1A,
           calmodulin-dependent protein.
          Length = 545

 Score = 89.4 bits (212), Expect = 1e-17
 Identities = 37/86 (43%), Positives = 61/86 (70%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G TN F + + S++A++YND SVLENHH++ A++L+Q +  +I +NL K   + LR +
Sbjct: 263 HTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLRNL 322

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           VI+MVLSTDMS H   + +++  +++
Sbjct: 323 VIEMVLSTDMSGHFQQIKNIRNSLQQ 348



 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
 Frame = +1

Query: 13  YTAFTSRELLTTLQIPARTFLAFAVTLEEHYIR-DNPFHNSLHAADVTQSTNVLLNTPAL 189
           Y  FT  +L+   +IP    + FA  LE  Y +  NP+HN +HAADVTQ+ + ++    +
Sbjct: 181 YELFTRYDLINRFKIPVSCLITFAEALEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGI 240

Query: 190 NAVFTPLEVCAALFAACVHDVD 255
               T LE+ A +FAA +HD +
Sbjct: 241 MHWLTELEILAMVFAAAIHDYE 262



 Score = 40.7 bits (91), Expect = 0.006
 Identities = 16/37 (43%), Positives = 24/37 (64%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHP 783
           +GD+E E G+  SP+CDR +  + +    FID+IV P
Sbjct: 391 QGDKEAELGLPFSPLCDRKSTMVAQSQIGFIDFIVEP 427



 Score = 31.5 bits (68), Expect = 3.6
 Identities = 12/32 (37%), Positives = 19/32 (59%)
 Frame = +2

Query: 557 DRIQVLENLVHCADLSNPTKPLPLYKRWVALL 652
           DR + +  ++H AD+S+P K   L+ RW   L
Sbjct: 353 DRAKTMSLILHAADISHPAKSWKLHYRWTMAL 384


>AL110263-1|CAB53703.1|  519|Homo sapiens hypothetical protein
           protein.
          Length = 519

 Score = 89.4 bits (212), Expect = 1e-17
 Identities = 37/86 (43%), Positives = 61/86 (70%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G TN F + + S++A++YND SVLENHH++ A++L+Q +  +I +NL K   + LR +
Sbjct: 247 HTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLRNL 306

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           VI+MVLSTDMS H   + +++  +++
Sbjct: 307 VIEMVLSTDMSGHFQQIKNIRNSLQQ 332



 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
 Frame = +1

Query: 13  YTAFTSRELLTTLQIPARTFLAFAVTLEEHYIR-DNPFHNSLHAADVTQSTNVLLNTPAL 189
           Y  FT  +L+   +IP    + FA  LE  Y +  NP+HN +HAADVTQ+ + ++    +
Sbjct: 165 YELFTRYDLINRFKIPVSCLITFAEALEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGI 224

Query: 190 NAVFTPLEVCAALFAACVHDVD 255
               T LE+ A +FAA +HD +
Sbjct: 225 MHWLTELEILAMVFAAAIHDYE 246



 Score = 40.7 bits (91), Expect = 0.006
 Identities = 16/37 (43%), Positives = 24/37 (64%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHP 783
           +GD+E E G+  SP+CDR +  + +    FID+IV P
Sbjct: 375 QGDKEAELGLPFSPLCDRKSTMVAQSQIGFIDFIVEP 411



 Score = 31.5 bits (68), Expect = 3.6
 Identities = 12/32 (37%), Positives = 19/32 (59%)
 Frame = +2

Query: 557 DRIQVLENLVHCADLSNPTKPLPLYKRWVALL 652
           DR + +  ++H AD+S+P K   L+ RW   L
Sbjct: 337 DRAKTMSLILHAADISHPAKSWKLHYRWTMAL 368


>AJ401610-1|CAC82208.1|  519|Homo sapiens 3'5' cyclic nucleotide
           phosphodiesterase 1A5 protein.
          Length = 519

 Score = 89.4 bits (212), Expect = 1e-17
 Identities = 37/86 (43%), Positives = 61/86 (70%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G TN F + + S++A++YND SVLENHH++ A++L+Q +  +I +NL K   + LR +
Sbjct: 247 HTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLRNL 306

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           VI+MVLSTDMS H   + +++  +++
Sbjct: 307 VIEMVLSTDMSGHFQQIKNIRNSLQQ 332



 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
 Frame = +1

Query: 13  YTAFTSRELLTTLQIPARTFLAFAVTLEEHYIR-DNPFHNSLHAADVTQSTNVLLNTPAL 189
           Y  FT  +L+   +IP    + FA  LE  Y +  NP+HN +HAADVTQ+ + ++    +
Sbjct: 165 YELFTRYDLINRFKIPVSCLITFAEALEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGI 224

Query: 190 NAVFTPLEVCAALFAACVHDVD 255
               T LE+ A +FAA +HD +
Sbjct: 225 MHWLTELEILAMVFAAAIHDYE 246



 Score = 40.7 bits (91), Expect = 0.006
 Identities = 16/37 (43%), Positives = 24/37 (64%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHP 783
           +GD+E E G+  SP+CDR +  + +    FID+IV P
Sbjct: 375 QGDKEAELGLPFSPLCDRKSTMVAQSQIGFIDFIVEP 411



 Score = 31.5 bits (68), Expect = 3.6
 Identities = 12/32 (37%), Positives = 19/32 (59%)
 Frame = +2

Query: 557 DRIQVLENLVHCADLSNPTKPLPLYKRWVALL 652
           DR + +  ++H AD+S+P K   L+ RW   L
Sbjct: 337 DRAKTMSLILHAADISHPAKSWKLHYRWTMAL 368


>AB038224-9|BAB20054.1|  518|Homo sapiens calmodulin-dependent
           phosphodiesterase protein.
          Length = 518

 Score = 89.4 bits (212), Expect = 1e-17
 Identities = 37/86 (43%), Positives = 61/86 (70%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G TN F + + S++A++YND SVLENHH++ A++L+Q +  +I +NL K   + LR +
Sbjct: 229 HTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLRNL 288

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           VI+MVLSTDMS H   + +++  +++
Sbjct: 289 VIEMVLSTDMSGHFQQIKNIRNSLQQ 314



 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
 Frame = +1

Query: 13  YTAFTSRELLTTLQIPARTFLAFAVTLEEHYIR-DNPFHNSLHAADVTQSTNVLLNTPAL 189
           Y  FT  +L+   +IP    + FA  LE  Y +  NP+HN +HAADVTQ+ + ++    +
Sbjct: 147 YELFTRYDLINRFKIPVSCLITFAEALEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGI 206

Query: 190 NAVFTPLEVCAALFAACVHDVD 255
               T LE+ A +FAA +HD +
Sbjct: 207 MHWLTELEILAMVFAAAIHDYE 228



 Score = 40.7 bits (91), Expect = 0.006
 Identities = 16/37 (43%), Positives = 24/37 (64%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHP 783
           +GD+E E G+  SP+CDR +  + +    FID+IV P
Sbjct: 357 QGDKEAELGLPFSPLCDRKSTMVAQSQIGFIDFIVEP 393



 Score = 31.5 bits (68), Expect = 3.6
 Identities = 12/32 (37%), Positives = 19/32 (59%)
 Frame = +2

Query: 557 DRIQVLENLVHCADLSNPTKPLPLYKRWVALL 652
           DR + +  ++H AD+S+P K   L+ RW   L
Sbjct: 319 DRAKTMSLILHAADISHPAKSWKLHYRWTMAL 350


>AB038224-8|BAB20053.1|  501|Homo sapiens calmodulin-dependent
           phosphodiesterase protein.
          Length = 501

 Score = 89.4 bits (212), Expect = 1e-17
 Identities = 37/86 (43%), Positives = 61/86 (70%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G TN F + + S++A++YND SVLENHH++ A++L+Q +  +I +NL K   + LR +
Sbjct: 229 HTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLRNL 288

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           VI+MVLSTDMS H   + +++  +++
Sbjct: 289 VIEMVLSTDMSGHFQQIKNIRNSLQQ 314



 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
 Frame = +1

Query: 13  YTAFTSRELLTTLQIPARTFLAFAVTLEEHYIR-DNPFHNSLHAADVTQSTNVLLNTPAL 189
           Y  FT  +L+   +IP    + FA  LE  Y +  NP+HN +HAADVTQ+ + ++    +
Sbjct: 147 YELFTRYDLINRFKIPVSCLITFAEALEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGI 206

Query: 190 NAVFTPLEVCAALFAACVHDVD 255
               T LE+ A +FAA +HD +
Sbjct: 207 MHWLTELEILAMVFAAAIHDYE 228



 Score = 40.7 bits (91), Expect = 0.006
 Identities = 16/37 (43%), Positives = 24/37 (64%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHP 783
           +GD+E E G+  SP+CDR +  + +    FID+IV P
Sbjct: 357 QGDKEAELGLPFSPLCDRKSTMVAQSQIGFIDFIVEP 393



 Score = 31.5 bits (68), Expect = 3.6
 Identities = 12/32 (37%), Positives = 19/32 (59%)
 Frame = +2

Query: 557 DRIQVLENLVHCADLSNPTKPLPLYKRWVALL 652
           DR + +  ++H AD+S+P K   L+ RW   L
Sbjct: 319 DRAKTMSLILHAADISHPAKSWKLHYRWTMAL 350


>AB038224-7|BAB20057.1|  511|Homo sapiens calmodulin-dependent
           phosphodiesterase protein.
          Length = 511

 Score = 89.4 bits (212), Expect = 1e-17
 Identities = 37/86 (43%), Positives = 61/86 (70%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G TN F + + S++A++YND SVLENHH++ A++L+Q +  +I +NL K   + LR +
Sbjct: 229 HTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLRNL 288

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           VI+MVLSTDMS H   + +++  +++
Sbjct: 289 VIEMVLSTDMSGHFQQIKNIRNSLQQ 314



 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
 Frame = +1

Query: 13  YTAFTSRELLTTLQIPARTFLAFAVTLEEHYIR-DNPFHNSLHAADVTQSTNVLLNTPAL 189
           Y  FT  +L+   +IP    + FA  LE  Y +  NP+HN +HAADVTQ+ + ++    +
Sbjct: 147 YELFTRYDLINRFKIPVSCLITFAEALEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGI 206

Query: 190 NAVFTPLEVCAALFAACVHDVD 255
               T LE+ A +FAA +HD +
Sbjct: 207 MHWLTELEILAMVFAAAIHDYE 228



 Score = 40.7 bits (91), Expect = 0.006
 Identities = 16/37 (43%), Positives = 24/37 (64%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHP 783
           +GD+E E G+  SP+CDR +  + +    FID+IV P
Sbjct: 357 QGDKEAELGLPFSPLCDRKSTMVAQSQIGFIDFIVEP 393



 Score = 31.5 bits (68), Expect = 3.6
 Identities = 12/32 (37%), Positives = 19/32 (59%)
 Frame = +2

Query: 557 DRIQVLENLVHCADLSNPTKPLPLYKRWVALL 652
           DR + +  ++H AD+S+P K   L+ RW   L
Sbjct: 319 DRAKTMSLILHAADISHPAKSWKLHYRWTMAL 350


>AB038224-6|BAB20052.1|  552|Homo sapiens calmodulin-dependent
           phosphodiesterase protein.
          Length = 552

 Score = 89.4 bits (212), Expect = 1e-17
 Identities = 37/86 (43%), Positives = 61/86 (70%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G TN F + + S++A++YND SVLENHH++ A++L+Q +  +I +NL K   + LR +
Sbjct: 263 HTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLRNL 322

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           VI+MVLSTDMS H   + +++  +++
Sbjct: 323 VIEMVLSTDMSGHFQQIKNIRNSLQQ 348



 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
 Frame = +1

Query: 13  YTAFTSRELLTTLQIPARTFLAFAVTLEEHYIR-DNPFHNSLHAADVTQSTNVLLNTPAL 189
           Y  FT  +L+   +IP    + FA  LE  Y +  NP+HN +HAADVTQ+ + ++    +
Sbjct: 181 YELFTRYDLINRFKIPVSCLITFAEALEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGI 240

Query: 190 NAVFTPLEVCAALFAACVHDVD 255
               T LE+ A +FAA +HD +
Sbjct: 241 MHWLTELEILAMVFAAAIHDYE 262



 Score = 40.7 bits (91), Expect = 0.006
 Identities = 16/37 (43%), Positives = 24/37 (64%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHP 783
           +GD+E E G+  SP+CDR +  + +    FID+IV P
Sbjct: 391 QGDKEAELGLPFSPLCDRKSTMVAQSQIGFIDFIVEP 427



 Score = 31.5 bits (68), Expect = 3.6
 Identities = 12/32 (37%), Positives = 19/32 (59%)
 Frame = +2

Query: 557 DRIQVLENLVHCADLSNPTKPLPLYKRWVALL 652
           DR + +  ++H AD+S+P K   L+ RW   L
Sbjct: 353 DRAKTMSLILHAADISHPAKSWKLHYRWTMAL 384


>AB038224-5|BAB20050.1|  535|Homo sapiens calmodulin-dependent
           phosphodiesterase protein.
          Length = 535

 Score = 89.4 bits (212), Expect = 1e-17
 Identities = 37/86 (43%), Positives = 61/86 (70%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G TN F + + S++A++YND SVLENHH++ A++L+Q +  +I +NL K   + LR +
Sbjct: 263 HTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLRNL 322

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           VI+MVLSTDMS H   + +++  +++
Sbjct: 323 VIEMVLSTDMSGHFQQIKNIRNSLQQ 348



 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
 Frame = +1

Query: 13  YTAFTSRELLTTLQIPARTFLAFAVTLEEHYIR-DNPFHNSLHAADVTQSTNVLLNTPAL 189
           Y  FT  +L+   +IP    + FA  LE  Y +  NP+HN +HAADVTQ+ + ++    +
Sbjct: 181 YELFTRYDLINRFKIPVSCLITFAEALEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGI 240

Query: 190 NAVFTPLEVCAALFAACVHDVD 255
               T LE+ A +FAA +HD +
Sbjct: 241 MHWLTELEILAMVFAAAIHDYE 262



 Score = 40.7 bits (91), Expect = 0.006
 Identities = 16/37 (43%), Positives = 24/37 (64%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHP 783
           +GD+E E G+  SP+CDR +  + +    FID+IV P
Sbjct: 391 QGDKEAELGLPFSPLCDRKSTMVAQSQIGFIDFIVEP 427



 Score = 31.5 bits (68), Expect = 3.6
 Identities = 12/32 (37%), Positives = 19/32 (59%)
 Frame = +2

Query: 557 DRIQVLENLVHCADLSNPTKPLPLYKRWVALL 652
           DR + +  ++H AD+S+P K   L+ RW   L
Sbjct: 353 DRAKTMSLILHAADISHPAKSWKLHYRWTMAL 384


>AB038224-4|BAB20056.1|  545|Homo sapiens calmodulin-dependent
           phosphodiesterase protein.
          Length = 545

 Score = 89.4 bits (212), Expect = 1e-17
 Identities = 37/86 (43%), Positives = 61/86 (70%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G TN F + + S++A++YND SVLENHH++ A++L+Q +  +I +NL K   + LR +
Sbjct: 263 HTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLRNL 322

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           VI+MVLSTDMS H   + +++  +++
Sbjct: 323 VIEMVLSTDMSGHFQQIKNIRNSLQQ 348



 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
 Frame = +1

Query: 13  YTAFTSRELLTTLQIPARTFLAFAVTLEEHYIR-DNPFHNSLHAADVTQSTNVLLNTPAL 189
           Y  FT  +L+   +IP    + FA  LE  Y +  NP+HN +HAADVTQ+ + ++    +
Sbjct: 181 YELFTRYDLINRFKIPVSCLITFAEALEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGI 240

Query: 190 NAVFTPLEVCAALFAACVHDVD 255
               T LE+ A +FAA +HD +
Sbjct: 241 MHWLTELEILAMVFAAAIHDYE 262



 Score = 40.7 bits (91), Expect = 0.006
 Identities = 16/37 (43%), Positives = 24/37 (64%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHP 783
           +GD+E E G+  SP+CDR +  + +    FID+IV P
Sbjct: 391 QGDKEAELGLPFSPLCDRKSTMVAQSQIGFIDFIVEP 427



 Score = 31.5 bits (68), Expect = 3.6
 Identities = 12/32 (37%), Positives = 19/32 (59%)
 Frame = +2

Query: 557 DRIQVLENLVHCADLSNPTKPLPLYKRWVALL 652
           DR + +  ++H AD+S+P K   L+ RW   L
Sbjct: 353 DRAKTMSLILHAADISHPAKSWKLHYRWTMAL 384


>AB038224-3|BAB20051.1|  536|Homo sapiens calmodulin-dependent
           phosphodiesterase protein.
          Length = 536

 Score = 89.4 bits (212), Expect = 1e-17
 Identities = 37/86 (43%), Positives = 61/86 (70%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G TN F + + S++A++YND SVLENHH++ A++L+Q +  +I +NL K   + LR +
Sbjct: 247 HTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLRNL 306

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           VI+MVLSTDMS H   + +++  +++
Sbjct: 307 VIEMVLSTDMSGHFQQIKNIRNSLQQ 332



 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
 Frame = +1

Query: 13  YTAFTSRELLTTLQIPARTFLAFAVTLEEHYIR-DNPFHNSLHAADVTQSTNVLLNTPAL 189
           Y  FT  +L+   +IP    + FA  LE  Y +  NP+HN +HAADVTQ+ + ++    +
Sbjct: 165 YELFTRYDLINRFKIPVSCLITFAEALEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGI 224

Query: 190 NAVFTPLEVCAALFAACVHDVD 255
               T LE+ A +FAA +HD +
Sbjct: 225 MHWLTELEILAMVFAAAIHDYE 246



 Score = 40.7 bits (91), Expect = 0.006
 Identities = 16/37 (43%), Positives = 24/37 (64%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHP 783
           +GD+E E G+  SP+CDR +  + +    FID+IV P
Sbjct: 375 QGDKEAELGLPFSPLCDRKSTMVAQSQIGFIDFIVEP 411



 Score = 31.5 bits (68), Expect = 3.6
 Identities = 12/32 (37%), Positives = 19/32 (59%)
 Frame = +2

Query: 557 DRIQVLENLVHCADLSNPTKPLPLYKRWVALL 652
           DR + +  ++H AD+S+P K   L+ RW   L
Sbjct: 337 DRAKTMSLILHAADISHPAKSWKLHYRWTMAL 368


>AB038224-2|BAB20049.1|  519|Homo sapiens calmodulin-dependent
           phosphodiesterase protein.
          Length = 519

 Score = 89.4 bits (212), Expect = 1e-17
 Identities = 37/86 (43%), Positives = 61/86 (70%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G TN F + + S++A++YND SVLENHH++ A++L+Q +  +I +NL K   + LR +
Sbjct: 247 HTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLRNL 306

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           VI+MVLSTDMS H   + +++  +++
Sbjct: 307 VIEMVLSTDMSGHFQQIKNIRNSLQQ 332



 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
 Frame = +1

Query: 13  YTAFTSRELLTTLQIPARTFLAFAVTLEEHYIR-DNPFHNSLHAADVTQSTNVLLNTPAL 189
           Y  FT  +L+   +IP    + FA  LE  Y +  NP+HN +HAADVTQ+ + ++    +
Sbjct: 165 YELFTRYDLINRFKIPVSCLITFAEALEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGI 224

Query: 190 NAVFTPLEVCAALFAACVHDVD 255
               T LE+ A +FAA +HD +
Sbjct: 225 MHWLTELEILAMVFAAAIHDYE 246



 Score = 40.7 bits (91), Expect = 0.006
 Identities = 16/37 (43%), Positives = 24/37 (64%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHP 783
           +GD+E E G+  SP+CDR +  + +    FID+IV P
Sbjct: 375 QGDKEAELGLPFSPLCDRKSTMVAQSQIGFIDFIVEP 411



 Score = 31.5 bits (68), Expect = 3.6
 Identities = 12/32 (37%), Positives = 19/32 (59%)
 Frame = +2

Query: 557 DRIQVLENLVHCADLSNPTKPLPLYKRWVALL 652
           DR + +  ++H AD+S+P K   L+ RW   L
Sbjct: 337 DRAKTMSLILHAADISHPAKSWKLHYRWTMAL 368


>AB038224-1|BAB20055.1|  529|Homo sapiens calmodulin-dependent
           phosphodiesterase protein.
          Length = 529

 Score = 89.4 bits (212), Expect = 1e-17
 Identities = 37/86 (43%), Positives = 61/86 (70%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G TN F + + S++A++YND SVLENHH++ A++L+Q +  +I +NL K   + LR +
Sbjct: 247 HTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLRNL 306

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           VI+MVLSTDMS H   + +++  +++
Sbjct: 307 VIEMVLSTDMSGHFQQIKNIRNSLQQ 332



 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
 Frame = +1

Query: 13  YTAFTSRELLTTLQIPARTFLAFAVTLEEHYIR-DNPFHNSLHAADVTQSTNVLLNTPAL 189
           Y  FT  +L+   +IP    + FA  LE  Y +  NP+HN +HAADVTQ+ + ++    +
Sbjct: 165 YELFTRYDLINRFKIPVSCLITFAEALEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGI 224

Query: 190 NAVFTPLEVCAALFAACVHDVD 255
               T LE+ A +FAA +HD +
Sbjct: 225 MHWLTELEILAMVFAAAIHDYE 246



 Score = 40.7 bits (91), Expect = 0.006
 Identities = 16/37 (43%), Positives = 24/37 (64%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHP 783
           +GD+E E G+  SP+CDR +  + +    FID+IV P
Sbjct: 375 QGDKEAELGLPFSPLCDRKSTMVAQSQIGFIDFIVEP 411



 Score = 31.5 bits (68), Expect = 3.6
 Identities = 12/32 (37%), Positives = 19/32 (59%)
 Frame = +2

Query: 557 DRIQVLENLVHCADLSNPTKPLPLYKRWVALL 652
           DR + +  ++H AD+S+P K   L+ RW   L
Sbjct: 337 DRAKTMSLILHAADISHPAKSWKLHYRWTMAL 368


>U40372-1|AAA96961.1|  564|Homo sapiens PDE1C3 protein.
          Length = 564

 Score = 85.0 bits (201), Expect = 3e-16
 Identities = 39/87 (44%), Positives = 60/87 (68%), Gaps = 1/87 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQND-GCDIFVNLHKKQRQTLRK 431
           H G TN F + + S+ A++YND SVLENHHL+ A++LLQ+D   +I +NL K   +  R 
Sbjct: 127 HTGTTNNFHIQTRSDPAILYNDRSVLENHHLSAAYRLLQDDEEMNILINLSKDDWREFRT 186

Query: 432 MVIDMVLSTDMSKHMSLLADLKTMVER 512
           +VI+MV++TDMS H   +  +KT +++
Sbjct: 187 LVIEMVMATDMSCHFQQIKAMKTALQQ 213



 Score = 62.5 bits (145), Expect = 2e-09
 Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
 Frame = +1

Query: 7   VAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRD-NPFHNSLHAADVTQSTNVLLNTP 183
           + Y   T  +L++  +IP    ++F   LE  Y +  NP+HN +HAADVTQ+ + LL   
Sbjct: 43  IFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTVHYLLYKT 102

Query: 184 ALNAVFTPLEVCAALFAACVHDVD 255
            +    T LE+ A +F+A +HD +
Sbjct: 103 GVANWLTELEIFAIIFSAAIHDYE 126



 Score = 41.9 bits (94), Expect = 0.003
 Identities = 17/37 (45%), Positives = 24/37 (64%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHP 783
           +GDRE E G+  SP+CDR +  + +    FID+IV P
Sbjct: 256 QGDREAELGLPFSPLCDRKSTMVAQSQVGFIDFIVEP 292


>U40371-1|AAC50437.1|  634|Homo sapiens 3',5' cyclic nucleotide
           phosphodiesterase protein.
          Length = 634

 Score = 85.0 bits (201), Expect = 3e-16
 Identities = 39/87 (44%), Positives = 60/87 (68%), Gaps = 1/87 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQND-GCDIFVNLHKKQRQTLRK 431
           H G TN F + + S+ A++YND SVLENHHL+ A++LLQ+D   +I +NL K   +  R 
Sbjct: 272 HTGTTNNFHIQTRSDPAILYNDRSVLENHHLSAAYRLLQDDEEMNILINLSKDDWREFRT 331

Query: 432 MVIDMVLSTDMSKHMSLLADLKTMVER 512
           +VI+MV++TDMS H   +  +KT +++
Sbjct: 332 LVIEMVMATDMSCHFQQIKAMKTALQQ 358



 Score = 62.5 bits (145), Expect = 2e-09
 Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
 Frame = +1

Query: 7   VAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRD-NPFHNSLHAADVTQSTNVLLNTP 183
           + Y   T  +L++  +IP    ++F   LE  Y +  NP+HN +HAADVTQ+ + LL   
Sbjct: 188 IFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTVHYLLYKT 247

Query: 184 ALNAVFTPLEVCAALFAACVHDVD 255
            +    T LE+ A +F+A +HD +
Sbjct: 248 GVANWLTELEIFAIIFSAAIHDYE 271



 Score = 41.9 bits (94), Expect = 0.003
 Identities = 17/37 (45%), Positives = 24/37 (64%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHP 783
           +GDRE E G+  SP+CDR +  + +    FID+IV P
Sbjct: 401 QGDREAELGLPFSPLCDRKSTMVAQSQVGFIDFIVEP 437


>BC022525-1|AAH22525.1|  634|Homo sapiens PDE1C protein protein.
          Length = 634

 Score = 85.0 bits (201), Expect = 3e-16
 Identities = 39/87 (44%), Positives = 60/87 (68%), Gaps = 1/87 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQND-GCDIFVNLHKKQRQTLRK 431
           H G TN F + + S+ A++YND SVLENHHL+ A++LLQ+D   +I +NL K   +  R 
Sbjct: 272 HTGTTNNFHIQTRSDPAILYNDRSVLENHHLSAAYRLLQDDEEMNILINLSKDDWREFRT 331

Query: 432 MVIDMVLSTDMSKHMSLLADLKTMVER 512
           +VI+MV++TDMS H   +  +KT +++
Sbjct: 332 LVIEMVMATDMSCHFQQIKAMKTALQQ 358



 Score = 62.5 bits (145), Expect = 2e-09
 Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
 Frame = +1

Query: 7   VAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRD-NPFHNSLHAADVTQSTNVLLNTP 183
           + Y   T  +L++  +IP    ++F   LE  Y +  NP+HN +HAADVTQ+ + LL   
Sbjct: 188 IFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTVHYLLYKT 247

Query: 184 ALNAVFTPLEVCAALFAACVHDVD 255
            +    T LE+ A +F+A +HD +
Sbjct: 248 GVANWLTELEIFAIIFSAAIHDYE 271



 Score = 41.9 bits (94), Expect = 0.003
 Identities = 17/37 (45%), Positives = 24/37 (64%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHP 783
           +GDRE E G+  SP+CDR +  + +    FID+IV P
Sbjct: 401 QGDREAELGLPFSPLCDRKSTMVAQSQVGFIDFIVEP 437


>BC022479-1|AAH22479.1|  634|Homo sapiens PDE1C protein protein.
          Length = 634

 Score = 85.0 bits (201), Expect = 3e-16
 Identities = 39/87 (44%), Positives = 60/87 (68%), Gaps = 1/87 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQND-GCDIFVNLHKKQRQTLRK 431
           H G TN F + + S+ A++YND SVLENHHL+ A++LLQ+D   +I +NL K   +  R 
Sbjct: 272 HTGTTNNFHIQTRSDPAILYNDRSVLENHHLSAAYRLLQDDEEMNILINLSKDDWREFRT 331

Query: 432 MVIDMVLSTDMSKHMSLLADLKTMVER 512
           +VI+MV++TDMS H   +  +KT +++
Sbjct: 332 LVIEMVMATDMSCHFQQIKAMKTALQQ 358



 Score = 62.5 bits (145), Expect = 2e-09
 Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
 Frame = +1

Query: 7   VAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRD-NPFHNSLHAADVTQSTNVLLNTP 183
           + Y   T  +L++  +IP    ++F   LE  Y +  NP+HN +HAADVTQ+ + LL   
Sbjct: 188 IFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTVHYLLYKT 247

Query: 184 ALNAVFTPLEVCAALFAACVHDVD 255
            +    T LE+ A +F+A +HD +
Sbjct: 248 GVANWLTELEIFAIIFSAAIHDYE 271



 Score = 41.9 bits (94), Expect = 0.003
 Identities = 17/37 (45%), Positives = 24/37 (64%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHP 783
           +GDRE E G+  SP+CDR +  + +    FID+IV P
Sbjct: 401 QGDREAELGLPFSPLCDRKSTMVAQSQVGFIDFIVEP 437


>AK091734-1|BAC03734.1|  769|Homo sapiens (EC 3.1.4.17).  protein.
          Length = 769

 Score = 85.0 bits (201), Expect = 3e-16
 Identities = 39/87 (44%), Positives = 60/87 (68%), Gaps = 1/87 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQND-GCDIFVNLHKKQRQTLRK 431
           H G TN F + + S+ A++YND SVLENHHL+ A++LLQ+D   +I +NL K   +  R 
Sbjct: 332 HTGTTNNFHIQTRSDPAILYNDRSVLENHHLSAAYRLLQDDEEMNILINLSKDDWREFRT 391

Query: 432 MVIDMVLSTDMSKHMSLLADLKTMVER 512
           +VI+MV++TDMS H   +  +KT +++
Sbjct: 392 LVIEMVMATDMSCHFQQIKAMKTALQQ 418



 Score = 62.5 bits (145), Expect = 2e-09
 Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
 Frame = +1

Query: 7   VAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRD-NPFHNSLHAADVTQSTNVLLNTP 183
           + Y   T  +L++  +IP    ++F   LE  Y +  NP+HN +HAADVTQ+ + LL   
Sbjct: 248 IFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTVHYLLYKT 307

Query: 184 ALNAVFTPLEVCAALFAACVHDVD 255
            +    T LE+ A +F+A +HD +
Sbjct: 308 GVANWLTELEIFAIIFSAAIHDYE 331



 Score = 41.9 bits (94), Expect = 0.003
 Identities = 17/37 (45%), Positives = 24/37 (64%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHP 783
           +GDRE E G+  SP+CDR +  + +    FID+IV P
Sbjct: 461 QGDREAELGLPFSPLCDRKSTMVAQSQVGFIDFIVEP 497


>AC006377-1|AAS07516.1|  591|Homo sapiens unknown protein.
          Length = 591

 Score = 85.0 bits (201), Expect = 3e-16
 Identities = 39/87 (44%), Positives = 60/87 (68%), Gaps = 1/87 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQND-GCDIFVNLHKKQRQTLRK 431
           H G TN F + + S+ A++YND SVLENHHL+ A++LLQ+D   +I +NL K   +  R 
Sbjct: 229 HTGTTNNFHIQTRSDPAILYNDRSVLENHHLSAAYRLLQDDEEMNILINLSKDDWREFRT 288

Query: 432 MVIDMVLSTDMSKHMSLLADLKTMVER 512
           +VI+MV++TDMS H   +  +KT +++
Sbjct: 289 LVIEMVMATDMSCHFQQIKAMKTALQQ 315



 Score = 62.5 bits (145), Expect = 2e-09
 Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
 Frame = +1

Query: 7   VAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRD-NPFHNSLHAADVTQSTNVLLNTP 183
           + Y   T  +L++  +IP    ++F   LE  Y +  NP+HN +HAADVTQ+ + LL   
Sbjct: 145 IFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTVHYLLYKT 204

Query: 184 ALNAVFTPLEVCAALFAACVHDVD 255
            +    T LE+ A +F+A +HD +
Sbjct: 205 GVANWLTELEIFAIIFSAAIHDYE 228



 Score = 41.9 bits (94), Expect = 0.003
 Identities = 17/37 (45%), Positives = 24/37 (64%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHP 783
           +GDRE E G+  SP+CDR +  + +    FID+IV P
Sbjct: 358 QGDREAELGLPFSPLCDRKSTMVAQSQVGFIDFIVEP 394


>M94539-1|AAA58405.1|  116|Homo sapiens cyclic nucleotide
           phosphodiesterase protein.
          Length = 116

 Score = 84.6 bits (200), Expect = 4e-16
 Identities = 37/71 (52%), Positives = 53/71 (74%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G TN F + + SE A++YND SVLENHH++  F+L+Q+D  +IF+NL K +   LR +
Sbjct: 46  HTGTTNSFHIQTKSECAIVYNDRSVLENHHISSVFRLMQDDEMNIFINLTKDEFVELRAL 105

Query: 435 VIDMVLSTDMS 467
           VI+MVL+TDM+
Sbjct: 106 VIEMVLATDMA 116



 Score = 44.0 bits (99), Expect = 6e-04
 Identities = 18/45 (40%), Positives = 29/45 (64%)
 Frame = +1

Query: 121 FHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVHDVD 255
           +HNS+HAADVTQ+ +  L    +    + +E+ A +FAA +HD +
Sbjct: 1   YHNSMHAADVTQTVHCFLLRTGMVHCLSEIELLAIIFAAAIHDYE 45


>AY266362-1|AAP31234.1|  102|Homo sapiens phosphodiesterase isozyme
           4 protein.
          Length = 102

 Score = 84.2 bits (199), Expect = 5e-16
 Identities = 45/86 (52%), Positives = 52/86 (60%)
 Frame = +2

Query: 509 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLDGRVLPAKAIVN 688
           TKKV  SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W   +            
Sbjct: 4   TKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRER 63

Query: 689 VNMAWISVQCVTDIMLLLEKSQVGLL 766
                IS  C       +EKSQVG +
Sbjct: 64  ERGMEISPMC-DKHTASVEKSQVGFI 88



 Score = 68.1 bits (159), Expect = 3e-11
 Identities = 27/39 (69%), Positives = 32/39 (82%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GDRERE GM+ISPMCD+H A++ K    FIDYIVHPLW
Sbjct: 58  QGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLW 96


>BT007016-1|AAP35662.1|  533|Homo sapiens phosphodiesterase 9A
           protein.
          Length = 533

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/85 (41%), Positives = 56/85 (65%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG  N + +N+ +ELA+ YND S LENHH AVAF++L    C+IF N+     + +R+ 
Sbjct: 296 HPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQG 355

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVE 509
           +I ++L+TDM++H  ++   K  +E
Sbjct: 356 MITLILATDMARHAEIMDSFKEKME 380



 Score = 33.5 bits (73), Expect = 0.89
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +1

Query: 37  LLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEV 216
           L+    I   T   +   + ++Y R+NPFHN  H   V Q    ++   +L   F+  ++
Sbjct: 224 LVRDFSINPVTLRRWLFCVHDNY-RNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDI 282

Query: 217 CAALFAACVHDVD 255
              + AA  HD+D
Sbjct: 283 LILMTAAICHDLD 295


>BC009047-1|AAH09047.1|  533|Homo sapiens phosphodiesterase 9A
           protein.
          Length = 533

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/85 (41%), Positives = 56/85 (65%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG  N + +N+ +ELA+ YND S LENHH AVAF++L    C+IF N+     + +R+ 
Sbjct: 296 HPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQG 355

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVE 509
           +I ++L+TDM++H  ++   K  +E
Sbjct: 356 MITLILATDMARHAEIMDSFKEKME 380



 Score = 33.5 bits (73), Expect = 0.89
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +1

Query: 37  LLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEV 216
           L+    I   T   +   + ++Y R+NPFHN  H   V Q    ++   +L   F+  ++
Sbjct: 224 LVRDFSINPVTLRRWLFCVHDNY-RNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDI 282

Query: 217 CAALFAACVHDVD 255
              + AA  HD+D
Sbjct: 283 LILMTAAICHDLD 295


>AY701187-1|AAV84271.1|  485|Homo sapiens phosphodiesterase PDE9A21
           protein.
          Length = 485

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/85 (41%), Positives = 56/85 (65%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG  N + +N+ +ELA+ YND S LENHH AVAF++L    C+IF N+     + +R+ 
Sbjct: 248 HPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQG 307

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVE 509
           +I ++L+TDM++H  ++   K  +E
Sbjct: 308 MITLILATDMARHAEIMDSFKEKME 332



 Score = 33.5 bits (73), Expect = 0.89
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +1

Query: 37  LLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEV 216
           L+    I   T   +   + ++Y R+NPFHN  H   V Q    ++   +L   F+  ++
Sbjct: 176 LVRDFSINPVTLRRWLFCVHDNY-RNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDI 234

Query: 217 CAALFAACVHDVD 255
              + AA  HD+D
Sbjct: 235 LILMTAAICHDLD 247


>AY242121-1|AAO88210.1|  492|Homo sapiens type 9 cGMP-specific
           phosphodiesterase isoform 5 protein.
          Length = 492

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/85 (41%), Positives = 56/85 (65%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG  N + +N+ +ELA+ YND S LENHH AVAF++L    C+IF N+     + +R+ 
Sbjct: 255 HPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQG 314

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVE 509
           +I ++L+TDM++H  ++   K  +E
Sbjct: 315 MITLILATDMARHAEIMDSFKEKME 339



 Score = 33.5 bits (73), Expect = 0.89
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +1

Query: 37  LLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEV 216
           L+    I   T   +   + ++Y R+NPFHN  H   V Q    ++   +L   F+  ++
Sbjct: 183 LVRDFSINPVTLRRWLFCVHDNY-RNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDI 241

Query: 217 CAALFAACVHDVD 255
              + AA  HD+D
Sbjct: 242 LILMTAAICHDLD 254


>AY196314-1|AAO34700.1|  386|Homo sapiens phosphodiesterase PDE9A20
           protein.
          Length = 386

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/85 (41%), Positives = 56/85 (65%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG  N + +N+ +ELA+ YND S LENHH AVAF++L    C+IF N+     + +R+ 
Sbjct: 149 HPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQG 208

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVE 509
           +I ++L+TDM++H  ++   K  +E
Sbjct: 209 MITLILATDMARHAEIMDSFKEKME 233



 Score = 33.5 bits (73), Expect = 0.89
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +1

Query: 37  LLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEV 216
           L+    I   T   +   + ++Y R+NPFHN  H   V Q    ++   +L   F+  ++
Sbjct: 77  LVRDFSINPVTLRRWLFCVHDNY-RNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDI 135

Query: 217 CAALFAACVHDVD 255
              + AA  HD+D
Sbjct: 136 LILMTAAICHDLD 148


>AY196313-1|AAO34699.1|  386|Homo sapiens phosphodiesterase PDE9A19
           protein.
          Length = 386

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/85 (41%), Positives = 56/85 (65%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG  N + +N+ +ELA+ YND S LENHH AVAF++L    C+IF N+     + +R+ 
Sbjct: 149 HPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQG 208

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVE 509
           +I ++L+TDM++H  ++   K  +E
Sbjct: 209 MITLILATDMARHAEIMDSFKEKME 233



 Score = 33.5 bits (73), Expect = 0.89
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +1

Query: 37  LLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEV 216
           L+    I   T   +   + ++Y R+NPFHN  H   V Q    ++   +L   F+  ++
Sbjct: 77  LVRDFSINPVTLRRWLFCVHDNY-RNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDI 135

Query: 217 CAALFAACVHDVD 255
              + AA  HD+D
Sbjct: 136 LILMTAAICHDLD 148


>AY196312-1|AAO34698.1|  567|Homo sapiens phosphodiesterase PDE9A18
           protein.
          Length = 567

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/85 (41%), Positives = 56/85 (65%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG  N + +N+ +ELA+ YND S LENHH AVAF++L    C+IF N+     + +R+ 
Sbjct: 330 HPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQG 389

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVE 509
           +I ++L+TDM++H  ++   K  +E
Sbjct: 390 MITLILATDMARHAEIMDSFKEKME 414



 Score = 33.5 bits (73), Expect = 0.89
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +1

Query: 37  LLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEV 216
           L+    I   T   +   + ++Y R+NPFHN  H   V Q    ++   +L   F+  ++
Sbjct: 258 LVRDFSINPVTLRRWLFCVHDNY-RNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDI 316

Query: 217 CAALFAACVHDVD 255
              + AA  HD+D
Sbjct: 317 LILMTAAICHDLD 329


>AY196311-1|AAO34697.1|  552|Homo sapiens phosphodiesterase PDE9A17
           protein.
          Length = 552

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/85 (41%), Positives = 56/85 (65%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG  N + +N+ +ELA+ YND S LENHH AVAF++L    C+IF N+     + +R+ 
Sbjct: 315 HPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQG 374

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVE 509
           +I ++L+TDM++H  ++   K  +E
Sbjct: 375 MITLILATDMARHAEIMDSFKEKME 399



 Score = 33.5 bits (73), Expect = 0.89
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +1

Query: 37  LLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEV 216
           L+    I   T   +   + ++Y R+NPFHN  H   V Q    ++   +L   F+  ++
Sbjct: 243 LVRDFSINPVTLRRWLFCVHDNY-RNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDI 301

Query: 217 CAALFAACVHDVD 255
              + AA  HD+D
Sbjct: 302 LILMTAAICHDLD 314


>AY196310-1|AAO34696.1|  526|Homo sapiens phosphodiesterase PDE9A16
           protein.
          Length = 526

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/85 (41%), Positives = 56/85 (65%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG  N + +N+ +ELA+ YND S LENHH AVAF++L    C+IF N+     + +R+ 
Sbjct: 289 HPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQG 348

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVE 509
           +I ++L+TDM++H  ++   K  +E
Sbjct: 349 MITLILATDMARHAEIMDSFKEKME 373



 Score = 33.5 bits (73), Expect = 0.89
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +1

Query: 37  LLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEV 216
           L+    I   T   +   + ++Y R+NPFHN  H   V Q    ++   +L   F+  ++
Sbjct: 217 LVRDFSINPVTLRRWLFCVHDNY-RNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDI 275

Query: 217 CAALFAACVHDVD 255
              + AA  HD+D
Sbjct: 276 LILMTAAICHDLD 288


>AY196309-1|AAO34695.1|  376|Homo sapiens phosphodiesterase PDE9A15
           protein.
          Length = 376

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/85 (41%), Positives = 56/85 (65%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG  N + +N+ +ELA+ YND S LENHH AVAF++L    C+IF N+     + +R+ 
Sbjct: 139 HPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQG 198

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVE 509
           +I ++L+TDM++H  ++   K  +E
Sbjct: 199 MITLILATDMARHAEIMDSFKEKME 223



 Score = 33.5 bits (73), Expect = 0.89
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +1

Query: 37  LLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEV 216
           L+    I   T   +   + ++Y R+NPFHN  H   V Q    ++   +L   F+  ++
Sbjct: 67  LVRDFSINPVTLRRWLFCVHDNY-RNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDI 125

Query: 217 CAALFAACVHDVD 255
              + AA  HD+D
Sbjct: 126 LILMTAAICHDLD 138


>AY196308-1|AAO34694.1|  386|Homo sapiens phosphodiesterase PDE9A14
           protein.
          Length = 386

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/85 (41%), Positives = 56/85 (65%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG  N + +N+ +ELA+ YND S LENHH AVAF++L    C+IF N+     + +R+ 
Sbjct: 149 HPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQG 208

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVE 509
           +I ++L+TDM++H  ++   K  +E
Sbjct: 209 MITLILATDMARHAEIMDSFKEKME 233



 Score = 33.5 bits (73), Expect = 0.89
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +1

Query: 37  LLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEV 216
           L+    I   T   +   + ++Y R+NPFHN  H   V Q    ++   +L   F+  ++
Sbjct: 77  LVRDFSINPVTLRRWLFCVHDNY-RNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDI 135

Query: 217 CAALFAACVHDVD 255
              + AA  HD+D
Sbjct: 136 LILMTAAICHDLD 148


>AY196307-1|AAO34693.1|  491|Homo sapiens phosphodiesterase PDE9A13
           protein.
          Length = 491

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/85 (41%), Positives = 56/85 (65%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG  N + +N+ +ELA+ YND S LENHH AVAF++L    C+IF N+     + +R+ 
Sbjct: 254 HPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQG 313

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVE 509
           +I ++L+TDM++H  ++   K  +E
Sbjct: 314 MITLILATDMARHAEIMDSFKEKME 338



 Score = 33.5 bits (73), Expect = 0.89
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +1

Query: 37  LLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEV 216
           L+    I   T   +   + ++Y R+NPFHN  H   V Q    ++   +L   F+  ++
Sbjct: 182 LVRDFSINPVTLRRWLFCVHDNY-RNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDI 240

Query: 217 CAALFAACVHDVD 255
              + AA  HD+D
Sbjct: 241 LILMTAAICHDLD 253


>AY196306-1|AAO34692.1|  459|Homo sapiens phosphodiesterase PDE9A12
           protein.
          Length = 459

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/85 (41%), Positives = 56/85 (65%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG  N + +N+ +ELA+ YND S LENHH AVAF++L    C+IF N+     + +R+ 
Sbjct: 222 HPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQG 281

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVE 509
           +I ++L+TDM++H  ++   K  +E
Sbjct: 282 MITLILATDMARHAEIMDSFKEKME 306



 Score = 33.5 bits (73), Expect = 0.89
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +1

Query: 37  LLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEV 216
           L+    I   T   +   + ++Y R+NPFHN  H   V Q    ++   +L   F+  ++
Sbjct: 150 LVRDFSINPVTLRRWLFCVHDNY-RNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDI 208

Query: 217 CAALFAACVHDVD 255
              + AA  HD+D
Sbjct: 209 LILMTAAICHDLD 221


>AY196305-1|AAO34691.1|  376|Homo sapiens phosphodiesterase PDE9A11
           protein.
          Length = 376

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/85 (41%), Positives = 56/85 (65%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG  N + +N+ +ELA+ YND S LENHH AVAF++L    C+IF N+     + +R+ 
Sbjct: 139 HPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQG 198

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVE 509
           +I ++L+TDM++H  ++   K  +E
Sbjct: 199 MITLILATDMARHAEIMDSFKEKME 223



 Score = 33.5 bits (73), Expect = 0.89
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +1

Query: 37  LLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEV 216
           L+    I   T   +   + ++Y R+NPFHN  H   V Q    ++   +L   F+  ++
Sbjct: 67  LVRDFSINPVTLRRWLFCVHDNY-RNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDI 125

Query: 217 CAALFAACVHDVD 255
              + AA  HD+D
Sbjct: 126 LILMTAAICHDLD 138


>AY196304-1|AAO34690.1|  433|Homo sapiens phosphodiesterase PDE9A10
           protein.
          Length = 433

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/85 (41%), Positives = 56/85 (65%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG  N + +N+ +ELA+ YND S LENHH AVAF++L    C+IF N+     + +R+ 
Sbjct: 196 HPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQG 255

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVE 509
           +I ++L+TDM++H  ++   K  +E
Sbjct: 256 MITLILATDMARHAEIMDSFKEKME 280



 Score = 33.5 bits (73), Expect = 0.89
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +1

Query: 37  LLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEV 216
           L+    I   T   +   + ++Y R+NPFHN  H   V Q    ++   +L   F+  ++
Sbjct: 124 LVRDFSINPVTLRRWLFCVHDNY-RNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDI 182

Query: 217 CAALFAACVHDVD 255
              + AA  HD+D
Sbjct: 183 LILMTAAICHDLD 195


>AY196303-1|AAO34689.1|  507|Homo sapiens phosphodiesterase PDE9A9
           protein.
          Length = 507

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/85 (41%), Positives = 56/85 (65%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG  N + +N+ +ELA+ YND S LENHH AVAF++L    C+IF N+     + +R+ 
Sbjct: 270 HPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQG 329

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVE 509
           +I ++L+TDM++H  ++   K  +E
Sbjct: 330 MITLILATDMARHAEIMDSFKEKME 354



 Score = 33.5 bits (73), Expect = 0.89
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +1

Query: 37  LLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEV 216
           L+    I   T   +   + ++Y R+NPFHN  H   V Q    ++   +L   F+  ++
Sbjct: 198 LVRDFSINPVTLRRWLFCVHDNY-RNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDI 256

Query: 217 CAALFAACVHDVD 255
              + AA  HD+D
Sbjct: 257 LILMTAAICHDLD 269


>AY196302-1|AAO34688.1|  386|Homo sapiens phosphodiesterase PDE9A8
           protein.
          Length = 386

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/85 (41%), Positives = 56/85 (65%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG  N + +N+ +ELA+ YND S LENHH AVAF++L    C+IF N+     + +R+ 
Sbjct: 149 HPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQG 208

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVE 509
           +I ++L+TDM++H  ++   K  +E
Sbjct: 209 MITLILATDMARHAEIMDSFKEKME 233



 Score = 33.5 bits (73), Expect = 0.89
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +1

Query: 37  LLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEV 216
           L+    I   T   +   + ++Y R+NPFHN  H   V Q    ++   +L   F+  ++
Sbjct: 77  LVRDFSINPVTLRRWLFCVHDNY-RNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDI 135

Query: 217 CAALFAACVHDVD 255
              + AA  HD+D
Sbjct: 136 LILMTAAICHDLD 148


>AY196301-1|AAO34687.1|  386|Homo sapiens phosphodiesterase PDE9A7
           protein.
          Length = 386

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/85 (41%), Positives = 56/85 (65%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG  N + +N+ +ELA+ YND S LENHH AVAF++L    C+IF N+     + +R+ 
Sbjct: 149 HPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQG 208

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVE 509
           +I ++L+TDM++H  ++   K  +E
Sbjct: 209 MITLILATDMARHAEIMDSFKEKME 233



 Score = 33.5 bits (73), Expect = 0.89
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +1

Query: 37  LLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEV 216
           L+    I   T   +   + ++Y R+NPFHN  H   V Q    ++   +L   F+  ++
Sbjct: 77  LVRDFSINPVTLRRWLFCVHDNY-RNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDI 135

Query: 217 CAALFAACVHDVD 255
              + AA  HD+D
Sbjct: 136 LILMTAAICHDLD 148


>AY196300-1|AAO34686.1|  492|Homo sapiens phosphodiesterase PDE9A6
           protein.
          Length = 492

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/85 (41%), Positives = 56/85 (65%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG  N + +N+ +ELA+ YND S LENHH AVAF++L    C+IF N+     + +R+ 
Sbjct: 255 HPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQG 314

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVE 509
           +I ++L+TDM++H  ++   K  +E
Sbjct: 315 MITLILATDMARHAEIMDSFKEKME 339



 Score = 33.5 bits (73), Expect = 0.89
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +1

Query: 37  LLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEV 216
           L+    I   T   +   + ++Y R+NPFHN  H   V Q    ++   +L   F+  ++
Sbjct: 183 LVRDFSINPVTLRRWLFCVHDNY-RNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDI 241

Query: 217 CAALFAACVHDVD 255
              + AA  HD+D
Sbjct: 242 LILMTAAICHDLD 254


>AY196299-1|AAO34685.1|  540|Homo sapiens phosphodiesterase PDE9A5
           protein.
          Length = 540

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/85 (41%), Positives = 56/85 (65%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG  N + +N+ +ELA+ YND S LENHH AVAF++L    C+IF N+     + +R+ 
Sbjct: 303 HPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQG 362

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVE 509
           +I ++L+TDM++H  ++   K  +E
Sbjct: 363 MITLILATDMARHAEIMDSFKEKME 387



 Score = 33.5 bits (73), Expect = 0.89
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +1

Query: 37  LLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEV 216
           L+    I   T   +   + ++Y R+NPFHN  H   V Q    ++   +L   F+  ++
Sbjct: 231 LVRDFSINPVTLRRWLFCVHDNY-RNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDI 289

Query: 217 CAALFAACVHDVD 255
              + AA  HD+D
Sbjct: 290 LILMTAAICHDLD 302


>AP001747-1|BAA95552.1|  593|Homo sapiens CGMP-specific 3',5'-cyclic
           phosphodiesterase type 9, EC 3.1.4.17. protein.
          Length = 593

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/85 (41%), Positives = 56/85 (65%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG  N + +N+ +ELA+ YND S LENHH AVAF++L    C+IF N+     + +R+ 
Sbjct: 356 HPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQG 415

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVE 509
           +I ++L+TDM++H  ++   K  +E
Sbjct: 416 MITLILATDMARHAEIMDSFKEKME 440



 Score = 33.5 bits (73), Expect = 0.89
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +1

Query: 37  LLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEV 216
           L+    I   T   +   + ++Y R+NPFHN  H   V Q    ++   +L   F+  ++
Sbjct: 284 LVRDFSINPVTLRRWLFCVHDNY-RNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDI 342

Query: 217 CAALFAACVHDVD 255
              + AA  HD+D
Sbjct: 343 LILMTAAICHDLD 355


>AF067226-1|AAC26726.1|  465|Homo sapiens cGMP phosphodiesterase A4
           protein.
          Length = 465

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/85 (41%), Positives = 56/85 (65%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG  N + +N+ +ELA+ YND S LENHH AVAF++L    C+IF N+     + +R+ 
Sbjct: 228 HPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQG 287

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVE 509
           +I ++L+TDM++H  ++   K  +E
Sbjct: 288 MITLILATDMARHAEIMDSFKEKME 312



 Score = 33.5 bits (73), Expect = 0.89
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +1

Query: 37  LLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEV 216
           L+    I   T   +   + ++Y R+NPFHN  H   V Q    ++   +L   F+  ++
Sbjct: 156 LVRDFSINPVTLRRWLFCVHDNY-RNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDI 214

Query: 217 CAALFAACVHDVD 255
              + AA  HD+D
Sbjct: 215 LILMTAAICHDLD 227


>AF067225-1|AAC26725.1|  466|Homo sapiens cGMP phosphodiesterase A3
           protein.
          Length = 466

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/85 (41%), Positives = 56/85 (65%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG  N + +N+ +ELA+ YND S LENHH AVAF++L    C+IF N+     + +R+ 
Sbjct: 229 HPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQG 288

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVE 509
           +I ++L+TDM++H  ++   K  +E
Sbjct: 289 MITLILATDMARHAEIMDSFKEKME 313



 Score = 33.5 bits (73), Expect = 0.89
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +1

Query: 37  LLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEV 216
           L+    I   T   +   + ++Y R+NPFHN  H   V Q    ++   +L   F+  ++
Sbjct: 157 LVRDFSINPVTLRRWLFCVHDNY-RNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDI 215

Query: 217 CAALFAACVHDVD 255
              + AA  HD+D
Sbjct: 216 LILMTAAICHDLD 228


>AF067224-1|AAC26724.1|  533|Homo sapiens cGMP phosphodiesterase A2
           protein.
          Length = 533

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/85 (41%), Positives = 56/85 (65%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG  N + +N+ +ELA+ YND S LENHH AVAF++L    C+IF N+     + +R+ 
Sbjct: 296 HPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQG 355

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVE 509
           +I ++L+TDM++H  ++   K  +E
Sbjct: 356 MITLILATDMARHAEIMDSFKEKME 380



 Score = 33.5 bits (73), Expect = 0.89
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +1

Query: 37  LLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEV 216
           L+    I   T   +   + ++Y R+NPFHN  H   V Q    ++   +L   F+  ++
Sbjct: 224 LVRDFSINPVTLRRWLFCVHDNY-RNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDI 282

Query: 217 CAALFAACVHDVD 255
              + AA  HD+D
Sbjct: 283 LILMTAAICHDLD 295


>AF067223-1|AAC26723.1|  593|Homo sapiens cGMP phosphodiesterase A1
           protein.
          Length = 593

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/85 (41%), Positives = 56/85 (65%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG  N + +N+ +ELA+ YND S LENHH AVAF++L    C+IF N+     + +R+ 
Sbjct: 356 HPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQG 415

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVE 509
           +I ++L+TDM++H  ++   K  +E
Sbjct: 416 MITLILATDMARHAEIMDSFKEKME 440



 Score = 33.5 bits (73), Expect = 0.89
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +1

Query: 37  LLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEV 216
           L+    I   T   +   + ++Y R+NPFHN  H   V Q    ++   +L   F+  ++
Sbjct: 284 LVRDFSINPVTLRRWLFCVHDNY-RNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDI 342

Query: 217 CAALFAACVHDVD 255
              + AA  HD+D
Sbjct: 343 LILMTAAICHDLD 355


>AF048837-1|AAC39778.1|  593|Homo sapiens cGMP-specific
           phosphodiesterase protein.
          Length = 593

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/85 (41%), Positives = 56/85 (65%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG  N + +N+ +ELA+ YND S LENHH AVAF++L    C+IF N+     + +R+ 
Sbjct: 356 HPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQG 415

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVE 509
           +I ++L+TDM++H  ++   K  +E
Sbjct: 416 MITLILATDMARHAEIMDSFKEKME 440



 Score = 33.5 bits (73), Expect = 0.89
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +1

Query: 37  LLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEV 216
           L+    I   T   +   + ++Y R+NPFHN  H   V Q    ++   +L   F+  ++
Sbjct: 284 LVRDFSINPVTLRRWLFCVHDNY-RNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDI 342

Query: 217 CAALFAACVHDVD 255
              + AA  HD+D
Sbjct: 343 LILMTAAICHDLD 355


>AB017602-1|BAA88847.1|  593|Homo sapiens cGMP phosphodiesterase
           protein.
          Length = 593

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/85 (41%), Positives = 56/85 (65%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG  N + +N+ +ELA+ YND S LENHH AVAF++L    C+IF N+     + +R+ 
Sbjct: 356 HPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQG 415

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVE 509
           +I ++L+TDM++H  ++   K  +E
Sbjct: 416 MITLILATDMARHAEIMDSFKEKME 440



 Score = 33.5 bits (73), Expect = 0.89
 Identities = 20/73 (27%), Positives = 34/73 (46%)
 Frame = +1

Query: 37  LLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEV 216
           L+    I   T   +   + ++Y R+NPFHN  H   V Q    ++   +L   F+  ++
Sbjct: 284 LVRDFSINPVTLRRWLFCVHDNY-RNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDI 342

Query: 217 CAALFAACVHDVD 255
              + AA  HD+D
Sbjct: 343 LILMTAAICHDLD 355


>U67733-1|AAC51320.1|  941|Homo sapiens PDE2A3 protein.
          Length = 941

 Score = 72.5 bits (170), Expect = 2e-12
 Identities = 34/86 (39%), Positives = 52/86 (60%), Gaps = 1/86 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDE-SVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRK 431
           H G  N F V S S LA +Y+ E SV+E HH A A  +L   GC+IF +  +K  Q +  
Sbjct: 700 HRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLD 759

Query: 432 MVIDMVLSTDMSKHMSLLADLKTMVE 509
           ++ D++L+TD++ H+ +  DL+ M E
Sbjct: 760 LMRDIILATDLAHHLRIFKDLQKMAE 785



 Score = 38.3 bits (85), Expect = 0.031
 Identities = 20/76 (26%), Positives = 35/76 (46%)
 Frame = +1

Query: 40  LTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVC 219
           +   +I   T   F + +++ Y RD P+HN +HA  V+    +L     L      +E+ 
Sbjct: 629 INNYKIDCPTLARFCLMVKKGY-RDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIF 687

Query: 220 AALFAACVHDVDTRAS 267
           A   +   HD+D R +
Sbjct: 688 ALFISCMCHDLDHRGT 703


>BC040974-1|AAH40974.1|  941|Homo sapiens phosphodiesterase 2A,
           cGMP-stimulated protein.
          Length = 941

 Score = 72.5 bits (170), Expect = 2e-12
 Identities = 34/86 (39%), Positives = 52/86 (60%), Gaps = 1/86 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDE-SVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRK 431
           H G  N F V S S LA +Y+ E SV+E HH A A  +L   GC+IF +  +K  Q +  
Sbjct: 700 HRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLD 759

Query: 432 MVIDMVLSTDMSKHMSLLADLKTMVE 509
           ++ D++L+TD++ H+ +  DL+ M E
Sbjct: 760 LMRDIILATDLAHHLRIFKDLQKMAE 785



 Score = 38.3 bits (85), Expect = 0.031
 Identities = 20/76 (26%), Positives = 35/76 (46%)
 Frame = +1

Query: 40  LTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVC 219
           +   +I   T   F + +++ Y RD P+HN +HA  V+    +L     L      +E+ 
Sbjct: 629 INNYKIDCPTLARFCLMVKKGY-RDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIF 687

Query: 220 AALFAACVHDVDTRAS 267
           A   +   HD+D R +
Sbjct: 688 ALFISCMCHDLDHRGT 703


>AY495087-1|AAS75513.1|  932|Homo sapiens cGMP-stimulated
           phosphodiesterase 4 protein.
          Length = 932

 Score = 72.5 bits (170), Expect = 2e-12
 Identities = 34/86 (39%), Positives = 52/86 (60%), Gaps = 1/86 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDE-SVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRK 431
           H G  N F V S S LA +Y+ E SV+E HH A A  +L   GC+IF +  +K  Q +  
Sbjct: 691 HRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLD 750

Query: 432 MVIDMVLSTDMSKHMSLLADLKTMVE 509
           ++ D++L+TD++ H+ +  DL+ M E
Sbjct: 751 LMRDIILATDLAHHLRIFKDLQKMAE 776



 Score = 36.7 bits (81), Expect = 0.095
 Identities = 19/76 (25%), Positives = 34/76 (44%)
 Frame = +1

Query: 40  LTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVC 219
           +   +I   T   F + +++ Y RD P+HN +HA   +    +L     L      +E+ 
Sbjct: 620 INNYKIDCPTLARFCLMVKKGY-RDPPYHNWMHAFSASHFCYLLYKNLELTNYLEDIEIF 678

Query: 220 AALFAACVHDVDTRAS 267
           A   +   HD+D R +
Sbjct: 679 ALFISCMCHDLDHRGT 694


>AK131525-1|BAD18664.1|  685|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16750 fis, clone ADRGL2011190, highly  similar
           to cGMP-dependent 3',5'-cyclic phosphodiesterase (EC
           3.1.4.17). ).
          Length = 685

 Score = 72.5 bits (170), Expect = 2e-12
 Identities = 34/86 (39%), Positives = 52/86 (60%), Gaps = 1/86 (1%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDE-SVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRK 431
           H G  N F V S S LA +Y+ E SV+E HH A A  +L   GC+IF +  +K  Q +  
Sbjct: 444 HRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLD 503

Query: 432 MVIDMVLSTDMSKHMSLLADLKTMVE 509
           ++ D++L+TD++ H+ +  DL+ M E
Sbjct: 504 LMRDIILATDLAHHLRIFKDLQKMAE 529



 Score = 38.3 bits (85), Expect = 0.031
 Identities = 20/76 (26%), Positives = 35/76 (46%)
 Frame = +1

Query: 40  LTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVC 219
           +   +I   T   F + +++ Y RD P+HN +HA  V+    +L     L      +E+ 
Sbjct: 373 INNYKIDCPTLARFCLMVKKGY-RDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIF 431

Query: 220 AALFAACVHDVDTRAS 267
           A   +   HD+D R +
Sbjct: 432 ALFISCMCHDLDHRGT 447


>U36798-1|AAB18673.1| 1141|Homo sapiens platelet cGI-PDE protein.
          Length = 1141

 Score = 71.3 bits (167), Expect = 4e-12
 Identities = 34/79 (43%), Positives = 50/79 (63%), Gaps = 1/79 (1%)
 Frame = +3

Query: 255  HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKL-LQNDGCDIFVNLHKKQRQTLRK 431
            HPG TN FLV +S+  A++YND SVLENHH A A+ L +     +  +NL   + +  R 
Sbjct: 840  HPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLINLDHVEFKHFRF 899

Query: 432  MVIDMVLSTDMSKHMSLLA 488
            +VI+ +L+TD+ KH   +A
Sbjct: 900  LVIEAILATDLKKHFDFVA 918



 Score = 41.5 bits (93), Expect = 0.003
 Identities = 22/59 (37%), Positives = 29/59 (49%)
 Frame = +1

Query: 7   VAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTP 183
           V+Y  F    L    +IP R F+ +   LE  Y RD P+HN +HA DV  +   L   P
Sbjct: 714 VSYRLFEDMGLFEAFKIPIREFMNYFHALEIGY-RDIPYHNRIHATDVLHAVWYLTTQP 771



 Score = 33.1 bits (72), Expect = 1.2
 Identities = 15/38 (39%), Positives = 20/38 (52%)
 Frame = +1

Query: 673  KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPL 786
            +GD E   G+ ISP  DR    +  +   FI +IV PL
Sbjct: 975  QGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPL 1012


>M91667-1|AAA35912.2| 1141|Homo sapiens cGMP-inhibited cAMP
            phosphodiesterase protein.
          Length = 1141

 Score = 71.3 bits (167), Expect = 4e-12
 Identities = 34/79 (43%), Positives = 50/79 (63%), Gaps = 1/79 (1%)
 Frame = +3

Query: 255  HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKL-LQNDGCDIFVNLHKKQRQTLRK 431
            HPG TN FLV +S+  A++YND SVLENHH A A+ L +     +  +NL   + +  R 
Sbjct: 840  HPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLINLDHVEFKHFRF 899

Query: 432  MVIDMVLSTDMSKHMSLLA 488
            +VI+ +L+TD+ KH   +A
Sbjct: 900  LVIEAILATDLKKHFDFVA 918



 Score = 41.5 bits (93), Expect = 0.003
 Identities = 22/59 (37%), Positives = 29/59 (49%)
 Frame = +1

Query: 7   VAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTP 183
           V+Y  F    L    +IP R F+ +   LE  Y RD P+HN +HA DV  +   L   P
Sbjct: 714 VSYRLFEDMGLFEAFKIPIREFMNYFHALEIGY-RDIPYHNRIHATDVLHAVWYLTTQP 771



 Score = 33.1 bits (72), Expect = 1.2
 Identities = 15/38 (39%), Positives = 20/38 (52%)
 Frame = +1

Query: 673  KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPL 786
            +GD E   G+ ISP  DR    +  +   FI +IV PL
Sbjct: 975  QGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPL 1012


>BC117371-1|AAI17372.1| 1141|Homo sapiens phosphodiesterase 3A,
            cGMP-inhibited protein.
          Length = 1141

 Score = 71.3 bits (167), Expect = 4e-12
 Identities = 34/79 (43%), Positives = 50/79 (63%), Gaps = 1/79 (1%)
 Frame = +3

Query: 255  HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKL-LQNDGCDIFVNLHKKQRQTLRK 431
            HPG TN FLV +S+  A++YND SVLENHH A A+ L +     +  +NL   + +  R 
Sbjct: 840  HPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLINLDHVEFKHFRF 899

Query: 432  MVIDMVLSTDMSKHMSLLA 488
            +VI+ +L+TD+ KH   +A
Sbjct: 900  LVIEAILATDLKKHFDFVA 918



 Score = 41.5 bits (93), Expect = 0.003
 Identities = 22/59 (37%), Positives = 29/59 (49%)
 Frame = +1

Query: 7   VAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTP 183
           V+Y  F    L    +IP R F+ +   LE  Y RD P+HN +HA DV  +   L   P
Sbjct: 714 VSYRLFEDMGLFEAFKIPIREFMNYFHALEIGY-RDIPYHNRIHATDVLHAVWYLTTQP 771



 Score = 33.1 bits (72), Expect = 1.2
 Identities = 15/38 (39%), Positives = 20/38 (52%)
 Frame = +1

Query: 673  KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPL 786
            +GD E   G+ ISP  DR    +  +   FI +IV PL
Sbjct: 975  QGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPL 1012


>BC117369-1|AAI17370.1| 1141|Homo sapiens phosphodiesterase 3A,
            cGMP-inhibited protein.
          Length = 1141

 Score = 71.3 bits (167), Expect = 4e-12
 Identities = 34/79 (43%), Positives = 50/79 (63%), Gaps = 1/79 (1%)
 Frame = +3

Query: 255  HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKL-LQNDGCDIFVNLHKKQRQTLRK 431
            HPG TN FLV +S+  A++YND SVLENHH A A+ L +     +  +NL   + +  R 
Sbjct: 840  HPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLINLDHVEFKHFRF 899

Query: 432  MVIDMVLSTDMSKHMSLLA 488
            +VI+ +L+TD+ KH   +A
Sbjct: 900  LVIEAILATDLKKHFDFVA 918



 Score = 41.5 bits (93), Expect = 0.003
 Identities = 22/59 (37%), Positives = 29/59 (49%)
 Frame = +1

Query: 7   VAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTP 183
           V+Y  F    L    +IP R F+ +   LE  Y RD P+HN +HA DV  +   L   P
Sbjct: 714 VSYRLFEDMGLFEAFKIPIREFMNYFHALEIGY-RDIPYHNRIHATDVLHAVWYLTTQP 771



 Score = 33.1 bits (72), Expect = 1.2
 Identities = 15/38 (39%), Positives = 20/38 (52%)
 Frame = +1

Query: 673  KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPL 786
            +GD E   G+ ISP  DR    +  +   FI +IV PL
Sbjct: 975  QGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPL 1012


>AJ005036-1|CAA06304.1| 1141|Homo sapiens phosphodiesterase 3A
            protein.
          Length = 1141

 Score = 71.3 bits (167), Expect = 4e-12
 Identities = 34/79 (43%), Positives = 50/79 (63%), Gaps = 1/79 (1%)
 Frame = +3

Query: 255  HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKL-LQNDGCDIFVNLHKKQRQTLRK 431
            HPG TN FLV +S+  A++YND SVLENHH A A+ L +     +  +NL   + +  R 
Sbjct: 840  HPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLINLDHVEFKHFRF 899

Query: 432  MVIDMVLSTDMSKHMSLLA 488
            +VI+ +L+TD+ KH   +A
Sbjct: 900  LVIEAILATDLKKHFDFVA 918



 Score = 41.5 bits (93), Expect = 0.003
 Identities = 22/59 (37%), Positives = 29/59 (49%)
 Frame = +1

Query: 7   VAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTP 183
           V+Y  F    L    +IP R F+ +   LE  Y RD P+HN +HA DV  +   L   P
Sbjct: 714 VSYRLFEDMGLFEAFKIPIREFMNYFHALEIGY-RDIPYHNRIHATDVLHAVWYLTTQP 771



 Score = 33.1 bits (72), Expect = 1.2
 Identities = 15/38 (39%), Positives = 20/38 (52%)
 Frame = +1

Query: 673  KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPL 786
            +GD E   G+ ISP  DR    +  +   FI +IV PL
Sbjct: 975  QGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPL 1012


>X95520-1|CAA64774.1| 1112|Homo sapiens cyclic nucleotide
            phosphodiesterase protein.
          Length = 1112

 Score = 69.7 bits (163), Expect = 1e-11
 Identities = 34/80 (42%), Positives = 51/80 (63%), Gaps = 1/80 (1%)
 Frame = +3

Query: 255  HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKL-LQNDGCDIFVNLHKKQRQTLRK 431
            HPG TN FLV +++  A++YND SVLENHH A A+ L L     +  ++L   + +  R 
Sbjct: 825  HPGRTNAFLVATNAPQAVLYNDRSVLENHHAASAWNLYLSRPEYNFLLHLDHVEFKRFRF 884

Query: 432  MVIDMVLSTDMSKHMSLLAD 491
            +VI+ +L+TD+ KH   LA+
Sbjct: 885  LVIEAILATDLKKHFDFLAE 904



 Score = 44.4 bits (100), Expect = 5e-04
 Identities = 23/59 (38%), Positives = 30/59 (50%)
 Frame = +1

Query: 7   VAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTP 183
           V YT F    LL   +IP + F+ +   LE  Y RD P+HN +HA DV  +   L   P
Sbjct: 699 VMYTLFQDTGLLEIFKIPTQQFMNYFRALENGY-RDIPYHNRIHATDVLHAVWYLTTRP 756



 Score = 35.9 bits (79), Expect = 0.17
 Identities = 16/38 (42%), Positives = 22/38 (57%)
 Frame = +1

Query: 673  KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPL 786
            +GD E   G+ ISP  DR +  + K+   FI +IV PL
Sbjct: 962  QGDEEANLGLPISPFMDRSSPQLAKLQESFITHIVGPL 999


>U38178-1|AAC50724.1| 1112|Homo sapiens cyclic nucleotide
            phophodiesterase protein.
          Length = 1112

 Score = 69.7 bits (163), Expect = 1e-11
 Identities = 34/80 (42%), Positives = 51/80 (63%), Gaps = 1/80 (1%)
 Frame = +3

Query: 255  HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKL-LQNDGCDIFVNLHKKQRQTLRK 431
            HPG TN FLV +++  A++YND SVLENHH A A+ L L     +  ++L   + +  R 
Sbjct: 825  HPGRTNAFLVATNAPQAVLYNDRSVLENHHAASAWNLYLSRPEYNFLLHLDHVEFKRFRF 884

Query: 432  MVIDMVLSTDMSKHMSLLAD 491
            +VI+ +L+TD+ KH   LA+
Sbjct: 885  LVIEAILATDLKKHFDFLAE 904



 Score = 44.4 bits (100), Expect = 5e-04
 Identities = 23/59 (38%), Positives = 30/59 (50%)
 Frame = +1

Query: 7   VAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTP 183
           V YT F    LL   +IP + F+ +   LE  Y RD P+HN +HA DV  +   L   P
Sbjct: 699 VMYTLFQDTGLLEIFKIPTQQFMNYFRALENGY-RDIPYHNRIHATDVLHAVWYLTTRP 756



 Score = 35.9 bits (79), Expect = 0.17
 Identities = 16/38 (42%), Positives = 22/38 (57%)
 Frame = +1

Query: 673  KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPL 786
            +GD E   G+ ISP  DR +  + K+   FI +IV PL
Sbjct: 962  QGDEEANLGLPISPFMDRSSPQLAKLQESFITHIVGPL 999


>D50640-1|BAA09306.1| 1112|Homo sapiens phosphodiesterase 3B protein.
          Length = 1112

 Score = 69.7 bits (163), Expect = 1e-11
 Identities = 34/80 (42%), Positives = 51/80 (63%), Gaps = 1/80 (1%)
 Frame = +3

Query: 255  HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKL-LQNDGCDIFVNLHKKQRQTLRK 431
            HPG TN FLV +++  A++YND SVLENHH A A+ L L     +  ++L   + +  R 
Sbjct: 825  HPGRTNAFLVATNAPQAVLYNDRSVLENHHAASAWNLYLSRPEYNFLLHLDHVEFKRFRF 884

Query: 432  MVIDMVLSTDMSKHMSLLAD 491
            +VI+ +L+TD+ KH   LA+
Sbjct: 885  LVIEAILATDLKKHFDFLAE 904



 Score = 44.4 bits (100), Expect = 5e-04
 Identities = 23/59 (38%), Positives = 30/59 (50%)
 Frame = +1

Query: 7   VAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTP 183
           V YT F    LL   +IP + F+ +   LE  Y RD P+HN +HA DV  +   L   P
Sbjct: 699 VMYTLFQDTGLLEIFKIPTQQFMNYFRALENGY-RDIPYHNRIHATDVLHAVWYLTTRP 756



 Score = 35.9 bits (79), Expect = 0.17
 Identities = 16/38 (42%), Positives = 22/38 (57%)
 Frame = +1

Query: 673  KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPL 786
            +GD E   G+ ISP  DR +  + K+   FI +IV PL
Sbjct: 962  QGDEEANLGLPISPFMDRSSPQLAKLQESFITHIVGPL 999


>BC150307-1|AAI50308.1| 1112|Homo sapiens phosphodiesterase 3B,
            cGMP-inhibited protein.
          Length = 1112

 Score = 69.7 bits (163), Expect = 1e-11
 Identities = 34/80 (42%), Positives = 51/80 (63%), Gaps = 1/80 (1%)
 Frame = +3

Query: 255  HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKL-LQNDGCDIFVNLHKKQRQTLRK 431
            HPG TN FLV +++  A++YND SVLENHH A A+ L L     +  ++L   + +  R 
Sbjct: 825  HPGRTNAFLVATNAPQAVLYNDRSVLENHHAASAWNLYLSRPEYNFLLHLDHVEFKRFRF 884

Query: 432  MVIDMVLSTDMSKHMSLLAD 491
            +VI+ +L+TD+ KH   LA+
Sbjct: 885  LVIEAILATDLKKHFDFLAE 904



 Score = 44.4 bits (100), Expect = 5e-04
 Identities = 23/59 (38%), Positives = 30/59 (50%)
 Frame = +1

Query: 7   VAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTP 183
           V YT F    LL   +IP + F+ +   LE  Y RD P+HN +HA DV  +   L   P
Sbjct: 699 VMYTLFQDTGLLEIFKIPTQQFMNYFRALENGY-RDIPYHNRIHATDVLHAVWYLTTRP 756



 Score = 35.9 bits (79), Expect = 0.17
 Identities = 16/38 (42%), Positives = 22/38 (57%)
 Frame = +1

Query: 673  KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPL 786
            +GD E   G+ ISP  DR +  + K+   FI +IV PL
Sbjct: 962  QGDEEANLGLPISPFMDRSSPQLAKLQESFITHIVGPL 999


>AY459346-1|AAR24292.1| 1112|Homo sapiens cGMP-inhibited cAMP
            phophodiesterase protein.
          Length = 1112

 Score = 69.7 bits (163), Expect = 1e-11
 Identities = 34/80 (42%), Positives = 51/80 (63%), Gaps = 1/80 (1%)
 Frame = +3

Query: 255  HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKL-LQNDGCDIFVNLHKKQRQTLRK 431
            HPG TN FLV +++  A++YND SVLENHH A A+ L L     +  ++L   + +  R 
Sbjct: 825  HPGRTNAFLVATNAPQAVLYNDRSVLENHHAASAWNLYLSRPEYNFLLHLDHVEFKRFRF 884

Query: 432  MVIDMVLSTDMSKHMSLLAD 491
            +VI+ +L+TD+ KH   LA+
Sbjct: 885  LVIEAILATDLKKHFDFLAE 904



 Score = 44.4 bits (100), Expect = 5e-04
 Identities = 23/59 (38%), Positives = 30/59 (50%)
 Frame = +1

Query: 7   VAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTP 183
           V YT F    LL   +IP + F+ +   LE  Y RD P+HN +HA DV  +   L   P
Sbjct: 699 VMYTLFQDTGLLEIFKIPTQQFMNYFRALENGY-RDIPYHNRIHATDVLHAVWYLTTRP 756



 Score = 35.9 bits (79), Expect = 0.17
 Identities = 16/38 (42%), Positives = 22/38 (57%)
 Frame = +1

Query: 673  KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPL 786
            +GD E   G+ ISP  DR +  + K+   FI +IV PL
Sbjct: 962  QGDEEANLGLPISPFMDRSSPQLAKLQESFITHIVGPL 999


>EF108327-1|ABL14249.1|  502|Homo sapiens phosphodiesterase PDE7B2
           protein.
          Length = 502

 Score = 67.3 bits (157), Expect = 6e-11
 Identities = 31/78 (39%), Positives = 45/78 (57%)
 Frame = +1

Query: 22  FTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVF 201
           F +  L+   ++   T   F V ++E Y   NP+HN++HAADVTQ+ +  L  P L +  
Sbjct: 191 FNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFL 250

Query: 202 TPLEVCAALFAACVHDVD 255
           TPL++   L AA  HDVD
Sbjct: 251 TPLDIMLGLLAAAAHDVD 268



 Score = 54.0 bits (124), Expect = 6e-07
 Identities = 26/91 (28%), Positives = 49/91 (53%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG+   FL+ ++  LA +Y + SVLENHH      +L+     +  +L K+  Q + + 
Sbjct: 269 HPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRES--RLLAHLPKEMTQDIEQQ 326

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRKSRV 527
           +  ++L+TD+++    L  LK  +  +  R+
Sbjct: 327 LGSLILATDINRQNEFLTRLKAHLHNKDLRL 357



 Score = 35.5 bits (78), Expect = 0.22
 Identities = 14/39 (35%), Positives = 26/39 (66%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +G+ E++  ++ISP+C++   +I  I   F+ YIV PL+
Sbjct: 400 QGELEQKFELEISPLCNQQKDSIPSIQIGFMSYIVEPLF 438


>BC075083-1|AAH75083.1|  450|Homo sapiens phosphodiesterase 7B
           protein.
          Length = 450

 Score = 67.3 bits (157), Expect = 6e-11
 Identities = 31/78 (39%), Positives = 45/78 (57%)
 Frame = +1

Query: 22  FTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVF 201
           F +  L+   ++   T   F V ++E Y   NP+HN++HAADVTQ+ +  L  P L +  
Sbjct: 139 FNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFL 198

Query: 202 TPLEVCAALFAACVHDVD 255
           TPL++   L AA  HDVD
Sbjct: 199 TPLDIMLGLLAAAAHDVD 216



 Score = 54.0 bits (124), Expect = 6e-07
 Identities = 26/91 (28%), Positives = 49/91 (53%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG+   FL+ ++  LA +Y + SVLENHH      +L+     +  +L K+  Q + + 
Sbjct: 217 HPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRES--RLLAHLPKEMTQDIEQQ 274

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRKSRV 527
           +  ++L+TD+++    L  LK  +  +  R+
Sbjct: 275 LGSLILATDINRQNEFLTRLKAHLHNKDLRL 305



 Score = 35.5 bits (78), Expect = 0.22
 Identities = 14/39 (35%), Positives = 26/39 (66%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +G+ E++  ++ISP+C++   +I  I   F+ YIV PL+
Sbjct: 348 QGELEQKFELEISPLCNQQKDSIPSIQIGFMSYIVEPLF 386


>BC075082-1|AAH75082.1|  450|Homo sapiens phosphodiesterase 7B
           protein.
          Length = 450

 Score = 67.3 bits (157), Expect = 6e-11
 Identities = 31/78 (39%), Positives = 45/78 (57%)
 Frame = +1

Query: 22  FTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVF 201
           F +  L+   ++   T   F V ++E Y   NP+HN++HAADVTQ+ +  L  P L +  
Sbjct: 139 FNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFL 198

Query: 202 TPLEVCAALFAACVHDVD 255
           TPL++   L AA  HDVD
Sbjct: 199 TPLDIMLGLLAAAAHDVD 216



 Score = 54.0 bits (124), Expect = 6e-07
 Identities = 26/91 (28%), Positives = 49/91 (53%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG+   FL+ ++  LA +Y + SVLENHH      +L+     +  +L K+  Q + + 
Sbjct: 217 HPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRES--RLLAHLPKEMTQDIEQQ 274

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRKSRV 527
           +  ++L+TD+++    L  LK  +  +  R+
Sbjct: 275 LGSLILATDINRQNEFLTRLKAHLHNKDLRL 305



 Score = 35.5 bits (78), Expect = 0.22
 Identities = 14/39 (35%), Positives = 26/39 (66%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +G+ E++  ++ISP+C++   +I  I   F+ YIV PL+
Sbjct: 348 QGELEQKFELEISPLCNQQKDSIPSIQIGFMSYIVEPLF 386


>AL360178-1|CAH73075.1|  450|Homo sapiens phosphodiesterase 7B
           protein.
          Length = 450

 Score = 67.3 bits (157), Expect = 6e-11
 Identities = 31/78 (39%), Positives = 45/78 (57%)
 Frame = +1

Query: 22  FTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVF 201
           F +  L+   ++   T   F V ++E Y   NP+HN++HAADVTQ+ +  L  P L +  
Sbjct: 139 FNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFL 198

Query: 202 TPLEVCAALFAACVHDVD 255
           TPL++   L AA  HDVD
Sbjct: 199 TPLDIMLGLLAAAAHDVD 216



 Score = 54.0 bits (124), Expect = 6e-07
 Identities = 26/91 (28%), Positives = 49/91 (53%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG+   FL+ ++  LA +Y + SVLENHH      +L+     +  +L K+  Q + + 
Sbjct: 217 HPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRES--RLLAHLPKEMTQDIEQQ 274

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRKSRV 527
           +  ++L+TD+++    L  LK  +  +  R+
Sbjct: 275 LGSLILATDINRQNEFLTRLKAHLHNKDLRL 305



 Score = 35.5 bits (78), Expect = 0.22
 Identities = 14/39 (35%), Positives = 26/39 (66%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +G+ E++  ++ISP+C++   +I  I   F+ YIV PL+
Sbjct: 348 QGELEQKFELEISPLCNQQKDSIPSIQIGFMSYIVEPLF 386


>AL138828-4|CAI95287.1|  450|Homo sapiens phosphodiesterase 7B
           protein.
          Length = 450

 Score = 67.3 bits (157), Expect = 6e-11
 Identities = 31/78 (39%), Positives = 45/78 (57%)
 Frame = +1

Query: 22  FTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVF 201
           F +  L+   ++   T   F V ++E Y   NP+HN++HAADVTQ+ +  L  P L +  
Sbjct: 139 FNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFL 198

Query: 202 TPLEVCAALFAACVHDVD 255
           TPL++   L AA  HDVD
Sbjct: 199 TPLDIMLGLLAAAAHDVD 216



 Score = 54.0 bits (124), Expect = 6e-07
 Identities = 26/91 (28%), Positives = 49/91 (53%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG+   FL+ ++  LA +Y + SVLENHH      +L+     +  +L K+  Q + + 
Sbjct: 217 HPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRES--RLLAHLPKEMTQDIEQQ 274

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRKSRV 527
           +  ++L+TD+++    L  LK  +  +  R+
Sbjct: 275 LGSLILATDINRQNEFLTRLKAHLHNKDLRL 305



 Score = 35.5 bits (78), Expect = 0.22
 Identities = 14/39 (35%), Positives = 26/39 (66%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +G+ E++  ++ISP+C++   +I  I   F+ YIV PL+
Sbjct: 348 QGELEQKFELEISPLCNQQKDSIPSIQIGFMSYIVEPLF 386


>AL138828-3|CAI95286.1|  199|Homo sapiens phosphodiesterase 7B
           protein.
          Length = 199

 Score = 67.3 bits (157), Expect = 6e-11
 Identities = 31/78 (39%), Positives = 45/78 (57%)
 Frame = +1

Query: 22  FTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVF 201
           F +  L+   ++   T   F V ++E Y   NP+HN++HAADVTQ+ +  L  P L +  
Sbjct: 33  FNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFL 92

Query: 202 TPLEVCAALFAACVHDVD 255
           TPL++   L AA  HDVD
Sbjct: 93  TPLDIMLGLLAAAAHDVD 110


>AL133319-1|CAH73332.1|  450|Homo sapiens phosphodiesterase 7B
           protein.
          Length = 450

 Score = 67.3 bits (157), Expect = 6e-11
 Identities = 31/78 (39%), Positives = 45/78 (57%)
 Frame = +1

Query: 22  FTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVF 201
           F +  L+   ++   T   F V ++E Y   NP+HN++HAADVTQ+ +  L  P L +  
Sbjct: 139 FNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFL 198

Query: 202 TPLEVCAALFAACVHDVD 255
           TPL++   L AA  HDVD
Sbjct: 199 TPLDIMLGLLAAAAHDVD 216



 Score = 54.0 bits (124), Expect = 6e-07
 Identities = 26/91 (28%), Positives = 49/91 (53%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG+   FL+ ++  LA +Y + SVLENHH      +L+     +  +L K+  Q + + 
Sbjct: 217 HPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRES--RLLAHLPKEMTQDIEQQ 274

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRKSRV 527
           +  ++L+TD+++    L  LK  +  +  R+
Sbjct: 275 LGSLILATDINRQNEFLTRLKAHLHNKDLRL 305



 Score = 35.5 bits (78), Expect = 0.22
 Identities = 14/39 (35%), Positives = 26/39 (66%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +G+ E++  ++ISP+C++   +I  I   F+ YIV PL+
Sbjct: 348 QGELEQKFELEISPLCNQQKDSIPSIQIGFMSYIVEPLF 386


>AJ251860-1|CAB92441.1|  450|Homo sapiens phosphodiesterase 7B
           protein.
          Length = 450

 Score = 67.3 bits (157), Expect = 6e-11
 Identities = 31/78 (39%), Positives = 45/78 (57%)
 Frame = +1

Query: 22  FTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVF 201
           F +  L+   ++   T   F V ++E Y   NP+HN++HAADVTQ+ +  L  P L +  
Sbjct: 139 FNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFL 198

Query: 202 TPLEVCAALFAACVHDVD 255
           TPL++   L AA  HDVD
Sbjct: 199 TPLDIMLGLLAAAAHDVD 216



 Score = 54.0 bits (124), Expect = 6e-07
 Identities = 26/91 (28%), Positives = 49/91 (53%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG+   FL+ ++  LA +Y + SVLENHH      +L+     +  +L K+  Q + + 
Sbjct: 217 HPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRES--RLLAHLPKEMTQDIEQQ 274

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRKSRV 527
           +  ++L+TD+++    L  LK  +  +  R+
Sbjct: 275 LGSLILATDINRQNEFLTRLKAHLHNKDLRL 305



 Score = 35.5 bits (78), Expect = 0.22
 Identities = 14/39 (35%), Positives = 26/39 (66%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +G+ E++  ++ISP+C++   +I  I   F+ YIV PL+
Sbjct: 348 QGELEQKFELEISPLCNQQKDSIPSIQIGFMSYIVEPLF 386


>AB209990-1|BAE06072.1|  586|Homo sapiens PDE7B variant protein
           protein.
          Length = 586

 Score = 67.3 bits (157), Expect = 6e-11
 Identities = 31/78 (39%), Positives = 45/78 (57%)
 Frame = +1

Query: 22  FTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVF 201
           F +  L+   ++   T   F V ++E Y   NP+HN++HAADVTQ+ +  L  P L +  
Sbjct: 275 FNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFL 334

Query: 202 TPLEVCAALFAACVHDVD 255
           TPL++   L AA  HDVD
Sbjct: 335 TPLDIMLGLLAAAAHDVD 352



 Score = 54.0 bits (124), Expect = 6e-07
 Identities = 26/91 (28%), Positives = 49/91 (53%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG+   FL+ ++  LA +Y + SVLENHH      +L+     +  +L K+  Q + + 
Sbjct: 353 HPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRES--RLLAHLPKEMTQDIEQQ 410

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRKSRV 527
           +  ++L+TD+++    L  LK  +  +  R+
Sbjct: 411 LGSLILATDINRQNEFLTRLKAHLHNKDLRL 441



 Score = 35.5 bits (78), Expect = 0.22
 Identities = 14/39 (35%), Positives = 26/39 (66%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +G+ E++  ++ISP+C++   +I  I   F+ YIV PL+
Sbjct: 484 QGELEQKFELEISPLCNQQKDSIPSIQIGFMSYIVEPLF 522


>AB038040-1|BAA96537.1|  450|Homo sapiens cyclic nucleotide
           phosphodiesterase 7B protein.
          Length = 450

 Score = 67.3 bits (157), Expect = 6e-11
 Identities = 31/78 (39%), Positives = 45/78 (57%)
 Frame = +1

Query: 22  FTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVF 201
           F +  L+   ++   T   F V ++E Y   NP+HN++HAADVTQ+ +  L  P L +  
Sbjct: 139 FNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFL 198

Query: 202 TPLEVCAALFAACVHDVD 255
           TPL++   L AA  HDVD
Sbjct: 199 TPLDIMLGLLAAAAHDVD 216



 Score = 54.0 bits (124), Expect = 6e-07
 Identities = 26/91 (28%), Positives = 49/91 (53%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG+   FL+ ++  LA +Y + SVLENHH      +L+     +  +L K+  Q + + 
Sbjct: 217 HPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRES--RLLAHLPKEMTQDIEQQ 274

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRKSRV 527
           +  ++L+TD+++    L  LK  +  +  R+
Sbjct: 275 LGSLILATDINRQNEFLTRLKAHLHNKDLRL 305



 Score = 35.5 bits (78), Expect = 0.22
 Identities = 14/39 (35%), Positives = 26/39 (66%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +G+ E++  ++ISP+C++   +I  I   F+ YIV PL+
Sbjct: 348 QGELEQKFELEISPLCNQQKDSIPSIQIGFMSYIVEPLF 386


>U67932-1|AAB65772.1|  456|Homo sapiens cAMP phosphodiesterase PDE7
           protein.
          Length = 456

 Score = 61.3 bits (142), Expect = 4e-09
 Identities = 28/84 (33%), Positives = 45/84 (53%)
 Frame = +1

Query: 4   AVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTP 183
           ++ +  F+   L+    +       F V ++E Y   NP+HN++HAADVTQ+ +  L  P
Sbjct: 146 SLTFHLFSLHGLIEYFHLDMMKLRRFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEP 205

Query: 184 ALNAVFTPLEVCAALFAACVHDVD 255
            L    TP ++  +L AA  HD+D
Sbjct: 206 KLANSVTPWDILLSLIAAATHDLD 229



 Score = 58.8 bits (136), Expect = 2e-08
 Identities = 29/86 (33%), Positives = 51/86 (59%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG+   FL+ ++  LA +Y + SVLENHH   A  LL+  G  +F +L  + RQ +   
Sbjct: 230 HPGVNQPFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRESG--LFSHLPLESRQQMETQ 287

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           +  ++L+TD+S+    L+  ++ ++R
Sbjct: 288 IGALILATDISRQNEYLSLFRSHLDR 313



 Score = 43.2 bits (97), Expect = 0.001
 Identities = 16/39 (41%), Positives = 27/39 (69%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GD E+++ + +SP+CDRH  +I  I   F+ Y+V PL+
Sbjct: 361 QGDIEKKYHLGVSPLCDRHTESIANIQIGFMTYLVEPLF 399



 Score = 30.3 bits (65), Expect = 8.3
 Identities = 14/37 (37%), Positives = 21/37 (56%)
 Frame = +2

Query: 530 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           G L L++   R  VL+  + CAD+ NP +   L K+W
Sbjct: 314 GDLCLEDTRHRHLVLQMALKCADICNPCRTWELSKQW 350


>L12052-1|AAA35644.2|  482|Homo sapiens cAMP phosphodiesterase PDE7
           protein.
          Length = 482

 Score = 61.3 bits (142), Expect = 4e-09
 Identities = 28/84 (33%), Positives = 45/84 (53%)
 Frame = +1

Query: 4   AVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTP 183
           ++ +  F+   L+    +       F V ++E Y   NP+HN++HAADVTQ+ +  L  P
Sbjct: 172 SLTFHLFSLHGLIEYFHLDMMKLRRFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEP 231

Query: 184 ALNAVFTPLEVCAALFAACVHDVD 255
            L    TP ++  +L AA  HD+D
Sbjct: 232 KLANSVTPWDILLSLIAAATHDLD 255



 Score = 58.8 bits (136), Expect = 2e-08
 Identities = 29/86 (33%), Positives = 51/86 (59%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG+   FL+ ++  LA +Y + SVLENHH   A  LL+  G  +F +L  + RQ +   
Sbjct: 256 HPGVNQPFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRESG--LFSHLPLESRQQMETQ 313

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           +  ++L+TD+S+    L+  ++ ++R
Sbjct: 314 IGALILATDISRQNEYLSLFRSHLDR 339



 Score = 43.2 bits (97), Expect = 0.001
 Identities = 16/39 (41%), Positives = 27/39 (69%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GD E+++ + +SP+CDRH  +I  I   F+ Y+V PL+
Sbjct: 387 QGDIEKKYHLGVSPLCDRHTESIANIQIGFMTYLVEPLF 425



 Score = 30.3 bits (65), Expect = 8.3
 Identities = 14/37 (37%), Positives = 21/37 (56%)
 Frame = +2

Query: 530 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           G L L++   R  VL+  + CAD+ NP +   L K+W
Sbjct: 340 GDLCLEDTRHRHLVLQMALKCADICNPCRTWELSKQW 376


>BC126360-1|AAI26361.1|  456|Homo sapiens phosphodiesterase 7A
           protein.
          Length = 456

 Score = 61.3 bits (142), Expect = 4e-09
 Identities = 28/84 (33%), Positives = 45/84 (53%)
 Frame = +1

Query: 4   AVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTP 183
           ++ +  F+   L+    +       F V ++E Y   NP+HN++HAADVTQ+ +  L  P
Sbjct: 146 SLTFHLFSLHGLIEYFHLDMMKLRRFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEP 205

Query: 184 ALNAVFTPLEVCAALFAACVHDVD 255
            L    TP ++  +L AA  HD+D
Sbjct: 206 KLANSVTPWDILLSLIAAATHDLD 229



 Score = 58.8 bits (136), Expect = 2e-08
 Identities = 29/86 (33%), Positives = 51/86 (59%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG+   FL+ ++  LA +Y + SVLENHH   A  LL+  G  +F +L  + RQ +   
Sbjct: 230 HPGVNQPFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRESG--LFSHLPLESRQQMETQ 287

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           +  ++L+TD+S+    L+  ++ ++R
Sbjct: 288 IGALILATDISRQNEYLSLFRSHLDR 313



 Score = 43.2 bits (97), Expect = 0.001
 Identities = 16/39 (41%), Positives = 27/39 (69%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKISSRFIDYIVHPLW 789
           +GD E+++ + +SP+CDRH  +I  I   F+ Y+V PL+
Sbjct: 361 QGDIEKKYHLGVSPLCDRHTESIANIQIGFMTYLVEPLF 399



 Score = 30.3 bits (65), Expect = 8.3
 Identities = 14/37 (37%), Positives = 21/37 (56%)
 Frame = +2

Query: 530 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           G L L++   R  VL+  + CAD+ NP +   L K+W
Sbjct: 314 GDLCLEDTRHRHLVLQMALKCADICNPCRTWELSKQW 350


>AF332652-1|AAK57640.1|  424|Homo sapiens cAMP-specific cyclic
           nucleotide phosphodiesterase PDE7A3 protein.
          Length = 424

 Score = 61.3 bits (142), Expect = 4e-09
 Identities = 28/84 (33%), Positives = 45/84 (53%)
 Frame = +1

Query: 4   AVAYTAFTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTP 183
           ++ +  F+   L+    +       F V ++E Y   NP+HN++HAADVTQ+ +  L  P
Sbjct: 172 SLTFHLFSLHGLIEYFHLDMMKLRRFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEP 231

Query: 184 ALNAVFTPLEVCAALFAACVHDVD 255
            L    TP ++  +L AA  HD+D
Sbjct: 232 KLANSVTPWDILLSLIAAATHDLD 255



 Score = 58.8 bits (136), Expect = 2e-08
 Identities = 29/86 (33%), Positives = 51/86 (59%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           HPG+   FL+ ++  LA +Y + SVLENHH   A  LL+  G  +F +L  + RQ +   
Sbjct: 256 HPGVNQPFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRESG--LFSHLPLESRQQMETQ 313

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           +  ++L+TD+S+    L+  ++ ++R
Sbjct: 314 IGALILATDISRQNEYLSLFRSHLDR 339



 Score = 32.3 bits (70), Expect = 2.1
 Identities = 11/26 (42%), Positives = 19/26 (73%)
 Frame = +1

Query: 673 KGDREREHGMDISPMCDRHNATIRKI 750
           +GD E+++ + +SP+CDRH  +I  I
Sbjct: 387 QGDIEKKYHLGVSPLCDRHTESIANI 412



 Score = 30.3 bits (65), Expect = 8.3
 Identities = 14/37 (37%), Positives = 21/37 (56%)
 Frame = +2

Query: 530 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 640
           G L L++   R  VL+  + CAD+ NP +   L K+W
Sbjct: 340 GDLCLEDTRHRHLVLQMALKCADICNPCRTWELSKQW 376


>BC114431-1|AAI14432.1|  934|Homo sapiens phosphodiesterase 11A
           protein.
          Length = 934

 Score = 57.6 bits (133), Expect = 5e-08
 Identities = 27/86 (31%), Positives = 46/86 (53%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G  N F   S S LA +Y   + LE+HH   A  +LQ++G +IF NL  K+   L ++
Sbjct: 708 HRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQL 767

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           +   +L+TD++ +     +   +V +
Sbjct: 768 LKQSILATDLTLYFERRTEFFELVSK 793


>BC112393-1|AAI12394.1|  934|Homo sapiens phosphodiesterase 11A
           protein.
          Length = 934

 Score = 57.6 bits (133), Expect = 5e-08
 Identities = 27/86 (31%), Positives = 46/86 (53%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G  N F   S S LA +Y   + LE+HH   A  +LQ++G +IF NL  K+   L ++
Sbjct: 708 HRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQL 767

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           +   +L+TD++ +     +   +V +
Sbjct: 768 LKQSILATDLTLYFERRTEFFELVSK 793


>AJ278682-1|CAC15567.1|  684|Homo sapiens cAMP/cGMP cyclic
           nucleotide phosphodiesterase 11A3 protein.
          Length = 684

 Score = 57.6 bits (133), Expect = 5e-08
 Identities = 27/86 (31%), Positives = 46/86 (53%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G  N F   S S LA +Y   + LE+HH   A  +LQ++G +IF NL  K+   L ++
Sbjct: 458 HRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQL 517

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           +   +L+TD++ +     +   +V +
Sbjct: 518 LKQSILATDLTLYFERRTEFFELVSK 543


>AJ251509-1|CAB82573.1|  490|Homo sapiens cyclic nucleotide
           phosphodiesterase 11A1 protein.
          Length = 490

 Score = 57.6 bits (133), Expect = 5e-08
 Identities = 27/86 (31%), Positives = 46/86 (53%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G  N F   S S LA +Y   + LE+HH   A  +LQ++G +IF NL  K+   L ++
Sbjct: 264 HRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQL 323

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           +   +L+TD++ +     +   +V +
Sbjct: 324 LKQSILATDLTLYFERRTEFFELVSK 349


>AF281865-1|AAG32023.1|  576|Homo sapiens cAMP/cGMP
           phosphodiesterase 11A2 protein.
          Length = 576

 Score = 57.6 bits (133), Expect = 5e-08
 Identities = 27/86 (31%), Positives = 46/86 (53%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G  N F   S S LA +Y   + LE+HH   A  +LQ++G +IF NL  K+   L ++
Sbjct: 350 HRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQL 409

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           +   +L+TD++ +     +   +V +
Sbjct: 410 LKQSILATDLTLYFERRTEFFELVSK 435


>AB048423-3|BAB62714.1|  490|Homo sapiens phosphodiesterase 11A1
           protein.
          Length = 490

 Score = 57.6 bits (133), Expect = 5e-08
 Identities = 27/86 (31%), Positives = 46/86 (53%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G  N F   S S LA +Y   + LE+HH   A  +LQ++G +IF NL  K+   L ++
Sbjct: 264 HRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQL 323

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           +   +L+TD++ +     +   +V +
Sbjct: 324 LKQSILATDLTLYFERRTEFFELVSK 349


>AB048423-2|BAB62712.1|  934|Homo sapiens phosphodiesterase 11A4
           protein.
          Length = 934

 Score = 57.6 bits (133), Expect = 5e-08
 Identities = 27/86 (31%), Positives = 46/86 (53%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G  N F   S S LA +Y   + LE+HH   A  +LQ++G +IF NL  K+   L ++
Sbjct: 708 HRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQL 767

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           +   +L+TD++ +     +   +V +
Sbjct: 768 LKQSILATDLTLYFERRTEFFELVSK 793


>AB048423-1|BAB62713.2|  684|Homo sapiens phosphodiesterase 11A3
           protein.
          Length = 684

 Score = 57.6 bits (133), Expect = 5e-08
 Identities = 27/86 (31%), Positives = 46/86 (53%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G  N F   S S LA +Y   + LE+HH   A  +LQ++G +IF NL  K+   L ++
Sbjct: 458 HRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQL 517

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           +   +L+TD++ +     +   +V +
Sbjct: 518 LKQSILATDLTLYFERRTEFFELVSK 543


>AB038041-1|BAB16372.1|  684|Homo sapiens phosphodiesterase 11A3
           protein.
          Length = 684

 Score = 57.6 bits (133), Expect = 5e-08
 Identities = 27/86 (31%), Positives = 46/86 (53%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G  N F   S S LA +Y   + LE+HH   A  +LQ++G +IF NL  K+   L ++
Sbjct: 458 HRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQL 517

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           +   +L+TD++ +     +   +V +
Sbjct: 518 LKQSILATDLTLYFERRTEFFELVSK 543


>AB036704-1|BAB16371.1|  934|Homo sapiens phosphodiesterase 11A
           protein.
          Length = 934

 Score = 57.6 bits (133), Expect = 5e-08
 Identities = 27/86 (31%), Positives = 46/86 (53%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G  N F   S S LA +Y   + LE+HH   A  +LQ++G +IF NL  K+   L ++
Sbjct: 708 HRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQL 767

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVER 512
           +   +L+TD++ +     +   +V +
Sbjct: 768 LKQSILATDLTLYFERRTEFFELVSK 793


>AC012499-1|AAY14803.1|  325|Homo sapiens unknown protein.
          Length = 325

 Score = 56.8 bits (131), Expect = 8e-08
 Identities = 26/71 (36%), Positives = 41/71 (57%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G  N F   S S LA +Y   + LE+HH   A  +LQ++G +IF NL  K+   L ++
Sbjct: 252 HRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQL 311

Query: 435 VIDMVLSTDMS 467
           +   +L+TD++
Sbjct: 312 LKQSILATDLT 322


>X94354-1|CAA64079.1|  858|Homo sapiens cone cGMP phosphodiesterase
           protein.
          Length = 858

 Score = 51.2 bits (117), Expect = 4e-06
 Identities = 25/71 (35%), Positives = 45/71 (63%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G  N + + S+S LA ++   S+LE HHL  +  LLQ++  +IF NL+K+Q +T+  +
Sbjct: 606 HRGTNNLYQMKSTSPLARLHGS-SILERHHLEYSKTLLQDESLNIFQNLNKRQFETVIHL 664

Query: 435 VIDMVLSTDMS 467
               +++TD++
Sbjct: 665 FEVAIIATDLA 675


>U31973-1|AAA96392.1|  858|Homo sapiens phosphodiesterase A' subunit
           protein.
          Length = 858

 Score = 51.2 bits (117), Expect = 4e-06
 Identities = 25/71 (35%), Positives = 45/71 (63%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G  N + + S+S LA ++   S+LE HHL  +  LLQ++  +IF NL+K+Q +T+  +
Sbjct: 606 HRGTNNLYQMKSTSPLARLHGS-SILERHHLEYSKTLLQDESLNIFQNLNKRQFETVIHL 664

Query: 435 VIDMVLSTDMS 467
               +++TD++
Sbjct: 665 FEVAIIATDLA 675


>U20212-1|AAA92886.1|  858|Homo sapiens cone photoreceptor
           cGMP-phosphodiesterase alpha' subunit protein.
          Length = 858

 Score = 51.2 bits (117), Expect = 4e-06
 Identities = 25/71 (35%), Positives = 45/71 (63%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G  N + + S+S LA ++   S+LE HHL  +  LLQ++  +IF NL+K+Q +T+  +
Sbjct: 606 HRGTNNLYQMKSTSPLARLHGS-SILERHHLEYSKTLLQDESLNIFQNLNKRQFETVIHL 664

Query: 435 VIDMVLSTDMS 467
               +++TD++
Sbjct: 665 FEVAIIATDLA 675


>AL356214-7|CAH72330.1|  858|Homo sapiens phosphodiesterase 6C,
           cGMP-specific, cone, alpha prime protein.
          Length = 858

 Score = 51.2 bits (117), Expect = 4e-06
 Identities = 25/71 (35%), Positives = 45/71 (63%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G  N + + S+S LA ++   S+LE HHL  +  LLQ++  +IF NL+K+Q +T+  +
Sbjct: 606 HRGTNNLYQMKSTSPLARLHGS-SILERHHLEYSKTLLQDESLNIFQNLNKRQFETVIHL 664

Query: 435 VIDMVLSTDMS 467
               +++TD++
Sbjct: 665 FEVAIIATDLA 675


>AL157396-4|CAH73839.1|  858|Homo sapiens phosphodiesterase 6C,
           cGMP-specific, cone, alpha prime protein.
          Length = 858

 Score = 51.2 bits (117), Expect = 4e-06
 Identities = 25/71 (35%), Positives = 45/71 (63%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G  N + + S+S LA ++   S+LE HHL  +  LLQ++  +IF NL+K+Q +T+  +
Sbjct: 606 HRGTNNLYQMKSTSPLARLHGS-SILERHHLEYSKTLLQDESLNIFQNLNKRQFETVIHL 664

Query: 435 VIDMVLSTDMS 467
               +++TD++
Sbjct: 665 FEVAIIATDLA 675


>M26061-1|AAB69155.1|  860|Homo sapiens PDEA protein.
          Length = 860

 Score = 48.4 bits (110), Expect = 3e-05
 Identities = 24/89 (26%), Positives = 50/89 (56%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G  N + + S + LA ++   S+LE HHL     LL+++  +IF NL+++Q +    M
Sbjct: 603 HRGTNNLYQMKSQNPLAKLHGS-SILERHHLEFGKTLLRDESLNIFQNLNRRQHEHAIHM 661

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRKS 521
           +   +++TD++ +       + +V++ K+
Sbjct: 662 MDIAIIATDLALYFKKRTMFQKIVDQSKT 690


>BC035909-1|AAH35909.1|  860|Homo sapiens phosphodiesterase 6A,
           cGMP-specific, rod, alpha protein.
          Length = 860

 Score = 48.4 bits (110), Expect = 3e-05
 Identities = 24/89 (26%), Positives = 50/89 (56%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G  N + + S + LA ++   S+LE HHL     LL+++  +IF NL+++Q +    M
Sbjct: 603 HRGTNNLYQMKSQNPLAKLHGS-SILERHHLEFGKTLLRDESLNIFQNLNRRQHEHAIHM 661

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRKS 521
           +   +++TD++ +       + +V++ K+
Sbjct: 662 MDIAIIATDLALYFKKRTMFQKIVDQSKT 690


>X90587-1|CAA62215.1|  617|Homo sapiens Rod cGMP phosphodiesterase
           protein.
          Length = 617

 Score = 45.6 bits (103), Expect = 2e-04
 Identities = 23/89 (25%), Positives = 49/89 (55%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G  N + + S + LA ++   S+LE HHL     LL  +  +I+ NL+++Q + +  +
Sbjct: 364 HRGTNNLYQMKSQNPLAKLHGS-SILERHHLEFGKFLLSEETLNIYQNLNRRQHEHVIHL 422

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRKS 521
           +   +++TD++ +    A  + +V+  K+
Sbjct: 423 MDIAIIATDLALYFKKRAMFQKIVDESKN 451


>X66142-1|CAA46932.1|  854|Homo sapiens 3',5'-cyclic-nucleotide
           phosphodiesterase protein.
          Length = 854

 Score = 45.6 bits (103), Expect = 2e-04
 Identities = 23/89 (25%), Positives = 49/89 (55%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G  N + + S + LA ++   S+LE HHL     LL  +  +I+ NL+++Q + +  +
Sbjct: 601 HRGTNNLYQMKSQNPLAKLHGS-SILERHHLEFGKFLLSEETLNIYQNLNRRQHEHVIHL 659

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRKS 521
           +   +++TD++ +    A  + +V+  K+
Sbjct: 660 MDIAIIATDLALYFKKRAMFQKIVDESKN 688


>X62692-1|CAA44569.1|  854|Homo sapiens cGMP phosphodiesterase beta
           subunit protein.
          Length = 854

 Score = 45.6 bits (103), Expect = 2e-04
 Identities = 23/89 (25%), Positives = 49/89 (55%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G  N + + S + LA ++   S+LE HHL     LL  +  +I+ NL+++Q + +  +
Sbjct: 601 HRGTNNLYQMKSQNPLAKLHGS-SILERHHLEFGKFLLSEETLNIYQNLNRRQHEHVIHL 659

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRKS 521
           +   +++TD++ +    A  + +V+  K+
Sbjct: 660 MDIAIIATDLALYFKKRAMFQKIVDESKN 688


>S41458-1|AAB22690.1|  854|Homo sapiens rod cGMP phosphodiesterase
           beta-subunit protein.
          Length = 854

 Score = 45.6 bits (103), Expect = 2e-04
 Identities = 23/89 (25%), Positives = 49/89 (55%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G  N + + S + LA ++   S+LE HHL     LL  +  +I+ NL+++Q + +  +
Sbjct: 601 HRGTNNLYQMKSQNPLAKLHGS-SILERHHLEFGKFLLSEETLNIYQNLNRRQHEHVIHL 659

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRKS 521
           +   +++TD++ +    A  + +V+  K+
Sbjct: 660 MDIAIIATDLALYFKKRAMFQKIVDESKN 688


>BT009794-1|AAP88796.1|  853|Homo sapiens phosphodiesterase 6B,
           cGMP-specific, rod, beta (congenital stationary night
           bli protein.
          Length = 853

 Score = 44.8 bits (101), Expect = 4e-04
 Identities = 23/89 (25%), Positives = 48/89 (53%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G  N + + S + LA ++   S+LE HHL     LL  +  +I+ NL+++Q   +  +
Sbjct: 601 HRGTNNLYQMKSQNPLAKLHGS-SILERHHLEFGKFLLSEETLNIYQNLNRRQHDHVIHL 659

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRKS 521
           +   +++TD++ +    A  + +V+  K+
Sbjct: 660 MDIAIIATDLALYFKKRAMFQKIVDESKN 688


>BC000249-1|AAH00249.1|  853|Homo sapiens phosphodiesterase 6B,
           cGMP-specific, rod, beta (congenital stationary night
           bli protein.
          Length = 853

 Score = 44.8 bits (101), Expect = 4e-04
 Identities = 23/89 (25%), Positives = 48/89 (53%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNDGCDIFVNLHKKQRQTLRKM 434
           H G  N + + S + LA ++   S+LE HHL     LL  +  +I+ NL+++Q   +  +
Sbjct: 601 HRGTNNLYQMKSQNPLAKLHGS-SILERHHLEFGKFLLSEETLNIYQNLNRRQHDHVIHL 659

Query: 435 VIDMVLSTDMSKHMSLLADLKTMVERRKS 521
           +   +++TD++ +    A  + +V+  K+
Sbjct: 660 MDIAIIATDLALYFKKRAMFQKIVDESKN 688


>D89094-1|BAA28945.1|  875|Homo sapiens 3',5'-cyclic GMP
           phosphodiesterase protein.
          Length = 875

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 24/87 (27%), Positives = 42/87 (48%)
 Frame = +1

Query: 22  FTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVF 201
           FT   L+   Q+       + ++++++Y ++  +HN  HA +  Q     L    +    
Sbjct: 579 FTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKL 638

Query: 202 TPLEVCAALFAACVHDVDTRASPINSS 282
           T LE+ A L AA  HD+D R   +N+S
Sbjct: 639 TDLEILALLIAALSHDLDHRG--VNNS 663


>BC126233-1|AAI26234.1|  875|Homo sapiens phosphodiesterase 5A,
           cGMP-specific protein.
          Length = 875

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 24/87 (27%), Positives = 42/87 (48%)
 Frame = +1

Query: 22  FTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVF 201
           FT   L+   Q+       + ++++++Y ++  +HN  HA +  Q     L    +    
Sbjct: 579 FTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKL 638

Query: 202 TPLEVCAALFAACVHDVDTRASPINSS 282
           T LE+ A L AA  HD+D R   +N+S
Sbjct: 639 TDLEILALLIAALSHDLDHRG--VNNS 663


>AY264918-1|AAP21809.1|  833|Homo sapiens phosphodiesterase 5A
           protein.
          Length = 833

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 24/87 (27%), Positives = 42/87 (48%)
 Frame = +1

Query: 22  FTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVF 201
           FT   L+   Q+       + ++++++Y ++  +HN  HA +  Q     L    +    
Sbjct: 537 FTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKL 596

Query: 202 TPLEVCAALFAACVHDVDTRASPINSS 282
           T LE+ A L AA  HD+D R   +N+S
Sbjct: 597 TDLEILALLIAALSHDLDHRG--VNNS 621


>AJ004865-1|CAA06170.1|  875|Homo sapiens cGMP-binding,
           cGMP-specific phosphodiesterase (HSPDE5A1) protein.
          Length = 875

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 24/87 (27%), Positives = 42/87 (48%)
 Frame = +1

Query: 22  FTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVF 201
           FT   L+   Q+       + ++++++Y ++  +HN  HA +  Q     L    +    
Sbjct: 579 FTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKL 638

Query: 202 TPLEVCAALFAACVHDVDTRASPINSS 282
           T LE+ A L AA  HD+D R   +N+S
Sbjct: 639 TDLEILALLIAALSHDLDHRG--VNNS 663


>AF043731-1|AAC63967.1|  875|Homo sapiens cGMP-binding cGMP-specific
           3',5'-cyclic nucleotide phosphodiesterase protein.
          Length = 875

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 24/87 (27%), Positives = 42/87 (48%)
 Frame = +1

Query: 22  FTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVF 201
           FT   L+   Q+       + ++++++Y ++  +HN  HA +  Q     L    +    
Sbjct: 579 FTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKL 638

Query: 202 TPLEVCAALFAACVHDVDTRASPINSS 282
           T LE+ A L AA  HD+D R   +N+S
Sbjct: 639 TDLEILALLIAALSHDLDHRG--VNNS 663


>AC093752-1|AAY40985.1|  331|Homo sapiens unknown protein.
          Length = 331

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 24/87 (27%), Positives = 42/87 (48%)
 Frame = +1

Query: 22  FTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVF 201
           FT   L+   Q+       + ++++++Y ++  +HN  HA +  Q     L    +    
Sbjct: 35  FTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKL 94

Query: 202 TPLEVCAALFAACVHDVDTRASPINSS 282
           T LE+ A L AA  HD+D R   +N+S
Sbjct: 95  TDLEILALLIAALSHDLDHRG--VNNS 119


>AB001635-1|BAA33372.2|  875|Homo sapiens cGMP-binding cGMP-specific
           phosphodiesterase protein.
          Length = 875

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 24/87 (27%), Positives = 42/87 (48%)
 Frame = +1

Query: 22  FTSRELLTTLQIPARTFLAFAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVF 201
           FT   L+   Q+       + ++++++Y ++  +HN  HA +  Q     L    +    
Sbjct: 579 FTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKL 638

Query: 202 TPLEVCAALFAACVHDVDTRASPINSS 282
           T LE+ A L AA  HD+D R   +N+S
Sbjct: 639 TDLEILALLIAALSHDLDHRG--VNNS 663


>U86077-1|AAC51871.1|   71|Homo sapiens calmodulin-stimulated
           phosphodiesterase PDE1B1 protein.
          Length = 71

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 17/45 (37%), Positives = 28/45 (62%)
 Frame = +1

Query: 121 FHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVHDVD 255
           +HN +HAADVTQ+ +  L    +    + +E+ A +FAA +HD +
Sbjct: 1   YHNLIHAADVTQTVHCFLLRTGMVHCLSEIELLAIIFAAAIHDYE 45



 Score = 34.7 bits (76), Expect = 0.38
 Identities = 14/26 (53%), Positives = 18/26 (69%)
 Frame = +3

Query: 255 HPGLTNQFLVNSSSELALMYNDESVL 332
           H G TN F + + SE A++YND SVL
Sbjct: 46  HTGTTNSFHIQTKSECAIVYNDRSVL 71


>CR536567-1|CAG38804.1|  779|Homo sapiens PDE10A protein.
          Length = 779

 Score = 33.1 bits (72), Expect = 1.2
 Identities = 20/61 (32%), Positives = 31/61 (50%)
 Frame = +1

Query: 79  FAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVHDVDT 258
           F ++++++Y R  P+HN  HA  V      +L     + +FT LE    L A   HD+D 
Sbjct: 501 FIMSVKKNY-RRVPYHNWKHAVTVAHCMYAILQNN--HTLFTDLERKGLLIACLCHDLDH 557

Query: 259 R 261
           R
Sbjct: 558 R 558


>BC104860-1|AAI04861.1|  779|Homo sapiens phosphodiesterase 10A
           protein.
          Length = 779

 Score = 33.1 bits (72), Expect = 1.2
 Identities = 20/61 (32%), Positives = 31/61 (50%)
 Frame = +1

Query: 79  FAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVHDVDT 258
           F ++++++Y R  P+HN  HA  V      +L     + +FT LE    L A   HD+D 
Sbjct: 501 FIMSVKKNY-RRVPYHNWKHAVTVAHCMYAILQNN--HTLFTDLERKGLLIACLCHDLDH 557

Query: 259 R 261
           R
Sbjct: 558 R 558


>BC104858-1|AAI04859.1|  779|Homo sapiens phosphodiesterase 10A
           protein.
          Length = 779

 Score = 33.1 bits (72), Expect = 1.2
 Identities = 20/61 (32%), Positives = 31/61 (50%)
 Frame = +1

Query: 79  FAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVHDVDT 258
           F ++++++Y R  P+HN  HA  V      +L     + +FT LE    L A   HD+D 
Sbjct: 501 FIMSVKKNY-RRVPYHNWKHAVTVAHCMYAILQNN--HTLFTDLERKGLLIACLCHDLDH 557

Query: 259 R 261
           R
Sbjct: 558 R 558


>AL160160-1|CAH72023.1|  779|Homo sapiens phosphodiesterase 10A
           protein.
          Length = 779

 Score = 33.1 bits (72), Expect = 1.2
 Identities = 20/61 (32%), Positives = 31/61 (50%)
 Frame = +1

Query: 79  FAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVHDVDT 258
           F ++++++Y R  P+HN  HA  V      +L     + +FT LE    L A   HD+D 
Sbjct: 501 FIMSVKKNY-RRVPYHNWKHAVTVAHCMYAILQNN--HTLFTDLERKGLLIACLCHDLDH 557

Query: 259 R 261
           R
Sbjct: 558 R 558


>AL136130-1|CAI20436.1|  779|Homo sapiens phosphodiesterase 10A
           protein.
          Length = 779

 Score = 33.1 bits (72), Expect = 1.2
 Identities = 20/61 (32%), Positives = 31/61 (50%)
 Frame = +1

Query: 79  FAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVHDVDT 258
           F ++++++Y R  P+HN  HA  V      +L     + +FT LE    L A   HD+D 
Sbjct: 501 FIMSVKKNY-RRVPYHNWKHAVTVAHCMYAILQNN--HTLFTDLERKGLLIACLCHDLDH 557

Query: 259 R 261
           R
Sbjct: 558 R 558


>AL117345-1|CAB92797.2|  779|Homo sapiens phosphodiesterase 10A
           protein.
          Length = 779

 Score = 33.1 bits (72), Expect = 1.2
 Identities = 20/61 (32%), Positives = 31/61 (50%)
 Frame = +1

Query: 79  FAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVHDVDT 258
           F ++++++Y R  P+HN  HA  V      +L     + +FT LE    L A   HD+D 
Sbjct: 501 FIMSVKKNY-RRVPYHNWKHAVTVAHCMYAILQNN--HTLFTDLERKGLLIACLCHDLDH 557

Query: 259 R 261
           R
Sbjct: 558 R 558


>AL109778-1|CAB52432.1|  178|Homo sapiens PDE8A; phosphodiesterase
           8A protein.
          Length = 178

 Score = 33.1 bits (72), Expect = 1.2
 Identities = 17/51 (33%), Positives = 25/51 (49%)
 Frame = +2

Query: 494 EDDGRTKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVA 646
           E++G T K       +L    +R  +   L+ CAD+SNP +PL     W A
Sbjct: 41  EENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAA 91



 Score = 30.7 bits (66), Expect = 6.3
 Identities = 12/19 (63%), Positives = 18/19 (94%)
 Frame = +3

Query: 417 QTLRKMVIDMVLSTDMSKH 473
           +TLR+ +IDMVL+T+M+KH
Sbjct: 4   RTLRQGIIDMVLATEMTKH 22


>AL109687-1|CAB52020.1|  160|Homo sapiens PDE8A; phosphodiesterase
           8A protein.
          Length = 160

 Score = 33.1 bits (72), Expect = 1.2
 Identities = 17/51 (33%), Positives = 25/51 (49%)
 Frame = +2

Query: 494 EDDGRTKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVA 646
           E++G T K       +L    +R  +   L+ CAD+SNP +PL     W A
Sbjct: 23  EENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAA 73


>AF127480-1|AAD32596.1|  807|Homo sapiens 3',5'-cyclic nucleotide
           phosphodiesterase 10A2 protein.
          Length = 807

 Score = 33.1 bits (72), Expect = 1.2
 Identities = 20/61 (32%), Positives = 31/61 (50%)
 Frame = +1

Query: 79  FAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVHDVDT 258
           F ++++++Y R  P+HN  HA  V      +L     + +FT LE    L A   HD+D 
Sbjct: 529 FIMSVKKNY-RRVPYHNWKHAVTVAHCMYAILQNN--HTLFTDLERKGLLIACLCHDLDH 585

Query: 259 R 261
           R
Sbjct: 586 R 586


>AF127479-1|AAD32595.1|  779|Homo sapiens 3',5'-cyclic nucleotide
           phosphodiesterase 10A1 protein.
          Length = 779

 Score = 33.1 bits (72), Expect = 1.2
 Identities = 20/61 (32%), Positives = 31/61 (50%)
 Frame = +1

Query: 79  FAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVHDVDT 258
           F ++++++Y R  P+HN  HA  V      +L     + +FT LE    L A   HD+D 
Sbjct: 501 FIMSVKKNY-RRVPYHNWKHAVTVAHCMYAILQNN--HTLFTDLERKGLLIACLCHDLDH 557

Query: 259 R 261
           R
Sbjct: 558 R 558


>AB041798-3|BAB16383.1|  714|Homo sapiens phosphodiesterase 10A1
           (PDE10A1) protein.
          Length = 714

 Score = 33.1 bits (72), Expect = 1.2
 Identities = 20/61 (32%), Positives = 31/61 (50%)
 Frame = +1

Query: 79  FAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVHDVDT 258
           F ++++++Y R  P+HN  HA  V      +L     + +FT LE    L A   HD+D 
Sbjct: 436 FIMSVKKNY-RRVPYHNWKHAVTVAHCMYAILQNN--HTLFTDLERKGLLIACLCHDLDH 492

Query: 259 R 261
           R
Sbjct: 493 R 493


>AB026816-1|BAA84467.1|  789|Homo sapiens 3',5'-cyclic nucleotide
           phosphodiesterase 10A2 protein.
          Length = 789

 Score = 33.1 bits (72), Expect = 1.2
 Identities = 20/61 (32%), Positives = 31/61 (50%)
 Frame = +1

Query: 79  FAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVHDVDT 258
           F ++++++Y R  P+HN  HA  V      +L     + +FT LE    L A   HD+D 
Sbjct: 511 FIMSVKKNY-RRVPYHNWKHAVTVAHCMYAILQNN--HTLFTDLERKGLLIACLCHDLDH 567

Query: 259 R 261
           R
Sbjct: 568 R 568


>AB020593-1|BAA78034.1|  779|Homo sapiens 3',5'-Cyclic nucleotide
           phosphodiesterase protein.
          Length = 779

 Score = 33.1 bits (72), Expect = 1.2
 Identities = 20/61 (32%), Positives = 31/61 (50%)
 Frame = +1

Query: 79  FAVTLEEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVHDVDT 258
           F ++++++Y R  P+HN  HA  V      +L     + +FT LE    L A   HD+D 
Sbjct: 501 FIMSVKKNY-RRVPYHNWKHAVTVAHCMYAILQNN--HTLFTDLERKGLLIACLCHDLDH 557

Query: 259 R 261
           R
Sbjct: 558 R 558


>Y10260-1|CAA71309.1|  559|Homo sapiens EYA1A protein.
          Length = 559

 Score = 30.7 bits (66), Expect = 6.3
 Identities = 17/58 (29%), Positives = 29/58 (50%)
 Frame = +1

Query: 121 FHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVHDVDTRASPINSSSTPV 294
           +++S + A    S+N    TP+ NA +   E  + + +  V D     S I+S STP+
Sbjct: 197 YNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPI 254


>BC121799-1|AAI21800.1|  592|Homo sapiens eyes absent homolog 1
           (Drosophila) protein.
          Length = 592

 Score = 30.7 bits (66), Expect = 6.3
 Identities = 17/58 (29%), Positives = 29/58 (50%)
 Frame = +1

Query: 121 FHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVHDVDTRASPINSSSTPV 294
           +++S + A    S+N    TP+ NA +   E  + + +  V D     S I+S STP+
Sbjct: 230 YNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPI 287


>BC121798-1|AAI21799.1|  519|Homo sapiens EYA1 protein protein.
          Length = 519

 Score = 30.7 bits (66), Expect = 6.3
 Identities = 17/58 (29%), Positives = 29/58 (50%)
 Frame = +1

Query: 121 FHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVHDVDTRASPINSSSTPV 294
           +++S + A    S+N    TP+ NA +   E  + + +  V D     S I+S STP+
Sbjct: 157 YNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPI 214


>AK057294-1|BAB71413.1|  766|Homo sapiens protein ( Homo sapiens
           cDNA FLJ32732 fis, clone TESTI2001141, highly similar to
           Rattus norvegicus actin-filament binding protein Frabin
           mRNA. ).
          Length = 766

 Score = 30.7 bits (66), Expect = 6.3
 Identities = 18/67 (26%), Positives = 33/67 (49%)
 Frame = +2

Query: 392 RESSQETKTDPQENGYRHGPLDRYVETHESAGGSEDDGRTKKVAGSGVLLLDNYTDRIQV 571
           R +  ETK   +ENG     L++  + HE    +E   +  K+A   +L    Y +R+ +
Sbjct: 170 RGAETETKVQERENGESPLELEQLDQHHEMKETNEQ--KLHKIANELLLTERAYVNRLDL 227

Query: 572 LENLVHC 592
           L+ + +C
Sbjct: 228 LDQVFYC 234


>AJ000098-1|CAA03923.1|  592|Homo sapiens EYA1C protein.
          Length = 592

 Score = 30.7 bits (66), Expect = 6.3
 Identities = 17/58 (29%), Positives = 29/58 (50%)
 Frame = +1

Query: 121 FHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVHDVDTRASPINSSSTPV 294
           +++S + A    S+N    TP+ NA +   E  + + +  V D     S I+S STP+
Sbjct: 230 YNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPI 287


>AJ000097-1|CAA03922.1|  592|Homo sapiens EYA1B protein.
          Length = 592

 Score = 30.7 bits (66), Expect = 6.3
 Identities = 17/58 (29%), Positives = 29/58 (50%)
 Frame = +1

Query: 121 FHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVHDVDTRASPINSSSTPV 294
           +++S + A    S+N    TP+ NA +   E  + + +  V D     S I+S STP+
Sbjct: 230 YNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPI 287


>AF467247-1|AAL73437.1|  557|Homo sapiens EYA1D protein.
          Length = 557

 Score = 30.7 bits (66), Expect = 6.3
 Identities = 17/58 (29%), Positives = 29/58 (50%)
 Frame = +1

Query: 121 FHNSLHAADVTQSTNVLLNTPALNAVFTPLEVCAALFAACVHDVDTRASPINSSSTPV 294
           +++S + A    S+N    TP+ NA +   E  + + +  V D     S I+S STP+
Sbjct: 225 YNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPI 282


>AB002363-1|BAA20820.2| 1181|Homo sapiens KIAA0365 protein protein.
          Length = 1181

 Score = 30.3 bits (65), Expect = 8.3
 Identities = 20/44 (45%), Positives = 24/44 (54%), Gaps = 8/44 (18%)
 Frame = +2

Query: 236 PASTTSTPGPHQSI--PRQLQFRTRTNVQR------RVSPREPP 343
           PA    TP PH +   PRQ Q  TR++  R      R+SPREPP
Sbjct: 8   PARPCGTPTPHSARDRPRQPQRLTRSSRPRGERWGARLSPREPP 51


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 116,259,929
Number of Sequences: 237096
Number of extensions: 2606768
Number of successful extensions: 7124
Number of sequences better than 10.0: 227
Number of HSP's better than 10.0 without gapping: 6266
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7069
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9646050614
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)