Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= e40h0445
(644 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_A7T6B8 Cluster: Predicted protein; n=1; Nematostella ve... 149 6e-35
UniRef50_P48163 Cluster: NADP-dependent malic enzyme; n=63; Euka... 146 4e-34
UniRef50_P06801 Cluster: NADP-dependent malic enzyme; n=52; cell... 146 5e-34
UniRef50_Q16798 Cluster: NADP-dependent malic enzyme, mitochondr... 143 3e-33
UniRef50_A2ZQ54 Cluster: Malic enzyme; n=9; Oryza sativa|Rep: Ma... 139 6e-32
UniRef50_Q4S0L0 Cluster: Malic enzyme; n=2; Tetraodon nigrovirid... 133 3e-30
UniRef50_P23368 Cluster: NAD-dependent malic enzyme, mitochondri... 132 9e-30
UniRef50_P16243 Cluster: NADP-dependent malic enzyme, chloroplas... 132 9e-30
UniRef50_A0L5P5 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 128 9e-29
UniRef50_A7CWP9 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 126 5e-28
UniRef50_Q89G76 Cluster: Malic enzyme; n=3; cellular organisms|R... 125 1e-27
UniRef50_A7PC00 Cluster: Chromosome chr2 scaffold_11, whole geno... 122 6e-27
UniRef50_Q0AIF8 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 120 2e-26
UniRef50_A1ZAF7 Cluster: Malic enzyme; n=5; Sophophora|Rep: Mali... 116 6e-25
UniRef50_A4RZU1 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 113 5e-24
UniRef50_A7IMB8 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 111 2e-23
UniRef50_Q8I8I4 Cluster: Malic enzyme; n=4; Eukaryota|Rep: Malic... 110 3e-23
UniRef50_A6SA55 Cluster: Malic enzyme; n=2; Sclerotiniaceae|Rep:... 110 3e-23
UniRef50_Q016K2 Cluster: NADP dependent malic enzyme; n=2; Ostre... 109 4e-23
UniRef50_Q86NT5 Cluster: Malic enzyme; n=2; Drosophila melanogas... 109 6e-23
UniRef50_Q4X1Z2 Cluster: NADP-dependent malic enzyme MaeA; n=11;... 107 3e-22
UniRef50_Q5BX10 Cluster: Malic enzyme; n=1; Schistosoma japonicu... 105 1e-21
UniRef50_Q8D911 Cluster: NAD-dependent malic enzyme; n=187; cell... 104 2e-21
UniRef50_Q01AM5 Cluster: NADP+-dependent malic enzyme; n=2; Ostr... 103 5e-21
UniRef50_A2EKE3 Cluster: Malic enzyme; n=14; Trichomonadidae|Rep... 103 5e-21
UniRef50_Q875H8 Cluster: Malic enzyme; n=1; Mucor circinelloides... 102 6e-21
UniRef50_P37221 Cluster: NAD-dependent malic enzyme 62 kDa isofo... 102 6e-21
UniRef50_P78715 Cluster: Malic enzyme, hydrogenosomal precursor;... 101 1e-20
UniRef50_Q4PC56 Cluster: Malic enzyme; n=1; Ustilago maydis|Rep:... 101 2e-20
UniRef50_A3BK03 Cluster: Malic enzyme; n=2; Oryza sativa|Rep: Ma... 100 3e-20
UniRef50_A3QW96 Cluster: Malic enzyme; n=10; Tigriopus californi... 99 1e-19
UniRef50_Q9HE50 Cluster: Malic enzyme; n=6; Pezizomycotina|Rep: ... 97 2e-19
UniRef50_UPI0000D9F768 Cluster: PREDICTED: similar to Y48B6A.12,... 96 6e-19
UniRef50_Q4QAQ6 Cluster: Malic enzyme, putative; n=20; Trypanoso... 95 1e-18
UniRef50_Q5CS07 Cluster: Malic enzyme; n=2; Cryptosporidium|Rep:... 95 2e-18
UniRef50_Q5K758 Cluster: Malic enzyme; n=1; Filobasidiella neofo... 94 3e-18
UniRef50_Q00XN9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 93 5e-18
UniRef50_Q5KEY3 Cluster: Malic enzyme; n=1; Filobasidiella neofo... 91 2e-17
UniRef50_A0Q531 Cluster: NAD-dependent malic enzyme; n=10; Franc... 91 3e-17
UniRef50_Q4T5P0 Cluster: Malic enzyme; n=1; Tetraodon nigrovirid... 88 1e-16
UniRef50_Q8Y5Y8 Cluster: Lmo1915 protein; n=15; Firmicutes|Rep: ... 88 1e-16
UniRef50_Q7SHJ8 Cluster: Malic enzyme; n=12; Pezizomycotina|Rep:... 88 1e-16
UniRef50_A2QY66 Cluster: Malic enzyme; n=2; cellular organisms|R... 88 1e-16
UniRef50_P36013 Cluster: NAD-dependent malic enzyme, mitochondri... 87 3e-16
UniRef50_P45868 Cluster: Probable NAD-dependent malic enzyme 2; ... 87 3e-16
UniRef50_A4SKB8 Cluster: NAD-dependent malic enzyme; n=2; Aeromo... 87 5e-16
UniRef50_A4RQC9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 85 2e-15
UniRef50_Q9RYN4 Cluster: Malate oxidoreductase; n=6; Deinococci|... 84 3e-15
UniRef50_A6XP71 Cluster: Malic enzyme protein 2; n=2; Mucoromyco... 83 7e-15
UniRef50_Q48796 Cluster: Malolactic enzyme; n=49; Bacteria|Rep: ... 83 7e-15
UniRef50_P40375 Cluster: NAD-dependent malic enzyme; n=3; Schizo... 82 1e-14
UniRef50_A1SVL3 Cluster: Malic enzyme aka malate dehydrogenase (... 81 2e-14
UniRef50_Q6AL43 Cluster: Related to NAD-dependent malic enzyme; ... 79 1e-13
UniRef50_Q7K3R0 Cluster: Malic enzyme; n=2; Sophophora|Rep: Mali... 78 2e-13
UniRef50_A3YYQ0 Cluster: Malate oxidoreductase; n=1; Synechococc... 77 5e-13
UniRef50_A5C6I9 Cluster: Malic enzyme; n=1; Vitis vinifera|Rep: ... 75 2e-12
UniRef50_Q95061 Cluster: Malic enzyme; n=2; Giardia intestinalis... 74 3e-12
UniRef50_Q5KBK5 Cluster: Nad-dependent malic enzyme, putative; n... 72 1e-11
UniRef50_Q5C370 Cluster: Malic enzyme; n=1; Schistosoma japonicu... 71 2e-11
UniRef50_Q27113 Cluster: Malic enzyme; n=1; Trichomonas vaginali... 66 7e-10
UniRef50_Q2HCG7 Cluster: Malic enzyme; n=1; Chaetomium globosum|... 62 1e-08
UniRef50_A7R628 Cluster: Chromosome undetermined scaffold_1141, ... 60 3e-08
UniRef50_A5B3Q7 Cluster: Malic enzyme; n=1; Vitis vinifera|Rep: ... 56 1e-06
UniRef50_Q8S484 Cluster: Putative NADP-dependent malic enzyme; n... 54 4e-06
UniRef50_Q3W7J3 Cluster: Malate dehydrogenase; n=1; Frankia sp. ... 42 0.017
UniRef50_Q8U225 Cluster: Malate oxidoreductase; n=41; cellular o... 42 0.017
UniRef50_Q5Y0M3 Cluster: Malate oxidoreductase; n=8; cellular or... 40 0.051
UniRef50_P54572 Cluster: Probable NAD-dependent malic enzyme 1; ... 40 0.051
UniRef50_Q2KKD0 Cluster: Oxalacetate decarboxylase; n=11; Lactob... 39 0.090
UniRef50_A0DE35 Cluster: Malic enzyme; n=3; Paramecium tetraurel... 39 0.090
UniRef50_A5C5G3 Cluster: Malic enzyme; n=1; Vitis vinifera|Rep: ... 38 0.16
UniRef50_Q9HKY7 Cluster: Malate oxidoreductase (Malic enzyme) re... 37 0.48
UniRef50_Q22974 Cluster: Putative uncharacterized protein; n=2; ... 36 1.1
UniRef50_Q0CJN2 Cluster: Predicted protein; n=3; Trichocomaceae|... 35 1.9
UniRef50_Q2STW7 Cluster: Putative uncharacterized protein; n=1; ... 34 2.6
UniRef50_Q87075 Cluster: Glycoprotein gX; n=1; Suid herpesvirus ... 34 3.4
UniRef50_Q8R7R6 Cluster: Malic enzyme; n=10; cellular organisms|... 34 3.4
UniRef50_Q5SLE4 Cluster: CBS domain protein; n=7; Bacteria|Rep: ... 34 3.4
UniRef50_Q0STR8 Cluster: Malate oxidoreductase; n=2; Clostridium... 34 3.4
UniRef50_Q3URU3 Cluster: ES cells cDNA, RIKEN full-length enrich... 33 4.5
UniRef50_A4AEE1 Cluster: Dihydroorotase and related cyclic amido... 33 4.5
UniRef50_A3EUF6 Cluster: ATP-dependent endonuclease; n=1; Leptos... 33 4.5
UniRef50_P16468 Cluster: NAD-dependent malic enzyme; n=32; Bacte... 33 4.5
UniRef50_UPI00006CF21C Cluster: Bowman-Birk serine protease inhi... 33 5.9
UniRef50_UPI0000DA40E4 Cluster: PREDICTED: hypothetical protein;... 33 7.8
UniRef50_Q1EI20 Cluster: Putative uncharacterized protein; n=2; ... 33 7.8
UniRef50_Q2Y6H5 Cluster: Response regulator receiver domain prot... 33 7.8
UniRef50_Q4Q3I8 Cluster: Putative uncharacterized protein; n=3; ... 33 7.8
UniRef50_P27536 Cluster: Posterior protein; n=4; Xenopus|Rep: Po... 33 7.8
>UniRef50_A7T6B8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 365
Score = 149 bits (361), Expect = 6e-35
Identities = 62/85 (72%), Positives = 75/85 (88%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIP 180
+K+G+++RRPRGLFI+IHDKGH+ D++ NWP T+V+AIV+TDGERILGLGDLG CGMGIP
Sbjct: 111 RKYGMIFRRPRGLFISIHDKGHIRDIVSNWPTTEVKAIVMTDGERILGLGDLGCCGMGIP 170
Query: 181 VGKLALYTALGGIKPHQCLPITIDV 255
VGKLALYT GGI P CLP+ IDV
Sbjct: 171 VGKLALYTVCGGIDPEGCLPVMIDV 195
Score = 58.4 bits (135), Expect = 1e-07
Identities = 23/40 (57%), Positives = 32/40 (80%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRR 374
GTN + +LDDP YIG+RQ+R DYDEL+DEF++A ++R
Sbjct: 196 GTNNEELLDDPFYIGVRQKRCNTEDYDELIDEFIQAALQR 235
>UniRef50_P48163 Cluster: NADP-dependent malic enzyme; n=63;
Eukaryota|Rep: NADP-dependent malic enzyme - Homo
sapiens (Human)
Length = 572
Score = 146 bits (354), Expect = 4e-34
Identities = 64/85 (75%), Positives = 72/85 (84%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GT + +L DPLYIGLRQRRVRG +YD+ LDEFM AV +YG NCL+QFEDF N NAFRL
Sbjct: 196 GTENEELLKDPLYIGLRQRRVRGSEYDDFLDEFMEAVSSKYGMNCLIQFEDFANVNAFRL 255
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAG 509
L KYRN+YCTFNDDIQGTA+VAVAG
Sbjct: 256 LNKYRNQYCTFNDDIQGTASVAVAG 280
Score = 138 bits (335), Expect = 8e-32
Identities = 60/85 (70%), Positives = 72/85 (84%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIP 180
Q++ LV+R+PRGLFITIHD+GH+ VL WPE ++AIVVTDGERILGLGDLG GMGIP
Sbjct: 111 QQYSLVFRKPRGLFITIHDRGHIASVLNAWPEDVIKAIVVTDGERILGLGDLGCNGMGIP 170
Query: 181 VGKLALYTALGGIKPHQCLPITIDV 255
VGKLALYTA GG+ P +CLP+ +DV
Sbjct: 171 VGKLALYTACGGMNPQECLPVILDV 195
>UniRef50_P06801 Cluster: NADP-dependent malic enzyme; n=52;
cellular organisms|Rep: NADP-dependent malic enzyme -
Mus musculus (Mouse)
Length = 572
Score = 146 bits (353), Expect = 5e-34
Identities = 64/85 (75%), Positives = 70/85 (82%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GT + +L DPLYIGLR RRVRGP+YD LDEFM A +YG NCL+QFEDF N NAFRL
Sbjct: 196 GTENEELLKDPLYIGLRHRRVRGPEYDAFLDEFMEAASSKYGMNCLIQFEDFANRNAFRL 255
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAG 509
L KYRNKYCTFNDDIQGTA+VAVAG
Sbjct: 256 LNKYRNKYCTFNDDIQGTASVAVAG 280
Score = 142 bits (343), Expect = 9e-33
Identities = 63/85 (74%), Positives = 72/85 (84%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIP 180
Q++ L +R+PRGLFI+IHDKGH+ VL WPE V+AIVVTDGERILGLGDLG GMGIP
Sbjct: 111 QQYSLAFRKPRGLFISIHDKGHIASVLNAWPEDVVKAIVVTDGERILGLGDLGCNGMGIP 170
Query: 181 VGKLALYTALGGIKPHQCLPITIDV 255
VGKLALYTA GG+ P QCLPIT+DV
Sbjct: 171 VGKLALYTACGGVNPQQCLPITLDV 195
>UniRef50_Q16798 Cluster: NADP-dependent malic enzyme, mitochondrial
precursor; n=15; Bilateria|Rep: NADP-dependent malic
enzyme, mitochondrial precursor - Homo sapiens (Human)
Length = 604
Score = 143 bits (347), Expect = 3e-33
Identities = 61/85 (71%), Positives = 73/85 (85%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIP 180
Q +GL +RRPRGLFITIHDKGH+ +L +WPE +++A+VVTDGERILGLGDLG GMGIP
Sbjct: 146 QHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIP 205
Query: 181 VGKLALYTALGGIKPHQCLPITIDV 255
VGKLALYTA GG+ P QCLP+ +DV
Sbjct: 206 VGKLALYTACGGVNPQQCLPVLLDV 230
Score = 140 bits (339), Expect = 3e-32
Identities = 62/85 (72%), Positives = 72/85 (84%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN + +L DPLYIGL+ +RV G YD+LLDEFM+AV ++G NCL+QFEDF NANAFRL
Sbjct: 231 GTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRL 290
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAG 509
L KYRNKYC FNDDIQGTA+VAVAG
Sbjct: 291 LNKYRNKYCMFNDDIQGTASVAVAG 315
>UniRef50_A2ZQ54 Cluster: Malic enzyme; n=9; Oryza sativa|Rep: Malic
enzyme - Oryza sativa subsp. japonica (Rice)
Length = 613
Score = 139 bits (336), Expect = 6e-32
Identities = 59/85 (69%), Positives = 75/85 (88%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIP 180
QK+G ++R+P+GL++++ DKG V DVL+NWPE +++ IVVTDGERILGLGDLG GMGIP
Sbjct: 196 QKYGSIFRQPQGLYVSLKDKGKVLDVLRNWPERNIQVIVVTDGERILGLGDLGCQGMGIP 255
Query: 181 VGKLALYTALGGIKPHQCLPITIDV 255
VGKL+LYTALGG++P CLPITIDV
Sbjct: 256 VGKLSLYTALGGVRPSACLPITIDV 280
Score = 111 bits (266), Expect = 2e-23
Identities = 50/85 (58%), Positives = 62/85 (72%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN + +L+D YIGLRQRR G +Y EL++EFM AV + YG+ L+QFEDF N NAF L
Sbjct: 281 GTNNEQLLNDEFYIGLRQRRATGKEYHELMEEFMSAVKQIYGEKVLIQFEDFANHNAFDL 340
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAG 509
L KY + FNDDIQGTA+V +AG
Sbjct: 341 LAKYSKSHLVFNDDIQGTASVVLAG 365
>UniRef50_Q4S0L0 Cluster: Malic enzyme; n=2; Tetraodon
nigroviridis|Rep: Malic enzyme - Tetraodon nigroviridis
(Green puffer)
Length = 694
Score = 133 bits (322), Expect = 3e-30
Identities = 69/143 (48%), Positives = 87/143 (60%), Gaps = 13/143 (9%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
G Q +LDDPLYIGL+ +RVRG DYD L++EFM+AV +YG NCL+QFEDF N+NAFR+
Sbjct: 253 GVCVQVLLDDPLYIGLKHKRVRGKDYDGLIEEFMQAVTDKYGMNCLIQFEDFANSNAFRI 312
Query: 435 LEKYRNKYCTFNDDIQGTAAVA------------VAGYSPVSDSHR-RGCPTTSSSSREP 575
L KYRN+YCTFNDDIQG A AG + +S H RGC + S +
Sbjct: 313 LNKYRNRYCTFNDDIQGGQQAARGLAEGGRPAGPPAGLTSLSFRHGVRGCGRSLGRSEDH 372
Query: 576 ERPLWVSRNCALWP*KGEGTPEA 644
+ P + C +GE P A
Sbjct: 373 QEPAQGAHLCVPGGRRGEAAPPA 395
Score = 116 bits (278), Expect = 6e-25
Identities = 49/66 (74%), Positives = 60/66 (90%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIP 180
Q++GL +RRPRGLFITIHD+GH+ +L +WPE D++A+VVTDGERILGLGDLG+ GMGIP
Sbjct: 158 QQYGLAFRRPRGLFITIHDRGHIATMLNSWPEEDIKAVVVTDGERILGLGDLGSYGMGIP 217
Query: 181 VGKLAL 198
VGKLAL
Sbjct: 218 VGKLAL 223
>UniRef50_P23368 Cluster: NAD-dependent malic enzyme, mitochondrial
precursor; n=53; Eumetazoa|Rep: NAD-dependent malic
enzyme, mitochondrial precursor - Homo sapiens (Human)
Length = 584
Score = 132 bits (318), Expect = 9e-30
Identities = 56/84 (66%), Positives = 70/84 (83%)
Frame = +1
Query: 4 KFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPV 183
++G ++RRP+GLFI+I D+GHV ++ NWPE V+A+VVTDGERILGLGDLG GMGIPV
Sbjct: 122 QYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIPV 181
Query: 184 GKLALYTALGGIKPHQCLPITIDV 255
GKL LYTA GI+P +CLP+ IDV
Sbjct: 182 GKLCLYTACAGIRPDRCLPVCIDV 205
Score = 130 bits (313), Expect = 4e-29
Identities = 57/85 (67%), Positives = 69/85 (81%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GT+ ++L DP Y+GL Q+R R YD+L+DEFM+A+ RYG+N L+QFEDFGN NAFR
Sbjct: 206 GTDNIALLKDPFYMGLYQKRDRTQQYDDLIDEFMKAITDRYGRNTLIQFEDFGNHNAFRF 265
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAG 509
L KYR KYCTFNDDIQGTAAVA+AG
Sbjct: 266 LRKYREKYCTFNDDIQGTAAVALAG 290
>UniRef50_P16243 Cluster: NADP-dependent malic enzyme, chloroplast
precursor; n=79; Magnoliophyta|Rep: NADP-dependent malic
enzyme, chloroplast precursor - Zea mays (Maize)
Length = 636
Score = 132 bits (318), Expect = 9e-30
Identities = 57/85 (67%), Positives = 71/85 (83%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIP 180
QK+G ++ RP+GL++++ DKG V +VL+NWP +++ I VTDGERILGLGDLG GMGIP
Sbjct: 193 QKYGSIFGRPQGLYVSLKDKGKVLEVLRNWPHRNIQVICVTDGERILGLGDLGCQGMGIP 252
Query: 181 VGKLALYTALGGIKPHQCLPITIDV 255
VGKLALYTALGG+ P CLPITIDV
Sbjct: 253 VGKLALYTALGGVDPSVCLPITIDV 277
Score = 114 bits (274), Expect = 2e-24
Identities = 51/85 (60%), Positives = 64/85 (75%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN + +L+D YIGLRQ+R G +YDEL++EFM AV + YG+ L+QFEDF N NAF L
Sbjct: 278 GTNNEFLLNDEFYIGLRQKRATGEEYDELIEEFMSAVKQFYGEKVLIQFEDFANHNAFDL 337
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAG 509
LEKY + FNDDIQGTA+V +AG
Sbjct: 338 LEKYSKSHLVFNDDIQGTASVVLAG 362
>UniRef50_A0L5P5 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=1;
Magnetococcus sp. MC-1|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Magnetococcus
sp. (strain MC-1)
Length = 556
Score = 128 bits (310), Expect = 9e-29
Identities = 57/85 (67%), Positives = 70/85 (82%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIP 180
Q +G ++RRP+G+FI+I+DKG + ++L NW DVR IVVTDG RILGLGDLGA GMGIP
Sbjct: 115 QTYGHIFRRPQGMFISINDKGRIAELLGNWVHKDVRVIVVTDGSRILGLGDLGAHGMGIP 174
Query: 181 VGKLALYTALGGIKPHQCLPITIDV 255
VGKLALYTAL GI P CLP+T+D+
Sbjct: 175 VGKLALYTALAGIPPIHCLPVTLDM 199
Score = 113 bits (272), Expect = 3e-24
Identities = 51/85 (60%), Positives = 69/85 (81%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN +++ +DPLY+GL Q RV G YDE+++EF+ AV ++ + ++QFEDF N NAFRL
Sbjct: 200 GTNNEALRNDPLYVGLPQPRVTGEIYDEMIEEFVLAVQEQFPR-AMIQFEDFSNDNAFRL 258
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAG 509
LEKY+++ CTFNDDIQGTAAVA+AG
Sbjct: 259 LEKYQDRICTFNDDIQGTAAVALAG 283
>UniRef50_A7CWP9 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=1;
Opitutaceae bacterium TAV2|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Opitutaceae
bacterium TAV2
Length = 561
Score = 126 bits (304), Expect = 5e-28
Identities = 55/83 (66%), Positives = 68/83 (81%)
Frame = +1
Query: 4 KFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPV 183
++G +RRPRGLFI+I D+G + ++L++WP TDVR IVVTDGERILGLGDLG GMGIPV
Sbjct: 121 EYGANFRRPRGLFISIKDRGRIAEILRHWPITDVRMIVVTDGERILGLGDLGVLGMGIPV 180
Query: 184 GKLALYTALGGIKPHQCLPITID 252
GKLALY+A G+ P CLPI +D
Sbjct: 181 GKLALYSACAGLHPSYCLPIALD 203
Score = 101 bits (242), Expect = 1e-20
Identities = 46/85 (54%), Positives = 65/85 (76%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
G + +++ +DPLY+G +RVRG DYD L+EF+ AV + + ++Q+EDFGN NAFRL
Sbjct: 205 GIDNETLRNDPLYLGHPMKRVRGADYDAFLNEFVEAVKTVFPKT-MIQWEDFGNTNAFRL 263
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAG 509
L + R++ C+FNDDIQGTAAVA+AG
Sbjct: 264 LHENRSRVCSFNDDIQGTAAVALAG 288
>UniRef50_Q89G76 Cluster: Malic enzyme; n=3; cellular organisms|Rep:
Malic enzyme - Bradyrhizobium japonicum
Length = 531
Score = 125 bits (301), Expect = 1e-27
Identities = 55/85 (64%), Positives = 69/85 (81%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIP 180
QK+GL+++RPRG+FI+ D+G + ++LKNWP R IVVTDGERILGLGDLGA GMGIP
Sbjct: 96 QKYGLIFQRPRGMFISSRDRGQIAEILKNWPYP-ARLIVVTDGERILGLGDLGANGMGIP 154
Query: 181 VGKLALYTALGGIKPHQCLPITIDV 255
VGKL+LY+A G+ P CLPI +DV
Sbjct: 155 VGKLSLYSACAGVHPEHCLPIVLDV 179
Score = 108 bits (260), Expect = 1e-22
Identities = 50/85 (58%), Positives = 64/85 (75%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN + +L+DP Y+GLR+RR+ G YD +DEFM A R+ L+QFEDF N +AF+L
Sbjct: 180 GTNNEELLNDPYYLGLRERRLTGEAYDSFVDEFMVAA-RKTFPGVLIQFEDFANHSAFKL 238
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAG 509
L KYR++ C FNDDIQGTAAVA+AG
Sbjct: 239 LHKYRDEACVFNDDIQGTAAVALAG 263
>UniRef50_A7PC00 Cluster: Chromosome chr2 scaffold_11, whole genome
shotgun sequence; n=3; Vitis vinifera|Rep: Chromosome
chr2 scaffold_11, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 573
Score = 122 bits (295), Expect = 6e-27
Identities = 54/85 (63%), Positives = 67/85 (78%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIP 180
QK+G ++RRP+ L+I G + +VLKNWPE ++ IVVT+GERILGLGDLG GMGIP
Sbjct: 293 QKYGSIFRRPQSLYIIDFFMGKILEVLKNWPERSIQVIVVTNGERILGLGDLGCQGMGIP 352
Query: 181 VGKLALYTALGGIKPHQCLPITIDV 255
VGKL+LYT LGG+ P CLP+TIDV
Sbjct: 353 VGKLSLYTTLGGLHPSVCLPVTIDV 377
Score = 42.7 bits (96), Expect = 0.007
Identities = 18/34 (52%), Positives = 23/34 (67%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFM 356
GTN + +L D YIGL+QRR G +Y ELL E +
Sbjct: 378 GTNNEQLLKDEFYIGLKQRRATGQEYAELLHELI 411
>UniRef50_Q0AIF8 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=2;
Nitrosomonas|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Nitrosomonas
eutropha (strain C71)
Length = 536
Score = 120 bits (290), Expect = 2e-26
Identities = 51/84 (60%), Positives = 66/84 (78%)
Frame = +1
Query: 4 KFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPV 183
K ++R+P+G +IT D+G + LKNWPETDV+ IVVTDGERILGLGDLGA GMGIP+
Sbjct: 103 KLSHIFRKPQGFYITPEDRGEIISRLKNWPETDVQIIVVTDGERILGLGDLGANGMGIPI 162
Query: 184 GKLALYTALGGIKPHQCLPITIDV 255
GK++LY A GI P +C+P+ +DV
Sbjct: 163 GKISLYVACAGIYPDRCMPVMLDV 186
Score = 93.5 bits (222), Expect = 4e-18
Identities = 47/95 (49%), Positives = 63/95 (66%), Gaps = 1/95 (1%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GT Q++ +DPLY+G R+ G DY L+DEF+ AV RY + L+QFEDF + NAF L
Sbjct: 187 GTGNQALREDPLYLGYPYPRLVGQDYLSLVDEFVEAVQHRY-PDALIQFEDFSSRNAFTL 245
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAG-YSPVSDSHR 536
L++Y FNDDIQGTAAV +AG Y+ +H+
Sbjct: 246 LDRYAASVRCFNDDIQGTAAVTLAGIYASCRITHK 280
>UniRef50_A1ZAF7 Cluster: Malic enzyme; n=5; Sophophora|Rep: Malic
enzyme - Drosophila melanogaster (Fruit fly)
Length = 603
Score = 116 bits (278), Expect = 6e-25
Identities = 48/86 (55%), Positives = 63/86 (73%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GT+ Q++L DPLY+G R RV+GP+YDEL+DEFM + V+ +G N + FEDF NA +
Sbjct: 219 GTDNQALLQDPLYVGARIPRVKGPEYDELVDEFMESAVKCFGNNTFIHFEDFATPNALKF 278
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAGY 512
LEKY+ KYC FNDDIQGT A +A +
Sbjct: 279 LEKYQYKYCCFNDDIQGTGATGLAAF 304
Score = 104 bits (249), Expect = 2e-21
Identities = 45/83 (54%), Positives = 62/83 (74%)
Frame = +1
Query: 7 FGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVG 186
+GL +++ LFI+IHDKGH+ D++ NW + V+AI VTDG R+LGLGD+GA MGI +G
Sbjct: 136 YGLNFQQAISLFISIHDKGHIRDLMHNWVDEGVKAICVTDGGRVLGLGDMGANAMGISLG 195
Query: 187 KLALYTALGGIKPHQCLPITIDV 255
K+ LYTALG I P +P+ +DV
Sbjct: 196 KMILYTALGSIPPSTLMPVCLDV 218
>UniRef50_A4RZU1 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus lucimarinus CCE9901
Length = 539
Score = 113 bits (271), Expect = 5e-24
Identities = 54/84 (64%), Positives = 64/84 (76%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN Q +LDDP Y GLR+ R++G YD L+DEFMR + R + CLVQFEDFGNANAFR+
Sbjct: 175 GTNNQRLLDDPNYKGLRRTRLKGEAYDALVDEFMREM-RAWQPRCLVQFEDFGNANAFRI 233
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVA 506
LEKYR FNDDIQGTAA+ +A
Sbjct: 234 LEKYRTTGPCFNDDIQGTAAITLA 257
Score = 73.7 bits (173), Expect = 3e-12
Identities = 33/51 (64%), Positives = 38/51 (74%)
Frame = +1
Query: 103 VRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDV 255
V VVTDGERILGLGDLGA GMGI GK+ LYT G++P CLP+ +DV
Sbjct: 124 VAVAVVTDGERILGLGDLGAGGMGISEGKILLYTVCAGVRPSACLPVCLDV 174
>UniRef50_A7IMB8 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=2;
Alphaproteobacteria|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Xanthobacter
sp. (strain Py2)
Length = 550
Score = 111 bits (266), Expect = 2e-23
Identities = 47/85 (55%), Positives = 63/85 (74%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIP 180
+ FG +YRRPRG++IT H KG + +VL+NWP+ D+R + V+ G RILGLGD+GA GMGIP
Sbjct: 115 EAFGNLYRRPRGMYITRHMKGRMAEVLRNWPQKDIRFVCVSTGGRILGLGDIGANGMGIP 174
Query: 181 VGKLALYTALGGIKPHQCLPITIDV 255
+GKL LYTA + P LP+ D+
Sbjct: 175 IGKLQLYTACAAVPPDVLLPVLFDI 199
Score = 80.6 bits (190), Expect = 3e-14
Identities = 37/85 (43%), Positives = 57/85 (67%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GT+ + + DP Y+G R+ V + DEL +EF++AV + C V FED+ +A R+
Sbjct: 200 GTSNEHLRADPFYLGTREAPVSEAELDELTEEFVQAVNEVF-PGCCVHFEDWKGTDAIRM 258
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAG 509
L++Y++K +NDDIQGTA+VA+AG
Sbjct: 259 LDRYKDKILCYNDDIQGTASVALAG 283
>UniRef50_Q8I8I4 Cluster: Malic enzyme; n=4; Eukaryota|Rep: Malic
enzyme - Mastigamoeba balamuthi (Phreatamoeba balamuthi)
Length = 568
Score = 110 bits (264), Expect = 3e-23
Identities = 51/84 (60%), Positives = 62/84 (73%)
Frame = +1
Query: 4 KFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPV 183
KF +R P GL+IT DKGHV ++L+NWP +V IVVTDG RILGLGDLG+ GMGIP+
Sbjct: 132 KFSAEFRNPTGLYITPEDKGHVAEILENWPH-EVEIIVVTDGGRILGLGDLGSNGMGIPI 190
Query: 184 GKLALYTALGGIKPHQCLPITIDV 255
GKL LY A G +P + LP+ IDV
Sbjct: 191 GKLHLYIACAGFRPDRTLPVMIDV 214
Score = 92.7 bits (220), Expect = 7e-18
Identities = 44/85 (51%), Positives = 60/85 (70%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN Q +LDDP+Y+G+R+ R+ +Y LL+EFM AV ++ + CLVQFEDF N F+L
Sbjct: 215 GTNRQELLDDPMYLGVRKARLGDAEYFALLEEFMTAVRAKWPR-CLVQFEDFPNPRCFQL 273
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAG 509
L+ + + FNDDIQGT AV +AG
Sbjct: 274 LDTWFGRQFCFNDDIQGTGAVILAG 298
>UniRef50_A6SA55 Cluster: Malic enzyme; n=2; Sclerotiniaceae|Rep:
Malic enzyme - Botryotinia fuckeliana B05.10
Length = 685
Score = 110 bits (264), Expect = 3e-23
Identities = 47/80 (58%), Positives = 63/80 (78%)
Frame = +1
Query: 16 VYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLA 195
+Y++P GL+++ HD+G++ +VL NW ++DV VVTDG RILGLGDLG GMGIPVGKL+
Sbjct: 191 IYQQPEGLYLSYHDRGNLEEVLGNWRQSDVEMTVVTDGSRILGLGDLGVNGMGIPVGKLS 250
Query: 196 LYTALGGIKPHQCLPITIDV 255
LYT GI P + LPIT+D+
Sbjct: 251 LYTGCAGIHPSKTLPITLDL 270
Score = 79.0 bits (186), Expect = 9e-14
Identities = 44/98 (44%), Positives = 59/98 (60%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN + L DPLY+G R +RV + E ++E M A+ + + +VQ+EDF N F
Sbjct: 271 GTNNEKFLKDPLYMGNRMKRVSTKEEAEFMEELMVALNKMW-PGIIVQYEDF--KNPFPS 327
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAGYSPVSDSHRRGCP 548
L KY+NKY FNDDIQGT AV +AG ++ R G P
Sbjct: 328 LAKYQNKYPCFNDDIQGTGAVILAGI--INALRRTGVP 363
>UniRef50_Q016K2 Cluster: NADP dependent malic enzyme; n=2;
Ostreococcus|Rep: NADP dependent malic enzyme -
Ostreococcus tauri
Length = 641
Score = 109 bits (263), Expect = 4e-23
Identities = 47/82 (57%), Positives = 64/82 (78%)
Frame = +1
Query: 10 GLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGK 189
GL+YR+PRGL++++ DKG VY +LKNWP +V+A+V+TDG+R+ G+GDLG GM V K
Sbjct: 182 GLMYRQPRGLYVSMQDKGSVYRLLKNWPVRNVKAVVLTDGQRVTGIGDLGVQGMPAAVSK 241
Query: 190 LALYTALGGIKPHQCLPITIDV 255
+L+TALGG+ P LPI IDV
Sbjct: 242 ASLFTALGGLDPADVLPICIDV 263
Score = 91.1 bits (216), Expect = 2e-17
Identities = 41/84 (48%), Positives = 58/84 (69%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GT+ Q++L+D YIGLRQ+RV G Y+ELLDE + + RR+G L+ FE+F NANA +L
Sbjct: 264 GTDNQTLLEDKFYIGLRQKRVGGEAYEELLDEVVSGLKRRFGPRVLLCFEEFSNANAKKL 323
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVA 506
L +Y + DD+QG AA+ +A
Sbjct: 324 LSRYNRDSVAYVDDLQGVAAITLA 347
>UniRef50_Q86NT5 Cluster: Malic enzyme; n=2; Drosophila
melanogaster|Rep: Malic enzyme - Drosophila melanogaster
(Fruit fly)
Length = 610
Score = 109 bits (262), Expect = 6e-23
Identities = 51/84 (60%), Positives = 62/84 (73%), Gaps = 1/84 (1%)
Frame = +1
Query: 7 FGLVYRRPRGLFITIHDKGHVYDVLKNWP-ETDVRAIVVTDGERILGLGDLGACGMGIPV 183
+G++YR G+ IT HD+GH+ +L NWP V+AI VTDG+RILGLGDLGA GMGI V
Sbjct: 144 YGMLYRGMTGIHITKHDRGHMKQILSNWPMRRSVKAICVTDGQRILGLGDLGANGMGIAV 203
Query: 184 GKLALYTALGGIKPHQCLPITIDV 255
GK+ LYTAL GI P LPI +DV
Sbjct: 204 GKMELYTALAGIPPSMLLPICLDV 227
Score = 106 bits (255), Expect = 4e-22
Identities = 47/85 (55%), Positives = 60/85 (70%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN +S+ +DPLYIGLR R++G +Y +DEFM AVV +G L+ FEDF NAF
Sbjct: 228 GTNNKSLHEDPLYIGLRDERLKGDEYVCFVDEFMEAVVSTFGDQTLIHFEDFATPNAFMF 287
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAG 509
L +Y++ YC FNDDIQGTAAV + G
Sbjct: 288 LNRYQHCYCHFNDDIQGTAAVGLGG 312
>UniRef50_Q4X1Z2 Cluster: NADP-dependent malic enzyme MaeA; n=11;
Pezizomycotina|Rep: NADP-dependent malic enzyme MaeA -
Aspergillus fumigatus (Sartorya fumigata)
Length = 661
Score = 107 bits (256), Expect = 3e-22
Identities = 44/85 (51%), Positives = 64/85 (75%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIP 180
QK+ +Y++P G++++ D+G++ V+ NWP+ +V +TDG RILGLGDLG GMGIP
Sbjct: 178 QKWSEIYQQPEGMYLSWEDRGNLAAVIANWPQPNVEITCITDGSRILGLGDLGINGMGIP 237
Query: 181 VGKLALYTALGGIKPHQCLPITIDV 255
+GKLALYTA GI+P LP+T+D+
Sbjct: 238 IGKLALYTACAGIRPEATLPLTLDL 262
Score = 77.8 bits (183), Expect = 2e-13
Identities = 40/98 (40%), Positives = 60/98 (61%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GT+ +++ +DPLY+G R+ ++ + E +DE M A+ R+ ++QFEDF N F
Sbjct: 263 GTSNKALREDPLYMGTRRDKISPEEEREFMDELMAALTERW-PGIVIQFEDF--KNPFPA 319
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAGYSPVSDSHRRGCP 548
LE+YR+ Y FNDDIQGT AV + G ++ R G P
Sbjct: 320 LERYRDAYTCFNDDIQGTGAVILGGV--INAVKRSGLP 355
>UniRef50_Q5BX10 Cluster: Malic enzyme; n=1; Schistosoma
japonicum|Rep: Malic enzyme - Schistosoma japonicum
(Blood fluke)
Length = 216
Score = 105 bits (251), Expect = 1e-21
Identities = 44/62 (70%), Positives = 55/62 (88%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIP 180
Q++G+V+RRPRGL+ITIHD+ H+ ++L NWPE V+AIV TDGERILGLGDLGA GMGIP
Sbjct: 150 QRYGVVFRRPRGLYITIHDRHHIPEILNNWPEPIVKAIVFTDGERILGLGDLGAYGMGIP 209
Query: 181 VG 186
+G
Sbjct: 210 IG 211
>UniRef50_Q8D911 Cluster: NAD-dependent malic enzyme; n=187;
cellular organisms|Rep: NAD-dependent malic enzyme -
Vibrio vulnificus
Length = 562
Score = 104 bits (249), Expect = 2e-21
Identities = 50/92 (54%), Positives = 63/92 (68%), Gaps = 1/92 (1%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIP 180
+ F +YRR RGLF++ ++ + D+L N +V+ IVVTDGERILGLGD G GMGIP
Sbjct: 110 ENFSNIYRRGRGLFVSYANRDRIDDILNNASNHNVKVIVVTDGERILGLGDQGIGGMGIP 169
Query: 181 VGKLALYTALGGIKPHQCLPITIDV-VRTPSR 273
+GKL+LYTA GGI P LPI +DV P R
Sbjct: 170 IGKLSLYTACGGISPAYTLPIVLDVGTNNPQR 201
Score = 101 bits (241), Expect = 2e-20
Identities = 46/83 (55%), Positives = 59/83 (71%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN L DP+Y+G R R+ G DYD ++EF++AV RR+ + L+QFEDF NA L
Sbjct: 195 GTNNPQRLADPMYMGWRHPRITGADYDAFVEEFIQAVQRRW-PDALIQFEDFAQKNAMPL 253
Query: 435 LEKYRNKYCTFNDDIQGTAAVAV 503
LE+Y+N+ C FNDDIQGTAAV V
Sbjct: 254 LERYKNRICCFNDDIQGTAAVTV 276
>UniRef50_Q01AM5 Cluster: NADP+-dependent malic enzyme; n=2;
Ostreococcus|Rep: NADP+-dependent malic enzyme -
Ostreococcus tauri
Length = 580
Score = 103 bits (246), Expect = 5e-21
Identities = 49/87 (56%), Positives = 64/87 (73%), Gaps = 2/87 (2%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN Q++LDDPLYIGL+Q+R R YD LLDE + AV RYGQ ++ +EDF NAFR+
Sbjct: 226 GTNNQTLLDDPLYIGLKQKRDRTKAYDALLDEIVVAVRSRYGQKTIIHWEDFAPKNAFRV 285
Query: 435 LEKYRN--KYCTFNDDIQGTAAVAVAG 509
L +++ + T+NDDIQGTAAV V+G
Sbjct: 286 LRRFQQAPEVVTYNDDIQGTAAVTVSG 312
Score = 97.1 bits (231), Expect = 3e-19
Identities = 44/83 (53%), Positives = 59/83 (71%)
Frame = +1
Query: 4 KFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPV 183
KFG + +RP GL+++ +D G+V +++NWP TDV+ V+TDGERILGLGD GA GMGI
Sbjct: 143 KFGTLVQRPMGLWVSSNDAGNVKQLIRNWPATDVKIAVITDGERILGLGDQGANGMGISA 202
Query: 184 GKLALYTALGGIKPHQCLPITID 252
GK +Y A G+ P LPI +D
Sbjct: 203 GKSMVYAAC-GVPPSALLPIQVD 224
>UniRef50_A2EKE3 Cluster: Malic enzyme; n=14; Trichomonadidae|Rep:
Malic enzyme - Trichomonas vaginalis G3
Length = 567
Score = 103 bits (246), Expect = 5e-21
Identities = 46/85 (54%), Positives = 61/85 (71%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIP 180
QK+ + RG++IT D G + D+L+N+P D+R IVVTD RILGLGDLGA G+GIP
Sbjct: 121 QKWATHRQSYRGIYITPEDSGKIKDILRNYPRQDIRCIVVTDAGRILGLGDLGASGLGIP 180
Query: 181 VGKLALYTALGGIKPHQCLPITIDV 255
VGKL LYT +G + P Q LP+ +D+
Sbjct: 181 VGKLMLYTLIGQVDPDQTLPVQLDM 205
Score = 92.3 bits (219), Expect = 9e-18
Identities = 54/136 (39%), Positives = 71/136 (52%)
Frame = +3
Query: 141 GSGRLGRMRDGHPCGQTXXXXXXXXXXXXSVSAHHYRRGTNTQSMLDDPLYIGLRQRRVR 320
G G LG G P G+ GT+ + +L DPLY G R RVR
Sbjct: 168 GLGDLGASGLGIPVGKLMLYTLIGQVDPDQTLPVQLDMGTDRKEILADPLYHGWRHPRVR 227
Query: 321 GPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRLLEKYRNKYCTFNDDIQGTAAVA 500
G ++ + + EF+ AV +G CLVQFEDF AF+LL+ +R + FNDDI+GTAAVA
Sbjct: 228 GAEHLKFVTEFVEAVKEVFGDTCLVQFEDFEMETAFKLLDHFRWRCNCFNDDIEGTAAVA 287
Query: 501 VAGYSPVSDSHRRGCP 548
A + S +H G P
Sbjct: 288 AA--TLASATHMEGVP 301
>UniRef50_Q875H8 Cluster: Malic enzyme; n=1; Mucor
circinelloides|Rep: Malic enzyme - Mucor circinelloides
Length = 617
Score = 102 bits (245), Expect = 6e-21
Identities = 44/80 (55%), Positives = 58/80 (72%)
Frame = +1
Query: 16 VYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLA 195
+YRR RG++ + D+G + ++ NWP V IVVTDG R+LGLGDLGA GM IP+GKL+
Sbjct: 151 IYRRSRGMYFSSQDRGQMSAMVYNWPHDKVDVIVVTDGSRVLGLGDLGANGMEIPIGKLS 210
Query: 196 LYTALGGIKPHQCLPITIDV 255
LY A GGI+P LP+ +DV
Sbjct: 211 LYVAAGGIRPRAVLPVVLDV 230
Score = 89.8 bits (213), Expect = 5e-17
Identities = 39/85 (45%), Positives = 59/85 (69%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN Q +L+DPLY+G+ R+ G +Y +DE++ A+ R+ + L+QFEDF +A+ L
Sbjct: 231 GTNNQDLLNDPLYLGMSHPRLEGEEYYSFIDEWVTAITSRW-PDTLIQFEDFKYPHAYNL 289
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAG 509
L KYRN+ FNDDIQ T+++ +AG
Sbjct: 290 LAKYRNRITCFNDDIQSTSSITLAG 314
>UniRef50_P37221 Cluster: NAD-dependent malic enzyme 62 kDa isoform,
mitochondrial precursor; n=41; Eukaryota|Rep:
NAD-dependent malic enzyme 62 kDa isoform, mitochondrial
precursor - Solanum tuberosum (Potato)
Length = 626
Score = 102 bits (245), Expect = 6e-21
Identities = 47/85 (55%), Positives = 65/85 (76%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GT+ +++L DPLY+GL+ R+ G +Y E++DEFM AV R+ + +VQFEDF + AF+L
Sbjct: 240 GTDNENLLKDPLYLGLQDHRLDGEEYIEVIDEFMEAVFTRW-PHVIVQFEDFQSKWAFKL 298
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAG 509
L++YRN Y FNDDIQGTA VA+AG
Sbjct: 299 LQRYRNNYRMFNDDIQGTAGVAIAG 323
Score = 101 bits (243), Expect = 1e-20
Identities = 45/85 (52%), Positives = 59/85 (69%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIP 180
QK+ ++RRPRG++ + D+G + ++ NWP V IVVTDG RILGLGDLG G+GI
Sbjct: 155 QKYSGLFRRPRGMYFSAEDRGEMMSMVYNWPADQVDMIVVTDGSRILGLGDLGIQGIGIA 214
Query: 181 VGKLALYTALGGIKPHQCLPITIDV 255
+GKL LY A GI P + LP+ IDV
Sbjct: 215 IGKLDLYVAAAGINPQRVLPVMIDV 239
>UniRef50_P78715 Cluster: Malic enzyme, hydrogenosomal precursor;
n=1; Neocallimastix frontalis|Rep: Malic enzyme,
hydrogenosomal precursor - Neocallimastix frontalis
(Rumen fungus)
Length = 592
Score = 101 bits (242), Expect = 1e-20
Identities = 47/85 (55%), Positives = 57/85 (67%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIP 180
QKF ++ + RG++ + D+G + V NWP DV IVVTDG RILGLGDLGA GM IP
Sbjct: 143 QKFHKIFTQTRGMYFSTADRGQMSAVAANWPYDDVDVIVVTDGSRILGLGDLGAGGMQIP 202
Query: 181 VGKLALYTALGGIKPHQCLPITIDV 255
+GKL LY GGI P LPI +DV
Sbjct: 203 IGKLTLYVCGGGINPRNVLPIVLDV 227
Score = 84.2 bits (199), Expect = 2e-15
Identities = 36/84 (42%), Positives = 59/84 (70%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN + +L+DPLY+G++ R++G ++ +DE++ A+ R+ + ++QFEDF NA L
Sbjct: 228 GTNNKELLNDPLYLGMQHPRLQGEEFHAFVDEWVSAITDRFPK-AVIQFEDFMMPNALDL 286
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVA 506
L KY+++ C FNDDIQ T A+ +A
Sbjct: 287 LLKYKDQICMFNDDIQSTGAITLA 310
>UniRef50_Q4PC56 Cluster: Malic enzyme; n=1; Ustilago maydis|Rep:
Malic enzyme - Ustilago maydis (Smut fungus)
Length = 634
Score = 101 bits (241), Expect = 2e-20
Identities = 46/87 (52%), Positives = 62/87 (71%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN + L+DPLY+GLR+ R +Y E +DE M A+ RY N ++QFEDF + NAFR
Sbjct: 260 GTNNKKNLEDPLYLGLRRERASTEEYIEFMDEVMHALHTRY-PNLIIQFEDFTSENAFRF 318
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAGYS 515
LE+Y+ KY FNDDIQGT +V +AG++
Sbjct: 319 LERYQGKYPMFNDDIQGTGSVILAGFT 345
Score = 97.9 bits (233), Expect = 2e-19
Identities = 46/87 (52%), Positives = 58/87 (66%), Gaps = 2/87 (2%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPET--DVRAIVVTDGERILGLGDLGACGMG 174
QKF +YRRP GL I++ DKG + +++NWP R V+TDG RILGLGDLG G G
Sbjct: 173 QKFSHIYRRPEGLSISLEDKGKIASIVENWPVPAGSPRIAVITDGSRILGLGDLGWNGQG 232
Query: 175 IPVGKLALYTALGGIKPHQCLPITIDV 255
I +GKL+LY A GI P LPI +D+
Sbjct: 233 ISIGKLSLYVAGAGIHPRATLPIVVDL 259
>UniRef50_A3BK03 Cluster: Malic enzyme; n=2; Oryza sativa|Rep: Malic
enzyme - Oryza sativa subsp. japonica (Rice)
Length = 635
Score = 100 bits (239), Expect = 3e-20
Identities = 44/85 (51%), Positives = 58/85 (68%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIP 180
Q + ++RRPRG++ + D+G + ++ NWP V IVVTDG RILGLGDLG G+GI
Sbjct: 189 QNYSGLFRRPRGMYFSAEDRGEMMSMVYNWPADQVDMIVVTDGSRILGLGDLGVHGIGIA 248
Query: 181 VGKLALYTALGGIKPHQCLPITIDV 255
+GKL LY A GI P + LP+ IDV
Sbjct: 249 IGKLDLYVAAAGINPQRVLPVMIDV 273
Score = 90.6 bits (215), Expect = 3e-17
Identities = 46/97 (47%), Positives = 64/97 (65%), Gaps = 3/97 (3%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN + +L DPLY+GL++ R+ G +Y ++DEFM AV R+ N +VQFEDF + AFRL
Sbjct: 274 GTNNEKLLKDPLYLGLQEHRLEGEEYVAIIDEFMEAVFARW-PNVIVQFEDFQSKWAFRL 332
Query: 435 LEKYRNKYCTFNDDIQGTA---AVAVAGYSPVSDSHR 536
L++YR Y FNDD+Q A A+ AG V+ + R
Sbjct: 333 LQRYRKTYRMFNDDVQINALSLALTSAGIGVVNAASR 369
>UniRef50_A3QW96 Cluster: Malic enzyme; n=10; Tigriopus
californicus|Rep: Malic enzyme - Tigriopus californicus
(Marine copepod)
Length = 322
Score = 98.7 bits (235), Expect = 1e-19
Identities = 41/83 (49%), Positives = 58/83 (69%)
Frame = +1
Query: 7 FGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVG 186
F +YRRPRG++ + D+G + ++ NW +V A+V+TDG RILGLGDLG G+GI +G
Sbjct: 162 FSQLYRRPRGMYFSHGDRGEMASMVYNWESDEVDAVVITDGSRILGLGDLGLGGLGISIG 221
Query: 187 KLALYTALGGIKPHQCLPITIDV 255
KL LY A GG P + LP+ +D+
Sbjct: 222 KLDLYVAAGGFHPRRVLPVVLDI 244
Score = 85.4 bits (202), Expect = 1e-15
Identities = 39/79 (49%), Positives = 56/79 (70%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN Q +L+DP Y+GL+Q R+ G +Y ++DE M A R+ + L+Q EDF + +A L
Sbjct: 245 GTNNQKLLNDPNYLGLKQPRIDGEEYYAIMDELMAATKLRWPR-ALIQHEDFXSKHAVNL 303
Query: 435 LEKYRNKYCTFNDDIQGTA 491
L++YR++Y FNDDIQGTA
Sbjct: 304 LKRYRSEYLMFNDDIQGTA 322
>UniRef50_Q9HE50 Cluster: Malic enzyme; n=6; Pezizomycotina|Rep:
Malic enzyme - Neurospora crassa
Length = 1023
Score = 97.5 bits (232), Expect = 2e-19
Identities = 43/83 (51%), Positives = 56/83 (67%)
Frame = +1
Query: 4 KFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPV 183
++ +Y RP L+I+I + + +L+NWP VVTDG RILGLGDLG G+GIP+
Sbjct: 569 QYSTLYTRPEALYISIKQRKSIRTILRNWPYPQPEICVVTDGSRILGLGDLGVNGVGIPI 628
Query: 184 GKLALYTALGGIKPHQCLPITID 252
GKLALYTA GI P + LPI +D
Sbjct: 629 GKLALYTAAAGIHPDKTLPIVLD 651
Score = 92.7 bits (220), Expect = 7e-18
Identities = 43/86 (50%), Positives = 59/86 (68%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GT ++ L DPLY+GLRQ+R+ + E +DEFM A + + +VQFEDF + AF
Sbjct: 653 GTANETNLKDPLYLGLRQKRIPVAEQQEFMDEFMEAAAEVF-PDMVVQFEDFESEKAFNY 711
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAGY 512
L++YR++Y FNDDIQGT AV +AGY
Sbjct: 712 LDRYRDQYKCFNDDIQGTGAVVLAGY 737
>UniRef50_UPI0000D9F768 Cluster: PREDICTED: similar to Y48B6A.12,
partial; n=1; Macaca mulatta|Rep: PREDICTED: similar to
Y48B6A.12, partial - Macaca mulatta
Length = 456
Score = 96.3 bits (229), Expect = 6e-19
Identities = 44/85 (51%), Positives = 59/85 (69%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIP 180
Q FG ++R RGL+ + +KG+ +++ N D IVVTDG RILGLGDLG GMGIP
Sbjct: 103 QLFGHIFRNARGLYFNLSEKGNFKEMVWNSNVRDADIIVVTDGSRILGLGDLGTNGMGIP 162
Query: 181 VGKLALYTALGGIKPHQCLPITIDV 255
+GKL+LY A GI P + +P+T+DV
Sbjct: 163 IGKLSLYVACAGINPGRTVPVTLDV 187
Score = 87.0 bits (206), Expect = 3e-16
Identities = 42/85 (49%), Positives = 58/85 (68%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN +L+D +Y+G R +RV G +Y +DEF+ AV R+ L+QFEDF N +AF L
Sbjct: 188 GTNNPDLLNDDMYLGERHKRVDGEEYYAAVDEFVDAVRSRW-PGVLIQFEDFTNDHAFPL 246
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAG 509
L++Y+ FNDDIQGT +VA+AG
Sbjct: 247 LKRYQENILCFNDDIQGTGSVALAG 271
>UniRef50_Q4QAQ6 Cluster: Malic enzyme, putative; n=20;
Trypanosomatidae|Rep: Malic enzyme, putative -
Leishmania major
Length = 573
Score = 95.5 bits (227), Expect = 1e-18
Identities = 40/85 (47%), Positives = 63/85 (74%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIP 180
Q++G +Y++ GL++ + KG V +++N +T++ IV+TDG RILGLGDLG+ G+GI
Sbjct: 115 QRYGDLYQKDHGLYLDVASKGKVRRLIQNLRKTNIDVIVITDGSRILGLGDLGSNGIGIS 174
Query: 181 VGKLALYTALGGIKPHQCLPITIDV 255
+GK +LY A GG+KP + LP+ +DV
Sbjct: 175 IGKCSLYVAAGGVKPSRVLPVVMDV 199
Score = 90.6 bits (215), Expect = 3e-17
Identities = 44/86 (51%), Positives = 58/86 (67%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN + ++PLY+GLR+ R D+ LLDEFM AV + + +VQFEDF N + F +
Sbjct: 200 GTNNLELRNNPLYLGLRKPRCGDADFYALLDEFMEAVKDTW-PSAVVQFEDFSNNHCFDM 258
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAGY 512
LE+Y+ KY FNDDIQGT AV AG+
Sbjct: 259 LERYQKKYRCFNDDIQGTGAVIAAGF 284
>UniRef50_Q5CS07 Cluster: Malic enzyme; n=2; Cryptosporidium|Rep:
Malic enzyme - Cryptosporidium parvum Iowa II
Length = 614
Score = 94.7 bits (225), Expect = 2e-18
Identities = 41/74 (55%), Positives = 56/74 (75%)
Frame = +1
Query: 34 GLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALG 213
GL++ KG +Y++LK++ D+ IV+TDG RILGLGDLG GMGIP+GKL+LY LG
Sbjct: 177 GLYLNKSHKGRIYEILKDFKSDDIEIIVLTDGGRILGLGDLGLNGMGIPMGKLSLYITLG 236
Query: 214 GIKPHQCLPITIDV 255
GI P + LPI++D+
Sbjct: 237 GIDPSKVLPISLDI 250
Score = 80.2 bits (189), Expect = 4e-14
Identities = 42/123 (34%), Positives = 67/123 (54%)
Frame = +3
Query: 141 GSGRLGRMRDGHPCGQTXXXXXXXXXXXXSVSAHHYRRGTNTQSMLDDPLYIGLRQRRVR 320
G G LG G P G+ V GTNT +L D Y+G+ ++R+
Sbjct: 213 GLGDLGLNGMGIPMGKLSLYITLGGIDPSKVLPISLDIGTNTNDILSDKYYLGICEKRID 272
Query: 321 GPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRLLEKYRNKYCTFNDDIQGTAAVA 500
+Y L+DE +A+ +R+ N ++Q+ED + A +L+ Y++K+ FNDDIQGTA++
Sbjct: 273 NDEYFPLMDEITKAIFKRW-PNTVLQWEDLTTSRAIDILDIYQDKFRCFNDDIQGTASIV 331
Query: 501 VAG 509
+AG
Sbjct: 332 LAG 334
>UniRef50_Q5K758 Cluster: Malic enzyme; n=1; Filobasidiella
neoformans|Rep: Malic enzyme - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 600
Score = 93.9 bits (223), Expect = 3e-18
Identities = 44/88 (50%), Positives = 58/88 (65%), Gaps = 3/88 (3%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDV---RAIVVTDGERILGLGDLGACGM 171
QK+ +Y P GL++ I DK + ++L + V + +VVTDG RILGLGDLG GM
Sbjct: 147 QKYSQIYSGPEGLYLNIEDKDRIPEILHQYASKLVAPPQILVVTDGSRILGLGDLGIGGM 206
Query: 172 GIPVGKLALYTALGGIKPHQCLPITIDV 255
GI VGKL LY A GG+ PH CLP+ +D+
Sbjct: 207 GISVGKLNLYVAGGGVNPHGCLPVVLDM 234
Score = 79.4 bits (187), Expect = 7e-14
Identities = 38/86 (44%), Positives = 56/86 (65%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN +++ +DPLYIGL+Q RV + E +D FM A + + ++Q EDF + AF
Sbjct: 235 GTNNEAVRNDPLYIGLKQPRVGLEEATEFMDAFMAAASEAFPK-AVIQHEDFYSEAAFDF 293
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAGY 512
L +Y+ KY FNDDI+GT +V +AG+
Sbjct: 294 LARYKEKYRMFNDDIEGTGSVILAGF 319
>UniRef50_Q00XN9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus tauri
Length = 639
Score = 93.1 bits (221), Expect = 5e-18
Identities = 41/85 (48%), Positives = 61/85 (71%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN + +L+DP Y+G+ ++R+ G +Y ++EF+R V R+ N L+QFEDF +A ++
Sbjct: 261 GTNNEDLLNDPYYLGVPRKRLEGEEYYAFIEEFIRGVRNRW-PNALIQFEDFQTKHANKI 319
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAG 509
L++YRN FNDDIQGTAAV +AG
Sbjct: 320 LQRYRNDVLCFNDDIQGTAAVVLAG 344
Score = 87.8 bits (208), Expect = 2e-16
Identities = 41/83 (49%), Positives = 54/83 (65%)
Frame = +1
Query: 7 FGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVG 186
F + RR RG++ ++ D+G + ++ NW + V IVVTDG RILGLGDLG GMGI G
Sbjct: 179 FSKLLRRARGMYFSVDDRGDINSMMFNWKRS-VSVIVVTDGSRILGLGDLGTNGMGISQG 237
Query: 187 KLALYTALGGIKPHQCLPITIDV 255
K+ LY A GG P LP+ +DV
Sbjct: 238 KVDLYVAGGGFDPQHVLPVVLDV 260
>UniRef50_Q5KEY3 Cluster: Malic enzyme; n=1; Filobasidiella
neoformans|Rep: Malic enzyme - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 629
Score = 91.1 bits (216), Expect = 2e-17
Identities = 42/84 (50%), Positives = 59/84 (70%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GT+ ++ DPLY+G ++ R+RG +YD+ +D F+ R N ++ FEDFG ANA+RL
Sbjct: 249 GTDNHALFSDPLYMGWKRTRIRGKNYDQFIDRFI-TNCRELFPNAIIHFEDFGMANAYRL 307
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVA 506
+EKY+N FNDDIQGT AVA+A
Sbjct: 308 MEKYKN-IPMFNDDIQGTGAVALA 330
Score = 58.4 bits (135), Expect = 1e-07
Identities = 35/98 (35%), Positives = 53/98 (54%), Gaps = 16/98 (16%)
Frame = +1
Query: 7 FGLVYRRPRGLFITIHDK--------GHVYDVLK--------NWPETDVRAIVVTDGERI 138
+ ++RRP G +I+ ++ GH+ DV + N P+ + +VVTD E I
Sbjct: 150 YSSLFRRPVGCYISFPNQDGMRAQLEGHLTDVNRTADVAYDSNKPDDAIDLVVVTDAEAI 209
Query: 139 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 252
LG+GD G G+ I K ALYT GI P++ LP+ +D
Sbjct: 210 LGIGDQGVGGITISTSKAALYTLGAGINPNRILPVVLD 247
>UniRef50_A0Q531 Cluster: NAD-dependent malic enzyme; n=10;
Francisella tularensis|Rep: NAD-dependent malic enzyme -
Francisella tularensis subsp. novicida (strain U112)
Length = 604
Score = 90.6 bits (215), Expect = 3e-17
Identities = 42/84 (50%), Positives = 57/84 (67%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN ++L+ P Y+G+R RV G YDE ++EF+ V R+ N + +ED G NA R+
Sbjct: 208 GTNNDALLNAPGYLGVRLPRVSGETYDEFIEEFVTQVKARF-PNVFLHWEDLGRDNATRI 266
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVA 506
LEKY++K CTFNDDI+GT VA A
Sbjct: 267 LEKYKDKLCTFNDDIEGTGIVATA 290
Score = 80.2 bits (189), Expect = 4e-14
Identities = 34/85 (40%), Positives = 54/85 (63%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIP 180
QK+ +R+ GLFI+I K H+ +L+ + + ++VTDGE +LG+GD G GM I
Sbjct: 123 QKYSSSFRKQSGLFISISHKKHIARILERYEYNSIDLVLVTDGEAVLGIGDQGIGGMNIS 182
Query: 181 VGKLALYTALGGIKPHQCLPITIDV 255
+GK+ +Y A GI P + LP+ +D+
Sbjct: 183 IGKIMVYVAASGIDPARVLPVQLDM 207
>UniRef50_Q4T5P0 Cluster: Malic enzyme; n=1; Tetraodon
nigroviridis|Rep: Malic enzyme - Tetraodon nigroviridis
(Green puffer)
Length = 306
Score = 88.2 bits (209), Expect = 1e-16
Identities = 38/46 (82%), Positives = 41/46 (89%)
Frame = +3
Query: 372 RYGQNCLVQFEDFGNANAFRLLEKYRNKYCTFNDDIQGTAAVAVAG 509
RYG +CL+QFEDF N NAFRLL KYR+ YCTFNDDIQGTAAVAVAG
Sbjct: 1 RYGMDCLIQFEDFANINAFRLLSKYRDMYCTFNDDIQGTAAVAVAG 46
>UniRef50_Q8Y5Y8 Cluster: Lmo1915 protein; n=15; Firmicutes|Rep:
Lmo1915 protein - Listeria monocytogenes
Length = 547
Score = 88.2 bits (209), Expect = 1e-16
Identities = 39/84 (46%), Positives = 58/84 (69%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN +++L+DPLY+G ++ R+ +YD + F+ V++ ++ +EDFG ANA R+
Sbjct: 190 GTNNETLLNDPLYLGNKRPRLSESEYDAFIASFVN-VMKEVFPKAILHWEDFGRANASRI 248
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVA 506
L YR+K CTFNDDIQGT A+ VA
Sbjct: 249 LHNYRDKICTFNDDIQGTGAMVVA 272
Score = 60.5 bits (140), Expect = 3e-08
Identities = 29/57 (50%), Positives = 38/57 (66%)
Frame = +1
Query: 82 KNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 252
KN P D+ IV+TDGE +LG+GD G+ I VGKLA+YT G+ P + LP+ ID
Sbjct: 134 KNNPNIDM--IVITDGEGVLGIGDWSVNGVKIAVGKLAVYTVAAGLAPDRVLPVVID 188
>UniRef50_Q7SHJ8 Cluster: Malic enzyme; n=12; Pezizomycotina|Rep:
Malic enzyme - Neurospora crassa
Length = 611
Score = 88.2 bits (209), Expect = 1e-16
Identities = 41/84 (48%), Positives = 56/84 (66%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN + +L D LY+GLRQ+R RG YD+ ++ F++A Y + + FEDFG NA RL
Sbjct: 217 GTNNEELLKDDLYLGLRQKRARGDKYDDFVETFIKAARELYPR-AYIHFEDFGLDNARRL 275
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVA 506
LE+YR + FNDD+QGT V +A
Sbjct: 276 LERYRPQMPCFNDDVQGTGCVTLA 299
Score = 79.0 bits (186), Expect = 9e-14
Identities = 40/86 (46%), Positives = 54/86 (62%), Gaps = 2/86 (2%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNW--PETDVRAIVVTDGERILGLGDLGACGMG 174
Q + ++RRP G+F+ I+D V L W PE D+ IVVTDGE ILG+GD G G+
Sbjct: 131 QNYSRLFRRPEGVFLNINDMDSVKRDLAQWGKPE-DIDYIVVTDGEEILGIGDQGCGGIL 189
Query: 175 IPVGKLALYTALGGIKPHQCLPITID 252
I + KL L T GGI P++ LP+ +D
Sbjct: 190 ISIAKLVLMTICGGIHPNRVLPVVLD 215
>UniRef50_A2QY66 Cluster: Malic enzyme; n=2; cellular organisms|Rep:
Malic enzyme - Aspergillus niger
Length = 609
Score = 88.2 bits (209), Expect = 1e-16
Identities = 39/84 (46%), Positives = 59/84 (70%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GT+ +S+L D LY+GLRQ RVRG +YD+ +++F+ +R+ + FEDFG NA R+
Sbjct: 239 GTDNESLLTDELYLGLRQSRVRGEEYDQFVEKFVETARKRF-PRAYIHFEDFGLHNAKRI 297
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVA 506
L+K++++ FNDDIQGT V +A
Sbjct: 298 LDKFKSRIPCFNDDIQGTGCVTLA 321
Score = 70.5 bits (165), Expect = 3e-11
Identities = 35/85 (41%), Positives = 51/85 (60%), Gaps = 1/85 (1%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPE-TDVRAIVVTDGERILGLGDLGACGMGI 177
Q + ++R+P G F+ I D+ + + L N+ +V IVV+DGE ILG+GD G + I
Sbjct: 153 QNYSRLFRKPEGCFLNIRDQDRIEECLSNFSRGEEVDYIVVSDGEEILGIGDQGVGAILI 212
Query: 178 PVGKLALYTALGGIKPHQCLPITID 252
V KLAL T GI P + LP+ +D
Sbjct: 213 SVAKLALTTLCAGIHPSRQLPVVLD 237
>UniRef50_P36013 Cluster: NAD-dependent malic enzyme, mitochondrial
precursor; n=15; Saccharomycetales|Rep: NAD-dependent
malic enzyme, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 669
Score = 87.4 bits (207), Expect = 3e-16
Identities = 42/84 (50%), Positives = 59/84 (70%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN + + D LY+G + R+RG YD+ L++F++AV + Y + ++ FEDFG NA RL
Sbjct: 282 GTNNKKLARDELYMGNKFSRIRGKQYDDFLEKFIKAVKKVY-PSAVLHFEDFGVKNARRL 340
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVA 506
LEKYR + +FNDDIQGT AV +A
Sbjct: 341 LEKYRYELPSFNDDIQGTGAVVMA 364
Score = 64.9 bits (151), Expect = 2e-09
Identities = 34/80 (42%), Positives = 49/80 (61%), Gaps = 1/80 (1%)
Frame = +1
Query: 19 YRRPRGLFITIHDKGHVYDVLKNWP-ETDVRAIVVTDGERILGLGDLGACGMGIPVGKLA 195
+R+P G+F+ I + + L + + DV IVV+D E ILG+GD G G+ I + KLA
Sbjct: 202 FRKPEGVFLDITEPDSIECRLATYGGDKDVDYIVVSDSEGILGIGDQGIGGVRIAISKLA 261
Query: 196 LYTALGGIKPHQCLPITIDV 255
L T GGI P + LP+ +DV
Sbjct: 262 LMTLCGGIHPGRVLPVCLDV 281
>UniRef50_P45868 Cluster: Probable NAD-dependent malic enzyme 2;
n=37; Bacteria|Rep: Probable NAD-dependent malic enzyme
2 - Bacillus subtilis
Length = 582
Score = 87.4 bits (207), Expect = 3e-16
Identities = 37/85 (43%), Positives = 60/85 (70%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN + +L+DPLYIG + RV+G Y+ +D +++A ++ + + L+ +ED GN NA +
Sbjct: 218 GTNNEKLLNDPLYIGNKHERVQGERYEAFIDAYVKAALKFFPK-ALLHWEDLGNKNARNI 276
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAG 509
++KY ++ TFNDDIQGT A+ +AG
Sbjct: 277 MKKYNHEILTFNDDIQGTGAITLAG 301
Score = 76.6 bits (180), Expect = 5e-13
Identities = 36/87 (41%), Positives = 55/87 (63%), Gaps = 2/87 (2%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPET--DVRAIVVTDGERILGLGDLGACGMG 174
Q++ YRRP+G++++I + + +N T D+ IV TD E ILG+GD G G+
Sbjct: 131 QEYSHEYRRPQGIYLSIDNIDGIEKAFENLHATAGDIDLIVATDSESILGIGDWGVGGIN 190
Query: 175 IPVGKLALYTALGGIKPHQCLPITIDV 255
I +GKLA+YTA GI P + +P+ +DV
Sbjct: 191 IAIGKLAVYTAAAGIDPSRVIPVVLDV 217
>UniRef50_A4SKB8 Cluster: NAD-dependent malic enzyme; n=2;
Aeromonas|Rep: NAD-dependent malic enzyme - Aeromonas
salmonicida (strain A449)
Length = 516
Score = 86.6 bits (205), Expect = 5e-16
Identities = 42/85 (49%), Positives = 59/85 (69%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIP 180
Q+ +Y R GL+++ HD+ + D + E +V IV++DGER+LGLGDLG GMGI
Sbjct: 91 QRHSDLYLRSHGLYLSWHDRDDL-DAIFAAVEQEVDVIVISDGERVLGLGDLGIGGMGIC 149
Query: 181 VGKLALYTALGGIKPHQCLPITIDV 255
+GKLALY+A GGI P + LP+ +DV
Sbjct: 150 IGKLALYSAAGGINPARTLPLCVDV 174
Score = 80.2 bits (189), Expect = 4e-14
Identities = 39/84 (46%), Positives = 54/84 (64%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN +L+D Y+G + RV G Y +D+ + A+ R+ Q ++QFEDF +A L
Sbjct: 175 GTNNPELLEDDSYLGWQANRVDGESYYHFMDKVVAAIRTRWPQ-VVLQFEDFAGKHAANL 233
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVA 506
L +YR++ C FNDDIQGTAAVA A
Sbjct: 234 LARYRDELCMFNDDIQGTAAVASA 257
>UniRef50_A4RQC9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus lucimarinus CCE9901
Length = 549
Score = 84.6 bits (200), Expect = 2e-15
Identities = 38/83 (45%), Positives = 53/83 (63%)
Frame = +1
Query: 7 FGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVG 186
F +YR G++ + D G + +L NWP + IVVTDG R+LGLGDLG GM I VG
Sbjct: 107 FDALYRNRCGMYFSRLDSGVMRRMLDNWPSPETEIIVVTDGGRVLGLGDLGTNGMAISVG 166
Query: 187 KLALYTALGGIKPHQCLPITIDV 255
K++LY A GG P + +P+ +D+
Sbjct: 167 KVSLYVASGGFDPAKSMPVCLDL 189
Score = 71.3 bits (167), Expect = 2e-11
Identities = 38/99 (38%), Positives = 58/99 (58%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GT+ ++ Y+G + R+ G + ++ EF AV ++ NCL+QFEDF +AFR+
Sbjct: 190 GTSNVALRAHDFYLGADEPRLTGDAHLAVVTEFCLAVKDKW-PNCLIQFEDFKTEDAFRI 248
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAGYSPVSDSHRRGCPT 551
L+ R+K FNDDIQGT A +AG ++ +G PT
Sbjct: 249 LDHMRHKVLCFNDDIQGTGATILAGL--INALRAQGTPT 285
>UniRef50_Q9RYN4 Cluster: Malate oxidoreductase; n=6;
Deinococci|Rep: Malate oxidoreductase - Deinococcus
radiodurans
Length = 580
Score = 83.8 bits (198), Expect = 3e-15
Identities = 40/85 (47%), Positives = 51/85 (60%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIP 180
+KF +YR PRGL ++ L N P DVR IV TD ILG+GD G GM I
Sbjct: 133 KKFSQIYRYPRGLTLSTRTIERAEQALANVPLNDVRIIVATDSSAILGIGDQGFGGMAIS 192
Query: 181 VGKLALYTALGGIKPHQCLPITIDV 255
+GKL+LYT GG+ P + LP+ +DV
Sbjct: 193 IGKLSLYTVAGGVGPDKTLPVELDV 217
Score = 79.8 bits (188), Expect = 5e-14
Identities = 35/85 (41%), Positives = 55/85 (64%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GT + +DP Y+G++ R+ G +Y +D+F+ A ++RY + ++Q+EDF AF +
Sbjct: 218 GTGRADLREDPHYLGVKHERLTGEEYFAFIDKFVEATIQRYPK-AIIQWEDFSKDAAFEV 276
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAG 509
L +YR +FNDDIQGT AV +AG
Sbjct: 277 LARYRKVVPSFNDDIQGTGAVVLAG 301
>UniRef50_A6XP71 Cluster: Malic enzyme protein 2; n=2;
Mucoromycotina|Rep: Malic enzyme protein 2 - Mortierella
alpina (Mortierella renispora)
Length = 669
Score = 82.6 bits (195), Expect = 7e-15
Identities = 41/83 (49%), Positives = 56/83 (67%), Gaps = 6/83 (7%)
Frame = +1
Query: 25 RPRGLFITIHDKGHVYDVLKNW------PETDVRAIVVTDGERILGLGDLGACGMGIPVG 186
+P GLF++I+D ++ +++N+ P + V+TDG RILGLGDLG GMGIPVG
Sbjct: 207 QPDGLFLSINDLPNLTQIIQNYKPFPQDPSLTPQIAVITDGSRILGLGDLGVGGMGIPVG 266
Query: 187 KLALYTALGGIKPHQCLPITIDV 255
KL LY A GI P + LPIT+D+
Sbjct: 267 KLQLYVAGAGIDPRRTLPITLDL 289
Score = 79.8 bits (188), Expect = 5e-14
Identities = 38/86 (44%), Positives = 55/86 (63%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN + L D Y+GLR++R + +D + A+ Y + L+QFEDF + +AF+L
Sbjct: 290 GTNNEDKLKDEFYLGLREKRAGDDKFFPFVDAVIEALTSLYPK-LLIQFEDFSSEHAFQL 348
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAGY 512
L+KY+ K FNDDIQGT AV +AG+
Sbjct: 349 LDKYQPKKFCFNDDIQGTGAVILAGF 374
>UniRef50_Q48796 Cluster: Malolactic enzyme; n=49; Bacteria|Rep:
Malolactic enzyme - Oenococcus oeni (Leuconostoc oenos)
Length = 541
Score = 82.6 bits (195), Expect = 7e-15
Identities = 37/85 (43%), Positives = 54/85 (63%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN + +L DP+Y+G + RVRG Y + +D+F+ + N + +EDFG +NA +
Sbjct: 187 GTNNEKLLKDPMYLGNKFNRVRGDKYYDFIDKFVNHAESLF-PNLYLHWEDFGRSNASNI 245
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAG 509
L Y++K TFNDDIQGT V +AG
Sbjct: 246 LNSYKDKIATFNDDIQGTGIVVLAG 270
Score = 61.3 bits (142), Expect = 2e-08
Identities = 32/86 (37%), Positives = 49/86 (56%), Gaps = 2/86 (2%)
Frame = +1
Query: 1 QKFGLVYRRPRGL-FITIHDKGHVYDVLKNWPE-TDVRAIVVTDGERILGLGDLGACGMG 174
+ + ++ P+G F+ I+ ++ LKN D++ +VV+D E ILG+GD G G+
Sbjct: 100 ENYSELFVEPQGAAFLDINHPENIQSTLKNAANGRDIKLLVVSDAEGILGIGDWGVQGVD 159
Query: 175 IPVGKLALYTALGGIKPHQCLPITID 252
I VGKL +YT GI P L + ID
Sbjct: 160 IAVGKLMVYTVAAGIDPSTVLAVVID 185
>UniRef50_P40375 Cluster: NAD-dependent malic enzyme; n=3;
Schizosaccharomyces pombe|Rep: NAD-dependent malic
enzyme - Schizosaccharomyces pombe (Fission yeast)
Length = 565
Score = 82.2 bits (194), Expect = 1e-14
Identities = 41/84 (48%), Positives = 53/84 (63%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN ++ + Y+GLR+ RVRG YD LD ++A+ R + FEDFG ANA R+
Sbjct: 200 GTNNETHRKNHQYMGLRKDRVRGEQYDSFLDNVIKAI-REVFPEAFIHFEDFGLANAKRI 258
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVA 506
L+ YR FNDDIQGT AVA+A
Sbjct: 259 LDHYRPDIACFNDDIQGTGAVALA 282
Score = 60.9 bits (141), Expect = 3e-08
Identities = 33/88 (37%), Positives = 52/88 (59%), Gaps = 3/88 (3%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITI--HDKGHVYDVLKNWPETD-VRAIVVTDGERILGLGDLGACGM 171
++F +YR P G ++ I +D ++ L + ++D V I++TD E ILG+GD G G+
Sbjct: 112 KQFSDIYRYPEGCYLDIDHNDLSYIKQQLSEFGKSDSVEYIIITDSEGILGIGDQGVGGV 171
Query: 172 GIPVGKLALYTALGGIKPHQCLPITIDV 255
I V K L T G+ P++ LPI +DV
Sbjct: 172 LISVAKGHLMTLCAGLDPNRFLPIVLDV 199
>UniRef50_A1SVL3 Cluster: Malic enzyme aka malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=4;
Gammaproteobacteria|Rep: Malic enzyme aka malate
dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)) -
Psychromonas ingrahamii (strain 37)
Length = 571
Score = 81.0 bits (191), Expect = 2e-14
Identities = 37/85 (43%), Positives = 55/85 (64%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIP 180
Q+F ++ RGL++T + V + + + D++ IVVTD + ILG+GD G GMGIP
Sbjct: 120 QEFSHRFQIARGLYLTTDNIHDVGSMAREFTGKDIQIIVVTDSQGILGIGDQGVGGMGIP 179
Query: 181 VGKLALYTALGGIKPHQCLPITIDV 255
+GKL+LYT GI P C+PI +D+
Sbjct: 180 IGKLSLYTLGAGIHPDHCMPIALDI 204
Score = 73.7 bits (173), Expect = 3e-12
Identities = 33/85 (38%), Positives = 54/85 (63%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GT+ Q +L DP+Y+G+ ++R+ G Y + F+ V + + ++Q+EDF +NAF
Sbjct: 205 GTDNQDLLADPMYLGIPKKRLTGEPYKAFIKTFVEQVKLHFPK-AVLQWEDFSKSNAFDN 263
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAG 509
L Y ++ +FNDD+QGT AV +AG
Sbjct: 264 LSDYEDELPSFNDDVQGTGAVVLAG 288
>UniRef50_Q6AL43 Cluster: Related to NAD-dependent malic enzyme;
n=1; Desulfotalea psychrophila|Rep: Related to
NAD-dependent malic enzyme - Desulfotalea psychrophila
Length = 578
Score = 78.6 bits (185), Expect = 1e-13
Identities = 36/81 (44%), Positives = 52/81 (64%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GT+ +++L D Y+G RQ+R+ G +Y +D F RA R N L Q+EDF NAF +
Sbjct: 206 GTDNEALLADKHYLGWRQKRLVGDEYTAFIDRFARAF-RNVFPNALCQWEDFSKQNAFDI 264
Query: 435 LEKYRNKYCTFNDDIQGTAAV 497
+KYR+ +FNDD+QGT A+
Sbjct: 265 RDKYRHSMVSFNDDVQGTGAI 285
Score = 77.8 bits (183), Expect = 2e-13
Identities = 36/85 (42%), Positives = 52/85 (61%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIP 180
QK+ ++R+ GL + D+L+ + D+R VVTD + ILG+GD GA G+ I
Sbjct: 121 QKYSAMFRQANGLHFSPDTIDQAEDILRRFAHRDIRVAVVTDNQGILGIGDQGAGGIAIC 180
Query: 181 VGKLALYTALGGIKPHQCLPITIDV 255
+GKL LYT GI P CLPI++D+
Sbjct: 181 LGKLMLYTQGAGIAPWHCLPISLDI 205
>UniRef50_Q7K3R0 Cluster: Malic enzyme; n=2; Sophophora|Rep: Malic
enzyme - Drosophila melanogaster (Fruit fly)
Length = 633
Score = 78.2 bits (184), Expect = 2e-13
Identities = 37/85 (43%), Positives = 54/85 (63%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN + +L+DP+Y GLR+RR YD+L +EF +V+++YG L+ +DF A +
Sbjct: 253 GTNNEELLNDPMYTGLRERRCSEKLYDQLFEEFTLSVMQQYGPRALILCKDFEAQKAKKQ 312
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAG 509
LE YR + C + D Q AAVA+AG
Sbjct: 313 LELYRERQCIVDVDFQCFAAVALAG 337
Score = 68.1 bits (159), Expect = 2e-10
Identities = 32/81 (39%), Positives = 46/81 (56%)
Frame = +1
Query: 13 LVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKL 192
+++ +GL+I I D GHV +L NWP VR ++V++G +L +GDLG M I L
Sbjct: 172 MIHSMGQGLYICIKDLGHVSQILSNWPFRCVRCLLVSNGASVLSVGDLGVDEMPILFSNL 231
Query: 193 ALYTALGGIKPHQCLPITIDV 255
GGI P CL + +DV
Sbjct: 232 HQNVVYGGIHPAYCLAVMLDV 252
>UniRef50_A3YYQ0 Cluster: Malate oxidoreductase; n=1; Synechococcus
sp. WH 5701|Rep: Malate oxidoreductase - Synechococcus
sp. WH 5701
Length = 517
Score = 76.6 bits (180), Expect = 5e-13
Identities = 42/98 (42%), Positives = 59/98 (60%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GT+ +L++PLY G R R+ G DYD L + A+ R++ L+ +EDFG +A +L
Sbjct: 150 GTDRVELLENPLYPGWRHPRLDGLDYDRFLARSVEALQRQF-PGALLHWEDFGTGHAHQL 208
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVAGYSPVSDSHRRGCP 548
LE+YR + +FNDDIQGT VA A + SH G P
Sbjct: 209 LERYRLQLPSFNDDIQGTRGVACAVVK--AASHGAGLP 244
Score = 67.3 bits (157), Expect = 3e-10
Identities = 35/86 (40%), Positives = 50/86 (58%), Gaps = 1/86 (1%)
Frame = +1
Query: 1 QKFGLVYRRPRG-LFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGI 177
Q+F L YR P G +F+ D + VL V I++TD + ILG+GD G G+ I
Sbjct: 64 QRFSLDYRTPSGGVFLAAPDLERIESVLSQAATGPVDLILITDSQGILGIGDQGIGGIEI 123
Query: 178 PVGKLALYTALGGIKPHQCLPITIDV 255
+GKLA+YT G+ P + LP+ +DV
Sbjct: 124 CLGKLAVYTLCAGLDPARVLPLVLDV 149
>UniRef50_A5C6I9 Cluster: Malic enzyme; n=1; Vitis vinifera|Rep:
Malic enzyme - Vitis vinifera (Grape)
Length = 498
Score = 74.5 bits (175), Expect = 2e-12
Identities = 35/71 (49%), Positives = 46/71 (64%)
Frame = +1
Query: 43 ITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIK 222
IT + H++ + + V IV+TDG RILGLGDLG G+GIP+GKL +Y A GI
Sbjct: 21 ITXNGIXHIWSDIGSXDLCQVDMIVITDGSRILGLGDLGVQGIGIPIGKLDMYVAAAGIN 80
Query: 223 PHQCLPITIDV 255
P + LPI +DV
Sbjct: 81 PQRILPIMLDV 91
Score = 68.1 bits (159), Expect = 2e-10
Identities = 53/151 (35%), Positives = 72/151 (47%), Gaps = 28/151 (18%)
Frame = +3
Query: 141 GSGRLGRMRDGHPCGQTXXXXXXXXXXXXSVSAHHYRRGTNTQSMLDDPLYIGLRQRRVR 320
G G LG G P G+ + GTN Q +L+D LY+GLRQ R+
Sbjct: 54 GLGDLGVQGIGIPIGKLDMYVAAAGINPQRILPIMLDVGTNNQRLLEDRLYLGLRQPRLE 113
Query: 321 GPDY----DELLDEFM----RAVVRR-----------YGQNCLV---------QFEDFGN 416
G +Y DEL++ +A+V+ Y + ++ QFEDF
Sbjct: 114 GEEYLSVVDELMEAIFTRWPKAIVQVHFFKSTTIVIFYLMHVILLTGWMGKSYQFEDFQM 173
Query: 417 ANAFRLLEKYRNKYCTFNDDIQGTAAVAVAG 509
AF L++YR K+C FNDDIQGTA VA+AG
Sbjct: 174 KWAFETLQRYRKKFCMFNDDIQGTAGVALAG 204
>UniRef50_Q95061 Cluster: Malic enzyme; n=2; Giardia
intestinalis|Rep: Malic enzyme - Giardia lamblia
(Giardia intestinalis)
Length = 557
Score = 74.1 bits (174), Expect = 3e-12
Identities = 35/84 (41%), Positives = 53/84 (63%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
G NT + +DP Y+G+ ++R + Y ++ E + AV ++ +C+ QFEDF N AF L
Sbjct: 186 GCNTDKIREDPHYLGIPEKRNKDDTYYGIIKETIEAVHSKW-PDCIFQFEDFSNDTAFTL 244
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVA 506
L+K+R+ FNDDIQGT +A A
Sbjct: 245 LKKHRDAGPVFNDDIQGTGCIAAA 268
Score = 71.3 bits (167), Expect = 2e-11
Identities = 37/75 (49%), Positives = 43/75 (57%)
Frame = +1
Query: 28 PRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTA 207
PRG ++ G V + WP + R IV TDG RILGLGDLG G I VGKL LY+
Sbjct: 111 PRGFYLNRTHLGKVKQIFDQWPYSP-RIIVATDGTRILGLGDLGTGGHQICVGKLTLYSL 169
Query: 208 LGGIKPHQCLPITID 252
GG P LPI+ D
Sbjct: 170 GGGFAPEHTLPISFD 184
>UniRef50_Q5KBK5 Cluster: Nad-dependent malic enzyme, putative; n=2;
Filobasidiella neoformans|Rep: Nad-dependent malic
enzyme, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 584
Score = 72.1 bits (169), Expect = 1e-11
Identities = 36/84 (42%), Positives = 54/84 (64%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRL 434
GTN Q +L+DPLYIG R++R+R YD+ +D+F+ +V+++ CL+ FED + L
Sbjct: 210 GTNNQDLLNDPLYIGYREKRLRDDRYDQFVDKFV-GLVKKHQPECLLHFEDLVSP---ML 265
Query: 435 LEKYRNKYCTFNDDIQGTAAVAVA 506
+ + FNDDIQGT AV +A
Sbjct: 266 NDSSEDIGARFNDDIQGTGAVTLA 289
Score = 66.1 bits (154), Expect = 7e-10
Identities = 33/81 (40%), Positives = 50/81 (61%), Gaps = 1/81 (1%)
Frame = +1
Query: 16 VYRRPRGLFITIH-DKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKL 192
++RR GL++T +K D L ++ IVV+DGE ILG+GD G+ G+GI K
Sbjct: 129 LFRRSEGLYLTPPGEKNMEEDFLDACEGRELELIVVSDGEAILGIGDQGSGGIGISGAKA 188
Query: 193 ALYTALGGIKPHQCLPITIDV 255
+Y+ + G+ P +CL IT+DV
Sbjct: 189 VIYSLIAGVDPAKCLAITLDV 209
>UniRef50_Q5C370 Cluster: Malic enzyme; n=1; Schistosoma
japonicum|Rep: Malic enzyme - Schistosoma japonicum
(Blood fluke)
Length = 264
Score = 71.3 bits (167), Expect = 2e-11
Identities = 31/63 (49%), Positives = 42/63 (66%)
Frame = +3
Query: 321 GPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRLLEKYRNKYCTFNDDIQGTAAVA 500
G +Y +DE + ++ YG N + F D N+NAF+LLE+YR Y TFNDDIQG+A V
Sbjct: 3 GEEYISFMDEVVESLSAHYGPNVCLHFADLKNSNAFQLLERYRPNYITFNDDIQGSAVVI 62
Query: 501 VAG 509
V+G
Sbjct: 63 VSG 65
>UniRef50_Q27113 Cluster: Malic enzyme; n=1; Trichomonas
vaginalis|Rep: Malic enzyme - Trichomonas vaginalis
Length = 434
Score = 66.1 bits (154), Expect = 7e-10
Identities = 34/71 (47%), Positives = 45/71 (63%)
Frame = +3
Query: 336 ELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRLLEKYRNKYCTFNDDIQGTAAVAVAGYS 515
+ + EF+ AV +G CLVQFEDF AF+LL+ +R + FNDDI+GTAAVA A +
Sbjct: 108 KFVTEFVEAVKEVFGDTCLVQFEDFEMETAFKLLDHFRWRCNCFNDDIEGTAAVAAA--T 165
Query: 516 PVSDSHRRGCP 548
S +H G P
Sbjct: 166 LASATHMEGVP 176
>UniRef50_Q2HCG7 Cluster: Malic enzyme; n=1; Chaetomium
globosum|Rep: Malic enzyme - Chaetomium globosum (Soil
fungus)
Length = 586
Score = 62.1 bits (144), Expect = 1e-08
Identities = 39/104 (37%), Positives = 54/104 (51%), Gaps = 20/104 (19%)
Frame = +1
Query: 1 QKFGLVYRRPRGLFITIHDKGHVYDVLKNWP-ETDVRAIVVT------------------ 123
+ F ++RRP+G+F+ +HD V+ L W D+ IVVT
Sbjct: 121 ENFSRLFRRPQGVFLNVHDCDRVHHDLSLWGMPDDIDYIVVTGATFHPRARSRLRYQLTK 180
Query: 124 -DGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 252
DGE ILG+GD G G+ I V KLAL T GI P++ LP+ +D
Sbjct: 181 LDGEEILGIGDQGCGGILISVAKLALMTLCAGIHPNRVLPVVLD 224
Score = 36.7 bits (81), Expect(2) = 9e-05
Identities = 13/22 (59%), Positives = 21/22 (95%)
Frame = +3
Query: 255 GTNTQSMLDDPLYIGLRQRRVR 320
GT+ +++L+DPLY+GLR++RVR
Sbjct: 226 GTDNETLLNDPLYLGLREKRVR 247
Score = 31.9 bits (69), Expect(2) = 9e-05
Identities = 14/28 (50%), Positives = 19/28 (67%)
Frame = +3
Query: 423 AFRLLEKYRNKYCTFNDDIQGTAAVAVA 506
A RLL+++R FNDD+QGT V +A
Sbjct: 248 ARRLLDRWRPDIPCFNDDVQGTGCVTLA 275
>UniRef50_A7R628 Cluster: Chromosome undetermined scaffold_1141,
whole genome shotgun sequence; n=3; Vitis vinifera|Rep:
Chromosome undetermined scaffold_1141, whole genome
shotgun sequence - Vitis vinifera (Grape)
Length = 236
Score = 60.5 bits (140), Expect = 3e-08
Identities = 30/81 (37%), Positives = 43/81 (53%)
Frame = +3
Query: 267 QSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRLLEKY 446
++ D +G +Y E L EFM AV + YG+ + +FED+ N NAF LL +Y
Sbjct: 109 EAFCSDDSDVGFPTNNHASEEYSEFLHEFMSAVNQNYGEK-VTRFEDYANHNAFELLARY 167
Query: 447 RNKYCTFNDDIQGTAAVAVAG 509
+ N DIQGT V ++G
Sbjct: 168 NTTHLVPNGDIQGTTYVVLSG 188
>UniRef50_A5B3Q7 Cluster: Malic enzyme; n=1; Vitis vinifera|Rep:
Malic enzyme - Vitis vinifera (Grape)
Length = 176
Score = 55.6 bits (128), Expect = 1e-06
Identities = 26/63 (41%), Positives = 37/63 (58%)
Frame = +3
Query: 321 GPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRLLEKYRNKYCTFNDDIQGTAAVA 500
G +Y E L +FM V + YG+ + +FED+ N NAF LL +Y + N DIQ T V
Sbjct: 78 GKEYSEFLHKFMSTVKQNYGEK-VTRFEDYANHNAFELLARYNTTHLVPNGDIQXTTYVV 136
Query: 501 VAG 509
++G
Sbjct: 137 LSG 139
>UniRef50_Q8S484 Cluster: Putative NADP-dependent malic enzyme; n=1;
Zea mays|Rep: Putative NADP-dependent malic enzyme - Zea
mays (Maize)
Length = 309
Score = 53.6 bits (123), Expect = 4e-06
Identities = 23/33 (69%), Positives = 26/33 (78%)
Frame = +1
Query: 61 GHVYDVLKNWPETDVRAIVVTDGERILGLGDLG 159
G V DVLKNWP +++ I VTD ERILGLGDLG
Sbjct: 249 GKVLDVLKNWPHRNIQVIFVTDSERILGLGDLG 281
>UniRef50_Q3W7J3 Cluster: Malate dehydrogenase; n=1; Frankia sp.
EAN1pec|Rep: Malate dehydrogenase - Frankia sp. EAN1pec
Length = 464
Score = 41.5 bits (93), Expect = 0.017
Identities = 22/48 (45%), Positives = 30/48 (62%), Gaps = 1/48 (2%)
Frame = +1
Query: 112 IVVTDGERILGLGDLG-ACGMGIPVGKLALYTALGGIKPHQCLPITID 252
IVVTDG +LGLGD+G A + + GK AL+ GG+ +PI +D
Sbjct: 142 IVVTDGTAVLGLGDIGPAAALPVMEGKAALFKHFGGV---DAVPICLD 186
>UniRef50_Q8U225 Cluster: Malate oxidoreductase; n=41; cellular
organisms|Rep: Malate oxidoreductase - Pyrococcus
furiosus
Length = 435
Score = 41.5 bits (93), Expect = 0.017
Identities = 24/47 (51%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
Frame = +1
Query: 115 VVTDGERILGLGDLGA-CGMGIPVGKLALYTALGGIKPHQCLPITID 252
VVTDG ILGLG++G GM + GK L+ AL GI PI ID
Sbjct: 77 VVTDGSAILGLGNIGVLAGMPVMEGKCVLFKALAGI---DAFPILID 120
>UniRef50_Q5Y0M3 Cluster: Malate oxidoreductase; n=8; cellular
organisms|Rep: Malate oxidoreductase - uncultured
archaeon GZfos12E1
Length = 444
Score = 39.9 bits (89), Expect = 0.051
Identities = 20/47 (42%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
Frame = +1
Query: 115 VVTDGERILGLGDLGA-CGMGIPVGKLALYTALGGIKPHQCLPITID 252
+VTDG R+LGLGD+GA + + GK L+ LGG+ P+ +D
Sbjct: 84 IVTDGTRVLGLGDVGAEAALPVMEGKAMLFKYLGGV---DAFPLCLD 127
>UniRef50_P54572 Cluster: Probable NAD-dependent malic enzyme 1;
n=4; Bacteria|Rep: Probable NAD-dependent malic enzyme 1
- Bacillus subtilis
Length = 439
Score = 39.9 bits (89), Expect = 0.051
Identities = 22/47 (46%), Positives = 30/47 (63%), Gaps = 1/47 (2%)
Frame = +1
Query: 115 VVTDGERILGLGDLGA-CGMGIPVGKLALYTALGGIKPHQCLPITID 252
+VTDG ILGLG++G+ GM + GK AL+ L GI +PI +D
Sbjct: 142 IVTDGTAILGLGNIGSVAGMPVMEGKAALFDQLAGISG---IPILLD 185
>UniRef50_Q2KKD0 Cluster: Oxalacetate decarboxylase; n=11;
Lactobacillales|Rep: Oxalacetate decarboxylase -
Enterococcus faecalis (Streptococcus faecalis)
Length = 390
Score = 39.1 bits (87), Expect = 0.090
Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Frame = +1
Query: 70 YDVLKNWPETDVRAIVVTDGERILGLGDLGA-CGMGIPVGKLALYTALGGI 219
+++ + W + V+TDG +LGLG++G G+ I GK LY L G+
Sbjct: 49 HELAREWTISGKLIAVITDGSAVLGLGNMGTQAGLPIVEGKALLYKNLAGV 99
>UniRef50_A0DE35 Cluster: Malic enzyme; n=3; Paramecium
tetraurelia|Rep: Malic enzyme - Paramecium tetraurelia
Length = 687
Score = 39.1 bits (87), Expect = 0.090
Identities = 18/38 (47%), Positives = 27/38 (71%), Gaps = 1/38 (2%)
Frame = +1
Query: 109 AIVVTDGERILGLGDLG-ACGMGIPVGKLALYTALGGI 219
A ++T+G ILGLG++G + G+ + GK L+ ALGGI
Sbjct: 337 AAIITNGTAILGLGNIGPSAGLPVMEGKSVLFNALGGI 374
>UniRef50_A5C5G3 Cluster: Malic enzyme; n=1; Vitis vinifera|Rep:
Malic enzyme - Vitis vinifera (Grape)
Length = 226
Score = 38.3 bits (85), Expect = 0.16
Identities = 17/40 (42%), Positives = 23/40 (57%)
Frame = +3
Query: 390 LVQFEDFGNANAFRLLEKYRNKYCTFNDDIQGTAAVAVAG 509
+ +FED N NAF LL +Y + N DIQGT ++G
Sbjct: 5 VTRFEDSANHNAFELLARYHTTHLVPNGDIQGTTFXVLSG 44
>UniRef50_Q9HKY7 Cluster: Malate oxidoreductase (Malic enzyme)
related protein; n=17; Archaea|Rep: Malate
oxidoreductase (Malic enzyme) related protein -
Thermoplasma acidophilum
Length = 467
Score = 36.7 bits (81), Expect = 0.48
Identities = 19/48 (39%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
Frame = +1
Query: 115 VVTDGERILGLGDLG-ACGMGIPVGKLALYTALGGIKPHQCLPITIDV 255
++TDG R+LGLG++G M + GK ++ LGG+ +PI I V
Sbjct: 94 ILTDGTRVLGLGNIGPEAAMPVMEGKALIFNYLGGV---NAIPIPIRV 138
>UniRef50_Q22974 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 980
Score = 35.5 bits (78), Expect = 1.1
Identities = 21/71 (29%), Positives = 31/71 (43%), Gaps = 2/71 (2%)
Frame = +3
Query: 378 GQNCLVQFEDFGNANAFRLLEKYRNKYCTFNDDIQGTAAVAVAGYSPVSDSHRRGCPTTS 557
G NC V+ D + E +N+ D++ G P+SD R P+TS
Sbjct: 87 GNNCSVRIRDRTEEMRKLMDENAKNRPVRIVDNVHGVPITEFTHIVPISDQERDDGPSTS 146
Query: 558 SS--SREPERP 584
S +REP +P
Sbjct: 147 GSYPNREPAQP 157
>UniRef50_Q0CJN2 Cluster: Predicted protein; n=3;
Trichocomaceae|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 680
Score = 34.7 bits (76), Expect = 1.9
Identities = 18/44 (40%), Positives = 22/44 (50%)
Frame = +2
Query: 143 VWATWAHAGWASLWANSRSTPRSEASSRISVCPSLSTWYEHPVD 274
V A+WA AG A LW R++A I S S YE+P D
Sbjct: 332 VEASWATAGSAGLWTPREELNRTDADVSIFFLNSNSVTYEYPTD 375
>UniRef50_Q2STW7 Cluster: Putative uncharacterized protein; n=1;
Burkholderia thailandensis E264|Rep: Putative
uncharacterized protein - Burkholderia thailandensis
(strain E264 / ATCC 700388 / DSM 13276 /CIP 106301)
Length = 647
Score = 34.3 bits (75), Expect = 2.6
Identities = 17/43 (39%), Positives = 22/43 (51%)
Frame = +1
Query: 73 DVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALY 201
DVL+ +P T V DG + GLG+L CG P +L Y
Sbjct: 97 DVLRQFPHTYVERSPSGDGLHLFGLGELVECGKAGPGNRLECY 139
>UniRef50_Q87075 Cluster: Glycoprotein gX; n=1; Suid herpesvirus
1|Rep: Glycoprotein gX - Suid herpesvirus 1
(Pseudorabies virus)
Length = 103
Score = 33.9 bits (74), Expect = 3.4
Identities = 23/68 (33%), Positives = 34/68 (50%)
Frame = +2
Query: 20 TADQGASSSRSTIRDMYTMFLRTGRRRTSAPLL*PTENVFWVWATWAHAGWASLWANSRS 199
+A ASSSRS R R R TSAP + + W++WA + AS+W +S
Sbjct: 2 SAPSAASSSRSRPRPPTPPPPRRACRATSAPRS-TSASPSPAWSSWASSSCASIWRSSGP 60
Query: 200 TPRSEASS 223
P + A++
Sbjct: 61 GPGTTATA 68
>UniRef50_Q8R7R6 Cluster: Malic enzyme; n=10; cellular
organisms|Rep: Malic enzyme - Thermoanaerobacter
tengcongensis
Length = 394
Score = 33.9 bits (74), Expect = 3.4
Identities = 16/36 (44%), Positives = 22/36 (61%), Gaps = 1/36 (2%)
Frame = +1
Query: 115 VVTDGERILGLGDLGA-CGMGIPVGKLALYTALGGI 219
VVTDG +LGLG++G + + GK L+ GGI
Sbjct: 66 VVTDGSAVLGLGNIGPYAALPVMEGKAVLFKEFGGI 101
>UniRef50_Q5SLE4 Cluster: CBS domain protein; n=7; Bacteria|Rep: CBS
domain protein - Thermus thermophilus (strain HB8 / ATCC
27634 / DSM 579)
Length = 143
Score = 33.9 bits (74), Expect = 3.4
Identities = 14/33 (42%), Positives = 22/33 (66%)
Frame = +1
Query: 49 IHDKGHVYDVLKNWPETDVRAIVVTDGERILGL 147
IH + V D L+ E D+ A++V +GER+LG+
Sbjct: 17 IHPEATVLDALRKLAEHDIGALLVMEGERLLGI 49
>UniRef50_Q0STR8 Cluster: Malate oxidoreductase; n=2; Clostridium
perfringens|Rep: Malate oxidoreductase - Clostridium
perfringens (strain SM101 / Type A)
Length = 381
Score = 33.9 bits (74), Expect = 3.4
Identities = 20/66 (30%), Positives = 31/66 (46%), Gaps = 1/66 (1%)
Frame = +1
Query: 64 HVYDVLKNWPETDVRAIVVTDGERILGLGDLGA-CGMGIPVGKLALYTALGGIKPHQCLP 240
H +LK V+TDG +LGLG++G G I K +Y L G+ +P
Sbjct: 48 HHPSMLKTLTSVGNSIAVITDGTAVLGLGNIGTLAGYPIVEAKALVYKDLAGV---NAIP 104
Query: 241 ITIDVV 258
+ +D +
Sbjct: 105 LCVDQI 110
>UniRef50_Q3URU3 Cluster: ES cells cDNA, RIKEN full-length enriched
library, clone:C330011E08 product:hypothetical protein,
full insert sequence; n=1; Mus musculus|Rep: ES cells
cDNA, RIKEN full-length enriched library,
clone:C330011E08 product:hypothetical protein, full
insert sequence - Mus musculus (Mouse)
Length = 120
Score = 33.5 bits (73), Expect = 4.5
Identities = 16/41 (39%), Positives = 22/41 (53%)
Frame = +3
Query: 495 VAVAGYSPVSDSHRRGCPTTSSSSREPERPLWVSRNCALWP 617
+ V G P+ S G S+SR +PLW SR+CA+ P
Sbjct: 75 LCVGGGLPLPASSAAGYGKDRSASRVKPKPLWKSRDCAMGP 115
>UniRef50_A4AEE1 Cluster: Dihydroorotase and related cyclic
amidohydrolase; n=1; marine actinobacterium
PHSC20C1|Rep: Dihydroorotase and related cyclic
amidohydrolase - marine actinobacterium PHSC20C1
Length = 470
Score = 33.5 bits (73), Expect = 4.5
Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Frame = +1
Query: 10 GLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGL--GDLGACGMGIPV 183
G Y P G IHD GH+ ++ +TD+R I+ + ++ G++ A G P
Sbjct: 153 GRDYPHPAGT--GIHDHGHLLQIMDQIAKTDIRFIIHPHDQGLMDYIEGEVLARGDNTPE 210
Query: 184 GKLALYTALGGI 219
G + Y A G+
Sbjct: 211 GYASAYAAREGV 222
>UniRef50_A3EUF6 Cluster: ATP-dependent endonuclease; n=1;
Leptospirillum sp. Group II UBA|Rep: ATP-dependent
endonuclease - Leptospirillum sp. Group II UBA
Length = 657
Score = 33.5 bits (73), Expect = 4.5
Identities = 14/34 (41%), Positives = 18/34 (52%)
Frame = +1
Query: 184 GKLALYTALGGIKPHQCLPITIDVVRTPSRCWTT 285
GK A+ AL G+ PH P+ D+ R R W T
Sbjct: 35 GKTAILQALAGLNPHPLTPVNYDLERDYPRRWLT 68
>UniRef50_P16468 Cluster: NAD-dependent malic enzyme; n=32;
Bacteria|Rep: NAD-dependent malic enzyme - Bacillus
stearothermophilus (Geobacillus stearothermophilus)
Length = 478
Score = 33.5 bits (73), Expect = 4.5
Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 1/51 (1%)
Frame = +1
Query: 115 VVTDGERILGLGDLGA-CGMGIPVGKLALYTALGGIKPHQCLPITIDVVRT 264
VV+DG +LGLGD+G M + GK L+ G+ PI +D T
Sbjct: 144 VVSDGTAVLGLGDIGPYAAMPVMEGKAMLFKEFAGV---DAFPICLDTKDT 191
>UniRef50_UPI00006CF21C Cluster: Bowman-Birk serine protease
inhibitor family protein; n=1; Tetrahymena thermophila
SB210|Rep: Bowman-Birk serine protease inhibitor family
protein - Tetrahymena thermophila SB210
Length = 1467
Score = 33.1 bits (72), Expect = 5.9
Identities = 20/59 (33%), Positives = 26/59 (44%)
Frame = +1
Query: 79 LKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDV 255
L NW IVV+ G + L LG G +P + + G+ PH L TIDV
Sbjct: 208 LVNWTCLQKNVIVVSGGIQNWALTSLGPLGQNVPASR-----TISGLTPHNQLIFTIDV 261
>UniRef50_UPI0000DA40E4 Cluster: PREDICTED: hypothetical protein;
n=2; Rattus norvegicus|Rep: PREDICTED: hypothetical
protein - Rattus norvegicus
Length = 193
Score = 32.7 bits (71), Expect = 7.8
Identities = 20/51 (39%), Positives = 24/51 (47%)
Frame = -2
Query: 184 PQGCPSRMRPSRPDPEYVLRRLQQWRGRPSPASS*EHRIHVPYRGS**RGP 32
P C R +RP P R WRG P+P + + R P RGS RGP
Sbjct: 106 PTPCKRTPRRTRPAPCSARR----WRGHPAPRAQWQRREGRPRRGSQARGP 152
>UniRef50_Q1EI20 Cluster: Putative uncharacterized protein; n=2;
root|Rep: Putative uncharacterized protein - uncultured
organism
Length = 302
Score = 32.7 bits (71), Expect = 7.8
Identities = 10/20 (50%), Positives = 16/20 (80%)
Frame = +1
Query: 34 GLFITIHDKGHVYDVLKNWP 93
G+++TI + G + D+LKNWP
Sbjct: 210 GVYLTIREPGQITDILKNWP 229
>UniRef50_Q2Y6H5 Cluster: Response regulator receiver domain
protein; n=1; Nitrosospira multiformis ATCC 25196|Rep:
Response regulator receiver domain protein -
Nitrosospira multiformis (strain ATCC 25196 / NCIMB
11849)
Length = 412
Score = 32.7 bits (71), Expect = 7.8
Identities = 18/63 (28%), Positives = 30/63 (47%), Gaps = 1/63 (1%)
Frame = +3
Query: 345 DEFMRAVVRRYGQNCLVQFEDFGNANAFRLLEKYRNKYCTFNDDI-QGTAAVAVAGYSPV 521
DE +R +V RY +N + +D + ++ + N Y + QG A +A SPV
Sbjct: 326 DEKIRLIVNRYKKNADITLDDIESTLNLKIFKVVPNDYAVVTGSVNQGIPATKLAPRSPV 385
Query: 522 SDS 530
+ S
Sbjct: 386 AKS 388
>UniRef50_Q4Q3I8 Cluster: Putative uncharacterized protein; n=3;
Leishmania|Rep: Putative uncharacterized protein -
Leishmania major
Length = 517
Score = 32.7 bits (71), Expect = 7.8
Identities = 15/40 (37%), Positives = 24/40 (60%)
Frame = +3
Query: 399 FEDFGNANAFRLLEKYRNKYCTFNDDIQGTAAVAVAGYSP 518
F+D+GN FRL++K + ++ +ND A V V +SP
Sbjct: 425 FKDYGNGLVFRLVDKVQRRWAFYNDTTDIVALVRVQ-FSP 463
>UniRef50_P27536 Cluster: Posterior protein; n=4; Xenopus|Rep:
Posterior protein - Xenopus laevis (African clawed frog)
Length = 555
Score = 32.7 bits (71), Expect = 7.8
Identities = 16/58 (27%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Frame = +2
Query: 20 TADQGASSSRSTIRDMYTMFLRTGRRRTSAPLL*PTENV-FWVWATWAHAGWASLWAN 190
+A S R+ +T +TG+ T+AP P N+ W++++W+H L N
Sbjct: 482 SAGDQKESQNEPKREFHTPPCKTGKEGTTAPPFIPWVNIPLWLYSSWSHIAMLMLMDN 539
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 592,077,997
Number of Sequences: 1657284
Number of extensions: 12117445
Number of successful extensions: 43029
Number of sequences better than 10.0: 89
Number of HSP's better than 10.0 without gapping: 41122
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 42960
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 48541014171
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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