Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= e40h0293
(637 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000DB72A4 Cluster: PREDICTED: similar to 3-phosphog... 127 2e-28
UniRef50_UPI00015B605A Cluster: PREDICTED: similar to GA19489-PA... 126 4e-28
UniRef50_O43175 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 120 4e-26
UniRef50_A7SFV8 Cluster: Predicted protein; n=1; Nematostella ve... 113 3e-24
UniRef50_Q3AQU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 112 6e-24
UniRef50_Q58424 Cluster: D-3-phosphoglycerate dehydrogenase; n=7... 111 1e-23
UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 110 2e-23
UniRef50_Q3ZX05 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 105 7e-22
UniRef50_Q7UQL2 Cluster: Phosphoglycerate dehydrogenase; n=2; Pl... 104 2e-21
UniRef50_Q9X1C1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 103 3e-21
UniRef50_A2U4T1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 103 4e-21
UniRef50_Q0W4A2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 103 5e-21
UniRef50_Q897N8 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 102 6e-21
UniRef50_A7HDB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 102 8e-21
UniRef50_A6C9V4 Cluster: Phosphoglycerate dehydrogenase; n=1; Pl... 101 1e-20
UniRef50_Q1IVI0 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 101 1e-20
UniRef50_A6UQN3 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 101 2e-20
UniRef50_P35136 Cluster: D-3-phosphoglycerate dehydrogenase; n=8... 101 2e-20
UniRef50_Q2AHU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 100 3e-20
UniRef50_A0L7J1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 100 3e-20
UniRef50_UPI0000E4762C Cluster: PREDICTED: similar to D-3-phosph... 99 4e-20
UniRef50_Q67TJ9 Cluster: Phosphoglycerate dehydrogenase; n=1; Sy... 99 8e-20
UniRef50_Q8PW48 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 99 8e-20
UniRef50_O29445 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 99 8e-20
UniRef50_Q1PZY1 Cluster: Similar to D-3-phosphoglycerate dehydro... 99 1e-19
UniRef50_A5UQ03 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 97 3e-19
UniRef50_A0LMX1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 96 5e-19
UniRef50_O04130 Cluster: D-3-phosphoglycerate dehydrogenase, chl... 95 1e-18
UniRef50_Q8TYK0 Cluster: Predicted dehydrogenase related to phos... 94 3e-18
UniRef50_Q1AXS3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 93 5e-18
UniRef50_A7CYD6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 93 7e-18
UniRef50_A6C2G1 Cluster: Phosphoglycerate dehydrogenase; n=1; Pl... 93 7e-18
UniRef50_A4FIF2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 93 7e-18
UniRef50_O33116 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 93 7e-18
UniRef50_UPI0000DC0E13 Cluster: 3-phosphoglycerate dehydrogenase... 92 1e-17
UniRef50_Q2LGV1 Cluster: Phosphoglycerate dehydrogenase; n=6; Ha... 92 1e-17
UniRef50_O67741 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 91 2e-17
UniRef50_A7P9P5 Cluster: Chromosome chr3 scaffold_8, whole genom... 91 2e-17
UniRef50_A1DFM4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 90 4e-17
UniRef50_Q8UJZ6 Cluster: Phosphoglycerate dehydrogenase; n=3; Al... 90 5e-17
UniRef50_Q8EN61 Cluster: Phosphoglycerate dehydrogenase; n=2; Ba... 90 5e-17
UniRef50_Q4L766 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 90 5e-17
UniRef50_P73821 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 90 5e-17
UniRef50_Q1NQ97 Cluster: D-isomer specific 2-hydroxyacid dehydro... 89 6e-17
UniRef50_A3EWA5 Cluster: Phosphoglycerate dehydrogenase; n=2; Ba... 88 1e-16
UniRef50_Q8R716 Cluster: Phosphoglycerate dehydrogenase and rela... 87 3e-16
UniRef50_Q8YIU3 Cluster: D-3-PHOSPHOGLYCERATE DEHYDROGENASE; n=7... 86 6e-16
UniRef50_A6PUG1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 85 1e-15
UniRef50_Q8EMJ8 Cluster: Hypothetical conserved protein; n=1; Oc... 85 1e-15
UniRef50_Q8ZTC7 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 84 3e-15
UniRef50_Q0EUV6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 83 4e-15
UniRef50_A0V9Y4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 83 4e-15
UniRef50_Q6MN05 Cluster: Phosphoglycerate dehydrogenase; n=1; Bd... 83 7e-15
UniRef50_Q0J5C2 Cluster: Os08g0447000 protein; n=11; Viridiplant... 82 9e-15
UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid ... 82 1e-14
UniRef50_A1HSQ7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 81 2e-14
UniRef50_Q9WYG2 Cluster: Phosphoglycerate dehydrogenase, putativ... 81 2e-14
UniRef50_Q7D366 Cluster: AGR_pAT_578p; n=2; Agrobacterium tumefa... 81 3e-14
UniRef50_A0UAW1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 81 3e-14
UniRef50_A0JVX0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 80 5e-14
UniRef50_Q9RUU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 79 7e-14
UniRef50_A6ULR7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 79 7e-14
UniRef50_Q97N23 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 79 9e-14
UniRef50_A4MA79 Cluster: D-isomer specific 2-hydroxyacid dehydro... 78 2e-13
UniRef50_Q8XPB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 78 2e-13
UniRef50_A4YUP8 Cluster: Putative D-3-phosphoglycerate dehydroge... 78 2e-13
UniRef50_A1IDH6 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 78 2e-13
UniRef50_Q5WLJ2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 77 3e-13
UniRef50_A6DQ00 Cluster: SerA; n=1; Lentisphaera araneosa HTCC21... 77 4e-13
UniRef50_Q18XF4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 77 5e-13
UniRef50_A1RDF9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 77 5e-13
UniRef50_Q88ZU6 Cluster: Phosphoglycerate dehydrogenase; n=2; La... 76 6e-13
UniRef50_Q46VE6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 76 6e-13
UniRef50_Q6W1I8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 75 1e-12
UniRef50_Q0K073 Cluster: D-3-Phosphoglycerate dehydrogenase; n=2... 73 4e-12
UniRef50_A7HEG1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 6e-12
UniRef50_A6Q7Q2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 73 6e-12
UniRef50_A5URV2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 72 1e-11
UniRef50_Q81T55 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 2e-11
UniRef50_Q031D4 Cluster: Phosphoglycerate dehydrogenase; n=20; S... 71 2e-11
UniRef50_Q3KBX8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 3e-11
UniRef50_Q21A61 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 3e-11
UniRef50_Q0FX01 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 3e-11
UniRef50_A7CY19 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 3e-11
UniRef50_A6UCB8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 3e-11
UniRef50_A6CKS4 Cluster: Putative uncharacterized protein; n=1; ... 71 3e-11
UniRef50_A7HM61 Cluster: Glyoxylate reductase; n=1; Fervidobacte... 70 4e-11
UniRef50_A4WXD4 Cluster: Dimethylmenaquinone methyltransferase; ... 70 5e-11
UniRef50_Q3CIY1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 7e-11
UniRef50_Q03YV3 Cluster: Lactate dehydrogenase related enzyme; n... 69 7e-11
UniRef50_A7NGZ0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 7e-11
UniRef50_Q5KN70 Cluster: D-3-phosphoglycerate dehydrogenase 2, p... 69 7e-11
UniRef50_A1AR04 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 9e-11
UniRef50_O86322 Cluster: POSSIBLE D-3-PHOSPHOGLYCERATE DEHYDROGE... 69 1e-10
UniRef50_A1W9A3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 1e-10
UniRef50_A0JWH0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 1e-10
UniRef50_Q8Y3L1 Cluster: Lmo2824 protein; n=14; Bacillales|Rep: ... 68 2e-10
UniRef50_Q3SK87 Cluster: D-isomer specific 2-hydroxyacid dehydro... 68 2e-10
UniRef50_Q0RXU8 Cluster: Phosphoglycerate dehydrogenase; n=1; Rh... 68 2e-10
UniRef50_Q4WHR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 68 2e-10
UniRef50_Q97ZK1 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 68 2e-10
UniRef50_A4YFM2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 68 2e-10
UniRef50_Q825H6 Cluster: Putative glycerate dehydrogenase; n=1; ... 68 2e-10
UniRef50_A4FHH0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 68 2e-10
UniRef50_Q1CG62 Cluster: D-isomer specific 2-hydroxyacid dehydro... 67 3e-10
UniRef50_A6T665 Cluster: Putative D-3-phosphoglycerate dehydroge... 67 3e-10
UniRef50_A4FK85 Cluster: D-3-phosphoglycerate dehydrogenase, put... 67 3e-10
UniRef50_A0RW58 Cluster: Phosphoglycerate dehydrogenase; n=3; Cr... 67 3e-10
UniRef50_Q74CK1 Cluster: Glycerate dehydrogenase; n=12; Bacteria... 67 4e-10
UniRef50_Q39LG4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 67 4e-10
UniRef50_Q0ETU3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 67 4e-10
UniRef50_A7CR80 Cluster: D-isomer specific 2-hydroxyacid dehydro... 67 4e-10
UniRef50_A4FIJ9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 67 4e-10
UniRef50_A5V6T9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 5e-10
UniRef50_O28495 Cluster: 2-hydroxyacid dehydrogenase, putative; ... 66 5e-10
UniRef50_UPI000050F9E4 Cluster: COG0111: Phosphoglycerate dehydr... 66 9e-10
UniRef50_Q82XE1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 9e-10
UniRef50_A3ZW64 Cluster: Phosphoglycerate dehydrogenase, putativ... 66 9e-10
UniRef50_A1G3C5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 9e-10
UniRef50_Q7WM64 Cluster: Putative dehydrogenase; n=2; Bordetella... 65 1e-09
UniRef50_A4TF35 Cluster: D-isomer specific 2-hydroxyacid dehydro... 65 1e-09
UniRef50_A1HMI9 Cluster: Phosphoglycerate dehydrogenase; n=1; Th... 65 1e-09
UniRef50_P13443 Cluster: Glycerate dehydrogenase; n=15; Viridipl... 65 1e-09
UniRef50_Q65WI5 Cluster: SerA protein; n=1; Mannheimia succinici... 65 2e-09
UniRef50_Q49ZM5 Cluster: Putative dehydrogenase; n=1; Staphyloco... 65 2e-09
UniRef50_O34815 Cluster: YoaD; n=2; Bacillus|Rep: YoaD - Bacillu... 65 2e-09
UniRef50_A6EBH4 Cluster: Phosphoglycerate dehydrogenase; n=1; Pe... 65 2e-09
UniRef50_Q82U25 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 2e-09
UniRef50_A1JTE6 Cluster: Putative oxidoreductase; n=1; Yersinia ... 64 2e-09
UniRef50_Q0W672 Cluster: Glycerate dehydrogenase; n=2; Archaea|R... 64 2e-09
UniRef50_A0RUD3 Cluster: 2 lactate dehydrogenase; n=2; Thermopro... 64 2e-09
UniRef50_Q8EP33 Cluster: Glycerate dehydrogenase; n=2; Bacillace... 64 3e-09
UniRef50_Q81N95 Cluster: D-3-phosphoglycerate dehydrogenase, put... 64 3e-09
UniRef50_A4S3N1 Cluster: Predicted protein; n=2; Ostreococcus|Re... 64 3e-09
UniRef50_Q5FUW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 63 5e-09
UniRef50_Q04DF1 Cluster: Lactate dehydrogenase related enzyme; n... 63 5e-09
UniRef50_A4EAR0 Cluster: Putative uncharacterized protein; n=1; ... 63 5e-09
UniRef50_A1HM37 Cluster: D-isomer specific 2-hydroxyacid dehydro... 63 5e-09
UniRef50_Q986P2 Cluster: Phosphoglycerate dehydrogenase; n=14; c... 63 6e-09
UniRef50_Q8R8Q2 Cluster: Lactate dehydrogenase and related dehyd... 63 6e-09
UniRef50_Q88YI0 Cluster: Phosphoglycerate dehydrogenase; n=5; Ba... 63 6e-09
UniRef50_Q72KT6 Cluster: Glycerate dehydrogenase/glyoxylate redu... 63 6e-09
UniRef50_A6PPS4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 63 6e-09
UniRef50_Q6MY49 Cluster: NAD-dependant D-isomer specific 2-hydro... 63 6e-09
UniRef50_Q1WVK4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 62 8e-09
UniRef50_O58320 Cluster: Glyoxylate reductase; n=16; cellular or... 62 8e-09
UniRef50_Q83AZ4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 1e-08
UniRef50_Q6F7L0 Cluster: Glycerate dehydrogenase; n=3; Gammaprot... 62 1e-08
UniRef50_Q6A5K9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 1e-08
UniRef50_Q11JH0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 1e-08
UniRef50_A3PPC6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 1e-08
UniRef50_A1W7V5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 1e-08
UniRef50_Q6L245 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 62 1e-08
UniRef50_Q3Y1E6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 1e-08
UniRef50_Q1MQK2 Cluster: Phosphoglycerate dehydrogenase and rela... 62 1e-08
UniRef50_Q8CPW2 Cluster: Glycerate dehydrogenase; n=4; Staphyloc... 61 2e-08
UniRef50_Q89QF5 Cluster: Blr3173 protein; n=3; Bradyrhizobium|Re... 61 3e-08
UniRef50_Q2S4U0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 3e-08
UniRef50_A6C853 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 61 3e-08
UniRef50_A0ZEB8 Cluster: Predicted dehydrogenase; n=6; Cyanobact... 61 3e-08
UniRef50_Q27SS3 Cluster: Glycerate dehydrogenase-like protein; n... 61 3e-08
UniRef50_UPI000023F60F Cluster: hypothetical protein FG08018.1; ... 60 3e-08
UniRef50_Q7X388 Cluster: Phosphoglycerate dehydrogenase; n=3; Es... 60 3e-08
UniRef50_Q44NM9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 60 3e-08
UniRef50_A6LZ51 Cluster: D-isomer specific 2-hydroxyacid dehydro... 60 3e-08
UniRef50_A4EQ78 Cluster: Dehydrogenase; n=1; Roseobacter sp. SK2... 60 3e-08
UniRef50_A3JX80 Cluster: D-isomer specific 2-hydroxyacid dehydro... 60 3e-08
UniRef50_A4RX85 Cluster: Predicted protein; n=3; Ostreococcus|Re... 60 4e-08
UniRef50_Q1K3M3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 60 6e-08
UniRef50_Q03WU1 Cluster: Lactate dehydrogenase related dehydroge... 60 6e-08
UniRef50_A6GGA6 Cluster: Probable 2-hydroxyacid dehydrogenase; n... 60 6e-08
UniRef50_A7P8C8 Cluster: Chromosome chr3 scaffold_8, whole genom... 60 6e-08
UniRef50_A2SRM1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 60 6e-08
UniRef50_P40054 Cluster: D-3-phosphoglycerate dehydrogenase 1; n... 60 6e-08
UniRef50_UPI00015BD3AA Cluster: UPI00015BD3AA related cluster; n... 59 8e-08
UniRef50_Q7UQC8 Cluster: Probable 2-hydroxyacid dehydrogenase; n... 59 8e-08
UniRef50_Q11UL6 Cluster: Phosphoglycerate dehydrogenase; n=1; Cy... 59 8e-08
UniRef50_Q01W77 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 8e-08
UniRef50_A6G5P3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 59 8e-08
UniRef50_A5Z3X2 Cluster: Putative uncharacterized protein; n=1; ... 59 8e-08
UniRef50_Q9TXJ5 Cluster: D-3-phosphoglycerate dehydrogenase-like... 59 8e-08
UniRef50_A3H6F3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 8e-08
UniRef50_Q4AIL7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 1e-07
UniRef50_Q214B1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 1e-07
UniRef50_A6CRV0 Cluster: 2-hydroxyacid dehydrogenase; n=15; Baci... 59 1e-07
UniRef50_A0VQR0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 1e-07
UniRef50_Q63VJ5 Cluster: D-3-phosphoglycerate dehydrogenase; n=8... 58 1e-07
UniRef50_Q5KYJ7 Cluster: Dehydrogenase; n=3; Firmicutes|Rep: Deh... 58 1e-07
UniRef50_Q2NVC4 Cluster: Putative 2-hydroxyacid-family dehydroge... 58 1e-07
UniRef50_A3K878 Cluster: 2-hydroxyacid dehydrogenase; n=1; Sagit... 58 1e-07
UniRef50_Q7NEV2 Cluster: Phosphoglycerate dehydrogenase; n=6; Ba... 58 2e-07
UniRef50_Q2S4S4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 58 2e-07
UniRef50_Q1FF19 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 2e-07
UniRef50_A7IJ69 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 2e-07
UniRef50_A1UEI9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 2e-07
UniRef50_Q896Z8 Cluster: 2-hydroxyacid dehydrogenase; n=4; Clost... 58 2e-07
UniRef50_P73990 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 2e-07
UniRef50_Q4IV69 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 2e-07
UniRef50_Q0FY56 Cluster: Putative phosphoglycerate dehydrogenase... 58 2e-07
UniRef50_Q4WMF4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 2e-07
UniRef50_Q9HK29 Cluster: 2-hydroxyacid dehydrogenase related pro... 58 2e-07
UniRef50_Q5FUD9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 57 3e-07
UniRef50_Q1LCR9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 57 3e-07
UniRef50_Q126V3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 57 3e-07
UniRef50_A4AN91 Cluster: Predicted dehydrogenase; n=14; Bacteroi... 57 3e-07
UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid dehydro... 57 4e-07
UniRef50_Q125T3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 57 4e-07
UniRef50_A1HQU2 Cluster: Glyoxylate reductase; n=1; Thermosinus ... 57 4e-07
UniRef50_A0HBX6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 57 4e-07
UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 56 5e-07
UniRef50_A2QX18 Cluster: Contig An11c0250, complete genome; n=3;... 56 5e-07
UniRef50_Q8TR50 Cluster: Glycerate dehydrogenase; n=2; Methanosa... 56 5e-07
UniRef50_A1S0J0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 5e-07
UniRef50_P0A9T3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 56 5e-07
UniRef50_Q6FCL4 Cluster: 2-keto-D-gluconate reductase; n=15; Pse... 56 9e-07
UniRef50_A7HBU0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 9e-07
UniRef50_Q931A1 Cluster: Putative; n=2; Rhizobiales|Rep: Putativ... 55 1e-06
UniRef50_Q89EL0 Cluster: Blr7063 protein; n=1; Bradyrhizobium ja... 55 1e-06
UniRef50_Q0B1Q1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 55 1e-06
UniRef50_A2A023 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 55 1e-06
UniRef50_Q5KQ73 Cluster: D-3-phosphoglycerate dehydrogenase, put... 55 1e-06
UniRef50_Q0CUD5 Cluster: Putative uncharacterized protein; n=1; ... 55 1e-06
UniRef50_Q6A895 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 55 2e-06
UniRef50_Q5FKH9 Cluster: Glyoxylate reductase; n=1; Lactobacillu... 55 2e-06
UniRef50_Q2LUG0 Cluster: 2-hydroxyacid dehydrogenase, D-isomer s... 55 2e-06
UniRef50_A4ARG6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 55 2e-06
UniRef50_A0LN07 Cluster: D-isomer specific 2-hydroxyacid dehydro... 55 2e-06
UniRef50_A0GDF1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 2e-06
UniRef50_A7EUN0 Cluster: Formate dehydrogenase; n=2; Sclerotinia... 54 2e-06
UniRef50_Q5BU19 Cluster: Ribeye a protein; n=4; Clupeocephala|Re... 54 3e-06
UniRef50_Q6AMI7 Cluster: Related to D-3-phosphoglycerate dehydro... 54 3e-06
UniRef50_A1RC54 Cluster: Glyoxylate reductase; n=2; Actinomyceta... 54 3e-06
UniRef50_A1AQ02 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 3e-06
UniRef50_Q27SN5 Cluster: Beta xylosidase-like protein; n=1; Acan... 54 3e-06
UniRef50_Q5LQR6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 4e-06
UniRef50_Q1GJ08 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 4e-06
UniRef50_A5N5A9 Cluster: SerA; n=1; Clostridium kluyveri DSM 555... 54 4e-06
UniRef50_A4AQJ2 Cluster: D-lactate dehydrogenase; n=1; Flavobact... 54 4e-06
UniRef50_A0Z6W9 Cluster: Spermidine/putrescine ABC transporter A... 54 4e-06
UniRef50_Q11JF3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 5e-06
UniRef50_A1ZGW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 53 5e-06
UniRef50_Q5KE95 Cluster: Phosphoglycerate dehydrogenase; n=2; Fi... 53 5e-06
UniRef50_Q8YEC6 Cluster: Gluconate 2-dehydrogenase; n=72; Alphap... 53 7e-06
UniRef50_Q89LI6 Cluster: Blr4558 protein; n=6; Bradyrhizobiaceae... 53 7e-06
UniRef50_Q3A6W9 Cluster: 3-phosphoglycerate dehydrogenase; n=1; ... 53 7e-06
UniRef50_Q397E0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 7e-06
UniRef50_Q4IXK9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 7e-06
UniRef50_Q3DL54 Cluster: Glyoxylate reductase, NADH-dependent; n... 53 7e-06
UniRef50_A4A9T4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 7e-06
UniRef50_Q59516 Cluster: Glycerate dehydrogenase; n=23; Proteoba... 53 7e-06
UniRef50_Q9K7P7 Cluster: Glycerate dehydrogenase; n=8; Bacillace... 52 9e-06
UniRef50_Q9HVG5 Cluster: Glycerate dehydrogenase; n=23; Gammapro... 52 9e-06
UniRef50_Q89J71 Cluster: 2-hydroxyacid dehydrogenase; n=8; Brady... 52 9e-06
UniRef50_Q5LT44 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 9e-06
UniRef50_Q49UN3 Cluster: NAD-dependent formate dehydrogenase; n=... 52 9e-06
UniRef50_Q03U10 Cluster: 2-hydroxyacid dehydrogenase; n=1; Lacto... 52 9e-06
UniRef50_Q5KFZ5 Cluster: Phosphoglycerate dehydrogenase, putativ... 52 9e-06
UniRef50_Q2UDC2 Cluster: Glyoxylate/hydroxypyruvate reductase; n... 52 9e-06
UniRef50_A0YEL9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 1e-05
UniRef50_A0FZA8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 1e-05
UniRef50_O50096 Cluster: Putative uncharacterized protein PH1388... 52 1e-05
UniRef50_P17584 Cluster: D-2-hydroxyisocaproate dehydrogenase; n... 52 1e-05
UniRef50_P44501 Cluster: 2-hydroxyacid dehydrogenase homolog; n=... 52 1e-05
UniRef50_P56545 Cluster: C-terminal-binding protein 2; n=98; Coe... 52 1e-05
UniRef50_UPI0000DA2A77 Cluster: PREDICTED: similar to D-3-phosph... 52 2e-05
UniRef50_Q398N2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 2e-05
UniRef50_A4ETV8 Cluster: Putative uncharacterized protein; n=6; ... 52 2e-05
UniRef50_A0Z2L3 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05
UniRef50_A0L0H4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 2e-05
UniRef50_Q5V1E2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 52 2e-05
UniRef50_Q3KAR6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 51 2e-05
UniRef50_Q1GAM7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 51 2e-05
UniRef50_Q20595 Cluster: Putative uncharacterized protein; n=3; ... 51 2e-05
UniRef50_P52643 Cluster: D-lactate dehydrogenase; n=118; cellula... 51 2e-05
UniRef50_Q64UR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 51 3e-05
UniRef50_Q1VRN5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 51 3e-05
UniRef50_Q126C0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 51 3e-05
UniRef50_Q11QU3 Cluster: D-lactate dehydrogenase; n=1; Cytophaga... 51 3e-05
UniRef50_Q0C254 Cluster: D-isomer specific 2-hydroxyacid dehydro... 51 3e-05
UniRef50_A6FZB7 Cluster: Putative dehydrogenase; n=1; Plesiocyst... 51 3e-05
UniRef50_UPI000023EBBC Cluster: hypothetical protein FG00146.1; ... 50 4e-05
UniRef50_A7HWK6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 50 4e-05
UniRef50_A5UPU9 Cluster: Glyoxylate reductase; n=12; Bacteria|Re... 50 4e-05
UniRef50_A4AL46 Cluster: Putative dehydrogenase; n=1; marine act... 50 4e-05
UniRef50_A0Y9Y1 Cluster: Glyoxylate reductase; n=2; unclassified... 50 4e-05
UniRef50_Q9KEA4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 50 5e-05
UniRef50_Q5FTU6 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 50 5e-05
UniRef50_Q7WNI7 Cluster: Putative dehydrogenase; n=1; Bordetella... 50 6e-05
UniRef50_A6W9Y4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 50 6e-05
UniRef50_A3VA29 Cluster: D-isomer specific 2-hydroxyacid dehydro... 50 6e-05
UniRef50_A3RV54 Cluster: 2-hydroxyacid dehydrogenase; n=5; Burkh... 50 6e-05
UniRef50_A3IA61 Cluster: D-3 phosphoglycerate dehydrogenase; n=1... 50 6e-05
UniRef50_Q97F10 Cluster: Possible phosphoglycerate dehydrogenase... 49 8e-05
UniRef50_Q65DI9 Cluster: YoaD; n=1; Bacillus licheniformis ATCC ... 49 8e-05
UniRef50_Q0LSC3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 8e-05
UniRef50_A4SWE6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 8e-05
UniRef50_A0Q8P3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 8e-05
UniRef50_Q7WEA3 Cluster: Phosphoglycerate dehydrogenase; n=1; Bo... 49 1e-04
UniRef50_Q7MT26 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 1e-04
UniRef50_Q3S8E5 Cluster: Putative D-isomer specific 2-hydroxyaci... 49 1e-04
UniRef50_Q1MPI0 Cluster: Lactate dehydrogenase and related dehyd... 49 1e-04
UniRef50_A5G0Z0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 1e-04
UniRef50_A1WHT1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 1e-04
UniRef50_Q752A0 Cluster: AFR675Wp; n=3; Saccharomycetales|Rep: A... 49 1e-04
UniRef50_Q7W397 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 48 1e-04
UniRef50_Q67M76 Cluster: Phosphoglycerate dehydrogenase, N-termi... 48 1e-04
UniRef50_A5P5Y8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 1e-04
UniRef50_A2SEV8 Cluster: Phosphoglycerate dehydrogenase-related ... 48 1e-04
UniRef50_Q7X9L3 Cluster: Formate dehydrogenase; n=4; Magnoliophy... 48 1e-04
UniRef50_Q8EMJ4 Cluster: 2-ketogluconate reductase; n=1; Oceanob... 48 2e-04
UniRef50_Q12CS0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 2e-04
UniRef50_Q04AA8 Cluster: Lactate dehydrogenase related enzyme; n... 48 2e-04
UniRef50_A5ZA39 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04
UniRef50_Q9UYH9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 2e-04
UniRef50_Q9K1Q1 Cluster: Glycerate dehydrogenase; n=6; cellular ... 48 2e-04
UniRef50_Q4FNZ3 Cluster: Probable dehydrogenase; n=2; Candidatus... 48 2e-04
UniRef50_Q0FF66 Cluster: Glycolate reductase; n=2; Alphaproteoba... 48 2e-04
UniRef50_A7FYM9 Cluster: D-lactate dehydrogenase; n=4; Clostridi... 48 2e-04
UniRef50_A5G1C9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 2e-04
UniRef50_Q5KKI9 Cluster: 2-hydroxyacid dehydrogenase, putative; ... 48 2e-04
UniRef50_O94574 Cluster: Putative 2-hydroxyacid dehydrogenase C1... 48 2e-04
UniRef50_P36234 Cluster: Glycerate dehydrogenase; n=2; Hyphomicr... 48 2e-04
UniRef50_Q62LV8 Cluster: Glyoxylate reductase; n=53; cellular or... 47 3e-04
UniRef50_Q2KZD5 Cluster: Putative reductase precursor; n=1; Bord... 47 3e-04
UniRef50_A5VE25 Cluster: D-isomer specific 2-hydroxyacid dehydro... 47 3e-04
UniRef50_Q0CK41 Cluster: Putative uncharacterized protein; n=5; ... 47 3e-04
UniRef50_A5YST2 Cluster: Phosphoglycerate dehydrogenase; n=2; Ha... 47 3e-04
UniRef50_P58220 Cluster: 2-ketogluconate reductase; n=75; Proteo... 47 3e-04
UniRef50_UPI0000D9FBAD Cluster: PREDICTED: similar to 3-phosphog... 47 4e-04
UniRef50_Q6FFP8 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 47 4e-04
UniRef50_Q4PK14 Cluster: Predicted D-isomer specific 2-hydroxyac... 47 4e-04
UniRef50_A4BPX8 Cluster: Glycerate dehydrogenase; n=1; Nitrococc... 47 4e-04
UniRef50_A0NLL6 Cluster: Glycerate dehydrogenase; n=1; Stappia a... 47 4e-04
UniRef50_Q0D7C9 Cluster: Os07g0264100 protein; n=5; Oryza sativa... 47 4e-04
UniRef50_A5BY55 Cluster: Putative uncharacterized protein; n=2; ... 47 4e-04
UniRef50_Q4PP80 Cluster: Putative glyoxylate reductase/hydroxypy... 47 4e-04
UniRef50_Q12VM6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 47 4e-04
UniRef50_Q8YK31 Cluster: Glycerate dehydrogenase; n=3; Cyanobact... 46 6e-04
UniRef50_Q8F5N8 Cluster: Phosphoglycerate dehydrogenase; n=4; Le... 46 6e-04
UniRef50_Q5HW94 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 6e-04
UniRef50_Q483F8 Cluster: Putative glyoxylate reductase; n=1; Col... 46 6e-04
UniRef50_Q9LE33 Cluster: T12C24.9; n=6; core eudicotyledons|Rep:... 46 6e-04
UniRef50_Q8LL97 Cluster: Putative uncharacterized protein; n=1; ... 46 6e-04
UniRef50_A4R4W0 Cluster: Formate dehydrogenase; n=1; Magnaporthe... 46 6e-04
UniRef50_A4QT80 Cluster: Putative uncharacterized protein; n=2; ... 46 6e-04
UniRef50_UPI00015B49ED Cluster: PREDICTED: similar to putative g... 46 8e-04
UniRef50_Q12E23 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 8e-04
UniRef50_Q120R1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 8e-04
UniRef50_Q0PQJ5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 8e-04
UniRef50_A4SW26 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 8e-04
UniRef50_Q6CDS0 Cluster: Similar to tr|O94020 Candida albicans Y... 46 8e-04
UniRef50_UPI000038E31A Cluster: hypothetical protein Faci_030017... 46 0.001
UniRef50_Q8U6W5 Cluster: 2-hydroxyacid dehydrogenase; n=3; Alpha... 46 0.001
UniRef50_Q8G427 Cluster: Possible 2-hydroxyacid dehydrogenase; n... 46 0.001
UniRef50_Q8EMM3 Cluster: Dehydrogenase; n=2; cellular organisms|... 46 0.001
UniRef50_Q579J7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_Q39JN8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_Q1V097 Cluster: Phosphoglycerate dehydrogenase; n=2; Ca... 46 0.001
UniRef50_A5ZQ76 Cluster: Putative uncharacterized protein; n=2; ... 46 0.001
UniRef50_A1SPF8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_A1BC99 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_Q2RTD0 Cluster: Glycolate reductase; n=8; Alphaproteoba... 45 0.001
UniRef50_A0QQ27 Cluster: Glyoxylate reductase; n=4; Mycobacteriu... 45 0.001
UniRef50_A7I9X3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 45 0.001
UniRef50_Q1M6M5 Cluster: Putative glyoxylate reductase; n=1; Rhi... 45 0.002
UniRef50_Q6BTY7 Cluster: Debaryomyces hansenii chromosome C of s... 45 0.002
UniRef50_Q9S2M5 Cluster: Putative D-lactate dehydrogenase; n=1; ... 44 0.002
UniRef50_A7BQE7 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 44 0.002
UniRef50_A2F8V0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.002
UniRef50_Q6LYW5 Cluster: 2-hydroxyacid dehydrogenase, D-isomer s... 44 0.002
UniRef50_A4TXP1 Cluster: Glycolate reductase; n=1; Magnetospiril... 44 0.003
UniRef50_Q7MV92 Cluster: Glycerate dehydrogenase; n=1; Porphyrom... 44 0.004
UniRef50_Q63YS2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.004
UniRef50_Q11AM6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.004
UniRef50_A4U158 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.004
UniRef50_A1WAF9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.004
UniRef50_A0PVI8 Cluster: D-3-phosphoglycerate dehydrogenase SerA... 44 0.004
UniRef50_Q8VX85 Cluster: Putative NAD-dependent formate dehydrog... 44 0.004
UniRef50_Q22CX9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.004
UniRef50_A4R1I1 Cluster: Putative uncharacterized protein; n=1; ... 44 0.004
UniRef50_O69054 Cluster: Phosphonate dehydrogenase; n=16; Bacter... 44 0.004
UniRef50_Q82XY9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 43 0.005
UniRef50_Q120S8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 43 0.005
UniRef50_A6TVU1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 43 0.005
UniRef50_A3ZMM2 Cluster: Dehydrogenase; n=1; Blastopirellula mar... 43 0.005
UniRef50_Q76KF5 Cluster: D-phosphoglycerate dehydrogenase; n=2; ... 43 0.005
UniRef50_Q8ZXX8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 43 0.005
UniRef50_Q59642 Cluster: D-lactate dehydrogenase; n=5; Pediococc... 43 0.005
UniRef50_Q88VJ2 Cluster: D-lactate dehydrogenase; n=27; Lactobac... 43 0.005
UniRef50_Q6MIG3 Cluster: Hxdroxypyruvate reductase; n=1; Bdellov... 43 0.007
UniRef50_Q2CCV7 Cluster: Putative uncharacterized protein; n=1; ... 43 0.007
UniRef50_A7AAD2 Cluster: Putative uncharacterized protein; n=1; ... 43 0.007
UniRef50_A7S382 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 43 0.007
UniRef50_Q6KZ29 Cluster: Gluconate 2-dehydrogenase; n=3; Archaea... 43 0.007
UniRef50_O66939 Cluster: D-lactate dehydrogenase; n=1; Aquifex a... 42 0.009
UniRef50_Q2B326 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 42 0.009
UniRef50_Q13ZE9 Cluster: Putative dehydrogenase, D-3-phosphoglyc... 42 0.009
UniRef50_A6Q6K4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.009
UniRef50_A5VEE7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.009
UniRef50_Q8MR05 Cluster: LD48009p; n=11; Coelomata|Rep: LD48009p... 42 0.009
UniRef50_A7D498 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.009
UniRef50_Q99ZM2 Cluster: D-lactate dehydrogenase; n=7; Streptoco... 42 0.009
UniRef50_Q5WAF3 Cluster: 2-ketogluconate reductase; n=1; Bacillu... 42 0.012
UniRef50_Q397D5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.012
UniRef50_Q8GQX5 Cluster: 2-oxo-4-phenylbutanoate reductase; n=2;... 42 0.012
UniRef50_A6W4F1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.012
UniRef50_A6DPW5 Cluster: 2-hydroxyacid-family dehydrogenase; n=2... 42 0.012
UniRef50_Q1E5G6 Cluster: Putative uncharacterized protein; n=1; ... 42 0.012
UniRef50_O32264 Cluster: Probable 2-ketogluconate reductase; n=1... 42 0.012
UniRef50_Q036G7 Cluster: Lactate dehydrogenase related 2-hydroxy... 42 0.016
UniRef50_A7CWK1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.016
UniRef50_Q1E2M0 Cluster: Putative uncharacterized protein; n=3; ... 42 0.016
UniRef50_A6QVW0 Cluster: Putative uncharacterized protein; n=1; ... 42 0.016
UniRef50_Q8RC97 Cluster: Phosphoglycerate dehydrogenase and rela... 41 0.022
UniRef50_Q3KE30 Cluster: D-isomer specific 2-hydroxyacid dehydro... 41 0.022
UniRef50_Q3IFC5 Cluster: 2-hydroxyacid dehydrogenase family prot... 41 0.022
UniRef50_A5ZAJ9 Cluster: Putative uncharacterized protein; n=1; ... 41 0.022
UniRef50_A3PDQ1 Cluster: Putative dehydrogenase; n=1; Prochloroc... 41 0.022
UniRef50_A1FGW0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 41 0.022
UniRef50_Q883D2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 41 0.029
UniRef50_Q1LFJ5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 41 0.029
UniRef50_A6CXX0 Cluster: Dehydrogenase; n=1; Vibrio shilonii AK1... 41 0.029
UniRef50_A5N6P2 Cluster: GyaR; n=1; Clostridium kluyveri DSM 555... 41 0.029
UniRef50_A4M784 Cluster: D-isomer specific 2-hydroxyacid dehydro... 41 0.029
UniRef50_Q8H423 Cluster: Putative phosphoglycerate dehydrogenase... 41 0.029
UniRef50_Q5K657 Cluster: Hydroxyacid dehydrogenase protein Ynl27... 41 0.029
UniRef50_O14075 Cluster: Putative 2-hydroxyacid dehydrogenase UN... 41 0.029
UniRef50_Q9KP72 Cluster: 2-hydroxyacid dehydrogenase family prot... 40 0.038
UniRef50_Q8ES01 Cluster: Dehydrogenase; n=4; Bacillaceae|Rep: De... 40 0.038
UniRef50_Q73M93 Cluster: Glycerate dehydrogenase; n=3; Bacteria|... 40 0.038
UniRef50_Q5LSR6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.038
UniRef50_Q47W88 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.038
UniRef50_Q2BHH2 Cluster: Glycerate dehydrogenase; n=1; Neptuniib... 40 0.038
UniRef50_A5MYX9 Cluster: Putative uncharacterized protein; n=1; ... 40 0.038
UniRef50_A3JTB6 Cluster: Putative D-isomer specific 2-hydroxyaci... 40 0.038
UniRef50_A1GFX2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.038
UniRef50_A0YGL0 Cluster: Dehydrogenase; n=1; marine gamma proteo... 40 0.038
UniRef50_A0R5A8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.038
UniRef50_Q6NUX3 Cluster: Im:7137941 protein; n=3; Danio rerio|Re... 40 0.050
UniRef50_Q9RJW2 Cluster: Possible 2-hydroxyacid-family dehydroge... 40 0.050
UniRef50_Q5QU97 Cluster: 2-hydroxyacid dehydrogenase; n=4; Gamma... 40 0.050
UniRef50_Q03XJ7 Cluster: 2-hydroxyacid dehydrogenase; n=3; Lacto... 40 0.050
UniRef50_A6BZW2 Cluster: Putative dehydrogenase; n=1; Planctomyc... 40 0.050
UniRef50_A4BI79 Cluster: D-lactate dehydrogenase; n=1; Reinekea ... 40 0.050
UniRef50_Q4SJ39 Cluster: Chromosome 21 SCAF14577, whole genome s... 40 0.066
UniRef50_Q9RJA1 Cluster: Putative 2-hydroxyacid-family dehydroge... 40 0.066
UniRef50_Q8XN08 Cluster: D-lactate dehydrogenase; n=4; Firmicute... 40 0.066
UniRef50_Q81K70 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.066
UniRef50_Q5IW39 Cluster: Putative PhpE; n=2; Actinomycetales|Rep... 40 0.066
UniRef50_Q2AHD3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.066
UniRef50_Q120Q8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.066
UniRef50_A5KMM3 Cluster: Putative uncharacterized protein; n=1; ... 40 0.066
UniRef50_A3XKE7 Cluster: D-lactate dehydrogenase; n=3; Bacteria|... 40 0.066
UniRef50_A7PQ72 Cluster: Chromosome chr18 scaffold_24, whole gen... 40 0.066
UniRef50_Q5KJK5 Cluster: Glycerate-and formate-dehydrogenase, pu... 40 0.066
UniRef50_Q4P752 Cluster: Putative uncharacterized protein; n=1; ... 40 0.066
UniRef50_Q98GE4 Cluster: Phosphoglycerate dehydrogenase; n=5; Rh... 39 0.088
UniRef50_Q87JV4 Cluster: D-lactate dehydrogenase; n=6; Vibrio|Re... 39 0.088
UniRef50_Q11SX0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 39 0.088
UniRef50_Q0RPA4 Cluster: Putative D-isomer specific 2-hydroxyaci... 39 0.088
UniRef50_Q0HS14 Cluster: D-isomer specific 2-hydroxyacid dehydro... 39 0.088
UniRef50_Q08911 Cluster: Formate dehydrogenase 1; n=71; Eukaryot... 39 0.088
UniRef50_Q82W00 Cluster: D-isomer specific 2-hydroxyacid dehydro... 39 0.12
UniRef50_Q01QI5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 39 0.12
UniRef50_A5WBM9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 39 0.12
UniRef50_UPI0000383A41 Cluster: COG1052: Lactate dehydrogenase a... 38 0.15
UniRef50_Q0RXQ1 Cluster: Probable phosphoglycerate dehydrogenase... 38 0.15
UniRef50_A1ZX42 Cluster: Glycerate dehydrogenase; n=1; Microscil... 38 0.15
UniRef50_A1HMH1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 38 0.15
UniRef50_Q4PER7 Cluster: Putative uncharacterized protein; n=1; ... 38 0.15
UniRef50_UPI00015B4C72 Cluster: PREDICTED: similar to ENSANGP000... 38 0.20
UniRef50_Q026D8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 38 0.20
UniRef50_A5ZAS1 Cluster: Putative uncharacterized protein; n=1; ... 38 0.20
UniRef50_Q1QXV7 Cluster: Erythronate-4-phosphate dehydrogenase; ... 38 0.20
UniRef50_Q3M599 Cluster: D-isomer specific 2-hydroxyacid dehydro... 38 0.27
UniRef50_Q5U922 Cluster: (R)-2-hydroxyisocaproate dehydrogenase;... 38 0.27
UniRef50_Q1ASE8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 38 0.27
UniRef50_Q893I3 Cluster: D-lactate dehydrogenase; n=2; Firmicute... 37 0.35
UniRef50_Q67ME2 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 37 0.35
UniRef50_Q6RK69 Cluster: D-lactate dehydrogenase; n=1; Lactobaci... 37 0.35
UniRef50_Q1IPG3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 37 0.35
UniRef50_A5TSY9 Cluster: Possible dehydrogenase; n=1; Fusobacter... 37 0.35
UniRef50_O83080 Cluster: D-lactate dehydrogenase; n=1; Treponema... 37 0.35
UniRef50_UPI000155367B Cluster: PREDICTED: hypothetical protein;... 37 0.47
UniRef50_UPI0000384B5F Cluster: COG0111: Phosphoglycerate dehydr... 37 0.47
UniRef50_A6UHC3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 37 0.47
UniRef50_A5V093 Cluster: D-isomer specific 2-hydroxyacid dehydro... 37 0.47
UniRef50_Q5UZP4 Cluster: Phosphoglycerate dehydrogenase; n=2; Ha... 37 0.47
UniRef50_Q7M7Q8 Cluster: PUTATIVE D-2-HYDROXYACID DEHYDROGENASE;... 36 0.62
UniRef50_Q5NR73 Cluster: 2-hydroxyacid dehydrogenase; n=1; Zymom... 36 0.62
UniRef50_A5KSE5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 36 0.62
UniRef50_Q9HSS1 Cluster: Phosphoglycerate dehydrogenase; n=1; Ha... 36 0.62
UniRef50_Q8FPW0 Cluster: Putative uncharacterized protein; n=1; ... 36 0.82
UniRef50_Q1M4L9 Cluster: Putative glyoxylate reductase; n=1; Rhi... 36 0.82
UniRef50_A0NJK9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 36 0.82
UniRef50_P53839 Cluster: Putative 2-hydroxyacid dehydrogenase YN... 36 0.82
UniRef50_Q47XK1 Cluster: Erythronate-4-phosphate dehydrogenase; ... 36 0.82
UniRef50_Q6F943 Cluster: Erythronate-4-phosphate dehydrogenase; ... 36 0.82
UniRef50_Q8RG31 Cluster: 2-hydroxyglutarate dehydrogenase; n=4; ... 36 1.1
UniRef50_Q88TW9 Cluster: Phosphoglycerate dehydrogenase; n=1; La... 36 1.1
>UniRef50_UPI0000DB72A4 Cluster: PREDICTED: similar to
3-phosphoglycerate dehydrogenase; n=1; Apis
mellifera|Rep: PREDICTED: similar to 3-phosphoglycerate
dehydrogenase - Apis mellifera
Length = 478
Score = 127 bits (307), Expect = 2e-28
Identities = 57/101 (56%), Positives = 77/101 (76%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID+++A +KGV V+N PG N++SACELTC L+ LAR+V A +LK GRWDR LY+G
Sbjct: 80 DNIDLEAATRKGVIVLNTPGGNSISACELTCALISNLARNVTQAVQSLKDGRWDRKLYSG 139
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSAD 600
EL+GKTLA+L + GREV RM A+GM +I FDP ++++
Sbjct: 140 FELSGKTLAVLGMGRIGREVTRRMQAYGMRVIAFDPLLTSE 180
Score = 67.7 bits (158), Expect = 2e-10
Identities = 33/62 (53%), Positives = 44/62 (70%)
Frame = +2
Query: 62 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTK 241
M ++SVLI D V A C ELL +GI TTK K+SKE+L+ E+ NH+ L+VRS T+VT
Sbjct: 1 MSTTLRSVLISDPVDACCGELLVRHGIPVTTKYKLSKEKLIKELQNHEGLIVRSETKVTA 60
Query: 242 EV 247
+V
Sbjct: 61 DV 62
>UniRef50_UPI00015B605A Cluster: PREDICTED: similar to GA19489-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA19489-PA - Nasonia vitripennis
Length = 511
Score = 126 bits (304), Expect = 4e-28
Identities = 56/104 (53%), Positives = 74/104 (71%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID+ +A + G+ V+N PG N++SACELTC ++ LAR+VV A ++K GRWDR LY G
Sbjct: 80 DNIDIPAATRNGILVLNTPGGNSVSACELTCAVISALARNVVQAGQSMKEGRWDRKLYAG 139
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCA 609
EL+GK L ++ GREVA RM AFGM II +DPF + +Q A
Sbjct: 140 RELSGKALGVVGFGRIGREVAHRMKAFGMEIIAYDPFFTKEQAA 183
Score = 71.7 bits (168), Expect = 1e-11
Identities = 32/63 (50%), Positives = 47/63 (74%)
Frame = +2
Query: 62 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTK 241
M V+++SVL+ D V +CA LL ++G+ TTK K+SKEEL+ E+ HD L+VRS T+VT
Sbjct: 1 MSVNLRSVLVSDPVDERCAALLTSHGVPVTTKYKLSKEELINELQKHDGLIVRSETKVTA 60
Query: 242 EVL 250
+V+
Sbjct: 61 DVI 63
>UniRef50_O43175 Cluster: D-3-phosphoglycerate dehydrogenase; n=53;
Bilateria|Rep: D-3-phosphoglycerate dehydrogenase - Homo
sapiens (Human)
Length = 533
Score = 120 bits (288), Expect = 4e-26
Identities = 53/105 (50%), Positives = 76/105 (72%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+D+++A +KG+ V+N P N+LSA ELTC +++ LAR + A+ ++K G+W+R + G
Sbjct: 81 DNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMG 140
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCAS 612
+EL GKTL IL L GREVATRM +FGM IG+DP +S + AS
Sbjct: 141 TELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSAS 185
Score = 52.0 bits (119), Expect = 1e-05
Identities = 24/63 (38%), Positives = 41/63 (65%)
Frame = +2
Query: 71 DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 250
+++ VLI D + C ++L G+ K +SKEEL+ E+ + + L+VRSAT+VT +V+
Sbjct: 5 NLRKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVI 64
Query: 251 DEA 259
+ A
Sbjct: 65 NAA 67
>UniRef50_A7SFV8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 487
Score = 113 bits (273), Expect = 3e-24
Identities = 55/106 (51%), Positives = 69/106 (65%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID +A GV V+N PG N LSA E TC L+ LARH+ AS + K G+W+R + G
Sbjct: 81 DNIDTVAASLHGVLVMNTPGGNTLSAAEHTCALISSLARHIPQASASTKEGKWERKQFMG 140
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCASS 615
+EL GKTLAI+ L GREVA RM ++G+ IG+DP VS A S
Sbjct: 141 NELFGKTLAIIGLGRIGREVALRMQSYGVKTIGYDPLVSPQDAAES 186
Score = 61.3 bits (142), Expect = 2e-08
Identities = 27/61 (44%), Positives = 42/61 (68%)
Frame = +2
Query: 68 VDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEV 247
+++K VLI D V + C +L G+ K+SKEEL+ EIP +D L+VRSAT+V+++V
Sbjct: 4 LELKRVLISDSVDSCCKTILERNGVTVDVNTKLSKEELVSEIPKYDGLIVRSATKVSEDV 63
Query: 248 L 250
+
Sbjct: 64 I 64
>UniRef50_Q3AQU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Chlorobium/Pelodictyon group|Rep: D-3-phosphoglycerate
dehydrogenase - Chlorobium chlorochromatii (strain CaD3)
Length = 538
Score = 112 bits (270), Expect = 6e-24
Identities = 50/104 (48%), Positives = 71/104 (68%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID+++A ++G+ V++ PG NA+SA E TC ++L ARH+ A LK G W++ LY G
Sbjct: 87 DNIDLEAATRQGIVVMSTPGGNAVSAAEHTCAMLLAAARHIPQAMADLKQGNWNKHLYAG 146
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCA 609
EL GKTL+++ L GREVA RM AFGM I +DP ++ + A
Sbjct: 147 IELEGKTLSLIGLGRVGREVAMRMQAFGMRTIAYDPAIADEDAA 190
Score = 48.0 bits (109), Expect = 2e-04
Identities = 25/63 (39%), Positives = 37/63 (58%)
Frame = +2
Query: 71 DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 250
++ VLI D V +C LL +G T K +S +EL I +++ L+VRSAT + EVL
Sbjct: 11 NVMKVLITDSVHPQCGRLLLQHGFEVTEKPSLSPKELHAIIADYNILIVRSATSLPAEVL 70
Query: 251 DEA 259
+A
Sbjct: 71 AKA 73
>UniRef50_Q58424 Cluster: D-3-phosphoglycerate dehydrogenase; n=7;
Euryarchaeota|Rep: D-3-phosphoglycerate dehydrogenase -
Methanococcus jannaschii
Length = 524
Score = 111 bits (267), Expect = 1e-23
Identities = 51/105 (48%), Positives = 72/105 (68%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNIDV++A +KG+ V+NAP A+++S ELT LML AR++ A+ +LK G WDR + G
Sbjct: 75 DNIDVEAATEKGIIVVNAPDASSISVAELTMGLMLAAARNIPQATASLKRGEWDRKRFKG 134
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCAS 612
EL GKTL ++ L G++V R AFGMNIIG+DP++ + S
Sbjct: 135 IELYGKTLGVIGLGRIGQQVVKRAKAFGMNIIGYDPYIPKEVAES 179
Score = 40.7 bits (91), Expect = 0.029
Identities = 21/59 (35%), Positives = 36/59 (61%)
Frame = +2
Query: 83 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDEA 259
+L+ D + ++L G ++KEELL +I + D LVVRS T+VT++V+++A
Sbjct: 4 ILVTDPLHEDAIKILEEVGEVEVATG-LTKEELLEKIKDADVLVVRSGTKVTRDVIEKA 61
>UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=15;
Actinobacteria (class)|Rep: D-3-phosphoglycerate
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 536
Score = 110 bits (265), Expect = 2e-23
Identities = 54/104 (51%), Positives = 69/104 (66%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+DV +A + GV V+NAP +N +SA EL LML ARH+ PA ALK G W RA YTG
Sbjct: 85 DNVDVRAATQAGVMVVNAPTSNIVSAAELAVALMLAAARHISPAHAALKNGEWKRARYTG 144
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCA 609
+EL KT+ I+ L G VA R+ AFGM I+ +DP+V A + A
Sbjct: 145 TELYEKTVGIVGLGRIGVLVAQRLSAFGMKIVAYDPYVQAGRAA 188
>UniRef50_Q3ZX05 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Dehalococcoides|Rep: D-3-phosphoglycerate dehydrogenase
- Dehalococcoides sp. (strain CBDB1)
Length = 526
Score = 105 bits (253), Expect = 7e-22
Identities = 49/102 (48%), Positives = 68/102 (66%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID+ +A G+ V+NAP N +SA E T LML +ARH+ A+ +LK+G+W R + G
Sbjct: 75 DNIDLKTATGNGIIVVNAPTGNTISATEHTLALMLAMARHIPRANASLKSGQWKRNEFVG 134
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQ 603
SEL GKTL I+ L G E+A R A M +IG+DPF+S ++
Sbjct: 135 SELKGKTLGIVGLGNIGSEIAKRALALEMRVIGYDPFISMER 176
Score = 35.9 bits (79), Expect = 0.82
Identities = 21/60 (35%), Positives = 32/60 (53%)
Frame = +2
Query: 74 IKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 253
+K VL+ D + A L K + EEL+ I +DAL+VRS TQVT ++++
Sbjct: 1 MKKVLVSDALSATGLAPLKEIA-QVDVKTGLKPEELISIIGEYDALLVRSQTQVTADIIN 59
>UniRef50_Q7UQL2 Cluster: Phosphoglycerate dehydrogenase; n=2;
Planctomycetaceae|Rep: Phosphoglycerate dehydrogenase -
Rhodopirellula baltica
Length = 540
Score = 104 bits (250), Expect = 2e-21
Identities = 45/105 (42%), Positives = 71/105 (67%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID +A ++G+ V+N P N +S E T ++L ++R++ A+ +L GRWDR + G
Sbjct: 77 DNIDKPAATRRGIVVMNTPAGNTVSTAEHTFAMLLAMSRNIAAANQSLVEGRWDRKKFMG 136
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCAS 612
+++AGKTL I+ + GREVA+R AF M+++ FDPF++ DQ S
Sbjct: 137 TQVAGKTLGIVGMGRIGREVASRAQAFDMDVVAFDPFLTDDQAES 181
>UniRef50_Q9X1C1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Thermotogaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Thermotoga maritima
Length = 306
Score = 103 bits (248), Expect = 3e-21
Identities = 48/96 (50%), Positives = 62/96 (64%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNIDV A +KG+ V+N PGA+A S EL LML ARH+ A+ +LK G+W++ G
Sbjct: 78 DNIDVQKAKEKGIKVLNTPGASAPSVAELAMGLMLACARHIARATVSLKEGKWEKKALKG 137
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDP 585
EL GKTL ++ G+EVA R AFGM II +DP
Sbjct: 138 KELLGKTLGLIGFGNIGQEVAKRALAFGMKIIAYDP 173
Score = 37.5 bits (83), Expect = 0.27
Identities = 20/57 (35%), Positives = 32/57 (56%)
Frame = +2
Query: 83 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 253
V + D + + +LL T + K+EL+ IP D LVVRSAT+VT ++++
Sbjct: 6 VHVNDPLDKEATQLLMNKEELEVTSEHLEKDELMKIIPEVDVLVVRSATKVTADIIE 62
>UniRef50_A2U4T1 Cluster: D-3-phosphoglycerate dehydrogenase; n=14;
Bacillales|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus coagulans 36D1
Length = 541
Score = 103 bits (247), Expect = 4e-21
Identities = 47/104 (45%), Positives = 70/104 (67%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNIDVD+A +KG+ V+N+PG N +SA E T +ML L+R++ A + AG+W+R + G
Sbjct: 77 DNIDVDAATRKGIIVVNSPGGNTISATEHTLAMMLSLSRNIPQAHKSAAAGKWEREKFKG 136
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCA 609
EL KTL I+ G EVA R AFGM ++G+DP+++ ++ A
Sbjct: 137 VELFKKTLGIIGTGKIGTEVAKRAKAFGMAVLGYDPYLTEERAA 180
>UniRef50_Q0W4A2 Cluster: D-3-phosphoglycerate dehydrogenase; n=11;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Uncultured methanogenic archaeon RC-I
Length = 526
Score = 103 bits (246), Expect = 5e-21
Identities = 45/110 (40%), Positives = 74/110 (67%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+DV +A +KG+ V NAP N ++ACE T ++ML ++R++ A+ +LK+G+W+R+ + G
Sbjct: 76 DNVDVPAATEKGIIVANAPEGNTIAACEHTLSMMLAMSRNIPQANASLKSGKWERSKFMG 135
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCASSIAPR 627
E+ KTL I+ L G E+ R +FGM ++ +DPF +A++ A I R
Sbjct: 136 VEVMNKTLGIIGLGRIGGEITKRARSFGMEVLAYDPFTTAER-AQQIGAR 184
Score = 45.2 bits (102), Expect = 0.001
Identities = 20/57 (35%), Positives = 40/57 (70%), Gaps = 1/57 (1%)
Frame = +2
Query: 83 VLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 250
VL+ D + + ++L + G+ + +++KE+L+ +I +++AL++RS TQVTKEV+
Sbjct: 3 VLVTDPISEEGIKILKSEPGVQVDIETRLTKEQLIEKIKDYNALIIRSETQVTKEVI 59
>UniRef50_Q897N8 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Clostridiales|Rep: D-3-phosphoglycerate dehydrogenase -
Clostridium tetani
Length = 533
Score = 102 bits (245), Expect = 6e-21
Identities = 47/102 (46%), Positives = 65/102 (63%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID+ A K+G+ V N P +N +SACELT L+L +R++ LK G WDR + G
Sbjct: 79 DNIDIPEATKRGIIVANTPDSNTISACELTIGLLLAQSRNIAKTDRFLKEGNWDRDSFMG 138
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQ 603
+EL KTL I+ L G VATRM AF M +I +DP++S ++
Sbjct: 139 TELFNKTLGIIGLGRIGSLVATRMNAFDMKVIAYDPYISDER 180
Score = 39.1 bits (87), Expect = 0.088
Identities = 22/65 (33%), Positives = 36/65 (55%), Gaps = 1/65 (1%)
Frame = +2
Query: 68 VDIKSVLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKE 244
+D +LIVD + K ELL + K + +E+LL I N+D L++RS T + E
Sbjct: 1 MDKAKILIVDKIDTKGIELLESEPNFEVDIKMGLEREKLLNIIENYDGLIIRSDTNIDIE 60
Query: 245 VLDEA 259
+++ A
Sbjct: 61 LMNMA 65
>UniRef50_A7HDB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Anaeromyxobacter sp. Fw109-5
Length = 528
Score = 102 bits (244), Expect = 8e-21
Identities = 41/104 (39%), Positives = 71/104 (68%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+D+ +A ++GV V+N PG ++++ EL +++L L+RHV A+ ++KAG+W++ + G
Sbjct: 77 DNVDLAAATRRGVVVMNTPGGSSITVAELALSMILALSRHVAAATGSVKAGKWEKKRFQG 136
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCA 609
ELAG+TL ++ + G + R A GM ++ FDPF+SA+ A
Sbjct: 137 HELAGRTLGVVGIGNIGSVLVARAVALGMRVVAFDPFISAEAAA 180
>UniRef50_A6C9V4 Cluster: Phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: Phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 541
Score = 101 bits (243), Expect = 1e-20
Identities = 47/104 (45%), Positives = 67/104 (64%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID +A ++G+ V+N P N S E T LM+ LAR++ PA +K G+W+R TG
Sbjct: 77 DNIDRAAATREGIVVMNTPAGNTTSTAEQTIALMMALARNIGPAYATMKEGKWERKKLTG 136
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCA 609
+++AGKTLAI+ L G VA R M +IG+DPF+SA++ A
Sbjct: 137 TQVAGKTLAIIGLGRIGLSVAHRAQGLEMKVIGYDPFMSAERAA 180
>UniRef50_Q1IVI0 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Acidobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Acidobacteria bacterium (strain Ellin345)
Length = 531
Score = 101 bits (242), Expect = 1e-20
Identities = 46/99 (46%), Positives = 67/99 (67%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNI++++A +KG+ V+N PGANA++ E T LML LAR + A+ + AG+W++ G
Sbjct: 77 DNIELEAATRKGIAVMNTPGANAIAVAEHTIGLMLALARFIPRATETMHAGKWEKKSLQG 136
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVS 594
+EL GKTL I+ L G EVA R +FGM ++ DP+VS
Sbjct: 137 TELRGKTLGIVGLGRIGLEVARRAASFGMTLVAHDPYVS 175
>UniRef50_A6UQN3 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Methanococcus|Rep: D-3-phosphoglycerate dehydrogenase -
Methanococcus vannielii SB
Length = 523
Score = 101 bits (241), Expect = 2e-20
Identities = 46/98 (46%), Positives = 67/98 (68%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+D+D+A +KGV V+NAP A+++S EL LML AR++ A+ +LK G WDR + G
Sbjct: 75 DNVDLDAATEKGVVVVNAPDASSISVAELMFGLMLSAARNIPQATASLKKGEWDRKSFKG 134
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFV 591
E+ KTL I+ L G++VA R AF MNI+ +DP++
Sbjct: 135 MEVYAKTLGIVGLGRIGQQVAKRAQAFEMNIVAYDPYI 172
Score = 41.1 bits (92), Expect = 0.022
Identities = 24/57 (42%), Positives = 32/57 (56%)
Frame = +2
Query: 83 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 253
+LI D + E+L G IS EE+ +I + DALVVRS T VTKE++D
Sbjct: 4 ILITDPLHESAIEILKEAGEVEIATG-ISIEEIKQKIKDADALVVRSGTTVTKEIID 59
>UniRef50_P35136 Cluster: D-3-phosphoglycerate dehydrogenase; n=8;
Bacillaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus subtilis
Length = 525
Score = 101 bits (241), Expect = 2e-20
Identities = 48/102 (47%), Positives = 65/102 (63%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID+D A K GV VINAP N +S E T ++ L RH+ A+ ++K+ W+R Y G
Sbjct: 74 DNIDIDEATKHGVIVINAPNGNTISTAEHTFAMISSLMRHIPQANISVKSREWNRTAYVG 133
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQ 603
SEL GKTL I+ L G E+A R AFGM + FDPF++ ++
Sbjct: 134 SELYGKTLGIVGLGRIGSEIAQRRGAFGMTVHVFDPFLTEER 175
>UniRef50_Q2AHU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Halothermothrix orenii H 168|Rep: D-3-phosphoglycerate
dehydrogenase - Halothermothrix orenii H 168
Length = 527
Score = 100 bits (239), Expect = 3e-20
Identities = 48/109 (44%), Positives = 65/109 (59%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID++ A K+G+ V N P N +SA E T +ML L+R++ A+ AL G WDR Y G
Sbjct: 75 DNIDIEEASKRGIIVFNTPTGNTISAVEHTIGMMLALSRNIPQANQALHEGIWDRKKYMG 134
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCASSIAP 624
E+ GKTL I+ L G VA R AFGM +I DP++ ++ A P
Sbjct: 135 VEVKGKTLGIIGLGRIGSRVAVRAQAFGMKVIANDPYLPPEKAAKINVP 183
Score = 41.9 bits (94), Expect = 0.012
Identities = 24/59 (40%), Positives = 33/59 (55%)
Frame = +2
Query: 83 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDEA 259
VL+ D + K E+L T +S+EE L I +D L+VRS T+V KE LD+A
Sbjct: 4 VLVSDNISPKGIEILEQEA-DVTFNPDLSREEFLDIIGEYDGLIVRSMTEVDKEALDKA 61
>UniRef50_A0L7J1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Magnetococcus sp. (strain MC-1)
Length = 527
Score = 100 bits (239), Expect = 3e-20
Identities = 42/105 (40%), Positives = 67/105 (63%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+D +A +KG+ V+N P NA++ EL TL + ARH+ A+ + KAG+W+++ + G
Sbjct: 76 DNVDTPAASQKGIIVMNTPFGNAITTAELGVTLAMAAARHIPAATASTKAGKWEKSRFMG 135
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCAS 612
ELAGKT ++ L GR VA R+ M ++ +DPF++ D+ S
Sbjct: 136 RELAGKTAGVIGLGNVGRLVAQRLAGLDMKVVAYDPFINKDRAIS 180
Score = 37.9 bits (84), Expect = 0.20
Identities = 19/59 (32%), Positives = 31/59 (52%)
Frame = +2
Query: 83 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDEA 259
VLI D + E+ A G+ K +S +ELL I +D + +RSAT++ + + A
Sbjct: 4 VLIADKMSPMAEEVFRARGLEVDVKVGMSPDELLACIDQYDGIAIRSATRLPAQAIAAA 62
>UniRef50_UPI0000E4762C Cluster: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase - Strongylocentrotus
purpuratus
Length = 493
Score = 99 bits (238), Expect = 4e-20
Identities = 50/100 (50%), Positives = 61/100 (61%)
Frame = +1
Query: 304 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSE 483
IDV + G PG N LSA E TC ++ L+R + A LKAG+WDR + GSE
Sbjct: 46 IDVYDYLRMAWGSTYTPGGNTLSAAEHTCAMVCCLSRSLPQAHATLKAGKWDRKAFMGSE 105
Query: 484 LAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQ 603
L GKTL I+ L GREVA RM +FGM IGFDP V A++
Sbjct: 106 LYGKTLGIVGLGRIGREVAQRMQSFGMTTIGFDPIVPAEE 145
Score = 48.4 bits (110), Expect = 1e-04
Identities = 23/45 (51%), Positives = 27/45 (60%)
Frame = +2
Query: 62 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIP 196
M +K VLI D V +CAE+L GI K+SKEELL EIP
Sbjct: 1 MAFSLKKVLISDSVSPRCAEILRENGIEVDNNTKLSKEELLAEIP 45
>UniRef50_Q67TJ9 Cluster: Phosphoglycerate dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: Phosphoglycerate
dehydrogenase - Symbiobacterium thermophilum
Length = 540
Score = 99.1 bits (236), Expect = 8e-20
Identities = 48/99 (48%), Positives = 65/99 (65%), Gaps = 1/99 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL-KAGRWDRALYT 474
DNIDV +A ++GV V+N PGAN S E L++ +AR++ A AL + GRWDR +
Sbjct: 73 DNIDVAAATERGVVVVNVPGANTYSTAEHAFGLLIAVARNIPQAHHALAREGRWDRMSFV 132
Query: 475 GSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFV 591
G+EL GKTL I+ L G EVA R AFGM ++ +DP+V
Sbjct: 133 GTELHGKTLGIIGLGRIGSEVAVRARAFGMRVLAYDPYV 171
Score = 39.1 bits (87), Expect = 0.088
Identities = 18/30 (60%), Positives = 23/30 (76%)
Frame = +2
Query: 161 KISKEELLMEIPNHDALVVRSATQVTKEVL 250
K++ EELL IP +DAL+ RS T+VT EVL
Sbjct: 27 KVTSEELLEIIPEYDALITRSETKVTAEVL 56
>UniRef50_Q8PW48 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Methanomicrobia|Rep: D-3-phosphoglycerate dehydrogenase
- Methanosarcina mazei (Methanosarcina frisia)
Length = 540
Score = 99.1 bits (236), Expect = 8e-20
Identities = 45/99 (45%), Positives = 65/99 (65%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+DVD+A KKG+ V NAP N +SA E T +M+ ++R++ A+ +LKA W R + G
Sbjct: 91 DNVDVDAATKKGIIVANAPEGNMISAAEHTIAMMMSMSRNIPQANASLKAREWKRNKFMG 150
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVS 594
E+ GKTL ++ L G EVA R MN++G+DPF+S
Sbjct: 151 VEVKGKTLGVIGLGRIGSEVAKRAAGLEMNLMGYDPFIS 189
Score = 38.3 bits (85), Expect = 0.15
Identities = 21/64 (32%), Positives = 39/64 (60%)
Frame = +2
Query: 68 VDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEV 247
+D+K VL+ D + + E+L + + ++EL+ +I +DALV+RS TQVT+ +
Sbjct: 16 IDMK-VLVSDSLSNEGLEILKEH-FDIDVCTGLCEDELVEKIKGYDALVIRSGTQVTQRI 73
Query: 248 LDEA 259
++ A
Sbjct: 74 IEAA 77
>UniRef50_O29445 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Archaeoglobus fulgidus
Length = 527
Score = 99.1 bits (236), Expect = 8e-20
Identities = 44/102 (43%), Positives = 65/102 (63%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID+++A ++G+ V+NAPG N +S E LML AR + A ++K G+W+R + G
Sbjct: 75 DNIDINAATQRGIVVVNAPGGNTISTAEHAIALMLAAARKIPQADRSVKEGKWERKKFMG 134
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQ 603
EL GKT ++ L G EVA R A MN++ +DPFVS ++
Sbjct: 135 IELRGKTAGVIGLGRVGFEVAKRCKALEMNVLAYDPFVSKER 176
Score = 47.2 bits (107), Expect = 3e-04
Identities = 20/59 (33%), Positives = 36/59 (61%)
Frame = +2
Query: 83 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDEA 259
VL+ + + + + + G+ K +S+EEL+ E+P ++A+VVRS T+V EV+ A
Sbjct: 3 VLVAEPISEEAIDYMRKNGLEVEVKTGMSREELIREVPKYEAIVVRSQTKVDAEVIQAA 61
>UniRef50_Q1PZY1 Cluster: Similar to D-3-phosphoglycerate
dehydrogenase; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similar to D-3-phosphoglycerate
dehydrogenase - Candidatus Kuenenia stuttgartiensis
Length = 535
Score = 98.7 bits (235), Expect = 1e-19
Identities = 44/101 (43%), Positives = 64/101 (63%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNIDV +A KKG+ V+N P N +S E T L+ L+R V A ++K G+W++ +TG
Sbjct: 84 DNIDVPAATKKGIVVMNTPAGNIISTAEHTIALLCSLSRFVPQACASVKEGKWEKKKFTG 143
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSAD 600
+L GKT I+ L GR+VA R A M +IG+DPF++ +
Sbjct: 144 QQLTGKTFGIIGLGRVGRQVAKRAAALEMKVIGYDPFITTE 184
Score = 35.5 bits (78), Expect = 1.1
Identities = 20/59 (33%), Positives = 31/59 (52%)
Frame = +2
Query: 83 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDEA 259
VLI D + C E+L G+ K + EL I D ++VRS T++T VL+++
Sbjct: 12 VLIADDLPDVCNEILQNAGVEVLKKTGLKPPELDAVIKMCDGVIVRSNTKLTAPVLEKS 70
>UniRef50_A5UQ03 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Chloroflexi (class)|Rep: D-3-phosphoglycerate
dehydrogenase - Roseiflexus sp. RS-1
Length = 524
Score = 97.1 bits (231), Expect = 3e-19
Identities = 42/104 (40%), Positives = 70/104 (67%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID+++A ++G+ V+NAP +N+++ ELT L+L LARH+ A +++ AG+W+R + G
Sbjct: 75 DNIDLEAATRQGIMVVNAPASNSVAVAELTIALILSLARHIPQAHSSVVAGKWERNRFMG 134
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCA 609
E+ KTL ++ L G EVA R M+++ +DP VS ++ A
Sbjct: 135 FEVRNKTLGLVGLGRIGAEVARRARGLEMHVVAYDPVVSTERAA 178
Score = 35.9 bits (79), Expect = 0.82
Identities = 16/32 (50%), Positives = 23/32 (71%)
Frame = +2
Query: 155 KAKISKEELLMEIPNHDALVVRSATQVTKEVL 250
+ + K L+ +P +DAL+VRSAT+VT EVL
Sbjct: 27 RTDLDKAGLIAILPEYDALIVRSATRVTAEVL 58
>UniRef50_A0LMX1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep:
D-3-phosphoglycerate dehydrogenase - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 525
Score = 96.3 bits (229), Expect = 5e-19
Identities = 45/111 (40%), Positives = 69/111 (62%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNIDV +A +G V+N PGANA +A E T +ML LARH+ A+ +++ GRWD+ + G
Sbjct: 76 DNIDVKAASARGALVMNTPGANATAAAEHTIAMMLALARHIPQATQSMREGRWDKKRFMG 135
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCASSIAPRW 630
+EL +TL I+ L G VA R + M+++G DP++ + A+ + W
Sbjct: 136 TELFHQTLGIIGLGKIGSIVADRALSMKMDVLGHDPYI-IPEAAAILGVEW 185
Score = 38.3 bits (85), Expect = 0.15
Identities = 21/60 (35%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Frame = +2
Query: 83 VLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDEA 259
VLI DG+ +L A GI + EE+ +P++DA++VRS T++T E+++ A
Sbjct: 3 VLICDGMHEVGLSILRAAEGIDVDVPDQPGAEEIKAMLPDYDAVIVRSRTRITAELIENA 62
>UniRef50_O04130 Cluster: D-3-phosphoglycerate dehydrogenase,
chloroplast precursor; n=13; Magnoliophyta|Rep:
D-3-phosphoglycerate dehydrogenase, chloroplast
precursor - Arabidopsis thaliana (Mouse-ear cress)
Length = 624
Score = 95.1 bits (226), Expect = 1e-18
Identities = 43/102 (42%), Positives = 63/102 (61%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+D+ +A + G V+NAP AN ++A E L+ +AR+V A ++KAG+W+R+ Y G
Sbjct: 157 DNVDLQAATEHGCLVVNAPTANTVAAAEHGIALLASMARNVAQADASIKAGKWERSKYVG 216
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQ 603
L GKTLA++ G EVA R GM +I DP+ AD+
Sbjct: 217 VSLVGKTLAVMGFGKVGTEVARRAKGLGMTVISHDPYAPADR 258
Score = 38.7 bits (86), Expect = 0.12
Identities = 20/59 (33%), Positives = 34/59 (57%)
Frame = +2
Query: 83 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDEA 259
+L+ + +G LL +G + +S E+L ++ DAL+VRS T+VT+EV + A
Sbjct: 85 ILVTEKLGEAGVNLLREFGDVDCSY-DLSPEDLKKKVAESDALIVRSGTKVTREVFEAA 142
>UniRef50_Q8TYK0 Cluster: Predicted dehydrogenase related to
phosphoglycerate dehydrogenase; n=9; Archaea|Rep:
Predicted dehydrogenase related to phosphoglycerate
dehydrogenase - Methanopyrus kandleri
Length = 522
Score = 93.9 bits (223), Expect = 3e-18
Identities = 42/98 (42%), Positives = 65/98 (66%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNIDV +A ++G+ V+NAP ++++S E T L+L LAR + A +++ G WDR + G
Sbjct: 75 DNIDVKAATERGIIVVNAPESSSISVAEHTMGLILALARKIPQADRSVRRGEWDRKRFMG 134
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFV 591
ELAGKTL ++ L G++VA R AF M + +DP++
Sbjct: 135 VELAGKTLGLIGLGRIGQQVAKRAKAFEMEVTAYDPYI 172
Score = 33.1 bits (72), Expect = 5.8
Identities = 18/59 (30%), Positives = 31/59 (52%)
Frame = +2
Query: 83 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDEA 259
+L+ D + L G + +EE+ + + DA VVRS T+VT+E+++EA
Sbjct: 4 ILVTDPIHEDALRKLEELGEVVVLE-DADEEEIREHVRDADAWVVRSGTRVTRELIEEA 61
>UniRef50_Q1AXS3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep:
D-3-phosphoglycerate dehydrogenase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 527
Score = 93.1 bits (221), Expect = 5e-18
Identities = 43/105 (40%), Positives = 66/105 (62%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID+++A K+G+ V NAP +N ++A E T LML +AR + A +L+ G W+RA + G
Sbjct: 74 DNIDIEAATKRGILVANAPESNTVAAAEHTLGLMLAVARRIPAADASLRRGEWNRAAFKG 133
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCAS 612
E+A KTL ++ L G VA GM ++ +DP+VS ++ S
Sbjct: 134 VEVAEKTLGLVGLGHVGSIVARGALGMGMRVLAYDPYVSEERMRS 178
Score = 36.3 bits (80), Expect = 0.62
Identities = 22/59 (37%), Positives = 32/59 (54%)
Frame = +2
Query: 83 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDEA 259
VL+ + + + ELL +S ELL I +D L+VRSAT+VT EV++ A
Sbjct: 3 VLVTEKLAERGVELLRRE-FEVDVLLGLSPGELLERIGEYDGLIVRSATKVTAEVIEAA 60
>UniRef50_A7CYD6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Opitutaceae bacterium TAV2|Rep: D-3-phosphoglycerate
dehydrogenase - Opitutaceae bacterium TAV2
Length = 529
Score = 92.7 bits (220), Expect = 7e-18
Identities = 40/99 (40%), Positives = 66/99 (66%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+DV++A ++GV V+N P N ++ ELT T +L +R V A+ +++ G+WDR ++G
Sbjct: 76 DNVDVEAATERGVVVMNTPAGNTIATAELTFTHILCGSRPVSQAAASMREGKWDRKSFSG 135
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVS 594
EL KTL ++ + G EVA R AFGM ++ +DP+++
Sbjct: 136 VELFKKTLGVIGMGRIGGEVARRAVAFGMKVLAYDPYLA 174
>UniRef50_A6C2G1 Cluster: Phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: Phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 316
Score = 92.7 bits (220), Expect = 7e-18
Identities = 46/101 (45%), Positives = 60/101 (59%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+D + A +KG+ V P AN+LS ELT LML L R + A G W+R +TG
Sbjct: 77 DNVDTEYAHEKGIVVCFTPDANSLSVAELTIGLMLALMRKIPEARQDTLTGGWNRLKFTG 136
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSAD 600
+EL GK+ ++ L G ATR AFGMNI+ DPF+ AD
Sbjct: 137 TELYGKSFGLIGLGRIGSFTATRAKAFGMNILAADPFLKAD 177
>UniRef50_A4FIF2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 316
Score = 92.7 bits (220), Expect = 7e-18
Identities = 45/98 (45%), Positives = 65/98 (66%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID+D+A +G+ V+ APG+N+ + ELT LM+ AR + A TA+ AG W + LY G
Sbjct: 82 DNIDLDAARARGIPVVFAPGSNSRAVAELTFGLMIAAARRIAAAHTAVVAGDWPK-LY-G 139
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFV 591
ELAG+TL ++ GR +A AFGM ++G+DPF+
Sbjct: 140 PELAGRTLGVIGFGRIGRLLAGYAQAFGMTVVGYDPFL 177
>UniRef50_O33116 Cluster: D-3-phosphoglycerate dehydrogenase; n=28;
Actinomycetales|Rep: D-3-phosphoglycerate dehydrogenase
- Mycobacterium leprae
Length = 528
Score = 92.7 bits (220), Expect = 7e-18
Identities = 42/104 (40%), Positives = 68/104 (65%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+DVD+A +GV V+NAP +N SA E L+L +R + A +L+A W R+ ++G
Sbjct: 77 DNVDVDAATARGVLVVNAPTSNIHSAAEHALALLLAASRQIAEADASLRAHIWKRSSFSG 136
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCA 609
+E+ GKT+ ++ L G+ VA R+ AFG ++I +DP+V+ + A
Sbjct: 137 TEIFGKTVGVVGLGRIGQLVAARIAAFGAHVIAYDPYVAPARAA 180
>UniRef50_UPI0000DC0E13 Cluster: 3-phosphoglycerate dehydrogenase;
n=4; Amniota|Rep: 3-phosphoglycerate dehydrogenase -
Rattus norvegicus
Length = 316
Score = 91.9 bits (218), Expect = 1e-17
Identities = 46/105 (43%), Positives = 65/105 (61%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+++++A K + V+N P +LSA ELTC +++ L R + P G+WD+ + G
Sbjct: 75 DNVNLEAAMTKSILVMNTPNGKSLSASELTCGMIVCLTRQIPP-------GKWDQEEFMG 127
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCAS 612
+EL GKTL IL L GREV T+M AF M +GFDP S + AS
Sbjct: 128 TELNGKTLGILGLGRIGREVTTQMQAFRMKAVGFDPISSPEIAAS 172
Score = 33.5 bits (73), Expect = 4.4
Identities = 20/60 (33%), Positives = 31/60 (51%)
Frame = +2
Query: 71 DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 250
++ VLI D + C +LL G+ K +SKEEL++EI + + V + T E L
Sbjct: 5 NLHKVLISDILDPGCWKLLKDGGLQVVEKQNLSKEELIVEIQDCETTKVTADVTNTAEKL 64
>UniRef50_Q2LGV1 Cluster: Phosphoglycerate dehydrogenase; n=6;
Halobacteriaceae|Rep: Phosphoglycerate dehydrogenase -
Haloquadratum walsbyi
Length = 536
Score = 91.9 bits (218), Expect = 1e-17
Identities = 41/102 (40%), Positives = 64/102 (62%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID+D+A + GV V NAP N +A E T + AR + A L+ G W ++ Y G
Sbjct: 79 DNIDIDAATEHGVIVANAPEGNVRAAAEHTVAMTFAGARSIPQAHARLRTGEWAKSEYLG 138
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQ 603
+E+ GKTL ++ L G+EVA R+ + GM+++ +DP++S D+
Sbjct: 139 TEVNGKTLGVVGLGRVGQEVAKRLESLGMDLVAYDPYISEDR 180
Score = 36.3 bits (80), Expect = 0.62
Identities = 23/59 (38%), Positives = 30/59 (50%)
Frame = +2
Query: 83 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDEA 259
VL+ D + E L A G + T I E LL I + +ALVVRS T V + V + A
Sbjct: 7 VLVTDPIDDAGLERLRAAGHSVETAYDIGDEALLNTITDVNALVVRSGTDVNEAVFEAA 65
>UniRef50_O67741 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Aquifex aeolicus|Rep: D-3-phosphoglycerate dehydrogenase
- Aquifex aeolicus
Length = 533
Score = 91.1 bits (216), Expect = 2e-17
Identities = 40/102 (39%), Positives = 63/102 (61%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+D++ A K+G+ V+N PGAN + A ELT ML + R+ A ++ +WDR + G
Sbjct: 77 DNVDIEEATKRGILVVNTPGANTIGATELTMMHMLTIMRNGHKAHESMLNYKWDRKKFMG 136
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQ 603
EL G+ L I+ L G +VA R AFGM ++ +DP++ ++
Sbjct: 137 EELYGRILGIIGLGNIGSQVAIRAKAFGMKVMAYDPYIPREK 178
Score = 39.9 bits (89), Expect = 0.050
Identities = 25/60 (41%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
Frame = +2
Query: 83 VLIVDGVGAKCAELLNAYG-IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDEA 259
VLI D + + ELL + + IS EELL I + DA++ RS T VTKE+L+ A
Sbjct: 4 VLITDPIAPEGIELLQKDPEVEVYNEPDISYEELLEIIKDFDAIITRSRTPVTKELLERA 63
>UniRef50_A7P9P5 Cluster: Chromosome chr3 scaffold_8, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr3 scaffold_8, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 653
Score = 91.1 bits (216), Expect = 2e-17
Identities = 41/102 (40%), Positives = 62/102 (60%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+D+ +A + G V+NAP AN ++A E L+ +AR+V A ++K+G+W R Y G
Sbjct: 186 DNVDLAAATEHGCLVVNAPTANTVAAAEHGIALLTAMARNVAQADASVKSGKWQRNKYVG 245
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQ 603
L GKTLA++ G EV R GM++I DP+ +AD+
Sbjct: 246 VSLVGKTLAVMGFGKVGSEVTRRAKGLGMHVIAHDPYAAADR 287
Score = 37.5 bits (83), Expect = 0.27
Identities = 27/68 (39%), Positives = 39/68 (57%)
Frame = +2
Query: 80 SVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDEA 259
+VL+ + +GA +LL + +S EEL +I DAL+VRS T+V++EV EA
Sbjct: 113 TVLVAEKLGAAGLDLLKDFANVDCAY-NLSPEELCTKISLCDALIVRSGTKVSREVF-EA 170
Query: 260 *S*RWSVV 283
S R VV
Sbjct: 171 SSGRLKVV 178
>UniRef50_A1DFM4 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
Fungi/Metazoa group|Rep: D-3-phosphoglycerate
dehydrogenase - Neosartorya fischeri (strain ATCC 1020 /
DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain
ATCC 1020 / DSM 3700 / NRRL 181))
Length = 582
Score = 90.2 bits (214), Expect = 4e-17
Identities = 40/99 (40%), Positives = 63/99 (63%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+DV+ A K G+ V+N+P N +A E T L++ +AR++ A ++LK+G+W+R+ + G
Sbjct: 82 DNVDVEEATKLGIVVVNSPSGNIGAAAEHTIALLIAMARNIPEACSSLKSGKWERSKFVG 141
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVS 594
E+ GKTL+I+ L G VA GMN+ DP+ S
Sbjct: 142 VEVKGKTLSIIGLGKVGLTVARLAKGLGMNVNALDPYAS 180
Score = 33.5 bits (73), Expect = 4.4
Identities = 21/59 (35%), Positives = 32/59 (54%)
Frame = +2
Query: 83 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDEA 259
VL+ + + LL A + + + +ELL IP ++ALVVRS T+VT +L A
Sbjct: 11 VLVPEKLSPDGLALLRA-SLEVDERRGLDADELLQIIPEYEALVVRSETKVTGNLLRAA 68
>UniRef50_Q8UJZ6 Cluster: Phosphoglycerate dehydrogenase; n=3;
Alphaproteobacteria|Rep: Phosphoglycerate dehydrogenase
- Agrobacterium tumefaciens (strain C58 / ATCC 33970)
Length = 354
Score = 89.8 bits (213), Expect = 5e-17
Identities = 38/97 (39%), Positives = 60/97 (61%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNIDVD+A ++ + V+ A GANALS E TL+ + + +VP + ++AGRW++A Y+G
Sbjct: 105 DNIDVDAASRREIPVVVAAGANALSVAEHAITLLFAVVKRIVPLDSGIRAGRWEKAGYSG 164
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPF 588
ELAG + ++ R+ A FG+ + +DPF
Sbjct: 165 KELAGMIIGLVGFGAIARQTAVFARGFGLKVQAYDPF 201
>UniRef50_Q8EN61 Cluster: Phosphoglycerate dehydrogenase; n=2;
Bacillaceae|Rep: Phosphoglycerate dehydrogenase -
Oceanobacillus iheyensis
Length = 528
Score = 89.8 bits (213), Expect = 5e-17
Identities = 44/102 (43%), Positives = 63/102 (61%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID+++A + GV V+NAP N SA E T +++ L+R++ A ALK +WDR + G
Sbjct: 78 DNIDLEAATENGVIVVNAPNGNTNSAAEHTMAMIMALSRNIPQAYHALKQKQWDRKRFVG 137
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQ 603
EL KTL I+ L G EVA R MN+I +DPF + ++
Sbjct: 138 VELKQKTLGIVGLGRIGAEVAARAKGQRMNVIAYDPFFTEEK 179
>UniRef50_Q4L766 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Staphylococcus|Rep: D-3-phosphoglycerate dehydrogenase -
Staphylococcus haemolyticus (strain JCSC1435)
Length = 532
Score = 89.8 bits (213), Expect = 5e-17
Identities = 40/102 (39%), Positives = 65/102 (63%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID+D+A +G+ VINAP N +SA E + ++L +AR++ A +LK W+R + G
Sbjct: 78 DNIDIDAATLQGILVINAPDGNTISATEHSVAMILAMARNIPQAHASLKNKEWNRKAFKG 137
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQ 603
EL KTL ++ G VA R+ +FGM ++ +DP+++ D+
Sbjct: 138 VELYQKTLGVIGAGRIGIGVAQRLQSFGMKVLAYDPYLTEDK 179
Score = 35.9 bits (79), Expect = 0.82
Identities = 19/61 (31%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
Frame = +2
Query: 80 SVLIVDGVGAKCAE-LLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDE 256
++L+ D + + LLN K + ++ LL I +++ L+VRS TQVT++V+++
Sbjct: 4 NILVSDPISTDGLQSLLNHSDFNVDIKTDLDEQSLLDIIGDYEGLIVRSQTQVTQQVIEK 63
Query: 257 A 259
A
Sbjct: 64 A 64
>UniRef50_P73821 Cluster: D-3-phosphoglycerate dehydrogenase; n=37;
Cyanobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Synechocystis sp. (strain PCC 6803)
Length = 554
Score = 89.8 bits (213), Expect = 5e-17
Identities = 38/102 (37%), Positives = 65/102 (63%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNIDV +A ++G+ V+N+P N ++A E +M+ LARH+ A+ ++K +W+R + G
Sbjct: 103 DNIDVPAATRQGIVVVNSPEGNTIAAAEHALAMMMALARHIPDANKSVKESKWERKQFIG 162
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQ 603
+E+ KTL ++ L G VA A GM ++ +DPF+S ++
Sbjct: 163 TEVYKKTLGVVGLGKIGSHVAGVAKAMGMKLLAYDPFISQER 204
Score = 34.7 bits (76), Expect = 1.9
Identities = 16/56 (28%), Positives = 34/56 (60%)
Frame = +2
Query: 83 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 250
VL+ D + ++L K +S+ E++ +P +DA+++RSAT+VT++++
Sbjct: 32 VLVSDSIDQVGIDILKQVA-QVDVKTGLSEAEIIDIVPEYDAIMLRSATKVTEKII 86
>UniRef50_Q1NQ97 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=2;
Bacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - delta
proteobacterium MLMS-1
Length = 304
Score = 89.4 bits (212), Expect = 6e-17
Identities = 39/102 (38%), Positives = 62/102 (60%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+DV +A KKGV V+NAP NA +A E ++M+ L R++ A+ ++KAG+W++ + G
Sbjct: 75 DNVDVPAASKKGVVVMNAPDGNATTAAEHAVSMMMALTRNIPQATASMKAGKWEKKKFQG 134
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQ 603
E+ K ++ + GR A R M +I FDP + A+Q
Sbjct: 135 HEVTAKVAGVVGIGRIGRIFAERAMGLRMKVIAFDPHMPAEQ 176
Score = 44.8 bits (101), Expect = 0.002
Identities = 22/59 (37%), Positives = 36/59 (61%)
Frame = +2
Query: 83 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDEA 259
VLI D + +++ G+ + +S EEL+ IP +D LV+RSA++VT E+L+ A
Sbjct: 3 VLISDNLAPVGEKIMRDAGLEVDVRTGLSPEELVKIIPAYDGLVIRSASKVTAEILEAA 61
>UniRef50_A3EWA5 Cluster: Phosphoglycerate dehydrogenase; n=2;
Bacteria|Rep: Phosphoglycerate dehydrogenase -
Leptospirillum sp. Group II UBA
Length = 535
Score = 88.2 bits (209), Expect = 1e-16
Identities = 38/106 (35%), Positives = 67/106 (63%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+D+++A ++G+ V+N PG N ++ E T +L++ +AR + A+ + KAG+W+++ + G
Sbjct: 79 DNVDLEAATERGIVVMNTPGGNTVTTAEHTMSLLMSMARRIPQANASNKAGKWEKSKFMG 138
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCASS 615
EL KTL I+ + G+ VA MNII FDP+++ + S
Sbjct: 139 VELFQKTLGIVGMGKIGQHVAQIARGIAMNIIAFDPYLTPEVAEKS 184
Score = 48.0 bits (109), Expect = 2e-04
Identities = 25/66 (37%), Positives = 36/66 (54%)
Frame = +2
Query: 62 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTK 241
M DI+ +LI D + + G K K+S +EL EI +D LV+RS T+VT+
Sbjct: 1 MSSDIR-ILISDAISEDGVRIFQKAGFHVDMKTKLSPQELAQEISQYDGLVIRSGTKVTR 59
Query: 242 EVLDEA 259
E+L A
Sbjct: 60 EILKNA 65
>UniRef50_Q8R716 Cluster: Phosphoglycerate dehydrogenase and related
dehydrogenases; n=5; Clostridia|Rep: Phosphoglycerate
dehydrogenase and related dehydrogenases -
Thermoanaerobacter tengcongensis
Length = 533
Score = 87.4 bits (207), Expect = 3e-16
Identities = 42/98 (42%), Positives = 63/98 (64%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNIDV++A ++G+ V+N P N ++A ELT LML +AR++ A A G + R + G
Sbjct: 74 DNIDVEAATQRGILVVNTPAGNTIAAAELTIGLMLAIARNIPQAYHAALNGDFRRDRFKG 133
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFV 591
EL GKT+ I+ L G VA+R+ AF M +I +DP++
Sbjct: 134 VELNGKTVGIIGLGRIGSLVASRLAAFNMRVIAYDPYM 171
Score = 41.1 bits (92), Expect = 0.022
Identities = 19/58 (32%), Positives = 36/58 (62%)
Frame = +2
Query: 83 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDE 256
+++ + + + L Y K IS+EELL I ++DA++VRSAT+V +E++++
Sbjct: 3 IIVTEKISENGIDYLKKYA-DVDVKTNISREELLEVIKDYDAIIVRSATKVDRELIEK 59
>UniRef50_Q8YIU3 Cluster: D-3-PHOSPHOGLYCERATE DEHYDROGENASE; n=75;
Bacteria|Rep: D-3-PHOSPHOGLYCERATE DEHYDROGENASE -
Brucella melitensis
Length = 538
Score = 86.2 bits (204), Expect = 6e-16
Identities = 36/99 (36%), Positives = 61/99 (61%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+D+ +A ++G+ V+N P N+++ E LM +AR + A T+ +AG+W++ + G
Sbjct: 84 DNVDIPAASRRGIIVMNTPFGNSITTAEHAIALMFAVARQLPEADTSTRAGKWEKNRFMG 143
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVS 594
E+ GKTL ++ G VATR M+++ FDPF+S
Sbjct: 144 VEITGKTLGVVGCGNIGSIVATRGIGLKMHVVAFDPFLS 182
>UniRef50_A6PUG1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Victivallis vadensis
ATCC BAA-548|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Victivallis vadensis ATCC
BAA-548
Length = 524
Score = 85.4 bits (202), Expect = 1e-15
Identities = 36/99 (36%), Positives = 60/99 (60%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
+ ID+ A K + V+N PGAN+ + E +ML +RH++PA + + G W+++ + G
Sbjct: 75 NTIDIKYARKHDIDVMNTPGANSNAVAEEVVAMMLAASRHLIPADISTRKGDWEKSKFMG 134
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVS 594
EL GKT+ IL L G+ + R+ F M ++G+DP +S
Sbjct: 135 RELTGKTVGILGLGHIGQLLVKRLAGFEMKVLGYDPMLS 173
>UniRef50_Q8EMJ8 Cluster: Hypothetical conserved protein; n=1;
Oceanobacillus iheyensis|Rep: Hypothetical conserved
protein - Oceanobacillus iheyensis
Length = 319
Score = 85.0 bits (201), Expect = 1e-15
Identities = 45/103 (43%), Positives = 61/103 (59%), Gaps = 2/103 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 474
DNIDV +A K G+ V N P AN + EL T ML RH++P A++AG +D R
Sbjct: 76 DNIDVKAATKYGIKVTNTPSANINAVAELVLTFMLASTRHLLPIDEAVRAGNFDIRNQLF 135
Query: 475 GSELAGKTLAILALAXXGREVATR-MYAFGMNIIGFDPFVSAD 600
G EL GKT+ I+ GR +A + GMNI+ FDP+V+A+
Sbjct: 136 GYELNGKTVGIIGFGNIGRLIAEKCRLGLGMNIVVFDPYVTAE 178
>UniRef50_Q8ZTC7 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Thermoproteaceae|Rep: D-3-phosphoglycerate dehydrogenase
- Pyrobaculum aerophilum
Length = 307
Score = 83.8 bits (198), Expect = 3e-15
Identities = 40/95 (42%), Positives = 57/95 (60%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+DV+ A KKG+ V++AP A + S ELT L+ +AR + + +KAG W + Y G
Sbjct: 75 DNVDVEYAVKKGIAVVSAPNAPSQSVAELTIGLLFSVARRIPLLNAKVKAGEWPKGKYIG 134
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
E+AGKT+ I+ GR VA + GMNI+ D
Sbjct: 135 IEIAGKTMGIVGFGRIGRFVAQMAKSLGMNILASD 169
Score = 39.1 bits (87), Expect = 0.088
Identities = 20/58 (34%), Positives = 31/58 (53%)
Frame = +2
Query: 80 SVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 253
S LIVD V E L GI ISK++L+ I N++ L+ R ++ K+++D
Sbjct: 2 SALIVDKVDETLKERLERIGIKVDLAPGISKDDLIKIIKNYNILIFRGRLKIDKDIMD 59
>UniRef50_Q0EUV6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Thermoanaerobacter
ethanolicus|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Thermoanaerobacter
ethanolicus X514
Length = 320
Score = 83.4 bits (197), Expect = 4e-15
Identities = 41/97 (42%), Positives = 61/97 (62%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+D+++A KKG+ V N P AN S +L LMLVLAR+++ +K+G W R + G
Sbjct: 84 DNVDLNAAKKKGIVVTNTPNANNNSVADLVIGLMLVLARNLLAVDRIVKSGGWKRIM--G 141
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPF 588
+E+ GKTL I+ L G+ VA R F MN++ +D +
Sbjct: 142 TEIYGKTLGIIGLGKIGKGVAKRAKGFDMNVLCYDVY 178
>UniRef50_A0V9Y4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Comamonadaceae|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Delftia acidovorans SPH-1
Length = 354
Score = 83.4 bits (197), Expect = 4e-15
Identities = 42/95 (44%), Positives = 55/95 (57%)
Frame = +1
Query: 301 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGS 480
NIDV +A ++G+ V PGANA S E+T LM AR + L+AGRW RA G
Sbjct: 107 NIDVAAASQRGIPVYVTPGANAQSVAEMTLGLMFAAARRIAWMDAELRAGRWSRA-QDGL 165
Query: 481 ELAGKTLAILALAXXGREVATRMYAFGMNIIGFDP 585
EL+G+TL +L G+ VA A GM ++ FDP
Sbjct: 166 ELSGRTLGLLGFGQVGQRVARVALALGMQVVAFDP 200
>UniRef50_Q6MN05 Cluster: Phosphoglycerate dehydrogenase; n=1;
Bdellovibrio bacteriovorus|Rep: Phosphoglycerate
dehydrogenase - Bdellovibrio bacteriovorus
Length = 328
Score = 82.6 bits (195), Expect = 7e-15
Identities = 43/113 (38%), Positives = 63/113 (55%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
D+ID+++ K GV V++ P AN SA +LT L+L ++ A +KAG W+R TG
Sbjct: 77 DHIDLEATQKWGVTVMHTPTANIESAAQLTWGLVLSCVNNIQAAHKMVKAGEWNRDQITG 136
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCASSIAPRWSW 636
ELAG+ I+ L G VA AFGMN++ +DP+ + PR S+
Sbjct: 137 IELAGRNYGIVGLGRIGSRVAELAQAFGMNVVAYDPYQEDEVFERLHIPRLSY 189
>UniRef50_Q0J5C2 Cluster: Os08g0447000 protein; n=11;
Viridiplantae|Rep: Os08g0447000 protein - Oryza sativa
subsp. japonica (Rice)
Length = 666
Score = 82.2 bits (194), Expect = 9e-15
Identities = 45/114 (39%), Positives = 62/114 (54%), Gaps = 12/114 (10%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA---------- 447
DN+D+ +A + G V+NAP AN ++A E L+ +AR+V A ALKA
Sbjct: 152 DNVDLQAATEAGCLVVNAPTANTVAAAEHGIALLASMARNVSQADAALKAVYSRTLTVFT 211
Query: 448 --GRWDRALYTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQ 603
G+W R Y G L GKTLA++ G EVA R GM++I DP+ AD+
Sbjct: 212 AQGKWQRTKYVGVSLVGKTLAVMGFGKVGSEVARRAKGLGMHVIAHDPYAPADR 265
Score = 35.9 bits (79), Expect = 0.82
Identities = 16/30 (53%), Positives = 23/30 (76%)
Frame = +2
Query: 164 ISKEELLMEIPNHDALVVRSATQVTKEVLD 253
+S ELL ++ DAL+VRS T+VT+EVL+
Sbjct: 106 MSPAELLAKVAQFDALIVRSGTKVTREVLE 135
>UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Ignicoccus hospitalis
KIN4/I|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Ignicoccus hospitalis
KIN4/I
Length = 308
Score = 81.8 bits (193), Expect = 1e-14
Identities = 41/95 (43%), Positives = 59/95 (62%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID+++A +KG+ V+NAP A + EL +M+VLAR + L G W++ + G
Sbjct: 77 DNIDLEAAKEKGIKVVNAPDALKNAVAELVIGMMVVLARRAHYSYRKLLEGEWEKVM--G 134
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
ELAGKTL ++ GREVA + A GMN+I +D
Sbjct: 135 FELAGKTLGVVGFGRIGREVAKKAKALGMNVIAYD 169
>UniRef50_A1HSQ7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Thermosinus
carboxydivorans Nor1|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Thermosinus
carboxydivorans Nor1
Length = 317
Score = 81.4 bits (192), Expect = 2e-14
Identities = 43/95 (45%), Positives = 55/95 (57%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
+ IDV +A G+ V PGAN +S EL LML +ARH+ ++ G W R TG
Sbjct: 82 NTIDVAAAAAYGIPVTITPGANNISVAELAIGLMLAVARHIPQMDGIVRRGGWSR--MTG 139
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
SEL GK L I+ + G EVA R +AFGM II +D
Sbjct: 140 SELYGKVLGIIGMGSIGCEVAKRAHAFGMKIIAYD 174
>UniRef50_Q9WYG2 Cluster: Phosphoglycerate dehydrogenase, putative;
n=2; Thermotoga|Rep: Phosphoglycerate dehydrogenase,
putative - Thermotoga maritima
Length = 327
Score = 81.0 bits (191), Expect = 2e-14
Identities = 42/102 (41%), Positives = 61/102 (59%), Gaps = 1/102 (0%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL-KAGRWDRALYT 474
DNID+++A KKG+ V GAN+LS ELT + L+R +V A L RW+ +
Sbjct: 74 DNIDLEAATKKGIPVTITAGANSLSVAELTIAFIFALSRGLVWAHNKLFLERRWEGTV-- 131
Query: 475 GSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSAD 600
G E++GKTL ++ GREV + GMN++ +DP+VS D
Sbjct: 132 GQEVSGKTLGVVGFGSIGREVVKKAVCLGMNVLVYDPYVSKD 173
>UniRef50_Q7D366 Cluster: AGR_pAT_578p; n=2; Agrobacterium
tumefaciens str. C58|Rep: AGR_pAT_578p - Agrobacterium
tumefaciens (strain C58 / ATCC 33970)
Length = 317
Score = 80.6 bits (190), Expect = 3e-14
Identities = 40/106 (37%), Positives = 61/106 (57%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID+D+A + G+ V NAPG NA + ELT L+L R + AL+ G WDR + G
Sbjct: 83 DNIDIDAAHRHGIAVTNAPGGNANAVAELTLGLILSAMRRIPYLHDALRGGAWDR--FVG 140
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCASS 615
EL G+ + +L R++A ++ F + +I +D F DQ A++
Sbjct: 141 QELIGRRVGLLGFGNIARKIARKLCGFDVEVIAYDKF--PDQVAAT 184
>UniRef50_A0UAW1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=14; Burkholderiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Burkholderia multivorans ATCC 17616
Length = 452
Score = 80.6 bits (190), Expect = 3e-14
Identities = 40/109 (36%), Positives = 57/109 (52%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
D ID D+A +G+ V A GANA + E L+L A+ V ++ G WD+A +
Sbjct: 220 DVIDQDAAAARGIAVRAAVGANAAAVAEHAWALILACAKSVPQLDMRMREGHWDKATHKS 279
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCASSIAP 624
EL G+TL ++ L GR VA AFGM ++ FDPF ++ P
Sbjct: 280 VELDGRTLGLVGLGAIGRRVAAIGVAFGMKVLAFDPFAKEAPAGVTLVP 328
>UniRef50_A0JVX0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Arthrobacter sp.
FB24|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Arthrobacter sp. (strain FB24)
Length = 319
Score = 79.8 bits (188), Expect = 5e-14
Identities = 42/113 (37%), Positives = 63/113 (55%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
D+IDV++A + G+ V+ APGAN+ ELT L+L +R + LK+G+W+R G
Sbjct: 95 DSIDVEAAERLGINVLTAPGANSQGVAELTIALILAGSRSIPWHDAQLKSGQWNRR--PG 152
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCASSIAPRWSW 636
+E++GK L ++ GR VAT GM +I FD + S P +SW
Sbjct: 153 NEVSGKVLGLIGCGQIGRRVATMALGLGMKVIAFDEYPVTSFAPS---PDFSW 202
>UniRef50_Q9RUU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Deinococci|Rep: D-3-phosphoglycerate dehydrogenase -
Deinococcus radiodurans
Length = 544
Score = 79.4 bits (187), Expect = 7e-14
Identities = 39/98 (39%), Positives = 58/98 (59%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID++ A ++G+ V+NAP +N +SA EL ++ AR + + +AG WDR + G
Sbjct: 92 DNIDLEYASRRGLLVLNAPESNNVSAAELAVMHLMAAARGLTRSDRKTRAGEWDRK-FLG 150
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFV 591
EL KTL I+ L G VA R MN++ +DP+V
Sbjct: 151 LELTDKTLGIVGLGRIGSIVADRAQGLHMNVVAYDPYV 188
Score = 38.7 bits (86), Expect = 0.12
Identities = 17/45 (37%), Positives = 28/45 (62%)
Frame = +2
Query: 125 LNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDEA 259
L+ G + + +EE L +P++DAL+ RS T+V +E+LD A
Sbjct: 33 LDHEGFQIDYQGNLEREETLRRLPDYDALITRSRTKVDRELLDAA 77
>UniRef50_A6ULR7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Sinorhizobium medicae
WSM419|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding - Sinorhizobium medicae WSM419
Length = 328
Score = 79.4 bits (187), Expect = 7e-14
Identities = 40/96 (41%), Positives = 58/96 (60%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
+N+D++SA ++GV V+ A GAN S EL L L +AR + +++A +W+R+ Y G
Sbjct: 79 NNVDIESATRRGVPVLIADGANGKSVAELAVGLALSVARKITTQDASIRARQWNRSAY-G 137
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDP 585
+ AGKT I+A GR VA + A M II FDP
Sbjct: 138 LQFAGKTAGIVAFGAIGRRVAEILRAMDMRIIAFDP 173
>UniRef50_Q97N23 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
Clostridiaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Clostridium acetobutylicum
Length = 305
Score = 79.0 bits (186), Expect = 9e-14
Identities = 37/92 (40%), Positives = 54/92 (58%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNIDV A KG+ V N P A++ S EL M ++R + A+ ++ G+W++ YTG
Sbjct: 79 DNIDVTYARDKGLTVNNTPNASSASVAELAIGHMFAVSRFINTANVTMRQGKWEKKAYTG 138
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNII 573
+E+ GKTL ++ REVA R A GM +I
Sbjct: 139 TEIFGKTLGLIGFGRIAREVAKRAEALGMKVI 170
Score = 42.3 bits (95), Expect = 0.009
Identities = 20/30 (66%), Positives = 25/30 (83%)
Frame = +2
Query: 170 KEELLMEIPNHDALVVRSATQVTKEVLDEA 259
K+ELL++I D LVVRSAT+VTKEV+D A
Sbjct: 32 KDELLVKIKEFDVLVVRSATKVTKEVIDAA 61
>UniRef50_A4MA79 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Petrotoga mobilis
SJ95|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Petrotoga mobilis SJ95
Length = 310
Score = 78.2 bits (184), Expect = 2e-13
Identities = 38/103 (36%), Positives = 60/103 (58%), Gaps = 1/103 (0%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNIDVD+A KG+ V+N PG N+LS EL ++L + RH+ + LK +W++ G
Sbjct: 76 DNIDVDTAKLKGITVLNTPGQNSLSVAELVIGMVLDIYRHITRGTIGLKNEQWEKKQLEG 135
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPF-VSADQ 603
EL+ KT I+ G+ +A + F N + +D F +SA++
Sbjct: 136 FELSQKTFGIIGFGYVGKNLAQLLKGFQTNTLVYDVFEISAEE 178
Score = 35.5 bits (78), Expect = 1.1
Identities = 17/36 (47%), Positives = 24/36 (66%)
Frame = +2
Query: 152 TKAKISKEELLMEIPNHDALVVRSATQVTKEVLDEA 259
T + K+ L +I D L+VRSAT+VTKE+L+ A
Sbjct: 27 TSEHLEKDVLKDKIKEIDVLIVRSATKVTKEILEHA 62
>UniRef50_Q8XPB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Clostridium perfringens|Rep: D-3-phosphoglycerate
dehydrogenase - Clostridium perfringens
Length = 301
Score = 77.8 bits (183), Expect = 2e-13
Identities = 40/95 (42%), Positives = 54/95 (56%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNIDV A + G+ V N P A++ S E+ M LAR + ++ +KAG W + Y G
Sbjct: 78 DNIDVQYAEQNGIKVRNTPNASSSSVAEIILAHMFSLARFLNQSNITMKAGLWKKKDYVG 137
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
EL GKTL I+ + G E+A + A GM II FD
Sbjct: 138 VELEGKTLGIIGMGRIGSELAKKCTALGMKIIYFD 172
Score = 36.3 bits (80), Expect = 0.62
Identities = 20/59 (33%), Positives = 32/59 (54%)
Frame = +2
Query: 83 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDEA 259
+L+ DG+ K L G T E+L +I D +V+RSAT++ +E++DEA
Sbjct: 4 ILLNDGLDKKAISNLEFLGFDVDTN-HYDIEDLKEKIKKVDCIVIRSATKIRRELIDEA 61
>UniRef50_A4YUP8 Cluster: Putative D-3-phosphoglycerate
dehydrogenase; n=1; Bradyrhizobium sp. ORS278|Rep:
Putative D-3-phosphoglycerate dehydrogenase -
Bradyrhizobium sp. (strain ORS278)
Length = 335
Score = 77.8 bits (183), Expect = 2e-13
Identities = 36/101 (35%), Positives = 57/101 (56%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNIDV++A ++G+ V A GAN+ S EL LM +AR + +K G WD+A G
Sbjct: 89 DNIDVEAADRRGIPVFVARGANSQSVAELAFALMFAVAREIPHLDARIKTGHWDKATTKG 148
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSAD 600
++L G++L ++ GR + + M + FDP++ AD
Sbjct: 149 AQLLGRSLGVIGFGEIGRILVGLVQPLHMEVRIFDPYMPAD 189
>UniRef50_A1IDH6 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Deltaproteobacteria|Rep: D-3-phosphoglycerate
dehydrogenase - Candidatus Desulfococcus oleovorans Hxd3
Length = 532
Score = 77.8 bits (183), Expect = 2e-13
Identities = 34/99 (34%), Positives = 57/99 (57%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+D+ +A K GV V+N P N ++ E T +M+ L R++ + +L++G+W++ G
Sbjct: 79 DNVDIPAATKHGVAVMNTPEGNVVTTAEHTIAMMMALTRNIPQGTLSLRSGQWEKKKLQG 138
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVS 594
E+ KTL ++ G VA R MN+I FDP ++
Sbjct: 139 REVFNKTLGVIGFGKIGSIVADRARQLKMNVIVFDPNIA 177
Score = 41.9 bits (94), Expect = 0.012
Identities = 23/58 (39%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
Frame = +2
Query: 83 VLIVDGVGAK-CAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 253
VL+ D + A + L N G A K + EEL I +DAL++RSAT+VT ++L+
Sbjct: 5 VLVSDTIDASGVSRLENESGFAVDVKTGLPPEELKSIIGQYDALIIRSATKVTADILE 62
>UniRef50_Q5WLJ2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Bacillus|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus clausii (strain KSM-K16)
Length = 316
Score = 77.4 bits (182), Expect = 3e-13
Identities = 38/98 (38%), Positives = 59/98 (60%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNIDVD+A K GV V N P AN + + +L+L LAR + + K G+W +L+ G
Sbjct: 79 DNIDVDAAKKHGVTVTNVPNANKHAVADFAFSLLLSLARQIPTGNEKTKKGKWP-SLF-G 136
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFV 591
+++ +TL I+ L G+EVA R F M ++ +DP++
Sbjct: 137 ADVYQQTLGIIGLGAIGKEVARRASGFSMTVLAYDPYI 174
>UniRef50_A6DQ00 Cluster: SerA; n=1; Lentisphaera araneosa
HTCC2155|Rep: SerA - Lentisphaera araneosa HTCC2155
Length = 522
Score = 77.0 bits (181), Expect = 4e-13
Identities = 37/104 (35%), Positives = 58/104 (55%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
+ ID+ A K + V+N PGAN+ + E +M+ AR + + +AG W +A G
Sbjct: 76 NTIDIQYARSKDITVMNTPGANSNAVAEEAVGMMISCARFFIEGDRSTRAGEWKKAQLQG 135
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCA 609
EL GKT+ I G+ +A R+ F ++I+ +DPFVS D+ A
Sbjct: 136 FELTGKTVGIAGFGNIGQLLAKRLSGFEVDILVYDPFVSEDKLA 179
>UniRef50_Q18XF4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Desulfitobacterium
hafniense|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Desulfitobacterium
hafniense (strain DCB-2)
Length = 320
Score = 76.6 bits (180), Expect = 5e-13
Identities = 39/95 (41%), Positives = 54/95 (56%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
D+ID+ +A +G+ V NAPG NA S +L ML LAR +V A + G W + G
Sbjct: 84 DSIDLKAAAARGITVANAPGTNANSVADLAFGFMLSLARQIVSADKRTRDGFWGTVM--G 141
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
++ GKTL +L L G+ V R F MNI+G+D
Sbjct: 142 KDVYGKTLGVLGLGQIGKGVIRRASGFDMNILGYD 176
>UniRef50_A1RDF9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=1; Arthrobacter
aurescens TC1|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Arthrobacter aurescens
(strain TC1)
Length = 329
Score = 76.6 bits (180), Expect = 5e-13
Identities = 37/102 (36%), Positives = 58/102 (56%), Gaps = 2/102 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW--DRALY 471
DN+D+ +A + V V + PG+N+ + E +L+L L R ++PA+ + AG W R
Sbjct: 74 DNVDIPAASEHSVWVTSTPGSNSNAVAEHVFSLLLSLTRRIIPAANRVLAGTWAEGRGDL 133
Query: 472 TGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSA 597
G EL+G+TL I+ G+ VAT FGM ++ DP +A
Sbjct: 134 VGFELSGRTLGIVGFGAIGKRVATIANGFGMRVLASDPIATA 175
>UniRef50_Q88ZU6 Cluster: Phosphoglycerate dehydrogenase; n=2;
Lactobacillus|Rep: Phosphoglycerate dehydrogenase -
Lactobacillus plantarum
Length = 392
Score = 76.2 bits (179), Expect = 6e-13
Identities = 40/110 (36%), Positives = 62/110 (56%), Gaps = 9/110 (8%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST---------ALKAG 450
+NI +D A G V N PG+NA + EL L+++ +R+++ A+T +
Sbjct: 60 NNIPIDQATANGTAVFNTPGSNANAVKELIIGLLIMASRNLIAATTYSAQHTEADISQRT 119
Query: 451 RWDRALYTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSAD 600
D+ + G EL GKTLA++ L G VA + GMN+IG+DP++SAD
Sbjct: 120 EHDKTQFNGIELTGKTLAVIGLGHVGALVANAALSLGMNVIGYDPYLSAD 169
>UniRef50_Q46VE6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=6;
Proteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Ralstonia
eutropha (strain JMP134) (Alcaligenes eutrophus)
Length = 312
Score = 76.2 bits (179), Expect = 6e-13
Identities = 40/102 (39%), Positives = 53/102 (51%), Gaps = 1/102 (0%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA-LYT 474
DNIDV + +G+ VI A GANA S E T +L R S + G+W RA L
Sbjct: 78 DNIDVAACRDRGIRVIPASGANARSVAEYVVTTAALLLRGAYLGSAEVAGGKWPRARLSE 137
Query: 475 GSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSAD 600
G E GKTL ++ GR+ A AFGM ++ DP ++ D
Sbjct: 138 GREALGKTLGLIGFGDIGRQAAALAQAFGMRVVAHDPMLAPD 179
>UniRef50_Q6W1I8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Rhizobium sp. NGR234|Rep: D-3-phosphoglycerate
dehydrogenase - Rhizobium sp. (strain NGR234)
Length = 327
Score = 74.9 bits (176), Expect = 1e-12
Identities = 42/110 (38%), Positives = 62/110 (56%), Gaps = 5/110 (4%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR-ALYT 474
D+ID D+A + GVG+ PG NA + + T ++L L R VV A+KAGRWDR T
Sbjct: 82 DSIDHDAAKEFGVGISVTPGMNAETVADQTLAMILGLMRRVVTQDQAVKAGRWDRVGEAT 141
Query: 475 GSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFV----SADQCAS 612
+EL KT+ ++ G+ V R+ FG+ ++ FD V A++C S
Sbjct: 142 PTELYRKTVGLIGAGIIGKAVIRRLLGFGVRVLYFDAMVEKVHGAERCGS 191
>UniRef50_Q0K073 Cluster: D-3-Phosphoglycerate dehydrogenase; n=2;
Burkholderiales|Rep: D-3-Phosphoglycerate dehydrogenase
- Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428
/ Stanier 337)(Cupriavidus necator (strain ATCC 17699 /
H16 / DSM 428 / Stanier337))
Length = 360
Score = 73.3 bits (172), Expect = 4e-12
Identities = 39/106 (36%), Positives = 59/106 (55%), Gaps = 1/106 (0%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 474
D ID+D+ + GV V+N G NA S E+T LML + R + + +L+A + R
Sbjct: 96 DTIDIDACTEAGVAVLNQAGGNADSVAEMTLGLMLAVLRRIAESDRSLRAHNCESREDLM 155
Query: 475 GSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCAS 612
G EL G+TL ++ + GR VA A GM +IG DP + A + ++
Sbjct: 156 GHELRGRTLGLVGVGHAGRRVAALGRALGMRVIGCDPALDAAELSA 201
>UniRef50_A7HEG1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=4; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase NAD-binding -
Anaeromyxobacter sp. Fw109-5
Length = 399
Score = 72.9 bits (171), Expect = 6e-12
Identities = 34/95 (35%), Positives = 57/95 (60%), Gaps = 1/95 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
+ IDV +A ++GV V N PG N+++ EL L++ L R + L+AG+WD+ ++
Sbjct: 74 NTIDVAAASRRGVYVANCPGQNSIAVAELAIGLVVALDRRIPDNVALLRAGKWDKKTFSE 133
Query: 478 SE-LAGKTLAILALAXXGREVATRMYAFGMNIIGF 579
++ L G+TL + + GREVA R A GM ++ +
Sbjct: 134 AQGLYGRTLGVAGVGSIGREVARRAQALGMRVVAW 168
>UniRef50_A6Q7Q2 Cluster: D-3-phosphoglycerate dehydrogenase; n=27;
Epsilonproteobacteria|Rep: D-3-phosphoglycerate
dehydrogenase - Sulfurovum sp. (strain NBC37-1)
Length = 529
Score = 72.9 bits (171), Expect = 6e-12
Identities = 37/99 (37%), Positives = 54/99 (54%), Gaps = 1/99 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR-WDRALYT 474
DN+D+ + K+G+ V+N P AN ++A ELT ML R A LK R W R +
Sbjct: 80 DNVDIPGSSKQGIVVMNVPTANTIAAVELTLAHMLSCVRQFPYAHNNLKLDRVWRRQDWY 139
Query: 475 GSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFV 591
G+EL K L I+ G V R AF M+++ +DP++
Sbjct: 140 GTELKDKKLGIIGFGNIGSRVGKRAKAFEMDVLAYDPYI 178
>UniRef50_A5URV2 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Roseiflexus sp.
RS-1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Roseiflexus sp. RS-1
Length = 323
Score = 71.7 bits (168), Expect = 1e-11
Identities = 40/106 (37%), Positives = 56/106 (52%), Gaps = 1/106 (0%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID+ +A K+G+ VIN P S E L+L LA+ VV + L+ W A G
Sbjct: 80 DNIDIAAATKRGILVINTPDGPTESTAEHAVALLLALAKQVVASDRVLRTEGWRAARLRG 139
Query: 478 SELAGKTLAILALAXXGREVA-TRMYAFGMNIIGFDPFVSADQCAS 612
E+ GKTL I+ L GR VA GM+++ +DP V + A+
Sbjct: 140 IEVRGKTLGIVGLGRIGRRVAQICRQGLGMHVVAYDPPVPDETFAT 185
>UniRef50_Q81T55 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=41; cellular
organisms|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Bacillus anthracis
Length = 323
Score = 71.3 bits (167), Expect = 2e-11
Identities = 38/99 (38%), Positives = 51/99 (51%), Gaps = 3/99 (3%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA---GRWDRAL 468
DNID AG+KG+ V N P + + ELT L+L AR + T + W
Sbjct: 77 DNIDYTYAGEKGIAVTNTPKVSTEATAELTFALLLAAARRIPEGDTLCRTTGFNGWAPLF 136
Query: 469 YTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDP 585
+ G E+ GKT+ I+ L G+ VA R AFGMNI+ P
Sbjct: 137 FLGREVHGKTIGIIGLGEIGKAVAKRAKAFGMNILYTGP 175
>UniRef50_Q031D4 Cluster: Phosphoglycerate dehydrogenase; n=20;
Streptococcaceae|Rep: Phosphoglycerate dehydrogenase -
Lactococcus lactis subsp. cremoris (strain SK11)
Length = 398
Score = 70.9 bits (166), Expect = 2e-11
Identities = 38/112 (33%), Positives = 64/112 (57%), Gaps = 11/112 (9%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DRAL-- 468
+NI ++ KG+ V NAPG NA + EL ++M+ R++ PA+ L + D+A+
Sbjct: 64 NNIPIEKCASKGIVVFNAPGGNANAVKELVLSMMIFGTRNLKPANKWLTGQKGNDKAIDV 123
Query: 469 --------YTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSAD 600
++GSE++GKTL ++ L G +VA GM +IG+DP++S +
Sbjct: 124 AVENGKKAFSGSEISGKTLGVIGLGNIGSKVANDAQRLGMKVIGYDPYLSIE 175
>UniRef50_Q3KBX8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Pseudomonas|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Pseudomonas fluorescens (strain PfO-1)
Length = 324
Score = 70.5 bits (165), Expect = 3e-11
Identities = 39/98 (39%), Positives = 52/98 (53%), Gaps = 2/98 (2%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW--DRALY 471
DN+D +A + GV V N PGAN S E L+L ++R V A+ + W DR
Sbjct: 74 DNVDYKAAAELGVWVTNTPGANRRSVVEHVFALLLGISRKVQLATDQTRNNIWAQDRLSL 133
Query: 472 TGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDP 585
TG EL G+TL ++ GR VA AFGM ++ DP
Sbjct: 134 TGIELEGRTLGLIGFGDIGRHVAPVAEAFGMKVLATDP 171
>UniRef50_Q21A61 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Rhodopseudomonas
palustris BisB18|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Rhodopseudomonas palustris
(strain BisB18)
Length = 321
Score = 70.5 bits (165), Expect = 3e-11
Identities = 37/100 (37%), Positives = 53/100 (53%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
++ID+ +A GV V+ A GANA S E LML L + V ++ G WD+ Y G
Sbjct: 81 NDIDLAAAKALGVPVLAAVGANAHSVAEHAFMLMLALIKDVRNQDAYVRGGGWDKKGYRG 140
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSA 597
EL G+ L ++ + GR +A + GM I +DPF A
Sbjct: 141 RELRGRVLGLVGIGMIGRALAAMVQPIGMTTIAYDPFAPA 180
>UniRef50_Q0FX01 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding subunit; n=3;
Rhodobacteraceae|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding subunit - Roseovarius sp.
HTCC2601
Length = 326
Score = 70.5 bits (165), Expect = 3e-11
Identities = 35/97 (36%), Positives = 53/97 (54%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID+ + + G+ V N P ANA + EL LM +AR + ++ AG WDR + G
Sbjct: 84 DNIDIPACTEAGLPVCNTPAANADAVAELAVGLMFSMARWIPQGHASVTAGGWDRRI--G 141
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPF 588
++L GKTL I+ L G+ +A GM ++ D +
Sbjct: 142 TQLGGKTLGIVGLGNIGKRLAKLARGLGMQVVATDKY 178
>UniRef50_A7CY19 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Opitutaceae bacterium
TAV2|Rep: D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Opitutaceae bacterium TAV2
Length = 318
Score = 70.5 bits (165), Expect = 3e-11
Identities = 37/95 (38%), Positives = 54/95 (56%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
D IDV A K + V+ PG N + E T L+L L ++++ + + ++G W R TG
Sbjct: 81 DKIDVAHATSKKIPVLFTPGVNHTTVAEHTFLLLLALEKNILFHTDSTRSGGWKRK--TG 138
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
EL KT+ I+ L G+EVA R AFGM +I +D
Sbjct: 139 HELLAKTIGIVGLGRIGKEVAIRARAFGMEVIAYD 173
>UniRef50_A6UCB8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Sinorhizobium|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Sinorhizobium medicae WSM419
Length = 310
Score = 70.5 bits (165), Expect = 3e-11
Identities = 37/98 (37%), Positives = 58/98 (59%), Gaps = 1/98 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA-LKAGRWDRALYT 474
DN+ + ++G+G++ A GANA+ EL+ LML RH +PA TA ++AG W R+
Sbjct: 82 DNLPLPLLKERGIGILKAEGANAVGVAELSVGLMLAALRH-IPAETAGIRAGGWPRS--R 138
Query: 475 GSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPF 588
G E+A +T+ I+ G+ VA + A ++I DPF
Sbjct: 139 GREIAERTVGIIGCGAIGKRVARAVSAMRASVIACDPF 176
>UniRef50_A6CKS4 Cluster: Putative uncharacterized protein; n=1;
Bacillus sp. SG-1|Rep: Putative uncharacterized protein
- Bacillus sp. SG-1
Length = 322
Score = 70.5 bits (165), Expect = 3e-11
Identities = 38/109 (34%), Positives = 64/109 (58%), Gaps = 2/109 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 474
DNID+++A +G+ V NAP AN + E TL+L +R ++ +AL+ G ++ R
Sbjct: 76 DNIDLEAASDRGILVTNAPFANVNAVAEHVLTLILSGSRQLIQVDSALRNGDFEVRNRKF 135
Query: 475 GSELAGKTLAILALAXXGREVATRM-YAFGMNIIGFDPFVSADQCASSI 618
G EL GKTL ++ G+ VA + Y GM+++ +DP+V + +S +
Sbjct: 136 GIELKGKTLGVVGFGNIGQLVAEKCHYGLGMDVLVYDPYVREENVSSYV 184
>UniRef50_A7HM61 Cluster: Glyoxylate reductase; n=1;
Fervidobacterium nodosum Rt17-B1|Rep: Glyoxylate
reductase - Fervidobacterium nodosum Rt17-B1
Length = 317
Score = 70.1 bits (164), Expect = 4e-11
Identities = 32/98 (32%), Positives = 58/98 (59%), Gaps = 3/98 (3%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRAL 468
+NID+++A ++G+ V N PG + ++ L+L +AR +V + ++ G+ W L
Sbjct: 77 NNIDIEAAKERGIYVTNTPGVLTEATADIAFALILAVARRIVESDKFVREGKFVGWKPKL 136
Query: 469 YTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
+ G +L GKTL ++ + G+ VA R FGMNI+ ++
Sbjct: 137 FLGYDLYGKTLGVIGMGRIGQAVARRALGFGMNIVYYN 174
>UniRef50_A4WXD4 Cluster: Dimethylmenaquinone methyltransferase;
n=1; Rhodobacter sphaeroides ATCC 17025|Rep:
Dimethylmenaquinone methyltransferase - Rhodobacter
sphaeroides ATCC 17025
Length = 334
Score = 69.7 bits (163), Expect = 5e-11
Identities = 30/97 (30%), Positives = 52/97 (53%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID+ +A +G+ V+ + G+N+ + E L L+L + + P + A+K G W + + G
Sbjct: 89 DNIDLAAAEARGIPVLRSMGSNSRAVAEHAIALALMLVKEIQPLNAAVKGGAWPKPTFIG 148
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPF 588
+ G L ++ GRE A A GM ++ DP+
Sbjct: 149 KDFQGAMLGLVGYGGIGRETARMAEALGMEVVVHDPY 185
>UniRef50_Q3CIY1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=2;
Thermoanaerobacter ethanolicus|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Thermoanaerobacter ethanolicus ATCC 33223
Length = 319
Score = 69.3 bits (162), Expect = 7e-11
Identities = 36/95 (37%), Positives = 56/95 (58%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
D+IDV +A + G+ V NAPG N+ +L L+ +LAR + A+T K G+W + + G
Sbjct: 84 DSIDVKTANQLGIVVTNAPGTNSEEVADLAFGLLHMLARGLYQANTDTKNGKWIKPV--G 141
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
L+ KT+ I+ + G VA R + MNI+G+D
Sbjct: 142 ISLSKKTIGIIGVGTIGTAVAKRATGYDMNILGYD 176
>UniRef50_Q03YV3 Cluster: Lactate dehydrogenase related enzyme; n=1;
Leuconostoc mesenteroides subsp. mesenteroides ATCC
8293|Rep: Lactate dehydrogenase related enzyme -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 314
Score = 69.3 bits (162), Expect = 7e-11
Identities = 32/98 (32%), Positives = 58/98 (59%), Gaps = 1/98 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 474
D +DVD+A ++G+ V+N P A + S E + +L +++++ S A+ W+ R +
Sbjct: 76 DAVDVDAATQRGIYVVNTPKALSGSVAETAVSELLAISKNLYQDSKAIHDDNWNYRKAHP 135
Query: 475 GSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPF 588
G ++ GKT+ IL G++VA ++ F + +I FDPF
Sbjct: 136 GRDIEGKTVGILGFGRIGQQVAKKLSGFDVKVIAFDPF 173
>UniRef50_A7NGZ0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Roseiflexus castenholzii
DSM 13941|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding - Roseiflexus castenholzii DSM
13941
Length = 345
Score = 69.3 bits (162), Expect = 7e-11
Identities = 38/106 (35%), Positives = 53/106 (50%), Gaps = 1/106 (0%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID+ +A ++G+ VIN P S E L+L LA+ VV A + W A G
Sbjct: 81 DNIDLAAATERGILVINTPDGPTESTAEHAVALVLALAKQVVAADHRFRTAGWSAARLRG 140
Query: 478 SELAGKTLAILALAXXGREVA-TRMYAFGMNIIGFDPFVSADQCAS 612
E+ GKTL ++ L GR VA GM + +DP A+ A+
Sbjct: 141 VEVRGKTLGVVGLGRIGRRVAQICRQGLGMRVAAYDPLAPAEAFAA 186
>UniRef50_Q5KN70 Cluster: D-3-phosphoglycerate dehydrogenase 2,
putative; n=2; Filobasidiella neoformans|Rep:
D-3-phosphoglycerate dehydrogenase 2, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 508
Score = 69.3 bits (162), Expect = 7e-11
Identities = 30/95 (31%), Positives = 57/95 (60%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
+ +D++ A K+G+ V N+P +N+ S EL + ++ L+R ++ + ++AG W++
Sbjct: 174 NQVDLEHAAKRGIAVFNSPFSNSRSVAELVISEIIALSRQIIDRTHEMRAGIWNKLSKNC 233
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
E+ GKTL I+ G +++ AFGM++I FD
Sbjct: 234 WEIRGKTLGIVGYGHIGSQLSVLAEAFGMSVIYFD 268
Score = 40.3 bits (90), Expect = 0.038
Identities = 19/59 (32%), Positives = 39/59 (66%), Gaps = 2/59 (3%)
Frame = +2
Query: 83 VLIVDGVGAKCAELLNAYG--IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 253
+L+++ + A+ L + G + TKA ++EEL+ ++PN+ A+ +RS T++T +V+D
Sbjct: 101 ILLLENINLDAADYLKSQGYEVDHVTKA-YTEEELIAKLPNYHAIGIRSKTKITAKVID 158
>UniRef50_A1AR04 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Pelobacter propionicus
DSM 2379|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Pelobacter propionicus
(strain DSM 2379)
Length = 357
Score = 68.9 bits (161), Expect = 9e-11
Identities = 32/93 (34%), Positives = 55/93 (59%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+DV+ A K+GV ++ P +A + E+ ML L+R ++ A +++ GRW++ ++G
Sbjct: 97 DNLDVEYARKRGVQLVRIPQPSARAVAEMAFAFMLALSRRLLEADRSMRNGRWEKHEFSG 156
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIG 576
L KTL ++ + G VA A+GM +IG
Sbjct: 157 YLLRDKTLGVVGIGNTGSCVAQMGVAWGMRVIG 189
>UniRef50_O86322 Cluster: POSSIBLE D-3-PHOSPHOGLYCERATE
DEHYDROGENASE SERA2; n=11; Mycobacterium|Rep: POSSIBLE
D-3-PHOSPHOGLYCERATE DEHYDROGENASE SERA2 - Mycobacterium
tuberculosis
Length = 326
Score = 68.5 bits (160), Expect = 1e-10
Identities = 33/102 (32%), Positives = 56/102 (54%), Gaps = 6/102 (5%)
Frame = +1
Query: 301 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR------ 462
N+D+ A G+ V++ P NA + E+T L+L +ARH++PA +++G R
Sbjct: 86 NVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVARHLIPADADVRSGNIFRDGTIPY 145
Query: 463 ALYTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPF 588
+ G+E+AG T ++ L GR V R+ G+ +I DP+
Sbjct: 146 QRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLRVIAHDPY 187
>UniRef50_A1W9A3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Acidovorax sp.
JS42|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Acidovorax sp. (strain JS42)
Length = 339
Score = 68.5 bits (160), Expect = 1e-10
Identities = 34/100 (34%), Positives = 54/100 (54%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
D+ID+++ K+G+ V + P + S E L+L + RH+ A + G + TG
Sbjct: 83 DHIDLEACRKRGIAVCHVPDYGSASVAEHAFALLLGVTRHLTQAHERARQGSFAYRGLTG 142
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSA 597
EL G+TL I+ L GR VA FGM+++ +DP +A
Sbjct: 143 FELEGRTLGIVGLGRIGRHVARIAVGFGMDVLAYDPAFAA 182
>UniRef50_A0JWH0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=14; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Arthrobacter sp. (strain FB24)
Length = 322
Score = 68.5 bits (160), Expect = 1e-10
Identities = 40/105 (38%), Positives = 60/105 (57%)
Frame = +1
Query: 301 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGS 480
+ID+ +A + G+ V+ G + +A ELT L+L LAR + L+ GRW + G
Sbjct: 84 SIDLRAAEELGI-VVCGTGGSPTAAPELTWGLLLALARSISFEDRNLREGRWQSTV--GF 140
Query: 481 ELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCASS 615
ELAGKTL +L L GR VA AFGM++I + P ++ + A +
Sbjct: 141 ELAGKTLGVLGLGKIGRRVAAYGQAFGMDVIAWSPNLTGEAAAQA 185
>UniRef50_Q8Y3L1 Cluster: Lmo2824 protein; n=14; Bacillales|Rep:
Lmo2824 protein - Listeria monocytogenes
Length = 395
Score = 68.1 bits (159), Expect = 2e-10
Identities = 39/111 (35%), Positives = 60/111 (54%), Gaps = 10/111 (9%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD------ 459
+NI V++ +KG+ V N PGANA + EL + V AR ++ + +K +
Sbjct: 61 NNIPVENCSEKGIVVFNTPGANANAVKELVLASLFVSARPILEGTEWVKELPAEDDVEQK 120
Query: 460 ----RALYTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSAD 600
+ + G+ELAGK L I+ L G VA + GM+++G+DPFVS D
Sbjct: 121 VEAGKKAFAGTELAGKKLGIIGLGAIGALVANDALSLGMDVVGYDPFVSVD 171
>UniRef50_Q3SK87 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=4; Proteobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Thiobacillus
denitrificans (strain ATCC 25259)
Length = 391
Score = 68.1 bits (159), Expect = 2e-10
Identities = 39/112 (34%), Positives = 59/112 (52%), Gaps = 11/112 (9%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL-----------K 444
+NI V ++G+ V NAPGANA + EL ML+ AR++VPA + K
Sbjct: 64 NNIPVKKMSERGLPVFNAPGANANAVKELVIAGMLMGARNLVPALKFVESLDGTDEAMHK 123
Query: 445 AGRWDRALYTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSAD 600
A + + G EL G+TL ++ L G +A GMN++G+DP ++ D
Sbjct: 124 ATEAGKKQFAGMELPGRTLGVIGLGAIGSHIAEAAIRLGMNVVGYDPAITVD 175
>UniRef50_Q0RXU8 Cluster: Phosphoglycerate dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: Phosphoglycerate dehydrogenase
- Rhodococcus sp. (strain RHA1)
Length = 325
Score = 68.1 bits (159), Expect = 2e-10
Identities = 38/104 (36%), Positives = 51/104 (49%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNIDV A + GV V+ GANA+S E T + L R V + G W+R G
Sbjct: 83 DNIDVKCANEAGVVVVAPLGANAISVAEHTIGMALAAVRRTVELDADCRRGGWERT--PG 140
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCA 609
EL G +L GR A + GM+I+ +DPF A++ A
Sbjct: 141 RELHGGVWGLLGAGATGRACARLARSLGMSIVAYDPFADAEKLA 184
>UniRef50_Q4WHR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Aspergillus fumigatus|Rep: D-3-phosphoglycerate
dehydrogenase - Aspergillus fumigatus (Sartorya
fumigata)
Length = 635
Score = 68.1 bits (159), Expect = 2e-10
Identities = 29/70 (41%), Positives = 49/70 (70%)
Frame = +1
Query: 307 DVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSEL 486
DV+ A K G+ V+N+P N +A E T L++ +AR++ A ++LK+G+W+R+ + G E+
Sbjct: 109 DVEEATKLGIVVVNSPSGNIGAAAEHTIALLMAMARNIPEACSSLKSGKWERSKFVGVEV 168
Query: 487 AGKTLAILAL 516
GKTL+I+ L
Sbjct: 169 KGKTLSIIGL 178
Score = 33.9 bits (74), Expect = 3.3
Identities = 21/59 (35%), Positives = 32/59 (54%)
Frame = +2
Query: 83 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDEA 259
VL+ + + LL A + + + +ELL IP ++ALVVRS T+VT +L A
Sbjct: 11 VLVPEKLSPDGLALLRA-SLEVDERRGLDADELLQIIPEYEALVVRSETKVTANLLRAA 68
>UniRef50_Q97ZK1 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Sulfolobaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Sulfolobus solfataricus
Length = 326
Score = 68.1 bits (159), Expect = 2e-10
Identities = 36/95 (37%), Positives = 53/95 (55%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID + A K+ + ++ APGA+ SA ELT L++ AR + + K G + + G
Sbjct: 92 DNIDTEEASKRNIKIVYAPGASTDSAAELTIGLLIAAARKLYDSMNMAKGGIFKK--IEG 149
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
ELAGKT+ I+ G +VA A MN+I +D
Sbjct: 150 IELAGKTIGIVGFGRIGTKVAKVCKALDMNVIAYD 184
Score = 41.1 bits (92), Expect = 0.022
Identities = 24/61 (39%), Positives = 34/61 (55%)
Frame = +2
Query: 68 VDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEV 247
+D K VLI D V L G+ K +I++EELL I + L+VRS T+V KE+
Sbjct: 16 LDFK-VLITDPVDQYMIRTLQNNGLIVDYKPEITREELLKIIDQYQVLIVRSRTKVDKEI 74
Query: 248 L 250
+
Sbjct: 75 I 75
>UniRef50_A4YFM2 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Metallosphaera sedula
DSM 5348|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Metallosphaera sedula DSM
5348
Length = 324
Score = 68.1 bits (159), Expect = 2e-10
Identities = 32/102 (31%), Positives = 57/102 (55%), Gaps = 3/102 (2%)
Frame = +1
Query: 304 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL---YT 474
+D+ +A ++ + + PG N+++ ELT L + L R V+P + ++KAG+W
Sbjct: 85 VDLKAAKERDIIITYNPGGNSVAVAELTIMLAIALYRKVIPLALSVKAGKWSELKPKDTM 144
Query: 475 GSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSAD 600
G EL GK IL G+ VA + + ++G+DP+VS++
Sbjct: 145 GHELEGKAWGILGFGNIGKRVAQLVTSLNCKVLGYDPYVSSE 186
>UniRef50_Q825H6 Cluster: Putative glycerate dehydrogenase; n=1;
Streptomyces avermitilis|Rep: Putative glycerate
dehydrogenase - Streptomyces avermitilis
Length = 325
Score = 67.7 bits (158), Expect = 2e-10
Identities = 41/96 (42%), Positives = 55/96 (57%), Gaps = 4/96 (4%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVIN--APGANALSACELTCTLMLVLARHVVPASTALKAGRW--DRA 465
D +D+D+A +G+ V N + GA + E T LML LA+ +VPA TAL W R
Sbjct: 82 DYVDLDAARARGLPVCNIGSSGAEQQNVAEQTFALMLALAKQLVPAHTALVDADWALPRL 141
Query: 466 LYTGSELAGKTLAILALAXXGREVATRMYAFGMNII 573
+ +EL+GKTL I+ L G EVA R AF M I+
Sbjct: 142 QRSITELSGKTLGIVGLGHIGEEVARRAVAFDMRIV 177
>UniRef50_A4FHH0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 336
Score = 67.7 bits (158), Expect = 2e-10
Identities = 35/92 (38%), Positives = 51/92 (55%), Gaps = 1/92 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
+ ID +SA ++GV V N PG NA++ EL LML L R V L+AGRWD+ Y+
Sbjct: 74 NTIDCESAAERGVHVCNVPGRNAIAVAELAFALMLALDRSVCDNVDDLRAGRWDKKRYSR 133
Query: 478 SE-LAGKTLAILALAXXGREVATRMYAFGMNI 570
+ + G+ + ++ L G A R AFG +
Sbjct: 134 ARGIHGRRVGVVGLGQIGLAFAERAAAFGATV 165
>UniRef50_Q1CG62 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=8; Yersinia|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Yersinia pestis (biovar Antiqua strain
Nepal516)
Length = 316
Score = 67.3 bits (157), Expect = 3e-10
Identities = 35/108 (32%), Positives = 55/108 (50%), Gaps = 2/108 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW--DRALY 471
DNID+ +A K+G+ + N P + + L LAR + +++GRW D+ +
Sbjct: 77 DNIDLSAARKRGMRICNVPDYGIEEVADHAAAMTLALARKLGRYEAGIRSGRWEIDQMVD 136
Query: 472 TGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCASS 615
L T+ ++ L R ATRM FG IIGFDP+V+ + S+
Sbjct: 137 GVRSLRDTTVGLIGLGRIARAYATRMAVFGCRIIGFDPYVTETEARSA 184
>UniRef50_A6T665 Cluster: Putative D-3-phosphoglycerate
dehydrogenase; n=1; Klebsiella pneumoniae subsp.
pneumoniae MGH 78578|Rep: Putative D-3-phosphoglycerate
dehydrogenase - Klebsiella pneumoniae subsp. pneumoniae
MGH 78578
Length = 342
Score = 67.3 bits (157), Expect = 3e-10
Identities = 47/126 (37%), Positives = 63/126 (50%), Gaps = 26/126 (20%)
Frame = +1
Query: 301 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR--------- 453
NID +A +G+ V+ PG NA +A ELT LML LARH+ + ALK G
Sbjct: 79 NIDTQAAQARGIRVLYTPGRNADAAAELTLGLMLSLARHIPQSHAALKRGEFTQADNASA 138
Query: 454 -----------WDRA------LYTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
WD + ++ GSEL KTL ++ GR VA AFGM ++ D
Sbjct: 139 ATQQGLRRDVVWDVSPESPYEVFKGSELRNKTLGLVGYGNIGRRVARIARAFGMAVLVVD 198
Query: 583 PFVSAD 600
PFV+A+
Sbjct: 199 PFVAAE 204
>UniRef50_A4FK85 Cluster: D-3-phosphoglycerate dehydrogenase,
putative; n=1; Saccharopolyspora erythraea NRRL
2338|Rep: D-3-phosphoglycerate dehydrogenase, putative -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 352
Score = 67.3 bits (157), Expect = 3e-10
Identities = 37/108 (34%), Positives = 55/108 (50%), Gaps = 4/108 (3%)
Frame = +1
Query: 301 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY--- 471
N+D+ +A + GV V APG NA +A E L+L R + + LK+G W Y
Sbjct: 100 NVDLQAATEAGVVVSYAPGRNAAAAAEFAVGLVLAALRRIPASDAELKSGNWRGDYYAYE 159
Query: 472 -TGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCAS 612
G EL G T+ ++ GR VA + AFG +++ DPFV + +
Sbjct: 160 NAGIELEGSTVGLVGYGAIGRIVARVLAAFGAHVLVADPFVKPEDATA 207
>UniRef50_A0RW58 Cluster: Phosphoglycerate dehydrogenase; n=3;
Crenarchaeota|Rep: Phosphoglycerate dehydrogenase -
Cenarchaeum symbiosum
Length = 310
Score = 67.3 bits (157), Expect = 3e-10
Identities = 36/95 (37%), Positives = 49/95 (51%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID+ +A GV VINA + EL +ML +AR + A ++ G+W + G
Sbjct: 79 DNIDLAAAESAGVRVINAVEGATTAVSELVLGMMLCMARQIPRADRGIRGGKWLKGELGG 138
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
+EL GK L I+ L GR + MNIIG D
Sbjct: 139 TELKGKYLGIVGLGNIGRRLGRLARGMNMNIIGHD 173
Score = 41.5 bits (93), Expect = 0.016
Identities = 20/61 (32%), Positives = 33/61 (54%)
Frame = +2
Query: 77 KSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDE 256
++VLI D +L G+ + K +I+ EEL E P + ++VRS T +T E++
Sbjct: 5 ETVLICDKADPVLGRILQQNGLRVSYKPEITPEELAAEAPGYSIIIVRSRTTITGEIIRS 64
Query: 257 A 259
A
Sbjct: 65 A 65
>UniRef50_Q74CK1 Cluster: Glycerate dehydrogenase; n=12;
Bacteria|Rep: Glycerate dehydrogenase - Geobacter
sulfurreducens
Length = 327
Score = 66.9 bits (156), Expect = 4e-10
Identities = 42/107 (39%), Positives = 58/107 (54%), Gaps = 6/107 (5%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW----DRA 465
+N+DV++AGK+G+ V N P + S + T L+L LA HV +A+KA W D +
Sbjct: 81 NNVDVEAAGKRGIPVANIPAYSTESVVQTTFALLLELAVHVGIHDSAVKAREWVRSPDHS 140
Query: 466 LYTGS--ELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSAD 600
+ EL G TL I+ GR VA AFGM I+ + P V AD
Sbjct: 141 FWKTPIVELDGLTLGIVGYGTIGRAVARVGAAFGMKIMAYAPRVPAD 187
>UniRef50_Q39LG4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=2; Burkholderia|Rep: D-isomer specific
2-hydroxyacid dehydrogenase - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 312
Score = 66.9 bits (156), Expect = 4e-10
Identities = 31/91 (34%), Positives = 50/91 (54%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
+N+DV +A ++G+ V +APG NA + + ++L LAR P + A++AGRW +
Sbjct: 77 ENVDVAAAARRGIVVAHAPGTNASTVADHAIGMLLALARGYAPLTGAVRAGRWHASRAAR 136
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNI 570
L G L ++ + GR VA R F M +
Sbjct: 137 PTLTGAALGVIGMGRIGRLVAARAQGFDMTL 167
>UniRef50_Q0ETU3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Thermoanaerobacter
ethanolicus X514|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Thermoanaerobacter
ethanolicus X514
Length = 324
Score = 66.9 bits (156), Expect = 4e-10
Identities = 36/100 (36%), Positives = 56/100 (56%), Gaps = 2/100 (2%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 474
DNIDV++A +KG+ V N P N LS E T ++L L++ + A+++G W R
Sbjct: 75 DNIDVNAATEKGILVCNLPAVNNLSVAEHTIAMILNLSKQLSLMDKAVRSGNWGARNSNI 134
Query: 475 GSELAGKTLAILALAXXGREVATRMY-AFGMNIIGFDPFV 591
E+ GK L I+ + G VA + + GM I+ +DP+V
Sbjct: 135 SVEIEGKVLGIVGMGNIGSLVAKKCHDGLGMKIVAYDPYV 174
>UniRef50_A7CR80 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Opitutaceae bacterium
TAV2|Rep: D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Opitutaceae bacterium TAV2
Length = 355
Score = 66.9 bits (156), Expect = 4e-10
Identities = 33/109 (30%), Positives = 53/109 (48%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+D + + G+ + N PG ++ ++ LAR +KAG W ++ G
Sbjct: 125 DNVDFAACQRLGLPISNTPGMFGREVADVAVGYVIALARQTFAIDRTVKAGGWIKS--AG 182
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCASSIAP 624
LAGKT+A+ GR A R++A M I+ +DPF A ++ P
Sbjct: 183 ISLAGKTVALAGFGDIGRNTARRLFAAEMKIVAYDPFFKAASGLEAVEP 231
>UniRef50_A4FIJ9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 322
Score = 66.9 bits (156), Expect = 4e-10
Identities = 36/99 (36%), Positives = 50/99 (50%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
D +D +A ++G+ V N PG NA + + T ML L RH ++ G W G
Sbjct: 85 DGVDHVAAAERGIPVANLPGFNADAVADWTVGAMLHLLRHYAAGHRKVEQGGWGPEGLRG 144
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVS 594
+L+ T+AIL GR VA R+ FG I+ DPF S
Sbjct: 145 RDLSALTVAILGFGNIGRAVARRLDGFGAEIVVHDPFPS 183
>UniRef50_A5V6T9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Sphingomonas wittichii
RW1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Sphingomonas wittichii RW1
Length = 317
Score = 66.5 bits (155), Expect = 5e-10
Identities = 36/111 (32%), Positives = 58/111 (52%), Gaps = 3/111 (2%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD---RAL 468
D+ID+D+ +G+ + N PG + + + L+L R + A+ L+ GRW +
Sbjct: 80 DHIDLDAVRARGLPMFNTPGILSNAVADQAMLLLLAATRRMAEATALLREGRWTDLWSSH 139
Query: 469 YTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCASSIA 621
G ELAG+TL I L GR VA R AFGM ++ + + D+ ++ A
Sbjct: 140 ILGVELAGRTLGIYGLGDIGRRVARRATAFGMRLVYHNRRRAVDEAGATFA 190
>UniRef50_O28495 Cluster: 2-hydroxyacid dehydrogenase, putative;
n=4; Archaea|Rep: 2-hydroxyacid dehydrogenase, putative
- Archaeoglobus fulgidus
Length = 323
Score = 66.5 bits (155), Expect = 5e-10
Identities = 38/98 (38%), Positives = 54/98 (55%), Gaps = 3/98 (3%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR---AL 468
+NIDV++A K + V N G NALS E T L L R ++ A ++ +GRW++ A
Sbjct: 82 NNIDVEAAKKLSITVANVGGVNALSVAEHTVMFALALLRRLIYAHNSVLSGRWEQDEMAN 141
Query: 469 YTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
EL GKT I+ + GREV R+ +G+ II D
Sbjct: 142 LGVYELHGKTWGIIGMGAQGREVTKRLQGWGVKIIYHD 179
>UniRef50_UPI000050F9E4 Cluster: COG0111: Phosphoglycerate
dehydrogenase and related dehydrogenases; n=1;
Brevibacterium linens BL2|Rep: COG0111: Phosphoglycerate
dehydrogenase and related dehydrogenases -
Brevibacterium linens BL2
Length = 314
Score = 65.7 bits (153), Expect = 9e-10
Identities = 32/92 (34%), Positives = 48/92 (52%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+D+D+A + G+ V N PG N + EL LML AR + + G W R G
Sbjct: 82 DNVDIDAAAELGIRVCNTPGVNHHAVAELALALMLACARRLNTVLAGVDDGGWPRE--AG 139
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNII 573
+EL GK+L ++ G+ +A A GM ++
Sbjct: 140 TELRGKSLGVIGYGPSGKAIAALGVALGMRVL 171
>UniRef50_Q82XE1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=5; Proteobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Nitrosomonas
europaea
Length = 403
Score = 65.7 bits (153), Expect = 9e-10
Identities = 37/116 (31%), Positives = 61/116 (52%), Gaps = 11/116 (9%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD------ 459
+NI V+ +G+ V N PGANA + EL ML+ +R+++PA ++ D
Sbjct: 69 NNIPVNQMSARGIPVFNTPGANANAVRELVLAGMLMASRNLIPALRFVETLEGDDQSFNL 128
Query: 460 -----RALYTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCAS 612
+ ++G EL G+TL ++ L GR+VA GM ++G+DP ++ D S
Sbjct: 129 QVEAGKKQFSGLELPGRTLGVIGLGKIGRQVADIAIKLGMKVLGYDPKITIDSAWS 184
>UniRef50_A3ZW64 Cluster: Phosphoglycerate dehydrogenase, putative;
n=1; Blastopirellula marina DSM 3645|Rep:
Phosphoglycerate dehydrogenase, putative -
Blastopirellula marina DSM 3645
Length = 320
Score = 65.7 bits (153), Expect = 9e-10
Identities = 33/100 (33%), Positives = 52/100 (52%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
D+++V +A ++ + V PG S E T ++L + R+V+ + ++AG WDR G
Sbjct: 77 DSVNVPAATEQNIAVCRTPGTLHQSVVEHTIGMILAIYRNVISQNKQVRAGDWDRT--AG 134
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSA 597
GKTL I+ G+EVA GM +I +DP A
Sbjct: 135 PRAYGKTLGIIGYGVIGKEVAKAAVLLGMQVIAYDPIAPA 174
>UniRef50_A1G3C5 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Salinispora arenicola
CNS205|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Salinispora arenicola
CNS205
Length = 345
Score = 65.7 bits (153), Expect = 9e-10
Identities = 37/106 (34%), Positives = 55/106 (51%), Gaps = 2/106 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID+ +A + GV V N PG E L++++ R + + G W++ L T
Sbjct: 77 DNIDIPAASRAGVVVANNPGLGGKPVSEHALGLLIMITRDLTAVARDAMTGAWEKRLTTR 136
Query: 478 S-ELAGKTLAILALAXXGREVATRMYA-FGMNIIGFDPFVSADQCA 609
EL G TL I+ G +A R A F M ++ +DP+VSA+Q A
Sbjct: 137 RVELTGGTLGIVGCGNVGGWMARRASAGFQMRVLAYDPYVSAEQMA 182
>UniRef50_Q7WM64 Cluster: Putative dehydrogenase; n=2;
Bordetella|Rep: Putative dehydrogenase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 330
Score = 65.3 bits (152), Expect = 1e-09
Identities = 35/106 (33%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
Frame = +1
Query: 304 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG-S 480
ID+ +A + G+ V+N PGANA S EL + + L + VP A++ G W+ G
Sbjct: 81 IDLAAAERLGIPVVNTPGANARSVAELALAMAMALLKRTVPLDQAVRQGNWNIRYEAGLR 140
Query: 481 ELAGKTLAILALAXXGREVAT-RMYAFGMNIIGFDPFVSADQCASS 615
EL+G +L I+ GR +A + FGM + + P V+ A++
Sbjct: 141 ELSGMSLGIVGFGQIGRALAAMAIGGFGMRVHVYSPSVAPQDIAAA 186
>UniRef50_A4TF35 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Mycobacterium gilvum
PYR-GCK|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Mycobacterium gilvum
PYR-GCK
Length = 298
Score = 65.3 bits (152), Expect = 1e-09
Identities = 35/107 (32%), Positives = 51/107 (47%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
D++D ++A + GV V N PG + +L LAR + A++ G W + G
Sbjct: 74 DSVDHEAARRHGVTVRNTPGVFGYEVADSAFGYILNLARGYMAVDAAVRRGEWPKV--EG 131
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCASSI 618
L G L I+ GRE+A R FG ++ FDPFV A S+
Sbjct: 132 ITLDGSRLGIVGFGAIGREIAKRGAGFGQEVVAFDPFVKASPAGVSM 178
>UniRef50_A1HMI9 Cluster: Phosphoglycerate dehydrogenase; n=1;
Thermosinus carboxydivorans Nor1|Rep: Phosphoglycerate
dehydrogenase - Thermosinus carboxydivorans Nor1
Length = 326
Score = 65.3 bits (152), Expect = 1e-09
Identities = 38/97 (39%), Positives = 50/97 (51%), Gaps = 2/97 (2%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID+ +A G+ V N PG NA S ELT +++ L R + K G W +
Sbjct: 78 DNIDLAAAKTLGIPVANTPGGNATSVAELTLGMIINLYRKINILDRETKKGNWMSWEFRP 137
Query: 478 S--ELAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
S E+ GKT I+ GREVA AFG N+I +D
Sbjct: 138 SSYEVKGKTHGIIGFGNIGREVARLSQAFGTNVIYYD 174
>UniRef50_P13443 Cluster: Glycerate dehydrogenase; n=15;
Viridiplantae|Rep: Glycerate dehydrogenase - Cucumis
sativus (Cucumber)
Length = 382
Score = 65.3 bits (152), Expect = 1e-09
Identities = 38/103 (36%), Positives = 56/103 (54%), Gaps = 4/103 (3%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD---RAL 468
+N+DV++A K GV V N PG + EL +L L AR +V A ++AGR+D L
Sbjct: 98 NNVDVNAANKYGVAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMRAGRYDGWLPNL 157
Query: 469 YTGSELAGKTLAILALAXXGREVATRMY-AFGMNIIGFDPFVS 594
+ G+ L G+T+ ++ G A M F MN+I FD + S
Sbjct: 158 FVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQS 200
>UniRef50_Q65WI5 Cluster: SerA protein; n=1; Mannheimia
succiniciproducens MBEL55E|Rep: SerA protein -
Mannheimia succiniciproducens (strain MBEL55E)
Length = 326
Score = 64.9 bits (151), Expect = 2e-09
Identities = 35/99 (35%), Positives = 54/99 (54%), Gaps = 1/99 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 474
D++DV +A + G+ V+ APG+N S E LM A+ +V + ++ G + R+ Y
Sbjct: 76 DDVDVKTATELGIPVVIAPGSNTRSVAEHAFALMFACAKDIVRSDNEMRKGNFAIRSSYK 135
Query: 475 GSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFV 591
EL KTLA++ G +A A GMN+ +DPFV
Sbjct: 136 AYELNHKTLALIGYGRIGSILAQMSKAIGMNVKVYDPFV 174
>UniRef50_Q49ZM5 Cluster: Putative dehydrogenase; n=1;
Staphylococcus saprophyticus subsp. saprophyticus ATCC
15305|Rep: Putative dehydrogenase - Staphylococcus
saprophyticus subsp. saprophyticus (strain ATCC 15305
/DSM 20229)
Length = 318
Score = 64.9 bits (151), Expect = 2e-09
Identities = 35/105 (33%), Positives = 53/105 (50%), Gaps = 3/105 (2%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA---GRWDRAL 468
+N+D+D A ++ + V N P A+ S ELT L+L +AR + + W
Sbjct: 79 NNVDIDYARQQNIDVTNTPKASTNSTAELTFALVLAVARRIPEGDKLCRTTGFDGWAPLF 138
Query: 469 YTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQ 603
+ G E++GKT+ I+ L G VA R AF MNI+ P D+
Sbjct: 139 FRGREVSGKTIGIIGLGEIGSAVARRAKAFDMNILYTGPHQKVDK 183
>UniRef50_O34815 Cluster: YoaD; n=2; Bacillus|Rep: YoaD - Bacillus
subtilis
Length = 344
Score = 64.9 bits (151), Expect = 2e-09
Identities = 33/106 (31%), Positives = 54/106 (50%), Gaps = 6/106 (5%)
Frame = +1
Query: 301 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR------ 462
N+DV +A K+G+ V PG NA + E+ ++ RH ++ LK G WD
Sbjct: 94 NVDVAAASKRGIPVFYTPGRNAQAVAEMFIGNVISFLRHTSASNQWLKDGEWDSDYLQAY 153
Query: 463 ALYTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSAD 600
+ G+EL GKT+ ++ G+ +A + AF I +DP++ D
Sbjct: 154 VKFKGNELTGKTVGMIGFGAVGQRIAKLLTAFDCKIKYYDPYIQDD 199
>UniRef50_A6EBH4 Cluster: Phosphoglycerate dehydrogenase; n=1;
Pedobacter sp. BAL39|Rep: Phosphoglycerate dehydrogenase
- Pedobacter sp. BAL39
Length = 309
Score = 64.9 bits (151), Expect = 2e-09
Identities = 36/110 (32%), Positives = 58/110 (52%), Gaps = 2/110 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID A ++ + +INAP N + E LML L + A ++ G+WDR G
Sbjct: 78 DNIDEAVALERNIHLINAPEGNMDAVGEHAVGLMLSLMNNFRNADMEIRKGKWDREGNRG 137
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVS--ADQCASSIA 621
EL GKT+ I+ G +A ++ FG+ +I +D + + +DQ A ++
Sbjct: 138 YELKGKTVGIIGYGFMGSSLARKLSGFGVQVIAYDKYKTGFSDQYAREVS 187
>UniRef50_Q82U25 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=3; Nitrosomonadaceae|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Nitrosomonas
europaea
Length = 311
Score = 64.5 bits (150), Expect = 2e-09
Identities = 35/96 (36%), Positives = 51/96 (53%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+D+++A + + V N P A A + ELT LML R + +++ G W R+ G
Sbjct: 83 DNVDLEAARRLNIQVSNTPEAPAQAVAELTLGLMLDCLRQINRIDRSVRQGEWPRS--QG 140
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDP 585
LA +T+ I+ L GR VA AFG +I DP
Sbjct: 141 RLLAARTVGIVGLGHIGRRVAKLCQAFGAQVIAHDP 176
>UniRef50_A1JTE6 Cluster: Putative oxidoreductase; n=1; Yersinia
enterocolitica subsp. enterocolitica 8081|Rep: Putative
oxidoreductase - Yersinia enterocolitica serotype O:8 /
biotype 1B (strain 8081)
Length = 338
Score = 64.5 bits (150), Expect = 2e-09
Identities = 46/120 (38%), Positives = 63/120 (52%), Gaps = 22/120 (18%)
Frame = +1
Query: 301 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK-----------A 447
NIDV++A ++G+ V+ PG N+ +A ELT LML LARH+ A +ALK A
Sbjct: 79 NIDVNAATERGIPVVYTPGRNSDAAAELTIALMLNLARHIPQAHSALKQRQFTATTPGNA 138
Query: 448 GR-----WD------RALYTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVS 594
G WD ++ G EL KTL I+ G+ V AFGM ++ DP+VS
Sbjct: 139 GLKTDVVWDVTKDSPYEVFKGVELRNKTLGIVGYGSIGQRVGRIARAFGMQLLVADPYVS 198
>UniRef50_Q0W672 Cluster: Glycerate dehydrogenase; n=2; Archaea|Rep:
Glycerate dehydrogenase - Uncultured methanogenic
archaeon RC-I
Length = 319
Score = 64.5 bits (150), Expect = 2e-09
Identities = 32/95 (33%), Positives = 51/95 (53%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
D++D+D+A KGV V NAPG + + E ++L R + A ++ ++D + G
Sbjct: 77 DDVDLDAATLKGVAVANAPGYSNEAVAEHVFAMLLSFIRRISEADFWIREEKFDCTAFEG 136
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
EL GKT+ I+ G VA FGM++I +D
Sbjct: 137 RELRGKTMGIIGTGQIGLRVAEIARCFGMDVIAYD 171
>UniRef50_A0RUD3 Cluster: 2 lactate dehydrogenase; n=2;
Thermoprotei|Rep: 2 lactate dehydrogenase - Cenarchaeum
symbiosum
Length = 348
Score = 64.5 bits (150), Expect = 2e-09
Identities = 37/96 (38%), Positives = 50/96 (52%), Gaps = 4/96 (4%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL--- 468
D+IDV A +G+ V P + +LT LML L R V ++AGRW +
Sbjct: 113 DHIDVAHARGRGITVGYTPDVLTDATADLTMALMLDLLRRVTEGDRIIRAGRWRQIYGAD 172
Query: 469 -YTGSELAGKTLAILALAXXGREVATRMYAFGMNII 573
Y G+++ GKTL IL + G VA R AFGM +I
Sbjct: 173 DYLGTDVGGKTLGILGMGRIGSRVAKRAAAFGMKVI 208
>UniRef50_Q8EP33 Cluster: Glycerate dehydrogenase; n=2;
Bacillaceae|Rep: Glycerate dehydrogenase -
Oceanobacillus iheyensis
Length = 314
Score = 64.1 bits (149), Expect = 3e-09
Identities = 34/97 (35%), Positives = 50/97 (51%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID A +KG+ V N PG NA + +L LML AR++ + L+ G W+ L G
Sbjct: 81 DNIDFKYAREKGIPVTNTPGQNADAVADLAIGLMLATARNIPAKNEELRNGNWE--LSMG 138
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPF 588
E+ K L I+ G+ +A R F M ++ + F
Sbjct: 139 IEIFQKKLGIIGFGAIGQAIAQRATGFQMEVLAYGTF 175
>UniRef50_Q81N95 Cluster: D-3-phosphoglycerate dehydrogenase,
putative; n=19; Bacteria|Rep: D-3-phosphoglycerate
dehydrogenase, putative - Bacillus anthracis
Length = 390
Score = 64.1 bits (149), Expect = 3e-09
Identities = 34/110 (30%), Positives = 60/110 (54%), Gaps = 9/110 (8%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD------ 459
+NI V+ +KG+ V N PGANA + EL +++ +R+++ + K +
Sbjct: 62 NNIPVERCTEKGIVVFNTPGANANAVKELIIASLIMSSRNIINGVSWTKNLEGEEVPQLV 121
Query: 460 ---RALYTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSAD 600
+ + GSE+AGK L ++ L G VA A GM+++G+DP++S +
Sbjct: 122 ESGKKQFVGSEIAGKRLGVIGLGAIGALVANDALALGMDVVGYDPYISVE 171
>UniRef50_A4S3N1 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 380
Score = 64.1 bits (149), Expect = 3e-09
Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 1/109 (0%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+D + A ++G+ V+ P + LS E +M+ L RH+ + L+ G + G
Sbjct: 114 DNVDCERARERGISVLRVPAYDPLSISEHAVAMMMSLNRHLCASRDRLRMGNFTLDGLVG 173
Query: 478 SELAGKTLAILALAXXGREVATRM-YAFGMNIIGFDPFVSADQCASSIA 621
S + GKT+ ++ GR VA + F M ++G+D F D C ++
Sbjct: 174 SSMRGKTVGVVGTGKIGRGVAEILKNGFQMRVLGYDKFEKDDFCGDYVS 222
>UniRef50_Q5FUW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=55;
Bacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 416
Score = 63.3 bits (147), Expect = 5e-09
Identities = 31/95 (32%), Positives = 51/95 (53%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
+ +D+++A G+ V NAP +N S EL +++L R + S A G WD++
Sbjct: 88 NQVDLNAARMLGIPVFNAPFSNTRSVAELVMGEIVMLLRRIPSRSEACHKGGWDKSATNA 147
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
E+ GKTL I+ G +++ AFGM ++ FD
Sbjct: 148 WEVRGKTLGIVGYGSIGSQLSVLAEAFGMRVLYFD 182
>UniRef50_Q04DF1 Cluster: Lactate dehydrogenase related enzyme; n=1;
Oenococcus oeni PSU-1|Rep: Lactate dehydrogenase related
enzyme - Oenococcus oeni (strain BAA-331 / PSU-1)
Length = 311
Score = 63.3 bits (147), Expect = 5e-09
Identities = 34/99 (34%), Positives = 56/99 (56%), Gaps = 1/99 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL-YT 474
DN+D AG+ GV V P ANA + E T +L L++++ S ++ G + L +
Sbjct: 74 DNVDEKFAGEHGVYVTITPMANASTVAETTIAEILDLSKNLTKISDEMRQGNFAYKLDHM 133
Query: 475 GSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFV 591
G +L+ K + ++ GR+VA + A GM+++ FDPFV
Sbjct: 134 GFDLSHKKIGVMGYGRIGRQVAEKANALGMDVLIFDPFV 172
>UniRef50_A4EAR0 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 387
Score = 63.3 bits (147), Expect = 5e-09
Identities = 35/111 (31%), Positives = 59/111 (53%), Gaps = 10/111 (9%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD------ 459
+NI V+ KKGV V N+PGAN+ + EL ++++ +R VV + ++ D
Sbjct: 61 NNIPVEEYAKKGVVVFNSPGANSNAVKELVLGMLVLSSRGVVQSMNWVRDNADDPEIQVD 120
Query: 460 ----RALYTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSAD 600
+ + G EL GK + ++ L G +VA GM++ G+DPF+S +
Sbjct: 121 AEKAKKAFVGRELKGKRIGVIGLGNVGSKVANACVDLGMDVYGYDPFISVE 171
>UniRef50_A1HM37 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; cellular organisms|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Thermosinus carboxydivorans Nor1
Length = 365
Score = 63.3 bits (147), Expect = 5e-09
Identities = 33/104 (31%), Positives = 54/104 (51%), Gaps = 3/104 (2%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
+N++V A K+G+ V N G NA + + T LML R++ A ++K G W +
Sbjct: 107 ENVNVKEATKRGILVFNIEGRNAEAVSDFTVGLMLAECRNIARAHYSIKNGGWRKEFSNS 166
Query: 478 S---ELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSAD 600
EL GK + ++ GR VA ++ FG+ + +DPFV +
Sbjct: 167 DWVPELKGKKVGLVGFGYIGRLVAQKLSGFGVTRLVYDPFVDEE 210
>UniRef50_Q986P2 Cluster: Phosphoglycerate dehydrogenase; n=14;
cellular organisms|Rep: Phosphoglycerate dehydrogenase -
Rhizobium loti (Mesorhizobium loti)
Length = 330
Score = 62.9 bits (146), Expect = 6e-09
Identities = 34/101 (33%), Positives = 52/101 (51%), Gaps = 4/101 (3%)
Frame = +1
Query: 301 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY--- 471
NID+ +A G+ V+N PG NA + E T +L R + AL+ G W LY
Sbjct: 90 NIDMAAARAHGITVVNVPGRNATAVAEFTLGAILAETRLIRVGHEALRKGEWRGDLYRAD 149
Query: 472 -TGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFV 591
TG EL+ T+ ++ G +V + AFG +++ DP+V
Sbjct: 150 RTGRELSEMTVGVIGYGNIGTKVVRLLRAFGCHVLVSDPYV 190
>UniRef50_Q8R8Q2 Cluster: Lactate dehydrogenase and related
dehydrogenases; n=8; cellular organisms|Rep: Lactate
dehydrogenase and related dehydrogenases -
Thermoanaerobacter tengcongensis
Length = 358
Score = 62.9 bits (146), Expect = 6e-09
Identities = 39/105 (37%), Positives = 56/105 (53%), Gaps = 3/105 (2%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSA-CELTCTLMLVLARHVVPASTALKAGRW-DRALY 471
D ID++SA KKG V G A E L+L + R V AS +K G+W +RA +
Sbjct: 106 DAIDIESATKKGTIVTIVEGIVEREAVAENAVALLLDVMRKVREASIKVKEGKWHERANF 165
Query: 472 TGSELAGKTLAILALAXXGREVATRM-YAFGMNIIGFDPFVSADQ 603
G E+ GKT I+ + G VA + Y FG +I +DP +S ++
Sbjct: 166 IGYEIKGKTAGIIGIGNIGSRVAEILKYGFGAEVIAYDPNLSKEE 210
>UniRef50_Q88YI0 Cluster: Phosphoglycerate dehydrogenase; n=5;
Bacilli|Rep: Phosphoglycerate dehydrogenase -
Lactobacillus plantarum
Length = 324
Score = 62.9 bits (146), Expect = 6e-09
Identities = 33/95 (34%), Positives = 51/95 (53%), Gaps = 3/95 (3%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRAL 468
+NID+ +A K+ + V N P +A++ E T L++ LA +V ++ W
Sbjct: 79 NNIDIAAAAKRQIPVTNTPNVSAVATAESTVGLIISLAHRIVEGDHLMRTSGFNGWAPLF 138
Query: 469 YTGSELAGKTLAILALAXXGREVATRMYAFGMNII 573
+ G L GKTL IL L G+ VA R++AF M I+
Sbjct: 139 FLGHNLQGKTLGILGLGQIGQAVAKRLHAFDMPIL 173
>UniRef50_Q72KT6 Cluster: Glycerate dehydrogenase/glyoxylate
reductase; n=2; Thermus thermophilus|Rep: Glycerate
dehydrogenase/glyoxylate reductase - Thermus
thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 338
Score = 62.9 bits (146), Expect = 6e-09
Identities = 31/95 (32%), Positives = 53/95 (55%), Gaps = 3/95 (3%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG---RWDRAL 468
D++D+++A ++G+ V + PG + +LT L+L +AR VV + + G W L
Sbjct: 104 DHVDLEAARERGIRVTHTPGVLTEATADLTLALLLAVARRVVEGAAYARDGLWRAWHPEL 163
Query: 469 YTGSELAGKTLAILALAXXGREVATRMYAFGMNII 573
G +L G TL ++ + G+ VA R AFGM ++
Sbjct: 164 LLGLDLQGLTLGLVGMGRIGQAVAKRALAFGMRVV 198
>UniRef50_A6PPS4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Victivallis vadensis
ATCC BAA-548|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Victivallis vadensis ATCC
BAA-548
Length = 316
Score = 62.9 bits (146), Expect = 6e-09
Identities = 39/114 (34%), Positives = 53/114 (46%), Gaps = 2/114 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNI++ A +KG+ N PGA S E ++L+ AR + A+ + G W TG
Sbjct: 77 DNINLPRAAEKGIYCTNTPGALEQSVAECAIGMILLAARQFIAAADDCRNGLWQP--QTG 134
Query: 478 SELAGKTLAILALAXXGREVAT-RMYAFGMNIIGFDPFVSADQC-ASSIAPRWS 633
ELAGKTLA++ G VA FGM++ G C A WS
Sbjct: 135 CELAGKTLAVIGCGAIGSRVAAIAKNGFGMSVTGVIRSAPRPDCPADRFVKNWS 188
>UniRef50_Q6MY49 Cluster: NAD-dependant D-isomer specific
2-hydroxyacid dehydrogenase, putative; n=5;
Eurotiomycetidae|Rep: NAD-dependant D-isomer specific
2-hydroxyacid dehydrogenase, putative - Aspergillus
fumigatus (Sartorya fumigata)
Length = 335
Score = 62.9 bits (146), Expect = 6e-09
Identities = 33/91 (36%), Positives = 48/91 (52%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID+ + +KG+ V + P A + ++ LM+ R +AL+AG+W G
Sbjct: 88 DNIDIPACSEKGIAVSSTPVAVNHATADVGIFLMIGALRQAYIPLSALRAGQWQGKTTLG 147
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNI 570
+ GK L IL + GRE+A R AFGM I
Sbjct: 148 HDPQGKVLGILGMGGIGREMANRARAFGMKI 178
>UniRef50_Q1WVK4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Lactobacillus salivarius subsp. salivarius UCC118|Rep:
D-3-phosphoglycerate dehydrogenase - Lactobacillus
salivarius subsp. salivarius (strain UCC118)
Length = 394
Score = 62.5 bits (145), Expect = 8e-09
Identities = 38/111 (34%), Positives = 58/111 (52%), Gaps = 9/111 (8%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA-STALKAGRWDRALYT 474
+NI ++ A +G V N PG+NA + EL T++L+ R V + A K D +L T
Sbjct: 61 NNIPLEKATSQGTAVFNTPGSNANAVKELIITMLLLSVRPVFASVKWAQKLAGADVSLQT 120
Query: 475 --------GSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQ 603
G+EL GK + I+ L G VA GM +IG+DP++S ++
Sbjct: 121 EKGKNHFAGTELYGKKIGIIGLGNIGSRVAKACMDLGMKVIGYDPYISVEK 171
>UniRef50_O58320 Cluster: Glyoxylate reductase; n=16; cellular
organisms|Rep: Glyoxylate reductase - Pyrococcus
horikoshii
Length = 334
Score = 62.5 bits (145), Expect = 8e-09
Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 7/99 (7%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR----- 462
DNID++ A K+G+ V N P + +L L+L ARHVV +++G W +
Sbjct: 79 DNIDIEEATKRGIYVTNTPDVLTDATADLAFALLLATARHVVKGDRFVRSGEWKKRGVAW 138
Query: 463 --ALYTGSELAGKTLAILALAXXGREVATRMYAFGMNII 573
+ G ++ GKT+ I+ L G+ +A R F M I+
Sbjct: 139 HPKWFLGYDVYGKTIGIIGLGRIGQAIAKRAKGFNMRIL 177
>UniRef50_Q83AZ4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=11; Bacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Coxiella burnetii
Length = 388
Score = 62.1 bits (144), Expect = 1e-08
Identities = 43/122 (35%), Positives = 61/122 (50%), Gaps = 14/122 (11%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA-----------STALK 444
+NI V GV V+N PGANA + EL T +L+ +RH+ PA T
Sbjct: 63 NNIPVRPLTLSGVPVLNTPGANANAVKELVITGILLASRHIYPALDYARHIEGDDETITH 122
Query: 445 AGRWDRALYTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFV---SADQCASS 615
++ ++G EL GKTL I+ L G +VA GM IG+DP + SA + +S
Sbjct: 123 QVEKNKKRFSGFELPGKTLGIIGLGQIGVKVANAAIRLGMKAIGYDPAITVRSAWELSSE 182
Query: 616 IA 621
+A
Sbjct: 183 VA 184
>UniRef50_Q6F7L0 Cluster: Glycerate dehydrogenase; n=3;
Gammaproteobacteria|Rep: Glycerate dehydrogenase -
Acinetobacter sp. (strain ADP1)
Length = 318
Score = 62.1 bits (144), Expect = 1e-08
Identities = 37/98 (37%), Positives = 52/98 (53%), Gaps = 6/98 (6%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL--- 468
+N+D+ +A +G+ V N G S + T TLML LA ++ A+ GRW +A
Sbjct: 78 NNVDLRAAKAQGIVVCNCQGYGTASVAQHTLTLMLALATSLLRYDHAVAQGRWQQASQFC 137
Query: 469 ---YTGSELAGKTLAILALAXXGREVATRMYAFGMNII 573
Y EL+GKTL I+ G+EVA AFGM I+
Sbjct: 138 FLDYPIIELSGKTLGIVGYGELGKEVARLAQAFGMKIL 175
>UniRef50_Q6A5K9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, putative D-3- phosphoglycerate
dehydrogenase; n=1; Propionibacterium acnes|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase, putative
D-3- phosphoglycerate dehydrogenase - Propionibacterium
acnes
Length = 321
Score = 62.1 bits (144), Expect = 1e-08
Identities = 36/95 (37%), Positives = 52/95 (54%), Gaps = 3/95 (3%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRAL 468
+NID+D+A + GV V + PG + +L TL+L + R A ++AGR +D
Sbjct: 76 NNIDLDAAKQAGVVVTSTPGVLHEATADLAFTLLLEVTRRTGEAERWVRAGRAWRYDHTF 135
Query: 469 YTGSELAGKTLAILALAXXGREVATRMYAFGMNII 573
G+ L G TL I+ L G +A R AFGMN+I
Sbjct: 136 MLGAGLQGATLGIVGLGQIGEAMARRGAAFGMNVI 170
>UniRef50_Q11JH0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Mesorhizobium sp.
BNC1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Mesorhizobium sp. (strain BNC1)
Length = 342
Score = 62.1 bits (144), Expect = 1e-08
Identities = 37/102 (36%), Positives = 55/102 (53%), Gaps = 5/102 (4%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
D ID++ A ++GV V G+NA + E T L+L R + A +++ G+W +YT
Sbjct: 84 DKIDLEGAERQGVYVAITAGSNAGAVAEHTIMLILAALRRLALADQSMREGKW---IYTE 140
Query: 478 -----SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPF 588
+L+GKT+ IL GR VA R+ F + II DPF
Sbjct: 141 LRPLCRKLSGKTVGILGFGNIGRNVAQRLQGFDVEIIYHDPF 182
>UniRef50_A3PPC6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Rhodobacteraceae|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Rhodobacter sphaeroides (strain ATCC 17029
/ ATH 2.4.9)
Length = 331
Score = 62.1 bits (144), Expect = 1e-08
Identities = 38/100 (38%), Positives = 52/100 (52%), Gaps = 2/100 (2%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 474
D +D ++A +KGV V N PGANA S EL L L +AR + A AL+ G+ R
Sbjct: 74 DPVDKEAAARKGVVVANTPGANARSVAELAVGLALAVARRIPAADRALREGKTGFRESAR 133
Query: 475 GSELAGKTLAILALAXXGREVATRM-YAFGMNIIGFDPFV 591
SEL G+T ++ GRE + AF M ++ P V
Sbjct: 134 FSELRGRTALVVGWGASGRETGRMLAQAFDMRLLVHSPRV 173
>UniRef50_A1W7V5 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Acidovorax sp. (strain JS42)
Length = 337
Score = 62.1 bits (144), Expect = 1e-08
Identities = 33/100 (33%), Positives = 48/100 (48%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
D+ID+D G+ V N P + E L+L ++RH+V + + G + + G
Sbjct: 76 DHIDLDYCRAHGIAVSNVPDYGDATVAEHAFALLLAVSRHIVTGAERTRRGDFSQHGLRG 135
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSA 597
EL GKTL +L GR V FGM I+ +D F A
Sbjct: 136 FELRGKTLGVLGTGRIGRRVIEIGKGFGMKIVAYDLFPDA 175
>UniRef50_Q6L245 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Thermoplasmatales|Rep: D-3-phosphoglycerate
dehydrogenase - Picrophilus torridus
Length = 299
Score = 62.1 bits (144), Expect = 1e-08
Identities = 32/97 (32%), Positives = 50/97 (51%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
D+IDVD A +KG+ ++ APG++ S ELT ++ AR ++ + D G
Sbjct: 76 DSIDVDYAQEKGIKIVYAPGSSTESVVELTVAFAVIAARQIIKGVENTRKN--DFTKLKG 133
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPF 588
EL+GKTL I+ GR +A F + I +D +
Sbjct: 134 IELSGKTLGIIGYGRIGRAIANAFSVFNVRSIAYDAY 170
Score = 35.1 bits (77), Expect = 1.4
Identities = 18/59 (30%), Positives = 34/59 (57%)
Frame = +2
Query: 83 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDEA 259
+LI D V E L+ I+++ELL +I ++D ++VRS T++ ++++D A
Sbjct: 5 ILICDPVDGIMIEKLSK-DFDIDNSPDITRDELLKKIGDYDIIIVRSRTKIDRDIIDNA 62
>UniRef50_Q3Y1E6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Enterococcus faecium DO|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Enterococcus faecium DO
Length = 386
Score = 61.7 bits (143), Expect = 1e-08
Identities = 34/103 (33%), Positives = 55/103 (53%), Gaps = 9/103 (8%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS---------TALKAG 450
+ I+V+ A + G V+N PG NA + EL +L+ +R ++ AS L+
Sbjct: 61 NTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPIIEASRMVQTLTGPNILEQA 120
Query: 451 RWDRALYTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGF 579
R+ Y G EL GKT+ +L L G +VA Y+ GM+++G+
Sbjct: 121 ENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDVLGY 163
>UniRef50_Q1MQK2 Cluster: Phosphoglycerate dehydrogenase and related
dehydrogenases; n=1; Lawsonia intracellularis
PHE/MN1-00|Rep: Phosphoglycerate dehydrogenase and
related dehydrogenases - Lawsonia intracellularis
(strain PHE/MN1-00)
Length = 302
Score = 61.7 bits (143), Expect = 1e-08
Identities = 34/98 (34%), Positives = 54/98 (55%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNIDV+ A +K + + N P A++ E T L+L L R + +++G W + + G
Sbjct: 81 DNIDVEYAQEKNIIIYNPPKGYAIAVAEFTVGLILSLIRQIPYQDKEVRSGVWHKRI--G 138
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFV 591
+ L GK + I+ L G+ VA R+ FG++I DP V
Sbjct: 139 NLLHGKRVGIIGLGQVGKAVAERLLPFGVDIAYNDPNV 176
>UniRef50_Q8CPW2 Cluster: Glycerate dehydrogenase; n=4;
Staphylococcus|Rep: Glycerate dehydrogenase -
Staphylococcus epidermidis (strain ATCC 12228)
Length = 323
Score = 61.3 bits (142), Expect = 2e-08
Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 3/95 (3%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR---AL 468
DNID+ A K GV V N P + EL TLML +AR ++ A++ ++ G+W L
Sbjct: 79 DNIDISLAKKHGVVVTNTPHVLTETTAELGFTLMLTVARRIIEATSYIQEGKWKSWGPYL 138
Query: 469 YTGSELAGKTLAILALAXXGREVATRMYAFGMNII 573
+G ++ G T+ I + G+ A R+ F II
Sbjct: 139 LSGKDVYGATVGIFGMGDIGKAFARRLQGFDARII 173
>UniRef50_Q89QF5 Cluster: Blr3173 protein; n=3; Bradyrhizobium|Rep:
Blr3173 protein - Bradyrhizobium japonicum
Length = 360
Score = 60.9 bits (141), Expect = 3e-08
Identities = 33/106 (31%), Positives = 57/106 (53%), Gaps = 2/106 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR-WDRALYT 474
D +DV++ GV V+N G NA S E +ML L++ ++ + L+ R +R
Sbjct: 101 DPVDVEACTDAGVLVVNQSGGNAHSVAEHALAMMLTLSKRIIQSDRRLRRERDVNRNDLV 160
Query: 475 GSELAGKTLAILALAXXGREVATRMYA-FGMNIIGFDPFVSADQCA 609
G+E+ KT+ I+ L GR +A GM ++ +DP+++A+ A
Sbjct: 161 GNEVEHKTVGIIGLGNVGRRIAALCNGLLGMKVLAYDPYLTAEVMA 206
>UniRef50_Q2S4U0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding domain protein; n=2; cellular
organisms|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding domain protein - Salinibacter
ruber (strain DSM 13855)
Length = 321
Score = 60.9 bits (141), Expect = 3e-08
Identities = 34/95 (35%), Positives = 48/95 (50%), Gaps = 3/95 (3%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG---RWDRAL 468
DNID+++A V V + PG + + L+L ARHV A ++ G RW+
Sbjct: 80 DNIDLEAAEAHDVAVTHTPGVLTDATADQAWALLLAAARHVPAADRYVRDGRFERWETTH 139
Query: 469 YTGSELAGKTLAILALAXXGREVATRMYAFGMNII 573
G ELA KT+ I+ + G VA R FGM +I
Sbjct: 140 LMGMELARKTIGIVGMGRIGTAVARRALGFGMEVI 174
>UniRef50_A6C853 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: D-3-phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 328
Score = 60.9 bits (141), Expect = 3e-08
Identities = 31/97 (31%), Positives = 51/97 (52%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
D +D+ +A + + V PG N S E L++ +AR A+++G W+R L
Sbjct: 82 DAVDLAAADAQNIVVTITPGVNHHSVAEQAFALLMGIARMTRTQDRAVRSGEWERELTP- 140
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPF 588
+ G T+ I+ L G+ VATR GM+++ +DPF
Sbjct: 141 -RVWGSTIGIVGLGRIGQAVATRAIGMGMHVLAYDPF 176
>UniRef50_A0ZEB8 Cluster: Predicted dehydrogenase; n=6;
Cyanobacteria|Rep: Predicted dehydrogenase - Nodularia
spumigena CCY 9414
Length = 341
Score = 60.9 bits (141), Expect = 3e-08
Identities = 36/104 (34%), Positives = 55/104 (52%), Gaps = 2/104 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DRALYT 474
D ID+ A K GV V+N PG + + E T ++L LA+ + + +K G + R
Sbjct: 90 DAIDISVATKHGVVVVNNPGLSTTAVAEHTICMILALAKKLTFLNQCVKTGNYLIRNQVQ 149
Query: 475 GSELAGKTLAILALAXXGREVATR-MYAFGMNIIGFDPFVSADQ 603
+L GKTL I+ L G VA++ AF M ++ +DP+V Q
Sbjct: 150 PMQLEGKTLGIVGLGRIGSAVASKCSAAFQMRVLAYDPYVLPSQ 193
>UniRef50_Q27SS3 Cluster: Glycerate dehydrogenase-like protein; n=2;
Eukaryota|Rep: Glycerate dehydrogenase-like protein -
Trimastix pyriformis
Length = 232
Score = 60.9 bits (141), Expect = 3e-08
Identities = 36/95 (37%), Positives = 51/95 (53%), Gaps = 3/95 (3%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG---RWDRAL 468
+NID+ +A ++ V V N P A + +LT L+L +AR +V ++AG W
Sbjct: 78 NNIDLTAANERHVVVTNTPHCLAEATADLTMGLLLAVARRLVEGDGLVRAGLFKGWAPEF 137
Query: 469 YTGSELAGKTLAILALAXXGREVATRMYAFGMNII 573
G +L GKTL I+ L G VA R AFGM I+
Sbjct: 138 LLGMDLHGKTLGIIGLGEIGTCVARRARAFGMRIV 172
>UniRef50_UPI000023F60F Cluster: hypothetical protein FG08018.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG08018.1 - Gibberella zeae PH-1
Length = 901
Score = 60.5 bits (140), Expect = 3e-08
Identities = 37/103 (35%), Positives = 51/103 (49%), Gaps = 2/103 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG-RWDRALYT 474
D IDVD+ +G+ + N PG NA + EL TL AR V +G + +
Sbjct: 90 DKIDVDACASRGIKIFNTPGVNARAVAELVLTLATASARQVGSIIAKQSSGILVPKEKCS 149
Query: 475 GSELAGKTLAILALAXXGREVATRMY-AFGMNIIGFDPFVSAD 600
G L KT+ IL + G+ VA AF N+I +DPF+ AD
Sbjct: 150 GLILHEKTIGILGMGNIGKCVAKIFRGAFDANVIAYDPFLPAD 192
>UniRef50_Q7X388 Cluster: Phosphoglycerate dehydrogenase; n=3;
Escherichia coli|Rep: Phosphoglycerate dehydrogenase -
Escherichia coli
Length = 306
Score = 60.5 bits (140), Expect = 3e-08
Identities = 37/107 (34%), Positives = 54/107 (50%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNIDVD A K + V A AN++S E+T +ML +R V + + G+ R + G
Sbjct: 82 DNIDVDYANSKDIVVHKALNANSISVAEMTILMMLSSSRKYVEIESQARNGKDIRLV--G 139
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCASSI 618
EL K L ++ L G+ VA ++ GM I DP + + S I
Sbjct: 140 YELYQKNLGLIGLGAIGQHVAHIAHSMGMTITAHDPHIDKSKVPSYI 186
>UniRef50_Q44NM9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Chlorobium limicola DSM 245|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Chlorobium limicola DSM 245
Length = 305
Score = 60.5 bits (140), Expect = 3e-08
Identities = 31/95 (32%), Positives = 51/95 (53%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
D++D+D A +KG+ V N P S ELT + L L R V A +K G W + + G
Sbjct: 82 DSVDLDYAKQKGIVVTNTPDGPTRSVAELTIAMTLALLRKVPQAHMNIKQGVWKKEI--G 139
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
+ + K + ++ L G+ A++ AFG +++ FD
Sbjct: 140 NLMYEKKVGLIGLGKIGKLAASQFQAFGCSVMAFD 174
>UniRef50_A6LZ51 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Clostridium
beijerinckii NCIMB 8052|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Clostridium
beijerinckii NCIMB 8052
Length = 320
Score = 60.5 bits (140), Expect = 3e-08
Identities = 35/104 (33%), Positives = 56/104 (53%), Gaps = 3/104 (2%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL-YT 474
DN+D+D+ + G+ NA G NA + E L+L +++ + +K + L YT
Sbjct: 80 DNVDIDACTQYGIWAANAAGVNAQAVAEHVMALILSYYKNIPFLDSFIKNKIDENELQYT 139
Query: 475 GSELAGKTLAILALAXXGREVATRMYAFGMNIIGF--DPFVSAD 600
GSEL GKT+ I+ G++VA F MNI+ + +P V +D
Sbjct: 140 GSELKGKTIGIIGFGAVGKKVAEFCRVFDMNILVYARNPVVQSD 183
>UniRef50_A4EQ78 Cluster: Dehydrogenase; n=1; Roseobacter sp.
SK209-2-6|Rep: Dehydrogenase - Roseobacter sp. SK209-2-6
Length = 343
Score = 60.5 bits (140), Expect = 3e-08
Identities = 33/105 (31%), Positives = 53/105 (50%), Gaps = 1/105 (0%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 474
D +DV++A KG+ V N + L L LAR + A AG W ++
Sbjct: 90 DIVDVNAATAKGILVTNVQNYCTEEVADHAIALWLALARKLPDYDRATHAGLWQWQSGQP 149
Query: 475 GSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCA 609
L G+T+ +++L G+ +A R AFG+N+I +DPF+ + A
Sbjct: 150 VHRLRGRTMGVVSLGKIGQAIAARARAFGVNVIAYDPFLPGEAAA 194
>UniRef50_A3JX80 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding protein; n=1; Sagittula
stellata E-37|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding protein - Sagittula stellata
E-37
Length = 320
Score = 60.5 bits (140), Expect = 3e-08
Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 1/99 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 474
D +DV + +G+ + AN+ S E C L+L + + A A++ G W R
Sbjct: 76 DAVDVAALNARGIALAVCGDANSTSVAEHACMLILAAFKRALRADVAVRRGPWGWRNQLE 135
Query: 475 GSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFV 591
++ G+ L IL G+ AT M FGMNI DP++
Sbjct: 136 SQDIRGRNLLILGFGRIGQHTATMMSGFGMNIRAHDPYL 174
>UniRef50_A4RX85 Cluster: Predicted protein; n=3; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 454
Score = 60.1 bits (139), Expect = 4e-08
Identities = 38/117 (32%), Positives = 58/117 (49%), Gaps = 16/117 (13%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELT-CTLMLVLA------RHVVPASTALKAGRW 456
+NI V + G+ V N PGANA + EL C+L+L +HV + G +
Sbjct: 93 NNIPVKEMSELGIPVFNTPGANANAVKELVVCSLLLASRGIIEGNKHVNDVINVEENGDY 152
Query: 457 ---------DRALYTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSAD 600
D+A++ G+E+ GKTL ++ L G V GMN+IG+DP +S +
Sbjct: 153 AKISVRIEKDKAMFGGTEIEGKTLGVIGLGAIGSRVVNAALGLGMNVIGYDPVLSLE 209
>UniRef50_Q1K3M3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Desulfuromonas acetoxidans DSM 684|Rep:
D-3-phosphoglycerate dehydrogenase - Desulfuromonas
acetoxidans DSM 684
Length = 528
Score = 59.7 bits (138), Expect = 6e-08
Identities = 29/101 (28%), Positives = 52/101 (51%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
+NI +D+A KG+ V N P + + E +M+ LAR + A ++ G+W + G
Sbjct: 76 ENIAMDAANIKGIVVTNTPLGSTTTIAEHAIAMMMSLARLIPQAHESMSQGKWQSTEFLG 135
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSAD 600
S++ KTL ++ GR V M++ +DP++S +
Sbjct: 136 SDINDKTLGVIGGGKIGRRVIEYARGLHMHVNLYDPYLSEE 176
Score = 35.1 bits (77), Expect = 1.4
Identities = 21/57 (36%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Frame = +2
Query: 83 VLIVDGVGAKCAELLN-AYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 250
VLI D + +L + A GI + I+ + LL I N+DAL+VR T V++E++
Sbjct: 3 VLISDNFSSAGLKLFDEAEGITADYQPGITHDNLLKIINNYDALIVRGGTTVSEELI 59
>UniRef50_Q03WU1 Cluster: Lactate dehydrogenase related
dehydrogenase; n=1; Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293|Rep: Lactate dehydrogenase
related dehydrogenase - Leuconostoc mesenteroides subsp.
mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 312
Score = 59.7 bits (138), Expect = 6e-08
Identities = 32/94 (34%), Positives = 52/94 (55%), Gaps = 2/94 (2%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR--WDRALY 471
DNI V+SA K GV V N PGANA++ EL TL+L + R V A+ +++ G A
Sbjct: 77 DNIPVESATKHGVWVTNTPGANAIAVAELAVTLILTVLRKVNQATNSVQKGEALTYPASL 136
Query: 472 TGSELAGKTLAILALAXXGREVATRMYAFGMNII 573
G L+GK + ++ + + ++ FG +++
Sbjct: 137 MGHNLSGKIIGLIGYGQIAQNLEKILHGFGAHVL 170
>UniRef50_A6GGA6 Cluster: Probable 2-hydroxyacid dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: Probable 2-hydroxyacid
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 327
Score = 59.7 bits (138), Expect = 6e-08
Identities = 34/95 (35%), Positives = 49/95 (51%), Gaps = 3/95 (3%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR---AL 468
DN+DV + + + V N PG + +L L+L AR++ AS + GRW
Sbjct: 85 DNVDVPACTARSIRVGNTPGVLTDATADLAMALLLSAARNLPAASLDAREGRWQTWSPTG 144
Query: 469 YTGSELAGKTLAILALAXXGREVATRMYAFGMNII 573
+ G EL G TL ++ L G VA R AFGM+I+
Sbjct: 145 WLGLELRGATLGVVGLGKIGLAVAQRARAFGMDIL 179
>UniRef50_A7P8C8 Cluster: Chromosome chr3 scaffold_8, whole genome
shotgun sequence; n=3; core eudicotyledons|Rep:
Chromosome chr3 scaffold_8, whole genome shotgun
sequence - Vitis vinifera (Grape)
Length = 418
Score = 59.7 bits (138), Expect = 6e-08
Identities = 34/99 (34%), Positives = 53/99 (53%), Gaps = 4/99 (4%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD---RAL 468
+N+DV++A K GV V N PG + EL +L + AR +V A ++AG +D L
Sbjct: 98 NNVDVNAANKYGVAVGNTPGVLTETTAELAASLSMAAARRIVEADEFMRAGLYDGWLPHL 157
Query: 469 YTGSELAGKTLAILALAXXGREVATRMY-AFGMNIIGFD 582
+ G+ L G+T+ ++ G A M F MN+I +D
Sbjct: 158 FVGNLLRGQTVGVIGAGRIGSAYARMMVEGFKMNLIYYD 196
>UniRef50_A2SRM1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Methanocorpusculum
labreanum Z|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Methanocorpusculum
labreanum (strain ATCC 43576 / DSM 4855 / Z)
Length = 334
Score = 59.7 bits (138), Expect = 6e-08
Identities = 31/91 (34%), Positives = 50/91 (54%), Gaps = 1/91 (1%)
Frame = +1
Query: 304 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSE 483
+DV +A K + V N P AN+L+ E T L+L L + + + K+G W + Y +
Sbjct: 93 VDVPAAKKHNIAVTNVPHANSLAVSEFTVALILTLMKKIPIMNKETKSGLWHK--YISQD 150
Query: 484 LAGKTLAILALAXXGREVATRM-YAFGMNII 573
++ KT+ I+ + GR VA +M Y FG I+
Sbjct: 151 VSDKTIGIVGMGSIGRLVAKKMYYGFGCKIL 181
>UniRef50_P40054 Cluster: D-3-phosphoglycerate dehydrogenase 1;
n=35; Eukaryota|Rep: D-3-phosphoglycerate dehydrogenase
1 - Saccharomyces cerevisiae (Baker's yeast)
Length = 469
Score = 59.7 bits (138), Expect = 6e-08
Identities = 28/95 (29%), Positives = 51/95 (53%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
+ +D+D A +G+ V N+P +N+ S EL ++ LAR + S L G W++
Sbjct: 134 NQVDLDYATSRGIAVFNSPFSNSRSVAELVIAEIISLARQLGDRSIELHTGTWNKVAARC 193
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
E+ GKTL I+ G +++ A G++++ +D
Sbjct: 194 WEVRGKTLGIIGYGHIGSQLSVLAEAMGLHVLYYD 228
>UniRef50_UPI00015BD3AA Cluster: UPI00015BD3AA related cluster; n=1;
unknown|Rep: UPI00015BD3AA UniRef100 entry - unknown
Length = 332
Score = 59.3 bits (137), Expect = 8e-08
Identities = 33/95 (34%), Positives = 46/95 (48%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
D+IDV A KG+ V N P S E LML LAR + ++ G + + G
Sbjct: 77 DHIDVAYANSKGITVCNVPSYGEESVSEYAIMLMLALARKLRETIDNVEKGVYKTSNLRG 136
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
ELAGKTL ++ G A FGM+++ +D
Sbjct: 137 IELAGKTLGVIGTGRIGARTALLARCFGMDVVCYD 171
>UniRef50_Q7UQC8 Cluster: Probable 2-hydroxyacid dehydrogenase; n=1;
Pirellula sp.|Rep: Probable 2-hydroxyacid dehydrogenase
- Rhodopirellula baltica
Length = 406
Score = 59.3 bits (137), Expect = 8e-08
Identities = 32/96 (33%), Positives = 53/96 (55%), Gaps = 4/96 (4%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRAL 468
+NIDVD+A +GV V N P + +L +L+ +RHV+PA ++ G W+
Sbjct: 165 NNIDVDAAKTRGVVVGNTPDVLTDATADLAVSLLFAASRHVLPAGNQVREGEWKTWEPTG 224
Query: 469 YTGSELAGKTLAILALAXXGREVATRMY-AFGMNII 573
+ G E + KTL I+ + G+ A R+ +GMN++
Sbjct: 225 WLGVEPSDKTLGIVGMGRIGKATAKRLVGGWGMNLL 260
>UniRef50_Q11UL6 Cluster: Phosphoglycerate dehydrogenase; n=1;
Cytophaga hutchinsonii ATCC 33406|Rep: Phosphoglycerate
dehydrogenase - Cytophaga hutchinsonii (strain ATCC
33406 / NCIMB 9469)
Length = 314
Score = 59.3 bits (137), Expect = 8e-08
Identities = 31/106 (29%), Positives = 53/106 (50%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID + +K + + +A N ++ E T L+L L ++V + T +K W R G
Sbjct: 78 DNIDKEYLKEKNIALFHASEGNRVAVGEHTLGLILALINNIVRSDTEVKDAIWLREENRG 137
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCASS 615
EL T+ ++ G+E + R+ AFG II +D + C ++
Sbjct: 138 YELESLTVGLIGYGNMGKETSKRLAAFGCKIIAYDKYRENYSCKNA 183
Score = 39.1 bits (87), Expect = 0.088
Identities = 21/56 (37%), Positives = 32/56 (57%)
Frame = +2
Query: 86 LIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 253
LIVD V +LL+ IA K SKE + +P ++ LV+RS +V K+++D
Sbjct: 7 LIVDDVDTALFQLLDKAAIAYDYKPDWSKETCIEALPAYEGLVIRSKFRVDKKIID 62
>UniRef50_Q01W77 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Solibacter usitatus
Ellin6076|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Solibacter usitatus (strain
Ellin6076)
Length = 312
Score = 59.3 bits (137), Expect = 8e-08
Identities = 31/92 (33%), Positives = 45/92 (48%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
D++D+ +A + GV V N PG A S E T L+ +AR + A + G W+R
Sbjct: 83 DHVDLAAAARHGVTVANTPGVAARSIAEHTLALLFAVARQIPHMDAATRRGAWERG--QS 140
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNII 573
EL GKT ++ GR A A GM ++
Sbjct: 141 MELYGKTCGVIGYGAVGRHFARLATAIGMRVM 172
>UniRef50_A6G5P3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: D-3-phosphoglycerate
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 405
Score = 59.3 bits (137), Expect = 8e-08
Identities = 30/91 (32%), Positives = 46/91 (50%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
D ID++ A + GV V NAP +N S EL ++ L+R + S A GRW +
Sbjct: 77 DQIDLEVAAQSGVAVFNAPFSNTRSVAELVIAEIVCLSRQLFERSWAAHEGRWRKDAKGA 136
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNI 570
E+ GKTL I+ G +++ A G+ +
Sbjct: 137 HEVRGKTLGIIGYGHIGSQLSVLAEAMGLRV 167
>UniRef50_A5Z3X2 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 387
Score = 59.3 bits (137), Expect = 8e-08
Identities = 36/115 (31%), Positives = 55/115 (47%), Gaps = 10/115 (8%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL--- 468
+NI +D KGV V N PGANA EL ML+ +R ++ + + + +
Sbjct: 61 NNIPLDKCADKGVVVFNTPGANANGVKELVLCGMLLASRDIIGGNKWVANNTDNENISKD 120
Query: 469 -------YTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCAS 612
+ G+E+ GK L ++ L GR VA + GM + G DPF+S + S
Sbjct: 121 MEKAKKNFAGNEIKGKKLGVIGLGAIGRLVANAAESMGMEVYGNDPFISVEGALS 175
>UniRef50_Q9TXJ5 Cluster: D-3-phosphoglycerate dehydrogenase-like
protein; n=10; cellular organisms|Rep:
D-3-phosphoglycerate dehydrogenase-like protein -
Leishmania major
Length = 511
Score = 59.3 bits (137), Expect = 8e-08
Identities = 30/95 (31%), Positives = 49/95 (51%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
+ +D+D A +GV V N+P AN S EL ++ L+R + S + G W++
Sbjct: 188 NQVDLDYATTRGVAVFNSPFANTRSVAELVIGEIISLSRKMTQRSEEVHRGVWNKTHVGC 247
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
E+ GKT+ I+ G +V A GMN++ +D
Sbjct: 248 YEVRGKTVGIVGYGHIGSQVGVLAEALGMNVVFYD 282
Score = 33.1 bits (72), Expect = 5.8
Identities = 21/59 (35%), Positives = 33/59 (55%), Gaps = 1/59 (1%)
Frame = +2
Query: 86 LIVDGVGAKCAELLNAYG-IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDEA 259
L+++GV ELL + G I + ++ LL +I + L +RS TQVT+ +LD A
Sbjct: 116 LLLEGVNPIAKELLESKGCIVEYIPNALPRDTLLEKIRDVHFLGIRSKTQVTQAILDAA 174
>UniRef50_A3H6F3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Caldivirga
maquilingensis IC-167|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Caldivirga
maquilingensis IC-167
Length = 326
Score = 59.3 bits (137), Expect = 8e-08
Identities = 33/94 (35%), Positives = 52/94 (55%), Gaps = 2/94 (2%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL--Y 471
D+ID+D+A ++G+ V P + +L L++ LAR V+ +++G + +
Sbjct: 84 DHIDLDAATRRGIPVGYTPEVLVEAVADLAIGLIITLARRVIEGDRLVRSGEAYKVWGEF 143
Query: 472 TGSELAGKTLAILALAXXGREVATRMYAFGMNII 573
G+E+ GKTL IL L G VA R AF MN+I
Sbjct: 144 LGTEVWGKTLGILGLGNIGAAVARRAKAFNMNVI 177
>UniRef50_Q4AIL7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding precursor; n=1;
Chlorobium phaeobacteroides BS1|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding
precursor - Chlorobium phaeobacteroides BS1
Length = 312
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/97 (30%), Positives = 48/97 (49%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
+NID+ SA K V +NAP N + E ++L L ++ A ++ G W R G
Sbjct: 78 ENIDIQSADKHQVVCLNAPEGNRDAVAEQAVGMILTLFNRLLIADAEVRKGIWLREQNRG 137
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPF 588
EL GKT+ I+ G A ++ F + I+ +D +
Sbjct: 138 IELGGKTVGIIGYGNTGSAFARKLQGFDVRILAYDKY 174
>UniRef50_Q214B1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding precursor; n=2;
Proteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding precursor - Rhodopseudomonas
palustris (strain BisB18)
Length = 336
Score = 58.8 bits (136), Expect = 1e-07
Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 1/98 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
D +D+ +A K GV V+NAP AN+ S EL ML +R+ + + L T
Sbjct: 96 DTVDLAAAKKHGVTVLNAPLANSTSVAELALFYMLHCSRNFRLVQQTMLVDYYKAKLDTP 155
Query: 478 -SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPF 588
SE+A K L ++ + G VA F M +IGFDP+
Sbjct: 156 KSEIACKKLGLIGVGNIGSRVAKMARGFDMQVIGFDPY 193
>UniRef50_A6CRV0 Cluster: 2-hydroxyacid dehydrogenase; n=15;
Bacillales|Rep: 2-hydroxyacid dehydrogenase - Bacillus
sp. SG-1
Length = 351
Score = 58.8 bits (136), Expect = 1e-07
Identities = 31/95 (32%), Positives = 49/95 (51%), Gaps = 3/95 (3%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRAL 468
DNID+ +A +K V V N P + +LT LM+ AR ++ A ++ G+ W L
Sbjct: 106 DNIDLKAANEKDVAVCNTPDVLTDTTADLTFGLMMAAARRLIEADKYVREGKWKSWSPLL 165
Query: 469 YTGSELAGKTLAILALAXXGREVATRMYAFGMNII 573
G+++ KT+ I+ + G A R F MNI+
Sbjct: 166 MAGTDIHHKTVGIIGMGSIGEAFARRAKGFDMNIL 200
>UniRef50_A0VQR0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Dinoroseobacter shibae
DFL 12|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Dinoroseobacter shibae DFL
12
Length = 316
Score = 58.8 bits (136), Expect = 1e-07
Identities = 32/97 (32%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA-LYT 474
DNID+ + +G+ V A GAN S E T L+L R ++ ++ G W R L
Sbjct: 78 DNIDMAACAARGISVHPATGANTRSVAEYVITAALMLTRRAFMSTPEMQEGAWPRGPLGE 137
Query: 475 GSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDP 585
G E+AG+ L + + VA M I+G DP
Sbjct: 138 GGEIAGRKLGLYGCGAVAQAVARLAKPLSMTILGHDP 174
>UniRef50_Q63VJ5 Cluster: D-3-phosphoglycerate dehydrogenase; n=8;
Burkholderiaceae|Rep: D-3-phosphoglycerate dehydrogenase
- Burkholderia pseudomallei (Pseudomonas pseudomallei)
Length = 424
Score = 58.4 bits (135), Expect = 1e-07
Identities = 30/93 (32%), Positives = 44/93 (47%)
Frame = +1
Query: 304 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSE 483
+D+ +A G+ V NAP +N S EL ++L R V S AG W + E
Sbjct: 102 VDLPAAAHHGIPVFNAPFSNTRSVAELVIAEAILLLRRVPEKSVLAHAGEWAKGAGGSFE 161
Query: 484 LAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
GKT+AI+ G +V A GM ++ +D
Sbjct: 162 ARGKTIAIVGYGNIGAQVGVLAEALGMRVVYYD 194
>UniRef50_Q5KYJ7 Cluster: Dehydrogenase; n=3; Firmicutes|Rep:
Dehydrogenase - Geobacillus kaustophilus
Length = 334
Score = 58.4 bits (135), Expect = 1e-07
Identities = 32/104 (30%), Positives = 57/104 (54%), Gaps = 4/104 (3%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD----RA 465
+ +DVD+A +KG+ V N + + L+L LAR +V + +K+G W+ +
Sbjct: 80 NTVDVDAATEKGIIVANVTDYSIDEVSDHALALLLSLARKIVKLNHEVKSGTWNFNVGKP 139
Query: 466 LYTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSA 597
+Y L G+TL ++ L + +A + AFG+ +I +DP+V A
Sbjct: 140 IY---RLRGRTLGLVGLGRIPQALAKKAQAFGLRVIAYDPYVPA 180
>UniRef50_Q2NVC4 Cluster: Putative 2-hydroxyacid-family
dehydrogenase; n=1; Sodalis glossinidius str.
'morsitans'|Rep: Putative 2-hydroxyacid-family
dehydrogenase - Sodalis glossinidius (strain morsitans)
Length = 211
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/105 (34%), Positives = 58/105 (55%), Gaps = 1/105 (0%)
Frame = +1
Query: 304 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK-AGRWDRALYTGS 480
ID+D+A + ++ ++A ELT L+L LARH+VP + AL+ + W + L G
Sbjct: 86 IDLDAARAHNI-IVCGTASDAAPPMELTWALILGLARHLVPENQALRHSDPWQQIL--GM 142
Query: 481 ELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCASS 615
L GK L +L L G + + AFGM++I + + AD A++
Sbjct: 143 TLKGKLLCLLGLGKIGGAMVSVTQAFGMDVIAWSQHLDADLAAAA 187
>UniRef50_A3K878 Cluster: 2-hydroxyacid dehydrogenase; n=1;
Sagittula stellata E-37|Rep: 2-hydroxyacid dehydrogenase
- Sagittula stellata E-37
Length = 314
Score = 58.4 bits (135), Expect = 1e-07
Identities = 32/94 (34%), Positives = 49/94 (52%), Gaps = 2/94 (2%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR--ALY 471
D +DV++A + GV V N P E+T LML LA V + ++ GRW+ A+
Sbjct: 79 DAVDVEAAKEHGVRVTNTPDVLNDCVAEVTLALMLALAHRVPESHAYVRDGRWETEGAMP 138
Query: 472 TGSELAGKTLAILALAXXGREVATRMYAFGMNII 573
+EL G T+ I+ L G+ +A AF M ++
Sbjct: 139 LTAELTGATVGIIGLGRIGKAIARLAQAFSMRVV 172
>UniRef50_Q7NEV2 Cluster: Phosphoglycerate dehydrogenase; n=6;
Bacteria|Rep: Phosphoglycerate dehydrogenase -
Gloeobacter violaceus
Length = 310
Score = 58.0 bits (134), Expect = 2e-07
Identities = 29/109 (26%), Positives = 51/109 (46%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+D +A G+ + N P ++ + + LAR ++AG W + G
Sbjct: 83 DNVDFAAARALGIPIANTPAMFGAEVADVAVSYVTALARETFSVDREVRAGGWPKPC--G 140
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCASSIAP 624
LAGKT+A++ G+ A R+ A M +I +DP + + ++ P
Sbjct: 141 VSLAGKTVALVGFGDIGKATARRLVAAEMRVIAYDPRYVPEAGSEAVEP 189
>UniRef50_Q2S4S4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Salinibacter ruber DSM 13855|Rep: D-3-phosphoglycerate
dehydrogenase - Salinibacter ruber (strain DSM 13855)
Length = 512
Score = 58.0 bits (134), Expect = 2e-07
Identities = 32/95 (33%), Positives = 50/95 (52%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
D +D + +GV V+N P +N S E+ M+VLAR + A+ + W +
Sbjct: 159 DTVDKQACADEGVLVLNDPVSNGRSVVEMVMGEMVVLARRLYTANETGRRHLWTKDSTRR 218
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
EL KTL+++ L G+++A AFGMNI +D
Sbjct: 219 YELMDKTLSVIGLGNIGKQLARLADAFGMNIRFYD 253
>UniRef50_Q1FF19 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Clostridium phytofermentans ISDg|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Clostridium phytofermentans ISDg
Length = 316
Score = 58.0 bits (134), Expect = 2e-07
Identities = 34/96 (35%), Positives = 51/96 (53%), Gaps = 2/96 (2%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 474
DNID+ A +G+ V P ANA S E T L+L A+++V A L+ G ++ R
Sbjct: 76 DNIDIAEATAQGIKVCYTPLANANSVAEHTIMLLLACAKNIVIADKELRQGNYEIRNQMP 135
Query: 475 GSELAGKTLAILALAXXGREVATR-MYAFGMNIIGF 579
G ++ GKTL I+ G+ VA + GM I+ +
Sbjct: 136 GIDVFGKTLGIIGFGRIGKSVAKKAALGLGMKILAY 171
>UniRef50_A7IJ69 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Rhizobiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Xanthobacter sp. (strain Py2)
Length = 359
Score = 58.0 bits (134), Expect = 2e-07
Identities = 32/92 (34%), Positives = 50/92 (54%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
D +DVD+A G V A GAN + + T LML + R + + A+ G W R L G
Sbjct: 116 DRVDVDAARDLGRVVTIAAGANDPAVADHTIALMLAVLRRLKASQAAIARGDW-RVL-VG 173
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNII 573
++L GKT+ ++ GR+VA R+ F + ++
Sbjct: 174 ADLTGKTVGLIGFGRIGRQVARRLSGFDVTVL 205
>UniRef50_A1UEI9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=5; Mycobacterium|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Mycobacterium sp. (strain KMS)
Length = 321
Score = 58.0 bits (134), Expect = 2e-07
Identities = 37/96 (38%), Positives = 49/96 (51%), Gaps = 4/96 (4%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRAL 468
DNIDV +A GV V N PG + + T L+L + R VV L++ R W +
Sbjct: 83 DNIDVAAAHAAGVTVTNTPGVLDNATADHTFALILAVTRRVVDGDRFLRSRRPWIWGPRM 142
Query: 469 YTGSEL-AGKTLAILALAXXGREVATRMYAFGMNII 573
TG ++ AG TL IL GR VA R AF M ++
Sbjct: 143 LTGLDVSAGATLGILGYGRIGRAVARRARAFDMTVL 178
>UniRef50_Q896Z8 Cluster: 2-hydroxyacid dehydrogenase; n=4;
Clostridium|Rep: 2-hydroxyacid dehydrogenase -
Clostridium tetani
Length = 357
Score = 57.6 bits (133), Expect = 2e-07
Identities = 31/95 (32%), Positives = 54/95 (56%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
D+I++++ K + V N+ G + S ELT L+L L R++VP + ++ G + Y+
Sbjct: 122 DHINMETCRKNNIMVCNSAGYSTSSVVELTFGLILSLLRNIVPLNDEVRNGNTKQG-YSQ 180
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
+LAGKTL ++ G EV AFG N++ ++
Sbjct: 181 YDLAGKTLGVIGAGDIGTEVIRIGKAFGCNVLVYN 215
>UniRef50_P73990 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family; n=2; Cyanobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase family -
Synechocystis sp. (strain PCC 6803)
Length = 318
Score = 57.6 bits (133), Expect = 2e-07
Identities = 30/104 (28%), Positives = 54/104 (51%), Gaps = 1/104 (0%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
D ID+ +A + G+ N P ++ +++LAR + A++ G W + G
Sbjct: 85 DAIDLAAAKQLGILTSNTPNVFGDEVADVAIGYLILLARELHCIDQAVRQGEWLKI--RG 142
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPF-VSADQC 606
L GKT I+ + G+ +A R+ + G+ ++G+DP +SAD C
Sbjct: 143 HSLRGKTAGIIGVGSIGQAIAVRLQSMGLKLLGYDPHPISADFC 186
>UniRef50_Q4IV69 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic domain:D- isomer specific
2-hydroxyacid dehydrogenase, NAD binding domain; n=1;
Azotobacter vinelandii AvOP|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic domain:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD binding domain
- Azotobacter vinelandii AvOP
Length = 319
Score = 57.6 bits (133), Expect = 2e-07
Identities = 34/95 (35%), Positives = 48/95 (50%), Gaps = 4/95 (4%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD----RA 465
D ID+D A ++G+ V N+P ANA S +L L++ R++ A L+AGRW
Sbjct: 81 DGIDLDHARQRGIVVTNSPAANAASVADLAMGLLISSVRNLPAARQYLEAGRWQGNAGER 140
Query: 466 LYTGSELAGKTLAILALAXXGREVATRMYAFGMNI 570
+ L G+ L I L G VA R AF M +
Sbjct: 141 MPPVRGLGGRRLGICGLGAIGLNVAKRAAAFDMEV 175
>UniRef50_Q0FY56 Cluster: Putative phosphoglycerate dehydrogenase
protein; n=1; Fulvimarina pelagi HTCC2506|Rep: Putative
phosphoglycerate dehydrogenase protein - Fulvimarina
pelagi HTCC2506
Length = 322
Score = 57.6 bits (133), Expect = 2e-07
Identities = 36/113 (31%), Positives = 53/113 (46%), Gaps = 4/113 (3%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD--RALY 471
D I V +A + G+ V N P NA S E L++ LAR +V ++ W RA
Sbjct: 70 DFIPVQAASRLGIAVTNTPSVNAKSVAEHVFGLIICLARRIVENDAGIRRNEWHALRAAA 129
Query: 472 TGS-ELAGKTLAILALAXXGREVA-TRMYAFGMNIIGFDPFVSADQCASSIAP 624
GS E+AGK L ++ G+ +A FGMN++ + D+ S P
Sbjct: 130 PGSCEIAGKALGLIGYGGIGQAIAQIGKLGFGMNVLAATRWPREDEDGVSFHP 182
>UniRef50_Q4WMF4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=21; Pezizomycotina|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Aspergillus fumigatus (Sartorya fumigata)
Length = 343
Score = 57.6 bits (133), Expect = 2e-07
Identities = 37/98 (37%), Positives = 54/98 (55%), Gaps = 5/98 (5%)
Frame = +1
Query: 301 NIDVDSAGKKGVGVINA----PGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL 468
++D+ + +G+ V PG N S + T L+L LARHV A+KAG+W +L
Sbjct: 89 SLDLPALTARGIPVAGTVGRPPGVN--STVQHTWALILALARHVARDDAAVKAGKWQGSL 146
Query: 469 YTGSELAGKTLAILALAXXGREVA-TRMYAFGMNIIGF 579
G L+GKTLA+L L G +V + AFGM +I +
Sbjct: 147 --GVNLSGKTLALLGLGKLGAQVGRIAVLAFGMRVIAW 182
>UniRef50_Q9HK29 Cluster: 2-hydroxyacid dehydrogenase related
protein; n=4; Thermoplasmatales|Rep: 2-hydroxyacid
dehydrogenase related protein - Thermoplasma acidophilum
Length = 309
Score = 57.6 bits (133), Expect = 2e-07
Identities = 31/92 (33%), Positives = 51/92 (55%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+D+++ K G+ V N P A+A S E +++L L + +++GRW R +
Sbjct: 73 DNVDMNAMKKNGIMVSNIPTASADSVAEHALSMVLSLIKDQRFLDAEIRSGRWPR-ITRS 131
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNII 573
S+L GKT I+ + GR +A R+ F + II
Sbjct: 132 SDLMGKTFGIVGMGSIGRALAARLLPFKVAII 163
>UniRef50_Q5FUD9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Gluconobacter oxydans|Rep: D-3-phosphoglycerate
dehydrogenase - Gluconobacter oxydans (Gluconobacter
suboxydans)
Length = 314
Score = 57.2 bits (132), Expect = 3e-07
Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 2/97 (2%)
Frame = +1
Query: 316 SAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYTGSELAG 492
+A +GV V NAP N+ S E+T L+L + R + A A++ G W+ R G EL
Sbjct: 81 AAAARGVLVTNAPNTNSRSVAEMTIGLLLAVVRRLCEADLAVREGNWEFRYTGKGMELHT 140
Query: 493 KTLAILALAXXGREVA-TRMYAFGMNIIGFDPFVSAD 600
+TL ++ R VA GM ++ + P V AD
Sbjct: 141 RTLGLVGFGAIARHVAQIAGQGLGMRVMAWSPSVPAD 177
>UniRef50_Q1LCR9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Ralstonia metallidurans
CH34|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Ralstonia metallidurans (strain CH34 /
ATCC 43123 / DSM 2839)
Length = 317
Score = 57.2 bits (132), Expect = 3e-07
Identities = 30/91 (32%), Positives = 46/91 (50%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
+NI+ D+A +GV V +AP N+ + +ML +R + LKAG+WD
Sbjct: 81 ENIERDAARMRGVRVCHAPDTNSQVVADHALAMMLAWSRGIAMLDRGLKAGQWDALRAPR 140
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNI 570
+ GKTL I+ L G+ +A A GM +
Sbjct: 141 PGVRGKTLGIVGLGNIGQRLAALAEAVGMRV 171
>UniRef50_Q126V3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Polaromonas sp. (strain JS666 / ATCC
BAA-500)
Length = 315
Score = 57.2 bits (132), Expect = 3e-07
Identities = 29/92 (31%), Positives = 52/92 (56%), Gaps = 1/92 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DRALYT 474
D +DV +A ++ + V + PG +L LML +AR + A +++GRW + +
Sbjct: 78 DGVDVTAALERNIRVTHTPGVLNDDVADLAIGLMLSVARRIPQADQYVRSGRWPEGPMPL 137
Query: 475 GSELAGKTLAILALAXXGREVATRMYAFGMNI 570
+++G+ L I+ L G+ +ATR AFGM++
Sbjct: 138 ARKVSGERLGIVGLGRIGQAIATRAEAFGMSV 169
>UniRef50_A4AN91 Cluster: Predicted dehydrogenase; n=14;
Bacteroidetes|Rep: Predicted dehydrogenase -
Flavobacteriales bacterium HTCC2170
Length = 337
Score = 57.2 bits (132), Expect = 3e-07
Identities = 30/95 (31%), Positives = 51/95 (53%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
+NIDV A KK + + AP N + E T ++L L ++ A+ ++ G+WDR G
Sbjct: 100 ENIDVAYAKKKNIFLAAAPEGNRNAVGEHTLGMLLSLFNNLNKANLEVRNGKWDREGNRG 159
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
EL GKT+ I+ G+ A ++ F + ++ +D
Sbjct: 160 VELDGKTVGIIGYGNMGKAFAKKLRGFDVEVLCYD 194
>UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=3; Desulfovibrio|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Desulfovibrio desulfuricans (strain G20)
Length = 305
Score = 56.8 bits (131), Expect = 4e-07
Identities = 32/96 (33%), Positives = 48/96 (50%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+D+++A +G+ V N P + ELT L L L R V L++G W + + G
Sbjct: 81 DNVDMEAARARGIAVRNTPDGPTQAVAELTLGLALDLMRQVSRMDRELRSGVWKKRM--G 138
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDP 585
+ L GK L I+ + GR VA G+ + DP
Sbjct: 139 NLLGGKRLGIVGMGRIGRAVADIFTPLGVQVAFNDP 174
>UniRef50_Q125T3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Polaromonas sp.
JS666|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Polaromonas sp. (strain
JS666 / ATCC BAA-500)
Length = 309
Score = 56.8 bits (131), Expect = 4e-07
Identities = 32/90 (35%), Positives = 47/90 (52%), Gaps = 1/90 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DRALYT 474
D I V A +G+ V + PG + CEL L+L L R + + ++ GRW D A
Sbjct: 73 DGIPVAYAQARGIAVTHTPGVLDDAVCELGVGLLLGLLRDIPASDRFVRDGRWSDSAYPL 132
Query: 475 GSELAGKTLAILALAXXGREVATRMYAFGM 564
+ LAGK + I+ L GR +A R+ FG+
Sbjct: 133 TTSLAGKAVGIVGLGRIGRGIAARLQPFGV 162
>UniRef50_A1HQU2 Cluster: Glyoxylate reductase; n=1; Thermosinus
carboxydivorans Nor1|Rep: Glyoxylate reductase -
Thermosinus carboxydivorans Nor1
Length = 324
Score = 56.8 bits (131), Expect = 4e-07
Identities = 31/94 (32%), Positives = 49/94 (52%), Gaps = 2/94 (2%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW--DRALY 471
DN+D+ + ++G+ N PG + +LT L+L AR + + +GRW + +
Sbjct: 80 DNVDIAACTRRGIPFGNTPGVLVEATADLTFGLLLCAARRIHEGWNQVASGRWLNNHDVP 139
Query: 472 TGSELAGKTLAILALAXXGREVATRMYAFGMNII 573
G +L GKTL I+ + G VA R A GM +I
Sbjct: 140 FGIDLYGKTLGIVGMGRIGAAVARRAKACGMKVI 173
>UniRef50_A0HBX6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Comamonas testosteroni
KF-1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Comamonas testosteroni KF-1
Length = 320
Score = 56.8 bits (131), Expect = 4e-07
Identities = 31/101 (30%), Positives = 48/101 (47%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
D++D+++A +GV V A ANA + E LML L R + ++AG W + + G
Sbjct: 86 DSVDMEAARTQGVAVAVAQAANAPAVAEHALALMLALVRQLPQLDQQVRAGGWAGSNWQG 145
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSAD 600
+ G T+ I+ GR A A G ++ P AD
Sbjct: 146 RDFRGSTVGIVGYGAIGRATAQLAAALGAKVLVLRPAGQAD 186
>UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Oceanicaulis alexandrii HTCC2633
Length = 407
Score = 56.4 bits (130), Expect = 5e-07
Identities = 28/95 (29%), Positives = 50/95 (52%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
+ +D+ +A ++GV V NAP AN S ELT +++L R + A++ G W +
Sbjct: 83 NQVDLVAAAERGVPVFNAPFANTRSVAELTMASVIMLMRRIPEKMFAIQRGEWLKTADGA 142
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
+E+ K L I+ G +++ A GM++ +D
Sbjct: 143 NEVRKKKLGIIGYGNIGAQLSVIASALGMHVYYYD 177
>UniRef50_A2QX18 Cluster: Contig An11c0250, complete genome; n=3;
Trichocomaceae|Rep: Contig An11c0250, complete genome -
Aspergillus niger
Length = 336
Score = 56.4 bits (130), Expect = 5e-07
Identities = 31/92 (33%), Positives = 48/92 (52%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
D ID ++ K+G+ V NAP + +L L+L R++ PA +L AG + + + G
Sbjct: 91 DPIDTEACAKRGIIVTNAPDPVTDATADLAVLLLLGALRNLNPAIRSLYAGTFKQGVGFG 150
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNII 573
+ GKTL IL + GR V R FG+ +
Sbjct: 151 HDPQGKTLGILGMGRIGRAVKQRCEPFGIKTV 182
>UniRef50_Q8TR50 Cluster: Glycerate dehydrogenase; n=2;
Methanosarcina|Rep: Glycerate dehydrogenase -
Methanosarcina acetivorans
Length = 319
Score = 56.4 bits (130), Expect = 5e-07
Identities = 31/92 (33%), Positives = 44/92 (47%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+D++ A GV V N P S E L L L R V A L+ G +D Y G
Sbjct: 77 DNVDLEEATDHGVIVSNVPSYAFESVAEFVFALTLNLLRRVHLADMNLREGLFDWKYYVG 136
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNII 573
++L KT+ +L G+ V + F MN++
Sbjct: 137 NQLMSKTIGVLGTGEIGKRVIQIAHGFNMNVL 168
>UniRef50_A1S0J0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Thermofilum pendens Hrk
5|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Thermofilum pendens (strain Hrk 5)
Length = 320
Score = 56.4 bits (130), Expect = 5e-07
Identities = 34/111 (30%), Positives = 51/111 (45%), Gaps = 2/111 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+D++ ++GV V + G NA + E L+L LA+ VV +K G W
Sbjct: 72 DNLDLEYLFERGVKVATSKGCNARAVAEHAFALILALAKRVVEQDGEVKRGLWRSFTEEN 131
Query: 478 --SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCASSIAP 624
++L G T+ I+ GREVA AF M ++ D A + P
Sbjct: 132 FLADLDGSTVTIVGYGNIGREVARIAKAFNMRVLAVKKNPEKDSLADEVYP 182
>UniRef50_P0A9T3 Cluster: D-3-phosphoglycerate dehydrogenase; n=185;
Bacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Shigella flexneri
Length = 410
Score = 56.4 bits (130), Expect = 5e-07
Identities = 29/95 (30%), Positives = 47/95 (49%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
+ +D+D+A K+G+ V NAP +N S EL +L+L R V A+ G W++
Sbjct: 87 NQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGS 146
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
E GK L I+ G ++ + GM + +D
Sbjct: 147 FEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYD 181
>UniRef50_Q6FCL4 Cluster: 2-keto-D-gluconate reductase; n=15;
Pseudomonadales|Rep: 2-keto-D-gluconate reductase -
Acinetobacter sp. (strain ADP1)
Length = 321
Score = 55.6 bits (128), Expect = 9e-07
Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 4/96 (4%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR---AL 468
DN DV +K + + + P + +L TL++ AR V KAG W R A
Sbjct: 78 DNYDVQYLNQKKIWLAHTPHVLTETTADLAFTLLVSAARKVPQLDAWTKAGEWKRTVGAA 137
Query: 469 YTGSELAGKTLAILALAXXGREVATR-MYAFGMNII 573
G ++ GKTL I+ L G +A R +Y F MNI+
Sbjct: 138 QFGQDIFGKTLGIIGLGNIGAAIARRGLYGFNMNIL 173
>UniRef50_A7HBU0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Anaeromyxobacter|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Anaeromyxobacter sp. Fw109-5
Length = 313
Score = 55.6 bits (128), Expect = 9e-07
Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 3/99 (3%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW---DRAL 468
+++D+D+ ++GV V N PG + + L+L AR VV ++AG W D A
Sbjct: 78 NHLDLDACRRRGVLVTNTPGVVTDATADHAMALLLAAARRVVEGDRVVRAGGWTEVDPAW 137
Query: 469 YTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDP 585
G+E+ GKT+ ++ G+ A R F ++ P
Sbjct: 138 MLGTEVTGKTVGVVGFGRIGQAFARRARGFDTRVLYTSP 176
>UniRef50_Q931A1 Cluster: Putative; n=2; Rhizobiales|Rep: Putative -
Rhizobium meliloti (Sinorhizobium meliloti)
Length = 317
Score = 55.2 bits (127), Expect = 1e-06
Identities = 30/93 (32%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW--DRALY 471
D +D+ A ++ + V PG A +L LML + R V ++ GRW L
Sbjct: 82 DKVDLARARRRNIDVTTTPGVLADDVADLGIALMLAVLRRVGDGDRLVREGRWAAGEQLP 141
Query: 472 TGSELAGKTLAILALAXXGREVATRMYAFGMNI 570
G GK + +L L GR +A+R AFGM++
Sbjct: 142 LGHSPKGKRIGVLGLGQIGRALASRAEAFGMSV 174
>UniRef50_Q89EL0 Cluster: Blr7063 protein; n=1; Bradyrhizobium
japonicum|Rep: Blr7063 protein - Bradyrhizobium
japonicum
Length = 387
Score = 55.2 bits (127), Expect = 1e-06
Identities = 30/101 (29%), Positives = 49/101 (48%), Gaps = 3/101 (2%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR---AL 468
D++DV +A +G+ V N P + L+L R +V +++GRW AL
Sbjct: 124 DSVDVKAATARGIPVTNIPDTFIEEVADHAMMLLLAGFRRLVEQDRMVRSGRWAEGRPAL 183
Query: 469 YTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFV 591
L G+TL ++ R VA R FG+ ++ +DPF+
Sbjct: 184 LKIPRLMGQTLGFISFGRVARAVAKRAAPFGLRMMAYDPFI 224
>UniRef50_Q0B1Q1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=5; Burkholderia|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Burkholderia cepacia (strain ATCC 53795 /
AMMD)
Length = 320
Score = 55.2 bits (127), Expect = 1e-06
Identities = 34/99 (34%), Positives = 49/99 (49%), Gaps = 4/99 (4%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL--- 468
D++DV +A ++G+ V NAP A + T LML R ++AG W ++
Sbjct: 84 DHLDVAAARERGIVVSNAPDALTDCTADFTMLLMLAACRRASEYERIVRAG-WGKSFGMT 142
Query: 469 -YTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
G+ + GKTL I+ GR VA R FGM I+ D
Sbjct: 143 DMLGTRVNGKTLGIVGFGRIGRAVAQRARGFGMKIVYTD 181
>UniRef50_A2A023 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Flexibacteraceae|Rep: D-3-phosphoglycerate dehydrogenase
- Microscilla marina ATCC 23134
Length = 316
Score = 55.2 bits (127), Expect = 1e-06
Identities = 30/96 (31%), Positives = 49/96 (51%), Gaps = 1/96 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
D ID+ +A +G+ V+NAP N + E T ++L L +V A +K W R G
Sbjct: 77 DKIDLSAANARGIKVLNAPEGNRDAVGEQTIGMLLSLLHNVQRADWEVKNFAWKREANRG 136
Query: 478 SELAGKTLAILALAXXGREVATRMYAFG-MNIIGFD 582
EL K + ++ G+ A R+ +FG ++I +D
Sbjct: 137 VELMDKVVGVIGYGNMGKAFAKRLSSFGCKDVIAYD 172
>UniRef50_Q5KQ73 Cluster: D-3-phosphoglycerate dehydrogenase,
putative; n=3; Filobasidiella neoformans|Rep:
D-3-phosphoglycerate dehydrogenase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 594
Score = 55.2 bits (127), Expect = 1e-06
Identities = 40/112 (35%), Positives = 58/112 (51%), Gaps = 5/112 (4%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL--Y 471
D ID+ +A K G+ V+N PG NA + EL +ML LAR ++ G L +
Sbjct: 110 DKIDIVNAKKLGIPVMNTPGVNAQAVAELAFGMMLSLARQTPSIDRKIRKGASVTKLDGW 169
Query: 472 TGSELAGKTLAILALAXXGREVATRMY--AFGMNIIGFDPFV-SADQCASSI 618
G L GKTL ++ G VA +M+ AF I+ +DP++ S D S+I
Sbjct: 170 KGQMLYGKTLGVIGGGNIGLLVA-KMFAGAFSGKIVLYDPYLKSLDTWHSAI 220
>UniRef50_Q0CUD5 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 743
Score = 55.2 bits (127), Expect = 1e-06
Identities = 31/98 (31%), Positives = 49/98 (50%), Gaps = 1/98 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
+ ID D+ K+G+ ++N PGANA EL TL L +AR + +T + + G
Sbjct: 509 EKIDQDACVKRGIKILNTPGANARDVAELVVTLALSVARGIRSITTRQMSKPVPKETCNG 568
Query: 478 SELAGKTLAILALAXXGREVATRMY-AFGMNIIGFDPF 588
L KT+ I+ + GR VA F +I+ +D +
Sbjct: 569 LTLYQKTIGIIGMGNIGRTVAEIFRGGFAADIVAYDAY 606
>UniRef50_Q6A895 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Actinomycetales|Rep: D-3-phosphoglycerate dehydrogenase
- Propionibacterium acnes
Length = 417
Score = 54.8 bits (126), Expect = 2e-06
Identities = 30/110 (27%), Positives = 54/110 (49%), Gaps = 5/110 (4%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
+ +D+D+ + GV NAP +N S EL ++ LAR + +T + G W ++
Sbjct: 98 NQMDLDALAEAGVPAFNAPYSNTRSVVELVMAEIIALARRLGDRNTQMHNGVWRKSAIGS 157
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFD-----PFVSADQCAS 612
E+ G+ L I+ G++++ A GM + +D P +A +C S
Sbjct: 158 HEIRGRRLGIIGYGNIGQQLSVVAEAMGMQVFFYDIADVLPMGNAHKCDS 207
>UniRef50_Q5FKH9 Cluster: Glyoxylate reductase; n=1; Lactobacillus
acidophilus|Rep: Glyoxylate reductase - Lactobacillus
acidophilus
Length = 321
Score = 54.8 bits (126), Expect = 2e-06
Identities = 34/95 (35%), Positives = 49/95 (51%), Gaps = 3/95 (3%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW---DRAL 468
D+ID+D A +KG+ V N P + EL T+++ AR + AL+ G + D
Sbjct: 81 DHIDIDYAREKGIVVTNCPNSVLRPTAELALTMIMASARRIRYYDHALREGVFLNVDEYD 140
Query: 469 YTGSELAGKTLAILALAXXGREVATRMYAFGMNII 573
G + GKTL IL + G++VA A GM II
Sbjct: 141 SQGYTIEGKTLGILGMGRIGQQVARFAKALGMKII 175
>UniRef50_Q2LUG0 Cluster: 2-hydroxyacid dehydrogenase, D-isomer
specific; n=1; Syntrophus aciditrophicus SB|Rep:
2-hydroxyacid dehydrogenase, D-isomer specific -
Syntrophus aciditrophicus (strain SB)
Length = 326
Score = 54.8 bits (126), Expect = 2e-06
Identities = 29/95 (30%), Positives = 47/95 (49%), Gaps = 3/95 (3%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD---RAL 468
+++ + S +G+ ++N G + +L TL+L L R V +++G W L
Sbjct: 93 NHLPITSCQSRGIRIVNTQGVLTDATADLALTLLLSLTRRVREGEALVRSGHWKGWAPDL 152
Query: 469 YTGSELAGKTLAILALAXXGREVATRMYAFGMNII 573
G+ L GKT IL GR A R++A GM +I
Sbjct: 153 LLGTGLTGKTCGILGSGPIGRAFARRVWAIGMKVI 187
>UniRef50_A4ARG6 Cluster: D-3-phosphoglycerate dehydrogenase; n=14;
Bacteroidetes|Rep: D-3-phosphoglycerate dehydrogenase -
Flavobacteriales bacterium HTCC2170
Length = 329
Score = 54.8 bits (126), Expect = 2e-06
Identities = 36/104 (34%), Positives = 50/104 (48%), Gaps = 6/104 (5%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLM------LVLARHVVPASTALKAGRWD 459
DNIDV A +KG+ VIN P A++ S EL + L A +P K +
Sbjct: 89 DNIDVAYAKEKGLHVINTPAASSESVAELVFAHLFGGVRFLYDANRNMPLEGDSKFKQLK 148
Query: 460 RALYTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFV 591
++ GSEL GKTL ++ G+ A GM +I DPF+
Sbjct: 149 KSYAGGSELRGKTLGVIGFGRIGQATAKIALGIGMKVIYSDPFI 192
Score = 34.3 bits (75), Expect = 2.5
Identities = 26/65 (40%), Positives = 37/65 (56%), Gaps = 3/65 (4%)
Frame = +2
Query: 68 VDIKSVLIVDGVGAKCAELLNAYG--IATTTKAKISKEELLMEIPNHDA-LVVRSATQVT 238
V+ +L DG+ L A G I+TTT A+ +E + E N A L+VRSATQV
Sbjct: 11 VNSMKILANDGISQTGINELEAAGFEISTTTVAQEQLKEFINE--NQIAGLLVRSATQVR 68
Query: 239 KEVLD 253
K+++D
Sbjct: 69 KDIID 73
>UniRef50_A0LN07 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Syntrophobacter
fumaroxidans MPOB|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 317
Score = 54.8 bits (126), Expect = 2e-06
Identities = 34/97 (35%), Positives = 49/97 (50%), Gaps = 2/97 (2%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 474
D ID+ A ++GV V+ P AN S E + ++LA+ + AL+ G W R
Sbjct: 78 DAIDLRCAKERGVKVVFTPTANTESVAEHFVGMAIMLAKMIRTGDIALRTGDWAARNRLI 137
Query: 475 GSELAGKTLAILALAXXGREVA-TRMYAFGMNIIGFD 582
G+EL GK L +L GR+ A F MN+I +D
Sbjct: 138 GTELHGKALGVLGFGRIGRQTARICRNGFAMNVIYYD 174
>UniRef50_A0GDF1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Burkholderia
phytofirmans PsJN|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 274
Score = 54.4 bits (125), Expect = 2e-06
Identities = 29/98 (29%), Positives = 52/98 (53%), Gaps = 6/98 (6%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA---- 465
+++D ++ K+G+G++ PG + +S E LML L R+++P + AG W +
Sbjct: 40 NHLDTETCRKRGIGIVACPGYSTISVPEHAFALMLALRRNLMPYWHDVYAGGWSGSPTFY 99
Query: 466 --LYTGSELAGKTLAILALAXXGREVATRMYAFGMNII 573
L+ +L G TL I+ G+ +A AFGM ++
Sbjct: 100 AELHPIQDLHGSTLGIVGAGHGGKRLAELARAFGMRVL 137
>UniRef50_A7EUN0 Cluster: Formate dehydrogenase; n=2;
Sclerotiniaceae|Rep: Formate dehydrogenase - Sclerotinia
sclerotiorum 1980
Length = 436
Score = 54.4 bits (125), Expect = 2e-06
Identities = 31/91 (34%), Positives = 48/91 (52%), Gaps = 4/91 (4%)
Frame = +1
Query: 298 DNIDVDSAGKK--GVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 471
D++D+++A K G+ V G+N +S E +LVL R+ VPA ++AG WD A
Sbjct: 159 DHVDLNAANKTNGGITVAEVTGSNVVSVAEHVVMTILVLVRNFVPAHEQIQAGEWDVAAA 218
Query: 472 TGSE--LAGKTLAILALAXXGREVATRMYAF 558
+E L GK + +A+ G V R+ F
Sbjct: 219 AKNEFDLEGKVVGTVAVGRIGERVLRRLKPF 249
>UniRef50_Q5BU19 Cluster: Ribeye a protein; n=4; Clupeocephala|Rep:
Ribeye a protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 1147
Score = 54.0 bits (124), Expect = 3e-06
Identities = 33/105 (31%), Positives = 53/105 (50%), Gaps = 7/105 (6%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DNID+ +AG+ G+ V N P A + T +L L R A++ G +++
Sbjct: 852 DNIDIKAAGEMGIAVCNIPSAAVEETADSTLCHILNLYRRNTWLYQAMREGTRVQSVEQI 911
Query: 478 SELA-------GKTLAILALAXXGREVATRMYAFGMNIIGFDPFV 591
E+A G+TL ++ G+ VA R AFG N+I +DP++
Sbjct: 912 REVASGAARIRGETLGLIGFGRSGQAVAVRAKAFGFNVIFYDPYL 956
>UniRef50_Q6AMI7 Cluster: Related to D-3-phosphoglycerate
dehydrogenase; n=1; Desulfotalea psychrophila|Rep:
Related to D-3-phosphoglycerate dehydrogenase -
Desulfotalea psychrophila
Length = 393
Score = 54.0 bits (124), Expect = 3e-06
Identities = 35/108 (32%), Positives = 56/108 (51%), Gaps = 12/108 (11%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHV------VPASTALKAGRWD 459
+N++V+ A KKG+ V N PGANA + +L ++ V R++ + TA+ + D
Sbjct: 62 NNVNVERATKKGICVFNTPGANANAVVDLVFPMLGVWKRNIFNGINFCKSLTAVDPDKVD 121
Query: 460 ------RALYTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDP 585
++ Y G E+AGK L ++ L G +A MN+ GFDP
Sbjct: 122 SVVEAQKSAYKGEEIAGKNLTVVGLGQIGVRLANGGIQRLMNVKGFDP 169
>UniRef50_A1RC54 Cluster: Glyoxylate reductase; n=2;
Actinomycetales|Rep: Glyoxylate reductase - Arthrobacter
aurescens (strain TC1)
Length = 329
Score = 54.0 bits (124), Expect = 3e-06
Identities = 33/108 (30%), Positives = 52/108 (48%), Gaps = 3/108 (2%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRAL 468
+NIDVD+A + G+ V N PG + ++ L+L AR VV + ++ G+ W+
Sbjct: 78 NNIDVDAATRHGILVGNTPGVLTDATADVAMLLILGTARRVVESDRVVRDGKFLGWEPEF 137
Query: 469 YTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCAS 612
G +++G L + R VA R FGM + F P D+ S
Sbjct: 138 MLGRDVSGAVLGLAGFGRIARAVARRALGFGMEEL-FSPRPPGDRPVS 184
>UniRef50_A1AQ02 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Pelobacter propionicus (strain DSM 2379)
Length = 318
Score = 54.0 bits (124), Expect = 3e-06
Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD---RAL 468
+NID+ +A +G+GV N P + + +L T ML L+ +V T L+ G D ++L
Sbjct: 80 NNIDIAAARSRGIGVCNVPSYSTDAVAQLAITFMLNLSASLVQQQTMLRRGNLDNFQKSL 139
Query: 469 YTGS-ELAGKTLAILALAXXGREVATRMYAFGMNII 573
EL GKTL ++ GR V GM II
Sbjct: 140 QLPHFELNGKTLGVIGFGEIGRRVIAIARTLGMKII 175
>UniRef50_Q27SN5 Cluster: Beta xylosidase-like protein; n=1;
Acanthamoeba castellanii|Rep: Beta xylosidase-like
protein - Acanthamoeba castellanii (Amoeba)
Length = 222
Score = 54.0 bits (124), Expect = 3e-06
Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 5/97 (5%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR----- 462
D +DV +A ++ + V N PGA + ++ L+L R A L+ G W+R
Sbjct: 56 DTVDVKAATERNIWVCNTPGAVTNATADVALYLLLAACRRATEAERFLRDGSWERQGSDI 115
Query: 463 ALYTGSELAGKTLAILALAXXGREVATRMYAFGMNII 573
+ G+ GKTL I+ + G+ +A R A M +I
Sbjct: 116 LAFWGNNPEGKTLGIIGMGNIGKALAKRAAALDMRVI 152
>UniRef50_Q5LQR6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=7;
Alphaproteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Silicibacter pomeroyi
Length = 313
Score = 53.6 bits (123), Expect = 4e-06
Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 1/92 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY-T 474
D IDV +A +G+ V N PG +L T++L+ R + ++ G W+ A +
Sbjct: 77 DAIDVAAATARGITVTNTPGVLNDDVADLAVTMLLMQCRRMEQGGAWVREGHWETANFPL 136
Query: 475 GSELAGKTLAILALAXXGREVATRMYAFGMNI 570
+ +G ++ L GRE+A R+ AF M+I
Sbjct: 137 NRKASGGVAGVVGLGRIGREIADRLAAFKMDI 168
>UniRef50_Q1GJ08 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=24; Rhodobacterales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Silicibacter sp. (strain TM1040)
Length = 322
Score = 53.6 bits (123), Expect = 4e-06
Identities = 31/95 (32%), Positives = 48/95 (50%), Gaps = 4/95 (4%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD---RAL 468
++ID ++A GV V N PGA + ++ TLML+ AR +++G+W
Sbjct: 85 NHIDAEAARAAGVEVTNTPGAVTDATADIALTLMLMTARRAGEGERLVRSGQWQGWHPTQ 144
Query: 469 YTGSELAGKTLAILALAXXGREVATRM-YAFGMNI 570
G L+GK L ++ L G +A R + FGM I
Sbjct: 145 MLGLHLSGKRLGVVGLGRIGDAIARRAHFGFGMEI 179
>UniRef50_A5N5A9 Cluster: SerA; n=1; Clostridium kluyveri DSM
555|Rep: SerA - Clostridium kluyveri DSM 555
Length = 320
Score = 53.6 bits (123), Expect = 4e-06
Identities = 29/95 (30%), Positives = 49/95 (51%), Gaps = 1/95 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
+N+D+ +A + + + NAP +N + E T L++ LA+ L+ G + G
Sbjct: 76 NNVDIKTASELSIQITNAPESNKNTVAEYTMGLIIALAKKFFLYDRGLRKGNFKVRDILG 135
Query: 478 SELAGKTLAILALAXXGREVATR-MYAFGMNIIGF 579
+L GK L I+ L G+ +A + FGM +IGF
Sbjct: 136 IDLEGKVLGIVGLGSIGKLLALKASKGFGMKVIGF 170
>UniRef50_A4AQJ2 Cluster: D-lactate dehydrogenase; n=1;
Flavobacteriales bacterium HTCC2170|Rep: D-lactate
dehydrogenase - Flavobacteriales bacterium HTCC2170
Length = 335
Score = 53.6 bits (123), Expect = 4e-06
Identities = 26/95 (27%), Positives = 49/95 (51%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
+NI + +A + G+ V NAP + + EL L++ + R ++ A + A +D+ G
Sbjct: 79 NNIQIKAAKRFGLKVANAPDYSPNAIAELAVALLMTINRKIIVADKQVHAHNFDQKNLLG 138
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFD 582
+L KT+ ++ + G + M+ FG NI+ D
Sbjct: 139 CDLVHKTVGVIGVGRIGSVMVKIMHGFGCNILAHD 173
>UniRef50_A0Z6W9 Cluster: Spermidine/putrescine ABC transporter
ATP-binding subunit; n=4; Bacteria|Rep:
Spermidine/putrescine ABC transporter ATP-binding
subunit - marine gamma proteobacterium HTCC2080
Length = 395
Score = 53.6 bits (123), Expect = 4e-06
Identities = 35/114 (30%), Positives = 57/114 (50%), Gaps = 13/114 (11%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHV---VPASTALKAGRWDRAL 468
+NI + + G+ V N PGANA + EL +L+ +R + + +L ++A+
Sbjct: 62 NNIPLSHCTELGIPVFNTPGANANAVKELVAAGLLLASRDILGGIDFVNSLSEDLDEQAM 121
Query: 469 ----------YTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSAD 600
+ G+EL GKTL +L L G VA GM+++GFDP +S +
Sbjct: 122 GPLLEAEKKRFAGAELKGKTLGVLGLGAIGSLVAQLGLELGMDVVGFDPAISIE 175
>UniRef50_Q11JF3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Mesorhizobium sp.
BNC1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Mesorhizobium sp. (strain BNC1)
Length = 312
Score = 53.2 bits (122), Expect = 5e-06
Identities = 28/92 (30%), Positives = 47/92 (51%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
+ ID+++ +K + V N G NA S E L+L + R + A A+++G W+ A Y
Sbjct: 78 EKIDMEAVREKKIIVANNAGTNAFSVAEQALGLLLAVLRDIPAAERAVRSGIWEEARYPR 137
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNII 573
+ K + I+ L G VA R+ AF ++
Sbjct: 138 PLIFEKRVGIVGLGEVGLGVAKRVQAFEATVL 169
>UniRef50_A1ZGW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Microscilla marina ATCC 23134|Rep: D-3-phosphoglycerate
dehydrogenase - Microscilla marina ATCC 23134
Length = 322
Score = 53.2 bits (122), Expect = 5e-06
Identities = 34/105 (32%), Positives = 51/105 (48%), Gaps = 3/105 (2%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW--DRALY 471
DNID + A + + V N P + E LML LAR P ++ W
Sbjct: 83 DNIDCEYARCQQILVENIPDYVHETVAEYAINLMLSLARKSWPVQQTMRQKGWFDITPAS 142
Query: 472 TGSELAGKTLAILALAXXGREVA-TRMYAFGMNIIGFDPFVSADQ 603
G+EL GKT+ ++ R VA + F M++I +DP+VSA++
Sbjct: 143 LGTELNGKTIGLVGFGRIARSVARIAHFGFQMSVIAYDPYVSAEE 187
>UniRef50_Q5KE95 Cluster: Phosphoglycerate dehydrogenase; n=2;
Filobasidiella neoformans|Rep: Phosphoglycerate
dehydrogenase - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 316
Score = 53.2 bits (122), Expect = 5e-06
Identities = 32/98 (32%), Positives = 49/98 (50%), Gaps = 2/98 (2%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYT- 474
D+ID++ +KGV ++N PG N+ ELT +L L L R V L+AG ++
Sbjct: 112 DSIDIEGCKEKGVTLMNCPGENSQVVAELTLSLTLALLRRVPELDRRLRAGETMLSINNL 171
Query: 475 GSELAGKTLAILALAXXGREVATRM-YAFGMNIIGFDP 585
G L GK + ++ ++ R A +AF I F P
Sbjct: 172 GRTLRGKVVGMVGISATARRAAAIFHHAFDCTIRTFSP 209
>UniRef50_Q8YEC6 Cluster: Gluconate 2-dehydrogenase; n=72;
Alphaproteobacteria|Rep: Gluconate 2-dehydrogenase -
Brucella melitensis
Length = 360
Score = 52.8 bits (121), Expect = 7e-06
Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 5/96 (5%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL--KAGR---WDR 462
DNIDV +A ++G+ V N P ++T L+L + R +V + + + G+ W
Sbjct: 110 DNIDVAAAARRGITVTNTPNVLTEDTADMTLALLLSVPRRLVEGANVINERHGQWPGWSP 169
Query: 463 ALYTGSELAGKTLAILALAXXGREVATRMYAFGMNI 570
G + GK L I+ + G VA R AFG++I
Sbjct: 170 TWMLGRRIWGKRLGIVGMGRIGTAVARRAKAFGLSI 205
>UniRef50_Q89LI6 Cluster: Blr4558 protein; n=6;
Bradyrhizobiaceae|Rep: Blr4558 protein - Bradyrhizobium
japonicum
Length = 329
Score = 52.8 bits (121), Expect = 7e-06
Identities = 31/101 (30%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DRALYT 474
D +DV + ++ V ++ A AN+ S E +ML LA+ + +K G+W DR
Sbjct: 84 DAVDVPALSRRKVPLMVAGSANSPSVAEQALFMMLTLAKRAQEMHSCVKDGKWADRLGML 143
Query: 475 GSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSA 597
+L GKT+ I+ G A R A M + +DP+ A
Sbjct: 144 PFDLYGKTVLIIGFGRIGTRTAKRCLAMEMRVQVYDPYKPA 184
>UniRef50_Q3A6W9 Cluster: 3-phosphoglycerate dehydrogenase; n=1;
Pelobacter carbinolicus DSM 2380|Rep: 3-phosphoglycerate
dehydrogenase - Pelobacter carbinolicus (strain DSM 2380
/ Gra Bd 1)
Length = 321
Score = 52.8 bits (121), Expect = 7e-06
Identities = 29/104 (27%), Positives = 48/104 (46%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 477
DN+D+D + ++ P A + EL +ML L+R ++ A L+ G W + G
Sbjct: 74 DNVDLDYLRNHDLKLVRIPQPGARAVAELAFGMMLALSRQILVADQLLRKGTWAKHQLRG 133
Query: 478 SELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCA 609
L K L I+ L G + A+GM ++G S ++ A
Sbjct: 134 HLLVNKQLGIVGLGNIGTLLGQMGLAWGMQVLGCVEHPSPERAA 177
>UniRef50_Q397E0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=10; Proteobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Burkholderia sp.
(strain 383) (Burkholderia cepacia (strain ATCC 17760/
NCIB 9086 / R18194))
Length = 334
Score = 52.8 bits (121), Expect = 7e-06
Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR-ALYT 474
D +D+D A +G+ V P ++ L+L+ R + ++AGRW + A
Sbjct: 100 DAVDLDRARARGIHVTTTPDVLTDDVADMAMGLILMTLRDLGAGERIVRAGRWGKTAQPL 159
Query: 475 GSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDP 585
+++ GK L I+ L GR +A R AF M + F P
Sbjct: 160 ATQVTGKRLGIVGLGRVGRAIAQRAQAFRMPVSYFGP 196
>UniRef50_Q4IXK9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic domain:D- isomer specific
2-hydroxyacid dehydrogenase, NAD binding domain; n=1;
Azotobacter vinelandii AvOP|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic domain:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD binding domain
- Azotobacter vinelandii AvOP
Length = 388
Score = 52.8 bits (121), Expect = 7e-06
Identities = 30/91 (32%), Positives = 48/91 (52%)
Frame = +1
Query: 301 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGS 480
++D+D+ ++GV V G+ ++ EL TL+L R ++PA A + GRW + G
Sbjct: 147 HLDLDACTRRGVAVAEGRGS-PIAPAELAWTLILNARRRLLPAIAAFREGRWQTNI--GE 203
Query: 481 ELAGKTLAILALAXXGREVATRMYAFGMNII 573
LAG TL I G+ +A AF M ++
Sbjct: 204 RLAGLTLGIWGYGKIGQRLARYAQAFEMPVL 234
>UniRef50_Q3DL54 Cluster: Glyoxylate reductase, NADH-dependent; n=9;
Streptococcus|Rep: Glyoxylate reductase, NADH-dependent
- Streptococcus agalactiae 515
Length = 318
Score = 52.8 bits (121), Expect = 7e-06
Identities = 30/100 (30%), Positives = 49/100 (49%), Gaps = 3/100 (3%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW---DRAL 468
D++D A +KG+ V N+P A + E+T L+L ++ + + +++G W
Sbjct: 78 DHVDTAYAKEKGIIVSNSPQAVRVPTAEMTFALILAASKRLAFYDSIVRSGEWIDPSEQR 137
Query: 469 YTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPF 588
Y G L G TL I + G VA AFGM ++ D +
Sbjct: 138 YQGLTLQGSTLGIYGMGRIGLTVANFAKAFGMTVVYNDVY 177
>UniRef50_A4A9T4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=1; Congregibacter
litoralis KT71|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Congregibacter litoralis
KT71
Length = 316
Score = 52.8 bits (121), Expect = 7e-06
Identities = 38/112 (33%), Positives = 54/112 (48%), Gaps = 1/112 (0%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DRALYT 474
DN+D+ +A ++G+ V N P +A +LT L+L R V AL+ G W A
Sbjct: 77 DNVDLVAAKERGILVSNTPVVTEDTA-DLTFALLLATCRRVGECERALRGGDWAGGAALM 135
Query: 475 GSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPFVSADQCASSIAPRW 630
G + G L I+ G+ VA R F M++ P AD AS+ A RW
Sbjct: 136 GRRVHGAKLGIIGFGAIGQAVAQRARGFDMDVGYHGPRRKADAEASTGA-RW 186
>UniRef50_Q59516 Cluster: Glycerate dehydrogenase; n=23;
Proteobacteria|Rep: Glycerate dehydrogenase -
Methylobacterium extorquens (Protomonas extorquens)
Length = 314
Score = 52.8 bits (121), Expect = 7e-06
Identities = 30/103 (29%), Positives = 51/103 (49%), Gaps = 6/103 (5%)
Frame = +1
Query: 298 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL--- 468
D +D +A +G+ V+N + E LM L R +VP + +++ G W+++
Sbjct: 77 DVVDKAAAKAQGITVVNIRNYAFNTVPEHVVGLMFALRRAIVPYANSVRRGDWNKSKQFC 136
Query: 469 ---YTGSELAGKTLAILALAXXGREVATRMYAFGMNIIGFDPF 588
Y ++AG TL I+ G+ +A R A GM ++ FD F
Sbjct: 137 YFDYPIYDIAGSTLGIIGYGALGKSIAKRAEALGMKVLAFDVF 179
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 605,088,118
Number of Sequences: 1657284
Number of extensions: 11561868
Number of successful extensions: 48648
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 43709
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 48364
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 47296372782
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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