Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= e40h0221
(764 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M23294-1|AAA52645.1| 556|Homo sapiens beta-hexosaminidase beta-... 120 8e-27
M19735-1|AAA68620.1| 544|Homo sapiens beta-hexosaminidase beta-... 120 8e-27
M13519-1|AAA51828.1| 572|Homo sapiens HEXB protein. 120 8e-27
BT009919-1|AAP88921.1| 556|Homo sapiens hexosaminidase B (beta ... 120 8e-27
BC017378-1|AAH17378.1| 556|Homo sapiens hexosaminidase B (beta ... 120 8e-27
AY643499-1|AAV48875.1| 331|Homo sapiens ENC-1AS protein. 120 8e-27
AF378118-1|AAM46114.1| 556|Homo sapiens cervical cancer proto-o... 120 8e-27
S62076-1|AAD13932.1| 529|Homo sapiens HEXA protein. 113 5e-25
M16424-1|AAB00965.1| 529|Homo sapiens HEXA protein. 113 5e-25
M13520-1|AAA51827.1| 490|Homo sapiens HEXA protein. 113 5e-25
BC084537-1|AAH84537.1| 529|Homo sapiens hexosaminidase A (alpha... 113 5e-25
BC018927-1|AAH18927.1| 529|Homo sapiens hexosaminidase A (alpha... 113 5e-25
BC001138-1|AAH01138.2| 409|Homo sapiens HEXA protein protein. 113 5e-25
AK222502-1|BAD96222.1| 529|Homo sapiens hexosaminidase A prepro... 113 5e-25
M34906-1|AAA51829.1| 58|Homo sapiens beta-hexosaminidase beta-... 75 3e-13
BC021030-1|AAH21030.1| 309|Homo sapiens HEXA protein protein. 75 3e-13
AL160175-15|CAI12821.1| 295|Homo sapiens dual specificity phosp... 31 6.0
AL160175-12|CAI12818.1| 92|Homo sapiens dual specificity phosp... 31 6.0
AK097430-1|BAC05048.1| 295|Homo sapiens A. protein. 31 6.0
>M23294-1|AAA52645.1| 556|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 556
Score = 120 bits (288), Expect = 8e-27
Identities = 51/83 (61%), Positives = 63/83 (75%)
Frame = +2
Query: 2 KMNVFHWHIVDDQSFPYQSERFPDLSRLGAYHETLIYTKENIQTVIDHARNRGIRVIPEF 181
K NV HWHIVDDQSFPYQS FP+LS G+Y + +YT +++ VI++AR RGIRV+PEF
Sbjct: 230 KFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYTPNDVRMVIEYARLRGIRVLPEF 289
Query: 182 DVPGHTRSWGVAKPDLLTHCYDQ 250
D PGHT SWG + DLLT CY +
Sbjct: 290 DTPGHTLSWGKGQKDLLTPCYSR 312
Score = 76.6 bits (180), Expect = 9e-14
Identities = 28/77 (36%), Positives = 51/77 (66%), Gaps = 1/77 (1%)
Frame = +1
Query: 271 GPMNPIKDSTYTFLQELFHEVQALFPDRYIHIGGDEVDLDCWESNPEFQRYIQEHNL-TS 447
GP+NP ++TY+FL F E+ +FPD++IH+GGDEV+ CWESNP+ Q ++++ T
Sbjct: 320 GPINPTLNTTYSFLTTFFKEISEVFPDQFIHLGGDEVEFKCWESNPKIQDFMRQKGFGTD 379
Query: 448 VADFHALFMRNTIPLLS 498
+ +++ + +++
Sbjct: 380 FKKLESFYIQKVLDIIA 396
Score = 49.2 bits (112), Expect = 2e-05
Identities = 22/52 (42%), Positives = 34/52 (65%), Gaps = 1/52 (1%)
Frame = +2
Query: 560 TIVQVWKENEAPEMLNILRAS-HQLIYSTGWYLDHLNTGGDWTEFFNKDPRD 712
TIV+VWK++ PE L+ + AS +I S WYLD ++ G DW +++ +P D
Sbjct: 419 TIVEVWKDSAYPEELSRVTASGFPVILSAPWYLDLISYGQDWRKYYKVEPLD 470
>M19735-1|AAA68620.1| 544|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 544
Score = 120 bits (288), Expect = 8e-27
Identities = 51/83 (61%), Positives = 63/83 (75%)
Frame = +2
Query: 2 KMNVFHWHIVDDQSFPYQSERFPDLSRLGAYHETLIYTKENIQTVIDHARNRGIRVIPEF 181
K NV HWHIVDDQSFPYQS FP+LS G+Y + +YT +++ VI++AR RGIRV+PEF
Sbjct: 218 KFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYTPNDVRMVIEYARLRGIRVLPEF 277
Query: 182 DVPGHTRSWGVAKPDLLTHCYDQ 250
D PGHT SWG + DLLT CY +
Sbjct: 278 DTPGHTLSWGKGQKDLLTPCYSR 300
Score = 76.6 bits (180), Expect = 9e-14
Identities = 28/77 (36%), Positives = 51/77 (66%), Gaps = 1/77 (1%)
Frame = +1
Query: 271 GPMNPIKDSTYTFLQELFHEVQALFPDRYIHIGGDEVDLDCWESNPEFQRYIQEHNL-TS 447
GP+NP ++TY+FL F E+ +FPD++IH+GGDEV+ CWESNP+ Q ++++ T
Sbjct: 308 GPINPTLNTTYSFLTTFFKEISEVFPDQFIHLGGDEVEFKCWESNPKIQDFMRQKGFGTD 367
Query: 448 VADFHALFMRNTIPLLS 498
+ +++ + +++
Sbjct: 368 FKKLESFYIQKVLDIIA 384
Score = 49.2 bits (112), Expect = 2e-05
Identities = 22/52 (42%), Positives = 34/52 (65%), Gaps = 1/52 (1%)
Frame = +2
Query: 560 TIVQVWKENEAPEMLNILRAS-HQLIYSTGWYLDHLNTGGDWTEFFNKDPRD 712
TIV+VWK++ PE L+ + AS +I S WYLD ++ G DW +++ +P D
Sbjct: 407 TIVEVWKDSAYPEELSRVTASGFPVILSAPWYLDLISYGQDWRKYYKVEPLD 458
>M13519-1|AAA51828.1| 572|Homo sapiens HEXB protein.
Length = 572
Score = 120 bits (288), Expect = 8e-27
Identities = 51/83 (61%), Positives = 63/83 (75%)
Frame = +2
Query: 2 KMNVFHWHIVDDQSFPYQSERFPDLSRLGAYHETLIYTKENIQTVIDHARNRGIRVIPEF 181
K NV HWHIVDDQSFPYQS FP+LS G+Y + +YT +++ VI++AR RGIRV+PEF
Sbjct: 246 KFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYTPNDVRMVIEYARLRGIRVLPEF 305
Query: 182 DVPGHTRSWGVAKPDLLTHCYDQ 250
D PGHT SWG + DLLT CY +
Sbjct: 306 DTPGHTLSWGKGQKDLLTPCYSR 328
Score = 76.6 bits (180), Expect = 9e-14
Identities = 28/77 (36%), Positives = 51/77 (66%), Gaps = 1/77 (1%)
Frame = +1
Query: 271 GPMNPIKDSTYTFLQELFHEVQALFPDRYIHIGGDEVDLDCWESNPEFQRYIQEHNL-TS 447
GP+NP ++TY+FL F E+ +FPD++IH+GGDEV+ CWESNP+ Q ++++ T
Sbjct: 336 GPINPTLNTTYSFLTTFFKEISEVFPDQFIHLGGDEVEFKCWESNPKIQDFMRQKGFGTD 395
Query: 448 VADFHALFMRNTIPLLS 498
+ +++ + +++
Sbjct: 396 FKKLESFYIQKVLDIIA 412
Score = 49.2 bits (112), Expect = 2e-05
Identities = 22/52 (42%), Positives = 34/52 (65%), Gaps = 1/52 (1%)
Frame = +2
Query: 560 TIVQVWKENEAPEMLNILRAS-HQLIYSTGWYLDHLNTGGDWTEFFNKDPRD 712
TIV+VWK++ PE L+ + AS +I S WYLD ++ G DW +++ +P D
Sbjct: 435 TIVEVWKDSAYPEELSRVTASGFPVILSAPWYLDLISYGQDWRKYYKVEPLD 486
>BT009919-1|AAP88921.1| 556|Homo sapiens hexosaminidase B (beta
polypeptide) protein.
Length = 556
Score = 120 bits (288), Expect = 8e-27
Identities = 51/83 (61%), Positives = 63/83 (75%)
Frame = +2
Query: 2 KMNVFHWHIVDDQSFPYQSERFPDLSRLGAYHETLIYTKENIQTVIDHARNRGIRVIPEF 181
K NV HWHIVDDQSFPYQS FP+LS G+Y + +YT +++ VI++AR RGIRV+PEF
Sbjct: 230 KFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYTPNDVRMVIEYARLRGIRVLPEF 289
Query: 182 DVPGHTRSWGVAKPDLLTHCYDQ 250
D PGHT SWG + DLLT CY +
Sbjct: 290 DTPGHTLSWGKGQKDLLTPCYSR 312
Score = 76.6 bits (180), Expect = 9e-14
Identities = 28/77 (36%), Positives = 51/77 (66%), Gaps = 1/77 (1%)
Frame = +1
Query: 271 GPMNPIKDSTYTFLQELFHEVQALFPDRYIHIGGDEVDLDCWESNPEFQRYIQEHNL-TS 447
GP+NP ++TY+FL F E+ +FPD++IH+GGDEV+ CWESNP+ Q ++++ T
Sbjct: 320 GPINPTLNTTYSFLTTFFKEISEVFPDQFIHLGGDEVEFKCWESNPKIQDFMRQKGFGTD 379
Query: 448 VADFHALFMRNTIPLLS 498
+ +++ + +++
Sbjct: 380 FKKLESFYIQKVLDIIA 396
Score = 49.2 bits (112), Expect = 2e-05
Identities = 22/52 (42%), Positives = 34/52 (65%), Gaps = 1/52 (1%)
Frame = +2
Query: 560 TIVQVWKENEAPEMLNILRAS-HQLIYSTGWYLDHLNTGGDWTEFFNKDPRD 712
TIV+VWK++ PE L+ + AS +I S WYLD ++ G DW +++ +P D
Sbjct: 419 TIVEVWKDSAYPEELSRVTASGFPVILSAPWYLDLISYGQDWRKYYKVEPLD 470
>BC017378-1|AAH17378.1| 556|Homo sapiens hexosaminidase B (beta
polypeptide) protein.
Length = 556
Score = 120 bits (288), Expect = 8e-27
Identities = 51/83 (61%), Positives = 63/83 (75%)
Frame = +2
Query: 2 KMNVFHWHIVDDQSFPYQSERFPDLSRLGAYHETLIYTKENIQTVIDHARNRGIRVIPEF 181
K NV HWHIVDDQSFPYQS FP+LS G+Y + +YT +++ VI++AR RGIRV+PEF
Sbjct: 230 KFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYTPNDVRMVIEYARLRGIRVLPEF 289
Query: 182 DVPGHTRSWGVAKPDLLTHCYDQ 250
D PGHT SWG + DLLT CY +
Sbjct: 290 DTPGHTLSWGKGQKDLLTPCYSR 312
Score = 76.6 bits (180), Expect = 9e-14
Identities = 28/77 (36%), Positives = 51/77 (66%), Gaps = 1/77 (1%)
Frame = +1
Query: 271 GPMNPIKDSTYTFLQELFHEVQALFPDRYIHIGGDEVDLDCWESNPEFQRYIQEHNL-TS 447
GP+NP ++TY+FL F E+ +FPD++IH+GGDEV+ CWESNP+ Q ++++ T
Sbjct: 320 GPINPTLNTTYSFLTTFFKEISEVFPDQFIHLGGDEVEFKCWESNPKIQDFMRQKGFGTD 379
Query: 448 VADFHALFMRNTIPLLS 498
+ +++ + +++
Sbjct: 380 FKKLESFYIQKVLDIIA 396
Score = 49.2 bits (112), Expect = 2e-05
Identities = 22/52 (42%), Positives = 34/52 (65%), Gaps = 1/52 (1%)
Frame = +2
Query: 560 TIVQVWKENEAPEMLNILRAS-HQLIYSTGWYLDHLNTGGDWTEFFNKDPRD 712
TIV+VWK++ PE L+ + AS +I S WYLD ++ G DW +++ +P D
Sbjct: 419 TIVEVWKDSAYPEELSRVTASGFPVILSAPWYLDLISYGQDWRKYYKVEPLD 470
>AY643499-1|AAV48875.1| 331|Homo sapiens ENC-1AS protein.
Length = 331
Score = 120 bits (288), Expect = 8e-27
Identities = 51/83 (61%), Positives = 63/83 (75%)
Frame = +2
Query: 2 KMNVFHWHIVDDQSFPYQSERFPDLSRLGAYHETLIYTKENIQTVIDHARNRGIRVIPEF 181
K NV HWHIVDDQSFPYQS FP+LS G+Y + +YT +++ VI++AR RGIRV+PEF
Sbjct: 5 KFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYTPNDVRMVIEYARLRGIRVLPEF 64
Query: 182 DVPGHTRSWGVAKPDLLTHCYDQ 250
D PGHT SWG + DLLT CY +
Sbjct: 65 DTPGHTLSWGKGQKDLLTPCYSR 87
Score = 76.6 bits (180), Expect = 9e-14
Identities = 28/77 (36%), Positives = 51/77 (66%), Gaps = 1/77 (1%)
Frame = +1
Query: 271 GPMNPIKDSTYTFLQELFHEVQALFPDRYIHIGGDEVDLDCWESNPEFQRYIQEHNL-TS 447
GP+NP ++TY+FL F E+ +FPD++IH+GGDEV+ CWESNP+ Q ++++ T
Sbjct: 95 GPINPTLNTTYSFLTTFFKEISEVFPDQFIHLGGDEVEFKCWESNPKIQDFMRQKGFGTD 154
Query: 448 VADFHALFMRNTIPLLS 498
+ +++ + +++
Sbjct: 155 FKKLESFYIQKVLDIIA 171
Score = 49.2 bits (112), Expect = 2e-05
Identities = 22/52 (42%), Positives = 34/52 (65%), Gaps = 1/52 (1%)
Frame = +2
Query: 560 TIVQVWKENEAPEMLNILRAS-HQLIYSTGWYLDHLNTGGDWTEFFNKDPRD 712
TIV+VWK++ PE L+ + AS +I S WYLD ++ G DW +++ +P D
Sbjct: 194 TIVEVWKDSAYPEELSRVTASGFPVILSAPWYLDLISYGQDWRKYYKVEPLD 245
>AF378118-1|AAM46114.1| 556|Homo sapiens cervical cancer
proto-oncogene 7 protein.
Length = 556
Score = 120 bits (288), Expect = 8e-27
Identities = 51/83 (61%), Positives = 63/83 (75%)
Frame = +2
Query: 2 KMNVFHWHIVDDQSFPYQSERFPDLSRLGAYHETLIYTKENIQTVIDHARNRGIRVIPEF 181
K NV HWHIVDDQSFPYQS FP+LS G+Y + +YT +++ VI++AR RGIRV+PEF
Sbjct: 230 KFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYTPNDVRMVIEYARLRGIRVLPEF 289
Query: 182 DVPGHTRSWGVAKPDLLTHCYDQ 250
D PGHT SWG + DLLT CY +
Sbjct: 290 DTPGHTLSWGKGQKDLLTPCYSR 312
Score = 76.6 bits (180), Expect = 9e-14
Identities = 28/77 (36%), Positives = 51/77 (66%), Gaps = 1/77 (1%)
Frame = +1
Query: 271 GPMNPIKDSTYTFLQELFHEVQALFPDRYIHIGGDEVDLDCWESNPEFQRYIQEHNL-TS 447
GP+NP ++TY+FL F E+ +FPD++IH+GGDEV+ CWESNP+ Q ++++ T
Sbjct: 320 GPINPTLNTTYSFLTTFFKEISEVFPDQFIHLGGDEVEFKCWESNPKIQDFMRQKGFGTD 379
Query: 448 VADFHALFMRNTIPLLS 498
+ +++ + +++
Sbjct: 380 FKKLESFYIQKVLDIIA 396
Score = 49.2 bits (112), Expect = 2e-05
Identities = 22/52 (42%), Positives = 34/52 (65%), Gaps = 1/52 (1%)
Frame = +2
Query: 560 TIVQVWKENEAPEMLNILRAS-HQLIYSTGWYLDHLNTGGDWTEFFNKDPRD 712
TIV+VWK++ PE L+ + AS +I S WYLD ++ G DW +++ +P D
Sbjct: 419 TIVEVWKDSAYPEELSRVTASGFPVILSAPWYLDLISYGQDWRKYYKVEPLD 470
>S62076-1|AAD13932.1| 529|Homo sapiens HEXA protein.
Length = 529
Score = 113 bits (273), Expect = 5e-25
Identities = 50/82 (60%), Positives = 63/82 (76%), Gaps = 1/82 (1%)
Frame = +2
Query: 2 KMNVFHWHIVDDQSFPYQSERFPDLSRLGAYHE-TLIYTKENIQTVIDHARNRGIRVIPE 178
K+NVFHWH+VDD SFPY+S FP+L R G+Y+ T IYT ++++ VI++AR RGIRV+ E
Sbjct: 197 KLNVFHWHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAE 256
Query: 179 FDVPGHTRSWGVAKPDLLTHCY 244
FD PGHT SWG P LLT CY
Sbjct: 257 FDTPGHTLSWGPGIPGLLTPCY 278
Score = 74.9 bits (176), Expect = 3e-13
Identities = 28/54 (51%), Positives = 41/54 (75%)
Frame = +1
Query: 271 GPMNPIKDSTYTFLQELFHEVQALFPDRYIHIGGDEVDLDCWESNPEFQRYIQE 432
GP+NP ++TY F+ F EV ++FPD Y+H+GGDEVD CW+SNPE Q ++++
Sbjct: 288 GPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRK 341
Score = 44.4 bits (100), Expect = 5e-04
Identities = 19/54 (35%), Positives = 32/54 (59%), Gaps = 4/54 (7%)
Frame = +2
Query: 557 DTIVQVWKE----NEAPEMLNILRASHQLIYSTGWYLDHLNTGGDWTEFFNKDP 706
DTI+QVW+E N E+ + +A + + S WYL+ ++ G DW +F+ +P
Sbjct: 386 DTIIQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYVVEP 439
>M16424-1|AAB00965.1| 529|Homo sapiens HEXA protein.
Length = 529
Score = 113 bits (273), Expect = 5e-25
Identities = 50/82 (60%), Positives = 63/82 (76%), Gaps = 1/82 (1%)
Frame = +2
Query: 2 KMNVFHWHIVDDQSFPYQSERFPDLSRLGAYHE-TLIYTKENIQTVIDHARNRGIRVIPE 178
K+NVFHWH+VDD SFPY+S FP+L R G+Y+ T IYT ++++ VI++AR RGIRV+ E
Sbjct: 197 KLNVFHWHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAE 256
Query: 179 FDVPGHTRSWGVAKPDLLTHCY 244
FD PGHT SWG P LLT CY
Sbjct: 257 FDTPGHTLSWGPGIPGLLTPCY 278
Score = 74.9 bits (176), Expect = 3e-13
Identities = 28/54 (51%), Positives = 41/54 (75%)
Frame = +1
Query: 271 GPMNPIKDSTYTFLQELFHEVQALFPDRYIHIGGDEVDLDCWESNPEFQRYIQE 432
GP+NP ++TY F+ F EV ++FPD Y+H+GGDEVD CW+SNPE Q ++++
Sbjct: 288 GPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRK 341
Score = 44.4 bits (100), Expect = 5e-04
Identities = 19/54 (35%), Positives = 32/54 (59%), Gaps = 4/54 (7%)
Frame = +2
Query: 557 DTIVQVWKE----NEAPEMLNILRASHQLIYSTGWYLDHLNTGGDWTEFFNKDP 706
DTI+QVW+E N E+ + +A + + S WYL+ ++ G DW +F+ +P
Sbjct: 386 DTIIQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYVVEP 439
>M13520-1|AAA51827.1| 490|Homo sapiens HEXA protein.
Length = 490
Score = 113 bits (273), Expect = 5e-25
Identities = 50/82 (60%), Positives = 63/82 (76%), Gaps = 1/82 (1%)
Frame = +2
Query: 2 KMNVFHWHIVDDQSFPYQSERFPDLSRLGAYHE-TLIYTKENIQTVIDHARNRGIRVIPE 178
K+NVFHWH+VDD SFPY+S FP+L R G+Y+ T IYT ++++ VI++AR RGIRV+ E
Sbjct: 158 KLNVFHWHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAE 217
Query: 179 FDVPGHTRSWGVAKPDLLTHCY 244
FD PGHT SWG P LLT CY
Sbjct: 218 FDTPGHTLSWGPGIPGLLTPCY 239
Score = 74.9 bits (176), Expect = 3e-13
Identities = 28/54 (51%), Positives = 41/54 (75%)
Frame = +1
Query: 271 GPMNPIKDSTYTFLQELFHEVQALFPDRYIHIGGDEVDLDCWESNPEFQRYIQE 432
GP+NP ++TY F+ F EV ++FPD Y+H+GGDEVD CW+SNPE Q ++++
Sbjct: 249 GPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRK 302
Score = 44.4 bits (100), Expect = 5e-04
Identities = 19/54 (35%), Positives = 32/54 (59%), Gaps = 4/54 (7%)
Frame = +2
Query: 557 DTIVQVWKE----NEAPEMLNILRASHQLIYSTGWYLDHLNTGGDWTEFFNKDP 706
DTI+QVW+E N E+ + +A + + S WYL+ ++ G DW +F+ +P
Sbjct: 347 DTIIQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYVVEP 400
>BC084537-1|AAH84537.1| 529|Homo sapiens hexosaminidase A (alpha
polypeptide) protein.
Length = 529
Score = 113 bits (273), Expect = 5e-25
Identities = 50/82 (60%), Positives = 63/82 (76%), Gaps = 1/82 (1%)
Frame = +2
Query: 2 KMNVFHWHIVDDQSFPYQSERFPDLSRLGAYHE-TLIYTKENIQTVIDHARNRGIRVIPE 178
K+NVFHWH+VDD SFPY+S FP+L R G+Y+ T IYT ++++ VI++AR RGIRV+ E
Sbjct: 197 KLNVFHWHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAE 256
Query: 179 FDVPGHTRSWGVAKPDLLTHCY 244
FD PGHT SWG P LLT CY
Sbjct: 257 FDTPGHTLSWGPGIPGLLTPCY 278
Score = 74.9 bits (176), Expect = 3e-13
Identities = 28/54 (51%), Positives = 41/54 (75%)
Frame = +1
Query: 271 GPMNPIKDSTYTFLQELFHEVQALFPDRYIHIGGDEVDLDCWESNPEFQRYIQE 432
GP+NP ++TY F+ F EV ++FPD Y+H+GGDEVD CW+SNPE Q ++++
Sbjct: 288 GPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRK 341
Score = 44.4 bits (100), Expect = 5e-04
Identities = 19/54 (35%), Positives = 32/54 (59%), Gaps = 4/54 (7%)
Frame = +2
Query: 557 DTIVQVWKE----NEAPEMLNILRASHQLIYSTGWYLDHLNTGGDWTEFFNKDP 706
DTI+QVW+E N E+ + +A + + S WYL+ ++ G DW +F+ +P
Sbjct: 386 DTIIQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYVVEP 439
>BC018927-1|AAH18927.1| 529|Homo sapiens hexosaminidase A (alpha
polypeptide) protein.
Length = 529
Score = 113 bits (273), Expect = 5e-25
Identities = 50/82 (60%), Positives = 63/82 (76%), Gaps = 1/82 (1%)
Frame = +2
Query: 2 KMNVFHWHIVDDQSFPYQSERFPDLSRLGAYHE-TLIYTKENIQTVIDHARNRGIRVIPE 178
K+NVFHWH+VDD SFPY+S FP+L R G+Y+ T IYT ++++ VI++AR RGIRV+ E
Sbjct: 197 KLNVFHWHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAE 256
Query: 179 FDVPGHTRSWGVAKPDLLTHCY 244
FD PGHT SWG P LLT CY
Sbjct: 257 FDTPGHTLSWGPGIPGLLTPCY 278
Score = 74.9 bits (176), Expect = 3e-13
Identities = 28/54 (51%), Positives = 41/54 (75%)
Frame = +1
Query: 271 GPMNPIKDSTYTFLQELFHEVQALFPDRYIHIGGDEVDLDCWESNPEFQRYIQE 432
GP+NP ++TY F+ F EV ++FPD Y+H+GGDEVD CW+SNPE Q ++++
Sbjct: 288 GPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRK 341
Score = 44.4 bits (100), Expect = 5e-04
Identities = 19/54 (35%), Positives = 32/54 (59%), Gaps = 4/54 (7%)
Frame = +2
Query: 557 DTIVQVWKE----NEAPEMLNILRASHQLIYSTGWYLDHLNTGGDWTEFFNKDP 706
DTI+QVW+E N E+ + +A + + S WYL+ ++ G DW +F+ +P
Sbjct: 386 DTIIQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYVVEP 439
>BC001138-1|AAH01138.2| 409|Homo sapiens HEXA protein protein.
Length = 409
Score = 113 bits (273), Expect = 5e-25
Identities = 50/82 (60%), Positives = 63/82 (76%), Gaps = 1/82 (1%)
Frame = +2
Query: 2 KMNVFHWHIVDDQSFPYQSERFPDLSRLGAYHE-TLIYTKENIQTVIDHARNRGIRVIPE 178
K+NVFHWH+VDD SFPY+S FP+L R G+Y+ T IYT ++++ VI++AR RGIRV+ E
Sbjct: 77 KLNVFHWHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAE 136
Query: 179 FDVPGHTRSWGVAKPDLLTHCY 244
FD PGHT SWG P LLT CY
Sbjct: 137 FDTPGHTLSWGPGIPGLLTPCY 158
Score = 74.9 bits (176), Expect = 3e-13
Identities = 28/54 (51%), Positives = 41/54 (75%)
Frame = +1
Query: 271 GPMNPIKDSTYTFLQELFHEVQALFPDRYIHIGGDEVDLDCWESNPEFQRYIQE 432
GP+NP ++TY F+ F EV ++FPD Y+H+GGDEVD CW+SNPE Q ++++
Sbjct: 168 GPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRK 221
Score = 44.4 bits (100), Expect = 5e-04
Identities = 19/54 (35%), Positives = 32/54 (59%), Gaps = 4/54 (7%)
Frame = +2
Query: 557 DTIVQVWKE----NEAPEMLNILRASHQLIYSTGWYLDHLNTGGDWTEFFNKDP 706
DTI+QVW+E N E+ + +A + + S WYL+ ++ G DW +F+ +P
Sbjct: 266 DTIIQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYVVEP 319
>AK222502-1|BAD96222.1| 529|Homo sapiens hexosaminidase A
preproprotein variant protein.
Length = 529
Score = 113 bits (273), Expect = 5e-25
Identities = 50/82 (60%), Positives = 63/82 (76%), Gaps = 1/82 (1%)
Frame = +2
Query: 2 KMNVFHWHIVDDQSFPYQSERFPDLSRLGAYHE-TLIYTKENIQTVIDHARNRGIRVIPE 178
K+NVFHWH+VDD SFPY+S FP+L R G+Y+ T IYT ++++ VI++AR RGIRV+ E
Sbjct: 197 KLNVFHWHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAE 256
Query: 179 FDVPGHTRSWGVAKPDLLTHCY 244
FD PGHT SWG P LLT CY
Sbjct: 257 FDTPGHTLSWGPGIPGLLTPCY 278
Score = 72.9 bits (171), Expect = 1e-12
Identities = 27/54 (50%), Positives = 40/54 (74%)
Frame = +1
Query: 271 GPMNPIKDSTYTFLQELFHEVQALFPDRYIHIGGDEVDLDCWESNPEFQRYIQE 432
GP+NP ++TY F+ F EV ++FPD Y+H+GGDEVD CW+ NPE Q ++++
Sbjct: 288 GPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKPNPEIQDFMRK 341
Score = 44.4 bits (100), Expect = 5e-04
Identities = 19/54 (35%), Positives = 32/54 (59%), Gaps = 4/54 (7%)
Frame = +2
Query: 557 DTIVQVWKE----NEAPEMLNILRASHQLIYSTGWYLDHLNTGGDWTEFFNKDP 706
DTI+QVW+E N E+ + +A + + S WYL+ ++ G DW +F+ +P
Sbjct: 386 DTIIQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYVVEP 439
>M34906-1|AAA51829.1| 58|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 58
Score = 74.9 bits (176), Expect = 3e-13
Identities = 32/54 (59%), Positives = 41/54 (75%)
Frame = +2
Query: 2 KMNVFHWHIVDDQSFPYQSERFPDLSRLGAYHETLIYTKENIQTVIDHARNRGI 163
K NV HWHIVDDQSFPYQS FP+LS G+Y + +YT +++ VI++AR RGI
Sbjct: 5 KFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYTPNDVRMVIEYARLRGI 58
>BC021030-1|AAH21030.1| 309|Homo sapiens HEXA protein protein.
Length = 309
Score = 74.9 bits (176), Expect = 3e-13
Identities = 28/54 (51%), Positives = 41/54 (75%)
Frame = +1
Query: 271 GPMNPIKDSTYTFLQELFHEVQALFPDRYIHIGGDEVDLDCWESNPEFQRYIQE 432
GP+NP ++TY F+ F EV ++FPD Y+H+GGDEVD CW+SNPE Q ++++
Sbjct: 68 GPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRK 121
Score = 69.7 bits (163), Expect = 1e-11
Identities = 32/56 (57%), Positives = 41/56 (73%), Gaps = 1/56 (1%)
Frame = +2
Query: 80 RLGAYHE-TLIYTKENIQTVIDHARNRGIRVIPEFDVPGHTRSWGVAKPDLLTHCY 244
R G+Y+ T IYT ++++ VI++AR RGIRV+ EFD PGHT SWG P LLT CY
Sbjct: 3 RTGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLLTPCY 58
Score = 44.4 bits (100), Expect = 5e-04
Identities = 19/54 (35%), Positives = 32/54 (59%), Gaps = 4/54 (7%)
Frame = +2
Query: 557 DTIVQVWKE----NEAPEMLNILRASHQLIYSTGWYLDHLNTGGDWTEFFNKDP 706
DTI+QVW+E N E+ + +A + + S WYL+ ++ G DW +F+ +P
Sbjct: 166 DTIIQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYVVEP 219
>AL160175-15|CAI12821.1| 295|Homo sapiens dual specificity
phosphatase 15 protein.
Length = 295
Score = 30.7 bits (66), Expect = 6.0
Identities = 10/20 (50%), Positives = 15/20 (75%)
Frame = -2
Query: 403 STPSNLDRLHHLRCECIYPE 344
STP N D + HL+C C++P+
Sbjct: 267 STPGNPDGITHLQCSCLHPK 286
>AL160175-12|CAI12818.1| 92|Homo sapiens dual specificity
phosphatase 15 protein.
Length = 92
Score = 30.7 bits (66), Expect = 6.0
Identities = 10/20 (50%), Positives = 15/20 (75%)
Frame = -2
Query: 403 STPSNLDRLHHLRCECIYPE 344
STP N D + HL+C C++P+
Sbjct: 64 STPGNPDGITHLQCSCLHPK 83
>AK097430-1|BAC05048.1| 295|Homo sapiens A. protein.
Length = 295
Score = 30.7 bits (66), Expect = 6.0
Identities = 10/20 (50%), Positives = 15/20 (75%)
Frame = -2
Query: 403 STPSNLDRLHHLRCECIYPE 344
STP N D + HL+C C++P+
Sbjct: 267 STPGNPDGITHLQCSCLHPK 286
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 120,445,418
Number of Sequences: 237096
Number of extensions: 2944262
Number of successful extensions: 6525
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 6079
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6503
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9199990470
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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