Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= e40h0316
(577 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X67698-1|CAA47928.1| 151|Homo sapiens protein ( H.sapiens tissu... 72 1e-12
BC002532-1|AAH02532.1| 151|Homo sapiens Niemann-Pick disease, t... 72 1e-12
AK222474-1|BAD96194.1| 151|Homo sapiens Niemann-Pick disease, t... 72 1e-12
BC038953-1|AAH38953.1| 444|Homo sapiens COG3 protein protein. 31 3.8
AL606514-2|CAH73267.1| 828|Homo sapiens component of oligomeric... 31 3.8
AL139326-1|CAH72888.1| 828|Homo sapiens component of oligomeric... 31 3.8
AF349676-1|AAK66974.1| 828|Homo sapiens vesicle docking protein... 31 3.8
AF332595-1|AAK06848.1| 828|Homo sapiens tethering factor SEC34 ... 31 3.8
X82494-1|CAA57876.1| 1184|Homo sapiens fibulin-2 protein. 29 8.9
U48437-1|AAB96331.1| 650|Homo sapiens amyloid precursor-like pr... 29 8.9
BC051690-1|AAH51690.1| 1184|Homo sapiens fibulin 2 protein. 29 8.9
BC012889-1|AAH12889.1| 650|Homo sapiens amyloid beta (A4) precu... 29 8.9
AY130459-1|AAN05436.1| 1231|Homo sapiens fibulin 2 protein. 29 8.9
AY130458-1|AAN05435.1| 1231|Homo sapiens fibulin 2 protein. 29 8.9
AD000864-1|AAB50173.1| 650|Homo sapiens amyloid precursor-like ... 29 8.9
>X67698-1|CAA47928.1| 151|Homo sapiens protein ( H.sapiens tissue
specific mRNA. ).
Length = 151
Score = 72.1 bits (169), Expect = 1e-12
Identities = 26/67 (38%), Positives = 43/67 (64%)
Frame = +1
Query: 283 VHGVIMNIPIPFPLPESDACKDNGLTCPLKEGTLADYKATLPILKSYPKVTVEVKWELQS 462
VHG++M +P+PFP+PE D CK +G+ CP+++ Y LP+ YP + + V+W+LQ
Sbjct: 74 VHGILMGVPVPFPIPEPDGCK-SGINCPIQKDKTYSYLNKLPVKSEYPSIKLVVEWQLQD 132
Query: 463 EHGDLVF 483
+ +F
Sbjct: 133 DKNQSLF 139
Score = 33.9 bits (74), Expect = 0.41
Identities = 20/62 (32%), Positives = 27/62 (43%)
Frame = +2
Query: 80 FFITAAVLLASAEAKFFKDCGSKLATVHNVTVSGCEESSSHCILKRNTDATIGLQFTPRT 259
F + A A AE FKDCGS + V VS C + C L + ++ + FT
Sbjct: 8 FLLLALSTAAQAEPVQFKDCGSVDGVIKEVNVSPC--PTQPCQLSKGQSYSVNVTFTSNI 65
Query: 260 TS 265
S
Sbjct: 66 QS 67
>BC002532-1|AAH02532.1| 151|Homo sapiens Niemann-Pick disease, type
C2 protein.
Length = 151
Score = 72.1 bits (169), Expect = 1e-12
Identities = 26/67 (38%), Positives = 43/67 (64%)
Frame = +1
Query: 283 VHGVIMNIPIPFPLPESDACKDNGLTCPLKEGTLADYKATLPILKSYPKVTVEVKWELQS 462
VHG++M +P+PFP+PE D CK +G+ CP+++ Y LP+ YP + + V+W+LQ
Sbjct: 74 VHGILMGVPVPFPIPEPDGCK-SGINCPIQKDKTYSYLNKLPVKSEYPSIKLVVEWQLQD 132
Query: 463 EHGDLVF 483
+ +F
Sbjct: 133 DKNQSLF 139
Score = 33.9 bits (74), Expect = 0.41
Identities = 20/62 (32%), Positives = 27/62 (43%)
Frame = +2
Query: 80 FFITAAVLLASAEAKFFKDCGSKLATVHNVTVSGCEESSSHCILKRNTDATIGLQFTPRT 259
F + A A AE FKDCGS + V VS C + C L + ++ + FT
Sbjct: 8 FLLLALSTAAQAEPVQFKDCGSVDGVIKEVNVSPC--PTQPCQLSKGQSYSVNVTFTSNI 65
Query: 260 TS 265
S
Sbjct: 66 QS 67
>AK222474-1|BAD96194.1| 151|Homo sapiens Niemann-Pick disease, type
C2 precursor variant protein.
Length = 151
Score = 72.1 bits (169), Expect = 1e-12
Identities = 26/67 (38%), Positives = 43/67 (64%)
Frame = +1
Query: 283 VHGVIMNIPIPFPLPESDACKDNGLTCPLKEGTLADYKATLPILKSYPKVTVEVKWELQS 462
VHG++M +P+PFP+PE D CK +G+ CP+++ Y LP+ YP + + V+W+LQ
Sbjct: 74 VHGILMGVPVPFPIPEPDGCK-SGINCPIQKDKTYSYLNKLPVKSEYPSIKLVVEWQLQD 132
Query: 463 EHGDLVF 483
+ +F
Sbjct: 133 DKNQSLF 139
Score = 33.1 bits (72), Expect = 0.72
Identities = 19/62 (30%), Positives = 27/62 (43%)
Frame = +2
Query: 80 FFITAAVLLASAEAKFFKDCGSKLATVHNVTVSGCEESSSHCILKRNTDATIGLQFTPRT 259
F + A A AE F+DCGS + V VS C + C L + ++ + FT
Sbjct: 8 FLLLALSTAAQAEPVQFRDCGSVDGVIKEVNVSPC--PTQPCQLSKGQSYSVNVTFTSNV 65
Query: 260 TS 265
S
Sbjct: 66 QS 67
>BC038953-1|AAH38953.1| 444|Homo sapiens COG3 protein protein.
Length = 444
Score = 30.7 bits (66), Expect = 3.8
Identities = 18/73 (24%), Positives = 31/73 (42%)
Frame = +1
Query: 223 RRHDRPAVYTTHNIDRINTEVHGVIMNIPIPFPLPESDACKDNGLTCPLKEGTLADYKAT 402
RR D A T D + E+ N+P+P LP D C + P++ ++
Sbjct: 27 RRPDTTAPLTDRQTDSV-LELKAAAENLPVPAELPIEDLCSLTSQSLPIELTSVVPESTE 85
Query: 403 LPILKSYPKVTVE 441
+LK + + +E
Sbjct: 86 DILLKGFTSLGME 98
>AL606514-2|CAH73267.1| 828|Homo sapiens component of oligomeric
golgi complex 3 protein.
Length = 828
Score = 30.7 bits (66), Expect = 3.8
Identities = 18/73 (24%), Positives = 31/73 (42%)
Frame = +1
Query: 223 RRHDRPAVYTTHNIDRINTEVHGVIMNIPIPFPLPESDACKDNGLTCPLKEGTLADYKAT 402
RR D A T D + E+ N+P+P LP D C + P++ ++
Sbjct: 27 RRPDTTAPLTDRQTDSV-LELKAAAENLPVPAELPIEDLCSLTSQSLPIELTSVVPESTE 85
Query: 403 LPILKSYPKVTVE 441
+LK + + +E
Sbjct: 86 DILLKGFTSLGME 98
>AL139326-1|CAH72888.1| 828|Homo sapiens component of oligomeric
golgi complex 3 protein.
Length = 828
Score = 30.7 bits (66), Expect = 3.8
Identities = 18/73 (24%), Positives = 31/73 (42%)
Frame = +1
Query: 223 RRHDRPAVYTTHNIDRINTEVHGVIMNIPIPFPLPESDACKDNGLTCPLKEGTLADYKAT 402
RR D A T D + E+ N+P+P LP D C + P++ ++
Sbjct: 27 RRPDTTAPLTDRQTDSV-LELKAAAENLPVPAELPIEDLCSLTSQSLPIELTSVVPESTE 85
Query: 403 LPILKSYPKVTVE 441
+LK + + +E
Sbjct: 86 DILLKGFTSLGME 98
>AF349676-1|AAK66974.1| 828|Homo sapiens vesicle docking protein
SEC34 protein.
Length = 828
Score = 30.7 bits (66), Expect = 3.8
Identities = 18/73 (24%), Positives = 31/73 (42%)
Frame = +1
Query: 223 RRHDRPAVYTTHNIDRINTEVHGVIMNIPIPFPLPESDACKDNGLTCPLKEGTLADYKAT 402
RR D A T D + E+ N+P+P LP D C + P++ ++
Sbjct: 27 RRPDTTAPLTDRQTDSV-LELKAAAENLPVPAELPIEDLCSLTSQSLPIELTSVVPESTE 85
Query: 403 LPILKSYPKVTVE 441
+LK + + +E
Sbjct: 86 DILLKGFTSLGME 98
>AF332595-1|AAK06848.1| 828|Homo sapiens tethering factor SEC34
protein.
Length = 828
Score = 30.7 bits (66), Expect = 3.8
Identities = 18/73 (24%), Positives = 31/73 (42%)
Frame = +1
Query: 223 RRHDRPAVYTTHNIDRINTEVHGVIMNIPIPFPLPESDACKDNGLTCPLKEGTLADYKAT 402
RR D A T D + E+ N+P+P LP D C + P++ ++
Sbjct: 27 RRPDTTAPLTDRQTDSV-LELKAAAENLPVPAELPIEDLCSLTSQSLPIELTSVVPESTE 85
Query: 403 LPILKSYPKVTVE 441
+LK + + +E
Sbjct: 86 DILLKGFTSLGME 98
>X82494-1|CAA57876.1| 1184|Homo sapiens fibulin-2 protein.
Length = 1184
Score = 29.5 bits (63), Expect = 8.9
Identities = 10/15 (66%), Positives = 12/15 (80%)
Frame = +1
Query: 310 IPFPLPESDACKDNG 354
IP PLP+ + CKDNG
Sbjct: 673 IPLPLPQPNTCKDNG 687
>U48437-1|AAB96331.1| 650|Homo sapiens amyloid precursor-like
protein 1 protein.
Length = 650
Score = 29.5 bits (63), Expect = 8.9
Identities = 18/51 (35%), Positives = 22/51 (43%)
Frame = -1
Query: 457 GAPTLLPLSP*DKTSG*AVLLYNPPGFPP*GGRSARCPCTRQTPAGGTVSG 305
G+ LLP D+ G + PPG P G + P TR P G V G
Sbjct: 190 GSGMLLPCGS-DRFRGVEYVCCPPPGTPDPSGTAVGDPSTRSWPPGSRVEG 239
>BC051690-1|AAH51690.1| 1184|Homo sapiens fibulin 2 protein.
Length = 1184
Score = 29.5 bits (63), Expect = 8.9
Identities = 10/15 (66%), Positives = 12/15 (80%)
Frame = +1
Query: 310 IPFPLPESDACKDNG 354
IP PLP+ + CKDNG
Sbjct: 673 IPLPLPQPNTCKDNG 687
>BC012889-1|AAH12889.1| 650|Homo sapiens amyloid beta (A4)
precursor-like protein 1 protein.
Length = 650
Score = 29.5 bits (63), Expect = 8.9
Identities = 18/51 (35%), Positives = 22/51 (43%)
Frame = -1
Query: 457 GAPTLLPLSP*DKTSG*AVLLYNPPGFPP*GGRSARCPCTRQTPAGGTVSG 305
G+ LLP D+ G + PPG P G + P TR P G V G
Sbjct: 190 GSGMLLPCGS-DRFRGVEYVCCPPPGTPDPSGTAVGDPSTRSWPPGSRVEG 239
>AY130459-1|AAN05436.1| 1231|Homo sapiens fibulin 2 protein.
Length = 1231
Score = 29.5 bits (63), Expect = 8.9
Identities = 10/15 (66%), Positives = 12/15 (80%)
Frame = +1
Query: 310 IPFPLPESDACKDNG 354
IP PLP+ + CKDNG
Sbjct: 673 IPLPLPQPNTCKDNG 687
>AY130458-1|AAN05435.1| 1231|Homo sapiens fibulin 2 protein.
Length = 1231
Score = 29.5 bits (63), Expect = 8.9
Identities = 10/15 (66%), Positives = 12/15 (80%)
Frame = +1
Query: 310 IPFPLPESDACKDNG 354
IP PLP+ + CKDNG
Sbjct: 673 IPLPLPQPNTCKDNG 687
>AD000864-1|AAB50173.1| 650|Homo sapiens amyloid precursor-like
protein 1 protein.
Length = 650
Score = 29.5 bits (63), Expect = 8.9
Identities = 18/51 (35%), Positives = 22/51 (43%)
Frame = -1
Query: 457 GAPTLLPLSP*DKTSG*AVLLYNPPGFPP*GGRSARCPCTRQTPAGGTVSG 305
G+ LLP D+ G + PPG P G + P TR P G V G
Sbjct: 190 GSGMLLPCGS-DRFRGVEYVCCPPPGTPDPSGTAVGDPSTRSWPPGSRVEG 239
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 83,462,814
Number of Sequences: 237096
Number of extensions: 1845626
Number of successful extensions: 4866
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 4499
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4844
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 5929224630
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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