Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= e40h0370
(711 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF495911-1|AAN60443.1| 6884|Homo sapiens nesprin-2 protein. 33 1.3
AF435011-1|AAL33548.1| 6885|Homo sapiens NUANCE protein. 33 1.3
BC110833-1|AAI10834.1| 952|Homo sapiens POLR1B protein protein. 30 7.1
BC096748-1|AAH96748.1| 594|Homo sapiens POLR1B protein protein. 30 7.1
BC073857-1|AAH73857.1| 560|Homo sapiens POLR1B protein protein. 30 7.1
BC004882-1|AAH04882.4| 582|Homo sapiens POLR1B protein protein. 30 7.1
AK128044-1|BAC87247.1| 1135|Homo sapiens protein ( Homo sapiens ... 30 7.1
AK022890-1|BAB14296.1| 714|Homo sapiens protein ( Homo sapiens ... 30 7.1
AK022533-1|BAB14082.1| 1079|Homo sapiens protein ( Homo sapiens ... 30 7.1
AC012442-2|AAX81999.1| 1135|Homo sapiens unknown protein. 30 7.1
U87946-1|AAD00648.1| 557|Homo sapiens paxillin protein. 30 9.4
U14588-1|AAC50104.1| 557|Homo sapiens paxillin protein. 30 9.4
D86863-1|BAA18998.1| 605|Homo sapiens paxillin gamma protein. 30 9.4
D86862-1|BAA18997.1| 591|Homo sapiens paxillin beta protein. 30 9.4
BC003647-1|AAH03647.2| 169|Homo sapiens PXN protein protein. 30 9.4
AK128712-1|BAC87586.1| 403|Homo sapiens protein ( Homo sapiens ... 30 9.4
AC004263-2|AAC05175.1| 605|Homo sapiens cytoskeletal protein pr... 30 9.4
>AF495911-1|AAN60443.1| 6884|Homo sapiens nesprin-2 protein.
Length = 6884
Score = 32.7 bits (71), Expect = 1.3
Identities = 25/83 (30%), Positives = 42/83 (50%)
Frame = +3
Query: 66 INSRAYKKDLEEKRSLMKSEDILRNIGDAIKKKAPFEAVMPSEKISPPTVGDLADCTDSN 245
+NS K LEE+ +K +L+ GDA + +A + T+ D+++ D N
Sbjct: 2066 LNSSEGKMPLEERIQKIKEIILLKPEGDARIETIMKQAESSEAPLVQKTLTDISNQWD-N 2124
Query: 246 TIHLMSFYMIRMNLKI*LKRKKY 314
T+HL S Y+ K+ L+ +KY
Sbjct: 2125 TLHLASTYLSHQE-KLLLEGEKY 2146
>AF435011-1|AAL33548.1| 6885|Homo sapiens NUANCE protein.
Length = 6885
Score = 32.7 bits (71), Expect = 1.3
Identities = 25/83 (30%), Positives = 42/83 (50%)
Frame = +3
Query: 66 INSRAYKKDLEEKRSLMKSEDILRNIGDAIKKKAPFEAVMPSEKISPPTVGDLADCTDSN 245
+NS K LEE+ +K +L+ GDA + +A + T+ D+++ D N
Sbjct: 2067 LNSSEGKMPLEERIQKIKEIILLKPEGDARIETIMKQAESSEAPLVQKTLTDISNQWD-N 2125
Query: 246 TIHLMSFYMIRMNLKI*LKRKKY 314
T+HL S Y+ K+ L+ +KY
Sbjct: 2126 TLHLASTYLSHQE-KLLLEGEKY 2147
>BC110833-1|AAI10834.1| 952|Homo sapiens POLR1B protein protein.
Length = 952
Score = 30.3 bits (65), Expect = 7.1
Identities = 16/53 (30%), Positives = 30/53 (56%), Gaps = 1/53 (1%)
Frame = -1
Query: 663 KYDYISSSYNIFLV*NIRMNDFYA-ISVHRELINNFLLNITTFFVHFNSHNSS 508
K + I + IF+ I ++ +A ++ H+EL + LL++ F+ F+ HN S
Sbjct: 447 KEELIGTMEQIFMNVAIFEDEVFAGVTTHQELFPHSLLSVIANFIPFSDHNQS 499
>BC096748-1|AAH96748.1| 594|Homo sapiens POLR1B protein protein.
Length = 594
Score = 30.3 bits (65), Expect = 7.1
Identities = 16/53 (30%), Positives = 30/53 (56%), Gaps = 1/53 (1%)
Frame = -1
Query: 663 KYDYISSSYNIFLV*NIRMNDFYA-ISVHRELINNFLLNITTFFVHFNSHNSS 508
K + I + IF+ I ++ +A ++ H+EL + LL++ F+ F+ HN S
Sbjct: 89 KEELIGTMEQIFMNVAIFEDEVFAGVTTHQELFPHSLLSVIANFIPFSDHNQS 141
>BC073857-1|AAH73857.1| 560|Homo sapiens POLR1B protein protein.
Length = 560
Score = 30.3 bits (65), Expect = 7.1
Identities = 16/53 (30%), Positives = 30/53 (56%), Gaps = 1/53 (1%)
Frame = -1
Query: 663 KYDYISSSYNIFLV*NIRMNDFYA-ISVHRELINNFLLNITTFFVHFNSHNSS 508
K + I + IF+ I ++ +A ++ H+EL + LL++ F+ F+ HN S
Sbjct: 55 KEELIGTMEQIFMNVAIFEDEVFAGVTTHQELFPHSLLSVIANFIPFSDHNQS 107
>BC004882-1|AAH04882.4| 582|Homo sapiens POLR1B protein protein.
Length = 582
Score = 30.3 bits (65), Expect = 7.1
Identities = 16/53 (30%), Positives = 30/53 (56%), Gaps = 1/53 (1%)
Frame = -1
Query: 663 KYDYISSSYNIFLV*NIRMNDFYA-ISVHRELINNFLLNITTFFVHFNSHNSS 508
K + I + IF+ I ++ +A ++ H+EL + LL++ F+ F+ HN S
Sbjct: 77 KEELIGTMEQIFMNVAIFEDEVFAGVTTHQELFPHSLLSVIANFIPFSDHNQS 129
>AK128044-1|BAC87247.1| 1135|Homo sapiens protein ( Homo sapiens
cDNA FLJ46164 fis, clone TESTI4002799, highly similar
to DNA-directed RNA polymerase I 135 kDa polypeptide (EC
2.7.7.6). ).
Length = 1135
Score = 30.3 bits (65), Expect = 7.1
Identities = 16/53 (30%), Positives = 30/53 (56%), Gaps = 1/53 (1%)
Frame = -1
Query: 663 KYDYISSSYNIFLV*NIRMNDFYA-ISVHRELINNFLLNITTFFVHFNSHNSS 508
K + I + IF+ I ++ +A ++ H+EL + LL++ F+ F+ HN S
Sbjct: 630 KEELIGTMEQIFMNVAIFEDEVFAGVTTHQELFPHSLLSVIANFIPFSDHNQS 682
>AK022890-1|BAB14296.1| 714|Homo sapiens protein ( Homo sapiens
cDNA FLJ12828 fis, clone NT2RP2002993, highly similar to
DNA-DIRECTED RNA POLYMERASE I 135 KD POLYPEPTIDE (EC
2.7.7.6). ).
Length = 714
Score = 30.3 bits (65), Expect = 7.1
Identities = 16/53 (30%), Positives = 30/53 (56%), Gaps = 1/53 (1%)
Frame = -1
Query: 663 KYDYISSSYNIFLV*NIRMNDFYA-ISVHRELINNFLLNITTFFVHFNSHNSS 508
K + I + IF+ I ++ +A ++ H+EL + LL++ F+ F+ HN S
Sbjct: 209 KEELIGTMEQIFMNVAIFEDEVFAGVTTHQELFPHSLLSVIANFIPFSDHNQS 261
>AK022533-1|BAB14082.1| 1079|Homo sapiens protein ( Homo sapiens
cDNA FLJ12471 fis, clone NT2RM1000894, highly similar to
DNA-DIRECTED RNA POLYMERASE I 135 KD POLYPEPTIDE (EC
2.7.7.6). ).
Length = 1079
Score = 30.3 bits (65), Expect = 7.1
Identities = 16/53 (30%), Positives = 30/53 (56%), Gaps = 1/53 (1%)
Frame = -1
Query: 663 KYDYISSSYNIFLV*NIRMNDFYA-ISVHRELINNFLLNITTFFVHFNSHNSS 508
K + I + IF+ I ++ +A ++ H+EL + LL++ F+ F+ HN S
Sbjct: 574 KEELIGTMEQIFMNVAIFEDEVFAGVTTHQELFPHSLLSVIANFIPFSDHNQS 626
>AC012442-2|AAX81999.1| 1135|Homo sapiens unknown protein.
Length = 1135
Score = 30.3 bits (65), Expect = 7.1
Identities = 16/53 (30%), Positives = 30/53 (56%), Gaps = 1/53 (1%)
Frame = -1
Query: 663 KYDYISSSYNIFLV*NIRMNDFYA-ISVHRELINNFLLNITTFFVHFNSHNSS 508
K + I + IF+ I ++ +A ++ H+EL + LL++ F+ F+ HN S
Sbjct: 630 KEELIGTMEQIFMNVAIFEDEVFAGVTTHQELFPHSLLSVIANFIPFSDHNQS 682
>U87946-1|AAD00648.1| 557|Homo sapiens paxillin protein.
Length = 557
Score = 29.9 bits (64), Expect = 9.4
Identities = 15/54 (27%), Positives = 28/54 (51%)
Frame = -1
Query: 165 LFSLWHPQCFLKYLLISSKIFSPLNLFYMLDY*STVLYLLIHHHQVQGTFPAGC 4
L +LWHP+CF + + F+P ++ Y +H+H+ +G+ +GC
Sbjct: 457 LNTLWHPECF-----VCRECFTPFVNGSFFEH-DGQPYCEVHYHERRGSLCSGC 504
>U14588-1|AAC50104.1| 557|Homo sapiens paxillin protein.
Length = 557
Score = 29.9 bits (64), Expect = 9.4
Identities = 15/54 (27%), Positives = 28/54 (51%)
Frame = -1
Query: 165 LFSLWHPQCFLKYLLISSKIFSPLNLFYMLDY*STVLYLLIHHHQVQGTFPAGC 4
L +LWHP+CF + + F+P ++ Y +H+H+ +G+ +GC
Sbjct: 457 LNTLWHPECF-----VCRECFTPFVNGSFFEH-DGQPYCEVHYHERRGSLCSGC 504
>D86863-1|BAA18998.1| 605|Homo sapiens paxillin gamma protein.
Length = 605
Score = 29.9 bits (64), Expect = 9.4
Identities = 15/54 (27%), Positives = 28/54 (51%)
Frame = -1
Query: 165 LFSLWHPQCFLKYLLISSKIFSPLNLFYMLDY*STVLYLLIHHHQVQGTFPAGC 4
L +LWHP+CF + + F+P ++ Y +H+H+ +G+ +GC
Sbjct: 505 LNTLWHPECF-----VCRECFTPFVNGSFFEH-DGQPYCEVHYHERRGSLCSGC 552
>D86862-1|BAA18997.1| 591|Homo sapiens paxillin beta protein.
Length = 591
Score = 29.9 bits (64), Expect = 9.4
Identities = 15/54 (27%), Positives = 28/54 (51%)
Frame = -1
Query: 165 LFSLWHPQCFLKYLLISSKIFSPLNLFYMLDY*STVLYLLIHHHQVQGTFPAGC 4
L +LWHP+CF + + F+P ++ Y +H+H+ +G+ +GC
Sbjct: 491 LNTLWHPECF-----VCRECFTPFVNGSFFEH-DGQPYCEVHYHERRGSLCSGC 538
>BC003647-1|AAH03647.2| 169|Homo sapiens PXN protein protein.
Length = 169
Score = 29.9 bits (64), Expect = 9.4
Identities = 15/54 (27%), Positives = 28/54 (51%)
Frame = -1
Query: 165 LFSLWHPQCFLKYLLISSKIFSPLNLFYMLDY*STVLYLLIHHHQVQGTFPAGC 4
L +LWHP+CF + + F+P ++ Y +H+H+ +G+ +GC
Sbjct: 55 LNTLWHPECF-----VCRECFTPFVNGSFFEH-DGQPYCEVHYHERRGSLCSGC 102
>AK128712-1|BAC87586.1| 403|Homo sapiens protein ( Homo sapiens
cDNA FLJ46879 fis, clone UTERU3015011, highly similar
to Paxillin. ).
Length = 403
Score = 29.9 bits (64), Expect = 9.4
Identities = 15/54 (27%), Positives = 28/54 (51%)
Frame = -1
Query: 165 LFSLWHPQCFLKYLLISSKIFSPLNLFYMLDY*STVLYLLIHHHQVQGTFPAGC 4
L +LWHP+CF + + F+P ++ Y +H+H+ +G+ +GC
Sbjct: 303 LNTLWHPECF-----VCRECFTPFVNGSFFEH-DGQPYCEVHYHERRGSLCSGC 350
>AC004263-2|AAC05175.1| 605|Homo sapiens cytoskeletal protein
protein.
Length = 605
Score = 29.9 bits (64), Expect = 9.4
Identities = 15/54 (27%), Positives = 28/54 (51%)
Frame = -1
Query: 165 LFSLWHPQCFLKYLLISSKIFSPLNLFYMLDY*STVLYLLIHHHQVQGTFPAGC 4
L +LWHP+CF + + F+P ++ Y +H+H+ +G+ +GC
Sbjct: 505 LNTLWHPECF-----VCRECFTPFVNGSFFEH-DGQPYCEVHYHERRGSLCSGC 552
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 91,177,643
Number of Sequences: 237096
Number of extensions: 1787747
Number of successful extensions: 4243
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 4118
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4236
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8287202872
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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