Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= e40h0372
(762 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR457082-1|CAG33363.1| 369|Homo sapiens PRPSAP2 protein. 146 1e-34
BC106050-1|AAI06051.1| 369|Homo sapiens phosphoribosyl pyrophos... 146 1e-34
BC101672-1|AAI01673.1| 369|Homo sapiens phosphoribosyl pyrophos... 146 1e-34
BC101670-1|AAI01671.1| 369|Homo sapiens phosphoribosyl pyrophos... 146 1e-34
AB007851-1|BAA25435.1| 369|Homo sapiens 41-kDa phosphoribosylpy... 146 1e-34
D61391-1|BAA09612.1| 356|Homo sapiens phosphoribosypyrophosphat... 132 2e-30
BC009012-1|AAH09012.1| 356|Homo sapiens phosphoribosyl pyrophos... 132 2e-30
M57423-1|AAB59463.1| 318|Homo sapiens phosphoribosylpyrophospha... 89 2e-17
BC062797-1|AAH62797.2| 318|Homo sapiens phosphoribosyl pyrophos... 89 2e-17
X15331-1|CAA33386.1| 318|Homo sapiens protein ( Human mRNA for ... 89 2e-17
D00860-1|BAA00733.1| 318|Homo sapiens phosphoribosyl pyrophosph... 89 2e-17
BC001605-1|AAH01605.1| 318|Homo sapiens phosphoribosyl pyrophos... 89 2e-17
AL772400-2|CAI41098.1| 318|Homo sapiens phosphoribosyl pyrophos... 89 2e-17
AL772400-1|CAI41097.1| 168|Homo sapiens phosphoribosyl pyrophos... 89 2e-17
AL137787-2|CAI42173.1| 318|Homo sapiens phosphoribosyl pyrophos... 89 2e-17
AL137787-1|CAI42172.1| 168|Homo sapiens phosphoribosyl pyrophos... 89 2e-17
AK223169-1|BAD96889.1| 318|Homo sapiens phosphoribosyl pyrophos... 89 2e-17
Y00971-1|CAA68785.1| 318|Homo sapiens protein ( Human mRNA for ... 88 4e-17
BC119663-1|AAI19664.1| 318|Homo sapiens phosphoribosyl pyrophos... 88 4e-17
BC110875-1|AAI10876.2| 318|Homo sapiens phosphoribosyl pyrophos... 88 4e-17
BC040483-1|AAH40483.3| 318|Homo sapiens phosphoribosyl pyrophos... 88 4e-17
BC030019-1|AAH30019.2| 346|Homo sapiens PRPS2 protein protein. 88 4e-17
BC119662-1|AAI19663.1| 321|Homo sapiens phosphoribosyl pyrophos... 87 6e-17
AL772400-3|CAI41099.1| 218|Homo sapiens phosphoribosyl pyrophos... 53 1e-06
AL137787-3|CAI42174.1| 218|Homo sapiens phosphoribosyl pyrophos... 53 1e-06
AK130921-1|BAC85460.1| 572|Homo sapiens protein ( Homo sapiens ... 33 0.84
>CR457082-1|CAG33363.1| 369|Homo sapiens PRPSAP2 protein.
Length = 369
Score = 146 bits (353), Expect = 1e-34
Identities = 66/80 (82%), Positives = 75/80 (93%)
Frame = +3
Query: 510 CKMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQES 689
CKMRKRG IVSKLLA MMCK+GL+H+ITMDLHQKEIQGFF+ PVDNLRASPFLLQYIQE
Sbjct: 117 CKMRKRGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEE 176
Query: 690 IPDYRNSVIVARNPGSAKKS 749
IPDYRN+VIVA++P SAK++
Sbjct: 177 IPDYRNAVIVAKSPASAKRA 196
Score = 116 bits (278), Expect = 1e-25
Identities = 55/86 (63%), Positives = 65/86 (75%)
Frame = +1
Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
EL+ IA RLGV G VY + NRET V+I +S+RGK+++IIQT +KDVN IMELLIM
Sbjct: 33 ELSKKIAERLGVEMGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIM 92
Query: 439 AYACKTSSASSIVGVIPYLPYSKHAK 516
YACKTS A SI+GVIPY PYSK K
Sbjct: 93 VYACKTSCAKSIIGVIPYFPYSKQCK 118
>BC106050-1|AAI06051.1| 369|Homo sapiens phosphoribosyl
pyrophosphate synthetase-associated protein 2 protein.
Length = 369
Score = 146 bits (353), Expect = 1e-34
Identities = 66/80 (82%), Positives = 75/80 (93%)
Frame = +3
Query: 510 CKMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQES 689
CKMRKRG IVSKLLA MMCK+GL+H+ITMDLHQKEIQGFF+ PVDNLRASPFLLQYIQE
Sbjct: 117 CKMRKRGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEE 176
Query: 690 IPDYRNSVIVARNPGSAKKS 749
IPDYRN+VIVA++P SAK++
Sbjct: 177 IPDYRNAVIVAKSPASAKRA 196
Score = 116 bits (278), Expect = 1e-25
Identities = 55/86 (63%), Positives = 65/86 (75%)
Frame = +1
Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
EL+ IA RLGV G VY + NRET V+I +S+RGK+++IIQT +KDVN IMELLIM
Sbjct: 33 ELSKKIAERLGVEMGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIM 92
Query: 439 AYACKTSSASSIVGVIPYLPYSKHAK 516
YACKTS A SI+GVIPY PYSK K
Sbjct: 93 VYACKTSCAKSIIGVIPYFPYSKQCK 118
>BC101672-1|AAI01673.1| 369|Homo sapiens phosphoribosyl
pyrophosphate synthetase-associated protein 2 protein.
Length = 369
Score = 146 bits (353), Expect = 1e-34
Identities = 66/80 (82%), Positives = 75/80 (93%)
Frame = +3
Query: 510 CKMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQES 689
CKMRKRG IVSKLLA MMCK+GL+H+ITMDLHQKEIQGFF+ PVDNLRASPFLLQYIQE
Sbjct: 117 CKMRKRGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEE 176
Query: 690 IPDYRNSVIVARNPGSAKKS 749
IPDYRN+VIVA++P SAK++
Sbjct: 177 IPDYRNAVIVAKSPASAKRA 196
Score = 116 bits (278), Expect = 1e-25
Identities = 55/86 (63%), Positives = 65/86 (75%)
Frame = +1
Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
EL+ IA RLGV G VY + NRET V+I +S+RGK+++IIQT +KDVN IMELLIM
Sbjct: 33 ELSKKIAERLGVEMGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIM 92
Query: 439 AYACKTSSASSIVGVIPYLPYSKHAK 516
YACKTS A SI+GVIPY PYSK K
Sbjct: 93 VYACKTSCAKSIIGVIPYFPYSKQCK 118
>BC101670-1|AAI01671.1| 369|Homo sapiens phosphoribosyl
pyrophosphate synthetase-associated protein 2 protein.
Length = 369
Score = 146 bits (353), Expect = 1e-34
Identities = 66/80 (82%), Positives = 75/80 (93%)
Frame = +3
Query: 510 CKMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQES 689
CKMRKRG IVSKLLA MMCK+GL+H+ITMDLHQKEIQGFF+ PVDNLRASPFLLQYIQE
Sbjct: 117 CKMRKRGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEE 176
Query: 690 IPDYRNSVIVARNPGSAKKS 749
IPDYRN+VIVA++P SAK++
Sbjct: 177 IPDYRNAVIVAKSPASAKRA 196
Score = 116 bits (278), Expect = 1e-25
Identities = 55/86 (63%), Positives = 65/86 (75%)
Frame = +1
Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
EL+ IA RLGV G VY + NRET V+I +S+RGK+++IIQT +KDVN IMELLIM
Sbjct: 33 ELSKKIAERLGVEMGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIM 92
Query: 439 AYACKTSSASSIVGVIPYLPYSKHAK 516
YACKTS A SI+GVIPY PYSK K
Sbjct: 93 VYACKTSCAKSIIGVIPYFPYSKQCK 118
>AB007851-1|BAA25435.1| 369|Homo sapiens 41-kDa
phosphoribosylpyrophosphate synthetase-associated
protein protein.
Length = 369
Score = 146 bits (353), Expect = 1e-34
Identities = 66/80 (82%), Positives = 75/80 (93%)
Frame = +3
Query: 510 CKMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQES 689
CKMRKRG IVSKLLA MMCK+GL+H+ITMDLHQKEIQGFF+ PVDNLRASPFLLQYIQE
Sbjct: 117 CKMRKRGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEE 176
Query: 690 IPDYRNSVIVARNPGSAKKS 749
IPDYRN+VIVA++P SAK++
Sbjct: 177 IPDYRNAVIVAKSPASAKRA 196
Score = 116 bits (278), Expect = 1e-25
Identities = 55/86 (63%), Positives = 65/86 (75%)
Frame = +1
Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
EL+ IA RLGV G VY + NRET V+I +S+RGK+++IIQT +KDVN IMELLIM
Sbjct: 33 ELSKKIAERLGVEMGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIM 92
Query: 439 AYACKTSSASSIVGVIPYLPYSKHAK 516
YACKTS A SI+GVIPY PYSK K
Sbjct: 93 VYACKTSCAKSIIGVIPYFPYSKQCK 118
>D61391-1|BAA09612.1| 356|Homo sapiens phosphoribosypyrophosphate
synthetase-associated protein 39 protein.
Length = 356
Score = 132 bits (318), Expect = 2e-30
Identities = 61/79 (77%), Positives = 71/79 (89%)
Frame = +3
Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
KMRKRG IV KLLA M+ K+GL+HIITMDLHQKEIQGFF PVDNLRASPFLLQYIQE I
Sbjct: 106 KMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEI 165
Query: 693 PDYRNSVIVARNPGSAKKS 749
P+YRN+VIVA++P +AK++
Sbjct: 166 PNYRNAVIVAKSPDAAKRA 184
Score = 101 bits (242), Expect = 3e-21
Identities = 50/86 (58%), Positives = 62/86 (72%)
Frame = +1
Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
ELA I RLG G VY +TN ET VEI + +RG++I+IIQT +DVN +MELLIM
Sbjct: 21 ELAKRITERLGAELGKSVVYQETNGETRVEIKEFVRGQDIFIIQTIPRDVNTAVMELLIM 80
Query: 439 AYACKTSSASSIVGVIPYLPYSKHAK 516
AYA KT+ A +I+GVIPY PYSK +K
Sbjct: 81 AYALKTACARNIIGVIPYFPYSKQSK 106
>BC009012-1|AAH09012.1| 356|Homo sapiens phosphoribosyl
pyrophosphate synthetase-associated protein 1 protein.
Length = 356
Score = 132 bits (318), Expect = 2e-30
Identities = 61/79 (77%), Positives = 71/79 (89%)
Frame = +3
Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
KMRKRG IV KLLA M+ K+GL+HIITMDLHQKEIQGFF PVDNLRASPFLLQYIQE I
Sbjct: 106 KMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEI 165
Query: 693 PDYRNSVIVARNPGSAKKS 749
P+YRN+VIVA++P +AK++
Sbjct: 166 PNYRNAVIVAKSPDAAKRA 184
Score = 103 bits (248), Expect = 5e-22
Identities = 51/86 (59%), Positives = 63/86 (73%)
Frame = +1
Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
ELA I RLG G VY +TN ET VEI +S+RG++I+IIQT +DVN +MELLIM
Sbjct: 21 ELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIM 80
Query: 439 AYACKTSSASSIVGVIPYLPYSKHAK 516
AYA KT+ A +I+GVIPY PYSK +K
Sbjct: 81 AYALKTACARNIIGVIPYFPYSKQSK 106
>M57423-1|AAB59463.1| 318|Homo sapiens phosphoribosylpyrophosphate
synthetase subunit III protein.
Length = 318
Score = 89.0 bits (211), Expect = 2e-17
Identities = 40/78 (51%), Positives = 58/78 (74%)
Frame = +3
Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
K + R I +KL+A M+ +G HIITMDLH +IQGFFD PVDNL A P +L++I+E+I
Sbjct: 100 KDKSRSPISAKLVANMLSIAGADHIITMDLHASQIQGFFDIPVDNLYAEPTVLKWIRENI 159
Query: 693 PDYRNSVIVARNPGSAKK 746
P+++N +IV+ + G AK+
Sbjct: 160 PEWKNCIIVSPDAGGAKR 177
Score = 85.8 bits (203), Expect = 1e-16
Identities = 39/86 (45%), Positives = 61/86 (70%)
Frame = +1
Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
+L+ IA+RLG+ G +N+ET VEI +S+RG+++YI+Q+G ++N+++MELLIM
Sbjct: 14 DLSQKIADRLGLELGKVVTKKFSNQETCVEIDESVRGEDVYIVQSGCGEINDSLMELLIM 73
Query: 439 AYACKTSSASSIVGVIPYLPYSKHAK 516
ACK +SAS + VIP PY++ K
Sbjct: 74 INACKIASASRVTAVIPCFPYARQDK 99
>BC062797-1|AAH62797.2| 318|Homo sapiens phosphoribosyl
pyrophosphate synthetase 1-like 1 protein.
Length = 318
Score = 89.0 bits (211), Expect = 2e-17
Identities = 40/78 (51%), Positives = 58/78 (74%)
Frame = +3
Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
K + R I +KL+A M+ +G HIITMDLH +IQGFFD PVDNL A P +L++I+E+I
Sbjct: 100 KDKSRSPISAKLVANMLSIAGADHIITMDLHASQIQGFFDIPVDNLYAEPTVLKWIRENI 159
Query: 693 PDYRNSVIVARNPGSAKK 746
P+++N +IV+ + G AK+
Sbjct: 160 PEWKNCIIVSPDAGGAKR 177
Score = 85.8 bits (203), Expect = 1e-16
Identities = 39/86 (45%), Positives = 61/86 (70%)
Frame = +1
Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
+L+ IA+RLG+ G +N+ET VEI +S+RG+++YI+Q+G ++N+++MELLIM
Sbjct: 14 DLSQKIADRLGLELGKVVTKKFSNQETCVEIDESVRGEDVYIVQSGCGEINDSLMELLIM 73
Query: 439 AYACKTSSASSIVGVIPYLPYSKHAK 516
ACK +SAS + VIP PY++ K
Sbjct: 74 INACKIASASRVTAVIPCFPYARQDK 99
>X15331-1|CAA33386.1| 318|Homo sapiens protein ( Human mRNA for
phosphoribosylpyrophosphate synthetase subunit one. ).
Length = 318
Score = 88.6 bits (210), Expect = 2e-17
Identities = 40/86 (46%), Positives = 61/86 (70%)
Frame = +1
Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
+L+ IA+RLG+ G +N+ET VEI +S+RG+++YI+Q+G ++N+N+MELLIM
Sbjct: 14 DLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIM 73
Query: 439 AYACKTSSASSIVGVIPYLPYSKHAK 516
ACK +SAS + VIP PY++ K
Sbjct: 74 INACKIASASRVTAVIPCFPYARQDK 99
Score = 86.2 bits (204), Expect = 1e-16
Identities = 40/78 (51%), Positives = 56/78 (71%)
Frame = +3
Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
K + R I +KL+A M+ +G HIITMDLH +IQGFFD PVDNL A P +L++I+E+I
Sbjct: 100 KDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENI 159
Query: 693 PDYRNSVIVARNPGSAKK 746
++RN IV+ + G AK+
Sbjct: 160 SEWRNCTIVSPDAGGAKR 177
>D00860-1|BAA00733.1| 318|Homo sapiens phosphoribosyl pyrophosphate
synthetase subunit I protein.
Length = 318
Score = 88.6 bits (210), Expect = 2e-17
Identities = 40/86 (46%), Positives = 61/86 (70%)
Frame = +1
Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
+L+ IA+RLG+ G +N+ET VEI +S+RG+++YI+Q+G ++N+N+MELLIM
Sbjct: 14 DLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIM 73
Query: 439 AYACKTSSASSIVGVIPYLPYSKHAK 516
ACK +SAS + VIP PY++ K
Sbjct: 74 INACKIASASRVTAVIPCFPYARQDK 99
Score = 86.2 bits (204), Expect = 1e-16
Identities = 40/78 (51%), Positives = 56/78 (71%)
Frame = +3
Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
K + R I +KL+A M+ +G HIITMDLH +IQGFFD PVDNL A P +L++I+E+I
Sbjct: 100 KDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENI 159
Query: 693 PDYRNSVIVARNPGSAKK 746
++RN IV+ + G AK+
Sbjct: 160 SEWRNCTIVSPDAGGAKR 177
>BC001605-1|AAH01605.1| 318|Homo sapiens phosphoribosyl
pyrophosphate synthetase 1 protein.
Length = 318
Score = 88.6 bits (210), Expect = 2e-17
Identities = 40/86 (46%), Positives = 61/86 (70%)
Frame = +1
Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
+L+ IA+RLG+ G +N+ET VEI +S+RG+++YI+Q+G ++N+N+MELLIM
Sbjct: 14 DLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIM 73
Query: 439 AYACKTSSASSIVGVIPYLPYSKHAK 516
ACK +SAS + VIP PY++ K
Sbjct: 74 INACKIASASRVTAVIPCFPYARQDK 99
Score = 86.2 bits (204), Expect = 1e-16
Identities = 40/78 (51%), Positives = 56/78 (71%)
Frame = +3
Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
K + R I +KL+A M+ +G HIITMDLH +IQGFFD PVDNL A P +L++I+E+I
Sbjct: 100 KDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENI 159
Query: 693 PDYRNSVIVARNPGSAKK 746
++RN IV+ + G AK+
Sbjct: 160 SEWRNCTIVSPDAGGAKR 177
>AL772400-2|CAI41098.1| 318|Homo sapiens phosphoribosyl
pyrophosphate synthetase 1 protein.
Length = 318
Score = 88.6 bits (210), Expect = 2e-17
Identities = 40/86 (46%), Positives = 61/86 (70%)
Frame = +1
Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
+L+ IA+RLG+ G +N+ET VEI +S+RG+++YI+Q+G ++N+N+MELLIM
Sbjct: 14 DLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIM 73
Query: 439 AYACKTSSASSIVGVIPYLPYSKHAK 516
ACK +SAS + VIP PY++ K
Sbjct: 74 INACKIASASRVTAVIPCFPYARQDK 99
Score = 86.2 bits (204), Expect = 1e-16
Identities = 40/78 (51%), Positives = 56/78 (71%)
Frame = +3
Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
K + R I +KL+A M+ +G HIITMDLH +IQGFFD PVDNL A P +L++I+E+I
Sbjct: 100 KDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENI 159
Query: 693 PDYRNSVIVARNPGSAKK 746
++RN IV+ + G AK+
Sbjct: 160 SEWRNCTIVSPDAGGAKR 177
>AL772400-1|CAI41097.1| 168|Homo sapiens phosphoribosyl
pyrophosphate synthetase 1 protein.
Length = 168
Score = 88.6 bits (210), Expect = 2e-17
Identities = 40/86 (46%), Positives = 61/86 (70%)
Frame = +1
Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
+L+ IA+RLG+ G +N+ET VEI +S+RG+++YI+Q+G ++N+N+MELLIM
Sbjct: 14 DLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIM 73
Query: 439 AYACKTSSASSIVGVIPYLPYSKHAK 516
ACK +SAS + VIP PY++ K
Sbjct: 74 INACKIASASRVTAVIPCFPYARQDK 99
Score = 39.1 bits (87), Expect = 0.017
Identities = 18/36 (50%), Positives = 24/36 (66%)
Frame = +3
Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQ 620
K + R I +KL+A M+ +G HIITMDLH +IQ
Sbjct: 100 KDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQ 135
>AL137787-2|CAI42173.1| 318|Homo sapiens phosphoribosyl
pyrophosphate synthetase 1 protein.
Length = 318
Score = 88.6 bits (210), Expect = 2e-17
Identities = 40/86 (46%), Positives = 61/86 (70%)
Frame = +1
Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
+L+ IA+RLG+ G +N+ET VEI +S+RG+++YI+Q+G ++N+N+MELLIM
Sbjct: 14 DLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIM 73
Query: 439 AYACKTSSASSIVGVIPYLPYSKHAK 516
ACK +SAS + VIP PY++ K
Sbjct: 74 INACKIASASRVTAVIPCFPYARQDK 99
Score = 86.2 bits (204), Expect = 1e-16
Identities = 40/78 (51%), Positives = 56/78 (71%)
Frame = +3
Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
K + R I +KL+A M+ +G HIITMDLH +IQGFFD PVDNL A P +L++I+E+I
Sbjct: 100 KDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENI 159
Query: 693 PDYRNSVIVARNPGSAKK 746
++RN IV+ + G AK+
Sbjct: 160 SEWRNCTIVSPDAGGAKR 177
>AL137787-1|CAI42172.1| 168|Homo sapiens phosphoribosyl
pyrophosphate synthetase 1 protein.
Length = 168
Score = 88.6 bits (210), Expect = 2e-17
Identities = 40/86 (46%), Positives = 61/86 (70%)
Frame = +1
Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
+L+ IA+RLG+ G +N+ET VEI +S+RG+++YI+Q+G ++N+N+MELLIM
Sbjct: 14 DLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIM 73
Query: 439 AYACKTSSASSIVGVIPYLPYSKHAK 516
ACK +SAS + VIP PY++ K
Sbjct: 74 INACKIASASRVTAVIPCFPYARQDK 99
Score = 39.1 bits (87), Expect = 0.017
Identities = 18/36 (50%), Positives = 24/36 (66%)
Frame = +3
Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQ 620
K + R I +KL+A M+ +G HIITMDLH +IQ
Sbjct: 100 KDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQ 135
>AK223169-1|BAD96889.1| 318|Homo sapiens phosphoribosyl
pyrophosphate synthetase 1 variant protein.
Length = 318
Score = 88.6 bits (210), Expect = 2e-17
Identities = 40/86 (46%), Positives = 61/86 (70%)
Frame = +1
Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
+L+ IA+RLG+ G +N+ET VEI +S+RG+++YI+Q+G ++N+N+MELLIM
Sbjct: 14 DLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIM 73
Query: 439 AYACKTSSASSIVGVIPYLPYSKHAK 516
ACK +SAS + VIP PY++ K
Sbjct: 74 INACKIASASRVTAVIPCFPYARQDK 99
Score = 87.4 bits (207), Expect = 5e-17
Identities = 40/78 (51%), Positives = 57/78 (73%)
Frame = +3
Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
K + R I +KL+A M+ ++G HIITMDLH +IQGFFD PVDNL A P +L++I+E+I
Sbjct: 100 KDKSRAPISAKLVANMLSEAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENI 159
Query: 693 PDYRNSVIVARNPGSAKK 746
++RN IV+ + G AK+
Sbjct: 160 SEWRNCTIVSPDAGGAKR 177
>Y00971-1|CAA68785.1| 318|Homo sapiens protein ( Human mRNA for
phosphoriobosyl pyrophosphate synthetase subunit II (EC
2.7.6.1). ).
Length = 318
Score = 87.8 bits (208), Expect = 4e-17
Identities = 40/78 (51%), Positives = 57/78 (73%)
Frame = +3
Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
K + R I +KL+A M+ +G HIITMDLH +IQGFFD PVDNL A P +LQ+I+E+I
Sbjct: 100 KDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENI 159
Query: 693 PDYRNSVIVARNPGSAKK 746
+++N +IV+ + G AK+
Sbjct: 160 AEWKNCIIVSPDAGGAKR 177
Score = 87.0 bits (206), Expect = 6e-17
Identities = 39/86 (45%), Positives = 61/86 (70%)
Frame = +1
Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
+L+ +A+RLG+ G +N+ET VEI +S+RG+++YIIQ+G ++N+N+MELLIM
Sbjct: 14 DLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGCGEINDNLMELLIM 73
Query: 439 AYACKTSSASSIVGVIPYLPYSKHAK 516
ACK +S+S + VIP PY++ K
Sbjct: 74 INACKIASSSRVTAVIPCFPYARQDK 99
>BC119663-1|AAI19664.1| 318|Homo sapiens phosphoribosyl
pyrophosphate synthetase 2 protein.
Length = 318
Score = 87.8 bits (208), Expect = 4e-17
Identities = 40/78 (51%), Positives = 57/78 (73%)
Frame = +3
Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
K + R I +KL+A M+ +G HIITMDLH +IQGFFD PVDNL A P +LQ+I+E+I
Sbjct: 100 KDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENI 159
Query: 693 PDYRNSVIVARNPGSAKK 746
+++N +IV+ + G AK+
Sbjct: 160 AEWKNCIIVSPDAGGAKR 177
Score = 87.0 bits (206), Expect = 6e-17
Identities = 39/86 (45%), Positives = 61/86 (70%)
Frame = +1
Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
+L+ +A+RLG+ G +N+ET VEI +S+RG+++YIIQ+G ++N+N+MELLIM
Sbjct: 14 DLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGCGEINDNLMELLIM 73
Query: 439 AYACKTSSASSIVGVIPYLPYSKHAK 516
ACK +S+S + VIP PY++ K
Sbjct: 74 INACKIASSSRVTAVIPCFPYARQDK 99
>BC110875-1|AAI10876.2| 318|Homo sapiens phosphoribosyl
pyrophosphate synthetase 2 protein.
Length = 318
Score = 87.8 bits (208), Expect = 4e-17
Identities = 40/78 (51%), Positives = 57/78 (73%)
Frame = +3
Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
K + R I +KL+A M+ +G HIITMDLH +IQGFFD PVDNL A P +LQ+I+E+I
Sbjct: 100 KDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENI 159
Query: 693 PDYRNSVIVARNPGSAKK 746
+++N +IV+ + G AK+
Sbjct: 160 AEWKNCIIVSPDAGGAKR 177
Score = 87.0 bits (206), Expect = 6e-17
Identities = 39/86 (45%), Positives = 61/86 (70%)
Frame = +1
Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
+L+ +A+RLG+ G +N+ET VEI +S+RG+++YIIQ+G ++N+N+MELLIM
Sbjct: 14 DLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGCGEINDNLMELLIM 73
Query: 439 AYACKTSSASSIVGVIPYLPYSKHAK 516
ACK +S+S + VIP PY++ K
Sbjct: 74 INACKIASSSRVTAVIPCFPYARQDK 99
>BC040483-1|AAH40483.3| 318|Homo sapiens phosphoribosyl
pyrophosphate synthetase 2 protein.
Length = 318
Score = 87.8 bits (208), Expect = 4e-17
Identities = 40/78 (51%), Positives = 57/78 (73%)
Frame = +3
Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
K + R I +KL+A M+ +G HIITMDLH +IQGFFD PVDNL A P +LQ+I+E+I
Sbjct: 100 KDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENI 159
Query: 693 PDYRNSVIVARNPGSAKK 746
+++N +IV+ + G AK+
Sbjct: 160 AEWKNCIIVSPDAGGAKR 177
Score = 87.0 bits (206), Expect = 6e-17
Identities = 39/86 (45%), Positives = 61/86 (70%)
Frame = +1
Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
+L+ +A+RLG+ G +N+ET VEI +S+RG+++YIIQ+G ++N+N+MELLIM
Sbjct: 14 DLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGCGEINDNLMELLIM 73
Query: 439 AYACKTSSASSIVGVIPYLPYSKHAK 516
ACK +S+S + VIP PY++ K
Sbjct: 74 INACKIASSSRVTAVIPCFPYARQDK 99
>BC030019-1|AAH30019.2| 346|Homo sapiens PRPS2 protein protein.
Length = 346
Score = 87.8 bits (208), Expect = 4e-17
Identities = 40/78 (51%), Positives = 57/78 (73%)
Frame = +3
Query: 513 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 692
K + R I +KL+A M+ +G HIITMDLH +IQGFFD PVDNL A P +LQ+I+E+I
Sbjct: 128 KDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENI 187
Query: 693 PDYRNSVIVARNPGSAKK 746
+++N +IV+ + G AK+
Sbjct: 188 AEWKNCIIVSPDAGGAKR 205
Score = 87.0 bits (206), Expect = 6e-17
Identities = 39/86 (45%), Positives = 61/86 (70%)
Frame = +1
Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
+L+ +A+RLG+ G +N+ET VEI +S+RG+++YIIQ+G ++N+N+MELLIM
Sbjct: 42 DLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGCGEINDNLMELLIM 101
Query: 439 AYACKTSSASSIVGVIPYLPYSKHAK 516
ACK +S+S + VIP PY++ K
Sbjct: 102 INACKIASSSRVTAVIPCFPYARQDK 127
>BC119662-1|AAI19663.1| 321|Homo sapiens phosphoribosyl
pyrophosphate synthetase 2 protein.
Length = 321
Score = 87.0 bits (206), Expect = 6e-17
Identities = 39/86 (45%), Positives = 61/86 (70%)
Frame = +1
Query: 259 ELADLIANRLGVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIM 438
+L+ +A+RLG+ G +N+ET VEI +S+RG+++YIIQ+G ++N+N+MELLIM
Sbjct: 14 DLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGCGEINDNLMELLIM 73
Query: 439 AYACKTSSASSIVGVIPYLPYSKHAK 516
ACK +S+S + VIP PY++ K
Sbjct: 74 INACKIASSSRVTAVIPCFPYARQDK 99
Score = 86.2 bits (204), Expect = 1e-16
Identities = 39/74 (52%), Positives = 55/74 (74%)
Frame = +3
Query: 525 RGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIPDYR 704
R I +KL+A M+ +G HIITMDLH +IQGFFD PVDNL A P +LQ+I+E+I +++
Sbjct: 107 RAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENIAEWK 166
Query: 705 NSVIVARNPGSAKK 746
N +IV+ + G AK+
Sbjct: 167 NCIIVSPDAGGAKR 180
>AL772400-3|CAI41099.1| 218|Homo sapiens phosphoribosyl
pyrophosphate synthetase 1 protein.
Length = 218
Score = 52.8 bits (121), Expect = 1e-06
Identities = 23/46 (50%), Positives = 35/46 (76%)
Frame = +3
Query: 609 KEIQGFFDCPVDNLRASPFLLQYIQESIPDYRNSVIVARNPGSAKK 746
K+ +GFFD PVDNL A P +L++I+E+I ++RN IV+ + G AK+
Sbjct: 32 KKDKGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKR 77
Score = 39.9 bits (89), Expect = 0.010
Identities = 18/32 (56%), Positives = 22/32 (68%)
Frame = +1
Query: 421 MELLIMAYACKTSSASSIVGVIPYLPYSKHAK 516
MELLIM ACK +SAS + VIP PY++ K
Sbjct: 1 MELLIMINACKIASASRVTAVIPCFPYARQDK 32
>AL137787-3|CAI42174.1| 218|Homo sapiens phosphoribosyl
pyrophosphate synthetase 1 protein.
Length = 218
Score = 52.8 bits (121), Expect = 1e-06
Identities = 23/46 (50%), Positives = 35/46 (76%)
Frame = +3
Query: 609 KEIQGFFDCPVDNLRASPFLLQYIQESIPDYRNSVIVARNPGSAKK 746
K+ +GFFD PVDNL A P +L++I+E+I ++RN IV+ + G AK+
Sbjct: 32 KKDKGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKR 77
Score = 39.9 bits (89), Expect = 0.010
Identities = 18/32 (56%), Positives = 22/32 (68%)
Frame = +1
Query: 421 MELLIMAYACKTSSASSIVGVIPYLPYSKHAK 516
MELLIM ACK +SAS + VIP PY++ K
Sbjct: 1 MELLIMINACKIASASRVTAVIPCFPYARQDK 32
>AK130921-1|BAC85460.1| 572|Homo sapiens protein ( Homo sapiens
cDNA FLJ27411 fis, clone WMC04903, highly similar to
Myosin light chain kinase, smooth muscle and non-muscle
isozymes ).
Length = 572
Score = 33.5 bits (73), Expect = 0.84
Identities = 18/61 (29%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Frame = -1
Query: 345 HNGLSVSLVVY*TTS---FTHT*AVGNQIS*FRSEFPLKITMSDVEFPSILQF*DLFDKP 175
H G SV+ ++Y TTS F + ++G +++ F+ F + ++FP+ QF +L +
Sbjct: 139 HEGTSVTNLLYPTTSYLEFETSVSIGTEVTPFQEHFGIYTGKISIDFPTAAQFDNLVEAE 198
Query: 174 T 172
T
Sbjct: 199 T 199
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 113,809,150
Number of Sequences: 237096
Number of extensions: 2546140
Number of successful extensions: 3230
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 3090
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3230
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9144232952
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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