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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= e40h0220
         (758 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_A0NBF2 Cluster: ENSANGP00000030890; n=2; Culicidae|Rep:...    80   5e-14
UniRef50_UPI00015B5DFC Cluster: PREDICTED: similar to conserved ...    77   5e-13
UniRef50_Q6NTT3 Cluster: MGC82297 protein; n=6; Tetrapoda|Rep: M...    72   1e-11
UniRef50_Q4PM62 Cluster: Putative uncharacterized protein; n=1; ...    71   2e-11
UniRef50_A7RM84 Cluster: Predicted protein; n=1; Nematostella ve...    71   2e-11
UniRef50_Q96QK8 Cluster: Uncharacterized protein C4orf34; n=21; ...    70   5e-11
UniRef50_UPI000051818F Cluster: PREDICTED: similar to CG13585-PA...    67   4e-10
UniRef50_UPI0000E4711D Cluster: PREDICTED: hypothetical protein;...    64   4e-09
UniRef50_A6YPK5 Cluster: Putative uncharacterized protein; n=1; ...    62   1e-08
UniRef50_UPI0000D5745F Cluster: PREDICTED: similar to C34C12.4; ...    59   1e-07
UniRef50_Q8MPE5 Cluster: Putative uncharacterized protein; n=1; ...    57   5e-07
UniRef50_Q0E8W6 Cluster: CG13585-PA, isoform A; n=4; Sophophora|...    54   4e-06
UniRef50_Q5DBP2 Cluster: SJCHGC06660 protein; n=1; Schistosoma j...    52   2e-05
UniRef50_Q09269 Cluster: Uncharacterized protein C34C12.4; n=2; ...    48   2e-04
UniRef50_Q4SZB8 Cluster: Chromosome undetermined SCAF11727, whol...    38   0.27 
UniRef50_UPI00006CAFC1 Cluster: hypothetical protein TTHERM_0046...    38   0.36 
UniRef50_UPI0000F3218A Cluster: Ras and Rab interactor 2 (Ras in...    33   5.8  
UniRef50_A4I4H9 Cluster: Putative uncharacterized protein; n=3; ...    33   7.7  
UniRef50_P48436 Cluster: Transcription factor SOX-9; n=145; Chor...    33   7.7  

>UniRef50_A0NBF2 Cluster: ENSANGP00000030890; n=2; Culicidae|Rep:
           ENSANGP00000030890 - Anopheles gambiae str. PEST
          Length = 102

 Score = 80.2 bits (189), Expect = 5e-14
 Identities = 34/56 (60%), Positives = 41/56 (73%)
 Frame = +3

Query: 87  MGDEMDPCECLWNHELAMRRLISLLRQGQSYCTESECLEQLPGLPQPESAGNSFIM 254
           M DE D CEC W+HELAMRRL+SLLRQGQSYC ++EC + LP LP      N F++
Sbjct: 1   MADEFDACECFWSHELAMRRLMSLLRQGQSYCNDNECTD-LPSLPNVTGGANFFLI 55


>UniRef50_UPI00015B5DFC Cluster: PREDICTED: similar to conserved
           protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to conserved protein - Nasonia vitripennis
          Length = 109

 Score = 77.0 bits (181), Expect = 5e-13
 Identities = 33/57 (57%), Positives = 42/57 (73%), Gaps = 2/57 (3%)
 Frame = +3

Query: 90  GDEMDPCECLWNHELAMRRLISLLRQGQSYCTESEC--LEQLPGLPQPESAGNSFIM 254
           G+E DPC C+WNH+LAMRRL+S+LRQ QSYCT++EC  L +LPG     +  N F M
Sbjct: 5   GEEFDPCACMWNHDLAMRRLLSILRQSQSYCTDNECLTLSRLPGPGNTPNEVNDFRM 61


>UniRef50_Q6NTT3 Cluster: MGC82297 protein; n=6; Tetrapoda|Rep:
           MGC82297 protein - Xenopus laevis (African clawed frog)
          Length = 103

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 31/56 (55%), Positives = 40/56 (71%)
 Frame = +3

Query: 102 DPCECLWNHELAMRRLISLLRQGQSYCTESECLEQLPGLPQPESAGNSFIMCS**W 269
           DPCEC+ +HE A+RRLI+LLRQ QSYCT++ECL++LPG       G S  M +  W
Sbjct: 7   DPCECICSHEHAIRRLINLLRQSQSYCTDTECLQELPGPNSSSDGGISIAMIAMAW 62


>UniRef50_Q4PM62 Cluster: Putative uncharacterized protein; n=1;
           Ixodes scapularis|Rep: Putative uncharacterized protein
           - Ixodes scapularis (Black-legged tick) (Deer tick)
          Length = 99

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 29/55 (52%), Positives = 38/55 (69%)
 Frame = +3

Query: 87  MGDEMDPCECLWNHELAMRRLISLLRQGQSYCTESECLEQLPGLPQPESAGNSFI 251
           M D  DPCEC+++H+ AM+RLISLLR  QS CT+SEC + LP +PQ       F+
Sbjct: 1   MDDGFDPCECIFSHDAAMQRLISLLRSSQSTCTDSECYQDLPAMPQGAGGSGFFL 55


>UniRef50_A7RM84 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 109

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 30/53 (56%), Positives = 40/53 (75%)
 Frame = +3

Query: 90  GDEMDPCECLWNHELAMRRLISLLRQGQSYCTESECLEQLPGLPQPESAGNSF 248
           GD  DPCEC+ +++ AMRRLISLLR  QSYCT+++CL++LPG PQ    G  +
Sbjct: 8   GDSFDPCECICSYDGAMRRLISLLRSSQSYCTDNQCLQELPG-PQGTDTGPEY 59


>UniRef50_Q96QK8 Cluster: Uncharacterized protein C4orf34; n=21;
           Euteleostomi|Rep: Uncharacterized protein C4orf34 - Homo
           sapiens (Human)
          Length = 99

 Score = 70.1 bits (164), Expect = 5e-11
 Identities = 28/38 (73%), Positives = 35/38 (92%)
 Frame = +3

Query: 102 DPCECLWNHELAMRRLISLLRQGQSYCTESECLEQLPG 215
           DPCEC+ +HE AMRRLI+LLRQ QSYCT++ECL++LPG
Sbjct: 7   DPCECVCSHEHAMRRLINLLRQSQSYCTDTECLQELPG 44


>UniRef50_UPI000051818F Cluster: PREDICTED: similar to CG13585-PA,
           isoform A; n=1; Apis mellifera|Rep: PREDICTED: similar
           to CG13585-PA, isoform A - Apis mellifera
          Length = 107

 Score = 67.3 bits (157), Expect = 4e-10
 Identities = 31/59 (52%), Positives = 41/59 (69%), Gaps = 3/59 (5%)
 Frame = +3

Query: 87  MGDE-MDPCECLWNHELAMRRLISLLRQGQSYCTESEC--LEQLPGLPQPESAGNSFIM 254
           M DE  D CEC+WNHE AM+RL+S+LRQ Q+YCT++EC  + +LPG     S   +F M
Sbjct: 1   MADEGFDLCECIWNHEFAMQRLLSILRQSQNYCTDNECFDMSRLPGPRDVPSWNLNFFM 59


>UniRef50_UPI0000E4711D Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 99

 Score = 64.1 bits (149), Expect = 4e-09
 Identities = 27/47 (57%), Positives = 39/47 (82%)
 Frame = +3

Query: 102 DPCECLWNHELAMRRLISLLRQGQSYCTESECLEQLPGLPQPESAGN 242
           DPCEC+W+HE AMRRLI++LR+ Q+ C++S+C  + PG PQP S+G+
Sbjct: 7   DPCECIWSHENAMRRLINMLRE-QNTCSDSQCDLEFPG-PQPNSSGD 51


>UniRef50_A6YPK5 Cluster: Putative uncharacterized protein; n=1;
           Triatoma infestans|Rep: Putative uncharacterized protein
           - Triatoma infestans (Assassin bug)
          Length = 100

 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 27/55 (49%), Positives = 36/55 (65%)
 Frame = +3

Query: 93  DEMDPCECLWNHELAMRRLISLLRQGQSYCTESECLEQLPGLPQPESAGNSFIMC 257
           D MD C  +WNHE+AMRRL+SLLRQ Q  CT+++C +  P  P    +G   +MC
Sbjct: 4   DGMDLCGAIWNHEMAMRRLLSLLRQSQHTCTDTQCFQ--PSNPTQGDSGLMLMMC 56


>UniRef50_UPI0000D5745F Cluster: PREDICTED: similar to C34C12.4;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           C34C12.4 - Tribolium castaneum
          Length = 92

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 23/46 (50%), Positives = 33/46 (71%)
 Frame = +3

Query: 99  MDPCECLWNHELAMRRLISLLRQGQSYCTESECLEQLPGLPQPESA 236
           MD CEC+W HELAMRRL++++R  QS C ++EC ++      PES+
Sbjct: 1   MDLCECIWGHELAMRRLLNVIRNSQSNCVDNECFDEGFQRQSPESS 46



 Score = 35.1 bits (77), Expect = 1.9
 Identities = 16/36 (44%), Positives = 23/36 (63%)
 Frame = +1

Query: 271 ICVTMYMMRPRRNQIQDAAKPAHNPHDRDGAPPTPP 378
           + + +Y  RPR  +I D  KP  +  DR+GAPP+PP
Sbjct: 56  VAMFLYYFRPRTQRIDDT-KPGRS--DRNGAPPSPP 88


>UniRef50_Q8MPE5 Cluster: Putative uncharacterized protein; n=1;
           Taenia solium|Rep: Putative uncharacterized protein -
           Taenia solium (Pork tapeworm)
          Length = 100

 Score = 56.8 bits (131), Expect = 5e-07
 Identities = 20/37 (54%), Positives = 29/37 (78%)
 Frame = +3

Query: 87  MGDEMDPCECLWNHELAMRRLISLLRQGQSYCTESEC 197
           M D  DPCEC++NHE +M+RL+++LRQ Q+YC +  C
Sbjct: 1   MADGFDPCECIYNHETSMQRLLTMLRQSQTYCNDVVC 37


>UniRef50_Q0E8W6 Cluster: CG13585-PA, isoform A; n=4;
           Sophophora|Rep: CG13585-PA, isoform A - Drosophila
           melanogaster (Fruit fly)
          Length = 110

 Score = 54.0 bits (124), Expect = 4e-06
 Identities = 23/52 (44%), Positives = 34/52 (65%), Gaps = 1/52 (1%)
 Frame = +3

Query: 87  MGDEMDPCECLWNHELAMRRLISLLRQGQSYCTESECLEQLPGLP-QPESAG 239
           M D+ D CEC+W+ E AM+RLI+ +RQ Q+ C ++EC +     P Q + AG
Sbjct: 1   MSDDFDGCECVWSQEYAMQRLINFIRQNQNACGDNECYDVTGRTPHQAQIAG 52


>UniRef50_Q5DBP2 Cluster: SJCHGC06660 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC06660 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 101

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 20/41 (48%), Positives = 29/41 (70%)
 Frame = +3

Query: 102 DPCECLWNHELAMRRLISLLRQGQSYCTESECLEQLPGLPQ 224
           D CEC+ +H  AMR+L+ +LRQ Q YC++S C++ L   PQ
Sbjct: 8   DICECIQSHNGAMRQLLGILRQTQEYCSDSSCVDDLSQTPQ 48


>UniRef50_Q09269 Cluster: Uncharacterized protein C34C12.4; n=2;
           Caenorhabditis|Rep: Uncharacterized protein C34C12.4 -
           Caenorhabditis elegans
          Length = 101

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 23/56 (41%), Positives = 36/56 (64%)
 Frame = +3

Query: 102 DPCECLWNHELAMRRLISLLRQGQSYCTESECLEQLPGLPQPESAGNSFIMCS**W 269
           DPCEC ++HE AM+RL+++LR  Q+ CT++ C     GL +    GN+ +M +  W
Sbjct: 3   DPCECFFDHESAMQRLLAMLRNSQADCTDTGC--DNDGLSR--EGGNTMMMWTLLW 54


>UniRef50_Q4SZB8 Cluster: Chromosome undetermined SCAF11727, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF11727,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 28

 Score = 37.9 bits (84), Expect = 0.27
 Identities = 14/21 (66%), Positives = 19/21 (90%)
 Frame = +3

Query: 102 DPCECLWNHELAMRRLISLLR 164
           DPCEC+ +HE AMRRL++L+R
Sbjct: 7   DPCECVCSHEYAMRRLLNLVR 27


>UniRef50_UPI00006CAFC1 Cluster: hypothetical protein
           TTHERM_00467970; n=1; Tetrahymena thermophila SB210|Rep:
           hypothetical protein TTHERM_00467970 - Tetrahymena
           thermophila SB210
          Length = 521

 Score = 37.5 bits (83), Expect = 0.36
 Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 2/58 (3%)
 Frame = +3

Query: 330 TSAQSSRP*RCSPYTSKNLINTCRGDLFIPSGRCHL*IPV--ICIINTEL*YNTDSTC 497
           T+ + S P  C+ Y + N   TCRG  ++  G CH        C I     YN D+TC
Sbjct: 358 TNGECSIP-NCTEYNADNTCKTCRGGFYLKDGTCHAQCLANGECSIANCTEYNADNTC 414



 Score = 37.1 bits (82), Expect = 0.47
 Identities = 20/58 (34%), Positives = 26/58 (44%), Gaps = 2/58 (3%)
 Frame = +3

Query: 330 TSAQSSRP*RCSPYTSKNLINTCRGDLFIPSGRCHL*IPV--ICIINTEL*YNTDSTC 497
           T+ + S P  C+ Y   N   TCRG  ++  G CH        C I     YN D+TC
Sbjct: 92  TNGECSIP-NCTEYNGDNTCKTCRGGFYLKDGTCHAQCLANGECSIANCTEYNADNTC 148



 Score = 37.1 bits (82), Expect = 0.47
 Identities = 20/58 (34%), Positives = 26/58 (44%), Gaps = 2/58 (3%)
 Frame = +3

Query: 330 TSAQSSRP*RCSPYTSKNLINTCRGDLFIPSGRCHL*IPV--ICIINTEL*YNTDSTC 497
           T+ + S P  C+ Y   N   TCRG  ++  G CH        C I     YN D+TC
Sbjct: 206 TNGECSIP-NCTEYNGDNTCKTCRGGFYLKDGTCHAQCLANGECSIANCTEYNADNTC 262



 Score = 37.1 bits (82), Expect = 0.47
 Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 2/58 (3%)
 Frame = +3

Query: 330 TSAQSSRP*RCSPYTSKNLINTCRGDLFIPSGRCHL*IPV--ICIINTEL*YNTDSTC 497
           T+ + S P  C+ Y + N   TCRG  ++  G CH        C I     YN D+TC
Sbjct: 282 TNGECSIP-NCTEYNADNTCKTCRGGFYLKDGTCHAQCLANGECSIPNCTEYNDDNTC 338



 Score = 35.9 bits (79), Expect = 1.1
 Identities = 17/48 (35%), Positives = 22/48 (45%), Gaps = 2/48 (4%)
 Frame = +3

Query: 360 CSPYTSKNLINTCRGDLFIPSGRCHL*IPV--ICIINTEL*YNTDSTC 497
           C+ Y + N   TCRG  ++  G CH        C I     YN D+TC
Sbjct: 139 CTEYNADNTCKTCRGGFYLKDGTCHAQCLANGECSIANCTEYNADNTC 186



 Score = 35.9 bits (79), Expect = 1.1
 Identities = 17/48 (35%), Positives = 22/48 (45%), Gaps = 2/48 (4%)
 Frame = +3

Query: 360 CSPYTSKNLINTCRGDLFIPSGRCHL*IPV--ICIINTEL*YNTDSTC 497
           C+ Y + N   TCRG  ++  G CH        C I     YN D+TC
Sbjct: 253 CTEYNADNTCKTCRGGFYLKDGTCHAQCLTNGECSIPNCTEYNADNTC 300



 Score = 35.5 bits (78), Expect = 1.4
 Identities = 17/48 (35%), Positives = 21/48 (43%), Gaps = 2/48 (4%)
 Frame = +3

Query: 360 CSPYTSKNLINTCRGDLFIPSGRCHL*IPV--ICIINTEL*YNTDSTC 497
           C+ Y   N   TCRG  ++  G CH        C I     YN D+TC
Sbjct: 329 CTEYNDDNTCKTCRGGFYLKDGTCHAQCLTNGECSIPNCTEYNADNTC 376



 Score = 35.1 bits (77), Expect = 1.9
 Identities = 17/48 (35%), Positives = 22/48 (45%), Gaps = 2/48 (4%)
 Frame = +3

Query: 360 CSPYTSKNLINTCRGDLFIPSGRCHL*IPV--ICIINTEL*YNTDSTC 497
           C+ Y + N   TCRG  ++  G CH        C I     YN D+TC
Sbjct: 177 CTEYNADNTCKTCRGGFYLKDGTCHAQCLTNGECSIPNCTEYNGDNTC 224



 Score = 34.7 bits (76), Expect = 2.5
 Identities = 17/48 (35%), Positives = 21/48 (43%), Gaps = 2/48 (4%)
 Frame = +3

Query: 360 CSPYTSKNLINTCRGDLFIPSGRCHL*IPV--ICIINTEL*YNTDSTC 497
           C+ Y   N   TCRG  ++  G CH        C I     YN D+TC
Sbjct: 63  CTEYNDDNTCKTCRGGFYLKDGTCHAQCLTNGECSIPNCTEYNGDNTC 110



 Score = 33.9 bits (74), Expect = 4.4
 Identities = 17/52 (32%), Positives = 24/52 (46%), Gaps = 6/52 (11%)
 Frame = +3

Query: 360 CSPYTSKNLINTCRGDLFIPSGRCHL*IPVICIINTEL------*YNTDSTC 497
           C+ Y + N   TCRG  ++  G CH      C+ N+E        +N D TC
Sbjct: 405 CTEYNADNTCKTCRGGFYLKDGTCH----AQCLANSECDIPNCSEHNADGTC 452



 Score = 33.1 bits (72), Expect = 7.7
 Identities = 16/48 (33%), Positives = 22/48 (45%), Gaps = 2/48 (4%)
 Frame = +3

Query: 360 CSPYTSKNLINTCRGDLFIPSGRCHL*IPV--ICIINTEL*YNTDSTC 497
           C+ Y + +   TCRG  ++  G CH        C I     YN D+TC
Sbjct: 25  CTEYNADDSCKTCRGGFYLKDGTCHAQCLANGECSIPNCTEYNDDNTC 72


>UniRef50_UPI0000F3218A Cluster: Ras and Rab interactor 2 (Ras
           interaction/interference protein 2) (Ras inhibitor
           JC265) (Ras association domain family 4).; n=1; Bos
           taurus|Rep: Ras and Rab interactor 2 (Ras
           interaction/interference protein 2) (Ras inhibitor
           JC265) (Ras association domain family 4). - Bos Taurus
          Length = 839

 Score = 33.5 bits (73), Expect = 5.8
 Identities = 20/70 (28%), Positives = 30/70 (42%)
 Frame = +1

Query: 151 SHCSVKANRIARKANASSNYQGFRSRSRLATASSCVRDDGICVTMYMMRPRRNQIQDAAK 330
           SHCS        +A  S   +G   R  L   ++C+RD+G       + P   +     +
Sbjct: 318 SHCSFFLTW--GRAGPSVGNRGMCPRMCLGDGNACLRDNGRAARALSVPPPPPEPASQGR 375

Query: 331 PAHNPHDRDG 360
           PA  PH R+G
Sbjct: 376 PAQTPHRREG 385


>UniRef50_A4I4H9 Cluster: Putative uncharacterized protein; n=3;
           Leishmania|Rep: Putative uncharacterized protein -
           Leishmania infantum
          Length = 477

 Score = 33.1 bits (72), Expect = 7.7
 Identities = 22/53 (41%), Positives = 26/53 (49%), Gaps = 2/53 (3%)
 Frame = +1

Query: 262 DDGICVTMYMMRPRRNQIQDAAKPAHNPHDRD--GAPPTPPRI*STLAEATCS 414
           DDG  +TM   RPRR +++ AA       D D  G P T P   ST AE   S
Sbjct: 190 DDGNLLTMLRSRPRRTEVRAAALDDDGDEDADDSGKPGTAPS--STSAEPASS 240


>UniRef50_P48436 Cluster: Transcription factor SOX-9; n=145;
           Chordata|Rep: Transcription factor SOX-9 - Homo sapiens
           (Human)
          Length = 509

 Score = 33.1 bits (72), Expect = 7.7
 Identities = 14/41 (34%), Positives = 24/41 (58%)
 Frame = +2

Query: 329 NQRTILTTVTVLPLHLQEFNQHLPRRLVHPEWSLPPLNSSY 451
           +QRT + T  + P H  E  QH P+++ +  ++LP  + SY
Sbjct: 392 SQRTHIKTEQLSPSHYSEQQQHSPQQIAYSPFNLPHYSPSY 432


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 758,263,867
Number of Sequences: 1657284
Number of extensions: 16007198
Number of successful extensions: 39844
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 38110
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 39818
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 62969581935
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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