Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= e40h0387
(694 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P0AFG7 Cluster: Dihydrolipoyllysine-residue succinyltra... 180 3e-44
UniRef50_Q8DFQ0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 171 1e-41
UniRef50_Q89AJ6 Cluster: Dihydrolipoyllysine-residue succinyltra... 140 3e-32
UniRef50_P57389 Cluster: Dihydrolipoyllysine-residue succinyltra... 134 1e-30
UniRef50_Q63TQ8 Cluster: Dihydrolipoamide succinyltransferase co... 132 8e-30
UniRef50_A4BP63 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 129 6e-29
UniRef50_Q82SG4 Cluster: SucB; dihydrolipoamide succinyltransfer... 128 1e-28
UniRef50_A6DL93 Cluster: Dihydrolipoamide acetyltransferase; n=1... 122 8e-27
UniRef50_A0M5Y1 Cluster: Dihydrolipoyllysine-residue succinyltra... 121 1e-26
UniRef50_Q057P2 Cluster: 2-oxoglutarate dehydrogenase E2 compone... 120 3e-26
UniRef50_Q1E5N3 Cluster: Dihydrolipoyllysine-residue succinyltra... 118 1e-25
UniRef50_Q39RZ0 Cluster: Dihydrolipoamide succinyltransferase; n... 118 2e-25
UniRef50_Q6FYD4 Cluster: Dihydrolipoyllysine-residue succinyltra... 118 2e-25
UniRef50_A5EW59 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 117 2e-25
UniRef50_Q4UKI7 Cluster: Dihydrolipoyllysine-residue succinyltra... 117 2e-25
UniRef50_A6SDP7 Cluster: Putative uncharacterized protein; n=1; ... 116 5e-25
UniRef50_P19262 Cluster: Dihydrolipoyllysine-residue succinyltra... 116 7e-25
UniRef50_Q98ED1 Cluster: Dihydrolipoamide succinyl transferase; ... 114 2e-24
UniRef50_Q7ULX6 Cluster: Dihydrolipoamide succinyltransferase co... 114 2e-24
UniRef50_P36957 Cluster: Dihydrolipoyllysine-residue succinyltra... 114 2e-24
UniRef50_A0LAA3 Cluster: 2-oxoglutarate dehydrogenase, E2 subuni... 113 5e-24
UniRef50_Q9FLQ4 Cluster: 2-oxoglutarate dehydrogenase E2 subunit... 113 5e-24
UniRef50_A5CEI9 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 112 7e-24
UniRef50_Q3SEX1 Cluster: Dihydrolipoamide succinyltransferase; n... 111 2e-23
UniRef50_Q553V8 Cluster: Dihydrolipoamide S-succinyltransferase;... 111 2e-23
UniRef50_Q49XM4 Cluster: Dihydrolipoyllysine-residue succinyltra... 111 2e-23
UniRef50_Q1QQR6 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 110 3e-23
UniRef50_Q4RLV1 Cluster: Chromosome 10 SCAF15019, whole genome s... 110 4e-23
UniRef50_Q5P9T5 Cluster: Dihydrolipoamide acetyltransferase comp... 110 4e-23
UniRef50_UPI00015B5B2E Cluster: PREDICTED: similar to ENSANGP000... 109 6e-23
UniRef50_O84058 Cluster: Dihydrolipoamide Succinyltransferase; n... 108 1e-22
UniRef50_Q234F3 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 108 1e-22
UniRef50_Q2UQN3 Cluster: Dihydrolipoamide succinyltransferase; n... 108 1e-22
UniRef50_A0LP66 Cluster: 2-oxoglutarate dehydrogenase, E2 subuni... 106 4e-22
UniRef50_A0H458 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 106 4e-22
UniRef50_O94681 Cluster: Probable dihydrolipoyllysine-residue su... 105 1e-21
UniRef50_Q5FS04 Cluster: Dihydrolipoamide succinyl transferase (... 104 2e-21
UniRef50_Q4Q822 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 104 2e-21
UniRef50_Q7RIU5 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 103 3e-21
UniRef50_Q3A0D1 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 102 7e-21
UniRef50_P16263 Cluster: Dihydrolipoyllysine-residue succinyltra... 102 7e-21
UniRef50_Q6MC86 Cluster: Probable dihydrolipoamide S-succinyltra... 100 3e-20
UniRef50_Q0E0X4 Cluster: Os02g0514700 protein; n=2; Oryza sativa... 99 5e-20
UniRef50_Q4UGK1 Cluster: Dihydrolipoamide succinyltransferase co... 99 1e-19
UniRef50_A7AQM6 Cluster: Dihydrolipoamide succinyltransferase, p... 96 6e-19
UniRef50_UPI000023F136 Cluster: hypothetical protein FG10947.1; ... 92 1e-17
UniRef50_A6WD54 Cluster: 2-oxoglutarate dehydrogenase E2 compone... 86 7e-16
UniRef50_A0LSF1 Cluster: Catalytic domain of components of vario... 81 2e-14
UniRef50_Q0RVL0 Cluster: Dihydrolipoyllysine-residue succinyltra... 80 6e-14
UniRef50_Q8RD59 Cluster: Dihydrolipoamide acyltransferases; n=1;... 78 2e-13
UniRef50_Q8R9E5 Cluster: Dihydrolipoamide acyltransferases; n=3;... 78 2e-13
UniRef50_Q73FZ4 Cluster: Pyruvate dehydrogenase complex, E2 comp... 78 2e-13
UniRef50_Q9KES1 Cluster: Dihydrolipoamide S-acetyltransferase; n... 78 2e-13
UniRef50_Q67ME8 Cluster: Branched-chain alpha-keto acid dehydrog... 77 4e-13
UniRef50_Q47KD8 Cluster: Pyruvate dehydrogenase complex, E2 comp... 77 4e-13
UniRef50_A6DTS5 Cluster: Pyruvate dehydrogenase complex , E2 com... 77 4e-13
UniRef50_Q1Q664 Cluster: Similar to 2-oxoglutarate dehydrogenase... 76 7e-13
UniRef50_Q9RYB8 Cluster: 2-oxo acid dehydrogenase, E2 component;... 76 1e-12
UniRef50_Q0W153 Cluster: Pyruvate dehydrogenase complex E2, dihy... 76 1e-12
UniRef50_Q0SJA7 Cluster: Dihydrolipoyllysine-residue succinyltra... 75 1e-12
UniRef50_Q9YBC6 Cluster: Pyruvate dehydrogenase complex, E2 comp... 75 2e-12
UniRef50_Q49110 Cluster: Dihydrolipoyllysine-residue acetyltrans... 75 2e-12
UniRef50_Q8AB01 Cluster: Lipoamide acyltransferase component of ... 75 2e-12
UniRef50_Q9X6X2 Cluster: Lipoamide acyltransferase; n=3; Cystoba... 75 2e-12
UniRef50_A1SJ23 Cluster: Catalytic domain of components of vario... 75 2e-12
UniRef50_Q6PLQ2 Cluster: Dihydrolipoamide S-acetyltransferase; n... 75 2e-12
UniRef50_Q97Y19 Cluster: Dihydrolipoamide S-acetyltransferase, c... 75 2e-12
UniRef50_Q6MPR6 Cluster: Pyruvate dehydrogenase E2; n=1; Bdellov... 74 3e-12
UniRef50_Q1AT73 Cluster: Catalytic domain of components of vario... 74 3e-12
UniRef50_A6GB59 Cluster: Alpha keto acid dehydrogenase complex, ... 74 3e-12
UniRef50_Q5UYG4 Cluster: Dihydrolipoamide acetyltransferase comp... 74 3e-12
UniRef50_P37942 Cluster: Lipoamide acyltransferase component of ... 74 4e-12
UniRef50_A7HHV9 Cluster: Pyruvate dehydrogenase complex dihydrol... 73 5e-12
UniRef50_A3HTS0 Cluster: 2-oxo acid dehydrogenases acyltransfera... 73 5e-12
UniRef50_Q3VZH8 Cluster: Biotin/lipoyl attachment:Catalytic doma... 73 7e-12
UniRef50_A3WC78 Cluster: Pyruvate dehydrogenase E2 component; n=... 73 7e-12
UniRef50_Q5KUY3 Cluster: Pyruvate dehydrogenase E2; n=2; Geobaci... 73 9e-12
UniRef50_Q3CI28 Cluster: Biotin/lipoyl attachment:Catalytic doma... 73 9e-12
UniRef50_A7BC27 Cluster: Putative uncharacterized protein; n=1; ... 73 9e-12
UniRef50_Q749T6 Cluster: Pyruvate dehydrogenase complex E2 compo... 72 1e-11
UniRef50_Q4L6L6 Cluster: Branched-chain alpha-keto acid dehydrog... 72 1e-11
UniRef50_Q18CC2 Cluster: E2 component of acetoin dehydrogenase e... 72 1e-11
UniRef50_A1SQ65 Cluster: Catalytic domain of components of vario... 72 1e-11
UniRef50_A5MZI5 Cluster: PdhC; n=6; Clostridium|Rep: PdhC - Clos... 72 2e-11
UniRef50_A2WZU5 Cluster: Putative uncharacterized protein; n=2; ... 72 2e-11
UniRef50_O45279 Cluster: Putative uncharacterized protein; n=2; ... 72 2e-11
UniRef50_P65634 Cluster: Dihydrolipoyllysine-residue succinyltra... 72 2e-11
UniRef50_Q83G30 Cluster: Dihydrolipoamide succinyltransferase co... 71 2e-11
UniRef50_Q2S152 Cluster: Dihydrolipoyllysine-residue acetyltrans... 71 2e-11
UniRef50_Q9HN75 Cluster: Dihydrolipoamide S-acetyltransferase; n... 71 2e-11
UniRef50_Q92BY1 Cluster: Lin1411 protein; n=15; Bacillales|Rep: ... 71 3e-11
UniRef50_A5UTW4 Cluster: Catalytic domain of components of vario... 71 3e-11
UniRef50_Q2S4D4 Cluster: 2-oxo acid dehydrogenases acyltransfera... 71 4e-11
UniRef50_Q0LRZ3 Cluster: Dihydrolipoamide acetyltransferase, lon... 71 4e-11
UniRef50_Q9XYS5 Cluster: Dihydrolipoyl dehydrogenase-binding pro... 71 4e-11
UniRef50_Q67SE5 Cluster: Pyruvate dehydrogenase E2; n=1; Symbiob... 70 5e-11
UniRef50_A0LLM2 Cluster: Catalytic domain of components of vario... 70 5e-11
UniRef50_Q6KH63 Cluster: Pyruvate dehydrogenase E2 component dih... 70 6e-11
UniRef50_O32959 Cluster: Dihydrolipoamide succinyltransferase; n... 70 6e-11
UniRef50_A6UGY8 Cluster: Dihydrolipoyllysine-residue succinyltra... 70 6e-11
UniRef50_A1UIB1 Cluster: Catalytic domain of components of vario... 70 6e-11
UniRef50_Q2JA39 Cluster: Dehydrogenase subunit; n=4; Actinomycet... 69 8e-11
UniRef50_Q5KIM3 Cluster: Dihydrolipoyllysine-residue acetyltrans... 69 8e-11
UniRef50_Q1IIF0 Cluster: Dihydrolipoamide S-succinyltransferase;... 69 1e-10
UniRef50_Q2GI07 Cluster: Pyruvate dehydrogenase complex, E2 comp... 69 1e-10
UniRef50_Q92HK7 Cluster: Dihydrolipoyllysine-residue acetyltrans... 69 1e-10
UniRef50_Q39ET0 Cluster: Dihydrolipoamide acetyltransferase; n=4... 68 2e-10
UniRef50_Q65MC9 Cluster: AcoC; n=1; Bacillus licheniformis ATCC ... 68 3e-10
UniRef50_A3U7C0 Cluster: Lipoamide acyltransferase component of ... 68 3e-10
UniRef50_Q8YDW4 Cluster: DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMP... 67 3e-10
UniRef50_Q3JBP0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 67 3e-10
UniRef50_Q7D716 Cluster: 2-oxoisovalerate dehydrogenase E2 compo... 67 3e-10
UniRef50_Q1AZ52 Cluster: Catalytic domain of components of vario... 67 3e-10
UniRef50_A0LQU7 Cluster: Catalytic domain of components of vario... 67 3e-10
UniRef50_A4AGT3 Cluster: Putative dihydrolipoamide acyltransfera... 67 4e-10
UniRef50_Q1EGH5 Cluster: Pyruvate dehydrogenase E2 subunit; n=3;... 67 4e-10
UniRef50_Q8F4N2 Cluster: Dihydrolipoamide acetyltransferase comp... 66 6e-10
UniRef50_Q14PD7 Cluster: Putative dihydrolipoyllysine-residue ac... 66 6e-10
UniRef50_A7HBV2 Cluster: Dehydrogenase complex catalytic domain;... 66 6e-10
UniRef50_A1ZHD0 Cluster: Dihydrolipoyllysine-residue succinyltra... 66 6e-10
UniRef50_A4RXN8 Cluster: Predicted protein; n=3; cellular organi... 66 6e-10
UniRef50_Q8ZUR6 Cluster: Pyruvate dehydrogenase E2; n=1; Pyrobac... 66 6e-10
UniRef50_Q820A3 Cluster: AceF; dihydrolipoamide acetyltransferas... 66 8e-10
UniRef50_Q08V09 Cluster: Pyruvate dehydrogenase complex dihydrol... 66 8e-10
UniRef50_Q8CX89 Cluster: Pyruvate dehydrogenase E2; n=4; Bacilla... 66 1e-09
UniRef50_Q48TW1 Cluster: Dihydrolipoamide acetyltransferase comp... 66 1e-09
UniRef50_Q1YS54 Cluster: Dihydrolipoamide acetyltransferase; n=1... 66 1e-09
UniRef50_Q1IMV8 Cluster: Dihydrolipoamide acetyltransferase; n=1... 66 1e-09
UniRef50_Q088Y7 Cluster: Dihydrolipoyllysine-residue succinyltra... 66 1e-09
UniRef50_Q5UWH1 Cluster: Dihydrolipoamide S-acetyltransferase co... 65 1e-09
UniRef50_A4WK39 Cluster: Catalytic domain of components of vario... 65 1e-09
UniRef50_O31550 Cluster: Dihydrolipoyllysine-residue acetyltrans... 65 1e-09
UniRef50_Q9PKE7 Cluster: Pyruvate dehydrogenase, E2 component, d... 65 2e-09
UniRef50_Q74AE1 Cluster: Dehydrogenase complex E2 component, dih... 65 2e-09
UniRef50_Q1GTH9 Cluster: Catalytic domain of components of vario... 65 2e-09
UniRef50_A6C4P4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 65 2e-09
UniRef50_A3VK82 Cluster: Putative uncharacterized protein; n=1; ... 65 2e-09
UniRef50_A0M206 Cluster: Dihydrolipoyllysine-residue acetyltrans... 65 2e-09
UniRef50_Q5L233 Cluster: Pyruvate dehydrogenase E2; n=2; Geobaci... 64 2e-09
UniRef50_A4CQ51 Cluster: Lipoamide acyltransferase component of ... 64 2e-09
UniRef50_A1SQB9 Cluster: Catalytic domain of components of vario... 64 2e-09
UniRef50_A1R9E2 Cluster: Pyruvate dehydrogenase E2; n=2; Actinom... 64 2e-09
UniRef50_Q19749 Cluster: Dihydrolipoyllysine-residue acetyltrans... 64 2e-09
UniRef50_UPI00015A4520 Cluster: UPI00015A4520 related cluster; n... 64 4e-09
UniRef50_A5V4B2 Cluster: Catalytic domain of components of vario... 64 4e-09
UniRef50_A3UGB6 Cluster: Dihydrolipoamide acetyltransferase; n=2... 64 4e-09
UniRef50_Q6KCM0 Cluster: Dihydrolipoyl transacetylase; n=1; Eugl... 64 4e-09
UniRef50_A4S3G1 Cluster: Predicted protein; n=2; Ostreococcus|Re... 64 4e-09
UniRef50_O00330 Cluster: Pyruvate dehydrogenase protein X compon... 64 4e-09
UniRef50_Q9I1M0 Cluster: Lipoamide acyltransferase component of ... 64 4e-09
UniRef50_O84249 Cluster: Dihydrolipoamide Acetyltransferase; n=7... 63 5e-09
UniRef50_Q5DAR0 Cluster: SJCHGC04873 protein; n=1; Schistosoma j... 63 5e-09
UniRef50_UPI0000ECB9E1 Cluster: Apoptosis inhibitor 5 (API-5).; ... 63 7e-09
UniRef50_Q8RBW8 Cluster: Dihydrolipoamide acyltransferases; n=1;... 63 7e-09
UniRef50_Q9KG97 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillu... 62 9e-09
UniRef50_Q8EJN8 Cluster: Pyruvate dehydrogenase complex, E2 comp... 62 9e-09
UniRef50_Q0LND0 Cluster: Dihydrolipoamide S-succinyltransferase;... 62 9e-09
UniRef50_A4A156 Cluster: Pyruvate dehydrogenase, E2 component, d... 62 9e-09
UniRef50_A0YCP9 Cluster: Pyruvate dehydrogenase complex dihydrol... 62 9e-09
UniRef50_Q4QJI5 Cluster: Dihydrolipoamide branched chain transac... 62 9e-09
UniRef50_Q97CK2 Cluster: Pyruvate dehydrogenase E2 / dihydrolipo... 62 9e-09
UniRef50_O66119 Cluster: Dihydrolipoyllysine-residue acetyltrans... 62 9e-09
UniRef50_P35489 Cluster: Dihydrolipoyllysine-residue acetyltrans... 62 9e-09
UniRef50_Q2J8A0 Cluster: Dehydrogenase subunit; n=9; Actinobacte... 62 1e-08
UniRef50_Q03Y73 Cluster: Acetoin/pyruvate dehydrogenase complex,... 62 1e-08
UniRef50_A2TU26 Cluster: Lipoamide acyltransferase component of ... 62 1e-08
UniRef50_A0NRH8 Cluster: Branched-chain alpha-keto acid dehydrog... 62 1e-08
UniRef50_P20285 Cluster: Dihydrolipoyllysine-residue acetyltrans... 62 1e-08
UniRef50_P36413 Cluster: Dihydrolipoyllysine-residue acetyltrans... 62 1e-08
UniRef50_Q2GCH9 Cluster: Pyruvate dehydrogenase complex, E2 comp... 62 2e-08
UniRef50_A6TMP1 Cluster: Catalytic domain of components of vario... 62 2e-08
UniRef50_Q8RWN9 Cluster: Dihydrolipoyllysine-residue acetyltrans... 62 2e-08
UniRef50_UPI0000DB7177 Cluster: PREDICTED: similar to Pyruvate d... 61 2e-08
UniRef50_Q7WED2 Cluster: Probable 2-oxo acid dehydrogenases acyl... 61 2e-08
UniRef50_Q5ZVD7 Cluster: Pyruvate dehydrogenase E2 component; n=... 61 2e-08
UniRef50_A0JZU9 Cluster: Catalytic domain of components of vario... 61 2e-08
UniRef50_Q6ABX9 Cluster: Dihydrolipoyllysine-residue acetyltrans... 61 2e-08
UniRef50_P09062 Cluster: Lipoamide acyltransferase component of ... 61 2e-08
UniRef50_Q68FJ5 Cluster: MGC86218 protein; n=3; Tetrapoda|Rep: M... 61 3e-08
UniRef50_Q9FC63 Cluster: Putative acyltransferase; n=1; Streptom... 61 3e-08
UniRef50_A1ZE93 Cluster: Pyruvate dehydrogenase complex dihydrol... 61 3e-08
UniRef50_Q8D2N2 Cluster: AceF protein; n=1; Wigglesworthia gloss... 60 4e-08
UniRef50_Q9RPS3 Cluster: Dihydrolipoamide acyltransferase; n=3; ... 60 4e-08
UniRef50_Q1VYW1 Cluster: Dihydrolipoyllysine-residue acetyltrans... 60 4e-08
UniRef50_A6GG26 Cluster: Dihydrolipoyllysine-residue acetyltrans... 60 4e-08
UniRef50_Q98FT5 Cluster: Dihydrolipoamide acetyltransferase homo... 60 5e-08
UniRef50_Q4FS31 Cluster: Dihydrolipoyllysine acetyltransferase c... 60 5e-08
UniRef50_Q4L1A5 Cluster: Dihydrolipoamide acetyltransferase; n=2... 60 5e-08
UniRef50_A0JUQ7 Cluster: Catalytic domain of components of vario... 60 5e-08
UniRef50_P45118 Cluster: Dihydrolipoyllysine-residue acetyltrans... 60 5e-08
UniRef50_UPI000150A9DD Cluster: pyruvate dehydrogenase complex d... 60 7e-08
UniRef50_UPI0000E4A22B Cluster: PREDICTED: similar to pyruvate d... 60 7e-08
UniRef50_Q5WE92 Cluster: Acetoin dehydrogenase E2 component; n=1... 60 7e-08
UniRef50_Q1NYU2 Cluster: Dihydrolipoamide acyltransferase E2 com... 60 7e-08
UniRef50_Q0VRX7 Cluster: Pyruvate dehydrogenase, E2 component; n... 60 7e-08
UniRef50_A6W003 Cluster: Catalytic domain of components of vario... 60 7e-08
UniRef50_A4XEQ9 Cluster: Catalytic domain of components of vario... 60 7e-08
UniRef50_Q6L1M0 Cluster: Dihydrolipoamide acetyltransferase comp... 60 7e-08
UniRef50_P21883 Cluster: Dihydrolipoyllysine-residue acetyltrans... 60 7e-08
UniRef50_Q15U82 Cluster: Catalytic domain of components of vario... 59 9e-08
UniRef50_A5IXN4 Cluster: Dihydrolipoamide acetyltransferase comp... 59 9e-08
UniRef50_A4SZ52 Cluster: Catalytic domain of components of vario... 59 9e-08
UniRef50_Q4Q1F5 Cluster: Dihydrolipoamide acetyltransferase, put... 59 9e-08
UniRef50_O59816 Cluster: Dihydrolipoyllysine-residue acetyltrans... 59 9e-08
UniRef50_UPI0000D56122 Cluster: PREDICTED: similar to Lipoamide ... 59 1e-07
UniRef50_Q98PG1 Cluster: DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMP... 59 1e-07
UniRef50_A0H5V3 Cluster: Dihydrolipoamide S-succinyltransferase;... 59 1e-07
UniRef50_A2WKX8 Cluster: Putative uncharacterized protein; n=1; ... 59 1e-07
UniRef50_A0CWR1 Cluster: Chromosome undetermined scaffold_3, who... 59 1e-07
UniRef50_P10515 Cluster: Dihydrolipoyllysine-residue acetyltrans... 59 1e-07
UniRef50_P06959 Cluster: Dihydrolipoyllysine-residue acetyltrans... 59 1e-07
UniRef50_Q6A613 Cluster: Dihydrolipoamide acetyltransferase comp... 58 2e-07
UniRef50_Q0SGE5 Cluster: Dihydrolipoyllysine-residue succinyltra... 58 2e-07
UniRef50_A3WJV9 Cluster: Apha keto acid dehydrogenase complex, E... 58 2e-07
UniRef50_Q6F713 Cluster: Dihydrolipoamide S-acetyltransferase, E... 58 3e-07
UniRef50_Q2B858 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillu... 58 3e-07
UniRef50_A1SYC2 Cluster: Dihydrolipoamide dehydrogenase E3 compo... 58 3e-07
UniRef50_Q1EGH6 Cluster: Pyruvate dehydrogenase E2 subunit; n=1;... 58 3e-07
UniRef50_Q5Z123 Cluster: Putative branched-chain alpha-keto acid... 57 4e-07
UniRef50_Q3WAF9 Cluster: Biotin/lipoyl attachment:Catalytic doma... 57 4e-07
UniRef50_A6EAZ4 Cluster: Dihydrolipoyllysine-residue acetyltrans... 57 4e-07
UniRef50_Q55AS9 Cluster: Pyruvate dehydrogenase complex, compone... 57 4e-07
UniRef50_A7THD4 Cluster: Putative uncharacterized protein; n=1; ... 57 4e-07
UniRef50_Q5EIH5 Cluster: Dihydrolipoamide succinyltransferase co... 57 5e-07
UniRef50_A4XHV3 Cluster: Catalytic domain of components of vario... 57 5e-07
UniRef50_A0K281 Cluster: Catalytic domain of components of vario... 56 6e-07
UniRef50_Q9RXQ3 Cluster: Pyruvate dehydrogenase complex, dihydro... 56 8e-07
UniRef50_Q67RX4 Cluster: Putative uncharacterized protein; n=1; ... 56 8e-07
UniRef50_Q2JGZ2 Cluster: Dehydrogenase subunit; n=1; Frankia sp.... 56 8e-07
UniRef50_Q57Z16 Cluster: Dihydrolipoamide branched chain transac... 56 8e-07
UniRef50_Q63HZ8 Cluster: Lipoamide acyltransferase component of ... 56 1e-06
UniRef50_Q5P915 Cluster: Pyruvate dehydrogenase multienzyme comp... 55 1e-06
UniRef50_Q23VX7 Cluster: 2-oxo acid dehydrogenases acyltransfera... 55 1e-06
UniRef50_Q9M724 Cluster: Branched chain alpha-keto acid dehydrog... 55 2e-06
UniRef50_Q9VXY3 Cluster: CG5599-PA; n=4; Diptera|Rep: CG5599-PA ... 55 2e-06
UniRef50_Q0WQF7 Cluster: Dihydrolipoyllysine-residue acetyltrans... 55 2e-06
UniRef50_P12695 Cluster: Dihydrolipoyllysine-residue acetyltrans... 55 2e-06
UniRef50_P11182 Cluster: Lipoamide acyltransferase component of ... 55 2e-06
UniRef50_A0Z3Y6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 54 3e-06
UniRef50_Q4WQ92 Cluster: 2-oxo acid dehydrogenases acyltransfera... 54 3e-06
UniRef50_Q9PJZ6 Cluster: 2-oxo acid dehydrogenase, E2 component,... 54 3e-06
UniRef50_A5UU13 Cluster: Dihydrolipoyllysine-residue succinyltra... 54 3e-06
UniRef50_A5CVP1 Cluster: Pyruvate dehydrogenase complex E2 compo... 54 3e-06
UniRef50_A1T0M1 Cluster: Pyruvate dehydrogenase complex, E2 comp... 54 3e-06
UniRef50_A0PU60 Cluster: Dihydrolipoamide S-acetyltransferase E2... 54 3e-06
UniRef50_Q6FDE9 Cluster: Dihydrolipoamide acetyltransferase; n=3... 54 4e-06
UniRef50_Q4E6V7 Cluster: Putative uncharacterized protein; n=1; ... 54 4e-06
UniRef50_Q59638 Cluster: Dihydrolipoyllysine-residue acetyltrans... 54 4e-06
UniRef50_Q1LSX2 Cluster: Pyruvate dehydrogenase complex, E2 comp... 53 6e-06
UniRef50_Q13GQ6 Cluster: Dihydrolipoamide acyltransferase (E2) c... 53 6e-06
UniRef50_A0G738 Cluster: Catalytic domain of components of vario... 53 6e-06
UniRef50_A7SJI4 Cluster: Predicted protein; n=2; Nematostella ve... 53 6e-06
UniRef50_A3SYT7 Cluster: Acetoin dehydrogenase E2 component; n=2... 53 8e-06
UniRef50_Q54TR7 Cluster: Dihydrolipoyl transacylase; n=1; Dictyo... 53 8e-06
UniRef50_P10802 Cluster: Dihydrolipoyllysine-residue acetyltrans... 53 8e-06
UniRef50_A3CMZ5 Cluster: Dihydrolipoamide acetyl transferase, E2... 52 1e-05
UniRef50_Q2UJZ9 Cluster: Dihydrolipoamide transacylase; n=9; Eur... 52 1e-05
UniRef50_Q8EVQ0 Cluster: Dihydrolipoamide acetyltransferase of p... 52 1e-05
UniRef50_Q6C806 Cluster: Similar to tr|Q9VXY3 Drosophila melanog... 52 2e-05
UniRef50_Q0UN70 Cluster: Putative uncharacterized protein; n=1; ... 51 2e-05
UniRef50_Q9R9N3 Cluster: Dihydrolipoyllysine-residue acetyltrans... 51 2e-05
UniRef50_Q1V1J3 Cluster: Dihydrolipoamide S-acetyltransferase; n... 51 3e-05
UniRef50_A6PJ30 Cluster: Catalytic domain of components of vario... 51 3e-05
UniRef50_A1KCD0 Cluster: Putative uncharacterized protein; n=1; ... 51 3e-05
UniRef50_Q14Q97 Cluster: Putative uncharacterized protein; n=1; ... 50 4e-05
UniRef50_Q7RS62 Cluster: Plasmodium vivax PV1H14105_P; n=8; Plas... 50 4e-05
UniRef50_Q7NHG8 Cluster: Dihydrolipoamide S-acetyltransferase; n... 50 5e-05
UniRef50_UPI0000DB75B7 Cluster: PREDICTED: similar to Lipoamide ... 50 7e-05
UniRef50_UPI000038D51F Cluster: COG0508: Pyruvate/2-oxoglutarate... 50 7e-05
UniRef50_Q7MB23 Cluster: Similar to peptide synthetase. Putative... 50 7e-05
UniRef50_A1RJV4 Cluster: Catalytic domain of components of vario... 50 7e-05
UniRef50_P75392 Cluster: Dihydrolipoyllysine-residue acetyltrans... 50 7e-05
UniRef50_A0J2S5 Cluster: Catalytic domain of components of vario... 49 1e-04
UniRef50_Q9SQI8 Cluster: Dihydrolipoamide S-acetyltransferase; n... 49 1e-04
UniRef50_A6PBA2 Cluster: Catalytic domain of components of vario... 48 2e-04
UniRef50_A0JS87 Cluster: Catalytic domain of components of vario... 48 2e-04
UniRef50_Q7SH25 Cluster: Putative uncharacterized protein NCU027... 48 2e-04
UniRef50_Q057U1 Cluster: Pyruvate dehydrogenase E2 component; n=... 48 2e-04
UniRef50_A7BE99 Cluster: Putative uncharacterized protein; n=1; ... 48 3e-04
UniRef50_A4BTC4 Cluster: Dihydrolipoamide acetyltransferase; n=2... 47 4e-04
UniRef50_A0D1R4 Cluster: Chromosome undetermined scaffold_34, wh... 47 4e-04
UniRef50_Q7NB00 Cluster: AceF; n=1; Mycoplasma gallisepticum|Rep... 46 7e-04
UniRef50_Q7RFX9 Cluster: Putative dihydrolipoamide S-acetyltrans... 46 0.001
UniRef50_Q5VGY2 Cluster: Dihydrolipoamide S-acetyltransferase; n... 46 0.001
UniRef50_Q5HKM0 Cluster: Acetoin dehydrogenase, E2 component, di... 45 0.002
UniRef50_A4RMY6 Cluster: Putative uncharacterized protein; n=1; ... 45 0.002
UniRef50_Q8D6Q5 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 44 0.003
UniRef50_Q0A5F2 Cluster: Catalytic domain of components of vario... 44 0.003
UniRef50_UPI0000E48C7F Cluster: PREDICTED: similar to transacyla... 44 0.004
UniRef50_Q6AIE3 Cluster: Probable pyruvate dehydrogenase, E2 com... 44 0.005
UniRef50_A1FTV4 Cluster: Catalytic domain of components of vario... 44 0.005
UniRef50_A7Q7E8 Cluster: Chromosome chr18 scaffold_59, whole gen... 44 0.005
UniRef50_A5V538 Cluster: Catalytic domain of components of vario... 43 0.008
UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 42 0.011
UniRef50_A6FIQ1 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 42 0.011
UniRef50_Q59658 Cluster: Dihydrolipoamide acetyltransferase; n=3... 42 0.019
UniRef50_A0Z5N6 Cluster: Pyruvate dehydrogenase complex, E2 comp... 42 0.019
UniRef50_Q12FH2 Cluster: Catalytic domain of components of vario... 41 0.025
UniRef50_A6Q9K5 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 41 0.025
UniRef50_A3BC27 Cluster: Putative uncharacterized protein; n=2; ... 41 0.025
UniRef50_Q89AQ9 Cluster: Dihydrolipoyllysine-residue acetyltrans... 41 0.025
UniRef50_Q1QQR8 Cluster: Putative uncharacterized protein; n=1; ... 41 0.033
UniRef50_Q5ZV80 Cluster: Dihydrolipoamide acetyltransferase; n=5... 40 0.044
UniRef50_A6Q8W6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 40 0.044
UniRef50_A1UBW5 Cluster: Catalytic domain of components of vario... 40 0.044
UniRef50_A5KCF0 Cluster: Dihydrolipoamide acetyltransferase, put... 40 0.044
UniRef50_Q83DQ8 Cluster: Dehydrogenase, E2 component, acyltransf... 40 0.058
UniRef50_Q01VQ8 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni... 40 0.058
UniRef50_Q8PQ85 Cluster: Dihydrolipoamide acyltransferase; n=7; ... 40 0.076
UniRef50_Q9SIT8 Cluster: Putative uncharacterized protein At2g13... 39 0.10
UniRef50_A6RRC1 Cluster: Putative uncharacterized protein; n=2; ... 39 0.10
UniRef50_Q8NRC3 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 39 0.13
UniRef50_Q1D6S2 Cluster: 2-oxo acid dehydrogenase acyltransferas... 38 0.18
UniRef50_Q9K3H2 Cluster: Putative acyltransferase; n=1; Streptom... 38 0.23
UniRef50_Q7TQ85 Cluster: Ac1164; n=1; Rattus norvegicus|Rep: Ac1... 38 0.31
UniRef50_Q7VDH5 Cluster: Dihydrolipoamide S-acetyltransferase; n... 37 0.41
UniRef50_Q3W1D8 Cluster: Catalytic domain of components of vario... 37 0.41
UniRef50_A4M1P4 Cluster: Biotin/lipoyl attachment domain-contain... 37 0.41
UniRef50_Q6XYS6 Cluster: Dihydrolipoamide acetyltransferase; n=1... 37 0.54
UniRef50_Q14PE3 Cluster: Hypothetical dihydrolipoamide acetyltra... 37 0.54
UniRef50_A4AIF6 Cluster: Dihydrolipoamide acetyltransferase; n=1... 37 0.54
UniRef50_Q3LVF5 Cluster: TO119-1rc; n=1; Taraxacum officinale|Re... 37 0.54
UniRef50_A7MGN4 Cluster: Putative uncharacterized protein; n=2; ... 36 1.2
UniRef50_Q5AGX7 Cluster: Putative uncharacterized protein; n=1; ... 35 1.6
UniRef50_Q6BX57 Cluster: Debaryomyces hansenii chromosome B of s... 35 2.2
UniRef50_UPI000038CE95 Cluster: COG0508: Pyruvate/2-oxoglutarate... 34 3.8
UniRef50_Q64X52 Cluster: Probable DNA polymerase III epsilon cha... 34 3.8
UniRef50_A7AT28 Cluster: Lipoamide acyltransferase component of ... 34 3.8
UniRef50_Q3ITY3 Cluster: Putative uncharacterized protein; n=1; ... 34 3.8
UniRef50_UPI0000660924 Cluster: UPI0000660924 related cluster; n... 33 5.0
UniRef50_Q9KBS7 Cluster: BH1847 protein; n=1; Bacillus haloduran... 33 5.0
UniRef50_Q2SCI9 Cluster: Uncharacterized protein, possibly invol... 33 5.0
UniRef50_Q4FBE8 Cluster: Putative uncharacterized protein; n=3; ... 33 5.0
UniRef50_Q1CXL3 Cluster: 2-oxo acid dehydrogenases acyltransfera... 33 5.0
UniRef50_A6LCJ6 Cluster: Putative uncharacterized protein; n=1; ... 33 6.6
UniRef50_Q2Z173 Cluster: Putative uncharacterized protein; n=1; ... 33 6.6
UniRef50_A2EQ26 Cluster: Surface antigen BspA-like; n=3; Trichom... 33 6.6
UniRef50_Q82EY7 Cluster: Putative integrin-like protein; n=1; St... 33 8.8
UniRef50_Q7UVC8 Cluster: Dihydrolipoyl dehydrogenase; n=3; Bacte... 33 8.8
UniRef50_A0V4D4 Cluster: Putative uncharacterized protein; n=1; ... 33 8.8
UniRef50_Q87SG6 Cluster: UDP-N-acetylmuramoylalanine--D-glutamat... 33 8.8
>UniRef50_P0AFG7 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=24; Enterobacteriaceae|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Escherichia coli O157:H7
Length = 405
Score = 180 bits (438), Expect = 3e-44
Identities = 85/85 (100%), Positives = 85/85 (100%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS
Sbjct: 196 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 255
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
IDGDDVVYHNYFDVSMAVSTPRGLV
Sbjct: 256 IDGDDVVYHNYFDVSMAVSTPRGLV 280
Score = 173 bits (421), Expect = 3e-42
Identities = 84/85 (98%), Positives = 84/85 (98%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TPVLRDVDTLGMADIEKKIKELAVKG DGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP
Sbjct: 281 TPVLRDVDTLGMADIEKKIKELAVKGRDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 340
Query: 435 PQSAILGMHAIKDRPMAVNGQVEIL 509
PQSAILGMHAIKDRPMAVNGQVEIL
Sbjct: 341 PQSAILGMHAIKDRPMAVNGQVEIL 365
Score = 85.0 bits (201), Expect = 2e-15
Identities = 40/40 (100%), Positives = 40/40 (100%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV
Sbjct: 366 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 405
>UniRef50_Q8DFQ0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dihydrolipoamide acyltransferase component;
n=17; Bacteria|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide acyltransferase
component - Vibrio vulnificus
Length = 402
Score = 171 bits (417), Expect = 1e-41
Identities = 78/85 (91%), Positives = 82/85 (96%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
KNSTAMLTTFNEVNMKPIMDLRKQYG+ FE RHGIRLGFMSFYVKAV EALKRYPE+NAS
Sbjct: 193 KNSTAMLTTFNEVNMKPIMDLRKQYGDQFEARHGIRLGFMSFYVKAVTEALKRYPEINAS 252
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
IDGDD+VYHNYFD+SMAVSTPRGLV
Sbjct: 253 IDGDDIVYHNYFDISMAVSTPRGLV 277
Score = 152 bits (368), Expect = 9e-36
Identities = 71/85 (83%), Positives = 79/85 (92%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TPVL+D DTLG AD+EK IKELA+KG DGKLTV++L GGNFTITNGGVFGSLMSTPIINP
Sbjct: 278 TPVLKDCDTLGFADVEKGIKELAIKGRDGKLTVDELIGGNFTITNGGVFGSLMSTPIINP 337
Query: 435 PQSAILGMHAIKDRPMAVNGQVEIL 509
PQSAILGMH I+DRPMAV+G+VEIL
Sbjct: 338 PQSAILGMHKIQDRPMAVDGKVEIL 362
Score = 82.6 bits (195), Expect = 8e-15
Identities = 38/40 (95%), Positives = 39/40 (97%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
PMMYLALSYDHRLIDGRESVGFLVT+KELLEDP RLLLDV
Sbjct: 363 PMMYLALSYDHRLIDGRESVGFLVTVKELLEDPARLLLDV 402
>UniRef50_Q89AJ6 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=15; Proteobacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Buchnera aphidicola subsp. Baizongia pistaciae
Length = 410
Score = 140 bits (339), Expect = 3e-32
Identities = 59/85 (69%), Positives = 79/85 (92%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
KN+TA LTTFNEVNM+ I++LR++YGE F+++HGI+LG MSFYVKAV+EALK +PE+NAS
Sbjct: 201 KNNTASLTTFNEVNMQSILNLRRKYGELFKQKHGIKLGLMSFYVKAVIEALKIFPEINAS 260
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
ID D+++Y+NYFD+S+A+STPRGLV
Sbjct: 261 IDNDEIIYYNYFDISIAISTPRGLV 285
Score = 122 bits (293), Expect = 1e-26
Identities = 55/84 (65%), Positives = 69/84 (82%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TPVL++ D + MA+IE KIK+ + KG + KLT++DL GGNFTITNGGVFGSL STP+INP
Sbjct: 286 TPVLKNADLMSMAEIEIKIKDFSEKGKNSKLTIDDLIGGNFTITNGGVFGSLFSTPLINP 345
Query: 435 PQSAILGMHAIKDRPMAVNGQVEI 506
PQSAILGMHAI RP+ V+ +E+
Sbjct: 346 PQSAILGMHAIHKRPVIVDENIEV 369
Score = 68.1 bits (159), Expect = 2e-10
Identities = 30/40 (75%), Positives = 37/40 (92%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
PMMYLALSYDHRLIDG+ESVGFL+ IKE LED +R++L++
Sbjct: 371 PMMYLALSYDHRLIDGKESVGFLLKIKEFLEDFSRIVLNI 410
>UniRef50_P57389 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=2; Enterobacteriaceae|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Buchnera aphidicola subsp. Acyrthosiphon pisum
(Acyrthosiphon pisumsymbiotic bacterium)
Length = 420
Score = 134 bits (325), Expect = 1e-30
Identities = 58/85 (68%), Positives = 75/85 (88%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TPV+R+ DT+ MA+IEKKIK+ ++KG K+ +++L GGNFTITNGGVFGSLMSTPIINP
Sbjct: 296 TPVIRNADTMTMAEIEKKIKDFSIKGLQNKINIKELMGGNFTITNGGVFGSLMSTPIINP 355
Query: 435 PQSAILGMHAIKDRPMAVNGQVEIL 509
PQ+AILGMH I++RP+ VNGQ++IL
Sbjct: 356 PQTAILGMHVIQERPVVVNGQIKIL 380
Score = 133 bits (322), Expect = 3e-30
Identities = 57/85 (67%), Positives = 76/85 (89%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
KN+TAMLTTF+EVNMKPI+ LRK+YGE FEK+H +R+GFMSF+VKAV++ALK +PE+NA
Sbjct: 211 KNNTAMLTTFHEVNMKPIILLRKKYGEDFEKKHNVRIGFMSFFVKAVIQALKNFPEINAY 270
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
ID D+V++ FD+S+A+STPRGL+
Sbjct: 271 IDQTDIVFYKNFDISIAISTPRGLI 295
Score = 68.5 bits (160), Expect = 1e-10
Identities = 30/40 (75%), Positives = 35/40 (87%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
PMMYLALSYDHRLIDG+ESVGFL+ IK +LED R+ +DV
Sbjct: 381 PMMYLALSYDHRLIDGKESVGFLINIKNILEDFNRIAIDV 420
>UniRef50_Q63TQ8 Cluster: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex; n=42;
Proteobacteria|Rep: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex -
Burkholderia pseudomallei (Pseudomonas pseudomallei)
Length = 425
Score = 132 bits (319), Expect = 8e-30
Identities = 56/85 (65%), Positives = 73/85 (85%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+ + A+LTTFNEVNM+P+MDLR +Y + FEK HG++LGFMSF+VKA V ALK++P VNAS
Sbjct: 216 QQTNAILTTFNEVNMQPVMDLRAKYKDKFEKEHGVKLGFMSFFVKAAVHALKKFPLVNAS 275
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
IDG+D+VYH YFD+ +AV +PRGLV
Sbjct: 276 IDGNDIVYHGYFDIGIAVGSPRGLV 300
Score = 121 bits (292), Expect = 1e-26
Identities = 53/83 (63%), Positives = 69/83 (83%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
P+LR+ D L +A+IEKKI E K DGKL++E++TGG F+I+NGGVFGS++STPIINPP
Sbjct: 302 PILRNADQLSLAEIEKKIAEFGQKAKDGKLSIEEMTGGTFSISNGGVFGSMLSTPIINPP 361
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
QSAILG+HA K+RP+ NGQ+ I
Sbjct: 362 QSAILGVHATKERPVVENGQIVI 384
Score = 61.7 bits (143), Expect = 2e-08
Identities = 28/40 (70%), Positives = 34/40 (85%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
P+ YLALSYDHR+IDGRE+V LV +K+ LEDP RLLLD+
Sbjct: 386 PINYLALSYDHRIIDGREAVLSLVAMKDALEDPARLLLDL 425
>UniRef50_A4BP63 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=4;
Bacteria|Rep: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase -
Nitrococcus mobilis Nb-231
Length = 443
Score = 129 bits (312), Expect = 6e-29
Identities = 56/85 (65%), Positives = 71/85 (83%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+ +TAMLTTFNE NM+PIM LR +Y E FE+ HGI+LG MSF+VK V+EALKR+P VNAS
Sbjct: 234 QQNTAMLTTFNECNMQPIMSLRNRYKERFERYHGIKLGIMSFFVKTVIEALKRFPAVNAS 293
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
IDG D++YH Y+D+ +AVST RGL+
Sbjct: 294 IDGKDIIYHGYYDIGIAVSTERGLL 318
Score = 111 bits (268), Expect = 1e-23
Identities = 49/83 (59%), Positives = 63/83 (75%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PVLRD D LG A+IE+ I + + + K+ +++LTGG FTITNGG+FGSLMSTPI+NPP
Sbjct: 320 PVLRDADQLGFAEIEQAIADFGRRARESKIHIDELTGGTFTITNGGIFGSLMSTPILNPP 379
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
QS ILGMH I+DRP+ N V +
Sbjct: 380 QSGILGMHRIQDRPVVENAAVTV 402
Score = 76.6 bits (180), Expect = 5e-13
Identities = 35/40 (87%), Positives = 39/40 (97%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
PMMYLALSYDHR+IDGRE+V FLVTIKELLEDP+RLLL+V
Sbjct: 404 PMMYLALSYDHRIIDGREAVQFLVTIKELLEDPSRLLLEV 443
>UniRef50_Q82SG4 Cluster: SucB; dihydrolipoamide succinyltransferase
(Component of 2- oxoglutarate dehydrogenase complex)
protein; n=4; Bacteria|Rep: SucB; dihydrolipoamide
succinyltransferase (Component of 2- oxoglutarate
dehydrogenase complex) protein - Nitrosomonas europaea
Length = 425
Score = 128 bits (309), Expect = 1e-28
Identities = 53/85 (62%), Positives = 76/85 (89%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+++ A+LTTFNEVNM+ IMDLR +Y ++FEK HGI+LGF SF+VKAVV ALK++P +NAS
Sbjct: 216 QSTAAILTTFNEVNMQAIMDLRARYKDSFEKEHGIKLGFTSFFVKAVVAALKKFPIINAS 275
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
+DG+D++YH+Y+D+ +AV++PRGLV
Sbjct: 276 VDGNDIIYHDYYDIGIAVASPRGLV 300
Score = 119 bits (287), Expect = 6e-26
Identities = 54/83 (65%), Positives = 68/83 (81%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
P++RD D L A IEK+I +LA + +GKLT+E+LTGG F+ITNGGVFGS++STPIINPP
Sbjct: 302 PIIRDADKLTFAGIEKQIADLARRAQEGKLTLEELTGGTFSITNGGVFGSMLSTPIINPP 361
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
QSAILG+HA K RP+ NGQ+ I
Sbjct: 362 QSAILGIHATKQRPVVENGQIVI 384
Score = 51.6 bits (118), Expect = 2e-05
Identities = 25/39 (64%), Positives = 29/39 (74%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
P+ YLALSYDHR+IDGRE+V LV IKE LE P L +
Sbjct: 386 PINYLALSYDHRIIDGREAVLSLVAIKEALEYPVSPLFE 424
>UniRef50_A6DL93 Cluster: Dihydrolipoamide acetyltransferase; n=1;
Lentisphaera araneosa HTCC2155|Rep: Dihydrolipoamide
acetyltransferase - Lentisphaera araneosa HTCC2155
Length = 415
Score = 122 bits (294), Expect = 8e-27
Identities = 56/83 (67%), Positives = 69/83 (83%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+RD D L + IE+KI+ELA+KG D LT E++TGG FTITNGG FGS++STPI+N P
Sbjct: 292 PVIRDCDQLNFSGIERKIRELALKGRDMDLTPEEMTGGTFTITNGGTFGSMLSTPILNRP 351
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
QSAILGMH I +RP+AVNGQVE+
Sbjct: 352 QSAILGMHNIVERPVAVNGQVEV 374
Score = 102 bits (245), Expect = 7e-21
Identities = 42/85 (49%), Positives = 65/85 (76%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+ A+L+TFNE++M +M+LRKQ+ + F+ +H I LGFMSF+ KA ALK +P +NA
Sbjct: 206 QQEAAILSTFNEIDMSAVMNLRKQHKDEFKDKHEIGLGFMSFFTKATAIALKEFPIMNAQ 265
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
+DG+ ++YH++ D+ +AVSTP+GLV
Sbjct: 266 VDGNSIIYHDFVDMGIAVSTPKGLV 290
Score = 64.9 bits (151), Expect = 2e-09
Identities = 28/40 (70%), Positives = 36/40 (90%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
P+MYLA+SYDHR+IDG ++V FLV IK LLEDPTR+LL++
Sbjct: 376 PIMYLAVSYDHRIIDGSDAVRFLVKIKTLLEDPTRMLLEL 415
>UniRef50_A0M5Y1 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=7; Flavobacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Gramella forsetii (strain KT0803)
Length = 438
Score = 121 bits (292), Expect = 1e-26
Identities = 52/83 (62%), Positives = 69/83 (83%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R+ + L +E ++K LA+K DGK+TV+++TGG FTITNGGVFGS++STPIINPP
Sbjct: 307 PVIRNAENLSFRGVESEVKRLAIKARDGKITVDEMTGGTFTITNGGVFGSMLSTPIINPP 366
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
QSAILGMH I +RP+A++G VEI
Sbjct: 367 QSAILGMHNIVERPVAIDGHVEI 389
Score = 111 bits (268), Expect = 1e-23
Identities = 50/84 (59%), Positives = 65/84 (77%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
KN TAMLTTFNEV+M PI +LRK+Y E F+ +HG+ LGFMSF+ AV+ AL YP VN+
Sbjct: 221 KNDTAMLTTFNEVDMSPIFELRKKYKEEFKDKHGVSLGFMSFFTLAVIRALDEYPAVNSM 280
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGL 252
IDGD + ++Y D+S+AVS P+GL
Sbjct: 281 IDGDYQISYDYKDISIAVSGPKGL 304
Score = 67.3 bits (157), Expect = 3e-10
Identities = 29/39 (74%), Positives = 35/39 (89%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
P+MY+ALSYDHR+IDG+ESVGFLV IKE LE+P LL+D
Sbjct: 391 PIMYVALSYDHRIIDGKESVGFLVAIKEALENPEELLMD 429
>UniRef50_Q057P2 Cluster: 2-oxoglutarate dehydrogenase E2 component;
n=1; Buchnera aphidicola str. Cc (Cinara cedri)|Rep:
2-oxoglutarate dehydrogenase E2 component - Buchnera
aphidicola subsp. Cinara cedri
Length = 398
Score = 120 bits (290), Expect = 3e-26
Identities = 48/83 (57%), Positives = 73/83 (87%)
Frame = +1
Query: 7 STAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID 186
+TAMLTTFNEVNM+PI+ +R +Y + FE ++ +LGFMSFYVK+V +ALK++PE+NASI+
Sbjct: 191 NTAMLTTFNEVNMQPIISIRNKYKDIFENKYKSKLGFMSFYVKSVTQALKKFPEINASIE 250
Query: 187 GDDVVYHNYFDVSMAVSTPRGLV 255
+++YH+Y+D+++A+STPRGL+
Sbjct: 251 KKNIIYHDYYDINIAISTPRGLI 273
Score = 116 bits (280), Expect = 4e-25
Identities = 55/85 (64%), Positives = 65/85 (76%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP+L++ D L + +IEKKIK + G GKL EDL G FTITNGGVFGSLMSTPIINP
Sbjct: 274 TPILKNTDNLSIYEIEKKIKSFVLLGEQGKLKFEDLEAGTFTITNGGVFGSLMSTPIINP 333
Query: 435 PQSAILGMHAIKDRPMAVNGQVEIL 509
PQ AILGMH IK RP+ VN +++IL
Sbjct: 334 PQVAILGMHHIKKRPIVVNKKIKIL 358
Score = 58.4 bits (135), Expect = 2e-07
Identities = 24/40 (60%), Positives = 35/40 (87%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
PMMYLALSYDH+LIDG++++ FL IK++LED +R +L++
Sbjct: 359 PMMYLALSYDHQLIDGKQAIQFLNYIKDILEDISRFILEI 398
>UniRef50_Q1E5N3 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial; n=8; Dikarya|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex,
mitochondrial - Coccidioides immitis
Length = 484
Score = 118 bits (284), Expect = 1e-25
Identities = 53/84 (63%), Positives = 68/84 (80%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TPV+R+V+ + + IEK I +L K D KLT+ED+ GG FTI+NGGVFGSLM TPIIN
Sbjct: 361 TPVVRNVENMDLTTIEKAIADLGQKARDNKLTIEDMAGGTFTISNGGVFGSLMGTPIINL 420
Query: 435 PQSAILGMHAIKDRPMAVNGQVEI 506
PQ+ +LG+HAIK+RP+AVNG+VEI
Sbjct: 421 PQTGVLGLHAIKNRPVAVNGKVEI 444
Score = 92.7 bits (220), Expect = 8e-18
Identities = 46/89 (51%), Positives = 63/89 (70%), Gaps = 4/89 (4%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+N+ A LTTFNEV+M +M+ RK Y E K+ GI+LGFMS + +A V A+K P VNAS
Sbjct: 272 QNTAASLTTFNEVDMSSLMEFRKLYKEDILKKTGIKLGFMSAFARACVLAMKEVPAVNAS 331
Query: 181 ID----GDDVVYHNYFDVSMAVSTPRGLV 255
I+ GD +VY +Y D+S+AV+T +GLV
Sbjct: 332 IEGPNGGDTIVYRDYVDISVAVATEKGLV 360
Score = 66.1 bits (154), Expect = 8e-10
Identities = 28/38 (73%), Positives = 34/38 (89%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
PMMYLAL+YDHRL+DGRE+V FLV +KE +EDP R+LL
Sbjct: 446 PMMYLALTYDHRLLDGREAVTFLVRVKEFIEDPRRMLL 483
>UniRef50_Q39RZ0 Cluster: Dihydrolipoamide succinyltransferase; n=3;
Geobacter|Rep: Dihydrolipoamide succinyltransferase -
Geobacter metallireducens (strain GS-15 / ATCC 53774 /
DSM 7210)
Length = 418
Score = 118 bits (283), Expect = 2e-25
Identities = 49/85 (57%), Positives = 68/85 (80%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+ TAMLTTFNE ++ +M+LRK+Y E F+K+HG+ LGFMSF+VKA VEALK YP VN S
Sbjct: 209 RQQTAMLTTFNEADLGRVMELRKKYKEHFQKKHGVSLGFMSFFVKACVEALKEYPAVNGS 268
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
I+GDD+V+H+Y+ + +A+ +GLV
Sbjct: 269 IEGDDIVFHHYYHIGIAIGAEKGLV 293
Score = 103 bits (247), Expect = 4e-21
Identities = 47/83 (56%), Positives = 61/83 (73%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PVLRD D L A+IE I A K +L + DL GG FTI+NGGV+GSL+STPI+NPP
Sbjct: 295 PVLRDADRLSFAEIETTIAGFAEKTKANRLELSDLQGGTFTISNGGVYGSLLSTPILNPP 354
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
QS +LGMHA+++RP+ +GQ+ I
Sbjct: 355 QSGVLGMHAVQERPVVRDGQIVI 377
Score = 63.7 bits (148), Expect = 4e-09
Identities = 27/39 (69%), Positives = 33/39 (84%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
PMMYLALSYDHR+IDGRE+VGFL +KE +E+P L L+
Sbjct: 379 PMMYLALSYDHRIIDGREAVGFLKKVKEYVEEPEELFLE 417
>UniRef50_Q6FYD4 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=79; Bacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Bartonella quintana (Rochalimaea quintana)
Length = 410
Score = 118 bits (283), Expect = 2e-25
Identities = 51/85 (60%), Positives = 66/85 (77%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+N+ AMLTTFNEV+M +MDLRK+Y + FEK+HG++LGFM F+ KAV ALK +P VNA
Sbjct: 201 QNTAAMLTTFNEVDMSAVMDLRKRYKDLFEKKHGVKLGFMGFFTKAVCHALKEFPTVNAE 260
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
IDG D+VY NY + +AV T +GLV
Sbjct: 261 IDGTDIVYKNYVNAGIAVGTDKGLV 285
Score = 114 bits (274), Expect = 2e-24
Identities = 53/83 (63%), Positives = 63/83 (75%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+RD D + +A+IEK+I L DGKL V D+ GG FTITNGGV+GSLMSTPI+N P
Sbjct: 287 PVVRDADQMSLAEIEKEISRLGRLARDGKLAVSDMQGGTFTITNGGVYGSLMSTPILNAP 346
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
QS ILGMHAIK+R M V GQ+ I
Sbjct: 347 QSGILGMHAIKERAMVVGGQIII 369
Score = 67.7 bits (158), Expect = 3e-10
Identities = 29/40 (72%), Positives = 36/40 (90%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
PMMYLALSYDHR++DG+E+V FLV +KE LEDP RL+LD+
Sbjct: 371 PMMYLALSYDHRIVDGQEAVTFLVRVKESLEDPERLVLDL 410
>UniRef50_A5EW59 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=1;
Dichelobacter nodosus VCS1703A|Rep: 2-oxoglutarate
dehydrogenase, E2 component, dihydrolipoamide
succinyltransferase - Dichelobacter nodosus (strain
VCS1703A)
Length = 341
Score = 117 bits (282), Expect = 2e-25
Identities = 52/83 (62%), Positives = 66/83 (79%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
P+LR+ +TL ADIE++IK A K DG L++E+++ G FTITNGG FGS++STPI+NPP
Sbjct: 218 PILRNAETLSFADIERQIKIFAEKAADGSLSLEEISDGTFTITNGGTFGSMLSTPILNPP 277
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
QSAILGMHAI DRPM NG + I
Sbjct: 278 QSAILGMHAIVDRPMVENGAIVI 300
Score = 107 bits (257), Expect = 3e-22
Identities = 45/85 (52%), Positives = 67/85 (78%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+ +TAMLTTFNE+NM+ +M+ R + F K++G++LG MSF+V+A V AL+++P +NA
Sbjct: 132 QQTTAMLTTFNEINMQAVMNYRHDFQNDFVKKYGVKLGLMSFFVRAAVAALRQFPVINAM 191
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
IDGDDVVY Y ++ +AV++PRGLV
Sbjct: 192 IDGDDVVYRRYCNIGIAVASPRGLV 216
Score = 65.3 bits (152), Expect = 1e-09
Identities = 30/40 (75%), Positives = 35/40 (87%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
P+MY+ALSYDHRLIDGRE+V FL TIK +LE P RLLLD+
Sbjct: 302 PVMYVALSYDHRLIDGREAVLFLKTIKNMLEAPARLLLDL 341
>UniRef50_Q4UKI7 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=135; root|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Rickettsia felis (Rickettsia azadi)
Length = 401
Score = 117 bits (282), Expect = 2e-25
Identities = 51/85 (60%), Positives = 68/85 (80%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+N+ A+LTTFNE++M ++ LR QY E FEK+H ++LGFMSF+VKA +EALK P VNA
Sbjct: 192 QNTAAILTTFNEIDMSKVIALRNQYKEEFEKKHLVKLGFMSFFVKATIEALKLIPSVNAE 251
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
IDGDD+VY NY+D+ +AV T +GLV
Sbjct: 252 IDGDDLVYKNYYDIGVAVGTEQGLV 276
Score = 109 bits (263), Expect = 5e-23
Identities = 47/83 (56%), Positives = 67/83 (80%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+RD D +G A++EK I LA K +GKL++ DL+GG F+I+NGGV+GSL+STPIINPP
Sbjct: 278 PVVRDADKMGFAEVEKAIGTLAKKAREGKLSMADLSGGTFSISNGGVYGSLLSTPIINPP 337
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
QS ILG+H ++R + ++G++EI
Sbjct: 338 QSGILGLHKTEERAVVIDGKIEI 360
Score = 66.1 bits (154), Expect = 8e-10
Identities = 28/40 (70%), Positives = 36/40 (90%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
PMMY+ALSYDHR+IDG+E V FLV IKEL+E+P +LLL++
Sbjct: 362 PMMYIALSYDHRIIDGKEGVSFLVKIKELIENPEKLLLNL 401
>UniRef50_A6SDP7 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 370
Score = 116 bits (279), Expect = 5e-25
Identities = 51/84 (60%), Positives = 67/84 (79%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TPV+R+ +++ + IEK I +L K D KLT+ED+ GG FTI+NGGVFGSLM TPIIN
Sbjct: 248 TPVVRNTESMDLVGIEKTIADLGKKARDNKLTIEDMAGGTFTISNGGVFGSLMGTPIINL 307
Query: 435 PQSAILGMHAIKDRPMAVNGQVEI 506
PQ+A+LG+HAIKD+P+ VNGQ+ I
Sbjct: 308 PQTAVLGLHAIKDKPVVVNGQIVI 331
Score = 65.7 bits (153), Expect = 1e-09
Identities = 28/38 (73%), Positives = 34/38 (89%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
PMMYLAL+YDHRL+DGRE+V FLV +KE +EDP R+LL
Sbjct: 333 PMMYLALTYDHRLLDGREAVQFLVKVKEYIEDPRRMLL 370
Score = 39.1 bits (87), Expect = 0.10
Identities = 19/37 (51%), Positives = 27/37 (72%), Gaps = 4/37 (10%)
Frame = +1
Query: 157 RYPEVNASIDG----DDVVYHNYFDVSMAVSTPRGLV 255
R E+NASI+G D +VY +Y D+S+AV+T +GLV
Sbjct: 211 RIAELNASIEGPNGGDTIVYRDYVDISVAVATEKGLV 247
>UniRef50_P19262 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial precursor; n=21;
Ascomycota|Rep: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial precursor -
Saccharomyces cerevisiae (Baker's yeast)
Length = 463
Score = 116 bits (278), Expect = 7e-25
Identities = 50/82 (60%), Positives = 67/82 (81%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TPV+R+ ++L + DIE +I L+ K DGKLT+ED+TGG FTI+NGGVFGSL TPIIN
Sbjct: 340 TPVVRNAESLSVLDIENEIVRLSHKARDGKLTLEDMTGGTFTISNGGVFGSLYGTPIINS 399
Query: 435 PQSAILGMHAIKDRPMAVNGQV 500
PQ+A+LG+H +K+RP+ VNGQ+
Sbjct: 400 PQTAVLGLHGVKERPVTVNGQI 421
Score = 92.3 bits (219), Expect = 1e-17
Identities = 41/85 (48%), Positives = 59/85 (69%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+N+ A LTTFNEV+M +M++RK Y + K+ G + GFM + KA A K P VN +
Sbjct: 255 QNTAASLTTFNEVDMSALMEMRKLYKDEIIKKTGTKFGFMGLFSKACTLAAKDIPAVNGA 314
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
I+GD +VY +Y D+S+AV+TP+GLV
Sbjct: 315 IEGDQIVYRDYTDISVAVATPKGLV 339
Score = 66.5 bits (155), Expect = 6e-10
Identities = 28/38 (73%), Positives = 35/38 (92%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
PMMYLAL+YDHRL+DGRE+V FL T+KEL+EDP ++LL
Sbjct: 425 PMMYLALTYDHRLLDGREAVTFLKTVKELIEDPRKMLL 462
>UniRef50_Q98ED1 Cluster: Dihydrolipoamide succinyl transferase;
n=8; Bacteria|Rep: Dihydrolipoamide succinyl transferase
- Rhizobium loti (Mesorhizobium loti)
Length = 424
Score = 114 bits (274), Expect = 2e-24
Identities = 51/83 (61%), Positives = 65/83 (78%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+RD D + +A+IEK+I L + DGKL+V D+ GG FTI+NGGV+GSLMSTPI+N P
Sbjct: 301 PVVRDADQMSIAEIEKEIGRLGIAARDGKLSVADMQGGTFTISNGGVYGSLMSTPILNAP 360
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
QS ILGMH I+DRP+ V GQ+ I
Sbjct: 361 QSGILGMHKIQDRPVVVGGQIVI 383
Score = 107 bits (258), Expect = 2e-22
Identities = 47/85 (55%), Positives = 63/85 (74%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+++ AMLTTFNEV+M +M LR +Y + FEK+HG++LGFM F+ KAV ALK P VNA
Sbjct: 215 QSTAAMLTTFNEVDMSAVMALRTKYKDVFEKKHGVKLGFMGFFTKAVTHALKEIPAVNAE 274
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
IDG D++Y N+ V +AV T +GLV
Sbjct: 275 IDGTDIIYKNFAHVGVAVGTEKGLV 299
Score = 68.1 bits (159), Expect = 2e-10
Identities = 29/40 (72%), Positives = 36/40 (90%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
PMMYLALSYDHR++DG+E+V FLV +KE LEDP RL+LD+
Sbjct: 385 PMMYLALSYDHRIVDGKEAVTFLVRVKESLEDPERLVLDL 424
>UniRef50_Q7ULX6 Cluster: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex; n=10;
Bacteria|Rep: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex -
Rhodopirellula baltica
Length = 435
Score = 114 bits (274), Expect = 2e-24
Identities = 48/85 (56%), Positives = 66/85 (77%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+ + A+LTTFNE+NM P+M +R +Y +AF K+HG++LGFMSF+ KA VEAL+RYP VNA
Sbjct: 226 QQTAALLTTFNEINMAPVMAIRSKYKDAFAKKHGVKLGFMSFFAKATVEALRRYPAVNAE 285
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
I GD +VY NY D+ +A+ +GLV
Sbjct: 286 IRGDSMVYRNYQDIGIAIGGGKGLV 310
Score = 101 bits (242), Expect = 2e-20
Identities = 45/83 (54%), Positives = 63/83 (75%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PVLR+V+ + A++E I E A + +L DL GG FTI+NGG++GSL+STPI+NPP
Sbjct: 312 PVLRNVERMSFAEVEGSIAEYARLAGENRLQPSDLMGGTFTISNGGIYGSLLSTPIVNPP 371
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
QS ILG+H+I++RP+A +GQV I
Sbjct: 372 QSGILGLHSIQERPVAEDGQVVI 394
Score = 70.1 bits (164), Expect = 5e-11
Identities = 29/40 (72%), Positives = 36/40 (90%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
PMMY+AL+YDHR++DGRE+VGFLV IKE +EDP RL L+V
Sbjct: 396 PMMYVALTYDHRIVDGREAVGFLVAIKETIEDPARLFLEV 435
>UniRef50_P36957 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial precursor; n=48;
Fungi/Metazoa group|Rep: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial precursor - Homo
sapiens (Human)
Length = 453
Score = 114 bits (274), Expect = 2e-24
Identities = 51/83 (61%), Positives = 64/83 (77%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R+V+ + ADIE+ I EL K +L +ED+ GG FTI+NGGVFGSL TPIINPP
Sbjct: 330 PVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPP 389
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
QSAILGMH I DRP+A+ G+VE+
Sbjct: 390 QSAILGMHGIFDRPVAIGGKVEV 412
Score = 97.1 bits (231), Expect = 4e-19
Identities = 47/87 (54%), Positives = 65/87 (74%), Gaps = 2/87 (2%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+N+ AMLTTFNE++M I ++R ++ EAF K+H ++LGFMS +VKA AL+ P VNA
Sbjct: 242 QNTCAMLTTFNEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAV 301
Query: 181 IDG--DDVVYHNYFDVSMAVSTPRGLV 255
ID +VVY +Y D+S+AV+TPRGLV
Sbjct: 302 IDDTTKEVVYRDYIDISVAVATPRGLV 328
Score = 60.5 bits (140), Expect = 4e-08
Identities = 28/40 (70%), Positives = 33/40 (82%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
PMMY+AL+YDHRLIDGRE+V FL IK +EDP LLLD+
Sbjct: 414 PMMYVALTYDHRLIDGREAVTFLRKIKAAVEDPRVLLLDL 453
>UniRef50_A0LAA3 Cluster: 2-oxoglutarate dehydrogenase, E2 subunit,
dihydrolipoamide succinyltransferase; n=11;
Proteobacteria|Rep: 2-oxoglutarate dehydrogenase, E2
subunit, dihydrolipoamide succinyltransferase -
Magnetococcus sp. (strain MC-1)
Length = 446
Score = 113 bits (271), Expect = 5e-24
Identities = 49/85 (57%), Positives = 67/85 (78%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+N+ AMLTTFNEV+M +M LR QY E FEKR+ RLGFMSF+VKA + AL+ +P VNA
Sbjct: 236 QNTAAMLTTFNEVDMTAVMALRSQYKEVFEKRNHARLGFMSFFVKAAISALQEFPAVNAE 295
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
I G+++V+ NY+D+ +AV +P+GLV
Sbjct: 296 IQGNEIVFKNYYDIGVAVGSPQGLV 320
Score = 97.9 bits (233), Expect = 2e-19
Identities = 44/83 (53%), Positives = 62/83 (74%), Gaps = 1/83 (1%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PVLR D + +A IE I + + DG+L++E+++GG FTITNGG+FGSL+STPI+N P
Sbjct: 322 PVLRGADAMSLAGIESTIAGMGKRARDGQLSMEEMSGGTFTITNGGIFGSLLSTPILNTP 381
Query: 438 QSAILGMHAIKDRPMAV-NGQVE 503
QSAILGMH I+ R M + +G ++
Sbjct: 382 QSAILGMHKIQQRAMVMPDGSIQ 404
Score = 66.1 bits (154), Expect = 8e-10
Identities = 27/39 (69%), Positives = 35/39 (89%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
PMMYLALSYDHR++DG+E+V FLV IK+ +EDP R+LL+
Sbjct: 407 PMMYLALSYDHRIVDGKEAVSFLVRIKDCIEDPARILLN 445
>UniRef50_Q9FLQ4 Cluster: 2-oxoglutarate dehydrogenase E2 subunit;
n=15; Magnoliophyta|Rep: 2-oxoglutarate dehydrogenase E2
subunit - Arabidopsis thaliana (Mouse-ear cress)
Length = 464
Score = 113 bits (271), Expect = 5e-24
Identities = 49/81 (60%), Positives = 64/81 (79%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+RD D + ADIEK I LA K +G ++++++ GG+FT++NGGV+GSL+STPIINPP
Sbjct: 341 PVIRDADKMNFADIEKTINGLAKKATEGTISIDEMAGGSFTVSNGGVYGSLISTPIINPP 400
Query: 438 QSAILGMHAIKDRPMAVNGQV 500
QSAILGMH+I RPM V G V
Sbjct: 401 QSAILGMHSIVQRPMVVGGSV 421
Score = 107 bits (256), Expect = 3e-22
Identities = 47/85 (55%), Positives = 66/85 (77%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+N+ A+LTTFNEV+M +M LR QY +AF ++HG++LG MS ++KA V AL+ P VNA
Sbjct: 255 QNTFALLTTFNEVDMTNLMKLRSQYKDAFLEKHGVKLGLMSGFIKAAVSALQHQPVVNAV 314
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
IDGDD++Y +Y D+S+AV T +GLV
Sbjct: 315 IDGDDIIYRDYVDISIAVGTSKGLV 339
Score = 66.1 bits (154), Expect = 8e-10
Identities = 29/40 (72%), Positives = 36/40 (90%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
PMMY+AL+YDHRLIDGRE+V FL IK+++EDP RLLLD+
Sbjct: 425 PMMYVALTYDHRLIDGREAVYFLRRIKDVVEDPQRLLLDI 464
>UniRef50_A5CEI9 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=1;
Orientia tsutsugamushi Boryong|Rep: 2-oxoglutarate
dehydrogenase, E2 component, dihydrolipoamide
succinyltransferase - Orientia tsutsugamushi (strain
Boryong) (Rickettsia tsutsugamushi)
Length = 425
Score = 112 bits (270), Expect = 7e-24
Identities = 47/83 (56%), Positives = 67/83 (80%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
P++R+ + L A+IE +I +L K +G L++ +L+GG F+ITNGGVFGSL+STPIINPP
Sbjct: 302 PIIRNAEHLSFAEIEMEISQLGKKAREGNLSINELSGGTFSITNGGVFGSLLSTPIINPP 361
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
QSAI+GMH I+DRP+ +NG ++I
Sbjct: 362 QSAIMGMHKIQDRPVVINGTIQI 384
Score = 108 bits (260), Expect = 1e-22
Identities = 48/85 (56%), Positives = 66/85 (77%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+N+ A+L+TFNEV+M + +LRK+Y E FEK+H I+LGFMSF+VKA AL+ P +NA
Sbjct: 216 QNNAAILSTFNEVDMFNVSELRKKYKEEFEKKHEIKLGFMSFFVKAATAALQELPIINAQ 275
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
+DG D++YHNY D+ +AVST GLV
Sbjct: 276 VDGYDILYHNYCDIGVAVSTNSGLV 300
Score = 59.7 bits (138), Expect = 7e-08
Identities = 24/40 (60%), Positives = 32/40 (80%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
PMMY+ LSYDHR+IDG+E+V FL +K +E P RLLL++
Sbjct: 386 PMMYIVLSYDHRIIDGKEAVTFLTKVKSYIESPERLLLNI 425
>UniRef50_Q3SEX1 Cluster: Dihydrolipoamide succinyltransferase; n=1;
Thiobacillus denitrificans ATCC 25259|Rep:
Dihydrolipoamide succinyltransferase - Thiobacillus
denitrificans (strain ATCC 25259)
Length = 379
Score = 111 bits (266), Expect = 2e-23
Identities = 47/85 (55%), Positives = 70/85 (82%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+++ AMLTTFNEVNM+P+ +LR+++ FE RHG++LG+MSF+V+AV AL+ +P VNA
Sbjct: 168 QHTAAMLTTFNEVNMQPVNELRQRFKADFEVRHGVKLGYMSFFVRAVCRALEAFPIVNAR 227
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
IDG+D+V+H D+ +A+S+PRGLV
Sbjct: 228 IDGNDIVWHGDADIGIAISSPRGLV 252
Score = 106 bits (255), Expect = 4e-22
Identities = 49/83 (59%), Positives = 63/83 (75%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
P+LR L +IE+ I + A + D KL +E+L GG F+ITNGGVFGSL+STPI+NPP
Sbjct: 254 PILRRAQQLSSDEIERAIADFARRARDSKLALEELAGGTFSITNGGVFGSLLSTPILNPP 313
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
QSAILGMH I++RP+A +GQV I
Sbjct: 314 QSAILGMHTIQERPVAEHGQVVI 336
Score = 55.2 bits (127), Expect = 1e-06
Identities = 24/33 (72%), Positives = 28/33 (84%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDP 607
PMMYLAL+YDHRLIDGR++V FLV +K LE P
Sbjct: 338 PMMYLALTYDHRLIDGRDAVQFLVAVKAALEAP 370
>UniRef50_Q553V8 Cluster: Dihydrolipoamide S-succinyltransferase;
n=2; Dictyostelium discoideum|Rep: Dihydrolipoamide
S-succinyltransferase - Dictyostelium discoideum AX4
Length = 439
Score = 111 bits (266), Expect = 2e-23
Identities = 52/83 (62%), Positives = 62/83 (74%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R+ + L ADIEK+I L+ + L +ED GG FTI+NGGVFGS+ TPIINPP
Sbjct: 316 PVIRNCENLSFADIEKEIGRLSGLARNDALAIEDSIGGTFTISNGGVFGSMFGTPIINPP 375
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
QSAILGMHAIKDRP VNGQV +
Sbjct: 376 QSAILGMHAIKDRPYVVNGQVVV 398
Score = 108 bits (259), Expect = 1e-22
Identities = 47/85 (55%), Positives = 67/85 (78%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+N+ AMLTTFNE++M +M++RK Y + FEK+HG++ GFMS +VKA ALK P VNAS
Sbjct: 230 QNTAAMLTTFNELDMSALMNMRKTYKDEFEKKHGVKFGFMSAFVKASTIALKEQPIVNAS 289
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
++ +D+VYHN ++++AVS PRGLV
Sbjct: 290 VEENDIVYHNNVNINVAVSAPRGLV 314
Score = 61.7 bits (143), Expect = 2e-08
Identities = 26/40 (65%), Positives = 36/40 (90%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
P+MYLAL+YDHR+IDGRE+V FL IK++LE+P R+LL++
Sbjct: 400 PIMYLALTYDHRIIDGREAVTFLKKIKDVLENPERILLEL 439
>UniRef50_Q49XM4 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=35; Bacillales|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Staphylococcus saprophyticus subsp. saprophyticus
(strain ATCC 15305 /DSM 20229)
Length = 424
Score = 111 bits (266), Expect = 2e-23
Identities = 53/88 (60%), Positives = 67/88 (76%), Gaps = 1/88 (1%)
Frame = +1
Query: 4 NSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRH-GIRLGFMSFYVKAVVEALKRYPEVNAS 180
N+TAMLTTFNE++M +MDLRK+ E F K H G +LGFMSF+ KA V ALK+YPEVNA
Sbjct: 214 NNTAMLTTFNEIDMTNVMDLRKRKKEQFIKDHDGTKLGFMSFFTKAAVAALKKYPEVNAE 273
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLVRRF 264
IDGDD++ Y+D+ +AVST GL+ F
Sbjct: 274 IDGDDMITKQYYDIGVAVSTEDGLLVPF 301
Score = 94.3 bits (224), Expect = 3e-18
Identities = 44/78 (56%), Positives = 58/78 (74%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
P +RD D A+IE +I LA K D KL ++D+ G+FTITNGG+FGS+MSTPIIN
Sbjct: 300 PFVRDCDKKNFAEIEDEIGNLAKKARDKKLGLDDMVNGSFTITNGGIFGSMMSTPIINGS 359
Query: 438 QSAILGMHAIKDRPMAVN 491
Q+AILGMH+I RP+A++
Sbjct: 360 QAAILGMHSIITRPIAID 377
Score = 67.3 bits (157), Expect = 3e-10
Identities = 29/39 (74%), Positives = 36/39 (92%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
PMMY+ALSYDHR+IDG+E+VGFL TIKEL+E+P LLL+
Sbjct: 385 PMMYIALSYDHRIIDGKEAVGFLKTIKELIENPEDLLLE 423
>UniRef50_Q1QQR6 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=2;
Proteobacteria|Rep: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase -
Nitrobacter hamburgensis (strain X14 / DSM 10229)
Length = 413
Score = 110 bits (265), Expect = 3e-23
Identities = 48/85 (56%), Positives = 63/85 (74%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+N+ AMLTTFNEV+M +M LR Y E FEK+HG++LGFM F+ KA V+ALK P NA
Sbjct: 204 QNTAAMLTTFNEVDMTGVMTLRTHYKEVFEKKHGVKLGFMGFFTKACVQALKDIPAANAE 263
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
IDG D++Y NY+ + +AV T +GLV
Sbjct: 264 IDGTDLIYKNYYHIGIAVGTDKGLV 288
Score = 108 bits (260), Expect = 1e-22
Identities = 47/83 (56%), Positives = 65/83 (78%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+RD D +A+IEK I + + DG+L ++++ GG FTITNGG++GSLMSTPI+N P
Sbjct: 290 PVVRDCDRKSIAEIEKSIADYGRRARDGQLKIDEMQGGTFTITNGGIYGSLMSTPILNAP 349
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
Q+ ILGMH I++RPMA+ G+VEI
Sbjct: 350 QAGILGMHKIQERPMAIAGKVEI 372
Score = 67.3 bits (157), Expect = 3e-10
Identities = 29/40 (72%), Positives = 36/40 (90%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
PMMYLALSYDHR+IDG+++V FLV +KE LEDP RL+LD+
Sbjct: 374 PMMYLALSYDHRVIDGKDAVTFLVRVKESLEDPARLVLDL 413
>UniRef50_Q4RLV1 Cluster: Chromosome 10 SCAF15019, whole genome
shotgun sequence; n=5; Bilateria|Rep: Chromosome 10
SCAF15019, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 461
Score = 110 bits (264), Expect = 4e-23
Identities = 51/83 (61%), Positives = 63/83 (75%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R+V+ + ADIEK I L K +L VED+ GG FTI+NGGVFGS+ TPIINPP
Sbjct: 338 PVIRNVEGMNFADIEKAINLLGEKARKNELAVEDMDGGTFTISNGGVFGSMFGTPIINPP 397
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
QSAILGMH I +RP+A+ G+VEI
Sbjct: 398 QSAILGMHGIFERPVAIGGKVEI 420
Score = 96.7 bits (230), Expect = 5e-19
Identities = 47/87 (54%), Positives = 63/87 (72%), Gaps = 2/87 (2%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+N+ AMLTTFNEV+M I ++RK Y +AF K+H I+LGFMS +VKA AL P VN
Sbjct: 250 QNTCAMLTTFNEVDMSNISEMRKTYKDAFLKKHNIKLGFMSAFVKAAAYALADQPAVNGV 309
Query: 181 IDG--DDVVYHNYFDVSMAVSTPRGLV 255
ID ++VY +Y D+S+AV+TP+GLV
Sbjct: 310 IDDTTKEIVYRDYVDISVAVATPKGLV 336
Score = 61.7 bits (143), Expect = 2e-08
Identities = 28/40 (70%), Positives = 34/40 (85%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
PMMY+AL+YDHRLIDGRE+V FL IK ++EDP LLLD+
Sbjct: 422 PMMYVALTYDHRLIDGREAVTFLRKIKSVVEDPRVLLLDM 461
>UniRef50_Q5P9T5 Cluster: Dihydrolipoamide acetyltransferase
component; n=6; Anaplasmataceae|Rep: Dihydrolipoamide
acetyltransferase component - Anaplasma marginale
(strain St. Maries)
Length = 437
Score = 110 bits (264), Expect = 4e-23
Identities = 49/83 (59%), Positives = 65/83 (78%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R +T+ A +E+++ L+ K G LTV D++G FTITNGGV+GSL+STPIINPP
Sbjct: 314 PVIRGAETMSFAALEQELVMLSKKARGGTLTVADMSGATFTITNGGVYGSLLSTPIINPP 373
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
QS ILGMHAI++RP+ VNG +EI
Sbjct: 374 QSGILGMHAIQERPVVVNGNIEI 396
Score = 100 bits (239), Expect = 4e-20
Identities = 42/85 (49%), Positives = 65/85 (76%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+N+ A L+TFNEV+M +M LR +Y E FEK++ ++LGFMSF+++AVV AL+ P +NA
Sbjct: 228 QNTAATLSTFNEVDMSAVMALRGKYKEGFEKKYEVKLGFMSFFIRAVVLALREIPVINAE 287
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
I GD+++Y +Y ++ +AV T +GLV
Sbjct: 288 ISGDEIIYRDYCNIGVAVGTDKGLV 312
Score = 60.9 bits (141), Expect = 3e-08
Identities = 24/40 (60%), Positives = 34/40 (85%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
PMMYLALSYDHR++DG+ +V FLV +K+ +EDP R+ L++
Sbjct: 398 PMMYLALSYDHRIVDGQGAVTFLVRVKQYIEDPNRMSLEI 437
>UniRef50_UPI00015B5B2E Cluster: PREDICTED: similar to
ENSANGP00000010144; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000010144 - Nasonia
vitripennis
Length = 483
Score = 109 bits (262), Expect = 6e-23
Identities = 52/83 (62%), Positives = 62/83 (74%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PVLR V+ A+IE + + K GK++VED+ GG FTI+NGGVFGSLM TPIINPP
Sbjct: 360 PVLRSVENKNFAEIEIAMAAVGDKARKGKISVEDMDGGTFTISNGGVFGSLMGTPIINPP 419
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
QSAILGMH + DRP+AV GQV I
Sbjct: 420 QSAILGMHGVFDRPIAVKGQVVI 442
Score = 104 bits (250), Expect = 2e-21
Identities = 46/85 (54%), Positives = 66/85 (77%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+N+ AMLTTFNE++M ++D RK E+F+K++G++LGFMS ++ A ALK P VNA
Sbjct: 274 QNTNAMLTTFNEIDMSALIDFRKSNQESFQKKYGLKLGFMSPFIAASAYALKDQPVVNAV 333
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
IDG D+VY +Y D+S+AV+TP+GLV
Sbjct: 334 IDGTDIVYRDYVDISVAVATPKGLV 358
Score = 56.0 bits (129), Expect = 8e-07
Identities = 25/37 (67%), Positives = 31/37 (83%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLL 619
PMMY+AL+YDHRLIDGRE+V FL IK+ +EDP +L
Sbjct: 444 PMMYVALTYDHRLIDGREAVMFLRKIKDAVEDPRIIL 480
>UniRef50_O84058 Cluster: Dihydrolipoamide Succinyltransferase; n=7;
Chlamydiaceae|Rep: Dihydrolipoamide Succinyltransferase
- Chlamydia trachomatis
Length = 365
Score = 108 bits (259), Expect = 1e-22
Identities = 45/84 (53%), Positives = 70/84 (83%)
Frame = +1
Query: 4 NSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASI 183
+ +AMLTTFNE++M P++ LRK+ E F ++G++LGFMSF+V+AVV++LK+YP VNA I
Sbjct: 158 HDSAMLTTFNEIHMGPLIALRKERQEDFVAKYGVKLGFMSFFVRAVVDSLKKYPRVNAYI 217
Query: 184 DGDDVVYHNYFDVSMAVSTPRGLV 255
+ +++VY +Y+D+S+A+ T RGLV
Sbjct: 218 EDNEIVYRHYYDISIAIGTDRGLV 241
Score = 97.5 bits (232), Expect = 3e-19
Identities = 43/75 (57%), Positives = 57/75 (76%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R+ D L +IE ++ +LA + +GKL + +L GG FTITNGGV+GSL+STPIINPP
Sbjct: 243 PVIRNCDQLSSGEIELQLADLASRAREGKLAIHELEGGGFTITNGGVYGSLLSTPIINPP 302
Query: 438 QSAILGMHAIKDRPM 482
Q ILGMH I+ RP+
Sbjct: 303 QVGILGMHKIEKRPV 317
Score = 58.8 bits (136), Expect = 1e-07
Identities = 25/36 (69%), Positives = 31/36 (86%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLL 619
MMY+A+SYDHR+IDG+E+VGFLV +KE LE P LL
Sbjct: 328 MMYVAMSYDHRIIDGKEAVGFLVNVKEQLEQPELLL 363
>UniRef50_Q234F3 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
2-oxoglutarate dehydrogenase, E2 component,
dihydrolipoamide succinyltransferase family protein -
Tetrahymena thermophila SB210
Length = 564
Score = 108 bits (259), Expect = 1e-22
Identities = 46/85 (54%), Positives = 67/85 (78%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+N+ A+L TFNEV+M +M++R +Y E F+K+H ++LGFMSF+VKA AL++ P VNA
Sbjct: 355 QNTYALLPTFNEVDMSNVMEIRNKYQEQFQKKHNVKLGFMSFFVKAATAALQQQPIVNAV 414
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
IDG ++VY NY D+S+AV+TP GL+
Sbjct: 415 IDGKEIVYRNYVDISVAVATPTGLM 439
Score = 104 bits (249), Expect = 2e-21
Identities = 44/81 (54%), Positives = 61/81 (75%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PVLR+ + + AD+E++I L KG +G +TVED+ GG FTI+NGG +GSL PI+NPP
Sbjct: 441 PVLRNTENMSFADVEREIIRLGNKGKEGSITVEDMVGGTFTISNGGTYGSLFGMPILNPP 500
Query: 438 QSAILGMHAIKDRPMAVNGQV 500
QSAILGMHA+++RP+ Q+
Sbjct: 501 QSAILGMHAVQNRPVVRGDQI 521
Score = 66.9 bits (156), Expect = 4e-10
Identities = 28/40 (70%), Positives = 37/40 (92%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
PMMYLAL+YDHRLIDGRE+V FL TIKE++E+P++LL ++
Sbjct: 525 PMMYLALTYDHRLIDGREAVTFLKTIKEIVEEPSKLLFEI 564
>UniRef50_Q2UQN3 Cluster: Dihydrolipoamide succinyltransferase; n=3;
Trichocomaceae|Rep: Dihydrolipoamide succinyltransferase
- Aspergillus oryzae
Length = 448
Score = 108 bits (259), Expect = 1e-22
Identities = 48/84 (57%), Positives = 68/84 (80%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TPVLR+++ G+ +IE+ I EL K DGKLT++DL GG+FTI+N G++GSL TPIIN
Sbjct: 325 TPVLRNMERQGIVEIEQGIAELGKKARDGKLTMDDLVGGSFTISNSGIWGSLFGTPIINI 384
Query: 435 PQSAILGMHAIKDRPMAVNGQVEI 506
PQ+A+LG++ I+ RP+A++GQVEI
Sbjct: 385 PQTAVLGIYGIQQRPVAIDGQVEI 408
Score = 90.2 bits (214), Expect = 4e-17
Identities = 42/86 (48%), Positives = 61/86 (70%), Gaps = 1/86 (1%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+N+ A LTTFNE +M IM LR Q + ++HG++LGFM +A AL+ P +NAS
Sbjct: 239 QNTAAFLTTFNEADMSKIMALRSQNKDDVLQKHGVKLGFMGPVARASALALREIPAINAS 298
Query: 181 IDGDD-VVYHNYFDVSMAVSTPRGLV 255
I+ DD +V+H+Y D+S+AV+TP+GLV
Sbjct: 299 IENDDTIVFHDYIDLSVAVATPKGLV 324
Score = 58.8 bits (136), Expect = 1e-07
Identities = 24/38 (63%), Positives = 31/38 (81%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
PMMY AL+YDHRL+DGRE+V FL +K+ LEDP +L+
Sbjct: 410 PMMYTALTYDHRLVDGREAVTFLTLVKKYLEDPASMLI 447
>UniRef50_A0LP66 Cluster: 2-oxoglutarate dehydrogenase, E2 subunit,
dihydrolipoamide succinyltransferase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: 2-oxoglutarate
dehydrogenase, E2 subunit, dihydrolipoamide
succinyltransferase - Syntrophobacter fumaroxidans
(strain DSM 10017 / MPOB)
Length = 444
Score = 106 bits (255), Expect = 4e-22
Identities = 48/83 (57%), Positives = 64/83 (77%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+RDVD LG AD+EK I + K + +L + DL GG FTI+NGGV+GSLMSTPI+N P
Sbjct: 321 PVIRDVDKLGFADLEKAILDHVRKIRENRLEMSDLEGGTFTISNGGVYGSLMSTPILNSP 380
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
QS ILG+H I+DRP+ V+G++ +
Sbjct: 381 QSGILGLHKIEDRPVVVDGRIVV 403
Score = 103 bits (247), Expect = 4e-21
Identities = 43/83 (51%), Positives = 62/83 (74%)
Frame = +1
Query: 7 STAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID 186
+TAMLTTFNE++M + ++RKQ+ + F+K+H + LG MSF++KA ALK PE+NA I+
Sbjct: 237 NTAMLTTFNEIDMSRLQEIRKQFRDLFQKKHSVSLGIMSFFLKAAAVALKELPELNAFIE 296
Query: 187 GDDVVYHNYFDVSMAVSTPRGLV 255
G ++VYHNY + +AV RGLV
Sbjct: 297 GHEIVYHNYIHIGVAVGAERGLV 319
Score = 61.3 bits (142), Expect = 2e-08
Identities = 24/40 (60%), Positives = 35/40 (87%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
PMMY+ALSYDHR++DGRE+V FL IKE +E+P R+++++
Sbjct: 405 PMMYVALSYDHRIVDGREAVTFLKRIKECIENPERIMVEI 444
>UniRef50_A0H458 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=2;
Chloroflexus|Rep: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase -
Chloroflexus aggregans DSM 9485
Length = 469
Score = 106 bits (255), Expect = 4e-22
Identities = 49/83 (59%), Positives = 63/83 (75%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+RD D A IE++I +LA K +G L++ +L GG FTITNGGV+GSLMSTPI+N P
Sbjct: 346 PVVRDADRKTFAQIEREIAQLAKKAREGTLSLAELQGGTFTITNGGVYGSLMSTPILNAP 405
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
Q ILGMH I++RP+ VNGQ+ I
Sbjct: 406 QVGILGMHKIEERPVVVNGQIVI 428
Score = 99 bits (238), Expect = 5e-20
Identities = 44/85 (51%), Positives = 64/85 (75%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+++ AMLTTFNEV+M +M LR ++ ++F++RHG+ LG+MSF+ KAVV ALK +P VNA
Sbjct: 260 QHTAAMLTTFNEVDMSAVMALRARHKDSFKERHGVSLGYMSFFTKAVVGALKAFPMVNAE 319
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
I G++VV Y+D+ +AV GLV
Sbjct: 320 IQGEEVVIKYYYDIGIAVGVDEGLV 344
Score = 62.9 bits (146), Expect = 7e-09
Identities = 28/39 (71%), Positives = 33/39 (84%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
PMMY+ALSYDHRLIDG +V FLV +KEL+EDP LLL+
Sbjct: 430 PMMYVALSYDHRLIDGSTAVRFLVKVKELIEDPEALLLE 468
>UniRef50_O94681 Cluster: Probable dihydrolipoyllysine-residue
succinyltransferase component of 2-oxoglutarate
dehydrogenase complex, mitochondrial precursor; n=1;
Schizosaccharomyces pombe|Rep: Probable
dihydrolipoyllysine-residue succinyltransferase
component of 2-oxoglutarate dehydrogenase complex,
mitochondrial precursor - Schizosaccharomyces pombe
(Fission yeast)
Length = 452
Score = 105 bits (252), Expect = 1e-21
Identities = 45/82 (54%), Positives = 62/82 (75%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TPV+R+ +++ + +IE I L K GKL +ED+ G FTI+NGG+FGSL TPIIN
Sbjct: 329 TPVIRNAESMSLLEIESAIATLGSKARAGKLAIEDMASGTFTISNGGIFGSLYGTPIINL 388
Query: 435 PQSAILGMHAIKDRPMAVNGQV 500
PQ+A+LG+HAIK+RP+ +NGQV
Sbjct: 389 PQTAVLGLHAIKERPVVINGQV 410
Score = 89.0 bits (211), Expect = 1e-16
Identities = 41/89 (46%), Positives = 63/89 (70%), Gaps = 4/89 (4%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+N A LTTFNE +M ++ LRK+Y + K G+++GFMSF+ KA +A+K+ P +N S
Sbjct: 240 QNRAASLTTFNECDMSAVVALRKKYKDEILKETGVKIGFMSFFSKACTQAMKQIPAINGS 299
Query: 181 ID----GDDVVYHNYFDVSMAVSTPRGLV 255
I+ GD +VY ++ D+S+AV+TP+GLV
Sbjct: 300 IEGEGKGDTLVYRDFCDLSIAVATPKGLV 328
Score = 61.7 bits (143), Expect = 2e-08
Identities = 25/38 (65%), Positives = 33/38 (86%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
PMMYLAL+YDHR++DGRE+V FL +KE +EDP ++LL
Sbjct: 414 PMMYLALTYDHRMVDGREAVTFLRLVKEYIEDPAKMLL 451
>UniRef50_Q5FS04 Cluster: Dihydrolipoamide succinyl transferase (E2)
of 2-oxoglutarate dehydrogenase; n=6; cellular
organisms|Rep: Dihydrolipoamide succinyl transferase
(E2) of 2-oxoglutarate dehydrogenase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 369
Score = 104 bits (249), Expect = 2e-21
Identities = 48/86 (55%), Positives = 65/86 (75%), Gaps = 1/86 (1%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRH-GIRLGFMSFYVKAVVEALKRYPEVNA 177
+N+ A+LTTFNE++M LR QY E FEK+H G RLGFMSF+ +AVV ALK YP +NA
Sbjct: 159 QNTAAILTTFNEIDMSAAKALRAQYKEEFEKKHDGARLGFMSFFARAVVGALKDYPAINA 218
Query: 178 SIDGDDVVYHNYFDVSMAVSTPRGLV 255
I+GD++VY ++ ++ +AV T RGLV
Sbjct: 219 QIEGDEIVYRDFVNLGIAVGTERGLV 244
Score = 100 bits (240), Expect = 3e-20
Identities = 44/83 (53%), Positives = 62/83 (74%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PVL D D + A++E++I + + G L +E+L+ G F+ITNGG+FGSL+STPI+N P
Sbjct: 246 PVLHDADQMSFAELERRIADYGKRARTGGLKLEELSHGTFSITNGGIFGSLLSTPILNTP 305
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
QS ILGMHAI+DRP+ +GQ+ I
Sbjct: 306 QSGILGMHAIQDRPVVRDGQIVI 328
Score = 70.5 bits (165), Expect = 4e-11
Identities = 30/40 (75%), Positives = 37/40 (92%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
PMMY+ALSYDHR++DGRE+V FLV IK+L+EDP RLLLD+
Sbjct: 330 PMMYVALSYDHRIVDGREAVSFLVRIKQLVEDPRRLLLDL 369
>UniRef50_Q4Q822 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase,
putative; n=5; Trypanosomatidae|Rep: 2-oxoglutarate
dehydrogenase, E2 component, dihydrolipoamide
succinyltransferase, putative - Leishmania major
Length = 389
Score = 104 bits (249), Expect = 2e-21
Identities = 47/83 (56%), Positives = 61/83 (73%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+RDV + +A+IE I + A + KLT+ ++TGG FTI+NGGVFGS M TPIINPP
Sbjct: 265 PVIRDVQNMNLANIETAIADYAARARINKLTMAEMTGGTFTISNGGVFGSWMGTPIINPP 324
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
SAILGMHAIK +P V +++I
Sbjct: 325 HSAILGMHAIKKKPWVVGNEIKI 347
Score = 98.7 bits (235), Expect = 1e-19
Identities = 45/85 (52%), Positives = 61/85 (71%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+N+ AMLTTFNE++M P+ LR +Y + F KRH ++LG MS +VKA ALK P VNAS
Sbjct: 179 QNTCAMLTTFNEIDMTPLFQLRDKYKDEFHKRHDVKLGLMSPFVKASAIALKDVPIVNAS 238
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
D + YH + D+++AV+TPRGLV
Sbjct: 239 FGKDTIDYHEFVDIAIAVATPRGLV 263
Score = 55.6 bits (128), Expect = 1e-06
Identities = 23/39 (58%), Positives = 33/39 (84%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
+M +AL+YDHRLIDG ++V FLV +K L+EDP R++LD+
Sbjct: 350 IMAVALTYDHRLIDGSDAVTFLVKVKNLIEDPARMVLDL 388
>UniRef50_Q7RIU5 Cluster: 2-oxoglutarate dehydrogenase, E2 component,
dihydrolipoamide succinyltransferase, putative; n=12;
cellular organisms|Rep: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase, putative
- Plasmodium yoelii yoelii
Length = 1632
Score = 103 bits (248), Expect = 3e-21
Identities = 45/83 (54%), Positives = 62/83 (74%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+RD + +E + ++A K + KL+++D TGG FTI+NGGVFGS++STPIIN P
Sbjct: 1509 PVIRDCQNKNLPQLELALSDIAAKAKNNKLSLDDFTGGTFTISNGGVFGSMLSTPIINMP 1568
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
QSAILGMH IK+RP+ VN ++ I
Sbjct: 1569 QSAILGMHTIKNRPVVVNNEIVI 1591
Score = 93.9 bits (223), Expect = 3e-18
Identities = 41/84 (48%), Positives = 62/84 (73%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+N+ A+LTTFNE +M + LR + + F+K++G +LGF+S ++ A ALK+ P+VNA
Sbjct: 1423 QNTCALLTTFNECDMSKAIVLRTELKDIFQKKYGCKLGFVSLFLYASTLALKKMPQVNAY 1482
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGL 252
ID D++VY NY D+S+AV+TP GL
Sbjct: 1483 IDNDEIVYKNYIDISVAVATPNGL 1506
Score = 58.8 bits (136), Expect = 1e-07
Identities = 24/39 (61%), Positives = 33/39 (84%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
P+MYLAL+YDHRL+DGRE+V FL IK+ +E+P +L+D
Sbjct: 1593 PVMYLALTYDHRLLDGREAVQFLCAIKDYIENPNLMLID 1631
>UniRef50_Q3A0D1 Cluster: 2-oxoglutarate dehydrogenase, E2
component/dihydrolipoamide succinyltransferase; n=2;
Desulfuromonadales|Rep: 2-oxoglutarate dehydrogenase, E2
component/dihydrolipoamide succinyltransferase -
Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1)
Length = 396
Score = 102 bits (245), Expect = 7e-21
Identities = 47/81 (58%), Positives = 62/81 (76%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PVL + D L ADIEK+I ELA K +L + DL GG F+I+NGGV+GSL+STP++NPP
Sbjct: 274 PVLLNADRLNFADIEKQIAELAEKARKHRLALADLQGGTFSISNGGVYGSLLSTPLLNPP 333
Query: 438 QSAILGMHAIKDRPMAVNGQV 500
QSAILGMH+I+ RP+ + Q+
Sbjct: 334 QSAILGMHSIQQRPVVRDDQI 354
Score = 101 bits (242), Expect = 2e-20
Identities = 43/85 (50%), Positives = 65/85 (76%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+ TAM TT NE ++ IM+LR QYGE F +R+GI+LG MSF+VKA VEAL+ +P +NA
Sbjct: 188 RQQTAMATTINEADLSRIMELRSQYGERFMERNGIKLGLMSFFVKACVEALREFPVINAR 247
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
++ + +VY +++D+ +AV+T +GLV
Sbjct: 248 LEEEAIVYQHFYDIGIAVATDQGLV 272
Score = 56.8 bits (131), Expect = 5e-07
Identities = 25/39 (64%), Positives = 31/39 (79%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
PMMYLALSYDHRLIDGR++V FL + E +E+P LL+
Sbjct: 358 PMMYLALSYDHRLIDGRDAVNFLKRVVERVEEPEESLLE 396
>UniRef50_P16263 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=95; Bacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Bacillus subtilis
Length = 417
Score = 102 bits (245), Expect = 7e-21
Identities = 49/78 (62%), Positives = 60/78 (76%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+RD D L A IEK+I ELA K + KLT+ +L GG+FTITNGG FGSLMSTPI+N P
Sbjct: 293 PVVRDADRLTFAGIEKEIGELAKKARNNKLTLSELEGGSFTITNGGTFGSLMSTPILNSP 352
Query: 438 QSAILGMHAIKDRPMAVN 491
Q ILGMH I+ RP+A++
Sbjct: 353 QVGILGMHKIQLRPVAID 370
Score = 94.7 bits (225), Expect = 2e-18
Identities = 41/85 (48%), Positives = 65/85 (76%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+ ++AMLTTFNEV+M +M+LRK+ + F +++ ++LGFMSF+ KAVV ALK+YP +NA
Sbjct: 207 QQTSAMLTTFNEVDMTAVMNLRKRRKDQFFEQNEVKLGFMSFFTKAVVAALKKYPLLNAE 266
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
I GD+++ ++D+ +AV+ GLV
Sbjct: 267 IQGDELIVKKFYDIGIAVAAVEGLV 291
Score = 71.3 bits (167), Expect = 2e-11
Identities = 30/39 (76%), Positives = 37/39 (94%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
PMMY+ALSYDHR++DG+E+VGFLVTIK LLEDP +LLL+
Sbjct: 378 PMMYIALSYDHRIVDGKEAVGFLVTIKNLLEDPEQLLLE 416
>UniRef50_Q6MC86 Cluster: Probable dihydrolipoamide
S-succinyltransferase, (2-oxogluturate dehydrogenase
complex E2 component), sucB; n=1; Candidatus
Protochlamydia amoebophila UWE25|Rep: Probable
dihydrolipoamide S-succinyltransferase, (2-oxogluturate
dehydrogenase complex E2 component), sucB -
Protochlamydia amoebophila (strain UWE25)
Length = 404
Score = 100 bits (240), Expect = 3e-20
Identities = 47/83 (56%), Positives = 58/83 (69%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R D A IE I A K DGK+ ++DL GG FTITNGGV+GSL+STPI+NPP
Sbjct: 281 PVVRQCDQQSFAQIELAIDLFAKKARDGKIAMDDLQGGGFTITNGGVYGSLLSTPILNPP 340
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
Q AILGMH I+ RP+ + Q+ I
Sbjct: 341 QCAILGMHKIEKRPVVMEDQIVI 363
Score = 99.5 bits (237), Expect = 7e-20
Identities = 44/83 (53%), Positives = 64/83 (77%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+ + AMLTTFNEV++ I+ LR+++ E F K++GI+LGFMSF+VKAVV ALK +P VN+
Sbjct: 195 QQTMAMLTTFNEVDLSEIISLREKHQEIFIKKYGIKLGFMSFFVKAVVSALKAFPTVNSY 254
Query: 181 IDGDDVVYHNYFDVSMAVSTPRG 249
+D D+V +Y+D+ +AV T RG
Sbjct: 255 LDQQDIVERHYYDIGIAVGTERG 277
Score = 69.7 bits (163), Expect = 6e-11
Identities = 32/40 (80%), Positives = 36/40 (90%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
PMMYLALSYDHRLIDG+ESV FLV IK LEDP+RLLL++
Sbjct: 365 PMMYLALSYDHRLIDGKESVAFLVHIKNALEDPSRLLLNL 404
>UniRef50_Q0E0X4 Cluster: Os02g0514700 protein; n=2; Oryza
sativa|Rep: Os02g0514700 protein - Oryza sativa subsp.
japonica (Rice)
Length = 497
Score = 99 bits (238), Expect = 5e-20
Identities = 45/85 (52%), Positives = 61/85 (71%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+N+ AML TFNEV+M +M L Y + F ++HG++LG MS +VKA V AL+ P VNA
Sbjct: 288 QNTFAMLITFNEVDMTNLMKLLSDYKDQFVEKHGVKLGLMSCFVKAAVSALQNQPIVNAV 347
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
IDGDD++Y Y D+S+AV T +GLV
Sbjct: 348 IDGDDIIYREYIDISVAVGTSKGLV 372
Score = 99 bits (238), Expect = 5e-20
Identities = 45/80 (56%), Positives = 59/80 (73%)
Frame = +3
Query: 261 VLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPPQ 440
V+ D+D + ADIEK I LA K +G ++ ++ GG FTI+NGGV+GSL+STPIIN PQ
Sbjct: 375 VIHDIDAMNFADIEKGINNLAKKATEGAQSINNMAGGTFTISNGGVYGSLISTPIINSPQ 434
Query: 441 SAILGMHAIKDRPMAVNGQV 500
S+ILGMH+I R + VNG V
Sbjct: 435 SSILGMHSIVQRLVVVNGSV 454
Score = 66.1 bits (154), Expect = 8e-10
Identities = 30/40 (75%), Positives = 35/40 (87%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
PMMYLAL YDHRLIDGRE+V FL IK+++EDP RLLLD+
Sbjct: 458 PMMYLALMYDHRLIDGREAVLFLRRIKDVVEDPRRLLLDI 497
>UniRef50_Q4UGK1 Cluster: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex,
mitochondrial, putative; n=2; Theileria|Rep:
Dihydrolipoamide succinyltransferase component of
2-oxoglutarate dehydrogenase complex, mitochondrial,
putative - Theileria annulata
Length = 457
Score = 98.7 bits (235), Expect = 1e-19
Identities = 44/83 (53%), Positives = 61/83 (73%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R+ + ++E + E+A K DG +T+ED+TGG FTI+NGGV+GSL+STPIINPP
Sbjct: 335 PVIRNCEFKNWEELELSLLEMAKKARDGSITIEDMTGGTFTISNGGVYGSLLSTPIINPP 394
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
QS+ILGMHAI R + + + I
Sbjct: 395 QSSILGMHAITKRAVVRDDNIVI 417
Score = 69.3 bits (162), Expect = 8e-11
Identities = 35/85 (41%), Positives = 54/85 (63%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+ MLTTFNE +M + +RK E+ E +LGF+S +++A AL + P +N+
Sbjct: 251 QTENVMLTTFNECDMSELTKVRKMLNESGEV--SCKLGFVSAFMRASTLALLKMPIMNSY 308
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
IDG ++V NY D+S+AV+TP GL+
Sbjct: 309 IDGKEMVTKNYVDISVAVATPTGLL 333
Score = 54.4 bits (125), Expect = 3e-06
Identities = 24/38 (63%), Positives = 33/38 (86%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
P+M +AL+YDHRLIDGR++V FL TIK+ +E+P+ LLL
Sbjct: 419 PVMNVALTYDHRLIDGRDAVTFLNTIKKFIENPSLLLL 456
>UniRef50_A7AQM6 Cluster: Dihydrolipoamide succinyltransferase,
putative; n=1; Babesia bovis|Rep: Dihydrolipoamide
succinyltransferase, putative - Babesia bovis
Length = 402
Score = 96.3 bits (229), Expect = 6e-19
Identities = 43/83 (51%), Positives = 64/83 (77%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R+ + ++E+++ + A KG +G+LTV D+TGG FTI+NGGV+GS++STPIINPP
Sbjct: 280 PVIRNCEGKSWIELEQQLVDAAAKGREGRLTVADMTGGTFTISNGGVYGSVLSTPIINPP 339
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
QS+ILGMH+I R + + Q+ I
Sbjct: 340 QSSILGMHSIIKRCVVRDDQMVI 362
Score = 79.4 bits (187), Expect = 8e-14
Identities = 38/85 (44%), Positives = 61/85 (71%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+ +T ML+TFNE +M IM LRK+ E+ ++ ++LG++S Y+KA AL + P +N+
Sbjct: 196 QQTTVMLSTFNECDMDAIMALRKELNES--GKYPVKLGYVSAYMKASTMALLKMPIMNSY 253
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
I+GDD+V ++ D+S+AV+TP GLV
Sbjct: 254 IEGDDIVTKHFVDISVAVATPTGLV 278
Score = 56.8 bits (131), Expect = 5e-07
Identities = 26/37 (70%), Positives = 31/37 (83%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLL 619
P+M LALSYDHRLIDGRE+V FL+ IKE +E+P LL
Sbjct: 364 PIMNLALSYDHRLIDGREAVQFLIAIKEAIENPKVLL 400
>UniRef50_UPI000023F136 Cluster: hypothetical protein FG10947.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG10947.1 - Gibberella zeae PH-1
Length = 442
Score = 92.3 bits (219), Expect = 1e-17
Identities = 38/84 (45%), Positives = 61/84 (72%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TPVLR+ ++L + ++E+ + A K DGKLT+ED+ GG+F+I+N G+FGS+ TP+IN
Sbjct: 319 TPVLRNTESLSIVELERAVAAAAKKARDGKLTMEDMEGGSFSISNPGIFGSMFGTPVINY 378
Query: 435 PQSAILGMHAIKDRPMAVNGQVEI 506
PQ+A+ M+ I+ +A+NG+ I
Sbjct: 379 PQAAVFNMNGIRQEVVAINGEAVI 402
Score = 82.2 bits (194), Expect = 1e-14
Identities = 38/87 (43%), Positives = 57/87 (65%), Gaps = 2/87 (2%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+N+ A LTT EV+M ++ R +Y E + HG+RLG+M + KA A ++ P++NA
Sbjct: 232 QNTCASLTTIQEVDMSNLIAWRAKYKEEVAEEHGVRLGYMGAFTKATTIAAQKVPQINAQ 291
Query: 181 IDGDD--VVYHNYFDVSMAVSTPRGLV 255
ID + + YH+Y DVS+AVS P+GLV
Sbjct: 292 IDTEKEIITYHDYVDVSIAVSAPKGLV 318
Score = 60.5 bits (140), Expect = 4e-08
Identities = 25/38 (65%), Positives = 34/38 (89%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
PMMY++L+YDHRLIDGRE+ FL T+K+ +EDP+R+LL
Sbjct: 404 PMMYISLTYDHRLIDGREASMFLNTVKKYIEDPSRMLL 441
>UniRef50_A6WD54 Cluster: 2-oxoglutarate dehydrogenase E2 component;
n=5; Actinomycetales|Rep: 2-oxoglutarate dehydrogenase
E2 component - Kineococcus radiotolerans SRS30216
Length = 618
Score = 86.2 bits (204), Expect = 7e-16
Identities = 41/83 (49%), Positives = 59/83 (71%)
Frame = +1
Query: 7 STAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID 186
++A LTT EV++ I LR + + F G +L F+ F+VKA VEALK++P +NASID
Sbjct: 406 NSAQLTTVIEVDVTKIARLRARAKDGFLATEGAKLTFLPFFVKAAVEALKQHPSLNASID 465
Query: 187 GDDVVYHNYFDVSMAVSTPRGLV 255
G+++VYH +VSMAV TP+GL+
Sbjct: 466 GENIVYHGSENVSMAVDTPKGLI 488
Score = 80.2 bits (189), Expect = 4e-14
Identities = 41/86 (47%), Positives = 55/86 (63%), Gaps = 2/86 (2%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TPV++D L + + +KI +LA + K+T +DL+GG FTITN G G+L TPI+N
Sbjct: 489 TPVIKDAGDLNLGGLARKIADLAARTRASKITPDDLSGGTFTITNTGSIGALFDTPILNA 548
Query: 435 PQSAILGMHAIKDRP--MAVNGQVEI 506
PQ AILG AI RP + V+GQ I
Sbjct: 549 PQVAILGTGAIVKRPVVLEVDGQETI 574
Score = 44.0 bits (99), Expect = 0.004
Identities = 17/30 (56%), Positives = 25/30 (83%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLE 601
MMYLALSYDH+++DG ++ FL T+K+ +E
Sbjct: 579 MMYLALSYDHQIVDGADAARFLQTVKKRIE 608
>UniRef50_A0LSF1 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Acidothermus
cellulolyticus 11B|Rep: Catalytic domain of components
of various dehydrogenase complexes - Acidothermus
cellulolyticus (strain ATCC 43068 / 11B)
Length = 449
Score = 81.4 bits (192), Expect = 2e-14
Identities = 35/83 (42%), Positives = 58/83 (69%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+RD DTLG+ +I ++ ++LA + GKL +D+ G FTI+N G+FG T +INPP
Sbjct: 328 PVIRDADTLGIREISQRTRDLATRARQGKLKPDDIGGSTFTISNLGMFGVDQFTAVINPP 387
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
++AIL + A+++ P+ +GQ+ +
Sbjct: 388 EAAILAVGAVREVPVVRDGQLAV 410
Score = 46.8 bits (106), Expect = 5e-04
Identities = 21/75 (28%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Frame = +1
Query: 37 VNMKPIMDLRKQYGEAFEKRHG--IRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHN 210
+N +P++D+R + A ++ VK AL+++PEVN S G+ ++ H
Sbjct: 252 LNAEPLIDVRARLNAALSSADPDTAKISLNDLIVKVAAAALRKHPEVNVSYAGEKLLQHK 311
Query: 211 YFDVSMAVSTPRGLV 255
+ + +AV+ P GL+
Sbjct: 312 HIHIGVAVAIPDGLI 326
Score = 36.3 bits (80), Expect = 0.71
Identities = 16/36 (44%), Positives = 22/36 (61%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLL 619
+M + LS DHR +DG + GFL + LLE+P L
Sbjct: 413 VMTITLSIDHRALDGATAAGFLADLVTLLENPLAAL 448
>UniRef50_Q0RVL0 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=1; Rhodococcus sp. RHA1|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Rhodococcus sp. (strain RHA1)
Length = 422
Score = 79.8 bits (188), Expect = 6e-14
Identities = 38/81 (46%), Positives = 53/81 (65%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+RD D L + I ++ +E A+ + K+T DLTGG FT+TN G +GS TP++N P
Sbjct: 300 PVVRDADQLSLRAIHQRSEEAALAARERKVTAADLTGGTFTVTNIGSYGSHFGTPVLNLP 359
Query: 438 QSAILGMHAIKDRPMAVNGQV 500
Q AIL AI DRP+ +G+V
Sbjct: 360 QVAILATGAILDRPVVRDGEV 380
Score = 62.5 bits (145), Expect = 9e-09
Identities = 36/117 (30%), Positives = 63/117 (53%), Gaps = 4/117 (3%)
Frame = +1
Query: 7 STAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID 186
+TA LT EV + +++LR + E R G ++ F ++KA AL+ PE+N ++
Sbjct: 217 TTAQLTDVREVEVSALVELRNRLAAKAE-RIGFKVSFTDLFLKATALALREVPELNVTVQ 275
Query: 187 GDDVVYHNYFDVSMAVSTPRGL----VRRFCVMSIPSAWQTSRRKSKSWQSKDVTAS 345
D ++ H++ + MAVS P GL VR +S+ + Q S + + + + VTA+
Sbjct: 276 ADRIIEHDHVHLGMAVSVPDGLIVPVVRDADQLSLRAIHQRSEEAALAARERKVTAA 332
Score = 34.7 bits (76), Expect = 2.2
Identities = 16/37 (43%), Positives = 26/37 (70%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
+++L+L+ DHR+IDG + F T+ LL +P RLL+
Sbjct: 385 VVHLSLTVDHRIIDGELAGRFHNTMAALLAEPDRLLV 421
>UniRef50_Q8RD59 Cluster: Dihydrolipoamide acyltransferases; n=1;
Thermoanaerobacter tengcongensis|Rep: Dihydrolipoamide
acyltransferases - Thermoanaerobacter tengcongensis
Length = 414
Score = 78.2 bits (184), Expect = 2e-13
Identities = 37/83 (44%), Positives = 56/83 (67%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R+VD G+ +I ++ K L K +GKLT ++ TGG+FTI+N G+F + IINPP
Sbjct: 293 PVIREVDKKGLKEIAREEKALIQKAREGKLTPDEYTGGSFTISNLGMFDVVRFAAIINPP 352
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
+ AIL + I++ P+ GQ+EI
Sbjct: 353 EVAILAVGKIREIPVVEEGQIEI 375
Score = 44.4 bits (100), Expect = 0.003
Identities = 20/38 (52%), Positives = 27/38 (71%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
P+M + LS DHR+IDG + FL IKE+LEDP + +L
Sbjct: 377 PIMEMTLSSDHRVIDGALAAKFLRRIKEILEDPLQFML 414
Score = 37.9 bits (84), Expect = 0.23
Identities = 19/74 (25%), Positives = 37/74 (50%)
Frame = +1
Query: 34 EVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNY 213
EV M+ I+ LR+ K ++ + +KA A+K YP N+ ++ ++ N
Sbjct: 219 EVKMREILKLRETLNSKL-KEDEAKISLNTLLMKAAGIAIKDYPIFNSYVEEGQIILRNE 277
Query: 214 FDVSMAVSTPRGLV 255
++ +AV+ GL+
Sbjct: 278 INIGLAVALDEGLI 291
>UniRef50_Q8R9E5 Cluster: Dihydrolipoamide acyltransferases; n=3;
Bacteria|Rep: Dihydrolipoamide acyltransferases -
Thermoanaerobacter tengcongensis
Length = 219
Score = 78.2 bits (184), Expect = 2e-13
Identities = 35/83 (42%), Positives = 56/83 (67%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+++ + + ++ K+IKEL+ K + KLT +++TGG FTITN G++ TPIINPP
Sbjct: 98 PVVKNAENKSLLELSKEIKELSEKARENKLTPDEITGGTFTITNLGMYEIDSFTPIINPP 157
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
+SAILG++ I P+ + + I
Sbjct: 158 ESAILGVNKIYKEPVVIEDNIVI 180
Score = 44.0 bits (99), Expect = 0.004
Identities = 18/36 (50%), Positives = 28/36 (77%)
Frame = +2
Query: 515 MYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
M L+LS+DHRLIDG + FL+ +K++LE+P +L+
Sbjct: 184 MKLSLSFDHRLIDGATAAKFLLDLKKILENPVSMLI 219
Score = 37.1 bits (82), Expect = 0.41
Identities = 20/74 (27%), Positives = 43/74 (58%)
Frame = +1
Query: 34 EVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNY 213
+V++ +++LR+ ++ E + + KA V ALK+ P +N SI+GD+++ +
Sbjct: 27 KVDVTELVNLRENLNKSGEHK----FTYTDLIAKACVIALKKNPVLNWSIEGDEIIKNPN 82
Query: 214 FDVSMAVSTPRGLV 255
++ +AV+ GL+
Sbjct: 83 INLGIAVALEDGLI 96
>UniRef50_Q73FZ4 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=9;
Rickettsiales|Rep: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Wolbachia pipientis wMel
Length = 454
Score = 78.2 bits (184), Expect = 2e-13
Identities = 35/84 (41%), Positives = 55/84 (65%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP++++ D G+ I K++K+L + GKL E+ GG FTI+N G+FG + IINP
Sbjct: 326 TPIVKNADKKGILSISKEVKDLVSRARSGKLKPEEFQGGGFTISNLGMFGIKAFSAIINP 385
Query: 435 PQSAILGMHAIKDRPMAVNGQVEI 506
PQS I+ + A K +P+ +N ++EI
Sbjct: 386 PQSCIMAVGASKKQPIVMNEKIEI 409
Score = 33.5 bits (73), Expect = 5.0
Identities = 12/42 (28%), Positives = 29/42 (69%)
Frame = +1
Query: 130 VKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLV 255
+KA ++K++P++N+S + ++ ++ D+S+AV+ GL+
Sbjct: 284 IKAAAFSMKKFPDINSSWIDNKILRYSNIDISIAVALEDGLI 325
Score = 32.7 bits (71), Expect = 8.8
Identities = 14/38 (36%), Positives = 22/38 (57%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
+M + LS DHR +DG FL K +E+P +L++
Sbjct: 412 IMTVTLSVDHRAVDGALGAKFLNAFKHYIENPLVMLIE 449
>UniRef50_Q9KES1 Cluster: Dihydrolipoamide S-acetyltransferase; n=1;
Bacillus halodurans|Rep: Dihydrolipoamide
S-acetyltransferase - Bacillus halodurans
Length = 436
Score = 77.8 bits (183), Expect = 2e-13
Identities = 33/83 (39%), Positives = 59/83 (71%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV++ VD G+A + + K +A+ D +L+ E ++GG FTI+N G++ + TP+IN P
Sbjct: 315 PVVKHVDKKGLAQLTNECKTVAMAARDNRLSQEMMSGGTFTISNLGMYAIDVFTPVINQP 374
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
+SAILG+ I+++P+ ++GQ+E+
Sbjct: 375 ESAILGVGRIQEKPVGIDGQIEL 397
Score = 54.0 bits (124), Expect = 3e-06
Identities = 27/83 (32%), Positives = 43/83 (51%)
Frame = +1
Query: 7 STAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID 186
S +T E++M + +R Q E+ G RL + +KAV AL +P +NAS
Sbjct: 231 SAPHVTITTEIDMSSTIKIRSQLLGMIEQETGYRLSYTEIVMKAVAHALMSHPTINASFF 290
Query: 187 GDDVVYHNYFDVSMAVSTPRGLV 255
+++VYH + +AV+ GLV
Sbjct: 291 ENEIVYHEDVHIGLAVAVEGGLV 313
Score = 46.4 bits (105), Expect = 7e-04
Identities = 19/38 (50%), Positives = 27/38 (71%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
PMM +LS+DHR+IDG + FL +K +LE P +LL+
Sbjct: 399 PMMTASLSFDHRVIDGAPAAAFLTDVKSMLEQPFQLLM 436
>UniRef50_Q67ME8 Cluster: Branched-chain alpha-keto acid
dehydrogenase E2; n=2; Bacilli|Rep: Branched-chain
alpha-keto acid dehydrogenase E2 - Symbiobacterium
thermophilum
Length = 459
Score = 77.0 bits (181), Expect = 4e-13
Identities = 34/85 (40%), Positives = 52/85 (61%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV++ D L +A + + + +LA + G+LT++D+TGG FT+ N G FGS +S PIIN P
Sbjct: 334 PVIKHADRLSIAGLNEAVADLAERARAGRLTLDDVTGGTFTVNNTGAFGSFLSAPIINYP 393
Query: 438 QSAILGMHAIKDRPMAVNGQVEILR 512
Q+AIL I P+ + +R
Sbjct: 394 QAAILSFEKITKMPVVLENDAIAIR 418
Score = 61.3 bits (142), Expect = 2e-08
Identities = 28/76 (36%), Positives = 49/76 (64%)
Frame = +1
Query: 25 TFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVY 204
T +V++ ++ LR+Q G F R G L ++ F++KAVVE+L+ YP +N+ +GD++V
Sbjct: 256 TMMQVDVTNLVKLREQAGPEFRARTGRPLSYVPFFIKAVVESLREYPILNSQWNGDEIVI 315
Query: 205 HNYFDVSMAVSTPRGL 252
++S+AV+T L
Sbjct: 316 RQDINISVAVATEDAL 331
>UniRef50_Q47KD8 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=1;
Thermobifida fusca YX|Rep: Pyruvate dehydrogenase
complex, E2 component, dihydrolipoamide
acetyltransferase - Thermobifida fusca (strain YX)
Length = 431
Score = 77.0 bits (181), Expect = 4e-13
Identities = 31/81 (38%), Positives = 57/81 (70%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PVL D DTL ++++ ++ + L K DGKL+ +D++GG F+++N G+FG + +INPP
Sbjct: 310 PVLHDADTLALSEVARRSRALVEKARDGKLSPQDMSGGTFSVSNLGMFGVESFSAVINPP 369
Query: 438 QSAILGMHAIKDRPMAVNGQV 500
++AIL + A++ P+ +G++
Sbjct: 370 EAAILAVGAMQQEPVVRDGEI 390
Score = 41.1 bits (92), Expect = 0.025
Identities = 22/73 (30%), Positives = 38/73 (52%)
Frame = +1
Query: 37 VNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYF 216
++ + + + R Q E G+++ VKAV L+ +PEVN+S D ++ H
Sbjct: 237 IDAEALREFRAQINEQLAPT-GVKVSVNDLIVKAVATVLRDHPEVNSSWVDDKLLRHKRI 295
Query: 217 DVSMAVSTPRGLV 255
+V +AV+ GLV
Sbjct: 296 NVGIAVAVDTGLV 308
Score = 36.7 bits (81), Expect = 0.54
Identities = 16/34 (47%), Positives = 21/34 (61%)
Frame = +2
Query: 521 LALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
L LS DHR +DG FL + E+LE P R++L
Sbjct: 398 LELSVDHRAVDGAVGAAFLKDLAEVLESPMRIVL 431
>UniRef50_A6DTS5 Cluster: Pyruvate dehydrogenase complex , E2
component, dihydrolipoamide acetyltransferase; n=1;
Lentisphaera araneosa HTCC2155|Rep: Pyruvate
dehydrogenase complex , E2 component, dihydrolipoamide
acetyltransferase - Lentisphaera araneosa HTCC2155
Length = 442
Score = 77.0 bits (181), Expect = 4e-13
Identities = 38/89 (42%), Positives = 57/89 (64%), Gaps = 1/89 (1%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMS-TPIIN 431
TP++R D+ G+A I K +K L K L+ E+ GG+FTI+N G+FG++ S T I+N
Sbjct: 319 TPIVRSADSKGLASISKDVKSLVGKARSNSLSPEEYQGGSFTISNLGMFGAVDSFTAILN 378
Query: 432 PPQSAILGMHAIKDRPMAVNGQVEILR*C 518
PPQSAIL + ++ VNG+V+ + C
Sbjct: 379 PPQSAILAVAGTQEELKLVNGEVKSAKVC 407
Score = 54.0 bits (124), Expect = 3e-06
Identities = 30/79 (37%), Positives = 44/79 (55%)
Frame = +1
Query: 19 LTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDV 198
LTT ++ M +MDLR Q G+R+ F VKA +L ++P +N + GD +
Sbjct: 246 LTT--KIEMDRLMDLRAQ----INSMEGVRISINDFIVKACGLSLAKFPAMNGAFQGDKI 299
Query: 199 VYHNYFDVSMAVSTPRGLV 255
V N D+S+AVS P GL+
Sbjct: 300 VQFNDVDISVAVSIPDGLI 318
Score = 32.7 bits (71), Expect = 8.8
Identities = 12/34 (35%), Positives = 23/34 (67%)
Frame = +2
Query: 521 LALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
+ ++ DHR+IDG + F+ +K+ LE P +L++
Sbjct: 409 MTITCDHRVIDGALAAEFMNALKDYLETPAKLIV 442
>UniRef50_Q1Q664 Cluster: Similar to 2-oxoglutarate dehydrogenase
complex E2 component; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similar to 2-oxoglutarate
dehydrogenase complex E2 component - Candidatus Kuenenia
stuttgartiensis
Length = 416
Score = 76.2 bits (179), Expect = 7e-13
Identities = 37/75 (49%), Positives = 50/75 (66%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV++D D M + ++I+E+AV KL +D+ GG FTITN GV GSL TP+I P
Sbjct: 278 PVIKDADKKDMFQLAREIQEIAVNARSKKLKPDDVRGGTFTITNYGVNGSLFGTPLILQP 337
Query: 438 QSAILGMHAIKDRPM 482
QSAILG+ A+ RP+
Sbjct: 338 QSAILGVGAVVKRPV 352
Score = 57.6 bits (133), Expect = 3e-07
Identities = 31/85 (36%), Positives = 51/85 (60%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+ + A++TT EV+M P+ R+ EA KR GI L ++ F AVV+ALK + +N+S
Sbjct: 193 RQTAALVTTVFEVDMTPVTKYRELNREAM-KREGIHLTYLPFIAFAVVQALKEHVALNSS 251
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
+ ++ NY ++ +AV+ GLV
Sbjct: 252 WTDNGILQKNYINLGIAVALEDGLV 276
Score = 38.7 bits (86), Expect = 0.13
Identities = 15/30 (50%), Positives = 24/30 (80%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLE 601
M+YL+LS+DHR++DG + FL +K++LE
Sbjct: 365 MVYLSLSFDHRVMDGAHADAFLHKVKDILE 394
>UniRef50_Q9RYB8 Cluster: 2-oxo acid dehydrogenase, E2 component;
n=2; Deinococcus|Rep: 2-oxo acid dehydrogenase, E2
component - Deinococcus radiodurans
Length = 525
Score = 75.8 bits (178), Expect = 1e-12
Identities = 34/75 (45%), Positives = 53/75 (70%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+RDVD + D+ + + +LA + GKL+ ++LTG +F++TN G G+L S PIIN P
Sbjct: 400 PVIRDVDRKSIFDLARDVVDLAGRANAGKLSPDELTGSSFSVTNIGSIGALFSFPIINVP 459
Query: 438 QSAILGMHAIKDRPM 482
+AI+G+H+I RP+
Sbjct: 460 DAAIMGVHSIVKRPI 474
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/83 (32%), Positives = 49/83 (59%), Gaps = 2/83 (2%)
Frame = +1
Query: 10 TAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID- 186
T T +EVN+ +++ R++ + K ++L ++ F KA+ ALK+YP +N S D
Sbjct: 316 TVRTLTVDEVNLTKLVEFRQRVKDE-AKAADVKLSYLPFIFKAITVALKKYPSLNTSFDE 374
Query: 187 -GDDVVYHNYFDVSMAVSTPRGL 252
++V +Y+++ MAV+T GL
Sbjct: 375 ATQEIVQKSYYNLGMAVATEAGL 397
Score = 50.0 bits (114), Expect = 5e-05
Identities = 22/38 (57%), Positives = 29/38 (76%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
MMYL+LS+DHRLIDG E+ F + LLE+P RL+L+
Sbjct: 486 MMYLSLSFDHRLIDGAEAARFCKEVIRLLENPDRLMLE 523
>UniRef50_Q0W153 Cluster: Pyruvate dehydrogenase complex E2,
dihydrolipoamide acetyltransferase; n=1; uncultured
methanogenic archaeon RC-I|Rep: Pyruvate dehydrogenase
complex E2, dihydrolipoamide acetyltransferase -
Uncultured methanogenic archaeon RC-I
Length = 428
Score = 75.8 bits (178), Expect = 1e-12
Identities = 37/79 (46%), Positives = 47/79 (59%)
Frame = +3
Query: 264 LRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPPQS 443
++D D + I ++IKEL GK+ VE L G FTI N G G L +TPIINPP+S
Sbjct: 306 VKDADRKSIVQISREIKELVELAESGKIGVEQLRGSTFTIANIGSIGGLFATPIINPPES 365
Query: 444 AILGMHAIKDRPMAVNGQV 500
AIL M I+D P +G V
Sbjct: 366 AILEMQQIRDMPRVCDGNV 384
Score = 67.3 bits (157), Expect = 3e-10
Identities = 30/84 (35%), Positives = 58/84 (69%), Gaps = 2/84 (2%)
Frame = +1
Query: 10 TAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDG 189
TA +T F++ ++ + +LR+Q A ++ G+++ +++F VKAV AL+ +P +NASID
Sbjct: 221 TAQVTVFDDADVTKLSELREQVNGA--RKDGVKVSYLAFTVKAVSAALRNHPVLNASIDD 278
Query: 190 D--DVVYHNYFDVSMAVSTPRGLV 255
+ ++V Y+++ +A+ TPRGL+
Sbjct: 279 EKGEIVLKKYYNIGLAIDTPRGLM 302
Score = 41.5 bits (93), Expect = 0.019
Identities = 19/39 (48%), Positives = 27/39 (69%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
+M L+L+ DHR+IDG E FL +K LEDP LL+++
Sbjct: 389 VMNLSLTIDHRIIDGAEGQRFLNEVKGYLEDPAALLVNM 427
>UniRef50_Q0SJA7 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=1; Rhodococcus sp. RHA1|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Rhodococcus sp. (strain RHA1)
Length = 367
Score = 75.4 bits (177), Expect = 1e-12
Identities = 38/85 (44%), Positives = 54/85 (63%), Gaps = 2/85 (2%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+RD LG+ + + I + A K G +T +DLTGG FT+TN G G+L TPIIN P
Sbjct: 241 PVIRDAQQLGIEGLAQAIADKADKVRTGTITADDLTGGTFTLTNTGSRGALFDTPIINQP 300
Query: 438 QSAILGMHAIKDR--PMAVNGQVEI 506
Q+ ILG+ A+ +R P +G++ I
Sbjct: 301 QTGILGVGAVVERLVPSRQDGELRI 325
Score = 62.1 bits (144), Expect = 1e-08
Identities = 32/85 (37%), Positives = 55/85 (64%), Gaps = 2/85 (2%)
Frame = +1
Query: 7 STAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID 186
+ A LTT EV++ I LR + +AF +R GI+L F+ F+ +A V+AL + +NAS++
Sbjct: 155 TAAQLTTVLEVDVTAIARLRATHKDAFLQRTGIKLSFLPFFAQAAVDALAEHRVLNASLN 214
Query: 187 GD--DVVYHNYFDVSMAVSTPRGLV 255
D +V Y+++ + MAV + +GL+
Sbjct: 215 TDVTEVTYYDHCHLGMAVDSAKGLM 239
Score = 42.3 bits (95), Expect = 0.011
Identities = 16/31 (51%), Positives = 24/31 (77%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLED 604
M YL++SYDHR++DG ++ FL T+K LE+
Sbjct: 330 MAYLSISYDHRIVDGADAARFLTTVKARLEN 360
>UniRef50_Q9YBC6 Cluster: Pyruvate dehydrogenase complex, E2
component; n=1; Aeropyrum pernix|Rep: Pyruvate
dehydrogenase complex, E2 component - Aeropyrum pernix
Length = 412
Score = 74.9 bits (176), Expect = 2e-12
Identities = 32/82 (39%), Positives = 58/82 (70%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+++V+ G+ I ++I +L K + +L++E+++G FTITN G GS++ P+I PP
Sbjct: 285 PVVKNVEKKGLFAIAREIADLTAKAREMRLSLEEVSGATFTITNVGSIGSVIGFPVIYPP 344
Query: 438 QSAILGMHAIKDRPMAVNGQVE 503
AILG+H + +RP+ V+G+++
Sbjct: 345 NVAILGVHRLVERPVYVDGELK 366
Score = 49.2 bits (112), Expect = 9e-05
Identities = 26/76 (34%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Frame = +1
Query: 34 EVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGD--DVVYH 207
EV+ + LR+ E++ G+RL ++ F KAV +A+++YP VN+ D + ++V
Sbjct: 209 EVDFTELSKLREALKRDAEEK-GVRLTYLPFVFKAVAKAIRKYPLVNSEFDEEKMEIVVK 267
Query: 208 NYFDVSMAVSTPRGLV 255
++ AV TP GLV
Sbjct: 268 KAVNIGFAVDTPHGLV 283
Score = 37.1 bits (82), Expect = 0.41
Identities = 14/36 (38%), Positives = 25/36 (69%)
Frame = +2
Query: 518 YLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
+++LS+DHR ++G + FL+ +K LLE+P L +
Sbjct: 372 FVSLSFDHRALEGAYATRFLMEVKRLLENPALLFAE 407
>UniRef50_Q49110 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=3; Mollicutes|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Mycoplasma
capricolum subsp. capricolum (strain California kid /
ATCC27343 / NCTC 10154)
Length = 438
Score = 74.9 bits (176), Expect = 2e-12
Identities = 36/82 (43%), Positives = 53/82 (64%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV++ D L + +I KI ELA K DGKLT ++T FT++N G G +TPIIN P
Sbjct: 317 PVIKGADHLSVFEIAIKISELANKAKDGKLTRAEMTEATFTVSNFGSVGLDYATPIINSP 376
Query: 438 QSAILGMHAIKDRPMAVNGQVE 503
+SAILG+ + P+ +NG+++
Sbjct: 377 ESAILGVGTMSQTPLYINGELQ 398
Score = 39.1 bits (87), Expect = 0.10
Identities = 17/54 (31%), Positives = 34/54 (62%), Gaps = 2/54 (3%)
Frame = +1
Query: 100 GIRLGFMSFYVKAVVEALKRYPEVNASID--GDDVVYHNYFDVSMAVSTPRGLV 255
GI+L +++F +KAV ++L+ P +N D + + + + ++ +AV TP GL+
Sbjct: 262 GIKLTYLAFIIKAVAKSLRDMPNINVRGDFANNKIQFMHNINIGIAVDTPNGLM 315
Score = 33.9 bits (74), Expect = 3.8
Identities = 13/37 (35%), Positives = 25/37 (67%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
+M L+++ DHR+IDG ++ FL+ +++ L P L +
Sbjct: 402 IMPLSMTCDHRIIDGADAGRFLIKVQDYLSKPVLLFM 438
>UniRef50_Q8AB01 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex;
n=8; Bacteroidetes|Rep: Lipoamide acyltransferase
component of branched-chain alpha-keto acid
dehydrogenase complex - Bacteroides thetaiotaomicron
Length = 456
Score = 74.5 bits (175), Expect = 2e-12
Identities = 36/77 (46%), Positives = 47/77 (61%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+ D D L + + I LA+K D KL +D+ GG FTITN G F SL TP+IN P
Sbjct: 334 PVVHDADHLNLNGLAVAIDSLALKARDNKLMPDDIDGGTFTITNFGTFKSLFGTPVINQP 393
Query: 438 QSAILGMHAIKDRPMAV 488
Q AILG+ I+ +P +
Sbjct: 394 QVAILGVGYIEKKPAVI 410
Score = 57.6 bits (133), Expect = 3e-07
Identities = 26/83 (31%), Positives = 51/83 (61%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
K + +T EV++ ++ R++ +AF +R G++L +M +AV +AL YP+VN S
Sbjct: 247 KKVSPHVTNVVEVDVTKLVRWREKNKDAFFRREGVKLTYMPVITEAVAKALAAYPQVNVS 306
Query: 181 IDGDDVVYHNYFDVSMAVSTPRG 249
+DG ++++ + ++ +AVS G
Sbjct: 307 VDGYNILFKKHINIGIAVSLNDG 329
Score = 35.9 bits (79), Expect = 0.94
Identities = 16/30 (53%), Positives = 21/30 (70%)
Frame = +2
Query: 515 MYLALSYDHRLIDGRESVGFLVTIKELLED 604
MYL+LSYDHR++DG FL I + LE+
Sbjct: 424 MYLSLSYDHRVVDGMLGGNFLHFIADYLEN 453
>UniRef50_Q9X6X2 Cluster: Lipoamide acyltransferase; n=3;
Cystobacterineae|Rep: Lipoamide acyltransferase -
Myxococcus xanthus
Length = 416
Score = 74.5 bits (175), Expect = 2e-12
Identities = 39/95 (41%), Positives = 55/95 (57%), Gaps = 3/95 (3%)
Frame = +3
Query: 231 GFYAARPG---TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVF 401
G AA P V++ D L +A++ ++ L D KL +E+LTGG FTI++ G
Sbjct: 280 GMAAATPDGLTVAVVKSADRLTLAELARETARLGAAARDRKLKMEELTGGTFTISSLGQS 339
Query: 402 GSLMSTPIINPPQSAILGMHAIKDRPMAVNGQVEI 506
G L +TPIIN P+ ILG+H +K RP V QV +
Sbjct: 340 GGLFATPIINHPEVGILGVHRLKKRPAVVGDQVVV 374
Score = 47.6 bits (108), Expect = 3e-04
Identities = 21/52 (40%), Positives = 34/52 (65%), Gaps = 2/52 (3%)
Frame = +1
Query: 103 IRLGFMSFYVKAVVEALKRYPEVNASID--GDDVVYHNYFDVSMAVSTPRGL 252
I+L ++ F +KA V ALK++P +NA+ D ++V F++ MA +TP GL
Sbjct: 238 IKLNYLPFIIKATVAALKKFPHLNANFDEASQELVVRGEFNIGMAAATPDGL 289
Score = 34.7 bits (76), Expect = 2.2
Identities = 18/37 (48%), Positives = 22/37 (59%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
MM L+LS DHR+IDG + F I + LE P L L
Sbjct: 377 MMNLSLSCDHRVIDGSVAADFTYEIIKYLEKPDLLFL 413
>UniRef50_A1SJ23 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=18; Actinomycetales|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Nocardioides sp. (strain BAA-499 / JS614)
Length = 597
Score = 74.5 bits (175), Expect = 2e-12
Identities = 35/79 (44%), Positives = 52/79 (65%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TPV++D L +A + KKI ++A + K+ ++L+GG FTITN G G+L TPI+N
Sbjct: 471 TPVIKDAGDLSIAGLAKKIADVAQRTRTNKIGPDELSGGTFTITNLGSVGALWDTPIVNK 530
Query: 435 PQSAILGMHAIKDRPMAVN 491
PQ AILG A+ RP+ ++
Sbjct: 531 PQVAILGPGAVVKRPVVID 549
Score = 40.3 bits (90), Expect = 0.044
Identities = 16/30 (53%), Positives = 24/30 (80%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLE 601
M+YLAL+YDH+L+DG ++ FL +K+ LE
Sbjct: 562 MVYLALTYDHQLVDGADAGRFLTDVKQRLE 591
>UniRef50_Q6PLQ2 Cluster: Dihydrolipoamide S-acetyltransferase; n=1;
Chlamydomonas reinhardtii|Rep: Dihydrolipoamide
S-acetyltransferase - Chlamydomonas reinhardtii
Length = 643
Score = 74.5 bits (175), Expect = 2e-12
Identities = 33/81 (40%), Positives = 53/81 (65%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP++R D G+ + ++++ LA+K D KL E+ TGG+FT++N G++G + IINP
Sbjct: 517 TPIVRAADVKGLLAVSREVRALALKAKDNKLKPEEFTGGSFTVSNLGMYGLTHFSAIINP 576
Query: 435 PQSAILGMHAIKDRPMAVNGQ 497
PQ+AIL + +R + V GQ
Sbjct: 577 PQAAILAVGGATERVVLVGGQ 597
>UniRef50_Q97Y19 Cluster: Dihydrolipoamide S-acetyltransferase,
carboxy-end; n=2; cellular organisms|Rep:
Dihydrolipoamide S-acetyltransferase, carboxy-end -
Sulfolobus solfataricus
Length = 177
Score = 74.5 bits (175), Expect = 2e-12
Identities = 36/83 (43%), Positives = 54/83 (65%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R+ DT + +I K+ ELA K + KL ++++GG FTI+N G++ TPIINPP
Sbjct: 53 PVIRNADTKPITEIAKESHELADKARENKLNPDEVSGGTFTISNLGMYDIDSFTPIINPP 112
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
Q+AILG+ I+ P+ V + I
Sbjct: 113 QTAILGVGRIRRAPVVVGDNISI 135
Score = 39.1 bits (87), Expect = 0.10
Identities = 15/35 (42%), Positives = 26/35 (74%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRL 616
+M+L+L++DHR++DG + FL + E+LED +L
Sbjct: 138 IMWLSLTFDHRVMDGHTAAKFLKELTEILEDENKL 172
Score = 34.7 bits (76), Expect = 2.2
Identities = 13/51 (25%), Positives = 31/51 (60%)
Frame = +1
Query: 103 IRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLV 255
+++ + VK V + L+ +P +NA+++GD + ++ +AV+ +GL+
Sbjct: 1 MKITYTDILVKVVAKLLRDHPYLNATLEGDQIKIIEEVNIGIAVALDQGLI 51
>UniRef50_Q6MPR6 Cluster: Pyruvate dehydrogenase E2; n=1;
Bdellovibrio bacteriovorus|Rep: Pyruvate dehydrogenase
E2 - Bdellovibrio bacteriovorus
Length = 543
Score = 74.1 bits (174), Expect = 3e-12
Identities = 36/97 (37%), Positives = 58/97 (59%), Gaps = 3/97 (3%)
Frame = +3
Query: 231 GFYAARPG---TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVF 401
GF A P PV+++ D + +I K+I +L+ + DGKL +++ G T+TN G
Sbjct: 407 GFAADTPNGLVVPVIKNADQKSILEISKEILDLSKRARDGKLKPDEMKGATITVTNIGSI 466
Query: 402 GSLMSTPIINPPQSAILGMHAIKDRPMAVNGQVEILR 512
G +TP+IN P+ AILGM+ I ++ + NGQV ++
Sbjct: 467 GGTYATPVINHPEVAILGMYKIDEKVVLKNGQVSAIK 503
Score = 52.8 bits (121), Expect = 8e-06
Identities = 26/80 (32%), Positives = 46/80 (57%), Gaps = 2/80 (2%)
Frame = +1
Query: 22 TTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID--GDD 195
T +E + ++ LR+ E EK +G ++ ++ +KA++ ++ +P NASID +
Sbjct: 339 TIMDEAKVDAMVALRESLKEHAEK-NGTKITYLPIIMKALIATIREFPMFNASIDDAAGE 397
Query: 196 VVYHNYFDVSMAVSTPRGLV 255
+VY YF++ A TP GLV
Sbjct: 398 IVYKKYFNLGFAADTPNGLV 417
>UniRef50_Q1AT73 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Rubrobacter xylanophilus
DSM 9941|Rep: Catalytic domain of components of various
dehydrogenase complexes - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 441
Score = 74.1 bits (174), Expect = 3e-12
Identities = 33/85 (38%), Positives = 53/85 (62%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV++D D G+ + ++I E+ + +L+ +D++GG FT+ N G GS++STPIIN P
Sbjct: 317 PVIKDADDYGIVGLARRIDEVVRRARQRRLSPDDVSGGTFTVNNPGALGSVVSTPIINHP 376
Query: 438 QSAILGMHAIKDRPMAVNGQVEILR 512
Q+AIL AI RP+ + +R
Sbjct: 377 QAAILSAEAIVKRPVVLEDDAIAVR 401
Score = 56.8 bits (131), Expect = 5e-07
Identities = 26/75 (34%), Positives = 44/75 (58%)
Frame = +1
Query: 25 TFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVY 204
T E ++ ++ LR+ E F +R G+ L ++ F V+AVVE+LK +P +N+ DGD +V
Sbjct: 238 TLVEADVSGLVGLREARKEEFRRREGVNLTYLPFVVRAVVESLKEHPVLNSVWDGDRIVL 297
Query: 205 HNYFDVSMAVSTPRG 249
++ +AV G
Sbjct: 298 RKRINIGIAVDLEEG 312
Score = 34.3 bits (75), Expect = 2.9
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPT 610
MM L +S+DHR++DG ++ FL +K LE T
Sbjct: 403 MMNLEVSFDHRILDGGAALRFLNAVKRRLESYT 435
>UniRef50_A6GB59 Cluster: Alpha keto acid dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=1;
Plesiocystis pacifica SIR-1|Rep: Alpha keto acid
dehydrogenase complex, E2 component, dihydrolipoamide
acetyltransferase - Plesiocystis pacifica SIR-1
Length = 435
Score = 74.1 bits (174), Expect = 3e-12
Identities = 35/84 (41%), Positives = 54/84 (64%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+ D D L + D+ +++K L G+L ++LTG FTIT+ G G +++TPI+N P
Sbjct: 310 PVIHDADMLSLLDLAREVKRLGEGAKTGRLARDELTGSTFTITSLGTIGGVLATPILNYP 369
Query: 438 QSAILGMHAIKDRPMAVNGQVEIL 509
+ ILG+HAI+ P+ VN EI+
Sbjct: 370 EVGILGVHAIRKVPV-VNDNDEIV 392
Score = 50.0 bits (114), Expect = 5e-05
Identities = 26/80 (32%), Positives = 48/80 (60%), Gaps = 2/80 (2%)
Frame = +1
Query: 22 TTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDD-- 195
T ++++ ++ LRKQ +A ++ G+ L ++ F +KAV ALKR+P VNA +D
Sbjct: 230 TYVEQIDVTKLVTLRKQAKKAAAEQ-GVSLSYLPFIIKAVCHALKRFPIVNAELDEAQKR 288
Query: 196 VVYHNYFDVSMAVSTPRGLV 255
+V + + +A +T +GL+
Sbjct: 289 IVLKKRYSIGVAAATDQGLM 308
Score = 43.6 bits (98), Expect = 0.005
Identities = 19/37 (51%), Positives = 26/37 (70%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
+M L++S DHR++DG E FL ++ LEDPT LLL
Sbjct: 396 IMNLSVSLDHRVVDGFEGASFLQEVRRYLEDPTLLLL 432
>UniRef50_Q5UYG4 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex; n=2;
Halobacteriaceae|Rep: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex - Haloarcula
marismortui (Halobacterium marismortui)
Length = 545
Score = 74.1 bits (174), Expect = 3e-12
Identities = 32/81 (39%), Positives = 55/81 (67%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+ DVD G+ ++ ++ +L + + + ++ GG FT+TN GV G ++PIIN P
Sbjct: 423 PVVNDVDGKGLVELAGEVNDLVGRARERDIERSEMQGGTFTVTNFGVIGGEYASPIINVP 482
Query: 438 QSAILGMHAIKDRPMAVNGQV 500
++AILG+ A+K+RP+A +G+V
Sbjct: 483 ETAILGIGALKERPVAEDGEV 503
Score = 48.8 bits (111), Expect = 1e-04
Identities = 21/39 (53%), Positives = 30/39 (76%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
P + L+L+ DHR+IDG ++ F+ T+KE L DPTRLLL+
Sbjct: 507 PTLPLSLAIDHRVIDGADAARFVNTLKEYLSDPTRLLLE 545
Score = 42.3 bits (95), Expect = 0.011
Identities = 22/80 (27%), Positives = 46/80 (57%), Gaps = 2/80 (2%)
Frame = +1
Query: 22 TTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID--GDD 195
T ++V + +++ R++ E+R + L + F VK V AL ++P +N ++D ++
Sbjct: 343 THHDQVVVSGLVEARERLAPLAEERD-VTLTYTPFVVKCVAAALDKHPVLNTALDTENEE 401
Query: 196 VVYHNYFDVSMAVSTPRGLV 255
+VY + ++ +A +T GLV
Sbjct: 402 IVYRDAHNIGVAAATDHGLV 421
>UniRef50_P37942 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex (EC
2.3.1.168) (Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase); n=37; Bacillales|Rep:
Lipoamide acyltransferase component of branched-chain
alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
(Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase) - Bacillus subtilis
Length = 424
Score = 73.7 bits (173), Expect = 4e-12
Identities = 38/84 (45%), Positives = 53/84 (63%), Gaps = 1/84 (1%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+++ D + I K I LA K DGKLT +D+ GG FT+ N G FGS+ S IIN P
Sbjct: 300 PVIKNADEKTIKGIAKDITGLAKKVRDGKLTADDMQGGTFTVNNTGSFGSVQSMGIINYP 359
Query: 438 QSAILGMHAIKDRPMAV-NGQVEI 506
Q+AIL + +I RP+ + NG + +
Sbjct: 360 QAAILQVESIVKRPVVMDNGMIAV 383
Score = 57.2 bits (132), Expect = 4e-07
Identities = 26/76 (34%), Positives = 46/76 (60%)
Frame = +1
Query: 25 TFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVY 204
T EV++ ++ R ++F+K G L F +F+VKAV +ALK +P++N+ GD ++
Sbjct: 222 TMMEVDVTNMVAYRNSIKDSFKKTEGFNLTFFAFFVKAVAQALKEFPQMNSMWAGDKIIQ 281
Query: 205 HNYFDVSMAVSTPRGL 252
++S+AV+T L
Sbjct: 282 KKDINISIAVATEDSL 297
>UniRef50_A7HHV9 Cluster: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase; n=4;
Proteobacteria|Rep: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase - Anaeromyxobacter
sp. Fw109-5
Length = 574
Score = 73.3 bits (172), Expect = 5e-12
Identities = 39/94 (41%), Positives = 56/94 (59%), Gaps = 3/94 (3%)
Frame = +3
Query: 210 LFRRQHGGFYAARPG---TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFT 380
L R H GF A PG PV++D D G+ +I +++ ELA K DGKL + D+ GG F+
Sbjct: 434 LKRYFHIGFAADTPGGLVVPVVKDADRKGVLEIARELAELAQKARDGKLQLADMQGGTFS 493
Query: 381 ITNGGVFGSLMSTPIINPPQSAILGMHAIKDRPM 482
+++ G G TPIIN P+ AILG+ +P+
Sbjct: 494 VSSLGGIGGTAFTPIINAPEVAILGVSRSATKPV 527
Score = 58.4 bits (135), Expect = 2e-07
Identities = 27/79 (34%), Positives = 47/79 (59%)
Frame = +1
Query: 19 LTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDV 198
+T +E ++ + R + + K G+++ ++F +KA V AL+R+PE N+S++GD +
Sbjct: 374 VTQHDEADITELERFRVELNQERAKE-GVKVTLLAFVLKACVAALRRFPEFNSSLEGDQL 432
Query: 199 VYHNYFDVSMAVSTPRGLV 255
V YF + A TP GLV
Sbjct: 433 VLKRYFHIGFAADTPGGLV 451
Score = 36.3 bits (80), Expect = 0.71
Identities = 16/37 (43%), Positives = 24/37 (64%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
M+ L+LSYDHR++DG + F + +LL D R +L
Sbjct: 538 MLPLSLSYDHRVVDGAAAARFTSHLAQLLADMRRAML 574
>UniRef50_A3HTS0 Cluster: 2-oxo acid dehydrogenases acyltransferase
(Catalytic domain) protein; n=2; Bacteroidetes|Rep:
2-oxo acid dehydrogenases acyltransferase (Catalytic
domain) protein - Algoriphagus sp. PR1
Length = 432
Score = 73.3 bits (172), Expect = 5e-12
Identities = 33/77 (42%), Positives = 50/77 (64%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R D L + I K++ +LA + + KL +DL+GG +T++N G FG++M TPII P
Sbjct: 306 PVIRKADQLNLVGISKQVNDLANRARNNKLNADDLSGGTYTVSNVGSFGNVMGTPIIMQP 365
Query: 438 QSAILGMHAIKDRPMAV 488
Q AI+ + AI +P V
Sbjct: 366 QVAIMAVGAIVKKPAVV 382
Score = 60.5 bits (140), Expect = 4e-08
Identities = 25/83 (30%), Positives = 53/83 (63%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
K ++A +T+F E +M I+ R++ +A+ ++ G + + F+++A+ +A++ +P +N S
Sbjct: 219 KKTSAHVTSFVEADMTNIVLWREKNKQAYREKFGESITYTPFFIEAIAKAIRDFPMINIS 278
Query: 181 IDGDDVVYHNYFDVSMAVSTPRG 249
IDGD ++ ++ MAV+ P G
Sbjct: 279 IDGDKIIKKKDINIGMAVALPSG 301
>UniRef50_Q3VZH8 Cluster: Biotin/lipoyl attachment:Catalytic domain
of components of various dehydrogenase complexes:E3
binding; n=2; Frankia|Rep: Biotin/lipoyl
attachment:Catalytic domain of components of various
dehydrogenase complexes:E3 binding - Frankia sp. EAN1pec
Length = 475
Score = 72.9 bits (171), Expect = 7e-12
Identities = 40/102 (39%), Positives = 57/102 (55%), Gaps = 3/102 (2%)
Frame = +3
Query: 216 RRQHGGFYAARPG---TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTIT 386
R H GF A P PV+RD A + ++ L G+LT +LTGG FT+
Sbjct: 335 RAVHLGFAAQTPRGLVVPVVRDAQGHTTASLAAEVTRLTAAARAGRLTPAELTGGTFTLN 394
Query: 387 NGGVFGSLMSTPIINPPQSAILGMHAIKDRPMAVNGQVEILR 512
N GVFG +TPI+N P+ A++G+ I RP AV+G++ + R
Sbjct: 395 NYGVFGVDGATPIVNHPEVAMIGIGRILPRPWAVDGELAVRR 436
Score = 35.5 bits (78), Expect = 1.2
Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 6/56 (10%)
Frame = +1
Query: 106 RLGFMSFYVKAVVEALKRYPEVNASI--DGD----DVVYHNYFDVSMAVSTPRGLV 255
R+G ++ + V AL+R+P++N+++ D D V H + A TPRGLV
Sbjct: 295 RIGVLALLARVCVAALRRFPDLNSTVVTDADGRATGVRQHRAVHLGFAAQTPRGLV 350
>UniRef50_A3WC78 Cluster: Pyruvate dehydrogenase E2 component; n=2;
Alphaproteobacteria|Rep: Pyruvate dehydrogenase E2
component - Erythrobacter sp. NAP1
Length = 463
Score = 72.9 bits (171), Expect = 7e-12
Identities = 34/83 (40%), Positives = 52/83 (62%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TPV+ + DT G+A I K++KELA K DGKL + GG +++N G+FG +INP
Sbjct: 341 TPVITEADTKGLAQISKEMKELAGKARDGKLQPHEYQGGTASLSNLGMFGIKQFDAVINP 400
Query: 435 PQSAILGMHAIKDRPMAVNGQVE 503
PQ IL + A + P ++G+++
Sbjct: 401 PQGMILAVGAGQQVPYVIDGEIK 423
Score = 51.2 bits (117), Expect = 2e-05
Identities = 24/74 (32%), Positives = 43/74 (58%)
Frame = +1
Query: 34 EVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNY 213
++ + P++ LRK+ + E G++L +KA+ AL R P+ N S GD + ++
Sbjct: 268 DIVLDPLLKLRKELNASLEP-DGVKLSVNDLLIKALARALIRVPQCNVSYHGDTMRKYSR 326
Query: 214 FDVSMAVSTPRGLV 255
D+S+AV+ P GL+
Sbjct: 327 ADISVAVAAPSGLI 340
Score = 35.9 bits (79), Expect = 0.94
Identities = 15/37 (40%), Positives = 25/37 (67%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
+++ + S+DHR IDG E + IK+L+E+P LL+
Sbjct: 427 VLHASGSFDHRAIDGAEGAQLMEAIKQLVENPMGLLV 463
>UniRef50_Q5KUY3 Cluster: Pyruvate dehydrogenase E2; n=2;
Geobacillus|Rep: Pyruvate dehydrogenase E2 - Geobacillus
kaustophilus
Length = 431
Score = 72.5 bits (170), Expect = 9e-12
Identities = 41/102 (40%), Positives = 56/102 (54%), Gaps = 3/102 (2%)
Frame = +3
Query: 210 LFRRQHGGFYAARPG---TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFT 380
L +R H G A PV+RD D + ++ +I EL+ K L +E+L G FT
Sbjct: 288 LKKRYHIGIATATKAGLVVPVIRDADQKSIRELAIEIAELSEKAHRQALRLEELQGSTFT 347
Query: 381 ITNGGVFGSLMSTPIINPPQSAILGMHAIKDRPMAVNGQVEI 506
IT+ G G +TPIIN P+ AI G HAIK RP+ V ++ I
Sbjct: 348 ITSTGAGGGWFATPIINYPEVAIFGAHAIKRRPVVVGDEIVI 389
Score = 53.2 bits (122), Expect = 6e-06
Identities = 27/81 (33%), Positives = 48/81 (59%), Gaps = 2/81 (2%)
Frame = +1
Query: 19 LTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGD-- 192
+T +EV++ ++++RK K I+L ++ F +KAV ALK+YP NAS+D +
Sbjct: 226 VTGMDEVDVTKLVEIRKNLASELAKEQ-IKLTYLPFIIKAVTRALKQYPMFNASLDEETN 284
Query: 193 DVVYHNYFDVSMAVSTPRGLV 255
++V + + +A +T GLV
Sbjct: 285 EIVLKKRYHIGIATATKAGLV 305
Score = 42.3 bits (95), Expect = 0.011
Identities = 19/39 (48%), Positives = 28/39 (71%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
MM ++L++DHR+IDG + F+ T+ LE+P LLLDV
Sbjct: 392 MMGMSLTFDHRVIDGEPAGRFMRTVAHYLENPEVLLLDV 430
>UniRef50_Q3CI28 Cluster: Biotin/lipoyl attachment:Catalytic domain
of components of various dehydrogenase complexes:E3
binding; n=2; Thermoanaerobacter ethanolicus|Rep:
Biotin/lipoyl attachment:Catalytic domain of components
of various dehydrogenase complexes:E3 binding -
Thermoanaerobacter ethanolicus ATCC 33223
Length = 382
Score = 72.5 bits (170), Expect = 9e-12
Identities = 33/83 (39%), Positives = 54/83 (65%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+++ D + ++ K IKEL+ + + KLT +++ G FTITN G++ TPIINPP
Sbjct: 261 PVVKEADKKSLLELSKNIKELSERARNNKLTPDEIIGSTFTITNLGMYEIDSFTPIINPP 320
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
+SAILG++ I P+ ++ + I
Sbjct: 321 ESAILGVNKIYKEPVVLDDNIVI 343
Score = 41.9 bits (94), Expect = 0.014
Identities = 18/34 (52%), Positives = 26/34 (76%)
Frame = +2
Query: 521 LALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
L+LS+DHRLIDG + FL+ +K+ LE+P LL+
Sbjct: 349 LSLSFDHRLIDGATAAKFLLDLKKTLENPLSLLI 382
Score = 34.3 bits (75), Expect = 2.9
Identities = 15/47 (31%), Positives = 29/47 (61%)
Frame = +1
Query: 115 FMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLV 255
+ KA V A+K+ P VN SI+G+ ++ ++ ++ +AV+ GL+
Sbjct: 213 YTDLIAKACVIAIKKNPVVNWSIEGEYIIKNSSINLGIAVALDNGLI 259
>UniRef50_A7BC27 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 448
Score = 72.5 bits (170), Expect = 9e-12
Identities = 41/102 (40%), Positives = 57/102 (55%), Gaps = 4/102 (3%)
Frame = +3
Query: 213 FRRQHGGFYAARPG---TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTI 383
F + H GF P PV+R LG+ + K LA DG L+ + L+GG FT+
Sbjct: 307 FEQVHLGFACDTPRGLLVPVIRSAQALGLKAFSDEAKRLAGGAIDGSLSPDFLSGGTFTV 366
Query: 384 TNGGVFGSLMSTPIINPPQSAILGMHAIKDRP-MAVNGQVEI 506
+N G FG TP+IN PQ+AILG+ AI RP +A +G + +
Sbjct: 367 SNIGSFGIETFTPVINLPQTAILGVGAITPRPTVAADGSIGV 408
Score = 35.5 bits (78), Expect = 1.2
Identities = 24/83 (28%), Positives = 35/83 (42%)
Frame = +1
Query: 7 STAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID 186
STA LT N I+ +RK+ A E ++ AV L +YP NA ++
Sbjct: 241 STAQLTLNTTANAAGILAMRKKVKNADEALGLNKITLNDLVCFAVSRTLLKYPVFNAHLE 300
Query: 187 GDDVVYHNYFDVSMAVSTPRGLV 255
+ + A TPRGL+
Sbjct: 301 DGVLTEFEQVHLGFACDTPRGLL 323
>UniRef50_Q749T6 Cluster: Pyruvate dehydrogenase complex E2
component, dihydrolipoamide acetyltransferase; n=4;
Geobacter|Rep: Pyruvate dehydrogenase complex E2
component, dihydrolipoamide acetyltransferase -
Geobacter sulfurreducens
Length = 392
Score = 72.1 bits (169), Expect = 1e-11
Identities = 32/83 (38%), Positives = 52/83 (62%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R+VD + ++ +++EL K + +T++++ G FT+TN G FG + +TP+IN P
Sbjct: 268 PVIRNVDAKSIIELASELQELGRKARERTITLDEMRGSTFTLTNFGHFGGVFATPVINWP 327
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
AILG I DRP GQ+ +
Sbjct: 328 DVAILGFGRIADRPWVHAGQIVV 350
Score = 57.6 bits (133), Expect = 3e-07
Identities = 29/87 (33%), Positives = 53/87 (60%), Gaps = 2/87 (2%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+ +TA +T E ++ + LR++ +A E+R G L F+ F++KAV AL+ +P +NA+
Sbjct: 181 QRNTAFVTGMEEADITELWHLREREQQAVEQR-GTHLTFLPFFIKAVQHALREHPYLNAA 239
Query: 181 ID--GDDVVYHNYFDVSMAVSTPRGLV 255
ID +++ ++ +AV TP GL+
Sbjct: 240 IDDVAGEIILKKHYHFGIAVETPDGLM 266
Score = 35.9 bits (79), Expect = 0.94
Identities = 14/35 (40%), Positives = 23/35 (65%)
Frame = +2
Query: 521 LALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
L+L++DHR+ DG ++ FL + LEDP L ++
Sbjct: 356 LSLTFDHRVTDGADAAQFLSKVVRYLEDPALLFIE 390
>UniRef50_Q4L6L6 Cluster: Branched-chain alpha-keto acid
dehydrogenase E2; n=3; Staphylococcus|Rep:
Branched-chain alpha-keto acid dehydrogenase E2 -
Staphylococcus haemolyticus (strain JCSC1435)
Length = 442
Score = 72.1 bits (169), Expect = 1e-11
Identities = 33/83 (39%), Positives = 54/83 (65%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV++ D + I ++I ELA+K + +L+ ED++GG FT+ N G FGS+ S IIN P
Sbjct: 318 PVIKHADEKSIKGIAREINELALKARNKQLSQEDMSGGTFTVNNTGTFGSVSSMGIINHP 377
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
Q+AIL + +I +P+ ++ + I
Sbjct: 378 QAAILQVESIVKKPVVIDDMIAI 400
Score = 57.6 bits (133), Expect = 3e-07
Identities = 25/68 (36%), Positives = 44/68 (64%)
Frame = +1
Query: 34 EVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNY 213
EV+ ++ R + +F++ G L F +F+VKAV EALK P +N+S DG++++ H
Sbjct: 243 EVDATNLVKTRNHHKNSFKENEGYNLTFFAFFVKAVAEALKSNPLLNSSWDGEEIILHKD 302
Query: 214 FDVSMAVS 237
++S+AV+
Sbjct: 303 INISIAVA 310
>UniRef50_Q18CC2 Cluster: E2 component of acetoin dehydrogenase
enzyme system; n=2; Clostridium difficile|Rep: E2
component of acetoin dehydrogenase enzyme system -
Clostridium difficile (strain 630)
Length = 348
Score = 72.1 bits (169), Expect = 1e-11
Identities = 37/83 (44%), Positives = 53/83 (63%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+++ + + +I K+ KELA K GKL D G FTI+N G++G TPIIN P
Sbjct: 227 PVVKNANKKSLKEIAKESKELAEKVKTGKLMPADQEGNTFTISNVGMYGITTFTPIINMP 286
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
SAILG+ A +D+ + VNG+ +I
Sbjct: 287 SSAILGVGATQDKFVPVNGEAKI 309
Score = 42.7 bits (96), Expect = 0.008
Identities = 19/38 (50%), Positives = 28/38 (73%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
P+M L+L+ DHR+IDG + FL +KELLE+P +L+
Sbjct: 311 PIMNLSLTSDHRVIDGTVAAKFLKDLKELLENPLSMLV 348
>UniRef50_A1SQ65 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Nocardioides sp.
JS614|Rep: Catalytic domain of components of various
dehydrogenase complexes - Nocardioides sp. (strain
BAA-499 / JS614)
Length = 427
Score = 72.1 bits (169), Expect = 1e-11
Identities = 32/82 (39%), Positives = 54/82 (65%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TPVLRDV +L + + K+++LA + +G+L ++L GG ++TN G++G IINP
Sbjct: 305 TPVLRDVTSLTVTAVAAKVQDLAARAREGRLKQDELEGGTISVTNLGMYGVEEFAAIINP 364
Query: 435 PQSAILGMHAIKDRPMAVNGQV 500
P +AIL + A+++ P+ +G V
Sbjct: 365 PHAAILAVGAVREEPVVEDGAV 386
Score = 38.7 bits (86), Expect = 0.13
Identities = 26/68 (38%), Positives = 35/68 (51%)
Frame = +1
Query: 52 IMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMA 231
++DLR + E E R + VKAV A R PE+N D V + DV++A
Sbjct: 241 LVDLRAELNEGAETRVSLN----DLVVKAVAAAHARVPEMNVVWTPDAVRSFSSVDVAVA 296
Query: 232 VSTPRGLV 255
V+T RGLV
Sbjct: 297 VATDRGLV 304
>UniRef50_A5MZI5 Cluster: PdhC; n=6; Clostridium|Rep: PdhC -
Clostridium kluyveri DSM 555
Length = 444
Score = 71.7 bits (168), Expect = 2e-11
Identities = 35/85 (41%), Positives = 54/85 (63%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV++D D G+ I ++ KE+ K L+ +D+TGG FTITN G+ G +PIIN P
Sbjct: 323 PVVKDTDIKGLKQIAEEFKEIVKKAKSNSLSPDDMTGGTFTITNLGMLGIDSFSPIINQP 382
Query: 438 QSAILGMHAIKDRPMAVNGQVEILR 512
+ AILG++ I D P+ V G+ +++
Sbjct: 383 EVAILGVNTIVDTPV-VEGEKIVVK 406
Score = 41.1 bits (92), Expect = 0.025
Identities = 18/50 (36%), Positives = 30/50 (60%)
Frame = +1
Query: 106 RLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLV 255
+L + F +K V ALK++P VN SI G + +Y ++ +AV+ GL+
Sbjct: 272 KLTYTDFLIKIVSAALKQFPLVNCSISGGKFILKDYVNMGVAVALDEGLI 321
Score = 41.1 bits (92), Expect = 0.025
Identities = 20/38 (52%), Positives = 25/38 (65%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
P+M L+L+ DHR IDG + FL IKE +E P LLL
Sbjct: 407 PLMKLSLTADHRAIDGAYAAKFLQKIKEYIEKPELLLL 444
>UniRef50_A2WZU5 Cluster: Putative uncharacterized protein; n=2; Oryza
sativa|Rep: Putative uncharacterized protein - Oryza
sativa subsp. indica (Rice)
Length = 1812
Score = 71.7 bits (168), Expect = 2e-11
Identities = 39/85 (45%), Positives = 52/85 (61%), Gaps = 3/85 (3%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITN-GGVFGSLMSTPIINP 434
PV+RD D G+ I +++K++A + D L ED GG FTI+N GG FG IINP
Sbjct: 1688 PVIRDADKKGLGTIAEEVKQVAQRARDNSLKPEDYEGGTFTISNLGGPFGIKQFCAIINP 1747
Query: 435 PQSAILGMHAIKDR--PMAVNGQVE 503
PQSAIL + + R P +V+GQ E
Sbjct: 1748 PQSAILAIGTAEKRVIPGSVDGQYE 1772
>UniRef50_O45279 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 337
Score = 71.7 bits (168), Expect = 2e-11
Identities = 36/84 (42%), Positives = 55/84 (65%), Gaps = 1/84 (1%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMS-TPIIN 431
TP++ + D LG+ I K+KEL+ + KL + GG+FTI+N G+FGS+ + T IIN
Sbjct: 199 TPIVENSDILGVLAISSKVKELSGLARESKLKPQQFQGGSFTISNLGMFGSVTNFTAIIN 258
Query: 432 PPQSAILGMHAIKDRPMAVNGQVE 503
PPQ AIL + + ++V+GQ+E
Sbjct: 259 PPQCAILTIGGTRSEVVSVDGQLE 282
Score = 33.9 bits (74), Expect = 3.8
Identities = 18/55 (32%), Positives = 29/55 (52%)
Frame = +1
Query: 91 KRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLV 255
K+ G + F +KA AL+ P VN + + + D+S+AV+TP GL+
Sbjct: 145 KKSGTAVSLNDFIIKAAALALRSVPTVNVRWTPEGIGLGSV-DISVAVATPTGLI 198
>UniRef50_P65634 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=12; Bacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Mycobacterium bovis
Length = 553
Score = 71.7 bits (168), Expect = 2e-11
Identities = 34/78 (43%), Positives = 49/78 (62%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
+PV+ D L +A + + I ++A + G L ++L+GG FTITN G G+L TPI+ P
Sbjct: 423 SPVIHDAGDLSLAGLARAIADIAARARSGNLKPDELSGGTFTITNIGSQGALFDTPILVP 482
Query: 435 PQSAILGMHAIKDRPMAV 488
PQ+A+LG AI RP V
Sbjct: 483 PQAAMLGTGAIVKRPRVV 500
Score = 68.1 bits (159), Expect = 2e-10
Identities = 34/85 (40%), Positives = 55/85 (64%), Gaps = 2/85 (2%)
Frame = +1
Query: 7 STAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID 186
+TA LT +EV+M I+ LR + AF +R G+ L F+ F+ KAV++ALK +P +NAS +
Sbjct: 338 ATAQLTQTHEVDMTKIVGLRARAKAAFAEREGVNLTFLPFFAKAVIDALKIHPNINASYN 397
Query: 187 GD--DVVYHNYFDVSMAVSTPRGLV 255
D ++ Y++ + AV T +GL+
Sbjct: 398 EDTKEITYYDAEHLGFAVDTEQGLL 422
Score = 40.7 bits (91), Expect = 0.033
Identities = 18/29 (62%), Positives = 22/29 (75%)
Frame = +2
Query: 518 YLALSYDHRLIDGRESVGFLVTIKELLED 604
YL L+YDHRLIDG ++ FL TIK LE+
Sbjct: 516 YLPLTYDHRLIDGADAGRFLTTIKHRLEE 544
>UniRef50_Q83G30 Cluster: Dihydrolipoamide succinyltransferase
component E2; n=2; Tropheryma whipplei|Rep:
Dihydrolipoamide succinyltransferase component E2 -
Tropheryma whipplei (strain Twist) (Whipple's bacillus)
Length = 461
Score = 71.3 bits (167), Expect = 2e-11
Identities = 32/83 (38%), Positives = 54/83 (65%)
Frame = +1
Query: 7 STAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID 186
+TA L+T EV++ I+D R E F++ G+ L + F + A V+AL++YP +N+ I
Sbjct: 252 NTAQLSTVIEVDLTRIVDYRNSIKEKFKEAEGVNLTVLPFIINATVQALRKYPVINSHIV 311
Query: 187 GDDVVYHNYFDVSMAVSTPRGLV 255
D +V+ +Y ++S+AV T RGL+
Sbjct: 312 DDQIVFPDYENISLAVDTERGLL 334
Score = 69.7 bits (163), Expect = 6e-11
Identities = 33/78 (42%), Positives = 51/78 (65%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TPV+++ + +A K + +LA + + KL+ ++LTGG FT+TN G G+L TP++
Sbjct: 335 TPVIKNAGDMTVAQFAKSVFDLARRARNNKLSPDELTGGTFTVTNTGSRGALFDTPVVFL 394
Query: 435 PQSAILGMHAIKDRPMAV 488
PQ AILG+ AI RP+ V
Sbjct: 395 PQLAILGIGAIARRPVIV 412
Score = 38.3 bits (85), Expect = 0.18
Identities = 17/28 (60%), Positives = 21/28 (75%)
Frame = +2
Query: 518 YLALSYDHRLIDGRESVGFLVTIKELLE 601
+ ALSYDHR+IDG ++ FL IK LLE
Sbjct: 428 FFALSYDHRVIDGADAARFLGYIKSLLE 455
>UniRef50_Q2S152 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvatedehydrogenase
complex; n=1; Salinibacter ruber DSM 13855|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvatedehydrogenase complex - Salinibacter ruber
(strain DSM 13855)
Length = 465
Score = 71.3 bits (167), Expect = 2e-11
Identities = 34/82 (41%), Positives = 51/82 (62%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TPV+RD D G++++ ++ + LA + D L E+ G FT +N G+FG T IINP
Sbjct: 343 TPVIRDADRKGLSELARETRALAERARDRDLEPEEFEGATFTTSNLGMFGIEEFTAIINP 402
Query: 435 PQSAILGMHAIKDRPMAVNGQV 500
P SAIL + I+D P+ +G+V
Sbjct: 403 PNSAILAIGEIRDTPVVEDGEV 424
Score = 40.7 bits (91), Expect = 0.033
Identities = 18/36 (50%), Positives = 24/36 (66%)
Frame = +2
Query: 515 MYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
M + LS DHR++DG + FL T+K LE+P LLL
Sbjct: 430 MKVTLSCDHRVVDGAKGAHFLDTVKSYLEEPMNLLL 465
>UniRef50_Q9HN75 Cluster: Dihydrolipoamide S-acetyltransferase; n=1;
Halobacterium salinarum|Rep: Dihydrolipoamide
S-acetyltransferase - Halobacterium salinarium
(Halobacterium halobium)
Length = 478
Score = 71.3 bits (167), Expect = 2e-11
Identities = 34/81 (41%), Positives = 50/81 (61%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+ VD M +I ++ +L + + + D+ GG FTITN G G +TPIIN P
Sbjct: 356 PVVEHVDQKSMLEISTEMNDLVEQARERSIAPADMDGGTFTITNFGAIGGEYATPIINYP 415
Query: 438 QSAILGMHAIKDRPMAVNGQV 500
++AILG+ AI +RP+A +G V
Sbjct: 416 ETAILGLGAIDERPVAEDGDV 436
Score = 41.1 bits (92), Expect = 0.025
Identities = 18/53 (33%), Positives = 35/53 (66%), Gaps = 2/53 (3%)
Frame = +1
Query: 103 IRLGFMSFYVKAVVEALKRYPEVNASI--DGDDVVYHNYFDVSMAVSTPRGLV 255
++L +M F +KAVV ALK +P +N+ + D +++ +++ +AV+T GL+
Sbjct: 302 VKLTYMPFVMKAVVAALKEFPVLNSELREDDEEIALKQDYNIGVAVATDAGLM 354
Score = 38.3 bits (85), Expect = 0.18
Identities = 18/35 (51%), Positives = 23/35 (65%)
Frame = +2
Query: 521 LALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
L+LS DHR+IDG E+ F + E L DP LLL+
Sbjct: 444 LSLSIDHRVIDGAEAAQFTNRVMEYLTDPELLLLE 478
>UniRef50_Q92BY1 Cluster: Lin1411 protein; n=15; Bacillales|Rep:
Lin1411 protein - Listeria innocua
Length = 416
Score = 70.9 bits (166), Expect = 3e-11
Identities = 33/83 (39%), Positives = 53/83 (63%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+++ D + I ++I ELA K +GKL+ D+ GG FT+ + G FGS+ S IIN P
Sbjct: 292 PVIKNADEKSIKGIAREISELAGKARNGKLSQADMEGGTFTVNSTGSFGSVQSMGIINHP 351
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
Q+AIL + +I RP+ ++ + +
Sbjct: 352 QAAILQVESIVKRPVIIDDMIAV 374
Score = 54.0 bits (124), Expect = 3e-06
Identities = 21/68 (30%), Positives = 44/68 (64%)
Frame = +1
Query: 34 EVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNY 213
EV+ ++ R ++F+K G L + +F++KAV +ALK +P++N++ GD ++ H
Sbjct: 217 EVDATGLVRYRNTVKDSFKKEEGYSLTYFAFFIKAVAQALKEFPQLNSTWAGDKIIEHAN 276
Query: 214 FDVSMAVS 237
++S+A++
Sbjct: 277 INISIAIA 284
>UniRef50_A5UTW4 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=5; Chloroflexi (class)|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Roseiflexus sp. RS-1
Length = 434
Score = 70.9 bits (166), Expect = 3e-11
Identities = 40/98 (40%), Positives = 55/98 (56%), Gaps = 3/98 (3%)
Frame = +3
Query: 213 FRRQHGGFYAARPG---TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTI 383
+RR H G A PVLRD D +A I + + +L + +L ++ GG FTI
Sbjct: 293 YRRIHIGIAVALDDGLIVPVLRDADEKSLAGIARALNDLTERARMRRLQPDETEGGTFTI 352
Query: 384 TNGGVFGSLMSTPIINPPQSAILGMHAIKDRPMAVNGQ 497
+N GV GSL +TPI+N QS ILG+ AI RP+ + Q
Sbjct: 353 SNHGVGGSLFATPILNRGQSGILGVGAIVKRPVVITHQ 390
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/31 (51%), Positives = 21/31 (67%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLE 601
PM YL+L++DHR DG + FL +KE LE
Sbjct: 399 PMCYLSLTFDHRACDGATADAFLAAVKETLE 429
>UniRef50_Q2S4D4 Cluster: 2-oxo acid dehydrogenases acyltransferase
(Catalytic domain) protein; n=1; Salinibacter ruber DSM
13855|Rep: 2-oxo acid dehydrogenases acyltransferase
(Catalytic domain) protein - Salinibacter ruber (strain
DSM 13855)
Length = 639
Score = 70.5 bits (165), Expect = 4e-11
Identities = 32/79 (40%), Positives = 55/79 (69%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
K ++A +T+F E ++ ++ LR+ EAF +R G++L + F+VKA VEAL+ +P +NAS
Sbjct: 424 KATSAHVTSFAEADVTGLVQLREANKEAFREREGVKLTYTPFFVKAAVEALREHPLLNAS 483
Query: 181 IDGDDVVYHNYFDVSMAVS 237
++GD +V + F V +AV+
Sbjct: 484 VEGDKIVIKHDFHVGIAVA 502
Score = 66.1 bits (154), Expect = 8e-10
Identities = 32/77 (41%), Positives = 47/77 (61%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R+ ++ + +K +A + + +L ++L GG FT+TN G GSLM TPIIN P
Sbjct: 511 PVIRNAGDYNVSGLARKAANVAERARNKELQPDELQGGTFTVTNIGSLGSLMGTPIINQP 570
Query: 438 QSAILGMHAIKDRPMAV 488
Q IL AI+ RP+ V
Sbjct: 571 QVGILATGAIQKRPVVV 587
Score = 37.1 bits (82), Expect = 0.41
Identities = 17/30 (56%), Positives = 20/30 (66%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLE 601
MMYL+LSYDHR+IDG FL + LE
Sbjct: 601 MMYLSLSYDHRIIDGAMGSSFLQRVVTELE 630
>UniRef50_Q0LRZ3 Cluster: Dihydrolipoamide acetyltransferase, long
form; n=1; Caulobacter sp. K31|Rep: Dihydrolipoamide
acetyltransferase, long form - Caulobacter sp. K31
Length = 415
Score = 70.5 bits (165), Expect = 4e-11
Identities = 34/81 (41%), Positives = 52/81 (64%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP++R D G+A I +++ LA + +G+L + GG+FTI+N G+FG + IINP
Sbjct: 293 TPIVRQADRRGLASISAEVRTLAARAREGRLEPAEFQGGSFTISNLGMFGVRAFSAIINP 352
Query: 435 PQSAILGMHAIKDRPMAVNGQ 497
PQS IL + A + RP+ V G+
Sbjct: 353 PQSCILAVGAAERRPV-VRGE 372
Score = 36.3 bits (80), Expect = 0.71
Identities = 16/37 (43%), Positives = 21/37 (56%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
+M LS DHR +DG +L K L+E P RL+L
Sbjct: 379 VMTCTLSVDHRAVDGVVGARYLAAFKSLIEQPLRLML 415
Score = 34.7 bits (76), Expect = 2.2
Identities = 16/49 (32%), Positives = 26/49 (53%)
Frame = +1
Query: 109 LGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLV 255
L +KA AL++ PE N + D ++ D+S+AV+T GL+
Sbjct: 244 LSLNDLVIKAAALALRQVPEANTAWTDDAIIQFQDVDISVAVATDGGLI 292
>UniRef50_Q9XYS5 Cluster: Dihydrolipoyl dehydrogenase-binding
protein; n=2; Ascaris suum|Rep: Dihydrolipoyl
dehydrogenase-binding protein - Ascaris suum (Pig
roundworm) (Ascaris lumbricoides)
Length = 368
Score = 70.5 bits (165), Expect = 4e-11
Identities = 33/69 (47%), Positives = 49/69 (71%), Gaps = 1/69 (1%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMS-TPIIN 431
TP++ DTLG++ I K++ELA K KLT+E+ GG FT++N G++GS+ T IIN
Sbjct: 236 TPIVFKADTLGVSQIGAKVRELAKKARANKLTLEEFQGGTFTVSNLGMYGSISHFTAIIN 295
Query: 432 PPQSAILGM 458
PPQ+AI+ +
Sbjct: 296 PPQAAIMAI 304
Score = 38.7 bits (86), Expect = 0.13
Identities = 20/55 (36%), Positives = 29/55 (52%)
Frame = +1
Query: 91 KRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLV 255
K+ GI + F +KA AL+ PE+N D D+S+AV+TP GL+
Sbjct: 181 KKEGISVSINDFIIKACACALRAVPELNVKWMKDHAEALPNVDISVAVATPAGLI 235
>UniRef50_Q67SE5 Cluster: Pyruvate dehydrogenase E2; n=1;
Symbiobacterium thermophilum|Rep: Pyruvate dehydrogenase
E2 - Symbiobacterium thermophilum
Length = 450
Score = 70.1 bits (164), Expect = 5e-11
Identities = 36/102 (35%), Positives = 58/102 (56%), Gaps = 3/102 (2%)
Frame = +3
Query: 210 LFRRQHGGFYAARPG---TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFT 380
L +R H GF PV++D D + I +++ +L +G +GKL +++ G FT
Sbjct: 307 LHKRYHIGFALDTDAGLLVPVIKDADRKPVFAIAQEMNDLIARGREGKLAPDEMRGSTFT 366
Query: 381 ITNGGVFGSLMSTPIINPPQSAILGMHAIKDRPMAVNGQVEI 506
I+N G G L TP+IN P+ AILG+ + RP+ +G++ I
Sbjct: 367 ISNQGSIGGLFFTPVINYPEVAILGIGKTQPRPVVRDGEIVI 408
Score = 64.1 bits (149), Expect = 3e-09
Identities = 35/87 (40%), Positives = 51/87 (58%), Gaps = 2/87 (2%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
K + +TT EV+M +M R Q E R GI+L FM F +KAVV AL+ +P +NAS
Sbjct: 239 KYTAPHVTTVEEVDMTELMAFRAQAKE-LAARKGIKLSFMPFIIKAVVAALREFPYLNAS 297
Query: 181 IDGD--DVVYHNYFDVSMAVSTPRGLV 255
ID + ++V H + + A+ T GL+
Sbjct: 298 IDDEAQEIVLHKRYHIGFALDTDAGLL 324
Score = 46.4 bits (105), Expect = 7e-04
Identities = 21/38 (55%), Positives = 28/38 (73%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
M +LALS+DHRLIDG + FL + ELL DPT L+++
Sbjct: 411 MAHLALSFDHRLIDGGMATRFLNRLAELLSDPTLLMME 448
>UniRef50_A0LLM2 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Syntrophobacter
fumaroxidans MPOB|Rep: Catalytic domain of components of
various dehydrogenase complexes - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 443
Score = 70.1 bits (164), Expect = 5e-11
Identities = 36/82 (43%), Positives = 52/82 (63%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+RDVD + ++ ++ ++A + GK E++TGG FT+TN G G TPIIN P
Sbjct: 316 PVIRDVDRKSVRELAVELLDVAERTRRGKAEREEMTGGTFTLTNIGALGGTAFTPIINHP 375
Query: 438 QSAILGMHAIKDRPMAVNGQVE 503
QSAILGM + +P+ V G +E
Sbjct: 376 QSAILGMGQARLQPV-VRGDLE 396
Score = 48.4 bits (110), Expect = 2e-04
Identities = 25/69 (36%), Positives = 42/69 (60%), Gaps = 2/69 (2%)
Frame = +1
Query: 55 MDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID--GDDVVYHNYFDVSM 228
+D ++ +A + G L + F +KA V ALK +P NASID +++V+ Y+++ +
Sbjct: 246 LDAFRRKHKAEIREAGGALNMIVFVLKAAVAALKAFPGFNASIDPEREEIVFKRYYNIGV 305
Query: 229 AVSTPRGLV 255
AV T RGL+
Sbjct: 306 AVDTDRGLI 314
Score = 37.9 bits (84), Expect = 0.23
Identities = 16/37 (43%), Positives = 26/37 (70%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
++ L +++DHR++DG ++ FL I E LE+P LLL
Sbjct: 405 LLPLIVAFDHRIVDGADAARFLGMIIEALENPEELLL 441
>UniRef50_Q6KH63 Cluster: Pyruvate dehydrogenase E2 component
dihydrolipoamide acetyltransferase; n=6; Mycoplasma|Rep:
Pyruvate dehydrogenase E2 component dihydrolipoamide
acetyltransferase - Mycoplasma mobile
Length = 453
Score = 69.7 bits (163), Expect = 6e-11
Identities = 35/82 (42%), Positives = 49/82 (59%), Gaps = 1/82 (1%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+++ D L + +I K+I LAV D K+ ++L G +FT+TN GSL P+IN P
Sbjct: 331 PVIKNADKLNIIEIAKEITRLAVAARDKKIKADELKGSDFTVTNYASVGSLFGIPVINYP 390
Query: 438 QSAILGMHAIKDRPMAV-NGQV 500
AI G+ IKD P+ NG V
Sbjct: 391 DMAIAGIGVIKDEPIVTKNGIV 412
Score = 51.6 bits (118), Expect = 2e-05
Identities = 24/86 (27%), Positives = 49/86 (56%), Gaps = 2/86 (2%)
Frame = +1
Query: 4 NSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASI 183
++ A NE+N+ ++ LR++ ++ + G+++ F+ F +KA+ ALK +P + A
Sbjct: 244 SNVAYTNLVNEINVGSLVSLREKIKDSVQDLTGVKVTFLPFIIKAITLALKEFPVLMAKY 303
Query: 184 D--GDDVVYHNYFDVSMAVSTPRGLV 255
D ++VY ++ +AV T GL+
Sbjct: 304 DEQASELVYSGTLNIGIAVDTEAGLM 329
>UniRef50_O32959 Cluster: Dihydrolipoamide succinyltransferase; n=1;
Mycobacterium leprae|Rep: Dihydrolipoamide
succinyltransferase - Mycobacterium leprae
Length = 530
Score = 69.7 bits (163), Expect = 6e-11
Identities = 34/78 (43%), Positives = 49/78 (62%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
+PV+ L +A + + I ++A + G L E+L+GG FTITN G G+L TPI+ P
Sbjct: 400 SPVIHYAGDLSLAGLARAIVDIAARARSGNLKPEELSGGTFTITNIGSQGALFDTPILVP 459
Query: 435 PQSAILGMHAIKDRPMAV 488
PQ+A+LG+ AI RP V
Sbjct: 460 PQAAMLGIGAIVKRPRVV 477
Score = 64.9 bits (151), Expect = 2e-09
Identities = 32/85 (37%), Positives = 53/85 (62%), Gaps = 2/85 (2%)
Frame = +1
Query: 7 STAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID 186
+TA LT +EV+M I+ LR + AF +R G+ L F+ F KA ++ALK +P +NAS +
Sbjct: 315 ATAQLTQTHEVDMAKIVGLRAKAKAAFAEREGVNLTFLPFIAKAAIDALKIHPNINASYN 374
Query: 187 GD--DVVYHNYFDVSMAVSTPRGLV 255
D ++ Y++ + A+ T +GL+
Sbjct: 375 EDTKEITYYDAEHLGFAIDTDKGLL 399
Score = 40.7 bits (91), Expect = 0.033
Identities = 18/29 (62%), Positives = 22/29 (75%)
Frame = +2
Query: 518 YLALSYDHRLIDGRESVGFLVTIKELLED 604
YL L+YDHRLIDG ++ FL TIK LE+
Sbjct: 493 YLPLTYDHRLIDGADAGRFLTTIKHRLEE 521
>UniRef50_A6UGY8 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=3; Alphaproteobacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Sinorhizobium medicae WSM419
Length = 386
Score = 69.7 bits (163), Expect = 6e-11
Identities = 35/74 (47%), Positives = 49/74 (66%), Gaps = 1/74 (1%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTP-IINP 434
PV+R L +A+I +I++L + L+ D+TGG FTI+N GV GSL++TP IIN
Sbjct: 255 PVIRRAQNLSLAEIAARIQDLTTRARSNALSPADVTGGTFTISNHGVSGSLLATPIIINQ 314
Query: 435 PQSAILGMHAIKDR 476
PQSAILG+ + R
Sbjct: 315 PQSAILGVGKLDKR 328
>UniRef50_A1UIB1 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=4; Actinomycetales|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Mycobacterium sp. (strain KMS)
Length = 629
Score = 69.7 bits (163), Expect = 6e-11
Identities = 32/78 (41%), Positives = 50/78 (64%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
+PV+++ L +A + + I ++A + G L ++L+GG FTITN G G+L TPI+ P
Sbjct: 499 SPVIKNAGDLSLAGLARAIADIAARARSGDLKPDELSGGTFTITNIGSQGALFDTPILVP 558
Query: 435 PQSAILGMHAIKDRPMAV 488
PQ+A+LG AI RP +
Sbjct: 559 PQAAMLGTGAIVKRPRVI 576
Score = 63.7 bits (148), Expect = 4e-09
Identities = 32/85 (37%), Positives = 54/85 (63%), Gaps = 2/85 (2%)
Frame = +1
Query: 7 STAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID 186
+TA LT +EV+M I+ LR + F +R G+ L ++ F +AV++ALK++P VNAS +
Sbjct: 414 ATAQLTQTHEVDMTKIVALRAKAKNDFAEREGVNLTYLPFIARAVIDALKQHPNVNASYN 473
Query: 187 GD--DVVYHNYFDVSMAVSTPRGLV 255
D ++ Y++ + AV T +GL+
Sbjct: 474 EDTKEITYYDAEHLGFAVDTDQGLL 498
Score = 40.7 bits (91), Expect = 0.033
Identities = 18/29 (62%), Positives = 22/29 (75%)
Frame = +2
Query: 518 YLALSYDHRLIDGRESVGFLVTIKELLED 604
YL L+YDHRLIDG ++ FL TIK LE+
Sbjct: 592 YLPLTYDHRLIDGADAGRFLTTIKRRLEE 620
>UniRef50_Q2JA39 Cluster: Dehydrogenase subunit; n=4;
Actinomycetales|Rep: Dehydrogenase subunit - Frankia sp.
(strain CcI3)
Length = 430
Score = 69.3 bits (162), Expect = 8e-11
Identities = 40/99 (40%), Positives = 55/99 (55%), Gaps = 3/99 (3%)
Frame = +3
Query: 225 HGGFYAARPG---TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGG 395
H GF A P PV+ L A + +I L G LT +LTGG FT+ N G
Sbjct: 293 HLGFAAQTPRGLVVPVVHHAQGLTTARLAAEIARLTAAARAGTLTPAELTGGTFTLNNYG 352
Query: 396 VFGSLMSTPIINPPQSAILGMHAIKDRPMAVNGQVEILR 512
VFG STPII+ P++A++G+ I RP AV+G++ + R
Sbjct: 353 VFGVDGSTPIIHHPEAAMIGIGRIVPRPWAVDGELAVRR 391
Score = 33.9 bits (74), Expect = 3.8
Identities = 14/36 (38%), Positives = 24/36 (66%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLL 619
++ L+ ++DHR+ DG + FL + + +EDPT LL
Sbjct: 392 IVQLSFTFDHRVCDGATAGSFLRFVADAVEDPTVLL 427
Score = 33.1 bits (72), Expect = 6.6
Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 6/56 (10%)
Frame = +1
Query: 106 RLGFMSFYVKAVVEALKRYPEVNASI--DGD----DVVYHNYFDVSMAVSTPRGLV 255
R+G ++ + V AL R+P +N+++ D D V +H + A TPRGLV
Sbjct: 250 RIGLLAILARICVAALVRFPALNSAVVTDADGRATGVRHHAAVHLGFAAQTPRGLV 305
>UniRef50_Q5KIM3 Cluster: Dihydrolipoyllysine-residue
acetyltransferase, putative; n=2; Basidiomycota|Rep:
Dihydrolipoyllysine-residue acetyltransferase, putative
- Cryptococcus neoformans (Filobasidiella neoformans)
Length = 479
Score = 69.3 bits (162), Expect = 8e-11
Identities = 34/68 (50%), Positives = 45/68 (66%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP+++DV G+A I + K LA + DGKL E+ GG+FTI+N G+FG T IINP
Sbjct: 354 TPIIKDVGAKGLATISAETKALASRARDGKLKPEEYQGGSFTISNLGMFGVDEFTAIINP 413
Query: 435 PQSAILGM 458
PQS IL +
Sbjct: 414 PQSCILAV 421
Score = 46.8 bits (106), Expect = 5e-04
Identities = 26/74 (35%), Positives = 42/74 (56%)
Frame = +1
Query: 34 EVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNY 213
EVNM ++ LR+ + +A E + +L F VKA AL PE N++ G+ + +
Sbjct: 282 EVNMDRVLKLREVFNKAGESK--TKLSVNDFIVKAASLALADVPEANSAWLGETIRTYKK 339
Query: 214 FDVSMAVSTPRGLV 255
D+ +AV+TP GL+
Sbjct: 340 ADICVAVATPNGLI 353
>UniRef50_Q1IIF0 Cluster: Dihydrolipoamide S-succinyltransferase;
n=2; Acidobacteria|Rep: Dihydrolipoamide
S-succinyltransferase - Acidobacteria bacterium (strain
Ellin345)
Length = 555
Score = 68.9 bits (161), Expect = 1e-10
Identities = 34/77 (44%), Positives = 46/77 (59%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV++ D L +++ I +L + KL ED+ GG FTITN G+FG+ PII+ P
Sbjct: 429 PVVKQADGLSFVGLQRAITDLGERARAKKLKPEDVQGGTFTITNPGIFGAKFGMPIISQP 488
Query: 438 QSAILGMHAIKDRPMAV 488
Q AILG+ AI PM V
Sbjct: 489 QLAILGIGAITKVPMVV 505
Score = 58.8 bits (136), Expect = 1e-07
Identities = 26/85 (30%), Positives = 54/85 (63%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
K ++A + EV+ I+ LR++ +F+++ G++L + FY +AV AL+ +P +NAS
Sbjct: 343 KRTSAHVHGVFEVDFTKIVKLREKNKNSFQEKTGLKLTYTPFYARAVAHALRAWPIINAS 402
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
++G+++ Y ++ +AV+ GL+
Sbjct: 403 VEGENIHYKKDINLGIAVALDWGLI 427
>UniRef50_Q2GI07 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=6;
Anaplasmataceae|Rep: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Ehrlichia chaffeensis (strain Arkansas)
Length = 416
Score = 68.5 bits (160), Expect = 1e-10
Identities = 32/82 (39%), Positives = 48/82 (58%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP++ D + +I +++K LA K GKL E+ GG FT++N G+FG I+NP
Sbjct: 294 TPIIFGADKKSLLEISREVKALASKAKSGKLKPEEFQGGGFTVSNLGMFGIKEFYAIVNP 353
Query: 435 PQSAILGMHAIKDRPMAVNGQV 500
PQS I+ + + R M VN Q+
Sbjct: 354 PQSCIMSVGCSEKRAMVVNEQI 375
Score = 42.7 bits (96), Expect = 0.008
Identities = 18/44 (40%), Positives = 28/44 (63%)
Frame = +1
Query: 124 FYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLV 255
F +KAV ++K++PE+N S D +V D+S+AVS GL+
Sbjct: 250 FIIKAVAMSIKKFPEINVSWSDDKIVVFPSIDISVAVSIDNGLI 293
>UniRef50_Q92HK7 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=10; Rickettsia|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Rickettsia conorii
Length = 412
Score = 68.5 bits (160), Expect = 1e-10
Identities = 32/84 (38%), Positives = 51/84 (60%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP++++ + + ++ +++K L K D KLT E+ GG FTI+N G++G IINP
Sbjct: 290 TPIVKNANQKNILELSREMKALIKKAKDNKLTPEEFQGGGFTISNLGMYGIKNFNAIINP 349
Query: 435 PQSAILGMHAIKDRPMAVNGQVEI 506
PQS I+G+ A R + N Q+ I
Sbjct: 350 PQSCIMGVGASAKRAIVKNDQITI 373
Score = 52.8 bits (121), Expect = 8e-06
Identities = 25/74 (33%), Positives = 41/74 (55%)
Frame = +1
Query: 34 EVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNY 213
E N+ ++D+R+ + F + R+ F + AV +AL+ P NAS D + Y+N
Sbjct: 216 ECNVDKLLDIREDINKFFSEDKSTRISVNDFIILAVAKALQEVPNANASWGEDAIRYYNN 275
Query: 214 FDVSMAVSTPRGLV 255
D+S+AV+ GLV
Sbjct: 276 VDISVAVAIENGLV 289
Score = 36.3 bits (80), Expect = 0.71
Identities = 15/37 (40%), Positives = 23/37 (62%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
+M + LS DHR++DG FLV K+ +E P +L+
Sbjct: 376 IMDVTLSADHRVVDGAVGAEFLVAFKKFIESPVLMLI 412
>UniRef50_Q39ET0 Cluster: Dihydrolipoamide acetyltransferase; n=42;
Bacteria|Rep: Dihydrolipoamide acetyltransferase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 548
Score = 68.1 bits (159), Expect = 2e-10
Identities = 32/79 (40%), Positives = 50/79 (63%)
Frame = +1
Query: 19 LTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDV 198
+T +E ++ + LR Q + EK G++ ++F +KAVV ALK++P NAS+DGD++
Sbjct: 348 VTNNDEADITELEALRVQLNKEHEKA-GVKFTMLAFVIKAVVAALKKFPTFNASLDGDNL 406
Query: 199 VYHNYFDVSMAVSTPRGLV 255
V+ Y+ V A TP GLV
Sbjct: 407 VFKQYYHVGFAADTPNGLV 425
Score = 68.1 bits (159), Expect = 2e-10
Identities = 37/89 (41%), Positives = 52/89 (58%), Gaps = 3/89 (3%)
Frame = +3
Query: 225 HGGFYAARPG---TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGG 395
H GF A P PV+RD D G+ DI K++ EL+ DGKL + + GG F+I++ G
Sbjct: 413 HVGFAADTPNGLVVPVIRDADKKGLVDIAKEMAELSKAARDGKLKPDQMQGGCFSISSLG 472
Query: 396 VFGSLMSTPIINPPQSAILGMHAIKDRPM 482
G TPIIN P+ AILG+ + +P+
Sbjct: 473 GIGGTNFTPIINAPEVAILGLSRGQMKPV 501
Score = 36.3 bits (80), Expect = 0.71
Identities = 17/34 (50%), Positives = 23/34 (67%)
Frame = +2
Query: 521 LALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
L+LSYDHR+IDG E+ F + LL D R++L
Sbjct: 515 LSLSYDHRVIDGAEAARFNAYLGALLADFRRIIL 548
>UniRef50_Q65MC9 Cluster: AcoC; n=1; Bacillus licheniformis ATCC
14580|Rep: AcoC - Bacillus licheniformis (strain DSM 13
/ ATCC 14580)
Length = 377
Score = 67.7 bits (158), Expect = 3e-10
Identities = 36/99 (36%), Positives = 56/99 (56%), Gaps = 3/99 (3%)
Frame = +3
Query: 213 FRRQHGGFYAARP---GTPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTI 383
F H G AA PV+R + L + ++ KKIK A K +G+L +++ G FTI
Sbjct: 238 FEHVHLGVAAALDEGLAVPVIRHAERLPLIELAKKIKWYAKKAREGRLLHDEIEGSTFTI 297
Query: 384 TNGGVFGSLMSTPIINPPQSAILGMHAIKDRPMAVNGQV 500
TN G +G TPI+NPP++ ILG+ + P+ +G++
Sbjct: 298 TNLGAYGVEHFTPILNPPETGILGVGQMYSAPVYQDGEL 336
Score = 39.9 bits (89), Expect = 0.058
Identities = 16/34 (47%), Positives = 23/34 (67%)
Frame = +2
Query: 521 LALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
L+L++DHR +DG + FL +K LEDP +LL
Sbjct: 344 LSLTFDHRALDGAPAAAFLSDVKNYLEDPASILL 377
>UniRef50_A3U7C0 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-ketoacid dehydrogenase complex;
n=1; Croceibacter atlanticus HTCC2559|Rep: Lipoamide
acyltransferase component of branched-chain
alpha-ketoacid dehydrogenase complex - Croceibacter
atlanticus HTCC2559
Length = 480
Score = 67.7 bits (158), Expect = 3e-10
Identities = 31/77 (40%), Positives = 46/77 (59%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV++D D + ++ + +A + KL +D+ G FTI+N G FGS+M TPIIN P
Sbjct: 354 PVVKDADKKNLQELATDVNRMANLARENKLGGDDIKGSTFTISNVGTFGSVMGTPIINQP 413
Query: 438 QSAILGMHAIKDRPMAV 488
++AIL IK RP +
Sbjct: 414 EAAILATGIIKKRPEVI 430
Score = 56.4 bits (130), Expect = 6e-07
Identities = 24/83 (28%), Positives = 48/83 (57%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
K+++ +T + E +M I++ R F++ +G +L F +V+AV A+ +P +N S
Sbjct: 267 KHTSPHVTAYVEADMTDIVNWRNANKVKFQETYGEKLTFTPLFVEAVANAITEFPMINVS 326
Query: 181 IDGDDVVYHNYFDVSMAVSTPRG 249
+DG +++ + +V MA + P G
Sbjct: 327 VDGRNIIVKEHINVGMATALPSG 349
Score = 35.5 bits (78), Expect = 1.2
Identities = 16/30 (53%), Positives = 21/30 (70%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLE 601
MMYL+LS+DHR++DG FL I + LE
Sbjct: 443 MMYLSLSFDHRIVDGFLGGSFLKKIADNLE 472
>UniRef50_Q8YDW4 Cluster: DIHYDROLIPOAMIDE ACETYLTRANSFERASE
COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX; n=11;
Proteobacteria|Rep: DIHYDROLIPOAMIDE ACETYLTRANSFERASE
COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX - Brucella
melitensis
Length = 421
Score = 67.3 bits (157), Expect = 3e-10
Identities = 31/82 (37%), Positives = 51/82 (62%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP++R D + + I ++K LA + + +L E+ GG F+I+N ++G + IINP
Sbjct: 299 TPIIRSADQMSLGAISAQMKSLAARARENRLKPEEFQGGGFSISNLSMYGVKSFSAIINP 358
Query: 435 PQSAILGMHAIKDRPMAVNGQV 500
PQSAIL + A + RP+ NG++
Sbjct: 359 PQSAILAVGAGERRPIERNGEL 380
Score = 35.1 bits (77), Expect = 1.6
Identities = 19/57 (33%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Frame = +1
Query: 88 EKRHG-IRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLV 255
EKR G R+ F +KA AL+R P+ N + ++ D+++AV+T GL+
Sbjct: 242 EKREGSARISVNDFVIKASAAALRRVPDANVIWTDEALLKLKDVDIAVAVATEGGLI 298
Score = 33.9 bits (74), Expect = 3.8
Identities = 16/37 (43%), Positives = 20/37 (54%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
MM + LS DHR +DG L K +EDP LL+
Sbjct: 385 MMSVTLSVDHRAVDGALGAQLLAAFKAGIEDPMSLLV 421
>UniRef50_Q3JBP0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex dihydrolipoamide acyltransferase (E2) component
and related enzymes; n=1; Nitrosococcus oceani ATCC
19707|Rep: Pyruvate/2-oxoglutarate dehydrogenase complex
dihydrolipoamide acyltransferase (E2) component and
related enzymes - Nitrosococcus oceani (strain ATCC
19707 / NCIMB 11848)
Length = 447
Score = 67.3 bits (157), Expect = 3e-10
Identities = 33/82 (40%), Positives = 49/82 (59%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R+ D +A + ++ ELA K K+ E++ GG+FTITN G G TPIIN P
Sbjct: 324 PVIREADQKNIAQLAVELTELAEKARSRKIGPEEMAGGSFTITNLGGLGGSYFTPIINWP 383
Query: 438 QSAILGMHAIKDRPMAVNGQVE 503
+ AILG+ K P+ + G+ +
Sbjct: 384 EVAILGLSRAKMAPLYIEGEFQ 405
Score = 44.0 bits (99), Expect = 0.004
Identities = 21/38 (55%), Positives = 28/38 (73%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
++ L+LSYDHR+IDG ++V FL I E LEDP L L+
Sbjct: 409 LLPLSLSYDHRVIDGADAVRFLRWIVEALEDPLLLSLE 446
>UniRef50_Q7D716 Cluster: 2-oxoisovalerate dehydrogenase E2
component, dihydrolipoamide acetyltransferase, putative;
n=13; Mycobacterium|Rep: 2-oxoisovalerate dehydrogenase
E2 component, dihydrolipoamide acetyltransferase,
putative - Mycobacterium tuberculosis
Length = 393
Score = 67.3 bits (157), Expect = 3e-10
Identities = 37/98 (37%), Positives = 52/98 (53%), Gaps = 3/98 (3%)
Frame = +3
Query: 216 RRQHGGFYAARPG---TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTIT 386
R H GF AA PV+ D ++ ++ EL +G LT +L G FT++
Sbjct: 253 RGVHLGFGAATERGLLVPVVTDAQDKNTRELASRVAELITGAREGTLTPAELRGSTFTVS 312
Query: 387 NGGVFGSLMSTPIINPPQSAILGMHAIKDRPMAVNGQV 500
N G G P+IN P++AILG+ AIK RP+ V G+V
Sbjct: 313 NFGALGVDDGVPVINHPEAAILGLGAIKPRPVVVGGEV 350
Score = 39.1 bits (87), Expect = 0.10
Identities = 15/40 (37%), Positives = 25/40 (62%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
P M L +DHR++DG + F+ +++L+E P LLD+
Sbjct: 354 PTMTLTCVFDHRVVDGAQVAQFMCELRDLIESPETALLDL 393
>UniRef50_Q1AZ52 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Rubrobacter xylanophilus
DSM 9941|Rep: Catalytic domain of components of various
dehydrogenase complexes - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 396
Score = 67.3 bits (157), Expect = 3e-10
Identities = 29/83 (34%), Positives = 53/83 (63%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R L + ++ +++E+ + G+L+ ED GG T++N G++G TP++ P
Sbjct: 276 PVVRWAQALELGELAARLREVLERARSGRLSAEDTAGGTITLSNLGMYGIEGGTPLVTHP 335
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
Q+A++ AI +RP AV+G+VE+
Sbjct: 336 QAAVVFAGAIVERPWAVSGRVEV 358
>UniRef50_A0LQU7 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Acidothermus
cellulolyticus 11B|Rep: Catalytic domain of components
of various dehydrogenase complexes - Acidothermus
cellulolyticus (strain ATCC 43068 / 11B)
Length = 546
Score = 67.3 bits (157), Expect = 3e-10
Identities = 32/82 (39%), Positives = 47/82 (57%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
P ++D D L + D+ + I ELA +G+ + L G FTITN GVFG TPIINP
Sbjct: 422 PNIKDADRLSLIDLARAINELAATAREGRTPLAQLRNGTFTITNVGVFGVDTGTPIINPG 481
Query: 438 QSAILGMHAIKDRPMAVNGQVE 503
++AIL + ++ P + V+
Sbjct: 482 EAAILALGTVRRAPWLYHDAVQ 503
Score = 48.8 bits (111), Expect = 1e-04
Identities = 29/81 (35%), Positives = 48/81 (59%), Gaps = 2/81 (2%)
Frame = +1
Query: 19 LTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID--GD 192
+T F +++ P M+ + E GI+L ++ KAV+ AL+RYP VN+ D D
Sbjct: 341 VTEFVTIDVTPSMETLDRLRNRPEFA-GIKLSPLTLTAKAVLLALRRYPLVNSYWDDASD 399
Query: 193 DVVYHNYFDVSMAVSTPRGLV 255
++V +Y ++ +A +TPRGLV
Sbjct: 400 EIVVRHYVNLGIATATPRGLV 420
Score = 34.7 bits (76), Expect = 2.2
Identities = 17/34 (50%), Positives = 20/34 (58%)
Frame = +2
Query: 521 LALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
L LS+DHR+IDG FL + LEDP LL
Sbjct: 510 LGLSFDHRIIDGDLGSRFLRDVAAFLEDPGAALL 543
>UniRef50_A4AGT3 Cluster: Putative dihydrolipoamide acyltransferase
component; n=1; marine actinobacterium PHSC20C1|Rep:
Putative dihydrolipoamide acyltransferase component -
marine actinobacterium PHSC20C1
Length = 480
Score = 66.9 bits (156), Expect = 4e-10
Identities = 34/83 (40%), Positives = 48/83 (57%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
P L+D D + +A++ + I LA K T L GG +ITN GVFG TPI+NP
Sbjct: 357 PNLKDADMMTLAELTEAIGTLARNARASKATPASLNGGTISITNVGVFGIDAGTPILNPG 416
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
++AIL M A++ P NG+V +
Sbjct: 417 EAAILAMGAVRKMPWEHNGEVAL 439
Score = 39.5 bits (88), Expect = 0.076
Identities = 16/36 (44%), Positives = 24/36 (66%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLL 619
+M L+LS+DHRL+DG + FL + +L DP +L
Sbjct: 442 VMTLSLSFDHRLVDGEQGARFLTDVGAILNDPGTVL 477
Score = 34.3 bits (75), Expect = 2.9
Identities = 18/57 (31%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
Frame = +1
Query: 91 KRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGD--DVVYHNYFDVSMAVSTPRGLV 255
K G ++ KA+ + R P VN+ D + ++V Y ++ +AV+TPRGL+
Sbjct: 299 KAGGTAASVLAVLAKALCIGVARNPSVNSRWDAEANEIVEFGYVNLGIAVATPRGLM 355
>UniRef50_Q1EGH5 Cluster: Pyruvate dehydrogenase E2 subunit; n=3;
Nyctotherus ovalis|Rep: Pyruvate dehydrogenase E2
subunit - Nyctotherus ovalis
Length = 485
Score = 66.9 bits (156), Expect = 4e-10
Identities = 31/74 (41%), Positives = 43/74 (58%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP++ + G I K KEL K DG L E GG FTI+N G++G PI+NP
Sbjct: 356 TPIVPRANLKGFEQIAKITKELIAKAKDGTLKPEQFIGGTFTISNAGMYGISQLIPIVNP 415
Query: 435 PQSAILGMHAIKDR 476
PQ+ ILG+ A++ +
Sbjct: 416 PQACILGVSAVEKK 429
Score = 33.1 bits (72), Expect = 6.6
Identities = 22/74 (29%), Positives = 34/74 (45%)
Frame = +1
Query: 34 EVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNY 213
E + ++ LR Q K ++ +KA A + P N+S GD V +
Sbjct: 286 ECEVDKLLTLRSQ----LNKIASTKISINDMLIKACSLACLKVPVTNSSWMGDFVRRYKD 341
Query: 214 FDVSMAVSTPRGLV 255
D+S+AV TP GL+
Sbjct: 342 VDMSVAVQTPNGLI 355
>UniRef50_Q8F4N2 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex E2; n=3;
Leptospira|Rep: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex E2 -
Leptospira interrogans
Length = 458
Score = 66.5 bits (155), Expect = 6e-10
Identities = 30/84 (35%), Positives = 53/84 (63%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP +R+ D +++I ++IKELA + + KL + T G FT++N G+FG T +IN
Sbjct: 335 TPYIRNADQKSVSEIGREIKELASRARERKLKPAEYTDGTFTVSNLGMFGISSFTAVINE 394
Query: 435 PQSAILGMHAIKDRPMAVNGQVEI 506
P++AIL + A+ ++P+ G + +
Sbjct: 395 PEAAILAVGALVEKPVLKEGSIVV 418
Score = 44.4 bits (100), Expect = 0.003
Identities = 22/74 (29%), Positives = 37/74 (50%)
Frame = +1
Query: 34 EVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNY 213
E++ P+ LR Y + + ++ +KA +LK PEVN+S D ++ H
Sbjct: 261 ELDATPLDTLRNSYNKDLKLEGSSKISLNDLIIKACSLSLKEVPEVNSSWREDHILEHGR 320
Query: 214 FDVSMAVSTPRGLV 255
D+ +AVS GL+
Sbjct: 321 IDIGVAVSIEGGLI 334
>UniRef50_Q14PD7 Cluster: Putative dihydrolipoyllysine-residue
acetyltransferase component e2 of pyruvate dehydrogenase
protein; n=1; Spiroplasma citri|Rep: Putative
dihydrolipoyllysine-residue acetyltransferase component
e2 of pyruvate dehydrogenase protein - Spiroplasma citri
Length = 427
Score = 66.5 bits (155), Expect = 6e-10
Identities = 36/84 (42%), Positives = 51/84 (60%), Gaps = 1/84 (1%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV++ VD L + I K I +LA K + KL +++ G FTITN G G +TP+IN P
Sbjct: 305 PVVKGVDQLNIMQIAKMINDLATKTRERKLKPDEMKDGTFTITNFGSAGIEFATPVINFP 364
Query: 438 QSAILGMHAIKDRPMA-VNGQVEI 506
+ AILG+ IK P+ N ++EI
Sbjct: 365 EVAILGVGIIKKAPVINKNNEIEI 388
Score = 40.3 bits (90), Expect = 0.044
Identities = 19/34 (55%), Positives = 23/34 (67%)
Frame = +2
Query: 521 LALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
L+L+ DHRLIDG + FL + ELLE P LLL
Sbjct: 394 LSLTIDHRLIDGADGGRFLARVTELLESPALLLL 427
>UniRef50_A7HBV2 Cluster: Dehydrogenase complex catalytic domain;
n=2; Anaeromyxobacter|Rep: Dehydrogenase complex
catalytic domain - Anaeromyxobacter sp. Fw109-5
Length = 454
Score = 66.5 bits (155), Expect = 6e-10
Identities = 36/107 (33%), Positives = 57/107 (53%), Gaps = 3/107 (2%)
Frame = +3
Query: 195 RGLPQLFRRQHGGFYAARPG---TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLT 365
RG L RR G +A PV+R D + ++ ++I+ LA G+ ED+
Sbjct: 306 RGELVLHRRYDVGIASATDAGLVVPVVRGADRRSLVELAREIERLAQDAKAGRARPEDMG 365
Query: 366 GGNFTITNGGVFGSLMSTPIINPPQSAILGMHAIKDRPMAVNGQVEI 506
FTIT+ G G + +TP++N P+ ILG+H I+ P+ +GQV +
Sbjct: 366 RSTFTITSLGALGGMFATPVLNYPEVGILGVHRIRPTPVVRDGQVVV 412
Score = 35.9 bits (79), Expect = 0.94
Identities = 13/37 (35%), Positives = 24/37 (64%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
+M+++++ DHR++DG E+ F + LEDP L +
Sbjct: 415 VMHVSVTSDHRVVDGHEAAAFCYEVIRTLEDPNLLFM 451
>UniRef50_A1ZHD0 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=2; Bacteroidetes|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Microscilla marina ATCC 23134
Length = 454
Score = 66.5 bits (155), Expect = 6e-10
Identities = 28/77 (36%), Positives = 51/77 (66%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+++ D + + + K++ +LA + + KL ++L+GG +T++N G FG+ M TPI+ P
Sbjct: 328 PVIKNADQMNLLGLAKRVNDLANRARNNKLNPDELSGGTYTMSNIGGFGNEMGTPILVQP 387
Query: 438 QSAILGMHAIKDRPMAV 488
Q IL + AIK +P+ +
Sbjct: 388 QVGILAIGAIKKKPVVI 404
Score = 55.6 bits (128), Expect = 1e-06
Identities = 23/83 (27%), Positives = 50/83 (60%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
K + +TTF E ++ I+ R + + F+++HG ++ F +++A+ + L +P VN+S
Sbjct: 241 KRISPHVTTFVEADVTNIVMWRNKVKKEFQQKHGEKITFTPIFIEAIAKTLGDFPLVNSS 300
Query: 181 IDGDDVVYHNYFDVSMAVSTPRG 249
I+G++++ ++ MA + P G
Sbjct: 301 IEGENIIVKKDINIGMATALPSG 323
Score = 32.7 bits (71), Expect = 8.8
Identities = 12/30 (40%), Positives = 21/30 (70%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLE 601
MM+++ +YDHR++DG GF+ + + LE
Sbjct: 417 MMFMSHAYDHRIVDGALGGGFVRRVADYLE 446
>UniRef50_A4RXN8 Cluster: Predicted protein; n=3; cellular
organisms|Rep: Predicted protein - Ostreococcus
lucimarinus CCE9901
Length = 421
Score = 66.5 bits (155), Expect = 6e-10
Identities = 42/117 (35%), Positives = 60/117 (51%), Gaps = 3/117 (2%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
P++R LG+ I ++K LA + G LT +D+TGG FTI+N G+FG I+NPP
Sbjct: 299 PIVRSACCLGLKSISAEVKSLAGRARSGSLTPQDMTGGTFTISNLGMFGVKNFAAIVNPP 358
Query: 438 QSAILGMHAIKDRPM--AVNGQVEIL-R*CTWRCPTITV*SMVANPWASW*RSKSCW 599
Q+AIL + + + A G E+L T C V V A W +S C+
Sbjct: 359 QAAILAVGGARKEVVKNAEGGYEEVLVMSATLSCDHRVVDGAVG---AQWLQSFKCY 412
Score = 45.2 bits (102), Expect = 0.002
Identities = 32/87 (36%), Positives = 45/87 (51%), Gaps = 5/87 (5%)
Frame = +1
Query: 40 NMKPIMD-LRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYF 216
NM I + L KQ + + G ++ F VKA +AL P+VNAS GD + +
Sbjct: 226 NMMGIRETLNKQLADD-KAAEGAKISVNDFIVKASAKALLAVPDVNASWLGDKIRKYKKA 284
Query: 217 DVSMAVSTPRGL----VRRFCVMSIPS 285
D+S+AV T RGL VR C + + S
Sbjct: 285 DISVAVQTERGLMVPIVRSACCLGLKS 311
Score = 33.5 bits (73), Expect = 5.0
Identities = 16/37 (43%), Positives = 22/37 (59%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
+M LS DHR++DG +L + K LEDP +LL
Sbjct: 385 VMSATLSCDHRVVDGAVGAQWLQSFKCYLEDPMTMLL 421
>UniRef50_Q8ZUR6 Cluster: Pyruvate dehydrogenase E2; n=1;
Pyrobaculum aerophilum|Rep: Pyruvate dehydrogenase E2 -
Pyrobaculum aerophilum
Length = 383
Score = 66.5 bits (155), Expect = 6e-10
Identities = 31/82 (37%), Positives = 51/82 (62%)
Frame = +3
Query: 261 VLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPPQ 440
V+++ D G+ ++ K+I ELA K +GKL ++D+ G FTI+N G G L I+N P+
Sbjct: 263 VVKNADKKGLLEMAKEINELAQKAREGKLELQDVRGSTFTISNIGAVGGLGGLSILNYPE 322
Query: 441 SAILGMHAIKDRPMAVNGQVEI 506
+ IL + + +P AV ++EI
Sbjct: 323 AGILAVGQARKKPWAVGDRIEI 344
Score = 44.8 bits (101), Expect = 0.002
Identities = 27/76 (35%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Frame = +1
Query: 34 EVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDD--VVYH 207
EV+ ++ LR++ EKR GIRL + F KAV AL+ YP +N+ D + +V
Sbjct: 186 EVDFTELIKLRERVKAEAEKR-GIRLTLLPFIAKAVAMALREYPMLNSEYDEEKNAIVVK 244
Query: 208 NYFDVSMAVSTPRGLV 255
++ + V T +GLV
Sbjct: 245 KEVNLGIGVDTEQGLV 260
Score = 40.3 bits (90), Expect = 0.044
Identities = 18/34 (52%), Positives = 25/34 (73%)
Frame = +2
Query: 521 LALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
LA+S+DHR++DG F+ +KELLE+P LLL
Sbjct: 350 LAVSFDHRVVDGAYVARFMNRVKELLENPWLLLL 383
>UniRef50_Q820A3 Cluster: AceF; dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex (E2)
protein; n=1; Nitrosomonas europaea|Rep: AceF;
dihydrolipoamide acetyltransferase component of pyruvate
dehydrogenase complex (E2) protein - Nitrosomonas
europaea
Length = 453
Score = 66.1 bits (154), Expect = 8e-10
Identities = 38/97 (39%), Positives = 53/97 (54%), Gaps = 3/97 (3%)
Frame = +3
Query: 216 RRQHGGFYAARPG---TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTIT 386
R H GF A P PV+RD D G+ I +++ L+ +GKL D+ G +FTI+
Sbjct: 315 RYYHLGFAADTPNGLVVPVIRDADQKGVIGIAEELTRLSSLAREGKLKPGDMQGASFTIS 374
Query: 387 NGGVFGSLMSTPIINPPQSAILGMHAIKDRPMAVNGQ 497
+ G G TPIIN P+ AILG+ +P+ NGQ
Sbjct: 375 SLGGIGGTGFTPIINAPEVAILGVSRASLKPVYQNGQ 411
Score = 58.4 bits (135), Expect = 2e-07
Identities = 29/83 (34%), Positives = 48/83 (57%), Gaps = 4/83 (4%)
Frame = +1
Query: 19 LTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDG--- 189
+T F+E ++ + LRK + E + +G +L ++F +KAV ALK++PE NAS+D
Sbjct: 249 VTQFDEADVTDLEALRKNHNET-RQNNGTKLTILAFLIKAVTAALKKFPEFNASLDNSTT 307
Query: 190 -DDVVYHNYFDVSMAVSTPRGLV 255
++ Y+ + A TP GLV
Sbjct: 308 ESQLIIKRYYHLGFAADTPNGLV 330
>UniRef50_Q08V09 Cluster: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase; n=2;
Cystobacterineae|Rep: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase - Stigmatella
aurantiaca DW4/3-1
Length = 533
Score = 66.1 bits (154), Expect = 8e-10
Identities = 28/84 (33%), Positives = 52/84 (61%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP+++D D G+ I + +ELA + L ++ TGG+ T++N G++G +INP
Sbjct: 411 TPIIKDADQKGLQAISTEARELAERARKKALKPDEYTGGSITVSNLGMYGIDQFVAVINP 470
Query: 435 PQSAILGMHAIKDRPMAVNGQVEI 506
PQ+AI+ + A+ D+ + +GQ+ +
Sbjct: 471 PQAAIIAVGAVADKAVVRDGQITV 494
Score = 38.3 bits (85), Expect = 0.18
Identities = 23/74 (31%), Positives = 40/74 (54%)
Frame = +1
Query: 34 EVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNY 213
+V M M +R++ +A E + + VKAV AL+R P++N S+ G+ ++
Sbjct: 342 DVEMDAAMKIREE-AKALESKVSVN----DIVVKAVAVALRRSPKMNVSLQGNTILQFAT 396
Query: 214 FDVSMAVSTPRGLV 255
DV +AV+ GL+
Sbjct: 397 ADVGIAVAIEDGLI 410
Score = 36.3 bits (80), Expect = 0.71
Identities = 17/36 (47%), Positives = 23/36 (63%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLL 619
++ + LS DHR+IDG +L +K LLE P RLL
Sbjct: 497 ILTVTLSGDHRVIDGATGAEYLRELKNLLEHPMRLL 532
>UniRef50_Q8CX89 Cluster: Pyruvate dehydrogenase E2; n=4;
Bacillaceae|Rep: Pyruvate dehydrogenase E2 -
Oceanobacillus iheyensis
Length = 420
Score = 65.7 bits (153), Expect = 1e-09
Identities = 32/84 (38%), Positives = 52/84 (61%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV++ D + I +++KEL K + L+++++TG FTI+N G GS+ +TPIIN P
Sbjct: 295 PVIQSADIKSIRTIHREMKELMKKAKENTLSLKEMTGSTFTISNVGPMGSIGATPIINYP 354
Query: 438 QSAILGMHAIKDRPMAVNGQVEIL 509
+ A++ H K P+ VN EI+
Sbjct: 355 EVALMAFHKTKKAPV-VNDNDEIV 377
Score = 37.9 bits (84), Expect = 0.23
Identities = 15/39 (38%), Positives = 26/39 (66%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
MM + L++DHR+ DG ++ F K L+E+P LL+++
Sbjct: 381 MMNVTLTFDHRVTDGGNAIAFTNKFKALIENPRLLLIEL 419
Score = 32.7 bits (71), Expect = 8.8
Identities = 20/76 (26%), Positives = 38/76 (50%), Gaps = 2/76 (2%)
Frame = +1
Query: 34 EVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASI--DGDDVVYH 207
EV+M +++ RK E + + +F++KA+ ALK YP NA + + +++
Sbjct: 224 EVDMTELLEFRK------EIKSDADISVAAFFIKALTIALKEYPIFNAKLHEEKEEIRLE 277
Query: 208 NYFDVSMAVSTPRGLV 255
+ +A T GL+
Sbjct: 278 KGIHMGIATDTEEGLI 293
>UniRef50_Q48TW1 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex; n=41;
Streptococcus|Rep: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex -
Streptococcus pyogenes serotype M28
Length = 469
Score = 65.7 bits (153), Expect = 1e-09
Identities = 35/94 (37%), Positives = 52/94 (55%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+ D + ++D K++ K GKL +++G F+ITN G+FG+ PIIN P
Sbjct: 348 PVIHGADKMSLSDFVLASKDVIKKAQTGKLKAAEMSGSTFSITNLGMFGTKTFNPIINQP 407
Query: 438 QSAILGMHAIKDRPMAVNGQVEILR*CTWRCPTI 539
SAILG+ A P V+G++ + R C TI
Sbjct: 408 NSAILGVGATIPTPTVVDGEI-VARPIMAMCLTI 440
Score = 43.6 bits (98), Expect = 0.005
Identities = 17/38 (44%), Positives = 27/38 (71%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
P+M + L+ DHRL+DG F+V +K+L+E+P LL+
Sbjct: 432 PIMAMCLTIDHRLVDGMNGAKFMVDLKKLMENPFELLI 469
Score = 37.5 bits (83), Expect = 0.31
Identities = 24/87 (27%), Positives = 47/87 (54%), Gaps = 5/87 (5%)
Frame = +1
Query: 10 TAMLTTFN-EVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKR--YPEVNAS 180
TA T N +++M ++ LRK+ + + G+++ F AVV+ L + + +NAS
Sbjct: 260 TAPTFTLNYDIDMTEMIALRKKLIDPIMAKTGLKVSFTDLIGMAVVKTLMKPEHEYMNAS 319
Query: 181 I--DGDDVVYHNYFDVSMAVSTPRGLV 255
+ D +D+ H + ++ +AV GL+
Sbjct: 320 LINDANDIELHRFVNLGIAVGLDDGLI 346
>UniRef50_Q1YS54 Cluster: Dihydrolipoamide acetyltransferase; n=1;
gamma proteobacterium HTCC2207|Rep: Dihydrolipoamide
acetyltransferase - gamma proteobacterium HTCC2207
Length = 496
Score = 65.7 bits (153), Expect = 1e-09
Identities = 30/84 (35%), Positives = 51/84 (60%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP++ D + G+ +I ++LA + G+L E+ GG+F I+N G++G IINP
Sbjct: 374 TPIVSDANHKGLVEISNTTRDLATRAKLGRLKPEEFQGGSFCISNLGMYGIKQFDAIINP 433
Query: 435 PQSAILGMHAIKDRPMAVNGQVEI 506
PQ AIL + A + RP+ +G++ +
Sbjct: 434 PQGAILAVGAGEQRPVVKDGELAV 457
Score = 37.9 bits (84), Expect = 0.23
Identities = 17/44 (38%), Positives = 26/44 (59%)
Frame = +1
Query: 124 FYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLV 255
F VKA AL + P +N DG+ + Y + D+S+AV+ GL+
Sbjct: 330 FIVKACASALIKVPALNVQFDGEQLSYFSNADISVAVAIDDGLI 373
Score = 35.5 bits (78), Expect = 1.2
Identities = 16/36 (44%), Positives = 22/36 (61%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLL 619
+M L LS DHR+IDG + F+ +K LE P +L
Sbjct: 460 VMSLTLSSDHRIIDGAVAAQFMSVLKGYLEQPATML 495
>UniRef50_Q1IMV8 Cluster: Dihydrolipoamide acetyltransferase; n=1;
Acidobacteria bacterium Ellin345|Rep: Dihydrolipoamide
acetyltransferase - Acidobacteria bacterium (strain
Ellin345)
Length = 615
Score = 65.7 bits (153), Expect = 1e-09
Identities = 34/82 (41%), Positives = 48/82 (58%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PVLR+VD + I ++ EL+ + + KL E++ GG FTITN G G TPI+N P
Sbjct: 492 PVLRNVDQKNVYQIAAEMNELSKRARERKLKPEEMEGGTFTITNLGGIGGTSFTPIVNLP 551
Query: 438 QSAILGMHAIKDRPMAVNGQVE 503
+ AILG+ + P+ VN E
Sbjct: 552 EVAILGLSRGRTEPVWVNDHFE 573
Score = 45.2 bits (102), Expect = 0.002
Identities = 23/81 (28%), Positives = 46/81 (56%), Gaps = 2/81 (2%)
Frame = +1
Query: 19 LTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGD-- 192
+T + ++ + LR+++ + E G +L + +K + A+K++P+ NASID D
Sbjct: 411 VTQHDRADITELEKLREKFAKQAEAAGG-KLTVTAIALKVIAAAMKKFPKFNASIDIDRE 469
Query: 193 DVVYHNYFDVSMAVSTPRGLV 255
+++Y Y + +AV T GL+
Sbjct: 470 EIIYKKYVHIGVAVDTEAGLL 490
Score = 41.1 bits (92), Expect = 0.025
Identities = 18/37 (48%), Positives = 26/37 (70%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
M+ L+LSYDHR+IDG ++ +L + + LE P LLL
Sbjct: 577 MLPLSLSYDHRIIDGADAARYLRWVADALEQPVLLLL 613
>UniRef50_Q088Y7 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=1; Shewanella frigidimarina NCIMB
400|Rep: Dihydrolipoyllysine-residue succinyltransferase
- Shewanella frigidimarina (strain NCIMB 400)
Length = 252
Score = 65.7 bits (153), Expect = 1e-09
Identities = 34/83 (40%), Positives = 51/83 (61%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+++VD L + ++ ++LA + GKLT D GG+FT+T+ G G TPIIN P
Sbjct: 132 PVIKNVDALTLEELAIASQQLAERTRAGKLTFADTEGGSFTVTSLGPMGGTSFTPIINMP 191
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
+ AILG+ + +A NGQ+ I
Sbjct: 192 EVAILGVSREITKVVAQNGQIVI 214
Score = 43.6 bits (98), Expect = 0.005
Identities = 20/53 (37%), Positives = 34/53 (64%), Gaps = 2/53 (3%)
Frame = +1
Query: 103 IRLGFMSFYVKAVVEALKRYPEVNASI--DGDDVVYHNYFDVSMAVSTPRGLV 255
I + F +KA +EALK +P NAS+ DG+ ++ +Y+++ +AV T GL+
Sbjct: 78 IHFTLLPFILKATIEALKLFPAFNASLSDDGETLMLKHYYNLGIAVDTSNGLL 130
Score = 37.9 bits (84), Expect = 0.23
Identities = 16/30 (53%), Positives = 23/30 (76%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELL 598
PM+ L+LSYDHR+IDG + F+V +K+ L
Sbjct: 216 PMLPLSLSYDHRVIDGAMATRFMVQLKQNL 245
>UniRef50_Q5UWH1 Cluster: Dihydrolipoamide S-acetyltransferase
component of pyruvate dehydrogenase complex E2; n=3;
Halobacteriaceae|Rep: Dihydrolipoamide
S-acetyltransferase component of pyruvate dehydrogenase
complex E2 - Haloarcula marismortui (Halobacterium
marismortui)
Length = 540
Score = 65.3 bits (152), Expect = 1e-09
Identities = 32/82 (39%), Positives = 46/82 (56%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+ +VD G+ ++ + E K + L+ E++ GG FTI+N G G TPIIN P
Sbjct: 414 PVVENVDAKGLLEVASETNEKTQKARERSLSPEEMRGGTFTISNIGGIGGEYGTPIINQP 473
Query: 438 QSAILGMHAIKDRPMAVNGQVE 503
+SAIL + IK +P V E
Sbjct: 474 ESAILALGEIKKKPRVVEADGE 495
Score = 47.6 bits (108), Expect = 3e-04
Identities = 27/87 (31%), Positives = 49/87 (56%), Gaps = 2/87 (2%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
K + +T +EV++ ++D R E + IRL +M F +KA AL+ P+VN S
Sbjct: 327 KYTAPHVTHQDEVDVTALVDARSTLRREAEAQD-IRLTYMPFVMKACAAALQENPQVNVS 385
Query: 181 ID--GDDVVYHNYFDVSMAVSTPRGLV 255
+D +++V Y+++ +A +T GL+
Sbjct: 386 LDEANEEIVEKQYYNIGVATATDDGLL 412
Score = 39.5 bits (88), Expect = 0.076
Identities = 16/38 (42%), Positives = 29/38 (76%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
+M L+LS+DHR++DG ++ F +I++ L++P LLL+
Sbjct: 503 IMTLSLSFDHRVLDGADAAQFTNSIQKYLQNPNLLLLE 540
>UniRef50_A4WK39 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Pyrobaculum|Rep: Catalytic
domain of components of various dehydrogenase complexes
- Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321)
Length = 408
Score = 65.3 bits (152), Expect = 1e-09
Identities = 39/105 (37%), Positives = 57/105 (54%), Gaps = 3/105 (2%)
Frame = +3
Query: 195 RGLPQLFRRQHGGFYA-ARPG--TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLT 365
RG + RR H GF G V+RD D + +I +++ LA + GK +V+++
Sbjct: 261 RGEIVVKRRIHLGFAVDTEQGLMVVVVRDADKKSVLEIARELNALAERARAGKASVDEVR 320
Query: 366 GGNFTITNGGVFGSLMSTPIINPPQSAILGMHAIKDRPMAVNGQV 500
G FTITN G G + PIIN P++AI+ + I+ P VNG V
Sbjct: 321 GSTFTITNIGAIGGVGGLPIINYPEAAIMALGKIRKIPRVVNGAV 365
Score = 36.3 bits (80), Expect = 0.71
Identities = 16/37 (43%), Positives = 24/37 (64%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
+M + + +DHR++DG F +KELLED +LLL
Sbjct: 370 VMNVVVGFDHRVVDGAYVARFTNRVKELLEDVGKLLL 406
>UniRef50_O31550 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of acetoin cleaving system;
n=13; Bacillus|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of acetoin cleaving system -
Bacillus subtilis
Length = 398
Score = 65.3 bits (152), Expect = 1e-09
Identities = 31/75 (41%), Positives = 46/75 (61%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R + L + ++ + I E A K +G+ E+L G F+ITN G FG TPI+NPP
Sbjct: 277 PVIRHAEKLSLIELAQSISENAKKAREGRAGSEELQGSTFSITNLGAFGVEHFTPILNPP 336
Query: 438 QSAILGMHAIKDRPM 482
++ ILG+ A D P+
Sbjct: 337 ETGILGIGASYDTPV 351
Score = 48.0 bits (109), Expect = 2e-04
Identities = 24/83 (28%), Positives = 45/83 (54%)
Frame = +1
Query: 7 STAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID 186
++A LT + ++ + L+KQ E+R+G +L F +A V AL+ +P +N+
Sbjct: 193 NSAQLTITMKADITKLATLQKQLSPTAEERYGTKLTITHFVSRAAVLALQAHPVLNSFYQ 252
Query: 187 GDDVVYHNYFDVSMAVSTPRGLV 255
+ ++ H + + MAV+ GLV
Sbjct: 253 NERIITHPHVHLGMAVALENGLV 275
Score = 36.3 bits (80), Expect = 0.71
Identities = 15/34 (44%), Positives = 22/34 (64%)
Frame = +2
Query: 521 LALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
L+L++DHR DG + FL +K LE+P L+L
Sbjct: 365 LSLTFDHRACDGAPAAAFLKAMKTYLEEPAALIL 398
>UniRef50_Q9PKE7 Cluster: Pyruvate dehydrogenase, E2 component,
dihydrolipoamide acetyltransferase, putative; n=2;
Chlamydiales|Rep: Pyruvate dehydrogenase, E2 component,
dihydrolipoamide acetyltransferase, putative - Chlamydia
muridarum
Length = 428
Score = 64.9 bits (151), Expect = 2e-09
Identities = 30/84 (35%), Positives = 52/84 (61%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP++R D + I +IK LA + L E+ GG+F I+N G+ G T I+NP
Sbjct: 305 TPIIRCADRKNVGTISAEIKGLAARARQFSLKEEEYKGGSFCISNLGMTGISDFTAILNP 364
Query: 435 PQSAILGMHAIKDRPMAVNGQVEI 506
PQ+AIL + +++++P+ +NG++ +
Sbjct: 365 PQAAILAVGSVEEQPVVLNGELAV 388
Score = 36.3 bits (80), Expect = 0.71
Identities = 17/35 (48%), Positives = 25/35 (71%)
Frame = +2
Query: 521 LALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
L LS DHR+IDG + F+ +++LLE P+ LLL+
Sbjct: 394 LTLSVDHRVIDGYPAAMFMKRLQKLLEAPSVLLLN 428
Score = 35.9 bits (79), Expect = 0.94
Identities = 17/53 (32%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
Frame = +1
Query: 103 IRLGFMSFYVKAVVEALKRYPEVNASIDGDD--VVYHNYFDVSMAVSTPRGLV 255
I+L V+A ALK +PE+N+ + D ++ + D+S+AV+ P G++
Sbjct: 252 IKLSINDCIVRACALALKEFPEINSGFNSVDNTIIRFSTIDISIAVAIPDGVI 304
>UniRef50_Q74AE1 Cluster: Dehydrogenase complex E2 component,
dihydrolipamide acetyltransferase; n=4; Geobacter|Rep:
Dehydrogenase complex E2 component, dihydrolipamide
acetyltransferase - Geobacter sulfurreducens
Length = 418
Score = 64.9 bits (151), Expect = 2e-09
Identities = 29/85 (34%), Positives = 53/85 (62%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV++ +L + +I + LA + G +T E+++GG F+++N G++G +I PP
Sbjct: 297 PVVKGCQSLALKEIALQTVRLAERARSGAITQEEISGGTFSVSNLGMYGIDEFAAVIMPP 356
Query: 438 QSAILGMHAIKDRPMAVNGQVEILR 512
Q+AIL + A+ DRP+ +GQ+ + R
Sbjct: 357 QAAILAVGAVADRPVVRDGQLAVAR 381
Score = 33.1 bits (72), Expect = 6.6
Identities = 14/36 (38%), Positives = 23/36 (63%)
Frame = +2
Query: 515 MYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
M LS DHR++DG + FL ++ +LE+P +L+
Sbjct: 383 MRATLSCDHRVVDGAYAAQFLGELRRVLENPVLMLV 418
>UniRef50_Q1GTH9 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=5; Alphaproteobacteria|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Sphingopyxis alaskensis (Sphingomonas
alaskensis)
Length = 441
Score = 64.9 bits (151), Expect = 2e-09
Identities = 30/75 (40%), Positives = 46/75 (61%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+RD + + +I LA GK+ VE+LTGG T+T+ G G + +TP+IN P
Sbjct: 319 PVIRDAQDKNVWQLASEITRLAEAARTGKVKVEELTGGTLTVTSLGPLGGIATTPVINRP 378
Query: 438 QSAILGMHAIKDRPM 482
+ AI+G + I +RP+
Sbjct: 379 EVAIIGPNKIVERPI 393
Score = 37.5 bits (83), Expect = 0.31
Identities = 14/38 (36%), Positives = 26/38 (68%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
+M L++S DHR++DG ++ ++ +K+L+E P L D
Sbjct: 404 LMNLSISCDHRVVDGWDAASYVQALKKLIETPVLLFAD 441
>UniRef50_A6C4P4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex dihydrolipoamide acyltransferase (E2) component
and related enzyme; n=1; Planctomyces maris DSM
8797|Rep: Pyruvate/2-oxoglutarate dehydrogenase complex
dihydrolipoamide acyltransferase (E2) component and
related enzyme - Planctomyces maris DSM 8797
Length = 449
Score = 64.9 bits (151), Expect = 2e-09
Identities = 31/67 (46%), Positives = 42/67 (62%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV++DVD + I ++ LA+K D +L + D+ GG FTITN G G TPI+N P
Sbjct: 326 PVVKDVDKKNIITIANEMNALAIKARDRRLEMNDMQGGTFTITNLGGLGGTSFTPIVNYP 385
Query: 438 QSAILGM 458
+ AILGM
Sbjct: 386 EVAILGM 392
Score = 45.2 bits (102), Expect = 0.002
Identities = 19/38 (50%), Positives = 28/38 (73%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
M+ L+LSYDHR+I+G ++ F+V + LL DP LL+D
Sbjct: 411 MLPLSLSYDHRVINGADAARFIVRLSSLLSDPFNLLVD 448
Score = 44.8 bits (101), Expect = 0.002
Identities = 21/54 (38%), Positives = 32/54 (59%), Gaps = 2/54 (3%)
Frame = +1
Query: 100 GIRLGFMSFYVKAVVEALKRYPEVNASIDG--DDVVYHNYFDVSMAVSTPRGLV 255
G ++ + +KA+ AL YP N+S D D++VY NY ++ +AV T GLV
Sbjct: 271 GPKVTMTALAMKAIAIALHEYPSFNSSFDSQTDEIVYKNYINIGVAVDTENGLV 324
>UniRef50_A3VK82 Cluster: Putative uncharacterized protein; n=1;
Rhodobacterales bacterium HTCC2654|Rep: Putative
uncharacterized protein - Rhodobacterales bacterium
HTCC2654
Length = 472
Score = 64.9 bits (151), Expect = 2e-09
Identities = 35/82 (42%), Positives = 49/82 (59%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TPV+R+V G+ DI K LA K D L+ +++TGG FT++N G+FG IINP
Sbjct: 350 TPVVRNVGGRGLRDIAADAKALAGKARDRALSGDEMTGGTFTLSNLGMFGVREFDAIINP 409
Query: 435 PQSAILGMHAIKDRPMAVNGQV 500
PQ+AIL + + V+G V
Sbjct: 410 PQAAILAVGGPRREAREVDGGV 431
Score = 35.9 bits (79), Expect = 0.94
Identities = 22/85 (25%), Positives = 40/85 (47%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
K + T ++ + +MDLRK + ++ ++ F +KA AL ++P VN
Sbjct: 266 KQTVPHFYTTVDIEVDALMDLRKGMNGSADEGDP-KVSVNDFLLKACALALAKHPGVNVH 324
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
+ V D++MAV+ GL+
Sbjct: 325 VSDTGVTPFEQADIAMAVAIDGGLI 349
Score = 35.9 bits (79), Expect = 0.94
Identities = 22/56 (39%), Positives = 30/56 (53%)
Frame = +2
Query: 452 GYARYQRSSDGGEWSG*DPPMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLL 619
G R R DGG +M + LS DHR +DG + FL T++ L+E P RL+
Sbjct: 419 GPRREAREVDGGVGF---VSVMSVTLSADHRAVDGALAAEFLRTLRGLIEAPLRLV 471
>UniRef50_A0M206 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=1; Gramella forsetii KT0803|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Gramella forsetii
(strain KT0803)
Length = 507
Score = 64.9 bits (151), Expect = 2e-09
Identities = 33/75 (44%), Positives = 47/75 (62%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R+ D + +I +I ELA K + KL+ E++ GGNFTI+N G G TPI+ P
Sbjct: 383 PVVRNADQKTIIEISTEITELAEKARNVKLSAEEMKGGNFTISNLGGIGGTNFTPIVYHP 442
Query: 438 QSAILGMHAIKDRPM 482
Q AILG+ K +P+
Sbjct: 443 QVAILGVSRAKKQPV 457
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/34 (61%), Positives = 23/34 (67%)
Frame = +2
Query: 521 LALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
L+LSYDHR+IDG E V FL I LEDP LL
Sbjct: 472 LSLSYDHRIIDGAEGVRFLHWISRALEDPYEALL 505
>UniRef50_Q5L233 Cluster: Pyruvate dehydrogenase E2; n=2;
Geobacillus|Rep: Pyruvate dehydrogenase E2 - Geobacillus
kaustophilus
Length = 436
Score = 64.5 bits (150), Expect = 2e-09
Identities = 30/83 (36%), Positives = 49/83 (59%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+RD D + I K+I+EL K G + +++GG T++N G TPII+ P
Sbjct: 314 PVIRDADQKSLFQIAKEIEELTAKARAGTIQAVEMSGGTCTVSNIGSANGSWFTPIIHYP 373
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
QS +LG+ ++ +P+ V+ +EI
Sbjct: 374 QSCLLGIGKVEKKPVVVDDSIEI 396
Score = 54.8 bits (126), Expect = 2e-06
Identities = 25/81 (30%), Positives = 50/81 (61%), Gaps = 2/81 (2%)
Frame = +1
Query: 19 LTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID--GD 192
+T F E + ++ R++ + ++ G++L ++++ VKA+ LK+YP +NAS+D +
Sbjct: 233 VTHFGEADATRLVQHRRRI-QPLAEQQGVKLTYLAYVVKALAAVLKKYPMLNASLDEERE 291
Query: 193 DVVYHNYFDVSMAVSTPRGLV 255
++V H + + AV T RGL+
Sbjct: 292 EIVIHEFIHIGFAVDTDRGLL 312
>UniRef50_A4CQ51 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex;
n=13; Bacteroidetes|Rep: Lipoamide acyltransferase
component of branched-chain alpha-keto acid
dehydrogenase complex - Robiginitalea biformata HTCC2501
Length = 476
Score = 64.5 bits (150), Expect = 2e-09
Identities = 28/77 (36%), Positives = 46/77 (59%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R+ D L + + + + +LA + + L +++ G +T+TN G FGS+ TPIIN P
Sbjct: 350 PVIRNADQLNLVGMARAVNDLATRARNNALKPDEVRDGTYTVTNVGSFGSVFGTPIINQP 409
Query: 438 QSAILGMHAIKDRPMAV 488
Q IL + AI+ P +
Sbjct: 410 QVGILALGAIRKVPAVI 426
Score = 62.1 bits (144), Expect = 1e-08
Identities = 29/82 (35%), Positives = 52/82 (63%)
Frame = +1
Query: 4 NSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASI 183
+++A + +F EV++ I++ R + FEKR G +L F +++AV +ALK++P +N S+
Sbjct: 264 STSAHVQSFVEVDVTRIVEWRDRVKADFEKREGEKLTFTPIFMEAVAKALKKFPMMNISV 323
Query: 184 DGDDVVYHNYFDVSMAVSTPRG 249
DGD V+ ++ MA + P G
Sbjct: 324 DGDRVIKKKQINLGMAAALPDG 345
>UniRef50_A1SQB9 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=3; Actinomycetales|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Nocardioides sp. (strain BAA-499 / JS614)
Length = 474
Score = 64.5 bits (150), Expect = 2e-09
Identities = 33/89 (37%), Positives = 51/89 (57%), Gaps = 3/89 (3%)
Frame = +3
Query: 231 GFYAARPG---TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVF 401
G AA P P ++D +++ + ++ + I + +GK +++GG FTITN GVF
Sbjct: 336 GIAAATPRGLVVPNVKDAESMTLLELAQAINAVTATAREGKTQPAEMSGGTFTITNVGVF 395
Query: 402 GSLMSTPIINPPQSAILGMHAIKDRPMAV 488
G TPIINP +SAIL A++ +P V
Sbjct: 396 GVDSGTPIINPGESAILAFGAVRKQPWVV 424
Score = 41.9 bits (94), Expect = 0.014
Identities = 26/81 (32%), Positives = 47/81 (58%), Gaps = 2/81 (2%)
Frame = +1
Query: 19 LTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID--GD 192
+T + V++ M+L ++ E R +R+ + +AV+ A++R PE+N+ D
Sbjct: 267 VTEWVTVDVTATMELVERLKTRREFRE-VRVSPLLVLARAVMLAMRRTPEINSWWDDAAH 325
Query: 193 DVVYHNYFDVSMAVSTPRGLV 255
+VVY Y ++ +A +TPRGLV
Sbjct: 326 EVVYKRYVNLGIAAATPRGLV 346
Score = 37.5 bits (83), Expect = 0.31
Identities = 16/34 (47%), Positives = 22/34 (64%)
Frame = +2
Query: 521 LALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
LAL++DHR IDG + FL + E++ DP LL
Sbjct: 440 LALAFDHRHIDGEKGSRFLADVAEIMADPATALL 473
>UniRef50_A1R9E2 Cluster: Pyruvate dehydrogenase E2; n=2;
Actinomycetales|Rep: Pyruvate dehydrogenase E2 -
Arthrobacter aurescens (strain TC1)
Length = 493
Score = 64.5 bits (150), Expect = 2e-09
Identities = 32/83 (38%), Positives = 48/83 (57%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
P +R+ L +++ +I+ L DGK T +L G FT+ N GVFG S IIN P
Sbjct: 370 PSVRNAHELSARELDAEIRRLTAVARDGKATPTELGSGTFTLNNYGVFGVDGSAAIINYP 429
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
+ A+LG+ I D+P VNG++ +
Sbjct: 430 EVAMLGVGRIIDKPWVVNGELAV 452
Score = 35.1 bits (77), Expect = 1.6
Identities = 14/36 (38%), Positives = 23/36 (63%)
Frame = +2
Query: 521 LALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
L L++DHR+ DG + GFL + + +E+P L D+
Sbjct: 458 LTLAFDHRVCDGETAAGFLRYVADAIENPGGALADM 493
>UniRef50_Q19749 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=6; Bilateria|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex, mitochondrial
precursor - Caenorhabditis elegans
Length = 507
Score = 64.5 bits (150), Expect = 2e-09
Identities = 32/75 (42%), Positives = 46/75 (61%), Gaps = 1/75 (1%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMS-TPIIN 431
TP++ + G+A I +I ELA + +GKL + GG FT++N G+FGS+ T IIN
Sbjct: 383 TPIIFNAHAKGLATIASEIVELAQRAREGKLQPHEFQGGTFTVSNLGMFGSVSDFTAIIN 442
Query: 432 PPQSAILGMHAIKDR 476
PPQS IL + D+
Sbjct: 443 PPQSCILAIGGASDK 457
Score = 37.9 bits (84), Expect = 0.23
Identities = 21/78 (26%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
Frame = +1
Query: 31 NEVNMKPIMDLRKQYGEAFEKR---HGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVV 201
+E+ + ++ +R++ K ++ F +KA A +R PE N+ +
Sbjct: 305 SEIQLDTLLQVREKLNGLLAKGTSGQATKISINDFIIKASALACQRVPEANSYWMDSFIR 364
Query: 202 YHNYFDVSMAVSTPRGLV 255
+++ DVS+AVSTP GL+
Sbjct: 365 ENHHVDVSVAVSTPAGLI 382
>UniRef50_UPI00015A4520 Cluster: UPI00015A4520 related cluster; n=3;
Danio rerio|Rep: UPI00015A4520 UniRef100 entry - Danio
rerio
Length = 494
Score = 63.7 bits (148), Expect = 4e-09
Identities = 29/68 (42%), Positives = 43/68 (63%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP++RD G+ +I K LA K DGKL E+ GG+F+++N G+FG + +INP
Sbjct: 369 TPIIRDAADKGLQEISSTAKALAQKARDGKLLPEEYQGGSFSVSNLGMFGISEFSAVINP 428
Query: 435 PQSAILGM 458
PQ+ IL +
Sbjct: 429 PQACILAV 436
Score = 37.1 bits (82), Expect = 0.41
Identities = 18/51 (35%), Positives = 27/51 (52%)
Frame = +1
Query: 103 IRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLV 255
I++ F +KA +L+ P VN S D + +SMAV+T RGL+
Sbjct: 318 IKVSVNDFIIKAAAVSLRELPAVNVSWSADGPQPLGFIHISMAVATDRGLI 368
>UniRef50_A5V4B2 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Sphingomonas wittichii
RW1|Rep: Catalytic domain of components of various
dehydrogenase complexes - Sphingomonas wittichii RW1
Length = 420
Score = 63.7 bits (148), Expect = 4e-09
Identities = 34/74 (45%), Positives = 45/74 (60%), Gaps = 1/74 (1%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTP-IINP 434
PV+ L + I K++ E+ + KLT D+ GG FTI+N GV GSL +TP IIN
Sbjct: 297 PVVSKCQELSLLGIAKRLTEMVERARANKLTPADMRGGTFTISNHGVSGSLFATPIIINQ 356
Query: 435 PQSAILGMHAIKDR 476
PQSAILG+ + R
Sbjct: 357 PQSAILGIGKTEKR 370
>UniRef50_A3UGB6 Cluster: Dihydrolipoamide acetyltransferase; n=2;
Alphaproteobacteria|Rep: Dihydrolipoamide
acetyltransferase - Oceanicaulis alexandrii HTCC2633
Length = 437
Score = 63.7 bits (148), Expect = 4e-09
Identities = 30/88 (34%), Positives = 53/88 (60%), Gaps = 3/88 (3%)
Frame = +3
Query: 225 HGGFYAARPG---TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGG 395
H G AA P PV++ ++L + ++ ++K L GK T ++LTG TIT+ G
Sbjct: 300 HCGIAAATPNGLMVPVIKHAESLDIWEVAAEVKRLGDAAKAGKATKDELTGSTITITSLG 359
Query: 396 VFGSLMSTPIINPPQSAILGMHAIKDRP 479
G +++TP+IN P++AI+G++ ++ P
Sbjct: 360 AIGGIVTTPVINHPETAIIGVNKMQTLP 387
Score = 35.9 bits (79), Expect = 0.94
Identities = 15/38 (39%), Positives = 25/38 (65%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
+M L+ S+DHR++DG E+ + +K LE+P L +D
Sbjct: 400 IMNLSSSFDHRIVDGYEAALLVQEMKGYLENPATLFMD 437
>UniRef50_Q6KCM0 Cluster: Dihydrolipoyl transacetylase; n=1; Euglena
gracilis|Rep: Dihydrolipoyl transacetylase - Euglena
gracilis
Length = 434
Score = 63.7 bits (148), Expect = 4e-09
Identities = 32/73 (43%), Positives = 44/73 (60%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TPV+ + D G+ +I I+ LA +GKLT E GG FTI+N G +G T IINP
Sbjct: 323 TPVVYNADLKGLKEISNDIRTLAALAREGKLTPEQYIGGTFTISNLGSYGVKHFTAIINP 382
Query: 435 PQSAILGMHAIKD 473
PQ+ IL + A ++
Sbjct: 383 PQACILAVGAAQE 395
Score = 38.3 bits (85), Expect = 0.18
Identities = 18/44 (40%), Positives = 26/44 (59%)
Frame = +1
Query: 124 FYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLV 255
F VKA A K+ P N+ GD + + D+S+AV+TP GL+
Sbjct: 279 FLVKACALACKKVPAANSQWHGDKIRRFHSVDISVAVATPTGLI 322
Score = 32.7 bits (71), Expect = 8.8
Identities = 15/37 (40%), Positives = 22/37 (59%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
+M + LS DHR++DG +L K +E P+ LLL
Sbjct: 398 LMSVTLSCDHRVVDGAVGATWLQAFKGYVETPSSLLL 434
>UniRef50_A4S3G1 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 288
Score = 63.7 bits (148), Expect = 4e-09
Identities = 32/81 (39%), Positives = 48/81 (59%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP++ D + +I +K LA K +G L + GG+F+++N G+FG + I+NP
Sbjct: 180 TPIVTRADEKTLTEIGADVKGLAKKAREGALKPHEFMGGSFSVSNLGMFGVDAFSAILNP 239
Query: 435 PQSAILGMHAIKDRPMAVNGQ 497
PQ AIL + A KDR + V GQ
Sbjct: 240 PQGAILAIGAGKDRVVLVEGQ 260
>UniRef50_O00330 Cluster: Pyruvate dehydrogenase protein X
component, mitochondrial precursor; n=26; Amniota|Rep:
Pyruvate dehydrogenase protein X component,
mitochondrial precursor - Homo sapiens (Human)
Length = 501
Score = 63.7 bits (148), Expect = 4e-09
Identities = 29/68 (42%), Positives = 44/68 (64%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP+++D G+ +I +K L+ K DGKL E+ GG+F+I+N G+FG T +INP
Sbjct: 375 TPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINP 434
Query: 435 PQSAILGM 458
PQ+ IL +
Sbjct: 435 PQACILAV 442
Score = 41.9 bits (94), Expect = 0.014
Identities = 19/51 (37%), Positives = 31/51 (60%)
Frame = +1
Query: 103 IRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLV 255
I++ F +KA LK+ P+VN S DG+ + D+S+AV+T +GL+
Sbjct: 324 IKVSVNDFIIKAAAVTLKQMPDVNVSWDGEGPKQLPFIDISVAVATDKGLL 374
>UniRef50_Q9I1M0 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex (EC
2.3.1.168) (Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase); n=22; Proteobacteria|Rep:
Lipoamide acyltransferase component of branched-chain
alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
(Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase) - Pseudomonas aeruginosa
Length = 428
Score = 63.7 bits (148), Expect = 4e-09
Identities = 29/83 (34%), Positives = 50/83 (60%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PVLR ++ + ++ LA GK ++L+G T+++ GV G ++STP+IN P
Sbjct: 306 PVLRHAESRDLWGNASEVARLAEAARSGKAQRQELSGSTITLSSLGVLGGIVSTPVINHP 365
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
+ AI+G++ I +RPM V G + +
Sbjct: 366 EVAIVGVNRIVERPMVVGGNIVV 388
Score = 41.1 bits (92), Expect = 0.025
Identities = 16/38 (42%), Positives = 26/38 (68%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
MM L+ S+DHR++DG ++ F+ ++ LLE P L L+
Sbjct: 391 MMNLSSSFDHRVVDGMDAAAFIQAVRGLLEHPATLFLE 428
>UniRef50_O84249 Cluster: Dihydrolipoamide Acetyltransferase; n=7;
Chlamydiaceae|Rep: Dihydrolipoamide Acetyltransferase -
Chlamydia trachomatis
Length = 429
Score = 63.3 bits (147), Expect = 5e-09
Identities = 29/83 (34%), Positives = 51/83 (61%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
P++R D + I +IK LA K L E+ GG+F ++N G+ G T I+NPP
Sbjct: 307 PIVRCADRKNIGMISAEIKGLATKAKQQSLAEEEYKGGSFCVSNLGMTGISDFTAILNPP 366
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
Q+AIL + +++++P+ +NG++ +
Sbjct: 367 QAAILAVGSVEEQPVVLNGELAV 389
Score = 36.3 bits (80), Expect = 0.71
Identities = 17/57 (29%), Positives = 32/57 (56%), Gaps = 2/57 (3%)
Frame = +1
Query: 91 KRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDD--VVYHNYFDVSMAVSTPRGLV 255
+ I+L V+A ALK +PE+N+ + D ++ + D+S+AV+ P G++
Sbjct: 249 QEQNIKLSINDCIVRACALALKEFPEINSGFNSVDNKIIRFSTIDISIAVAIPDGVI 305
Score = 35.9 bits (79), Expect = 0.94
Identities = 17/35 (48%), Positives = 24/35 (68%)
Frame = +2
Query: 521 LALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
L LS DHR+IDG + F+ ++ LLE P+ LLL+
Sbjct: 395 LTLSVDHRVIDGYPAAMFMKRLQRLLEAPSVLLLN 429
>UniRef50_Q5DAR0 Cluster: SJCHGC04873 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC04873 protein - Schistosoma
japonicum (Blood fluke)
Length = 304
Score = 63.3 bits (147), Expect = 5e-09
Identities = 30/68 (44%), Positives = 44/68 (64%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP+L+ DTL ++DI K ++L K DG + + GG+FTI+N G++G T I+NP
Sbjct: 141 TPILKSADTLTVSDISKLSRQLIRKARDGIIQPPEFQGGSFTISNLGMYGIREFTAIVNP 200
Query: 435 PQSAILGM 458
PQ AIL +
Sbjct: 201 PQVAILAV 208
Score = 37.1 bits (82), Expect = 0.41
Identities = 19/54 (35%), Positives = 29/54 (53%), Gaps = 2/54 (3%)
Frame = +1
Query: 100 GIRLGFMSFYVKAVVEALKRYPEVNASIDG--DDVVYHNYFDVSMAVSTPRGLV 255
G+ F +KA AL+ +P+ N+ D + VY D+SMAV+T GL+
Sbjct: 87 GMNFSINDFIIKACALALRLFPDFNSIYDAQAESPVYLRSVDISMAVATSSGLI 140
>UniRef50_UPI0000ECB9E1 Cluster: Apoptosis inhibitor 5 (API-5).;
n=3; Amniota|Rep: Apoptosis inhibitor 5 (API-5). -
Gallus gallus
Length = 458
Score = 62.9 bits (146), Expect = 7e-09
Identities = 30/68 (44%), Positives = 43/68 (63%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP+++DV G+ +I K LA K DGKL E+ GG+F+I+N G+FG +INP
Sbjct: 330 TPIIKDVPAKGIQEIAASAKALAKKARDGKLLPEEYQGGSFSISNLGMFGINDFIAVINP 389
Query: 435 PQSAILGM 458
PQ+ IL +
Sbjct: 390 PQACILAV 397
>UniRef50_Q8RBW8 Cluster: Dihydrolipoamide acyltransferases; n=1;
Thermoanaerobacter tengcongensis|Rep: Dihydrolipoamide
acyltransferases - Thermoanaerobacter tengcongensis
Length = 399
Score = 62.9 bits (146), Expect = 7e-09
Identities = 34/95 (35%), Positives = 52/95 (54%), Gaps = 3/95 (3%)
Frame = +3
Query: 225 HGGFYAARPG---TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGG 395
H GF AR PV+++ L + ++ + + L G + E+L GG FT+TN G
Sbjct: 263 HLGFAVARGDELLVPVIKNAHRLNLNEMAVERRRLTDAVLQGIIKPEELQGGTFTVTNLG 322
Query: 396 VFGSLMSTPIINPPQSAILGMHAIKDRPMAVNGQV 500
+G TP++ P QSAILG+ I +RP+ NG +
Sbjct: 323 TYGVDFFTPVLYPKQSAILGIGRIVERPVLENGNI 357
Score = 33.1 bits (72), Expect = 6.6
Identities = 23/76 (30%), Positives = 36/76 (47%)
Frame = +1
Query: 10 TAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDG 189
TA T EV++ ++ +R + K+ G KAVV+A+ P + A IDG
Sbjct: 199 TAQYTLGREVDISALIKVRMEL-----KQKGSPANITDLIHKAVVQAILENPVMQAVIDG 253
Query: 190 DDVVYHNYFDVSMAVS 237
DD+V + AV+
Sbjct: 254 DDMVVPAEVHLGFAVA 269
>UniRef50_Q9KG97 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillus
halodurans|Rep: Pyruvate dehydrogenase E2 - Bacillus
halodurans
Length = 414
Score = 62.5 bits (145), Expect = 9e-09
Identities = 28/73 (38%), Positives = 46/73 (63%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+++ D + ++ +I +L+ + G L V+ +TG FTI+N G G L +TPIIN P
Sbjct: 290 PVIQNADQKSLLELAGEITQLSTQARKGTLNVQQMTGSTFTISNVGPIGGLHATPIINYP 349
Query: 438 QSAILGMHAIKDR 476
+ AIL +H ++ R
Sbjct: 350 EVAILALHKMEPR 362
Score = 56.0 bits (129), Expect = 8e-07
Identities = 27/81 (33%), Positives = 51/81 (62%), Gaps = 2/81 (2%)
Frame = +1
Query: 19 LTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGD-- 192
+T +E+ M + +LR+Q + + ++ GI+L F+ F++KA+V ALK + NASID +
Sbjct: 209 VTHVDEIEMDALKELREQL-KHYSEQKGIKLTFLPFFIKAIVSALKEFEYFNASIDEETN 267
Query: 193 DVVYHNYFDVSMAVSTPRGLV 255
++V + + +A T +GL+
Sbjct: 268 EIVLKKDYHIGIATDTEKGLI 288
Score = 47.6 bits (108), Expect = 3e-04
Identities = 21/47 (44%), Positives = 32/47 (68%)
Frame = +2
Query: 488 EWSG*DPPMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
EW MM ++LS+DHRL+DG +V F +KEL+E+P LL+++
Sbjct: 367 EWESVIKLMMNMSLSFDHRLVDGATAVRFTNRMKELIENPNLLLMEL 413
>UniRef50_Q8EJN8 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=103;
Proteobacteria|Rep: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Shewanella oneidensis
Length = 677
Score = 62.5 bits (145), Expect = 9e-09
Identities = 28/74 (37%), Positives = 47/74 (63%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+RDVD G+ ++ +++ +++++ DGKL D+ G FTI++ G G TPI+N P
Sbjct: 556 PVVRDVDKKGIIELSRELADISIRARDGKLKSADMQGSCFTISSLGGIGGTAFTPIVNYP 615
Query: 438 QSAILGMHAIKDRP 479
AILG+ + +P
Sbjct: 616 DVAILGVSKSEIKP 629
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/82 (32%), Positives = 50/82 (60%), Gaps = 3/82 (3%)
Frame = +1
Query: 19 LTTFNEVNMKPIMDLRKQYGEAFEKRHG-IRLGFMSFYVKAVVEALKRYPEVNASI--DG 189
+T F+E ++ + + RKQ +A K+ ++ + F +KAV + L+++P N+S+ DG
Sbjct: 473 VTQFDEADITEMEEFRKQQNDAAAKKKADYKITPLVFMMKAVAKTLQQFPVFNSSLSSDG 532
Query: 190 DDVVYHNYFDVSMAVSTPRGLV 255
+ ++ YF + +AV TP GLV
Sbjct: 533 ESLIQKKYFHIGVAVDTPNGLV 554
Score = 39.1 bits (87), Expect = 0.10
Identities = 21/48 (43%), Positives = 31/48 (64%), Gaps = 3/48 (6%)
Frame = +2
Query: 488 EWSG*D--PPMMY-LALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
+W+G + P +M L+LSYDHR+IDG + F VT+ +L D L+L
Sbjct: 630 KWNGKEFEPKLMLPLSLSYDHRVIDGAMAARFSVTLSGILSDIRTLIL 677
>UniRef50_Q0LND0 Cluster: Dihydrolipoamide S-succinyltransferase;
n=1; Herpetosiphon aurantiacus ATCC 23779|Rep:
Dihydrolipoamide S-succinyltransferase - Herpetosiphon
aurantiacus ATCC 23779
Length = 442
Score = 62.5 bits (145), Expect = 9e-09
Identities = 30/83 (36%), Positives = 51/83 (61%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R+ D+L + I +++++ + DGK ++DL GG FT++N G+F II PP
Sbjct: 321 PVVRNCDSLSLGAISNQMRDVIGRTRDGKAGLDDLQGGTFTVSNLGMFDVTNFIAIITPP 380
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
QSAIL + + P+ +G++ I
Sbjct: 381 QSAILAVGSTIATPVVRDGEIVI 403
Score = 42.7 bits (96), Expect = 0.008
Identities = 19/53 (35%), Positives = 32/53 (60%)
Frame = +1
Query: 97 HGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLV 255
HG +L +KA ALK++P +N++ GD ++ H +S+AV+T GL+
Sbjct: 267 HGGKLSVTELLLKACAIALKKFPALNSTFAGDKLLVHKDVHISVAVATDAGLL 319
Score = 37.5 bits (83), Expect = 0.31
Identities = 17/37 (45%), Positives = 24/37 (64%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
+M + +S DHR DG FLV +K LL++P +LLL
Sbjct: 406 LMNVTVSADHRATDGASVAQFLVELKNLLQNPFKLLL 442
>UniRef50_A4A156 Cluster: Pyruvate dehydrogenase, E2 component,
dihydrolipoamideacetyltransferase; n=2;
Planctomycetaceae|Rep: Pyruvate dehydrogenase, E2
component, dihydrolipoamideacetyltransferase -
Blastopirellula marina DSM 3645
Length = 472
Score = 62.5 bits (145), Expect = 9e-09
Identities = 30/81 (37%), Positives = 48/81 (59%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
P +R+ D L + +I + +++LA G +++ + GG FTI+N G G STPIIN P
Sbjct: 349 PNIRNADRLAIPEIARDVQKLAADVRGGTFSMDQIRGGTFTISNLGAIGGTYSTPIINVP 408
Query: 438 QSAILGMHAIKDRPMAVNGQV 500
+ AIL + + P+ VN Q+
Sbjct: 409 EVAILLVGRSRKLPVVVNDQI 429
Score = 56.0 bits (129), Expect = 8e-07
Identities = 32/81 (39%), Positives = 49/81 (60%), Gaps = 2/81 (2%)
Frame = +1
Query: 19 LTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID--GD 192
+T F++ ++ + LR+Q + + G++L MSF VKAV AL+ P +NA ID +
Sbjct: 268 VTNFDDADVTALEALRQQSKDDYASA-GVKLTSMSFLVKAVALALRNNPAINALIDMENN 326
Query: 193 DVVYHNYFDVSMAVSTPRGLV 255
VVY Y +V +AV + RGLV
Sbjct: 327 QVVYKEYVNVGIAVDSERGLV 347
Score = 47.6 bits (108), Expect = 3e-04
Identities = 23/37 (62%), Positives = 27/37 (72%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
MM L+LSYDHRL+DG + FL IK LE P+RLLL
Sbjct: 434 MMPLSLSYDHRLVDGATAARFLNEIKSYLEAPSRLLL 470
>UniRef50_A0YCP9 Cluster: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase; n=2; unclassified
Gammaproteobacteria|Rep: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase - marine gamma
proteobacterium HTCC2143
Length = 568
Score = 62.5 bits (145), Expect = 9e-09
Identities = 30/75 (40%), Positives = 47/75 (62%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+RDVD + ++ + E+A K D KL ++D+ GG FT+++ G G TPIIN P
Sbjct: 447 PVIRDVDKKSIWELAAETVEMAQKAKDRKLKIDDMQGGCFTVSSLGNIGGQGFTPIINVP 506
Query: 438 QSAILGMHAIKDRPM 482
+ AILG+ + +P+
Sbjct: 507 EVAILGVSKLSVKPL 521
Score = 52.8 bits (121), Expect = 8e-06
Identities = 27/81 (33%), Positives = 48/81 (59%), Gaps = 2/81 (2%)
Frame = +1
Query: 19 LTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASI--DGD 192
+T F++ N+ + + R+ +A +R G+++ + F +KA AL+ P+ NAS+ G
Sbjct: 366 VTQFDDANISDLEEFRQSL-KAEAERRGVKITPLPFLLKACAAALRENPKFNASLHTSGH 424
Query: 193 DVVYHNYFDVSMAVSTPRGLV 255
+VY Y ++ +AV TP GLV
Sbjct: 425 QLVYKQYVNIGIAVDTPLGLV 445
Score = 34.7 bits (76), Expect = 2.2
Identities = 17/37 (45%), Positives = 24/37 (64%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
M+ L+LSYDHR I+G ++ FL + +L D RL L
Sbjct: 532 MLPLSLSYDHRAINGGDAGRFLTYLTAILADIRRLAL 568
>UniRef50_Q4QJI5 Cluster: Dihydrolipoamide branched chain
transacylase, putative; n=2; Leishmania|Rep:
Dihydrolipoamide branched chain transacylase, putative -
Leishmania major
Length = 477
Score = 62.5 bits (145), Expect = 9e-09
Identities = 28/74 (37%), Positives = 47/74 (63%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV++ V+ + DI ++ L +G KLT +D+TGG FT++N GV G+ ++TP++ PP
Sbjct: 352 PVVKHVERKSILDIANDMQVLIERGKSNKLTTQDMTGGTFTLSNIGVIGATVTTPVLLPP 411
Query: 438 QSAILGMHAIKDRP 479
Q AI + ++ P
Sbjct: 412 QVAIGAIGRLQKLP 425
Score = 37.5 bits (83), Expect = 0.31
Identities = 16/39 (41%), Positives = 26/39 (66%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
++ ++ + DHR+IDG V F T K+LLE P +L+D+
Sbjct: 438 LICVSFTADHRVIDGASMVRFANTYKQLLEHPENMLVDL 476
>UniRef50_Q97CK2 Cluster: Pyruvate dehydrogenase E2 /
dihydrolipoamide acetyltransferase; n=3;
Thermoplasma|Rep: Pyruvate dehydrogenase E2 /
dihydrolipoamide acetyltransferase - Thermoplasma
volcanium
Length = 400
Score = 62.5 bits (145), Expect = 9e-09
Identities = 28/71 (39%), Positives = 45/71 (63%)
Frame = +3
Query: 261 VLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPPQ 440
V++D D M +I +I + A + + +L ++++ FTITN G G ++STPIIN P+
Sbjct: 286 VVKDADRKSMYEITAEITDKAERARNNQLKIDEVQDSTFTITNVGTIGGVLSTPIINYPE 345
Query: 441 SAILGMHAIKD 473
AILG+H + D
Sbjct: 346 VAILGVHRVMD 356
Score = 46.0 bits (104), Expect = 9e-04
Identities = 18/39 (46%), Positives = 30/39 (76%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
+MYL+LS DHRLIDG + F++ +K+++EDP L+ ++
Sbjct: 362 IMYLSLSCDHRLIDGAVATRFIMDLKKIIEDPNSLIYEM 400
>UniRef50_O66119 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=31; Bacteria|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex - Zymomonas mobilis
Length = 440
Score = 62.5 bits (145), Expect = 9e-09
Identities = 27/84 (32%), Positives = 51/84 (60%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP+L+ DT ++ + ++KEL + +G+L ++ GG +I+N G+FG +INP
Sbjct: 317 TPILKQADTKSLSALSVEMKELIARAREGRLQPQEYQGGTSSISNMGMFGIKQFNAVINP 376
Query: 435 PQSAILGMHAIKDRPMAVNGQVEI 506
PQ++IL + + + RP ++ + I
Sbjct: 377 PQASILAIGSGERRPWVIDDAITI 400
Score = 47.2 bits (107), Expect = 4e-04
Identities = 24/74 (32%), Positives = 41/74 (55%)
Frame = +1
Query: 34 EVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNY 213
+V M ++ LR + E+ ++ I++ +KA ALK P VN + DGD ++ +
Sbjct: 244 DVQMDALLKLRSELNESLAVQN-IKISVNDMLIKAQALALKATPNVNVAFDGDQMLQFSQ 302
Query: 214 FDVSMAVSTPRGLV 255
D+S+AVS GL+
Sbjct: 303 ADISVAVSVEGGLI 316
Score = 34.3 bits (75), Expect = 2.9
Identities = 13/30 (43%), Positives = 20/30 (66%)
Frame = +2
Query: 530 SYDHRLIDGRESVGFLVTIKELLEDPTRLL 619
S+DHR+IDG ++ F+ K L+E P +L
Sbjct: 409 SFDHRVIDGADAAAFMSAFKHLVEKPLGIL 438
>UniRef50_P35489 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=4; Acholeplasmataceae|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Acholeplasma
laidlawii
Length = 544
Score = 62.5 bits (145), Expect = 9e-09
Identities = 29/83 (34%), Positives = 49/83 (59%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
P +++ D L + ++ +++ LA K++++ TGG FTITN G G TP+IN P
Sbjct: 422 PNIKNADRLSVFELASQVRSLADDTIARKISMDQQTGGTFTITNFGSAGIAFGTPVINYP 481
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
+ AILG+ I +P V +++I
Sbjct: 482 ELAILGIGKIDRKPWVVGNEIKI 504
Score = 55.2 bits (127), Expect = 1e-06
Identities = 28/77 (36%), Positives = 47/77 (61%), Gaps = 2/77 (2%)
Frame = +1
Query: 31 NEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASI--DGDDVVY 204
+E+N+ +++ R + + + GI+L +M+F KAV+ ALK +P NAS D D+V
Sbjct: 345 DEINVDALVNFRNE-AKGLAESKGIKLTYMAFIAKAVLIALKEFPMFNASFNHDTDEVYI 403
Query: 205 HNYFDVSMAVSTPRGLV 255
+ ++ MAV TP GL+
Sbjct: 404 KKFINLGMAVDTPDGLI 420
Score = 42.3 bits (95), Expect = 0.011
Identities = 19/34 (55%), Positives = 26/34 (76%)
Frame = +2
Query: 521 LALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
L+L+ DHR+IDG + FL+ +KELL +PT LLL
Sbjct: 510 LSLAVDHRIIDGADGGRFLMRVKELLTNPTLLLL 543
>UniRef50_Q2J8A0 Cluster: Dehydrogenase subunit; n=9; Actinobacteria
(class)|Rep: Dehydrogenase subunit - Frankia sp. (strain
CcI3)
Length = 487
Score = 62.1 bits (144), Expect = 1e-08
Identities = 29/78 (37%), Positives = 46/78 (58%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+ + L + + +KI +LA + +++ ++L GG FT+TN G G+L TPIIN P
Sbjct: 358 PVIHNAGDLNLIGLARKIDDLASRTRANRISPDELGGGTFTLTNTGSRGALFDTPIINQP 417
Query: 438 QSAILGMHAIKDRPMAVN 491
Q ILG + +P V+
Sbjct: 418 QVGILGTGIVTKKPAVVD 435
Score = 61.3 bits (142), Expect = 2e-08
Identities = 32/84 (38%), Positives = 49/84 (58%), Gaps = 2/84 (2%)
Frame = +1
Query: 10 TAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID- 186
+A LTT E ++ I LR + F+ R GI+L F+ F+ A AL+ +P++N+SID
Sbjct: 273 SAQLTTVVEADVTRIARLRDRAKSGFQAREGIKLSFLPFFALATCAALREFPQLNSSIDV 332
Query: 187 -GDDVVYHNYFDVSMAVSTPRGLV 255
V YH ++ +AV + RGLV
Sbjct: 333 EAGTVTYHGEENLGIAVDSERGLV 356
Score = 36.7 bits (81), Expect = 0.54
Identities = 14/30 (46%), Positives = 22/30 (73%)
Frame = +2
Query: 515 MYLALSYDHRLIDGRESVGFLVTIKELLED 604
+YL+L+YDHR++DG ++ FL K LE+
Sbjct: 449 VYLSLTYDHRIVDGADAARFLAFTKHRLEN 478
>UniRef50_Q03Y73 Cluster: Acetoin/pyruvate dehydrogenase complex, E2
component, dihydrolipoamide succinyltransferase; n=2;
Lactobacillales|Rep: Acetoin/pyruvate dehydrogenase
complex, E2 component, dihydrolipoamide
succinyltransferase - Leuconostoc mesenteroides subsp.
mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 431
Score = 62.1 bits (144), Expect = 1e-08
Identities = 28/80 (35%), Positives = 51/80 (63%), Gaps = 2/80 (2%)
Frame = +1
Query: 19 LTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID--GD 192
+T F+ V+++ ++ RK + E GIRL ++++ VKA+ K++PE+NAS+D
Sbjct: 225 VTNFDSVDVRKLVGHRKAFKEMARDDKGIRLTYLAYAVKALAAVAKKFPELNASVDMKAQ 284
Query: 193 DVVYHNYFDVSMAVSTPRGL 252
++VYH+ ++ +AV P GL
Sbjct: 285 EIVYHDDVNMGIAVDAPTGL 304
Score = 50.8 bits (116), Expect = 3e-05
Identities = 30/83 (36%), Positives = 45/83 (54%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+++ D + I ++I +LA DG +T + GG TI+N G TPIIN
Sbjct: 307 PVIKNADRKSIFTIAQEITDLAEAVRDGSITPAQMQGGTITISNLGSARGTWFTPIINGK 366
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
+ AILG+ +I P+ VN E+
Sbjct: 367 EVAILGLGSILKEPI-VNDDGEL 388
Score = 41.1 bits (92), Expect = 0.025
Identities = 19/38 (50%), Positives = 26/38 (68%)
Frame = +2
Query: 515 MYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
M L+L+YDHRLIDG L +K+LL DP +L++V
Sbjct: 394 MKLSLTYDHRLIDGMLGQSALNYLKQLLSDPAYMLMEV 431
>UniRef50_A2TU26 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-ketoacid dehydrogenase complex;
n=4; Bacteroidetes|Rep: Lipoamide acyltransferase
component of branched-chain alpha-ketoacid dehydrogenase
complex - Dokdonia donghaensis MED134
Length = 439
Score = 62.1 bits (144), Expect = 1e-08
Identities = 29/73 (39%), Positives = 45/73 (61%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+++ + + +I ++ L+ + KL +D+ G FTI+N G FGS+M TPIIN P
Sbjct: 313 PVVKNANQRNLVEIAAEVNRLSSLARENKLGGDDVKGSTFTISNVGTFGSVMGTPIINQP 372
Query: 438 QSAILGMHAIKDR 476
++AIL IK R
Sbjct: 373 EAAILATGIIKKR 385
Score = 59.7 bits (138), Expect = 7e-08
Identities = 24/83 (28%), Positives = 50/83 (60%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
K+++ +T + E ++ ++ R AF+++HG RL F +V+AV +A++ +P +N S
Sbjct: 226 KHTSPHVTAYVEADLTEMVQWRNDNKVAFQEKHGERLTFTPLFVEAVAKAVEEFPMINVS 285
Query: 181 IDGDDVVYHNYFDVSMAVSTPRG 249
+DG +++ ++ MA + P G
Sbjct: 286 VDGKNIIVKEDINIGMATALPSG 308
Score = 37.5 bits (83), Expect = 0.31
Identities = 20/38 (52%), Positives = 25/38 (65%), Gaps = 2/38 (5%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLE--DPTRLL 619
MMYL+LS+DHR++DG FL I + LE D TR L
Sbjct: 402 MMYLSLSFDHRIVDGYLGGSFLRKIADHLEQFDTTRAL 439
>UniRef50_A0NRH8 Cluster: Branched-chain alpha-keto acid
dehydrogenase E2 subunit; n=1; Stappia aggregata IAM
12614|Rep: Branched-chain alpha-keto acid dehydrogenase
E2 subunit - Stappia aggregata IAM 12614
Length = 301
Score = 62.1 bits (144), Expect = 1e-08
Identities = 29/67 (43%), Positives = 43/67 (64%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+RDVD G+ I +I +LA + + K+ +++ G + TITN G G TPI+NPP
Sbjct: 180 PVIRDVDRKGLWQIAAEIADLASRALERKVRPDEMGGASMTITNLGGIGGTAFTPIVNPP 239
Query: 438 QSAILGM 458
+ AILG+
Sbjct: 240 EVAILGI 246
Score = 36.3 bits (80), Expect = 0.71
Identities = 16/37 (43%), Positives = 25/37 (67%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
M+ L LSYDHR+I+G ++ FL LL +P R+++
Sbjct: 265 MVPLDLSYDHRVINGADAARFLSYYAGLLREPRRMMM 301
>UniRef50_P20285 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=40; Eukaryota|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex, mitochondrial
precursor - Neurospora crassa
Length = 458
Score = 62.1 bits (144), Expect = 1e-08
Identities = 32/71 (45%), Positives = 47/71 (66%), Gaps = 1/71 (1%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMS-TPIIN 431
TP+++ V+ G+ I +KELA K DGKL E+ GG+ +I+N G+ ++ S T IIN
Sbjct: 330 TPIVKGVEGKGLESISAAVKELAKKARDGKLKPEEYQGGSISISNMGMNPAVQSFTAIIN 389
Query: 432 PPQSAILGMHA 464
PPQ+AIL + A
Sbjct: 390 PPQAAILAVGA 400
Score = 39.1 bits (87), Expect = 0.10
Identities = 23/73 (31%), Positives = 40/73 (54%)
Frame = +1
Query: 37 VNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYF 216
+++ ++ LR+ + + R+ +L F +KA+ A KR P VN+S +
Sbjct: 259 LSVSKLLKLRQALNSSADGRY--KLSVNDFLIKAMGIASKRVPTVNSSWRDGVIRQFETV 316
Query: 217 DVSMAVSTPRGLV 255
DVS+AV+TP GL+
Sbjct: 317 DVSVAVATPNGLI 329
>UniRef50_P36413 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=2; Dictyostelium
discoideum|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor - Dictyostelium
discoideum (Slime mold)
Length = 592
Score = 62.1 bits (144), Expect = 1e-08
Identities = 29/68 (42%), Positives = 41/68 (60%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP++R VD G+ I +K+LA K +GKL + G FTI+N G+ G +INP
Sbjct: 467 TPIVRGVDMKGLNSISTSVKQLAEKAQNGKLHPSEFESGTFTISNLGMLGIKQFAAVINP 526
Query: 435 PQSAILGM 458
PQ+AIL +
Sbjct: 527 PQAAILAL 534
Score = 35.1 bits (77), Expect = 1.6
Identities = 16/50 (32%), Positives = 31/50 (62%)
Frame = +1
Query: 103 IRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGL 252
+++ F VKA + AL+ P VN++ + ++ D+++AV+TP+GL
Sbjct: 416 VKISVNDFIVKASLPALRDNPVVNSTWTDQFIRRYHNIDINVAVNTPQGL 465
Score = 33.9 bits (74), Expect = 3.8
Identities = 14/37 (37%), Positives = 25/37 (67%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
++ + LS DHR+IDG +L + K+ +E+P +L+L
Sbjct: 556 ILSVTLSCDHRVIDGAVGAEWLKSFKDYVENPIKLIL 592
>UniRef50_Q2GCH9 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=1;
Neorickettsia sennetsu str. Miyayama|Rep: Pyruvate
dehydrogenase complex, E2 component, dihydrolipoamide
acetyltransferase - Neorickettsia sennetsu (strain
Miyayama)
Length = 403
Score = 61.7 bits (143), Expect = 2e-08
Identities = 29/75 (38%), Positives = 46/75 (61%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP++ D L ++ I +++EL K G+L + GG+FT++N G++G T IINP
Sbjct: 282 TPIVFSADKLSLSSISDEVRELVDKAKAGRLQPREFQGGSFTVSNLGMYGIDEFTAIINP 341
Query: 435 PQSAILGMHAIKDRP 479
PQ+AIL + A + P
Sbjct: 342 PQAAILAVGAARKVP 356
Score = 36.3 bits (80), Expect = 0.71
Identities = 18/71 (25%), Positives = 39/71 (54%)
Frame = +1
Query: 43 MKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDV 222
++ ++ +K++ + E + + F +KA AL + P +N S +G+ + + D+
Sbjct: 215 LQHLLSAKKKFYDCLETKVTVN----DFVIKACAFALDKNPAMNVSWEGEFIRQNQTIDI 270
Query: 223 SMAVSTPRGLV 255
S+AV+ P GL+
Sbjct: 271 SVAVAIPDGLI 281
Score = 35.5 bits (78), Expect = 1.2
Identities = 15/33 (45%), Positives = 23/33 (69%)
Frame = +2
Query: 521 LALSYDHRLIDGRESVGFLVTIKELLEDPTRLL 619
L LS DHR+IDG + F+ ++K+ +EDP +L
Sbjct: 371 LTLSCDHRVIDGALAARFMQSLKKAIEDPVIML 403
>UniRef50_A6TMP1 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Alkaliphilus
metalliredigens QYMF|Rep: Catalytic domain of components
of various dehydrogenase complexes - Alkaliphilus
metalliredigens QYMF
Length = 438
Score = 61.7 bits (143), Expect = 2e-08
Identities = 31/83 (37%), Positives = 47/83 (56%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV++DVD G+ + ++ L+ D L + L G FTITN G G PIIN P
Sbjct: 316 PVIKDVDQKGLMSLMEESVRLSQSAKDKSLKLNQLKGSTFTITNLGSLGVKSGMPIINYP 375
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
+ AI+G+ I+ +P+ V+ +V I
Sbjct: 376 EVAIIGIGQIEQKPVVVDNEVVI 398
Score = 52.8 bits (121), Expect = 8e-06
Identities = 24/76 (31%), Positives = 47/76 (61%), Gaps = 2/76 (2%)
Frame = +1
Query: 31 NEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDD--VVY 204
+EV++ ++ R++ F + I++ ++ F +KAV+ ALK YP NA +D ++ ++
Sbjct: 238 DEVDVTDLVAYREEMKNHFVEEKEIKITYLPFMIKAVMLALKDYPRFNAQLDEENQMLIL 297
Query: 205 HNYFDVSMAVSTPRGL 252
Y+++ +AV TP GL
Sbjct: 298 KKYYNIGIAVDTPEGL 313
Score = 34.7 bits (76), Expect = 2.2
Identities = 17/37 (45%), Positives = 25/37 (67%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
MM L+LS+DHR++DG + FL K+ ++D LLL
Sbjct: 401 MMPLSLSFDHRVLDGGDVGRFLNQFKKYIKDIKGLLL 437
>UniRef50_Q8RWN9 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component 2 of pyruvate dehydrogenase
complex, mitochondrial precursor; n=14; cellular
organisms|Rep: Dihydrolipoyllysine-residue
acetyltransferase component 2 of pyruvate dehydrogenase
complex, mitochondrial precursor - Arabidopsis thaliana
(Mouse-ear cress)
Length = 539
Score = 61.7 bits (143), Expect = 2e-08
Identities = 31/80 (38%), Positives = 48/80 (60%), Gaps = 1/80 (1%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITN-GGVFGSLMSTPIINP 434
PV++D D G++ I ++++ LA K + L ED GG FT++N GG FG +INP
Sbjct: 415 PVVKDADKKGLSTIGEEVRFLAQKAKENSLKPEDYEGGTFTVSNLGGPFGIKQFCAVINP 474
Query: 435 PQSAILGMHAIKDRPMAVNG 494
PQ+AIL + + + R + G
Sbjct: 475 PQAAILAIGSAEKRVVPGTG 494
>UniRef50_UPI0000DB7177 Cluster: PREDICTED: similar to Pyruvate
dehydrogenase protein X component, mitochondrial
precursor (Dihydrolipoamide dehydrogenase-binding
protein of pyruvate dehydrogenase complex)
(Lipoyl-containing pyruvate dehydrogenase complex
component X) (E3-binding protein) (E...; n=1; Apis
mellifera|Rep: PREDICTED: similar to Pyruvate
dehydrogenase protein X component, mitochondrial
precursor (Dihydrolipoamide dehydrogenase-binding
protein of pyruvate dehydrogenase complex)
(Lipoyl-containing pyruvate dehydrogenase complex
component X) (E3-binding protein) (E... - Apis mellifera
Length = 598
Score = 61.3 bits (142), Expect = 2e-08
Identities = 32/68 (47%), Positives = 41/68 (60%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP++ D + DI K IKELA K G+L E+ GG FTI+N G+FG IIN
Sbjct: 468 TPIVFDATAKSILDISKNIKELAEKAKTGQLKPEEFQGGTFTISNLGMFGIKHFRAIINL 527
Query: 435 PQSAILGM 458
PQ+AIL +
Sbjct: 528 PQTAILAV 535
Score = 36.3 bits (80), Expect = 0.71
Identities = 16/35 (45%), Positives = 23/35 (65%)
Frame = +2
Query: 515 MYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLL 619
M +LSYD R ID ++ FL +K +LEDP+ L+
Sbjct: 552 MSTSLSYDRRAIDEDQAADFLAVLKAMLEDPSFLI 586
Score = 35.9 bits (79), Expect = 0.94
Identities = 20/74 (27%), Positives = 34/74 (45%)
Frame = +1
Query: 34 EVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNY 213
++ + I ++RK+ K GI + F KA AL P +N D ++
Sbjct: 399 DIKIDKINEIRKEL-----KADGINISINDFITKATAHALVECPFINTLYKNDQIIQMPR 453
Query: 214 FDVSMAVSTPRGLV 255
D+S+AV+ GL+
Sbjct: 454 VDISIAVAIESGLI 467
>UniRef50_Q7WED2 Cluster: Probable 2-oxo acid dehydrogenases
acyltransferase; n=2; Bacteria|Rep: Probable 2-oxo acid
dehydrogenases acyltransferase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 416
Score = 61.3 bits (142), Expect = 2e-08
Identities = 31/72 (43%), Positives = 44/72 (61%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PVL +D + DI + L + GK T ED++GG +I+N G+F PIINPP
Sbjct: 287 PVLHGLDHASLDDIAAQSGALLGRVRAGKATREDMSGGAISISNAGMFNVTYMAPIINPP 346
Query: 438 QSAILGMHAIKD 473
QSAILG+ +I++
Sbjct: 347 QSAILGVGSIRE 358
Score = 37.5 bits (83), Expect = 0.31
Identities = 18/35 (51%), Positives = 24/35 (68%)
Frame = +2
Query: 515 MYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLL 619
M L L+ DHRL DG ++ FL + +LL+DP RLL
Sbjct: 374 MGLVLAADHRLHDGASALAFLNHVIDLLQDPYRLL 408
Score = 35.9 bits (79), Expect = 0.94
Identities = 20/50 (40%), Positives = 25/50 (50%)
Frame = +1
Query: 106 RLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLV 255
RL F + AV AL P N + D +V DV +AVST RGL+
Sbjct: 236 RLTLNHFVIAAVARALAAMPHQNRIWNDDHIVQFQGIDVGVAVSTERGLM 285
>UniRef50_Q5ZVD7 Cluster: Pyruvate dehydrogenase E2 component; n=5;
Legionellales|Rep: Pyruvate dehydrogenase E2 component -
Legionella pneumophila subsp. pneumophila (strain
Philadelphia 1 /ATCC 33152 / DSM 7513)
Length = 550
Score = 61.3 bits (142), Expect = 2e-08
Identities = 31/78 (39%), Positives = 48/78 (61%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+++VD L + DI K++ L+ K + LT D++GG FTI++ G G TPI+N P
Sbjct: 429 PVIKNVDKLSVIDIAKEMSRLSTKAREKGLTPIDMSGGCFTISSLGGIGGTAFTPIVNSP 488
Query: 438 QSAILGMHAIKDRPMAVN 491
+ AILG+ +P+ N
Sbjct: 489 EVAILGLSRSIIKPIYDN 506
Score = 57.6 bits (133), Expect = 3e-07
Identities = 28/81 (34%), Positives = 48/81 (59%), Gaps = 2/81 (2%)
Frame = +1
Query: 19 LTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID--GD 192
+T F+E ++ + RK E+ K +L ++F V +AL YP+ NAS+D G+
Sbjct: 348 VTQFDEADITDLEAFRKSESES-AKNQDYKLTLLAFVCSVVCKALHAYPQFNASLDTSGE 406
Query: 193 DVVYHNYFDVSMAVSTPRGLV 255
+++Y Y+++ +AV TP GLV
Sbjct: 407 NLIYKKYYNIGIAVDTPNGLV 427
Score = 35.9 bits (79), Expect = 0.94
Identities = 17/37 (45%), Positives = 25/37 (67%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
M+ ++LSYDHR+IDG E+ F + + L D R+LL
Sbjct: 514 MLPISLSYDHRVIDGAEAARFTRFLCDCLGDIRRVLL 550
>UniRef50_A0JZU9 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Micrococcineae|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Arthrobacter sp. (strain FB24)
Length = 518
Score = 61.3 bits (142), Expect = 2e-08
Identities = 30/83 (36%), Positives = 47/83 (56%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
P +R+ + +++ +I+ L +GK T +L G FT+ N GVFG S IIN P
Sbjct: 395 PSVRNAGKMSARELDAEIRRLTAVVREGKATPSELGSGTFTLNNYGVFGVDGSAAIINHP 454
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
+ ILG+ I D+P VNG++ +
Sbjct: 455 EVGILGVGRIIDKPWVVNGELAV 477
Score = 34.3 bits (75), Expect = 2.9
Identities = 14/36 (38%), Positives = 24/36 (66%)
Frame = +2
Query: 521 LALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
L L++DHR+ DG + GFL + + +E+P +L D+
Sbjct: 483 LTLTFDHRVCDGGTAGGFLRYVADAIENPGSVLADM 518
>UniRef50_Q6ABX9 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=5; Actinomycetales|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Leifsonia xyli
subsp. xyli
Length = 452
Score = 61.3 bits (142), Expect = 2e-08
Identities = 31/93 (33%), Positives = 50/93 (53%), Gaps = 3/93 (3%)
Frame = +3
Query: 231 GFYAARPG---TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVF 401
G AA P P +++ + + ++ ++EL + +GK D+ G TITN GVF
Sbjct: 319 GIAAATPRGLIVPNVKEAQGMSLLELAGALEELTLTAREGKTQPADMANGTITITNIGVF 378
Query: 402 GSLMSTPIINPPQSAILGMHAIKDRPMAVNGQV 500
G TPI+NP + I+ + IK +P V+G+V
Sbjct: 379 GMDTGTPILNPGEVGIVALGTIKQKPWVVDGEV 411
Score = 43.2 bits (97), Expect = 0.006
Identities = 16/52 (30%), Positives = 35/52 (67%)
Frame = +1
Query: 100 GIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLV 255
G+++ + KA+V A++R P VN++ ++++ +Y ++ +A +TPRGL+
Sbjct: 278 GVKVSPLLIMAKAIVWAVRRNPTVNSTWTDEEIIVRHYVNLGIAAATPRGLI 329
Score = 32.7 bits (71), Expect = 8.8
Identities = 14/32 (43%), Positives = 22/32 (68%)
Frame = +2
Query: 530 SYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
S+DHR++DG + FL + ++E+P LLLD
Sbjct: 422 SFDHRVVDGDVASRFLADVASIIEEPA-LLLD 452
>UniRef50_P09062 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex (EC
2.3.1.168) (Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase); n=27; Proteobacteria|Rep:
Lipoamide acyltransferase component of branched-chain
alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
(Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase) - Pseudomonas putida
Length = 423
Score = 61.3 bits (142), Expect = 2e-08
Identities = 27/83 (32%), Positives = 51/83 (61%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PVLR + + +I LA + K + E+L+G T+T+ G G ++STP++N P
Sbjct: 301 PVLRHAEAGSLWANAGEISRLANAARNNKASREELSGSTITLTSLGALGGIVSTPVVNTP 360
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
+ AI+G++ + +RP+ ++GQ+ +
Sbjct: 361 EVAIVGVNRMVERPVVIDGQIVV 383
Score = 37.9 bits (84), Expect = 0.23
Identities = 15/38 (39%), Positives = 26/38 (68%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
MM L+ S+DHR++DG ++ F+ ++ LLE P L ++
Sbjct: 386 MMNLSSSFDHRVVDGMDAALFIQAVRGLLEQPACLFVE 423
Score = 37.5 bits (83), Expect = 0.31
Identities = 23/87 (26%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
K A + E+++ + LR+Q G +L + F V+A+V AL+ +P++NA+
Sbjct: 214 KRRVAHFSYVEEIDVTALEALRQQLNSKHGDSRG-KLTLLPFLVRALVVALRDFPQINAT 272
Query: 181 IDGDD--VVYHNYFDVSMAVSTPRGLV 255
D + + H V +A GL+
Sbjct: 273 YDDEAQIITRHGAVHVGIATQGDNGLM 299
>UniRef50_Q68FJ5 Cluster: MGC86218 protein; n=3; Tetrapoda|Rep:
MGC86218 protein - Xenopus laevis (African clawed frog)
Length = 478
Score = 60.9 bits (141), Expect = 3e-08
Identities = 29/68 (42%), Positives = 43/68 (63%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP+++ + G+ +I K LA K DGKL E+ GG+F+I+N G+FG + +INP
Sbjct: 350 TPIIKQAASKGIQEIAATAKVLAQKARDGKLLPEEYQGGSFSISNLGMFGITGFSAVINP 409
Query: 435 PQSAILGM 458
PQS IL +
Sbjct: 410 PQSCILAV 417
Score = 45.6 bits (103), Expect = 0.001
Identities = 25/85 (29%), Positives = 43/85 (50%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
K+S + N+ ++ LRK+ + I++ F +KA ALK+ P VN +
Sbjct: 270 KSSIPHAYATTDCNLGAVLQLRKELA-----KDNIKVSVNDFIIKATAAALKQMPNVNVT 324
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
+G+ D+S+AV+T RGL+
Sbjct: 325 WNGEGATTLESIDISIAVATDRGLI 349
>UniRef50_Q9FC63 Cluster: Putative acyltransferase; n=1;
Streptomyces coelicolor|Rep: Putative acyltransferase -
Streptomyces coelicolor
Length = 417
Score = 60.9 bits (141), Expect = 3e-08
Identities = 33/86 (38%), Positives = 51/86 (59%), Gaps = 1/86 (1%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TPV++ L +A + + + +LA + G LT +D++G FTI+N G G+L T I+ P
Sbjct: 284 TPVVKAAGDLTVAGLARAVHDLADRARGGHLTPDDVSGATFTISNTGSRGALFDTVIVPP 343
Query: 435 PQSAILGMHAIKDRPMAVN-GQVEIL 509
Q+AILG+ A RP V G E++
Sbjct: 344 NQAAILGVGATVRRPGVVRVGDEEVI 369
Score = 57.6 bits (133), Expect = 3e-07
Identities = 31/83 (37%), Positives = 50/83 (60%), Gaps = 2/83 (2%)
Frame = +1
Query: 13 AMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGD 192
A LT+ E ++ +M LR + + F R G++L M F+VKA +ALK +P VNA I+ D
Sbjct: 201 AQLTSTVEADVTRLMRLRNRAKDGFLAREGLKLSPMPFFVKAAAQALKAHPVVNARINED 260
Query: 193 D--VVYHNYFDVSMAVSTPRGLV 255
+ + Y + ++ +AV T GL+
Sbjct: 261 EGTITYFDSENIGIAVDTEAGLM 283
Score = 40.3 bits (90), Expect = 0.044
Identities = 15/30 (50%), Positives = 24/30 (80%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLE 601
+++L+LSYDHRL+DG ++ +L +K LLE
Sbjct: 374 LVHLSLSYDHRLVDGADAARYLTAVKALLE 403
>UniRef50_A1ZE93 Cluster: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase; n=7; Bacteria|Rep:
Pyruvate dehydrogenase complex dihydrolipoamide
acetyltransferase - Microscilla marina ATCC 23134
Length = 547
Score = 60.9 bits (141), Expect = 3e-08
Identities = 33/84 (39%), Positives = 46/84 (54%), Gaps = 1/84 (1%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R D L + + K+L K D KL D G F+++N G+FG T IINPP
Sbjct: 425 PVVRFADNLTFSQVATTTKDLVSKAKDKKLQPADWEGSTFSVSNLGMFGVEDFTAIINPP 484
Query: 438 QSAILGMHAIKDRPMAVN-GQVEI 506
S IL + IK P+ + GQ+E+
Sbjct: 485 DSCILAVGGIKQTPVVNDEGQIEV 508
Score = 41.9 bits (94), Expect = 0.014
Identities = 23/73 (31%), Positives = 38/73 (52%)
Frame = +1
Query: 34 EVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNY 213
E+ M IM RKQ +++ F +KA A++++P++NA D + Y+N+
Sbjct: 354 EIRMDAIMKARKQINAVSP----VKVSFNDIIIKASALAIRKHPKINAYWLEDKIRYNNH 409
Query: 214 FDVSMAVSTPRGL 252
V MAV+ GL
Sbjct: 410 IHVGMAVAVKDGL 422
Score = 38.7 bits (86), Expect = 0.13
Identities = 15/37 (40%), Positives = 27/37 (72%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
+M + LS DHR++DG + FL T+K+++E+P +L+
Sbjct: 511 IMKVTLSSDHRVVDGALAASFLKTLKQMIENPYMMLV 547
>UniRef50_Q8D2N2 Cluster: AceF protein; n=1; Wigglesworthia
glossinidia endosymbiont of Glossina brevipalpis|Rep:
AceF protein - Wigglesworthia glossinidia brevipalpis
Length = 496
Score = 60.5 bits (140), Expect = 4e-08
Identities = 32/75 (42%), Positives = 45/75 (60%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+ DVD G+ +I ++ ++ K + KL D+TGG FTI+N G G TPIIN P
Sbjct: 375 PVIFDVDKKGIIEISHELFNISNKARNKKLISRDMTGGCFTISNLGGIGGREFTPIINYP 434
Query: 438 QSAILGMHAIKDRPM 482
+ AILG+ +PM
Sbjct: 435 EVAILGVSQASIQPM 449
Score = 50.8 bits (116), Expect = 3e-05
Identities = 26/81 (32%), Positives = 47/81 (58%), Gaps = 2/81 (2%)
Frame = +1
Query: 19 LTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASI--DGD 192
+T F +V++ + RK ++ +++ +SF +K+V ALK YP N+S+ D +
Sbjct: 295 VTQFEQVDISELESFRKNQNNTL--KYKVKITILSFIIKSVFFALKEYPLFNSSLSKDKN 352
Query: 193 DVVYHNYFDVSMAVSTPRGLV 255
++ YF++ +AVST GLV
Sbjct: 353 KLILKKYFNIGIAVSTDYGLV 373
Score = 40.3 bits (90), Expect = 0.044
Identities = 18/36 (50%), Positives = 27/36 (75%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLL 619
M+ L+LSYDHR+IDG E F++ +K+++ D RLL
Sbjct: 460 MLPLSLSYDHRVIDGSEGAKFIIFLKKIISD-IRLL 494
>UniRef50_Q9RPS3 Cluster: Dihydrolipoamide acyltransferase; n=3;
Lactobacillales|Rep: Dihydrolipoamide acyltransferase -
Enterococcus faecalis (Streptococcus faecalis)
Length = 432
Score = 60.5 bits (140), Expect = 4e-08
Identities = 25/73 (34%), Positives = 46/73 (63%)
Frame = +1
Query: 34 EVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNY 213
E ++ ++ LR + F+++ G+ L F F+ KAV++ALK+ P++N S D ++YH
Sbjct: 233 EADVTNLVQLRNSLKDEFKQQEGLSLSFFPFFAKAVIQALKKNPKINTSWDDGSIIYHKD 292
Query: 214 FDVSMAVSTPRGL 252
++S+AV+T L
Sbjct: 293 VNLSIAVTTDEHL 305
Score = 59.7 bits (138), Expect = 7e-08
Identities = 29/73 (39%), Positives = 43/73 (58%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV++ D +A + K+I LA + G L +++ GG FT+ N G GS+ S IIN P
Sbjct: 308 PVIQQADNYSIAGLAKEINRLAQEVRQGTLASKEMQGGTFTLNNTGTLGSVQSMGIINHP 367
Query: 438 QSAILGMHAIKDR 476
Q+AIL + +I R
Sbjct: 368 QAAILQVESINKR 380
>UniRef50_Q1VYW1 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvatedehydrogenase
complex; n=11; Bacteroidetes|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvatedehydrogenase complex - Psychroflexus torquis
ATCC 700755
Length = 572
Score = 60.5 bits (140), Expect = 4e-08
Identities = 30/83 (36%), Positives = 45/83 (54%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PVL D + I +K LA K + KL ++ G FT++N G+FG T IIN P
Sbjct: 451 PVLEFADQQSLTQIGSNVKNLAGKAKNKKLQPNEMEGSTFTVSNLGMFGITEFTSIINQP 510
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
SAIL + I ++P+ G++ +
Sbjct: 511 NSAILSVGTIVEKPVVKKGEIVV 533
Score = 41.9 bits (94), Expect = 0.014
Identities = 26/85 (30%), Positives = 43/85 (50%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
KNS EV+M+ M R E + +++ F +KA AL+++P+VN+S
Sbjct: 369 KNSAPHYYLNIEVDMENAMASRSHINEMPD----VKVSFNDLVIKASAMALRKHPQVNSS 424
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
DG+ N+ V +AV+ GL+
Sbjct: 425 WDGEVTKIANHIHVGVAVAVDEGLL 449
Score = 35.5 bits (78), Expect = 1.2
Identities = 16/35 (45%), Positives = 21/35 (60%)
Frame = +2
Query: 515 MYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLL 619
M L L+ DHR +DG FL T+K LE+P +L
Sbjct: 537 MILTLACDHRTVDGATGAKFLQTLKIYLENPVTML 571
>UniRef50_A6GG26 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvatedehydrogenase
complex; n=1; Plesiocystis pacifica SIR-1|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvatedehydrogenase complex - Plesiocystis pacifica
SIR-1
Length = 436
Score = 60.5 bits (140), Expect = 4e-08
Identities = 30/83 (36%), Positives = 47/83 (56%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R D + I ++ K L D L ED++GG FT++N G+FG +INP
Sbjct: 311 PVVRYADQKSLEAISRESKALGKSARDKHLRPEDMSGGTFTVSNLGMFGIESFAAVINPG 370
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
++ IL + AI+ RP+ G++ I
Sbjct: 371 EAGILAVGAIESRPVVQGGELVI 393
Score = 50.0 bits (114), Expect = 5e-05
Identities = 26/74 (35%), Positives = 40/74 (54%)
Frame = +1
Query: 34 EVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNY 213
+V+M+ R + EA + G ++ F VKAV +L+ +P VNAS DGD +
Sbjct: 238 DVDMEKAFAFRADFNEAVPE--GTKISFNDLIVKAVARSLRDFPSVNASFDGDKAIIRGD 295
Query: 214 FDVSMAVSTPRGLV 255
+V +AV+ GLV
Sbjct: 296 VNVGIAVAVEDGLV 309
Score = 32.7 bits (71), Expect = 8.8
Identities = 13/37 (35%), Positives = 23/37 (62%)
Frame = +2
Query: 515 MYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
M + +S DHR+ DG + +L ++ LE+P ++L D
Sbjct: 397 MKMTISADHRVTDGAVAAKWLTKVRGYLENPLKMLTD 433
>UniRef50_Q98FT5 Cluster: Dihydrolipoamide acetyltransferase
homoserine dehydrogenase; n=23; Alphaproteobacteria|Rep:
Dihydrolipoamide acetyltransferase homoserine
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 454
Score = 60.1 bits (139), Expect = 5e-08
Identities = 28/84 (33%), Positives = 49/84 (58%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP++R D ++ I ++K+LA + KL E+ GG ++N G+FG +INP
Sbjct: 332 TPIIRHADEKTLSTISNEMKDLASRARSRKLKPEEYQGGTTAVSNLGMFGIKDFAAVINP 391
Query: 435 PQSAILGMHAIKDRPMAVNGQVEI 506
P + IL + A ++R + NG+++I
Sbjct: 392 PHATILAVGAGEERAVVKNGEIKI 415
Score = 39.9 bits (89), Expect = 0.058
Identities = 20/50 (40%), Positives = 28/50 (56%)
Frame = +1
Query: 106 RLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLV 255
+L +KA+ ALK P+ NAS +V H + DV +AVS P GL+
Sbjct: 282 KLSVNDMVIKAMAMALKAVPDANASWTETAMVKHKHADVGVAVSIPGGLI 331
Score = 33.9 bits (74), Expect = 3.8
Identities = 15/37 (40%), Positives = 22/37 (59%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
+M + LS DHR +DG LV K L+E+P +L+
Sbjct: 418 VMSVTLSTDHRAVDGALGAELLVAFKRLIENPMGMLV 454
>UniRef50_Q4FS31 Cluster: Dihydrolipoyllysine acetyltransferase
component of pyruvate dehydrogenase complex; n=2;
Psychrobacter|Rep: Dihydrolipoyllysine acetyltransferase
component of pyruvate dehydrogenase complex -
Psychrobacter arcticum
Length = 578
Score = 60.1 bits (139), Expect = 5e-08
Identities = 28/66 (42%), Positives = 42/66 (63%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+++ G+ I +I ELA+K D KL+ +DL G +FTI++ G+ G TP++N P
Sbjct: 455 PVIKNAHEKGIKQIAIEIGELAIKARDKKLSTKDLQGASFTISSQGILGGTAFTPLVNWP 514
Query: 438 QSAILG 455
Q ILG
Sbjct: 515 QVGILG 520
Score = 39.9 bits (89), Expect = 0.058
Identities = 18/37 (48%), Positives = 26/37 (70%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
M+ L+LSYDHR+I+G ++ F + LL DP R+LL
Sbjct: 542 MLPLSLSYDHRVINGADAAVFTRYVATLLADPRRILL 578
>UniRef50_Q4L1A5 Cluster: Dihydrolipoamide acetyltransferase; n=2;
Mycoplasma synoviae|Rep: Dihydrolipoamide
acetyltransferase - Mycoplasma synoviae
Length = 309
Score = 60.1 bits (139), Expect = 5e-08
Identities = 27/79 (34%), Positives = 45/79 (56%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+++ + L + D+ +++ LA + + +D+ FT+TN G GSL P+IN P
Sbjct: 187 PVIKNANALSVLDLAREVSRLASAARNKTIKPDDMKNAGFTVTNYGSVGSLWGVPVINYP 246
Query: 438 QSAILGMHAIKDRPMAVNG 494
+ AILG+ AI+D G
Sbjct: 247 ELAILGVGAIQDEAFVEKG 265
Score = 39.9 bits (89), Expect = 0.058
Identities = 23/86 (26%), Positives = 42/86 (48%), Gaps = 2/86 (2%)
Frame = +1
Query: 4 NSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASI 183
++ A + VNM + DLR ++ K +++ F+ F +KAV ALK +P +A
Sbjct: 100 SNVAYTNLVHRVNMTKLWDLRSSIKDSLLKSEDVKITFLPFILKAVSVALKEFPLFSAKY 159
Query: 184 D--GDDVVYHNYFDVSMAVSTPRGLV 255
+ + + ++ AV T GL+
Sbjct: 160 NEAKSTLDFPGVINLGFAVDTEAGLM 185
Score = 35.1 bits (77), Expect = 1.6
Identities = 16/35 (45%), Positives = 22/35 (62%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRL 616
+MYL ++ DHR IDG + F +K+LLE P L
Sbjct: 272 VMYLTVAADHRWIDGADVGRFASRVKQLLESPELL 306
>UniRef50_A0JUQ7 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=9; Actinobacteria
(class)|Rep: Catalytic domain of components of various
dehydrogenase complexes - Arthrobacter sp. (strain FB24)
Length = 462
Score = 60.1 bits (139), Expect = 5e-08
Identities = 32/95 (33%), Positives = 50/95 (52%), Gaps = 3/95 (3%)
Frame = +3
Query: 231 GFYAARPG---TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVF 401
G AA P P ++D ++ + ++ + L GK + +LTGG +ITN GVF
Sbjct: 327 GIAAATPRGLTVPNIKDAHSMSLTELSTALTALTETARAGKTSPAELTGGTISITNIGVF 386
Query: 402 GSLMSTPIINPPQSAILGMHAIKDRPMAVNGQVEI 506
G TPI+NP ++AIL M A++ P +V +
Sbjct: 387 GIDAGTPILNPGEAAILAMGAVRKMPWEYRDEVAL 421
Score = 46.0 bits (104), Expect = 9e-04
Identities = 25/79 (31%), Positives = 46/79 (58%), Gaps = 2/79 (2%)
Frame = +1
Query: 22 TTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID--GDD 195
T F +++ P M+L + +A G +L ++ KA++ AL+R P +N+ D +
Sbjct: 259 TEFLTIDVTPTMELLSRL-KASRTFEGFKLTPLTLVAKALLIALRRQPSLNSRWDEANQE 317
Query: 196 VVYHNYFDVSMAVSTPRGL 252
+V +NY ++ +A +TPRGL
Sbjct: 318 IVQYNYVNLGIAAATPRGL 336
Score = 38.3 bits (85), Expect = 0.18
Identities = 17/36 (47%), Positives = 24/36 (66%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLL 619
+M L+LS+DHRL+DG + FL I +L DP +L
Sbjct: 424 VMTLSLSFDHRLVDGEQGSRFLADIGAVLADPGMVL 459
>UniRef50_P45118 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=11; Proteobacteria|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Haemophilus
influenzae
Length = 567
Score = 60.1 bits (139), Expect = 5e-08
Identities = 27/75 (36%), Positives = 47/75 (62%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV ++V+ G+ ++ +++ E++ K +GKLT D+ GG FTI++ G G+ PI+N P
Sbjct: 446 PVFKNVNKKGIIELSRELMEVSKKAREGKLTASDMQGGCFTISSLGGIGTTHFAPIVNAP 505
Query: 438 QSAILGMHAIKDRPM 482
+ AILG+ P+
Sbjct: 506 EVAILGVSKSSMEPV 520
Score = 50.8 bits (116), Expect = 3e-05
Identities = 27/82 (32%), Positives = 48/82 (58%), Gaps = 3/82 (3%)
Frame = +1
Query: 19 LTTFNEVNMKPIMDLRKQYGEAFEKRH-GIRLGFMSFYVKAVVEALKRYPEVNASI--DG 189
+T F++ ++ + RK+ EK+ G+++ + F +KAV +AL+ YP N+SI D
Sbjct: 363 VTHFDKADITDLEAFRKEQNALREKQKLGVKITPVVFIMKAVAKALEAYPRFNSSITEDA 422
Query: 190 DDVVYHNYFDVSMAVSTPRGLV 255
++ Y ++ +AV TP GLV
Sbjct: 423 QRLILKKYINIGVAVDTPNGLV 444
Score = 33.1 bits (72), Expect = 6.6
Identities = 19/54 (35%), Positives = 32/54 (59%), Gaps = 3/54 (5%)
Frame = +2
Query: 470 RSSDGGEWSG*D-PPMMYL--ALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
+SS W+G + P + L +LS+DHR+IDG + F+ + +L D RL++
Sbjct: 514 KSSMEPVWNGKEFAPRLILPMSLSFDHRVIDGADGARFISYLGSVLADLRRLVM 567
>UniRef50_UPI000150A9DD Cluster: pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase family protein; n=1;
Tetrahymena thermophila SB210|Rep: pyruvate
dehydrogenase complex dihydrolipoamide acetyltransferase
family protein - Tetrahymena thermophila SB210
Length = 646
Score = 59.7 bits (138), Expect = 7e-08
Identities = 30/79 (37%), Positives = 44/79 (55%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP++ + +TLG++ I K KELA K G L + GG FTI+N G++G I+NP
Sbjct: 519 TPIVFNAETLGLSQISSKTKELAEKARKGGLLPTEYQGGTFTISNLGMYGIDHFAAIVNP 578
Query: 435 PQSAILGMHAIKDRPMAVN 491
P IL + A + + N
Sbjct: 579 PHGTILAVGATSQKVVPDN 597
Score = 38.7 bits (86), Expect = 0.13
Identities = 24/74 (32%), Positives = 36/74 (48%)
Frame = +1
Query: 34 EVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNY 213
+V M ++ LRK E + + VKA AL+ P VN+ GD + +
Sbjct: 449 DVQMDEVLHLRKTLNEQSTSKISVN----DLIVKASALALRDMPGVNSQWHGDHIRQFKH 504
Query: 214 FDVSMAVSTPRGLV 255
DV++AVST GL+
Sbjct: 505 ADVAVAVSTKTGLI 518
>UniRef50_UPI0000E4A22B Cluster: PREDICTED: similar to pyruvate
dehydrogenase complex, component X; n=4;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
pyruvate dehydrogenase complex, component X -
Strongylocentrotus purpuratus
Length = 482
Score = 59.7 bits (138), Expect = 7e-08
Identities = 24/68 (35%), Positives = 44/68 (64%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP+++ D G+ +I +++LA + KL +++ GG+F+I+N G+FG + +INP
Sbjct: 362 TPIVKGADAKGLMEISANVRDLATRARANKLKLDEFQGGSFSISNLGMFGISEFSAVINP 421
Query: 435 PQSAILGM 458
PQS I+ +
Sbjct: 422 PQSCIMAI 429
Score = 44.0 bits (99), Expect = 0.004
Identities = 25/74 (33%), Positives = 40/74 (54%)
Frame = +1
Query: 34 EVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNY 213
+ + I+ LRKQ K+ I++ F +KA ALK+ PEVN + +G +
Sbjct: 293 DCELTEIVRLRKQL-----KKDNIKVSVNDFIIKAAAMALKQVPEVNVTWNGQSATPLSS 347
Query: 214 FDVSMAVSTPRGLV 255
D+S+AV+T GL+
Sbjct: 348 IDISVAVATDGGLI 361
>UniRef50_Q5WE92 Cluster: Acetoin dehydrogenase E2 component; n=1;
Bacillus clausii KSM-K16|Rep: Acetoin dehydrogenase E2
component - Bacillus clausii (strain KSM-K16)
Length = 410
Score = 59.7 bits (138), Expect = 7e-08
Identities = 29/83 (34%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R+ D L + + KI+++A G+ ++L+G FTITN G TPI+NP
Sbjct: 288 PVIRNADHLSIGQLATKIEKIAANARSGQSNPDELSGSTFTITNLGASSIEYFTPILNPA 347
Query: 438 QSAILGMHAI-KDRPMAVNGQVE 503
++ ILG+ ++ ++ ++ +GQVE
Sbjct: 348 ETGILGVGSLQQELALSEDGQVE 370
>UniRef50_Q1NYU2 Cluster: Dihydrolipoamide acyltransferase E2
component; n=1; Candidatus Sulcia muelleri str. Hc
(Homalodisca coagulata)|Rep: Dihydrolipoamide
acyltransferase E2 component - Candidatus Sulcia
muelleri str. Hc (Homalodisca coagulata)
Length = 371
Score = 59.7 bits (138), Expect = 7e-08
Identities = 30/83 (36%), Positives = 47/83 (56%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+ V+ + I +IKE +K + K+ +L G FT++N G+FG T IIN P
Sbjct: 250 PVINQVNEKSLRQISFEIKEKVIKAKEKKIQSNELEGSTFTVSNLGMFGIDSFTSIINQP 309
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
S IL + +IK +P+ N ++ I
Sbjct: 310 NSCILSVGSIKKKPIINNDKIVI 332
Score = 43.2 bits (97), Expect = 0.006
Identities = 24/76 (31%), Positives = 41/76 (53%)
Frame = +1
Query: 28 FNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYH 207
F EV M ++ LR E K++ ++ F VKA A+K P++N+S ++YH
Sbjct: 176 FIEVIMDNLIKLRDSINE---KKYLDKISFNDLIVKASALAIKENPKINSSWTEKSILYH 232
Query: 208 NYFDVSMAVSTPRGLV 255
N ++ +AV+ GL+
Sbjct: 233 NNINIGIAVALEDGLI 248
Score = 33.1 bits (72), Expect = 6.6
Identities = 12/32 (37%), Positives = 23/32 (71%)
Frame = +2
Query: 527 LSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
L+ DHR+IDG +L ++K+LL++P +++
Sbjct: 340 LTCDHRIIDGAVGSDYLKSLKKLLQEPLNIII 371
>UniRef50_Q0VRX7 Cluster: Pyruvate dehydrogenase, E2 component; n=4;
Proteobacteria|Rep: Pyruvate dehydrogenase, E2 component
- Alcanivorax borkumensis (strain SK2 / ATCC 700651 /
DSM 11573)
Length = 564
Score = 59.7 bits (138), Expect = 7e-08
Identities = 30/75 (40%), Positives = 46/75 (61%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV++D D G+ I +++ ELA K + KLT D+ GG F+I++ G G TPI+N P
Sbjct: 443 PVIKDADKKGLKAIAQEMDELAEKARNRKLTPADMKGGTFSISSLGGIGGTAFTPIVNWP 502
Query: 438 QSAILGMHAIKDRPM 482
+ AILG+ +P+
Sbjct: 503 EVAILGVSRSDMQPV 517
Score = 52.0 bits (119), Expect = 1e-05
Identities = 26/81 (32%), Positives = 45/81 (55%), Gaps = 2/81 (2%)
Frame = +1
Query: 19 LTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID--GD 192
+T + ++ + RK + E R G++L ++F V A ALK YP N+S++ G+
Sbjct: 362 VTQHDNADITDLEAFRKSQNKRLE-REGVKLTMLAFLVAACARALKEYPRFNSSLENSGE 420
Query: 193 DVVYHNYFDVSMAVSTPRGLV 255
++ Y ++ +AV TP GLV
Sbjct: 421 ALIEKRYINIGIAVDTPNGLV 441
Score = 34.7 bits (76), Expect = 2.2
Identities = 15/34 (44%), Positives = 22/34 (64%)
Frame = +2
Query: 521 LALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
++LSYDHR+IDG + F + +LL D + LL
Sbjct: 531 MSLSYDHRVIDGAAAARFTTYLSQLLTDMRQALL 564
>UniRef50_A6W003 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Marinomonas|Rep: Catalytic
domain of components of various dehydrogenase complexes
- Marinomonas sp. MWYL1
Length = 414
Score = 59.7 bits (138), Expect = 7e-08
Identities = 34/87 (39%), Positives = 51/87 (58%), Gaps = 3/87 (3%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTP-IINP 434
PV++ V + +I +++ K GKL D+ G FTI+N GV GSL +TP IIN
Sbjct: 291 PVVKQVQEKNLFEIASALQQQTDKARQGKLAAADMRDGTFTISNHGVSGSLFATPIIINQ 350
Query: 435 PQSAILGMHAIKDRPMA--VNGQVEIL 509
PQ AILG+ ++ R + V+G+ I+
Sbjct: 351 PQVAILGIGKLEKRAVVEEVDGEDTIV 377
>UniRef50_A4XEQ9 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Sphingomonadaceae|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Novosphingobium aromaticivorans (strain DSM
12444)
Length = 480
Score = 59.7 bits (138), Expect = 7e-08
Identities = 31/83 (37%), Positives = 46/83 (55%), Gaps = 1/83 (1%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP++R D + +A I + L K G+L ED+ GG F+++N G+FG IINP
Sbjct: 357 TPIVRQADRMHIAQIAATTRALIDKAQAGRLGYEDMDGGTFSVSNLGMFGIEQFDAIINP 416
Query: 435 PQSAILGMHAIKDRPM-AVNGQV 500
PQ AIL + + + A NG +
Sbjct: 417 PQGAILAVGGVNRVAVEAANGDI 439
Score = 48.8 bits (111), Expect = 1e-04
Identities = 27/68 (39%), Positives = 39/68 (57%)
Frame = +1
Query: 52 IMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMA 231
+MDLRK G + + VKAV AL R+P+VN + GD V + DV++A
Sbjct: 293 LMDLRKTANLVL----GTKASINDYLVKAVALALVRHPDVNVQVHGDSVHSFPHADVAIA 348
Query: 232 VSTPRGLV 255
V++P+GLV
Sbjct: 349 VASPKGLV 356
Score = 34.7 bits (76), Expect = 2.2
Identities = 17/32 (53%), Positives = 19/32 (59%)
Frame = +2
Query: 521 LALSYDHRLIDGRESVGFLVTIKELLEDPTRL 616
L +S DHR IDG FL T+K LLE P L
Sbjct: 447 LTMSVDHRAIDGAAGAKFLQTLKGLLEAPEGL 478
>UniRef50_Q6L1M0 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex; n=2;
Thermoplasmatales|Rep: Dihydrolipoamide
acetyltransferase component of pyruvate dehydrogenase
complex - Picrophilus torridus
Length = 386
Score = 59.7 bits (138), Expect = 7e-08
Identities = 28/67 (41%), Positives = 43/67 (64%)
Frame = +3
Query: 261 VLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPPQ 440
V++DVD + +I +I+ELA K KL ++D+ F++TN G G + STPIIN P+
Sbjct: 269 VVKDVDKKSIFEISMEIRELAEKARSNKLEMDDVRDSTFSVTNIGAIGGIYSTPIINYPE 328
Query: 441 SAILGMH 461
AIL ++
Sbjct: 329 VAILAVN 335
Score = 39.9 bits (89), Expect = 0.058
Identities = 16/31 (51%), Positives = 23/31 (74%)
Frame = +2
Query: 515 MYLALSYDHRLIDGRESVGFLVTIKELLEDP 607
+Y+ L+ DHRLIDG E+ F+ IKE++E P
Sbjct: 350 VYVTLACDHRLIDGAEAARFIKKIKEIIEQP 380
>UniRef50_P21883 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=80; Bacilli|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex - Bacillus subtilis
Length = 442
Score = 59.7 bits (138), Expect = 7e-08
Identities = 29/81 (35%), Positives = 48/81 (59%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+++ D + +I +I LA K +GKL ++ G + TITN G G TP+IN P
Sbjct: 319 PVVKNADRKSVFEISDEINGLATKAREGKLAPAEMKGASCTITNIGSAGGQWFTPVINHP 378
Query: 438 QSAILGMHAIKDRPMAVNGQV 500
+ AILG+ I ++ + +G++
Sbjct: 379 EVAILGIGRIAEKAIVRDGEI 399
Score = 59.3 bits (137), Expect = 9e-08
Identities = 29/87 (33%), Positives = 56/87 (64%), Gaps = 2/87 (2%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
K++ +T +EV++ ++ RKQ+ + + GI+L ++ + VKA+ ALK++P +N S
Sbjct: 232 KHTAPHVTLMDEVDVTNLVAHRKQFKQVAADQ-GIKLTYLPYVVKALTSALKKFPVLNTS 290
Query: 181 IDG--DDVVYHNYFDVSMAVSTPRGLV 255
ID D+V+ +YF++ +A T +GL+
Sbjct: 291 IDDKTDEVIQKHYFNIGIAADTEKGLL 317
Score = 41.1 bits (92), Expect = 0.025
Identities = 18/39 (46%), Positives = 27/39 (69%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
P++ L+LS+DHR+IDG + L IK LL DP +L++
Sbjct: 403 PVLALSLSFDHRMIDGATAQNALNHIKRLLNDPQLILME 441
>UniRef50_Q15U82 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=3; Gammaproteobacteria|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Pseudoalteromonas atlantica (strain T6c /
BAA-1087)
Length = 555
Score = 59.3 bits (137), Expect = 9e-08
Identities = 26/74 (35%), Positives = 46/74 (62%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
P ++ V + + DI K+ EL + +G+L D++GG +I+N GV G ++TP+IN P
Sbjct: 430 PNIKGVQDMSIFDIAKRASELIEQAREGRLRTADISGGTISISNIGVLGGTVATPVINHP 489
Query: 438 QSAILGMHAIKDRP 479
++AI+ + I+ P
Sbjct: 490 EAAIVALGKIQRLP 503
Score = 53.6 bits (123), Expect = 4e-06
Identities = 27/80 (33%), Positives = 46/80 (57%), Gaps = 2/80 (2%)
Frame = +1
Query: 22 TTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGD--D 195
T E+ M ++ LR Q + F ++ G++L FM F++KA+ ALK YP +N+ ++ D
Sbjct: 350 TVSEEIQMDALIALRSQLKDDFSEQ-GVKLSFMPFFIKALSLALKAYPVINSQVNDDCTQ 408
Query: 196 VVYHNYFDVSMAVSTPRGLV 255
+ Y N ++ AV GL+
Sbjct: 409 LTYFNEHNIGFAVDGKLGLM 428
>UniRef50_A5IXN4 Cluster: Dihydrolipoamide acetyltransferase
component ofpyruvate deshydrogenase complex; n=1;
Mycoplasma agalactiae|Rep: Dihydrolipoamide
acetyltransferase component ofpyruvate deshydrogenase
complex - Mycoplasma agalactiae
Length = 244
Score = 59.3 bits (137), Expect = 9e-08
Identities = 31/72 (43%), Positives = 43/72 (59%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R V+ L + DI+K+I L+ D KL + D++GG F ITN G G L +PI+N
Sbjct: 121 PVIRGVENLSIIDIQKEIVRLSTLARDKKLKMSDMSGGCFAITNVGSAGVLFGSPIMNKG 180
Query: 438 QSAILGMHAIKD 473
+AI AI D
Sbjct: 181 NTAISATGAIID 192
Score = 43.2 bits (97), Expect = 0.006
Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Frame = +1
Query: 7 STAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID 186
S+A + + ++ + +LR + + H ++L F+S+ VKA AL YP A D
Sbjct: 35 SSAYCSLVLKADVTNLWNLRAKVKDKVFAEHNVKLTFLSWIVKASAIALSEYPSFAARWD 94
Query: 187 GDD--VVYHNYFDVSMAVSTPRGL 252
G + V Y ++ +AV TP GL
Sbjct: 95 GVEGKVYYPGTLNIGIAVDTPFGL 118
Score = 37.1 bits (82), Expect = 0.41
Identities = 15/35 (42%), Positives = 25/35 (71%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRL 616
+MYL+++ DH+ +DG + F IKEL+E+P +L
Sbjct: 207 VMYLSIAADHQWVDGADMARFQGRIKELIENPEQL 241
>UniRef50_A4SZ52 Cluster: Catalytic domain of components of various
dehydrogenase complexes precursor; n=1; Polynucleobacter
sp. QLW-P1DMWA-1|Rep: Catalytic domain of components of
various dehydrogenase complexes precursor -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 472
Score = 59.3 bits (137), Expect = 9e-08
Identities = 30/75 (40%), Positives = 44/75 (58%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R+ D G+ +I K+ ELA DGKL E + G +FTI++ G G PIIN P
Sbjct: 351 PVIRNADQKGILEIAKETAELAQLARDGKLKPEQMQGASFTISSLGGIGGTYCAPIINAP 410
Query: 438 QSAILGMHAIKDRPM 482
+ AIL ++ +P+
Sbjct: 411 EVAILAVNKSAIKPV 425
Score = 54.0 bits (124), Expect = 3e-06
Identities = 22/55 (40%), Positives = 36/55 (65%)
Frame = +1
Query: 91 KRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLV 255
K+ +++ ++F +KA V ALK+YP NAS+DG++++ Y + AV T GLV
Sbjct: 295 KKDAVKITLLAFLIKAAVAALKKYPTFNASLDGEELILKKYCHIGFAVDTNIGLV 349
>UniRef50_Q4Q1F5 Cluster: Dihydrolipoamide acetyltransferase,
putative; n=6; Trypanosomatidae|Rep: Dihydrolipoamide
acetyltransferase, putative - Leishmania major
Length = 463
Score = 59.3 bits (137), Expect = 9e-08
Identities = 30/81 (37%), Positives = 44/81 (54%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP++R+ G+ +I K+ K LA K DG L + GG +++N G G T IINP
Sbjct: 333 TPIIRNAQAKGLVEISKETKALAKKARDGTLQPSEFQGGTCSVSNLGATGIPGFTAIINP 392
Query: 435 PQSAILGMHAIKDRPMAVNGQ 497
PQ+ IL + + K R V +
Sbjct: 393 PQAMILAVGSAKPRAEIVKSE 413
Score = 41.9 bits (94), Expect = 0.014
Identities = 26/76 (34%), Positives = 40/76 (52%)
Frame = +1
Query: 28 FNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYH 207
F++ + ++ L KQ + I + + VKAV A PEVN+S GD + +
Sbjct: 259 FDDCRVDNMLALIKQLNAKGNGEYKITVN--DYIVKAVARANTLVPEVNSSWQGDFIRQY 316
Query: 208 NYFDVSMAVSTPRGLV 255
DVS+AV+TP GL+
Sbjct: 317 ATVDVSVAVATPTGLI 332
>UniRef50_O59816 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=1;
Schizosaccharomyces pombe|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex, mitochondrial
precursor - Schizosaccharomyces pombe (Fission yeast)
Length = 483
Score = 59.3 bits (137), Expect = 9e-08
Identities = 30/73 (41%), Positives = 42/73 (57%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TPV+R+ LG+A+I K+ + + KL E+ GG FTI+N G+F T IINP
Sbjct: 358 TPVIRNTHALGLAEISTLAKDYGQRARNNKLKPEEYQGGTFTISNLGMFPVDQFTAIINP 417
Query: 435 PQSAILGMHAIKD 473
PQ+ IL + D
Sbjct: 418 PQACILAVGTTVD 430
Score = 50.8 bits (116), Expect = 3e-05
Identities = 28/73 (38%), Positives = 42/73 (57%)
Frame = +1
Query: 37 VNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYF 216
VNM+ I+ LR + R+ +L +KA AL++ PEVNA+ GD + +
Sbjct: 287 VNMEKIIRLRAALNAMADGRY--KLSVNDLVIKATTAALRQVPEVNAAWMGDFIRQYKNV 344
Query: 217 DVSMAVSTPRGLV 255
D+SMAV+TP GL+
Sbjct: 345 DISMAVATPSGLI 357
Score = 38.7 bits (86), Expect = 0.13
Identities = 15/38 (39%), Positives = 25/38 (65%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
P+M LS DHR++DG + F +K++LE+P ++L
Sbjct: 446 PIMKCTLSSDHRVVDGAMAARFTTALKKILENPLEIML 483
>UniRef50_UPI0000D56122 Cluster: PREDICTED: similar to Lipoamide
acyltransferase component of branched-chain alpha-keto
acid dehydrogenase complex, mitochondrial precursor
(Dihydrolipoyllysine-residue
(2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide
branched chain transacylase) (BCKAD ...; n=1; Tribolium
castaneum|Rep: PREDICTED: similar to Lipoamide
acyltransferase component of branched-chain alpha-keto
acid dehydrogenase complex, mitochondrial precursor
(Dihydrolipoyllysine-residue
(2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide
branched chain transacylase) (BCKAD ... - Tribolium
castaneum
Length = 429
Score = 58.8 bits (136), Expect = 1e-07
Identities = 26/69 (37%), Positives = 40/69 (57%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+++V+TL + +I ++ L G G + +DL GG FTI+N G G P+I PP
Sbjct: 305 PVIKNVETLSIIEISNELNRLIKSGRSGSFSPQDLAGGTFTISNIGAIGGTYMKPVIMPP 364
Query: 438 QSAILGMHA 464
AI+ + A
Sbjct: 365 HVAIVALGA 373
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/76 (31%), Positives = 46/76 (60%), Gaps = 2/76 (2%)
Frame = +1
Query: 31 NEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDG--DDVVY 204
+E+ + + LR+ + E + ++L FM F++KA AL+R+P +NAS+D ++V Y
Sbjct: 228 DEIAVTQLSQLRQTLKKLPETQD-LKLSFMPFFIKAASNALQRFPVLNASLDENCENVTY 286
Query: 205 HNYFDVSMAVSTPRGL 252
+ ++ +A+ T GL
Sbjct: 287 KSEHNIGVAMDTKVGL 302
>UniRef50_Q98PG1 Cluster: DIHYDROLIPOAMIDE ACETYLTRANSFERASE
COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX; n=1;
Mycoplasma pulmonis|Rep: DIHYDROLIPOAMIDE
ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE
COMPLEX - Mycoplasma pulmonis
Length = 315
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/79 (37%), Positives = 45/79 (56%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+++ +L + + ++I LA + D++G FTITN G GSL TP+IN P
Sbjct: 193 PVIKNAQSLNLVEFSQEIIRLANLARTKTIKPADMSGATFTITNYGSVGSLFGTPVINYP 252
Query: 438 QSAILGMHAIKDRPMAVNG 494
+ AI G+ AI D+ NG
Sbjct: 253 ELAIAGVGAIVDKVYWKNG 271
Score = 48.4 bits (110), Expect = 2e-04
Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 2/87 (2%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+++ A ++ +E++M + DLRK E + GI+L F+ F +KA+ A+K + A
Sbjct: 105 QDNVAYVSLVHEIDMTKLWDLRKSVVEKVKDLTGIKLTFLPFILKAIAIAIKDFQIFGAK 164
Query: 181 ID--GDDVVYHNYFDVSMAVSTPRGLV 255
D +++VY + ++ +AV T GL+
Sbjct: 165 YDEKTEELVYPDTVNLGVAVDTDHGLM 191
>UniRef50_A0H5V3 Cluster: Dihydrolipoamide S-succinyltransferase;
n=1; Chloroflexus aggregans DSM 9485|Rep:
Dihydrolipoamide S-succinyltransferase - Chloroflexus
aggregans DSM 9485
Length = 435
Score = 58.8 bits (136), Expect = 1e-07
Identities = 27/83 (32%), Positives = 50/83 (60%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+RD D ++ I +I+++A++ +GK+ +L G F +TN G+FG + II+ P
Sbjct: 314 PVVRDADKKSVSTISAEIRDMALRAREGKIKQNELEGATFQVTNLGMFGIIEFGSIISVP 373
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
Q+A L + ++ P+ + Q+ I
Sbjct: 374 QAASLAVGTVRKVPVVRDDQIVI 396
Score = 35.5 bits (78), Expect = 1.2
Identities = 15/37 (40%), Positives = 24/37 (64%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
+M L LS DHR+IDG +L +++LLE P +++
Sbjct: 399 VMNLTLSADHRVIDGAVGAQYLQELRKLLESPVSIIV 435
>UniRef50_A2WKX8 Cluster: Putative uncharacterized protein; n=1;
Oryza sativa (indica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. indica
(Rice)
Length = 409
Score = 58.8 bits (136), Expect = 1e-07
Identities = 29/65 (44%), Positives = 40/65 (61%), Gaps = 1/65 (1%)
Frame = +3
Query: 267 RDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITN-GGVFGSLMSTPIINPPQS 443
+D + G+A I ++K+LA + D L ED GG FT++N GG FG I+NPPQS
Sbjct: 249 KDAEKKGLATIVDQVKQLAQRARDNSLKPEDYEGGTFTVSNLGGPFGIKQFRAIVNPPQS 308
Query: 444 AILGM 458
AIL +
Sbjct: 309 AILAI 313
>UniRef50_A0CWR1 Cluster: Chromosome undetermined scaffold_3, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_3,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 628
Score = 58.8 bits (136), Expect = 1e-07
Identities = 29/68 (42%), Positives = 41/68 (60%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP++ + + G+ I +KELA K KL ++ GG FTI+N G+FG +INP
Sbjct: 505 TPIVFNAGSKGLGTIASTVKELADKAKANKLKPQEFIGGTFTISNLGMFGIDQFIAVINP 564
Query: 435 PQSAILGM 458
PQSAIL +
Sbjct: 565 PQSAILAV 572
Score = 35.9 bits (79), Expect = 0.94
Identities = 21/73 (28%), Positives = 34/73 (46%)
Frame = +1
Query: 37 VNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYF 216
+ M MD + E K +++ F +KA ALK P+ N+ G +
Sbjct: 432 LTMTVTMDKVLKVREELNKLQKVKISVNDFIIKASALALKDVPQANSQWHGTYIRKFANA 491
Query: 217 DVSMAVSTPRGLV 255
D+S+AV+T GL+
Sbjct: 492 DISIAVATDAGLI 504
Score = 33.9 bits (74), Expect = 3.8
Identities = 16/36 (44%), Positives = 21/36 (58%)
Frame = +2
Query: 515 MYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
M + LS DHR++DG +L K +EDP LLL
Sbjct: 593 MDVTLSCDHRVVDGAVGAQWLQRFKYYIEDPNTLLL 628
>UniRef50_P10515 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=46; cellular
organisms|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor - Homo sapiens (Human)
Length = 614
Score = 58.8 bits (136), Expect = 1e-07
Identities = 29/74 (39%), Positives = 43/74 (58%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP++ + G+ I + LA K +GKL + GG FTI+N G+FG + IINP
Sbjct: 490 TPIVFNAHIKGVETIANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINP 549
Query: 435 PQSAILGMHAIKDR 476
PQ+ IL + A +D+
Sbjct: 550 PQACILAIGASEDK 563
Score = 44.4 bits (100), Expect = 0.003
Identities = 29/75 (38%), Positives = 43/75 (57%), Gaps = 1/75 (1%)
Frame = +1
Query: 34 EVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNY 213
+VNM ++ +RK+ + E R I + F +KA A + PE N+S D V+ N+
Sbjct: 418 DVNMGEVLLVRKELNKILEGRSKISVN--DFIIKASALACLKVPEANSSWM-DTVIRQNH 474
Query: 214 F-DVSMAVSTPRGLV 255
DVS+AVSTP GL+
Sbjct: 475 VVDVSVAVSTPAGLI 489
Score = 33.9 bits (74), Expect = 3.8
Identities = 15/37 (40%), Positives = 22/37 (59%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
MM + LS DHR++DG +L ++ LE P +LL
Sbjct: 578 MMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPITMLL 614
>UniRef50_P06959 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=62; Proteobacteria|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Escherichia coli
(strain K12)
Length = 630
Score = 58.8 bits (136), Expect = 1e-07
Identities = 26/67 (38%), Positives = 44/67 (65%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV +DV+ G+ ++ +++ ++ K DGKLT ++ GG FTI++ G G+ PI+N P
Sbjct: 509 PVFKDVNKKGIIELSRELMTISKKARDGKLTAGEMQGGCFTISSIGGLGTTHFAPIVNAP 568
Query: 438 QSAILGM 458
+ AILG+
Sbjct: 569 EVAILGV 575
Score = 48.4 bits (110), Expect = 2e-04
Identities = 27/82 (32%), Positives = 46/82 (56%), Gaps = 3/82 (3%)
Frame = +1
Query: 19 LTTFNEVNMKPIMDLRKQYGEAFEKRH-GIRLGFMSFYVKAVVEALKRYPEVNASI--DG 189
+T F++ ++ + RKQ E KR +++ + F +KAV AL++ P N+S+ DG
Sbjct: 426 VTHFDKTDITELEAFRKQQNEEAAKRKLDVKITPVVFIMKAVAAALEQMPRFNSSLSEDG 485
Query: 190 DDVVYHNYFDVSMAVSTPRGLV 255
+ Y ++ +AV TP GLV
Sbjct: 486 QRLTLKKYINIGVAVDTPNGLV 507
Score = 36.7 bits (81), Expect = 0.54
Identities = 15/37 (40%), Positives = 24/37 (64%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
M+ ++LS+DHR+IDG + F+ I L D RL++
Sbjct: 594 MLPISLSFDHRVIDGADGARFITIINNTLSDIRRLVM 630
>UniRef50_Q6A613 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex; n=1;
Propionibacterium acnes|Rep: Dihydrolipoamide
acetyltransferase component of pyruvate dehydrogenase
complex - Propionibacterium acnes
Length = 469
Score = 58.4 bits (135), Expect = 2e-07
Identities = 33/89 (37%), Positives = 46/89 (51%), Gaps = 3/89 (3%)
Frame = +3
Query: 231 GFYAARPG---TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVF 401
G AA P PV+RD + M ++ +I + + KL D G F+ITN GVF
Sbjct: 331 GIAAATPRGLMVPVVRDAQDMAMLELATEITRIVAIAKEDKLQPPDYADGTFSITNVGVF 390
Query: 402 GSLMSTPIINPPQSAILGMHAIKDRPMAV 488
G TP++N +SAIL + A+ RP V
Sbjct: 391 GLDAGTPVVNRTESAILVLGALARRPWVV 419
Score = 48.0 bits (109), Expect = 2e-04
Identities = 26/86 (30%), Positives = 52/86 (60%), Gaps = 2/86 (2%)
Frame = +1
Query: 4 NSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASI 183
++ A++T F ++ P M+L + A + G+R+ ++ + KAV A+ R P +NA+
Sbjct: 257 DTKALVTAFLTCDVTPTMELVNRL-RADRRFKGLRVSPLTVWCKAVCLAMGRTPIINAAW 315
Query: 184 D--GDDVVYHNYFDVSMAVSTPRGLV 255
D D +V+ ++ ++ +A +TPRGL+
Sbjct: 316 DDAADQIVFRDHINLGIAAATPRGLM 341
Score = 37.5 bits (83), Expect = 0.31
Identities = 15/34 (44%), Positives = 22/34 (64%)
Frame = +2
Query: 521 LALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
++L +DHRLIDG + FL + E+L DP +L
Sbjct: 435 MSLGFDHRLIDGEQGSTFLHDVAEILSDPASAML 468
>UniRef50_Q0SGE5 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=3; Actinomycetales|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Rhodococcus sp. (strain RHA1)
Length = 417
Score = 58.0 bits (134), Expect = 2e-07
Identities = 32/86 (37%), Positives = 47/86 (54%), Gaps = 3/86 (3%)
Frame = +3
Query: 231 GFYAARPG---TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVF 401
G AA P P +++ +L + ++ + I EL G+ LTGG +ITN GVF
Sbjct: 282 GIAAATPRGLVVPNIKEAQSLSLLELCRAITELTATARSGRAEPAQLTGGTVSITNVGVF 341
Query: 402 GSLMSTPIINPPQSAILGMHAIKDRP 479
G TPI+NP +SAIL + ++ RP
Sbjct: 342 GVDAGTPILNPGESAILCLGSVTRRP 367
Score = 40.3 bits (90), Expect = 0.044
Identities = 20/54 (37%), Positives = 35/54 (64%), Gaps = 2/54 (3%)
Frame = +1
Query: 100 GIRLGFMSFYVKAVVEALKRYPEVNASIDGD--DVVYHNYFDVSMAVSTPRGLV 255
G+ + +S KA++ AL+ P +NAS D + ++V +Y ++ +A +TPRGLV
Sbjct: 239 GLSVTPLSLVAKAMIVALRENPSLNASWDEENQEIVTKHYVNLGIAAATPRGLV 292
Score = 37.1 bits (82), Expect = 0.41
Identities = 14/33 (42%), Positives = 23/33 (69%)
Frame = +2
Query: 521 LALSYDHRLIDGRESVGFLVTIKELLEDPTRLL 619
L++S+DHR++DG + FL ++ +L DP LL
Sbjct: 382 LSVSFDHRVVDGEQGSRFLSSVAAMLHDPASLL 414
>UniRef50_A3WJV9 Cluster: Apha keto acid dehydrogenase complex, E2
component; n=2; Alteromonadales|Rep: Apha keto acid
dehydrogenase complex, E2 component - Idiomarina baltica
OS145
Length = 515
Score = 58.0 bits (134), Expect = 2e-07
Identities = 27/82 (32%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
P ++ V + D+ ++ L +GK+ D+ GG +I+N GV G ++TPIIN P
Sbjct: 390 PNVKQVQNKSIIDVANEVTRLTQAAREGKVPQADMKGGTISISNIGVIGGTVATPIINKP 449
Query: 438 QSAILGMHAIKDRP-MAVNGQV 500
++AI+ + +++ P NGQV
Sbjct: 450 EAAIVALGKVQELPRFDANGQV 471
Score = 51.2 bits (117), Expect = 2e-05
Identities = 28/80 (35%), Positives = 49/80 (61%), Gaps = 2/80 (2%)
Frame = +1
Query: 22 TTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGD--D 195
T +E ++ ++ LR++ E + K G+RL M F++KA+ ALK +P +NA ++ D +
Sbjct: 310 TYSDEFDLTNLIALREKLKEQY-KEQGVRLTVMPFFIKALSLALKEFPIMNAQVNDDCTE 368
Query: 196 VVYHNYFDVSMAVSTPRGLV 255
V Y + ++ MAV T GL+
Sbjct: 369 VTYFDDHNIGMAVDTKIGLL 388
Score = 35.1 bits (77), Expect = 1.6
Identities = 17/39 (43%), Positives = 25/39 (64%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
MM ++ S DHR+IDG F +E LEDPT +L+++
Sbjct: 476 MMTVSWSGDHRIIDGGTIARFNKRWQEFLEDPTSMLVNM 514
>UniRef50_Q6F713 Cluster: Dihydrolipoamide S-acetyltransferase, E2
component of the pyruvate dehydrogenase complex; n=2;
Moraxellaceae|Rep: Dihydrolipoamide S-acetyltransferase,
E2 component of the pyruvate dehydrogenase complex -
Acinetobacter sp. (strain ADP1)
Length = 661
Score = 57.6 bits (133), Expect = 3e-07
Identities = 36/99 (36%), Positives = 52/99 (52%), Gaps = 4/99 (4%)
Frame = +3
Query: 198 GLPQLFRRQ-HGGFYAARPG---TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLT 365
G L R++ H G A P PVLR+ D + I ++ + K D KL+ +DL
Sbjct: 516 GKSVLLRKEIHMGIAVATPDGLTVPVLRNPDQKTIKQIAVELGVIGQKARDKKLSPKDLQ 575
Query: 366 GGNFTITNGGVFGSLMSTPIINPPQSAILGMHAIKDRPM 482
G NFTI++ G G TP++N PQ AILG+ +P+
Sbjct: 576 GANFTISSLGAIGGTAFTPLVNWPQVAILGISPATMQPV 614
Score = 37.9 bits (84), Expect = 0.23
Identities = 22/56 (39%), Positives = 30/56 (53%), Gaps = 2/56 (3%)
Frame = +1
Query: 91 KRHGIRLGFMSFYVKAVVEALKRYPEV--NASIDGDDVVYHNYFDVSMAVSTPRGL 252
K+ GI L M+F +KAV LK E + S DG V+ + +AV+TP GL
Sbjct: 482 KKEGISLTIMAFIIKAVAHLLKEEREFAGHLSDDGKSVLLRKEIHMGIAVATPDGL 537
Score = 37.1 bits (82), Expect = 0.41
Identities = 20/47 (42%), Positives = 31/47 (65%), Gaps = 3/47 (6%)
Frame = +2
Query: 491 WSG*D--PPMMY-LALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
W+G D P +M L+LSYDHR+I+G ++ F + +LL+D LL+
Sbjct: 615 WNGKDFDPRLMLPLSLSYDHRVINGADAARFTNKLTKLLQDIRSLLI 661
>UniRef50_Q2B858 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillus
sp. NRRL B-14911|Rep: Pyruvate dehydrogenase E2 -
Bacillus sp. NRRL B-14911
Length = 391
Score = 57.6 bits (133), Expect = 3e-07
Identities = 35/109 (32%), Positives = 57/109 (52%), Gaps = 4/109 (3%)
Frame = +3
Query: 198 GLPQLFRRQHGGFYA-ARPG--TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTG 368
GL L H G A G PV+ + + +A+I + ++ L K DG+L ++ G
Sbjct: 242 GLIHLLPEHHIGVAVNAEDGLIVPVIGNAEEKTIAEIAEDLQNLTRKALDGRLLAKETAG 301
Query: 369 GNFTITN-GGVFGSLMSTPIINPPQSAILGMHAIKDRPMAVNGQVEILR 512
G FT++N G + GS +TPII PQ++I+ +H K P+ ++R
Sbjct: 302 GTFTVSNVGPLNGSTGATPIILHPQTSIISLHKTKKMPVVDKDDQIVIR 350
Score = 41.5 bits (93), Expect = 0.019
Identities = 17/39 (43%), Positives = 28/39 (71%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
+M L++S+DHR+ DG +VGF EL+E+P +LL++
Sbjct: 352 IMKLSMSFDHRIADGAAAVGFTNRFAELIENPKLMLLEL 390
>UniRef50_A1SYC2 Cluster: Dihydrolipoamide dehydrogenase E3
component of 3 enzyme complexes; n=1; Psychromonas
ingrahamii 37|Rep: Dihydrolipoamide dehydrogenase E3
component of 3 enzyme complexes - Psychromonas
ingrahamii (strain 37)
Length = 431
Score = 57.6 bits (133), Expect = 3e-07
Identities = 30/84 (35%), Positives = 45/84 (53%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP++ + D G+ + + +K L K GKL + GG FTI+N G++ IINP
Sbjct: 305 TPIVFNADRKGLITLSQNMKSLVSKTRSGKLQPNEYQGGGFTISNLGMYDIDSFNAIINP 364
Query: 435 PQSAILGMHAIKDRPMAVNGQVEI 506
PQS IL + K P+ + Q+ I
Sbjct: 365 PQSCILAVGRAKKIPVVKDDQILI 388
Score = 43.2 bits (97), Expect = 0.006
Identities = 20/65 (30%), Positives = 37/65 (56%)
Frame = +1
Query: 61 LRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVST 240
LR ++ ++ ++L F +KAV A+ ++PE+N+ + V + D+S+AVST
Sbjct: 240 LRAEFNAFYKDHENVKLTVNDFIIKAVALAIHKHPEINSMWLSEGVKKNKNIDISVAVST 299
Query: 241 PRGLV 255
GL+
Sbjct: 300 DDGLM 304
Score = 35.5 bits (78), Expect = 1.2
Identities = 16/37 (43%), Positives = 23/37 (62%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
+M LS DHR+IDG + FL T K +E+P ++L
Sbjct: 391 VMNCTLSVDHRVIDGSVAAEFLQTFKFYIENPKHMML 427
>UniRef50_Q1EGH6 Cluster: Pyruvate dehydrogenase E2 subunit; n=1;
Euplotes sp. BB-2004|Rep: Pyruvate dehydrogenase E2
subunit - Euplotes sp. BB-2004
Length = 459
Score = 57.6 bits (133), Expect = 3e-07
Identities = 24/74 (32%), Positives = 46/74 (62%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP++++ + G+ I ++K+LA + + KL +++ GG +++N G+FG + IINP
Sbjct: 335 TPIIKEANLKGLETISAEMKDLAARARENKLKLDEFQGGTISVSNLGMFGVSHFSAIINP 394
Query: 435 PQSAILGMHAIKDR 476
PQ+ IL + + R
Sbjct: 395 PQACILAIGGSQQR 408
Score = 40.7 bits (91), Expect = 0.033
Identities = 19/42 (45%), Positives = 28/42 (66%)
Frame = +1
Query: 130 VKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLV 255
+KA A K+ P+ N+S GD + ++ DVS+AVSTP GL+
Sbjct: 293 IKATSLASKKVPQTNSSWQGDFIRQYSNVDVSVAVSTPTGLI 334
>UniRef50_Q5Z123 Cluster: Putative branched-chain alpha-keto acid
dehydrogenase component; n=1; Nocardia farcinica|Rep:
Putative branched-chain alpha-keto acid dehydrogenase
component - Nocardia farcinica
Length = 510
Score = 57.2 bits (132), Expect = 4e-07
Identities = 30/83 (36%), Positives = 45/83 (54%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
P +++ L + ++ +I G T DLTGG FTITN GVFG P++NP
Sbjct: 387 PSVKEAHRLSLRELCAEIGRTIEAARAGTATPADLTGGTFTITNVGVFGVDSGVPLVNPG 446
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
++AIL + AI RP V ++ +
Sbjct: 447 EAAILCLGAIGRRPWVVADELAV 469
Score = 40.7 bits (91), Expect = 0.033
Identities = 19/33 (57%), Positives = 22/33 (66%)
Frame = +2
Query: 521 LALSYDHRLIDGRESVGFLVTIKELLEDPTRLL 619
L LS+DHRLIDG + FL T+ LL DP LL
Sbjct: 475 LGLSFDHRLIDGELAARFLATVAGLLTDPLTLL 507
Score = 33.1 bits (72), Expect = 6.6
Identities = 24/72 (33%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Frame = +1
Query: 100 GIRLGFMSFYVKAVVEALKRYPEVNASIDGD--DVVYHNYFDVSMAVSTPRGLVRRFCVM 273
G+ L + KAV+ AL +P VNA D + +V Y + +A +T RGL+ V
Sbjct: 332 GLSLTPLVVVAKAVLAALAEFPGVNAQWDEERQQIVTKRYVHLGIAAATDRGLL----VP 387
Query: 274 SIPSAWQTSRRK 309
S+ A + S R+
Sbjct: 388 SVKEAHRLSLRE 399
>UniRef50_Q3WAF9 Cluster: Biotin/lipoyl attachment:Catalytic domain
of components of various dehydrogenase complexes:E3
binding; n=2; Frankia|Rep: Biotin/lipoyl
attachment:Catalytic domain of components of various
dehydrogenase complexes:E3 binding - Frankia sp. EAN1pec
Length = 585
Score = 57.2 bits (132), Expect = 4e-07
Identities = 27/83 (32%), Positives = 44/83 (53%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
P + D + G+ D+ + + L +L DL+GG TITN GV G P++NP
Sbjct: 462 PNIPDAGSRGLVDLARSLHSLTEAARADRLRPADLSGGTITITNVGVLGVDTGAPVLNPG 521
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
++AIL + AI+ P G++ +
Sbjct: 522 EAAILALGAIRPAPWVHEGELAV 544
Score = 37.5 bits (83), Expect = 0.31
Identities = 29/95 (30%), Positives = 50/95 (52%), Gaps = 6/95 (6%)
Frame = +1
Query: 22 TTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGD--- 192
T F V++ M R++ A GIR+ + KA++ A++R+P +N++ GD
Sbjct: 378 TEFLSVDVTETMAARERIA-ALPDFAGIRVTPLLLVAKALLTAVRRHPMINSTWVGDTSG 436
Query: 193 ---DVVYHNYFDVSMAVSTPRGLVRRFCVMSIPSA 288
++ H ++ +AV+ PRGLV V +IP A
Sbjct: 437 ENAEIQVHERINLGIAVAGPRGLV----VPNIPDA 467
Score = 32.7 bits (71), Expect = 8.8
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = +2
Query: 518 YLALSYDHRLIDGRESVGFLVTIKELLEDP 607
+LALS+DHR++DG L + +L DP
Sbjct: 549 HLALSFDHRVVDGELGSAVLADVAAVLADP 578
>UniRef50_A6EAZ4 Cluster: Dihydrolipoyllysine-residue
acetyltransferase; n=2; Bacteroidetes|Rep:
Dihydrolipoyllysine-residue acetyltransferase -
Pedobacter sp. BAL39
Length = 549
Score = 57.2 bits (132), Expect = 4e-07
Identities = 31/81 (38%), Positives = 43/81 (53%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R D ++ I ++K+ A + KL D G FTI+N G+FG T IINPP
Sbjct: 428 PVVRFADGKSLSHISAEVKDFAQRAKAKKLQPADWEGSTFTISNLGMFGIDEFTAIINPP 487
Query: 438 QSAILGMHAIKDRPMAVNGQV 500
+ IL + I P+ NG V
Sbjct: 488 DACILAIGGISQVPVVKNGAV 508
Score = 42.7 bits (96), Expect = 0.008
Identities = 19/37 (51%), Positives = 25/37 (67%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
+M + LS DHR++DG FL T K LLE+P RLL+
Sbjct: 513 VMKVTLSCDHRVVDGATGSAFLQTFKSLLEEPVRLLV 549
Score = 41.5 bits (93), Expect = 0.019
Identities = 18/51 (35%), Positives = 33/51 (64%)
Frame = +1
Query: 103 IRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLV 255
+++ F +KAV ALK++P VN+S GD + Y+ + ++ +AV+ GL+
Sbjct: 376 VKISFNDMVLKAVAIALKQHPAVNSSWLGDKIRYNEHVNIGVAVAVEDGLL 426
>UniRef50_Q55AS9 Cluster: Pyruvate dehydrogenase complex, component
X; n=2; Dictyostelium discoideum|Rep: Pyruvate
dehydrogenase complex, component X - Dictyostelium
discoideum AX4
Length = 413
Score = 57.2 bits (132), Expect = 4e-07
Identities = 27/68 (39%), Positives = 41/68 (60%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP++ + D + I + K+LA+K DGKL E+ GG F+++N G+FG IIN
Sbjct: 230 TPIITNTDKKQLLAISNESKQLALKARDGKLKPEEFIGGTFSVSNLGMFGITSFNAIINY 289
Query: 435 PQSAILGM 458
PQ+ IL +
Sbjct: 290 PQAGILAI 297
>UniRef50_A7THD4 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 484
Score = 57.2 bits (132), Expect = 4e-07
Identities = 29/77 (37%), Positives = 47/77 (61%), Gaps = 1/77 (1%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSL-MSTPIIN 431
TP++++V++ G+ I ++K+L + KL E+ GG I+N G+ ++ M T IIN
Sbjct: 358 TPIVKNVNSKGLVSISNEVKDLVKRARINKLNPEEFQGGTICISNLGMNNAVSMFTSIIN 417
Query: 432 PPQSAILGMHAIKDRPM 482
PPQSAIL + K P+
Sbjct: 418 PPQSAILAVGTTKRIPV 434
Score = 40.7 bits (91), Expect = 0.033
Identities = 24/78 (30%), Positives = 45/78 (57%), Gaps = 3/78 (3%)
Frame = +1
Query: 31 NEVNMKPIMDLRKQYG-EAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS-IDGDDVV- 201
+++++ ++ LR+ + K + +L VKA+ A+KR PEVN ++ ++V+
Sbjct: 280 SDISVTKLLRLRQSLNNDPANKNNDYKLSINDILVKAISLAVKRVPEVNTCWLEKENVIR 339
Query: 202 YHNYFDVSMAVSTPRGLV 255
DVS+AV+TP GL+
Sbjct: 340 QFENVDVSVAVATPTGLI 357
Score = 33.5 bits (73), Expect = 5.0
Identities = 13/31 (41%), Positives = 22/31 (70%)
Frame = +2
Query: 530 SYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
++DHR IDG + F+ +K ++E+P +LLL
Sbjct: 454 TFDHRTIDGAKGGEFMHALKTIIENPLQLLL 484
>UniRef50_Q5EIH5 Cluster: Dihydrolipoamide succinyltransferase
component E2; n=2; Novosphingobium aromaticivorans|Rep:
Dihydrolipoamide succinyltransferase component E2 -
Sphingomonas aromaticivorans
Length = 406
Score = 56.8 bits (131), Expect = 5e-07
Identities = 29/78 (37%), Positives = 46/78 (58%), Gaps = 1/78 (1%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLM-STPIINP 434
PV+R+ ++L + I LA K G L +D+ GG FTI+N G G ++ + ++NP
Sbjct: 285 PVVRNAESLNARGLTDAIAALADKARAGTLRPQDMEGGTFTISNPGSMGPVVRAEALLNP 344
Query: 435 PQSAILGMHAIKDRPMAV 488
PQ A+LG+ I P+A+
Sbjct: 345 PQVALLGLPGIVRAPVAI 362
Score = 42.7 bits (96), Expect = 0.008
Identities = 19/43 (44%), Positives = 27/43 (62%)
Frame = +2
Query: 479 DGGEWSG*DPPMMYLALSYDHRLIDGRESVGFLVTIKELLEDP 607
DG W+ P++ L+LS+DHR +DG + FL T+K LE P
Sbjct: 364 DGDAWAMAVRPLLRLSLSFDHRALDGGPVIAFLNTLKATLERP 406
>UniRef50_A4XHV3 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Caldicellulosiruptor
saccharolyticus DSM 8903|Rep: Catalytic domain of
components of various dehydrogenase complexes -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494
/ DSM 8903)
Length = 460
Score = 56.8 bits (131), Expect = 5e-07
Identities = 30/81 (37%), Positives = 44/81 (54%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
P + + + + I K+ KEL G + + L G FT+TN G FG TP++NPP
Sbjct: 338 PTIFNSNKKSLNQISKEAKELIQLCRKGTINPDLLKGATFTVTNLGSFGIEGFTPVLNPP 397
Query: 438 QSAILGMHAIKDRPMAVNGQV 500
Q+ ILG++ I R NGQ+
Sbjct: 398 QTGILGVNTIVMRAKEQNGQI 418
Score = 33.5 bits (73), Expect = 5.0
Identities = 15/37 (40%), Positives = 25/37 (67%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLL 619
P + L+L++DHR +DG ++ FL +K+ LE+ LL
Sbjct: 422 PAIGLSLTFDHRALDGADAARFLQDLKKWLENFELLL 458
>UniRef50_A0K281 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Arthrobacter|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Arthrobacter sp. (strain FB24)
Length = 527
Score = 56.4 bits (130), Expect = 6e-07
Identities = 30/93 (32%), Positives = 47/93 (50%), Gaps = 3/93 (3%)
Frame = +3
Query: 231 GFYAARPG---TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVF 401
G AA P P +++ L + ++ + +LA GK ++ GG T+TN G
Sbjct: 394 GIAAATPRGLMVPNIKNAQDLSLKELALALNDLATTARAGKTRPAEMQGGTLTVTNIGAL 453
Query: 402 GSLMSTPIINPPQSAILGMHAIKDRPMAVNGQV 500
G TPIINP + AI+ IK +P ++G+V
Sbjct: 454 GIDTGTPIINPGEVAIVAFGTIKQKPWVLDGEV 486
Score = 33.9 bits (74), Expect = 3.8
Identities = 21/59 (35%), Positives = 33/59 (55%), Gaps = 7/59 (11%)
Frame = +1
Query: 100 GIRLGFMSFYVKAVVEALKRYPEVNA----SIDGDD---VVYHNYFDVSMAVSTPRGLV 255
GI++ + KAV+ A R P VNA S DG D + ++ ++ +A +TPRGL+
Sbjct: 346 GIKVSPLLILAKAVIWAAARNPSVNATWVDSADGSDTAEIHVKHFMNLGIAAATPRGLM 404
Score = 33.9 bits (74), Expect = 3.8
Identities = 15/32 (46%), Positives = 22/32 (68%)
Frame = +2
Query: 530 SYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
S+DHR++DG S F+ + +LE+P LLLD
Sbjct: 497 SFDHRVVDGDLSARFMADVAAILEEPA-LLLD 527
>UniRef50_Q9RXQ3 Cluster: Pyruvate dehydrogenase complex,
dihydrolipoamide acetyltransferase E2 component; n=4;
Deinococci|Rep: Pyruvate dehydrogenase complex,
dihydrolipoamide acetyltransferase E2 component -
Deinococcus radiodurans
Length = 617
Score = 56.0 bits (129), Expect = 8e-07
Identities = 27/82 (32%), Positives = 50/82 (60%), Gaps = 2/82 (2%)
Frame = +1
Query: 16 MLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID--G 189
M+T F++ ++ + + RK++G EK G +L +K V AL+++P+ NAS+D
Sbjct: 412 MVTHFDKADVTAMEETRKRFGARVEKEGG-KLTMTHILMKVVANALRKFPKFNASLDLGA 470
Query: 190 DDVVYHNYFDVSMAVSTPRGLV 255
+ V+Y + ++ +AV TP GL+
Sbjct: 471 EQVIYKEFVNIGVAVDTPVGLL 492
Score = 55.6 bits (128), Expect = 1e-06
Identities = 26/67 (38%), Positives = 41/67 (61%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV++D D G+ ++ + ELA + + KL +++ G FTI+N G G TPI+N P
Sbjct: 494 PVVKDADRKGITELVLDLSELAGRARERKLKPDEMQGATFTISNLGGIGGNAFTPIVNSP 553
Query: 438 QSAILGM 458
+ AILG+
Sbjct: 554 EVAILGV 560
Score = 40.7 bits (91), Expect = 0.033
Identities = 19/32 (59%), Positives = 24/32 (75%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDP 607
M+ L+L+YDHRLIDG ++ FL I E LEDP
Sbjct: 581 MLPLSLTYDHRLIDGADAARFLRYICESLEDP 612
>UniRef50_Q67RX4 Cluster: Putative uncharacterized protein; n=1;
Symbiobacterium thermophilum|Rep: Putative
uncharacterized protein - Symbiobacterium thermophilum
Length = 262
Score = 56.0 bits (129), Expect = 8e-07
Identities = 34/90 (37%), Positives = 46/90 (51%), Gaps = 4/90 (4%)
Frame = +3
Query: 231 GFYAARPG---TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVF 401
G A PG PV+ + +G D+ + I K G L+ +L+G F ITN G +
Sbjct: 130 GIATAVPGGVLLPVVPGAERMGFWDLARAIHLQTQKARAGLLSPHELSGHTFVITNTGRY 189
Query: 402 GS-LMSTPIINPPQSAILGMHAIKDRPMAV 488
G+ L TPII PP IL AI+ RP+ V
Sbjct: 190 GATLFGTPIIQPPNVGILAFEAIQKRPVVV 219
Score = 50.8 bits (116), Expect = 3e-05
Identities = 25/85 (29%), Positives = 46/85 (54%)
Frame = +1
Query: 1 KNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNAS 180
+ +TA +T EV+ ++ +R+ E+ GIRL ++ F+ A V ALK +P +NA
Sbjct: 56 QRTTAPVTVVAEVDATGLISVRESLKPLAERHLGIRLTYLPFFAAATVRALKAWPIMNAM 115
Query: 181 IDGDDVVYHNYFDVSMAVSTPRGLV 255
+ V Y ++ +A + P G++
Sbjct: 116 LTPQGFVIPRYINLGIATAVPGGVL 140
Score = 50.8 bits (116), Expect = 3e-05
Identities = 21/31 (67%), Positives = 25/31 (80%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLE 601
PMMYLAL+ DHR +DG E +GFL T+KE LE
Sbjct: 228 PMMYLALTADHRAVDGAEMIGFLATVKEALE 258
>UniRef50_Q2JGZ2 Cluster: Dehydrogenase subunit; n=1; Frankia sp.
CcI3|Rep: Dehydrogenase subunit - Frankia sp. (strain
CcI3)
Length = 524
Score = 56.0 bits (129), Expect = 8e-07
Identities = 42/141 (29%), Positives = 64/141 (45%), Gaps = 5/141 (3%)
Frame = +3
Query: 99 RHPSGLYVLLRESGG*SPETLPGSERFYRRR*RGLPQL--FRRQHGGFYAARPG---TPV 263
RHP + ++GG PE E G P++ + R + G A P P
Sbjct: 349 RHPMINSSWVEDAGGGRPENGGRPEN------GGRPEIHVYDRVNLGIAVAGPRGLVVPT 402
Query: 264 LRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPPQS 443
+ D L + + + L +L+ DL GG TITN GV G + TPI+NP ++
Sbjct: 403 IPDAGRLDVVGLAHALAGLTTAARADRLSPADLRGGTITITNVGVLGVDIGTPILNPGEA 462
Query: 444 AILGMHAIKDRPMAVNGQVEI 506
AIL + +I+ P GQ+ +
Sbjct: 463 AILALGSIRPMPWVHEGQLTV 483
Score = 33.1 bits (72), Expect = 6.6
Identities = 13/33 (39%), Positives = 21/33 (63%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPT 610
++ LALS+DHR++DG L + ++ DPT
Sbjct: 486 VVQLALSFDHRIVDGALGSAVLADVGAVITDPT 518
>UniRef50_Q57Z16 Cluster: Dihydrolipoamide branched chain
transacylase, putative; n=3; Trypanosoma|Rep:
Dihydrolipoamide branched chain transacylase, putative -
Trypanosoma brucei
Length = 439
Score = 56.0 bits (129), Expect = 8e-07
Identities = 29/91 (31%), Positives = 49/91 (53%), Gaps = 3/91 (3%)
Frame = +3
Query: 216 RRQHGGFYAARPG---TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTIT 386
+ H GF P PV+RDV +A++ ++ EL G ++ + + G FT++
Sbjct: 296 KAHHIGFAMDTPKGLVVPVVRDVQQKSVAELVHEVNELVTLGRKSQIPPDRMKDGTFTLS 355
Query: 387 NGGVFGSLMSTPIINPPQSAILGMHAIKDRP 479
N G G++ +TP++NPPQ AI + I+ P
Sbjct: 356 NIGPIGAIYATPMLNPPQVAIGAIGRIQQLP 386
Score = 39.9 bits (89), Expect = 0.058
Identities = 23/90 (25%), Positives = 43/90 (47%), Gaps = 7/90 (7%)
Frame = +1
Query: 7 STAMLTTFNEVNMKPIMDLRKQYGEAFEK-----RHGIRLGFMSFYVKAVVEALKRYPEV 171
S T +EV + +++ + +A R G ++ M ++KA ++L +YPE+
Sbjct: 222 SVPSFTACDEVEVSQLLNFQHILRDALNSSSEGVRDGSKVSLMPLFIKAASQSLLQYPEL 281
Query: 172 NASIDG--DDVVYHNYFDVSMAVSTPRGLV 255
NA + D + + A+ TP+GLV
Sbjct: 282 NAHVSSECDKLFVKKAHHIGFAMDTPKGLV 311
>UniRef50_Q63HZ8 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex;
n=14; Burkholderia|Rep: Lipoamide acyltransferase
component of branched-chain alpha-keto acid
dehydrogenase complex - Burkholderia pseudomallei
(Pseudomonas pseudomallei)
Length = 483
Score = 55.6 bits (128), Expect = 1e-06
Identities = 28/81 (34%), Positives = 44/81 (54%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R + I ++ LA G+ ++L+G TIT+ G G + STP+IN P
Sbjct: 361 PVVRHAEARDPWSIAAEVARLADAARAGRAERDELSGSTITITSLGALGGIASTPVINSP 420
Query: 438 QSAILGMHAIKDRPMAVNGQV 500
+ I+G++ I +RPM G V
Sbjct: 421 EVGIVGVNRIVERPMFRGGAV 441
Score = 38.3 bits (85), Expect = 0.18
Identities = 15/38 (39%), Positives = 26/38 (68%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLD 625
+M L+ S+DHR+IDG ++ F+ ++ LLE P L ++
Sbjct: 446 LMNLSSSFDHRVIDGMDAAEFIQAVRGLLEQPALLFVE 483
>UniRef50_Q5P915 Cluster: Pyruvate dehydrogenase multienzyme
complex, dihydrolipoamide acetyltransferase component;
n=16; Proteobacteria|Rep: Pyruvate dehydrogenase
multienzyme complex, dihydrolipoamide acetyltransferase
component - Azoarcus sp. (strain EbN1) (Aromatoleum
aromaticum (strain EbN1))
Length = 583
Score = 55.2 bits (127), Expect = 1e-06
Identities = 28/75 (37%), Positives = 44/75 (58%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+++ D + +I + ELA K DGKL D++G FTI++ G G PI+N P
Sbjct: 462 PVIKNADRKSVFEIAAESGELAKKARDGKLGPADMSGACFTISSLGGIGGTYFAPIVNAP 521
Query: 438 QSAILGMHAIKDRPM 482
+ AILG++ +P+
Sbjct: 522 EVAILGVNKSAMKPI 536
Score = 50.4 bits (115), Expect = 4e-05
Identities = 23/59 (38%), Positives = 37/59 (62%), Gaps = 4/59 (6%)
Frame = +1
Query: 91 KRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGD----DVVYHNYFDVSMAVSTPRGLV 255
++ G +L ++F +KA V AL+++PE N S+D +VY YF+++ A TP GLV
Sbjct: 402 EKSGKKLTMLAFIIKASVRALQQFPEFNTSLDASGGEMSLVYKKYFNIAFAADTPNGLV 460
>UniRef50_Q23VX7 Cluster: 2-oxo acid dehydrogenases acyltransferase;
n=1; Tetrahymena thermophila SB210|Rep: 2-oxo acid
dehydrogenases acyltransferase - Tetrahymena thermophila
SB210
Length = 462
Score = 55.2 bits (127), Expect = 1e-06
Identities = 27/82 (32%), Positives = 46/82 (56%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
P +++V L + DI+K+IK L +G G L +DL G+ I+N G G + P+I P
Sbjct: 329 PNIKNVQNLSILDIQKEIKRLVKEGEAGTLGPKDLFDGSICISNIGTIGGTYTGPLIFAP 388
Query: 438 QSAILGMHAIKDRPMAVNGQVE 503
Q+ I+G+ + P +N ++
Sbjct: 389 QTTIVGLGRVMTLPRYINKSLD 410
Score = 39.1 bits (87), Expect = 0.10
Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 11/91 (12%)
Frame = +1
Query: 16 MLTTFNEVNMKPIMDLRKQYG--------EAFEKRHGIRLGFMSFYVKAVVEALKRYPEV 171
M + E N P + L+ +Y E +K + FM+F++KA ALK YP +
Sbjct: 237 MQKSMTEANTIPHLYLKDEYDLTNLTVLREQIKKSQNQSITFMTFFIKAFSLALKEYPIL 296
Query: 172 NASIDGD---DVVYHNYFDVSMAVSTPRGLV 255
N+ D + + ++S+AV +P+GLV
Sbjct: 297 NSLYDVNKPFEYTLVQNHNISLAVDSPKGLV 327
>UniRef50_Q9M724 Cluster: Branched chain alpha-keto acid
dehydrogenase E2 subunit; n=9; Magnoliophyta|Rep:
Branched chain alpha-keto acid dehydrogenase E2 subunit
- Arabidopsis thaliana (Mouse-ear cress)
Length = 483
Score = 54.8 bits (126), Expect = 2e-06
Identities = 24/74 (32%), Positives = 43/74 (58%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
P +++V +L + +I K++ L + KL ED+TGG T++N G G +P++N P
Sbjct: 358 PNIKNVQSLSLLEITKELSRLQHLAANNKLNPEDVTGGTITLSNIGAIGGKFGSPLLNLP 417
Query: 438 QSAILGMHAIKDRP 479
+ AI+ + I+ P
Sbjct: 418 EVAIIALGRIEKVP 431
Score = 33.5 bits (73), Expect = 5.0
Identities = 19/76 (25%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Frame = +1
Query: 34 EVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGD--DVVYH 207
E+N +++L KQ+ + I+ F+ +K++ AL +YP VN+ + + +++
Sbjct: 282 EINCDSLVEL-KQFFKENNTDSTIKHTFLPTLIKSLSMALTKYPFVNSCFNAESLEIILK 340
Query: 208 NYFDVSMAVSTPRGLV 255
++ +A++T GLV
Sbjct: 341 GSHNIGVAMATEHGLV 356
>UniRef50_Q9VXY3 Cluster: CG5599-PA; n=4; Diptera|Rep: CG5599-PA -
Drosophila melanogaster (Fruit fly)
Length = 462
Score = 54.8 bits (126), Expect = 2e-06
Identities = 29/78 (37%), Positives = 49/78 (62%), Gaps = 3/78 (3%)
Frame = +1
Query: 31 NEVNMKPIMDLRKQYGEAFEKRHGI-RLGFMSFYVKAVVEALKRYPEVNASID--GDDVV 201
+E++M +M R Q + K +G+ +L FM F +KA AL +YP VN+S+D + +V
Sbjct: 261 DEIDMTQLMQFRNQL-QLVAKENGVPKLTFMPFCIKAASIALSKYPIVNSSLDLASESLV 319
Query: 202 YHNYFDVSMAVSTPRGLV 255
+ ++S+A+ TP+GLV
Sbjct: 320 FKGAHNISVAIDTPQGLV 337
>UniRef50_Q0WQF7 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component 1 of pyruvate dehydrogenase
complex, mitochondrial precursor; n=4;
Magnoliophyta|Rep: Dihydrolipoyllysine-residue
acetyltransferase component 1 of pyruvate dehydrogenase
complex, mitochondrial precursor - Arabidopsis thaliana
(Mouse-ear cress)
Length = 637
Score = 54.8 bits (126), Expect = 2e-06
Identities = 26/68 (38%), Positives = 41/68 (60%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP++++ D ++ I ++KELA K GKL + GG F+I+N G++ IINP
Sbjct: 510 TPIIKNADQKSISAISLEVKELAQKARSGKLAPHEFQGGTFSISNLGMYPVDNFCAIINP 569
Query: 435 PQSAILGM 458
PQ+ IL +
Sbjct: 570 PQAGILAV 577
Score = 43.6 bits (98), Expect = 0.005
Identities = 23/77 (29%), Positives = 45/77 (58%), Gaps = 2/77 (2%)
Frame = +1
Query: 31 NEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGD--DVVY 204
++V + P++ RK+ ++ HG+++ +KAV AL+ + NA D + D+V
Sbjct: 437 SDVVLDPLLAFRKE----LQENHGVKVSVNDIVIKAVAVALRNVRQANAFWDAEKGDIVM 492
Query: 205 HNYFDVSMAVSTPRGLV 255
+ D+S+AV+T +GL+
Sbjct: 493 CDSVDISIAVATEKGLM 509
Score = 33.5 bits (73), Expect = 5.0
Identities = 15/36 (41%), Positives = 21/36 (58%)
Frame = +2
Query: 515 MYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
M + LS DHR+ DG+ F+ ++ ED RLLL
Sbjct: 602 MNVTLSADHRIFDGQVGASFMSELRSNFEDVRRLLL 637
>UniRef50_P12695 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=3;
Saccharomycetales|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 482
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/73 (36%), Positives = 44/73 (60%), Gaps = 1/73 (1%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSL-MSTPIIN 431
TP++++ + G++ I +IKEL + KL E+ GG I+N G+ ++ M T IIN
Sbjct: 356 TPIVKNCEAKGLSQISNEIKELVKRARINKLAPEEFQGGTICISNMGMNNAVNMFTSIIN 415
Query: 432 PPQSAILGMHAIK 470
PPQS IL + ++
Sbjct: 416 PPQSTILAIATVE 428
Score = 36.3 bits (80), Expect = 0.71
Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Frame = +1
Query: 31 NEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHN 210
+++++ ++ LR+ ++ +L VKA+ A KR P+ NA ++ V
Sbjct: 281 SKISISKLLKLRQSLNATANDKY--KLSINDLLVKAITVAAKRVPDANAYWLPNENVIRK 338
Query: 211 Y--FDVSMAVSTPRGLV 255
+ DVS+AV+TP GL+
Sbjct: 339 FKNVDVSVAVATPTGLL 355
Score = 33.1 bits (72), Expect = 6.6
Identities = 12/31 (38%), Positives = 21/31 (67%)
Frame = +2
Query: 530 SYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
++DHR IDG + F+ +K ++E+P +LL
Sbjct: 452 TFDHRTIDGAKGAEFMKELKTVIENPLEMLL 482
>UniRef50_P11182 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex,
mitochondrial precursor (EC 2.3.1.168)
(Dihydrolipoyllysine-residue
(2-methylpropanoyl)transferase); n=29; Eumetazoa|Rep:
Lipoamide acyltransferase component of branched-chain
alpha-keto acid dehydrogenase complex, mitochondrial
precursor (EC 2.3.1.168) (Dihydrolipoyllysine-residue
(2-methylpropanoyl)transferase) - Homo sapiens (Human)
Length = 482
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/74 (36%), Positives = 42/74 (56%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
P +++V + DI ++ L G G+L+ DLTGG FT++N G G + P+I PP
Sbjct: 357 PNVKNVQICSIFDIATELNRLQKLGSVGQLSTTDLTGGTFTLSNIGSIGGTFAKPVIMPP 416
Query: 438 QSAILGMHAIKDRP 479
+ AI + +IK P
Sbjct: 417 EVAIGALGSIKAIP 430
Score = 44.4 bits (100), Expect = 0.003
Identities = 23/77 (29%), Positives = 47/77 (61%), Gaps = 2/77 (2%)
Frame = +1
Query: 31 NEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGD--DVVY 204
+E+++ ++ LR++ R GI+L FM F++KA L ++P +NAS+D + ++ Y
Sbjct: 280 DEIDLTELVKLREELKPIAFAR-GIKLSFMPFFLKAASLGLLQFPILNASVDENCQNITY 338
Query: 205 HNYFDVSMAVSTPRGLV 255
++ +A+ T +GL+
Sbjct: 339 KASHNIGIAMDTEQGLI 355
>UniRef50_A0Z3Y6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dihydrolipoamide acyltransferase (E2)
component, and related enzyme; n=1; marine gamma
proteobacterium HTCC2080|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide acyltransferase
(E2) component, and related enzyme - marine gamma
proteobacterium HTCC2080
Length = 388
Score = 54.4 bits (125), Expect = 3e-06
Identities = 27/78 (34%), Positives = 44/78 (56%)
Frame = +3
Query: 273 VDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPPQSAIL 452
V+ A++ + LA K LT ED++GG+FT++N G++G T IINPP AIL
Sbjct: 277 VEAKSPAEVAQATGALAEKARSNSLTKEDISGGSFTVSNLGMYGISEFTAIINPPMGAIL 336
Query: 453 GMHAIKDRPMAVNGQVEI 506
+ + + + +G+ I
Sbjct: 337 ALGKAEPKVVVKDGEQSI 354
>UniRef50_Q4WQ92 Cluster: 2-oxo acid dehydrogenases acyltransferase,
putative; n=1; Aspergillus fumigatus|Rep: 2-oxo acid
dehydrogenases acyltransferase, putative - Aspergillus
fumigatus (Sartorya fumigata)
Length = 460
Score = 54.4 bits (125), Expect = 3e-06
Identities = 28/75 (37%), Positives = 43/75 (57%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
P ++DV + +I +IK L+ G +GKLT DL+GG T++N G G P+I P
Sbjct: 335 PNIKDVANRTIMEIAAEIKRLSALGKEGKLTPADLSGGTITVSNIGNIGGTYVGPVIVPT 394
Query: 438 QSAILGMHAIKDRPM 482
+ AILG+ + P+
Sbjct: 395 EVAILGVGKSRTVPV 409
Score = 37.1 bits (82), Expect = 0.41
Identities = 23/80 (28%), Positives = 43/80 (53%), Gaps = 5/80 (6%)
Frame = +1
Query: 31 NEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID-----GDD 195
+E+ + I LRK+ A + + ++ F+ F +KAV AL YP +NA +D
Sbjct: 256 DELKINDITALRKKL--ASDPKDPKKVTFLPFVIKAVSLALNEYPLLNAKVDLSIPEKPK 313
Query: 196 VVYHNYFDVSMAVSTPRGLV 255
++ ++ +A+ TP+GL+
Sbjct: 314 LIMRPKHNIGVALDTPQGLI 333
>UniRef50_Q9PJZ6 Cluster: 2-oxo acid dehydrogenase, E2 component,
lipoamide acyltransferase; n=9; Chlamydiaceae|Rep: 2-oxo
acid dehydrogenase, E2 component, lipoamide
acyltransferase - Chlamydia muridarum
Length = 410
Score = 54.0 bits (124), Expect = 3e-06
Identities = 26/73 (35%), Positives = 42/73 (57%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+ + G+ I K + +L+ + KL + GG+ T+TN G+ G+L+ PII P
Sbjct: 290 PVIHNCQDRGLVSIAKALADLSSRARASKLDASEAKGGSVTLTNFGMTGALIGMPIIRYP 349
Query: 438 QSAILGMHAIKDR 476
+ AILG+ I+ R
Sbjct: 350 EVAILGIGTIQKR 362
Score = 49.2 bits (112), Expect = 9e-05
Identities = 21/68 (30%), Positives = 42/68 (61%)
Frame = +1
Query: 34 EVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNY 213
+V++ +M+L E F HG++L SF ++ + ++L+++P +N S+DGD +V
Sbjct: 214 DVDVTDLMNLISLERERFAAAHGVKLTITSFIIQCLAKSLEQFPLLNGSLDGDTIVLKKA 273
Query: 214 FDVSMAVS 237
+V +AV+
Sbjct: 274 VNVGVAVN 281
Score = 35.1 bits (77), Expect = 1.6
Identities = 15/33 (45%), Positives = 21/33 (63%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPT 610
MMY+ L++DHR++DG FL +K LE T
Sbjct: 376 MMYVTLTFDHRVLDGIYGGEFLTALKNRLESVT 408
>UniRef50_A5UU13 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=4; Bacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Roseiflexus sp. RS-1
Length = 459
Score = 54.0 bits (124), Expect = 3e-06
Identities = 27/84 (32%), Positives = 46/84 (54%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+ + + I ++ K + +GK+T + L GG FT++N G++G T II PP
Sbjct: 335 PVVANCQDRSLGSIARETKRIVALAREGKITPDLLQGGTFTVSNLGMYGIPEFTSIITPP 394
Query: 438 QSAILGMHAIKDRPMAVNGQVEIL 509
Q+A L + AI+ P + E++
Sbjct: 395 QAASLAVGAIRRTPAFKDDSDEVV 418
Score = 39.5 bits (88), Expect = 0.076
Identities = 19/37 (51%), Positives = 23/37 (62%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
+M L LS DHR+ DG E FL +K LLE P LL+
Sbjct: 422 LMMLTLSADHRVTDGAEVARFLNDVKRLLEQPLALLV 458
Score = 37.1 bits (82), Expect = 0.41
Identities = 23/74 (31%), Positives = 37/74 (50%)
Frame = +1
Query: 34 EVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNY 213
EV+M + LR Q + I + M VKA AL +P +NAS D ++ H
Sbjct: 262 EVDMGAALALRAQANAGRPREDQISVNDM--VVKACAVALLAFPNLNASYSDDGIILHPT 319
Query: 214 FDVSMAVSTPRGLV 255
++++AV+ GL+
Sbjct: 320 VNIAIAVALESGLM 333
>UniRef50_A5CVP1 Cluster: Pyruvate dehydrogenase complex E2
component; n=3; Bacteria|Rep: Pyruvate dehydrogenase
complex E2 component - Vesicomyosocius okutanii subsp.
Calyptogena okutanii (strain HA)
Length = 507
Score = 54.0 bits (124), Expect = 3e-06
Identities = 28/81 (34%), Positives = 52/81 (64%), Gaps = 2/81 (2%)
Frame = +1
Query: 19 LTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID--GD 192
+T F+EVN+ + R++ +K +GI+L + F +KA+V LK + NAS+D G+
Sbjct: 311 VTQFDEVNINQMEAYRQE-----QKANGIKLTPLVFIMKALVRTLKNHLRFNASLDESGE 365
Query: 193 DVVYHNYFDVSMAVSTPRGLV 255
+++ YF++ +A+ TP+GL+
Sbjct: 366 NLIIKKYFNLGIAMDTPKGLI 386
Score = 54.0 bits (124), Expect = 3e-06
Identities = 25/67 (37%), Positives = 39/67 (58%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+RDV+ + D+ K++ E + + KL D+ G TI++ G G TPI+N P
Sbjct: 388 PVIRDVEKKSLTDLAKELFETSKNARENKLKPADMQGSGLTISSLGGIGGTQFTPIVNAP 447
Query: 438 QSAILGM 458
+ AILG+
Sbjct: 448 EVAILGI 454
>UniRef50_A1T0M1 Cluster: Pyruvate dehydrogenase complex, E2
component dihydrolipoamide acetyltransferase; n=1;
Psychromonas ingrahamii 37|Rep: Pyruvate dehydrogenase
complex, E2 component dihydrolipoamide acetyltransferase
- Psychromonas ingrahamii (strain 37)
Length = 451
Score = 54.0 bits (124), Expect = 3e-06
Identities = 27/83 (32%), Positives = 47/83 (56%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+R TL + + +++K+ + L +L+GG+FT+T+ G G+ +I PP
Sbjct: 329 PVIRAAQTLSPSKMMERLKQQVTHARNDSLVFSELSGGSFTVTSIGERGAEQMFAVIFPP 388
Query: 438 QSAILGMHAIKDRPMAVNGQVEI 506
Q AIL + + MAV+G ++I
Sbjct: 389 QVAILALGSPHQEVMAVDGSIKI 411
>UniRef50_A0PU60 Cluster: Dihydrolipoamide S-acetyltransferase E2
component PdhC; n=3; Mycobacterium|Rep: Dihydrolipoamide
S-acetyltransferase E2 component PdhC - Mycobacterium
ulcerans (strain Agy99)
Length = 389
Score = 54.0 bits (124), Expect = 3e-06
Identities = 30/85 (35%), Positives = 44/85 (51%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV+ D + ++ + EL +G L L G FT++N G G P+IN P
Sbjct: 266 PVIADAHRMTTRELVCRAAELITGAREGTLAPGQLRGWTFTVSNYGALGVDDGVPVINHP 325
Query: 438 QSAILGMHAIKDRPMAVNGQVEILR 512
+AILGM +IK RP+ V G ++R
Sbjct: 326 DAAILGMGSIKPRPV-VRGDEVVVR 349
Score = 35.1 bits (77), Expect = 1.6
Identities = 15/40 (37%), Positives = 23/40 (57%)
Frame = +2
Query: 509 PMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV 628
P M L +DHR+ DG + F+ ++ L+E P LLD+
Sbjct: 350 PTMSLTCVFDHRVADGAQVARFICELRGLIEAPETALLDL 389
>UniRef50_Q6FDE9 Cluster: Dihydrolipoamide acetyltransferase; n=3;
Gammaproteobacteria|Rep: Dihydrolipoamide
acetyltransferase - Acinetobacter sp. (strain ADP1)
Length = 513
Score = 53.6 bits (123), Expect = 4e-06
Identities = 24/68 (35%), Positives = 41/68 (60%)
Frame = +3
Query: 255 TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINP 434
TP+++ + +A I +++LA + GKL ++ GG+F+I+N G+ G IINP
Sbjct: 391 TPIVKAANQKSLATISSTMRDLATRAKTGKLQPDEFQGGSFSISNLGMLGIKNFDAIINP 450
Query: 435 PQSAILGM 458
PQ AI+ +
Sbjct: 451 PQGAIMAL 458
Score = 37.1 bits (82), Expect = 0.41
Identities = 16/37 (43%), Positives = 24/37 (64%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
MM + LS DHR+IDG FL + K+ +E+P +L+
Sbjct: 477 MMTVTLSCDHRVIDGALGAKFLASFKQFVENPALILV 513
Score = 36.7 bits (81), Expect = 0.54
Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 2/76 (2%)
Frame = +1
Query: 34 EVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASID--GDDVVYH 207
EVN++ + LR+Q + + ++L +KA AL + PEVN D ++
Sbjct: 318 EVNVEALQALRQQINDTVPQ---LKLSINDMLIKAAAAALIKVPEVNVQYDEQKQQILQF 374
Query: 208 NYFDVSMAVSTPRGLV 255
D+S+AV+ GL+
Sbjct: 375 KDADISVAVAIENGLI 390
>UniRef50_Q4E6V7 Cluster: Putative uncharacterized protein; n=1;
Wolbachia endosymbiont of Drosophila simulans|Rep:
Putative uncharacterized protein - Wolbachia
endosymbiont of Drosophila simulans
Length = 173
Score = 53.6 bits (123), Expect = 4e-06
Identities = 31/60 (51%), Positives = 36/60 (60%)
Frame = -3
Query: 182 IEAFTSG*RFRASTTAFT*KDIKPRRMPWRFSNASPYCLRRSIIGFMLTSLNVVSMAVEF 3
I A SG F A T AF DIKP +P+ FS AS Y + RS+ FM SLNVVS+A F
Sbjct: 7 ISALISGISFSACTAAFIKNDIKPSFIPYFFSKASLYFVLRSMTFFMSISLNVVSIAAVF 66
>UniRef50_Q59638 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=7; Proteobacteria|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Pseudomonas
aeruginosa
Length = 547
Score = 53.6 bits (123), Expect = 4e-06
Identities = 31/89 (34%), Positives = 47/89 (52%), Gaps = 3/89 (3%)
Frame = +3
Query: 225 HGGFYAARPG---TPVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGG 395
H GF P PV+RDVD + + + +LA K + KL+ + + G FTI++ G
Sbjct: 412 HIGFAVDTPDGLLVPVIRDVDRKSLLQLAAEAADLADKARNKKLSADAMQGACFTISSLG 471
Query: 396 VFGSLMSTPIINPPQSAILGMHAIKDRPM 482
G TPI+N P+ AILG+ +P+
Sbjct: 472 HIGGTGFTPIVNAPEVAILGVSKATMQPV 500
Score = 35.9 bits (79), Expect = 0.94
Identities = 18/37 (48%), Positives = 24/37 (64%)
Frame = +2
Query: 512 MMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 622
M+ L+LSYDHR+I+G + F + ELL D LLL
Sbjct: 511 MLPLSLSYDHRVINGAAAARFTKRLGELLADIRTLLL 547
>UniRef50_Q1LSX2 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=1;
Baumannia cicadellinicola str. Hc (Homalodisca
coagulata)|Rep: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Baumannia cicadellinicola subsp. Homalodisca coagulata
Length = 358
Score = 53.2 bits (122), Expect = 6e-06
Identities = 28/75 (37%), Positives = 42/75 (56%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PV +V+ G+ + +++ LA K GKL D+ FTI+N G G + TPIIN P
Sbjct: 237 PVCHNVNKKGIITLSQEVINLAQKAHTGKLIPSDMQDSCFTISNLGNIGGMHFTPIINAP 296
Query: 438 QSAILGMHAIKDRPM 482
+ AILG+ +P+
Sbjct: 297 EVAILGVSKTYFKPV 311
>UniRef50_Q13GQ6 Cluster: Dihydrolipoamide acyltransferase (E2)
component of 2-oxoacid dehydrogenase complexes; n=1;
Burkholderia xenovorans LB400|Rep: Dihydrolipoamide
acyltransferase (E2) component of 2-oxoacid
dehydrogenase complexes - Burkholderia xenovorans
(strain LB400)
Length = 428
Score = 53.2 bits (122), Expect = 6e-06
Identities = 29/82 (35%), Positives = 46/82 (56%), Gaps = 2/82 (2%)
Frame = +3
Query: 258 PVLRDVDTLGMADIEKKIKELAVKGCDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPP 437
PVLRDV + ++ + E + G+L ++ GG T++N G+ + T IINP
Sbjct: 305 PVLRDVGRQALGEVARHASEAIGRAQAGQLNAAEMAGGAITVSNAGMHDVTLMTSIINPG 364
Query: 438 QSAILGMHAIKD--RPMAVNGQ 497
QS ILG+ +++ RP A +GQ
Sbjct: 365 QSMILGVGSVRQVFRPDA-HGQ 385
Score = 34.7 bits (76), Expect = 2.2
Identities = 25/74 (33%), Positives = 31/74 (41%)
Frame = +1
Query: 34 EVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNY 213
E + + LR Q +A R R F V AV AL PE N D +
Sbjct: 233 EAEISAVQRLRSQLNDAQSNR---RFTVNHFVVAAVGRALALVPEANRVWDDSGITSFAA 289
Query: 214 FDVSMAVSTPRGLV 255
DV +AV T RGL+
Sbjct: 290 TDVGVAVHTERGLL 303
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 747,607,291
Number of Sequences: 1657284
Number of extensions: 16443014
Number of successful extensions: 52355
Number of sequences better than 10.0: 341
Number of HSP's better than 10.0 without gapping: 48860
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 52252
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 54545459628
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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