BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= e40h0215 (574 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_A7T6B8 Cluster: Predicted protein; n=1; Nematostella ve... 145 7e-34 UniRef50_Q4S0L0 Cluster: Malic enzyme; n=2; Tetraodon nigrovirid... 141 9e-33 UniRef50_Q16798 Cluster: NADP-dependent malic enzyme, mitochondr... 138 6e-32 UniRef50_P06801 Cluster: NADP-dependent malic enzyme; n=52; cell... 138 1e-31 UniRef50_P48163 Cluster: NADP-dependent malic enzyme; n=63; Euka... 136 5e-31 UniRef50_Q5BX10 Cluster: Malic enzyme; n=1; Schistosoma japonicu... 135 8e-31 UniRef50_A2ZQ54 Cluster: Malic enzyme; n=9; Oryza sativa|Rep: Ma... 132 4e-30 UniRef50_P23368 Cluster: NAD-dependent malic enzyme, mitochondri... 132 7e-30 UniRef50_Q89G76 Cluster: Malic enzyme; n=3; cellular organisms|R... 130 3e-29 UniRef50_A0L5P5 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 126 4e-28 UniRef50_A7CWP9 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 125 6e-28 UniRef50_P16243 Cluster: NADP-dependent malic enzyme, chloroplas... 125 9e-28 UniRef50_Q0AIF8 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 124 2e-27 UniRef50_A7PC00 Cluster: Chromosome chr2 scaffold_11, whole geno... 120 2e-26 UniRef50_Q016K2 Cluster: NADP dependent malic enzyme; n=2; Ostre... 114 2e-24 UniRef50_A3QW96 Cluster: Malic enzyme; n=10; Tigriopus californi... 111 8e-24 UniRef50_P37221 Cluster: NAD-dependent malic enzyme 62 kDa isofo... 111 8e-24 UniRef50_Q8D911 Cluster: NAD-dependent malic enzyme; n=187; cell... 109 3e-23 UniRef50_A1ZAF7 Cluster: Malic enzyme; n=5; Sophophora|Rep: Mali... 109 6e-23 UniRef50_Q86NT5 Cluster: Malic enzyme; n=2; Drosophila melanogas... 108 1e-22 UniRef50_A6SA55 Cluster: Malic enzyme; n=2; Sclerotiniaceae|Rep:... 107 2e-22 UniRef50_Q8I8I4 Cluster: Malic enzyme; n=4; Eukaryota|Rep: Malic... 106 3e-22 UniRef50_A3BK03 Cluster: Malic enzyme; n=2; Oryza sativa|Rep: Ma... 104 1e-21 UniRef50_P78715 Cluster: Malic enzyme, hydrogenosomal precursor;... 104 2e-21 UniRef50_Q4X1Z2 Cluster: NADP-dependent malic enzyme MaeA; n=11;... 103 2e-21 UniRef50_UPI0000D9F768 Cluster: PREDICTED: similar to Y48B6A.12,... 103 3e-21 UniRef50_A7IMB8 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 103 3e-21 UniRef50_Q01AM5 Cluster: NADP+-dependent malic enzyme; n=2; Ostr... 103 4e-21 UniRef50_A4RZU1 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 102 5e-21 UniRef50_Q00XN9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 101 9e-21 UniRef50_Q4PC56 Cluster: Malic enzyme; n=1; Ustilago maydis|Rep:... 100 3e-20 UniRef50_A2EKE3 Cluster: Malic enzyme; n=14; Trichomonadidae|Rep... 99 8e-20 UniRef50_Q875H8 Cluster: Malic enzyme; n=1; Mucor circinelloides... 98 1e-19 UniRef50_A4RQC9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 97 3e-19 UniRef50_Q9HE50 Cluster: Malic enzyme; n=6; Pezizomycotina|Rep: ... 96 6e-19 UniRef50_A0Q531 Cluster: NAD-dependent malic enzyme; n=10; Franc... 92 7e-18 UniRef50_Q9RYN4 Cluster: Malate oxidoreductase; n=6; Deinococci|... 92 1e-17 UniRef50_Q5K758 Cluster: Malic enzyme; n=1; Filobasidiella neofo... 89 7e-17 UniRef50_Q4QAQ6 Cluster: Malic enzyme, putative; n=20; Trypanoso... 88 1e-16 UniRef50_Q5CS07 Cluster: Malic enzyme; n=2; Cryptosporidium|Rep:... 88 2e-16 UniRef50_Q5KBK5 Cluster: Nad-dependent malic enzyme, putative; n... 87 2e-16 UniRef50_A1SVL3 Cluster: Malic enzyme aka malate dehydrogenase (... 87 3e-16 UniRef50_Q7SHJ8 Cluster: Malic enzyme; n=12; Pezizomycotina|Rep:... 86 6e-16 UniRef50_A5C6I9 Cluster: Malic enzyme; n=1; Vitis vinifera|Rep: ... 85 8e-16 UniRef50_A4SKB8 Cluster: NAD-dependent malic enzyme; n=2; Aeromo... 82 8e-15 UniRef50_P45868 Cluster: Probable NAD-dependent malic enzyme 2; ... 82 1e-14 UniRef50_Q95061 Cluster: Malic enzyme; n=2; Giardia intestinalis... 80 4e-14 UniRef50_A6XP71 Cluster: Malic enzyme protein 2; n=2; Mucoromyco... 79 7e-14 UniRef50_Q7K3R0 Cluster: Malic enzyme; n=2; Sophophora|Rep: Mali... 79 1e-13 UniRef50_A3YYQ0 Cluster: Malate oxidoreductase; n=1; Synechococc... 78 1e-13 UniRef50_A2QY66 Cluster: Malic enzyme; n=2; cellular organisms|R... 78 2e-13 UniRef50_Q6AL43 Cluster: Related to NAD-dependent malic enzyme; ... 76 5e-13 UniRef50_Q5KEY3 Cluster: Malic enzyme; n=1; Filobasidiella neofo... 75 1e-12 UniRef50_P36013 Cluster: NAD-dependent malic enzyme, mitochondri... 75 1e-12 UniRef50_Q8Y5Y8 Cluster: Lmo1915 protein; n=15; Firmicutes|Rep: ... 72 1e-11 UniRef50_P40375 Cluster: NAD-dependent malic enzyme; n=3; Schizo... 72 1e-11 UniRef50_Q48796 Cluster: Malolactic enzyme; n=49; Bacteria|Rep: ... 69 8e-11 UniRef50_Q2HCG7 Cluster: Malic enzyme; n=1; Chaetomium globosum|... 62 7e-09 UniRef50_Q8S484 Cluster: Putative NADP-dependent malic enzyme; n... 60 3e-08 UniRef50_Q4T5P0 Cluster: Malic enzyme; n=1; Tetraodon nigrovirid... 44 0.002 UniRef50_Q5C370 Cluster: Malic enzyme; n=1; Schistosoma japonicu... 41 0.024 UniRef50_Q9S4T5 Cluster: NAD-malate oxidoreductase homolog; n=15... 40 0.055 UniRef50_A0K1T3 Cluster: Allergen V5/Tpx-1 family protein precur... 35 1.6 UniRef50_Q1EI20 Cluster: Putative uncharacterized protein; n=2; ... 33 6.3 UniRef50_Q5SLE4 Cluster: CBS domain protein; n=7; Bacteria|Rep: ... 33 6.3 UniRef50_A3XN08 Cluster: Putative uncharacterized protein; n=1; ... 33 6.3 UniRef50_UPI0000EBCB21 Cluster: PREDICTED: similar to FELE-2, pa... 32 8.3 UniRef50_Q4S3L6 Cluster: Chromosome 1 SCAF14749, whole genome sh... 32 8.3 UniRef50_Q8A0A0 Cluster: Putative outer membrane protein, probab... 32 8.3 UniRef50_A7E6G7 Cluster: Putative uncharacterized protein; n=1; ... 32 8.3 >UniRef50_A7T6B8 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 365 Score = 145 bits (351), Expect = 7e-34 Identities = 61/88 (69%), Positives = 77/88 (87%) Frame = +1 Query: 1 LDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLK 180 L+RNE LF+R + D E+MPIVYTPTVGLAC+K+G+++RRPRGLFI+IHDKGH+ D++ Sbjct: 79 LERNESLFFRVLFDYTEELMPIVYTPTVGLACRKYGMIFRRPRGLFISIHDKGHIRDIVS 138 Query: 181 NWPDTDVRAIVVTDGERILGLGDLGHAG 264 NWP T+V+AIV+TDGERILGLGDLG G Sbjct: 139 NWPTTEVKAIVMTDGERILGLGDLGCCG 166 Score = 110 bits (265), Expect = 2e-23 Identities = 48/74 (64%), Positives = 57/74 (77%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG C MGIPVGKLALYT GGI P CLP+ IDVGTN + +LDDP YIG+RQ+R DY Sbjct: 162 LGCCGMGIPVGKLALYTVCGGIDPEGCLPVMIDVGTNNEELLDDPFYIGVRQKRCNTEDY 221 Query: 429 DELLDEFMLAVVRR 470 DEL+DEF+ A ++R Sbjct: 222 DELIDEFIQAALQR 235 >UniRef50_Q4S0L0 Cluster: Malic enzyme; n=2; Tetraodon nigroviridis|Rep: Malic enzyme - Tetraodon nigroviridis (Green puffer) Length = 694 Score = 141 bits (342), Expect = 9e-33 Identities = 59/87 (67%), Positives = 74/87 (85%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 183 DRNE LFYR + ++ + MPIVYTPTVGLACQ++GL +RRPRGLFITIHD+GH+ +L + Sbjct: 127 DRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYGLAFRRPRGLFITIHDRGHIATMLNS 186 Query: 184 WPDTDVRAIVVTDGERILGLGDLGHAG 264 WP+ D++A+VVTDGERILGLGDLG G Sbjct: 187 WPEEDIKAVVVTDGERILGLGDLGSYG 213 Score = 90.6 bits (215), Expect = 2e-17 Identities = 49/96 (51%), Positives = 60/96 (62%), Gaps = 10/96 (10%) Frame = +3 Query: 249 LGACWMGIPVGKLALY-----TALGGIKPHQC-----LPITIDVGTNTQSILDDPLYIGL 398 LG+ MGIPVGKLAL A + P P ++ G Q +LDDPLYIGL Sbjct: 209 LGSYGMGIPVGKLALLHRLRRRAAAAVPPGAAGRGHRQPGSVPGGVCVQVLLDDPLYIGL 268 Query: 399 RQRRVRGPDYDELLDEFMLAVVRRYGQNCLVQFEDF 506 + +RVRG DYD L++EFM AV +YG NCL+QFEDF Sbjct: 269 KHKRVRGKDYDGLIEEFMQAVTDKYGMNCLIQFEDF 304 Score = 47.6 bits (108), Expect = 2e-04 Identities = 18/22 (81%), Positives = 21/22 (95%) Frame = +2 Query: 509 NANAFRLLQKYRNKYCTFNDDI 574 N+NAFR+L KYRN+YCTFNDDI Sbjct: 306 NSNAFRILNKYRNRYCTFNDDI 327 >UniRef50_Q16798 Cluster: NADP-dependent malic enzyme, mitochondrial precursor; n=15; Bilateria|Rep: NADP-dependent malic enzyme, mitochondrial precursor - Homo sapiens (Human) Length = 604 Score = 138 bits (335), Expect = 6e-32 Identities = 60/87 (68%), Positives = 73/87 (83%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 183 DRNE LFYR + +V + MPIVYTPTVGLACQ +GL +RRPRGLFITIHDKGH+ +L + Sbjct: 115 DRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNS 174 Query: 184 WPDTDVRAIVVTDGERILGLGDLGHAG 264 WP+ +++A+VVTDGERILGLGDLG G Sbjct: 175 WPEDNIKAVVVTDGERILGLGDLGCYG 201 Score = 130 bits (314), Expect = 2e-29 Identities = 57/86 (66%), Positives = 68/86 (79%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG MGIPVGKLALYTA GG+ P QCLP+ +DVGTN + +L DPLYIGL+ +RV G Y Sbjct: 197 LGCYGMGIPVGKLALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVHGKAY 256 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 D+LLDEFM AV ++G NCL+QFEDF Sbjct: 257 DDLLDEFMQAVTDKFGINCLIQFEDF 282 Score = 48.4 bits (110), Expect = 1e-04 Identities = 20/22 (90%), Positives = 20/22 (90%) Frame = +2 Query: 509 NANAFRLLQKYRNKYCTFNDDI 574 NANAFRLL KYRNKYC FNDDI Sbjct: 284 NANAFRLLNKYRNKYCMFNDDI 305 >UniRef50_P06801 Cluster: NADP-dependent malic enzyme; n=52; cellular organisms|Rep: NADP-dependent malic enzyme - Mus musculus (Mouse) Length = 572 Score = 138 bits (333), Expect = 1e-31 Identities = 61/86 (70%), Positives = 68/86 (79%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG MGIPVGKLALYTA GG+ P QCLPIT+DVGT + +L DPLYIGLR RRVRGP+Y Sbjct: 162 LGCNGMGIPVGKLALYTACGGVNPQQCLPITLDVGTENEELLKDPLYIGLRHRRVRGPEY 221 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 D LDEFM A +YG NCL+QFEDF Sbjct: 222 DAFLDEFMEAASSKYGMNCLIQFEDF 247 Score = 132 bits (318), Expect = 7e-30 Identities = 59/87 (67%), Positives = 70/87 (80%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 183 DRNE LFY + +V + MPIVYTPTVGLACQ++ L +R+PRGLFI+IHDKGH+ VL Sbjct: 80 DRNEKLFYSVLMSDVEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDKGHIASVLNA 139 Query: 184 WPDTDVRAIVVTDGERILGLGDLGHAG 264 WP+ V+AIVVTDGERILGLGDLG G Sbjct: 140 WPEDVVKAIVVTDGERILGLGDLGCNG 166 Score = 48.8 bits (111), Expect = 9e-05 Identities = 20/22 (90%), Positives = 20/22 (90%) Frame = +2 Query: 509 NANAFRLLQKYRNKYCTFNDDI 574 N NAFRLL KYRNKYCTFNDDI Sbjct: 249 NRNAFRLLNKYRNKYCTFNDDI 270 >UniRef50_P48163 Cluster: NADP-dependent malic enzyme; n=63; Eukaryota|Rep: NADP-dependent malic enzyme - Homo sapiens (Human) Length = 572 Score = 136 bits (328), Expect = 5e-31 Identities = 59/87 (67%), Positives = 72/87 (82%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 183 DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+GH+ VL Sbjct: 80 DRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASVLNA 139 Query: 184 WPDTDVRAIVVTDGERILGLGDLGHAG 264 WP+ ++AIVVTDGERILGLGDLG G Sbjct: 140 WPEDVIKAIVVTDGERILGLGDLGCNG 166 Score = 134 bits (325), Expect = 1e-30 Identities = 59/86 (68%), Positives = 69/86 (80%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG MGIPVGKLALYTA GG+ P +CLP+ +DVGT + +L DPLYIGLRQRRVRG +Y Sbjct: 162 LGCNGMGIPVGKLALYTACGGMNPQECLPVILDVGTENEELLKDPLYIGLRQRRVRGSEY 221 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 D+ LDEFM AV +YG NCL+QFEDF Sbjct: 222 DDFLDEFMEAVSSKYGMNCLIQFEDF 247 Score = 47.6 bits (108), Expect = 2e-04 Identities = 19/22 (86%), Positives = 20/22 (90%) Frame = +2 Query: 509 NANAFRLLQKYRNKYCTFNDDI 574 N NAFRLL KYRN+YCTFNDDI Sbjct: 249 NVNAFRLLNKYRNQYCTFNDDI 270 >UniRef50_Q5BX10 Cluster: Malic enzyme; n=1; Schistosoma japonicum|Rep: Malic enzyme - Schistosoma japonicum (Blood fluke) Length = 216 Score = 135 bits (326), Expect = 8e-31 Identities = 58/94 (61%), Positives = 75/94 (79%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 183 DRNE LFY+ V ++V MP++YTPTVGLACQ++G+V+RRPRGL+ITIHD+ H+ ++L N Sbjct: 119 DRNEALFYKLVIEHVEYCMPLIYTPTVGLACQRYGVVFRRPRGLYITIHDRHHIPEILNN 178 Query: 184 WPDTDVRAIVVTDGERILGLGDLGHAGWASLLAN 285 WP+ V+AIV TDGERILGLGDLG G + N Sbjct: 179 WPEPIVKAIVFTDGERILGLGDLGAYGMGIPIGN 212 >UniRef50_A2ZQ54 Cluster: Malic enzyme; n=9; Oryza sativa|Rep: Malic enzyme - Oryza sativa subsp. japonica (Rice) Length = 613 Score = 132 bits (320), Expect = 4e-30 Identities = 54/87 (62%), Positives = 74/87 (85%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 183 +RNE LFY+ + DNV E++P+VYTPTVG ACQK+G ++R+P+GL++++ DKG V DVL+N Sbjct: 165 ERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFRQPQGLYVSLKDKGKVLDVLRN 224 Query: 184 WPDTDVRAIVVTDGERILGLGDLGHAG 264 WP+ +++ IVVTDGERILGLGDLG G Sbjct: 225 WPERNIQVIVVTDGERILGLGDLGCQG 251 Score = 124 bits (300), Expect = 1e-27 Identities = 56/86 (65%), Positives = 68/86 (79%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG MGIPVGKL+LYTALGG++P CLPITIDVGTN + +L+D YIGLRQRR G +Y Sbjct: 247 LGCQGMGIPVGKLSLYTALGGVRPSACLPITIDVGTNNEQLLNDEFYIGLRQRRATGKEY 306 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 EL++EFM AV + YG+ L+QFEDF Sbjct: 307 HELMEEFMSAVKQIYGEKVLIQFEDF 332 >UniRef50_P23368 Cluster: NAD-dependent malic enzyme, mitochondrial precursor; n=53; Eumetazoa|Rep: NAD-dependent malic enzyme, mitochondrial precursor - Homo sapiens (Human) Length = 584 Score = 132 bits (318), Expect = 7e-30 Identities = 55/87 (63%), Positives = 72/87 (82%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 183 +RNE LFYR + D++ +MPIVYTPTVGLAC ++G ++RRP+GLFI+I D+GHV ++ N Sbjct: 90 ERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIVDN 149 Query: 184 WPDTDVRAIVVTDGERILGLGDLGHAG 264 WP+ V+A+VVTDGERILGLGDLG G Sbjct: 150 WPENHVKAVVVTDGERILGLGDLGVYG 176 Score = 117 bits (281), Expect = 2e-25 Identities = 52/86 (60%), Positives = 65/86 (75%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG MGIPVGKL LYTA GI+P +CLP+ IDVGT+ ++L DP Y+GL Q+R R Y Sbjct: 172 LGVYGMGIPVGKLCLYTACAGIRPDRCLPVCIDVGTDNIALLKDPFYMGLYQKRDRTQQY 231 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 D+L+DEFM A+ RYG+N L+QFEDF Sbjct: 232 DDLIDEFMKAITDRYGRNTLIQFEDF 257 Score = 44.8 bits (101), Expect = 0.001 Identities = 18/22 (81%), Positives = 19/22 (86%) Frame = +2 Query: 509 NANAFRLLQKYRNKYCTFNDDI 574 N NAFR L+KYR KYCTFNDDI Sbjct: 259 NHNAFRFLRKYREKYCTFNDDI 280 >UniRef50_Q89G76 Cluster: Malic enzyme; n=3; cellular organisms|Rep: Malic enzyme - Bradyrhizobium japonicum Length = 531 Score = 130 bits (313), Expect = 3e-29 Identities = 57/87 (65%), Positives = 71/87 (81%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 183 DRNE LF+R V DN+ E+ PI+YTPTVGLACQK+GL+++RPRG+FI+ D+G + ++LKN Sbjct: 65 DRNEALFFRVVVDNIDEIQPIIYTPTVGLACQKYGLIFQRPRGMFISSRDRGQIAEILKN 124 Query: 184 WPDTDVRAIVVTDGERILGLGDLGHAG 264 WP R IVVTDGERILGLGDLG G Sbjct: 125 WP-YPARLIVVTDGERILGLGDLGANG 150 Score = 108 bits (259), Expect = 1e-22 Identities = 49/86 (56%), Positives = 63/86 (73%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LGA MGIPVGKL+LY+A G+ P CLPI +DVGTN + +L+DP Y+GLR+RR+ G Y Sbjct: 146 LGANGMGIPVGKLSLYSACAGVHPEHCLPIVLDVGTNNEELLNDPYYLGLRERRLTGEAY 205 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 D +DEFM+A R+ L+QFEDF Sbjct: 206 DSFVDEFMVA-ARKTFPGVLIQFEDF 230 Score = 35.9 bits (79), Expect = 0.68 Identities = 14/22 (63%), Positives = 18/22 (81%) Frame = +2 Query: 509 NANAFRLLQKYRNKYCTFNDDI 574 N +AF+LL KYR++ C FNDDI Sbjct: 232 NHSAFKLLHKYRDEACVFNDDI 253 >UniRef50_A0L5P5 Cluster: Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)); n=1; Magnetococcus sp. MC-1|Rep: Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)) - Magnetococcus sp. (strain MC-1) Length = 556 Score = 126 bits (304), Expect = 4e-28 Identities = 55/87 (63%), Positives = 69/87 (79%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 183 +RNE LFYR V N+ EM+PI+YTPTVG ACQ +G ++RRP+G+FI+I+DKG + ++L N Sbjct: 84 ERNETLFYRLVMTNIEEMLPIIYTPTVGKACQTYGHIFRRPQGMFISINDKGRIAELLGN 143 Query: 184 WPDTDVRAIVVTDGERILGLGDLGHAG 264 W DVR IVVTDG RILGLGDLG G Sbjct: 144 WVHKDVRVIVVTDGSRILGLGDLGAHG 170 Score = 111 bits (268), Expect = 8e-24 Identities = 51/86 (59%), Positives = 67/86 (77%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LGA MGIPVGKLALYTAL GI P CLP+T+D+GTN +++ +DPLY+GL Q RV G Y Sbjct: 166 LGAHGMGIPVGKLALYTALAGIPPIHCLPVTLDMGTNNEALRNDPLYVGLPQPRVTGEIY 225 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 DE+++EF+LAV ++ ++QFEDF Sbjct: 226 DEMIEEFVLAVQEQF-PRAMIQFEDF 250 Score = 41.1 bits (92), Expect = 0.018 Identities = 16/22 (72%), Positives = 20/22 (90%) Frame = +2 Query: 509 NANAFRLLQKYRNKYCTFNDDI 574 N NAFRLL+KY+++ CTFNDDI Sbjct: 252 NDNAFRLLEKYQDRICTFNDDI 273 >UniRef50_A7CWP9 Cluster: Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)); n=1; Opitutaceae bacterium TAV2|Rep: Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)) - Opitutaceae bacterium TAV2 Length = 561 Score = 125 bits (302), Expect = 6e-28 Identities = 55/86 (63%), Positives = 70/86 (81%) Frame = +1 Query: 7 RNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNW 186 RNE LFYR + ++ EM+P+VYTPTVG AC ++G +RRPRGLFI+I D+G + ++L++W Sbjct: 90 RNETLFYRLLTNHAEEMIPLVYTPTVGQACLEYGANFRRPRGLFISIKDRGRIAEILRHW 149 Query: 187 PDTDVRAIVVTDGERILGLGDLGHAG 264 P TDVR IVVTDGERILGLGDLG G Sbjct: 150 PITDVRMIVVTDGERILGLGDLGVLG 175 Score = 93.5 bits (222), Expect = 3e-18 Identities = 43/86 (50%), Positives = 60/86 (69%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG MGIPVGKLALY+A G+ P CLPI +D G + +++ +DPLY+G +RVRG DY Sbjct: 171 LGVLGMGIPVGKLALYSACAGLHPSYCLPIALDAGIDNETLRNDPLYLGHPMKRVRGADY 230 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 D L+EF+ AV + + ++Q+EDF Sbjct: 231 DAFLNEFVEAVKTVFPKT-MIQWEDF 255 Score = 35.9 bits (79), Expect = 0.68 Identities = 14/22 (63%), Positives = 18/22 (81%) Frame = +2 Query: 509 NANAFRLLQKYRNKYCTFNDDI 574 N NAFRLL + R++ C+FNDDI Sbjct: 257 NTNAFRLLHENRSRVCSFNDDI 278 >UniRef50_P16243 Cluster: NADP-dependent malic enzyme, chloroplast precursor; n=79; Magnoliophyta|Rep: NADP-dependent malic enzyme, chloroplast precursor - Zea mays (Maize) Length = 636 Score = 125 bits (301), Expect = 9e-28 Identities = 57/86 (66%), Positives = 68/86 (79%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG MGIPVGKLALYTALGG+ P CLPITIDVGTN + +L+D YIGLRQ+R G +Y Sbjct: 244 LGCQGMGIPVGKLALYTALGGVDPSVCLPITIDVGTNNEFLLNDEFYIGLRQKRATGEEY 303 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 DEL++EFM AV + YG+ L+QFEDF Sbjct: 304 DELIEEFMSAVKQFYGEKVLIQFEDF 329 Score = 121 bits (292), Expect = 1e-26 Identities = 50/87 (57%), Positives = 69/87 (79%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 183 + +E LFY+ + DNV E++P VYTPTVG ACQK+G ++ RP+GL++++ DKG V +VL+N Sbjct: 162 ETDERLFYKLLIDNVVELLPFVYTPTVGEACQKYGSIFGRPQGLYVSLKDKGKVLEVLRN 221 Query: 184 WPDTDVRAIVVTDGERILGLGDLGHAG 264 WP +++ I VTDGERILGLGDLG G Sbjct: 222 WPHRNIQVICVTDGERILGLGDLGCQG 248 >UniRef50_Q0AIF8 Cluster: Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)); n=2; Nitrosomonas|Rep: Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)) - Nitrosomonas eutropha (strain C71) Length = 536 Score = 124 bits (298), Expect = 2e-27 Identities = 53/88 (60%), Positives = 69/88 (78%) Frame = +1 Query: 1 LDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLK 180 L+RN+ LFYR + D++ E+MP+VYTPTVG AC K ++R+P+G +IT D+G + LK Sbjct: 70 LERNQQLFYRTLVDHIGEIMPLVYTPTVGEACVKLSHIFRKPQGFYITPEDRGEIISRLK 129 Query: 181 NWPDTDVRAIVVTDGERILGLGDLGHAG 264 NWP+TDV+ IVVTDGERILGLGDLG G Sbjct: 130 NWPETDVQIIVVTDGERILGLGDLGANG 157 Score = 97.9 bits (233), Expect = 1e-19 Identities = 45/86 (52%), Positives = 61/86 (70%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LGA MGIP+GK++LY A GI P +C+P+ +DVGT Q++ +DPLY+G R+ G DY Sbjct: 153 LGANGMGIPIGKISLYVACAGIYPDRCMPVMLDVGTGNQALREDPLYLGYPYPRLVGQDY 212 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 L+DEF+ AV RY + L+QFEDF Sbjct: 213 LSLVDEFVEAVQHRY-PDALIQFEDF 237 >UniRef50_A7PC00 Cluster: Chromosome chr2 scaffold_11, whole genome shotgun sequence; n=3; Vitis vinifera|Rep: Chromosome chr2 scaffold_11, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 573 Score = 120 bits (289), Expect = 2e-26 Identities = 51/87 (58%), Positives = 68/87 (78%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 183 +RNE LFY+ + DNV E++P+VYTPTVG ACQK+G ++RRP+ L+I G + +VLKN Sbjct: 262 ERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFRRPQSLYIIDFFMGKILEVLKN 321 Query: 184 WPDTDVRAIVVTDGERILGLGDLGHAG 264 WP+ ++ IVVT+GERILGLGDLG G Sbjct: 322 WPERSIQVIVVTNGERILGLGDLGCQG 348 Score = 93.5 bits (222), Expect = 3e-18 Identities = 42/68 (61%), Positives = 50/68 (73%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG MGIPVGKL+LYT LGG+ P CLP+TIDVGTN + +L D YIGL+QRR G +Y Sbjct: 344 LGCQGMGIPVGKLSLYTTLGGLHPSVCLPVTIDVGTNNEQLLKDEFYIGLKQRRATGQEY 403 Query: 429 DELLDEFM 452 ELL E + Sbjct: 404 AELLHELI 411 >UniRef50_Q016K2 Cluster: NADP dependent malic enzyme; n=2; Ostreococcus|Rep: NADP dependent malic enzyme - Ostreococcus tauri Length = 641 Score = 114 bits (274), Expect = 2e-24 Identities = 46/95 (48%), Positives = 73/95 (76%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 183 +RNE LFYR V D++ E++P++ PTV C++ GL+YR+PRGL++++ DKG VY +LKN Sbjct: 148 ERNERLFYRVVKDHLEELLPVLAEPTVWQVCREAGLMYRQPRGLYVSMQDKGSVYRLLKN 207 Query: 184 WPDTDVRAIVVTDGERILGLGDLGHAGWASLLANS 288 WP +V+A+V+TDG+R+ G+GDLG G + ++ + Sbjct: 208 WPVRNVKAVVLTDGQRVTGIGDLGVQGMPAAVSKA 242 Score = 93.9 bits (223), Expect = 2e-18 Identities = 46/91 (50%), Positives = 61/91 (67%) Frame = +3 Query: 234 SGSWRLGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRV 413 +G LG M V K +L+TALGG+ P LPI IDVGT+ Q++L+D YIGLRQ+RV Sbjct: 225 TGIGDLGVQGMPAAVSKASLFTALGGLDPADVLPICIDVGTDNQTLLEDKFYIGLRQKRV 284 Query: 414 RGPDYDELLDEFMLAVVRRYGQNCLVQFEDF 506 G Y+ELLDE + + RR+G L+ FE+F Sbjct: 285 GGEAYEELLDEVVSGLKRRFGPRVLLCFEEF 315 >UniRef50_A3QW96 Cluster: Malic enzyme; n=10; Tigriopus californicus|Rep: Malic enzyme - Tigriopus californicus (Marine copepod) Length = 322 Score = 111 bits (268), Expect = 8e-24 Identities = 48/87 (55%), Positives = 62/87 (71%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 183 DRNE LFYR + DN +M PI+YTPTVG AC F +YRRPRG++ + D+G + ++ N Sbjct: 129 DRNETLFYRILMDNFQDMAPIIYTPTVGWACSHFSQLYRRPRGMYFSHGDRGEMASMVYN 188 Query: 184 WPDTDVRAIVVTDGERILGLGDLGHAG 264 W +V A+V+TDG RILGLGDLG G Sbjct: 189 WESDEVDAVVITDGSRILGLGDLGLGG 215 Score = 88.2 bits (209), Expect = 1e-16 Identities = 40/86 (46%), Positives = 56/86 (65%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG +GI +GKL LY A GG P + LP+ +D+GTN Q +L+DP Y+GL+Q R+ G +Y Sbjct: 211 LGLGGLGISIGKLDLYVAAGGFHPRRVLPVVLDIGTNNQKLLNDPNYLGLKQPRIDGEEY 270 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 ++DE M A R+ L+Q EDF Sbjct: 271 YAIMDELMAATKLRW-PRALIQHEDF 295 >UniRef50_P37221 Cluster: NAD-dependent malic enzyme 62 kDa isoform, mitochondrial precursor; n=41; Eukaryota|Rep: NAD-dependent malic enzyme 62 kDa isoform, mitochondrial precursor - Solanum tuberosum (Potato) Length = 626 Score = 111 bits (268), Expect = 8e-24 Identities = 48/87 (55%), Positives = 63/87 (72%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 183 DRNE L+Y+ + +N+ E PIVYTPTVGL CQK+ ++RRPRG++ + D+G + ++ N Sbjct: 124 DRNETLYYKVLMENIEEYAPIVYTPTVGLVCQKYSGLFRRPRGMYFSAEDRGEMMSMVYN 183 Query: 184 WPDTDVRAIVVTDGERILGLGDLGHAG 264 WP V IVVTDG RILGLGDLG G Sbjct: 184 WPADQVDMIVVTDGSRILGLGDLGIQG 210 Score = 93.5 bits (222), Expect = 3e-18 Identities = 44/86 (51%), Positives = 61/86 (70%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG +GI +GKL LY A GI P + LP+ IDVGT+ +++L DPLY+GL+ R+ G +Y Sbjct: 206 LGIQGIGIAIGKLDLYVAAAGINPQRVLPVMIDVGTDNENLLKDPLYLGLQDHRLDGEEY 265 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 E++DEFM AV R+ + +VQFEDF Sbjct: 266 IEVIDEFMEAVFTRW-PHVIVQFEDF 290 Score = 34.7 bits (76), Expect = 1.6 Identities = 14/19 (73%), Positives = 16/19 (84%) Frame = +2 Query: 518 AFRLLQKYRNKYCTFNDDI 574 AF+LLQ+YRN Y FNDDI Sbjct: 295 AFKLLQRYRNNYRMFNDDI 313 >UniRef50_Q8D911 Cluster: NAD-dependent malic enzyme; n=187; cellular organisms|Rep: NAD-dependent malic enzyme - Vibrio vulnificus Length = 562 Score = 109 bits (263), Expect = 3e-23 Identities = 49/87 (56%), Positives = 64/87 (73%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 183 D NE LFYR V +++ EMMPI+YTPTVG AC+ F +YRR RGLF++ ++ + D+L N Sbjct: 79 DTNETLFYRLVQNHITEMMPIIYTPTVGAACENFSNIYRRGRGLFVSYANRDRIDDILNN 138 Query: 184 WPDTDVRAIVVTDGERILGLGDLGHAG 264 + +V+ IVVTDGERILGLGD G G Sbjct: 139 ASNHNVKVIVVTDGERILGLGDQGIGG 165 Score = 99.1 bits (236), Expect = 6e-20 Identities = 46/81 (56%), Positives = 58/81 (71%) Frame = +3 Query: 264 MGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDYDELLD 443 MGIP+GKL+LYTA GGI P LPI +DVGTN L DP+Y+G R R+ G DYD ++ Sbjct: 166 MGIPIGKLSLYTACGGISPAYTLPIVLDVGTNNPQRLADPMYMGWRHPRITGADYDAFVE 225 Query: 444 EFMLAVVRRYGQNCLVQFEDF 506 EF+ AV RR+ + L+QFEDF Sbjct: 226 EFIQAVQRRW-PDALIQFEDF 245 Score = 33.1 bits (72), Expect = 4.8 Identities = 12/20 (60%), Positives = 16/20 (80%) Frame = +2 Query: 515 NAFRLLQKYRNKYCTFNDDI 574 NA LL++Y+N+ C FNDDI Sbjct: 249 NAMPLLERYKNRICCFNDDI 268 >UniRef50_A1ZAF7 Cluster: Malic enzyme; n=5; Sophophora|Rep: Malic enzyme - Drosophila melanogaster (Fruit fly) Length = 603 Score = 109 bits (261), Expect = 6e-23 Identities = 47/86 (54%), Positives = 64/86 (74%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 +GA MGI +GK+ LYTALG I P +P+ +DVGT+ Q++L DPLY+G R RV+GP+Y Sbjct: 185 MGANAMGISLGKMILYTALGSIPPSTLMPVCLDVGTDNQALLQDPLYVGARIPRVKGPEY 244 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 DEL+DEFM + V+ +G N + FEDF Sbjct: 245 DELVDEFMESAVKCFGNNTFIHFEDF 270 Score = 105 bits (252), Expect = 7e-22 Identities = 44/83 (53%), Positives = 62/83 (74%) Frame = +1 Query: 7 RNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNW 186 R+ L+YRF+ +N+ + +PIVYTPTVG +GL +++ LFI+IHDKGH+ D++ NW Sbjct: 104 RHRRLYYRFIKENIEKSLPIVYTPTVGDVVATYGLNFQQAISLFISIHDKGHIRDLMHNW 163 Query: 187 PDTDVRAIVVTDGERILGLGDLG 255 D V+AI VTDG R+LGLGD+G Sbjct: 164 VDEGVKAICVTDGGRVLGLGDMG 186 Score = 35.1 bits (77), Expect = 1.2 Identities = 13/20 (65%), Positives = 16/20 (80%) Frame = +2 Query: 515 NAFRLLQKYRNKYCTFNDDI 574 NA + L+KY+ KYC FNDDI Sbjct: 274 NALKFLEKYQYKYCCFNDDI 293 >UniRef50_Q86NT5 Cluster: Malic enzyme; n=2; Drosophila melanogaster|Rep: Malic enzyme - Drosophila melanogaster (Fruit fly) Length = 610 Score = 108 bits (259), Expect = 1e-22 Identities = 48/85 (56%), Positives = 64/85 (75%), Gaps = 1/85 (1%) Frame = +1 Query: 13 EHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWP- 189 E L+++FV+ NV ++PI+YTPTVGLAC +G++YR G+ IT HD+GH+ +L NWP Sbjct: 114 ERLYFQFVSKNVHAVLPIIYTPTVGLACTVYGMLYRGMTGIHITKHDRGHMKQILSNWPM 173 Query: 190 DTDVRAIVVTDGERILGLGDLGHAG 264 V+AI VTDG+RILGLGDLG G Sbjct: 174 RRSVKAICVTDGQRILGLGDLGANG 198 Score = 105 bits (253), Expect = 6e-22 Identities = 52/99 (52%), Positives = 64/99 (64%) Frame = +3 Query: 210 CCNRRRTYSGSWRLGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLY 389 C + G LGA MGI VGK+ LYTAL GI P LPI +DVGTN +S+ +DPLY Sbjct: 181 CVTDGQRILGLGDLGANGMGIAVGKMELYTALAGIPPSMLLPICLDVGTNNKSLHEDPLY 240 Query: 390 IGLRQRRVRGPDYDELLDEFMLAVVRRYGQNCLVQFEDF 506 IGLR R++G +Y +DEFM AVV +G L+ FEDF Sbjct: 241 IGLRDERLKGDEYVCFVDEFMEAVVSTFGDQTLIHFEDF 279 >UniRef50_A6SA55 Cluster: Malic enzyme; n=2; Sclerotiniaceae|Rep: Malic enzyme - Botryotinia fuckeliana B05.10 Length = 685 Score = 107 bits (257), Expect = 2e-22 Identities = 44/87 (50%), Positives = 65/87 (74%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 183 + N HLFYR V +++ ++ P++YTPTVG AC ++ +Y++P GL+++ HD+G++ +VL N Sbjct: 155 NNNVHLFYRLVQEHLTDITPLIYTPTVGEACLRWSEIYQQPEGLYLSYHDRGNLEEVLGN 214 Query: 184 WPDTDVRAIVVTDGERILGLGDLGHAG 264 W +DV VVTDG RILGLGDLG G Sbjct: 215 WRQSDVEMTVVTDGSRILGLGDLGVNG 241 Score = 88.2 bits (209), Expect = 1e-16 Identities = 42/86 (48%), Positives = 58/86 (67%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG MGIPVGKL+LYT GI P + LPIT+D+GTN + L DPLY+G R +RV + Sbjct: 237 LGVNGMGIPVGKLSLYTGCAGIHPSKTLPITLDLGTNNEKFLKDPLYMGNRMKRVSTKEE 296 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 E ++E M+A+ + + +VQ+EDF Sbjct: 297 AEFMEELMVALNKMW-PGIIVQYEDF 321 >UniRef50_Q8I8I4 Cluster: Malic enzyme; n=4; Eukaryota|Rep: Malic enzyme - Mastigamoeba balamuthi (Phreatamoeba balamuthi) Length = 568 Score = 106 bits (255), Expect = 3e-22 Identities = 50/86 (58%), Positives = 61/86 (70%) Frame = +1 Query: 7 RNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNW 186 RN+ LF+ V +V E +P+VYTPTVG C KF +R P GL+IT DKGHV ++L+NW Sbjct: 101 RNQTLFFYLVQHHVEECVPLVYTPTVGEGCTKFSAEFRNPTGLYITPEDKGHVAEILENW 160 Query: 187 PDTDVRAIVVTDGERILGLGDLGHAG 264 P +V IVVTDG RILGLGDLG G Sbjct: 161 PH-EVEIIVVTDGGRILGLGDLGSNG 185 Score = 100 bits (240), Expect = 2e-20 Identities = 48/86 (55%), Positives = 61/86 (70%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG+ MGIP+GKL LY A G +P + LP+ IDVGTN Q +LDDP+Y+G+R+ R+ +Y Sbjct: 181 LGSNGMGIPIGKLHLYIACAGFRPDRTLPVMIDVGTNRQELLDDPMYLGVRKARLGDAEY 240 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 LL+EFM A VR CLVQFEDF Sbjct: 241 FALLEEFMTA-VRAKWPRCLVQFEDF 265 >UniRef50_A3BK03 Cluster: Malic enzyme; n=2; Oryza sativa|Rep: Malic enzyme - Oryza sativa subsp. japonica (Rice) Length = 635 Score = 104 bits (250), Expect = 1e-21 Identities = 47/89 (52%), Positives = 62/89 (69%), Gaps = 2/89 (2%) Frame = +1 Query: 4 DRNEHLFYR--FVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVL 177 DRNE ++Y+ + DN+ E PIVYTPTVGL CQ + ++RRPRG++ + D+G + ++ Sbjct: 156 DRNETMYYKAEVLIDNIEEHAPIVYTPTVGLVCQNYSGLFRRPRGMYFSAEDRGEMMSMV 215 Query: 178 KNWPDTDVRAIVVTDGERILGLGDLGHAG 264 NWP V IVVTDG RILGLGDLG G Sbjct: 216 YNWPADQVDMIVVTDGSRILGLGDLGVHG 244 Score = 97.1 bits (231), Expect = 3e-19 Identities = 45/86 (52%), Positives = 60/86 (69%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG +GI +GKL LY A GI P + LP+ IDVGTN + +L DPLY+GL++ R+ G +Y Sbjct: 240 LGVHGIGIAIGKLDLYVAAAGINPQRVLPVMIDVGTNNEKLLKDPLYLGLQEHRLEGEEY 299 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 ++DEFM AV R+ N +VQFEDF Sbjct: 300 VAIIDEFMEAVFARW-PNVIVQFEDF 324 Score = 32.7 bits (71), Expect = 6.3 Identities = 13/19 (68%), Positives = 15/19 (78%) Frame = +2 Query: 518 AFRLLQKYRNKYCTFNDDI 574 AFRLLQ+YR Y FNDD+ Sbjct: 329 AFRLLQRYRKTYRMFNDDV 347 >UniRef50_P78715 Cluster: Malic enzyme, hydrogenosomal precursor; n=1; Neocallimastix frontalis|Rep: Malic enzyme, hydrogenosomal precursor - Neocallimastix frontalis (Rumen fungus) Length = 592 Score = 104 bits (249), Expect = 2e-21 Identities = 45/87 (51%), Positives = 60/87 (68%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 183 +RNE L+Y+ + +N E+ PI+YTP VG ACQKF ++ + RG++ + D+G + V N Sbjct: 112 NRNETLYYKMILENFVELAPIIYTPVVGEACQKFHKIFTQTRGMYFSTADRGQMSAVAAN 171 Query: 184 WPDTDVRAIVVTDGERILGLGDLGHAG 264 WP DV IVVTDG RILGLGDLG G Sbjct: 172 WPYDDVDVIVVTDGSRILGLGDLGAGG 198 Score = 90.6 bits (215), Expect = 2e-17 Identities = 40/86 (46%), Positives = 59/86 (68%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LGA M IP+GKL LY GGI P LPI +DVGTN + +L+DPLY+G++ R++G ++ Sbjct: 194 LGAGGMQIPIGKLTLYVCGGGINPRNVLPIVLDVGTNNKELLNDPLYLGMQHPRLQGEEF 253 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 +DE++ A+ R+ ++QFEDF Sbjct: 254 HAFVDEWVSAITDRF-PKAVIQFEDF 278 >UniRef50_Q4X1Z2 Cluster: NADP-dependent malic enzyme MaeA; n=11; Pezizomycotina|Rep: NADP-dependent malic enzyme MaeA - Aspergillus fumigatus (Sartorya fumigata) Length = 661 Score = 103 bits (248), Expect = 2e-21 Identities = 42/85 (49%), Positives = 61/85 (71%) Frame = +1 Query: 10 NEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWP 189 N HLFYR V D++ E+ P++YTP VG ACQK+ +Y++P G++++ D+G++ V+ NWP Sbjct: 149 NVHLFYRLVTDHLKELTPLIYTPVVGEACQKWSEIYQQPEGMYLSWEDRGNLAAVIANWP 208 Query: 190 DTDVRAIVVTDGERILGLGDLGHAG 264 +V +TDG RILGLGDLG G Sbjct: 209 QPNVEITCITDGSRILGLGDLGING 233 Score = 89.8 bits (213), Expect = 4e-17 Identities = 40/86 (46%), Positives = 60/86 (69%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG MGIP+GKLALYTA GI+P LP+T+D+GT+ +++ +DPLY+G R+ ++ + Sbjct: 229 LGINGMGIPIGKLALYTACAGIRPEATLPLTLDLGTSNKALREDPLYMGTRRDKISPEEE 288 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 E +DE M A+ R+ ++QFEDF Sbjct: 289 REFMDELMAALTERW-PGIVIQFEDF 313 >UniRef50_UPI0000D9F768 Cluster: PREDICTED: similar to Y48B6A.12, partial; n=1; Macaca mulatta|Rep: PREDICTED: similar to Y48B6A.12, partial - Macaca mulatta Length = 456 Score = 103 bits (247), Expect = 3e-21 Identities = 48/87 (55%), Positives = 62/87 (71%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 183 DRNE L+++ + D+VAEMMPIVYTP VG ACQ FG ++R RGL+ + +KG+ +++ N Sbjct: 72 DRNETLYFKLLVDHVAEMMPIVYTPVVGKACQLFGHIFRNARGLYFNLSEKGNFKEMVWN 131 Query: 184 WPDTDVRAIVVTDGERILGLGDLGHAG 264 D IVVTDG RILGLGDLG G Sbjct: 132 SNVRDADIIVVTDGSRILGLGDLGTNG 158 Score = 91.1 bits (216), Expect = 2e-17 Identities = 43/86 (50%), Positives = 59/86 (68%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG MGIP+GKL+LY A GI P + +P+T+DVGTN +L+D +Y+G R +RV G +Y Sbjct: 154 LGTNGMGIPIGKLSLYVACAGINPGRTVPVTLDVGTNNPDLLNDDMYLGERHKRVDGEEY 213 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 +DEF+ AV R+ L+QFEDF Sbjct: 214 YAAVDEFVDAVRSRW-PGVLIQFEDF 238 >UniRef50_A7IMB8 Cluster: Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)); n=2; Alphaproteobacteria|Rep: Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)) - Xanthobacter sp. (strain Py2) Length = 550 Score = 103 bits (247), Expect = 3e-21 Identities = 45/86 (52%), Positives = 61/86 (70%) Frame = +1 Query: 7 RNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNW 186 RNE +FY+ V + +PI+Y PTV AC+ FG +YRRPRG++IT H KG + +VL+NW Sbjct: 85 RNETVFYKAVMSDPKRFIPILYDPTVADACEAFGNLYRRPRGMYITRHMKGRMAEVLRNW 144 Query: 187 PDTDVRAIVVTDGERILGLGDLGHAG 264 P D+R + V+ G RILGLGD+G G Sbjct: 145 PQKDIRFVCVSTGGRILGLGDIGANG 170 Score = 78.2 bits (184), Expect = 1e-13 Identities = 37/86 (43%), Positives = 52/86 (60%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 +GA MGIP+GKL LYTA + P LP+ D+GT+ + + DP Y+G R+ V + Sbjct: 166 IGANGMGIPIGKLQLYTACAAVPPDVLLPVLFDIGTSNEHLRADPFYLGTREAPVSEAEL 225 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 DEL +EF+ AV + C V FED+ Sbjct: 226 DELTEEFVQAVNEVF-PGCCVHFEDW 250 >UniRef50_Q01AM5 Cluster: NADP+-dependent malic enzyme; n=2; Ostreococcus|Rep: NADP+-dependent malic enzyme - Ostreococcus tauri Length = 580 Score = 103 bits (246), Expect = 4e-21 Identities = 44/85 (51%), Positives = 61/85 (71%) Frame = +1 Query: 10 NEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWP 189 +E FYR + ++PI+YTPTVG AC KFG + +RP GL+++ +D G+V +++NWP Sbjct: 113 DESTFYRMLRSQTETLLPILYTPTVGEACVKFGTLVQRPMGLWVSSNDAGNVKQLIRNWP 172 Query: 190 DTDVRAIVVTDGERILGLGDLGHAG 264 TDV+ V+TDGERILGLGD G G Sbjct: 173 ATDVKIAVITDGERILGLGDQGANG 197 Score = 95.9 bits (228), Expect = 6e-19 Identities = 46/85 (54%), Positives = 58/85 (68%) Frame = +3 Query: 252 GACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDYD 431 GA MGI GK +Y A G + P LPI +D GTN Q++LDDPLYIGL+Q+R R YD Sbjct: 194 GANGMGISAGKSMVYAACG-VPPSALLPIQVDTGTNNQTLLDDPLYIGLKQKRDRTKAYD 252 Query: 432 ELLDEFMLAVVRRYGQNCLVQFEDF 506 LLDE ++AV RYGQ ++ +EDF Sbjct: 253 ALLDEIVVAVRSRYGQKTIIHWEDF 277 >UniRef50_A4RZU1 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic enzyme - Ostreococcus lucimarinus CCE9901 Length = 539 Score = 102 bits (245), Expect = 5e-21 Identities = 48/86 (55%), Positives = 60/86 (69%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LGA MGI GK+ LYT G++P CLP+ +DVGTN Q +LDDP Y GLR+ R++G Y Sbjct: 141 LGAGGMGISEGKILLYTVCAGVRPSACLPVCLDVGTNNQRLLDDPNYKGLRRTRLKGEAY 200 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 D L+DEFM +R + CLVQFEDF Sbjct: 201 DALVDEFM-REMRAWQPRCLVQFEDF 225 Score = 48.8 bits (111), Expect(2) = 3e-10 Identities = 22/48 (45%), Positives = 29/48 (60%) Frame = +1 Query: 22 FYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHV 165 FYR + E+MP VYTPTVG AC+K+ + G++IT D G V Sbjct: 35 FYRALVREPLELMPFVYTPTVGEACEKYHRLGIETNGVYITADDAGRV 82 Score = 38.3 bits (85), Expect(2) = 3e-10 Identities = 18/25 (72%), Positives = 18/25 (72%) Frame = +1 Query: 190 DTDVRAIVVTDGERILGLGDLGHAG 264 D V VVTDGERILGLGDLG G Sbjct: 121 DDGVAVAVVTDGERILGLGDLGAGG 145 Score = 34.7 bits (76), Expect = 1.6 Identities = 15/22 (68%), Positives = 17/22 (77%) Frame = +2 Query: 509 NANAFRLLQKYRNKYCTFNDDI 574 NANAFR+L+KYR FNDDI Sbjct: 227 NANAFRILEKYRTTGPCFNDDI 248 >UniRef50_Q00XN9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic enzyme - Ostreococcus tauri Length = 639 Score = 101 bits (243), Expect = 9e-21 Identities = 47/87 (54%), Positives = 60/87 (68%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 183 DRNE LFYR V D++ E+ PI+YTPTVG AC F + RR RG++ ++ D+G + ++ N Sbjct: 146 DRNETLFYRLVHDHIEELAPIIYTPTVGDACLNFSKLLRRARGMYFSVDDRGDINSMMFN 205 Query: 184 WPDTDVRAIVVTDGERILGLGDLGHAG 264 W V IVVTDG RILGLGDLG G Sbjct: 206 W-KRSVSVIVVTDGSRILGLGDLGTNG 231 Score = 85.8 bits (203), Expect = 6e-16 Identities = 39/86 (45%), Positives = 56/86 (65%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG MGI GK+ LY A GG P LP+ +DVGTN + +L+DP Y+G+ ++R+ G +Y Sbjct: 227 LGTNGMGISQGKVDLYVAGGGFDPQHVLPVVLDVGTNNEDLLNDPYYLGVPRKRLEGEEY 286 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 ++EF+ V R+ N L+QFEDF Sbjct: 287 YAFIEEFIRGVRNRW-PNALIQFEDF 311 >UniRef50_Q4PC56 Cluster: Malic enzyme; n=1; Ustilago maydis|Rep: Malic enzyme - Ustilago maydis (Smut fungus) Length = 634 Score = 100 bits (239), Expect = 3e-20 Identities = 45/87 (51%), Positives = 59/87 (67%), Gaps = 2/87 (2%) Frame = +1 Query: 10 NEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNW- 186 N L+Y + N E++P++YTPTVG ACQKF +YRRP GL I++ DKG + +++NW Sbjct: 144 NTRLYYATILANKEEILPLIYTPTVGEACQKFSHIYRRPEGLSISLEDKGKIASIVENWP 203 Query: 187 -PDTDVRAIVVTDGERILGLGDLGHAG 264 P R V+TDG RILGLGDLG G Sbjct: 204 VPAGSPRIAVITDGSRILGLGDLGWNG 230 Score = 87.8 bits (208), Expect = 2e-16 Identities = 43/86 (50%), Positives = 56/86 (65%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG GI +GKL+LY A GI P LPI +D+GTN + L+DPLY+GLR+ R +Y Sbjct: 226 LGWNGQGISIGKLSLYVAGAGIHPRATLPIVVDLGTNNKKNLEDPLYLGLRRERASTEEY 285 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 E +DE M A+ RY N ++QFEDF Sbjct: 286 IEFMDEVMHALHTRY-PNLIIQFEDF 310 Score = 33.5 bits (73), Expect = 3.6 Identities = 13/20 (65%), Positives = 16/20 (80%) Frame = +2 Query: 515 NAFRLLQKYRNKYCTFNDDI 574 NAFR L++Y+ KY FNDDI Sbjct: 314 NAFRFLERYQGKYPMFNDDI 333 >UniRef50_A2EKE3 Cluster: Malic enzyme; n=14; Trichomonadidae|Rep: Malic enzyme - Trichomonas vaginalis G3 Length = 567 Score = 98.7 bits (235), Expect = 8e-20 Identities = 46/86 (53%), Positives = 60/86 (69%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LGA +GIPVGKL LYT +G + P Q LP+ +D+GT+ + IL DPLY G R RVRG ++ Sbjct: 172 LGASGLGIPVGKLMLYTLIGQVDPDQTLPVQLDMGTDRKEILADPLYHGWRHPRVRGAEH 231 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 + + EF+ AV +G CLVQFEDF Sbjct: 232 LKFVTEFVEAVKEVFGDTCLVQFEDF 257 Score = 94.7 bits (225), Expect = 1e-18 Identities = 45/88 (51%), Positives = 61/88 (69%), Gaps = 1/88 (1%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAE-MMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLK 180 ++N F+RF+ + E MPI+YTPTVG ACQK+ + RG++IT D G + D+L+ Sbjct: 89 EKNSQSFWRFLFTHPPEETMPILYTPTVGEACQKWATHRQSYRGIYITPEDSGKIKDILR 148 Query: 181 NWPDTDVRAIVVTDGERILGLGDLGHAG 264 N+P D+R IVVTD RILGLGDLG +G Sbjct: 149 NYPRQDIRCIVVTDAGRILGLGDLGASG 176 >UniRef50_Q875H8 Cluster: Malic enzyme; n=1; Mucor circinelloides|Rep: Malic enzyme - Mucor circinelloides Length = 617 Score = 98.3 bits (234), Expect = 1e-19 Identities = 43/87 (49%), Positives = 60/87 (68%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 183 DRNE L+Y+ + +++ E+ I+YTPTVGLA Q +YRR RG++ + D+G + ++ N Sbjct: 115 DRNETLYYKIIMEHLEELAGIIYTPTVGLASQMSHSIYRRSRGMYFSSQDRGQMSAMVYN 174 Query: 184 WPDTDVRAIVVTDGERILGLGDLGHAG 264 WP V IVVTDG R+LGLGDLG G Sbjct: 175 WPHDKVDVIVVTDGSRVLGLGDLGANG 201 Score = 97.5 bits (232), Expect = 2e-19 Identities = 43/86 (50%), Positives = 61/86 (70%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LGA M IP+GKL+LY A GGI+P LP+ +DVGTN Q +L+DPLY+G+ R+ G +Y Sbjct: 197 LGANGMEIPIGKLSLYVAAGGIRPRAVLPVVLDVGTNNQDLLNDPLYLGMSHPRLEGEEY 256 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 +DE++ A+ R+ + L+QFEDF Sbjct: 257 YSFIDEWVTAITSRW-PDTLIQFEDF 281 >UniRef50_A4RQC9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic enzyme - Ostreococcus lucimarinus CCE9901 Length = 549 Score = 96.7 bits (230), Expect = 3e-19 Identities = 44/88 (50%), Positives = 59/88 (67%) Frame = +1 Query: 7 RNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNW 186 +NE LFYR + +++ ++MPIVYTPTVG AC F +YR G++ + D G + +L NW Sbjct: 75 QNERLFYRVLVEHLEDLMPIVYTPTVGEACINFDALYRNRCGMYFSRLDSGVMRRMLDNW 134 Query: 187 PDTDVRAIVVTDGERILGLGDLGHAGWA 270 P + IVVTDG R+LGLGDLG G A Sbjct: 135 PSPETEIIVVTDGGRVLGLGDLGTNGMA 162 Score = 70.1 bits (164), Expect = 3e-11 Identities = 34/86 (39%), Positives = 53/86 (61%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG M I VGK++LY A GG P + +P+ +D+GT+ ++ Y+G + R+ G + Sbjct: 156 LGTNGMAISVGKVSLYVASGGFDPAKSMPVCLDLGTSNVALRAHDFYLGADEPRLTGDAH 215 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 ++ EF LAV ++ NCL+QFEDF Sbjct: 216 LAVVTEFCLAVKDKW-PNCLIQFEDF 240 >UniRef50_Q9HE50 Cluster: Malic enzyme; n=6; Pezizomycotina|Rep: Malic enzyme - Neurospora crassa Length = 1023 Score = 95.9 bits (228), Expect = 6e-19 Identities = 42/86 (48%), Positives = 56/86 (65%) Frame = +1 Query: 7 RNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNW 186 +N LFYR + D+ EMMP+VYTPT+G C ++ +Y RP L+I+I + + +L+NW Sbjct: 538 QNVDLFYRLLMDHAKEMMPLVYTPTIGDVCLQYSTLYTRPEALYISIKQRKSIRTILRNW 597 Query: 187 PDTDVRAIVVTDGERILGLGDLGHAG 264 P VVTDG RILGLGDLG G Sbjct: 598 PYPQPEICVVTDGSRILGLGDLGVNG 623 Score = 90.6 bits (215), Expect = 2e-17 Identities = 44/86 (51%), Positives = 58/86 (67%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG +GIP+GKLALYTA GI P + LPI +D GT ++ L DPLY+GLRQ+R+ + Sbjct: 619 LGVNGVGIPIGKLALYTAAAGIHPDKTLPIVLDCGTANETNLKDPLYLGLRQKRIPVAEQ 678 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 E +DEFM A + + +VQFEDF Sbjct: 679 QEFMDEFMEAAAEVF-PDMVVQFEDF 703 >UniRef50_A0Q531 Cluster: NAD-dependent malic enzyme; n=10; Francisella tularensis|Rep: NAD-dependent malic enzyme - Francisella tularensis subsp. novicida (strain U112) Length = 604 Score = 92.3 bits (219), Expect = 7e-18 Identities = 41/87 (47%), Positives = 58/87 (66%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 183 D N LFY FV +N+ E+MPI+YTPTVG A QK+ +R+ GLFI+I K H+ +L+ Sbjct: 92 DLNTTLFYHFVRENLEEIMPIIYTPTVGEAVQKYSSSFRKQSGLFISISHKKHIARILER 151 Query: 184 WPDTDVRAIVVTDGERILGLGDLGHAG 264 + + ++VTDGE +LG+GD G G Sbjct: 152 YEYNSIDLVLVTDGEAVLGIGDQGIGG 178 Score = 73.3 bits (172), Expect = 4e-12 Identities = 33/80 (41%), Positives = 51/80 (63%) Frame = +3 Query: 264 MGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDYDELLD 443 M I +GK+ +Y A GI P + LP+ +D+GTN ++L+ P Y+G+R RV G YDE ++ Sbjct: 179 MNISIGKIMVYVAASGIDPARVLPVQLDMGTNNDALLNAPGYLGVRLPRVSGETYDEFIE 238 Query: 444 EFMLAVVRRYGQNCLVQFED 503 EF+ V R+ N + +ED Sbjct: 239 EFVTQVKARF-PNVFLHWED 257 Score = 37.1 bits (82), Expect = 0.29 Identities = 14/20 (70%), Positives = 18/20 (90%) Frame = +2 Query: 515 NAFRLLQKYRNKYCTFNDDI 574 NA R+L+KY++K CTFNDDI Sbjct: 262 NATRILEKYKDKLCTFNDDI 281 >UniRef50_Q9RYN4 Cluster: Malate oxidoreductase; n=6; Deinococci|Rep: Malate oxidoreductase - Deinococcus radiodurans Length = 580 Score = 91.9 bits (218), Expect = 1e-17 Identities = 46/89 (51%), Positives = 55/89 (61%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 183 DRNE LFY ++ +V EM+PIVYTPTVG A +KF +YR PRGL ++ L N Sbjct: 102 DRNEVLFYALLSHHVEEMLPIVYTPTVGDAVKKFSQIYRYPRGLTLSTRTIERAEQALAN 161 Query: 184 WPDTDVRAIVVTDGERILGLGDLGHAGWA 270 P DVR IV TD ILG+GD G G A Sbjct: 162 VPLNDVRIIVATDSSAILGIGDQGFGGMA 190 Score = 80.2 bits (189), Expect = 3e-14 Identities = 33/81 (40%), Positives = 54/81 (66%) Frame = +3 Query: 264 MGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDYDELLD 443 M I +GKL+LYT GG+ P + LP+ +DVGT + +DP Y+G++ R+ G +Y +D Sbjct: 189 MAISIGKLSLYTVAGGVGPDKTLPVELDVGTGRADLREDPHYLGVKHERLTGEEYFAFID 248 Query: 444 EFMLAVVRRYGQNCLVQFEDF 506 +F+ A ++RY ++Q+EDF Sbjct: 249 KFVEATIQRY-PKAIIQWEDF 268 >UniRef50_Q5K758 Cluster: Malic enzyme; n=1; Filobasidiella neoformans|Rep: Malic enzyme - Cryptococcus neoformans (Filobasidiella neoformans) Length = 600 Score = 89.0 bits (211), Expect = 7e-17 Identities = 42/86 (48%), Positives = 56/86 (65%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG MGI VGKL LY A GG+ PH CLP+ +D+GTN +++ +DPLYIGL+Q RV + Sbjct: 201 LGIGGMGISVGKLNLYVAGGGVNPHGCLPVVLDMGTNNEAVRNDPLYIGLKQPRVGLEEA 260 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 E +D FM A + ++Q EDF Sbjct: 261 TEFMDAFMAAASEAF-PKAVIQHEDF 285 Score = 87.0 bits (206), Expect = 3e-16 Identities = 41/86 (47%), Positives = 56/86 (65%), Gaps = 3/86 (3%) Frame = +1 Query: 16 HLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPDT 195 +LF+ + D + E+ PIVYTPTVG ACQK+ +Y P GL++ I DK + ++L + Sbjct: 120 NLFFSVMRDELTELAPIVYTPTVGEACQKYSQIYSGPEGLYLNIEDKDRIPEILHQYASK 179 Query: 196 DV---RAIVVTDGERILGLGDLGHAG 264 V + +VVTDG RILGLGDLG G Sbjct: 180 LVAPPQILVVTDGSRILGLGDLGIGG 205 >UniRef50_Q4QAQ6 Cluster: Malic enzyme, putative; n=20; Trypanosomatidae|Rep: Malic enzyme, putative - Leishmania major Length = 573 Score = 88.2 bits (209), Expect = 1e-16 Identities = 39/85 (45%), Positives = 58/85 (68%) Frame = +1 Query: 10 NEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWP 189 N L+Y + + + +PIVYTPTVG ACQ++G +Y++ GL++ + KG V +++N Sbjct: 86 NVTLYYAILTRYLKQTLPIVYTPTVGEACQRYGDLYQKDHGLYLDVASKGKVRRLIQNLR 145 Query: 190 DTDVRAIVVTDGERILGLGDLGHAG 264 T++ IV+TDG RILGLGDLG G Sbjct: 146 KTNIDVIVITDGSRILGLGDLGSNG 170 Score = 86.6 bits (205), Expect = 4e-16 Identities = 42/86 (48%), Positives = 59/86 (68%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG+ +GI +GK +LY A GG+KP + LP+ +DVGTN + ++PLY+GLR+ R D+ Sbjct: 166 LGSNGIGISIGKCSLYVAAGGVKPSRVLPVVMDVGTNNLELRNNPLYLGLRKPRCGDADF 225 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 LLDEFM AV + + +VQFEDF Sbjct: 226 YALLDEFMEAVKDTW-PSAVVQFEDF 250 >UniRef50_Q5CS07 Cluster: Malic enzyme; n=2; Cryptosporidium|Rep: Malic enzyme - Cryptosporidium parvum Iowa II Length = 614 Score = 87.8 bits (208), Expect = 2e-16 Identities = 40/85 (47%), Positives = 59/85 (69%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG MGIP+GKL+LY LGGI P + LPI++D+GTNT IL D Y+G+ ++R+ +Y Sbjct: 217 LGLNGMGIPMGKLSLYITLGGIDPSKVLPISLDIGTNTNDILSDKYYLGICEKRIDNDEY 276 Query: 429 DELLDEFMLAVVRRYGQNCLVQFED 503 L+DE A+ +R+ N ++Q+ED Sbjct: 277 FPLMDEITKAIFKRW-PNTVLQWED 300 Score = 68.9 bits (161), Expect = 8e-11 Identities = 36/86 (41%), Positives = 51/86 (59%), Gaps = 4/86 (4%) Frame = +1 Query: 19 LFYRFVADNVAEMMPIVYTPTVGLACQKFGL--VYRR--PRGLFITIHDKGHVYDVLKNW 186 LF+ + ++ P+VYTPTVG C +F R GL++ KG +Y++LK++ Sbjct: 136 LFHSLLDKYFKDLTPLVYTPTVGEGCIEFSRNPTIRNWLGSGLYLNKSHKGRIYEILKDF 195 Query: 187 PDTDVRAIVVTDGERILGLGDLGHAG 264 D+ IV+TDG RILGLGDLG G Sbjct: 196 KSDDIEIIVLTDGGRILGLGDLGLNG 221 >UniRef50_Q5KBK5 Cluster: Nad-dependent malic enzyme, putative; n=2; Filobasidiella neoformans|Rep: Nad-dependent malic enzyme, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 584 Score = 87.4 bits (207), Expect = 2e-16 Identities = 37/84 (44%), Positives = 59/84 (70%) Frame = +3 Query: 252 GACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDYD 431 G+ +GI K +Y+ + G+ P +CL IT+DVGTN Q +L+DPLYIG R++R+R YD Sbjct: 177 GSGGIGISGAKAVIYSLIAGVDPAKCLAITLDVGTNNQDLLNDPLYIGYREKRLRDDRYD 236 Query: 432 ELLDEFMLAVVRRYGQNCLVQFED 503 + +D+F + +V+++ CL+ FED Sbjct: 237 QFVDKF-VGLVKKHQPECLLHFED 259 Score = 64.1 bits (149), Expect = 2e-09 Identities = 35/87 (40%), Positives = 49/87 (56%), Gaps = 1/87 (1%) Frame = +1 Query: 7 RNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFIT-IHDKGHVYDVLKN 183 +N LFY + ++ EM PIVYTPT A + ++RR GL++T +K D L Sbjct: 94 QNWTLFYALLQAHLVEMFPIVYTPTEADAIADYSHLFRRSEGLYLTPPGEKNMEEDFLDA 153 Query: 184 WPDTDVRAIVVTDGERILGLGDLGHAG 264 ++ IVV+DGE ILG+GD G G Sbjct: 154 CEGRELELIVVSDGEAILGIGDQGSGG 180 >UniRef50_A1SVL3 Cluster: Malic enzyme aka malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)); n=4; Gammaproteobacteria|Rep: Malic enzyme aka malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)) - Psychromonas ingrahamii (strain 37) Length = 571 Score = 87.0 bits (206), Expect = 3e-16 Identities = 40/87 (45%), Positives = 57/87 (65%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 183 DRNE LFY ++ N+ EM PI+YTPTVG ACQ+F ++ RGL++T + V + + Sbjct: 89 DRNETLFYALISRNIEEMTPIIYTPTVGKACQEFSHRFQIARGLYLTTDNIHDVGSMARE 148 Query: 184 WPDTDVRAIVVTDGERILGLGDLGHAG 264 + D++ IVVTD + ILG+GD G G Sbjct: 149 FTGKDIQIIVVTDSQGILGIGDQGVGG 175 Score = 80.2 bits (189), Expect = 3e-14 Identities = 35/85 (41%), Positives = 55/85 (64%) Frame = +3 Query: 252 GACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDYD 431 G MGIP+GKL+LYT GI P C+PI +D+GT+ Q +L DP+Y+G+ ++R+ G Y Sbjct: 172 GVGGMGIPIGKLSLYTLGAGIHPDHCMPIALDIGTDNQDLLADPMYLGIPKKRLTGEPYK 231 Query: 432 ELLDEFMLAVVRRYGQNCLVQFEDF 506 + F + V+ + ++Q+EDF Sbjct: 232 AFIKTF-VEQVKLHFPKAVLQWEDF 255 >UniRef50_Q7SHJ8 Cluster: Malic enzyme; n=12; Pezizomycotina|Rep: Malic enzyme - Neurospora crassa Length = 611 Score = 85.8 bits (203), Expect = 6e-16 Identities = 42/88 (47%), Positives = 56/88 (63%), Gaps = 1/88 (1%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 183 ++NE LFYR + D++ EM +VYTPT G A Q + ++RRP G+F+ I+D V L Sbjct: 100 EQNEVLFYRLLHDHLDEMFSVVYTPTEGEAIQNYSRLFRRPEGVFLNINDMDSVKRDLAQ 159 Query: 184 W-PDTDVRAIVVTDGERILGLGDLGHAG 264 W D+ IVVTDGE ILG+GD G G Sbjct: 160 WGKPEDIDYIVVTDGEEILGIGDQGCGG 187 Score = 78.2 bits (184), Expect = 1e-13 Identities = 35/79 (44%), Positives = 49/79 (62%) Frame = +3 Query: 270 IPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDYDELLDEF 449 I + KL L T GGI P++ LP+ +D GTN + +L D LY+GLRQ+R RG YD+ ++ F Sbjct: 190 ISIAKLVLMTICGGIHPNRVLPVVLDCGTNNEELLKDDLYLGLRQKRARGDKYDDFVETF 249 Query: 450 MLAVVRRYGQNCLVQFEDF 506 + A Y + FEDF Sbjct: 250 IKAARELY-PRAYIHFEDF 267 >UniRef50_A5C6I9 Cluster: Malic enzyme; n=1; Vitis vinifera|Rep: Malic enzyme - Vitis vinifera (Grape) Length = 498 Score = 85.4 bits (202), Expect = 8e-16 Identities = 41/86 (47%), Positives = 56/86 (65%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG +GIP+GKL +Y A GI P + LPI +DVGTN Q +L+D LY+GLRQ R+ G +Y Sbjct: 58 LGVQGIGIPIGKLDMYVAAAGINPQRILPIMLDVGTNNQRLLEDRLYLGLRQPRLEGEEY 117 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 ++DE M A+ R+ +VQ F Sbjct: 118 LSVVDELMEAIFTRW-PKAIVQVHFF 142 Score = 37.9 bits (84), Expect = 0.17 Identities = 19/42 (45%), Positives = 25/42 (59%) Frame = +1 Query: 139 ITIHDKGHVYDVLKNWPDTDVRAIVVTDGERILGLGDLGHAG 264 IT + H++ + + V IV+TDG RILGLGDLG G Sbjct: 21 ITXNGIXHIWSDIGSXDLCQVDMIVITDGSRILGLGDLGVQG 62 Score = 34.7 bits (76), Expect = 1.6 Identities = 13/19 (68%), Positives = 15/19 (78%) Frame = +2 Query: 518 AFRLLQKYRNKYCTFNDDI 574 AF LQ+YR K+C FNDDI Sbjct: 176 AFETLQRYRKKFCMFNDDI 194 >UniRef50_A4SKB8 Cluster: NAD-dependent malic enzyme; n=2; Aeromonas|Rep: NAD-dependent malic enzyme - Aeromonas salmonicida (strain A449) Length = 516 Score = 82.2 bits (194), Expect = 8e-15 Identities = 40/86 (46%), Positives = 56/86 (65%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG MGI +GKLALY+A GGI P + LP+ +DVGTN +L+D Y+G + RV G Y Sbjct: 141 LGIGGMGICIGKLALYSAAGGINPARTLPLCVDVGTNNPELLEDDSYLGWQANRVDGESY 200 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 +D+ + A+ R+ Q ++QFEDF Sbjct: 201 YHFMDKVVAAIRTRWPQ-VVLQFEDF 225 Score = 80.6 bits (190), Expect = 2e-14 Identities = 38/85 (44%), Positives = 56/85 (65%) Frame = +1 Query: 10 NEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWP 189 N LFY V ++ E++PI+YTP VG ACQ+ +Y R GL+++ HD+ + D + Sbjct: 62 NPVLFYDLVRHHLPELLPIIYTPVVGEACQRHSDLYLRSHGLYLSWHDRDDL-DAIFAAV 120 Query: 190 DTDVRAIVVTDGERILGLGDLGHAG 264 + +V IV++DGER+LGLGDLG G Sbjct: 121 EQEVDVIVISDGERVLGLGDLGIGG 145 >UniRef50_P45868 Cluster: Probable NAD-dependent malic enzyme 2; n=37; Bacteria|Rep: Probable NAD-dependent malic enzyme 2 - Bacillus subtilis Length = 582 Score = 81.8 bits (193), Expect = 1e-14 Identities = 39/89 (43%), Positives = 59/89 (66%), Gaps = 2/89 (2%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 183 +RNE LFY+ + +++ EM+P+VYTPTVG A Q++ YRRP+G++++I + + +N Sbjct: 100 NRNEVLFYKLLKNHLREMLPVVYTPTVGEAIQEYSHEYRRPQGIYLSIDNIDGIEKAFEN 159 Query: 184 WPDT--DVRAIVVTDGERILGLGDLGHAG 264 T D+ IV TD E ILG+GD G G Sbjct: 160 LHATAGDIDLIVATDSESILGIGDWGVGG 188 Score = 81.0 bits (191), Expect = 2e-14 Identities = 36/89 (40%), Positives = 58/89 (65%) Frame = +3 Query: 237 GSWRLGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVR 416 G W +G + I +GKLA+YTA GI P + +P+ +DVGTN + +L+DPLYIG + RV+ Sbjct: 182 GDWGVGG--INIAIGKLAVYTAAAGIDPSRVIPVVLDVGTNNEKLLNDPLYIGNKHERVQ 239 Query: 417 GPDYDELLDEFMLAVVRRYGQNCLVQFED 503 G Y+ +D ++ A + ++ L+ +ED Sbjct: 240 GERYEAFIDAYVKAAL-KFFPKALLHWED 267 >UniRef50_Q95061 Cluster: Malic enzyme; n=2; Giardia intestinalis|Rep: Malic enzyme - Giardia lamblia (Giardia intestinalis) Length = 557 Score = 79.8 bits (188), Expect = 4e-14 Identities = 41/86 (47%), Positives = 52/86 (60%), Gaps = 1/86 (1%) Frame = +1 Query: 10 NEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYR-RPRGLFITIHDKGHVYDVLKNW 186 NE LF F + E++PIVYTPTVG AC + L+++ PRG ++ G V + W Sbjct: 72 NETLFSGFCLKYLKEVLPIVYTPTVGTACSNYSLLWQGYPRGFYLNRTHLGKVKQIFDQW 131 Query: 187 PDTDVRAIVVTDGERILGLGDLGHAG 264 P + R IV TDG RILGLGDLG G Sbjct: 132 PYSP-RIIVATDGTRILGLGDLGTGG 156 Score = 67.3 bits (157), Expect = 2e-10 Identities = 35/86 (40%), Positives = 50/86 (58%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG I VGKL LY+ GG P LPI+ D G NT I +DP Y+G+ ++R + Y Sbjct: 152 LGTGGHQICVGKLTLYSLGGGFAPEHTLPISFDFGCNTDKIREDPHYLGIPEKRNKDDTY 211 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 ++ E + AV ++ +C+ QFEDF Sbjct: 212 YGIIKETIEAVHSKW-PDCIFQFEDF 236 >UniRef50_A6XP71 Cluster: Malic enzyme protein 2; n=2; Mucoromycotina|Rep: Malic enzyme protein 2 - Mortierella alpina (Mortierella renispora) Length = 669 Score = 79.0 bits (186), Expect = 7e-14 Identities = 40/86 (46%), Positives = 52/86 (60%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG MGIPVGKL LY A GI P + LPIT+D+GTN + L D Y+GLR++R + Sbjct: 256 LGVGGMGIPVGKLQLYVAGAGIDPRRTLPITLDLGTNNEDKLKDEFYLGLREKRAGDDKF 315 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 +D + A+ Y L+QFEDF Sbjct: 316 FPFVDAVIEALTSLY-PKLLIQFEDF 340 Score = 78.6 bits (185), Expect = 1e-13 Identities = 40/97 (41%), Positives = 58/97 (59%), Gaps = 12/97 (12%) Frame = +1 Query: 10 NEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVY------RRPRGLFITIHDKGHVYD 171 N LFY V D + E +P++YTPTVG ACQ + +Y +P GLF++I+D ++ Sbjct: 164 NVRLFYGLVGDQLEETLPLIYTPTVGTACQNYSSIYPFLAPPGQPDGLFLSINDLPNLTQ 223 Query: 172 VLKNW------PDTDVRAIVVTDGERILGLGDLGHAG 264 +++N+ P + V+TDG RILGLGDLG G Sbjct: 224 IIQNYKPFPQDPSLTPQIAVITDGSRILGLGDLGVGG 260 >UniRef50_Q7K3R0 Cluster: Malic enzyme; n=2; Sophophora|Rep: Malic enzyme - Drosophila melanogaster (Fruit fly) Length = 633 Score = 78.6 bits (185), Expect = 1e-13 Identities = 37/86 (43%), Positives = 52/86 (60%) Frame = +3 Query: 249 LGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDY 428 LG M I L GGI P CL + +DVGTN + +L+DP+Y GLR+RR Y Sbjct: 219 LGVDEMPILFSNLHQNVVYGGIHPAYCLAVMLDVGTNNEELLNDPMYTGLRERRCSEKLY 278 Query: 429 DELLDEFMLAVVRRYGQNCLVQFEDF 506 D+L +EF L+V+++YG L+ +DF Sbjct: 279 DQLFEEFTLSVMQQYGPRALILCKDF 304 Score = 57.6 bits (133), Expect = 2e-07 Identities = 28/83 (33%), Positives = 43/83 (51%) Frame = +1 Query: 7 RNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNW 186 RN LFY + N +P+ +++ +GL+I I D GHV +L NW Sbjct: 138 RNRRLFYYLLLSNPDRFVPMTDASGSIDLLMVHRMIHSMGQGLYICIKDLGHVSQILSNW 197 Query: 187 PDTDVRAIVVTDGERILGLGDLG 255 P VR ++V++G +L +GDLG Sbjct: 198 PFRCVRCLLVSNGASVLSVGDLG 220 >UniRef50_A3YYQ0 Cluster: Malate oxidoreductase; n=1; Synechococcus sp. WH 5701|Rep: Malate oxidoreductase - Synechococcus sp. WH 5701 Length = 517 Score = 78.2 bits (184), Expect = 1e-13 Identities = 40/86 (46%), Positives = 53/86 (61%), Gaps = 1/86 (1%) Frame = +1 Query: 10 NEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPR-GLFITIHDKGHVYDVLKNW 186 N LF+RF+AD++ +MPIVYTPTVG A Q+F L YR P G+F+ D + VL Sbjct: 35 NLTLFHRFLADHIEAVMPIVYTPTVGAAIQRFSLDYRTPSGGVFLAAPDLERIESVLSQA 94 Query: 187 PDTDVRAIVVTDGERILGLGDLGHAG 264 V I++TD + ILG+GD G G Sbjct: 95 ATGPVDLILITDSQGILGIGDQGIGG 120 Score = 66.9 bits (156), Expect = 3e-10 Identities = 33/79 (41%), Positives = 50/79 (63%) Frame = +3 Query: 270 IPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDYDELLDEF 449 I +GKLA+YT G+ P + LP+ +DVGT+ +L++PLY G R R+ G DYD L Sbjct: 123 ICLGKLAVYTLCAGLDPARVLPLVLDVGTDRVELLENPLYPGWRHPRLDGLDYDRFLARS 182 Query: 450 MLAVVRRYGQNCLVQFEDF 506 + A+ R++ L+ +EDF Sbjct: 183 VEALQRQF-PGALLHWEDF 200 >UniRef50_A2QY66 Cluster: Malic enzyme; n=2; cellular organisms|Rep: Malic enzyme - Aspergillus niger Length = 609 Score = 77.8 bits (183), Expect = 2e-13 Identities = 36/79 (45%), Positives = 52/79 (65%) Frame = +3 Query: 270 IPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDYDELLDEF 449 I V KLAL T GI P + LP+ +D GT+ +S+L D LY+GLRQ RVRG +YD+ +++F Sbjct: 212 ISVAKLALTTLCAGIHPSRQLPVVLDCGTDNESLLTDELYLGLRQSRVRGEEYDQFVEKF 271 Query: 450 MLAVVRRYGQNCLVQFEDF 506 + +R+ + FEDF Sbjct: 272 VETARKRF-PRAYIHFEDF 289 Score = 77.0 bits (181), Expect = 3e-13 Identities = 35/84 (41%), Positives = 55/84 (65%), Gaps = 1/84 (1%) Frame = +1 Query: 7 RNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNW 186 +NE L+Y+ + ++ EM+ I+YTPT G A Q + ++R+P G F+ I D+ + + L N+ Sbjct: 123 QNEVLYYKLIDTHLKEMLSIIYTPTEGDAIQNYSRLFRKPEGCFLNIRDQDRIEECLSNF 182 Query: 187 P-DTDVRAIVVTDGERILGLGDLG 255 +V IVV+DGE ILG+GD G Sbjct: 183 SRGEEVDYIVVSDGEEILGIGDQG 206 >UniRef50_Q6AL43 Cluster: Related to NAD-dependent malic enzyme; n=1; Desulfotalea psychrophila|Rep: Related to NAD-dependent malic enzyme - Desulfotalea psychrophila Length = 578 Score = 76.2 bits (179), Expect = 5e-13 Identities = 38/85 (44%), Positives = 53/85 (62%) Frame = +3 Query: 252 GACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDYD 431 GA + I +GKL LYT GI P CLPI++D+GT+ +++L D Y+G RQ+R+ G +Y Sbjct: 173 GAGGIAICLGKLMLYTQGAGIAPWHCLPISLDIGTDNEALLADKHYLGWRQKRLVGDEYT 232 Query: 432 ELLDEFMLAVVRRYGQNCLVQFEDF 506 +D F A R N L Q+EDF Sbjct: 233 AFIDRFARA-FRNVFPNALCQWEDF 256 Score = 74.1 bits (174), Expect = 2e-12 Identities = 36/92 (39%), Positives = 53/92 (57%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 183 DRN L + + ++ + M I+YTPTVGLA QK+ ++R+ GL + D+L+ Sbjct: 90 DRNVTLAHALIQSDLEKFMGIIYTPTVGLAVQKYSAMFRQANGLHFSPDTIDQAEDILRR 149 Query: 184 WPDTDVRAIVVTDGERILGLGDLGHAGWASLL 279 + D+R VVTD + ILG+GD G G A L Sbjct: 150 FAHRDIRVAVVTDNQGILGIGDQGAGGIAICL 181 >UniRef50_Q5KEY3 Cluster: Malic enzyme; n=1; Filobasidiella neoformans|Rep: Malic enzyme - Cryptococcus neoformans (Filobasidiella neoformans) Length = 629 Score = 74.9 bits (176), Expect = 1e-12 Identities = 32/79 (40%), Positives = 49/79 (62%) Frame = +3 Query: 270 IPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDYDELLDEF 449 I K ALYT GI P++ LP+ +D GT+ ++ DPLY+G ++ R+RG +YD+ +D F Sbjct: 222 ISTSKAALYTLGAGINPNRILPVVLDCGTDNHALFSDPLYMGWKRTRIRGKNYDQFIDRF 281 Query: 450 MLAVVRRYGQNCLVQFEDF 506 + R N ++ FEDF Sbjct: 282 -ITNCRELFPNAIIHFEDF 299 Score = 61.7 bits (143), Expect = 1e-08 Identities = 36/103 (34%), Positives = 56/103 (54%), Gaps = 16/103 (15%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHD--------KG 159 D+N+ LFYR + D + E++ ++YTP A + ++RRP G +I+ + +G Sbjct: 117 DQNQVLFYRLMQDRLKELLGVLYTPGAAEAVAGYSSLFRRPVGCYISFPNQDGMRAQLEG 176 Query: 160 HVYDVLK--------NWPDTDVRAIVVTDGERILGLGDLGHAG 264 H+ DV + N PD + +VVTD E ILG+GD G G Sbjct: 177 HLTDVNRTADVAYDSNKPDDAIDLVVVTDAEAILGIGDQGVGG 219 >UniRef50_P36013 Cluster: NAD-dependent malic enzyme, mitochondrial precursor; n=15; Saccharomycetales|Rep: NAD-dependent malic enzyme, mitochondrial precursor - Saccharomyces cerevisiae (Baker's yeast) Length = 669 Score = 74.9 bits (176), Expect = 1e-12 Identities = 35/79 (44%), Positives = 52/79 (65%) Frame = +3 Query: 270 IPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDYDELLDEF 449 I + KLAL T GGI P + LP+ +DVGTN + + D LY+G + R+RG YD+ L++F Sbjct: 255 IAISKLALMTLCGGIHPGRVLPVCLDVGTNNKKLARDELYMGNKFSRIRGKQYDDFLEKF 314 Query: 450 MLAVVRRYGQNCLVQFEDF 506 + AV + Y + ++ FEDF Sbjct: 315 IKAVKKVY-PSAVLHFEDF 332 Score = 63.7 bits (148), Expect = 3e-09 Identities = 32/87 (36%), Positives = 52/87 (59%), Gaps = 1/87 (1%) Frame = +1 Query: 7 RNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNW 186 +N+ L++ + ++ E++PI+YTPT G A + +R+P G+F+ I + + L + Sbjct: 166 QNKVLYFALIRRHIKELVPIIYTPTEGDAIAAYSHRFRKPEGVFLDITEPDSIECRLATY 225 Query: 187 -PDTDVRAIVVTDGERILGLGDLGHAG 264 D DV IVV+D E ILG+GD G G Sbjct: 226 GGDKDVDYIVVSDSEGILGIGDQGIGG 252 >UniRef50_Q8Y5Y8 Cluster: Lmo1915 protein; n=15; Firmicutes|Rep: Lmo1915 protein - Listeria monocytogenes Length = 547 Score = 71.7 bits (168), Expect = 1e-11 Identities = 33/90 (36%), Positives = 55/90 (61%) Frame = +3 Query: 237 GSWRLGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVR 416 G W + + I VGKLA+YT G+ P + LP+ ID GTN +++L+DPLY+G ++ R+ Sbjct: 154 GDWSVNG--VKIAVGKLAVYTVAAGLAPDRVLPVVIDAGTNNETLLNDPLYLGNKRPRLS 211 Query: 417 GPDYDELLDEFMLAVVRRYGQNCLVQFEDF 506 +YD + F + V++ ++ +EDF Sbjct: 212 ESEYDAFIASF-VNVMKEVFPKAILHWEDF 240 Score = 57.2 bits (132), Expect = 3e-07 Identities = 30/85 (35%), Positives = 48/85 (56%), Gaps = 3/85 (3%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRP-RGLFITIHDKGHVYDVLK 180 + N L+Y V NV + +PI+YTPT+G A ++ Y P LF+ + +K Sbjct: 71 NENRTLYYYVVTKNVTDYLPIIYTPTIGDAVIQYHKDYTAPDEALFVDAFAPEKLSASIK 130 Query: 181 NWP--DTDVRAIVVTDGERILGLGD 249 N+ + ++ IV+TDGE +LG+GD Sbjct: 131 NYAKNNPNIDMIVITDGEGVLGIGD 155 Score = 37.1 bits (82), Expect = 0.29 Identities = 15/21 (71%), Positives = 17/21 (80%) Frame = +2 Query: 512 ANAFRLLQKYRNKYCTFNDDI 574 ANA R+L YR+K CTFNDDI Sbjct: 243 ANASRILHNYRDKICTFNDDI 263 >UniRef50_P40375 Cluster: NAD-dependent malic enzyme; n=3; Schizosaccharomyces pombe|Rep: NAD-dependent malic enzyme - Schizosaccharomyces pombe (Fission yeast) Length = 565 Score = 71.7 bits (168), Expect = 1e-11 Identities = 35/88 (39%), Positives = 55/88 (62%), Gaps = 3/88 (3%) Frame = +1 Query: 10 NEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITI--HDKGHVYDVLKN 183 N+ LFY ++ ++ EM+PI+YTPT G A ++F +YR P G ++ I +D ++ L Sbjct: 83 NQTLFYALISQHLIEMIPIIYTPTEGDAIKQFSDIYRYPEGCYLDIDHNDLSYIKQQLSE 142 Query: 184 WPDTD-VRAIVVTDGERILGLGDLGHAG 264 + +D V I++TD E ILG+GD G G Sbjct: 143 FGKSDSVEYIIITDSEGILGIGDQGVGG 170 Score = 63.7 bits (148), Expect = 3e-09 Identities = 32/79 (40%), Positives = 45/79 (56%) Frame = +3 Query: 270 IPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVRGPDYDELLDEF 449 I V K L T G+ P++ LPI +DVGTN ++ + Y+GLR+ RVRG YD LD Sbjct: 173 ISVAKGHLMTLCAGLDPNRFLPIVLDVGTNNETHRKNHQYMGLRKDRVRGEQYDSFLDN- 231 Query: 450 MLAVVRRYGQNCLVQFEDF 506 ++ +R + FEDF Sbjct: 232 VIKAIREVFPEAFIHFEDF 250 >UniRef50_Q48796 Cluster: Malolactic enzyme; n=49; Bacteria|Rep: Malolactic enzyme - Oenococcus oeni (Leuconostoc oenos) Length = 541 Score = 68.9 bits (161), Expect = 8e-11 Identities = 35/90 (38%), Positives = 50/90 (55%) Frame = +3 Query: 237 GSWRLGACWMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVR 416 G W G + I VGKL +YT GI P L + ID GTN + +L DP+Y+G + RVR Sbjct: 151 GDW--GVQGVDIAVGKLMVYTVAAGIDPSTVLAVVIDAGTNNEKLLKDPMYLGNKFNRVR 208 Query: 417 GPDYDELLDEFMLAVVRRYGQNCLVQFEDF 506 G Y + +D+F+ + N + +EDF Sbjct: 209 GDKYYDFIDKFVNHAESLF-PNLYLHWEDF 237 Score = 63.7 bits (148), Expect = 3e-09 Identities = 32/87 (36%), Positives = 51/87 (58%), Gaps = 2/87 (2%) Frame = +1 Query: 10 NEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRG-LFITIHDKGHVYDVLKNW 186 N LFY+ + +V E MPIVY PT+ + + ++ P+G F+ I+ ++ LKN Sbjct: 71 NHVLFYKLFSQHVVEFMPIVYDPTIADTIENYSELFVEPQGAAFLDINHPENIQSTLKNA 130 Query: 187 PD-TDVRAIVVTDGERILGLGDLGHAG 264 + D++ +VV+D E ILG+GD G G Sbjct: 131 ANGRDIKLLVVSDAEGILGIGDWGVQG 157 >UniRef50_Q2HCG7 Cluster: Malic enzyme; n=1; Chaetomium globosum|Rep: Malic enzyme - Chaetomium globosum (Soil fungus) Length = 586 Score = 62.5 bits (145), Expect = 7e-09 Identities = 26/49 (53%), Positives = 38/49 (77%) Frame = +3 Query: 270 IPVGKLALYTALGGIKPHQCLPITIDVGTNTQSILDDPLYIGLRQRRVR 416 I V KLAL T GI P++ LP+ +D GT+ +++L+DPLY+GLR++RVR Sbjct: 199 ISVAKLALMTLCAGIHPNRVLPVVLDCGTDNETLLNDPLYLGLREKRVR 247 Score = 54.4 bits (125), Expect = 2e-06 Identities = 36/92 (39%), Positives = 48/92 (52%), Gaps = 21/92 (22%) Frame = +1 Query: 52 EMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNW--PDTDVRAIVVT-- 219 +M +VYTPT G A + F ++RRP+G+F+ +HD V+ L W PD D+ IVVT Sbjct: 106 KMFSVVYTPTEGDAIENFSRLFRRPQGVFLNVHDCDRVHHDLSLWGMPD-DIDYIVVTGA 164 Query: 220 -----------------DGERILGLGDLGHAG 264 DGE ILG+GD G G Sbjct: 165 TFHPRARSRLRYQLTKLDGEEILGIGDQGCGG 196 >UniRef50_Q8S484 Cluster: Putative NADP-dependent malic enzyme; n=1; Zea mays|Rep: Putative NADP-dependent malic enzyme - Zea mays (Maize) Length = 309 Score = 60.5 bits (140), Expect = 3e-08 Identities = 36/82 (43%), Positives = 44/82 (53%) Frame = +1 Query: 10 NEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWP 189 +E LFY+ + DNV E++P VYT T G V DVLKNWP Sbjct: 225 DERLFYKLLIDNVVELLPFVYTTT-------------------------GKVLDVLKNWP 259 Query: 190 DTDVRAIVVTDGERILGLGDLG 255 +++ I VTD ERILGLGDLG Sbjct: 260 HRNIQVIFVTDSERILGLGDLG 281 >UniRef50_Q4T5P0 Cluster: Malic enzyme; n=1; Tetraodon nigroviridis|Rep: Malic enzyme - Tetraodon nigroviridis (Green puffer) Length = 306 Score = 44.4 bits (100), Expect = 0.002 Identities = 18/22 (81%), Positives = 19/22 (86%) Frame = +2 Query: 509 NANAFRLLQKYRNKYCTFNDDI 574 N NAFRLL KYR+ YCTFNDDI Sbjct: 15 NINAFRLLSKYRDMYCTFNDDI 36 >UniRef50_Q5C370 Cluster: Malic enzyme; n=1; Schistosoma japonicum|Rep: Malic enzyme - Schistosoma japonicum (Blood fluke) Length = 264 Score = 40.7 bits (91), Expect = 0.024 Identities = 16/24 (66%), Positives = 21/24 (87%) Frame = +2 Query: 503 LRNANAFRLLQKYRNKYCTFNDDI 574 L+N+NAF+LL++YR Y TFNDDI Sbjct: 32 LKNSNAFQLLERYRPNYITFNDDI 55 >UniRef50_Q9S4T5 Cluster: NAD-malate oxidoreductase homolog; n=15; Legionellales|Rep: NAD-malate oxidoreductase homolog - Legionella pneumophila Length = 117 Score = 39.5 bits (88), Expect = 0.055 Identities = 14/30 (46%), Positives = 24/30 (80%) Frame = +1 Query: 4 DRNEHLFYRFVADNVAEMMPIVYTPTVGLA 93 D+N+ +FY+ ++ ++ EM+PI+YTP VG A Sbjct: 88 DKNQIVFYKLLSRHLGEMLPIIYTPIVGAA 117 >UniRef50_A0K1T3 Cluster: Allergen V5/Tpx-1 family protein precursor; n=2; Arthrobacter|Rep: Allergen V5/Tpx-1 family protein precursor - Arthrobacter sp. (strain FB24) Length = 588 Score = 34.7 bits (76), Expect = 1.6 Identities = 20/62 (32%), Positives = 29/62 (46%) Frame = +1 Query: 91 ACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPDTDVRAIVVTDGERILGLGDLGHAGWA 270 A Q G + + LF+T D+ V+D+L W D V + G L LG +GWA Sbjct: 375 AQQVVGTGFGSAKELFVTDWDRDGVFDILVQWTDGRVTLHAGSVGGGFLPGVTLGQSGWA 434 Query: 271 SL 276 + Sbjct: 435 GM 436 >UniRef50_Q1EI20 Cluster: Putative uncharacterized protein; n=2; root|Rep: Putative uncharacterized protein - uncultured organism Length = 302 Score = 32.7 bits (71), Expect = 6.3 Identities = 10/20 (50%), Positives = 16/20 (80%) Frame = +1 Query: 130 GLFITIHDKGHVYDVLKNWP 189 G+++TI + G + D+LKNWP Sbjct: 210 GVYLTIREPGQITDILKNWP 229 >UniRef50_Q5SLE4 Cluster: CBS domain protein; n=7; Bacteria|Rep: CBS domain protein - Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) Length = 143 Score = 32.7 bits (71), Expect = 6.3 Identities = 13/33 (39%), Positives = 22/33 (66%) Frame = +1 Query: 145 IHDKGHVYDVLKNWPDTDVRAIVVTDGERILGL 243 IH + V D L+ + D+ A++V +GER+LG+ Sbjct: 17 IHPEATVLDALRKLAEHDIGALLVMEGERLLGI 49 >UniRef50_A3XN08 Cluster: Putative uncharacterized protein; n=1; Leeuwenhoekiella blandensis MED217|Rep: Putative uncharacterized protein - Leeuwenhoekiella blandensis MED217 Length = 390 Score = 32.7 bits (71), Expect = 6.3 Identities = 13/33 (39%), Positives = 17/33 (51%) Frame = +1 Query: 151 DKGHVYDVLKNWPDTDVRAIVVTDGERILGLGD 249 D H D KNWPD D +++TDG + D Sbjct: 352 DVKHSSDYHKNWPDYDSEGLLITDGNYYRAMAD 384 >UniRef50_UPI0000EBCB21 Cluster: PREDICTED: similar to FELE-2, partial; n=1; Bos taurus|Rep: PREDICTED: similar to FELE-2, partial - Bos taurus Length = 1955 Score = 32.3 bits (70), Expect = 8.3 Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 4/38 (10%) Frame = +3 Query: 66 CVHSDGWPG----LSEVRPCVPPTKGPLHHDPR*GTCI 167 CV +GW G SE+ PC+ P+ G HH+ TC+ Sbjct: 299 CVCREGWTGDGRDCSEINPCLLPSAGSCHHN---ATCL 333 >UniRef50_Q4S3L6 Cluster: Chromosome 1 SCAF14749, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1 SCAF14749, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 813 Score = 32.3 bits (70), Expect = 8.3 Identities = 18/42 (42%), Positives = 23/42 (54%) Frame = +1 Query: 187 PDTDVRAIVVTDGERILGLGDLGHAGWASLLANSRSTPRSEA 312 PDT+ I+V DG+ GD G + L+ STPRSEA Sbjct: 753 PDTEDEEIIVVDGDE--EDGDTDALGGSGLVTQGVSTPRSEA 792 >UniRef50_Q8A0A0 Cluster: Putative outer membrane protein, probably involved in nutrient binding; n=1; Bacteroides thetaiotaomicron|Rep: Putative outer membrane protein, probably involved in nutrient binding - Bacteroides thetaiotaomicron Length = 1142 Score = 32.3 bits (70), Expect = 8.3 Identities = 13/35 (37%), Positives = 22/35 (62%) Frame = +3 Query: 213 CNRRRTYSGSWRLGACWMGIPVGKLALYTALGGIK 317 C + +TY+ S RLGA W G+ + + T+ GG++ Sbjct: 977 CEKNKTYNVSTRLGASWKGLAI-SANIATSWGGVR 1010 >UniRef50_A7E6G7 Cluster: Putative uncharacterized protein; n=1; Sclerotinia sclerotiorum 1980|Rep: Putative uncharacterized protein - Sclerotinia sclerotiorum 1980 Length = 421 Score = 32.3 bits (70), Expect = 8.3 Identities = 17/41 (41%), Positives = 22/41 (53%) Frame = +1 Query: 163 VYDVLKNWPDTDVRAIVVTDGERILGLGDLGHAGWASLLAN 285 + +LKN+ DT V I+V D + D GHAGW AN Sbjct: 212 IVTILKNYSDTSVILIIV-DLPNVSMYLDAGHAGWLGWSAN 251 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 559,173,755 Number of Sequences: 1657284 Number of extensions: 12056756 Number of successful extensions: 40125 Number of sequences better than 10.0: 70 Number of HSP's better than 10.0 without gapping: 38641 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 40087 length of database: 575,637,011 effective HSP length: 96 effective length of database: 416,537,747 effective search space used: 39154548218 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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