Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= e40h0615
(776 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B605A Cluster: PREDICTED: similar to GA19489-PA... 61 3e-08
UniRef50_UPI0000DB72A4 Cluster: PREDICTED: similar to 3-phosphog... 56 1e-06
UniRef50_Q0W4A2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 51 3e-05
UniRef50_P35136 Cluster: D-3-phosphoglycerate dehydrogenase; n=8... 51 3e-05
UniRef50_UPI0000E4762C Cluster: PREDICTED: similar to D-3-phosph... 50 5e-05
UniRef50_A7SFV8 Cluster: Predicted protein; n=1; Nematostella ve... 50 5e-05
UniRef50_A7CYD6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 48 2e-04
UniRef50_Q97N23 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 48 3e-04
UniRef50_O43175 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 48 3e-04
UniRef50_A4ARG6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 48 3e-04
UniRef50_Q9X1C1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 47 6e-04
UniRef50_Q8XPB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 47 6e-04
UniRef50_A5GFY6 Cluster: Novel protein similar to vertebrate pho... 47 6e-04
UniRef50_A1IDH6 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 46 8e-04
UniRef50_A2U4T1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 46 0.001
UniRef50_A4MA79 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_Q8YIU3 Cluster: D-3-PHOSPHOGLYCERATE DEHYDROGENASE; n=7... 45 0.002
UniRef50_A0L7J1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 44 0.003
UniRef50_Q8PW48 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 44 0.006
UniRef50_O29445 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 44 0.006
UniRef50_Q4L766 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 43 0.007
UniRef50_Q1PZY1 Cluster: Similar to D-3-phosphoglycerate dehydro... 43 0.010
UniRef50_P40054 Cluster: D-3-phosphoglycerate dehydrogenase 1; n... 43 0.010
UniRef50_Q63VJ5 Cluster: D-3-phosphoglycerate dehydrogenase; n=8... 42 0.023
UniRef50_Q3AQU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 42 0.023
UniRef50_P0A9T3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 42 0.023
UniRef50_O33116 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 42 0.023
UniRef50_O04130 Cluster: D-3-phosphoglycerate dehydrogenase, chl... 42 0.023
UniRef50_Q897N8 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 41 0.030
UniRef50_P73821 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 41 0.030
UniRef50_Q7UQL2 Cluster: Phosphoglycerate dehydrogenase; n=2; Pl... 41 0.040
UniRef50_Q6A895 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 41 0.040
UniRef50_A1DFM4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 41 0.040
UniRef50_A6UQN3 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 41 0.040
UniRef50_Q82XE1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.052
UniRef50_Q5FUW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 40 0.052
UniRef50_Q4WHR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 40 0.052
UniRef50_A4R1I1 Cluster: Putative uncharacterized protein; n=1; ... 40 0.069
UniRef50_A6C9V4 Cluster: Phosphoglycerate dehydrogenase; n=1; Pl... 40 0.092
UniRef50_A5UQ03 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 40 0.092
UniRef50_Q1AXS3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 39 0.12
UniRef50_A3EWA5 Cluster: Phosphoglycerate dehydrogenase; n=2; Ba... 39 0.12
UniRef50_A7P9P5 Cluster: Chromosome chr3 scaffold_8, whole genom... 39 0.12
UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid ... 39 0.16
UniRef50_Q3SK87 Cluster: D-isomer specific 2-hydroxyacid dehydro... 39 0.16
UniRef50_Q3CIY1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 38 0.21
UniRef50_Q1IVI0 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 38 0.21
UniRef50_A7HDB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 38 0.21
UniRef50_A0LMX1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 38 0.21
UniRef50_Q5KN70 Cluster: D-3-phosphoglycerate dehydrogenase 2, p... 38 0.21
UniRef50_Q6L245 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 38 0.21
UniRef50_Q8R716 Cluster: Phosphoglycerate dehydrogenase and rela... 38 0.28
UniRef50_A6G5P3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 38 0.28
UniRef50_Q8ZTC7 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 38 0.37
UniRef50_Q8Y3L1 Cluster: Lmo2824 protein; n=14; Bacillales|Rep: ... 36 0.85
UniRef50_Q7WM64 Cluster: Putative dehydrogenase; n=2; Bordetella... 36 0.85
UniRef50_Q0J5C2 Cluster: Os08g0447000 protein; n=11; Viridiplant... 36 0.85
UniRef50_Q97ZK1 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 36 0.85
UniRef50_Q58424 Cluster: D-3-phosphoglycerate dehydrogenase; n=7... 36 0.85
UniRef50_Q8EN61 Cluster: Phosphoglycerate dehydrogenase; n=2; Ba... 36 1.5
UniRef50_Q83AZ4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 36 1.5
UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 36 1.5
UniRef50_Q9WYG2 Cluster: Phosphoglycerate dehydrogenase, putativ... 35 2.0
UniRef50_Q8UJZ6 Cluster: Phosphoglycerate dehydrogenase; n=3; Al... 35 2.0
UniRef50_A6Q7Q2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 35 2.0
UniRef50_Q5C1K5 Cluster: SJCHGC07734 protein; n=1; Schistosoma j... 35 2.0
UniRef50_Q9RUU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 35 2.6
UniRef50_Q46VE6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 35 2.6
UniRef50_Q9TXJ5 Cluster: D-3-phosphoglycerate dehydrogenase-like... 35 2.6
UniRef50_Q2LGV1 Cluster: Phosphoglycerate dehydrogenase; n=6; Ha... 35 2.6
UniRef50_Q67TJ9 Cluster: Phosphoglycerate dehydrogenase; n=1; Sy... 34 4.6
UniRef50_Q5ZYW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 34 4.6
UniRef50_Q3ZX05 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 34 4.6
UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 34 4.6
UniRef50_A0JVX0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 34 4.6
UniRef50_Q81N95 Cluster: D-3-phosphoglycerate dehydrogenase, put... 33 6.0
UniRef50_Q0C254 Cluster: D-isomer specific 2-hydroxyacid dehydro... 33 6.0
UniRef50_A7HEG1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 33 6.0
UniRef50_A3VA29 Cluster: D-isomer specific 2-hydroxyacid dehydro... 33 6.0
UniRef50_A4RX85 Cluster: Predicted protein; n=3; Ostreococcus|Re... 33 6.0
UniRef50_A7BQE7 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 33 8.0
UniRef50_A1HSQ7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 33 8.0
>UniRef50_UPI00015B605A Cluster: PREDICTED: similar to GA19489-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA19489-PA - Nasonia vitripennis
Length = 511
Score = 61.3 bits (142), Expect = 3e-08
Identities = 28/41 (68%), Positives = 33/41 (80%)
Frame = +3
Query: 3 PTDPVTLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLV 125
P +PVTLE+I+ P V+ATPHLGAST EAQ RV EIAEQ +
Sbjct: 266 PKNPVTLELIKHPKVVATPHLGASTAEAQTRVAIEIAEQFL 306
>UniRef50_UPI0000DB72A4 Cluster: PREDICTED: similar to
3-phosphoglycerate dehydrogenase; n=1; Apis
mellifera|Rep: PREDICTED: similar to 3-phosphoglycerate
dehydrogenase - Apis mellifera
Length = 478
Score = 55.6 bits (128), Expect = 1e-06
Identities = 27/48 (56%), Positives = 34/48 (70%)
Frame = +3
Query: 3 PTDPVTLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPGT 146
P + V LE+I P VI+TPHLGAST+EAQ RV +EIA+Q + L T
Sbjct: 266 PKNSVILELIAHPKVISTPHLGASTEEAQQRVAEEIAQQFLVLAGRST 313
>UniRef50_Q0W4A2 Cluster: D-3-phosphoglycerate dehydrogenase; n=11;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Uncultured methanogenic archaeon RC-I
Length = 526
Score = 51.2 bits (117), Expect = 3e-05
Identities = 23/42 (54%), Positives = 30/42 (71%)
Frame = +3
Query: 12 PVTLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVK 137
PV +++QP +I TPHLGAST EAQ+ V IAEQ++N K
Sbjct: 262 PVGSPLLEQPNIIVTPHLGASTAEAQINVAITIAEQVLNAFK 303
>UniRef50_P35136 Cluster: D-3-phosphoglycerate dehydrogenase; n=8;
Bacillaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus subtilis
Length = 525
Score = 51.2 bits (117), Expect = 3e-05
Identities = 21/42 (50%), Positives = 31/42 (73%)
Frame = +3
Query: 12 PVTLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVK 137
PV +++ P VIATPHLGASTKEAQ+ V +++E+++ K
Sbjct: 260 PVDNKLVDHPLVIATPHLGASTKEAQLNVAAQVSEEVLQFAK 301
>UniRef50_UPI0000E4762C Cluster: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase - Strongylocentrotus
purpuratus
Length = 493
Score = 50.4 bits (115), Expect = 5e-05
Identities = 25/39 (64%), Positives = 27/39 (69%)
Frame = +3
Query: 12 PVTLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVN 128
P +IQ P VI TPHLGAST EAQ RV EIAEQ V+
Sbjct: 230 PTYTALIQHPKVIVTPHLGASTVEAQERVACEIAEQFVD 268
>UniRef50_A7SFV8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 487
Score = 50.4 bits (115), Expect = 5e-05
Identities = 25/44 (56%), Positives = 33/44 (75%), Gaps = 3/44 (6%)
Frame = +3
Query: 6 TDPVT---LEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVN 128
T+P T ++++ P VIA PHLGAST+EAQ RV QEIA+Q V+
Sbjct: 264 TEPPTGSSADLVKHPKVIACPHLGASTEEAQRRVAQEIADQFVD 307
>UniRef50_A7CYD6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Opitutaceae bacterium TAV2|Rep: D-3-phosphoglycerate
dehydrogenase - Opitutaceae bacterium TAV2
Length = 529
Score = 48.4 bits (110), Expect = 2e-04
Identities = 23/40 (57%), Positives = 29/40 (72%)
Frame = +3
Query: 24 EIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPG 143
E+ P V+ TPHLGAST EAQ VG EIAEQ+ +++K G
Sbjct: 267 ELRALPNVVLTPHLGASTAEAQESVGIEIAEQIADVLKTG 306
>UniRef50_Q97N23 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
Clostridiaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Clostridium acetobutylicum
Length = 305
Score = 48.0 bits (109), Expect = 3e-04
Identities = 21/38 (55%), Positives = 26/38 (68%)
Frame = +3
Query: 24 EIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVK 137
EI+ P V TPH+GASTKEAQ R+G+EI + N K
Sbjct: 268 EILDNPRVSVTPHIGASTKEAQARIGEEIVNIVENTFK 305
>UniRef50_O43175 Cluster: D-3-phosphoglycerate dehydrogenase; n=53;
Bilateria|Rep: D-3-phosphoglycerate dehydrogenase - Homo
sapiens (Human)
Length = 533
Score = 48.0 bits (109), Expect = 3e-04
Identities = 22/37 (59%), Positives = 28/37 (75%)
Frame = +3
Query: 27 IIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVK 137
++ VI+ PHLGASTKEAQ R G+EIA Q V++VK
Sbjct: 272 LVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVK 308
>UniRef50_A4ARG6 Cluster: D-3-phosphoglycerate dehydrogenase; n=14;
Bacteroidetes|Rep: D-3-phosphoglycerate dehydrogenase -
Flavobacteriales bacterium HTCC2170
Length = 329
Score = 47.6 bits (108), Expect = 3e-04
Identities = 18/39 (46%), Positives = 30/39 (76%)
Frame = +3
Query: 21 LEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVK 137
++I+ P + TPH+GA+T EAQ R+G E+A Q+++L+K
Sbjct: 291 IKILMHPQISLTPHIGAATGEAQDRIGSELASQIISLLK 329
>UniRef50_Q9X1C1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Thermotogaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Thermotoga maritima
Length = 306
Score = 46.8 bits (106), Expect = 6e-04
Identities = 20/40 (50%), Positives = 29/40 (72%)
Frame = +3
Query: 3 PTDPVTLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQL 122
PTD + +++ V+ATPH+GAST EAQ RVG E+ E++
Sbjct: 261 PTDEIRRKLLSLDNVVATPHIGASTAEAQRRVGIELVEKI 300
>UniRef50_Q8XPB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Clostridium perfringens|Rep: D-3-phosphoglycerate
dehydrogenase - Clostridium perfringens
Length = 301
Score = 46.8 bits (106), Expect = 6e-04
Identities = 20/39 (51%), Positives = 30/39 (76%)
Frame = +3
Query: 21 LEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVK 137
LE+I P V TPH+GASTKEAQ+++G+E+ +N++K
Sbjct: 262 LELINHPKVSLTPHIGASTKEAQMKIGEEV----INIIK 296
>UniRef50_A5GFY6 Cluster: Novel protein similar to vertebrate
phosphoglycerate dehydrogenase; n=2; Eutheria|Rep: Novel
protein similar to vertebrate phosphoglycerate
dehydrogenase - Sus scrofa (Pig)
Length = 288
Score = 46.8 bits (106), Expect = 6e-04
Identities = 21/37 (56%), Positives = 28/37 (75%)
Frame = +3
Query: 27 IIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVK 137
++ VI+ PHLGAST+EAQ R G+EIA Q V++VK
Sbjct: 42 LVDHEKVISCPHLGASTREAQSRCGEEIAIQFVDMVK 78
>UniRef50_A1IDH6 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Deltaproteobacteria|Rep: D-3-phosphoglycerate
dehydrogenase - Candidatus Desulfococcus oleovorans Hxd3
Length = 532
Score = 46.4 bits (105), Expect = 8e-04
Identities = 21/34 (61%), Positives = 25/34 (73%)
Frame = +3
Query: 45 VIATPHLGASTKEAQVRVGQEIAEQLVNLVKPGT 146
VIATPHLGASTKEAQV V + A Q++ +K T
Sbjct: 276 VIATPHLGASTKEAQVNVAEAAAHQIIEFLKNNT 309
>UniRef50_A2U4T1 Cluster: D-3-phosphoglycerate dehydrogenase; n=14;
Bacillales|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus coagulans 36D1
Length = 541
Score = 46.0 bits (104), Expect = 0.001
Identities = 17/39 (43%), Positives = 31/39 (79%)
Frame = +3
Query: 15 VTLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNL 131
+T +++ P V TPHLGAST+EAQVRV +++++++++
Sbjct: 264 ITPGLLELPNVTVTPHLGASTREAQVRVAADVSDEIIHI 302
>UniRef50_A4MA79 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Petrotoga mobilis
SJ95|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Petrotoga mobilis SJ95
Length = 310
Score = 45.6 bits (103), Expect = 0.001
Identities = 21/38 (55%), Positives = 27/38 (71%)
Frame = +3
Query: 24 EIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVK 137
E+ P V+ TPH+GASTKEAQ RVG I +++V VK
Sbjct: 270 ELFALPNVVLTPHIGASTKEAQERVGINIVDRVVEEVK 307
>UniRef50_Q8YIU3 Cluster: D-3-PHOSPHOGLYCERATE DEHYDROGENASE; n=75;
Bacteria|Rep: D-3-PHOSPHOGLYCERATE DEHYDROGENASE -
Brucella melitensis
Length = 538
Score = 45.2 bits (102), Expect = 0.002
Identities = 22/47 (46%), Positives = 30/47 (63%), Gaps = 1/47 (2%)
Frame = +3
Query: 6 TDPVTL-EIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPG 143
T+P T E+ P V+ TPHLGAST EAQ V ++AEQ+ + + G
Sbjct: 267 TEPATENELFSLPNVVCTPHLGASTSEAQENVALQVAEQMSDYLVKG 313
>UniRef50_A0L7J1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Magnetococcus sp. (strain MC-1)
Length = 527
Score = 44.4 bits (100), Expect = 0.003
Identities = 21/39 (53%), Positives = 26/39 (66%)
Frame = +3
Query: 45 VIATPHLGASTKEAQVRVGQEIAEQLVNLVKPGTFPTLL 161
V+ATPHLG STKEAQ RV +IAEQ+ + + G L
Sbjct: 274 VVATPHLGGSTKEAQTRVAIQIAEQISDYLVSGVVKNAL 312
>UniRef50_Q8PW48 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Methanomicrobia|Rep: D-3-phosphoglycerate dehydrogenase
- Methanosarcina mazei (Methanosarcina frisia)
Length = 540
Score = 43.6 bits (98), Expect = 0.006
Identities = 20/45 (44%), Positives = 32/45 (71%)
Frame = +3
Query: 12 PVTLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPGT 146
P + ++ VI TPHLGAST+EAQV V +IA+++V+++ G+
Sbjct: 277 PFSSPLLNFDNVIVTPHLGASTQEAQVNVAIDIAKEVVSVLTGGS 321
>UniRef50_O29445 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Archaeoglobus fulgidus
Length = 527
Score = 43.6 bits (98), Expect = 0.006
Identities = 18/31 (58%), Positives = 24/31 (77%)
Frame = +3
Query: 45 VIATPHLGASTKEAQVRVGQEIAEQLVNLVK 137
V+ TPH+ AST+EAQ+ VG IAE +VN+ K
Sbjct: 273 VVTTPHIAASTREAQLNVGMIIAEDIVNMAK 303
>UniRef50_Q4L766 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Staphylococcus|Rep: D-3-phosphoglycerate dehydrogenase -
Staphylococcus haemolyticus (strain JCSC1435)
Length = 532
Score = 43.2 bits (97), Expect = 0.007
Identities = 17/44 (38%), Positives = 30/44 (68%)
Frame = +3
Query: 12 PVTLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPG 143
P +I+ +I TPHLGAST EAQ +V ++E+++++++ G
Sbjct: 264 PTDSPLIEHDKIIVTPHLGASTIEAQEKVAVSVSEEIIDILENG 307
>UniRef50_Q1PZY1 Cluster: Similar to D-3-phosphoglycerate
dehydrogenase; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similar to D-3-phosphoglycerate
dehydrogenase - Candidatus Kuenenia stuttgartiensis
Length = 535
Score = 42.7 bits (96), Expect = 0.010
Identities = 21/37 (56%), Positives = 26/37 (70%)
Frame = +3
Query: 12 PVTLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQL 122
P +++Q VIATPHLGAST+EAQ V E AEQ+
Sbjct: 271 PKDNKLLQLEEVIATPHLGASTEEAQYAVAIEAAEQM 307
>UniRef50_P40054 Cluster: D-3-phosphoglycerate dehydrogenase 1;
n=35; Eukaryota|Rep: D-3-phosphoglycerate dehydrogenase
1 - Saccharomyces cerevisiae (Baker's yeast)
Length = 469
Score = 42.7 bits (96), Expect = 0.010
Identities = 18/42 (42%), Positives = 26/42 (61%)
Frame = +3
Query: 18 TLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPG 143
T E++ P +I TPH+G ST+EAQ +G E+A L + G
Sbjct: 333 TSELVSLPNIILTPHIGGSTEEAQSSIGIEVATALSKYINEG 374
>UniRef50_Q63VJ5 Cluster: D-3-phosphoglycerate dehydrogenase; n=8;
Burkholderiaceae|Rep: D-3-phosphoglycerate dehydrogenase
- Burkholderia pseudomallei (Pseudomonas pseudomallei)
Length = 424
Score = 41.5 bits (93), Expect = 0.023
Identities = 17/35 (48%), Positives = 25/35 (71%)
Frame = +3
Query: 39 PAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPG 143
P VI TPH+G ST+EAQ +G+E++ +LV + G
Sbjct: 298 PNVILTPHIGGSTQEAQENIGEEVSSKLVAFLTRG 332
>UniRef50_Q3AQU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Chlorobium/Pelodictyon group|Rep: D-3-phosphoglycerate
dehydrogenase - Chlorobium chlorochromatii (strain CaD3)
Length = 538
Score = 41.5 bits (93), Expect = 0.023
Identities = 19/42 (45%), Positives = 28/42 (66%)
Frame = +3
Query: 18 TLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPG 143
T ++Q P VIATPH+ AST E Q +V ++AEQ++ + G
Sbjct: 276 THPLLQFPQVIATPHISASTAEGQEKVAIQMAEQIIAWKRDG 317
>UniRef50_P0A9T3 Cluster: D-3-phosphoglycerate dehydrogenase; n=185;
Bacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Shigella flexneri
Length = 410
Score = 41.5 bits (93), Expect = 0.023
Identities = 18/47 (38%), Positives = 29/47 (61%)
Frame = +3
Query: 6 TDPVTLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPGT 146
+DP T + + V+ TPH+G ST+EAQ +G E+A +L+ G+
Sbjct: 274 SDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYSDNGS 320
>UniRef50_O33116 Cluster: D-3-phosphoglycerate dehydrogenase; n=28;
Actinomycetales|Rep: D-3-phosphoglycerate dehydrogenase
- Mycobacterium leprae
Length = 528
Score = 41.5 bits (93), Expect = 0.023
Identities = 23/49 (46%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
Frame = +3
Query: 6 TDPVT-LEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPGTF 149
T+P T + + V+ TPHLGAST EAQ R G ++AE V L G F
Sbjct: 260 TEPCTDSPLFELSQVVVTPHLGASTAEAQDRAGTDVAES-VRLALAGEF 307
>UniRef50_O04130 Cluster: D-3-phosphoglycerate dehydrogenase,
chloroplast precursor; n=13; Magnoliophyta|Rep:
D-3-phosphoglycerate dehydrogenase, chloroplast
precursor - Arabidopsis thaliana (Mouse-ear cress)
Length = 624
Score = 41.5 bits (93), Expect = 0.023
Identities = 21/37 (56%), Positives = 24/37 (64%)
Frame = +3
Query: 27 IIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVK 137
+IQ V TPHLGASTKEAQ V EIAE + +K
Sbjct: 349 LIQHENVTVTPHLGASTKEAQEGVAIEIAEAVAGALK 385
>UniRef50_Q897N8 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Clostridiales|Rep: D-3-phosphoglycerate dehydrogenase -
Clostridium tetani
Length = 533
Score = 41.1 bits (92), Expect = 0.030
Identities = 18/43 (41%), Positives = 28/43 (65%)
Frame = +3
Query: 24 EIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPGTFP 152
++ + V+ TPH+GA+T EAQ VG IA+Q++N +K P
Sbjct: 270 DLYEYENVVVTPHIGATTIEAQQNVGVTIAKQVINGIKGDIVP 312
>UniRef50_P73821 Cluster: D-3-phosphoglycerate dehydrogenase; n=37;
Cyanobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Synechocystis sp. (strain PCC 6803)
Length = 554
Score = 41.1 bits (92), Expect = 0.030
Identities = 18/26 (69%), Positives = 22/26 (84%)
Frame = +3
Query: 45 VIATPHLGASTKEAQVRVGQEIAEQL 122
VI TPHLGAST+EAQV V ++AEQ+
Sbjct: 300 VILTPHLGASTEEAQVNVAVDVAEQI 325
>UniRef50_Q7UQL2 Cluster: Phosphoglycerate dehydrogenase; n=2;
Planctomycetaceae|Rep: Phosphoglycerate dehydrogenase -
Rhodopirellula baltica
Length = 540
Score = 40.7 bits (91), Expect = 0.040
Identities = 18/35 (51%), Positives = 24/35 (68%)
Frame = +3
Query: 39 PAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPG 143
P V+ TPHLGAST+EAQ +V E L+N ++ G
Sbjct: 273 PGVVCTPHLGASTEEAQTQVAVEGIHLLLNYLRTG 307
>UniRef50_Q6A895 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Actinomycetales|Rep: D-3-phosphoglycerate dehydrogenase
- Propionibacterium acnes
Length = 417
Score = 40.7 bits (91), Expect = 0.040
Identities = 18/45 (40%), Positives = 29/45 (64%)
Frame = +3
Query: 9 DPVTLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPG 143
+P + + VI TPH+G ST+EAQV +G+ +A +L++ V G
Sbjct: 286 EPFISPLREMDNVILTPHIGGSTQEAQVDIGRYVAGKLIDYVDNG 330
>UniRef50_A1DFM4 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
Fungi/Metazoa group|Rep: D-3-phosphoglycerate
dehydrogenase - Neosartorya fischeri (strain ATCC 1020 /
DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain
ATCC 1020 / DSM 3700 / NRRL 181))
Length = 582
Score = 40.7 bits (91), Expect = 0.040
Identities = 18/42 (42%), Positives = 27/42 (64%)
Frame = +3
Query: 27 IIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPGTFP 152
+I P + TPHLGAST EAQ V ++ EQ++ ++ G+ P
Sbjct: 278 LIAHPRAVVTPHLGASTVEAQENVSIDVCEQVLQILN-GSLP 318
>UniRef50_A6UQN3 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Methanococcus|Rep: D-3-phosphoglycerate dehydrogenase -
Methanococcus vannielii SB
Length = 523
Score = 40.7 bits (91), Expect = 0.040
Identities = 19/42 (45%), Positives = 26/42 (61%)
Frame = +3
Query: 12 PVTLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVK 137
P +I +I TPH GAST+EAQ+ G +AEQ V ++K
Sbjct: 261 PTKNPLISLNGLIGTPHQGASTEEAQLSAGTIVAEQTVKILK 302
>UniRef50_Q82XE1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=5; Proteobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Nitrosomonas
europaea
Length = 403
Score = 40.3 bits (90), Expect = 0.052
Identities = 18/37 (48%), Positives = 25/37 (67%)
Frame = +3
Query: 33 QQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPG 143
QQ AV+ PHLGAST+EA+ IA+Q+++ V G
Sbjct: 270 QQQAVVTLPHLGASTREAEENCAMMIADQIMDYVTNG 306
>UniRef50_Q5FUW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=55;
Bacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 416
Score = 40.3 bits (90), Expect = 0.052
Identities = 18/34 (52%), Positives = 24/34 (70%)
Frame = +3
Query: 45 VIATPHLGASTKEAQVRVGQEIAEQLVNLVKPGT 146
VI TPH+G ST EAQ R+G E+A +LV+ G+
Sbjct: 288 VILTPHIGGSTMEAQERIGVEVARKLVDYSDVGS 321
>UniRef50_Q4WHR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Aspergillus fumigatus|Rep: D-3-phosphoglycerate
dehydrogenase - Aspergillus fumigatus (Sartorya
fumigata)
Length = 635
Score = 40.3 bits (90), Expect = 0.052
Identities = 17/42 (40%), Positives = 27/42 (64%)
Frame = +3
Query: 27 IIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPGTFP 152
++ P + TPHLGAST EAQ V ++ EQ++ ++ G+ P
Sbjct: 329 LVAHPRAVVTPHLGASTVEAQENVSIDVCEQVLQILN-GSLP 369
>UniRef50_A4R1I1 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 421
Score = 39.9 bits (89), Expect = 0.069
Identities = 16/33 (48%), Positives = 23/33 (69%)
Frame = +3
Query: 45 VIATPHLGASTKEAQVRVGQEIAEQLVNLVKPG 143
+I TPH+G ST+EAQ +G E+A+ LV + G
Sbjct: 310 IILTPHIGGSTEEAQRAIGVEVADALVRYINQG 342
>UniRef50_A6C9V4 Cluster: Phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: Phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 541
Score = 39.5 bits (88), Expect = 0.092
Identities = 19/35 (54%), Positives = 22/35 (62%)
Frame = +3
Query: 12 PVTLEIIQQPAVIATPHLGASTKEAQVRVGQEIAE 116
P +I P ++ATPHLGAST EAQ V E AE
Sbjct: 264 PENRRLIDAPNMLATPHLGASTDEAQEMVALEAAE 298
>UniRef50_A5UQ03 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Chloroflexi (class)|Rep: D-3-phosphoglycerate
dehydrogenase - Roseiflexus sp. RS-1
Length = 524
Score = 39.5 bits (88), Expect = 0.092
Identities = 19/45 (42%), Positives = 27/45 (60%)
Frame = +3
Query: 12 PVTLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPGT 146
PV ++ P VI PHLGAST EAQ G ++AE ++ + G+
Sbjct: 261 PVGNPLVGHPRVITLPHLGASTVEAQALTGVDVAEGVLVALAGGS 305
>UniRef50_Q1AXS3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep:
D-3-phosphoglycerate dehydrogenase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 527
Score = 39.1 bits (87), Expect = 0.12
Identities = 18/28 (64%), Positives = 20/28 (71%)
Frame = +3
Query: 39 PAVIATPHLGASTKEAQVRVGQEIAEQL 122
P V+ TPHLGAST EAQ R G AEQ+
Sbjct: 270 PNVVVTPHLGASTAEAQDRAGVTAAEQV 297
>UniRef50_A3EWA5 Cluster: Phosphoglycerate dehydrogenase; n=2;
Bacteria|Rep: Phosphoglycerate dehydrogenase -
Leptospirillum sp. Group II UBA
Length = 535
Score = 39.1 bits (87), Expect = 0.12
Identities = 18/44 (40%), Positives = 28/44 (63%)
Frame = +3
Query: 12 PVTLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPG 143
P +++ I+TPH+GA+TKEAQ V IA+Q+V+ + G
Sbjct: 266 PADHPLLKLDNFISTPHIGAATKEAQENVALAIADQMVDYLGKG 309
>UniRef50_A7P9P5 Cluster: Chromosome chr3 scaffold_8, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr3 scaffold_8, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 653
Score = 39.1 bits (87), Expect = 0.12
Identities = 21/42 (50%), Positives = 25/42 (59%)
Frame = +3
Query: 12 PVTLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVK 137
P ++I V TPHLGAST EAQ V EIAE +V +K
Sbjct: 373 PKDSKLILHENVTVTPHLGASTMEAQEGVAIEIAEAVVGALK 414
>UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Ignicoccus hospitalis
KIN4/I|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Ignicoccus hospitalis
KIN4/I
Length = 308
Score = 38.7 bits (86), Expect = 0.16
Identities = 16/41 (39%), Positives = 26/41 (63%)
Frame = +3
Query: 3 PTDPVTLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLV 125
P L++I+ P AT H+GA T+EAQ R E+A++++
Sbjct: 262 PKSEELLKLIRHPRTFATAHIGAQTEEAQRRTSLEVAQRIL 302
>UniRef50_Q3SK87 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=4; Proteobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Thiobacillus
denitrificans (strain ATCC 25259)
Length = 391
Score = 38.7 bits (86), Expect = 0.16
Identities = 17/35 (48%), Positives = 24/35 (68%)
Frame = +3
Query: 39 PAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPG 143
P V+A PHLGAST+EA+ +AEQL + ++ G
Sbjct: 267 PKVVALPHLGASTEEAEENCAVMVAEQLTDYLENG 301
>UniRef50_Q3CIY1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=2;
Thermoanaerobacter ethanolicus|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Thermoanaerobacter ethanolicus ATCC 33223
Length = 319
Score = 38.3 bits (85), Expect = 0.21
Identities = 16/50 (32%), Positives = 29/50 (58%)
Frame = +3
Query: 12 PVTLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPGTFPTLL 161
P+ L + P VI TPH+G +T E+ R+G + ++ ++K T P ++
Sbjct: 267 PMHLPLFDLPNVILTPHIGGTTVESNKRMGNTAVDNVIAVLKGETPPNIV 316
>UniRef50_Q1IVI0 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Acidobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Acidobacteria bacterium (strain Ellin345)
Length = 531
Score = 38.3 bits (85), Expect = 0.21
Identities = 18/35 (51%), Positives = 24/35 (68%)
Frame = +3
Query: 39 PAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPG 143
P VI TPH+G ST EAQ VG +IA Q+ + ++ G
Sbjct: 272 PNVILTPHIGGSTAEAQDAVGVQIAHQVRDYLQRG 306
>UniRef50_A7HDB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Anaeromyxobacter sp. Fw109-5
Length = 528
Score = 38.3 bits (85), Expect = 0.21
Identities = 18/33 (54%), Positives = 23/33 (69%)
Frame = +3
Query: 45 VIATPHLGASTKEAQVRVGQEIAEQLVNLVKPG 143
VI TPH+GAST+EAQ V +AEQL + + G
Sbjct: 275 VILTPHIGASTEEAQSAVAVAVAEQLADYLVRG 307
>UniRef50_A0LMX1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep:
D-3-phosphoglycerate dehydrogenase - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 525
Score = 38.3 bits (85), Expect = 0.21
Identities = 19/44 (43%), Positives = 28/44 (63%)
Frame = +3
Query: 12 PVTLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPG 143
PV +++ VI TPHLGAS+ +AQ V + IA Q+V+ + G
Sbjct: 262 PVDSPLLKLENVIFTPHLGASSYQAQANVARAIATQIVDYLLYG 305
>UniRef50_Q5KN70 Cluster: D-3-phosphoglycerate dehydrogenase 2,
putative; n=2; Filobasidiella neoformans|Rep:
D-3-phosphoglycerate dehydrogenase 2, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 508
Score = 38.3 bits (85), Expect = 0.21
Identities = 16/36 (44%), Positives = 23/36 (63%)
Frame = +3
Query: 39 PAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPGT 146
P +I TPH+G ST+EAQ +G E++ L + GT
Sbjct: 379 PNLILTPHIGGSTEEAQRAIGTEVSNALTRYLNYGT 414
>UniRef50_Q6L245 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Thermoplasmatales|Rep: D-3-phosphoglycerate
dehydrogenase - Picrophilus torridus
Length = 299
Score = 38.3 bits (85), Expect = 0.21
Identities = 16/34 (47%), Positives = 24/34 (70%)
Frame = +3
Query: 24 EIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLV 125
E+++ P VI TPHLGA T+EAQ R+ A+ ++
Sbjct: 262 EMLKLPNVIITPHLGAQTREAQKRIAIMTADNII 295
>UniRef50_Q8R716 Cluster: Phosphoglycerate dehydrogenase and related
dehydrogenases; n=5; Clostridia|Rep: Phosphoglycerate
dehydrogenase and related dehydrogenases -
Thermoanaerobacter tengcongensis
Length = 533
Score = 37.9 bits (84), Expect = 0.28
Identities = 15/45 (33%), Positives = 29/45 (64%)
Frame = +3
Query: 27 IIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPGTFPTLL 161
+++ P V+ TPHLGAST EAQ + IA+++++ + + ++
Sbjct: 272 LLELPNVVFTPHLGASTYEAQENISIAIAQEVISALNGNLYGNIV 316
>UniRef50_A6G5P3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: D-3-phosphoglycerate
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 405
Score = 37.9 bits (84), Expect = 0.28
Identities = 16/33 (48%), Positives = 22/33 (66%)
Frame = +3
Query: 45 VIATPHLGASTKEAQVRVGQEIAEQLVNLVKPG 143
VI TPH+G ST+EAQ +G E++E L + G
Sbjct: 277 VILTPHIGGSTQEAQANIGVEVSEALAAYTRFG 309
>UniRef50_Q8ZTC7 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Thermoproteaceae|Rep: D-3-phosphoglycerate dehydrogenase
- Pyrobaculum aerophilum
Length = 307
Score = 37.5 bits (83), Expect = 0.37
Identities = 13/38 (34%), Positives = 26/38 (68%)
Frame = +3
Query: 24 EIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVK 137
++I V+ TPH+G+ TKEA +R+ +E+A + +++
Sbjct: 266 QLIAHEKVVVTPHVGSETKEAMMRLAEELAANIEEVIQ 303
>UniRef50_Q8Y3L1 Cluster: Lmo2824 protein; n=14; Bacillales|Rep:
Lmo2824 protein - Listeria monocytogenes
Length = 395
Score = 36.3 bits (80), Expect = 0.85
Identities = 17/47 (36%), Positives = 28/47 (59%)
Frame = +3
Query: 6 TDPVTLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPGT 146
TD T E++ V PHLGAST+EA+ + A++L + ++ G+
Sbjct: 252 TDFATKELLNHKKVHVFPHLGASTEEAETNCAKMAAKELQSYLETGS 298
>UniRef50_Q7WM64 Cluster: Putative dehydrogenase; n=2;
Bordetella|Rep: Putative dehydrogenase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 330
Score = 36.3 bits (80), Expect = 0.85
Identities = 15/51 (29%), Positives = 28/51 (54%)
Frame = +3
Query: 12 PVTLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPGTFPTLLA 164
P +++ P V+ PH G ST +A R + +AEQ++ +++ L+A
Sbjct: 269 PADHPLLRLPQVVLAPHAGGSTDQALARTARAVAEQVIEVLRDARPAHLIA 319
>UniRef50_Q0J5C2 Cluster: Os08g0447000 protein; n=11;
Viridiplantae|Rep: Os08g0447000 protein - Oryza sativa
subsp. japonica (Rice)
Length = 666
Score = 36.3 bits (80), Expect = 0.85
Identities = 18/38 (47%), Positives = 24/38 (63%)
Frame = +3
Query: 24 EIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVK 137
+++ V TPHLGAST EAQ V EIAE +V ++
Sbjct: 388 KLVLHENVTVTPHLGASTVEAQEGVAIEIAEAVVGALR 425
>UniRef50_Q97ZK1 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Sulfolobaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Sulfolobus solfataricus
Length = 326
Score = 36.3 bits (80), Expect = 0.85
Identities = 16/45 (35%), Positives = 26/45 (57%)
Frame = +3
Query: 3 PTDPVTLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVK 137
P + +++++ VI T H+GA TKEAQ RV + L+ +K
Sbjct: 276 PKEDWEIKLLRHERVIVTTHIGAQTKEAQHRVAVVTTDNLITALK 320
>UniRef50_Q58424 Cluster: D-3-phosphoglycerate dehydrogenase; n=7;
Euryarchaeota|Rep: D-3-phosphoglycerate dehydrogenase -
Methanococcus jannaschii
Length = 524
Score = 36.3 bits (80), Expect = 0.85
Identities = 16/31 (51%), Positives = 22/31 (70%)
Frame = +3
Query: 45 VIATPHLGASTKEAQVRVGQEIAEQLVNLVK 137
VI TPH GAST+EAQ G +AEQ+ +++
Sbjct: 273 VIGTPHQGASTEEAQKAAGTIVAEQIKKVLR 303
>UniRef50_Q8EN61 Cluster: Phosphoglycerate dehydrogenase; n=2;
Bacillaceae|Rep: Phosphoglycerate dehydrogenase -
Oceanobacillus iheyensis
Length = 528
Score = 35.5 bits (78), Expect = 1.5
Identities = 15/34 (44%), Positives = 24/34 (70%)
Frame = +3
Query: 24 EIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLV 125
+++ P V+ATPHLGAST EAQ V +++ ++
Sbjct: 268 KLLTLPEVVATPHLGASTVEAQEVVAIDVSHDVL 301
>UniRef50_Q83AZ4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=11; Bacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Coxiella burnetii
Length = 388
Score = 35.5 bits (78), Expect = 1.5
Identities = 16/35 (45%), Positives = 22/35 (62%)
Frame = +3
Query: 39 PAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPG 143
P VI PHLGASTKEA+ + EQ+ + ++ G
Sbjct: 266 PQVICLPHLGASTKEAEENCAIMVVEQVQDFLENG 300
>UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=15;
Actinobacteria (class)|Rep: D-3-phosphoglycerate
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 536
Score = 35.5 bits (78), Expect = 1.5
Identities = 15/26 (57%), Positives = 20/26 (76%)
Frame = +3
Query: 45 VIATPHLGASTKEAQVRVGQEIAEQL 122
V+ATPHLGAST EAQ + G +A+ +
Sbjct: 282 VVATPHLGASTDEAQEKAGIAVAKSV 307
>UniRef50_Q9WYG2 Cluster: Phosphoglycerate dehydrogenase, putative;
n=2; Thermotoga|Rep: Phosphoglycerate dehydrogenase,
putative - Thermotoga maritima
Length = 327
Score = 35.1 bits (77), Expect = 2.0
Identities = 20/56 (35%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
Frame = +3
Query: 27 IIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPGTFPTLLA--EVTRVLNK 188
+ + P +I T H+GA TKEA R+ A+ +V+ K G P + EV R+L +
Sbjct: 266 LFECPNLITTAHIGAHTKEAIFRMNMMAAQSIVDFFK-GRIPRYVVNKEVIRILKE 320
>UniRef50_Q8UJZ6 Cluster: Phosphoglycerate dehydrogenase; n=3;
Alphaproteobacteria|Rep: Phosphoglycerate dehydrogenase
- Agrobacterium tumefaciens (strain C58 / ATCC 33970)
Length = 354
Score = 35.1 bits (77), Expect = 2.0
Identities = 14/35 (40%), Positives = 22/35 (62%)
Frame = +3
Query: 33 QQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVK 137
Q ++ TPH+G T+EA VRVG + E + +V+
Sbjct: 300 QNQKIVVTPHIGGVTQEANVRVGVDAVEGIFAIVE 334
>UniRef50_A6Q7Q2 Cluster: D-3-phosphoglycerate dehydrogenase; n=27;
Epsilonproteobacteria|Rep: D-3-phosphoglycerate
dehydrogenase - Sulfurovum sp. (strain NBC37-1)
Length = 529
Score = 35.1 bits (77), Expect = 2.0
Identities = 16/39 (41%), Positives = 22/39 (56%)
Frame = +3
Query: 45 VIATPHLGASTKEAQVRVGQEIAEQLVNLVKPGTFPTLL 161
V TPHLGA+TKE+Q + + AE + K +P L
Sbjct: 278 VTVTPHLGANTKESQRNIAIQAAENAIAAAKGIAYPNAL 316
>UniRef50_Q5C1K5 Cluster: SJCHGC07734 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC07734 protein - Schistosoma
japonicum (Blood fluke)
Length = 199
Score = 35.1 bits (77), Expect = 2.0
Identities = 16/36 (44%), Positives = 25/36 (69%)
Frame = +3
Query: 24 EIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNL 131
+++Q P VIA+PHL + EAQ+RV +I+ L+ L
Sbjct: 3 KLLQHPNVIASPHLNEVSCEAQIRVAVDISRLLLLL 38
>UniRef50_Q9RUU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Deinococci|Rep: D-3-phosphoglycerate dehydrogenase -
Deinococcus radiodurans
Length = 544
Score = 34.7 bits (76), Expect = 2.6
Identities = 18/42 (42%), Positives = 27/42 (64%), Gaps = 2/42 (4%)
Frame = +3
Query: 9 DPVTLE--IIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVN 128
+P T E + P + T HLGA+T+EAQ RVG EI ++++
Sbjct: 276 EPPTAEHIFLGAPNLGITAHLGANTREAQERVGAEIVSRVLD 317
>UniRef50_Q46VE6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=6;
Proteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Ralstonia
eutropha (strain JMP134) (Alcaligenes eutrophus)
Length = 312
Score = 34.7 bits (76), Expect = 2.6
Identities = 16/40 (40%), Positives = 24/40 (60%)
Frame = +3
Query: 3 PTDPVTLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQL 122
P D V ++ P ++ TPH+G T+EA RV IAE++
Sbjct: 268 PADSVLADV---PNLVLTPHIGGVTREANARVSMMIAEKV 304
>UniRef50_Q9TXJ5 Cluster: D-3-phosphoglycerate dehydrogenase-like
protein; n=10; cellular organisms|Rep:
D-3-phosphoglycerate dehydrogenase-like protein -
Leishmania major
Length = 511
Score = 34.7 bits (76), Expect = 2.6
Identities = 16/33 (48%), Positives = 19/33 (57%)
Frame = +3
Query: 45 VIATPHLGASTKEAQVRVGQEIAEQLVNLVKPG 143
VI TPH+G ST EAQ +G E+ L V G
Sbjct: 388 VILTPHVGGSTCEAQEAIGVEVGTALAKFVTSG 420
>UniRef50_Q2LGV1 Cluster: Phosphoglycerate dehydrogenase; n=6;
Halobacteriaceae|Rep: Phosphoglycerate dehydrogenase -
Haloquadratum walsbyi
Length = 536
Score = 34.7 bits (76), Expect = 2.6
Identities = 14/26 (53%), Positives = 19/26 (73%)
Frame = +3
Query: 45 VIATPHLGASTKEAQVRVGQEIAEQL 122
++ TPHLGAST+ AQ V IA+Q+
Sbjct: 276 IVVTPHLGASTEAAQENVATSIADQI 301
>UniRef50_Q67TJ9 Cluster: Phosphoglycerate dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: Phosphoglycerate
dehydrogenase - Symbiobacterium thermophilum
Length = 540
Score = 33.9 bits (74), Expect = 4.6
Identities = 16/38 (42%), Positives = 23/38 (60%)
Frame = +3
Query: 39 PAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPGTFP 152
P V+ TPHL AST EAQ G+ IA+ ++ ++ P
Sbjct: 270 PNVVVTPHLSASTAEAQDANGRYIAQYVLRALRGELVP 307
>UniRef50_Q5ZYW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Legionella pneumophila|Rep: D-3-phosphoglycerate
dehydrogenase - Legionella pneumophila subsp.
pneumophila (strain Philadelphia 1 /ATCC 33152 / DSM
7513)
Length = 295
Score = 33.9 bits (74), Expect = 4.6
Identities = 15/34 (44%), Positives = 21/34 (61%)
Frame = +3
Query: 3 PTDPVTLEIIQQPAVIATPHLGASTKEAQVRVGQ 104
P P + + P +IATPH+G +T+EA V GQ
Sbjct: 248 PPLPANYSLWEVPNLIATPHIGFNTREALVAKGQ 281
>UniRef50_Q3ZX05 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Dehalococcoides|Rep: D-3-phosphoglycerate dehydrogenase
- Dehalococcoides sp. (strain CBDB1)
Length = 526
Score = 33.9 bits (74), Expect = 4.6
Identities = 13/29 (44%), Positives = 21/29 (72%)
Frame = +3
Query: 45 VIATPHLGASTKEAQVRVGQEIAEQLVNL 131
+I TPHLGAST EAQ ++ +Q++++
Sbjct: 272 IIVTPHLGASTAEAQELATSDVVKQVIDV 300
>UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Oceanicaulis alexandrii HTCC2633
Length = 407
Score = 33.9 bits (74), Expect = 4.6
Identities = 19/44 (43%), Positives = 24/44 (54%), Gaps = 2/44 (4%)
Frame = +3
Query: 45 VIATPHLGASTKEAQVRVGQEIAEQLVNLVKPG--TFPTLLAEV 170
VI TPH+G ST EAQ +G + A +L + G TF EV
Sbjct: 283 VILTPHIGGSTLEAQQAIGLDAAGKLARYLHEGSTTFAVNFPEV 326
>UniRef50_A0JVX0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Arthrobacter sp.
FB24|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Arthrobacter sp. (strain FB24)
Length = 319
Score = 33.9 bits (74), Expect = 4.6
Identities = 15/39 (38%), Positives = 21/39 (53%)
Frame = +3
Query: 12 PVTLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVN 128
P +I P VI TPH+G TKE+ R Q + L++
Sbjct: 277 PAPSRLITHPRVITTPHIGGYTKESVDRATQAAVDNLLH 315
>UniRef50_Q81N95 Cluster: D-3-phosphoglycerate dehydrogenase,
putative; n=19; Bacteria|Rep: D-3-phosphoglycerate
dehydrogenase, putative - Bacillus anthracis
Length = 390
Score = 33.5 bits (73), Expect = 6.0
Identities = 18/46 (39%), Positives = 24/46 (52%)
Frame = +3
Query: 6 TDPVTLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPG 143
TD +I+ V ATPHLGAST E++ A QL ++ G
Sbjct: 252 TDFPNENVIKMKNVTATPHLGASTSESEENCAVMAARQLREYLETG 297
>UniRef50_Q0C254 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=2;
Alphaproteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Hyphomonas neptunium
(strain ATCC 15444)
Length = 337
Score = 33.5 bits (73), Expect = 6.0
Identities = 19/47 (40%), Positives = 24/47 (51%)
Frame = +3
Query: 12 PVTLEIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPGTFP 152
PVT +I + VIA PH GAST EA R + A ++ G P
Sbjct: 277 PVTDALIARHDVIAAPHAGASTHEALARTNRIAALCAAEVIDGGNPP 323
>UniRef50_A7HEG1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=4; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase NAD-binding -
Anaeromyxobacter sp. Fw109-5
Length = 399
Score = 33.5 bits (73), Expect = 6.0
Identities = 16/44 (36%), Positives = 24/44 (54%)
Frame = +3
Query: 24 EIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPGTFPT 155
E+ + P V T H+GAST +AQ + +E + VK G P+
Sbjct: 270 ELAKLPNVYGTHHIGASTAQAQDAIARETVRIVEAFVKSGEVPS 313
>UniRef50_A3VA29 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase - Rhodobacterales bacterium
HTCC2654
Length = 301
Score = 33.5 bits (73), Expect = 6.0
Identities = 15/43 (34%), Positives = 24/43 (55%)
Frame = +3
Query: 39 PAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPGTFPTLLAE 167
P PH+G+ST E +VR+G + + + L + T P L+ E
Sbjct: 257 PNAFLLPHIGSSTVETRVRMGAILRDGFIALARGETPPNLVPE 299
>UniRef50_A4RX85 Cluster: Predicted protein; n=3; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 454
Score = 33.5 bits (73), Expect = 6.0
Identities = 16/53 (30%), Positives = 29/53 (54%)
Frame = +3
Query: 24 EIIQQPAVIATPHLGASTKEAQVRVGQEIAEQLVNLVKPGTFPTLLAEVTRVL 182
+++ P I PHLGAST+EA+ A+ +++ ++ GT + T +L
Sbjct: 299 DLMGHPRHIVLPHLGASTEEAEENSAAMAADTMMDFLETGTIRNSVNFPTTIL 351
>UniRef50_A7BQE7 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Beggiatoa sp. PS|Rep: D-3-phosphoglycerate dehydrogenase
- Beggiatoa sp. PS
Length = 302
Score = 33.1 bits (72), Expect = 8.0
Identities = 11/31 (35%), Positives = 21/31 (67%)
Frame = +3
Query: 45 VIATPHLGASTKEAQVRVGQEIAEQLVNLVK 137
++ TPH+GA T+E Q ++G +I +++ K
Sbjct: 272 IVVTPHIGAMTQETQEQIGLQIVKKIFEFFK 302
>UniRef50_A1HSQ7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Thermosinus
carboxydivorans Nor1|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Thermosinus
carboxydivorans Nor1
Length = 317
Score = 33.1 bits (72), Expect = 8.0
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +3
Query: 45 VIATPHLGASTKEAQVRVGQEIAEQLVNLV 134
V+ TPH GA+T EA R+G AE++V ++
Sbjct: 277 VVLTPHAGATTHEAVTRMGVMAAEEVVRVL 306
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 508,826,160
Number of Sequences: 1657284
Number of extensions: 7338973
Number of successful extensions: 16412
Number of sequences better than 10.0: 82
Number of HSP's better than 10.0 without gapping: 16034
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 16410
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 65438977305
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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