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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= e40h0357
         (696 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

X67698-1|CAA47928.1|  151|Homo sapiens protein ( H.sapiens tissu...    72   2e-12
BC002532-1|AAH02532.1|  151|Homo sapiens Niemann-Pick disease, t...    72   2e-12
AK222474-1|BAD96194.1|  151|Homo sapiens Niemann-Pick disease, t...    72   2e-12
BC038953-1|AAH38953.1|  444|Homo sapiens COG3 protein protein.         31   5.2  
AL606514-2|CAH73267.1|  828|Homo sapiens component of oligomeric...    31   5.2  
AL139326-1|CAH72888.1|  828|Homo sapiens component of oligomeric...    31   5.2  
AF349676-1|AAK66974.1|  828|Homo sapiens vesicle docking protein...    31   5.2  
AF332595-1|AAK06848.1|  828|Homo sapiens tethering factor SEC34 ...    31   5.2  

>X67698-1|CAA47928.1|  151|Homo sapiens protein ( H.sapiens tissue
           specific mRNA. ).
          Length = 151

 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 29/76 (38%), Positives = 48/76 (63%), Gaps = 1/76 (1%)
 Frame = +3

Query: 282 VHGVIMNIPIPFPLPESDACKDNGLTCPLKEGTLADYKATLPILKSYPKVTVEVKWELQS 461
           VHG++M +P+PFP+PE D CK +G+ CP+++     Y   LP+   YP + + V+W+LQ 
Sbjct: 74  VHGILMGVPVPFPIPEPDGCK-SGINCPIQKDKTYSYLNKLPVKSEYPSIKLVVEWQLQD 132

Query: 462 E-HGDLVCVLINAKLV 506
           + +  L C  I  ++V
Sbjct: 133 DKNQSLFCWEIPVQIV 148



 Score = 33.5 bits (73), Expect = 0.74
 Identities = 19/57 (33%), Positives = 26/57 (45%)
 Frame = +1

Query: 79  FFITAAVLLASAEAKFFKDCGSKLATVHNVTVSGCEESSSHCILKRNTDATIGLQFT 249
           F + A    A AE   FKDCGS    +  V VS C   +  C L +    ++ + FT
Sbjct: 8   FLLLALSTAAQAEPVQFKDCGSVDGVIKEVNVSPC--PTQPCQLSKGQSYSVNVTFT 62


>BC002532-1|AAH02532.1|  151|Homo sapiens Niemann-Pick disease, type
           C2 protein.
          Length = 151

 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 29/76 (38%), Positives = 48/76 (63%), Gaps = 1/76 (1%)
 Frame = +3

Query: 282 VHGVIMNIPIPFPLPESDACKDNGLTCPLKEGTLADYKATLPILKSYPKVTVEVKWELQS 461
           VHG++M +P+PFP+PE D CK +G+ CP+++     Y   LP+   YP + + V+W+LQ 
Sbjct: 74  VHGILMGVPVPFPIPEPDGCK-SGINCPIQKDKTYSYLNKLPVKSEYPSIKLVVEWQLQD 132

Query: 462 E-HGDLVCVLINAKLV 506
           + +  L C  I  ++V
Sbjct: 133 DKNQSLFCWEIPVQIV 148



 Score = 33.5 bits (73), Expect = 0.74
 Identities = 19/57 (33%), Positives = 26/57 (45%)
 Frame = +1

Query: 79  FFITAAVLLASAEAKFFKDCGSKLATVHNVTVSGCEESSSHCILKRNTDATIGLQFT 249
           F + A    A AE   FKDCGS    +  V VS C   +  C L +    ++ + FT
Sbjct: 8   FLLLALSTAAQAEPVQFKDCGSVDGVIKEVNVSPC--PTQPCQLSKGQSYSVNVTFT 62


>AK222474-1|BAD96194.1|  151|Homo sapiens Niemann-Pick disease, type
           C2 precursor variant protein.
          Length = 151

 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 29/76 (38%), Positives = 48/76 (63%), Gaps = 1/76 (1%)
 Frame = +3

Query: 282 VHGVIMNIPIPFPLPESDACKDNGLTCPLKEGTLADYKATLPILKSYPKVTVEVKWELQS 461
           VHG++M +P+PFP+PE D CK +G+ CP+++     Y   LP+   YP + + V+W+LQ 
Sbjct: 74  VHGILMGVPVPFPIPEPDGCK-SGINCPIQKDKTYSYLNKLPVKSEYPSIKLVVEWQLQD 132

Query: 462 E-HGDLVCVLINAKLV 506
           + +  L C  I  ++V
Sbjct: 133 DKNQSLFCWEIPVQIV 148



 Score = 32.3 bits (70), Expect = 1.7
 Identities = 18/57 (31%), Positives = 26/57 (45%)
 Frame = +1

Query: 79  FFITAAVLLASAEAKFFKDCGSKLATVHNVTVSGCEESSSHCILKRNTDATIGLQFT 249
           F + A    A AE   F+DCGS    +  V VS C   +  C L +    ++ + FT
Sbjct: 8   FLLLALSTAAQAEPVQFRDCGSVDGVIKEVNVSPC--PTQPCQLSKGQSYSVNVTFT 62


>BC038953-1|AAH38953.1|  444|Homo sapiens COG3 protein protein.
          Length = 444

 Score = 30.7 bits (66), Expect = 5.2
 Identities = 18/73 (24%), Positives = 31/73 (42%)
 Frame = +3

Query: 222 RRHDRPAVYTTHNIDRINTEVHGVIMNIPIPFPLPESDACKDNGLTCPLKEGTLADYKAT 401
           RR D  A  T    D +  E+     N+P+P  LP  D C     + P++  ++      
Sbjct: 27  RRPDTTAPLTDRQTDSV-LELKAAAENLPVPAELPIEDLCSLTSQSLPIELTSVVPESTE 85

Query: 402 LPILKSYPKVTVE 440
             +LK +  + +E
Sbjct: 86  DILLKGFTSLGME 98


>AL606514-2|CAH73267.1|  828|Homo sapiens component of oligomeric
           golgi complex 3 protein.
          Length = 828

 Score = 30.7 bits (66), Expect = 5.2
 Identities = 18/73 (24%), Positives = 31/73 (42%)
 Frame = +3

Query: 222 RRHDRPAVYTTHNIDRINTEVHGVIMNIPIPFPLPESDACKDNGLTCPLKEGTLADYKAT 401
           RR D  A  T    D +  E+     N+P+P  LP  D C     + P++  ++      
Sbjct: 27  RRPDTTAPLTDRQTDSV-LELKAAAENLPVPAELPIEDLCSLTSQSLPIELTSVVPESTE 85

Query: 402 LPILKSYPKVTVE 440
             +LK +  + +E
Sbjct: 86  DILLKGFTSLGME 98


>AL139326-1|CAH72888.1|  828|Homo sapiens component of oligomeric
           golgi complex 3 protein.
          Length = 828

 Score = 30.7 bits (66), Expect = 5.2
 Identities = 18/73 (24%), Positives = 31/73 (42%)
 Frame = +3

Query: 222 RRHDRPAVYTTHNIDRINTEVHGVIMNIPIPFPLPESDACKDNGLTCPLKEGTLADYKAT 401
           RR D  A  T    D +  E+     N+P+P  LP  D C     + P++  ++      
Sbjct: 27  RRPDTTAPLTDRQTDSV-LELKAAAENLPVPAELPIEDLCSLTSQSLPIELTSVVPESTE 85

Query: 402 LPILKSYPKVTVE 440
             +LK +  + +E
Sbjct: 86  DILLKGFTSLGME 98


>AF349676-1|AAK66974.1|  828|Homo sapiens vesicle docking protein
           SEC34 protein.
          Length = 828

 Score = 30.7 bits (66), Expect = 5.2
 Identities = 18/73 (24%), Positives = 31/73 (42%)
 Frame = +3

Query: 222 RRHDRPAVYTTHNIDRINTEVHGVIMNIPIPFPLPESDACKDNGLTCPLKEGTLADYKAT 401
           RR D  A  T    D +  E+     N+P+P  LP  D C     + P++  ++      
Sbjct: 27  RRPDTTAPLTDRQTDSV-LELKAAAENLPVPAELPIEDLCSLTSQSLPIELTSVVPESTE 85

Query: 402 LPILKSYPKVTVE 440
             +LK +  + +E
Sbjct: 86  DILLKGFTSLGME 98


>AF332595-1|AAK06848.1|  828|Homo sapiens tethering factor SEC34
           protein.
          Length = 828

 Score = 30.7 bits (66), Expect = 5.2
 Identities = 18/73 (24%), Positives = 31/73 (42%)
 Frame = +3

Query: 222 RRHDRPAVYTTHNIDRINTEVHGVIMNIPIPFPLPESDACKDNGLTCPLKEGTLADYKAT 401
           RR D  A  T    D +  E+     N+P+P  LP  D C     + P++  ++      
Sbjct: 27  RRPDTTAPLTDRQTDSV-LELKAAAENLPVPAELPIEDLCSLTSQSLPIELTSVVPESTE 85

Query: 402 LPILKSYPKVTVE 440
             +LK +  + +E
Sbjct: 86  DILLKGFTSLGME 98


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 99,668,187
Number of Sequences: 237096
Number of extensions: 2120419
Number of successful extensions: 5538
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 5106
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5514
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8007229802
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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