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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= e40h0372
         (762 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI00015B404E Cluster: PREDICTED: similar to ENSANGP000...   165   8e-40
UniRef50_O60256 Cluster: Phosphoribosyl pyrophosphate synthetase...   146   7e-34
UniRef50_A2AAG9 Cluster: Likely ortholog of H. sapiens phosphori...   130   3e-29
UniRef50_Q9VT33 Cluster: Ribose-phosphate pyrophosphokinase; n=4...    94   4e-18
UniRef50_Q16GA3 Cluster: Ribose-phosphate pyrophosphokinase 1, p...    91   4e-17
UniRef50_A7M6E2 Cluster: Ribose-phosphate pyrophosphokinase I; n...    90   6e-17
UniRef50_Q0U4M1 Cluster: Ribose-phosphate pyrophosphokinase; n=1...    90   6e-17
UniRef50_A7TNR7 Cluster: Putative uncharacterized protein; n=1; ...    90   6e-17
UniRef50_Q5A4X7 Cluster: Ribose-phosphate pyrophosphokinase; n=1...    89   8e-17
UniRef50_P32895 Cluster: Ribose-phosphate pyrophosphokinase 1; n...    89   1e-16
UniRef50_Q5KCA3 Cluster: Ribose-phosphate pyrophosphokinase; n=1...    89   1e-16
UniRef50_P60891 Cluster: Ribose-phosphate pyrophosphokinase 1; n...    89   1e-16
UniRef50_UPI000156094F Cluster: PREDICTED: similar to PRPS2 prot...    87   4e-16
UniRef50_Q1DW45 Cluster: Ribose-phosphate pyrophosphokinase; n=1...    85   1e-15
UniRef50_A7EV32 Cluster: Putative uncharacterized protein; n=1; ...    85   1e-15
UniRef50_Q4P1D3 Cluster: Ribose-phosphate pyrophosphokinase; n=1...    83   7e-15
UniRef50_A1CDQ3 Cluster: Ribose-phosphate pyrophosphokinase; n=5...    83   1e-14
UniRef50_A3LVW1 Cluster: Ribose-phosphate pyrophosphokinase; n=3...    81   2e-14
UniRef50_Q8X022 Cluster: Ribose-phosphate pyrophosphokinase; n=2...    81   3e-14
UniRef50_Q4P9A7 Cluster: Ribose-phosphate pyrophosphokinase; n=1...    81   4e-14
UniRef50_A6R925 Cluster: Ribose-phosphate pyrophosphokinase I; n...    80   7e-14
UniRef50_Q6CG51 Cluster: Ribose-phosphate pyrophosphokinase; n=1...    78   2e-13
UniRef50_Q12265 Cluster: Probable ribose-phosphate pyrophosphoki...    78   2e-13
UniRef50_Q1AXL6 Cluster: Ribose-phosphate pyrophosphokinase; n=3...    75   2e-12
UniRef50_A5DKD0 Cluster: Ribose-phosphate pyrophosphokinase; n=2...    73   6e-12
UniRef50_P65239 Cluster: Ribose-phosphate pyrophosphokinase 1; n...    71   2e-11
UniRef50_A5V1W5 Cluster: Ribose-phosphate pyrophosphokinase; n=5...    71   3e-11
UniRef50_A0CY99 Cluster: Chromosome undetermined scaffold_31, wh...    71   4e-11
UniRef50_A4VV92 Cluster: Ribose-phosphate pyrophosphokinase; n=3...    70   5e-11
UniRef50_Q8R753 Cluster: Ribose-phosphate pyrophosphokinase; n=1...    70   5e-11
UniRef50_Q6MW31 Cluster: Related to ribose-phosphate pyrophospho...    70   7e-11
UniRef50_Q7MT83 Cluster: Ribose-phosphate pyrophosphokinase; n=2...    70   7e-11
UniRef50_Q88Z84 Cluster: Ribose-phosphate pyrophosphokinase 1; n...    70   7e-11
UniRef50_Q6Z2L5-2 Cluster: Isoform 2 of Q6Z2L5 ; n=1; Oryza sati...    69   1e-10
UniRef50_UPI00006CD8E2 Cluster: ribose-phosphate pyrophosphokina...    69   2e-10
UniRef50_A4T068 Cluster: Ribose-phosphate pyrophosphokinase; n=2...    68   3e-10
UniRef50_Q9U465 Cluster: Phosphoribosylpyrophosphate synthetase;...    67   4e-10
UniRef50_Q42581 Cluster: Ribose-phosphate pyrophosphokinase 1; n...    67   4e-10
UniRef50_A5URX1 Cluster: Ribose-phosphate pyrophosphokinase; n=3...    67   5e-10
UniRef50_A3ZLP4 Cluster: Ribose-phosphate pyrophosphokinase; n=3...    66   7e-10
UniRef50_Q8G5P2 Cluster: Ribose-phosphate pyrophosphokinase; n=5...    66   7e-10
UniRef50_Q8D2K5 Cluster: PrsA protein; n=1; Wigglesworthia gloss...    66   9e-10
UniRef50_Q8IE40 Cluster: Ribose-phosphate pyrophosphokinase, put...    66   9e-10
UniRef50_Q3M5L4 Cluster: Ribose-phosphate pyrophosphokinase; n=1...    65   2e-09
UniRef50_A4EBQ1 Cluster: Putative uncharacterized protein; n=1; ...    65   2e-09
UniRef50_Q6MAT0 Cluster: Probable phosphoribosyl pyrophosphate s...    65   2e-09
UniRef50_Q4XQD5 Cluster: Ribose-phosphate pyrophosphokinase, put...    65   2e-09
UniRef50_Q83GR1 Cluster: Ribose-phosphate pyrophosphokinase; n=3...    64   4e-09
UniRef50_Q6F241 Cluster: Ribose-phosphate pyrophosphokinase; n=6...    64   4e-09
UniRef50_Q9RUD2 Cluster: Probable ribose-phosphate pyrophosphoki...    64   5e-09
UniRef50_A0VM43 Cluster: Ribose-phosphate pyrophosphokinase; n=2...    63   6e-09
UniRef50_Q075L4 Cluster: Plastid ribose-phosphate diphosphokinas...    63   6e-09
UniRef50_Q75JN8 Cluster: Similar to ribose-phosphate pyrophospho...    63   6e-09
UniRef50_Q1GEV9 Cluster: Ribose-phosphate pyrophosphokinase; n=1...    61   3e-08
UniRef50_UPI00005A2C8C Cluster: PREDICTED: similar to Ribose-pho...    61   3e-08
UniRef50_Q4Q3Z4 Cluster: Phosphoribosylpyrophosphate synthetase,...    60   8e-08
UniRef50_Q89DJ1 Cluster: Ribose-phosphate pyrophosphokinase; n=3...    60   8e-08
UniRef50_Q8Y9L8 Cluster: Ribose-phosphate pyrophosphokinase 2; n...    60   8e-08
UniRef50_Q03YB5 Cluster: Ribose-phosphate pyrophosphokinase; n=2...    59   1e-07
UniRef50_P75044 Cluster: Ribose-phosphate pyrophosphokinase; n=6...    59   1e-07
UniRef50_UPI0000EB04C8 Cluster: UPI0000EB04C8 related cluster; n...    58   2e-07
UniRef50_Q822W0 Cluster: Ribose-phosphate pyrophosphokinase; n=2...    58   2e-07
UniRef50_Q74LT0 Cluster: Phosphoribosylpyrophosphate synthetase;...    58   2e-07
UniRef50_Q4Q0M2 Cluster: Phosphoribosylpyrophosphate synthetase,...    58   3e-07
UniRef50_A0E424 Cluster: Chromosome undetermined scaffold_77, wh...    56   7e-07
UniRef50_Q0G092 Cluster: Ribose-phosphate pyrophosphokinase; n=1...    55   2e-06
UniRef50_A7HHV4 Cluster: Ribose-phosphate pyrophosphokinase; n=3...    55   2e-06
UniRef50_Q9PQV0 Cluster: Ribose-phosphate pyrophosphokinase; n=1...    55   2e-06
UniRef50_Q5GTH9 Cluster: Phosphoribosylpyrophosphate synthetase;...    54   4e-06
UniRef50_Q8EUI1 Cluster: Ribose-phosphate pyrophosphokinase; n=1...    53   7e-06
UniRef50_Q4UNC9 Cluster: Ribose-phosphate pyrophosphokinase; n=9...    53   9e-06
UniRef50_Q2GIZ1 Cluster: Ribose-phosphate pyrophosphokinase; n=6...    52   2e-05
UniRef50_Q98R83 Cluster: Ribose-phosphate pyrophosphokinase; n=1...    51   4e-05
UniRef50_Q4QI56 Cluster: Phosphoribosylpyrophosphate synthetase;...    50   8e-05
UniRef50_A7ARJ1 Cluster: Ribose-phosphate pyrophosphokinase, put...    50   8e-05
UniRef50_Q9EWS0 Cluster: Putative ribose-phosphate pyrophosphoki...    46   0.001
UniRef50_Q4DSS9 Cluster: Ribose-phosphate pyrophosphokinase, put...    44   0.003
UniRef50_UPI00015BACA3 Cluster: ribose-phosphate pyrophosphokina...    44   0.004
UniRef50_A2X0F3 Cluster: Ribose-phosphate pyrophosphokinase; n=2...    44   0.004
UniRef50_O62580 Cluster: Phosphoribosyl pyrophosphate synthetase...    43   0.007
UniRef50_Q660Y0 Cluster: Phosphoribosyl pyrophosphate synthetase...    43   0.010
UniRef50_Q0U4M2 Cluster: Putative uncharacterized protein; n=1; ...    43   0.010
UniRef50_Q8KKS6 Cluster: Ribose-phosphate pyrophosphokinase prot...    42   0.022
UniRef50_A4CGY8 Cluster: Phosphoribosylpyrophosphate synthetase;...    41   0.029
UniRef50_Q97Z86 Cluster: Ribose-phosphate pyrophosphokinase; n=5...    41   0.038
UniRef50_A2XQT7 Cluster: Putative uncharacterized protein; n=1; ...    40   0.067
UniRef50_Q4QIB8 Cluster: Ribose-phosphate pyrophosphokinase, put...    39   0.16 
UniRef50_Q3YQZ8 Cluster: Ribose-phosphate pyrophospho kinase; n=...    38   0.27 
UniRef50_A4BQ39 Cluster: Ribose-phosphate pyrophosphokinase; n=9...    38   0.27 
UniRef50_O26877 Cluster: Ribose-phosphate pyrophosphokinase; n=3...    38   0.27 
UniRef50_O83317 Cluster: Phosphoribosyl pyrophosphate synthetase...    38   0.36 
UniRef50_Q0W4S8 Cluster: Ribose-phosphate pyrophosphokinase; n=1...    38   0.36 
UniRef50_Q2GCV8 Cluster: Ribose-phosphate pyrophosphokinase; n=1...    36   0.83 
UniRef50_A4WYL1 Cluster: Putative uncharacterized protein; n=1; ...    36   0.83 
UniRef50_Q8ZU24 Cluster: Ribose-phosphate pyrophosphokinase; n=4...    36   1.4  
UniRef50_Q9F9G7 Cluster: Cwp66; n=19; Clostridium difficile|Rep:...    34   4.4  
UniRef50_A1HDW3 Cluster: Ribose-phosphate diphosphokinase; n=3; ...    33   7.7  
UniRef50_Q8TUT6 Cluster: Ribose-phosphate pyrophosphokinase; n=1...    33   7.7  

>UniRef50_UPI00015B404E Cluster: PREDICTED: similar to
           ENSANGP00000018618; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to ENSANGP00000018618 - Nasonia
           vitripennis
          Length = 322

 Score =  165 bits (402), Expect = 8e-40
 Identities = 75/80 (93%), Positives = 80/80 (100%)
 Frame = +3

Query: 510 CKMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQES 689
           CKMRKRGCIVSKLLA+MMCKSGL+H+ITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQES
Sbjct: 103 CKMRKRGCIVSKLLAKMMCKSGLTHLITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQES 162

Query: 690 IPDYRNSVIVARNPGSAKKS 749
           IPD+RNSVIVARNPGSAKK+
Sbjct: 163 IPDFRNSVIVARNPGSAKKA 182



 Score =  159 bits (385), Expect = 9e-38
 Identities = 73/87 (83%), Positives = 81/87 (93%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLI 435
           PELA LIA+RLGV+ GGC+VY+KTNRET+VEI DS+RGK+IYIIQTGTKDVNNNIMELLI
Sbjct: 18  PELASLIADRLGVKNGGCAVYYKTNRETMVEIGDSVRGKDIYIIQTGTKDVNNNIMELLI 77

Query: 436 MAYACKTSSASSIVGVIPYLPYSKHAK 516
           MAYACKTSSA SIVGV+PYLPYSK  K
Sbjct: 78  MAYACKTSSAKSIVGVVPYLPYSKQCK 104


>UniRef50_O60256 Cluster: Phosphoribosyl pyrophosphate
           synthetase-associated protein 2; n=62; Eumetazoa|Rep:
           Phosphoribosyl pyrophosphate synthetase-associated
           protein 2 - Homo sapiens (Human)
          Length = 369

 Score =  146 bits (353), Expect = 7e-34
 Identities = 66/80 (82%), Positives = 75/80 (93%)
 Frame = +3

Query: 510 CKMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQES 689
           CKMRKRG IVSKLLA MMCK+GL+H+ITMDLHQKEIQGFF+ PVDNLRASPFLLQYIQE 
Sbjct: 117 CKMRKRGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEE 176

Query: 690 IPDYRNSVIVARNPGSAKKS 749
           IPDYRN+VIVA++P SAK++
Sbjct: 177 IPDYRNAVIVAKSPASAKRA 196



 Score =  116 bits (278), Expect = 8e-25
 Identities = 55/86 (63%), Positives = 65/86 (75%)
 Frame = +1

Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
           EL+  IA RLGV  G   VY + NRET V+I +S+RGK+++IIQT +KDVN  IMELLIM
Sbjct: 33  ELSKKIAERLGVEMGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIM 92

Query: 439 AYACKTSSASSIVGVIPYLPYSKHAK 516
            YACKTS A SI+GVIPY PYSK  K
Sbjct: 93  VYACKTSCAKSIIGVIPYFPYSKQCK 118


>UniRef50_A2AAG9 Cluster: Likely ortholog of H. sapiens
           phosphoribosyl pyrophosphate synthetase- associated
           protein 1; n=21; Coelomata|Rep: Likely ortholog of H.
           sapiens phosphoribosyl pyrophosphate synthetase-
           associated protein 1 - Mus musculus (Mouse)
          Length = 175

 Score =  130 bits (315), Expect = 3e-29
 Identities = 61/77 (79%), Positives = 69/77 (89%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           KMRKRG IV KLLA M+ K+GL+HIITMDLHQKEIQGFF  PVDNLRASPFLLQYIQE I
Sbjct: 99  KMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEI 158

Query: 693 PDYRNSVIVARNPGSAK 743
           P+YRN+VIVA++P +AK
Sbjct: 159 PNYRNAVIVAKSPDAAK 175



 Score =   99 bits (238), Expect = 6e-20
 Identities = 47/82 (57%), Positives = 62/82 (75%)
 Frame = +1

Query: 271 LIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYAC 450
           +++ RLG   G   VY +TN ET VEI +S+RG++I+IIQT  +DVN  +MELLIMAYA 
Sbjct: 18  VLSRRLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYAL 77

Query: 451 KTSSASSIVGVIPYLPYSKHAK 516
           KT+ A +I+GVIPY PYSK +K
Sbjct: 78  KTACARNIIGVIPYFPYSKQSK 99


>UniRef50_Q9VT33 Cluster: Ribose-phosphate pyrophosphokinase; n=4;
           Fungi/Metazoa group|Rep: Ribose-phosphate
           pyrophosphokinase - Drosophila melanogaster (Fruit fly)
          Length = 388

 Score = 93.9 bits (223), Expect = 4e-18
 Identities = 42/78 (53%), Positives = 59/78 (75%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           K R R  I +KL+A M+  +G  HIITMDLH  +IQGFFD PVDNL A P +L++I+E+I
Sbjct: 170 KFRSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENI 229

Query: 693 PDYRNSVIVARNPGSAKK 746
           P+++NS+IV+ + G AK+
Sbjct: 230 PEWKNSIIVSPDAGGAKR 247



 Score = 91.1 bits (216), Expect = 3e-17
 Identities = 44/96 (45%), Positives = 65/96 (67%), Gaps = 4/96 (4%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLI 435
           P+LA  I +RLG+  G       +N ET VEI +S+RG+++YI+Q+G+ ++N+N+MELLI
Sbjct: 60  PDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGSGEINDNLMELLI 119

Query: 436 MAYACKTSSASSIVGVIPYLPYSKHAK----CGNED 531
           M  ACK +SAS +  VIP  PY++  K     G+ED
Sbjct: 120 MINACKIASASRVTAVIPCFPYARQDKKDKLAGSED 155


>UniRef50_Q16GA3 Cluster: Ribose-phosphate pyrophosphokinase 1,
           putative; n=2; Aedes aegypti|Rep: Ribose-phosphate
           pyrophosphokinase 1, putative - Aedes aegypti
           (Yellowfever mosquito)
          Length = 330

 Score = 90.6 bits (215), Expect = 4e-17
 Identities = 41/87 (47%), Positives = 61/87 (70%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLI 435
           P+LA  I +RLG+  G       +N ET VEI +S+RG+++YI+Q+G+ ++N+N+MELLI
Sbjct: 49  PDLASRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGSGEINDNLMELLI 108

Query: 436 MAYACKTSSASSIVGVIPYLPYSKHAK 516
           M  ACK +SAS +  VIP  PY++  K
Sbjct: 109 MINACKIASASRVTAVIPCFPYARQDK 135


>UniRef50_A7M6E2 Cluster: Ribose-phosphate pyrophosphokinase I; n=1;
           Dugesia ryukyuensis|Rep: Ribose-phosphate
           pyrophosphokinase I - Dugesia ryukyuensis
          Length = 316

 Score = 89.8 bits (213), Expect = 6e-17
 Identities = 40/91 (43%), Positives = 63/91 (69%)
 Frame = +1

Query: 262 LADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMA 441
           L + I  R+G++     +   +N ET V+I +S+RGK+++I+Q+G  DVNN++MELLIM 
Sbjct: 15  LTEKIGERIGIKLSEAILNKFSNNETSVQIKESVRGKDVFILQSGYIDVNNHLMELLIMI 74

Query: 442 YACKTSSASSIVGVIPYLPYSKHAKCGNEDV 534
            ACK +S++ I  V+PY+PYS+ +K  N  V
Sbjct: 75  NACKNASSARITAVLPYMPYSRQSKKDNNRV 105



 Score = 62.5 bits (145), Expect = 1e-08
 Identities = 31/78 (39%), Positives = 49/78 (62%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           K   R  I +KL+A ++  +G +HIITMDLH  +IQGFF+ PVDNL +    + +I+++I
Sbjct: 100 KDNNRVPITAKLVADLLHIAGANHIITMDLHASQIQGFFNVPVDNLLSESCHISWIKKNI 159

Query: 693 PDYRNSVIVARNPGSAKK 746
             +    I + N  SA++
Sbjct: 160 SKWEEITIFSLNVTSAER 177


>UniRef50_Q0U4M1 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
           Phaeosphaeria nodorum|Rep: Ribose-phosphate
           pyrophosphokinase - Phaeosphaeria nodorum (Septoria
           nodorum)
          Length = 464

 Score = 89.8 bits (213), Expect = 6e-17
 Identities = 34/78 (43%), Positives = 60/78 (76%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           K + RG I ++++A ++  +G++H+IT+DLH  ++QGFF CPVDNL A P L ++I+ ++
Sbjct: 33  KKQHRGAITARMVANLLHVAGVNHVITLDLHASQMQGFFKCPVDNLVAEPLLSRWIRVNV 92

Query: 693 PDYRNSVIVARNPGSAKK 746
           P++R +V+V++NPG  K+
Sbjct: 93  PNWREAVVVSKNPGGTKR 110



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 20/32 (62%), Positives = 23/32 (71%)
 Frame = +1

Query: 421 MELLIMAYACKTSSASSIVGVIPYLPYSKHAK 516
           MELLIM  ACK  SA SI  V+PY PYS+ +K
Sbjct: 1   MELLIMISACKGGSAKSITAVMPYFPYSRQSK 32


>UniRef50_A7TNR7 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 433

 Score = 89.8 bits (213), Expect = 6e-17
 Identities = 37/79 (46%), Positives = 58/79 (73%), Gaps = 1/79 (1%)
 Frame = +3

Query: 513 KMRK-RGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQES 689
           KM+K RG I +++LA ++  +G  H+I+MDLH  ++QGFF  PVDNL   P L ++I+E+
Sbjct: 99  KMKKHRGAITARMLANLLIMAGADHVISMDLHSSQMQGFFSKPVDNLYGGPSLARWIKEN 158

Query: 690 IPDYRNSVIVARNPGSAKK 746
           + DY N+V+V++NPG  K+
Sbjct: 159 VEDYENAVVVSKNPGGTKR 177



 Score = 80.2 bits (189), Expect = 5e-14
 Identities = 38/87 (43%), Positives = 54/87 (62%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLI 435
           PEL +L+  RLGV    C +    N ET V+I  S+R +++Y+IQ+ +  +N++IMELLI
Sbjct: 13  PELGNLVCQRLGVEPAPCVLKKFVNGETSVQIGVSVRDEDVYVIQSSSNTLNDHIMELLI 72

Query: 436 MAYACKTSSASSIVGVIPYLPYSKHAK 516
           M  A    SA  +  VIP  PYSK +K
Sbjct: 73  MVSAFSGGSAGKVTAVIPMFPYSKQSK 99


>UniRef50_Q5A4X7 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
           Candida albicans|Rep: Ribose-phosphate pyrophosphokinase
           - Candida albicans (Yeast)
          Length = 404

 Score = 89.4 bits (212), Expect = 8e-17
 Identities = 41/87 (47%), Positives = 60/87 (68%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLI 435
           PEL  L+ +RLGV    C++   +N ET V+I  S+R +++YIIQ+G+  +N++IMELLI
Sbjct: 13  PELGQLVCDRLGVEPAPCTLKKFSNGETSVQIGVSVRDEDVYIIQSGSPHINDHIMELLI 72

Query: 436 MAYACKTSSASSIVGVIPYLPYSKHAK 516
           +  AC+  SA+ I  VIP  PYSK +K
Sbjct: 73  LISACRGGSANKITAVIPQFPYSKQSK 99



 Score = 87.8 bits (208), Expect = 3e-16
 Identities = 36/79 (45%), Positives = 58/79 (73%), Gaps = 1/79 (1%)
 Frame = +3

Query: 513 KMRK-RGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQES 689
           KM+K RG I +++LA ++  +G  H+++MDLH  ++QGFF  PVDNL  +P L ++I+  
Sbjct: 99  KMKKHRGAITARMLANLLVMAGADHVVSMDLHASQMQGFFSKPVDNLFGAPTLARWIRHH 158

Query: 690 IPDYRNSVIVARNPGSAKK 746
           IPD+ N+V+V++NPG  K+
Sbjct: 159 IPDWENAVVVSKNPGGTKR 177


>UniRef50_P32895 Cluster: Ribose-phosphate pyrophosphokinase 1;
           n=11; Ascomycota|Rep: Ribose-phosphate pyrophosphokinase
           1 - Saccharomyces cerevisiae (Baker's yeast)
          Length = 427

 Score = 89.0 bits (211), Expect = 1e-16
 Identities = 35/80 (43%), Positives = 59/80 (73%), Gaps = 1/80 (1%)
 Frame = +3

Query: 510 CKMRK-RGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQE 686
           CKM++ RG I +++LA ++  +G  H+++MDLH  ++QGFF  PVDNL   P L ++I+E
Sbjct: 98  CKMKRHRGAITARMLANLLVMAGADHVVSMDLHASQMQGFFTKPVDNLYGGPSLAKWIRE 157

Query: 687 SIPDYRNSVIVARNPGSAKK 746
           ++ DY ++V+V++NPG  K+
Sbjct: 158 NVEDYEDAVVVSKNPGGTKR 177



 Score = 87.0 bits (206), Expect = 4e-16
 Identities = 38/87 (43%), Positives = 57/87 (65%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLI 435
           PEL +++  RLG+    C++    N ET V+I  S+R +++Y+IQ+G+  +N++IMELLI
Sbjct: 13  PELGNMVCQRLGIEPAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPSINDDIMELLI 72

Query: 436 MAYACKTSSASSIVGVIPYLPYSKHAK 516
           +  AC+  SA  I  VIP  PYSK  K
Sbjct: 73  LVSACRGGSARKITAVIPQFPYSKQCK 99


>UniRef50_Q5KCA3 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
           Filobasidiella neoformans|Rep: Ribose-phosphate
           pyrophosphokinase - Cryptococcus neoformans
           (Filobasidiella neoformans)
          Length = 357

 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 38/79 (48%), Positives = 57/79 (72%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           K + R  I SKL+A ++  +G  H+ITMDLH  +IQGFFD PVDNL + P ++QYI+  I
Sbjct: 105 KDKSRAPITSKLVANLLAVAGADHVITMDLHASQIQGFFDIPVDNLFSEPTMMQYIKSEI 164

Query: 693 PDYRNSVIVARNPGSAKKS 749
           P +R+++IV+ + G AK++
Sbjct: 165 PGWRDAIIVSPDAGGAKRA 183



 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 40/88 (45%), Positives = 59/88 (67%), Gaps = 1/88 (1%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTK-DVNNNIMELL 432
           P+LA+ +A RLG+    C V    + ET V+I  S+R ++++IIQ+ +  DVN+++MELL
Sbjct: 17  PKLAEAVAARLGITLTPCHVSKFRSLETSVQIHSSVRDEDVFIIQSPSPPDVNDHLMELL 76

Query: 433 IMAYACKTSSASSIVGVIPYLPYSKHAK 516
           IM  ACKT+SA  I  VIP  PY++  K
Sbjct: 77  IMISACKTASAKRITAVIPCYPYARQDK 104


>UniRef50_P60891 Cluster: Ribose-phosphate pyrophosphokinase 1;
           n=156; Eukaryota|Rep: Ribose-phosphate pyrophosphokinase
           1 - Homo sapiens (Human)
          Length = 318

 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 40/86 (46%), Positives = 61/86 (70%)
 Frame = +1

Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
           +L+  IA+RLG+  G       +N+ET VEI +S+RG+++YI+Q+G  ++N+N+MELLIM
Sbjct: 14  DLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIM 73

Query: 439 AYACKTSSASSIVGVIPYLPYSKHAK 516
             ACK +SAS +  VIP  PY++  K
Sbjct: 74  INACKIASASRVTAVIPCFPYARQDK 99



 Score = 86.2 bits (204), Expect = 8e-16
 Identities = 40/78 (51%), Positives = 56/78 (71%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           K + R  I +KL+A M+  +G  HIITMDLH  +IQGFFD PVDNL A P +L++I+E+I
Sbjct: 100 KDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENI 159

Query: 693 PDYRNSVIVARNPGSAKK 746
            ++RN  IV+ + G AK+
Sbjct: 160 SEWRNCTIVSPDAGGAKR 177


>UniRef50_UPI000156094F Cluster: PREDICTED: similar to PRPS2
           protein; n=2; Mammalia|Rep: PREDICTED: similar to PRPS2
           protein - Equus caballus
          Length = 301

 Score = 87.0 bits (206), Expect = 4e-16
 Identities = 40/78 (51%), Positives = 56/78 (71%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           K + R  I +KL+A M+  +G  HIITMDLH  +IQGFFD PVDNL A P +LQ+I+E+I
Sbjct: 83  KDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENI 142

Query: 693 PDYRNSVIVARNPGSAKK 746
             ++N +IV+ + G AK+
Sbjct: 143 AQWKNCIIVSPDAGGAKR 160



 Score = 79.0 bits (186), Expect = 1e-13
 Identities = 33/66 (50%), Positives = 50/66 (75%)
 Frame = +1

Query: 319 HKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLP 498
           H  N +T+VEI +S+RG+++YIIQ+G  ++N+N+MELLIM  ACK +S+S +  VIP  P
Sbjct: 17  HTKNGKTLVEIGESVRGEDVYIIQSGCGEINDNLMELLIMINACKIASSSRVTAVIPCFP 76

Query: 499 YSKHAK 516
           Y++  K
Sbjct: 77  YARQDK 82


>UniRef50_Q1DW45 Cluster: Ribose-phosphate pyrophosphokinase; n=11;
           Ascomycota|Rep: Ribose-phosphate pyrophosphokinase -
           Coccidioides immitis
          Length = 509

 Score = 85.4 bits (202), Expect = 1e-15
 Identities = 38/87 (43%), Positives = 56/87 (64%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLI 435
           P L + I  RLG     C +   +N ET V I  S+R ++++I+Q+G+  +N+++MELLI
Sbjct: 13  PALTEAICERLGTVPAKCELRKFSNGETCVNIGVSVRNQDVFIVQSGSSKINDSVMELLI 72

Query: 436 MAYACKTSSASSIVGVIPYLPYSKHAK 516
           M  ACK  SA SI  V+PY PYS+ +K
Sbjct: 73  MISACKGGSAKSITAVLPYFPYSRQSK 99



 Score = 74.5 bits (175), Expect = 3e-12
 Identities = 30/78 (38%), Positives = 53/78 (67%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           K   RG I +++LA ++  +G+ H+IT+DLH  ++QGFF  PVDNL A   + ++I+ ++
Sbjct: 100 KKSHRGAITARMLANLLSIAGVDHVITVDLHASQMQGFFGKPVDNLFAESLIARWIRINV 159

Query: 693 PDYRNSVIVARNPGSAKK 746
           P +  +V+V +N G +K+
Sbjct: 160 PRWHEAVVVTKNAGGSKR 177


>UniRef50_A7EV32 Cluster: Putative uncharacterized protein; n=1;
           Sclerotinia sclerotiorum 1980|Rep: Putative
           uncharacterized protein - Sclerotinia sclerotiorum 1980
          Length = 526

 Score = 85.4 bits (202), Expect = 1e-15
 Identities = 32/78 (41%), Positives = 56/78 (71%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           K   RG I +++LA ++  +G++H+IT+DLH  ++QGFF CPVDNL A P + ++I+ ++
Sbjct: 100 KKSHRGAITARMLANLLHVAGINHVITVDLHASQMQGFFKCPVDNLHAEPLIARWIRRNV 159

Query: 693 PDYRNSVIVARNPGSAKK 746
           P++  +V V++N G  K+
Sbjct: 160 PEWNEAVCVSKNAGGTKR 177



 Score = 83.0 bits (196), Expect = 7e-15
 Identities = 38/87 (43%), Positives = 56/87 (64%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLI 435
           P+L D I   LG+      +    N ET V+I  SIR K+++++Q+G+  +N++IMELLI
Sbjct: 13  PKLTDQICTNLGMAAAPVELTQFANGETSVKIMTSIREKDVFVVQSGSSKINDSIMELLI 72

Query: 436 MAYACKTSSASSIVGVIPYLPYSKHAK 516
           M  ACK  SA+ I  V+PY PYS+ +K
Sbjct: 73  MISACKGGSANKITAVLPYFPYSRQSK 99


>UniRef50_Q4P1D3 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
           Ustilago maydis|Rep: Ribose-phosphate pyrophosphokinase
           - Ustilago maydis (Smut fungus)
          Length = 432

 Score = 83.0 bits (196), Expect = 7e-15
 Identities = 40/79 (50%), Positives = 54/79 (68%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           K + R  I +KL+A M+  +G  H+ITMDLH  +IQGFFD PVDNL A P  LQYI+E +
Sbjct: 113 KDKSRAPITAKLIANMLENAGCDHVITMDLHASQIQGFFDVPVDNLYAEPAALQYIREMV 172

Query: 693 PDYRNSVIVARNPGSAKKS 749
            D   +VIV+ + G AK++
Sbjct: 173 -DVNKAVIVSPDAGGAKRA 190



 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 42/96 (43%), Positives = 57/96 (59%), Gaps = 9/96 (9%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQT---------GTKDV 408
           PELA+LIA RLG   G  +V    + E+IV IA+S+R  ++YII T              
Sbjct: 17  PELAELIAKRLGQPLGKATVTRNESGESIVRIAESVREHDVYIINTSCVSPTPTGAAASP 76

Query: 409 NNNIMELLIMAYACKTSSASSIVGVIPYLPYSKHAK 516
           N ++MELLIM +ACKT+SA  I  VIP+  Y++  K
Sbjct: 77  NTSLMELLIMIHACKTASAKRITAVIPHFFYARQDK 112


>UniRef50_A1CDQ3 Cluster: Ribose-phosphate pyrophosphokinase; n=5;
           Pezizomycotina|Rep: Ribose-phosphate pyrophosphokinase -
           Aspergillus clavatus
          Length = 489

 Score = 82.6 bits (195), Expect = 1e-14
 Identities = 32/78 (41%), Positives = 56/78 (71%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           K   RG I +++LA ++  +G+ H+IT+DLH  ++QGFF  PVDNL A PF+ ++I+ ++
Sbjct: 101 KKSHRGAITARMLANLLSVAGVDHVITLDLHASQMQGFFGKPVDNLFAEPFIARWIRMNV 160

Query: 693 PDYRNSVIVARNPGSAKK 746
           P ++ +V+V++N G  K+
Sbjct: 161 PGWKEAVVVSKNAGGTKR 178



 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 38/88 (43%), Positives = 55/88 (62%), Gaps = 1/88 (1%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLI 435
           P LA+ I  RLG       +    N ET V+I  S+R +++YI+Q+G++ +N+++MELLI
Sbjct: 13  PVLAETICERLGTLPARALLGKFANGETRVDIGVSVRNQDVYILQSGSQKINDSVMELLI 72

Query: 436 MAYACKTSSASSIVGV-IPYLPYSKHAK 516
           M  ACK  SA SI G    Y PYS+ +K
Sbjct: 73  MISACKGGSAKSITGQWTRYFPYSRQSK 100


>UniRef50_A3LVW1 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
           Saccharomycetales|Rep: Ribose-phosphate
           pyrophosphokinase - Pichia stipitis (Yeast)
          Length = 451

 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 38/84 (45%), Positives = 54/84 (64%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLI 435
           P L   I   L + +G  S    +N ET +EI DS+R K+++I+Q+G  DVN+N +ELLI
Sbjct: 13  PSLTRTICRNLTIEQGEVSSRKFSNGETSLEIQDSVREKDVFIVQSGCGDVNDNFIELLI 72

Query: 436 MAYACKTSSASSIVGVIPYLPYSK 507
           M  ACKT+SA  +  V+P  PYS+
Sbjct: 73  MIAACKTASAKRVTAVLPLFPYSR 96



 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 31/68 (45%), Positives = 46/68 (67%)
 Frame = +3

Query: 546 LLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIPDYRNSVIVAR 725
           L+A ++  +G   +ITMDLH  + QGFF+ PVDNL + P L  YI + IP+Y+  VIV+ 
Sbjct: 215 LIANLLVTAGADRLITMDLHDPQFQGFFNIPVDNLYSRPLLKHYILDYIPNYQECVIVSP 274

Query: 726 NPGSAKKS 749
           + G AK++
Sbjct: 275 DSGGAKRA 282


>UniRef50_Q8X022 Cluster: Ribose-phosphate pyrophosphokinase; n=2;
           Pezizomycotina|Rep: Ribose-phosphate pyrophosphokinase -
           Neurospora crassa
          Length = 431

 Score = 81.0 bits (191), Expect = 3e-14
 Identities = 33/68 (48%), Positives = 51/68 (75%)
 Frame = +3

Query: 546 LLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIPDYRNSVIVAR 725
           L+A ++  +G  H+ITMDLH  ++QGFFD PVDNL   P L +YIQ+ IP++R++VI++ 
Sbjct: 202 LVANLLTCAGCDHVITMDLHDPQVQGFFDIPVDNLYGQPLLKRYIQQHIPNWRDAVIISP 261

Query: 726 NPGSAKKS 749
           + G AK++
Sbjct: 262 DAGGAKRA 269



 Score = 66.1 bits (154), Expect = 9e-10
 Identities = 36/88 (40%), Positives = 52/88 (59%), Gaps = 4/88 (4%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGT----KDVNNNIM 423
           PEL + I   LG+      +   ++ E+  EI DS+RGK++YIIQTG       +N++ M
Sbjct: 14  PELVESICGILGLPACSRILTKFSSGESRCEIQDSVRGKDVYIIQTGFGGNGSRLNDHFM 73

Query: 424 ELLIMAYACKTSSASSIVGVIPYLPYSK 507
           +L IM  ACKT SA  +  V+P  PYS+
Sbjct: 74  DLCIMISACKTGSARRVTAVLPLFPYSR 101


>UniRef50_Q4P9A7 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
           Ustilago maydis|Rep: Ribose-phosphate pyrophosphokinase
           - Ustilago maydis (Smut fungus)
          Length = 458

 Score = 80.6 bits (190), Expect = 4e-14
 Identities = 34/79 (43%), Positives = 55/79 (69%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           K + R  I +KL+A M+  +G  H+ITMDLH  +IQGFFD PVDNL + P + ++I+  +
Sbjct: 106 KDKSRAPITAKLVANMLTVAGADHVITMDLHASQIQGFFDIPVDNLTSEPSVARWIRSKV 165

Query: 693 PDYRNSVIVARNPGSAKKS 749
            ++R ++IV+ + G AK++
Sbjct: 166 ENWREAIIVSPDAGGAKRA 184



 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 39/90 (43%), Positives = 56/90 (62%), Gaps = 3/90 (3%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTK---DVNNNIME 426
           PELA  +A+RLG+    C      ++   V I  S+R +++Y++QTG     D N+++ME
Sbjct: 16  PELAQQVADRLGIPLTPCVCKKFADQSIDVRIGSSVRDEDVYVLQTGNSPYTDPNDSLME 75

Query: 427 LLIMAYACKTSSASSIVGVIPYLPYSKHAK 516
           LLI+  ACKT+SA  I  VIP  PYS+H K
Sbjct: 76  LLILLSACKTASARRITAVIPSFPYSRHDK 105


>UniRef50_A6R925 Cluster: Ribose-phosphate pyrophosphokinase I;
           n=20; Pezizomycotina|Rep: Ribose-phosphate
           pyrophosphokinase I - Ajellomyces capsulatus NAm1
          Length = 456

 Score = 79.8 bits (188), Expect = 7e-14
 Identities = 35/68 (51%), Positives = 49/68 (72%)
 Frame = +3

Query: 546 LLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIPDYRNSVIVAR 725
           L+A ++  +G  HIITMDLH  + QGFFD PVDNL   P L +YI E+IP+Y+ S+IV+ 
Sbjct: 247 LVADLLTCAGADHIITMDLHDPQYQGFFDIPVDNLYGRPLLKKYITENIPNYKASIIVSP 306

Query: 726 NPGSAKKS 749
           + G AK++
Sbjct: 307 DAGGAKRA 314



 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 36/86 (41%), Positives = 54/86 (62%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLI 435
           P L   I   LG+      +   +  ET VEI +S+RGK++YIIQ+G   VN+++MELL+
Sbjct: 14  PHLNKAICEHLGIPLANVLLSKFSVGETRVEINESVRGKDVYIIQSGGGKVNDHLMELLV 73

Query: 436 MAYACKTSSASSIVGVIPYLPYSKHA 513
           +  ACKT+SA  +  V+P  PYS+ +
Sbjct: 74  IISACKTASAKRVTAVLPLFPYSRQS 99


>UniRef50_Q6CG51 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
           Yarrowia lipolytica|Rep: Ribose-phosphate
           pyrophosphokinase - Yarrowia lipolytica (Candida
           lipolytica)
          Length = 370

 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 34/68 (50%), Positives = 47/68 (69%)
 Frame = +3

Query: 546 LLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIPDYRNSVIVAR 725
           L+A ++  +G  HIITMDLH  + QGFFD PVDNL   P L  YI   IP+Y+++VIV+ 
Sbjct: 154 LIASLLTCAGADHIITMDLHDPQFQGFFDIPVDNLYGKPLLQHYISTQIPNYQDAVIVSP 213

Query: 726 NPGSAKKS 749
           + G AK++
Sbjct: 214 DAGGAKRA 221



 Score = 76.6 bits (180), Expect = 6e-13
 Identities = 35/84 (41%), Positives = 51/84 (60%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLI 435
           P+L + I   L +      +    N ET V I DS+R K++Y++Q+G   VN+N +ELLI
Sbjct: 13  PKLVERICANLAIEPSNVDLAKFKNGETSVTIRDSVREKDVYVVQSGCGHVNDNFIELLI 72

Query: 436 MAYACKTSSASSIVGVIPYLPYSK 507
           M  ACKT+SA  +  V+P  PYS+
Sbjct: 73  MISACKTASAKKVTAVMPLFPYSR 96


>UniRef50_Q12265 Cluster: Probable ribose-phosphate
           pyrophosphokinase 5; n=6; Saccharomycetales|Rep:
           Probable ribose-phosphate pyrophosphokinase 5 -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 496

 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 33/68 (48%), Positives = 46/68 (67%)
 Frame = +3

Query: 546 LLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIPDYRNSVIVAR 725
           L+A ++  +G  H+ITMDLH  +  GFFD PVDNL   P    YIQ  IPDY+++VIV+ 
Sbjct: 225 LIAHLLSAAGADHVITMDLHDPQFPGFFDIPVDNLYCKPIAQNYIQHRIPDYQDAVIVSP 284

Query: 726 NPGSAKKS 749
           + G AK++
Sbjct: 285 DAGGAKRA 292



 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 34/84 (40%), Positives = 52/84 (61%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLI 435
           PEL   I   L +      +   +N ET + + +S+R K++YIIQ+G   VN+  M+LLI
Sbjct: 15  PELVTKICENLDIHPSKVELGKFSNGETNIALRESVREKDVYIIQSGCGQVNDTFMQLLI 74

Query: 436 MAYACKTSSASSIVGVIPYLPYSK 507
           +  ACK++SAS +  V+PYL YS+
Sbjct: 75  LISACKSASASRVTAVMPYLCYSR 98


>UniRef50_Q1AXL6 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
           Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
           Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
          Length = 331

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 36/84 (42%), Positives = 53/84 (63%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLI 435
           PELA+ IA+RL +  G   +   +N E      +S+RG +++I+Q+    VN N+MELL+
Sbjct: 24  PELAERIADRLDLELGSVELVQFSNGEVYARYLESVRGSDVFIVQSLCDPVNKNLMELLV 83

Query: 436 MAYACKTSSASSIVGVIPYLPYSK 507
           M  A K +SA SIV VIP+  YS+
Sbjct: 84  MVDAAKRASAESIVAVIPWYAYSR 107



 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 29/78 (37%), Positives = 48/78 (61%), Gaps = 1/78 (1%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRA-SPFLLQYIQES 689
           K + R  I ++L+A+M+  +G   I+TMDLH  +I+GFF  PVD+L A   F+  ++ E 
Sbjct: 111 KTKPREPITARLVAEMLKVAGADRIMTMDLHVGQIEGFFSFPVDHLTAMHTFVDHFVDEG 170

Query: 690 IPDYRNSVIVARNPGSAK 743
             +  ++V+VA + G  K
Sbjct: 171 FQNAPDTVVVAPDTGEVK 188


>UniRef50_A5DKD0 Cluster: Ribose-phosphate pyrophosphokinase; n=2;
           Saccharomycetaceae|Rep: Ribose-phosphate
           pyrophosphokinase - Pichia guilliermondii (Yeast)
           (Candida guilliermondii)
          Length = 472

 Score = 73.3 bits (172), Expect = 6e-12
 Identities = 33/84 (39%), Positives = 53/84 (63%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLI 435
           P+L   I   L   +   ++   +N ET +EI  S+R K+++IIQ+G+  +N+N ++LLI
Sbjct: 13  PDLTKSICRILTTEESDVNIGRFSNGETSIEIQGSVRDKDVFIIQSGSGHINDNFVQLLI 72

Query: 436 MAYACKTSSASSIVGVIPYLPYSK 507
           M  ACKT+SA  +  V+P  PYS+
Sbjct: 73  MIAACKTASARRVTAVLPLFPYSR 96



 Score = 69.7 bits (163), Expect = 7e-11
 Identities = 30/68 (44%), Positives = 45/68 (66%)
 Frame = +3

Query: 546 LLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIPDYRNSVIVAR 725
           L+A ++  +G    +TMDLH  + QGFF+ PVDNL + P L  YI + IP+Y+  VIV+ 
Sbjct: 232 LIANLLMTAGADRCVTMDLHDPQFQGFFNIPVDNLYSKPLLKHYIIDYIPNYQQCVIVSP 291

Query: 726 NPGSAKKS 749
           + G AK++
Sbjct: 292 DSGGAKRA 299


>UniRef50_P65239 Cluster: Ribose-phosphate pyrophosphokinase 1;
           n=143; Bacteria|Rep: Ribose-phosphate pyrophosphokinase
           1 - Streptococcus pneumoniae
          Length = 322

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 34/83 (40%), Positives = 56/83 (67%)
 Frame = +1

Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
           ELA+ +A  +G+  G  SV   ++ E  V I +SIRGK+++I+Q+ +  VN+N++E+LIM
Sbjct: 16  ELAERVAQEIGIELGKSSVRQFSDGEIQVNIEESIRGKHVFILQSTSSPVNDNLLEILIM 75

Query: 439 AYACKTSSASSIVGVIPYLPYSK 507
             A K +SA S+  V+PY  Y++
Sbjct: 76  VDALKRASAESVNVVMPYYGYAR 98



 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 29/79 (36%), Positives = 47/79 (59%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           K R R  I SKL+A M+  +G+  ++T+DLH  +IQGFFD PVD+L  +P +  Y +   
Sbjct: 102 KARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERRG 161

Query: 693 PDYRNSVIVARNPGSAKKS 749
               + V+V+ + G   ++
Sbjct: 162 MVGSDYVVVSPDHGGVTRA 180


>UniRef50_A5V1W5 Cluster: Ribose-phosphate pyrophosphokinase; n=5;
           Chloroflexi (class)|Rep: Ribose-phosphate
           pyrophosphokinase - Roseiflexus sp. RS-1
          Length = 327

 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 32/87 (36%), Positives = 52/87 (59%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLI 435
           P LA  I NRLGVR G  ++    N    V + +S+R K++++IQ+    +++ I+ELLI
Sbjct: 17  PALAQAICNRLGVRLGDVTITRFANENIFVRLNESVREKDVFVIQSLASPLSDRILELLI 76

Query: 436 MAYACKTSSASSIVGVIPYLPYSKHAK 516
           M  AC+ +SA  +  V+P+  Y +  K
Sbjct: 77  MLDACRRASAGRVTAVVPFYAYGRTDK 103



 Score = 53.2 bits (122), Expect = 7e-06
 Identities = 26/72 (36%), Positives = 45/72 (62%)
 Frame = +3

Query: 534 IVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIPDYRNSV 713
           I ++LLA M+  +G   ++T+DLH  +IQGFF  PVD L     L++Y ++    + + V
Sbjct: 111 ITARLLADMIQVAGAQQLVTIDLHAGQIQGFFSIPVDELSCMGLLVRYFRDR--GWDDVV 168

Query: 714 IVARNPGSAKKS 749
           +V+ + G AK++
Sbjct: 169 VVSSDIGFAKRA 180


>UniRef50_A0CY99 Cluster: Chromosome undetermined scaffold_31, whole
           genome shotgun sequence; n=2; Oligohymenophorea|Rep:
           Chromosome undetermined scaffold_31, whole genome
           shotgun sequence - Paramecium tetraurelia
          Length = 394

 Score = 70.5 bits (165), Expect = 4e-11
 Identities = 33/88 (37%), Positives = 58/88 (65%), Gaps = 1/88 (1%)
 Frame = +1

Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
           ELA+ IA  L ++ G  ++    + E  +++ D+IRGK+++IIQ+ +  VN+N+MELL++
Sbjct: 80  ELAEEIAEYLNIKLGSVTIGRFADGECQIQVLDNIRGKDVFIIQSTSPPVNDNLMELLLL 139

Query: 439 AYACKTSSASSIVGVIPYLPYSKH-AKC 519
             A + +SA  I+ V+PY  Y++   KC
Sbjct: 140 VSALRRASARKIIVVVPYYGYARQDRKC 167



 Score = 37.9 bits (84), Expect = 0.27
 Identities = 21/70 (30%), Positives = 41/70 (58%), Gaps = 3/70 (4%)
 Frame = +3

Query: 549 LAQMMCKSGLSHIITMDLHQKEIQGFFD--CPVDNLRASPFLLQYIQ-ESIPDYRNSVIV 719
           +A+++   G+  +I++DLH  +IQGFF    PVDNL A+     Y+  +   ++++  IV
Sbjct: 178 VARLLETVGVDRLISVDLHCGQIQGFFGPRVPVDNLEANLVAQNYLSLQKKYEFKDVAIV 237

Query: 720 ARNPGSAKKS 749
           + + G   ++
Sbjct: 238 SPDAGGVYRA 247


>UniRef50_A4VV92 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
           Streptococcus suis|Rep: Ribose-phosphate
           pyrophosphokinase - Streptococcus suis (strain 05ZYH33)
          Length = 333

 Score = 70.1 bits (164), Expect = 5e-11
 Identities = 34/83 (40%), Positives = 55/83 (66%)
 Frame = +1

Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
           ++A+ IA+  G+  G  S    ++ E  + I +S+RG ++YIIQ+ +  VNN++ ELLIM
Sbjct: 28  DIAEKIADSAGIPLGKLSSRQFSDGEIQINIEESVRGVDVYIIQSTSYPVNNHLWELLIM 87

Query: 439 AYACKTSSASSIVGVIPYLPYSK 507
             ACK +SA++I  VIPY  Y++
Sbjct: 88  IDACKRASANTITAVIPYFGYAR 110



 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 29/72 (40%), Positives = 42/72 (58%)
 Frame = +3

Query: 534 IVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIPDYRNSV 713
           I +KL+A M+ K+G+  ++T+DLH  +IQGFFD PVDNL   P    Y  E      + V
Sbjct: 121 ITAKLVANMLVKAGVDRVLTLDLHASQIQGFFDIPVDNLLTEPLFAAYYMEKGLCGEDVV 180

Query: 714 IVARNPGSAKKS 749
           IV+      K++
Sbjct: 181 IVSPKNSGIKRA 192


>UniRef50_Q8R753 Cluster: Ribose-phosphate pyrophosphokinase; n=18;
           Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
           Thermoanaerobacter tengcongensis
          Length = 316

 Score = 70.1 bits (164), Expect = 5e-11
 Identities = 37/90 (41%), Positives = 54/90 (60%)
 Frame = +1

Query: 238 FEWKLTPELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNN 417
           F     P+LA  IA  LG++     V   ++ E  V I +S+RG ++++IQ+    VNNN
Sbjct: 11  FTGNSNPKLASEIAEHLGLKLADSEVGTFSDGEISVRIGESVRGASVFVIQSTCAPVNNN 70

Query: 418 IMELLIMAYACKTSSASSIVGVIPYLPYSK 507
           +MELLIM  A K +SA+ I  VIPY  Y++
Sbjct: 71  LMELLIMIDAFKRASAAEINAVIPYYGYAR 100



 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 30/83 (36%), Positives = 52/83 (62%), Gaps = 2/83 (2%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQY-IQES 689
           K + R  I +KL+A ++  +G   ++TMDLH  +IQG+F+ PVD+L   P L +Y + + 
Sbjct: 104 KAKARDPITAKLVADLITAAGAHRVVTMDLHAPQIQGYFNIPVDHLLGGPILAKYFMDKE 163

Query: 690 IPDYRNSVIVARNPGSAKKS-YF 755
           + D  + V+V+ + GS  ++ YF
Sbjct: 164 LGD--DVVVVSPDHGSVTRARYF 184


>UniRef50_Q6MW31 Cluster: Related to ribose-phosphate
           pyrophosphokinase II; n=3; Sordariales|Rep: Related to
           ribose-phosphate pyrophosphokinase II - Neurospora
           crassa
          Length = 501

 Score = 69.7 bits (163), Expect = 7e-11
 Identities = 31/68 (45%), Positives = 46/68 (67%)
 Frame = +3

Query: 546 LLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIPDYRNSVIVAR 725
           L+A ++  +G   I+T DLH+   QGFFD PVD+L A P L +YIQ  I +Y+ +VIV+ 
Sbjct: 266 LIADLLTCAGADRIVTCDLHESTYQGFFDIPVDHLIARPLLKRYIQHHIENYKEAVIVSP 325

Query: 726 NPGSAKKS 749
           + G AK++
Sbjct: 326 DAGGAKRA 333



 Score = 44.4 bits (100), Expect = 0.003
 Identities = 19/40 (47%), Positives = 26/40 (65%)
 Frame = +1

Query: 388 QTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSK 507
           +TG   VN+  +EL IM  ACKT SA  +  V+P+ PYS+
Sbjct: 88  ETGHVTVNDYFIELCIMISACKTGSARRVTAVLPFFPYSR 127



 Score = 41.1 bits (92), Expect = 0.029
 Identities = 21/54 (38%), Positives = 30/54 (55%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNN 417
           P+  D + N LG+      +   ++ ET  EI DSIRGK++YIIQ+     N N
Sbjct: 14  PKFVDSVCNYLGIPPASRVLEKFSSGETRCEIRDSIRGKDVYIIQSFGVGTNRN 67


>UniRef50_Q7MT83 Cluster: Ribose-phosphate pyrophosphokinase; n=25;
           Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
           Porphyromonas gingivalis (Bacteroides gingivalis)
          Length = 313

 Score = 69.7 bits (163), Expect = 7e-11
 Identities = 32/79 (40%), Positives = 53/79 (67%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           K + R  I +KL+A ++ K+G++ +ITMDLH  +IQGFFD PVD+L  S   ++YI++++
Sbjct: 102 KDKPRVSIGAKLIADLLSKAGITRLITMDLHADQIQGFFDVPVDHLYGSTVFMEYIRKNM 161

Query: 693 PDYRNSVIVARNPGSAKKS 749
           P   N V+   + G  K++
Sbjct: 162 P-LENLVVATPDVGGTKRA 179



 Score = 59.7 bits (138), Expect = 8e-08
 Identities = 31/82 (37%), Positives = 51/82 (62%)
 Frame = +1

Query: 262 LADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMA 441
           LA+ I N LG   G  ++ H  + E  V   +SIRG++++++Q+ T   ++N+MELL+M 
Sbjct: 18  LAEKICNSLGCPLGRMNIEHFADGEFAVSYEESIRGRDVFLVQS-TFPSSDNLMELLLMI 76

Query: 442 YACKTSSASSIVGVIPYLPYSK 507
            A K +SA  I  VIPY  +++
Sbjct: 77  DAAKRASAHYITAVIPYFGWAR 98


>UniRef50_Q88Z84 Cluster: Ribose-phosphate pyrophosphokinase 1;
           n=77; Bacteria|Rep: Ribose-phosphate pyrophosphokinase 1
           - Lactobacillus plantarum
          Length = 326

 Score = 69.7 bits (163), Expect = 7e-11
 Identities = 37/82 (45%), Positives = 55/82 (67%)
 Frame = +1

Query: 262 LADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMA 441
           LA+ IA+ +GV+ G  SV   ++ E  + I +SIRG  +YIIQ+ +  VN+N+MELLIM 
Sbjct: 21  LAEKIADAVGVKLGKTSVDRFSDGEIRINIEESIRGDQVYIIQSTSAPVNDNLMELLIMI 80

Query: 442 YACKTSSASSIVGVIPYLPYSK 507
            A + +SA +I  VIPY  Y++
Sbjct: 81  DALRRASAKTINVVIPYYGYAR 102



 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 30/79 (37%), Positives = 47/79 (59%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           K R R  I +KL+A M+  +G + I+ +DLH  +IQGFFD P+D+L  +P L  Y     
Sbjct: 106 KARSREPITAKLVANMLETAGATRILALDLHAAQIQGFFDIPLDHLMGAPLLADYFLNHH 165

Query: 693 PDYRNSVIVARNPGSAKKS 749
            D  N+V+V+ + G   ++
Sbjct: 166 LD-ENAVVVSPDHGGVTRA 183


>UniRef50_Q6Z2L5-2 Cluster: Isoform 2 of Q6Z2L5 ; n=1; Oryza sativa
           (japonica cultivar-group)|Rep: Isoform 2 of Q6Z2L5 -
           Oryza sativa subsp. japonica (Rice)
          Length = 365

 Score = 68.9 bits (161), Expect = 1e-10
 Identities = 32/90 (35%), Positives = 53/90 (58%)
 Frame = +1

Query: 238 FEWKLTPELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNN 417
           F     P L+  IA+ LG+  G  ++    + E  V++ +S+RG +++++Q      N N
Sbjct: 83  FSGTANPSLSQEIASYLGLELGKINIKRFADGEIYVQLQESVRGCDVFLVQPTCPPANEN 142

Query: 418 IMELLIMAYACKTSSASSIVGVIPYLPYSK 507
           +MELLIM  AC+ +SA +I  VIPY  Y++
Sbjct: 143 LMELLIMIDACRRASAKNITAVIPYFGYAR 172


>UniRef50_UPI00006CD8E2 Cluster: ribose-phosphate pyrophosphokinase
           family protein; n=1; Tetrahymena thermophila SB210|Rep:
           ribose-phosphate pyrophosphokinase family protein -
           Tetrahymena thermophila SB210
          Length = 447

 Score = 68.5 bits (160), Expect = 2e-10
 Identities = 31/91 (34%), Positives = 55/91 (60%), Gaps = 1/91 (1%)
 Frame = +1

Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTK-DVNNNIMELLI 435
           ELA  + ++L ++    S++     ET +EI DS+RGK +++IQ+  +  +N+NIMEL +
Sbjct: 109 ELAKEVVSQLDIQLSRISIHKNPESETEIEILDSVRGKRVFVIQSLCQPSINDNIMELYL 168

Query: 436 MAYACKTSSASSIVGVIPYLPYSKHAKCGNE 528
           M  A K S A+ +  ++PY  YS+     ++
Sbjct: 169 MCSALKRSGAAKVTCIVPYFAYSRQTSAESD 199


>UniRef50_A4T068 Cluster: Ribose-phosphate pyrophosphokinase; n=20;
           Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
           Polynucleobacter sp. QLW-P1DMWA-1
          Length = 321

 Score = 67.7 bits (158), Expect = 3e-10
 Identities = 35/90 (38%), Positives = 53/90 (58%)
 Frame = +1

Query: 238 FEWKLTPELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNN 417
           F     P LA+ +A  L +  G   V   ++ E  VEI +++RGKN+ +IQ+     N++
Sbjct: 12  FTGNANPVLAEAVAKELKLPMGKAFVGRFSDGEIQVEIQENVRGKNVVVIQSTCAPTNDS 71

Query: 418 IMELLIMAYACKTSSASSIVGVIPYLPYSK 507
           +MEL+IM  A K +SAS I  VIPY  Y++
Sbjct: 72  LMELMIMIDALKRASASRITAVIPYFGYAR 101



 Score = 56.4 bits (130), Expect = 7e-07
 Identities = 29/76 (38%), Positives = 48/76 (63%), Gaps = 1/76 (1%)
 Frame = +3

Query: 525 RGCIVSKLLAQMMCK-SGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIPDY 701
           R  I ++++A M+   +G+  ++TMDLH  +IQGFFD PVDN+ ASP LL  +Q      
Sbjct: 110 RVAISARIVANMLQSVAGIERVLTMDLHADQIQGFFDIPVDNIYASPVLLADLQAQ-KTQ 168

Query: 702 RNSVIVARNPGSAKKS 749
           ++ +IV+ + G   ++
Sbjct: 169 KDLIIVSPDIGGVVRA 184


>UniRef50_Q9U465 Cluster: Phosphoribosylpyrophosphate synthetase;
           n=11; cellular organisms|Rep:
           Phosphoribosylpyrophosphate synthetase - Plasmodium
           falciparum
          Length = 323

 Score = 67.3 bits (157), Expect = 4e-10
 Identities = 33/90 (36%), Positives = 51/90 (56%)
 Frame = +1

Query: 238 FEWKLTPELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNN 417
           F     P L+  +A+ LG   G  ++    + E  ++  +SIRGK++YIIQ     VN N
Sbjct: 7   FSGTSNPLLSKNVADHLGTSLGRVNLKRFADGEVSMQFLESIRGKDVYIIQPTCPPVNEN 66

Query: 418 IMELLIMAYACKTSSASSIVGVIPYLPYSK 507
           ++ELL+M   C+ +SA  I  VIPY  Y++
Sbjct: 67  LIELLLMISTCRRASAKKITAVIPYYGYAR 96



 Score = 42.3 bits (95), Expect = 0.013
 Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 2/81 (2%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFD--CPVDNLRASPFLLQYIQE 686
           K+  R  I +  +A+M+   G+  ++ +DLH  +IQGFF    PVDNL A    L Y  +
Sbjct: 100 KLSSRVPISAADVARMIEAMGVDRVVAIDLHSGQIQGFFGPRVPVDNLEAQLIGLDYFTK 159

Query: 687 SIPDYRNSVIVARNPGSAKKS 749
              D    VIV+ + G   ++
Sbjct: 160 K--DLYKPVIVSPDAGGVYRA 178


>UniRef50_Q42581 Cluster: Ribose-phosphate pyrophosphokinase 1;
           n=145; cellular organisms|Rep: Ribose-phosphate
           pyrophosphokinase 1 - Arabidopsis thaliana (Mouse-ear
           cress)
          Length = 403

 Score = 67.3 bits (157), Expect = 4e-10
 Identities = 32/90 (35%), Positives = 51/90 (56%)
 Frame = +1

Query: 238 FEWKLTPELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNN 417
           F     P LA  IA  +G+  G  ++    + E  V++ +S+RG ++Y++Q      N N
Sbjct: 96  FSGTANPALAQEIAWYMGLDLGKVNIKRFADGEIYVQLQESVRGCDVYLVQPTCTPTNEN 155

Query: 418 IMELLIMAYACKTSSASSIVGVIPYLPYSK 507
           +MELLIM  AC+ +SA  +  VIPY  Y++
Sbjct: 156 LMELLIMVDACRRASAKKVTAVIPYFGYAR 185



 Score = 52.8 bits (121), Expect = 9e-06
 Identities = 25/80 (31%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYI-QES 689
           K + R  I +KL+A ++ ++G   ++  DLH  +  G+FD PVD++   P +L Y+  +S
Sbjct: 189 KTQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYCQPVILDYLASKS 248

Query: 690 IPDYRNSVIVARNPGSAKKS 749
           IP   + V+V+ + G   ++
Sbjct: 249 IPS-EDLVVVSPDVGGVARA 267


>UniRef50_A5URX1 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
           Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
           Roseiflexus sp. RS-1
          Length = 315

 Score = 66.9 bits (156), Expect = 5e-10
 Identities = 32/88 (36%), Positives = 50/88 (56%)
 Frame = +1

Query: 253 TPELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELL 432
           +P+L   I   LGV  G C V   +     V I +++RG+++YI+Q+     N+N MELL
Sbjct: 14  SPKLTKNICAYLGVTPGQCEVLRFSEGNLFVRILENVRGRHVYIVQSTAYPANDNFMELL 73

Query: 433 IMAYACKTSSASSIVGVIPYLPYSKHAK 516
               A K +SA+S+  V+P+  Y+K  K
Sbjct: 74  FWIDAFKRASAASVTAVVPFFSYAKGDK 101



 Score = 53.2 bits (122), Expect = 7e-06
 Identities = 29/79 (36%), Positives = 45/79 (56%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           K   R  I +++ A  +  +G   I+ MDLH  +IQGFF  PVD+L A P L   +++  
Sbjct: 102 KDEPRVSIRARVCADAIEAAGADRIVVMDLHAPQIQGFFKIPVDDLYALPVLCDRVRQM- 160

Query: 693 PDYRNSVIVARNPGSAKKS 749
            +  N ++VA + G AKK+
Sbjct: 161 -NLENLIVVAPDSGFAKKA 178


>UniRef50_A3ZLP4 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
           Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
           Blastopirellula marina DSM 3645
          Length = 328

 Score = 66.5 bits (155), Expect = 7e-10
 Identities = 33/90 (36%), Positives = 51/90 (56%)
 Frame = +1

Query: 238 FEWKLTPELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNN 417
           F  +  P LA  I   L +  G  ++    + E   +I + +RG+++++IQ     VNNN
Sbjct: 13  FSGRANPRLAGDICKFLNIPLGRITLGEFPDGENACKIEEDVRGRDVFLIQPTCPPVNNN 72

Query: 418 IMELLIMAYACKTSSASSIVGVIPYLPYSK 507
           IMELLIM  +C+ +SA  I  VIPY  Y++
Sbjct: 73  IMELLIMIDSCRRASAERITAVIPYFGYAR 102



 Score = 59.3 bits (137), Expect = 1e-07
 Identities = 30/73 (41%), Positives = 49/73 (67%), Gaps = 1/73 (1%)
 Frame = +3

Query: 534 IVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQE-SIPDYRNS 710
           I +KL++ ++  +G   ++TMDLH  +IQGFF+ PVD+L A+P L  + Q  +IP+    
Sbjct: 113 ITAKLVSDVITAAGADRVLTMDLHAAQIQGFFNVPVDHLYAAPVLNHFFQALNIPE-DEL 171

Query: 711 VIVARNPGSAKKS 749
           VIV+ + GS K++
Sbjct: 172 VIVSPDAGSIKRA 184


>UniRef50_Q8G5P2 Cluster: Ribose-phosphate pyrophosphokinase; n=56;
           Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
           Bifidobacterium longum
          Length = 340

 Score = 66.5 bits (155), Expect = 7e-10
 Identities = 34/90 (37%), Positives = 53/90 (58%)
 Frame = +1

Query: 247 KLTPELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIME 426
           ++ P+LA+ +A +LG+     + Y   N E  V   +S+RG +++++Q+  K +N  IME
Sbjct: 20  RIHPKLAEDVAEQLGIDVLETTAYDFANGEMYVRYTESVRGADVFVLQSHYKPINKAIME 79

Query: 427 LLIMAYACKTSSASSIVGVIPYLPYSKHAK 516
            LIM  A K +SA SI  V P L YS+  K
Sbjct: 80  QLIMIDALKRASARSITAVCPLLGYSRQDK 109



 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 26/69 (37%), Positives = 42/69 (60%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           K R R  I  +L+  ++  +G   I+++DLH  + QGFFD PVD+L A P L+ YI++  
Sbjct: 110 KHRGREPISCRLVFDLLKTAGADRIMSVDLHAAQSQGFFDGPVDHLVAMPVLVDYIRDRF 169

Query: 693 PDYRNSVIV 719
             + ++V V
Sbjct: 170 QGHLDNVAV 178


>UniRef50_Q8D2K5 Cluster: PrsA protein; n=1; Wigglesworthia
           glossinidia endosymbiont of Glossina brevipalpis|Rep:
           PrsA protein - Wigglesworthia glossinidia brevipalpis
          Length = 305

 Score = 66.1 bits (154), Expect = 9e-10
 Identities = 36/93 (38%), Positives = 57/93 (61%), Gaps = 1/93 (1%)
 Frame = +1

Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
           +L++ IAN LG+      +    + E  ++I +++RG+ ++IIQ+    VN+N MEL+I 
Sbjct: 11  KLSNKIANLLGISISNSEINKFQDGEINIKINENVRGEEVFIIQSMCFPVNDNFMELVIT 70

Query: 439 AYACKTSSASSIVGVIPYLPYSKH-AKCGNEDV 534
           A A K +SA  I+ VIPYL YS+   +  NE V
Sbjct: 71  ADALKRASAKKIIAVIPYLGYSRQDRRVYNEQV 103



 Score = 46.0 bits (104), Expect = 0.001
 Identities = 17/39 (43%), Positives = 30/39 (76%)
 Frame = +3

Query: 534 IVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNL 650
           I +K++A ++  SG+ H+I +DLH ++IQGFFD  +D++
Sbjct: 105 ITAKMIANLLAASGICHVIIVDLHCEQIQGFFDIILDSI 143


>UniRef50_Q8IE40 Cluster: Ribose-phosphate pyrophosphokinase,
           putative; n=4; Plasmodium|Rep: Ribose-phosphate
           pyrophosphokinase, putative - Plasmodium falciparum
           (isolate 3D7)
          Length = 560

 Score = 66.1 bits (154), Expect = 9e-10
 Identities = 35/89 (39%), Positives = 53/89 (59%), Gaps = 3/89 (3%)
 Frame = +1

Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQT---GTKDVNNNIMEL 429
           ELA+ I + LG+  G   V   ++ E  ++I D +RG++IYII +   G KDV++ +MEL
Sbjct: 186 ELANEICSNLGIGLGRAYVGKFSDGEIALQIMDEVRGRDIYIIHSTPAGGKDVHSRLMEL 245

Query: 430 LIMAYACKTSSASSIVGVIPYLPYSKHAK 516
            +     + SSA  +  VIPYL YS+  K
Sbjct: 246 FLFISTLRRSSAKKVTAVIPYLNYSRQTK 274


>UniRef50_Q3M5L4 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
           Anabaena variabilis ATCC 29413|Rep: Ribose-phosphate
           pyrophosphokinase - Anabaena variabilis (strain ATCC
           29413 / PCC 7937)
          Length = 310

 Score = 65.3 bits (152), Expect = 2e-09
 Identities = 31/93 (33%), Positives = 55/93 (59%)
 Frame = +1

Query: 238 FEWKLTPELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNN 417
           F     P+LA  +A +L +  G  +V    + E  V + +S+R K+++I+Q+    VN++
Sbjct: 7   FAGTANPDLAGTVAQKLDIPLGKSAVERFPDGEVNVRLLESVRQKSVFILQSTAPPVNDH 66

Query: 418 IMELLIMAYACKTSSASSIVGVIPYLPYSKHAK 516
           ++ELL  A AC+ ++AS I  +IPY  Y++  K
Sbjct: 67  LVELLAFADACRRAAASRITAIIPYFGYARADK 99



 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 25/71 (35%), Positives = 46/71 (64%)
 Frame = +3

Query: 522 KRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIPDY 701
           +R  I + ++A+++   G++H++T+DLH  +I+GFF  PVD+L A P   + I+  +P  
Sbjct: 103 RREPITASMVAEVLQAVGVNHVVTLDLHTLQIEGFFRIPVDSLTAVPIFCEAIRHYLPP- 161

Query: 702 RNSVIVARNPG 734
            N V+V+ + G
Sbjct: 162 -NFVVVSPDTG 171


>UniRef50_A4EBQ1 Cluster: Putative uncharacterized protein; n=1;
           Collinsella aerofaciens ATCC 25986|Rep: Putative
           uncharacterized protein - Collinsella aerofaciens ATCC
           25986
          Length = 328

 Score = 65.3 bits (152), Expect = 2e-09
 Identities = 33/77 (42%), Positives = 49/77 (63%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           K   R  I ++L+A ++ ++G+  IIT+DLHQ +IQGFFD PV++L A P   QY  +  
Sbjct: 113 KAGPREPITARLVANLLERAGVDRIITLDLHQGQIQGFFDIPVNHLSALPLFGQYYNDMH 172

Query: 693 PDYRNSVIVARNPGSAK 743
            D  N V+V+ + G AK
Sbjct: 173 FDTDNLVVVSPDVGRAK 189



 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 30/83 (36%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
 Frame = +1

Query: 262 LADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQT-GTKDVNNNIMELLIM 438
           LA  IA  LGV   G ++    N E      +++RG ++++IQ+    +VN+ +MELLI 
Sbjct: 27  LAQKIAEYLGVELSGLTLKQFANGEIYARYDETVRGADVFLIQSVAGGNVNDMLMELLIA 86

Query: 439 AYACKTSSASSIVGVIPYLPYSK 507
             A K +SA SI  VI +  Y++
Sbjct: 87  TDAAKRASARSITAVITHYGYAR 109


>UniRef50_Q6MAT0 Cluster: Probable phosphoribosyl pyrophosphate
           synthetase; n=1; Candidatus Protochlamydia amoebophila
           UWE25|Rep: Probable phosphoribosyl pyrophosphate
           synthetase - Protochlamydia amoebophila (strain UWE25)
          Length = 313

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 30/70 (42%), Positives = 48/70 (68%)
 Frame = +3

Query: 534 IVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIPDYRNSV 713
           I +KL+A ++ ++G++ I+TMDLH  ++QGFFD PVD+L     L+  +Q+   D  NS+
Sbjct: 110 ITAKLVANLLVEAGITRILTMDLHVDQLQGFFDIPVDHLSGRQLLIDELQKL--DLTNSI 167

Query: 714 IVARNPGSAK 743
           +VA + GS K
Sbjct: 168 VVAPDIGSVK 177



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 34/93 (36%), Positives = 53/93 (56%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLI 435
           P LA  IA +L +  G   +    + E  V++ +S+RGK+ +++Q+   D N  +MELLI
Sbjct: 16  PILATEIAQQLKISLGQMQLSKFPDGEIGVQLLESVRGKDTFVLQSIALDPNFYLMELLI 75

Query: 436 MAYACKTSSASSIVGVIPYLPYSKHAKCGNEDV 534
           +  A K +SA +IV VIPY  Y +  +    DV
Sbjct: 76  IVDALKRASARNIVAVIPYYGYCRQDRKDKFDV 108


>UniRef50_Q4XQD5 Cluster: Ribose-phosphate pyrophosphokinase,
           putative; n=1; Plasmodium chabaudi|Rep: Ribose-phosphate
           pyrophosphokinase, putative - Plasmodium chabaudi
          Length = 465

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 32/89 (35%), Positives = 54/89 (60%), Gaps = 3/89 (3%)
 Frame = +1

Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQT---GTKDVNNNIMEL 429
           ELA+ I + LG+  G   +   ++ E  ++I D +RG+++YII +   G KDV++ +MEL
Sbjct: 113 ELANEICSNLGISLGRAYIGKYSDGEITLQIMDEVRGRDVYIIHSTPAGGKDVHSRLMEL 172

Query: 430 LIMAYACKTSSASSIVGVIPYLPYSKHAK 516
            +     + SSA  ++ V+PYL YS+  K
Sbjct: 173 FLFVSTLRRSSAKKVIVVLPYLNYSRQNK 201


>UniRef50_Q83GR1 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
           Actinomycetales|Rep: Ribose-phosphate pyrophosphokinase
           - Tropheryma whipplei (strain Twist) (Whipple's
           bacillus)
          Length = 348

 Score = 64.1 bits (149), Expect = 4e-09
 Identities = 32/89 (35%), Positives = 49/89 (55%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLI 435
           P+LA   A  LGV      +    N E       S+RGK+++++QTG   VN+ ++ELL+
Sbjct: 43  PDLARATAESLGVGLLQTDIRTFANGEIYTRFNSSVRGKDVFVLQTGCDPVNDGLVELLL 102

Query: 436 MAYACKTSSASSIVGVIPYLPYSKHAKCG 522
           +  +CK +SA  I  V P  PYS+  + G
Sbjct: 103 LIDSCKRASAKHISAVTPCYPYSRQDRKG 131



 Score = 52.0 bits (119), Expect = 2e-05
 Identities = 27/70 (38%), Positives = 44/70 (62%)
 Frame = +3

Query: 534 IVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIPDYRNSV 713
           I ++L+A ++  +G   IIT+DLH  +IQGFF+ PVD+L   P L+++++    D  N  
Sbjct: 137 ISARLVADLIACAGADRIITVDLHASQIQGFFNGPVDHLTGVPALIKHVKSLRID--NLT 194

Query: 714 IVARNPGSAK 743
           IV+ + G  K
Sbjct: 195 IVSPDIGRVK 204


>UniRef50_Q6F241 Cluster: Ribose-phosphate pyrophosphokinase; n=6;
           Mollicutes|Rep: Ribose-phosphate pyrophosphokinase -
           Mesoplasma florum (Acholeplasma florum)
          Length = 347

 Score = 64.1 bits (149), Expect = 4e-09
 Identities = 35/83 (42%), Positives = 49/83 (59%)
 Frame = +1

Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
           ELA  I + LGV++         + E ++E  DS+RGK I++IQ+ +  VN +IMELLI 
Sbjct: 18  ELAQEICDILGVKRKEVKTLKFADGEILIESLDSVRGKEIFVIQSTSTPVNESIMELLIA 77

Query: 439 AYACKTSSASSIVGVIPYLPYSK 507
             A K  SA  I  VIPY  Y++
Sbjct: 78  IDAFKRGSAEKINVVIPYYGYAR 100



 Score = 48.0 bits (109), Expect = 3e-04
 Identities = 25/78 (32%), Positives = 44/78 (56%), Gaps = 4/78 (5%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           K + R  I SKL+A ++ K+G   ++++D+H  +  GFFD P+DN   +  L   I ++I
Sbjct: 104 KAKGRQPITSKLVADLLTKAGADRVMSIDIHSPQSMGFFDVPMDNFYTAQTLATEIIDTI 163

Query: 693 P----DYRNSVIVARNPG 734
                D  N ++V+ + G
Sbjct: 164 ELNNWDPSNCILVSPDYG 181


>UniRef50_Q9RUD2 Cluster: Probable ribose-phosphate
           pyrophosphokinase; n=7; Bacteria|Rep: Probable
           ribose-phosphate pyrophosphokinase - Deinococcus
           radiodurans
          Length = 320

 Score = 63.7 bits (148), Expect = 5e-09
 Identities = 26/72 (36%), Positives = 46/72 (63%)
 Frame = +3

Query: 534 IVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIPDYRNSV 713
           I  +L+A ++ ++G   ++TM LH  ++ GFF  PVD+L A   L Q+ ++ +PD  N V
Sbjct: 111 IAGRLVADLLQEAGADRVLTMTLHSPQVHGFFKVPVDHLSADVVLSQHFKKCVPDAHNGV 170

Query: 714 IVARNPGSAKKS 749
           ++A + GS K++
Sbjct: 171 VLAPDAGSIKRA 182



 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 32/85 (37%), Positives = 49/85 (57%)
 Frame = +1

Query: 262 LADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMA 441
           LA  I + LGV  G       TN   IV   +S+R  +++I+QT +  V++ IMEL++M 
Sbjct: 19  LAQAICDNLGVPLGRSRTEKFTNDNLIVHYEESLREGDVFIVQTFSTPVSDAIMELMLMI 78

Query: 442 YACKTSSASSIVGVIPYLPYSKHAK 516
            A K++SA  +  VIPY  Y++  K
Sbjct: 79  DAAKSASAGRVTAVIPYYSYARSDK 103


>UniRef50_A0VM43 Cluster: Ribose-phosphate pyrophosphokinase; n=20;
           Proteobacteria|Rep: Ribose-phosphate pyrophosphokinase -
           Dinoroseobacter shibae DFL 12
          Length = 340

 Score = 63.3 bits (147), Expect = 6e-09
 Identities = 31/80 (38%), Positives = 48/80 (60%), Gaps = 1/80 (1%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASP-FLLQYIQES 689
           + + R  I +KL+A MM ++G+  ++TMDLH  +IQGFFD PVDNL A+P F L  +   
Sbjct: 109 RTKARTPITAKLVANMMVEAGIERVLTMDLHAAQIQGFFDIPVDNLYAAPIFALDVMHNF 168

Query: 690 IPDYRNSVIVARNPGSAKKS 749
                N  +V+ + G   ++
Sbjct: 169 AGRLDNVTVVSPDVGGVARA 188



 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 32/89 (35%), Positives = 53/89 (59%), Gaps = 6/89 (6%)
 Frame = +1

Query: 259 ELADLIANRLGVRKG------GCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNI 420
           ELA  I+ R+   +G         V    + E  VE+ +++RG++++IIQ+ +   N+N+
Sbjct: 17  ELAHAISRRMSAYRGMTVGLVDARVERFNDGEIFVEVFENVRGEDMFIIQSTSNPANDNL 76

Query: 421 MELLIMAYACKTSSASSIVGVIPYLPYSK 507
           MELLIM  A + SSA+ I  +IPY  Y++
Sbjct: 77  MELLIMCDALRRSSAARITAIIPYFGYAR 105


>UniRef50_Q075L4 Cluster: Plastid ribose-phosphate diphosphokinase;
           n=1; Prototheca wickerhamii|Rep: Plastid
           ribose-phosphate diphosphokinase - Prototheca
           wickerhamii
          Length = 213

 Score = 63.3 bits (147), Expect = 6e-09
 Identities = 31/90 (34%), Positives = 51/90 (56%)
 Frame = +1

Query: 238 FEWKLTPELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNN 417
           F     P L+  +   LG+  G  S+    + E  V++ +SIRG ++++IQ     VN+ 
Sbjct: 121 FSGTANPGLSQEVVCYLGLELGAISIKRFADGEIYVQVGESIRGCDVFLIQPTAPPVNDA 180

Query: 418 IMELLIMAYACKTSSASSIVGVIPYLPYSK 507
           ++ELLI   AC+ +SA SI  V+PY  Y++
Sbjct: 181 LVELLITIDACRRASARSITAVLPYFGYAR 210


>UniRef50_Q75JN8 Cluster: Similar to ribose-phosphate
           pyrophosphokinase; n=3; Dictyostelium discoideum|Rep:
           Similar to ribose-phosphate pyrophosphokinase -
           Dictyostelium discoideum (Slime mold)
          Length = 329

 Score = 63.3 bits (147), Expect = 6e-09
 Identities = 30/75 (40%), Positives = 46/75 (61%), Gaps = 1/75 (1%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYI-QES 689
           K + R  I  KL+A MM  +G+  +ITMDLH  +IQGFF+ PV+N+   P  ++YI ++ 
Sbjct: 103 KDKSRAPITCKLVANMMEAAGIDRVITMDLHSSQIQGFFNIPVENVYTEPLFVKYIKKKK 162

Query: 690 IPDYRNSVIVARNPG 734
             ++ N   V  +PG
Sbjct: 163 KTEFLNQEFVIVSPG 177



 Score = 59.3 bits (137), Expect = 1e-07
 Identities = 33/88 (37%), Positives = 50/88 (56%), Gaps = 1/88 (1%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQ-TGTKDVNNNIMELL 432
           P+L+  IA+ L    G   V    N ET V I +S+R  ++YI+Q T    VN+ +MELL
Sbjct: 15  PKLSKEIASCLNTEVGNALVSKFANSETQVIINESVRDVDLYIVQPTCNPSVNDYLMELL 74

Query: 433 IMAYACKTSSASSIVGVIPYLPYSKHAK 516
           +M    K +SA  I  V+P+  Y++ +K
Sbjct: 75  VMVDGAKRASAHRITAVVPFFGYARQSK 102


>UniRef50_Q1GEV9 Cluster: Ribose-phosphate pyrophosphokinase; n=11;
           Alphaproteobacteria|Rep: Ribose-phosphate
           pyrophosphokinase - Silicibacter sp. (strain TM1040)
          Length = 340

 Score = 61.3 bits (142), Expect = 3e-08
 Identities = 27/69 (39%), Positives = 43/69 (62%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           + + R  I +K++A M+  +G+  ++TMDLH  +IQGFFD PVDNL ASP     ++   
Sbjct: 109 RTKARTPISAKMVANMLTGAGIERVLTMDLHAAQIQGFFDIPVDNLYASPIFALDVKAQF 168

Query: 693 PDYRNSVIV 719
            D  + ++V
Sbjct: 169 KDQMDDLMV 177



 Score = 59.3 bits (137), Expect = 1e-07
 Identities = 32/88 (36%), Positives = 52/88 (59%), Gaps = 6/88 (6%)
 Frame = +1

Query: 262 LADLIANRLGVRKG------GCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIM 423
           LA  I+ R+ + +G         V    + E  VE+ +++RG++++IIQ  +   N+N+M
Sbjct: 18  LAKSISRRMSMHRGVDQDLVNARVERFNDGEIFVEVYENVRGEDMFIIQPTSNPANDNLM 77

Query: 424 ELLIMAYACKTSSASSIVGVIPYLPYSK 507
           ELLI+A A + SSA  I  VIPY  Y++
Sbjct: 78  ELLIIADALRRSSAQRITAVIPYFGYAR 105


>UniRef50_UPI00005A2C8C Cluster: PREDICTED: similar to
           Ribose-phosphate pyrophosphokinase I (Phosphoribosyl
           pyrophosphate synthetase I) (PRS-I); n=1; Canis lupus
           familiaris|Rep: PREDICTED: similar to Ribose-phosphate
           pyrophosphokinase I (Phosphoribosyl pyrophosphate
           synthetase I) (PRS-I) - Canis familiaris
          Length = 339

 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 31/86 (36%), Positives = 50/86 (58%)
 Frame = +1

Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
           +L+  IA+ LG+          +++ET VE+  S RG++ Y +Q+G    ++ +MELLIM
Sbjct: 56  DLSQEIAHHLGLELCRLVTKKFSDQETCVEMGKSERGEDNYTVQSGCGHTSDGLMELLIM 115

Query: 439 AYACKTSSASSIVGVIPYLPYSKHAK 516
              CK +SA  +  VIP  PY++  K
Sbjct: 116 INTCKIASAHWVTAVIPCFPYARQGK 141



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 27/53 (50%), Positives = 39/53 (73%), Gaps = 2/53 (3%)
 Frame = +3

Query: 594 MDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIPDYRNSVIVA--RNPGSAKK 746
           +DLH  +IQGFFD PVD++RA P +L+ I+ESI ++RN  +V+  R P  AK+
Sbjct: 151 LDLHTSQIQGFFDIPVDHVRAEPAVLKCIRESISEWRNCTVVSPDRCPWGAKR 203


>UniRef50_Q4Q3Z4 Cluster: Phosphoribosylpyrophosphate synthetase,
           putative; n=6; Trypanosomatidae|Rep:
           Phosphoribosylpyrophosphate synthetase, putative -
           Leishmania major
          Length = 356

 Score = 59.7 bits (138), Expect = 8e-08
 Identities = 31/88 (35%), Positives = 48/88 (54%), Gaps = 4/88 (4%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGT----KDVNNNIM 423
           P+L D +A  L V K    +    N E  +++ D++RG + +IIQ        DVN  +M
Sbjct: 45  PDLTDNVAKCLNVDKCRTEIKRFANGELNIKVVDNVRGDDCFIIQPTAGGFDTDVNTAMM 104

Query: 424 ELLIMAYACKTSSASSIVGVIPYLPYSK 507
           ELL++ +  K SSA  I  ++PY  YS+
Sbjct: 105 ELLLLVHTLKLSSAKRITAIVPYYAYSR 132



 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 27/81 (33%), Positives = 46/81 (56%), Gaps = 2/81 (2%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFF-DCPVDNLRASPFLLQYI-QE 686
           K   R  I +  +AQ++   G+  ++TMDLH  +IQGFF + PVDNL   P    Y+ ++
Sbjct: 136 KSEPRVPISASAVAQLLQCMGVDRVVTMDLHCGQIQGFFRNIPVDNLLMFPEFATYLTRQ 195

Query: 687 SIPDYRNSVIVARNPGSAKKS 749
              D   +V+V+ + G  +++
Sbjct: 196 PWFDKNQTVVVSPDAGGVERA 216


>UniRef50_Q89DJ1 Cluster: Ribose-phosphate pyrophosphokinase; n=310;
           Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
           Bradyrhizobium japonicum
          Length = 317

 Score = 59.7 bits (138), Expect = 8e-08
 Identities = 26/79 (32%), Positives = 51/79 (64%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           K   R  I +KL+A ++ ++G+  ++T+DLH  +IQGFFD P DNL A+P +++ I++  
Sbjct: 104 KSGSRTPISAKLVANLITQAGVDRVMTLDLHAGQIQGFFDIPTDNLYAAPLMVRDIKDKF 163

Query: 693 PDYRNSVIVARNPGSAKKS 749
            D   +++++ + G   ++
Sbjct: 164 -DLSKTMVISPDVGGVARA 181



 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 31/84 (36%), Positives = 48/84 (57%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLI 435
           P LA  IA  L +      V    + E  VEI +++RG + +IIQ+ +   N+++MELLI
Sbjct: 17  PALAQAIAQGLHLPLTKAVVRRFADMEIFVEIQENVRGSDAFIIQSTSFPANDHLMELLI 76

Query: 436 MAYACKTSSASSIVGVIPYLPYSK 507
           +  A + SSA  I  V+PY  Y++
Sbjct: 77  ITDALRRSSARRITAVLPYFGYAR 100


>UniRef50_Q8Y9L8 Cluster: Ribose-phosphate pyrophosphokinase 2;
           n=15; Bacilli|Rep: Ribose-phosphate pyrophosphokinase 2
           - Listeria monocytogenes
          Length = 311

 Score = 59.7 bits (138), Expect = 8e-08
 Identities = 28/70 (40%), Positives = 48/70 (68%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           K R R  I +KL+A ++ ++G + +IT+DLH  +IQGFF+ P+D+L A P +  Y+ E+ 
Sbjct: 101 KARSREPITAKLMANLIQRAGANRLITVDLHAAQIQGFFNIPIDHLSAIPLIGDYLIENY 160

Query: 693 PDYRNSVIVA 722
            + ++ V+VA
Sbjct: 161 GE-KDVVVVA 169



 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 30/82 (36%), Positives = 47/82 (57%)
 Frame = +1

Query: 262 LADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMA 441
           LA  IA+ L +      +   ++ E  + I +SIRG N Y++Q+   +VN  +MELLIM 
Sbjct: 16  LATKIADYLDIPLCEVELQKFSDGEVKINIEESIRGTNAYVVQSMNSNVNERLMELLIMV 75

Query: 442 YACKTSSASSIVGVIPYLPYSK 507
            A K +S  SI  ++PY  Y++
Sbjct: 76  DALKRASVHSINIIMPYYGYAR 97


>UniRef50_Q03YB5 Cluster: Ribose-phosphate pyrophosphokinase; n=2;
           Lactobacillales|Rep: Ribose-phosphate pyrophosphokinase
           - Leuconostoc mesenteroides subsp. mesenteroides (strain
           ATCC 8293 /NCDO 523)
          Length = 323

 Score = 59.3 bits (137), Expect = 1e-07
 Identities = 31/83 (37%), Positives = 49/83 (59%)
 Frame = +1

Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
           ELA  I+  LGV      +    + E    I +++RG+N+Y+IQ  T  VN+N M+L+I 
Sbjct: 15  ELAGEISTILGVPLAPIDIKTFADNEIYERIENTVRGRNVYVIQGITAPVNDNFMKLMIF 74

Query: 439 AYACKTSSASSIVGVIPYLPYSK 507
             A + +SA+SI  +IPY  Y++
Sbjct: 75  IDAARRASANSINVIIPYFGYAR 97



 Score = 56.8 bits (131), Expect = 5e-07
 Identities = 29/79 (36%), Positives = 46/79 (58%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           K R R  I ++++A M+   G+  ++TMDLH  ++QGFFD PVD+L A P L  Y   + 
Sbjct: 101 KARSREPISARMIANMLESQGVKRVMTMDLHADQVQGFFDIPVDHLLAMPALGHYFYAND 160

Query: 693 PDYRNSVIVARNPGSAKKS 749
               + V+VA +  S  ++
Sbjct: 161 LLGDDLVVVAPDHSSVARA 179


>UniRef50_P75044 Cluster: Ribose-phosphate pyrophosphokinase; n=6;
           Mycoplasma|Rep: Ribose-phosphate pyrophosphokinase -
           Mycoplasma pneumoniae
          Length = 328

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 30/93 (32%), Positives = 49/93 (52%)
 Frame = +1

Query: 229 HCYFEWKLTPELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDV 408
           H  F    T +L   I  +L +  G  +     + ET +   +S+R K+++I Q+    V
Sbjct: 6   HVVFSLSKTHDLVSRICQKLKMPMGLITHNEFADGETYIRFEESVRNKDVFIFQSTCAPV 65

Query: 409 NNNIMELLIMAYACKTSSASSIVGVIPYLPYSK 507
           N+++MELLI   A K  SA SI  ++PY  Y++
Sbjct: 66  NDSLMELLIAIDALKRGSAKSITAILPYYGYAR 98



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 27/82 (32%), Positives = 44/82 (53%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           K   R  I SKL+A ++  +G+S +   D+H  + QGFF+ PVD LR     L    E +
Sbjct: 102 KTMGREPITSKLVADLLTTAGVSRVALTDIHSDQTQGFFNIPVDTLRTYHVFLTRTVELL 161

Query: 693 PDYRNSVIVARNPGSAKKSYFI 758
              ++ V+V+ + G  K++  I
Sbjct: 162 -GKKDLVVVSPDYGGVKRARLI 182


>UniRef50_UPI0000EB04C8 Cluster: UPI0000EB04C8 related cluster; n=1;
           Canis lupus familiaris|Rep: UPI0000EB04C8 UniRef100
           entry - Canis familiaris
          Length = 298

 Score = 58.4 bits (135), Expect = 2e-07
 Identities = 30/69 (43%), Positives = 43/69 (62%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           K +    I +K +A M+  +G  HIITMDLH  ++QGFF+ PVDNL   P +L    E+I
Sbjct: 102 KDKSHALISAKPVANML--AGADHIITMDLHDSQVQGFFNIPVDNLSVEPAIL----ENI 155

Query: 693 PDYRNSVIV 719
             +RN +I+
Sbjct: 156 AKWRNCIII 164



 Score = 56.0 bits (129), Expect = 1e-06
 Identities = 24/60 (40%), Positives = 41/60 (68%)
 Frame = +1

Query: 325 TNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYS 504
           +N+ET +E++ + +GK++Y IQ+G  ++ NN+M L IM    K +++S +  VIP  PYS
Sbjct: 37  SNQETSLEVSGNRKGKDVYNIQSGYGEIKNNLMGLFIMINTDKITASSRVTSVIPCFPYS 96


>UniRef50_Q822W0 Cluster: Ribose-phosphate pyrophosphokinase; n=2;
           Chlamydophila|Rep: Ribose-phosphate pyrophosphokinase -
           Chlamydophila caviae
          Length = 301

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 29/82 (35%), Positives = 49/82 (59%)
 Frame = +1

Query: 262 LADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMA 441
           LA  +   L ++ G   +    + ET V++ + +RG++++I+Q+     N+ + ELLI+A
Sbjct: 16  LAQNVCAELKIKLGRMELNQFPDGETHVKVLEDVRGRDVFIMQSIVGQPNHYLFELLIIA 75

Query: 442 YACKTSSASSIVGVIPYLPYSK 507
            A K SSA SI  +IPYL Y +
Sbjct: 76  DALKRSSAKSITAIIPYLGYCR 97



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 22/70 (31%), Positives = 42/70 (60%)
 Frame = +3

Query: 534 IVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIPDYRNSV 713
           I +KL+A ++  +G++++IT DLH  +I+GF+   VD+L      +  I+  I   ++ +
Sbjct: 108 ITAKLVADVLTTAGITNLITCDLHADQIEGFYKTHVDHLHCQQLFVDTIKSCIS--QDCI 165

Query: 714 IVARNPGSAK 743
            +A + GS K
Sbjct: 166 AIAPDIGSIK 175


>UniRef50_Q74LT0 Cluster: Phosphoribosylpyrophosphate synthetase;
           n=5; Lactobacillus|Rep: Phosphoribosylpyrophosphate
           synthetase - Lactobacillus johnsonii
          Length = 329

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 33/82 (40%), Positives = 49/82 (59%)
 Frame = +1

Query: 262 LADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMA 441
           LA+ IA  L       +V H ++ E  V I +S+RG ++Y+IQ+    VN N MEL+I+ 
Sbjct: 24  LAERIAAALDKPLLETAVQHFSDGEIQVNITESVRGCDVYVIQSIQDPVNENFMELMIVL 83

Query: 442 YACKTSSASSIVGVIPYLPYSK 507
            A   +SA S+  VIPY+ YS+
Sbjct: 84  DALHRASAHSVNVVIPYMAYSR 105



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 29/74 (39%), Positives = 43/74 (58%), Gaps = 1/74 (1%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQY-IQES 689
           K R R  I +KLLA ++  + +  +I +DLH  +IQGF++ PVD+L A P L QY +   
Sbjct: 109 KNRSREPITAKLLANLLQLTDIDDLIAVDLHASQIQGFYNIPVDHLHAMPILAQYFLDNG 168

Query: 690 IPDYRNSVIVARNP 731
           I    N  +V  +P
Sbjct: 169 IASKENDDVVVVSP 182


>UniRef50_Q4Q0M2 Cluster: Phosphoribosylpyrophosphate synthetase,
           putative; n=6; Trypanosomatidae|Rep:
           Phosphoribosylpyrophosphate synthetase, putative -
           Leishmania major
          Length = 358

 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 32/89 (35%), Positives = 52/89 (58%), Gaps = 5/89 (5%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQ-----TGTKDVNNNI 420
           P+LA+ +   L +      V    N ETIV+I +SIRG +I++IQ     +   +VN  +
Sbjct: 20  PKLAEDVCRYLNIPVTASRVGSFANGETIVKILESIRGDDIFVIQPTCSNSAGTNVNQAV 79

Query: 421 MELLIMAYACKTSSASSIVGVIPYLPYSK 507
           MELL++ +  K SSA  ++ VIP+  Y++
Sbjct: 80  MELLLIIHTLKLSSARRVIAVIPHYGYAR 108



 Score = 52.8 bits (121), Expect = 9e-06
 Identities = 26/77 (33%), Positives = 47/77 (61%), Gaps = 1/77 (1%)
 Frame = +3

Query: 534 IVSKLLAQMMCKSGLSHIITMDLHQKEIQGFF-DCPVDNLRASPFLLQYIQESIPDYRNS 710
           I +  +A+M+ + G++ ++TMDLH  +IQGFF  CPV +L  S    +Y+++      N 
Sbjct: 119 ISASAVARMVTEMGVNGVVTMDLHCGQIQGFFHGCPVADLSPSSEFAEYVKQKNFTPNNL 178

Query: 711 VIVARNPGSAKKSYFIC 761
           V+VA + G+  ++  +C
Sbjct: 179 VVVAPDAGAVNRARRMC 195


>UniRef50_A0E424 Cluster: Chromosome undetermined scaffold_77, whole
           genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_77,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 371

 Score = 56.4 bits (130), Expect = 7e-07
 Identities = 27/90 (30%), Positives = 49/90 (54%)
 Frame = +1

Query: 238 FEWKLTPELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNN 417
           F      +LA  +A  LG+  G   +    + E  +++ +++RG+N +IIQ+    VN N
Sbjct: 48  FSGNSNTKLASEVAKCLGISLGKVLLERFADGECNIQVLENVRGRNAFIIQSTCPPVNEN 107

Query: 418 IMELLIMAYACKTSSASSIVGVIPYLPYSK 507
           ++EL +   A + +S  +I  +IPY  YS+
Sbjct: 108 LVELFLFISALRRASVKTITVIIPYYGYSR 137



 Score = 40.3 bits (90), Expect = 0.051
 Identities = 19/54 (35%), Positives = 37/54 (68%), Gaps = 2/54 (3%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFF--DCPVDNLRASPFL 668
           K+ K   I +  +A+++ ++G+ H++++DLH+ ++QG F    PVDNL  SP++
Sbjct: 141 KLAKTESIAAADIAKILEQTGIDHLVSIDLHRGQLQGAFSTSVPVDNL--SPYI 192


>UniRef50_Q0G092 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
           Fulvimarina pelagi HTCC2506|Rep: Ribose-phosphate
           pyrophosphokinase - Fulvimarina pelagi HTCC2506
          Length = 307

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 27/72 (37%), Positives = 43/72 (59%)
 Frame = +3

Query: 534 IVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIPDYRNSV 713
           I +KL+A ++  +G   ++T+DLH  +IQGFFD P DNL A P   + I+E   D  N  
Sbjct: 89  ISAKLVANLITHAGADRVMTLDLHAGQIQGFFDIPTDNLFAIPLFARDIKEH-QDLSNLT 147

Query: 714 IVARNPGSAKKS 749
           +V+ + G   ++
Sbjct: 148 VVSPDVGGVVRA 159



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 25/78 (32%), Positives = 49/78 (62%)
 Frame = +1

Query: 274 IANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACK 453
           +A  L +  G   V    ++E  VEI +++RG++++++Q+ +   N+++MELLI+  A +
Sbjct: 1   MAKYLELPVGEALVRRFADQEIFVEIQENVRGEDVFVVQSTSYPANDHLMELLIIIDAMR 60

Query: 454 TSSASSIVGVIPYLPYSK 507
            +SA  I  V+PY  Y++
Sbjct: 61  RASARRITAVLPYFGYAR 78


>UniRef50_A7HHV4 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
           Cystobacterineae|Rep: Ribose-phosphate pyrophosphokinase
           - Anaeromyxobacter sp. Fw109-5
          Length = 311

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 25/84 (29%), Positives = 48/84 (57%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLI 435
           PEL   +A RLG+      V    + E  V + + +RG  +Y++Q  +   + +++EL+ 
Sbjct: 12  PELTREVAERLGLTSAERVVERFPDGELRVVVKEPVRGAEVYLVQPLSPPADAHLLELVF 71

Query: 436 MAYACKTSSASSIVGVIPYLPYSK 507
           +A AC+ + A S+  V+PYL +++
Sbjct: 72  LADACRRAGARSVTAVVPYLAWAR 95



 Score = 45.2 bits (102), Expect = 0.002
 Identities = 21/67 (31%), Positives = 41/67 (61%)
 Frame = +3

Query: 549 LAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIPDYRNSVIVARN 728
           LA  +  +    ++++D+H    +GFF  P+D+L A+P L   I  S+P  R++V+V  +
Sbjct: 110 LAADLISARADRVVSVDVHGPAAEGFFSVPLDHLTAAPALAAAIARSVP--RDAVVVGPD 167

Query: 729 PGSAKKS 749
            G+A+++
Sbjct: 168 LGAARRA 174


>UniRef50_Q9PQV0 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
           Ureaplasma parvum|Rep: Ribose-phosphate
           pyrophosphokinase - Ureaplasma parvum (Ureaplasma
           urealyticum biotype 1)
          Length = 330

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 31/83 (37%), Positives = 49/83 (59%)
 Frame = +1

Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
           +LA+ IAN L +      +    + E IV     +RG+ + IIQ+ +K VN+++MELLI 
Sbjct: 17  QLANKIANLLKIELSPIRIDKFADGELIVAPQVPVRGRRVIIIQSTSKPVNDSLMELLIA 76

Query: 439 AYACKTSSASSIVGVIPYLPYSK 507
             + K +SA +I  VIPY  Y++
Sbjct: 77  IDSIKRASAKAISVVIPYYGYAR 99



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 26/79 (32%), Positives = 47/79 (59%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           K + R  I ++L+A+M+  +G + ++T D+H  + QGFFD P D+L A   L+++   + 
Sbjct: 103 KAKPREPITARLVAKMIESAGATSVLTWDIHSLQTQGFFDIPFDSLEAVWVLMKHYFSAY 162

Query: 693 PDYRNSVIVARNPGSAKKS 749
            D  N  IV+ + G  K++
Sbjct: 163 KDSSNITIVSPDYGGVKRA 181


>UniRef50_Q5GTH9 Cluster: Phosphoribosylpyrophosphate synthetase;
           n=6; Wolbachia|Rep: Phosphoribosylpyrophosphate
           synthetase - Wolbachia sp. subsp. Brugia malayi (strain
           TRS)
          Length = 308

 Score = 54.0 bits (124), Expect = 4e-06
 Identities = 29/83 (34%), Positives = 45/83 (54%)
 Frame = +1

Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
           EL  LIAN+L V+     V    +     E+  ++  + +YIIQ+ +  VN+++MELL +
Sbjct: 11  ELGKLIANKLNVQPFSAQVSKFADGAINAEVESNLCSQEVYIIQSISPPVNDHLMELLFI 70

Query: 439 AYACKTSSASSIVGVIPYLPYSK 507
             A K S    I  +IPY  YS+
Sbjct: 71  IDAVKRSGTKRITTIIPYYGYSR 93



 Score = 41.1 bits (92), Expect = 0.029
 Identities = 16/37 (43%), Positives = 26/37 (70%)
 Frame = +3

Query: 540 SKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNL 650
           +KL+A ++  +G S +  +DLH  +I+GFFD P+ NL
Sbjct: 109 AKLVANLIQTAGASSVAVIDLHSSQIEGFFDVPLTNL 145


>UniRef50_Q8EUI1 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
           Mycoplasma penetrans|Rep: Ribose-phosphate
           pyrophosphokinase - Mycoplasma penetrans
          Length = 332

 Score = 53.2 bits (122), Expect = 7e-06
 Identities = 28/78 (35%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           K + R  I  KL+A  +  +G + +I +D+H ++ QGFFD PVD L AS  L    +++ 
Sbjct: 104 KAKGREPITCKLVANFLEGAGATKVILIDIHSEQTQGFFDIPVDTLTASCVLFNEFRKNN 163

Query: 693 PD-YRNSVIVARNPGSAK 743
           P   +N  +VA + G+ K
Sbjct: 164 PSVIKNLTVVAPDYGAVK 181



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 23/78 (29%), Positives = 45/78 (57%)
 Frame = +1

Query: 274 IANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACK 453
           +A +  ++ G        + E +V+   ++RG ++++ Q+    VN+N+MELLI   + K
Sbjct: 23  VAEKTNIQLGTIKTSKFADGEILVKSNSTVRGMHVFLFQSTCNPVNDNLMELLIAIDSLK 82

Query: 454 TSSASSIVGVIPYLPYSK 507
            +SA +I  +IPY  Y++
Sbjct: 83  RASAKTITVIIPYFGYAR 100


>UniRef50_Q4UNC9 Cluster: Ribose-phosphate pyrophosphokinase; n=9;
           Rickettsia|Rep: Ribose-phosphate pyrophosphokinase -
           Rickettsia felis (Rickettsia azadi)
          Length = 293

 Score = 52.8 bits (121), Expect = 9e-06
 Identities = 26/77 (33%), Positives = 45/77 (58%)
 Frame = +3

Query: 516 MRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIP 695
           +  +  I +KL+A  + K G++H+IT+DLH  +I+ FF+ P+ NL      + +++    
Sbjct: 97  INSQNIIPAKLIADFLEKLGVNHVITIDLHSDKIEKFFNIPISNLEPINLYIPFLR---- 152

Query: 696 DYRNSVIVARNPGSAKK 746
            Y N VIVA + GS  +
Sbjct: 153 TYSNFVIVAPDKGSINR 169



 Score = 49.6 bits (113), Expect = 8e-05
 Identities = 24/91 (26%), Positives = 52/91 (57%)
 Frame = +1

Query: 262 LADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMA 441
           LA  +A  L ++     + +  + E  VEI +S   +++ I+Q+ +K VN+ ++EL ++ 
Sbjct: 12  LASRLAIALNIKYIEPRITYFNDSEIKVEIQESFHNEDVIIVQSTSKPVNDRLIELFLLV 71

Query: 442 YACKTSSASSIVGVIPYLPYSKHAKCGNEDV 534
            A K + A+ I+ V+PY  Y++     ++++
Sbjct: 72  DAAKKAVANRIILVMPYFGYARQDNINSQNI 102


>UniRef50_Q2GIZ1 Cluster: Ribose-phosphate pyrophosphokinase; n=6;
           Anaplasmataceae|Rep: Ribose-phosphate pyrophosphokinase
           - Anaplasma phagocytophilum (strain HZ)
          Length = 322

 Score = 52.0 bits (119), Expect = 2e-05
 Identities = 20/50 (40%), Positives = 33/50 (66%)
 Frame = +3

Query: 540 SKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQES 689
           +K++A+++  SGL HI+T+DLH ++  GFFD P  N+ A    + Y+  S
Sbjct: 116 AKVIARILSTSGLDHIVTLDLHSQQAAGFFDVPFTNISAYDVFVDYLSSS 165


>UniRef50_Q98R83 Cluster: Ribose-phosphate pyrophosphokinase; n=10;
           Mycoplasma|Rep: Ribose-phosphate pyrophosphokinase -
           Mycoplasma pulmonis
          Length = 321

 Score = 50.8 bits (116), Expect = 4e-05
 Identities = 26/77 (33%), Positives = 47/77 (61%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
           K   R  I +KLLA ++  +G+S I+ +DLH   IQGFF+ PVD+++A   L +  + +I
Sbjct: 102 KAEGRQPIAAKLLADLLQVAGISRIVVVDLHNPSIQGFFNIPVDDIKAQYILSK--EFTI 159

Query: 693 PDYRNSVIVARNPGSAK 743
            D + +++   + G+ +
Sbjct: 160 KDEKFTIVSPDHGGTIR 176



 Score = 45.2 bits (102), Expect = 0.002
 Identities = 24/90 (26%), Positives = 48/90 (53%)
 Frame = +1

Query: 238 FEWKLTPELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNN 417
           F    T  LA  I + L ++    +     + E ++   +++R K+++I+ + +   NNN
Sbjct: 9   FSMPNTHVLAQEICDELKMKLHSVNKTIFADGEVLLSSKETVRSKDVFIVASTSHPANNN 68

Query: 418 IMELLIMAYACKTSSASSIVGVIPYLPYSK 507
           IM+LLI   + K +SA +I  ++ Y  Y++
Sbjct: 69  IMDLLIFVDSLKRASAKTINVILSYYGYAR 98


>UniRef50_Q4QI56 Cluster: Phosphoribosylpyrophosphate synthetase;
           n=8; Trypanosomatidae|Rep: Phosphoribosylpyrophosphate
           synthetase - Leishmania major
          Length = 370

 Score = 49.6 bits (113), Expect = 8e-05
 Identities = 28/86 (32%), Positives = 48/86 (55%), Gaps = 4/86 (4%)
 Frame = +1

Query: 262 LADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQ--TGTK--DVNNNIMEL 429
           LA+ +A  +G      SV   +N E  V I + + G ++YIIQ  TG +  D+N  +MEL
Sbjct: 58  LAEAVALLMGTHTHHTSVTQYSNGEVNVRINECVLGADVYIIQSTTGNEIIDINTALMEL 117

Query: 430 LIMAYACKTSSASSIVGVIPYLPYSK 507
           L++    + S+A S+  + P+  Y++
Sbjct: 118 LLLIRKMRLSNAKSVTVIAPFFGYAR 143



 Score = 49.6 bits (113), Expect = 8e-05
 Identities = 27/82 (32%), Positives = 49/82 (59%), Gaps = 3/82 (3%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFD-CPVDNLRASPFLLQYIQES 689
           K   RG I + ++A+M+ K G++ + ++DLH  +IQGFFD  PVDNL  +    +Y+ + 
Sbjct: 147 KTSLRGPISASVVARMVVKMGVNRLASLDLHSNQIQGFFDNIPVDNLLMAHEFARYLHDQ 206

Query: 690 IPDYR--NSVIVARNPGSAKKS 749
            P +     V+V+ + G  +++
Sbjct: 207 -PWFNVDQMVVVSPDAGGVERA 227


>UniRef50_A7ARJ1 Cluster: Ribose-phosphate pyrophosphokinase,
           putative; n=1; Babesia bovis|Rep: Ribose-phosphate
           pyrophosphokinase, putative - Babesia bovis
          Length = 339

 Score = 49.6 bits (113), Expect = 8e-05
 Identities = 25/73 (34%), Positives = 41/73 (56%)
 Frame = +1

Query: 289 GVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSAS 468
           G+  G   V   ++ E  V++ + I G ++ IIQ+ +  VN N++ELL M  A + S A 
Sbjct: 55  GLTLGKSDVSTFSDGEIKVDLQEEILGCDVVIIQSTSPPVNRNLIELLFMISAARKSGAK 114

Query: 469 SIVGVIPYLPYSK 507
            I  +IPY  Y++
Sbjct: 115 QITAIIPYFGYAR 127


>UniRef50_Q9EWS0 Cluster: Putative ribose-phosphate
           pyrophosphokinase; n=9; Actinomycetales|Rep: Putative
           ribose-phosphate pyrophosphokinase - Streptomyces
           coelicolor
          Length = 317

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 21/69 (30%), Positives = 41/69 (59%)
 Frame = +3

Query: 543 KLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIPDYRNSVIVA 722
           +L+A ++  +G S ++ M LH  ++ GFF  PVD+L A   L  + ++   D   + +V+
Sbjct: 110 RLVADLLVAAGASRVLAMTLHSPQVHGFFSVPVDHLHALRELAAHFRQY--DLSRATVVS 167

Query: 723 RNPGSAKKS 749
            + G+AK++
Sbjct: 168 PDLGNAKEA 176



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 25/93 (26%), Positives = 48/93 (51%)
 Frame = +1

Query: 238 FEWKLTPELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNN 417
           F     P+LA+ +  +LGV      V    N    V++  + R ++++++Q     V  +
Sbjct: 7   FSGSAHPDLAEEVCAQLGVPLSPTRVSRFANDCLEVQLMANCRERDVFLVQPLVTPVQEH 66

Query: 418 IMELLIMAYACKTSSASSIVGVIPYLPYSKHAK 516
           ++ELL+M  A + +SA  I  V+P+  Y++  K
Sbjct: 67  LVELLMMCDAARGASAGRITVVMPHYSYARSDK 99


>UniRef50_Q4DSS9 Cluster: Ribose-phosphate pyrophosphokinase,
           putative; n=3; Trypanosoma|Rep: Ribose-phosphate
           pyrophosphokinase, putative - Trypanosoma cruzi
          Length = 705

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 20/75 (26%), Positives = 45/75 (60%), Gaps = 5/75 (6%)
 Frame = +3

Query: 546 LLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRAS----PFLLQYIQESIPDYRNSV 713
           ++A+++ K G  H+IT+D+  ++++G F  P++N+ A      F+ +++     D+RN  
Sbjct: 377 VVAELLEKMGCQHVITVDMSSEQVEGMFSVPLENISARYEFVRFIAKHLTNEGHDFRNIT 436

Query: 714 IVARNPGSAKKS-YF 755
           +V+ +  S  ++ YF
Sbjct: 437 VVSPSGTSVSRAKYF 451



 Score = 39.1 bits (87), Expect = 0.12
 Identities = 20/65 (30%), Positives = 37/65 (56%), Gaps = 6/65 (9%)
 Frame = +1

Query: 328 NRETIVEIADSIRGKNIYIIQTGTK------DVNNNIMELLIMAYACKTSSASSIVGVIP 489
           N E  V ++ ++RG +++++Q+  +        +   MEL +M +  + SSA+ I  VIP
Sbjct: 305 NGEINVSLSRTLRGDDVFVLQSLVRCDHLGLSHSGTFMELALMLHTARLSSAARITAVIP 364

Query: 490 YLPYS 504
           YL Y+
Sbjct: 365 YLAYA 369


>UniRef50_UPI00015BACA3 Cluster: ribose-phosphate pyrophosphokinase;
           n=1; Ignicoccus hospitalis KIN4/I|Rep: ribose-phosphate
           pyrophosphokinase - Ignicoccus hospitalis KIN4/I
          Length = 298

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 17/58 (29%), Positives = 35/58 (60%)
 Frame = +1

Query: 334 ETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSK 507
           E+ V I   + G+++ ++ TG  D N+ ++E+L+     K   A S+  ++PY+PY++
Sbjct: 37  ESYVRIPIPVSGEDVLVVHTGFPDQNDRVIEVLLTIDTLKDLGAESVTLLMPYMPYAR 94


>UniRef50_A2X0F3 Cluster: Ribose-phosphate pyrophosphokinase; n=2;
           Oryza sativa|Rep: Ribose-phosphate pyrophosphokinase -
           Oryza sativa subsp. indica (Rice)
          Length = 330

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 17/46 (36%), Positives = 30/46 (65%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNL 650
           K + R  I +KL+A M+ ++G + ++  DLH  +  G+FD PVD++
Sbjct: 150 KSQGRESIAAKLVANMITEAGANRVLVCDLHSSQAMGYFDIPVDHV 195


>UniRef50_O62580 Cluster: Phosphoribosyl pyrophosphate synthetase;
           n=2; Giardia intestinalis|Rep: Phosphoribosyl
           pyrophosphate synthetase - Giardia lamblia (Giardia
           intestinalis)
          Length = 370

 Score = 43.2 bits (97), Expect = 0.007
 Identities = 23/81 (28%), Positives = 42/81 (51%), Gaps = 3/81 (3%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFF--DCPVDNLRASPFLLQYIQE 686
           K   R  I +KL+  ++  SG+  ++  D+H  +IQGFF    P D++      +Q I +
Sbjct: 109 KAASRTPISAKLVTDLLIASGVDRVVVQDIHAAQIQGFFPSSIPFDHIDGYLVFIQAIID 168

Query: 687 SI-PDYRNSVIVARNPGSAKK 746
               D +N ++V+ + G A +
Sbjct: 169 RFEEDIKNLIVVSPDAGGATR 189



 Score = 38.7 bits (86), Expect = 0.16
 Identities = 19/59 (32%), Positives = 35/59 (59%), Gaps = 1/59 (1%)
 Frame = +1

Query: 334 ETIVEIADSIRGKNIYIIQTGTKD-VNNNIMELLIMAYACKTSSASSIVGVIPYLPYSK 507
           E  ++   +IRG +++I+        N+N+MELL+   A K +SA+ +  +IPY  Y++
Sbjct: 47  EINLQYESNIRGCDLFIVGAICPPRCNDNLMELLLAIDAAKRASAAHVTAIIPYFGYAR 105


>UniRef50_Q660Y0 Cluster: Phosphoribosyl pyrophosphate synthetase;
           n=3; Borrelia burgdorferi group|Rep: Phosphoribosyl
           pyrophosphate synthetase - Borrelia garinii
          Length = 406

 Score = 42.7 bits (96), Expect = 0.010
 Identities = 25/84 (29%), Positives = 47/84 (55%), Gaps = 3/84 (3%)
 Frame = +3

Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFF-DCPVDNLRASPFLLQYIQES 689
           K   R C+ + L+ + + + G+ HI+T+D+H K I+  F     +NL  S  + + + + 
Sbjct: 166 KKHSRECLTASLIGRFLEELGIRHILTLDIHSKAIENVFRKVYFENLNVSYEIFKSLGDL 225

Query: 690 IPDYRNS--VIVARNPGSAKKSYF 755
           I D R+S  VIV+ + G+  ++ F
Sbjct: 226 I-DIRDSNLVIVSPDTGAVSRNKF 248



 Score = 35.9 bits (79), Expect = 1.1
 Identities = 26/77 (33%), Positives = 39/77 (50%), Gaps = 14/77 (18%)
 Frame = +1

Query: 328 NRETIVEIADSIRGKNIYIIQ--TGTKDV------------NNNIMELLIMAYACKTSSA 465
           N E   EI  +IR K+I+I+Q    T +V            N++IM L+    AC  + A
Sbjct: 90  NGEFKTEILKTIRNKDIFIVQDVANTYEVEINSSEKIIMTVNDHIMNLMTTIDACMQAKA 149

Query: 466 SSIVGVIPYLPYSKHAK 516
           +S+  +IP  PYS+  K
Sbjct: 150 NSVSVIIPSYPYSRQDK 166


>UniRef50_Q0U4M2 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 89

 Score = 42.7 bits (96), Expect = 0.010
 Identities = 21/59 (35%), Positives = 35/59 (59%)
 Frame = +1

Query: 226 GHCYFEWKLTPELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTK 402
           G   F     P+L + I +RLG ++G  ++    N ET V I  SIR K+++I+Q+G++
Sbjct: 25  GAIVFAGSSHPKLVEGICDRLGTKQGSATLGKFKNGETSVTIHTSIRNKDVFIVQSGSE 83


>UniRef50_Q8KKS6 Cluster: Ribose-phosphate pyrophosphokinase
           protein; n=1; Rhizobium etli CFN 42|Rep:
           Ribose-phosphate pyrophosphokinase protein - Rhizobium
           etli (strain CFN 42 / ATCC 51251)
          Length = 313

 Score = 41.5 bits (93), Expect = 0.022
 Identities = 21/74 (28%), Positives = 44/74 (59%)
 Frame = +3

Query: 528 GCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIPDYRN 707
           G +  ++LA ++   G+  +IT +LH  ++   F CPV NL+ +P L++++  +  D   
Sbjct: 118 GPVPVRILAGIIETLGIDRLITFELHVPQLCAAFACPVVNLQFAPALVRHLGSAAVD--G 175

Query: 708 SVIVARNPGSAKKS 749
            ++V+ + G AK++
Sbjct: 176 DMVVSPDFGGAKRA 189



 Score = 41.1 bits (92), Expect = 0.029
 Identities = 19/61 (31%), Positives = 32/61 (52%)
 Frame = +1

Query: 325 TNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYS 504
           +N +  V   D   G N+ ++QT    V++ + EL +   A +     +I  V+PYLPYS
Sbjct: 49  SNGQMAVTPRDGGLGGNVVVVQTFPDSVHDRLFELFLALGAVRARGPRTITAVLPYLPYS 108

Query: 505 K 507
           +
Sbjct: 109 R 109


>UniRef50_A4CGY8 Cluster: Phosphoribosylpyrophosphate synthetase;
           n=1; Robiginitalea biformata HTCC2501|Rep:
           Phosphoribosylpyrophosphate synthetase - Robiginitalea
           biformata HTCC2501
          Length = 297

 Score = 41.1 bits (92), Expect = 0.029
 Identities = 21/90 (23%), Positives = 44/90 (48%)
 Frame = +1

Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
           EL +L+A ++    G C++    + E+   I   ++GK + ++ T   + +  ++ L  +
Sbjct: 13  ELTELLAKKMNAEIGECAIRKFPDGESYTRILSDVKGKCVVLVCT-LHEPDVKLLPLYFL 71

Query: 439 AYACKTSSASSIVGVIPYLPYSKHAKCGNE 528
           ++  K+  A     V PYL Y +  K  N+
Sbjct: 72  SHTAKSLGAMCTCLVAPYLAYMRQDKVFND 101


>UniRef50_Q97Z86 Cluster: Ribose-phosphate pyrophosphokinase; n=5;
           Sulfolobaceae|Rep: Ribose-phosphate pyrophosphokinase -
           Sulfolobus solfataricus
          Length = 291

 Score = 40.7 bits (91), Expect = 0.038
 Identities = 15/58 (25%), Positives = 33/58 (56%)
 Frame = +1

Query: 334 ETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSK 507
           E+ + +  SIR + + ++QT     + +++EL ++A   +   A  +  ++PYL YS+
Sbjct: 36  ESYIRVPSSIRDEEVLLVQTTDYPQDKHLIELFLIAETIRDLGAKKLTAIVPYLAYSR 93


>UniRef50_A2XQT7 Cluster: Putative uncharacterized protein; n=1;
           Oryza sativa (indica cultivar-group)|Rep: Putative
           uncharacterized protein - Oryza sativa subsp. indica
           (Rice)
          Length = 165

 Score = 39.9 bits (89), Expect = 0.067
 Identities = 19/41 (46%), Positives = 29/41 (70%)
 Frame = +1

Query: 361 IRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGV 483
           +RG +++++Q  T  VN N+M+LLIM  AC  +SA+SI  V
Sbjct: 85  LRGYDVFLVQP-TCPVNENLMDLLIMTDACMRASANSITAV 124


>UniRef50_Q4QIB8 Cluster: Ribose-phosphate pyrophosphokinase,
           putative; n=3; Leishmania|Rep: Ribose-phosphate
           pyrophosphokinase, putative - Leishmania major
          Length = 836

 Score = 38.7 bits (86), Expect = 0.16
 Identities = 15/54 (27%), Positives = 31/54 (57%)
 Frame = +3

Query: 549 LAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIPDYRNS 710
           +A+M+   G  H+IT+D+H  +++G F  P+++  A    ++YI   +    N+
Sbjct: 444 VAEMIELVGCHHVITVDMHSDQVEGMFSIPIESASAMYEFVRYISNLLESEGNT 497



 Score = 37.9 bits (84), Expect = 0.27
 Identities = 18/67 (26%), Positives = 42/67 (62%), Gaps = 6/67 (8%)
 Frame = +1

Query: 328 NRETIVEIADSIRGKNIYIIQT----GTKDVNNN--IMELLIMAYACKTSSASSIVGVIP 489
           N E  V +   +RG +++++Q+     +++++N   +MEL ++ ++ + ++A+ I  VIP
Sbjct: 371 NGEVSVNLQAPVRGDDVFVVQSMVALESENLSNAGALMELALLVHSAQLAAAARITAVIP 430

Query: 490 YLPYSKH 510
           YL Y+ +
Sbjct: 431 YLAYTSN 437


>UniRef50_Q3YQZ8 Cluster: Ribose-phosphate pyrophospho kinase; n=1;
           Ehrlichia canis str. Jake|Rep: Ribose-phosphate
           pyrophospho kinase - Ehrlichia canis (strain Jake)
          Length = 318

 Score = 37.9 bits (84), Expect = 0.27
 Identities = 19/70 (27%), Positives = 39/70 (55%)
 Frame = +3

Query: 540 SKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIPDYRNSVIV 719
           +K++   +  + +++II +DLH  ++ GFFD  + NL +    ++ I     D  N VIV
Sbjct: 117 AKVIINTLETANINNIIFIDLHSNQLTGFFDTSITNLSSHAIFIEDIAGKY-DMDNLVIV 175

Query: 720 ARNPGSAKKS 749
           + + G+  ++
Sbjct: 176 SPDYGALNRT 185


>UniRef50_A4BQ39 Cluster: Ribose-phosphate pyrophosphokinase; n=9;
           Proteobacteria|Rep: Ribose-phosphate pyrophosphokinase -
           Nitrococcus mobilis Nb-231
          Length = 362

 Score = 37.9 bits (84), Expect = 0.27
 Identities = 16/55 (29%), Positives = 33/55 (60%), Gaps = 4/55 (7%)
 Frame = +1

Query: 355 DSIRGKNIYII----QTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSK 507
           + +RG+++Y++    Q  ++ VN+ ++ LL    A + + A  +  VIPYL Y++
Sbjct: 78  EGVRGRDVYVLHSLYQDASEGVNDKLVRLLFFLGALRDAHAGCLTAVIPYLAYAR 132


>UniRef50_O26877 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
           Methanobacteriaceae|Rep: Ribose-phosphate
           pyrophosphokinase - Methanobacterium thermoautotrophicum
          Length = 285

 Score = 37.9 bits (84), Expect = 0.27
 Identities = 21/68 (30%), Positives = 40/68 (58%)
 Frame = +3

Query: 534 IVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIPDYRNSV 713
           + +K++A ++  +G   I+T++LH+  +  FF  PV  L A P + ++I  S  D  + V
Sbjct: 102 VSAKIVAHLLEAAGADEIVTVNLHENCLSEFFRVPVRELSAMPLIAEHI--SFLD--DPV 157

Query: 714 IVARNPGS 737
           I+A + G+
Sbjct: 158 IIAPDKGA 165


>UniRef50_O83317 Cluster: Phosphoribosyl pyrophosphate synthetase;
           n=2; Treponema|Rep: Phosphoribosyl pyrophosphate
           synthetase - Treponema pallidum
          Length = 421

 Score = 37.5 bits (83), Expect = 0.36
 Identities = 25/79 (31%), Positives = 46/79 (58%), Gaps = 5/79 (6%)
 Frame = +3

Query: 534 IVSKLLAQMMCKSGLSHIITMDLHQKEIQ-GFFDCPVDNLRASPFLLQYIQE----SIPD 698
           + + LL  +    G+SHI+T+DLH +EI+  F    ++NL AS  +++ + +    S PD
Sbjct: 178 LTAGLLGSVYEYLGVSHIVTLDLHSREIENAFHRTRLENLHASYQIIRELAKIENLSDPD 237

Query: 699 YRNSVIVARNPGSAKKSYF 755
               V+VA + G+ +++ F
Sbjct: 238 I-PFVVVAPDSGAVERNKF 255



 Score = 37.1 bits (82), Expect = 0.47
 Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 16/83 (19%)
 Frame = +1

Query: 328 NRETIVEIADSIRGKNIYIIQ-----------TGTK----DVNNNIMELLIMAYACKTSS 462
           N E   +I + IRGK+++I Q            G       VN+++M L++   A + + 
Sbjct: 94  NGELKTQINECIRGKDVFIFQDVENHQPVLVNNGKSKKIFSVNDHVMMLIVTIDAVRHAG 153

Query: 463 ASSIVGVIPYLPYSK-HAKCGNE 528
           A  +  V+P  PYS+ H KCG E
Sbjct: 154 AGRVTLVLPTYPYSRQHKKCGRE 176


>UniRef50_Q0W4S8 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
           uncultured methanogenic archaeon RC-I|Rep:
           Ribose-phosphate pyrophosphokinase - Uncultured
           methanogenic archaeon RC-I
          Length = 298

 Score = 37.5 bits (83), Expect = 0.36
 Identities = 22/84 (26%), Positives = 39/84 (46%)
 Frame = +1

Query: 256 PELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLI 435
           P LA  IA R+G +    S+    + E  V   D    + +  +QT     N+ ++E+++
Sbjct: 12  PGLAKSIARRMGTKAHFPSIEKFPDGEIHVVEGDYTPAQTVVYVQTMHPHPNDMLVEMML 71

Query: 436 MAYACKTSSASSIVGVIPYLPYSK 507
                K   A  ++ VIPY+ Y +
Sbjct: 72  TVDLLKELGAERVIAVIPYVGYMR 95


>UniRef50_Q2GCV8 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
           Neorickettsia sennetsu str. Miyayama|Rep:
           Ribose-phosphate pyrophosphokinase - Neorickettsia
           sennetsu (strain Miyayama)
          Length = 305

 Score = 36.3 bits (80), Expect = 0.83
 Identities = 22/71 (30%), Positives = 44/71 (61%)
 Frame = +3

Query: 534 IVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIPDYRNSV 713
           I +K++A+++ +  +S +  +D+H  + +GFF+ PV N+   P+ L  ++ES+    N  
Sbjct: 104 ISAKVVARLIGER-ISLLFVLDVHFPQFEGFFEIPVYNI--LPWTL--LKESVHVGHNMA 158

Query: 714 IVARNPGSAKK 746
           +VA + G+ KK
Sbjct: 159 LVAPDVGAVKK 169


>UniRef50_A4WYL1 Cluster: Putative uncharacterized protein; n=1;
           Rhodobacter sphaeroides ATCC 17025|Rep: Putative
           uncharacterized protein - Rhodobacter sphaeroides ATCC
           17025
          Length = 347

 Score = 36.3 bits (80), Expect = 0.83
 Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 4/95 (4%)
 Frame = +1

Query: 235 YFEWKLTPELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIY---IIQTG-TK 402
           YF+   +  L   +A R G+          +  E  +    S+RG  +    ++  G   
Sbjct: 28  YFDLTPSHPLGHAVARRAGLSVAMHEARAFSGGEHKLRPLVSVRGHEVCLFSVLHAGEVG 87

Query: 403 DVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSK 507
            VN+ ++ LL+ A  C+T+ A+ ++ V P+LPY +
Sbjct: 88  SVNDALVRLLLFAACCRTNGAARVLIVSPWLPYMR 122


>UniRef50_Q8ZU24 Cluster: Ribose-phosphate pyrophosphokinase; n=4;
           Pyrobaculum|Rep: Ribose-phosphate pyrophosphokinase -
           Pyrobaculum aerophilum
          Length = 284

 Score = 35.5 bits (78), Expect = 1.4
 Identities = 18/58 (31%), Positives = 36/58 (62%)
 Frame = +1

Query: 334 ETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSK 507
           E +V + ++ RG+ + ++      VN+N+++L +   A   + AS I+ VIPY+PY++
Sbjct: 33  EVLVRLPEA-RGE-VAVVARLYPAVNDNLIKLFLTIDALNDAGASKIILVIPYMPYAR 88


>UniRef50_Q9F9G7 Cluster: Cwp66; n=19; Clostridium difficile|Rep:
           Cwp66 - Clostridium difficile
          Length = 610

 Score = 33.9 bits (74), Expect = 4.4
 Identities = 19/53 (35%), Positives = 27/53 (50%)
 Frame = +1

Query: 322 KTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVG 480
           +TN + I E       KNIY+ + GTK+ N+ I  L +   A K SS   + G
Sbjct: 237 ETNAKIIEEFYKDTDIKNIYVTKDGTKNKNDLIDSLAVGVLAAKNSSPIVLAG 289


>UniRef50_A1HDW3 Cluster: Ribose-phosphate diphosphokinase; n=3;
           Ralstonia|Rep: Ribose-phosphate diphosphokinase -
           Ralstonia pickettii 12J
          Length = 313

 Score = 33.1 bits (72), Expect = 7.7
 Identities = 20/78 (25%), Positives = 36/78 (46%)
 Frame = +1

Query: 274 IANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACK 453
           +A  L    G  +V H  + E+ V +   + G  + I+ T     +  ++ LL +A A +
Sbjct: 27  LAIPLRAELGHAAVTHFPDGESYVRLYTPVHGAEVAIVCT-LDHPDEKLLPLLWLAIAAR 85

Query: 454 TSSASSIVGVIPYLPYSK 507
              A  +  + PYLPY +
Sbjct: 86  QGGARRVGLIAPYLPYMR 103


>UniRef50_Q8TUT6 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
           Methanopyrus kandleri|Rep: Ribose-phosphate
           pyrophosphokinase - Methanopyrus kandleri
          Length = 291

 Score = 33.1 bits (72), Expect = 7.7
 Identities = 12/58 (20%), Positives = 32/58 (55%)
 Frame = +1

Query: 334 ETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSK 507
           E IV +   + G  + ++ + +   + N+++ +I   A + + A  ++ ++PY+ YS+
Sbjct: 36  EQIVRVPPELDG-TVVVVHSMSPPQDENLVKAIITLDAARENGAEEVIAIVPYMAYSR 92


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 780,025,391
Number of Sequences: 1657284
Number of extensions: 16157241
Number of successful extensions: 35616
Number of sequences better than 10.0: 98
Number of HSP's better than 10.0 without gapping: 34456
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 35597
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 63381147830
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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